A4G23_RS25060 bae21ede5b718a73558a19f0d24670f6 281 Pfam PF14344 Domain of unknown function (DUF4397) 39 155 7.9E-25 T 10-11-2016 IPR025510 Domain of unknown function DUF4397 A4G23_RS24120 4ae190264c7fdcf5f90ee6dfff17b93d 497 Pfam PF01740 STAS domain 413 482 5.2E-6 T 10-11-2016 IPR002645 STAS domain A4G23_RS24120 4ae190264c7fdcf5f90ee6dfff17b93d 497 Gene3D G3DSA:3.30.750.24 410 484 1.3E-7 T 10-11-2016 IPR002645 STAS domain A4G23_RS24120 4ae190264c7fdcf5f90ee6dfff17b93d 497 Pfam PF00916 Sulfate permease family 161 348 1.9E-28 T 10-11-2016 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 A4G23_RS24120 4ae190264c7fdcf5f90ee6dfff17b93d 497 Pfam PF00916 Sulfate permease family 23 149 1.3E-19 T 10-11-2016 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 A4G23_RS24120 4ae190264c7fdcf5f90ee6dfff17b93d 497 SUPERFAMILY SSF52091 409 485 8.44E-11 T 10-11-2016 IPR002645 STAS domain A4G23_RS18225 139a39df13fd81f85acca0648297d694 749 SUPERFAMILY SSF53955 69 266 2.0E-62 T 10-11-2016 IPR023346 Lysozyme-like domain A4G23_RS18225 139a39df13fd81f85acca0648297d694 749 Pfam PF00912 Transglycosylase 77 253 9.6E-58 T 10-11-2016 IPR001264 Glycosyl transferase, family 51 A4G23_RS18225 139a39df13fd81f85acca0648297d694 749 Gene3D G3DSA:3.40.710.10 254 678 3.2E-95 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS18225 139a39df13fd81f85acca0648297d694 749 SUPERFAMILY SSF56601 240 257 5.07E-77 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS18225 139a39df13fd81f85acca0648297d694 749 SUPERFAMILY SSF56601 286 647 5.07E-77 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS18225 139a39df13fd81f85acca0648297d694 749 Pfam PF00905 Penicillin binding protein transpeptidase domain 352 602 1.4E-32 T 10-11-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A4G23_RS18225 139a39df13fd81f85acca0648297d694 749 Gene3D G3DSA:1.10.3810.10 77 253 3.7E-63 T 10-11-2016 A4G23_RS20375 077e86291a592b0f0541328875ee186d 325 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 8 313 28.552 T 10-11-2016 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 A4G23_RS20375 077e86291a592b0f0541328875ee186d 325 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 9 316 3.1E-82 T 10-11-2016 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 A4G23_RS20375 077e86291a592b0f0541328875ee186d 325 PIRSF PIRSF005303 4 316 7.4E-89 T 10-11-2016 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 A4G23_RS20375 077e86291a592b0f0541328875ee186d 325 SUPERFAMILY SSF55326 5 142 6.45E-34 T 10-11-2016 A4G23_RS20375 077e86291a592b0f0541328875ee186d 325 Gene3D G3DSA:3.90.650.10 151 316 8.5E-50 T 10-11-2016 IPR010918 AIR synthase-related protein, C-terminal domain A4G23_RS20375 077e86291a592b0f0541328875ee186d 325 SUPERFAMILY SSF56042 148 296 3.84E-32 T 10-11-2016 IPR010918 AIR synthase-related protein, C-terminal domain A4G23_RS20375 077e86291a592b0f0541328875ee186d 325 Gene3D G3DSA:3.30.1330.10 4 145 8.1E-45 T 10-11-2016 IPR016188 PurM-like, N-terminal domain A4G23_RS20375 077e86291a592b0f0541328875ee186d 325 Pfam PF02769 AIR synthase related protein, C-terminal domain 156 244 1.5E-5 T 10-11-2016 IPR010918 AIR synthase-related protein, C-terminal domain A4G23_RS20375 077e86291a592b0f0541328875ee186d 325 Pfam PF00586 AIR synthase related protein, N-terminal domain 33 142 7.4E-22 T 10-11-2016 IPR016188 PurM-like, N-terminal domain A4G23_RS00665 024d7d81b46a851900911f88f46ba48a 546 Gene3D G3DSA:3.40.190.10 115 208 9.1E-4 T 10-11-2016 A4G23_RS00665 024d7d81b46a851900911f88f46ba48a 546 Gene3D G3DSA:3.40.190.10 213 411 1.7E-21 T 10-11-2016 A4G23_RS00665 024d7d81b46a851900911f88f46ba48a 546 Gene3D G3DSA:3.40.190.10 490 538 1.7E-21 T 10-11-2016 A4G23_RS00665 024d7d81b46a851900911f88f46ba48a 546 Pfam PF13416 Bacterial extracellular solute-binding protein 113 389 1.2E-15 T 10-11-2016 A4G23_RS00665 024d7d81b46a851900911f88f46ba48a 546 SUPERFAMILY SSF53850 85 539 6.52E-57 T 10-11-2016 A4G23_RS07300 9e6b93fa34fa5f9bcf28e6bb91f8faa5 200 Gene3D G3DSA:1.10.3210.10 24 152 2.5E-13 T 10-11-2016 IPR006674 HD domain A4G23_RS07300 9e6b93fa34fa5f9bcf28e6bb91f8faa5 200 TIGRFAM TIGR00277 HDIG: HDIG domain 25 108 2.1E-9 T 10-11-2016 IPR006675 HDIG domain A4G23_RS07300 9e6b93fa34fa5f9bcf28e6bb91f8faa5 200 SUPERFAMILY SSF109604 27 149 3.38E-14 T 10-11-2016 A4G23_RS07300 9e6b93fa34fa5f9bcf28e6bb91f8faa5 200 SMART SM00471 22 157 1.9E-5 T 10-11-2016 IPR003607 HD/PDEase domain A4G23_RS07300 9e6b93fa34fa5f9bcf28e6bb91f8faa5 200 Pfam PF01966 HD domain 26 146 1.3E-11 T 10-11-2016 IPR006674 HD domain A4G23_RS00670 d3c7a1c32bd0b18cc77e72bfc3ead5a2 337 SUPERFAMILY SSF161098 92 319 2.22E-48 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS00670 d3c7a1c32bd0b18cc77e72bfc3ead5a2 337 Gene3D G3DSA:1.10.3720.10 98 324 2.5E-43 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS00670 d3c7a1c32bd0b18cc77e72bfc3ead5a2 337 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 126 320 1.6E-16 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS11410 540d3e95a36fdf5148df2eeb5ae76a5b 623 SUPERFAMILY SSF56059 405 612 2.12E-33 T 10-11-2016 A4G23_RS11410 540d3e95a36fdf5148df2eeb5ae76a5b 623 Pfam PF13549 ATP-grasp domain 402 613 1.5E-53 T 10-11-2016 A4G23_RS11410 540d3e95a36fdf5148df2eeb5ae76a5b 623 Gene3D G3DSA:3.30.470.20 409 509 4.7E-9 T 10-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 A4G23_RS11410 540d3e95a36fdf5148df2eeb5ae76a5b 623 SUPERFAMILY SSF52210 248 372 2.44E-10 T 10-11-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4G23_RS11410 540d3e95a36fdf5148df2eeb5ae76a5b 623 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 122 241 3.6E-14 T 10-11-2016 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain A4G23_RS11410 540d3e95a36fdf5148df2eeb5ae76a5b 623 SUPERFAMILY SSF52210 114 244 4.84E-17 T 10-11-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4G23_RS16830 e94a9766126a9a37d432679d35ceccde 357 Pfam PF04055 Radical SAM superfamily 9 146 2.4E-10 T 10-11-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 A4G23_RS16830 e94a9766126a9a37d432679d35ceccde 357 SUPERFAMILY SSF102114 9 193 8.24E-21 T 10-11-2016 A4G23_RS16830 e94a9766126a9a37d432679d35ceccde 357 Gene3D G3DSA:3.20.20.70 4 326 5.6E-22 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS14425 d1957b393b96d95a4f254d065e66a21d 398 SUPERFAMILY SSF57938 165 240 5.36E-14 T 10-11-2016 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 A4G23_RS14425 d1957b393b96d95a4f254d065e66a21d 398 SUPERFAMILY SSF46565 9 109 7.07E-30 T 10-11-2016 IPR001623 DnaJ domain A4G23_RS14425 d1957b393b96d95a4f254d065e66a21d 398 ProSitePatterns PS00636 Nt-dnaJ domain signature. 52 71 - T 10-11-2016 IPR018253 DnaJ domain, conserved site A4G23_RS14425 d1957b393b96d95a4f254d065e66a21d 398 SUPERFAMILY SSF49493 290 375 2.22E-21 T 10-11-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 A4G23_RS14425 d1957b393b96d95a4f254d065e66a21d 398 SUPERFAMILY SSF49493 145 169 8.5E-21 T 10-11-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 A4G23_RS14425 d1957b393b96d95a4f254d065e66a21d 398 SUPERFAMILY SSF49493 231 297 8.5E-21 T 10-11-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 A4G23_RS14425 d1957b393b96d95a4f254d065e66a21d 398 Gene3D G3DSA:1.10.287.110 4 97 2.1E-31 T 10-11-2016 IPR001623 DnaJ domain A4G23_RS14425 d1957b393b96d95a4f254d065e66a21d 398 Pfam PF01556 DnaJ C terminal domain 151 364 4.0E-36 T 10-11-2016 IPR002939 Chaperone DnaJ, C-terminal A4G23_RS14425 d1957b393b96d95a4f254d065e66a21d 398 SMART SM00271 9 67 2.7E-30 T 10-11-2016 IPR001623 DnaJ domain A4G23_RS14425 d1957b393b96d95a4f254d065e66a21d 398 Gene3D G3DSA:2.60.260.20 287 365 9.2E-21 T 10-11-2016 A4G23_RS14425 d1957b393b96d95a4f254d065e66a21d 398 Pfam PF00226 DnaJ domain 10 72 2.6E-27 T 10-11-2016 IPR001623 DnaJ domain A4G23_RS14425 d1957b393b96d95a4f254d065e66a21d 398 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 10 381 2.0E-122 T 10-11-2016 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 A4G23_RS14425 d1957b393b96d95a4f254d065e66a21d 398 Gene3D G3DSA:2.10.230.10 173 240 6.9E-16 T 10-11-2016 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 A4G23_RS14425 d1957b393b96d95a4f254d065e66a21d 398 PRINTS PR00625 DnaJ domain signature 67 86 4.4E-23 T 10-11-2016 IPR001623 DnaJ domain A4G23_RS14425 d1957b393b96d95a4f254d065e66a21d 398 PRINTS PR00625 DnaJ domain signature 12 30 4.4E-23 T 10-11-2016 IPR001623 DnaJ domain A4G23_RS14425 d1957b393b96d95a4f254d065e66a21d 398 PRINTS PR00625 DnaJ domain signature 47 67 4.4E-23 T 10-11-2016 IPR001623 DnaJ domain A4G23_RS14425 d1957b393b96d95a4f254d065e66a21d 398 PRINTS PR00625 DnaJ domain signature 30 45 4.4E-23 T 10-11-2016 IPR001623 DnaJ domain A4G23_RS14425 d1957b393b96d95a4f254d065e66a21d 398 Gene3D G3DSA:2.60.260.20 120 172 1.2E-22 T 10-11-2016 A4G23_RS14425 d1957b393b96d95a4f254d065e66a21d 398 Gene3D G3DSA:2.60.260.20 241 284 1.2E-22 T 10-11-2016 A4G23_RS14425 d1957b393b96d95a4f254d065e66a21d 398 Pfam PF00684 DnaJ central domain 178 238 1.1E-9 T 10-11-2016 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 A4G23_RS14425 d1957b393b96d95a4f254d065e66a21d 398 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 7 398 37.741 T 10-11-2016 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 A4G23_RS16925 be1c857dc573660556021e4cae77a5ae 542 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 527 4.1E-242 T 10-11-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 A4G23_RS16925 be1c857dc573660556021e4cae77a5ae 542 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 525 2.8E-93 T 10-11-2016 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 A4G23_RS16925 be1c857dc573660556021e4cae77a5ae 542 Gene3D G3DSA:1.10.560.10 6 194 8.1E-44 T 10-11-2016 IPR027413 GroEL-like equatorial domain A4G23_RS16925 be1c857dc573660556021e4cae77a5ae 542 Gene3D G3DSA:3.50.7.10 195 365 1.2E-87 T 10-11-2016 IPR027409 GroEL-like apical domain A4G23_RS16925 be1c857dc573660556021e4cae77a5ae 542 Hamap MF_00600 60 kDa chaperonin [groL]. 1 540 41.16 T 10-11-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 A4G23_RS16925 be1c857dc573660556021e4cae77a5ae 542 ProSitePatterns PS00296 Chaperonins cpn60 signature. 405 416 - T 10-11-2016 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020 A4G23_RS16925 be1c857dc573660556021e4cae77a5ae 542 Gene3D G3DSA:1.10.560.10 366 518 2.5E-38 T 10-11-2016 IPR027413 GroEL-like equatorial domain A4G23_RS16925 be1c857dc573660556021e4cae77a5ae 542 PRINTS PR00298 60kDa chaperonin signature 350 375 5.9E-71 T 10-11-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 A4G23_RS16925 be1c857dc573660556021e4cae77a5ae 542 PRINTS PR00298 60kDa chaperonin signature 26 52 5.9E-71 T 10-11-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 A4G23_RS16925 be1c857dc573660556021e4cae77a5ae 542 PRINTS PR00298 60kDa chaperonin signature 82 109 5.9E-71 T 10-11-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 A4G23_RS16925 be1c857dc573660556021e4cae77a5ae 542 PRINTS PR00298 60kDa chaperonin signature 268 291 5.9E-71 T 10-11-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 A4G23_RS16925 be1c857dc573660556021e4cae77a5ae 542 PRINTS PR00298 60kDa chaperonin signature 398 419 5.9E-71 T 10-11-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 A4G23_RS16925 be1c857dc573660556021e4cae77a5ae 542 SUPERFAMILY SSF54849 136 203 1.44E-24 T 10-11-2016 A4G23_RS16925 be1c857dc573660556021e4cae77a5ae 542 SUPERFAMILY SSF48592 6 133 1.08E-72 T 10-11-2016 A4G23_RS16925 be1c857dc573660556021e4cae77a5ae 542 SUPERFAMILY SSF48592 406 521 1.08E-72 T 10-11-2016 A4G23_RS16925 be1c857dc573660556021e4cae77a5ae 542 SUPERFAMILY SSF52029 184 376 1.92E-77 T 10-11-2016 IPR027409 GroEL-like apical domain A4G23_RS23540 b5e8593dfe0854c9dd8a4977c0a97232 420 SUPERFAMILY SSF103473 9 371 3.79E-13 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS23540 b5e8593dfe0854c9dd8a4977c0a97232 420 Gene3D G3DSA:1.20.1250.20 208 365 3.6E-6 T 10-11-2016 A4G23_RS02950 9ec1ecc5f55566617b7f8bc76e9d1cf9 525 Gene3D G3DSA:3.10.105.10 291 491 1.6E-41 T 10-11-2016 A4G23_RS02950 9ec1ecc5f55566617b7f8bc76e9d1cf9 525 Gene3D G3DSA:3.40.190.10 139 290 1.3E-32 T 10-11-2016 A4G23_RS02950 9ec1ecc5f55566617b7f8bc76e9d1cf9 525 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 81 440 9.1E-69 T 10-11-2016 IPR000914 Solute-binding protein family 5 domain A4G23_RS02950 9ec1ecc5f55566617b7f8bc76e9d1cf9 525 SUPERFAMILY SSF53850 30 521 3.94E-94 T 10-11-2016 A4G23_RS02950 9ec1ecc5f55566617b7f8bc76e9d1cf9 525 PIRSF PIRSF002741 4 519 6.3E-62 T 10-11-2016 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A4G23_RS07885 e631cf4ae6265d351bd1ef00603a6d81 165 Pfam PF02130 Uncharacterized protein family UPF0054 16 147 2.9E-35 T 10-11-2016 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 A4G23_RS07885 e631cf4ae6265d351bd1ef00603a6d81 165 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 2 157 21.332 T 10-11-2016 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 A4G23_RS07885 e631cf4ae6265d351bd1ef00603a6d81 165 SUPERFAMILY SSF55486 3 149 1.9E-36 T 10-11-2016 A4G23_RS07885 e631cf4ae6265d351bd1ef00603a6d81 165 Gene3D G3DSA:3.40.390.30 5 156 1.5E-42 T 10-11-2016 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 A4G23_RS07885 e631cf4ae6265d351bd1ef00603a6d81 165 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 119 129 - T 10-11-2016 IPR020549 Endoribonuclease YbeY, conserved site A4G23_RS07885 e631cf4ae6265d351bd1ef00603a6d81 165 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 36 148 3.5E-30 T 10-11-2016 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 A4G23_RS06105 5992791cc881c6b2db035cc73e41a694 321 Gene3D G3DSA:3.40.50.300 2 236 1.7E-66 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS06105 5992791cc881c6b2db035cc73e41a694 321 SMART SM00382 36 220 1.3E-10 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS06105 5992791cc881c6b2db035cc73e41a694 321 SUPERFAMILY SSF52540 22 234 1.25E-56 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS06105 5992791cc881c6b2db035cc73e41a694 321 Pfam PF00005 ABC transporter 28 170 1.5E-29 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS06105 5992791cc881c6b2db035cc73e41a694 321 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS11555 8a3de85e24d7d4c9eeb514f540a10869 637 SMART SM00878 319 423 2.8E-40 T 10-11-2016 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4G23_RS11555 8a3de85e24d7d4c9eeb514f540a10869 637 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 108 8.1E-41 T 10-11-2016 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4G23_RS11555 8a3de85e24d7d4c9eeb514f540a10869 637 SUPERFAMILY SSF56059 83 316 9.9E-55 T 10-11-2016 A4G23_RS11555 8a3de85e24d7d4c9eeb514f540a10869 637 Gene3D G3DSA:3.30.1490.20 135 187 1.6E-17 T 10-11-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A4G23_RS11555 8a3de85e24d7d4c9eeb514f540a10869 637 SUPERFAMILY SSF52440 2 113 5.9E-44 T 10-11-2016 IPR016185 Pre-ATP-grasp domain A4G23_RS11555 8a3de85e24d7d4c9eeb514f540a10869 637 Pfam PF02785 Biotin carboxylase C-terminal domain 319 421 1.6E-26 T 10-11-2016 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4G23_RS11555 8a3de85e24d7d4c9eeb514f540a10869 637 Gene3D G3DSA:3.30.470.20 188 428 6.6E-84 T 10-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 A4G23_RS11555 8a3de85e24d7d4c9eeb514f540a10869 637 Gene3D G3DSA:3.40.50.20 2 122 1.4E-42 T 10-11-2016 IPR016185 Pre-ATP-grasp domain A4G23_RS11555 8a3de85e24d7d4c9eeb514f540a10869 637 SUPERFAMILY SSF51246 313 429 2.51E-30 T 10-11-2016 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4G23_RS11555 8a3de85e24d7d4c9eeb514f540a10869 637 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 134 307 3.7E-58 T 10-11-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A4G23_RS11555 8a3de85e24d7d4c9eeb514f540a10869 637 Pfam PF00364 Biotin-requiring enzyme 573 636 6.5E-13 T 10-11-2016 IPR000089 Biotin/lipoyl attachment A4G23_RS11555 8a3de85e24d7d4c9eeb514f540a10869 637 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 271 278 - T 10-11-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A4G23_RS11555 8a3de85e24d7d4c9eeb514f540a10869 637 SUPERFAMILY SSF51230 558 636 3.93E-17 T 10-11-2016 IPR011053 Single hybrid motif A4G23_RS11555 8a3de85e24d7d4c9eeb514f540a10869 637 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 595 612 - T 10-11-2016 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4G23_RS11555 8a3de85e24d7d4c9eeb514f540a10869 637 Gene3D G3DSA:2.40.50.100 569 637 2.9E-19 T 10-11-2016 A4G23_RS27140 545dc7f7ac942747a22ce71b72ca4cc7 139 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 11 129 3.9E-29 T 10-11-2016 IPR019920 F420-binding domain, putative A4G23_RS27140 545dc7f7ac942747a22ce71b72ca4cc7 139 Gene3D G3DSA:2.30.110.10 6 134 8.8E-28 T 10-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 A4G23_RS27140 545dc7f7ac942747a22ce71b72ca4cc7 139 SUPERFAMILY SSF50475 6 132 2.98E-28 T 10-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 A4G23_RS27140 545dc7f7ac942747a22ce71b72ca4cc7 139 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 6 93 8.3E-14 T 10-11-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 A4G23_RS17155 a595af2b06a6704fecfe9b5b6a6a19bc 392 Hamap MF_00558 Succinyl-CoA ligase [ADP-forming] subunit beta [sucC]. 1 390 40.514 T 10-11-2016 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A4G23_RS17155 a595af2b06a6704fecfe9b5b6a6a19bc 392 SUPERFAMILY SSF52210 232 389 2.09E-42 T 10-11-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4G23_RS17155 a595af2b06a6704fecfe9b5b6a6a19bc 392 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 250 274 - T 10-11-2016 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4G23_RS17155 a595af2b06a6704fecfe9b5b6a6a19bc 392 Gene3D G3DSA:3.40.50.261 233 389 4.5E-53 T 10-11-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4G23_RS17155 a595af2b06a6704fecfe9b5b6a6a19bc 392 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 2 389 7.7E-122 T 10-11-2016 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A4G23_RS17155 a595af2b06a6704fecfe9b5b6a6a19bc 392 Gene3D G3DSA:3.30.1490.20 22 85 1.2E-17 T 10-11-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A4G23_RS17155 a595af2b06a6704fecfe9b5b6a6a19bc 392 Pfam PF00549 CoA-ligase 257 376 1.9E-13 T 10-11-2016 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4G23_RS17155 a595af2b06a6704fecfe9b5b6a6a19bc 392 Pfam PF08442 ATP-grasp domain 2 195 3.4E-68 T 10-11-2016 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A4G23_RS17155 a595af2b06a6704fecfe9b5b6a6a19bc 392 PIRSF PIRSF001554 1 392 2.6E-135 T 10-11-2016 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A4G23_RS17155 a595af2b06a6704fecfe9b5b6a6a19bc 392 Gene3D G3DSA:3.30.470.20 86 229 3.5E-49 T 10-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 A4G23_RS17155 a595af2b06a6704fecfe9b5b6a6a19bc 392 SUPERFAMILY SSF56059 3 227 8.37E-62 T 10-11-2016 A4G23_RS24365 2a078859892c919818df0aebf3bc457e 663 Gene3D G3DSA:2.120.10.30 103 376 1.8E-18 T 10-11-2016 IPR011042 Six-bladed beta-propeller, TolB-like A4G23_RS24365 2a078859892c919818df0aebf3bc457e 663 Pfam PF00326 Prolyl oligopeptidase family 444 650 1.9E-41 T 10-11-2016 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 A4G23_RS24365 2a078859892c919818df0aebf3bc457e 663 SUPERFAMILY SSF53474 390 649 1.97E-57 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS24365 2a078859892c919818df0aebf3bc457e 663 SUPERFAMILY SSF82171 92 374 8.83E-17 T 10-11-2016 A4G23_RS24365 2a078859892c919818df0aebf3bc457e 663 Pfam PF07676 WD40-like Beta Propeller Repeat 190 203 0.31 T 10-11-2016 IPR011659 WD40-like Beta Propeller A4G23_RS24365 2a078859892c919818df0aebf3bc457e 663 Pfam PF07676 WD40-like Beta Propeller Repeat 248 268 0.22 T 10-11-2016 IPR011659 WD40-like Beta Propeller A4G23_RS24365 2a078859892c919818df0aebf3bc457e 663 Gene3D G3DSA:3.40.50.1820 390 639 2.5E-56 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS10605 fca5857836119f03936764ad0ec715d8 393 Gene3D G3DSA:3.30.70.890 219 390 5.4E-50 T 10-11-2016 IPR013750 GHMP kinase, C-terminal domain A4G23_RS10605 fca5857836119f03936764ad0ec715d8 393 Pfam PF00288 GHMP kinases N terminal domain 122 188 2.6E-16 T 10-11-2016 IPR006204 GHMP kinase N-terminal domain GO:0005524 A4G23_RS10605 fca5857836119f03936764ad0ec715d8 393 SUPERFAMILY SSF55060 215 391 4.5E-44 T 10-11-2016 IPR013750 GHMP kinase, C-terminal domain A4G23_RS10605 fca5857836119f03936764ad0ec715d8 393 Pfam PF10509 Galactokinase galactose-binding signature 15 62 2.7E-17 T 10-11-2016 IPR019539 Galactokinase galactose-binding domain KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A4G23_RS10605 fca5857836119f03936764ad0ec715d8 393 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 129 140 - T 10-11-2016 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 A4G23_RS10605 fca5857836119f03936764ad0ec715d8 393 TIGRFAM TIGR00131 gal_kin: galactokinase 12 368 1.5E-79 T 10-11-2016 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A4G23_RS10605 fca5857836119f03936764ad0ec715d8 393 PIRSF PIRSF000530 2 393 9.0E-114 T 10-11-2016 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A4G23_RS10605 fca5857836119f03936764ad0ec715d8 393 Pfam PF08544 GHMP kinases C terminal 292 371 5.0E-11 T 10-11-2016 IPR013750 GHMP kinase, C-terminal domain A4G23_RS10605 fca5857836119f03936764ad0ec715d8 393 Gene3D G3DSA:3.30.230.10 10 218 4.8E-71 T 10-11-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A4G23_RS10605 fca5857836119f03936764ad0ec715d8 393 PRINTS PR00473 Galactokinase signature 100 111 7.9E-19 T 10-11-2016 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A4G23_RS10605 fca5857836119f03936764ad0ec715d8 393 PRINTS PR00473 Galactokinase signature 275 289 7.9E-19 T 10-11-2016 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A4G23_RS10605 fca5857836119f03936764ad0ec715d8 393 PRINTS PR00473 Galactokinase signature 120 138 7.9E-19 T 10-11-2016 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A4G23_RS10605 fca5857836119f03936764ad0ec715d8 393 PRINTS PR00473 Galactokinase signature 32 50 7.9E-19 T 10-11-2016 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A4G23_RS10605 fca5857836119f03936764ad0ec715d8 393 PRINTS PR00959 Mevalonate kinase family signature 30 54 2.9E-39 T 10-11-2016 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A4G23_RS10605 fca5857836119f03936764ad0ec715d8 393 PRINTS PR00959 Mevalonate kinase family signature 127 149 2.9E-39 T 10-11-2016 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A4G23_RS10605 fca5857836119f03936764ad0ec715d8 393 PRINTS PR00959 Mevalonate kinase family signature 170 189 2.9E-39 T 10-11-2016 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A4G23_RS10605 fca5857836119f03936764ad0ec715d8 393 PRINTS PR00959 Mevalonate kinase family signature 338 355 2.9E-39 T 10-11-2016 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A4G23_RS10605 fca5857836119f03936764ad0ec715d8 393 SUPERFAMILY SSF54211 9 210 2.43E-56 T 10-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold A4G23_RS02870 206fe3a40a107d1f9b65eab918704109 178 SUPERFAMILY SSF51161 8 173 1.8E-47 T 10-11-2016 IPR011004 Trimeric LpxA-like A4G23_RS02870 206fe3a40a107d1f9b65eab918704109 178 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 92 125 2.3E-6 T 10-11-2016 IPR001451 Hexapeptide repeat A4G23_RS02870 206fe3a40a107d1f9b65eab918704109 178 Gene3D G3DSA:2.160.10.10 7 173 2.1E-47 T 10-11-2016 A4G23_RS10655 7fd497559aa5e9ea094fa6ee6920ae24 297 Hamap MF_00061 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 3 287 29.248 T 10-11-2016 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 A4G23_RS10655 7fd497559aa5e9ea094fa6ee6920ae24 297 Gene3D G3DSA:3.30.230.10 3 159 8.4E-49 T 10-11-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A4G23_RS10655 7fd497559aa5e9ea094fa6ee6920ae24 297 Pfam PF08544 GHMP kinases C terminal 202 275 5.2E-7 T 10-11-2016 IPR013750 GHMP kinase, C-terminal domain A4G23_RS10655 7fd497559aa5e9ea094fa6ee6920ae24 297 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 3 269 5.4E-46 T 10-11-2016 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 A4G23_RS10655 7fd497559aa5e9ea094fa6ee6920ae24 297 SUPERFAMILY SSF54211 2 157 1.9E-40 T 10-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold A4G23_RS10655 7fd497559aa5e9ea094fa6ee6920ae24 297 SUPERFAMILY SSF55060 165 275 1.37E-20 T 10-11-2016 IPR013750 GHMP kinase, C-terminal domain A4G23_RS10655 7fd497559aa5e9ea094fa6ee6920ae24 297 PIRSF PIRSF010376 1 294 1.2E-75 T 10-11-2016 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 A4G23_RS10655 7fd497559aa5e9ea094fa6ee6920ae24 297 Pfam PF00288 GHMP kinases N terminal domain 87 145 1.5E-4 T 10-11-2016 IPR006204 GHMP kinase N-terminal domain GO:0005524 A4G23_RS10655 7fd497559aa5e9ea094fa6ee6920ae24 297 Gene3D G3DSA:3.30.70.890 165 278 3.9E-24 T 10-11-2016 IPR013750 GHMP kinase, C-terminal domain A4G23_RS07370 65663a197f981fb4f6b408d8127cc636 274 Gene3D G3DSA:3.40.50.1000 7 108 2.6E-8 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS07370 65663a197f981fb4f6b408d8127cc636 274 Gene3D G3DSA:3.40.50.1000 184 234 2.6E-8 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS07370 65663a197f981fb4f6b408d8127cc636 274 PIRSF PIRSF030802 3 246 1.7E-16 T 10-11-2016 IPR024197 Uncharacterised conserved protein UCP030802 A4G23_RS07370 65663a197f981fb4f6b408d8127cc636 274 SUPERFAMILY SSF56784 44 231 1.15E-15 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS07370 65663a197f981fb4f6b408d8127cc636 274 SUPERFAMILY SSF56784 6 17 1.15E-15 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS05955 2de18783074e60b300832c9ff5b9eed8 486 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 474 1.2E-206 T 10-11-2016 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 A4G23_RS05955 2de18783074e60b300832c9ff5b9eed8 486 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 146 456 5.7E-34 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS05955 2de18783074e60b300832c9ff5b9eed8 486 Gene3D G3DSA:3.50.50.60 235 399 1.9E-41 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS05955 2de18783074e60b300832c9ff5b9eed8 486 SUPERFAMILY SSF46548 6 155 2.28E-36 T 10-11-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 A4G23_RS05955 2de18783074e60b300832c9ff5b9eed8 486 Gene3D G3DSA:1.10.1060.10 2 147 7.7E-37 T 10-11-2016 A4G23_RS05955 2de18783074e60b300832c9ff5b9eed8 486 SUPERFAMILY SSF51971 144 400 1.65E-67 T 10-11-2016 A4G23_RS05955 2de18783074e60b300832c9ff5b9eed8 486 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 40 131 1.2E-20 T 10-11-2016 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 A4G23_RS05955 2de18783074e60b300832c9ff5b9eed8 486 PRINTS PR00419 Adrenodoxin reductase family signature 285 299 1.0E-24 T 10-11-2016 A4G23_RS05955 2de18783074e60b300832c9ff5b9eed8 486 PRINTS PR00419 Adrenodoxin reductase family signature 146 168 1.0E-24 T 10-11-2016 A4G23_RS05955 2de18783074e60b300832c9ff5b9eed8 486 PRINTS PR00419 Adrenodoxin reductase family signature 169 182 1.0E-24 T 10-11-2016 A4G23_RS05955 2de18783074e60b300832c9ff5b9eed8 486 PRINTS PR00419 Adrenodoxin reductase family signature 211 221 1.0E-24 T 10-11-2016 A4G23_RS05955 2de18783074e60b300832c9ff5b9eed8 486 Gene3D G3DSA:3.40.50.720 148 234 5.1E-47 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS05955 2de18783074e60b300832c9ff5b9eed8 486 Gene3D G3DSA:3.40.50.720 400 481 5.1E-47 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS19190 da8418de1103c5173d47e7b9918162a3 487 SUPERFAMILY SSF51445 200 385 7.75E-47 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS19190 da8418de1103c5173d47e7b9918162a3 487 SUPERFAMILY SSF51445 60 166 7.75E-47 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS19190 da8418de1103c5173d47e7b9918162a3 487 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 92 357 1.7E-24 T 10-11-2016 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 A4G23_RS19190 da8418de1103c5173d47e7b9918162a3 487 Gene3D G3DSA:3.20.20.80 200 393 1.7E-47 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS19190 da8418de1103c5173d47e7b9918162a3 487 Gene3D G3DSA:3.20.20.80 72 167 1.7E-47 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS23730 ca5b65e3d72cd2cc715d38d7c498bd83 274 SMART SM00116 29 77 7.9E-10 T 10-11-2016 IPR000644 CBS domain A4G23_RS23730 ca5b65e3d72cd2cc715d38d7c498bd83 274 SMART SM00116 116 164 1.1E-13 T 10-11-2016 IPR000644 CBS domain A4G23_RS23730 ca5b65e3d72cd2cc715d38d7c498bd83 274 Pfam PF04972 BON domain 166 230 1.2E-6 T 10-11-2016 IPR007055 BON domain A4G23_RS23730 ca5b65e3d72cd2cc715d38d7c498bd83 274 Pfam PF00571 CBS domain 110 163 6.3E-16 T 10-11-2016 IPR000644 CBS domain A4G23_RS23730 ca5b65e3d72cd2cc715d38d7c498bd83 274 Pfam PF00571 CBS domain 22 76 4.4E-15 T 10-11-2016 IPR000644 CBS domain A4G23_RS23730 ca5b65e3d72cd2cc715d38d7c498bd83 274 Gene3D G3DSA:3.20.20.70 19 169 5.0E-37 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS23730 ca5b65e3d72cd2cc715d38d7c498bd83 274 SUPERFAMILY SSF54631 14 169 1.52E-36 T 10-11-2016 A4G23_RS02770 38d423a0b4afc8b49e7388d6c8c93f8a 252 Pfam PF00392 Bacterial regulatory proteins, gntR family 25 75 5.7E-16 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS02770 38d423a0b4afc8b49e7388d6c8c93f8a 252 SMART SM00345 17 75 1.3E-12 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS02770 38d423a0b4afc8b49e7388d6c8c93f8a 252 SMART SM00866 93 239 2.4E-9 T 10-11-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A4G23_RS02770 38d423a0b4afc8b49e7388d6c8c93f8a 252 SUPERFAMILY SSF64288 63 242 2.98E-23 T 10-11-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain A4G23_RS02770 38d423a0b4afc8b49e7388d6c8c93f8a 252 Gene3D G3DSA:3.40.1410.10 97 241 6.1E-20 T 10-11-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain A4G23_RS02770 38d423a0b4afc8b49e7388d6c8c93f8a 252 SUPERFAMILY SSF46785 12 83 3.36E-17 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS02770 38d423a0b4afc8b49e7388d6c8c93f8a 252 Gene3D G3DSA:1.10.10.10 10 79 3.0E-20 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS02770 38d423a0b4afc8b49e7388d6c8c93f8a 252 Pfam PF07702 UTRA domain 126 237 1.8E-11 T 10-11-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A4G23_RS02770 38d423a0b4afc8b49e7388d6c8c93f8a 252 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 65 2.1E-10 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS02770 38d423a0b4afc8b49e7388d6c8c93f8a 252 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 35 49 2.1E-10 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS15765 a42f4ea8e98d3cc51469e93c918feef4 586 TIGRFAM TIGR00467 lysS_arch: lysine--tRNA ligase 223 584 8.4E-55 T 10-11-2016 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 A4G23_RS15765 a42f4ea8e98d3cc51469e93c918feef4 586 Gene3D G3DSA:3.40.50.620 323 372 8.0E-4 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS15765 a42f4ea8e98d3cc51469e93c918feef4 586 SUPERFAMILY SSF52374 219 370 3.07E-49 T 10-11-2016 A4G23_RS15765 a42f4ea8e98d3cc51469e93c918feef4 586 SUPERFAMILY SSF52374 26 176 3.07E-49 T 10-11-2016 A4G23_RS15765 a42f4ea8e98d3cc51469e93c918feef4 586 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 51 - T 10-11-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4G23_RS15765 a42f4ea8e98d3cc51469e93c918feef4 586 SUPERFAMILY SSF48163 376 584 3.14E-22 T 10-11-2016 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 A4G23_RS15765 a42f4ea8e98d3cc51469e93c918feef4 586 Gene3D G3DSA:2.30.30.300 229 262 4.1E-8 T 10-11-2016 IPR023386 Lysine-tRNA ligase, insertion domain GO:0004824 KEGG: 00970+6.1.1.6 A4G23_RS15765 a42f4ea8e98d3cc51469e93c918feef4 586 Gene3D G3DSA:3.40.50.620 271 322 3.3E-56 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS15765 a42f4ea8e98d3cc51469e93c918feef4 586 Gene3D G3DSA:3.40.50.620 20 173 3.3E-56 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS15765 a42f4ea8e98d3cc51469e93c918feef4 586 Gene3D G3DSA:3.40.50.620 221 228 3.3E-56 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS15765 a42f4ea8e98d3cc51469e93c918feef4 586 Hamap MF_00177 Lysine--tRNA ligase [lysS]. 11 586 31.055 T 10-11-2016 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 A4G23_RS15765 a42f4ea8e98d3cc51469e93c918feef4 586 Pfam PF01921 tRNA synthetases class I (K) 12 411 1.2E-127 T 10-11-2016 A4G23_RS15765 a42f4ea8e98d3cc51469e93c918feef4 586 Gene3D G3DSA:1.10.10.350 495 585 2.8E-19 T 10-11-2016 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 A4G23_RS05350 c3be0f49c0af28c034da1ddb67a243c9 318 SUPERFAMILY SSF53850 91 293 4.48E-17 T 10-11-2016 A4G23_RS05350 c3be0f49c0af28c034da1ddb67a243c9 318 Gene3D G3DSA:3.40.190.10 92 176 3.2E-14 T 10-11-2016 A4G23_RS05350 c3be0f49c0af28c034da1ddb67a243c9 318 SUPERFAMILY SSF46785 2 86 1.32E-17 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS05350 c3be0f49c0af28c034da1ddb67a243c9 318 Gene3D G3DSA:1.10.10.10 2 87 6.3E-23 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS05350 c3be0f49c0af28c034da1ddb67a243c9 318 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 64 1.1E-15 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS05350 c3be0f49c0af28c034da1ddb67a243c9 318 Gene3D G3DSA:3.40.190.10 177 212 7.0E-4 T 10-11-2016 A4G23_RS05350 c3be0f49c0af28c034da1ddb67a243c9 318 Pfam PF03466 LysR substrate binding domain 89 288 1.7E-18 T 10-11-2016 IPR005119 LysR, substrate-binding A4G23_RS01085 66ac52a6de0074e00130d7831e809ea1 428 Gene3D G3DSA:1.20.1250.20 269 397 2.2E-10 T 10-11-2016 A4G23_RS01085 66ac52a6de0074e00130d7831e809ea1 428 Gene3D G3DSA:1.20.1250.20 6 185 2.1E-13 T 10-11-2016 A4G23_RS01085 66ac52a6de0074e00130d7831e809ea1 428 Pfam PF05977 Transmembrane secretion effector 4 181 6.1E-18 T 10-11-2016 IPR010290 Transmembrane secretion effector A4G23_RS01085 66ac52a6de0074e00130d7831e809ea1 428 SUPERFAMILY SSF103473 3 400 2.62E-33 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS05300 40834e6d3d482d9a3939367746022909 704 TIGRFAM TIGR02442 Cob-chelat-sub: cobaltochelatase subunit 6 683 9.2E-252 T 10-11-2016 IPR012804 Cobaltochelatase subunit, putative A4G23_RS05300 40834e6d3d482d9a3939367746022909 704 SMART SM00382 29 206 2.0E-7 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS05300 40834e6d3d482d9a3939367746022909 704 Gene3D G3DSA:3.40.50.300 5 202 1.8E-55 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05300 40834e6d3d482d9a3939367746022909 704 SUPERFAMILY SSF52540 5 332 2.61E-58 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05300 40834e6d3d482d9a3939367746022909 704 SMART SM00327 518 695 1.3E-20 T 10-11-2016 IPR002035 von Willebrand factor, type A A4G23_RS05300 40834e6d3d482d9a3939367746022909 704 Pfam PF13519 von Willebrand factor type A domain 521 627 8.1E-17 T 10-11-2016 IPR002035 von Willebrand factor, type A A4G23_RS05300 40834e6d3d482d9a3939367746022909 704 SUPERFAMILY SSF53300 521 683 4.01E-23 T 10-11-2016 IPR002035 von Willebrand factor, type A A4G23_RS05300 40834e6d3d482d9a3939367746022909 704 Pfam PF01078 Magnesium chelatase, subunit ChlI 114 183 6.8E-8 T 10-11-2016 IPR000523 Magnesium chelatase ChlI domain A4G23_RS05300 40834e6d3d482d9a3939367746022909 704 Gene3D G3DSA:1.10.8.80 249 335 5.0E-34 T 10-11-2016 A4G23_RS05300 40834e6d3d482d9a3939367746022909 704 Gene3D G3DSA:3.40.50.410 521 643 8.7E-14 T 10-11-2016 IPR002035 von Willebrand factor, type A A4G23_RS18005 b92b0fd12852d177d93e08b45d3611fa 679 Gene3D G3DSA:1.50.10.10 213 326 7.5E-11 T 10-11-2016 IPR012341 Six-hairpin glycosidase GO:0003824 A4G23_RS18005 b92b0fd12852d177d93e08b45d3611fa 679 SUPERFAMILY SSF48208 186 538 5.44E-61 T 10-11-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 A4G23_RS18005 b92b0fd12852d177d93e08b45d3611fa 679 SUPERFAMILY SSF52833 1 128 5.09E-30 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS18005 b92b0fd12852d177d93e08b45d3611fa 679 Pfam PF03190 Protein of unknown function, DUF255 3 163 1.4E-74 T 10-11-2016 IPR004879 Domain of unknown function DUF255 A4G23_RS18005 b92b0fd12852d177d93e08b45d3611fa 679 Gene3D G3DSA:3.40.30.10 20 145 2.5E-32 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS18005 b92b0fd12852d177d93e08b45d3611fa 679 PIRSF PIRSF006402 1 679 9.0E-191 T 10-11-2016 IPR024705 Spermatogenesis-associated protein 20 A4G23_RS01500 f6bafee1d5e2062c187b4403e4ec8c46 398 Pfam PF00970 Oxidoreductase FAD-binding domain 158 259 1.0E-10 T 10-11-2016 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 A4G23_RS01500 f6bafee1d5e2062c187b4403e4ec8c46 398 Gene3D G3DSA:2.40.30.10 154 261 7.8E-33 T 10-11-2016 A4G23_RS01500 f6bafee1d5e2062c187b4403e4ec8c46 398 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 206 213 5.9E-5 T 10-11-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A4G23_RS01500 f6bafee1d5e2062c187b4403e4ec8c46 398 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 356 364 5.9E-5 T 10-11-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A4G23_RS01500 f6bafee1d5e2062c187b4403e4ec8c46 398 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 186 196 5.9E-5 T 10-11-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A4G23_RS01500 f6bafee1d5e2062c187b4403e4ec8c46 398 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 269 288 5.9E-5 T 10-11-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A4G23_RS01500 f6bafee1d5e2062c187b4403e4ec8c46 398 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 306 317 5.9E-5 T 10-11-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A4G23_RS01500 f6bafee1d5e2062c187b4403e4ec8c46 398 Gene3D G3DSA:1.10.490.10 2 146 3.2E-43 T 10-11-2016 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 A4G23_RS01500 f6bafee1d5e2062c187b4403e4ec8c46 398 SUPERFAMILY SSF46458 2 144 3.16E-30 T 10-11-2016 IPR009050 Globin-like A4G23_RS01500 f6bafee1d5e2062c187b4403e4ec8c46 398 Pfam PF00042 Globin 10 105 5.6E-7 T 10-11-2016 IPR000971 Globin GO:0019825|GO:0020037 A4G23_RS01500 f6bafee1d5e2062c187b4403e4ec8c46 398 Gene3D G3DSA:3.40.50.80 262 391 1.3E-32 T 10-11-2016 A4G23_RS01500 f6bafee1d5e2062c187b4403e4ec8c46 398 SUPERFAMILY SSF52343 262 390 1.14E-34 T 10-11-2016 A4G23_RS01500 f6bafee1d5e2062c187b4403e4ec8c46 398 SUPERFAMILY SSF63380 154 261 1.34E-27 T 10-11-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 A4G23_RS01500 f6bafee1d5e2062c187b4403e4ec8c46 398 Pfam PF00175 Oxidoreductase NAD-binding domain 272 370 7.5E-13 T 10-11-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 A4G23_RS01500 f6bafee1d5e2062c187b4403e4ec8c46 398 PRINTS PR00410 Phenol hydroxylase reductase family signature 269 288 1.2E-6 T 10-11-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 A4G23_RS01500 f6bafee1d5e2062c187b4403e4ec8c46 398 PRINTS PR00410 Phenol hydroxylase reductase family signature 186 198 1.2E-6 T 10-11-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 A4G23_RS01500 f6bafee1d5e2062c187b4403e4ec8c46 398 PRINTS PR00410 Phenol hydroxylase reductase family signature 356 364 1.2E-6 T 10-11-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 A4G23_RS18735 8170579652732144aaca69cf08ff2055 131 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 66 128 2.1E-16 T 10-11-2016 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 A4G23_RS18735 8170579652732144aaca69cf08ff2055 131 Pfam PF03459 TOBE domain 66 128 3.1E-16 T 10-11-2016 IPR005116 Transport-associated OB, type 1 A4G23_RS18735 8170579652732144aaca69cf08ff2055 131 Gene3D G3DSA:2.40.50.100 66 128 8.6E-23 T 10-11-2016 A4G23_RS18735 8170579652732144aaca69cf08ff2055 131 Pfam PF12728 Helix-turn-helix domain 4 49 2.1E-8 T 10-11-2016 A4G23_RS18735 8170579652732144aaca69cf08ff2055 131 SUPERFAMILY SSF46955 3 53 5.49E-10 T 10-11-2016 IPR009061 Putative DNA-binding domain A4G23_RS18735 8170579652732144aaca69cf08ff2055 131 SUPERFAMILY SSF50331 66 128 9.23E-17 T 10-11-2016 IPR008995 Molybdate/tungstate binding, C-terminal A4G23_RS18735 8170579652732144aaca69cf08ff2055 131 Gene3D G3DSA:1.10.1660.10 4 47 1.5E-5 T 10-11-2016 A4G23_RS11205 30edd75dc1d93480588671af2c5db864 200 Gene3D G3DSA:2.60.120.10 3 191 1.2E-54 T 10-11-2016 IPR014710 RmlC-like jelly roll fold A4G23_RS11205 30edd75dc1d93480588671af2c5db864 200 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 6 178 1.9E-48 T 10-11-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 A4G23_RS11205 30edd75dc1d93480588671af2c5db864 200 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 198 2.0E-52 T 10-11-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 A4G23_RS11205 30edd75dc1d93480588671af2c5db864 200 SUPERFAMILY SSF51182 2 199 8.9E-62 T 10-11-2016 IPR011051 RmlC-like cupin domain A4G23_RS07710 17564cfa3c773d1585c15c9a4c9b3906 109 Pfam PF03091 CutA1 divalent ion tolerance protein 9 105 7.4E-33 T 10-11-2016 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 A4G23_RS07710 17564cfa3c773d1585c15c9a4c9b3906 109 Gene3D G3DSA:3.30.70.830 6 106 4.6E-36 T 10-11-2016 A4G23_RS07710 17564cfa3c773d1585c15c9a4c9b3906 109 SUPERFAMILY SSF54913 6 106 2.11E-33 T 10-11-2016 IPR011322 Nitrogen regulatory PII-like, alpha/beta A4G23_RS01450 a2d3caaf4f34ae4a286e2e79717bff8c 658 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 343 349 - T 10-11-2016 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 A4G23_RS01450 a2d3caaf4f34ae4a286e2e79717bff8c 658 Gene3D G3DSA:3.40.1110.10 356 467 2.5E-22 T 10-11-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A4G23_RS01450 a2d3caaf4f34ae4a286e2e79717bff8c 658 Pfam PF00702 haloacid dehalogenase-like hydrolase 337 554 2.6E-43 T 10-11-2016 A4G23_RS01450 a2d3caaf4f34ae4a286e2e79717bff8c 658 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 90 644 6.5E-177 T 10-11-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A4G23_RS01450 a2d3caaf4f34ae4a286e2e79717bff8c 658 SUPERFAMILY SSF81653 145 240 1.7E-24 T 10-11-2016 A4G23_RS01450 a2d3caaf4f34ae4a286e2e79717bff8c 658 Pfam PF00122 E1-E2 ATPase 112 332 8.2E-57 T 10-11-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 A4G23_RS01450 a2d3caaf4f34ae4a286e2e79717bff8c 658 Gene3D G3DSA:3.40.50.1000 468 605 1.5E-40 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS01450 a2d3caaf4f34ae4a286e2e79717bff8c 658 Gene3D G3DSA:3.40.50.1000 317 355 1.5E-40 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS01450 a2d3caaf4f34ae4a286e2e79717bff8c 658 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 114 605 9.7E-70 T 10-11-2016 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A4G23_RS01450 a2d3caaf4f34ae4a286e2e79717bff8c 658 Gene3D G3DSA:2.70.150.10 93 242 4.9E-26 T 10-11-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 A4G23_RS01450 a2d3caaf4f34ae4a286e2e79717bff8c 658 SUPERFAMILY SSF56784 340 422 7.65E-51 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS01450 a2d3caaf4f34ae4a286e2e79717bff8c 658 SUPERFAMILY SSF56784 456 641 7.65E-51 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS01450 a2d3caaf4f34ae4a286e2e79717bff8c 658 ProSitePatterns PS01229 Hypothetical cof family signature 2. 541 563 - T 10-11-2016 A4G23_RS01450 a2d3caaf4f34ae4a286e2e79717bff8c 658 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 488 498 1.1E-23 T 10-11-2016 A4G23_RS01450 a2d3caaf4f34ae4a286e2e79717bff8c 658 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 191 205 1.1E-23 T 10-11-2016 A4G23_RS01450 a2d3caaf4f34ae4a286e2e79717bff8c 658 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 541 560 1.1E-23 T 10-11-2016 A4G23_RS01450 a2d3caaf4f34ae4a286e2e79717bff8c 658 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 341 355 1.1E-23 T 10-11-2016 A4G23_RS01450 a2d3caaf4f34ae4a286e2e79717bff8c 658 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 565 577 1.1E-23 T 10-11-2016 A4G23_RS01450 a2d3caaf4f34ae4a286e2e79717bff8c 658 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 465 476 1.1E-23 T 10-11-2016 A4G23_RS01450 a2d3caaf4f34ae4a286e2e79717bff8c 658 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 541 557 9.6E-6 T 10-11-2016 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A4G23_RS01450 a2d3caaf4f34ae4a286e2e79717bff8c 658 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 513 529 9.6E-6 T 10-11-2016 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A4G23_RS01450 a2d3caaf4f34ae4a286e2e79717bff8c 658 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 573 598 9.6E-6 T 10-11-2016 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A4G23_RS26795 d7584126715b6fd93c358d83eecd430d 237 Gene3D G3DSA:1.10.357.10 3 190 4.1E-33 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS26795 d7584126715b6fd93c358d83eecd430d 237 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 2.0E-9 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS26795 d7584126715b6fd93c358d83eecd430d 237 SUPERFAMILY SSF48498 82 205 9.54E-20 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS26795 d7584126715b6fd93c358d83eecd430d 237 SUPERFAMILY SSF46689 3 84 2.05E-13 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS26795 d7584126715b6fd93c358d83eecd430d 237 ProSitePatterns PS01081 TetR-type HTH domain signature. 26 56 - T 10-11-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A4G23_RS26795 d7584126715b6fd93c358d83eecd430d 237 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 4.3E-6 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS26795 d7584126715b6fd93c358d83eecd430d 237 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 4.3E-6 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS02900 cf2622ead256df419c8ff3cd88761732 391 SUPERFAMILY SSF50465 302 390 1.06E-24 T 10-11-2016 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal A4G23_RS02900 cf2622ead256df419c8ff3cd88761732 391 SUPERFAMILY SSF50447 206 300 7.27E-27 T 10-11-2016 IPR009000 Translation protein, beta-barrel domain A4G23_RS02900 cf2622ead256df419c8ff3cd88761732 391 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 391 3.6E-170 T 10-11-2016 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A4G23_RS02900 cf2622ead256df419c8ff3cd88761732 391 Gene3D G3DSA:2.40.30.10 301 390 1.3E-30 T 10-11-2016 A4G23_RS02900 cf2622ead256df419c8ff3cd88761732 391 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 14 150 1.5E-12 T 10-11-2016 IPR005225 Small GTP-binding protein domain GO:0005525 A4G23_RS02900 cf2622ead256df419c8ff3cd88761732 391 PRINTS PR00315 GTP-binding elongation factor signature 80 90 3.3E-23 T 10-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4G23_RS02900 cf2622ead256df419c8ff3cd88761732 391 PRINTS PR00315 GTP-binding elongation factor signature 96 107 3.3E-23 T 10-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4G23_RS02900 cf2622ead256df419c8ff3cd88761732 391 PRINTS PR00315 GTP-binding elongation factor signature 14 27 3.3E-23 T 10-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4G23_RS02900 cf2622ead256df419c8ff3cd88761732 391 PRINTS PR00315 GTP-binding elongation factor signature 60 68 3.3E-23 T 10-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4G23_RS02900 cf2622ead256df419c8ff3cd88761732 391 PRINTS PR00315 GTP-binding elongation factor signature 133 142 3.3E-23 T 10-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4G23_RS02900 cf2622ead256df419c8ff3cd88761732 391 SUPERFAMILY SSF52540 7 219 1.66E-54 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS02900 cf2622ead256df419c8ff3cd88761732 391 Gene3D G3DSA:2.40.30.10 213 297 7.1E-31 T 10-11-2016 A4G23_RS02900 cf2622ead256df419c8ff3cd88761732 391 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 391 52.48 T 10-11-2016 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A4G23_RS02900 cf2622ead256df419c8ff3cd88761732 391 Pfam PF03144 Elongation factor Tu domain 2 226 292 7.7E-13 T 10-11-2016 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A4G23_RS02900 cf2622ead256df419c8ff3cd88761732 391 Gene3D G3DSA:3.40.50.300 8 212 1.6E-60 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS02900 cf2622ead256df419c8ff3cd88761732 391 Pfam PF00009 Elongation factor Tu GTP binding domain 10 202 5.5E-53 T 10-11-2016 A4G23_RS02900 cf2622ead256df419c8ff3cd88761732 391 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 53 68 - T 10-11-2016 IPR031157 Tr-type G domain, conserved site A4G23_RS02900 cf2622ead256df419c8ff3cd88761732 391 Pfam PF03143 Elongation factor Tu C-terminal domain 298 390 2.4E-21 T 10-11-2016 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal A4G23_RS06240 4700ed76ddba330766ebf8cdf846a776 362 SUPERFAMILY SSF53756 2 358 8.75E-99 T 10-11-2016 A4G23_RS06240 4700ed76ddba330766ebf8cdf846a776 362 Gene3D G3DSA:3.40.50.2000 187 339 4.9E-18 T 10-11-2016 A4G23_RS06240 4700ed76ddba330766ebf8cdf846a776 362 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 188 348 1.4E-39 T 10-11-2016 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 A4G23_RS06240 4700ed76ddba330766ebf8cdf846a776 362 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 2 351 9.3E-88 T 10-11-2016 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4G23_RS06240 4700ed76ddba330766ebf8cdf846a776 362 Gene3D G3DSA:3.40.50.2000 2 186 2.1E-60 T 10-11-2016 A4G23_RS06240 4700ed76ddba330766ebf8cdf846a776 362 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 3 358 31.554 T 10-11-2016 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4G23_RS06240 4700ed76ddba330766ebf8cdf846a776 362 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 3 141 5.2E-43 T 10-11-2016 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4G23_RS08425 964b2dd0f9145a06fa5b815c21d56f8c 342 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 2 116 2.1E-29 T 10-11-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 A4G23_RS08425 964b2dd0f9145a06fa5b815c21d56f8c 342 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 2 337 1.5E-128 T 10-11-2016 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A4G23_RS08425 964b2dd0f9145a06fa5b815c21d56f8c 342 SUPERFAMILY SSF51735 2 153 1.64E-44 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS08425 964b2dd0f9145a06fa5b815c21d56f8c 342 SMART SM00859 2 117 1.5E-38 T 10-11-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 A4G23_RS08425 964b2dd0f9145a06fa5b815c21d56f8c 342 PIRSF PIRSF000148 1 341 1.6E-107 T 10-11-2016 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A4G23_RS08425 964b2dd0f9145a06fa5b815c21d56f8c 342 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 240 254 - T 10-11-2016 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A4G23_RS08425 964b2dd0f9145a06fa5b815c21d56f8c 342 Gene3D G3DSA:3.30.360.10 139 319 1.5E-67 T 10-11-2016 A4G23_RS08425 964b2dd0f9145a06fa5b815c21d56f8c 342 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 136 323 1.1E-51 T 10-11-2016 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A4G23_RS08425 964b2dd0f9145a06fa5b815c21d56f8c 342 SUPERFAMILY SSF55347 126 324 4.97E-59 T 10-11-2016 A4G23_RS08425 964b2dd0f9145a06fa5b815c21d56f8c 342 Gene3D G3DSA:3.40.50.720 1 138 1.6E-58 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS08425 964b2dd0f9145a06fa5b815c21d56f8c 342 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 1 337 32.809 T 10-11-2016 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A4G23_RS16800 6a8acd0d9990b0661f23b63e76a81323 493 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 1 202 20.622 T 10-11-2016 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 A4G23_RS16800 6a8acd0d9990b0661f23b63e76a81323 493 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 215 488 20.247 T 10-11-2016 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 A4G23_RS16800 6a8acd0d9990b0661f23b63e76a81323 493 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 15 201 4.5E-28 T 10-11-2016 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 A4G23_RS16800 6a8acd0d9990b0661f23b63e76a81323 493 ProSitePatterns PS01049 YjeF C-terminal domain signature 1. 298 308 - T 10-11-2016 IPR017953 Carbohydrate kinase, predicted, conserved site A4G23_RS16800 6a8acd0d9990b0661f23b63e76a81323 493 SUPERFAMILY SSF53613 215 484 1.52E-54 T 10-11-2016 IPR029056 Ribokinase-like A4G23_RS16800 6a8acd0d9990b0661f23b63e76a81323 493 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 219 456 1.4E-45 T 10-11-2016 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 A4G23_RS16800 6a8acd0d9990b0661f23b63e76a81323 493 SUPERFAMILY SSF64153 5 236 5.62E-48 T 10-11-2016 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 A4G23_RS16800 6a8acd0d9990b0661f23b63e76a81323 493 Pfam PF01256 Carbohydrate kinase 238 456 1.2E-50 T 10-11-2016 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 A4G23_RS16800 6a8acd0d9990b0661f23b63e76a81323 493 Pfam PF03853 YjeF-related protein N-terminus 25 181 4.1E-39 T 10-11-2016 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 A4G23_RS16800 6a8acd0d9990b0661f23b63e76a81323 493 PIRSF PIRSF017184 1 474 1.4E-100 T 10-11-2016 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 A4G23_RS16800 6a8acd0d9990b0661f23b63e76a81323 493 Gene3D G3DSA:3.40.1190.20 210 485 2.7E-78 T 10-11-2016 IPR029056 Ribokinase-like A4G23_RS16800 6a8acd0d9990b0661f23b63e76a81323 493 Gene3D G3DSA:3.40.50.10260 3 202 1.8E-57 T 10-11-2016 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 A4G23_RS13875 449e38c3a8b4dbe19df4aaf5e6d2e232 549 Gene3D G3DSA:2.30.38.10 357 438 6.7E-18 T 10-11-2016 A4G23_RS13875 449e38c3a8b4dbe19df4aaf5e6d2e232 549 Gene3D G3DSA:3.40.50.980 191 339 3.2E-36 T 10-11-2016 A4G23_RS13875 449e38c3a8b4dbe19df4aaf5e6d2e232 549 SUPERFAMILY SSF56801 8 541 1.14E-136 T 10-11-2016 A4G23_RS13875 449e38c3a8b4dbe19df4aaf5e6d2e232 549 ProSitePatterns PS00455 Putative AMP-binding domain signature. 184 195 - T 10-11-2016 IPR020845 AMP-binding, conserved site A4G23_RS13875 449e38c3a8b4dbe19df4aaf5e6d2e232 549 Gene3D G3DSA:3.30.300.30 439 539 9.8E-29 T 10-11-2016 A4G23_RS13875 449e38c3a8b4dbe19df4aaf5e6d2e232 549 Pfam PF13193 AMP-binding enzyme C-terminal domain 453 529 1.4E-18 T 10-11-2016 IPR025110 AMP-binding enzyme C-terminal domain A4G23_RS13875 449e38c3a8b4dbe19df4aaf5e6d2e232 549 Pfam PF00501 AMP-binding enzyme 36 444 2.0E-85 T 10-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A4G23_RS13875 449e38c3a8b4dbe19df4aaf5e6d2e232 549 Gene3D G3DSA:3.40.50.980 48 190 2.1E-28 T 10-11-2016 A4G23_RS25495 eb1f663c301eceaecc4962c3b8e416d9 881 Gene3D G3DSA:3.40.50.740 511 537 3.4E-78 T 10-11-2016 A4G23_RS25495 eb1f663c301eceaecc4962c3b8e416d9 881 Gene3D G3DSA:3.40.50.740 260 332 3.4E-78 T 10-11-2016 A4G23_RS25495 eb1f663c301eceaecc4962c3b8e416d9 881 Gene3D G3DSA:3.40.50.740 570 720 3.4E-78 T 10-11-2016 A4G23_RS25495 eb1f663c301eceaecc4962c3b8e416d9 881 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 19 36 - T 10-11-2016 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS25495 eb1f663c301eceaecc4962c3b8e416d9 881 Gene3D G3DSA:3.30.70.20 94 128 4.6E-4 T 10-11-2016 A4G23_RS25495 eb1f663c301eceaecc4962c3b8e416d9 881 Gene3D G3DSA:3.30.70.20 179 213 6.7E-5 T 10-11-2016 A4G23_RS25495 eb1f663c301eceaecc4962c3b8e416d9 881 Pfam PF01568 Molydopterin dinucleotide binding domain 770 874 4.5E-24 T 10-11-2016 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 A4G23_RS25495 eb1f663c301eceaecc4962c3b8e416d9 881 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 205 255 6.1E-16 T 10-11-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS25495 eb1f663c301eceaecc4962c3b8e416d9 881 Gene3D G3DSA:3.10.20.30 1 40 3.7E-4 T 10-11-2016 IPR012675 Beta-grasp domain A4G23_RS25495 eb1f663c301eceaecc4962c3b8e416d9 881 SUPERFAMILY SSF53706 203 772 4.97E-187 T 10-11-2016 A4G23_RS25495 eb1f663c301eceaecc4962c3b8e416d9 881 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 629 646 - T 10-11-2016 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 A4G23_RS25495 eb1f663c301eceaecc4962c3b8e416d9 881 Gene3D G3DSA:3.40.228.10 334 510 4.6E-53 T 10-11-2016 A4G23_RS25495 eb1f663c301eceaecc4962c3b8e416d9 881 Gene3D G3DSA:2.20.25.90 214 258 3.6E-18 T 10-11-2016 A4G23_RS25495 eb1f663c301eceaecc4962c3b8e416d9 881 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 172 183 - T 10-11-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4G23_RS25495 eb1f663c301eceaecc4962c3b8e416d9 881 Gene3D G3DSA:2.40.40.20 723 878 4.3E-40 T 10-11-2016 A4G23_RS25495 eb1f663c301eceaecc4962c3b8e416d9 881 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 1 61 5.7E-10 T 10-11-2016 A4G23_RS25495 eb1f663c301eceaecc4962c3b8e416d9 881 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 208 878 6.7E-222 T 10-11-2016 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.2.1.2|KEGG: 00680+1.2.1.2|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696 A4G23_RS25495 eb1f663c301eceaecc4962c3b8e416d9 881 Gene3D G3DSA:3.30.70.20 129 178 6.9E-15 T 10-11-2016 A4G23_RS25495 eb1f663c301eceaecc4962c3b8e416d9 881 Pfam PF00384 Molybdopterin oxidoreductase 260 683 2.3E-82 T 10-11-2016 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS25495 eb1f663c301eceaecc4962c3b8e416d9 881 Pfam PF13187 4Fe-4S dicluster domain 129 187 8.6E-7 T 10-11-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4G23_RS25495 eb1f663c301eceaecc4962c3b8e416d9 881 SUPERFAMILY SSF54292 1 86 9.19E-16 T 10-11-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A4G23_RS25495 eb1f663c301eceaecc4962c3b8e416d9 881 PIRSF PIRSF036643 1 880 1.1E-287 T 10-11-2016 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.2.1.2|KEGG: 00680+1.2.1.2|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696 A4G23_RS25495 eb1f663c301eceaecc4962c3b8e416d9 881 SMART SM00926 203 257 3.6E-16 T 10-11-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS25495 eb1f663c301eceaecc4962c3b8e416d9 881 SUPERFAMILY SSF50692 742 878 1.39E-37 T 10-11-2016 IPR009010 Aspartate decarboxylase-like domain A4G23_RS25495 eb1f663c301eceaecc4962c3b8e416d9 881 SUPERFAMILY SSF54862 115 188 3.77E-23 T 10-11-2016 A4G23_RS04955 8053920618f40609e307f4d58bfb4a2a 271 SUPERFAMILY SSF53335 64 251 5.73E-22 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS04955 8053920618f40609e307f4d58bfb4a2a 271 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 8 245 9.4E-60 T 10-11-2016 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 A4G23_RS04955 8053920618f40609e307f4d58bfb4a2a 271 Pfam PF01479 S4 domain 7 49 6.1E-11 T 10-11-2016 IPR002942 RNA-binding S4 domain GO:0003723 A4G23_RS04955 8053920618f40609e307f4d58bfb4a2a 271 SUPERFAMILY SSF55174 6 60 4.56E-12 T 10-11-2016 A4G23_RS04955 8053920618f40609e307f4d58bfb4a2a 271 Gene3D G3DSA:3.10.290.10 7 98 4.8E-24 T 10-11-2016 IPR002942 RNA-binding S4 domain GO:0003723 A4G23_RS04955 8053920618f40609e307f4d58bfb4a2a 271 SMART SM00363 7 74 2.2E-7 T 10-11-2016 IPR002942 RNA-binding S4 domain GO:0003723 A4G23_RS04955 8053920618f40609e307f4d58bfb4a2a 271 PIRSF PIRSF005578 3 268 2.0E-93 T 10-11-2016 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 A4G23_RS04955 8053920618f40609e307f4d58bfb4a2a 271 Pfam PF01728 FtsJ-like methyltransferase 65 250 8.9E-18 T 10-11-2016 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 A4G23_RS04955 8053920618f40609e307f4d58bfb4a2a 271 Gene3D G3DSA:3.40.50.150 99 181 9.6E-7 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS07780 7aa62dd6f178c0094b0d7e8cf6852db3 342 Gene3D G3DSA:1.10.10.10 259 321 4.0E-10 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS07780 7aa62dd6f178c0094b0d7e8cf6852db3 342 SMART SM00418 254 322 3.8E-4 T 10-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4G23_RS07780 7aa62dd6f178c0094b0d7e8cf6852db3 342 Pfam PF12840 Helix-turn-helix domain 259 306 1.2E-7 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS07780 7aa62dd6f178c0094b0d7e8cf6852db3 342 SUPERFAMILY SSF46785 257 323 1.3E-9 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS13220 651bebd14b5bb0636a81f92e280193ec 424 Pfam PF03454 MoeA C-terminal region (domain IV) 358 423 9.4E-10 T 10-11-2016 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4G23_RS13220 651bebd14b5bb0636a81f92e280193ec 424 Pfam PF00994 Probable molybdopterin binding domain 212 346 3.5E-23 T 10-11-2016 IPR001453 MoaB/Mog domain A4G23_RS13220 651bebd14b5bb0636a81f92e280193ec 424 SUPERFAMILY SSF63882 33 206 1.26E-34 T 10-11-2016 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4G23_RS13220 651bebd14b5bb0636a81f92e280193ec 424 SUPERFAMILY SSF53218 208 351 1.7E-28 T 10-11-2016 IPR001453 MoaB/Mog domain A4G23_RS13220 651bebd14b5bb0636a81f92e280193ec 424 Gene3D G3DSA:3.90.105.10 162 193 2.7E-14 T 10-11-2016 A4G23_RS13220 651bebd14b5bb0636a81f92e280193ec 424 SUPERFAMILY SSF63867 355 423 8.37E-8 T 10-11-2016 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4G23_RS13220 651bebd14b5bb0636a81f92e280193ec 424 Gene3D G3DSA:3.40.980.10 194 358 6.0E-44 T 10-11-2016 IPR001453 MoaB/Mog domain A4G23_RS13220 651bebd14b5bb0636a81f92e280193ec 424 Pfam PF03453 MoeA N-terminal region (domain I and II) 42 198 5.2E-30 T 10-11-2016 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4G23_RS13220 651bebd14b5bb0636a81f92e280193ec 424 Gene3D G3DSA:2.40.340.10 359 422 1.3E-7 T 10-11-2016 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4G23_RS13220 651bebd14b5bb0636a81f92e280193ec 424 SMART SM00852 211 347 6.3E-24 T 10-11-2016 IPR001453 MoaB/Mog domain A4G23_RS13220 651bebd14b5bb0636a81f92e280193ec 424 Gene3D G3DSA:2.170.190.11 72 161 3.8E-19 T 10-11-2016 A4G23_RS01370 8fcd3af41e46500ce04729b6d7ee6b68 407 SUPERFAMILY SSF69318 135 400 1.83E-16 T 10-11-2016 A4G23_RS01370 8fcd3af41e46500ce04729b6d7ee6b68 407 Gene3D G3DSA:2.115.10.10 166 354 2.9E-17 T 10-11-2016 IPR023294 Tachylectin 2 A4G23_RS15890 13239741d2476007080583b6c1d97f23 226 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 95 216 2.2E-34 T 10-11-2016 IPR004507 Flavin prenyltransferase UbiX/Pad1 A4G23_RS15890 13239741d2476007080583b6c1d97f23 226 Pfam PF02441 Flavoprotein 12 160 7.9E-23 T 10-11-2016 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 A4G23_RS15890 13239741d2476007080583b6c1d97f23 226 SUPERFAMILY SSF52507 11 218 1.96E-45 T 10-11-2016 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 A4G23_RS15890 13239741d2476007080583b6c1d97f23 226 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 10 218 30.556 T 10-11-2016 IPR004507 Flavin prenyltransferase UbiX/Pad1 A4G23_RS15890 13239741d2476007080583b6c1d97f23 226 Gene3D G3DSA:3.40.50.1950 11 219 9.2E-65 T 10-11-2016 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 A4G23_RS22840 0e8f779e2be74b4cd682e4682c047522 1427 SMART SM00487 135 390 0.0018 T 10-11-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4G23_RS22840 0e8f779e2be74b4cd682e4682c047522 1427 TIGRFAM TIGR02547 casA_cse1: CRISPR type I-E/ECOLI-associated protein CasA/Cse1 883 1374 1.2E-57 T 10-11-2016 IPR013381 CRISPR-associated protein Cse1 A4G23_RS22840 0e8f779e2be74b4cd682e4682c047522 1427 Pfam PF09481 CRISPR-associated protein Cse1 (CRISPR_cse1) 883 1375 2.2E-113 T 10-11-2016 IPR013381 CRISPR-associated protein Cse1 A4G23_RS22840 0e8f779e2be74b4cd682e4682c047522 1427 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 282 538 2.1E-41 T 10-11-2016 IPR006474 Helicase Cas3, CRISPR-associated, core A4G23_RS22840 0e8f779e2be74b4cd682e4682c047522 1427 Gene3D G3DSA:3.40.50.300 277 367 1.2E-10 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS22840 0e8f779e2be74b4cd682e4682c047522 1427 Gene3D G3DSA:3.40.50.300 136 227 1.2E-10 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS22840 0e8f779e2be74b4cd682e4682c047522 1427 Gene3D G3DSA:3.40.50.300 425 538 3.6E-5 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS22840 0e8f779e2be74b4cd682e4682c047522 1427 SUPERFAMILY SSF52540 270 362 3.2E-26 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS22840 0e8f779e2be74b4cd682e4682c047522 1427 SUPERFAMILY SSF52540 155 207 3.2E-26 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS22840 0e8f779e2be74b4cd682e4682c047522 1427 SUPERFAMILY SSF52540 404 541 3.2E-26 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS07665 ef601d7101275aa29ccc42cc5ad224e0 577 ProSitePatterns PS00211 ABC transporters family signature. 472 486 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS07665 ef601d7101275aa29ccc42cc5ad224e0 577 Pfam PF00005 ABC transporter 351 498 1.3E-24 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS07665 ef601d7101275aa29ccc42cc5ad224e0 577 Gene3D G3DSA:1.20.1560.10 10 315 7.2E-63 T 10-11-2016 A4G23_RS07665 ef601d7101275aa29ccc42cc5ad224e0 577 Gene3D G3DSA:3.40.50.300 334 564 4.3E-71 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS07665 ef601d7101275aa29ccc42cc5ad224e0 577 SUPERFAMILY SSF90123 9 315 5.49E-70 T 10-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A4G23_RS07665 ef601d7101275aa29ccc42cc5ad224e0 577 Pfam PF00664 ABC transporter transmembrane region 19 288 5.7E-42 T 10-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A4G23_RS07665 ef601d7101275aa29ccc42cc5ad224e0 577 SMART SM00382 360 552 4.7E-12 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS07665 ef601d7101275aa29ccc42cc5ad224e0 577 SUPERFAMILY SSF52540 327 570 1.5E-80 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS08025 0c3b843fe58d6e691b2f2f1e9e638bc7 281 SUPERFAMILY SSF82549 5 279 2.62E-75 T 10-11-2016 A4G23_RS08025 0c3b843fe58d6e691b2f2f1e9e638bc7 281 Gene3D G3DSA:3.40.50.10170 5 150 2.8E-44 T 10-11-2016 A4G23_RS08025 0c3b843fe58d6e691b2f2f1e9e638bc7 281 Gene3D G3DSA:3.30.1180.10 155 280 3.3E-40 T 10-11-2016 A4G23_RS08025 0c3b843fe58d6e691b2f2f1e9e638bc7 281 Pfam PF02645 Uncharacterised protein, DegV family COG1307 5 279 4.6E-85 T 10-11-2016 IPR003797 DegV A4G23_RS08025 0c3b843fe58d6e691b2f2f1e9e638bc7 281 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 5 278 1.1E-85 T 10-11-2016 IPR003797 DegV A4G23_RS03775 3714b6fd16f902b0f84b6e883ae3c822 729 SMART SM00838 639 727 2.3E-21 T 10-11-2016 IPR000640 Translation elongation factor EFG, V domain A4G23_RS03775 3714b6fd16f902b0f84b6e883ae3c822 729 SMART SM00889 519 637 5.7E-56 T 10-11-2016 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 A4G23_RS03775 3714b6fd16f902b0f84b6e883ae3c822 729 Gene3D G3DSA:2.40.30.10 333 444 1.5E-28 T 10-11-2016 A4G23_RS03775 3714b6fd16f902b0f84b6e883ae3c822 729 SUPERFAMILY SSF54980 443 520 4.32E-18 T 10-11-2016 IPR009022 Elongation factor G, III-V domain A4G23_RS03775 3714b6fd16f902b0f84b6e883ae3c822 729 SUPERFAMILY SSF54980 640 727 1.94E-21 T 10-11-2016 IPR009022 Elongation factor G, III-V domain A4G23_RS03775 3714b6fd16f902b0f84b6e883ae3c822 729 PRINTS PR00315 GTP-binding elongation factor signature 92 102 3.6E-6 T 10-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4G23_RS03775 3714b6fd16f902b0f84b6e883ae3c822 729 PRINTS PR00315 GTP-binding elongation factor signature 108 119 3.6E-6 T 10-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4G23_RS03775 3714b6fd16f902b0f84b6e883ae3c822 729 PRINTS PR00315 GTP-binding elongation factor signature 26 39 3.6E-6 T 10-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4G23_RS03775 3714b6fd16f902b0f84b6e883ae3c822 729 Gene3D G3DSA:3.30.70.870 445 515 5.0E-25 T 10-11-2016 A4G23_RS03775 3714b6fd16f902b0f84b6e883ae3c822 729 Pfam PF00679 Elongation factor G C-terminus 640 726 1.3E-21 T 10-11-2016 IPR000640 Translation elongation factor EFG, V domain A4G23_RS03775 3714b6fd16f902b0f84b6e883ae3c822 729 SUPERFAMILY SSF52540 21 310 5.54E-51 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS03775 3714b6fd16f902b0f84b6e883ae3c822 729 Pfam PF14492 Elongation Factor G, domain II 443 514 1.0E-24 T 10-11-2016 IPR009022 Elongation factor G, III-V domain A4G23_RS03775 3714b6fd16f902b0f84b6e883ae3c822 729 Gene3D G3DSA:3.30.230.10 523 639 2.0E-45 T 10-11-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A4G23_RS03775 3714b6fd16f902b0f84b6e883ae3c822 729 Pfam PF03764 Elongation factor G, domain IV 519 634 1.3E-38 T 10-11-2016 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 A4G23_RS03775 3714b6fd16f902b0f84b6e883ae3c822 729 Pfam PF03144 Elongation factor Tu domain 2 353 429 4.8E-11 T 10-11-2016 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A4G23_RS03775 3714b6fd16f902b0f84b6e883ae3c822 729 Gene3D G3DSA:3.40.50.300 19 316 1.6E-55 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS03775 3714b6fd16f902b0f84b6e883ae3c822 729 SUPERFAMILY SSF50447 329 439 6.56E-24 T 10-11-2016 IPR009000 Translation protein, beta-barrel domain A4G23_RS03775 3714b6fd16f902b0f84b6e883ae3c822 729 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 25 158 7.3E-13 T 10-11-2016 IPR005225 Small GTP-binding protein domain GO:0005525 A4G23_RS03775 3714b6fd16f902b0f84b6e883ae3c822 729 SUPERFAMILY SSF54211 519 634 4.8E-34 T 10-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold A4G23_RS03775 3714b6fd16f902b0f84b6e883ae3c822 729 Gene3D G3DSA:3.30.70.240 640 725 2.8E-23 T 10-11-2016 IPR000640 Translation elongation factor EFG, V domain A4G23_RS03775 3714b6fd16f902b0f84b6e883ae3c822 729 Pfam PF00009 Elongation factor Tu GTP binding domain 23 172 3.2E-27 T 10-11-2016 A4G23_RS26665 dd151753c6dc02878898818357dde0c6 641 SMART SM00220 15 275 5.7E-52 T 10-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4G23_RS26665 dd151753c6dc02878898818357dde0c6 641 Gene3D G3DSA:3.30.200.20 9 104 3.8E-22 T 10-11-2016 A4G23_RS26665 dd151753c6dc02878898818357dde0c6 641 SUPERFAMILY SSF56112 12 354 3.24E-64 T 10-11-2016 IPR011009 Protein kinase-like domain A4G23_RS26665 dd151753c6dc02878898818357dde0c6 641 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 143 155 - T 10-11-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 A4G23_RS26665 dd151753c6dc02878898818357dde0c6 641 Pfam PF00069 Protein kinase domain 16 233 5.1E-40 T 10-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4G23_RS26665 dd151753c6dc02878898818357dde0c6 641 Gene3D G3DSA:1.10.510.10 112 346 1.4E-38 T 10-11-2016 A4G23_RS26665 dd151753c6dc02878898818357dde0c6 641 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 21 44 - T 10-11-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 A4G23_RS19100 61df33c6457225eaf7fca045d5bce182 390 SUPERFAMILY SSF53474 24 134 7.17E-43 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS19100 61df33c6457225eaf7fca045d5bce182 390 SUPERFAMILY SSF53474 164 378 7.17E-43 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS19100 61df33c6457225eaf7fca045d5bce182 390 Gene3D G3DSA:3.40.50.1820 167 378 3.2E-33 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS19100 61df33c6457225eaf7fca045d5bce182 390 Pfam PF12146 Serine aminopeptidase, S33 168 276 6.2E-8 T 10-11-2016 IPR022742 Serine aminopeptidase, S33 A4G23_RS19100 61df33c6457225eaf7fca045d5bce182 390 Gene3D G3DSA:1.20.1440.110 43 116 7.9E-4 T 10-11-2016 A4G23_RS08390 6418a8a2264c9ebebc15c53757ee84fa 848 SUPERFAMILY SSF63737 8 199 1.57E-36 T 10-11-2016 A4G23_RS08390 6418a8a2264c9ebebc15c53757ee84fa 848 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 318 330 6.2E-18 T 10-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4G23_RS08390 6418a8a2264c9ebebc15c53757ee84fa 848 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 182 197 6.2E-18 T 10-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4G23_RS08390 6418a8a2264c9ebebc15c53757ee84fa 848 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 299 314 6.2E-18 T 10-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4G23_RS08390 6418a8a2264c9ebebc15c53757ee84fa 848 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 139 154 6.2E-18 T 10-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4G23_RS08390 6418a8a2264c9ebebc15c53757ee84fa 848 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 265 275 6.2E-18 T 10-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4G23_RS08390 6418a8a2264c9ebebc15c53757ee84fa 848 TIGRFAM TIGR02412 pepN_strep_liv: aminopeptidase N 5 844 0.0 T 10-11-2016 IPR012778 Peptidase M1, aminopeptidase GO:0004177|GO:0006508 KEGG: 00480+3.4.11.2|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112 A4G23_RS08390 6418a8a2264c9ebebc15c53757ee84fa 848 Pfam PF11838 ERAP1-like C-terminal domain 526 837 4.7E-60 T 10-11-2016 IPR024571 ERAP1-like C-terminal domain A4G23_RS08390 6418a8a2264c9ebebc15c53757ee84fa 848 SUPERFAMILY SSF55486 213 457 5.62E-75 T 10-11-2016 A4G23_RS08390 6418a8a2264c9ebebc15c53757ee84fa 848 Pfam PF01433 Peptidase family M1 105 391 1.4E-65 T 10-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4G23_RS08390 6418a8a2264c9ebebc15c53757ee84fa 848 Gene3D G3DSA:1.10.390.10 312 458 6.0E-42 T 10-11-2016 A4G23_RS13280 30487ebfe93430617c1ebf6589a80902 329 TIGRFAM TIGR02156 PA_CoA_Oxy1: phenylacetate-CoA oxygenase, PaaG subunit 16 304 2.6E-159 T 10-11-2016 IPR011881 1,2-phenylacetyl-CoA epoxidase, subunit A GO:0010124|GO:0097266 KEGG: 00360+1.14.13.14+1.14.13.149|KEGG: 00940+1.14.13.14|MetaCyc: PWY-5176 A4G23_RS13280 30487ebfe93430617c1ebf6589a80902 329 SUPERFAMILY SSF47240 36 279 7.3E-86 T 10-11-2016 IPR009078 Ferritin-like superfamily A4G23_RS13280 30487ebfe93430617c1ebf6589a80902 329 Gene3D G3DSA:1.20.1260.10 26 281 1.3E-107 T 10-11-2016 IPR012347 Ferritin-related A4G23_RS13280 30487ebfe93430617c1ebf6589a80902 329 Pfam PF05138 Phenylacetic acid catabolic protein 26 300 7.2E-108 T 10-11-2016 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 A4G23_RS04430 0d85687ce6649f57a7fd0aa1a880a794 329 SUPERFAMILY SSF51430 1 318 1.57E-89 T 10-11-2016 IPR023210 NADP-dependent oxidoreductase domain A4G23_RS04430 0d85687ce6649f57a7fd0aa1a880a794 329 Gene3D G3DSA:3.20.20.100 9 323 2.9E-88 T 10-11-2016 IPR023210 NADP-dependent oxidoreductase domain A4G23_RS04430 0d85687ce6649f57a7fd0aa1a880a794 329 Pfam PF00248 Aldo/keto reductase family 15 313 4.8E-59 T 10-11-2016 IPR023210 NADP-dependent oxidoreductase domain A4G23_RS02390 81433b36945f68a27bcc8d0e1d043d96 979 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 574 585 - T 10-11-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4G23_RS02390 81433b36945f68a27bcc8d0e1d043d96 979 Pfam PF13183 4Fe-4S dicluster domain 572 642 3.9E-9 T 10-11-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4G23_RS02390 81433b36945f68a27bcc8d0e1d043d96 979 SUPERFAMILY SSF55103 300 555 9.48E-44 T 10-11-2016 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 A4G23_RS02390 81433b36945f68a27bcc8d0e1d043d96 979 SUPERFAMILY SSF56176 35 294 2.73E-52 T 10-11-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 A4G23_RS02390 81433b36945f68a27bcc8d0e1d043d96 979 Gene3D G3DSA:1.10.1060.10 538 654 2.6E-18 T 10-11-2016 A4G23_RS02390 81433b36945f68a27bcc8d0e1d043d96 979 Gene3D G3DSA:3.30.43.10 25 121 1.3E-14 T 10-11-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 A4G23_RS02390 81433b36945f68a27bcc8d0e1d043d96 979 Gene3D G3DSA:3.30.465.10 133 294 6.2E-22 T 10-11-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 A4G23_RS02390 81433b36945f68a27bcc8d0e1d043d96 979 Gene3D G3DSA:1.10.45.10 511 537 1.1E-5 T 10-11-2016 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 A4G23_RS02390 81433b36945f68a27bcc8d0e1d043d96 979 Pfam PF02754 Cysteine-rich domain 878 956 0.12 T 10-11-2016 IPR004017 Cysteine-rich domain A4G23_RS02390 81433b36945f68a27bcc8d0e1d043d96 979 SUPERFAMILY SSF46548 537 654 2.62E-17 T 10-11-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 A4G23_RS02390 81433b36945f68a27bcc8d0e1d043d96 979 Pfam PF02913 FAD linked oxidases, C-terminal domain 297 548 2.5E-48 T 10-11-2016 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 A4G23_RS02390 81433b36945f68a27bcc8d0e1d043d96 979 Pfam PF01565 FAD binding domain 71 207 1.1E-28 T 10-11-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 A4G23_RS20595 0c98d96c8897f7ede06f286a7a107f31 254 Hamap MF_01220_B Uridylate kinase [pyrH]. 14 248 42.748 T 10-11-2016 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 A4G23_RS20595 0c98d96c8897f7ede06f286a7a107f31 254 SUPERFAMILY SSF53633 18 249 1.57E-68 T 10-11-2016 IPR001048 Aspartate/glutamate/uridylate kinase A4G23_RS20595 0c98d96c8897f7ede06f286a7a107f31 254 Gene3D G3DSA:3.40.1160.10 13 248 4.8E-82 T 10-11-2016 IPR001048 Aspartate/glutamate/uridylate kinase A4G23_RS20595 0c98d96c8897f7ede06f286a7a107f31 254 Pfam PF00696 Amino acid kinase family 18 226 3.6E-26 T 10-11-2016 IPR001048 Aspartate/glutamate/uridylate kinase A4G23_RS20595 0c98d96c8897f7ede06f286a7a107f31 254 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 18 248 2.6E-90 T 10-11-2016 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 A4G23_RS20595 0c98d96c8897f7ede06f286a7a107f31 254 PIRSF PIRSF005650 11 254 1.5E-88 T 10-11-2016 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 A4G23_RS09315 eb2a33f043996b0d8cdab1db7129e293 353 Gene3D G3DSA:3.40.50.720 1 130 7.8E-38 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS09315 eb2a33f043996b0d8cdab1db7129e293 353 Gene3D G3DSA:3.30.360.10 131 347 1.4E-39 T 10-11-2016 A4G23_RS09315 eb2a33f043996b0d8cdab1db7129e293 353 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 134 225 4.3E-12 T 10-11-2016 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 A4G23_RS09315 eb2a33f043996b0d8cdab1db7129e293 353 SUPERFAMILY SSF55347 129 282 1.96E-27 T 10-11-2016 A4G23_RS09315 eb2a33f043996b0d8cdab1db7129e293 353 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 1 120 6.0E-22 T 10-11-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 A4G23_RS09315 eb2a33f043996b0d8cdab1db7129e293 353 SUPERFAMILY SSF51735 1 157 2.63E-43 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS15965 ebf1627d385f26833eaaa13488241f55 78 SMART SM00530 15 70 2.2E-10 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS15965 ebf1627d385f26833eaaa13488241f55 78 SUPERFAMILY SSF47413 10 76 7.78E-16 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS15965 ebf1627d385f26833eaaa13488241f55 78 Gene3D G3DSA:1.10.260.40 6 75 4.8E-17 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS15965 ebf1627d385f26833eaaa13488241f55 78 Pfam PF13560 Helix-turn-helix domain 11 66 2.6E-14 T 10-11-2016 A4G23_RS25690 035c64f81628ab5ba370aba4978c1d61 455 SUPERFAMILY SSF53955 41 120 2.72E-29 T 10-11-2016 IPR023346 Lysozyme-like domain A4G23_RS25690 035c64f81628ab5ba370aba4978c1d61 455 Gene3D G3DSA:3.10.350.10 158 206 2.4E-8 T 10-11-2016 IPR018392 LysM domain A4G23_RS25690 035c64f81628ab5ba370aba4978c1d61 455 Pfam PF01551 Peptidase family M23 347 444 5.6E-32 T 10-11-2016 IPR016047 Peptidase M23 A4G23_RS25690 035c64f81628ab5ba370aba4978c1d61 455 SMART SM00257 158 207 8.9E-6 T 10-11-2016 IPR018392 LysM domain A4G23_RS25690 035c64f81628ab5ba370aba4978c1d61 455 Gene3D G3DSA:1.10.530.10 24 120 1.9E-38 T 10-11-2016 A4G23_RS25690 035c64f81628ab5ba370aba4978c1d61 455 Pfam PF06737 Transglycosylase-like domain 39 114 4.5E-31 T 10-11-2016 IPR010618 Transglycosylase-like A4G23_RS25690 035c64f81628ab5ba370aba4978c1d61 455 Gene3D G3DSA:2.70.70.10 304 449 4.6E-45 T 10-11-2016 A4G23_RS25690 035c64f81628ab5ba370aba4978c1d61 455 SUPERFAMILY SSF51261 323 448 1.15E-46 T 10-11-2016 IPR011055 Duplicated hybrid motif A4G23_RS07420 8ef2c5a0e5874e2a17d9bd7f8659e2c0 915 Gene3D G3DSA:3.40.50.920 729 903 2.8E-69 T 10-11-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 A4G23_RS07420 8ef2c5a0e5874e2a17d9bd7f8659e2c0 915 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 150 307 1.3E-6 T 10-11-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A4G23_RS07420 8ef2c5a0e5874e2a17d9bd7f8659e2c0 915 SUPERFAMILY SSF52922 726 900 1.31E-53 T 10-11-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 A4G23_RS07420 8ef2c5a0e5874e2a17d9bd7f8659e2c0 915 SUPERFAMILY SSF52518 488 722 2.06E-83 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS07420 8ef2c5a0e5874e2a17d9bd7f8659e2c0 915 Gene3D G3DSA:3.40.50.970 70 483 4.0E-147 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS07420 8ef2c5a0e5874e2a17d9bd7f8659e2c0 915 Gene3D G3DSA:3.40.50.970 488 726 4.5E-108 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS07420 8ef2c5a0e5874e2a17d9bd7f8659e2c0 915 SUPERFAMILY SSF52518 70 482 1.8E-125 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS07420 8ef2c5a0e5874e2a17d9bd7f8659e2c0 915 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 19 908 0.0 T 10-11-2016 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 A4G23_RS07420 8ef2c5a0e5874e2a17d9bd7f8659e2c0 915 PIRSF PIRSF000156 10 910 0.0 T 10-11-2016 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 A4G23_RS19855 25dd06cd85419b226f02e7e583ab486f 680 Pfam PF01483 Proprotein convertase P-domain 600 679 3.5E-18 T 10-11-2016 IPR002884 Proprotein convertase, P GO:0004252|GO:0006508 A4G23_RS19855 25dd06cd85419b226f02e7e583ab486f 680 SUPERFAMILY SSF49785 573 679 3.53E-24 T 10-11-2016 IPR008979 Galactose-binding domain-like A4G23_RS19855 25dd06cd85419b226f02e7e583ab486f 680 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 388 399 2.9E-16 T 10-11-2016 IPR023612 Peptidase M4 GO:0004222|GO:0006508 A4G23_RS19855 25dd06cd85419b226f02e7e583ab486f 680 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 455 471 2.9E-16 T 10-11-2016 IPR023612 Peptidase M4 GO:0004222|GO:0006508 A4G23_RS19855 25dd06cd85419b226f02e7e583ab486f 680 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 331 351 2.9E-16 T 10-11-2016 IPR023612 Peptidase M4 GO:0004222|GO:0006508 A4G23_RS19855 25dd06cd85419b226f02e7e583ab486f 680 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 367 383 2.9E-16 T 10-11-2016 IPR023612 Peptidase M4 GO:0004222|GO:0006508 A4G23_RS19855 25dd06cd85419b226f02e7e583ab486f 680 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 89 134 1.6E-15 T 10-11-2016 IPR011096 FTP domain A4G23_RS19855 25dd06cd85419b226f02e7e583ab486f 680 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 379 553 1.6E-49 T 10-11-2016 IPR001570 Peptidase M4, C-terminal GO:0004222 A4G23_RS19855 25dd06cd85419b226f02e7e583ab486f 680 SUPERFAMILY SSF55486 226 554 1.79E-78 T 10-11-2016 A4G23_RS19855 25dd06cd85419b226f02e7e583ab486f 680 Gene3D G3DSA:2.60.120.260 580 679 1.4E-14 T 10-11-2016 IPR008979 Galactose-binding domain-like A4G23_RS19855 25dd06cd85419b226f02e7e583ab486f 680 Gene3D G3DSA:1.10.390.10 381 553 4.9E-49 T 10-11-2016 A4G23_RS19855 25dd06cd85419b226f02e7e583ab486f 680 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 230 376 9.0E-48 T 10-11-2016 IPR013856 Peptidase M4 domain GO:0004222 A4G23_RS19855 25dd06cd85419b226f02e7e583ab486f 680 Gene3D G3DSA:3.10.170.10 228 379 1.9E-44 T 10-11-2016 IPR013856 Peptidase M4 domain GO:0004222 A4G23_RS12000 8a87615782b3e9b79c16b7af892a5151 432 Gene3D G3DSA:3.40.50.1100 129 213 2.4E-27 T 10-11-2016 A4G23_RS12000 8a87615782b3e9b79c16b7af892a5151 432 TIGRFAM TIGR00260 thrC: threonine synthase 74 404 4.6E-80 T 10-11-2016 IPR004450 Threonine synthase-like A4G23_RS12000 8a87615782b3e9b79c16b7af892a5151 432 SUPERFAMILY SSF53686 22 418 1.83E-89 T 10-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4G23_RS12000 8a87615782b3e9b79c16b7af892a5151 432 Gene3D G3DSA:3.40.50.1100 214 409 3.4E-35 T 10-11-2016 A4G23_RS12000 8a87615782b3e9b79c16b7af892a5151 432 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 95 399 2.1E-64 T 10-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4G23_RS00895 e6c78567d0696099d4d10ea71b83d7cf 159 Hamap MF_00330 Cobalt transport protein CbiN [cbiN]. 1 117 39.442 T 10-11-2016 IPR003705 Cobalt transport protein CbiN GO:0006824|GO:0009236|GO:0015087|GO:0016020 A4G23_RS00895 e6c78567d0696099d4d10ea71b83d7cf 159 TIGRFAM TIGR01165 cbiN: cobalt transport protein 8 93 1.4E-38 T 10-11-2016 IPR003705 Cobalt transport protein CbiN GO:0006824|GO:0009236|GO:0015087|GO:0016020 A4G23_RS00895 e6c78567d0696099d4d10ea71b83d7cf 159 Pfam PF02553 Cobalt transport protein component CbiN 8 78 4.7E-29 T 10-11-2016 IPR003705 Cobalt transport protein CbiN GO:0006824|GO:0009236|GO:0015087|GO:0016020 A4G23_RS13995 604014961cc55c42140a96fecb7e5ef5 509 Gene3D G3DSA:3.40.630.10 250 475 2.1E-68 T 10-11-2016 A4G23_RS13995 604014961cc55c42140a96fecb7e5ef5 509 Gene3D G3DSA:3.40.630.10 39 102 2.1E-68 T 10-11-2016 A4G23_RS13995 604014961cc55c42140a96fecb7e5ef5 509 Pfam PF02225 PA domain 143 225 4.3E-12 T 10-11-2016 IPR003137 PA domain A4G23_RS13995 604014961cc55c42140a96fecb7e5ef5 509 Gene3D G3DSA:3.50.30.30 103 237 1.8E-31 T 10-11-2016 A4G23_RS13995 604014961cc55c42140a96fecb7e5ef5 509 SUPERFAMILY SSF52025 130 224 6.67E-13 T 10-11-2016 A4G23_RS13995 604014961cc55c42140a96fecb7e5ef5 509 Pfam PF04389 Peptidase family M28 251 469 8.1E-43 T 10-11-2016 IPR007484 Peptidase M28 A4G23_RS13995 604014961cc55c42140a96fecb7e5ef5 509 SUPERFAMILY SSF53187 235 475 4.96E-63 T 10-11-2016 A4G23_RS13995 604014961cc55c42140a96fecb7e5ef5 509 SUPERFAMILY SSF53187 41 92 4.96E-63 T 10-11-2016 A4G23_RS10600 dabc08817b01d7142033bb54f899638c 257 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 193 209 9.3E-12 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS10600 dabc08817b01d7142033bb54f899638c 257 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 209 221 9.3E-12 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS10600 dabc08817b01d7142033bb54f899638c 257 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 193 9.3E-12 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS10600 dabc08817b01d7142033bb54f899638c 257 SUPERFAMILY SSF52172 3 147 2.24E-17 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS10600 dabc08817b01d7142033bb54f899638c 257 SMART SM00421 176 233 2.1E-20 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS10600 dabc08817b01d7142033bb54f899638c 257 Pfam PF00072 Response regulator receiver domain 85 140 2.4E-5 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS10600 dabc08817b01d7142033bb54f899638c 257 Pfam PF00072 Response regulator receiver domain 6 71 3.7E-5 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS10600 dabc08817b01d7142033bb54f899638c 257 Gene3D G3DSA:3.40.50.2300 3 177 2.5E-37 T 10-11-2016 A4G23_RS10600 dabc08817b01d7142033bb54f899638c 257 SMART SM00448 4 140 8.0E-17 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS10600 dabc08817b01d7142033bb54f899638c 257 SUPERFAMILY SSF46894 166 238 2.65E-20 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS10600 dabc08817b01d7142033bb54f899638c 257 Gene3D G3DSA:1.10.10.10 178 238 1.4E-24 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS10600 dabc08817b01d7142033bb54f899638c 257 Pfam PF00196 Bacterial regulatory proteins, luxR family 178 233 9.1E-19 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS21085 07532f1f1b797ffc06676bce7506d66c 499 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 188 490 2.6E-81 T 10-11-2016 IPR005839 Methylthiotransferase GO:0016740|GO:0043412|GO:0051539 A4G23_RS21085 07532f1f1b797ffc06676bce7506d66c 499 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 5 493 61.002 T 10-11-2016 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 A4G23_RS21085 07532f1f1b797ffc06676bce7506d66c 499 Pfam PF04055 Radical SAM superfamily 199 369 3.1E-19 T 10-11-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 A4G23_RS21085 07532f1f1b797ffc06676bce7506d66c 499 Pfam PF00919 Uncharacterized protein family UPF0004 7 105 4.9E-31 T 10-11-2016 IPR013848 Methylthiotransferase, N-terminal GO:0003824|GO:0009451|GO:0051539 A4G23_RS21085 07532f1f1b797ffc06676bce7506d66c 499 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 7 490 2.8E-117 T 10-11-2016 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 A4G23_RS21085 07532f1f1b797ffc06676bce7506d66c 499 Gene3D G3DSA:3.80.30.20 194 422 6.9E-61 T 10-11-2016 IPR023404 Radical SAM, alpha/beta horseshoe A4G23_RS21085 07532f1f1b797ffc06676bce7506d66c 499 SUPERFAMILY SSF102114 183 416 3.92E-44 T 10-11-2016 A4G23_RS21085 07532f1f1b797ffc06676bce7506d66c 499 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 197 217 - T 10-11-2016 IPR020612 Methylthiotransferase, conserved site GO:0051539 A4G23_RS21085 07532f1f1b797ffc06676bce7506d66c 499 SMART SM00729 193 411 3.5E-40 T 10-11-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 A4G23_RS21085 07532f1f1b797ffc06676bce7506d66c 499 Gene3D G3DSA:2.40.50.140 426 496 2.4E-16 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS12610 17ce686e549c7b1a7ef818c5d47d4814 111 Pfam PF04149 Domain of unknown function (DUF397) 6 55 2.3E-11 T 10-11-2016 IPR007278 Domain of unknown function DUF397 A4G23_RS03265 5bc497dce26c5e0b783df3e264db18d0 254 Pfam PF00535 Glycosyl transferase family 2 19 180 5.4E-27 T 10-11-2016 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A4G23_RS03265 5bc497dce26c5e0b783df3e264db18d0 254 SUPERFAMILY SSF53448 19 229 6.26E-43 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS03265 5bc497dce26c5e0b783df3e264db18d0 254 Gene3D G3DSA:3.90.550.10 19 229 4.1E-23 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS15735 11028559f2a9987a54cf1292cdda8591 178 Gene3D G3DSA:3.30.530.20 6 136 6.4E-13 T 10-11-2016 IPR023393 START-like domain A4G23_RS15735 11028559f2a9987a54cf1292cdda8591 178 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 9 158 2.5E-14 T 10-11-2016 IPR019587 Polyketide cyclase/dehydrase A4G23_RS15735 11028559f2a9987a54cf1292cdda8591 178 SUPERFAMILY SSF55961 8 176 1.2E-19 T 10-11-2016 A4G23_RS06825 b58dc2ac9711c55ae473ec4e332ed806 1806 Pfam PF03714 Bacterial pullanase-associated domain 735 828 1.5E-24 T 10-11-2016 IPR005323 Bacterial pullanase-associated domain GO:0005975|GO:0030246 A4G23_RS06825 b58dc2ac9711c55ae473ec4e332ed806 1806 Pfam PF03714 Bacterial pullanase-associated domain 846 937 2.5E-19 T 10-11-2016 IPR005323 Bacterial pullanase-associated domain GO:0005975|GO:0030246 A4G23_RS06825 b58dc2ac9711c55ae473ec4e332ed806 1806 Pfam PF00128 Alpha amylase, catalytic domain 107 477 6.9E-94 T 10-11-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A4G23_RS06825 b58dc2ac9711c55ae473ec4e332ed806 1806 Gene3D G3DSA:3.20.20.80 1534 1651 1.7E-74 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS06825 b58dc2ac9711c55ae473ec4e332ed806 1806 Gene3D G3DSA:3.20.20.80 1187 1487 1.7E-74 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS06825 b58dc2ac9711c55ae473ec4e332ed806 1806 Gene3D G3DSA:3.20.20.80 1687 1712 1.7E-74 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS06825 b58dc2ac9711c55ae473ec4e332ed806 1806 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 546 621 0.0028 T 10-11-2016 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 A4G23_RS06825 b58dc2ac9711c55ae473ec4e332ed806 1806 SUPERFAMILY SSF51011 543 619 1.64E-6 T 10-11-2016 A4G23_RS06825 b58dc2ac9711c55ae473ec4e332ed806 1806 TIGRFAM TIGR02103 pullul_strch: alpha-1,6-glucosidases, pullulanase-type 951 1804 0.0 T 10-11-2016 IPR011839 Alpha-1,6-glucosidases, pullulanase-type GO:0005975|GO:0051060 A4G23_RS06825 b58dc2ac9711c55ae473ec4e332ed806 1806 SUPERFAMILY SSF51445 241 538 4.88E-93 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS06825 b58dc2ac9711c55ae473ec4e332ed806 1806 SUPERFAMILY SSF51445 58 195 4.88E-93 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS06825 b58dc2ac9711c55ae473ec4e332ed806 1806 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 1079 1157 1.2E-8 T 10-11-2016 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 A4G23_RS06825 b58dc2ac9711c55ae473ec4e332ed806 1806 SUPERFAMILY SSF49452 730 834 1.47E-30 T 10-11-2016 IPR013784 Carbohydrate-binding-like fold GO:0030246 A4G23_RS06825 b58dc2ac9711c55ae473ec4e332ed806 1806 SMART SM00642 69 529 1.7E-97 T 10-11-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A4G23_RS06825 b58dc2ac9711c55ae473ec4e332ed806 1806 Gene3D G3DSA:3.20.20.80 61 534 1.0E-97 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS06825 b58dc2ac9711c55ae473ec4e332ed806 1806 SUPERFAMILY SSF51011 1715 1803 1.99E-24 T 10-11-2016 A4G23_RS06825 b58dc2ac9711c55ae473ec4e332ed806 1806 Gene3D G3DSA:2.60.40.10 1080 1171 3.5E-15 T 10-11-2016 IPR013783 Immunoglobulin-like fold A4G23_RS06825 b58dc2ac9711c55ae473ec4e332ed806 1806 Gene3D G3DSA:2.60.40.1180 535 620 8.0E-14 T 10-11-2016 IPR013780 Glycosyl hydrolase, all-beta A4G23_RS06825 b58dc2ac9711c55ae473ec4e332ed806 1806 SUPERFAMILY SSF81296 1078 1173 1.48E-18 T 10-11-2016 IPR014756 Immunoglobulin E-set A4G23_RS06825 b58dc2ac9711c55ae473ec4e332ed806 1806 SUPERFAMILY SSF81296 946 1069 2.66E-31 T 10-11-2016 IPR014756 Immunoglobulin E-set A4G23_RS06825 b58dc2ac9711c55ae473ec4e332ed806 1806 SUPERFAMILY SSF51445 1169 1712 1.41E-118 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS06825 b58dc2ac9711c55ae473ec4e332ed806 1806 Pfam PF11852 Domain of unknown function (DUF3372) 1656 1803 1.7E-46 T 10-11-2016 IPR024561 Alpha-1,6-glucosidases, pullulanase-type, C-terminal A4G23_RS06825 b58dc2ac9711c55ae473ec4e332ed806 1806 SUPERFAMILY SSF49452 836 937 3.27E-31 T 10-11-2016 IPR013784 Carbohydrate-binding-like fold GO:0030246 A4G23_RS16515 44c9b0e7b83e7ff868b46e4abcad036b 724 Gene3D G3DSA:3.40.50.10320 240 318 4.5E-21 T 10-11-2016 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 A4G23_RS16515 44c9b0e7b83e7ff868b46e4abcad036b 724 Gene3D G3DSA:3.40.50.10320 92 196 4.5E-21 T 10-11-2016 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 A4G23_RS16515 44c9b0e7b83e7ff868b46e4abcad036b 724 SUPERFAMILY SSF102588 210 313 2.09E-19 T 10-11-2016 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 A4G23_RS16515 44c9b0e7b83e7ff868b46e4abcad036b 724 SUPERFAMILY SSF102588 92 166 2.09E-19 T 10-11-2016 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 A4G23_RS16515 44c9b0e7b83e7ff868b46e4abcad036b 724 SUPERFAMILY SSF89372 516 657 2.35E-11 T 10-11-2016 A4G23_RS16515 44c9b0e7b83e7ff868b46e4abcad036b 724 Pfam PF02585 GlcNAc-PI de-N-acetylase 94 309 1.1E-25 T 10-11-2016 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 A4G23_RS01165 004eeef2c1fab616203e7247770e1dd0 808 Gene3D G3DSA:3.30.450.20 281 371 8.0E-13 T 10-11-2016 A4G23_RS01165 004eeef2c1fab616203e7247770e1dd0 808 SMART SM00065 417 563 2.8E-5 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS01165 004eeef2c1fab616203e7247770e1dd0 808 Pfam PF13185 GAF domain 417 554 1.0E-12 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS01165 004eeef2c1fab616203e7247770e1dd0 808 Gene3D G3DSA:3.30.450.40 4 135 3.4E-5 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS01165 004eeef2c1fab616203e7247770e1dd0 808 Pfam PF08448 PAS fold 282 363 4.0E-9 T 10-11-2016 IPR013656 PAS fold-4 A4G23_RS01165 004eeef2c1fab616203e7247770e1dd0 808 Gene3D G3DSA:3.30.450.40 413 565 4.8E-13 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS01165 004eeef2c1fab616203e7247770e1dd0 808 SUPERFAMILY SSF81606 598 793 3.66E-6 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS01165 004eeef2c1fab616203e7247770e1dd0 808 SMART SM00331 581 795 1.5E-35 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS01165 004eeef2c1fab616203e7247770e1dd0 808 SUPERFAMILY SSF55785 281 362 1.74E-11 T 10-11-2016 IPR000014 PAS domain A4G23_RS01165 004eeef2c1fab616203e7247770e1dd0 808 SUPERFAMILY SSF55781 421 563 3.71E-16 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS01165 004eeef2c1fab616203e7247770e1dd0 808 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 611 795 1.4E-50 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS01165 004eeef2c1fab616203e7247770e1dd0 808 SMART SM00091 274 340 4.6E-4 T 10-11-2016 IPR000014 PAS domain A4G23_RS01165 004eeef2c1fab616203e7247770e1dd0 808 SUPERFAMILY SSF55781 11 139 2.84E-8 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS16085 98e06fea1b252901c034622c327f000c 217 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 65 76 - T 10-11-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4G23_RS16085 98e06fea1b252901c034622c327f000c 217 Pfam PF12838 4Fe-4S dicluster domain 64 124 5.1E-11 T 10-11-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4G23_RS16085 98e06fea1b252901c034622c327f000c 217 SUPERFAMILY SSF54862 38 155 2.05E-27 T 10-11-2016 A4G23_RS16085 98e06fea1b252901c034622c327f000c 217 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 12 154 28.552 T 10-11-2016 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16085 98e06fea1b252901c034622c327f000c 217 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 21 148 7.0E-44 T 10-11-2016 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16085 98e06fea1b252901c034622c327f000c 217 Gene3D G3DSA:1.10.1060.10 20 139 6.5E-20 T 10-11-2016 A4G23_RS16085 98e06fea1b252901c034622c327f000c 217 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 110 121 - T 10-11-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4G23_RS07945 e9a02d7807fe234bceb24feb74985304 410 SUPERFAMILY SSF102114 19 408 1.2E-106 T 10-11-2016 A4G23_RS07945 e9a02d7807fe234bceb24feb74985304 410 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 32 362 3.0E-68 T 10-11-2016 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 A4G23_RS07945 e9a02d7807fe234bceb24feb74985304 410 SMART SM00729 29 259 1.1E-60 T 10-11-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 A4G23_RS07945 e9a02d7807fe234bceb24feb74985304 410 Pfam PF04055 Radical SAM superfamily 35 213 3.3E-21 T 10-11-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 A4G23_RS07945 e9a02d7807fe234bceb24feb74985304 410 Gene3D G3DSA:3.80.30.20 32 273 6.2E-34 T 10-11-2016 IPR023404 Radical SAM, alpha/beta horseshoe A4G23_RS15170 6e183fd89bb19e1ce8ef059d7ea7d6fe 101 Pfam PF00253 Ribosomal protein S14p/S29e 48 100 1.3E-23 T 10-11-2016 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS15170 6e183fd89bb19e1ce8ef059d7ea7d6fe 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 26.928 T 10-11-2016 IPR023036 Ribosomal protein S14, bacterial/plastid A4G23_RS15170 6e183fd89bb19e1ce8ef059d7ea7d6fe 101 Gene3D G3DSA:4.10.830.10 43 101 5.3E-27 T 10-11-2016 A4G23_RS15170 6e183fd89bb19e1ce8ef059d7ea7d6fe 101 SUPERFAMILY SSF57716 2 101 1.28E-32 T 10-11-2016 A4G23_RS04425 5f36e305fe62149d921ab587212bb3b2 350 TIGRFAM TIGR03559 F420_Rv3520c: probable F420-dependent oxidoreductase, Rv3520c family 2 322 5.7E-117 T 10-11-2016 IPR019951 F420-dependent oxidoreductase-predicted, Rv3520c A4G23_RS04425 5f36e305fe62149d921ab587212bb3b2 350 SUPERFAMILY SSF51679 1 337 1.14E-71 T 10-11-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4G23_RS04425 5f36e305fe62149d921ab587212bb3b2 350 Gene3D G3DSA:3.20.20.30 1 335 6.1E-76 T 10-11-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4G23_RS04425 5f36e305fe62149d921ab587212bb3b2 350 Pfam PF00296 Luciferase-like monooxygenase 17 318 6.2E-80 T 10-11-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4G23_RS06055 5216e11617a8300d830d073236b46327 213 SUPERFAMILY SSF52317 4 211 1.92E-53 T 10-11-2016 IPR029062 Class I glutamine amidotransferase-like A4G23_RS06055 5216e11617a8300d830d073236b46327 213 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 6 212 31.406 T 10-11-2016 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 A4G23_RS06055 5216e11617a8300d830d073236b46327 213 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 7 211 9.5E-62 T 10-11-2016 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 A4G23_RS06055 5216e11617a8300d830d073236b46327 213 Gene3D G3DSA:3.40.50.880 5 211 6.0E-75 T 10-11-2016 IPR029062 Class I glutamine amidotransferase-like A4G23_RS06055 5216e11617a8300d830d073236b46327 213 PIRSF PIRSF000495 5 213 9.4E-66 T 10-11-2016 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 A4G23_RS06055 5216e11617a8300d830d073236b46327 213 Pfam PF00117 Glutamine amidotransferase class-I 9 208 2.0E-18 T 10-11-2016 IPR017926 Glutamine amidotransferase A4G23_RS14240 e594e6a256accea8972262fa8f4fc509 204 Gene3D G3DSA:2.60.120.10 110 188 5.8E-26 T 10-11-2016 IPR014710 RmlC-like jelly roll fold A4G23_RS14240 e594e6a256accea8972262fa8f4fc509 204 Pfam PF07883 Cupin domain 114 182 1.3E-12 T 10-11-2016 IPR013096 Cupin 2, conserved barrel A4G23_RS14240 e594e6a256accea8972262fa8f4fc509 204 SUPERFAMILY SSF47413 9 74 7.88E-14 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS14240 e594e6a256accea8972262fa8f4fc509 204 SUPERFAMILY SSF51182 54 184 8.91E-23 T 10-11-2016 IPR011051 RmlC-like cupin domain A4G23_RS14240 e594e6a256accea8972262fa8f4fc509 204 Gene3D G3DSA:1.10.260.40 10 109 4.8E-18 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS14240 e594e6a256accea8972262fa8f4fc509 204 Pfam PF01381 Helix-turn-helix 15 67 4.0E-10 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS14240 e594e6a256accea8972262fa8f4fc509 204 SMART SM00530 14 69 1.8E-11 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS20650 b1879a7ee12e0a6c365541a300e8bdf8 163 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 18 34 1.1E-9 T 10-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 A4G23_RS20650 b1879a7ee12e0a6c365541a300e8bdf8 163 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 34 45 1.1E-9 T 10-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 A4G23_RS20650 b1879a7ee12e0a6c365541a300e8bdf8 163 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 45 64 1.1E-9 T 10-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 A4G23_RS20650 b1879a7ee12e0a6c365541a300e8bdf8 163 Pfam PF01037 Lrp/AsnC ligand binding domain 84 152 4.9E-16 T 10-11-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A4G23_RS20650 b1879a7ee12e0a6c365541a300e8bdf8 163 Gene3D G3DSA:3.30.70.920 81 152 3.0E-17 T 10-11-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A4G23_RS20650 b1879a7ee12e0a6c365541a300e8bdf8 163 Pfam PF13404 AsnC-type helix-turn-helix domain 18 58 7.1E-15 T 10-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 A4G23_RS20650 b1879a7ee12e0a6c365541a300e8bdf8 163 SUPERFAMILY SSF54909 80 160 1.22E-15 T 10-11-2016 IPR011008 Dimeric alpha-beta barrel A4G23_RS20650 b1879a7ee12e0a6c365541a300e8bdf8 163 Gene3D G3DSA:1.10.10.10 17 65 3.3E-15 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS20650 b1879a7ee12e0a6c365541a300e8bdf8 163 SMART SM00344 18 122 2.5E-33 T 10-11-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A4G23_RS20650 b1879a7ee12e0a6c365541a300e8bdf8 163 SUPERFAMILY SSF46785 18 70 5.35E-9 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS26100 bc76101874e2e99fea26368b8006c8c7 323 SUPERFAMILY SSF53474 3 313 1.97E-36 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS26100 bc76101874e2e99fea26368b8006c8c7 323 Gene3D G3DSA:3.40.50.1820 2 321 5.2E-98 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS26100 bc76101874e2e99fea26368b8006c8c7 323 Pfam PF05448 Acetyl xylan esterase (AXE1) 1 318 1.6E-120 T 10-11-2016 IPR008391 Acetyl xylan esterase A4G23_RS06040 55cf30cdf87553d72d886b771d5c44dd 256 Gene3D G3DSA:3.20.20.70 6 256 1.0E-103 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS06040 55cf30cdf87553d72d886b771d5c44dd 256 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 2 256 47.876 T 10-11-2016 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 A4G23_RS06040 55cf30cdf87553d72d886b771d5c44dd 256 SUPERFAMILY SSF51366 4 256 2.83E-83 T 10-11-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 A4G23_RS06040 55cf30cdf87553d72d886b771d5c44dd 256 Pfam PF00977 Histidine biosynthesis protein 6 239 7.5E-88 T 10-11-2016 IPR006062 Histidine biosynthesis GO:0000105 A4G23_RS06040 55cf30cdf87553d72d886b771d5c44dd 256 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 3 256 4.3E-109 T 10-11-2016 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 A4G23_RS10705 0e4437c8ea0b44e9837ed270a9f01c4f 113 Pfam PF04686 Streptomyces sporulation and cell division protein, SsgA 19 106 2.1E-19 T 10-11-2016 IPR006776 Sporulation-specific cell division protein SsgB GO:0051301 A4G23_RS06685 ad5fd9a74d82a7964e352cc9a1d1f3dd 506 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 20 148 7.4E-26 T 10-11-2016 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 A4G23_RS06685 ad5fd9a74d82a7964e352cc9a1d1f3dd 506 Gene3D G3DSA:3.40.630.10 181 501 8.2E-132 T 10-11-2016 A4G23_RS06685 ad5fd9a74d82a7964e352cc9a1d1f3dd 506 Gene3D G3DSA:3.40.220.10 16 180 1.9E-40 T 10-11-2016 A4G23_RS06685 ad5fd9a74d82a7964e352cc9a1d1f3dd 506 SUPERFAMILY SSF52949 17 163 4.41E-26 T 10-11-2016 A4G23_RS06685 ad5fd9a74d82a7964e352cc9a1d1f3dd 506 PRINTS PR00481 Cytosol aminopeptidase signature 372 387 2.8E-50 T 10-11-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A4G23_RS06685 ad5fd9a74d82a7964e352cc9a1d1f3dd 506 PRINTS PR00481 Cytosol aminopeptidase signature 285 306 2.8E-50 T 10-11-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A4G23_RS06685 ad5fd9a74d82a7964e352cc9a1d1f3dd 506 PRINTS PR00481 Cytosol aminopeptidase signature 322 343 2.8E-50 T 10-11-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A4G23_RS06685 ad5fd9a74d82a7964e352cc9a1d1f3dd 506 PRINTS PR00481 Cytosol aminopeptidase signature 344 364 2.8E-50 T 10-11-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A4G23_RS06685 ad5fd9a74d82a7964e352cc9a1d1f3dd 506 PRINTS PR00481 Cytosol aminopeptidase signature 263 280 2.8E-50 T 10-11-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A4G23_RS06685 ad5fd9a74d82a7964e352cc9a1d1f3dd 506 SUPERFAMILY SSF53187 182 499 2.3E-113 T 10-11-2016 A4G23_RS06685 ad5fd9a74d82a7964e352cc9a1d1f3dd 506 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 348 355 - T 10-11-2016 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 A4G23_RS06685 ad5fd9a74d82a7964e352cc9a1d1f3dd 506 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 4 502 34.814 T 10-11-2016 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 A4G23_RS06685 ad5fd9a74d82a7964e352cc9a1d1f3dd 506 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 188 494 8.7E-117 T 10-11-2016 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 A4G23_RS02400 3ed9394653328dc7cb4a8cf32d36a3a9 621 Gene3D G3DSA:1.20.1560.10 22 327 1.8E-35 T 10-11-2016 A4G23_RS02400 3ed9394653328dc7cb4a8cf32d36a3a9 621 ProSitePatterns PS00211 ABC transporters family signature. 498 512 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS02400 3ed9394653328dc7cb4a8cf32d36a3a9 621 Pfam PF00005 ABC transporter 479 526 6.9E-11 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS02400 3ed9394653328dc7cb4a8cf32d36a3a9 621 Pfam PF00664 ABC transporter transmembrane region 72 293 3.5E-19 T 10-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A4G23_RS02400 3ed9394653328dc7cb4a8cf32d36a3a9 621 Gene3D G3DSA:3.40.50.300 415 604 8.7E-37 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS02400 3ed9394653328dc7cb4a8cf32d36a3a9 621 SUPERFAMILY SSF52540 411 593 1.65E-34 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS02400 3ed9394653328dc7cb4a8cf32d36a3a9 621 SUPERFAMILY SSF90123 21 327 6.02E-43 T 10-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A4G23_RS15740 884fed9865f5cb2a1ef54c11b45fd826 89 Pfam PF08962 Domain of unknown function (DUF1876) 6 85 2.0E-30 T 10-11-2016 IPR015057 Protein of unknown function DUF1876 A4G23_RS15740 884fed9865f5cb2a1ef54c11b45fd826 89 ProDom PD280340 RV1738/MT1780 MB2665C MB1767 SCO3163 RV2632C/MT2708 2 78 7.0E-25 T 10-11-2016 IPR015057 Protein of unknown function DUF1876 A4G23_RS15740 884fed9865f5cb2a1ef54c11b45fd826 89 SUPERFAMILY SSF143212 1 83 9.02E-27 T 10-11-2016 A4G23_RS09310 877c9ab94d58d0486313964f9773b91c 442 Pfam PF00480 ROK family 271 349 1.8E-16 T 10-11-2016 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A4G23_RS09310 877c9ab94d58d0486313964f9773b91c 442 Gene3D G3DSA:3.30.420.40 306 350 6.6E-20 T 10-11-2016 A4G23_RS09310 877c9ab94d58d0486313964f9773b91c 442 Gene3D G3DSA:1.10.10.10 9 78 6.3E-18 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS09310 877c9ab94d58d0486313964f9773b91c 442 SUPERFAMILY SSF53067 291 436 7.6E-26 T 10-11-2016 A4G23_RS09310 877c9ab94d58d0486313964f9773b91c 442 Gene3D G3DSA:3.30.420.40 353 409 1.6E-6 T 10-11-2016 A4G23_RS09310 877c9ab94d58d0486313964f9773b91c 442 SUPERFAMILY SSF46785 9 73 2.48E-10 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS09310 877c9ab94d58d0486313964f9773b91c 442 Gene3D G3DSA:3.30.420.40 268 305 1.1E-39 T 10-11-2016 A4G23_RS09310 877c9ab94d58d0486313964f9773b91c 442 Gene3D G3DSA:3.30.420.40 79 179 1.1E-39 T 10-11-2016 A4G23_RS09310 877c9ab94d58d0486313964f9773b91c 442 SUPERFAMILY SSF53067 79 179 5.31E-14 T 10-11-2016 A4G23_RS09310 877c9ab94d58d0486313964f9773b91c 442 Pfam PF12802 MarR family 8 59 6.7E-8 T 10-11-2016 A4G23_RS15900 de7059994819b1faacab754fde1c95b2 151 SUPERFAMILY SSF46785 1 60 1.25E-15 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS15900 de7059994819b1faacab754fde1c95b2 151 SUPERFAMILY SSF54909 61 143 2.15E-18 T 10-11-2016 IPR011008 Dimeric alpha-beta barrel A4G23_RS15900 de7059994819b1faacab754fde1c95b2 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 8.1E-14 T 10-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 A4G23_RS15900 de7059994819b1faacab754fde1c95b2 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 8.1E-14 T 10-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 A4G23_RS15900 de7059994819b1faacab754fde1c95b2 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 8.1E-14 T 10-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 A4G23_RS15900 de7059994819b1faacab754fde1c95b2 151 SMART SM00344 1 108 8.7E-39 T 10-11-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A4G23_RS15900 de7059994819b1faacab754fde1c95b2 151 ProSitePatterns PS00519 AsnC-type HTH domain signature. 19 45 - T 10-11-2016 IPR019885 Transcription regulator HTH, AsnC-type, conserved site A4G23_RS15900 de7059994819b1faacab754fde1c95b2 151 Pfam PF13404 AsnC-type helix-turn-helix domain 1 42 9.3E-17 T 10-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 A4G23_RS15900 de7059994819b1faacab754fde1c95b2 151 Gene3D G3DSA:1.10.10.10 1 52 2.9E-21 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS15900 de7059994819b1faacab754fde1c95b2 151 Pfam PF01037 Lrp/AsnC ligand binding domain 67 138 2.1E-19 T 10-11-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A4G23_RS15900 de7059994819b1faacab754fde1c95b2 151 Gene3D G3DSA:3.30.70.920 54 144 2.2E-24 T 10-11-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A4G23_RS12865 96db287e01d57aebc783b4674851c883 360 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 30 139 6.1E-24 T 10-11-2016 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 A4G23_RS12865 96db287e01d57aebc783b4674851c883 360 Gene3D G3DSA:3.40.192.10 15 155 5.7E-63 T 10-11-2016 A4G23_RS12865 96db287e01d57aebc783b4674851c883 360 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 297 308 2.8E-20 T 10-11-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 A4G23_RS12865 96db287e01d57aebc783b4674851c883 360 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 74 88 2.8E-20 T 10-11-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 A4G23_RS12865 96db287e01d57aebc783b4674851c883 360 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 140 162 2.8E-20 T 10-11-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 A4G23_RS12865 96db287e01d57aebc783b4674851c883 360 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 184 204 2.8E-20 T 10-11-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 A4G23_RS12865 96db287e01d57aebc783b4674851c883 360 SUPERFAMILY SSF51735 149 359 3.04E-46 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS12865 96db287e01d57aebc783b4674851c883 360 Gene3D G3DSA:3.40.50.720 156 347 8.5E-50 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS12865 96db287e01d57aebc783b4674851c883 360 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 82 95 - T 10-11-2016 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-70614 A4G23_RS12865 96db287e01d57aebc783b4674851c883 360 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 219 307 7.4E-8 T 10-11-2016 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 A4G23_RS12865 96db287e01d57aebc783b4674851c883 360 PIRSF PIRSF000188 9 360 4.8E-143 T 10-11-2016 IPR016211 Glutamate/phenylalanine/leucine/valine dehydrogenase, bacterial/archaeal GO:0016639|GO:0055114 A4G23_RS12865 96db287e01d57aebc783b4674851c883 360 SMART SM00839 152 359 1.2E-45 T 10-11-2016 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 A4G23_RS12865 96db287e01d57aebc783b4674851c883 360 SUPERFAMILY SSF53223 19 152 1.98E-43 T 10-11-2016 A4G23_RS16355 f3ed6650feeac9d8cfe249763be9cc75 333 SUPERFAMILY SSF89392 126 300 5.49E-10 T 10-11-2016 IPR029046 Lipoprotein localisation LolA/LolB/LppX A4G23_RS09745 8aa78061a388ea954683fe0219625c23 370 SMART SM00937 84 194 2.1E-44 T 10-11-2016 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 A4G23_RS09745 8aa78061a388ea954683fe0219625c23 370 Pfam PF00472 RF-1 domain 228 336 9.0E-38 T 10-11-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 A4G23_RS09745 8aa78061a388ea954683fe0219625c23 370 Hamap MF_00094 Peptide chain release factor 2 [prfB]. 2 364 38.092 T 10-11-2016 IPR020853 Peptide chain release factor 2, bacterial GO:0005737|GO:0006415|GO:0016149 A4G23_RS09745 8aa78061a388ea954683fe0219625c23 370 SUPERFAMILY SSF75620 30 366 4.58E-121 T 10-11-2016 A4G23_RS09745 8aa78061a388ea954683fe0219625c23 370 Gene3D G3DSA:3.30.160.20 227 305 2.6E-34 T 10-11-2016 IPR014720 Double-stranded RNA-binding domain A4G23_RS09745 8aa78061a388ea954683fe0219625c23 370 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 3 363 7.9E-157 T 10-11-2016 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 A4G23_RS09745 8aa78061a388ea954683fe0219625c23 370 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 244 260 - T 10-11-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 A4G23_RS09745 8aa78061a388ea954683fe0219625c23 370 Gene3D G3DSA:1.20.58.410 4 115 1.8E-33 T 10-11-2016 A4G23_RS09745 8aa78061a388ea954683fe0219625c23 370 Pfam PF03462 PCRF domain 30 219 5.5E-55 T 10-11-2016 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 A4G23_RS04215 c099cf98d013929740f3fd3ddab1c0a1 279 Gene3D G3DSA:3.40.50.80 133 276 4.6E-54 T 10-11-2016 A4G23_RS04215 c099cf98d013929740f3fd3ddab1c0a1 279 Pfam PF08021 Siderophore-interacting FAD-binding domain 16 130 1.2E-37 T 10-11-2016 IPR013113 FAD-binding 9, siderophore-interacting A4G23_RS04215 c099cf98d013929740f3fd3ddab1c0a1 279 Gene3D G3DSA:2.40.30.10 7 130 3.1E-35 T 10-11-2016 A4G23_RS04215 c099cf98d013929740f3fd3ddab1c0a1 279 SUPERFAMILY SSF63380 8 136 1.02E-11 T 10-11-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 A4G23_RS04215 c099cf98d013929740f3fd3ddab1c0a1 279 Pfam PF04954 Siderophore-interacting protein 138 255 7.4E-40 T 10-11-2016 IPR007037 Siderophore-interacting protein A4G23_RS14880 00234138857bdf76c7943fa68f3c1cb9 656 Gene3D G3DSA:3.40.50.980 81 266 6.3E-43 T 10-11-2016 A4G23_RS14880 00234138857bdf76c7943fa68f3c1cb9 656 Pfam PF13193 AMP-binding enzyme C-terminal domain 532 615 5.8E-26 T 10-11-2016 IPR025110 AMP-binding enzyme C-terminal domain A4G23_RS14880 00234138857bdf76c7943fa68f3c1cb9 656 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 31 83 1.1E-20 T 10-11-2016 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118 A4G23_RS14880 00234138857bdf76c7943fa68f3c1cb9 656 Gene3D G3DSA:2.30.38.10 440 516 9.5E-8 T 10-11-2016 A4G23_RS14880 00234138857bdf76c7943fa68f3c1cb9 656 Gene3D G3DSA:3.40.50.980 267 425 2.5E-28 T 10-11-2016 A4G23_RS14880 00234138857bdf76c7943fa68f3c1cb9 656 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 26 646 6.6E-297 T 10-11-2016 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118|Reactome: R-HSA-71384 A4G23_RS14880 00234138857bdf76c7943fa68f3c1cb9 656 Pfam PF00501 AMP-binding enzyme 91 523 1.9E-92 T 10-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A4G23_RS14880 00234138857bdf76c7943fa68f3c1cb9 656 Gene3D G3DSA:3.30.300.30 523 629 1.6E-28 T 10-11-2016 A4G23_RS14880 00234138857bdf76c7943fa68f3c1cb9 656 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 11 649 51.734 T 10-11-2016 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118|Reactome: R-HSA-71384 A4G23_RS14880 00234138857bdf76c7943fa68f3c1cb9 656 SUPERFAMILY SSF56801 31 646 6.8E-177 T 10-11-2016 A4G23_RS14880 00234138857bdf76c7943fa68f3c1cb9 656 ProSitePatterns PS00455 Putative AMP-binding domain signature. 261 272 - T 10-11-2016 IPR020845 AMP-binding, conserved site A4G23_RS18725 4e7ae2f283249e31b91cd4150b6b6dff 709 TIGRFAM TIGR01581 Mo_ABC_porter: NifC-like ABC-type porter 31 252 1.2E-66 T 10-11-2016 IPR006469 NifC-like ABC-type porter GO:0005215|GO:0006810|GO:0016020 A4G23_RS18725 4e7ae2f283249e31b91cd4150b6b6dff 709 Gene3D G3DSA:1.10.3720.10 6 253 7.7E-40 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS18725 4e7ae2f283249e31b91cd4150b6b6dff 709 SMART SM00382 380 564 2.5E-15 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS18725 4e7ae2f283249e31b91cd4150b6b6dff 709 Pfam PF00005 ABC transporter 374 514 2.4E-28 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS18725 4e7ae2f283249e31b91cd4150b6b6dff 709 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 53 254 3.0E-61 T 10-11-2016 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 A4G23_RS18725 4e7ae2f283249e31b91cd4150b6b6dff 709 Gene3D G3DSA:3.40.50.300 373 587 3.0E-62 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS18725 4e7ae2f283249e31b91cd4150b6b6dff 709 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 69 250 7.3E-12 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS18725 4e7ae2f283249e31b91cd4150b6b6dff 709 Pfam PF03459 TOBE domain 642 705 5.4E-11 T 10-11-2016 IPR005116 Transport-associated OB, type 1 A4G23_RS18725 4e7ae2f283249e31b91cd4150b6b6dff 709 SUPERFAMILY SSF161098 6 254 2.49E-47 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS18725 4e7ae2f283249e31b91cd4150b6b6dff 709 Gene3D G3DSA:2.40.50.100 640 707 1.1E-14 T 10-11-2016 A4G23_RS18725 4e7ae2f283249e31b91cd4150b6b6dff 709 SUPERFAMILY SSF50331 589 706 7.02E-20 T 10-11-2016 IPR008995 Molybdate/tungstate binding, C-terminal A4G23_RS18725 4e7ae2f283249e31b91cd4150b6b6dff 709 ProSitePatterns PS00211 ABC transporters family signature. 487 501 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS18725 4e7ae2f283249e31b91cd4150b6b6dff 709 SUPERFAMILY SSF52540 373 590 3.17E-60 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS03275 bf4f45f715b7b8bea829cb2decda52ff 146 SUPERFAMILY SSF46785 1 60 1.28E-17 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS03275 bf4f45f715b7b8bea829cb2decda52ff 146 Gene3D G3DSA:3.30.70.920 54 133 2.0E-23 T 10-11-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A4G23_RS03275 bf4f45f715b7b8bea829cb2decda52ff 146 ProSitePatterns PS00519 AsnC-type HTH domain signature. 19 45 - T 10-11-2016 IPR019885 Transcription regulator HTH, AsnC-type, conserved site A4G23_RS03275 bf4f45f715b7b8bea829cb2decda52ff 146 Pfam PF13404 AsnC-type helix-turn-helix domain 1 42 8.9E-17 T 10-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 A4G23_RS03275 bf4f45f715b7b8bea829cb2decda52ff 146 Gene3D G3DSA:1.10.10.10 3 53 8.5E-23 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS03275 bf4f45f715b7b8bea829cb2decda52ff 146 Pfam PF01037 Lrp/AsnC ligand binding domain 67 137 2.4E-14 T 10-11-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A4G23_RS03275 bf4f45f715b7b8bea829cb2decda52ff 146 SUPERFAMILY SSF54909 61 144 1.47E-14 T 10-11-2016 IPR011008 Dimeric alpha-beta barrel A4G23_RS03275 bf4f45f715b7b8bea829cb2decda52ff 146 SMART SM00344 1 108 6.6E-44 T 10-11-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A4G23_RS03275 bf4f45f715b7b8bea829cb2decda52ff 146 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 4.4E-16 T 10-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 A4G23_RS03275 bf4f45f715b7b8bea829cb2decda52ff 146 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 4.4E-16 T 10-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 A4G23_RS03275 bf4f45f715b7b8bea829cb2decda52ff 146 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 4.4E-16 T 10-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 A4G23_RS23495 f6f409e79d39471f8a2f4a908ecaeb87 713 Gene3D G3DSA:3.30.365.10 174 273 2.6E-35 T 10-11-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 A4G23_RS23495 f6f409e79d39471f8a2f4a908ecaeb87 713 SUPERFAMILY SSF54665 8 124 8.77E-26 T 10-11-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead A4G23_RS23495 f6f409e79d39471f8a2f4a908ecaeb87 713 Gene3D G3DSA:3.90.1170.50 9 124 3.0E-23 T 10-11-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead A4G23_RS23495 f6f409e79d39471f8a2f4a908ecaeb87 713 Gene3D G3DSA:3.30.365.10 141 173 1.1E-4 T 10-11-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 A4G23_RS23495 f6f409e79d39471f8a2f4a908ecaeb87 713 Gene3D G3DSA:3.30.365.10 281 309 1.1E-4 T 10-11-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 A4G23_RS23495 f6f409e79d39471f8a2f4a908ecaeb87 713 SMART SM01008 24 134 3.4E-18 T 10-11-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead A4G23_RS23495 f6f409e79d39471f8a2f4a908ecaeb87 713 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 24 124 8.1E-10 T 10-11-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead A4G23_RS23495 f6f409e79d39471f8a2f4a908ecaeb87 713 Gene3D G3DSA:3.30.365.10 441 537 1.0E-24 T 10-11-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 A4G23_RS23495 f6f409e79d39471f8a2f4a908ecaeb87 713 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 540 645 1.2E-25 T 10-11-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 A4G23_RS23495 f6f409e79d39471f8a2f4a908ecaeb87 713 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 160 534 2.5E-89 T 10-11-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 A4G23_RS23495 f6f409e79d39471f8a2f4a908ecaeb87 713 Gene3D G3DSA:3.30.365.10 354 440 1.6E-59 T 10-11-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 A4G23_RS23495 f6f409e79d39471f8a2f4a908ecaeb87 713 Gene3D G3DSA:3.30.365.10 559 705 1.6E-59 T 10-11-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 A4G23_RS23495 f6f409e79d39471f8a2f4a908ecaeb87 713 SUPERFAMILY SSF56003 143 705 4.97E-159 T 10-11-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 A4G23_RS03340 755374ffb00921a88437a3b24d82b16e 654 SMART SM00382 404 545 1.3E-9 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS03340 755374ffb00921a88437a3b24d82b16e 654 Gene3D G3DSA:3.40.50.300 368 542 3.5E-21 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS03340 755374ffb00921a88437a3b24d82b16e 654 PRINTS PR00819 CbxX/CfqX superfamily signature 492 504 1.7E-50 T 10-11-2016 IPR000641 CbxX/CfqX GO:0005524 A4G23_RS03340 755374ffb00921a88437a3b24d82b16e 654 PRINTS PR00819 CbxX/CfqX superfamily signature 530 549 1.7E-50 T 10-11-2016 IPR000641 CbxX/CfqX GO:0005524 A4G23_RS03340 755374ffb00921a88437a3b24d82b16e 654 PRINTS PR00819 CbxX/CfqX superfamily signature 459 478 1.7E-50 T 10-11-2016 IPR000641 CbxX/CfqX GO:0005524 A4G23_RS03340 755374ffb00921a88437a3b24d82b16e 654 PRINTS PR00819 CbxX/CfqX superfamily signature 590 602 1.7E-50 T 10-11-2016 IPR000641 CbxX/CfqX GO:0005524 A4G23_RS03340 755374ffb00921a88437a3b24d82b16e 654 PRINTS PR00819 CbxX/CfqX superfamily signature 367 381 1.7E-50 T 10-11-2016 IPR000641 CbxX/CfqX GO:0005524 A4G23_RS03340 755374ffb00921a88437a3b24d82b16e 654 PRINTS PR00819 CbxX/CfqX superfamily signature 407 422 1.7E-50 T 10-11-2016 IPR000641 CbxX/CfqX GO:0005524 A4G23_RS03340 755374ffb00921a88437a3b24d82b16e 654 PRINTS PR00819 CbxX/CfqX superfamily signature 513 530 1.7E-50 T 10-11-2016 IPR000641 CbxX/CfqX GO:0005524 A4G23_RS03340 755374ffb00921a88437a3b24d82b16e 654 PRINTS PR00819 CbxX/CfqX superfamily signature 445 459 1.7E-50 T 10-11-2016 IPR000641 CbxX/CfqX GO:0005524 A4G23_RS03340 755374ffb00921a88437a3b24d82b16e 654 Gene3D G3DSA:1.25.40.10 176 252 1.5E-10 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS03340 755374ffb00921a88437a3b24d82b16e 654 Gene3D G3DSA:1.25.40.10 17 52 1.5E-10 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS03340 755374ffb00921a88437a3b24d82b16e 654 SUPERFAMILY SSF52540 368 612 1.67E-31 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS03340 755374ffb00921a88437a3b24d82b16e 654 Pfam PF13432 Tetratricopeptide repeat 19 52 0.0062 T 10-11-2016 A4G23_RS03340 755374ffb00921a88437a3b24d82b16e 654 Pfam PF13432 Tetratricopeptide repeat 177 234 0.0015 T 10-11-2016 A4G23_RS03340 755374ffb00921a88437a3b24d82b16e 654 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 409 542 8.7E-14 T 10-11-2016 IPR003959 ATPase, AAA-type, core GO:0005524 A4G23_RS03340 755374ffb00921a88437a3b24d82b16e 654 SUPERFAMILY SSF48452 16 51 4.0E-8 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS03340 755374ffb00921a88437a3b24d82b16e 654 SUPERFAMILY SSF48452 175 241 4.0E-8 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS05530 c4cc5a683691f2a2ce5157667ef41005 298 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 49 66 - T 10-11-2016 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4G23_RS05530 c4cc5a683691f2a2ce5157667ef41005 298 Pfam PF00701 Dihydrodipicolinate synthetase family 12 288 1.0E-66 T 10-11-2016 IPR002220 DapA-like GO:0008152|GO:0016829 A4G23_RS05530 c4cc5a683691f2a2ce5157667ef41005 298 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 11 293 47.834 T 10-11-2016 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4G23_RS05530 c4cc5a683691f2a2ce5157667ef41005 298 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 144 174 - T 10-11-2016 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4G23_RS05530 c4cc5a683691f2a2ce5157667ef41005 298 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 16 261 1.2E-63 T 10-11-2016 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4G23_RS05530 c4cc5a683691f2a2ce5157667ef41005 298 SMART SM01130 11 295 2.9E-96 T 10-11-2016 IPR002220 DapA-like GO:0008152|GO:0016829 A4G23_RS05530 c4cc5a683691f2a2ce5157667ef41005 298 SUPERFAMILY SSF51569 10 294 5.34E-80 T 10-11-2016 A4G23_RS05530 c4cc5a683691f2a2ce5157667ef41005 298 Gene3D G3DSA:3.20.20.70 11 294 9.5E-90 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS05530 c4cc5a683691f2a2ce5157667ef41005 298 PRINTS PR00146 Dihydrodipicolinate synthase signature 82 100 1.0E-26 T 10-11-2016 IPR002220 DapA-like GO:0008152|GO:0016829 A4G23_RS05530 c4cc5a683691f2a2ce5157667ef41005 298 PRINTS PR00146 Dihydrodipicolinate synthase signature 114 130 1.0E-26 T 10-11-2016 IPR002220 DapA-like GO:0008152|GO:0016829 A4G23_RS05530 c4cc5a683691f2a2ce5157667ef41005 298 PRINTS PR00146 Dihydrodipicolinate synthase signature 139 156 1.0E-26 T 10-11-2016 IPR002220 DapA-like GO:0008152|GO:0016829 A4G23_RS05530 c4cc5a683691f2a2ce5157667ef41005 298 PRINTS PR00146 Dihydrodipicolinate synthase signature 46 67 1.0E-26 T 10-11-2016 IPR002220 DapA-like GO:0008152|GO:0016829 A4G23_RS05530 c4cc5a683691f2a2ce5157667ef41005 298 PIRSF PIRSF001365 10 298 1.2E-75 T 10-11-2016 IPR002220 DapA-like GO:0008152|GO:0016829 A4G23_RS13250 9705f1720de8a3cedba37a281557ff40 197 Gene3D G3DSA:1.10.357.10 60 195 4.8E-44 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS13250 9705f1720de8a3cedba37a281557ff40 197 Gene3D G3DSA:1.10.10.60 2 59 5.9E-21 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS13250 9705f1720de8a3cedba37a281557ff40 197 SUPERFAMILY SSF46689 2 84 1.39E-17 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS13250 9705f1720de8a3cedba37a281557ff40 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 3.0E-10 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS13250 9705f1720de8a3cedba37a281557ff40 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 3.0E-10 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS13250 9705f1720de8a3cedba37a281557ff40 197 SUPERFAMILY SSF48498 82 195 7.23E-17 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS13250 9705f1720de8a3cedba37a281557ff40 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 59 7.5E-16 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS16985 99104bace9c62f3a1fc2e6ee1fc259f5 414 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 5 184 2.9E-27 T 10-11-2016 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A4G23_RS16985 99104bace9c62f3a1fc2e6ee1fc259f5 414 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 314 405 1.3E-14 T 10-11-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A4G23_RS16985 99104bace9c62f3a1fc2e6ee1fc259f5 414 SUPERFAMILY SSF48179 202 292 2.38E-21 T 10-11-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A4G23_RS16985 99104bace9c62f3a1fc2e6ee1fc259f5 414 SUPERFAMILY SSF52413 300 407 8.5E-21 T 10-11-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A4G23_RS16985 99104bace9c62f3a1fc2e6ee1fc259f5 414 SUPERFAMILY SSF51735 6 196 5.03E-32 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS16985 99104bace9c62f3a1fc2e6ee1fc259f5 414 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 4 403 6.1E-98 T 10-11-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A4G23_RS16985 99104bace9c62f3a1fc2e6ee1fc259f5 414 PIRSF PIRSF500136 1 413 1.6E-122 T 10-11-2016 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 A4G23_RS16985 99104bace9c62f3a1fc2e6ee1fc259f5 414 PIRSF PIRSF000124 3 413 5.5E-44 T 10-11-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A4G23_RS16985 99104bace9c62f3a1fc2e6ee1fc259f5 414 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 202 268 1.1E-18 T 10-11-2016 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A4G23_RS16985 99104bace9c62f3a1fc2e6ee1fc259f5 414 Gene3D G3DSA:3.40.50.720 6 196 3.2E-39 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS16985 99104bace9c62f3a1fc2e6ee1fc259f5 414 Gene3D G3DSA:3.40.50.720 233 406 1.8E-32 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS16985 99104bace9c62f3a1fc2e6ee1fc259f5 414 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 5 32 - T 10-11-2016 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 A4G23_RS16985 99104bace9c62f3a1fc2e6ee1fc259f5 414 SMART SM00984 313 408 5.6E-16 T 10-11-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A4G23_RS15250 11508e2606ffd0d898dc6945a3d6e410 496 SUPERFAMILY SSF56601 126 493 1.55E-64 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS15250 11508e2606ffd0d898dc6945a3d6e410 496 Gene3D G3DSA:3.40.710.10 137 186 9.7E-8 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS15250 11508e2606ffd0d898dc6945a3d6e410 496 Gene3D G3DSA:3.40.710.10 272 494 2.6E-62 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS15250 11508e2606ffd0d898dc6945a3d6e410 496 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 161 180 3.3E-23 T 10-11-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A4G23_RS15250 11508e2606ffd0d898dc6945a3d6e410 496 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 452 465 3.3E-23 T 10-11-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A4G23_RS15250 11508e2606ffd0d898dc6945a3d6e410 496 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 387 401 3.3E-23 T 10-11-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A4G23_RS15250 11508e2606ffd0d898dc6945a3d6e410 496 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 372 386 3.3E-23 T 10-11-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A4G23_RS15250 11508e2606ffd0d898dc6945a3d6e410 496 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 315 337 3.3E-23 T 10-11-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A4G23_RS15250 11508e2606ffd0d898dc6945a3d6e410 496 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 278 492 8.5E-53 T 10-11-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A4G23_RS15250 11508e2606ffd0d898dc6945a3d6e410 496 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 123 269 6.7E-27 T 10-11-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A4G23_RS15250 11508e2606ffd0d898dc6945a3d6e410 496 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 280 473 1.1E-42 T 10-11-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A4G23_RS05690 32fde1b46c4bb27d3b07730d7d11bb46 341 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 26 326 7.3E-84 T 10-11-2016 IPR010119 Gluconeogenesis factor A4G23_RS05690 32fde1b46c4bb27d3b07730d7d11bb46 341 Hamap MF_00973 Gluconeogenesis factor. 22 333 32.831 T 10-11-2016 IPR010119 Gluconeogenesis factor A4G23_RS05690 32fde1b46c4bb27d3b07730d7d11bb46 341 Pfam PF01933 Uncharacterised protein family UPF0052 26 293 6.3E-72 T 10-11-2016 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 A4G23_RS05690 32fde1b46c4bb27d3b07730d7d11bb46 341 Gene3D G3DSA:3.40.50.10680 99 332 4.6E-44 T 10-11-2016 A4G23_RS05690 32fde1b46c4bb27d3b07730d7d11bb46 341 SUPERFAMILY SSF142338 23 327 2.75E-84 T 10-11-2016 A4G23_RS25265 cebbf60ac2835ee0d4f186220534d62b 287 SUPERFAMILY SSF110710 6 278 1.8E-83 T 10-11-2016 A4G23_RS25265 cebbf60ac2835ee0d4f186220534d62b 287 Pfam PF02522 Aminoglycoside 3-N-acetyltransferase 35 277 3.7E-68 T 10-11-2016 IPR003679 Aminoglycoside N(3)-acetyltransferase GO:0046353|GO:0046677 A4G23_RS17015 bb591877822633925287838fb404619e 523 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 259 266 - T 10-11-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 A4G23_RS17015 bb591877822633925287838fb404619e 523 Pfam PF00171 Aldehyde dehydrogenase family 32 487 1.2E-144 T 10-11-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A4G23_RS17015 bb591877822633925287838fb404619e 523 SUPERFAMILY SSF53720 29 490 3.53E-143 T 10-11-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A4G23_RS17015 bb591877822633925287838fb404619e 523 Gene3D G3DSA:3.40.309.10 274 451 1.1E-64 T 10-11-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 A4G23_RS17015 bb591877822633925287838fb404619e 523 Gene3D G3DSA:3.40.605.10 31 273 1.7E-73 T 10-11-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A4G23_RS11505 ae8346a30841368ce48499d3f6020834 226 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 47 127 6.2E-26 T 10-11-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 A4G23_RS11505 ae8346a30841368ce48499d3f6020834 226 Gene3D G3DSA:2.30.110.10 23 226 5.5E-84 T 10-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 A4G23_RS11505 ae8346a30841368ce48499d3f6020834 226 ProSitePatterns PS01064 Pyridoxamine 5'-phosphate oxidase signature. 191 204 - T 10-11-2016 IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 A4G23_RS11505 ae8346a30841368ce48499d3f6020834 226 PIRSF PIRSF000190 4 226 8.4E-82 T 10-11-2016 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 A4G23_RS11505 ae8346a30841368ce48499d3f6020834 226 Hamap MF_01629 Pyridoxine/pyridoxamine 5'-phosphate oxidase [pdxH]. 17 226 40.179 T 10-11-2016 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 A4G23_RS11505 ae8346a30841368ce48499d3f6020834 226 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 12 226 7.0E-79 T 10-11-2016 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 A4G23_RS11505 ae8346a30841368ce48499d3f6020834 226 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 181 226 7.2E-19 T 10-11-2016 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 A4G23_RS11505 ae8346a30841368ce48499d3f6020834 226 SUPERFAMILY SSF50475 23 226 3.37E-66 T 10-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 A4G23_RS10330 05af766a5578ad1b7d0037667ddbceac 256 SMART SM00382 43 229 4.6E-16 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS10330 05af766a5578ad1b7d0037667ddbceac 256 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS10330 05af766a5578ad1b7d0037667ddbceac 256 Pfam PF00005 ABC transporter 34 180 2.7E-30 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS10330 05af766a5578ad1b7d0037667ddbceac 256 SUPERFAMILY SSF52540 17 234 3.75E-70 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS10330 05af766a5578ad1b7d0037667ddbceac 256 Gene3D G3DSA:3.40.50.300 17 233 2.2E-66 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS02495 33704ee9b0567ae6b9b9a736fa9f9860 341 PIRSF PIRSF000532 1 340 3.7E-115 T 10-11-2016 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 A4G23_RS02495 33704ee9b0567ae6b9b9a736fa9f9860 341 Pfam PF00365 Phosphofructokinase 2 297 3.5E-102 T 10-11-2016 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A4G23_RS02495 33704ee9b0567ae6b9b9a736fa9f9860 341 SUPERFAMILY SSF53784 1 333 1.05E-119 T 10-11-2016 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A4G23_RS02495 33704ee9b0567ae6b9b9a736fa9f9860 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 176 193 2.4E-75 T 10-11-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A4G23_RS02495 33704ee9b0567ae6b9b9a736fa9f9860 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 212 224 2.4E-75 T 10-11-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A4G23_RS02495 33704ee9b0567ae6b9b9a736fa9f9860 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 2.4E-75 T 10-11-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A4G23_RS02495 33704ee9b0567ae6b9b9a736fa9f9860 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 120 137 2.4E-75 T 10-11-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A4G23_RS02495 33704ee9b0567ae6b9b9a736fa9f9860 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 138 156 2.4E-75 T 10-11-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A4G23_RS02495 33704ee9b0567ae6b9b9a736fa9f9860 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 158 174 2.4E-75 T 10-11-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A4G23_RS02495 33704ee9b0567ae6b9b9a736fa9f9860 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 262 284 2.4E-75 T 10-11-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A4G23_RS02495 33704ee9b0567ae6b9b9a736fa9f9860 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 5 24 2.4E-75 T 10-11-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A4G23_RS02495 33704ee9b0567ae6b9b9a736fa9f9860 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 2.4E-75 T 10-11-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A4G23_RS02495 33704ee9b0567ae6b9b9a736fa9f9860 341 ProSitePatterns PS00433 Phosphofructokinase signature. 266 284 - T 10-11-2016 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A4G23_RS02495 33704ee9b0567ae6b9b9a736fa9f9860 341 Hamap MF_01976 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 1 341 42.718 T 10-11-2016 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 A4G23_RS02495 33704ee9b0567ae6b9b9a736fa9f9860 341 Gene3D G3DSA:3.40.50.450 1 212 1.4E-73 T 10-11-2016 A4G23_RS02495 33704ee9b0567ae6b9b9a736fa9f9860 341 TIGRFAM TIGR02483 PFK_mixed: phosphofructokinase 2 323 3.7E-146 T 10-11-2016 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 A4G23_RS18675 88e8a344a6c739fab9f00dea2a08d105 328 Pfam PF00561 alpha/beta hydrolase fold 56 301 1.2E-23 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS18675 88e8a344a6c739fab9f00dea2a08d105 328 SUPERFAMILY SSF53474 29 312 5.18E-54 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS18675 88e8a344a6c739fab9f00dea2a08d105 328 PRINTS PR00111 Alpha/beta hydrolase fold signature 137 150 9.4E-6 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS18675 88e8a344a6c739fab9f00dea2a08d105 328 PRINTS PR00111 Alpha/beta hydrolase fold signature 123 136 9.4E-6 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS18675 88e8a344a6c739fab9f00dea2a08d105 328 PRINTS PR00111 Alpha/beta hydrolase fold signature 78 93 9.4E-6 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS18675 88e8a344a6c739fab9f00dea2a08d105 328 Gene3D G3DSA:3.40.50.1820 25 313 1.8E-55 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS00945 de12b6d175330ec01eccf67066c19598 486 Gene3D G3DSA:1.10.3360.10 217 306 2.7E-28 T 10-11-2016 IPR023289 VPA0735-like domain A4G23_RS00945 de12b6d175330ec01eccf67066c19598 486 Gene3D G3DSA:2.60.40.1610 86 216 1.8E-45 T 10-11-2016 IPR010679 Domain of unknown function DUF1254 A4G23_RS00945 de12b6d175330ec01eccf67066c19598 486 Gene3D G3DSA:2.60.120.600 351 485 9.3E-43 T 10-11-2016 IPR010621 Domain of unknown function DUF1214 A4G23_RS00945 de12b6d175330ec01eccf67066c19598 486 SUPERFAMILY SSF160935 26 485 1.57E-114 T 10-11-2016 A4G23_RS00945 de12b6d175330ec01eccf67066c19598 486 Pfam PF06863 Protein of unknown function (DUF1254) 88 212 4.1E-23 T 10-11-2016 IPR010679 Domain of unknown function DUF1254 A4G23_RS00945 de12b6d175330ec01eccf67066c19598 486 Pfam PF06742 Protein of unknown function (DUF1214) 363 468 6.0E-27 T 10-11-2016 IPR010621 Domain of unknown function DUF1214 A4G23_RS00480 fe86c205bca6bdf071dbf830e3f67442 92 Pfam PF04226 Transglycosylase associated protein 33 84 1.0E-10 T 10-11-2016 IPR007341 Transglycosylase-associated protein GO:0016021 A4G23_RS21740 94ce53e8fc8484a2de453aca93a7ccd3 536 Pfam PF00561 alpha/beta hydrolase fold 96 259 1.5E-21 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS21740 94ce53e8fc8484a2de453aca93a7ccd3 536 Gene3D G3DSA:3.40.50.1820 199 328 1.1E-52 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS21740 94ce53e8fc8484a2de453aca93a7ccd3 536 Gene3D G3DSA:3.40.50.1820 389 506 1.1E-52 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS21740 94ce53e8fc8484a2de453aca93a7ccd3 536 Gene3D G3DSA:3.40.50.1820 61 152 1.1E-52 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS21740 94ce53e8fc8484a2de453aca93a7ccd3 536 SUPERFAMILY SSF53474 377 494 6.95E-25 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS21740 94ce53e8fc8484a2de453aca93a7ccd3 536 SUPERFAMILY SSF53474 201 255 6.95E-25 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS21740 94ce53e8fc8484a2de453aca93a7ccd3 536 SUPERFAMILY SSF53474 89 153 6.95E-25 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS21740 94ce53e8fc8484a2de453aca93a7ccd3 536 Pfam PF08386 TAP-like protein 421 520 1.6E-25 T 10-11-2016 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal A4G23_RS03745 fb187ff7f465c62b20e72dd0900f9e38 304 Pfam PF01680 SOR/SNZ family 17 222 1.1E-107 T 10-11-2016 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A4G23_RS03745 fb187ff7f465c62b20e72dd0900f9e38 304 PIRSF PIRSF029271 5 304 8.3E-152 T 10-11-2016 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A4G23_RS03745 fb187ff7f465c62b20e72dd0900f9e38 304 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 19 304 5.7E-143 T 10-11-2016 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A4G23_RS03745 fb187ff7f465c62b20e72dd0900f9e38 304 ProSitePatterns PS01235 PdxS/SNZ family signature. 215 233 - T 10-11-2016 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A4G23_RS03745 fb187ff7f465c62b20e72dd0900f9e38 304 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 14 304 52.11 T 10-11-2016 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A4G23_RS03745 fb187ff7f465c62b20e72dd0900f9e38 304 Gene3D G3DSA:3.20.20.70 202 288 1.1E-47 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS03745 fb187ff7f465c62b20e72dd0900f9e38 304 Gene3D G3DSA:3.20.20.70 34 170 1.1E-47 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS03745 fb187ff7f465c62b20e72dd0900f9e38 304 SUPERFAMILY SSF51366 28 274 3.63E-63 T 10-11-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 A4G23_RS25540 e0013038e2c362240d54f73452088b98 299 SUPERFAMILY SSF52402 162 290 1.34E-18 T 10-11-2016 A4G23_RS25540 e0013038e2c362240d54f73452088b98 299 SUPERFAMILY SSF52402 12 148 6.61E-23 T 10-11-2016 A4G23_RS25540 e0013038e2c362240d54f73452088b98 299 Pfam PF00582 Universal stress protein family 12 145 3.8E-17 T 10-11-2016 IPR006016 UspA GO:0006950 A4G23_RS25540 e0013038e2c362240d54f73452088b98 299 Pfam PF00582 Universal stress protein family 160 288 9.9E-13 T 10-11-2016 IPR006016 UspA GO:0006950 A4G23_RS25540 e0013038e2c362240d54f73452088b98 299 Gene3D G3DSA:3.40.50.620 140 289 3.1E-20 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS25540 e0013038e2c362240d54f73452088b98 299 Gene3D G3DSA:3.40.50.620 9 139 3.1E-24 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS25540 e0013038e2c362240d54f73452088b98 299 PRINTS PR01438 Universal stress protein signature 10 28 2.0E-9 T 10-11-2016 IPR006015 Universal stress protein A A4G23_RS25540 e0013038e2c362240d54f73452088b98 299 PRINTS PR01438 Universal stress protein signature 105 117 2.0E-9 T 10-11-2016 IPR006015 Universal stress protein A A4G23_RS25540 e0013038e2c362240d54f73452088b98 299 PRINTS PR01438 Universal stress protein signature 123 145 2.0E-9 T 10-11-2016 IPR006015 Universal stress protein A A4G23_RS14460 8db9ff209136ce09922d67fe28e07203 869 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 643 661 - T 10-11-2016 IPR028299 ClpA/B, conserved site 2 A4G23_RS14460 8db9ff209136ce09922d67fe28e07203 869 SUPERFAMILY SSF81923 4 157 6.57E-29 T 10-11-2016 IPR004176 Clp, N-terminal GO:0019538 A4G23_RS14460 8db9ff209136ce09922d67fe28e07203 869 SMART SM00382 199 346 8.7E-8 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS14460 8db9ff209136ce09922d67fe28e07203 869 SMART SM00382 609 758 2.5E-12 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS14460 8db9ff209136ce09922d67fe28e07203 869 Gene3D G3DSA:1.10.8.60 788 866 2.6E-30 T 10-11-2016 A4G23_RS14460 8db9ff209136ce09922d67fe28e07203 869 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 296 308 - T 10-11-2016 IPR018368 ClpA/B, conserved site 1 GO:0005524 A4G23_RS14460 8db9ff209136ce09922d67fe28e07203 869 SUPERFAMILY SSF52540 160 526 7.72E-90 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS14460 8db9ff209136ce09922d67fe28e07203 869 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 204 338 1.1E-11 T 10-11-2016 IPR003959 ATPase, AAA-type, core GO:0005524 A4G23_RS14460 8db9ff209136ce09922d67fe28e07203 869 Pfam PF07724 AAA domain (Cdc48 subfamily) 608 770 2.7E-52 T 10-11-2016 IPR003959 ATPase, AAA-type, core GO:0005524 A4G23_RS14460 8db9ff209136ce09922d67fe28e07203 869 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 658 676 5.2E-42 T 10-11-2016 IPR001270 ClpA/B family GO:0005524 A4G23_RS14460 8db9ff209136ce09922d67fe28e07203 869 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 720 734 5.2E-42 T 10-11-2016 IPR001270 ClpA/B family GO:0005524 A4G23_RS14460 8db9ff209136ce09922d67fe28e07203 869 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 613 631 5.2E-42 T 10-11-2016 IPR001270 ClpA/B family GO:0005524 A4G23_RS14460 8db9ff209136ce09922d67fe28e07203 869 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 687 705 5.2E-42 T 10-11-2016 IPR001270 ClpA/B family GO:0005524 A4G23_RS14460 8db9ff209136ce09922d67fe28e07203 869 Gene3D G3DSA:1.10.1780.10 4 149 5.9E-31 T 10-11-2016 IPR004176 Clp, N-terminal GO:0019538 A4G23_RS14460 8db9ff209136ce09922d67fe28e07203 869 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 18 68 1.7E-4 T 10-11-2016 IPR004176 Clp, N-terminal GO:0019538 A4G23_RS14460 8db9ff209136ce09922d67fe28e07203 869 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 95 146 1.2E-11 T 10-11-2016 IPR004176 Clp, N-terminal GO:0019538 A4G23_RS14460 8db9ff209136ce09922d67fe28e07203 869 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 5 865 0.0 T 10-11-2016 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0016485 A4G23_RS14460 8db9ff209136ce09922d67fe28e07203 869 SUPERFAMILY SSF52540 558 861 5.5E-78 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS14460 8db9ff209136ce09922d67fe28e07203 869 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 776 856 2.2E-26 T 10-11-2016 IPR019489 Clp ATPase, C-terminal A4G23_RS14460 8db9ff209136ce09922d67fe28e07203 869 Gene3D G3DSA:3.40.50.300 564 787 1.6E-55 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS14460 8db9ff209136ce09922d67fe28e07203 869 SMART SM01086 776 865 5.8E-39 T 10-11-2016 IPR019489 Clp ATPase, C-terminal A4G23_RS14460 8db9ff209136ce09922d67fe28e07203 869 Gene3D G3DSA:3.40.50.300 160 343 4.2E-50 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS14460 8db9ff209136ce09922d67fe28e07203 869 Gene3D G3DSA:1.10.8.60 345 428 1.7E-35 T 10-11-2016 A4G23_RS25910 014f2e04215793b97b699f28462e6b9f 394 ProSitePatterns PS00737 Thiolases signature 2. 341 357 - T 10-11-2016 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 A4G23_RS25910 014f2e04215793b97b699f28462e6b9f 394 PIRSF PIRSF000429 1 394 1.3E-130 T 10-11-2016 IPR002155 Thiolase GO:0008152|GO:0016747 A4G23_RS25910 014f2e04215793b97b699f28462e6b9f 394 SUPERFAMILY SSF53901 5 270 1.43E-80 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS25910 014f2e04215793b97b699f28462e6b9f 394 Pfam PF02803 Thiolase, C-terminal domain 272 394 6.7E-38 T 10-11-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 A4G23_RS25910 014f2e04215793b97b699f28462e6b9f 394 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 88 106 - T 10-11-2016 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 A4G23_RS25910 014f2e04215793b97b699f28462e6b9f 394 ProSitePatterns PS00099 Thiolases active site. 376 389 - T 10-11-2016 IPR020610 Thiolase, active site GO:0008152|GO:0016747 A4G23_RS25910 014f2e04215793b97b699f28462e6b9f 394 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 8 393 2.1E-134 T 10-11-2016 IPR002155 Thiolase GO:0008152|GO:0016747 A4G23_RS25910 014f2e04215793b97b699f28462e6b9f 394 Gene3D G3DSA:3.40.47.10 202 277 1.4E-68 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS25910 014f2e04215793b97b699f28462e6b9f 394 Gene3D G3DSA:3.40.47.10 5 127 1.4E-68 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS25910 014f2e04215793b97b699f28462e6b9f 394 Gene3D G3DSA:3.40.47.10 161 201 3.6E-50 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS25910 014f2e04215793b97b699f28462e6b9f 394 Gene3D G3DSA:3.40.47.10 278 393 3.6E-50 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS25910 014f2e04215793b97b699f28462e6b9f 394 Pfam PF00108 Thiolase, N-terminal domain 6 264 2.9E-75 T 10-11-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 A4G23_RS25910 014f2e04215793b97b699f28462e6b9f 394 SUPERFAMILY SSF53901 272 394 2.16E-35 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS08775 5ed00500f2c56124b22b29f9aa02be9b 352 Gene3D G3DSA:1.10.260.40 3 62 7.7E-21 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS08775 5ed00500f2c56124b22b29f9aa02be9b 352 Gene3D G3DSA:3.40.50.2300 191 324 2.7E-52 T 10-11-2016 A4G23_RS08775 5ed00500f2c56124b22b29f9aa02be9b 352 SUPERFAMILY SSF53822 62 350 2.36E-59 T 10-11-2016 IPR028082 Periplasmic binding protein-like I A4G23_RS08775 5ed00500f2c56124b22b29f9aa02be9b 352 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 5.8E-17 T 10-11-2016 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4G23_RS08775 5ed00500f2c56124b22b29f9aa02be9b 352 Gene3D G3DSA:3.40.50.2300 63 190 2.2E-41 T 10-11-2016 A4G23_RS08775 5ed00500f2c56124b22b29f9aa02be9b 352 Pfam PF13377 Periplasmic binding protein-like domain 187 347 3.8E-32 T 10-11-2016 A4G23_RS08775 5ed00500f2c56124b22b29f9aa02be9b 352 SUPERFAMILY SSF47413 2 60 9.29E-16 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS08775 5ed00500f2c56124b22b29f9aa02be9b 352 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 10-11-2016 A4G23_RS08775 5ed00500f2c56124b22b29f9aa02be9b 352 SMART SM00354 2 72 1.3E-24 T 10-11-2016 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4G23_RS17200 b7e3e15a9c1e570cfb8fb91a27e229fe 212 SUPERFAMILY SSF53328 10 208 1.19E-58 T 10-11-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A4G23_RS17200 b7e3e15a9c1e570cfb8fb91a27e229fe 212 Pfam PF00551 Formyl transferase 10 193 1.7E-52 T 10-11-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A4G23_RS17200 b7e3e15a9c1e570cfb8fb91a27e229fe 212 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 10 203 6.2E-68 T 10-11-2016 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 A4G23_RS17200 b7e3e15a9c1e570cfb8fb91a27e229fe 212 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 10 199 29.288 T 10-11-2016 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 A4G23_RS17200 b7e3e15a9c1e570cfb8fb91a27e229fe 212 Gene3D G3DSA:3.40.50.170 9 206 5.2E-70 T 10-11-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A4G23_RS17200 b7e3e15a9c1e570cfb8fb91a27e229fe 212 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 145 168 - T 10-11-2016 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A4G23_RS26820 2f922409aa8da62dedaf870001a5eeed 473 Gene3D G3DSA:3.40.50.300 238 380 1.9E-38 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS26820 2f922409aa8da62dedaf870001a5eeed 473 SMART SM00490 282 363 1.7E-28 T 10-11-2016 IPR001650 Helicase, C-terminal A4G23_RS26820 2f922409aa8da62dedaf870001a5eeed 473 Pfam PF00271 Helicase conserved C-terminal domain 265 363 4.0E-22 T 10-11-2016 IPR001650 Helicase, C-terminal A4G23_RS26820 2f922409aa8da62dedaf870001a5eeed 473 SMART SM00487 48 248 1.7E-50 T 10-11-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4G23_RS26820 2f922409aa8da62dedaf870001a5eeed 473 Gene3D G3DSA:3.40.50.300 23 237 1.2E-69 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS26820 2f922409aa8da62dedaf870001a5eeed 473 SUPERFAMILY SSF52540 100 376 2.43E-63 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS26820 2f922409aa8da62dedaf870001a5eeed 473 Pfam PF00270 DEAD/DEAH box helicase 54 220 5.7E-43 T 10-11-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A4G23_RS02190 189c10b3ed0858613e58ba6349481835 478 SUPERFAMILY SSF50370 349 476 2.8E-44 T 10-11-2016 IPR000772 Ricin B, lectin domain A4G23_RS02190 189c10b3ed0858613e58ba6349481835 478 Gene3D G3DSA:2.80.10.50 348 476 2.6E-46 T 10-11-2016 A4G23_RS02190 189c10b3ed0858613e58ba6349481835 478 Pfam PF00652 Ricin-type beta-trefoil lectin domain 354 475 1.3E-30 T 10-11-2016 IPR000772 Ricin B, lectin domain A4G23_RS02190 189c10b3ed0858613e58ba6349481835 478 SMART SM00458 354 478 4.5E-37 T 10-11-2016 IPR000772 Ricin B, lectin domain A4G23_RS02190 189c10b3ed0858613e58ba6349481835 478 Gene3D G3DSA:3.20.20.80 47 346 1.3E-112 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS02190 189c10b3ed0858613e58ba6349481835 478 SMART SM00633 88 341 8.6E-143 T 10-11-2016 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 A4G23_RS02190 189c10b3ed0858613e58ba6349481835 478 SUPERFAMILY SSF51445 44 342 2.91E-109 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS02190 189c10b3ed0858613e58ba6349481835 478 PRINTS PR00134 Glycosyl hydrolase family 10 signature 161 172 1.2E-16 T 10-11-2016 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 A4G23_RS02190 189c10b3ed0858613e58ba6349481835 478 PRINTS PR00134 Glycosyl hydrolase family 10 signature 236 248 1.2E-16 T 10-11-2016 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 A4G23_RS02190 189c10b3ed0858613e58ba6349481835 478 PRINTS PR00134 Glycosyl hydrolase family 10 signature 119 131 1.2E-16 T 10-11-2016 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 A4G23_RS02190 189c10b3ed0858613e58ba6349481835 478 PRINTS PR00134 Glycosyl hydrolase family 10 signature 206 217 1.2E-16 T 10-11-2016 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 A4G23_RS02190 189c10b3ed0858613e58ba6349481835 478 ProSitePatterns PS00591 Glycosyl hydrolases family 10 (GH10) active site. 270 280 - T 10-11-2016 IPR031158 Glycosyl hydrolases family 10, active site MetaCyc: PWY-6784 A4G23_RS02190 189c10b3ed0858613e58ba6349481835 478 Pfam PF00331 Glycosyl hydrolase family 10 47 339 6.9E-107 T 10-11-2016 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 A4G23_RS04990 2ba1b1bf2097fdb5cd3f7245cf6e37c6 275 SUPERFAMILY SSF48452 26 189 7.28E-9 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS04990 2ba1b1bf2097fdb5cd3f7245cf6e37c6 275 Gene3D G3DSA:1.25.40.10 17 78 2.0E-8 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS04990 2ba1b1bf2097fdb5cd3f7245cf6e37c6 275 Gene3D G3DSA:1.25.40.10 147 191 2.0E-8 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS04990 2ba1b1bf2097fdb5cd3f7245cf6e37c6 275 Pfam PF14559 Tetratricopeptide repeat 131 189 2.6E-6 T 10-11-2016 A4G23_RS06085 4fa05e67d7ef11611cb4725fb0df5c39 246 SMART SM00464 5 222 1.8E-45 T 10-11-2016 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 A4G23_RS06085 4fa05e67d7ef11611cb4725fb0df5c39 246 SUPERFAMILY SSF88697 5 221 5.72E-40 T 10-11-2016 IPR015947 PUA-like domain A4G23_RS06085 4fa05e67d7ef11611cb4725fb0df5c39 246 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 6 221 3.9E-30 T 10-11-2016 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 A4G23_RS12050 a1a1b01013d904fc6b4dd7359e254053 308 PIRSF PIRSF000535 1 304 1.1E-76 T 10-11-2016 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 A4G23_RS12050 a1a1b01013d904fc6b4dd7359e254053 308 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 301 1.4E-88 T 10-11-2016 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 A4G23_RS12050 a1a1b01013d904fc6b4dd7359e254053 308 SUPERFAMILY SSF53613 2 284 3.43E-62 T 10-11-2016 IPR029056 Ribokinase-like A4G23_RS12050 a1a1b01013d904fc6b4dd7359e254053 308 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 36 60 - T 10-11-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A4G23_RS12050 a1a1b01013d904fc6b4dd7359e254053 308 Pfam PF00294 pfkB family carbohydrate kinase 11 284 1.3E-41 T 10-11-2016 IPR011611 Carbohydrate kinase PfkB A4G23_RS12050 a1a1b01013d904fc6b4dd7359e254053 308 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 242 255 - T 10-11-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A4G23_RS12050 a1a1b01013d904fc6b4dd7359e254053 308 Gene3D G3DSA:3.40.1190.20 36 303 3.0E-74 T 10-11-2016 IPR029056 Ribokinase-like A4G23_RS12050 a1a1b01013d904fc6b4dd7359e254053 308 Gene3D G3DSA:2.20.150.10 10 35 2.6E-4 T 10-11-2016 IPR023314 Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain KEGG: 00052+2.7.1.144|KEGG: 00710+2.7.1.14|MetaCyc: PWY-7077|MetaCyc: PWY-7395 A4G23_RS16055 75857c25cb9e6d584c76e196bf9c9351 241 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 100 221 7.8E-40 T 10-11-2016 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16055 75857c25cb9e6d584c76e196bf9c9351 241 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 98 220 5.4E-44 T 10-11-2016 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16055 75857c25cb9e6d584c76e196bf9c9351 241 Hamap MF_01357 NAD(P)H-quinone oxidoreductase subunit J, chloroplastic [ndhJ]. 72 229 28.656 T 10-11-2016 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16055 75857c25cb9e6d584c76e196bf9c9351 241 SUPERFAMILY SSF143243 85 237 7.85E-46 T 10-11-2016 A4G23_RS16055 75857c25cb9e6d584c76e196bf9c9351 241 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 149 204 9.0E-24 T 10-11-2016 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS04630 c7a9bb9a42f6bfbf6c350f0f3da826d2 384 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 337 356 - T 10-11-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A4G23_RS04630 c7a9bb9a42f6bfbf6c350f0f3da826d2 384 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 10-11-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A4G23_RS04630 c7a9bb9a42f6bfbf6c350f0f3da826d2 384 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 118 4.7E-38 T 10-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 A4G23_RS04630 c7a9bb9a42f6bfbf6c350f0f3da826d2 384 SUPERFAMILY SSF56645 2 242 3.53E-85 T 10-11-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 A4G23_RS04630 c7a9bb9a42f6bfbf6c350f0f3da826d2 384 Gene3D G3DSA:1.20.140.10 219 380 5.9E-66 T 10-11-2016 A4G23_RS04630 c7a9bb9a42f6bfbf6c350f0f3da826d2 384 Gene3D G3DSA:2.40.110.10 121 218 2.3E-39 T 10-11-2016 A4G23_RS04630 c7a9bb9a42f6bfbf6c350f0f3da826d2 384 SUPERFAMILY SSF47203 229 380 1.08E-55 T 10-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4G23_RS04630 c7a9bb9a42f6bfbf6c350f0f3da826d2 384 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 218 9.0E-30 T 10-11-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 A4G23_RS04630 c7a9bb9a42f6bfbf6c350f0f3da826d2 384 PIRSF PIRSF016578 4 382 5.1E-22 T 10-11-2016 A4G23_RS04630 c7a9bb9a42f6bfbf6c350f0f3da826d2 384 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 230 378 1.1E-48 T 10-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4G23_RS04630 c7a9bb9a42f6bfbf6c350f0f3da826d2 384 Gene3D G3DSA:1.10.540.10 2 118 1.2E-42 T 10-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 A4G23_RS27050 b134a673b8b12047117a5c1e7b91072f 276 PRINTS PR00069 Aldo-keto reductase signature 37 61 3.1E-47 T 10-11-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4G23_RS27050 b134a673b8b12047117a5c1e7b91072f 276 PRINTS PR00069 Aldo-keto reductase signature 197 221 3.1E-47 T 10-11-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4G23_RS27050 b134a673b8b12047117a5c1e7b91072f 276 PRINTS PR00069 Aldo-keto reductase signature 159 188 3.1E-47 T 10-11-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4G23_RS27050 b134a673b8b12047117a5c1e7b91072f 276 PRINTS PR00069 Aldo-keto reductase signature 93 111 3.1E-47 T 10-11-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4G23_RS27050 b134a673b8b12047117a5c1e7b91072f 276 PRINTS PR00069 Aldo-keto reductase signature 125 142 3.1E-47 T 10-11-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4G23_RS27050 b134a673b8b12047117a5c1e7b91072f 276 Pfam PF00248 Aldo/keto reductase family 18 261 1.7E-50 T 10-11-2016 IPR023210 NADP-dependent oxidoreductase domain A4G23_RS27050 b134a673b8b12047117a5c1e7b91072f 276 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 125 142 - T 10-11-2016 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 A4G23_RS27050 b134a673b8b12047117a5c1e7b91072f 276 Gene3D G3DSA:3.20.20.100 5 271 6.4E-106 T 10-11-2016 IPR023210 NADP-dependent oxidoreductase domain A4G23_RS27050 b134a673b8b12047117a5c1e7b91072f 276 SUPERFAMILY SSF51430 6 267 1.44E-95 T 10-11-2016 IPR023210 NADP-dependent oxidoreductase domain A4G23_RS27050 b134a673b8b12047117a5c1e7b91072f 276 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 230 245 - T 10-11-2016 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 A4G23_RS27050 b134a673b8b12047117a5c1e7b91072f 276 PIRSF PIRSF000097 2 269 5.0E-87 T 10-11-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4G23_RS11560 8f9b75b7fc43d4c89f158fe16aa483ce 395 Gene3D G3DSA:1.20.140.10 229 394 1.8E-46 T 10-11-2016 A4G23_RS11560 8f9b75b7fc43d4c89f158fe16aa483ce 395 SUPERFAMILY SSF47203 236 393 2.9E-40 T 10-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4G23_RS11560 8f9b75b7fc43d4c89f158fe16aa483ce 395 Gene3D G3DSA:1.10.540.10 21 126 1.7E-25 T 10-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 A4G23_RS11560 8f9b75b7fc43d4c89f158fe16aa483ce 395 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 240 379 3.5E-32 T 10-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4G23_RS11560 8f9b75b7fc43d4c89f158fe16aa483ce 395 SUPERFAMILY SSF56645 22 251 2.62E-54 T 10-11-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 A4G23_RS11560 8f9b75b7fc43d4c89f158fe16aa483ce 395 Gene3D G3DSA:2.40.110.10 130 228 1.7E-22 T 10-11-2016 A4G23_RS11560 8f9b75b7fc43d4c89f158fe16aa483ce 395 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 130 222 7.0E-16 T 10-11-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 A4G23_RS11560 8f9b75b7fc43d4c89f158fe16aa483ce 395 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 22 125 2.5E-24 T 10-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 A4G23_RS19285 a155748ef4a1c99e9b0be7c7a4ee15e3 175 SUPERFAMILY SSF103196 14 52 7.15E-7 T 10-11-2016 A4G23_RS19285 a155748ef4a1c99e9b0be7c7a4ee15e3 175 SMART SM00960 20 135 3.0E-15 T 10-11-2016 IPR004942 Roadblock/LAMTOR2 domain A4G23_RS19285 a155748ef4a1c99e9b0be7c7a4ee15e3 175 Pfam PF03259 Roadblock/LC7 domain 83 133 6.4E-8 T 10-11-2016 IPR004942 Roadblock/LAMTOR2 domain A4G23_RS19285 a155748ef4a1c99e9b0be7c7a4ee15e3 175 Gene3D G3DSA:3.30.450.30 14 50 1.3E-4 T 10-11-2016 A4G23_RS19285 a155748ef4a1c99e9b0be7c7a4ee15e3 175 Gene3D G3DSA:3.30.450.30 84 159 1.2E-9 T 10-11-2016 A4G23_RS19285 a155748ef4a1c99e9b0be7c7a4ee15e3 175 SUPERFAMILY SSF103196 78 163 5.41E-13 T 10-11-2016 A4G23_RS15195 ae82218f68b83acd84c7b6478035f4b8 81 ProSitePatterns PS00057 Ribosomal protein S18 signature. 27 50 - T 10-11-2016 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS15195 ae82218f68b83acd84c7b6478035f4b8 81 Pfam PF01084 Ribosomal protein S18 24 74 1.2E-24 T 10-11-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS15195 ae82218f68b83acd84c7b6478035f4b8 81 TIGRFAM TIGR00165 S18: ribosomal protein bS18 22 77 2.0E-23 T 10-11-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS15195 ae82218f68b83acd84c7b6478035f4b8 81 Gene3D G3DSA:4.10.640.10 15 77 5.5E-30 T 10-11-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS15195 ae82218f68b83acd84c7b6478035f4b8 81 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 4 79 20.28 T 10-11-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS15195 ae82218f68b83acd84c7b6478035f4b8 81 PRINTS PR00974 Ribosomal protein S18 family signature 52 66 7.1E-18 T 10-11-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS15195 ae82218f68b83acd84c7b6478035f4b8 81 PRINTS PR00974 Ribosomal protein S18 family signature 44 51 7.1E-18 T 10-11-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS15195 ae82218f68b83acd84c7b6478035f4b8 81 PRINTS PR00974 Ribosomal protein S18 family signature 34 44 7.1E-18 T 10-11-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS15195 ae82218f68b83acd84c7b6478035f4b8 81 PRINTS PR00974 Ribosomal protein S18 family signature 66 76 7.1E-18 T 10-11-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS15195 ae82218f68b83acd84c7b6478035f4b8 81 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 26 76 1.0E-10 T 10-11-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS15195 ae82218f68b83acd84c7b6478035f4b8 81 SUPERFAMILY SSF46911 8 78 1.7E-26 T 10-11-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS11845 544558aca7eb99a5b427842114810455 683 Gene3D G3DSA:3.40.50.300 518 679 4.0E-19 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS11845 544558aca7eb99a5b427842114810455 683 SUPERFAMILY SSF52540 438 676 1.5E-41 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS11845 544558aca7eb99a5b427842114810455 683 SUPERFAMILY SSF52540 358 391 1.5E-41 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS11845 544558aca7eb99a5b427842114810455 683 SUPERFAMILY SSF52540 173 252 1.5E-41 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS11845 544558aca7eb99a5b427842114810455 683 Pfam PF13245 Part of AAA domain 193 252 2.1E-13 T 10-11-2016 A4G23_RS11845 544558aca7eb99a5b427842114810455 683 Pfam PF13538 UvrD-like helicase C-terminal domain 628 667 5.6E-7 T 10-11-2016 IPR027785 UvrD-like helicase C-terminal domain A4G23_RS11845 544558aca7eb99a5b427842114810455 683 Gene3D G3DSA:3.40.50.300 378 513 3.7E-30 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS11845 544558aca7eb99a5b427842114810455 683 Gene3D G3DSA:3.40.50.300 180 242 3.7E-30 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS03355 ced863bbae4adb01bae4eb4c8a473264 90 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 7 90 1.6E-23 T 10-11-2016 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 A4G23_RS03355 ced863bbae4adb01bae4eb4c8a473264 90 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 19 89 1.1E-9 T 10-11-2016 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 A4G23_RS03355 ced863bbae4adb01bae4eb4c8a473264 90 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 3 90 19.423 T 10-11-2016 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 A4G23_RS03355 ced863bbae4adb01bae4eb4c8a473264 90 SUPERFAMILY SSF101386 5 90 2.62E-20 T 10-11-2016 A4G23_RS01410 fc55746b06b3f4c7febe7d08bb86c1fb 398 Gene3D G3DSA:2.40.50.100 374 388 4.3E-8 T 10-11-2016 A4G23_RS01410 fc55746b06b3f4c7febe7d08bb86c1fb 398 Gene3D G3DSA:2.40.50.100 240 284 4.3E-8 T 10-11-2016 A4G23_RS01410 fc55746b06b3f4c7febe7d08bb86c1fb 398 Pfam PF00005 ABC transporter 21 162 1.7E-30 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS01410 fc55746b06b3f4c7febe7d08bb86c1fb 398 SUPERFAMILY SSF52540 4 243 5.59E-86 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS01410 fc55746b06b3f4c7febe7d08bb86c1fb 398 SMART SM00382 29 212 3.6E-13 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS01410 fc55746b06b3f4c7febe7d08bb86c1fb 398 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS01410 fc55746b06b3f4c7febe7d08bb86c1fb 398 Gene3D G3DSA:3.40.50.300 4 236 5.2E-78 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS01410 fc55746b06b3f4c7febe7d08bb86c1fb 398 Gene3D G3DSA:2.40.50.140 285 373 5.2E-7 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS01410 fc55746b06b3f4c7febe7d08bb86c1fb 398 SUPERFAMILY SSF50331 237 388 8.26E-20 T 10-11-2016 IPR008995 Molybdate/tungstate binding, C-terminal A4G23_RS14905 fc27d09dbde89e4ca95dc98c9e0e7693 367 TIGRFAM TIGR03815 CpaE_hom_Actino: helicase/secretion neighborhood CpaE-like protein 23 358 1.0E-105 T 10-11-2016 IPR022521 Conserved hypothetical protein CHP03815, CpaE-like A4G23_RS14905 fc27d09dbde89e4ca95dc98c9e0e7693 367 SUPERFAMILY SSF52540 133 344 7.27E-27 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS14905 fc27d09dbde89e4ca95dc98c9e0e7693 367 Gene3D G3DSA:3.40.50.300 133 360 1.3E-25 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS14905 fc27d09dbde89e4ca95dc98c9e0e7693 367 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 136 294 2.0E-9 T 10-11-2016 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A4G23_RS05920 f1ad81167f96453f08c2e1bdd696e3bc 830 SUPERFAMILY SSF63737 3 189 9.15E-35 T 10-11-2016 A4G23_RS05920 f1ad81167f96453f08c2e1bdd696e3bc 830 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 253 263 5.9E-21 T 10-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4G23_RS05920 f1ad81167f96453f08c2e1bdd696e3bc 830 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 172 187 5.9E-21 T 10-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4G23_RS05920 f1ad81167f96453f08c2e1bdd696e3bc 830 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 129 144 5.9E-21 T 10-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4G23_RS05920 f1ad81167f96453f08c2e1bdd696e3bc 830 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 287 302 5.9E-21 T 10-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4G23_RS05920 f1ad81167f96453f08c2e1bdd696e3bc 830 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 306 318 5.9E-21 T 10-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4G23_RS05920 f1ad81167f96453f08c2e1bdd696e3bc 830 Pfam PF11838 ERAP1-like C-terminal domain 513 823 2.5E-46 T 10-11-2016 IPR024571 ERAP1-like C-terminal domain A4G23_RS05920 f1ad81167f96453f08c2e1bdd696e3bc 830 Pfam PF01433 Peptidase family M1 87 383 3.9E-62 T 10-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4G23_RS05920 f1ad81167f96453f08c2e1bdd696e3bc 830 TIGRFAM TIGR02412 pepN_strep_liv: aminopeptidase N 4 829 0.0 T 10-11-2016 IPR012778 Peptidase M1, aminopeptidase GO:0004177|GO:0006508 KEGG: 00480+3.4.11.2|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112 A4G23_RS05920 f1ad81167f96453f08c2e1bdd696e3bc 830 SUPERFAMILY SSF55486 198 450 5.13E-67 T 10-11-2016 A4G23_RS05920 f1ad81167f96453f08c2e1bdd696e3bc 830 Gene3D G3DSA:1.10.390.10 300 451 2.5E-35 T 10-11-2016 A4G23_RS20475 8e805f2bf4bf13a3b593844e1053dcfe 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 8.0E-40 T 10-11-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A4G23_RS20475 8e805f2bf4bf13a3b593844e1053dcfe 112 SMART SM00938 4 105 5.1E-59 T 10-11-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A4G23_RS20475 8e805f2bf4bf13a3b593844e1053dcfe 112 PIRSF PIRSF039144 1 112 2.5E-50 T 10-11-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A4G23_RS20475 8e805f2bf4bf13a3b593844e1053dcfe 112 Gene3D G3DSA:3.30.70.120 1 112 1.1E-46 T 10-11-2016 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal A4G23_RS20475 8e805f2bf4bf13a3b593844e1053dcfe 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 10-11-2016 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 A4G23_RS20475 8e805f2bf4bf13a3b593844e1053dcfe 112 SUPERFAMILY SSF54913 1 112 1.87E-42 T 10-11-2016 IPR011322 Nitrogen regulatory PII-like, alpha/beta A4G23_RS20475 8e805f2bf4bf13a3b593844e1053dcfe 112 PRINTS PR00340 P-II protein signature 2 17 1.5E-36 T 10-11-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A4G23_RS20475 8e805f2bf4bf13a3b593844e1053dcfe 112 PRINTS PR00340 P-II protein signature 23 41 1.5E-36 T 10-11-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A4G23_RS20475 8e805f2bf4bf13a3b593844e1053dcfe 112 PRINTS PR00340 P-II protein signature 52 75 1.5E-36 T 10-11-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A4G23_RS20475 8e805f2bf4bf13a3b593844e1053dcfe 112 PRINTS PR00340 P-II protein signature 83 103 1.5E-36 T 10-11-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A4G23_RS03385 98ccc492a70037f94fa96c7537c4b069 774 Gene3D G3DSA:3.10.50.10 389 432 6.4E-18 T 10-11-2016 IPR029070 Chitinase insertion domain A4G23_RS03385 98ccc492a70037f94fa96c7537c4b069 774 Gene3D G3DSA:3.10.50.10 472 491 6.4E-18 T 10-11-2016 IPR029070 Chitinase insertion domain A4G23_RS03385 98ccc492a70037f94fa96c7537c4b069 774 SUPERFAMILY SSF51055 722 774 7.85E-15 T 10-11-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 A4G23_RS03385 98ccc492a70037f94fa96c7537c4b069 774 ProSitePatterns PS01095 Chitinases family 18 active site. 224 232 - T 10-11-2016 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 A4G23_RS03385 98ccc492a70037f94fa96c7537c4b069 774 SMART SM00636 72 525 8.9E-120 T 10-11-2016 IPR011583 Chitinase II GO:0004568|GO:0006032 A4G23_RS03385 98ccc492a70037f94fa96c7537c4b069 774 Gene3D G3DSA:2.10.10.20 724 771 5.2E-19 T 10-11-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 A4G23_RS03385 98ccc492a70037f94fa96c7537c4b069 774 Gene3D G3DSA:3.20.20.80 434 435 3.8E-92 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS03385 98ccc492a70037f94fa96c7537c4b069 774 Gene3D G3DSA:3.20.20.80 492 548 3.8E-92 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS03385 98ccc492a70037f94fa96c7537c4b069 774 Gene3D G3DSA:3.20.20.80 70 331 3.8E-92 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS03385 98ccc492a70037f94fa96c7537c4b069 774 Gene3D G3DSA:3.20.20.80 365 388 3.8E-92 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS03385 98ccc492a70037f94fa96c7537c4b069 774 Pfam PF02839 Carbohydrate binding domain 726 768 2.1E-10 T 10-11-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 A4G23_RS03385 98ccc492a70037f94fa96c7537c4b069 774 SUPERFAMILY SSF51445 66 382 4.11E-76 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS03385 98ccc492a70037f94fa96c7537c4b069 774 SUPERFAMILY SSF51445 497 529 4.11E-76 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS03385 98ccc492a70037f94fa96c7537c4b069 774 SUPERFAMILY SSF54556 382 495 1.73E-13 T 10-11-2016 IPR029070 Chitinase insertion domain A4G23_RS03385 98ccc492a70037f94fa96c7537c4b069 774 Pfam PF00704 Glycosyl hydrolases family 18 73 525 1.4E-79 T 10-11-2016 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0004553|GO:0005975 A4G23_RS03385 98ccc492a70037f94fa96c7537c4b069 774 Pfam PF06483 Chitinase C 534 705 1.1E-81 T 10-11-2016 IPR009470 Chitinase, C-terminal KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 A4G23_RS03385 98ccc492a70037f94fa96c7537c4b069 774 SMART SM00495 726 771 9.2E-16 T 10-11-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 A4G23_RS12530 fa43d674a57d55c1fc7c63dc74d4b175 332 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 110 320 3.7E-14 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS12530 fa43d674a57d55c1fc7c63dc74d4b175 332 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 31 324 2.5E-89 T 10-11-2016 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 A4G23_RS12530 fa43d674a57d55c1fc7c63dc74d4b175 332 SUPERFAMILY SSF161098 53 316 2.49E-32 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS12530 fa43d674a57d55c1fc7c63dc74d4b175 332 Gene3D G3DSA:1.10.3720.10 42 328 3.1E-36 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS21410 8ab2ecac733cbfa6c39ad06190aedefc 817 Gene3D G3DSA:2.120.10.90 513 804 9.4E-44 T 10-11-2016 A4G23_RS21410 8ab2ecac733cbfa6c39ad06190aedefc 817 SMART SM00434 21 476 1.4E-255 T 10-11-2016 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4G23_RS21410 8ab2ecac733cbfa6c39ad06190aedefc 817 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 668 713 3.6E-6 T 10-11-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A4G23_RS21410 8ab2ecac733cbfa6c39ad06190aedefc 817 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 739 772 0.059 T 10-11-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A4G23_RS21410 8ab2ecac733cbfa6c39ad06190aedefc 817 SUPERFAMILY SSF56719 41 498 1.16E-163 T 10-11-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 A4G23_RS21410 8ab2ecac733cbfa6c39ad06190aedefc 817 Gene3D G3DSA:3.90.199.10 345 410 8.1E-110 T 10-11-2016 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 A4G23_RS21410 8ab2ecac733cbfa6c39ad06190aedefc 817 Gene3D G3DSA:3.90.199.10 41 246 8.1E-110 T 10-11-2016 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 A4G23_RS21410 8ab2ecac733cbfa6c39ad06190aedefc 817 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 42 483 1.8E-146 T 10-11-2016 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4G23_RS21410 8ab2ecac733cbfa6c39ad06190aedefc 817 SUPERFAMILY SSF101904 513 774 5.75E-43 T 10-11-2016 A4G23_RS21410 8ab2ecac733cbfa6c39ad06190aedefc 817 Gene3D G3DSA:3.30.1360.40 247 344 1.7E-27 T 10-11-2016 IPR024946 Arginine repressor C-terminal-like domain A4G23_RS00090 1c9b947f6bee332111cc1ac2c5d47e86 384 Pfam PF00665 Integrase core domain 8 116 2.3E-9 T 10-11-2016 IPR001584 Integrase, catalytic core GO:0015074 A4G23_RS00090 1c9b947f6bee332111cc1ac2c5d47e86 384 Gene3D G3DSA:3.30.420.10 14 180 2.8E-19 T 10-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 A4G23_RS00090 1c9b947f6bee332111cc1ac2c5d47e86 384 SUPERFAMILY SSF53098 13 175 1.67E-14 T 10-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 A4G23_RS00090 1c9b947f6bee332111cc1ac2c5d47e86 384 Gene3D G3DSA:2.30.30.130 196 257 8.2E-7 T 10-11-2016 IPR009004 Transposase, Mu, C-terminal A4G23_RS00090 1c9b947f6bee332111cc1ac2c5d47e86 384 Pfam PF09299 Mu transposase, C-terminal 200 253 1.0E-8 T 10-11-2016 IPR015378 Transposase-like, Mu, C-terminal A4G23_RS22455 b810a0ae4de5cf0a4b506862bc7b2f01 1002 ProSitePatterns PS00622 LuxR-type HTH domain signature. 955 982 - T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS22455 b810a0ae4de5cf0a4b506862bc7b2f01 1002 SUPERFAMILY SSF46894 933 995 9.18E-17 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS22455 b810a0ae4de5cf0a4b506862bc7b2f01 1002 SUPERFAMILY SSF52540 10 60 1.75E-7 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS22455 b810a0ae4de5cf0a4b506862bc7b2f01 1002 SUPERFAMILY SSF52540 119 257 1.75E-7 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS22455 b810a0ae4de5cf0a4b506862bc7b2f01 1002 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 955 971 2.1E-9 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS22455 b810a0ae4de5cf0a4b506862bc7b2f01 1002 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 941 955 2.1E-9 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS22455 b810a0ae4de5cf0a4b506862bc7b2f01 1002 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 971 983 2.1E-9 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS22455 b810a0ae4de5cf0a4b506862bc7b2f01 1002 SMART SM00421 938 995 1.9E-21 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS22455 b810a0ae4de5cf0a4b506862bc7b2f01 1002 Gene3D G3DSA:1.10.10.10 939 994 4.4E-20 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS22455 b810a0ae4de5cf0a4b506862bc7b2f01 1002 Gene3D G3DSA:1.25.40.10 633 667 1.9E-5 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS22455 b810a0ae4de5cf0a4b506862bc7b2f01 1002 Gene3D G3DSA:1.25.40.10 832 876 1.9E-5 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS22455 b810a0ae4de5cf0a4b506862bc7b2f01 1002 Gene3D G3DSA:1.25.40.10 449 472 1.9E-5 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS22455 b810a0ae4de5cf0a4b506862bc7b2f01 1002 Pfam PF00196 Bacterial regulatory proteins, luxR family 939 993 3.1E-15 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS06045 eac3a5989e21c306683f1eee591014fc 135 Gene3D G3DSA:3.30.1330.40 5 129 3.4E-30 T 10-11-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like A4G23_RS06045 eac3a5989e21c306683f1eee591014fc 135 SUPERFAMILY SSF55298 4 128 4.24E-24 T 10-11-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like A4G23_RS06045 eac3a5989e21c306683f1eee591014fc 135 Pfam PF01042 Endoribonuclease L-PSP 19 126 4.0E-14 T 10-11-2016 IPR006175 YjgF/YER057c/UK114 family A4G23_RS25585 67b25a7c406edb87093bf9905bcf61fd 686 SUPERFAMILY SSF81345 20 344 4.45E-52 T 10-11-2016 IPR029022 ABC transporter, BtuC-like A4G23_RS25585 67b25a7c406edb87093bf9905bcf61fd 686 Pfam PF01032 FecCD transport family 377 683 4.0E-85 T 10-11-2016 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 A4G23_RS25585 67b25a7c406edb87093bf9905bcf61fd 686 Pfam PF01032 FecCD transport family 32 344 3.1E-64 T 10-11-2016 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 A4G23_RS25585 67b25a7c406edb87093bf9905bcf61fd 686 SUPERFAMILY SSF81345 357 683 3.79E-75 T 10-11-2016 IPR029022 ABC transporter, BtuC-like A4G23_RS25585 67b25a7c406edb87093bf9905bcf61fd 686 Gene3D G3DSA:1.10.3470.10 20 347 1.1E-70 T 10-11-2016 IPR029022 ABC transporter, BtuC-like A4G23_RS25585 67b25a7c406edb87093bf9905bcf61fd 686 Gene3D G3DSA:1.10.3470.10 366 686 1.8E-89 T 10-11-2016 IPR029022 ABC transporter, BtuC-like A4G23_RS04485 5d1c1d6af2cbc8cb1ce3fe2912e7b042 759 SUPERFAMILY SSF117125 669 745 1.22E-11 T 10-11-2016 A4G23_RS04485 5d1c1d6af2cbc8cb1ce3fe2912e7b042 759 SUPERFAMILY SSF51011 589 667 2.23E-22 T 10-11-2016 A4G23_RS04485 5d1c1d6af2cbc8cb1ce3fe2912e7b042 759 Pfam PF13802 Galactose mutarotase-like 162 221 1.8E-15 T 10-11-2016 IPR025887 Glycoside hydrolase family 31, N-terminal domain A4G23_RS04485 5d1c1d6af2cbc8cb1ce3fe2912e7b042 759 SUPERFAMILY SSF51445 251 588 6.67E-96 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS04485 5d1c1d6af2cbc8cb1ce3fe2912e7b042 759 Gene3D G3DSA:3.20.20.70 279 353 1.6E-12 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS04485 5d1c1d6af2cbc8cb1ce3fe2912e7b042 759 Gene3D G3DSA:3.20.20.70 388 467 1.6E-12 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS04485 5d1c1d6af2cbc8cb1ce3fe2912e7b042 759 Pfam PF01055 Glycosyl hydrolases family 31 243 672 3.3E-123 T 10-11-2016 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 A4G23_RS04485 5d1c1d6af2cbc8cb1ce3fe2912e7b042 759 SUPERFAMILY SSF74650 1 250 2.1E-62 T 10-11-2016 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 A4G23_RS03490 2b4e342d4149efead5d01552579ba43e 478 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 351 362 - T 10-11-2016 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A4G23_RS03490 2b4e342d4149efead5d01552579ba43e 478 Gene3D G3DSA:3.40.50.150 263 476 9.6E-42 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS03490 2b4e342d4149efead5d01552579ba43e 478 Pfam PF01029 NusB family 21 146 3.2E-24 T 10-11-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 A4G23_RS03490 2b4e342d4149efead5d01552579ba43e 478 Pfam PF01189 16S rRNA methyltransferase RsmB/F 282 475 1.4E-43 T 10-11-2016 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A4G23_RS03490 2b4e342d4149efead5d01552579ba43e 478 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 402 418 1.2E-20 T 10-11-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A4G23_RS03490 2b4e342d4149efead5d01552579ba43e 478 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 459 476 1.2E-20 T 10-11-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A4G23_RS03490 2b4e342d4149efead5d01552579ba43e 478 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 286 296 1.2E-20 T 10-11-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A4G23_RS03490 2b4e342d4149efead5d01552579ba43e 478 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 352 364 1.2E-20 T 10-11-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A4G23_RS03490 2b4e342d4149efead5d01552579ba43e 478 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 253 267 1.2E-20 T 10-11-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A4G23_RS03490 2b4e342d4149efead5d01552579ba43e 478 SUPERFAMILY SSF48013 21 178 1.09E-33 T 10-11-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 A4G23_RS03490 2b4e342d4149efead5d01552579ba43e 478 Gene3D G3DSA:1.10.940.10 18 180 7.5E-46 T 10-11-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 A4G23_RS03490 2b4e342d4149efead5d01552579ba43e 478 SUPERFAMILY SSF53335 167 476 1.05E-51 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS10680 84c00804bccf9d95959b18641963b9b3 295 PIRSF PIRSF005917 1 280 3.6E-88 T 10-11-2016 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A4G23_RS10680 84c00804bccf9d95959b18641963b9b3 295 Gene3D G3DSA:3.30.950.10 114 225 2.9E-43 T 10-11-2016 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A4G23_RS10680 84c00804bccf9d95959b18641963b9b3 295 SUPERFAMILY SSF53790 3 222 4.06E-72 T 10-11-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A4G23_RS10680 84c00804bccf9d95959b18641963b9b3 295 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 207 4.1E-29 T 10-11-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A4G23_RS10680 84c00804bccf9d95959b18641963b9b3 295 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 4 224 32.844 T 10-11-2016 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A4G23_RS10680 84c00804bccf9d95959b18641963b9b3 295 Gene3D G3DSA:3.40.1010.10 3 113 7.7E-6 T 10-11-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A4G23_RS10680 84c00804bccf9d95959b18641963b9b3 295 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 6 272 1.8E-60 T 10-11-2016 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A4G23_RS21200 5fab62735570c4eacbe70000cffb45db 274 SMART SM00079 35 260 0.0036 T 10-11-2016 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 A4G23_RS21200 5fab62735570c4eacbe70000cffb45db 274 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 58 71 - T 10-11-2016 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 A4G23_RS21200 5fab62735570c4eacbe70000cffb45db 274 SMART SM00062 35 261 5.8E-66 T 10-11-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A4G23_RS21200 5fab62735570c4eacbe70000cffb45db 274 Gene3D G3DSA:3.40.190.10 116 221 1.5E-22 T 10-11-2016 A4G23_RS21200 5fab62735570c4eacbe70000cffb45db 274 SUPERFAMILY SSF53850 6 259 8.08E-57 T 10-11-2016 A4G23_RS21200 5fab62735570c4eacbe70000cffb45db 274 Gene3D G3DSA:3.40.190.10 34 115 7.1E-32 T 10-11-2016 A4G23_RS21200 5fab62735570c4eacbe70000cffb45db 274 Gene3D G3DSA:3.40.190.10 222 260 7.1E-32 T 10-11-2016 A4G23_RS21200 5fab62735570c4eacbe70000cffb45db 274 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 36 259 1.1E-50 T 10-11-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A4G23_RS20070 fec0b437563c1950f04e23be86584637 98 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 20 91 1.1E-16 T 10-11-2016 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 A4G23_RS20070 fec0b437563c1950f04e23be86584637 98 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 3 96 23.898 T 10-11-2016 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 A4G23_RS20070 fec0b437563c1950f04e23be86584637 98 SUPERFAMILY SSF141000 4 94 5.49E-28 T 10-11-2016 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 A4G23_RS20070 fec0b437563c1950f04e23be86584637 98 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 4 95 2.5E-25 T 10-11-2016 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 A4G23_RS14600 dc0992368a2f472859ca3a66984b39b2 226 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 1.3E-8 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS14600 dc0992368a2f472859ca3a66984b39b2 226 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 1.3E-8 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS14600 dc0992368a2f472859ca3a66984b39b2 226 SUPERFAMILY SSF48498 88 195 2.97E-20 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS14600 dc0992368a2f472859ca3a66984b39b2 226 SUPERFAMILY SSF46689 14 91 2.49E-18 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS14600 dc0992368a2f472859ca3a66984b39b2 226 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 69 2.8E-14 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS14600 dc0992368a2f472859ca3a66984b39b2 226 Gene3D G3DSA:1.10.357.10 13 200 5.5E-44 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS03685 2f2dd1e5b55e32684745c48d25a36c82 409 Pfam PF03993 Domain of Unknown Function (DUF349) 168 241 4.7E-20 T 10-11-2016 IPR007139 Protein of unknown function DUF349 A4G23_RS03685 2f2dd1e5b55e32684745c48d25a36c82 409 Pfam PF03993 Domain of Unknown Function (DUF349) 245 318 4.6E-20 T 10-11-2016 IPR007139 Protein of unknown function DUF349 A4G23_RS03685 2f2dd1e5b55e32684745c48d25a36c82 409 Pfam PF03993 Domain of Unknown Function (DUF349) 91 164 6.7E-13 T 10-11-2016 IPR007139 Protein of unknown function DUF349 A4G23_RS03930 a336b65e47bf082be291accb0cd1134a 223 Gene3D G3DSA:1.10.3720.10 7 211 3.9E-39 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS03930 a336b65e47bf082be291accb0cd1134a 223 SUPERFAMILY SSF161098 8 202 3.14E-43 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS03930 a336b65e47bf082be291accb0cd1134a 223 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 218 6.9E-19 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS13120 5fc51de40d7346859958c5858b080d5c 431 Hamap MF_00467 Probable M18 family aminopeptidase 2 [apeB]. 1 431 56.594 T 10-11-2016 IPR022984 M18 family aminopeptidase 2, putative GO:0004177 A4G23_RS13120 5fc51de40d7346859958c5858b080d5c 431 Pfam PF02127 Aminopeptidase I zinc metalloprotease (M18) 19 429 1.6E-129 T 10-11-2016 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 A4G23_RS13120 5fc51de40d7346859958c5858b080d5c 431 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 81 97 1.4E-36 T 10-11-2016 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 A4G23_RS13120 5fc51de40d7346859958c5858b080d5c 431 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 114 134 1.4E-36 T 10-11-2016 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 A4G23_RS13120 5fc51de40d7346859958c5858b080d5c 431 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 308 324 1.4E-36 T 10-11-2016 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 A4G23_RS13120 5fc51de40d7346859958c5858b080d5c 431 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 397 412 1.4E-36 T 10-11-2016 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 A4G23_RS13120 5fc51de40d7346859958c5858b080d5c 431 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 265 283 1.4E-36 T 10-11-2016 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 A4G23_RS13120 5fc51de40d7346859958c5858b080d5c 431 Gene3D G3DSA:3.40.630.10 12 91 8.3E-106 T 10-11-2016 A4G23_RS13120 5fc51de40d7346859958c5858b080d5c 431 Gene3D G3DSA:3.40.630.10 221 431 8.3E-106 T 10-11-2016 A4G23_RS13120 5fc51de40d7346859958c5858b080d5c 431 SUPERFAMILY SSF53187 10 92 4.83E-98 T 10-11-2016 A4G23_RS13120 5fc51de40d7346859958c5858b080d5c 431 SUPERFAMILY SSF53187 212 431 4.83E-98 T 10-11-2016 A4G23_RS13120 5fc51de40d7346859958c5858b080d5c 431 SUPERFAMILY SSF101821 93 212 1.19E-33 T 10-11-2016 A4G23_RS13120 5fc51de40d7346859958c5858b080d5c 431 Gene3D G3DSA:2.30.250.10 92 218 1.3E-40 T 10-11-2016 IPR023358 Peptidase M18, domain 2 GO:0004177 A4G23_RS06405 85c72f19749853a834563f71ef741a7e 956 SMART SM00644 318 457 3.0E-44 T 10-11-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 A4G23_RS06405 85c72f19749853a834563f71ef741a7e 956 Gene3D G3DSA:2.115.10.10 711 847 4.6E-15 T 10-11-2016 IPR023294 Tachylectin 2 A4G23_RS06405 85c72f19749853a834563f71ef741a7e 956 Gene3D G3DSA:2.115.10.10 848 952 4.0E-11 T 10-11-2016 IPR023294 Tachylectin 2 A4G23_RS06405 85c72f19749853a834563f71ef741a7e 956 SUPERFAMILY SSF55846 317 470 5.47E-38 T 10-11-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 A4G23_RS06405 85c72f19749853a834563f71ef741a7e 956 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 804 866 2.3E-8 T 10-11-2016 A4G23_RS06405 85c72f19749853a834563f71ef741a7e 956 Gene3D G3DSA:3.40.80.10 318 469 1.1E-37 T 10-11-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 A4G23_RS06405 85c72f19749853a834563f71ef741a7e 956 SUPERFAMILY SSF69318 674 947 2.22E-22 T 10-11-2016 A4G23_RS06405 85c72f19749853a834563f71ef741a7e 956 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 328 458 4.8E-21 T 10-11-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 A4G23_RS06405 85c72f19749853a834563f71ef741a7e 956 Gene3D G3DSA:1.10.530.10 180 246 1.5E-7 T 10-11-2016 A4G23_RS06405 85c72f19749853a834563f71ef741a7e 956 Gene3D G3DSA:1.10.530.10 53 117 1.5E-7 T 10-11-2016 A4G23_RS01975 2cd7fd55f4cbe1c6a515ca806c135f42 854 Pfam PF02151 UvrB/uvrC motif 468 501 4.5E-7 T 10-11-2016 IPR001943 UVR domain GO:0005515 A4G23_RS01975 2cd7fd55f4cbe1c6a515ca806c135f42 854 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 345 357 - T 10-11-2016 IPR018368 ClpA/B, conserved site 1 GO:0005524 A4G23_RS01975 2cd7fd55f4cbe1c6a515ca806c135f42 854 Gene3D G3DSA:1.10.8.60 395 478 3.3E-34 T 10-11-2016 A4G23_RS01975 2cd7fd55f4cbe1c6a515ca806c135f42 854 SUPERFAMILY SSF52540 535 852 9.1E-80 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS01975 2cd7fd55f4cbe1c6a515ca806c135f42 854 SUPERFAMILY SSF52540 205 479 8.63E-70 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS01975 2cd7fd55f4cbe1c6a515ca806c135f42 854 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 249 368 2.8E-11 T 10-11-2016 IPR003959 ATPase, AAA-type, core GO:0005524 A4G23_RS01975 2cd7fd55f4cbe1c6a515ca806c135f42 854 SUPERFAMILY SSF81923 46 150 5.57E-16 T 10-11-2016 IPR004176 Clp, N-terminal GO:0019538 A4G23_RS01975 2cd7fd55f4cbe1c6a515ca806c135f42 854 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 620 638 - T 10-11-2016 IPR028299 ClpA/B, conserved site 2 A4G23_RS01975 2cd7fd55f4cbe1c6a515ca806c135f42 854 Gene3D G3DSA:1.10.1780.10 46 171 1.1E-24 T 10-11-2016 IPR004176 Clp, N-terminal GO:0019538 A4G23_RS01975 2cd7fd55f4cbe1c6a515ca806c135f42 854 SMART SM01086 763 852 5.0E-35 T 10-11-2016 IPR019489 Clp ATPase, C-terminal A4G23_RS01975 2cd7fd55f4cbe1c6a515ca806c135f42 854 SMART SM00382 586 727 4.3E-11 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS01975 2cd7fd55f4cbe1c6a515ca806c135f42 854 SMART SM00382 244 394 1.2E-10 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS01975 2cd7fd55f4cbe1c6a515ca806c135f42 854 Gene3D G3DSA:3.40.50.300 206 393 8.1E-45 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS01975 2cd7fd55f4cbe1c6a515ca806c135f42 854 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 635 653 8.1E-42 T 10-11-2016 IPR001270 ClpA/B family GO:0005524 A4G23_RS01975 2cd7fd55f4cbe1c6a515ca806c135f42 854 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 664 682 8.1E-42 T 10-11-2016 IPR001270 ClpA/B family GO:0005524 A4G23_RS01975 2cd7fd55f4cbe1c6a515ca806c135f42 854 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 697 711 8.1E-42 T 10-11-2016 IPR001270 ClpA/B family GO:0005524 A4G23_RS01975 2cd7fd55f4cbe1c6a515ca806c135f42 854 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 590 608 8.1E-42 T 10-11-2016 IPR001270 ClpA/B family GO:0005524 A4G23_RS01975 2cd7fd55f4cbe1c6a515ca806c135f42 854 Gene3D G3DSA:1.10.8.60 772 853 1.9E-28 T 10-11-2016 A4G23_RS01975 2cd7fd55f4cbe1c6a515ca806c135f42 854 Pfam PF07724 AAA domain (Cdc48 subfamily) 585 757 1.8E-51 T 10-11-2016 IPR003959 ATPase, AAA-type, core GO:0005524 A4G23_RS01975 2cd7fd55f4cbe1c6a515ca806c135f42 854 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 128 171 3.9E-10 T 10-11-2016 IPR004176 Clp, N-terminal GO:0019538 A4G23_RS01975 2cd7fd55f4cbe1c6a515ca806c135f42 854 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 57 104 8.3E-7 T 10-11-2016 IPR004176 Clp, N-terminal GO:0019538 A4G23_RS01975 2cd7fd55f4cbe1c6a515ca806c135f42 854 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 763 843 1.1E-25 T 10-11-2016 IPR019489 Clp ATPase, C-terminal A4G23_RS01975 2cd7fd55f4cbe1c6a515ca806c135f42 854 Gene3D G3DSA:3.40.50.300 540 712 3.5E-54 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS01975 2cd7fd55f4cbe1c6a515ca806c135f42 854 Gene3D G3DSA:3.40.50.300 746 771 3.5E-54 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS25620 b43005713ba9cc7b5b79c1e0945300c1 168 Pfam PF03073 TspO/MBR family 24 164 8.9E-42 T 10-11-2016 IPR004307 TspO/MBR-related protein GO:0016021 A4G23_RS25620 b43005713ba9cc7b5b79c1e0945300c1 168 PIRSF PIRSF005859 11 168 1.2E-46 T 10-11-2016 IPR004307 TspO/MBR-related protein GO:0016021 A4G23_RS24695 45f13b8a98a06aed8f4d322774d2cf04 268 SUPERFAMILY SSF54593 138 263 1.48E-16 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS24695 45f13b8a98a06aed8f4d322774d2cf04 268 SUPERFAMILY SSF54593 9 123 1.48E-19 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS24695 45f13b8a98a06aed8f4d322774d2cf04 268 Gene3D G3DSA:3.10.180.10 138 264 3.2E-26 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS24695 45f13b8a98a06aed8f4d322774d2cf04 268 Gene3D G3DSA:3.10.180.10 10 124 3.3E-34 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS10010 27c6f4f9773f77651cc4cb68c8c57c42 590 SMART SM00701 394 542 6.1E-54 T 10-11-2016 IPR006619 Peptidoglycan recognition protein family domain, metazoa/bacteria GO:0008270|GO:0008745|GO:0009253 A4G23_RS10010 27c6f4f9773f77651cc4cb68c8c57c42 590 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 417 569 1.4E-9 T 10-11-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 A4G23_RS10010 27c6f4f9773f77651cc4cb68c8c57c42 590 Gene3D G3DSA:3.40.80.10 394 584 3.2E-50 T 10-11-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 A4G23_RS10010 27c6f4f9773f77651cc4cb68c8c57c42 590 SUPERFAMILY SSF55846 394 581 8.06E-48 T 10-11-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 A4G23_RS09690 4ee3ac59dcbd787c1aa3fb00344e58dc 452 Gene3D G3DSA:1.20.1250.20 227 430 9.9E-16 T 10-11-2016 A4G23_RS09690 4ee3ac59dcbd787c1aa3fb00344e58dc 452 Gene3D G3DSA:1.20.1250.20 27 211 2.8E-12 T 10-11-2016 A4G23_RS09690 4ee3ac59dcbd787c1aa3fb00344e58dc 452 Pfam PF07690 Major Facilitator Superfamily 40 388 2.7E-19 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS09690 4ee3ac59dcbd787c1aa3fb00344e58dc 452 SUPERFAMILY SSF103473 8 427 3.4E-40 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS09690 4ee3ac59dcbd787c1aa3fb00344e58dc 452 ProSitePatterns PS00216 Sugar transport proteins signature 1. 360 377 - T 10-11-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A4G23_RS24560 ed6f43df0eab4428e5ccc53c58ee051b 284 PIRSF PIRSF015626 1 276 4.4E-86 T 10-11-2016 IPR003786 Protein FdhD GO:0016783 A4G23_RS24560 ed6f43df0eab4428e5ccc53c58ee051b 284 Pfam PF02634 FdhD/NarQ family 26 273 1.9E-79 T 10-11-2016 IPR003786 Protein FdhD GO:0016783 A4G23_RS24560 ed6f43df0eab4428e5ccc53c58ee051b 284 SUPERFAMILY SSF53927 4 273 5.11E-78 T 10-11-2016 IPR016193 Cytidine deaminase-like GO:0003824 A4G23_RS24560 ed6f43df0eab4428e5ccc53c58ee051b 284 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 22 273 4.8E-48 T 10-11-2016 IPR003786 Protein FdhD GO:0016783 A4G23_RS24560 ed6f43df0eab4428e5ccc53c58ee051b 284 Gene3D G3DSA:3.10.20.10 28 119 4.7E-27 T 10-11-2016 A4G23_RS24560 ed6f43df0eab4428e5ccc53c58ee051b 284 Gene3D G3DSA:3.40.140.10 140 274 9.2E-54 T 10-11-2016 A4G23_RS24560 ed6f43df0eab4428e5ccc53c58ee051b 284 Hamap MF_00187 Sulfurtransferase FdhD [fdhD]. 2 274 34.451 T 10-11-2016 IPR003786 Protein FdhD GO:0016783 A4G23_RS20770 337454f75b7a46a79ac82d899d620637 324 Pfam PF00196 Bacterial regulatory proteins, luxR family 263 313 1.1E-7 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS20770 337454f75b7a46a79ac82d899d620637 324 Gene3D G3DSA:1.10.10.10 251 322 3.1E-13 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS20770 337454f75b7a46a79ac82d899d620637 324 SUPERFAMILY SSF46894 243 323 1.16E-12 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS20770 337454f75b7a46a79ac82d899d620637 324 Gene3D G3DSA:1.10.10.10 2 49 3.2E-4 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS20770 337454f75b7a46a79ac82d899d620637 324 SMART SM00421 260 317 1.1E-9 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS24035 2081f88f59335704c606bdc3b4b7ebf8 2432 Gene3D G3DSA:1.10.1200.10 1010 1070 1.5E-19 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS24035 2081f88f59335704c606bdc3b4b7ebf8 2432 Gene3D G3DSA:1.10.1200.10 2074 2137 8.6E-21 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS24035 2081f88f59335704c606bdc3b4b7ebf8 2432 Gene3D G3DSA:3.40.50.980 640 809 5.6E-43 T 10-11-2016 A4G23_RS24035 2081f88f59335704c606bdc3b4b7ebf8 2432 Gene3D G3DSA:3.40.50.980 1702 1858 1.6E-28 T 10-11-2016 A4G23_RS24035 2081f88f59335704c606bdc3b4b7ebf8 2432 SMART SM00824 Thioesterase 2159 2419 8.3E-4 T 10-11-2016 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 A4G23_RS24035 2081f88f59335704c606bdc3b4b7ebf8 2432 SUPERFAMILY SSF52777 1292 1528 2.89E-43 T 10-11-2016 A4G23_RS24035 2081f88f59335704c606bdc3b4b7ebf8 2432 Pfam PF00975 Thioesterase domain 2158 2412 2.6E-35 T 10-11-2016 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 A4G23_RS24035 2081f88f59335704c606bdc3b4b7ebf8 2432 SUPERFAMILY SSF47336 2062 2134 7.72E-16 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS24035 2081f88f59335704c606bdc3b4b7ebf8 2432 ProSitePatterns PS00455 Putative AMP-binding domain signature. 631 642 - T 10-11-2016 IPR020845 AMP-binding, conserved site A4G23_RS24035 2081f88f59335704c606bdc3b4b7ebf8 2432 SMART SM00823 Phosphopantetheine attachment site 2069 2138 8.4E-4 T 10-11-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4G23_RS24035 2081f88f59335704c606bdc3b4b7ebf8 2432 SMART SM00823 Phosphopantetheine attachment site 1005 1073 0.091 T 10-11-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4G23_RS24035 2081f88f59335704c606bdc3b4b7ebf8 2432 SUPERFAMILY SSF53474 2138 2421 4.66E-62 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS24035 2081f88f59335704c606bdc3b4b7ebf8 2432 Gene3D G3DSA:2.30.38.10 810 887 1.5E-30 T 10-11-2016 A4G23_RS24035 2081f88f59335704c606bdc3b4b7ebf8 2432 Gene3D G3DSA:2.30.38.10 1867 1944 2.7E-22 T 10-11-2016 A4G23_RS24035 2081f88f59335704c606bdc3b4b7ebf8 2432 SUPERFAMILY SSF52777 222 454 1.45E-37 T 10-11-2016 A4G23_RS24035 2081f88f59335704c606bdc3b4b7ebf8 2432 SUPERFAMILY SSF56801 451 1017 7.72E-160 T 10-11-2016 A4G23_RS24035 2081f88f59335704c606bdc3b4b7ebf8 2432 Gene3D G3DSA:3.40.50.980 1550 1701 6.9E-40 T 10-11-2016 A4G23_RS24035 2081f88f59335704c606bdc3b4b7ebf8 2432 Gene3D G3DSA:3.30.300.30 892 1009 2.0E-34 T 10-11-2016 A4G23_RS24035 2081f88f59335704c606bdc3b4b7ebf8 2432 Gene3D G3DSA:3.30.300.30 1951 2073 1.6E-29 T 10-11-2016 A4G23_RS24035 2081f88f59335704c606bdc3b4b7ebf8 2432 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1696 1707 - T 10-11-2016 IPR020845 AMP-binding, conserved site A4G23_RS24035 2081f88f59335704c606bdc3b4b7ebf8 2432 SUPERFAMILY SSF52777 1110 1287 7.23E-25 T 10-11-2016 A4G23_RS24035 2081f88f59335704c606bdc3b4b7ebf8 2432 SUPERFAMILY SSF56801 1545 2082 3.79E-131 T 10-11-2016 A4G23_RS24035 2081f88f59335704c606bdc3b4b7ebf8 2432 SUPERFAMILY SSF52777 1 158 6.45E-28 T 10-11-2016 A4G23_RS24035 2081f88f59335704c606bdc3b4b7ebf8 2432 Pfam PF00501 AMP-binding enzyme 1555 1955 2.1E-81 T 10-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A4G23_RS24035 2081f88f59335704c606bdc3b4b7ebf8 2432 Pfam PF00501 AMP-binding enzyme 492 897 7.7E-101 T 10-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A4G23_RS24035 2081f88f59335704c606bdc3b4b7ebf8 2432 Gene3D G3DSA:3.40.50.980 484 639 5.8E-50 T 10-11-2016 A4G23_RS24035 2081f88f59335704c606bdc3b4b7ebf8 2432 Gene3D G3DSA:3.40.50.1820 2344 2421 2.1E-52 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS24035 2081f88f59335704c606bdc3b4b7ebf8 2432 Gene3D G3DSA:3.40.50.1820 2142 2261 2.1E-52 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS24035 2081f88f59335704c606bdc3b4b7ebf8 2432 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1576 1971 3.6E-109 T 10-11-2016 IPR010071 Amino acid adenylation domain A4G23_RS24035 2081f88f59335704c606bdc3b4b7ebf8 2432 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 515 921 1.7E-133 T 10-11-2016 IPR010071 Amino acid adenylation domain A4G23_RS24035 2081f88f59335704c606bdc3b4b7ebf8 2432 SUPERFAMILY SSF47336 999 1067 4.71E-14 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS24035 2081f88f59335704c606bdc3b4b7ebf8 2432 Pfam PF13193 AMP-binding enzyme C-terminal domain 905 979 5.7E-6 T 10-11-2016 IPR025110 AMP-binding enzyme C-terminal domain A4G23_RS24035 2081f88f59335704c606bdc3b4b7ebf8 2432 Pfam PF13193 AMP-binding enzyme C-terminal domain 1970 2042 1.2E-7 T 10-11-2016 IPR025110 AMP-binding enzyme C-terminal domain A4G23_RS24035 2081f88f59335704c606bdc3b4b7ebf8 2432 PRINTS PR00154 AMP-binding signature 626 637 6.3E-5 T 10-11-2016 IPR020459 AMP-binding A4G23_RS24035 2081f88f59335704c606bdc3b4b7ebf8 2432 PRINTS PR00154 AMP-binding signature 638 646 6.3E-5 T 10-11-2016 IPR020459 AMP-binding A4G23_RS24035 2081f88f59335704c606bdc3b4b7ebf8 2432 Pfam PF00550 Phosphopantetheine attachment site 1007 1067 3.5E-9 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS24035 2081f88f59335704c606bdc3b4b7ebf8 2432 Pfam PF00550 Phosphopantetheine attachment site 2071 2133 3.1E-13 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS24035 2081f88f59335704c606bdc3b4b7ebf8 2432 Pfam PF00668 Condensation domain 214 325 6.0E-8 T 10-11-2016 IPR001242 Condensation domain A4G23_RS24035 2081f88f59335704c606bdc3b4b7ebf8 2432 Pfam PF00668 Condensation domain 1104 1402 5.8E-44 T 10-11-2016 IPR001242 Condensation domain A4G23_RS24035 2081f88f59335704c606bdc3b4b7ebf8 2432 Pfam PF00668 Condensation domain 1 186 2.8E-17 T 10-11-2016 IPR001242 Condensation domain A4G23_RS03800 d9f6acec6cc35ad46cbd2c3fa75d0f67 186 Pfam PF14280 Domain of unknown function (DUF4365) 32 179 3.2E-22 T 10-11-2016 IPR025375 Domain of unknown function DUF4365 A4G23_RS11980 74b2883c16d99195a07d6822ae8ef838 480 Pfam PF01235 Sodium:alanine symporter family 62 456 1.4E-154 T 10-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A4G23_RS11980 74b2883c16d99195a07d6822ae8ef838 480 TIGRFAM TIGR00835 agcS: amino acid carrier protein 16 444 1.2E-142 T 10-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A4G23_RS11980 74b2883c16d99195a07d6822ae8ef838 480 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 94 109 - T 10-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A4G23_RS11980 74b2883c16d99195a07d6822ae8ef838 480 PRINTS PR00175 Sodium/alanine symporter signature 353 375 2.8E-53 T 10-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A4G23_RS11980 74b2883c16d99195a07d6822ae8ef838 480 PRINTS PR00175 Sodium/alanine symporter signature 94 116 2.8E-53 T 10-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A4G23_RS11980 74b2883c16d99195a07d6822ae8ef838 480 PRINTS PR00175 Sodium/alanine symporter signature 218 237 2.8E-53 T 10-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A4G23_RS11980 74b2883c16d99195a07d6822ae8ef838 480 PRINTS PR00175 Sodium/alanine symporter signature 190 208 2.8E-53 T 10-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A4G23_RS11980 74b2883c16d99195a07d6822ae8ef838 480 PRINTS PR00175 Sodium/alanine symporter signature 309 327 2.8E-53 T 10-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A4G23_RS11980 74b2883c16d99195a07d6822ae8ef838 480 PRINTS PR00175 Sodium/alanine symporter signature 413 433 2.8E-53 T 10-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A4G23_RS06380 f8c3fe0ac089a356b0f8318c694ff808 300 Pfam PF01261 Xylose isomerase-like TIM barrel 16 237 8.3E-34 T 10-11-2016 IPR013022 Xylose isomerase-like, TIM barrel domain A4G23_RS06380 f8c3fe0ac089a356b0f8318c694ff808 300 ProSitePatterns PS00731 AP endonucleases family 2 signature 3. 213 229 - T 10-11-2016 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 A4G23_RS06380 f8c3fe0ac089a356b0f8318c694ff808 300 SUPERFAMILY SSF51658 1 278 9.82E-75 T 10-11-2016 IPR013022 Xylose isomerase-like, TIM barrel domain A4G23_RS06380 f8c3fe0ac089a356b0f8318c694ff808 300 SMART SM00518 1 278 8.7E-103 T 10-11-2016 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 A4G23_RS06380 f8c3fe0ac089a356b0f8318c694ff808 300 ProSitePatterns PS00729 AP endonucleases family 2 signature 1. 64 72 - T 10-11-2016 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 A4G23_RS06380 f8c3fe0ac089a356b0f8318c694ff808 300 Gene3D G3DSA:3.20.20.150 1 279 5.0E-84 T 10-11-2016 IPR013022 Xylose isomerase-like, TIM barrel domain A4G23_RS06380 f8c3fe0ac089a356b0f8318c694ff808 300 TIGRFAM TIGR00587 nfo: apurinic endonuclease (APN1) 1 275 6.4E-61 T 10-11-2016 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 A4G23_RS06380 f8c3fe0ac089a356b0f8318c694ff808 300 Hamap MF_00152 Probable endonuclease 4 [nfo]. 1 278 37.137 T 10-11-2016 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 A4G23_RS06380 f8c3fe0ac089a356b0f8318c694ff808 300 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 173 180 - T 10-11-2016 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 A4G23_RS23485 86ca35b8b0ff258c0b9f30b4bbd7d9bd 183 Gene3D G3DSA:3.10.20.30 13 86 4.8E-32 T 10-11-2016 IPR012675 Beta-grasp domain A4G23_RS23485 86ca35b8b0ff258c0b9f30b4bbd7d9bd 183 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 18 64 3.0E-9 T 10-11-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A4G23_RS23485 86ca35b8b0ff258c0b9f30b4bbd7d9bd 183 SUPERFAMILY SSF54292 13 90 4.98E-26 T 10-11-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A4G23_RS23485 86ca35b8b0ff258c0b9f30b4bbd7d9bd 183 SUPERFAMILY SSF47741 98 182 1.7E-25 T 10-11-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 A4G23_RS23485 86ca35b8b0ff258c0b9f30b4bbd7d9bd 183 Gene3D G3DSA:1.10.150.120 87 182 3.6E-28 T 10-11-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 A4G23_RS23485 86ca35b8b0ff258c0b9f30b4bbd7d9bd 183 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 51 59 - T 10-11-2016 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 A4G23_RS23485 86ca35b8b0ff258c0b9f30b4bbd7d9bd 183 Pfam PF01799 [2Fe-2S] binding domain 85 178 7.6E-28 T 10-11-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 A4G23_RS22890 91a5e954e9ae7ba4cd461700d49e1398 654 Pfam PF02780 Transketolase, C-terminal domain 499 612 2.1E-29 T 10-11-2016 IPR033248 Transketolase, C-terminal domain A4G23_RS22890 91a5e954e9ae7ba4cd461700d49e1398 654 Gene3D G3DSA:3.40.50.970 239 330 1.3E-61 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS22890 91a5e954e9ae7ba4cd461700d49e1398 654 Gene3D G3DSA:3.40.50.970 19 194 1.3E-61 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS22890 91a5e954e9ae7ba4cd461700d49e1398 654 SUPERFAMILY SSF52518 294 477 9.64E-51 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS22890 91a5e954e9ae7ba4cd461700d49e1398 654 SUPERFAMILY SSF52518 3 345 2.85E-72 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS22890 91a5e954e9ae7ba4cd461700d49e1398 654 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 3 621 41.728 T 10-11-2016 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A4G23_RS22890 91a5e954e9ae7ba4cd461700d49e1398 654 ProSitePatterns PS00802 Transketolase signature 2. 421 437 - T 10-11-2016 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A4G23_RS22890 91a5e954e9ae7ba4cd461700d49e1398 654 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 4 279 1.0E-107 T 10-11-2016 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A4G23_RS22890 91a5e954e9ae7ba4cd461700d49e1398 654 ProSitePatterns PS00801 Transketolase signature 1. 29 48 - T 10-11-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A4G23_RS22890 91a5e954e9ae7ba4cd461700d49e1398 654 Gene3D G3DSA:3.40.50.970 331 481 1.2E-28 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS22890 91a5e954e9ae7ba4cd461700d49e1398 654 Gene3D G3DSA:3.40.50.920 488 619 7.5E-32 T 10-11-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 A4G23_RS22890 91a5e954e9ae7ba4cd461700d49e1398 654 SUPERFAMILY SSF52922 487 620 1.44E-27 T 10-11-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 A4G23_RS22890 91a5e954e9ae7ba4cd461700d49e1398 654 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 6 617 1.7E-191 T 10-11-2016 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A4G23_RS22890 91a5e954e9ae7ba4cd461700d49e1398 654 SMART SM00861 315 479 1.3E-49 T 10-11-2016 IPR005475 Transketolase-like, pyrimidine-binding domain A4G23_RS22890 91a5e954e9ae7ba4cd461700d49e1398 654 Pfam PF02779 Transketolase, pyrimidine binding domain 315 477 9.1E-37 T 10-11-2016 IPR005475 Transketolase-like, pyrimidine-binding domain A4G23_RS09715 d34ee0b15b184bae26290174c8d6e241 159 Gene3D G3DSA:2.40.280.10 8 128 1.3E-53 T 10-11-2016 IPR023620 Small protein B A4G23_RS09715 d34ee0b15b184bae26290174c8d6e241 159 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 10 133 3.0E-60 T 10-11-2016 IPR000037 SsrA-binding protein GO:0003723 A4G23_RS09715 d34ee0b15b184bae26290174c8d6e241 159 SUPERFAMILY SSF74982 3 133 1.18E-53 T 10-11-2016 IPR023620 Small protein B A4G23_RS09715 d34ee0b15b184bae26290174c8d6e241 159 Pfam PF01668 SmpB protein 9 72 1.7E-31 T 10-11-2016 IPR000037 SsrA-binding protein GO:0003723 A4G23_RS09715 d34ee0b15b184bae26290174c8d6e241 159 TIGRFAM TIGR00086 smpB: SsrA-binding protein 10 150 1.4E-58 T 10-11-2016 IPR000037 SsrA-binding protein GO:0003723 A4G23_RS09715 d34ee0b15b184bae26290174c8d6e241 159 ProSitePatterns PS01317 SsrA-binding protein. 28 40 - T 10-11-2016 IPR020081 SsrA-binding protein, conserved site A4G23_RS09715 d34ee0b15b184bae26290174c8d6e241 159 Hamap MF_00023 SsrA-binding protein [smpB]. 1 159 74.38 T 10-11-2016 IPR000037 SsrA-binding protein GO:0003723 A4G23_RS02785 0ce8eb88228886ea5f458e3443a3333f 480 Pfam PF00392 Bacterial regulatory proteins, gntR family 29 88 1.0E-16 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS02785 0ce8eb88228886ea5f458e3443a3333f 480 SMART SM00345 29 88 1.6E-18 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS02785 0ce8eb88228886ea5f458e3443a3333f 480 SUPERFAMILY SSF46785 23 90 9.8E-19 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS02785 0ce8eb88228886ea5f458e3443a3333f 480 SUPERFAMILY SSF53383 85 470 1.18E-78 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS02785 0ce8eb88228886ea5f458e3443a3333f 480 Pfam PF00155 Aminotransferase class I and II 138 402 2.0E-14 T 10-11-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4G23_RS02785 0ce8eb88228886ea5f458e3443a3333f 480 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 62 1.7E-7 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS02785 0ce8eb88228886ea5f458e3443a3333f 480 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 62 78 1.7E-7 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS02785 0ce8eb88228886ea5f458e3443a3333f 480 Gene3D G3DSA:1.10.10.10 23 89 2.3E-22 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS02785 0ce8eb88228886ea5f458e3443a3333f 480 Gene3D G3DSA:3.40.640.10 146 358 4.8E-47 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS02035 e7e347dc8ecce4ec18d5e122dc124a52 373 SUPERFAMILY SSF54826 2 125 2.57E-31 T 10-11-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4G23_RS02035 e7e347dc8ecce4ec18d5e122dc124a52 373 SMART SM00922 142 238 4.8E-23 T 10-11-2016 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal A4G23_RS02035 e7e347dc8ecce4ec18d5e122dc124a52 373 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 188 219 - T 10-11-2016 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 A4G23_RS02035 e7e347dc8ecce4ec18d5e122dc124a52 373 Gene3D G3DSA:3.20.20.120 129 358 3.6E-68 T 10-11-2016 IPR029065 Enolase C-terminal domain-like A4G23_RS02035 e7e347dc8ecce4ec18d5e122dc124a52 373 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 13 124 3.0E-19 T 10-11-2016 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain A4G23_RS02035 e7e347dc8ecce4ec18d5e122dc124a52 373 Pfam PF13378 Enolase C-terminal domain-like 145 359 6.9E-52 T 10-11-2016 IPR029065 Enolase C-terminal domain-like A4G23_RS02035 e7e347dc8ecce4ec18d5e122dc124a52 373 SUPERFAMILY SSF51604 126 358 3.14E-63 T 10-11-2016 IPR029065 Enolase C-terminal domain-like A4G23_RS02035 e7e347dc8ecce4ec18d5e122dc124a52 373 Gene3D G3DSA:3.30.390.10 2 128 2.8E-39 T 10-11-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4G23_RS15355 7041331847d5c31c7ccfedcca8fcb967 226 Gene3D G3DSA:1.10.10.10 124 219 4.2E-34 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS15355 7041331847d5c31c7ccfedcca8fcb967 226 Pfam PF00196 Bacterial regulatory proteins, luxR family 157 212 9.0E-20 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS15355 7041331847d5c31c7ccfedcca8fcb967 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 2.0E-14 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS15355 7041331847d5c31c7ccfedcca8fcb967 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 2.0E-14 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS15355 7041331847d5c31c7ccfedcca8fcb967 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 2.0E-14 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS15355 7041331847d5c31c7ccfedcca8fcb967 226 Gene3D G3DSA:3.40.50.2300 1 123 3.3E-37 T 10-11-2016 A4G23_RS15355 7041331847d5c31c7ccfedcca8fcb967 226 SUPERFAMILY SSF46894 150 218 1.02E-22 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS15355 7041331847d5c31c7ccfedcca8fcb967 226 Pfam PF00072 Response regulator receiver domain 6 117 3.9E-26 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS15355 7041331847d5c31c7ccfedcca8fcb967 226 SMART SM00421 155 212 5.5E-25 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS15355 7041331847d5c31c7ccfedcca8fcb967 226 SMART SM00448 3 116 9.1E-31 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS15355 7041331847d5c31c7ccfedcca8fcb967 226 SUPERFAMILY SSF52172 2 135 6.4E-34 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS15355 7041331847d5c31c7ccfedcca8fcb967 226 ProSitePatterns PS00622 LuxR-type HTH domain signature. 172 199 - T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS18280 3eb4c288a7ec0962d3953b6e699424ec 330 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 8 291 36.603 T 10-11-2016 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 A4G23_RS18280 3eb4c288a7ec0962d3953b6e699424ec 330 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 10 287 1.6E-96 T 10-11-2016 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 A4G23_RS18280 3eb4c288a7ec0962d3953b6e699424ec 330 Pfam PF02401 LytB protein 10 287 2.7E-88 T 10-11-2016 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 A4G23_RS08355 195883e46a49d7e1dcc020d8e0a7a429 285 SUPERFAMILY SSF46946 137 221 2.09E-25 T 10-11-2016 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 A4G23_RS08355 195883e46a49d7e1dcc020d8e0a7a429 285 Pfam PF06827 Zinc finger found in FPG and IleRS 257 284 1.3E-6 T 10-11-2016 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 A4G23_RS08355 195883e46a49d7e1dcc020d8e0a7a429 285 SUPERFAMILY SSF81624 2 139 3.14E-19 T 10-11-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 A4G23_RS08355 195883e46a49d7e1dcc020d8e0a7a429 285 Gene3D G3DSA:3.20.190.10 2 138 4.0E-13 T 10-11-2016 A4G23_RS08355 195883e46a49d7e1dcc020d8e0a7a429 285 SMART SM00898 2 124 1.4E-15 T 10-11-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 A4G23_RS08355 195883e46a49d7e1dcc020d8e0a7a429 285 ProSitePatterns PS01242 Zinc finger FPG-type signature. 259 283 - T 10-11-2016 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 A4G23_RS08355 195883e46a49d7e1dcc020d8e0a7a429 285 SMART SM01232 138 230 5.9E-33 T 10-11-2016 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 A4G23_RS08355 195883e46a49d7e1dcc020d8e0a7a429 285 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 138 222 8.6E-22 T 10-11-2016 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 A4G23_RS08355 195883e46a49d7e1dcc020d8e0a7a429 285 Gene3D G3DSA:1.10.8.50 139 284 4.1E-44 T 10-11-2016 A4G23_RS08355 195883e46a49d7e1dcc020d8e0a7a429 285 SUPERFAMILY SSF57716 236 283 1.78E-12 T 10-11-2016 A4G23_RS08355 195883e46a49d7e1dcc020d8e0a7a429 285 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 2 118 1.6E-6 T 10-11-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 A4G23_RS08250 eb11dcf22ae81fdc6198e521e96d3324 400 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 34 396 5.4E-107 T 10-11-2016 IPR011923 Rod shape-determining protein RodA GO:0008360|GO:0016021 A4G23_RS08250 eb11dcf22ae81fdc6198e521e96d3324 400 Pfam PF01098 Cell cycle protein 37 395 3.8E-94 T 10-11-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 A4G23_RS08250 eb11dcf22ae81fdc6198e521e96d3324 400 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 354 378 - T 10-11-2016 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 A4G23_RS21965 a1ba63fe488d8020c81327aeaa91b166 200 Gene3D G3DSA:1.10.357.10 8 192 3.5E-39 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS21965 a1ba63fe488d8020c81327aeaa91b166 200 SUPERFAMILY SSF48498 78 193 4.45E-20 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS21965 a1ba63fe488d8020c81327aeaa91b166 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 55 2.2E-13 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS21965 a1ba63fe488d8020c81327aeaa91b166 200 Pfam PF16925 Bacterial transcriptional repressor C-terminal 99 189 1.6E-12 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS21965 a1ba63fe488d8020c81327aeaa91b166 200 SUPERFAMILY SSF46689 4 82 1.26E-17 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS21965 a1ba63fe488d8020c81327aeaa91b166 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 3.2E-7 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS21965 a1ba63fe488d8020c81327aeaa91b166 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 3.2E-7 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS21565 4db6fc11843b5062f4ee52fd71855dc0 222 Pfam PF02080 TrkA-C domain 150 213 8.6E-11 T 10-11-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A4G23_RS21565 4db6fc11843b5062f4ee52fd71855dc0 222 SUPERFAMILY SSF116726 131 211 6.54E-9 T 10-11-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A4G23_RS21565 4db6fc11843b5062f4ee52fd71855dc0 222 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 3.9E-8 T 10-11-2016 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A4G23_RS21565 4db6fc11843b5062f4ee52fd71855dc0 222 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 3.9E-8 T 10-11-2016 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A4G23_RS21565 4db6fc11843b5062f4ee52fd71855dc0 222 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 3.9E-8 T 10-11-2016 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A4G23_RS21565 4db6fc11843b5062f4ee52fd71855dc0 222 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 3.9E-8 T 10-11-2016 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A4G23_RS21565 4db6fc11843b5062f4ee52fd71855dc0 222 Pfam PF02254 TrkA-N domain 3 116 6.7E-25 T 10-11-2016 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 A4G23_RS21565 4db6fc11843b5062f4ee52fd71855dc0 222 Gene3D G3DSA:3.30.70.1450 145 212 3.0E-6 T 10-11-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A4G23_RS21565 4db6fc11843b5062f4ee52fd71855dc0 222 SUPERFAMILY SSF51735 2 140 9.45E-29 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS21565 4db6fc11843b5062f4ee52fd71855dc0 222 Gene3D G3DSA:3.40.50.720 2 140 1.5E-33 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS15860 a153d4231d8a8fcab76e4f6602dd90c9 488 Gene3D G3DSA:3.40.50.300 243 307 8.1E-6 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS15860 a153d4231d8a8fcab76e4f6602dd90c9 488 Gene3D G3DSA:3.40.50.300 34 92 8.1E-6 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS15860 a153d4231d8a8fcab76e4f6602dd90c9 488 SUPERFAMILY SSF52540 237 324 1.33E-7 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS15860 a153d4231d8a8fcab76e4f6602dd90c9 488 SUPERFAMILY SSF52540 40 75 1.33E-7 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS15860 a153d4231d8a8fcab76e4f6602dd90c9 488 SMART SM00382 39 331 0.0016 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS25025 f3015c68cdc86cc97b440ca121bebc1a 891 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 51 103 9.7E-8 T 10-11-2016 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS25025 f3015c68cdc86cc97b440ca121bebc1a 891 Pfam PF00361 Proton-conducting membrane transporter 117 396 2.9E-66 T 10-11-2016 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS25025 f3015c68cdc86cc97b440ca121bebc1a 891 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 769 877 5.3E-20 T 10-11-2016 IPR007182 Na+/H+ antiporter MnhB subunit-related protein A4G23_RS25025 f3015c68cdc86cc97b440ca121bebc1a 891 Pfam PF13244 Domain of unknown function (DUF4040) 591 652 3.7E-10 T 10-11-2016 IPR025383 Domain of unknown function DUF4040 A4G23_RS25025 f3015c68cdc86cc97b440ca121bebc1a 891 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 205 226 1.7E-37 T 10-11-2016 A4G23_RS25025 f3015c68cdc86cc97b440ca121bebc1a 891 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 295 307 1.7E-37 T 10-11-2016 A4G23_RS25025 f3015c68cdc86cc97b440ca121bebc1a 891 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 94 114 1.7E-37 T 10-11-2016 A4G23_RS25025 f3015c68cdc86cc97b440ca121bebc1a 891 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 139 160 1.7E-37 T 10-11-2016 A4G23_RS25025 f3015c68cdc86cc97b440ca121bebc1a 891 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 66 91 1.7E-37 T 10-11-2016 A4G23_RS25025 f3015c68cdc86cc97b440ca121bebc1a 891 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 404 423 1.7E-37 T 10-11-2016 A4G23_RS25025 f3015c68cdc86cc97b440ca121bebc1a 891 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 227 253 1.7E-37 T 10-11-2016 A4G23_RS04945 b50b3bbd3d952208e97b3de7ab7b2c05 579 Pfam PF02463 RecF/RecN/SMC N terminal domain 19 532 1.6E-17 T 10-11-2016 IPR003395 RecF/RecN/SMC, N-terminal A4G23_RS04945 b50b3bbd3d952208e97b3de7ab7b2c05 579 SUPERFAMILY SSF52540 5 223 1.02E-54 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS04945 b50b3bbd3d952208e97b3de7ab7b2c05 579 Gene3D G3DSA:3.40.50.300 6 212 6.9E-58 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS04945 b50b3bbd3d952208e97b3de7ab7b2c05 579 SUPERFAMILY SSF52540 10 54 1.39E-23 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS04945 b50b3bbd3d952208e97b3de7ab7b2c05 579 SUPERFAMILY SSF52540 363 527 1.39E-23 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS04945 b50b3bbd3d952208e97b3de7ab7b2c05 579 PIRSF PIRSF003128 5 578 6.6E-154 T 10-11-2016 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 A4G23_RS04945 b50b3bbd3d952208e97b3de7ab7b2c05 579 Gene3D G3DSA:3.40.50.300 452 538 4.6E-7 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS04945 b50b3bbd3d952208e97b3de7ab7b2c05 579 TIGRFAM TIGR00634 recN: DNA repair protein RecN 5 573 2.6E-160 T 10-11-2016 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 A4G23_RS01335 d152bddb9f421e768847df35b2d7a5fd 577 PIRSF PIRSF005047 3 574 2.2E-203 T 10-11-2016 IPR022311 Uncharacterised conserved protein UCP005047, YshC KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4G23_RS01335 d152bddb9f421e768847df35b2d7a5fd 577 Gene3D G3DSA:3.30.210.10 256 317 3.3E-23 T 10-11-2016 IPR029398 DNA polymerase beta, thumb domain A4G23_RS01335 d152bddb9f421e768847df35b2d7a5fd 577 Pfam PF14791 DNA polymerase beta thumb 256 317 6.8E-21 T 10-11-2016 IPR029398 DNA polymerase beta, thumb domain A4G23_RS01335 d152bddb9f421e768847df35b2d7a5fd 577 SMART SM00278 52 71 12.0 T 10-11-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A4G23_RS01335 d152bddb9f421e768847df35b2d7a5fd 577 SMART SM00278 92 111 52.0 T 10-11-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A4G23_RS01335 d152bddb9f421e768847df35b2d7a5fd 577 SMART SM00278 127 146 34.0 T 10-11-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A4G23_RS01335 d152bddb9f421e768847df35b2d7a5fd 577 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 240 248 1.2E-7 T 10-11-2016 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4G23_RS01335 d152bddb9f421e768847df35b2d7a5fd 577 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 255 262 1.2E-7 T 10-11-2016 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4G23_RS01335 d152bddb9f421e768847df35b2d7a5fd 577 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 299 316 1.2E-7 T 10-11-2016 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4G23_RS01335 d152bddb9f421e768847df35b2d7a5fd 577 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 59 76 1.2E-7 T 10-11-2016 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4G23_RS01335 d152bddb9f421e768847df35b2d7a5fd 577 Pfam PF14716 Helix-hairpin-helix domain 5 72 3.8E-18 T 10-11-2016 IPR010996 DNA polymerase beta-like, N-terminal domain A4G23_RS01335 d152bddb9f421e768847df35b2d7a5fd 577 SMART SM00481 341 419 2.9E-12 T 10-11-2016 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 A4G23_RS01335 d152bddb9f421e768847df35b2d7a5fd 577 SUPERFAMILY SSF89550 339 574 1.27E-49 T 10-11-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A4G23_RS01335 d152bddb9f421e768847df35b2d7a5fd 577 Gene3D G3DSA:1.10.8.310 4 85 6.8E-17 T 10-11-2016 IPR027420 DNA polymerase beta, N-terminal domain A4G23_RS01335 d152bddb9f421e768847df35b2d7a5fd 577 Pfam PF02811 PHP domain 342 422 4.2E-6 T 10-11-2016 IPR004013 PHP domain GO:0003824 A4G23_RS01335 d152bddb9f421e768847df35b2d7a5fd 577 SUPERFAMILY SSF47802 5 85 5.1E-15 T 10-11-2016 IPR010996 DNA polymerase beta-like, N-terminal domain A4G23_RS01335 d152bddb9f421e768847df35b2d7a5fd 577 SMART SM00483 3 317 1.1E-16 T 10-11-2016 IPR002054 DNA-directed DNA polymerase X GO:0003677|GO:0003887 A4G23_RS01335 d152bddb9f421e768847df35b2d7a5fd 577 Gene3D G3DSA:3.20.20.140 339 572 1.1E-46 T 10-11-2016 A4G23_RS01335 d152bddb9f421e768847df35b2d7a5fd 577 SUPERFAMILY SSF81301 157 317 1.25E-40 T 10-11-2016 A4G23_RS01335 d152bddb9f421e768847df35b2d7a5fd 577 Gene3D G3DSA:3.30.460.10 164 255 3.7E-13 T 10-11-2016 A4G23_RS01335 d152bddb9f421e768847df35b2d7a5fd 577 Pfam PF14520 Helix-hairpin-helix domain 92 144 9.0E-10 T 10-11-2016 A4G23_RS01510 b48145950a151b47ad98977e674c77ce 481 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 130 289 4.1E-40 T 10-11-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4G23_RS01510 b48145950a151b47ad98977e674c77ce 481 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 287 294 - T 10-11-2016 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4G23_RS01510 b48145950a151b47ad98977e674c77ce 481 Gene3D G3DSA:3.30.360.10 298 453 8.5E-50 T 10-11-2016 A4G23_RS01510 b48145950a151b47ad98977e674c77ce 481 SUPERFAMILY SSF55347 289 452 1.22E-48 T 10-11-2016 A4G23_RS01510 b48145950a151b47ad98977e674c77ce 481 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 131 463 3.3E-111 T 10-11-2016 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4G23_RS01510 b48145950a151b47ad98977e674c77ce 481 Gene3D G3DSA:3.40.50.720 130 297 7.7E-50 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS01510 b48145950a151b47ad98977e674c77ce 481 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 310 326 8.7E-19 T 10-11-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4G23_RS01510 b48145950a151b47ad98977e674c77ce 481 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 247 260 8.7E-19 T 10-11-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4G23_RS01510 b48145950a151b47ad98977e674c77ce 481 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 366 383 8.7E-19 T 10-11-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4G23_RS01510 b48145950a151b47ad98977e674c77ce 481 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 283 301 8.7E-19 T 10-11-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4G23_RS01510 b48145950a151b47ad98977e674c77ce 481 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 294 451 3.9E-43 T 10-11-2016 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4G23_RS01510 b48145950a151b47ad98977e674c77ce 481 SMART SM00846 129 289 3.0E-52 T 10-11-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4G23_RS01510 b48145950a151b47ad98977e674c77ce 481 SUPERFAMILY SSF51735 130 305 3.35E-44 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS03585 7ca08ddb0257c76a598c46c1e47f84f0 188 Hamap MF_00141 Elongation factor P [efp]. 1 186 50.758 T 10-11-2016 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 A4G23_RS03585 7ca08ddb0257c76a598c46c1e47f84f0 188 SUPERFAMILY SSF50249 130 186 3.43E-18 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS03585 7ca08ddb0257c76a598c46c1e47f84f0 188 ProSitePatterns PS01275 Elongation factor P signature. 151 170 - T 10-11-2016 IPR013852 Translation elongation factor P/YeiP, conserved site A4G23_RS03585 7ca08ddb0257c76a598c46c1e47f84f0 188 SMART SM01185 68 122 5.0E-26 T 10-11-2016 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 A4G23_RS03585 7ca08ddb0257c76a598c46c1e47f84f0 188 Pfam PF09285 Elongation factor P, C-terminal 130 185 2.4E-26 T 10-11-2016 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 A4G23_RS03585 7ca08ddb0257c76a598c46c1e47f84f0 188 Gene3D G3DSA:2.30.30.30 3 64 2.4E-30 T 10-11-2016 IPR014722 Ribosomal protein L2 domain 2 A4G23_RS03585 7ca08ddb0257c76a598c46c1e47f84f0 188 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 61 1.5E-25 T 10-11-2016 IPR013185 Translation elongation factor, KOW-like A4G23_RS03585 7ca08ddb0257c76a598c46c1e47f84f0 188 Gene3D G3DSA:2.40.50.140 66 128 1.6E-24 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS03585 7ca08ddb0257c76a598c46c1e47f84f0 188 Pfam PF01132 Elongation factor P (EF-P) OB domain 69 122 1.1E-20 T 10-11-2016 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 A4G23_RS03585 7ca08ddb0257c76a598c46c1e47f84f0 188 TIGRFAM TIGR00038 efp: translation elongation factor P 3 186 1.1E-75 T 10-11-2016 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 A4G23_RS03585 7ca08ddb0257c76a598c46c1e47f84f0 188 SMART SM00841 130 185 6.9E-33 T 10-11-2016 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 A4G23_RS03585 7ca08ddb0257c76a598c46c1e47f84f0 188 PIRSF PIRSF005901 1 187 1.5E-67 T 10-11-2016 IPR020599 Translation elongation factor P/YeiP A4G23_RS03585 7ca08ddb0257c76a598c46c1e47f84f0 188 SUPERFAMILY SSF50249 66 127 3.6E-18 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS03585 7ca08ddb0257c76a598c46c1e47f84f0 188 Gene3D G3DSA:2.40.50.140 130 186 2.8E-28 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS03585 7ca08ddb0257c76a598c46c1e47f84f0 188 SUPERFAMILY SSF50104 2 64 1.5E-18 T 10-11-2016 IPR008991 Translation protein SH3-like domain A4G23_RS19345 e0b58e298d945ffd07ed97eb7380cef1 311 SUPERFAMILY SSF47240 38 237 1.56E-12 T 10-11-2016 IPR009078 Ferritin-like superfamily A4G23_RS19345 e0b58e298d945ffd07ed97eb7380cef1 311 Pfam PF11583 P-aminobenzoate N-oxygenase AurF 21 294 1.0E-100 T 10-11-2016 IPR025859 P-aminobenzoate N-oxygenase AurF A4G23_RS15445 e0b180017a5c307d570bf0746c8cafa4 442 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 312 424 3.2E-12 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS15445 e0b180017a5c307d570bf0746c8cafa4 442 Gene3D G3DSA:1.10.287.130 208 260 3.7E-12 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS15445 e0b180017a5c307d570bf0746c8cafa4 442 Pfam PF00672 HAMP domain 140 212 4.0E-10 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS15445 e0b180017a5c307d570bf0746c8cafa4 442 SUPERFAMILY SSF47384 199 273 2.75E-12 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS15445 e0b180017a5c307d570bf0746c8cafa4 442 Gene3D G3DSA:3.30.565.10 261 425 4.7E-22 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS15445 e0b180017a5c307d570bf0746c8cafa4 442 SMART SM00387 312 426 4.7E-23 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS15445 e0b180017a5c307d570bf0746c8cafa4 442 SMART SM00304 159 215 5.7E-7 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS15445 e0b180017a5c307d570bf0746c8cafa4 442 SMART SM00388 216 274 1.5E-12 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS15445 e0b180017a5c307d570bf0746c8cafa4 442 Pfam PF00512 His Kinase A (phospho-acceptor) domain 217 273 1.2E-10 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS15445 e0b180017a5c307d570bf0746c8cafa4 442 SUPERFAMILY SSF55874 263 428 5.37E-23 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS18395 4a7867465577e4b11fb2fc9e44301ee8 847 Gene3D G3DSA:3.30.450.20 20 128 1.9E-11 T 10-11-2016 A4G23_RS18395 4a7867465577e4b11fb2fc9e44301ee8 847 SUPERFAMILY SSF55874 742 827 3.01E-6 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS18395 4a7867465577e4b11fb2fc9e44301ee8 847 Gene3D G3DSA:3.30.450.20 130 255 1.5E-18 T 10-11-2016 A4G23_RS18395 4a7867465577e4b11fb2fc9e44301ee8 847 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 500 703 3.6E-52 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS18395 4a7867465577e4b11fb2fc9e44301ee8 847 SUPERFAMILY SSF81606 487 704 4.45E-10 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS18395 4a7867465577e4b11fb2fc9e44301ee8 847 SMART SM00331 474 703 2.5E-46 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS18395 4a7867465577e4b11fb2fc9e44301ee8 847 Gene3D G3DSA:3.30.450.40 272 451 1.3E-38 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS18395 4a7867465577e4b11fb2fc9e44301ee8 847 SMART SM00065 284 453 0.0015 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS18395 4a7867465577e4b11fb2fc9e44301ee8 847 SMART SM00091 139 205 0.001 T 10-11-2016 IPR000014 PAS domain A4G23_RS18395 4a7867465577e4b11fb2fc9e44301ee8 847 SMART SM00091 16 83 0.013 T 10-11-2016 IPR000014 PAS domain A4G23_RS18395 4a7867465577e4b11fb2fc9e44301ee8 847 Pfam PF13581 Histidine kinase-like ATPase domain 717 809 2.4E-7 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS18395 4a7867465577e4b11fb2fc9e44301ee8 847 Pfam PF08448 PAS fold 146 256 1.7E-24 T 10-11-2016 IPR013656 PAS fold-4 A4G23_RS18395 4a7867465577e4b11fb2fc9e44301ee8 847 Pfam PF08448 PAS fold 29 132 2.4E-6 T 10-11-2016 IPR013656 PAS fold-4 A4G23_RS18395 4a7867465577e4b11fb2fc9e44301ee8 847 SUPERFAMILY SSF55785 21 128 5.11E-9 T 10-11-2016 IPR000014 PAS domain A4G23_RS18395 4a7867465577e4b11fb2fc9e44301ee8 847 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 20 137 5.5E-7 T 10-11-2016 IPR000014 PAS domain A4G23_RS18395 4a7867465577e4b11fb2fc9e44301ee8 847 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 143 261 7.0E-8 T 10-11-2016 IPR000014 PAS domain A4G23_RS18395 4a7867465577e4b11fb2fc9e44301ee8 847 Pfam PF01590 GAF domain 369 443 2.0E-7 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS18395 4a7867465577e4b11fb2fc9e44301ee8 847 SUPERFAMILY SSF55781 365 456 6.54E-14 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS18395 4a7867465577e4b11fb2fc9e44301ee8 847 SUPERFAMILY SSF55785 130 253 2.36E-16 T 10-11-2016 IPR000014 PAS domain A4G23_RS17290 822d4c8ca60dc1f0a537b8e0fe73bbc5 189 Pfam PF02627 Carboxymuconolactone decarboxylase family 44 125 4.6E-19 T 10-11-2016 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A4G23_RS17290 822d4c8ca60dc1f0a537b8e0fe73bbc5 189 Gene3D G3DSA:1.20.1290.10 35 179 6.8E-48 T 10-11-2016 IPR029032 AhpD-like Reactome: R-HSA-5628897 A4G23_RS17290 822d4c8ca60dc1f0a537b8e0fe73bbc5 189 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 60 109 1.1E-18 T 10-11-2016 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A4G23_RS17290 822d4c8ca60dc1f0a537b8e0fe73bbc5 189 SUPERFAMILY SSF69118 34 176 2.06E-39 T 10-11-2016 IPR029032 AhpD-like Reactome: R-HSA-5628897 A4G23_RS11785 6c4a0ed4dc4be28ef249ec46e87005ca 185 Pfam PF05685 Putative restriction endonuclease 25 179 4.8E-22 T 10-11-2016 IPR008538 Domain of unknown function DUF820 A4G23_RS11785 6c4a0ed4dc4be28ef249ec46e87005ca 185 Gene3D G3DSA:3.90.1570.10 28 151 1.6E-15 T 10-11-2016 IPR012296 Nuclease, putative, TT1808 A4G23_RS11785 6c4a0ed4dc4be28ef249ec46e87005ca 185 SUPERFAMILY SSF52980 28 159 1.13E-15 T 10-11-2016 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A4G23_RS03620 05b3ec37840b79c3f8a6b13f8e092763 282 SUPERFAMILY SSF53223 5 108 8.63E-28 T 10-11-2016 A4G23_RS03620 05b3ec37840b79c3f8a6b13f8e092763 282 Gene3D G3DSA:3.40.192.10 5 113 1.1E-37 T 10-11-2016 A4G23_RS03620 05b3ec37840b79c3f8a6b13f8e092763 282 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 13 95 1.1E-24 T 10-11-2016 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 A4G23_RS03620 05b3ec37840b79c3f8a6b13f8e092763 282 SUPERFAMILY SSF51735 109 264 1.78E-20 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS03620 05b3ec37840b79c3f8a6b13f8e092763 282 Gene3D G3DSA:3.40.50.720 114 275 3.8E-31 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS23465 4ee7a4ccebeb06c3a9e33796b1487bc5 342 SUPERFAMILY SSF141986 198 330 1.31E-20 T 10-11-2016 IPR027461 LD-carboxypeptidase A, C-terminal domain A4G23_RS23465 4ee7a4ccebeb06c3a9e33796b1487bc5 342 Pfam PF02016 LD-carboxypeptidase 15 328 2.1E-65 T 10-11-2016 IPR003507 Peptidase family S66 A4G23_RS23465 4ee7a4ccebeb06c3a9e33796b1487bc5 342 Gene3D G3DSA:3.40.50.10740 1 164 1.1E-35 T 10-11-2016 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal domain A4G23_RS23465 4ee7a4ccebeb06c3a9e33796b1487bc5 342 SUPERFAMILY SSF52317 2 156 2.24E-34 T 10-11-2016 IPR029062 Class I glutamine amidotransferase-like A4G23_RS23465 4ee7a4ccebeb06c3a9e33796b1487bc5 342 PIRSF PIRSF028757 3 341 8.8E-49 T 10-11-2016 IPR003507 Peptidase family S66 A4G23_RS23465 4ee7a4ccebeb06c3a9e33796b1487bc5 342 Gene3D G3DSA:3.50.30.60 206 332 8.3E-21 T 10-11-2016 IPR027461 LD-carboxypeptidase A, C-terminal domain A4G23_RS09645 b0d9dd60c8c139bd9fedac13655c95c4 574 Gene3D G3DSA:3.20.20.80 164 553 9.7E-133 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS09645 b0d9dd60c8c139bd9fedac13655c95c4 574 PRINTS PR00738 Glycosyl hydrolase family 20 signature 260 277 5.9E-33 T 10-11-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A4G23_RS09645 b0d9dd60c8c139bd9fedac13655c95c4 574 PRINTS PR00738 Glycosyl hydrolase family 20 signature 480 496 5.9E-33 T 10-11-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A4G23_RS09645 b0d9dd60c8c139bd9fedac13655c95c4 574 PRINTS PR00738 Glycosyl hydrolase family 20 signature 498 515 5.9E-33 T 10-11-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A4G23_RS09645 b0d9dd60c8c139bd9fedac13655c95c4 574 PRINTS PR00738 Glycosyl hydrolase family 20 signature 116 136 5.9E-33 T 10-11-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A4G23_RS09645 b0d9dd60c8c139bd9fedac13655c95c4 574 PRINTS PR00738 Glycosyl hydrolase family 20 signature 189 210 5.9E-33 T 10-11-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A4G23_RS09645 b0d9dd60c8c139bd9fedac13655c95c4 574 PRINTS PR00738 Glycosyl hydrolase family 20 signature 311 329 5.9E-33 T 10-11-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A4G23_RS09645 b0d9dd60c8c139bd9fedac13655c95c4 574 PRINTS PR00738 Glycosyl hydrolase family 20 signature 336 349 5.9E-33 T 10-11-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A4G23_RS09645 b0d9dd60c8c139bd9fedac13655c95c4 574 SUPERFAMILY SSF51445 166 533 2.91E-115 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS09645 b0d9dd60c8c139bd9fedac13655c95c4 574 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 166 516 2.4E-114 T 10-11-2016 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 A4G23_RS09645 b0d9dd60c8c139bd9fedac13655c95c4 574 SUPERFAMILY SSF55545 3 60 1.05E-14 T 10-11-2016 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A4G23_RS09645 b0d9dd60c8c139bd9fedac13655c95c4 574 SUPERFAMILY SSF55545 91 165 1.05E-14 T 10-11-2016 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A4G23_RS09645 b0d9dd60c8c139bd9fedac13655c95c4 574 Gene3D G3DSA:3.30.379.10 88 162 2.1E-20 T 10-11-2016 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A4G23_RS09645 b0d9dd60c8c139bd9fedac13655c95c4 574 Gene3D G3DSA:3.30.379.10 2 55 2.1E-20 T 10-11-2016 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A4G23_RS09645 b0d9dd60c8c139bd9fedac13655c95c4 574 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 2 144 5.9E-15 T 10-11-2016 IPR015882 Beta-hexosaminidase, bacteial type, N-terminal KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 A4G23_RS07685 b24db0a0fe7d113454831139d2e64764 643 SUPERFAMILY SSF56731 117 428 1.41E-93 T 10-11-2016 A4G23_RS07685 b24db0a0fe7d113454831139d2e64764 643 Gene3D G3DSA:3.90.980.10 117 241 1.5E-38 T 10-11-2016 IPR013264 DNA primase, catalytic core, N-terminal A4G23_RS07685 b24db0a0fe7d113454831139d2e64764 643 Pfam PF08275 DNA primase catalytic core, N-terminal domain 127 253 3.9E-36 T 10-11-2016 IPR013264 DNA primase, catalytic core, N-terminal A4G23_RS07685 b24db0a0fe7d113454831139d2e64764 643 Gene3D G3DSA:3.90.580.10 3 102 1.0E-34 T 10-11-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 A4G23_RS07685 b24db0a0fe7d113454831139d2e64764 643 Pfam PF08278 DNA primase DnaG DnaB-binding 494 609 6.8E-14 T 10-11-2016 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 A4G23_RS07685 b24db0a0fe7d113454831139d2e64764 643 Pfam PF13662 Toprim domain 262 332 4.8E-16 T 10-11-2016 IPR006171 Toprim domain A4G23_RS07685 b24db0a0fe7d113454831139d2e64764 643 SMART SM00766 493 622 1.9E-15 T 10-11-2016 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 A4G23_RS07685 b24db0a0fe7d113454831139d2e64764 643 SMART SM00493 261 337 3.5E-16 T 10-11-2016 IPR006171 Toprim domain A4G23_RS07685 b24db0a0fe7d113454831139d2e64764 643 TIGRFAM TIGR01391 dnaG: DNA primase 5 420 1.7E-112 T 10-11-2016 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 A4G23_RS07685 b24db0a0fe7d113454831139d2e64764 643 Pfam PF10410 DnaB-helicase binding domain of primase 373 426 5.1E-13 T 10-11-2016 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 A4G23_RS07685 b24db0a0fe7d113454831139d2e64764 643 PIRSF PIRSF002811 2 633 5.6E-166 T 10-11-2016 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 A4G23_RS07685 b24db0a0fe7d113454831139d2e64764 643 Hamap MF_00974 DNA primase [dnaG]. 4 627 26.448 T 10-11-2016 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 A4G23_RS07685 b24db0a0fe7d113454831139d2e64764 643 SUPERFAMILY SSF57783 4 102 7.82E-31 T 10-11-2016 A4G23_RS07685 b24db0a0fe7d113454831139d2e64764 643 Pfam PF01807 CHC2 zinc finger 7 101 1.5E-31 T 10-11-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 A4G23_RS07685 b24db0a0fe7d113454831139d2e64764 643 Gene3D G3DSA:1.20.50.20 372 429 5.6E-9 T 10-11-2016 A4G23_RS07685 b24db0a0fe7d113454831139d2e64764 643 SMART SM00400 37 91 1.1E-33 T 10-11-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 A4G23_RS07685 b24db0a0fe7d113454831139d2e64764 643 Gene3D G3DSA:3.40.1360.10 243 368 2.4E-40 T 10-11-2016 A4G23_RS21660 6ba692ce45a68db35372a5bbc40daaa9 1073 Pfam PF00550 Phosphopantetheine attachment site 575 638 3.2E-13 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS21660 6ba692ce45a68db35372a5bbc40daaa9 1073 Gene3D G3DSA:3.40.50.980 227 379 1.7E-38 T 10-11-2016 A4G23_RS21660 6ba692ce45a68db35372a5bbc40daaa9 1073 Gene3D G3DSA:1.10.1200.10 579 644 1.0E-19 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS21660 6ba692ce45a68db35372a5bbc40daaa9 1073 Gene3D G3DSA:3.30.300.30 458 578 8.8E-30 T 10-11-2016 A4G23_RS21660 6ba692ce45a68db35372a5bbc40daaa9 1073 SUPERFAMILY SSF47336 570 639 9.68E-16 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS21660 6ba692ce45a68db35372a5bbc40daaa9 1073 Gene3D G3DSA:2.30.38.10 380 452 7.6E-26 T 10-11-2016 A4G23_RS21660 6ba692ce45a68db35372a5bbc40daaa9 1073 Gene3D G3DSA:3.40.50.980 34 150 2.9E-34 T 10-11-2016 A4G23_RS21660 6ba692ce45a68db35372a5bbc40daaa9 1073 Gene3D G3DSA:3.40.50.980 189 226 2.9E-34 T 10-11-2016 A4G23_RS21660 6ba692ce45a68db35372a5bbc40daaa9 1073 Pfam PF00668 Condensation domain 659 950 6.3E-31 T 10-11-2016 IPR001242 Condensation domain A4G23_RS21660 6ba692ce45a68db35372a5bbc40daaa9 1073 SUPERFAMILY SSF56801 33 587 1.96E-132 T 10-11-2016 A4G23_RS21660 6ba692ce45a68db35372a5bbc40daaa9 1073 SUPERFAMILY SSF52777 658 852 9.45E-30 T 10-11-2016 A4G23_RS21660 6ba692ce45a68db35372a5bbc40daaa9 1073 Pfam PF13193 AMP-binding enzyme C-terminal domain 471 544 2.2E-11 T 10-11-2016 IPR025110 AMP-binding enzyme C-terminal domain A4G23_RS21660 6ba692ce45a68db35372a5bbc40daaa9 1073 SMART SM00823 Phosphopantetheine attachment site 574 642 9.6E-8 T 10-11-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4G23_RS21660 6ba692ce45a68db35372a5bbc40daaa9 1073 Pfam PF00501 AMP-binding enzyme 43 463 7.0E-80 T 10-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A4G23_RS21660 6ba692ce45a68db35372a5bbc40daaa9 1073 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 62 486 3.9E-115 T 10-11-2016 IPR010071 Amino acid adenylation domain A4G23_RS21660 6ba692ce45a68db35372a5bbc40daaa9 1073 SUPERFAMILY SSF52777 848 1071 5.89E-29 T 10-11-2016 A4G23_RS06575 2f513d6039ecf4ad868c41a8cc858d5c 322 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 228 276 - T 10-11-2016 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS06575 2f513d6039ecf4ad868c41a8cc858d5c 322 Gene3D G3DSA:2.60.40.420 138 294 5.6E-40 T 10-11-2016 IPR008972 Cupredoxin A4G23_RS06575 2f513d6039ecf4ad868c41a8cc858d5c 322 Gene3D G3DSA:1.10.287.90 43 126 6.6E-14 T 10-11-2016 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS06575 2f513d6039ecf4ad868c41a8cc858d5c 322 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 54 291 5.3E-46 T 10-11-2016 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS06575 2f513d6039ecf4ad868c41a8cc858d5c 322 SUPERFAMILY SSF49503 135 159 6.2E-40 T 10-11-2016 IPR008972 Cupredoxin A4G23_RS06575 2f513d6039ecf4ad868c41a8cc858d5c 322 SUPERFAMILY SSF49503 205 301 6.2E-40 T 10-11-2016 IPR008972 Cupredoxin A4G23_RS06575 2f513d6039ecf4ad868c41a8cc858d5c 322 PRINTS PR01166 Cytochrome c oxidase subunit II signature 227 247 6.4E-14 T 10-11-2016 A4G23_RS06575 2f513d6039ecf4ad868c41a8cc858d5c 322 PRINTS PR01166 Cytochrome c oxidase subunit II signature 247 264 6.4E-14 T 10-11-2016 A4G23_RS06575 2f513d6039ecf4ad868c41a8cc858d5c 322 PRINTS PR01166 Cytochrome c oxidase subunit II signature 101 113 6.4E-14 T 10-11-2016 A4G23_RS06575 2f513d6039ecf4ad868c41a8cc858d5c 322 PRINTS PR01166 Cytochrome c oxidase subunit II signature 136 155 6.4E-14 T 10-11-2016 A4G23_RS06575 2f513d6039ecf4ad868c41a8cc858d5c 322 PRINTS PR01166 Cytochrome c oxidase subunit II signature 265 282 6.4E-14 T 10-11-2016 A4G23_RS06575 2f513d6039ecf4ad868c41a8cc858d5c 322 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 211 282 1.4E-17 T 10-11-2016 IPR002429 Cytochrome c oxidase subunit II C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS06575 2f513d6039ecf4ad868c41a8cc858d5c 322 SUPERFAMILY SSF81464 37 126 4.91E-17 T 10-11-2016 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS25720 57f478efcf4559013b9e268ab4467e99 681 SUPERFAMILY SSF81606 348 549 3.92E-12 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS25720 57f478efcf4559013b9e268ab4467e99 681 SMART SM00331 334 550 3.5E-32 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS25720 57f478efcf4559013b9e268ab4467e99 681 SUPERFAMILY SSF55781 181 319 2.84E-15 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS25720 57f478efcf4559013b9e268ab4467e99 681 Gene3D G3DSA:3.60.40.10 476 548 2.6E-5 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS25720 57f478efcf4559013b9e268ab4467e99 681 Gene3D G3DSA:3.30.450.20 28 131 9.9E-15 T 10-11-2016 A4G23_RS25720 57f478efcf4559013b9e268ab4467e99 681 Pfam PF13581 Histidine kinase-like ATPase domain 569 679 5.6E-12 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS25720 57f478efcf4559013b9e268ab4467e99 681 SUPERFAMILY SSF55785 28 132 3.32E-13 T 10-11-2016 IPR000014 PAS domain A4G23_RS25720 57f478efcf4559013b9e268ab4467e99 681 SMART SM00065 163 316 9.5E-5 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS25720 57f478efcf4559013b9e268ab4467e99 681 Gene3D G3DSA:3.30.450.40 145 320 2.6E-14 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS25720 57f478efcf4559013b9e268ab4467e99 681 Pfam PF08447 PAS fold 40 128 2.1E-12 T 10-11-2016 IPR013655 PAS fold-3 GO:0005515 A4G23_RS25720 57f478efcf4559013b9e268ab4467e99 681 SUPERFAMILY SSF55874 590 679 1.18E-7 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS25720 57f478efcf4559013b9e268ab4467e99 681 Pfam PF13185 GAF domain 165 306 2.9E-12 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS25720 57f478efcf4559013b9e268ab4467e99 681 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 363 550 1.2E-45 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS17310 a230594200125db1cdfc1bd6970f2b71 402 SUPERFAMILY SSF53383 4 399 1.06E-119 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS17310 a230594200125db1cdfc1bd6970f2b71 402 Pfam PF00202 Aminotransferase class-III 16 399 1.0E-111 T 10-11-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4G23_RS17310 a230594200125db1cdfc1bd6970f2b71 402 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 223 260 - T 10-11-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4G23_RS17310 a230594200125db1cdfc1bd6970f2b71 402 TIGRFAM TIGR01885 Orn_aminotrans: ornithine--oxo-acid transaminase 4 399 3.2E-143 T 10-11-2016 IPR010164 Ornithine aminotransferase GO:0008483|GO:0030170 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A4G23_RS17310 a230594200125db1cdfc1bd6970f2b71 402 Gene3D G3DSA:3.90.1150.10 292 400 7.8E-37 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS17310 a230594200125db1cdfc1bd6970f2b71 402 Gene3D G3DSA:3.40.640.10 60 291 3.7E-81 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS00275 d6d4da7beb5f16a939a735c6fbb06d13 283 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 55 279 3.1E-91 T 10-11-2016 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS00275 d6d4da7beb5f16a939a735c6fbb06d13 283 PRINTS PR00046 Major sigma-70 factor signature 232 244 5.4E-10 T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS00275 d6d4da7beb5f16a939a735c6fbb06d13 283 PRINTS PR00046 Major sigma-70 factor signature 249 264 5.4E-10 T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS00275 d6d4da7beb5f16a939a735c6fbb06d13 283 PRINTS PR00046 Major sigma-70 factor signature 85 98 5.4E-10 T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS00275 d6d4da7beb5f16a939a735c6fbb06d13 283 PRINTS PR00046 Major sigma-70 factor signature 264 275 5.4E-10 T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS00275 d6d4da7beb5f16a939a735c6fbb06d13 283 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 57 278 1.3E-33 T 10-11-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS00275 d6d4da7beb5f16a939a735c6fbb06d13 283 Pfam PF04539 Sigma-70 region 3 140 207 9.9E-14 T 10-11-2016 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS00275 d6d4da7beb5f16a939a735c6fbb06d13 283 Pfam PF04542 Sigma-70 region 2 61 130 1.1E-16 T 10-11-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS00275 d6d4da7beb5f16a939a735c6fbb06d13 283 SUPERFAMILY SSF88659 134 210 2.66E-15 T 10-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS00275 d6d4da7beb5f16a939a735c6fbb06d13 283 Gene3D G3DSA:1.10.601.10 47 128 8.5E-26 T 10-11-2016 A4G23_RS00275 d6d4da7beb5f16a939a735c6fbb06d13 283 Pfam PF04545 Sigma-70, region 4 229 277 2.2E-16 T 10-11-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS00275 d6d4da7beb5f16a939a735c6fbb06d13 283 SUPERFAMILY SSF88946 24 130 3.01E-32 T 10-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS00275 d6d4da7beb5f16a939a735c6fbb06d13 283 Gene3D G3DSA:1.10.10.10 129 184 9.3E-19 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS00275 d6d4da7beb5f16a939a735c6fbb06d13 283 SUPERFAMILY SSF88659 197 279 2.62E-17 T 10-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS00275 d6d4da7beb5f16a939a735c6fbb06d13 283 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 85 98 - T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS00275 d6d4da7beb5f16a939a735c6fbb06d13 283 Gene3D G3DSA:1.10.10.10 222 278 4.1E-11 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS13860 b37bd7e40131631bdd60d35ffcb2a078 550 Gene3D G3DSA:2.40.10.10 228 332 2.8E-27 T 10-11-2016 A4G23_RS13860 b37bd7e40131631bdd60d35ffcb2a078 550 Pfam PF13180 PDZ domain 455 544 3.0E-24 T 10-11-2016 IPR001478 PDZ domain GO:0005515 A4G23_RS13860 b37bd7e40131631bdd60d35ffcb2a078 550 Pfam PF13365 Trypsin-like peptidase domain 263 408 5.0E-35 T 10-11-2016 A4G23_RS13860 b37bd7e40131631bdd60d35ffcb2a078 550 SUPERFAMILY SSF50156 436 544 5.52E-17 T 10-11-2016 IPR001478 PDZ domain GO:0005515 A4G23_RS13860 b37bd7e40131631bdd60d35ffcb2a078 550 Gene3D G3DSA:2.40.10.10 333 457 3.3E-41 T 10-11-2016 A4G23_RS13860 b37bd7e40131631bdd60d35ffcb2a078 550 PRINTS PR00834 HtrA/DegQ protease family signature 401 418 3.0E-45 T 10-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4G23_RS13860 b37bd7e40131631bdd60d35ffcb2a078 550 PRINTS PR00834 HtrA/DegQ protease family signature 379 396 3.0E-45 T 10-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4G23_RS13860 b37bd7e40131631bdd60d35ffcb2a078 550 PRINTS PR00834 HtrA/DegQ protease family signature 493 505 3.0E-45 T 10-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4G23_RS13860 b37bd7e40131631bdd60d35ffcb2a078 550 PRINTS PR00834 HtrA/DegQ protease family signature 296 316 3.0E-45 T 10-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4G23_RS13860 b37bd7e40131631bdd60d35ffcb2a078 550 PRINTS PR00834 HtrA/DegQ protease family signature 272 284 3.0E-45 T 10-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4G23_RS13860 b37bd7e40131631bdd60d35ffcb2a078 550 PRINTS PR00834 HtrA/DegQ protease family signature 338 362 3.0E-45 T 10-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4G23_RS13860 b37bd7e40131631bdd60d35ffcb2a078 550 SMART SM00228 466 535 2.9E-4 T 10-11-2016 IPR001478 PDZ domain GO:0005515 A4G23_RS13860 b37bd7e40131631bdd60d35ffcb2a078 550 Gene3D G3DSA:2.30.42.10 458 549 4.1E-19 T 10-11-2016 IPR001478 PDZ domain GO:0005515 A4G23_RS13860 b37bd7e40131631bdd60d35ffcb2a078 550 SUPERFAMILY SSF50494 235 448 1.04E-56 T 10-11-2016 IPR009003 Peptidase S1, PA clan A4G23_RS03240 4932347677e559a2e082d5c9d791f4a6 501 SUPERFAMILY SSF53383 119 480 2.56E-71 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS03240 4932347677e559a2e082d5c9d791f4a6 501 Pfam PF00392 Bacterial regulatory proteins, gntR family 35 94 1.1E-11 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS03240 4932347677e559a2e082d5c9d791f4a6 501 Pfam PF00155 Aminotransferase class I and II 159 463 2.4E-29 T 10-11-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4G23_RS03240 4932347677e559a2e082d5c9d791f4a6 501 SMART SM00345 38 99 1.0E-7 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS03240 4932347677e559a2e082d5c9d791f4a6 501 Gene3D G3DSA:3.90.1150.10 349 480 1.5E-16 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS03240 4932347677e559a2e082d5c9d791f4a6 501 Gene3D G3DSA:3.40.640.10 151 348 9.8E-42 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS03240 4932347677e559a2e082d5c9d791f4a6 501 SUPERFAMILY SSF46785 31 101 9.93E-15 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS03240 4932347677e559a2e082d5c9d791f4a6 501 Gene3D G3DSA:1.10.10.10 33 95 3.3E-18 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS03240 4932347677e559a2e082d5c9d791f4a6 501 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 57 71 1.3E-7 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS03240 4932347677e559a2e082d5c9d791f4a6 501 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 71 87 1.3E-7 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS19955 1e6321c4c2669f6aede319d0cb8bac99 371 Pfam PF01571 Aminomethyltransferase folate-binding domain 11 260 1.6E-91 T 10-11-2016 IPR006222 Glycine cleavage T-protein-like, N-terminal A4G23_RS19955 1e6321c4c2669f6aede319d0cb8bac99 371 Gene3D G3DSA:3.30.70.1400 56 143 1.1E-27 T 10-11-2016 A4G23_RS19955 1e6321c4c2669f6aede319d0cb8bac99 371 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 268 363 1.3E-23 T 10-11-2016 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 A4G23_RS19955 1e6321c4c2669f6aede319d0cb8bac99 371 Hamap MF_00259 Aminomethyltransferase [gcvT]. 4 369 44.55 T 10-11-2016 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 A4G23_RS19955 1e6321c4c2669f6aede319d0cb8bac99 371 SUPERFAMILY SSF101790 283 370 8.83E-24 T 10-11-2016 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain A4G23_RS19955 1e6321c4c2669f6aede319d0cb8bac99 371 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 6 369 1.0E-104 T 10-11-2016 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 A4G23_RS19955 1e6321c4c2669f6aede319d0cb8bac99 371 Gene3D G3DSA:3.30.1360.120 144 238 5.2E-53 T 10-11-2016 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 A4G23_RS19955 1e6321c4c2669f6aede319d0cb8bac99 371 Gene3D G3DSA:3.30.1360.120 6 55 5.2E-53 T 10-11-2016 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 A4G23_RS19955 1e6321c4c2669f6aede319d0cb8bac99 371 SUPERFAMILY SSF103025 5 281 2.83E-96 T 10-11-2016 A4G23_RS19955 1e6321c4c2669f6aede319d0cb8bac99 371 PIRSF PIRSF006487 1 371 1.1E-95 T 10-11-2016 IPR028896 Aminomethyltransferase/Dimethylsulfonioproprionate demethylase DmdA KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 A4G23_RS19955 1e6321c4c2669f6aede319d0cb8bac99 371 Gene3D G3DSA:2.40.30.110 288 363 6.3E-28 T 10-11-2016 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 A4G23_RS26015 da98e51716c9d74e7e300ffe514891e7 122 SUPERFAMILY SSF51182 9 111 1.45E-14 T 10-11-2016 IPR011051 RmlC-like cupin domain A4G23_RS26015 da98e51716c9d74e7e300ffe514891e7 122 Pfam PF07883 Cupin domain 63 111 5.0E-8 T 10-11-2016 IPR013096 Cupin 2, conserved barrel A4G23_RS26015 da98e51716c9d74e7e300ffe514891e7 122 Gene3D G3DSA:2.60.120.10 14 111 4.7E-15 T 10-11-2016 IPR014710 RmlC-like jelly roll fold A4G23_RS08565 e049232a416e77d5ef327ef66e9675fa 527 Gene3D G3DSA:3.40.50.300 147 225 2.4E-10 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS08565 e049232a416e77d5ef327ef66e9675fa 527 Gene3D G3DSA:3.40.50.300 58 103 2.4E-10 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS08565 e049232a416e77d5ef327ef66e9675fa 527 SUPERFAMILY SSF52540 39 242 3.08E-18 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS08565 e049232a416e77d5ef327ef66e9675fa 527 Pfam PF00350 Dynamin family 62 187 7.5E-8 T 10-11-2016 IPR022812 Dynamin superfamily A4G23_RS15535 c656b7f09a3eef04ac2909a99b26956a 202 SUPERFAMILY SSF52499 13 199 5.76E-39 T 10-11-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 A4G23_RS15535 c656b7f09a3eef04ac2909a99b26956a 202 Gene3D G3DSA:3.40.50.850 13 200 2.3E-42 T 10-11-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 A4G23_RS15535 c656b7f09a3eef04ac2909a99b26956a 202 Pfam PF00857 Isochorismatase family 16 162 4.6E-27 T 10-11-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 A4G23_RS08990 d70cd324c301cd2db01b3905f476fdfb 290 SUPERFAMILY SSF63380 4 144 8.51E-9 T 10-11-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 A4G23_RS08990 d70cd324c301cd2db01b3905f476fdfb 290 Gene3D G3DSA:2.40.30.10 11 144 6.3E-32 T 10-11-2016 A4G23_RS08990 d70cd324c301cd2db01b3905f476fdfb 290 Pfam PF04954 Siderophore-interacting protein 159 274 1.1E-35 T 10-11-2016 IPR007037 Siderophore-interacting protein A4G23_RS08990 d70cd324c301cd2db01b3905f476fdfb 290 Gene3D G3DSA:3.40.50.80 154 282 7.7E-46 T 10-11-2016 A4G23_RS08990 d70cd324c301cd2db01b3905f476fdfb 290 Pfam PF08021 Siderophore-interacting FAD-binding domain 18 146 2.0E-33 T 10-11-2016 IPR013113 FAD-binding 9, siderophore-interacting A4G23_RS09250 4f5b5de7aa86fef1d210828ec9628b2e 284 SUPERFAMILY SSF53850 37 268 2.09E-44 T 10-11-2016 A4G23_RS09250 4f5b5de7aa86fef1d210828ec9628b2e 284 SMART SM00062 41 271 4.2E-34 T 10-11-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A4G23_RS09250 4f5b5de7aa86fef1d210828ec9628b2e 284 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 42 267 4.1E-42 T 10-11-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A4G23_RS09250 4f5b5de7aa86fef1d210828ec9628b2e 284 Gene3D G3DSA:3.40.190.10 230 268 1.6E-25 T 10-11-2016 A4G23_RS09250 4f5b5de7aa86fef1d210828ec9628b2e 284 Gene3D G3DSA:3.40.190.10 38 118 1.6E-25 T 10-11-2016 A4G23_RS09250 4f5b5de7aa86fef1d210828ec9628b2e 284 TIGRFAM TIGR02995 ectoine_ehuB: ectoine/hydroxyectoine ABC transporter solute-binding protein EhuB 30 283 9.8E-74 T 10-11-2016 IPR014337 Ectoine/Hydroxyectoine-binding protein EhuB GO:0005886|GO:0033294|GO:0051470|GO:0051471 A4G23_RS09250 4f5b5de7aa86fef1d210828ec9628b2e 284 Gene3D G3DSA:3.40.190.10 119 211 7.4E-9 T 10-11-2016 A4G23_RS25520 85c02b97c46d77ee2f64115b8cebbd57 296 Pfam PF00582 Universal stress protein family 151 288 3.0E-21 T 10-11-2016 IPR006016 UspA GO:0006950 A4G23_RS25520 85c02b97c46d77ee2f64115b8cebbd57 296 Pfam PF00582 Universal stress protein family 3 139 1.2E-22 T 10-11-2016 IPR006016 UspA GO:0006950 A4G23_RS25520 85c02b97c46d77ee2f64115b8cebbd57 296 PRINTS PR01438 Universal stress protein signature 2 20 2.0E-12 T 10-11-2016 IPR006015 Universal stress protein A A4G23_RS25520 85c02b97c46d77ee2f64115b8cebbd57 296 PRINTS PR01438 Universal stress protein signature 248 260 2.0E-12 T 10-11-2016 IPR006015 Universal stress protein A A4G23_RS25520 85c02b97c46d77ee2f64115b8cebbd57 296 PRINTS PR01438 Universal stress protein signature 266 288 2.0E-12 T 10-11-2016 IPR006015 Universal stress protein A A4G23_RS25520 85c02b97c46d77ee2f64115b8cebbd57 296 Gene3D G3DSA:3.40.50.620 1 133 3.7E-26 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS25520 85c02b97c46d77ee2f64115b8cebbd57 296 Gene3D G3DSA:3.40.50.620 134 288 1.0E-25 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS25520 85c02b97c46d77ee2f64115b8cebbd57 296 SUPERFAMILY SSF52402 4 141 1.34E-24 T 10-11-2016 A4G23_RS25520 85c02b97c46d77ee2f64115b8cebbd57 296 SUPERFAMILY SSF52402 151 293 3.43E-20 T 10-11-2016 A4G23_RS15505 280983f72c412c0d34c3440ce8fef36e 276 SUPERFAMILY SSF51658 11 268 5.76E-46 T 10-11-2016 IPR013022 Xylose isomerase-like, TIM barrel domain A4G23_RS15505 280983f72c412c0d34c3440ce8fef36e 276 Gene3D G3DSA:3.20.20.150 13 269 2.7E-49 T 10-11-2016 IPR013022 Xylose isomerase-like, TIM barrel domain A4G23_RS15505 280983f72c412c0d34c3440ce8fef36e 276 Pfam PF01261 Xylose isomerase-like TIM barrel 33 220 1.1E-16 T 10-11-2016 IPR013022 Xylose isomerase-like, TIM barrel domain A4G23_RS12900 3bc79e7d8ff5a6de9a1d30ae2ea8f78b 226 PIRSF PIRSF001586 1 226 2.7E-83 T 10-11-2016 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A4G23_RS12900 3bc79e7d8ff5a6de9a1d30ae2ea8f78b 226 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 4 222 1.5E-82 T 10-11-2016 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A4G23_RS12900 3bc79e7d8ff5a6de9a1d30ae2ea8f78b 226 Gene3D G3DSA:3.40.50.880 4 221 3.7E-39 T 10-11-2016 IPR029062 Class I glutamine amidotransferase-like A4G23_RS12900 3bc79e7d8ff5a6de9a1d30ae2ea8f78b 226 SUPERFAMILY SSF52317 4 221 1.58E-68 T 10-11-2016 IPR029062 Class I glutamine amidotransferase-like A4G23_RS12900 3bc79e7d8ff5a6de9a1d30ae2ea8f78b 226 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 4 203 4.6E-34 T 10-11-2016 A4G23_RS12900 3bc79e7d8ff5a6de9a1d30ae2ea8f78b 226 SMART SM01211 3 223 6.7E-122 T 10-11-2016 A4G23_RS12900 3bc79e7d8ff5a6de9a1d30ae2ea8f78b 226 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 3 221 40.165 T 10-11-2016 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A4G23_RS21165 4a691e147c610918478390a6adf7fab7 222 Gene3D G3DSA:3.40.50.2300 1 153 1.5E-39 T 10-11-2016 A4G23_RS21165 4a691e147c610918478390a6adf7fab7 222 Gene3D G3DSA:1.10.10.10 154 215 1.3E-29 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS21165 4a691e147c610918478390a6adf7fab7 222 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 210 1.6E-18 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS21165 4a691e147c610918478390a6adf7fab7 222 Pfam PF00072 Response regulator receiver domain 4 115 2.1E-26 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS21165 4a691e147c610918478390a6adf7fab7 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 6.7E-13 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS21165 4a691e147c610918478390a6adf7fab7 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 6.7E-13 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS21165 4a691e147c610918478390a6adf7fab7 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 6.7E-13 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS21165 4a691e147c610918478390a6adf7fab7 222 SMART SM00421 153 210 8.5E-26 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS21165 4a691e147c610918478390a6adf7fab7 222 SMART SM00448 2 117 5.2E-29 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS21165 4a691e147c610918478390a6adf7fab7 222 SUPERFAMILY SSF46894 140 216 9.86E-23 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS21165 4a691e147c610918478390a6adf7fab7 222 SUPERFAMILY SSF52172 1 128 1.25E-32 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS06950 e88df912bf6a8bbf1531cfeaa0e37836 563 Gene3D G3DSA:1.20.1250.20 300 457 1.9E-26 T 10-11-2016 A4G23_RS06950 e88df912bf6a8bbf1531cfeaa0e37836 563 Gene3D G3DSA:1.20.1250.20 509 539 1.9E-26 T 10-11-2016 A4G23_RS06950 e88df912bf6a8bbf1531cfeaa0e37836 563 Gene3D G3DSA:1.20.1250.20 37 232 2.6E-30 T 10-11-2016 A4G23_RS06950 e88df912bf6a8bbf1531cfeaa0e37836 563 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 47 479 4.9E-75 T 10-11-2016 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 A4G23_RS06950 e88df912bf6a8bbf1531cfeaa0e37836 563 SUPERFAMILY SSF103473 33 233 3.27E-72 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS06950 e88df912bf6a8bbf1531cfeaa0e37836 563 SUPERFAMILY SSF103473 285 456 3.27E-72 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS06950 e88df912bf6a8bbf1531cfeaa0e37836 563 SUPERFAMILY SSF103473 507 537 3.27E-72 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS06950 e88df912bf6a8bbf1531cfeaa0e37836 563 PRINTS PR01036 Tetracycline resistance protein TetB signature 144 164 2.2E-7 T 10-11-2016 A4G23_RS06950 e88df912bf6a8bbf1531cfeaa0e37836 563 PRINTS PR01036 Tetracycline resistance protein TetB signature 49 73 2.2E-7 T 10-11-2016 A4G23_RS06950 e88df912bf6a8bbf1531cfeaa0e37836 563 PRINTS PR01036 Tetracycline resistance protein TetB signature 174 198 2.2E-7 T 10-11-2016 A4G23_RS06950 e88df912bf6a8bbf1531cfeaa0e37836 563 PRINTS PR01036 Tetracycline resistance protein TetB signature 437 456 2.2E-7 T 10-11-2016 A4G23_RS06950 e88df912bf6a8bbf1531cfeaa0e37836 563 Pfam PF07690 Major Facilitator Superfamily 50 446 1.1E-52 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS26165 50187731432f76c7c40226bf279a0b26 407 Pfam PF09992 Phosphodiester glycosidase 227 404 1.0E-23 T 10-11-2016 IPR018711 Phosphodiester glycosidase A4G23_RS15290 755a5b8b91e1d200a52fc2a546b86a2c 119 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 2 116 4.7E-36 T 10-11-2016 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 A4G23_RS15290 755a5b8b91e1d200a52fc2a546b86a2c 119 Pfam PF02152 Dihydroneopterin aldolase 5 115 5.1E-36 T 10-11-2016 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 A4G23_RS15290 755a5b8b91e1d200a52fc2a546b86a2c 119 TIGRFAM TIGR00526 folB_dom: FolB domain 2 118 9.2E-32 T 10-11-2016 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 A4G23_RS15290 755a5b8b91e1d200a52fc2a546b86a2c 119 SUPERFAMILY SSF55620 2 118 8.34E-37 T 10-11-2016 A4G23_RS15290 755a5b8b91e1d200a52fc2a546b86a2c 119 SMART SM00905 4 116 1.8E-48 T 10-11-2016 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 A4G23_RS15290 755a5b8b91e1d200a52fc2a546b86a2c 119 Gene3D G3DSA:3.30.1130.10 2 118 5.2E-46 T 10-11-2016 A4G23_RS05435 7d4274e9401c2bce2c315ace059ee56f 508 Gene3D G3DSA:2.115.10.20 10 300 6.1E-67 T 10-11-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain A4G23_RS05435 7d4274e9401c2bce2c315ace059ee56f 508 SUPERFAMILY SSF75005 11 301 1.15E-71 T 10-11-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain A4G23_RS05435 7d4274e9401c2bce2c315ace059ee56f 508 Pfam PF04616 Glycosyl hydrolases family 43 11 285 7.1E-73 T 10-11-2016 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 A4G23_RS05435 7d4274e9401c2bce2c315ace059ee56f 508 SUPERFAMILY SSF49899 315 507 4.75E-24 T 10-11-2016 IPR013320 Concanavalin A-like lectin/glucanase domain A4G23_RS05435 7d4274e9401c2bce2c315ace059ee56f 508 Gene3D G3DSA:2.60.120.200 315 507 2.5E-22 T 10-11-2016 IPR013320 Concanavalin A-like lectin/glucanase domain A4G23_RS21975 459f960f7b4d817b1cf10f4252c7eff0 360 SUPERFAMILY SSF51412 5 75 8.09E-61 T 10-11-2016 A4G23_RS21975 459f960f7b4d817b1cf10f4252c7eff0 360 SUPERFAMILY SSF51412 104 358 8.09E-61 T 10-11-2016 A4G23_RS21975 459f960f7b4d817b1cf10f4252c7eff0 360 Gene3D G3DSA:3.20.20.70 5 335 3.7E-65 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS21975 459f960f7b4d817b1cf10f4252c7eff0 360 Pfam PF03060 Nitronate monooxygenase 7 351 3.9E-81 T 10-11-2016 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 A4G23_RS13570 f9401fe87b33cd3389281d781ba03706 915 SUPERFAMILY SSF53955 163 373 2.08E-60 T 10-11-2016 IPR023346 Lysozyme-like domain A4G23_RS13570 f9401fe87b33cd3389281d781ba03706 915 Pfam PF00912 Transglycosylase 174 359 2.6E-54 T 10-11-2016 IPR001264 Glycosyl transferase, family 51 A4G23_RS13570 f9401fe87b33cd3389281d781ba03706 915 Pfam PF00905 Penicillin binding protein transpeptidase domain 465 518 6.7E-5 T 10-11-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A4G23_RS13570 f9401fe87b33cd3389281d781ba03706 915 Pfam PF00905 Penicillin binding protein transpeptidase domain 557 726 2.7E-18 T 10-11-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A4G23_RS13570 f9401fe87b33cd3389281d781ba03706 915 SUPERFAMILY SSF56601 392 791 2.09E-78 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS13570 f9401fe87b33cd3389281d781ba03706 915 SUPERFAMILY SSF56601 341 363 2.09E-78 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS13570 f9401fe87b33cd3389281d781ba03706 915 Gene3D G3DSA:3.40.710.10 360 817 2.7E-93 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS13570 f9401fe87b33cd3389281d781ba03706 915 Gene3D G3DSA:1.10.3810.10 174 359 5.1E-60 T 10-11-2016 A4G23_RS19280 840729d02fc259ffc4cd5e87635e47d5 906 Pfam PF00672 HAMP domain 356 423 2.2E-8 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS19280 840729d02fc259ffc4cd5e87635e47d5 906 Gene3D G3DSA:3.30.565.10 537 703 1.7E-14 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS19280 840729d02fc259ffc4cd5e87635e47d5 906 SUPERFAMILY SSF55874 553 700 8.51E-16 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS19280 840729d02fc259ffc4cd5e87635e47d5 906 PRINTS PR00344 Bacterial sensor protein C-terminal signature 610 624 8.4E-5 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS19280 840729d02fc259ffc4cd5e87635e47d5 906 PRINTS PR00344 Bacterial sensor protein C-terminal signature 687 700 8.4E-5 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS19280 840729d02fc259ffc4cd5e87635e47d5 906 PRINTS PR00344 Bacterial sensor protein C-terminal signature 663 681 8.4E-5 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS19280 840729d02fc259ffc4cd5e87635e47d5 906 Pfam PF08376 Nitrate and nitrite sensing 37 334 1.3E-31 T 10-11-2016 IPR013587 Nitrate/nitrite sensing protein A4G23_RS19280 840729d02fc259ffc4cd5e87635e47d5 906 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 575 701 2.9E-9 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS19280 840729d02fc259ffc4cd5e87635e47d5 906 SMART SM00304 374 428 0.0041 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS19280 840729d02fc259ffc4cd5e87635e47d5 906 SMART SM00387 572 703 8.8E-10 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS12790 e972b8e7278c32e61669f5714fed0256 116 Pfam PF06262 Zinicin-like metallopeptidase 28 115 4.3E-33 T 10-11-2016 IPR010428 Zinicin-like metallopeptidase A4G23_RS12790 e972b8e7278c32e61669f5714fed0256 116 SUPERFAMILY SSF55486 2 115 2.57E-39 T 10-11-2016 A4G23_RS08700 31002f96e4173fdbcc37dc9eb9d00b66 441 Gene3D G3DSA:3.50.50.60 2 129 4.7E-21 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS08700 31002f96e4173fdbcc37dc9eb9d00b66 441 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 307 3.1E-44 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS08700 31002f96e4173fdbcc37dc9eb9d00b66 441 SUPERFAMILY SSF51905 2 349 3.4E-38 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS08700 31002f96e4173fdbcc37dc9eb9d00b66 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 27 42 2.0E-37 T 10-11-2016 A4G23_RS08700 31002f96e4173fdbcc37dc9eb9d00b66 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 287 294 2.0E-37 T 10-11-2016 A4G23_RS08700 31002f96e4173fdbcc37dc9eb9d00b66 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 125 134 2.0E-37 T 10-11-2016 A4G23_RS08700 31002f96e4173fdbcc37dc9eb9d00b66 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 246 260 2.0E-37 T 10-11-2016 A4G23_RS08700 31002f96e4173fdbcc37dc9eb9d00b66 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 389 404 2.0E-37 T 10-11-2016 A4G23_RS08700 31002f96e4173fdbcc37dc9eb9d00b66 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 323 344 2.0E-37 T 10-11-2016 A4G23_RS08700 31002f96e4173fdbcc37dc9eb9d00b66 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 161 186 2.0E-37 T 10-11-2016 A4G23_RS08700 31002f96e4173fdbcc37dc9eb9d00b66 441 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 328 436 1.1E-23 T 10-11-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A4G23_RS08700 31002f96e4173fdbcc37dc9eb9d00b66 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 122 140 1.7E-11 T 10-11-2016 A4G23_RS08700 31002f96e4173fdbcc37dc9eb9d00b66 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 161 179 1.7E-11 T 10-11-2016 A4G23_RS08700 31002f96e4173fdbcc37dc9eb9d00b66 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 245 261 1.7E-11 T 10-11-2016 A4G23_RS08700 31002f96e4173fdbcc37dc9eb9d00b66 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 272 294 1.7E-11 T 10-11-2016 A4G23_RS08700 31002f96e4173fdbcc37dc9eb9d00b66 441 SUPERFAMILY SSF55424 323 438 4.3E-27 T 10-11-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 A4G23_RS08700 31002f96e4173fdbcc37dc9eb9d00b66 441 Gene3D G3DSA:3.30.390.30 314 439 9.8E-29 T 10-11-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A4G23_RS08700 31002f96e4173fdbcc37dc9eb9d00b66 441 Gene3D G3DSA:3.50.50.60 130 313 3.1E-39 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS08700 31002f96e4173fdbcc37dc9eb9d00b66 441 PIRSF PIRSF000350 1 440 2.2E-75 T 10-11-2016 A4G23_RS07505 6ff529c289d733f62fe0a5ce314f2039 82 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 38 80 5.0E-14 T 10-11-2016 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS07505 6ff529c289d733f62fe0a5ce314f2039 82 SUPERFAMILY SSF47336 2 81 1.01E-21 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS07505 6ff529c289d733f62fe0a5ce314f2039 82 Hamap MF_01217 Acyl carrier protein [acpP]. 7 81 16.965 T 10-11-2016 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS07505 6ff529c289d733f62fe0a5ce314f2039 82 Pfam PF00550 Phosphopantetheine attachment site 11 77 7.2E-17 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS07505 6ff529c289d733f62fe0a5ce314f2039 82 Gene3D G3DSA:1.10.1200.10 4 81 1.5E-24 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS20980 c74f77669c394ae15b74c620963e725f 1324 SUPERFAMILY SSF52540 430 650 1.43E-29 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS20980 c74f77669c394ae15b74c620963e725f 1324 SUPERFAMILY SSF52540 762 1021 6.17E-20 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS20980 c74f77669c394ae15b74c620963e725f 1324 SUPERFAMILY SSF52540 1069 1254 8.11E-11 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS20980 c74f77669c394ae15b74c620963e725f 1324 Pfam PF01580 FtsK/SpoIIIE family 806 1040 9.6E-45 T 10-11-2016 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 A4G23_RS20980 c74f77669c394ae15b74c620963e725f 1324 Pfam PF01580 FtsK/SpoIIIE family 1103 1192 2.9E-6 T 10-11-2016 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 A4G23_RS20980 c74f77669c394ae15b74c620963e725f 1324 Pfam PF01580 FtsK/SpoIIIE family 431 557 3.9E-24 T 10-11-2016 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 A4G23_RS20980 c74f77669c394ae15b74c620963e725f 1324 Gene3D G3DSA:3.40.50.300 438 651 5.9E-19 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS20980 c74f77669c394ae15b74c620963e725f 1324 Gene3D G3DSA:3.40.50.300 1235 1242 1.6E-7 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS20980 c74f77669c394ae15b74c620963e725f 1324 Gene3D G3DSA:3.40.50.300 1100 1181 1.6E-7 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS20980 c74f77669c394ae15b74c620963e725f 1324 Gene3D G3DSA:3.40.50.300 824 1008 1.3E-8 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS20980 c74f77669c394ae15b74c620963e725f 1324 TIGRFAM TIGR03925 T7SS_EccC_b: type VII secretion protein EccCb 744 1316 1.1E-235 T 10-11-2016 IPR023837 EccCb-like, Actinobacteria A4G23_RS20980 c74f77669c394ae15b74c620963e725f 1324 TIGRFAM TIGR03924 T7SS_EccC_a: type VII secretion protein EccCa 24 689 6.9E-261 T 10-11-2016 IPR023836 EccCa-like, Actinobacteria A4G23_RS20980 c74f77669c394ae15b74c620963e725f 1324 SMART SM00382 466 645 0.73 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS20980 c74f77669c394ae15b74c620963e725f 1324 SMART SM00382 825 1003 0.093 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS20980 c74f77669c394ae15b74c620963e725f 1324 SMART SM00382 1113 1284 1.4 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS02585 745f7f0ea6b97e542e354970b5bc0bae 240 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 1 203 24.306 T 10-11-2016 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 A4G23_RS02585 745f7f0ea6b97e542e354970b5bc0bae 240 PIRSF PIRSF006755 1 216 6.5E-35 T 10-11-2016 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 A4G23_RS02585 745f7f0ea6b97e542e354970b5bc0bae 240 SUPERFAMILY SSF52540 1 210 9.97E-40 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS02585 745f7f0ea6b97e542e354970b5bc0bae 240 Pfam PF13500 AAA domain 4 202 3.2E-32 T 10-11-2016 A4G23_RS02585 745f7f0ea6b97e542e354970b5bc0bae 240 Gene3D G3DSA:3.40.50.300 1 213 8.0E-56 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS02585 745f7f0ea6b97e542e354970b5bc0bae 240 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 6 170 3.5E-30 T 10-11-2016 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 A4G23_RS16260 60fbe4880c784e7996c69e1d14d71b11 162 SUPERFAMILY SSF89963 90 162 6.02E-25 T 10-11-2016 IPR007551 Protein of unknown function DUF520 A4G23_RS16260 60fbe4880c784e7996c69e1d14d71b11 162 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 3 162 25.752 T 10-11-2016 IPR007551 Protein of unknown function DUF520 A4G23_RS16260 60fbe4880c784e7996c69e1d14d71b11 162 Gene3D G3DSA:3.30.70.860 97 162 6.4E-31 T 10-11-2016 A4G23_RS16260 60fbe4880c784e7996c69e1d14d71b11 162 SUPERFAMILY SSF89963 5 87 2.62E-28 T 10-11-2016 IPR007551 Protein of unknown function DUF520 A4G23_RS16260 60fbe4880c784e7996c69e1d14d71b11 162 Gene3D G3DSA:3.30.70.990 11 96 6.6E-31 T 10-11-2016 A4G23_RS16260 60fbe4880c784e7996c69e1d14d71b11 162 Pfam PF04461 Protein of unknown function (DUF520) 4 162 9.7E-62 T 10-11-2016 IPR007551 Protein of unknown function DUF520 A4G23_RS16990 0cfcdd7182c119d496bcb6fa84580cae 568 Pfam PF01266 FAD dependent oxidoreductase 24 377 2.6E-46 T 10-11-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A4G23_RS16990 0cfcdd7182c119d496bcb6fa84580cae 568 SUPERFAMILY SSF51905 290 351 1.94E-33 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS16990 0cfcdd7182c119d496bcb6fa84580cae 568 SUPERFAMILY SSF51905 24 253 1.94E-33 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS16990 0cfcdd7182c119d496bcb6fa84580cae 568 Gene3D G3DSA:3.50.50.60 19 255 3.4E-39 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS16990 0cfcdd7182c119d496bcb6fa84580cae 568 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 376 386 - T 10-11-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 A4G23_RS16990 0cfcdd7182c119d496bcb6fa84580cae 568 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 28 45 - T 10-11-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 A4G23_RS16990 0cfcdd7182c119d496bcb6fa84580cae 568 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 404 528 3.8E-30 T 10-11-2016 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 A4G23_RS16990 0cfcdd7182c119d496bcb6fa84580cae 568 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 36 46 4.3E-31 T 10-11-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 A4G23_RS16990 0cfcdd7182c119d496bcb6fa84580cae 568 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 98 110 4.3E-31 T 10-11-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 A4G23_RS16990 0cfcdd7182c119d496bcb6fa84580cae 568 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 341 347 4.3E-31 T 10-11-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 A4G23_RS16990 0cfcdd7182c119d496bcb6fa84580cae 568 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 23 35 4.3E-31 T 10-11-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 A4G23_RS16990 0cfcdd7182c119d496bcb6fa84580cae 568 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 52 64 4.3E-31 T 10-11-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 A4G23_RS16990 0cfcdd7182c119d496bcb6fa84580cae 568 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 371 383 4.3E-31 T 10-11-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 A4G23_RS26185 7e311081273da3605ca8d72c8fc58e43 340 Gene3D G3DSA:3.40.50.720 131 302 3.1E-49 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS26185 7e311081273da3605ca8d72c8fc58e43 340 SUPERFAMILY SSF51735 114 301 2.84E-45 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS26185 7e311081273da3605ca8d72c8fc58e43 340 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 46 320 5.5E-9 T 10-11-2016 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 A4G23_RS26185 7e311081273da3605ca8d72c8fc58e43 340 Gene3D G3DSA:3.40.50.720 44 130 2.9E-14 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS26185 7e311081273da3605ca8d72c8fc58e43 340 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 124 300 1.4E-45 T 10-11-2016 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A4G23_RS26185 7e311081273da3605ca8d72c8fc58e43 340 SUPERFAMILY SSF52283 44 143 9.99E-13 T 10-11-2016 A4G23_RS05840 95431508757a09a6828198ef2bdd27cf 277 Pfam PF08241 Methyltransferase domain 74 167 1.9E-18 T 10-11-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 A4G23_RS05840 95431508757a09a6828198ef2bdd27cf 277 Gene3D G3DSA:3.40.50.150 23 255 3.5E-30 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS05840 95431508757a09a6828198ef2bdd27cf 277 SUPERFAMILY SSF53335 24 267 7.56E-34 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS06570 ed643ff4e6924258e35d56d9e7e91d6e 582 PRINTS PR01165 Cytochrome c oxidase subunit I signature 397 416 9.6E-104 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS06570 ed643ff4e6924258e35d56d9e7e91d6e 582 PRINTS PR01165 Cytochrome c oxidase subunit I signature 369 387 9.6E-104 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS06570 ed643ff4e6924258e35d56d9e7e91d6e 582 PRINTS PR01165 Cytochrome c oxidase subunit I signature 266 287 9.6E-104 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS06570 ed643ff4e6924258e35d56d9e7e91d6e 582 PRINTS PR01165 Cytochrome c oxidase subunit I signature 312 327 9.6E-104 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS06570 ed643ff4e6924258e35d56d9e7e91d6e 582 PRINTS PR01165 Cytochrome c oxidase subunit I signature 85 108 9.6E-104 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS06570 ed643ff4e6924258e35d56d9e7e91d6e 582 PRINTS PR01165 Cytochrome c oxidase subunit I signature 112 136 9.6E-104 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS06570 ed643ff4e6924258e35d56d9e7e91d6e 582 PRINTS PR01165 Cytochrome c oxidase subunit I signature 447 468 9.6E-104 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS06570 ed643ff4e6924258e35d56d9e7e91d6e 582 PRINTS PR01165 Cytochrome c oxidase subunit I signature 334 355 9.6E-104 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS06570 ed643ff4e6924258e35d56d9e7e91d6e 582 PRINTS PR01165 Cytochrome c oxidase subunit I signature 38 63 9.6E-104 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS06570 ed643ff4e6924258e35d56d9e7e91d6e 582 PRINTS PR01165 Cytochrome c oxidase subunit I signature 187 205 9.6E-104 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS06570 ed643ff4e6924258e35d56d9e7e91d6e 582 PRINTS PR01165 Cytochrome c oxidase subunit I signature 155 167 9.6E-104 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS06570 ed643ff4e6924258e35d56d9e7e91d6e 582 PRINTS PR01165 Cytochrome c oxidase subunit I signature 216 235 9.6E-104 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS06570 ed643ff4e6924258e35d56d9e7e91d6e 582 PRINTS PR01165 Cytochrome c oxidase subunit I signature 245 266 9.6E-104 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS06570 ed643ff4e6924258e35d56d9e7e91d6e 582 SUPERFAMILY SSF81442 35 546 2.75E-177 T 10-11-2016 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS06570 ed643ff4e6924258e35d56d9e7e91d6e 582 Gene3D G3DSA:1.20.210.10 31 561 7.4E-196 T 10-11-2016 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS06570 ed643ff4e6924258e35d56d9e7e91d6e 582 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 268 322 - T 10-11-2016 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS06570 ed643ff4e6924258e35d56d9e7e91d6e 582 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 48 490 2.1E-146 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS06570 ed643ff4e6924258e35d56d9e7e91d6e 582 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 39 543 4.0E-215 T 10-11-2016 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 A4G23_RS19470 2c05beb3a31c4bedeea43ed3ee61ac4e 463 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 70 327 9.0E-66 T 10-11-2016 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 A4G23_RS19470 2c05beb3a31c4bedeea43ed3ee61ac4e 463 PRINTS PR01181 Diaminopimelate decarboxylase signature 111 128 7.8E-24 T 10-11-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4G23_RS19470 2c05beb3a31c4bedeea43ed3ee61ac4e 463 PRINTS PR01181 Diaminopimelate decarboxylase signature 429 451 7.8E-24 T 10-11-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4G23_RS19470 2c05beb3a31c4bedeea43ed3ee61ac4e 463 PRINTS PR01181 Diaminopimelate decarboxylase signature 346 364 7.8E-24 T 10-11-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4G23_RS19470 2c05beb3a31c4bedeea43ed3ee61ac4e 463 PRINTS PR01181 Diaminopimelate decarboxylase signature 200 209 7.8E-24 T 10-11-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4G23_RS19470 2c05beb3a31c4bedeea43ed3ee61ac4e 463 SUPERFAMILY SSF51419 63 328 8.0E-78 T 10-11-2016 IPR029066 PLP-binding barrel A4G23_RS19470 2c05beb3a31c4bedeea43ed3ee61ac4e 463 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 93 111 - T 10-11-2016 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site A4G23_RS19470 2c05beb3a31c4bedeea43ed3ee61ac4e 463 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 267 280 - T 10-11-2016 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site A4G23_RS19470 2c05beb3a31c4bedeea43ed3ee61ac4e 463 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 44 461 2.4E-146 T 10-11-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4G23_RS19470 2c05beb3a31c4bedeea43ed3ee61ac4e 463 Gene3D G3DSA:3.20.20.10 72 314 3.7E-93 T 10-11-2016 IPR029066 PLP-binding barrel A4G23_RS19470 2c05beb3a31c4bedeea43ed3ee61ac4e 463 SUPERFAMILY SSF50621 302 462 1.67E-49 T 10-11-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A4G23_RS19470 2c05beb3a31c4bedeea43ed3ee61ac4e 463 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 335 438 6.3E-16 T 10-11-2016 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 A4G23_RS19470 2c05beb3a31c4bedeea43ed3ee61ac4e 463 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 419 432 1.6E-16 T 10-11-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A4G23_RS19470 2c05beb3a31c4bedeea43ed3ee61ac4e 463 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 317 336 1.6E-16 T 10-11-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A4G23_RS19470 2c05beb3a31c4bedeea43ed3ee61ac4e 463 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 93 111 1.6E-16 T 10-11-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A4G23_RS19470 2c05beb3a31c4bedeea43ed3ee61ac4e 463 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 228 241 1.6E-16 T 10-11-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A4G23_RS19470 2c05beb3a31c4bedeea43ed3ee61ac4e 463 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 113 125 1.6E-16 T 10-11-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A4G23_RS19470 2c05beb3a31c4bedeea43ed3ee61ac4e 463 Gene3D G3DSA:2.40.37.10 315 462 4.9E-49 T 10-11-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A4G23_RS19470 2c05beb3a31c4bedeea43ed3ee61ac4e 463 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 52 462 39.672 T 10-11-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4G23_RS06965 208868bd38fb384c58bf67eeff05686f 246 Gene3D G3DSA:3.40.50.720 24 225 4.6E-58 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS06965 208868bd38fb384c58bf67eeff05686f 246 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 24 115 2.2E-23 T 10-11-2016 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal A4G23_RS06965 208868bd38fb384c58bf67eeff05686f 246 TIGRFAM TIGR01915 npdG: NADPH-dependent F420 reductase 22 228 1.3E-75 T 10-11-2016 IPR010185 NADPH-dependent F420 reductase GO:0006740|GO:0016651|GO:0050661|GO:0055114|GO:0070967 A4G23_RS06965 208868bd38fb384c58bf67eeff05686f 246 SUPERFAMILY SSF51735 24 226 1.62E-38 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS16690 8dfe30d009aada8f033be1eec2cead11 201 Gene3D G3DSA:3.30.230.10 101 181 9.9E-32 T 10-11-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A4G23_RS16690 8dfe30d009aada8f033be1eec2cead11 201 ProSitePatterns PS00585 Ribosomal protein S5 signature. 51 83 - T 10-11-2016 IPR018192 Ribosomal protein S5, N-terminal, conserved site A4G23_RS16690 8dfe30d009aada8f033be1eec2cead11 201 Gene3D G3DSA:3.30.160.20 34 95 2.1E-28 T 10-11-2016 IPR014720 Double-stranded RNA-binding domain A4G23_RS16690 8dfe30d009aada8f033be1eec2cead11 201 SUPERFAMILY SSF54211 102 181 3.79E-24 T 10-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold A4G23_RS16690 8dfe30d009aada8f033be1eec2cead11 201 Pfam PF00333 Ribosomal protein S5, N-terminal domain 36 98 5.2E-27 T 10-11-2016 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 A4G23_RS16690 8dfe30d009aada8f033be1eec2cead11 201 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 32 186 7.6E-68 T 10-11-2016 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 A4G23_RS16690 8dfe30d009aada8f033be1eec2cead11 201 SUPERFAMILY SSF54768 33 99 1.46E-21 T 10-11-2016 A4G23_RS16690 8dfe30d009aada8f033be1eec2cead11 201 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 186 34.376 T 10-11-2016 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 A4G23_RS16690 8dfe30d009aada8f033be1eec2cead11 201 Pfam PF03719 Ribosomal protein S5, C-terminal domain 110 180 5.6E-28 T 10-11-2016 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 A4G23_RS21075 04918f5f830a84901a42bd3180111a68 952 SMART SM00382 608 806 3.1E-4 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS21075 04918f5f830a84901a42bd3180111a68 952 SUPERFAMILY SSF46785 874 939 2.72E-17 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS21075 04918f5f830a84901a42bd3180111a68 952 SMART SM00843 873 937 9.7E-30 T 10-11-2016 IPR018541 FtsK gamma domain A4G23_RS21075 04918f5f830a84901a42bd3180111a68 952 Pfam PF01580 FtsK/SpoIIIE family 575 773 5.9E-55 T 10-11-2016 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 A4G23_RS21075 04918f5f830a84901a42bd3180111a68 952 Gene3D G3DSA:3.40.50.300 547 840 1.9E-82 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS21075 04918f5f830a84901a42bd3180111a68 952 SUPERFAMILY SSF52540 546 845 1.21E-46 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS21075 04918f5f830a84901a42bd3180111a68 952 Pfam PF09397 Ftsk gamma domain 877 934 6.8E-22 T 10-11-2016 IPR018541 FtsK gamma domain A4G23_RS20410 c58903a446b43dcae85506159c474075 211 Pfam PF02620 Uncharacterized ACR, COG1399 67 186 3.8E-35 T 10-11-2016 IPR003772 Protein of unknown function DUF177 A4G23_RS14845 22ef2b45b4cb7dae0cad01c188f2d4cc 296 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 225 241 - T 10-11-2016 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 A4G23_RS14845 22ef2b45b4cb7dae0cad01c188f2d4cc 296 SMART SM00525 224 244 2.4E-6 T 10-11-2016 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 A4G23_RS14845 22ef2b45b4cb7dae0cad01c188f2d4cc 296 SMART SM00478 76 223 2.1E-59 T 10-11-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A4G23_RS14845 22ef2b45b4cb7dae0cad01c188f2d4cc 296 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 225 241 2.2E-4 T 10-11-2016 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 A4G23_RS14845 22ef2b45b4cb7dae0cad01c188f2d4cc 296 ProSitePatterns PS01155 Endonuclease III family signature. 140 169 - T 10-11-2016 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 A4G23_RS14845 22ef2b45b4cb7dae0cad01c188f2d4cc 296 TIGRFAM TIGR01083 nth: endonuclease III 43 232 1.1E-75 T 10-11-2016 IPR005759 Endonuclease III GO:0003906|GO:0006284 A4G23_RS14845 22ef2b45b4cb7dae0cad01c188f2d4cc 296 Gene3D G3DSA:1.10.340.30 61 160 1.6E-36 T 10-11-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A4G23_RS14845 22ef2b45b4cb7dae0cad01c188f2d4cc 296 Hamap MF_00942 Endonuclease III [nth]. 34 247 38.25 T 10-11-2016 IPR005759 Endonuclease III GO:0003906|GO:0006284 A4G23_RS14845 22ef2b45b4cb7dae0cad01c188f2d4cc 296 SUPERFAMILY SSF48150 43 251 5.02E-70 T 10-11-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A4G23_RS14845 22ef2b45b4cb7dae0cad01c188f2d4cc 296 Gene3D G3DSA:1.10.1670.10 161 246 2.2E-33 T 10-11-2016 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 A4G23_RS14845 22ef2b45b4cb7dae0cad01c188f2d4cc 296 Pfam PF00633 Helix-hairpin-helix motif 137 164 1.1E-7 T 10-11-2016 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 A4G23_RS14845 22ef2b45b4cb7dae0cad01c188f2d4cc 296 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 72 201 9.0E-22 T 10-11-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A4G23_RS00215 a92e5cf949b810fb255c34f42a2ae9bb 302 Pfam PF00248 Aldo/keto reductase family 13 289 3.6E-51 T 10-11-2016 IPR023210 NADP-dependent oxidoreductase domain A4G23_RS00215 a92e5cf949b810fb255c34f42a2ae9bb 302 SUPERFAMILY SSF51430 7 292 4.85E-66 T 10-11-2016 IPR023210 NADP-dependent oxidoreductase domain A4G23_RS00215 a92e5cf949b810fb255c34f42a2ae9bb 302 Gene3D G3DSA:3.20.20.100 11 292 3.8E-64 T 10-11-2016 IPR023210 NADP-dependent oxidoreductase domain A4G23_RS13480 1ca52d6591a2985afc6d8c3664bc22e4 108 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 16 68 2.0E-24 T 10-11-2016 IPR002696 Putative membrane protein insertion efficiency factor A4G23_RS13480 1ca52d6591a2985afc6d8c3664bc22e4 108 SMART SM01234 1 68 1.1E-43 T 10-11-2016 IPR002696 Putative membrane protein insertion efficiency factor A4G23_RS13480 1ca52d6591a2985afc6d8c3664bc22e4 108 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 1 69 24.35 T 10-11-2016 IPR002696 Putative membrane protein insertion efficiency factor A4G23_RS13480 1ca52d6591a2985afc6d8c3664bc22e4 108 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 5 73 2.8E-27 T 10-11-2016 IPR002696 Putative membrane protein insertion efficiency factor A4G23_RS13480 1ca52d6591a2985afc6d8c3664bc22e4 108 Pfam PF01809 Haemolytic domain 5 68 2.0E-28 T 10-11-2016 IPR002696 Putative membrane protein insertion efficiency factor A4G23_RS00485 d51399049bb002d4feaaf873441fb27f 86 PIRSF PIRSF028743 1 85 1.2E-35 T 10-11-2016 IPR008634 Gas vesicle protein GvpO GO:0031412 A4G23_RS00485 d51399049bb002d4feaaf873441fb27f 86 Pfam PF05800 Gas vesicle synthesis protein GvpO 3 83 6.5E-35 T 10-11-2016 IPR008634 Gas vesicle protein GvpO GO:0031412 A4G23_RS09300 2a3c77442d86c759c6d6acc85ddba29f 259 Pfam PF13344 Haloacid dehalogenase-like hydrolase 10 109 7.8E-25 T 10-11-2016 IPR006357 HAD-superfamily hydrolase, subfamily IIA A4G23_RS09300 2a3c77442d86c759c6d6acc85ddba29f 259 PIRSF PIRSF000915 3 259 5.9E-52 T 10-11-2016 IPR006357 HAD-superfamily hydrolase, subfamily IIA A4G23_RS09300 2a3c77442d86c759c6d6acc85ddba29f 259 Gene3D G3DSA:3.40.50.10410 88 181 6.9E-33 T 10-11-2016 IPR023215 Nitrophenylphosphatase-like domain A4G23_RS09300 2a3c77442d86c759c6d6acc85ddba29f 259 Gene3D G3DSA:3.40.50.1000 6 83 6.9E-39 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS09300 2a3c77442d86c759c6d6acc85ddba29f 259 Gene3D G3DSA:3.40.50.1000 182 257 6.9E-39 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS09300 2a3c77442d86c759c6d6acc85ddba29f 259 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 11 231 7.3E-46 T 10-11-2016 IPR006357 HAD-superfamily hydrolase, subfamily IIA A4G23_RS09300 2a3c77442d86c759c6d6acc85ddba29f 259 Pfam PF13242 HAD-hyrolase-like 182 255 1.0E-20 T 10-11-2016 A4G23_RS09300 2a3c77442d86c759c6d6acc85ddba29f 259 SUPERFAMILY SSF56784 7 257 6.3E-68 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS09730 02e2436dcff2c57a8b89f048449df2c4 229 SUPERFAMILY SSF52540 1 220 6.69E-70 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS09730 02e2436dcff2c57a8b89f048449df2c4 229 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 215 2.2E-85 T 10-11-2016 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 A4G23_RS09730 02e2436dcff2c57a8b89f048449df2c4 229 Gene3D G3DSA:3.40.50.300 1 219 1.2E-72 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS09730 02e2436dcff2c57a8b89f048449df2c4 229 Pfam PF00005 ABC transporter 19 166 4.0E-34 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS09730 02e2436dcff2c57a8b89f048449df2c4 229 SMART SM00382 28 215 2.6E-15 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS09730 02e2436dcff2c57a8b89f048449df2c4 229 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS04315 d2e3cb38c348187e2cbe8a2c1c84775a 588 SUPERFAMILY SSF52540 475 515 1.51E-50 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS04315 d2e3cb38c348187e2cbe8a2c1c84775a 588 SUPERFAMILY SSF52540 227 431 1.51E-50 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS04315 d2e3cb38c348187e2cbe8a2c1c84775a 588 SMART SM00382 265 419 4.0E-22 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS04315 d2e3cb38c348187e2cbe8a2c1c84775a 588 ProSitePatterns PS00674 AAA-protein family signature. 387 405 - T 10-11-2016 IPR003960 ATPase, AAA-type, conserved site GO:0005524 A4G23_RS04315 d2e3cb38c348187e2cbe8a2c1c84775a 588 Pfam PF16450 Proteasomal ATPase OB/ID domain 97 226 2.6E-53 T 10-11-2016 IPR032501 Proteasomal ATPase, OB/ID domain A4G23_RS04315 d2e3cb38c348187e2cbe8a2c1c84775a 588 Hamap MF_02112 Proteasome-associated ATPase [mpa]. 54 566 50.553 T 10-11-2016 IPR022482 Proteasome ATPase GO:0000502|GO:0010498|GO:0016887|GO:0019941 A4G23_RS04315 d2e3cb38c348187e2cbe8a2c1c84775a 588 Gene3D G3DSA:3.40.50.300 217 433 4.9E-59 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS04315 d2e3cb38c348187e2cbe8a2c1c84775a 588 TIGRFAM TIGR03689 pup_AAA: proteasome ATPase 52 565 2.3E-253 T 10-11-2016 IPR022482 Proteasome ATPase GO:0000502|GO:0010498|GO:0016887|GO:0019941 A4G23_RS04315 d2e3cb38c348187e2cbe8a2c1c84775a 588 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 269 417 2.8E-47 T 10-11-2016 IPR003959 ATPase, AAA-type, core GO:0005524 A4G23_RS22850 94326649b075f3be4c9674d0e231fab7 905 Gene3D G3DSA:3.40.1060.10 241 358 3.4E-36 T 10-11-2016 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 A4G23_RS22850 94326649b075f3be4c9674d0e231fab7 905 SUPERFAMILY SSF52016 642 902 3.14E-86 T 10-11-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel A4G23_RS22850 94326649b075f3be4c9674d0e231fab7 905 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 26 903 0.0 T 10-11-2016 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3 A4G23_RS22850 94326649b075f3be4c9674d0e231fab7 905 SUPERFAMILY SSF53732 4 638 2.88E-221 T 10-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4G23_RS22850 94326649b075f3be4c9674d0e231fab7 905 PRINTS PR00415 Aconitase family signature 270 283 3.4E-42 T 10-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4G23_RS22850 94326649b075f3be4c9674d0e231fab7 905 PRINTS PR00415 Aconitase family signature 284 297 3.4E-42 T 10-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4G23_RS22850 94326649b075f3be4c9674d0e231fab7 905 PRINTS PR00415 Aconitase family signature 363 377 3.4E-42 T 10-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4G23_RS22850 94326649b075f3be4c9674d0e231fab7 905 PRINTS PR00415 Aconitase family signature 141 154 3.4E-42 T 10-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4G23_RS22850 94326649b075f3be4c9674d0e231fab7 905 PRINTS PR00415 Aconitase family signature 165 173 3.4E-42 T 10-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4G23_RS22850 94326649b075f3be4c9674d0e231fab7 905 PRINTS PR00415 Aconitase family signature 194 207 3.4E-42 T 10-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4G23_RS22850 94326649b075f3be4c9674d0e231fab7 905 PRINTS PR00415 Aconitase family signature 208 223 3.4E-42 T 10-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4G23_RS22850 94326649b075f3be4c9674d0e231fab7 905 PRINTS PR00415 Aconitase family signature 504 517 3.4E-42 T 10-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4G23_RS22850 94326649b075f3be4c9674d0e231fab7 905 PRINTS PR00415 Aconitase family signature 442 453 3.4E-42 T 10-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4G23_RS22850 94326649b075f3be4c9674d0e231fab7 905 ProSitePatterns PS01244 Aconitase family signature 2. 504 517 - T 10-11-2016 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 A4G23_RS22850 94326649b075f3be4c9674d0e231fab7 905 Gene3D G3DSA:3.30.499.10 359 384 2.7E-64 T 10-11-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 A4G23_RS22850 94326649b075f3be4c9674d0e231fab7 905 Gene3D G3DSA:3.30.499.10 430 586 2.7E-64 T 10-11-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 A4G23_RS22850 94326649b075f3be4c9674d0e231fab7 905 Gene3D G3DSA:3.30.499.10 28 240 3.8E-78 T 10-11-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 A4G23_RS22850 94326649b075f3be4c9674d0e231fab7 905 Gene3D G3DSA:3.20.19.10 648 902 1.2E-77 T 10-11-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel A4G23_RS22850 94326649b075f3be4c9674d0e231fab7 905 ProSitePatterns PS00450 Aconitase family signature 1. 438 454 - T 10-11-2016 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 A4G23_RS22850 94326649b075f3be4c9674d0e231fab7 905 Pfam PF00330 Aconitase family (aconitate hydratase) 64 573 2.2E-182 T 10-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4G23_RS22850 94326649b075f3be4c9674d0e231fab7 905 Pfam PF00694 Aconitase C-terminal domain 703 832 5.5E-44 T 10-11-2016 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 A4G23_RS15790 2eb287b0c2851de852957da3be0ef479 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 10-11-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4G23_RS15790 2eb287b0c2851de852957da3be0ef479 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 9.6E-5 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS15790 2eb287b0c2851de852957da3be0ef479 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 9.6E-5 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS15790 2eb287b0c2851de852957da3be0ef479 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 9.6E-5 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS15790 2eb287b0c2851de852957da3be0ef479 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 1.3E-22 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS15790 2eb287b0c2851de852957da3be0ef479 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.3E-22 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS15790 2eb287b0c2851de852957da3be0ef479 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.3E-22 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS15790 2eb287b0c2851de852957da3be0ef479 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.3E-22 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS15790 2eb287b0c2851de852957da3be0ef479 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.3E-22 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS15790 2eb287b0c2851de852957da3be0ef479 255 Gene3D G3DSA:3.40.50.720 8 240 4.5E-63 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS15790 2eb287b0c2851de852957da3be0ef479 255 Pfam PF00106 short chain dehydrogenase 9 192 4.9E-50 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS15790 2eb287b0c2851de852957da3be0ef479 255 SUPERFAMILY SSF51735 9 243 5.69E-62 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS15790 2eb287b0c2851de852957da3be0ef479 255 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 185 0.0017 T 10-11-2016 A4G23_RS16345 af8b27e9e2016c25041c02d36f1e683a 144 ProSitePatterns PS00359 Ribosomal protein L11 signature. 129 144 - T 10-11-2016 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS16345 af8b27e9e2016c25041c02d36f1e683a 144 Gene3D G3DSA:1.10.10.250 75 143 5.6E-32 T 10-11-2016 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 A4G23_RS16345 af8b27e9e2016c25041c02d36f1e683a 144 SUPERFAMILY SSF46906 70 143 6.02E-27 T 10-11-2016 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 A4G23_RS16345 af8b27e9e2016c25041c02d36f1e683a 144 SMART SM00649 12 143 6.9E-86 T 10-11-2016 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 A4G23_RS16345 af8b27e9e2016c25041c02d36f1e683a 144 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 39 76 6.0E-17 T 10-11-2016 A4G23_RS16345 af8b27e9e2016c25041c02d36f1e683a 144 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 6 143 2.2E-63 T 10-11-2016 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS16345 af8b27e9e2016c25041c02d36f1e683a 144 SUPERFAMILY SSF54747 5 75 6.8E-30 T 10-11-2016 IPR020784 Ribosomal protein L11, N-terminal A4G23_RS16345 af8b27e9e2016c25041c02d36f1e683a 144 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 8 144 31.186 T 10-11-2016 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 A4G23_RS16345 af8b27e9e2016c25041c02d36f1e683a 144 Gene3D G3DSA:3.30.1550.10 5 74 2.8E-38 T 10-11-2016 IPR020784 Ribosomal protein L11, N-terminal A4G23_RS16345 af8b27e9e2016c25041c02d36f1e683a 144 Pfam PF00298 Ribosomal protein L11, RNA binding domain 74 142 8.4E-25 T 10-11-2016 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 A4G23_RS16345 af8b27e9e2016c25041c02d36f1e683a 144 Pfam PF03946 Ribosomal protein L11, N-terminal domain 12 69 6.1E-29 T 10-11-2016 IPR020784 Ribosomal protein L11, N-terminal A4G23_RS24805 47dc372e1c61cf5d9ca328160a2383b2 545 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS24805 47dc372e1c61cf5d9ca328160a2383b2 545 SUPERFAMILY SSF52540 357 543 2.96E-33 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS24805 47dc372e1c61cf5d9ca328160a2383b2 545 Gene3D G3DSA:3.40.50.300 364 543 9.5E-29 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS24805 47dc372e1c61cf5d9ca328160a2383b2 545 Gene3D G3DSA:3.40.50.300 7 277 4.6E-43 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS24805 47dc372e1c61cf5d9ca328160a2383b2 545 SUPERFAMILY SSF52540 5 229 5.43E-41 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS24805 47dc372e1c61cf5d9ca328160a2383b2 545 Pfam PF00005 ABC transporter 22 187 1.8E-22 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS24805 47dc372e1c61cf5d9ca328160a2383b2 545 Pfam PF00005 ABC transporter 368 495 2.6E-14 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS24805 47dc372e1c61cf5d9ca328160a2383b2 545 SMART SM00382 374 541 3.4E-10 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS24805 47dc372e1c61cf5d9ca328160a2383b2 545 SMART SM00382 29 232 4.5E-10 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS03965 78df8211ed66d981fd4b0a5248ba05fb 515 Gene3D G3DSA:1.20.1250.20 14 204 8.1E-30 T 10-11-2016 A4G23_RS03965 78df8211ed66d981fd4b0a5248ba05fb 515 PRINTS PR01036 Tetracycline resistance protein TetB signature 408 427 1.8E-5 T 10-11-2016 A4G23_RS03965 78df8211ed66d981fd4b0a5248ba05fb 515 PRINTS PR01036 Tetracycline resistance protein TetB signature 147 171 1.8E-5 T 10-11-2016 A4G23_RS03965 78df8211ed66d981fd4b0a5248ba05fb 515 PRINTS PR01036 Tetracycline resistance protein TetB signature 368 388 1.8E-5 T 10-11-2016 A4G23_RS03965 78df8211ed66d981fd4b0a5248ba05fb 515 SUPERFAMILY SSF103473 8 206 8.5E-68 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS03965 78df8211ed66d981fd4b0a5248ba05fb 515 SUPERFAMILY SSF103473 478 505 8.5E-68 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS03965 78df8211ed66d981fd4b0a5248ba05fb 515 SUPERFAMILY SSF103473 256 427 8.5E-68 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS03965 78df8211ed66d981fd4b0a5248ba05fb 515 Pfam PF07690 Major Facilitator Superfamily 26 417 1.2E-50 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS03965 78df8211ed66d981fd4b0a5248ba05fb 515 Gene3D G3DSA:1.20.1250.20 479 505 3.8E-17 T 10-11-2016 A4G23_RS03965 78df8211ed66d981fd4b0a5248ba05fb 515 Gene3D G3DSA:1.20.1250.20 273 428 3.8E-17 T 10-11-2016 A4G23_RS00125 bd0be5c4dd87f8d7c1cda028de824f88 342 Gene3D G3DSA:3.40.47.10 187 340 2.7E-25 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS00125 bd0be5c4dd87f8d7c1cda028de824f88 342 Gene3D G3DSA:3.40.47.10 12 186 1.2E-39 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS00125 bd0be5c4dd87f8d7c1cda028de824f88 342 SUPERFAMILY SSF53901 11 340 2.38E-38 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS00125 bd0be5c4dd87f8d7c1cda028de824f88 342 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 256 340 3.9E-14 T 10-11-2016 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A4G23_RS00125 bd0be5c4dd87f8d7c1cda028de824f88 342 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 122 205 4.0E-14 T 10-11-2016 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A4G23_RS27315 bd0be5c4dd87f8d7c1cda028de824f88 342 Gene3D G3DSA:3.40.47.10 187 340 2.7E-25 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS27315 bd0be5c4dd87f8d7c1cda028de824f88 342 Gene3D G3DSA:3.40.47.10 12 186 1.2E-39 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS27315 bd0be5c4dd87f8d7c1cda028de824f88 342 SUPERFAMILY SSF53901 11 340 2.38E-38 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS27315 bd0be5c4dd87f8d7c1cda028de824f88 342 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 256 340 3.9E-14 T 10-11-2016 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A4G23_RS27315 bd0be5c4dd87f8d7c1cda028de824f88 342 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 122 205 4.0E-14 T 10-11-2016 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A4G23_RS04285 72b1a03e96fe314c7d0bedccd754d792 342 SMART SM00354 11 83 1.7E-19 T 10-11-2016 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4G23_RS04285 72b1a03e96fe314c7d0bedccd754d792 342 SUPERFAMILY SSF47413 11 71 4.64E-14 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS04285 72b1a03e96fe314c7d0bedccd754d792 342 Pfam PF00356 Bacterial regulatory proteins, lacI family 15 60 6.7E-13 T 10-11-2016 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4G23_RS04285 72b1a03e96fe314c7d0bedccd754d792 342 Pfam PF13377 Periplasmic binding protein-like domain 178 336 1.6E-34 T 10-11-2016 A4G23_RS04285 72b1a03e96fe314c7d0bedccd754d792 342 SUPERFAMILY SSF53822 70 322 6.71E-49 T 10-11-2016 IPR028082 Periplasmic binding protein-like I A4G23_RS04285 72b1a03e96fe314c7d0bedccd754d792 342 Gene3D G3DSA:1.10.260.40 12 64 5.0E-21 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS04285 72b1a03e96fe314c7d0bedccd754d792 342 Gene3D G3DSA:3.40.50.2300 65 179 1.6E-23 T 10-11-2016 A4G23_RS04285 72b1a03e96fe314c7d0bedccd754d792 342 Gene3D G3DSA:3.40.50.2300 180 338 2.5E-41 T 10-11-2016 A4G23_RS21100 f3014bff6043de5002bd07c821d714ca 127 Pfam PF13560 Helix-turn-helix domain 8 65 3.6E-11 T 10-11-2016 A4G23_RS21100 f3014bff6043de5002bd07c821d714ca 127 Gene3D G3DSA:1.10.260.40 8 74 1.9E-15 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS21100 f3014bff6043de5002bd07c821d714ca 127 SMART SM00530 11 66 1.4E-9 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS21100 f3014bff6043de5002bd07c821d714ca 127 SUPERFAMILY SSF47413 3 73 1.27E-13 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS12510 e0f3c4836a335b1d86d8dfc2e8803827 769 Gene3D G3DSA:3.30.870.10 581 763 1.2E-69 T 10-11-2016 A4G23_RS12510 e0f3c4836a335b1d86d8dfc2e8803827 769 SUPERFAMILY SSF143724 192 388 9.02E-65 T 10-11-2016 A4G23_RS12510 e0f3c4836a335b1d86d8dfc2e8803827 769 Pfam PF13089 Polyphosphate kinase N-terminal domain 89 195 3.6E-36 T 10-11-2016 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 A4G23_RS12510 e0f3c4836a335b1d86d8dfc2e8803827 769 PIRSF PIRSF015589 76 769 3.2E-281 T 10-11-2016 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 A4G23_RS12510 e0f3c4836a335b1d86d8dfc2e8803827 769 Pfam PF13090 Polyphosphate kinase C-terminal domain 410 756 3.0E-152 T 10-11-2016 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 A4G23_RS12510 e0f3c4836a335b1d86d8dfc2e8803827 769 SUPERFAMILY SSF56024 581 762 6.73E-64 T 10-11-2016 A4G23_RS12510 e0f3c4836a335b1d86d8dfc2e8803827 769 Hamap MF_00347 Polyphosphate kinase [ppk]. 86 762 33.936 T 10-11-2016 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 A4G23_RS12510 e0f3c4836a335b1d86d8dfc2e8803827 769 SUPERFAMILY SSF56024 405 578 6.28E-56 T 10-11-2016 A4G23_RS12510 e0f3c4836a335b1d86d8dfc2e8803827 769 SUPERFAMILY SSF140356 86 190 4.05E-35 T 10-11-2016 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 A4G23_RS12510 e0f3c4836a335b1d86d8dfc2e8803827 769 Pfam PF02503 Polyphosphate kinase middle domain 204 394 1.3E-65 T 10-11-2016 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 A4G23_RS12510 e0f3c4836a335b1d86d8dfc2e8803827 769 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 88 758 5.9E-249 T 10-11-2016 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 A4G23_RS12510 e0f3c4836a335b1d86d8dfc2e8803827 769 Gene3D G3DSA:3.30.870.10 404 580 1.6E-78 T 10-11-2016 A4G23_RS12510 e0f3c4836a335b1d86d8dfc2e8803827 769 Gene3D G3DSA:3.30.1840.10 191 376 1.6E-72 T 10-11-2016 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 A4G23_RS19055 182991f254e53e281e946133d612a116 318 Gene3D G3DSA:1.10.601.10 87 165 1.7E-27 T 10-11-2016 A4G23_RS19055 182991f254e53e281e946133d612a116 318 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 92 314 2.4E-95 T 10-11-2016 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS19055 182991f254e53e281e946133d612a116 318 Pfam PF04539 Sigma-70 region 3 181 237 2.4E-15 T 10-11-2016 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS19055 182991f254e53e281e946133d612a116 318 Pfam PF04545 Sigma-70, region 4 263 312 1.9E-16 T 10-11-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS19055 182991f254e53e281e946133d612a116 318 SUPERFAMILY SSF88946 74 167 3.66E-32 T 10-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS19055 182991f254e53e281e946133d612a116 318 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 94 314 1.3E-38 T 10-11-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS19055 182991f254e53e281e946133d612a116 318 PRINTS PR00046 Major sigma-70 factor signature 146 154 1.1E-9 T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS19055 182991f254e53e281e946133d612a116 318 PRINTS PR00046 Major sigma-70 factor signature 267 279 1.1E-9 T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS19055 182991f254e53e281e946133d612a116 318 PRINTS PR00046 Major sigma-70 factor signature 284 299 1.1E-9 T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS19055 182991f254e53e281e946133d612a116 318 PRINTS PR00046 Major sigma-70 factor signature 122 135 1.1E-9 T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS19055 182991f254e53e281e946133d612a116 318 PRINTS PR00046 Major sigma-70 factor signature 299 310 1.1E-9 T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS19055 182991f254e53e281e946133d612a116 318 Gene3D G3DSA:1.10.10.10 166 221 6.0E-23 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS19055 182991f254e53e281e946133d612a116 318 SUPERFAMILY SSF88659 171 245 1.48E-15 T 10-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS19055 182991f254e53e281e946133d612a116 318 Gene3D G3DSA:1.10.10.10 255 314 7.2E-11 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS19055 182991f254e53e281e946133d612a116 318 Pfam PF04542 Sigma-70 region 2 98 167 2.0E-21 T 10-11-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS19055 182991f254e53e281e946133d612a116 318 SUPERFAMILY SSF88659 234 314 6.92E-17 T 10-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS19510 ca7c30a89c80e95ce66106f3bda80b77 358 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 2 356 1.2E-149 T 10-11-2016 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 A4G23_RS19510 ca7c30a89c80e95ce66106f3bda80b77 358 Pfam PF03462 PCRF domain 11 206 4.9E-67 T 10-11-2016 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 A4G23_RS19510 ca7c30a89c80e95ce66106f3bda80b77 358 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 230 246 - T 10-11-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 A4G23_RS19510 ca7c30a89c80e95ce66106f3bda80b77 358 SUPERFAMILY SSF75620 8 355 1.57E-127 T 10-11-2016 A4G23_RS19510 ca7c30a89c80e95ce66106f3bda80b77 358 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 1 358 37.614 T 10-11-2016 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 A4G23_RS19510 ca7c30a89c80e95ce66106f3bda80b77 358 Pfam PF00472 RF-1 domain 214 323 2.5E-40 T 10-11-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 A4G23_RS19510 ca7c30a89c80e95ce66106f3bda80b77 358 SMART SM00937 63 181 4.9E-54 T 10-11-2016 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 A4G23_RS19510 ca7c30a89c80e95ce66106f3bda80b77 358 Gene3D G3DSA:3.30.160.20 213 291 6.2E-34 T 10-11-2016 IPR014720 Double-stranded RNA-binding domain A4G23_RS19510 ca7c30a89c80e95ce66106f3bda80b77 358 Gene3D G3DSA:1.20.58.410 5 78 2.6E-16 T 10-11-2016 A4G23_RS00660 f43ac0cb3dd5e285468244e776be96bf 955 Gene3D G3DSA:3.20.20.300 6 320 8.8E-85 T 10-11-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4G23_RS00660 f43ac0cb3dd5e285468244e776be96bf 955 SUPERFAMILY SSF50405 461 542 4.58E-11 T 10-11-2016 IPR008999 Actin cross-linking A4G23_RS00660 f43ac0cb3dd5e285468244e776be96bf 955 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 53 308 3.9E-39 T 10-11-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4G23_RS00660 f43ac0cb3dd5e285468244e776be96bf 955 Gene3D G3DSA:3.40.50.1700 562 709 5.4E-60 T 10-11-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 A4G23_RS00660 f43ac0cb3dd5e285468244e776be96bf 955 Gene3D G3DSA:3.40.50.1700 332 412 5.4E-60 T 10-11-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 A4G23_RS00660 f43ac0cb3dd5e285468244e776be96bf 955 Pfam PF14310 Fibronectin type III-like domain 739 809 2.5E-19 T 10-11-2016 IPR026891 Fibronectin type III-like domain A4G23_RS00660 f43ac0cb3dd5e285468244e776be96bf 955 SUPERFAMILY SSF49785 831 951 2.72E-6 T 10-11-2016 IPR008979 Galactose-binding domain-like A4G23_RS00660 f43ac0cb3dd5e285468244e776be96bf 955 SMART SM01217 739 809 4.9E-27 T 10-11-2016 IPR026891 Fibronectin type III-like domain A4G23_RS00660 f43ac0cb3dd5e285468244e776be96bf 955 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 348 706 2.4E-58 T 10-11-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 A4G23_RS00660 f43ac0cb3dd5e285468244e776be96bf 955 SUPERFAMILY SSF51445 6 346 7.9E-80 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS00660 f43ac0cb3dd5e285468244e776be96bf 955 Gene3D G3DSA:2.80.10.50 460 547 2.8E-14 T 10-11-2016 A4G23_RS00660 f43ac0cb3dd5e285468244e776be96bf 955 Gene3D G3DSA:2.60.120.260 835 951 6.1E-7 T 10-11-2016 IPR008979 Galactose-binding domain-like A4G23_RS00660 f43ac0cb3dd5e285468244e776be96bf 955 SUPERFAMILY SSF52279 348 413 5.1E-44 T 10-11-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 A4G23_RS00660 f43ac0cb3dd5e285468244e776be96bf 955 SUPERFAMILY SSF52279 562 709 5.1E-44 T 10-11-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 A4G23_RS00660 f43ac0cb3dd5e285468244e776be96bf 955 PRINTS PR00133 Glycosyl hydrolase family 3 signature 69 88 7.4E-7 T 10-11-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4G23_RS00660 f43ac0cb3dd5e285468244e776be96bf 955 PRINTS PR00133 Glycosyl hydrolase family 3 signature 157 173 7.4E-7 T 10-11-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4G23_RS00660 f43ac0cb3dd5e285468244e776be96bf 955 SMART SM00606 828 952 0.0048 T 10-11-2016 IPR006584 Cellulose binding, type IV GO:0030246 A4G23_RS04495 918703faccf6ff007e18f04f7cc3b730 232 Gene3D G3DSA:1.10.10.10 4 72 3.8E-18 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS04495 918703faccf6ff007e18f04f7cc3b730 232 SUPERFAMILY SSF46785 5 74 1.43E-15 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS04495 918703faccf6ff007e18f04f7cc3b730 232 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 70 1.6E-10 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS04495 918703faccf6ff007e18f04f7cc3b730 232 SMART SM00895 99 223 8.7E-15 T 10-11-2016 IPR011711 GntR, C-terminal A4G23_RS04495 918703faccf6ff007e18f04f7cc3b730 232 SUPERFAMILY SSF48008 96 226 1.33E-18 T 10-11-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal A4G23_RS04495 918703faccf6ff007e18f04f7cc3b730 232 Gene3D G3DSA:1.20.120.530 86 220 1.7E-17 T 10-11-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal A4G23_RS04495 918703faccf6ff007e18f04f7cc3b730 232 SMART SM00345 12 70 3.4E-8 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS04495 918703faccf6ff007e18f04f7cc3b730 232 Pfam PF07729 FCD domain 100 219 3.1E-17 T 10-11-2016 IPR011711 GntR, C-terminal A4G23_RS06540 d73f9cd89d8860e269811805d9a1bee0 349 SUPERFAMILY SSF50022 167 348 4.71E-26 T 10-11-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A4G23_RS06540 d73f9cd89d8860e269811805d9a1bee0 349 Gene3D G3DSA:2.102.10.10 162 348 3.6E-35 T 10-11-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A4G23_RS06540 d73f9cd89d8860e269811805d9a1bee0 349 Pfam PF00355 Rieske [2Fe-2S] domain 233 320 2.0E-10 T 10-11-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A4G23_RS11665 dd7d5b705af56762e77830fee3371d05 331 SMART SM00421 264 321 1.2E-12 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS11665 dd7d5b705af56762e77830fee3371d05 331 SUPERFAMILY SSF46894 254 328 1.29E-14 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS11665 dd7d5b705af56762e77830fee3371d05 331 Pfam PF00196 Bacterial regulatory proteins, luxR family 267 317 3.8E-9 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS11665 dd7d5b705af56762e77830fee3371d05 331 Gene3D G3DSA:1.10.10.10 261 327 4.2E-15 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS11010 b0cd60d54ba515dc60eaf69a9f2752bd 242 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 72 1.6E-18 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS11010 b0cd60d54ba515dc60eaf69a9f2752bd 242 SUPERFAMILY SSF64288 60 240 8.79E-32 T 10-11-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain A4G23_RS11010 b0cd60d54ba515dc60eaf69a9f2752bd 242 SMART SM00345 13 72 7.0E-19 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS11010 b0cd60d54ba515dc60eaf69a9f2752bd 242 SMART SM00866 92 234 7.3E-17 T 10-11-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A4G23_RS11010 b0cd60d54ba515dc60eaf69a9f2752bd 242 SUPERFAMILY SSF46785 7 76 5.46E-21 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS11010 b0cd60d54ba515dc60eaf69a9f2752bd 242 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 32 46 1.0E-6 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS11010 b0cd60d54ba515dc60eaf69a9f2752bd 242 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 62 1.0E-6 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS11010 b0cd60d54ba515dc60eaf69a9f2752bd 242 Gene3D G3DSA:3.40.1410.10 73 236 6.2E-41 T 10-11-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain A4G23_RS11010 b0cd60d54ba515dc60eaf69a9f2752bd 242 Gene3D G3DSA:1.10.10.10 7 72 5.9E-24 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS11010 b0cd60d54ba515dc60eaf69a9f2752bd 242 Pfam PF07702 UTRA domain 99 232 1.8E-25 T 10-11-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A4G23_RS07100 945ed09b9ad4aac1a94c25c058129250 480 SMART SM00955 53 371 5.0E-50 T 10-11-2016 A4G23_RS07100 945ed09b9ad4aac1a94c25c058129250 480 SUPERFAMILY SSF50249 21 414 1.09E-84 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS07100 945ed09b9ad4aac1a94c25c058129250 480 Pfam PF00773 RNB domain 55 360 2.6E-40 T 10-11-2016 A4G23_RS08460 9c5ad801b0d5f96f2bf9645f2ef7cd70 1047 SUPERFAMILY SSF55545 85 229 6.67E-16 T 10-11-2016 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A4G23_RS08460 9c5ad801b0d5f96f2bf9645f2ef7cd70 1047 SUPERFAMILY SSF51445 232 539 9.9E-84 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS08460 9c5ad801b0d5f96f2bf9645f2ef7cd70 1047 SUPERFAMILY SSF140657 555 684 4.19E-18 T 10-11-2016 A4G23_RS08460 9c5ad801b0d5f96f2bf9645f2ef7cd70 1047 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 86 228 1.2E-23 T 10-11-2016 IPR015882 Beta-hexosaminidase, bacteial type, N-terminal KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 A4G23_RS08460 9c5ad801b0d5f96f2bf9645f2ef7cd70 1047 Pfam PF00754 F5/8 type C domain 917 1029 4.8E-21 T 10-11-2016 IPR000421 Coagulation factor 5/8 C-terminal domain A4G23_RS08460 9c5ad801b0d5f96f2bf9645f2ef7cd70 1047 Pfam PF07555 beta-N-acetylglucosaminidase 234 541 2.1E-97 T 10-11-2016 IPR011496 Beta-N-acetylglucosaminidase MetaCyc: PWY-7437 A4G23_RS08460 9c5ad801b0d5f96f2bf9645f2ef7cd70 1047 Gene3D G3DSA:3.30.379.10 83 228 3.2E-17 T 10-11-2016 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A4G23_RS08460 9c5ad801b0d5f96f2bf9645f2ef7cd70 1047 SUPERFAMILY SSF49785 913 1035 6.95E-22 T 10-11-2016 IPR008979 Galactose-binding domain-like A4G23_RS08460 9c5ad801b0d5f96f2bf9645f2ef7cd70 1047 Gene3D G3DSA:2.60.120.260 916 1037 9.3E-24 T 10-11-2016 IPR008979 Galactose-binding domain-like A4G23_RS04305 1d619da0d7bdf1292e0625613d6695b9 72 Pfam PF05639 Pup-like protein 4 72 1.1E-31 T 10-11-2016 IPR008515 Ubiquitin-like, Pup A4G23_RS04305 1d619da0d7bdf1292e0625613d6695b9 72 TIGRFAM TIGR03687 pupylate_cterm: ubiquitin-like protein Pup 41 72 4.6E-21 T 10-11-2016 IPR008515 Ubiquitin-like, Pup A4G23_RS04305 1d619da0d7bdf1292e0625613d6695b9 72 Hamap MF_02106 Prokaryotic ubiquitin-like protein Pup [pup]. 1 72 17.735 T 10-11-2016 IPR008515 Ubiquitin-like, Pup A4G23_RS02255 296a1a72d2412b8fa14b1f794013f1bf 197 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 137 151 2.6E-5 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS02255 296a1a72d2412b8fa14b1f794013f1bf 197 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 167 2.6E-5 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS02255 296a1a72d2412b8fa14b1f794013f1bf 197 Pfam PF00196 Bacterial regulatory proteins, luxR family 136 190 2.0E-11 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS02255 296a1a72d2412b8fa14b1f794013f1bf 197 SMART SM00421 134 191 5.9E-13 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS02255 296a1a72d2412b8fa14b1f794013f1bf 197 SUPERFAMILY SSF46894 125 197 1.77E-17 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS02255 296a1a72d2412b8fa14b1f794013f1bf 197 Gene3D G3DSA:1.10.10.10 114 196 4.3E-20 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS20245 715341cd2b6cc10be625d3ebc994e413 1149 SMART SM00387 600 712 2.0E-8 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS20245 715341cd2b6cc10be625d3ebc994e413 1149 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 603 710 9.3E-9 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS20245 715341cd2b6cc10be625d3ebc994e413 1149 Pfam PF08376 Nitrate and nitrite sensing 109 378 8.7E-40 T 10-11-2016 IPR013587 Nitrate/nitrite sensing protein A4G23_RS20245 715341cd2b6cc10be625d3ebc994e413 1149 SUPERFAMILY SSF55874 592 709 6.55E-15 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS20245 715341cd2b6cc10be625d3ebc994e413 1149 Gene3D G3DSA:3.30.565.10 567 709 7.1E-12 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS20245 715341cd2b6cc10be625d3ebc994e413 1149 SMART SM00304 418 488 7.0E-4 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS20245 715341cd2b6cc10be625d3ebc994e413 1149 Pfam PF00672 HAMP domain 400 484 2.4E-14 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS04055 c4579f7216ae7dfda2052fb756c157d2 166 SUPERFAMILY SSF160904 6 159 2.09E-27 T 10-11-2016 A4G23_RS04055 c4579f7216ae7dfda2052fb756c157d2 166 Pfam PF07336 Putative stress-induced transcription regulator 5 100 6.8E-7 T 10-11-2016 IPR010852 Putative stress-induced transcription regulator A4G23_RS04055 c4579f7216ae7dfda2052fb756c157d2 166 Gene3D G3DSA:1.10.3300.10 5 161 6.8E-34 T 10-11-2016 IPR023286 ABATE domain A4G23_RS04055 c4579f7216ae7dfda2052fb756c157d2 166 Pfam PF11706 CGNR zinc finger 122 159 3.9E-9 T 10-11-2016 IPR021005 Zinc finger, CGNR A4G23_RS19485 43cea2c6f87d743f3b8fb365e4c3a99f 305 Pfam PF00288 GHMP kinases N terminal domain 88 151 1.9E-12 T 10-11-2016 IPR006204 GHMP kinase N-terminal domain GO:0005524 A4G23_RS19485 43cea2c6f87d743f3b8fb365e4c3a99f 305 SUPERFAMILY SSF55060 173 286 7.2E-27 T 10-11-2016 IPR013750 GHMP kinase, C-terminal domain A4G23_RS19485 43cea2c6f87d743f3b8fb365e4c3a99f 305 Hamap MF_00384 Homoserine kinase [thrB]. 11 300 29.545 T 10-11-2016 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 A4G23_RS19485 43cea2c6f87d743f3b8fb365e4c3a99f 305 SUPERFAMILY SSF54211 11 157 1.21E-30 T 10-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold A4G23_RS19485 43cea2c6f87d743f3b8fb365e4c3a99f 305 TIGRFAM TIGR00191 thrB: homoserine kinase 11 279 2.2E-64 T 10-11-2016 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 A4G23_RS19485 43cea2c6f87d743f3b8fb365e4c3a99f 305 Gene3D G3DSA:3.30.230.10 10 160 7.7E-59 T 10-11-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A4G23_RS19485 43cea2c6f87d743f3b8fb365e4c3a99f 305 PRINTS PR00958 Homoserine kinase signature 18 33 8.1E-33 T 10-11-2016 A4G23_RS19485 43cea2c6f87d743f3b8fb365e4c3a99f 305 PRINTS PR00958 Homoserine kinase signature 177 194 8.1E-33 T 10-11-2016 A4G23_RS19485 43cea2c6f87d743f3b8fb365e4c3a99f 305 PRINTS PR00958 Homoserine kinase signature 138 151 8.1E-33 T 10-11-2016 A4G23_RS19485 43cea2c6f87d743f3b8fb365e4c3a99f 305 PRINTS PR00958 Homoserine kinase signature 101 116 8.1E-33 T 10-11-2016 A4G23_RS19485 43cea2c6f87d743f3b8fb365e4c3a99f 305 PRINTS PR00958 Homoserine kinase signature 254 269 8.1E-33 T 10-11-2016 A4G23_RS19485 43cea2c6f87d743f3b8fb365e4c3a99f 305 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 94 105 - T 10-11-2016 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 A4G23_RS19485 43cea2c6f87d743f3b8fb365e4c3a99f 305 Pfam PF08544 GHMP kinases C terminal 222 279 3.8E-6 T 10-11-2016 IPR013750 GHMP kinase, C-terminal domain A4G23_RS19485 43cea2c6f87d743f3b8fb365e4c3a99f 305 Gene3D G3DSA:3.30.70.890 173 292 1.9E-33 T 10-11-2016 IPR013750 GHMP kinase, C-terminal domain A4G23_RS19485 43cea2c6f87d743f3b8fb365e4c3a99f 305 PIRSF PIRSF000676 7 300 2.6E-84 T 10-11-2016 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 A4G23_RS08970 875d950b216a6fe4b9cbeda5546c7315 652 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 117 326 2.1E-78 T 10-11-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A4G23_RS08970 875d950b216a6fe4b9cbeda5546c7315 652 SUPERFAMILY SSF51230 569 643 5.37E-21 T 10-11-2016 IPR011053 Single hybrid motif A4G23_RS08970 875d950b216a6fe4b9cbeda5546c7315 652 SUPERFAMILY SSF51246 335 450 1.67E-37 T 10-11-2016 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4G23_RS08970 875d950b216a6fe4b9cbeda5546c7315 652 Gene3D G3DSA:3.30.1490.20 132 203 1.0E-25 T 10-11-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A4G23_RS08970 875d950b216a6fe4b9cbeda5546c7315 652 Pfam PF02785 Biotin carboxylase C-terminal domain 340 446 1.1E-35 T 10-11-2016 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4G23_RS08970 875d950b216a6fe4b9cbeda5546c7315 652 Gene3D G3DSA:3.30.470.20 205 449 1.2E-97 T 10-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 A4G23_RS08970 875d950b216a6fe4b9cbeda5546c7315 652 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 599 616 - T 10-11-2016 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4G23_RS08970 875d950b216a6fe4b9cbeda5546c7315 652 Pfam PF00364 Biotin-requiring enzyme 577 641 3.3E-17 T 10-11-2016 IPR000089 Biotin/lipoyl attachment A4G23_RS08970 875d950b216a6fe4b9cbeda5546c7315 652 Pfam PF00289 Biotin carboxylase, N-terminal domain 3 112 3.8E-43 T 10-11-2016 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4G23_RS08970 875d950b216a6fe4b9cbeda5546c7315 652 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 290 297 - T 10-11-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A4G23_RS08970 875d950b216a6fe4b9cbeda5546c7315 652 Gene3D G3DSA:2.40.50.100 574 643 2.3E-23 T 10-11-2016 A4G23_RS08970 875d950b216a6fe4b9cbeda5546c7315 652 SUPERFAMILY SSF56059 85 352 4.07E-69 T 10-11-2016 A4G23_RS08970 875d950b216a6fe4b9cbeda5546c7315 652 SUPERFAMILY SSF52440 2 115 3.74E-47 T 10-11-2016 IPR016185 Pre-ATP-grasp domain A4G23_RS08970 875d950b216a6fe4b9cbeda5546c7315 652 Gene3D G3DSA:3.40.50.20 3 131 1.0E-49 T 10-11-2016 IPR016185 Pre-ATP-grasp domain A4G23_RS08970 875d950b216a6fe4b9cbeda5546c7315 652 SMART SM00878 340 446 4.3E-54 T 10-11-2016 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4G23_RS25365 9d3be6c76013bde7bad25c7ed1cf950a 1810 SUPERFAMILY SSF48452 1140 1303 7.21E-6 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS25365 9d3be6c76013bde7bad25c7ed1cf950a 1810 Gene3D G3DSA:1.25.40.10 1141 1190 6.8E-7 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS25365 9d3be6c76013bde7bad25c7ed1cf950a 1810 Gene3D G3DSA:1.25.40.10 1231 1300 6.8E-7 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS25365 9d3be6c76013bde7bad25c7ed1cf950a 1810 SUPERFAMILY SSF52980 1521 1801 6.43E-121 T 10-11-2016 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A4G23_RS25365 9d3be6c76013bde7bad25c7ed1cf950a 1810 SUPERFAMILY SSF52540 673 846 5.31E-12 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS25365 9d3be6c76013bde7bad25c7ed1cf950a 1810 Gene3D G3DSA:1.10.10.10 1675 1800 4.3E-41 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS25365 9d3be6c76013bde7bad25c7ed1cf950a 1810 Gene3D G3DSA:3.40.600.10 1513 1674 2.9E-52 T 10-11-2016 IPR011337 DNA mismatch repair MutH/Restriction endonuclease, type II GO:0003677|GO:0004519 A4G23_RS25365 9d3be6c76013bde7bad25c7ed1cf950a 1810 Pfam PF09126 Restriction endonuclease NaeI 1530 1798 5.2E-71 T 10-11-2016 IPR015210 Type-2 restriction enzyme NaeI GO:0009036|GO:0009307 A4G23_RS24735 9cab98173020269b44e8009bfa5db1b6 399 Gene3D G3DSA:3.30.1540.10 217 286 3.6E-12 T 10-11-2016 A4G23_RS24735 9cab98173020269b44e8009bfa5db1b6 399 Gene3D G3DSA:3.40.50.10540 1 201 1.8E-89 T 10-11-2016 IPR023606 CoA-transferase family III domain A4G23_RS24735 9cab98173020269b44e8009bfa5db1b6 399 Gene3D G3DSA:3.40.50.10540 287 356 1.8E-89 T 10-11-2016 IPR023606 CoA-transferase family III domain A4G23_RS24735 9cab98173020269b44e8009bfa5db1b6 399 Pfam PF02515 CoA-transferase family III 1 347 9.3E-83 T 10-11-2016 IPR003673 CoA-transferase family III GO:0003824 A4G23_RS24735 9cab98173020269b44e8009bfa5db1b6 399 SUPERFAMILY SSF89796 1 357 1.1E-107 T 10-11-2016 IPR023606 CoA-transferase family III domain A4G23_RS16505 ef84f6f0343ae67a42e49fb390589ef3 708 SMART SM00838 614 701 3.2E-58 T 10-11-2016 IPR000640 Translation elongation factor EFG, V domain A4G23_RS16505 ef84f6f0343ae67a42e49fb390589ef3 708 SUPERFAMILY SSF54980 617 704 6.71E-30 T 10-11-2016 IPR009022 Elongation factor G, III-V domain A4G23_RS16505 ef84f6f0343ae67a42e49fb390589ef3 708 SUPERFAMILY SSF50447 276 416 5.42E-37 T 10-11-2016 IPR009000 Translation protein, beta-barrel domain A4G23_RS16505 ef84f6f0343ae67a42e49fb390589ef3 708 Pfam PF00009 Elongation factor Tu GTP binding domain 10 293 2.2E-65 T 10-11-2016 A4G23_RS16505 ef84f6f0343ae67a42e49fb390589ef3 708 Pfam PF00679 Elongation factor G C-terminus 614 700 6.4E-30 T 10-11-2016 IPR000640 Translation elongation factor EFG, V domain A4G23_RS16505 ef84f6f0343ae67a42e49fb390589ef3 708 Pfam PF03764 Elongation factor G, domain IV 491 612 7.4E-48 T 10-11-2016 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 A4G23_RS16505 ef84f6f0343ae67a42e49fb390589ef3 708 Gene3D G3DSA:3.30.70.870 417 492 3.1E-38 T 10-11-2016 A4G23_RS16505 ef84f6f0343ae67a42e49fb390589ef3 708 SUPERFAMILY SSF52540 7 293 3.99E-105 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS16505 ef84f6f0343ae67a42e49fb390589ef3 708 Gene3D G3DSA:3.40.50.300 7 298 6.8E-105 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS16505 ef84f6f0343ae67a42e49fb390589ef3 708 TIGRFAM TIGR00484 EF-G: translation elongation factor G 5 706 0.0 T 10-11-2016 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A4G23_RS16505 ef84f6f0343ae67a42e49fb390589ef3 708 Gene3D G3DSA:3.30.230.10 496 610 1.2E-47 T 10-11-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A4G23_RS16505 ef84f6f0343ae67a42e49fb390589ef3 708 PRINTS PR00315 GTP-binding elongation factor signature 135 144 4.2E-16 T 10-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4G23_RS16505 ef84f6f0343ae67a42e49fb390589ef3 708 PRINTS PR00315 GTP-binding elongation factor signature 13 26 4.2E-16 T 10-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4G23_RS16505 ef84f6f0343ae67a42e49fb390589ef3 708 PRINTS PR00315 GTP-binding elongation factor signature 99 110 4.2E-16 T 10-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4G23_RS16505 ef84f6f0343ae67a42e49fb390589ef3 708 PRINTS PR00315 GTP-binding elongation factor signature 83 93 4.2E-16 T 10-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4G23_RS16505 ef84f6f0343ae67a42e49fb390589ef3 708 PRINTS PR00315 GTP-binding elongation factor signature 59 67 4.2E-16 T 10-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4G23_RS16505 ef84f6f0343ae67a42e49fb390589ef3 708 SMART SM00889 492 612 1.4E-70 T 10-11-2016 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 A4G23_RS16505 ef84f6f0343ae67a42e49fb390589ef3 708 Hamap MF_00054_B Elongation factor G [fusA]. 7 705 110.639 T 10-11-2016 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A4G23_RS16505 ef84f6f0343ae67a42e49fb390589ef3 708 Gene3D G3DSA:2.40.30.10 317 416 6.0E-39 T 10-11-2016 A4G23_RS16505 ef84f6f0343ae67a42e49fb390589ef3 708 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 11 185 1.7E-33 T 10-11-2016 IPR005225 Small GTP-binding protein domain GO:0005525 A4G23_RS16505 ef84f6f0343ae67a42e49fb390589ef3 708 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 52 67 - T 10-11-2016 IPR031157 Tr-type G domain, conserved site A4G23_RS16505 ef84f6f0343ae67a42e49fb390589ef3 708 SUPERFAMILY SSF54211 491 613 6.83E-41 T 10-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold A4G23_RS16505 ef84f6f0343ae67a42e49fb390589ef3 708 Pfam PF03144 Elongation factor Tu domain 2 336 403 2.2E-15 T 10-11-2016 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A4G23_RS16505 ef84f6f0343ae67a42e49fb390589ef3 708 SUPERFAMILY SSF54980 416 493 2.27E-25 T 10-11-2016 IPR009022 Elongation factor G, III-V domain A4G23_RS16505 ef84f6f0343ae67a42e49fb390589ef3 708 Gene3D G3DSA:3.30.70.240 611 705 2.5E-34 T 10-11-2016 IPR000640 Translation elongation factor EFG, V domain A4G23_RS16505 ef84f6f0343ae67a42e49fb390589ef3 708 Pfam PF14492 Elongation Factor G, domain II 416 490 4.6E-34 T 10-11-2016 IPR009022 Elongation factor G, III-V domain A4G23_RS19915 93d6e9d86ab88184aa9b9786af84ec61 200 Gene3D G3DSA:3.40.50.2300 1 142 8.6E-34 T 10-11-2016 A4G23_RS19915 93d6e9d86ab88184aa9b9786af84ec61 200 SMART SM00448 2 116 1.1E-26 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS19915 93d6e9d86ab88184aa9b9786af84ec61 200 ProSitePatterns PS00622 LuxR-type HTH domain signature. 154 181 - T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS19915 93d6e9d86ab88184aa9b9786af84ec61 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 182 8.7E-9 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS19915 93d6e9d86ab88184aa9b9786af84ec61 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 140 154 8.7E-9 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS19915 93d6e9d86ab88184aa9b9786af84ec61 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 170 8.7E-9 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS19915 93d6e9d86ab88184aa9b9786af84ec61 200 Pfam PF00196 Bacterial regulatory proteins, luxR family 139 193 7.3E-12 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS19915 93d6e9d86ab88184aa9b9786af84ec61 200 SMART SM00421 137 194 1.2E-15 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS19915 93d6e9d86ab88184aa9b9786af84ec61 200 SUPERFAMILY SSF52172 1 130 4.27E-29 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS19915 93d6e9d86ab88184aa9b9786af84ec61 200 Gene3D G3DSA:1.10.10.10 143 200 2.5E-18 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS19915 93d6e9d86ab88184aa9b9786af84ec61 200 Pfam PF00072 Response regulator receiver domain 4 116 1.8E-21 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS19915 93d6e9d86ab88184aa9b9786af84ec61 200 SUPERFAMILY SSF46894 130 200 1.02E-16 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS24115 e025135f8990f1076ab8e5fb5fc9e8f3 337 Pfam PF00296 Luciferase-like monooxygenase 6 311 2.7E-54 T 10-11-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4G23_RS24115 e025135f8990f1076ab8e5fb5fc9e8f3 337 Gene3D G3DSA:3.20.20.30 1 336 2.3E-70 T 10-11-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4G23_RS24115 e025135f8990f1076ab8e5fb5fc9e8f3 337 TIGRFAM TIGR03842 F420_CPS_4043: F420-dependent oxidoreductase, CPS_4043 family 2 335 2.1E-178 T 10-11-2016 IPR022315 F420-dependent oxidoreductase-predicted, CPS4043 A4G23_RS24115 e025135f8990f1076ab8e5fb5fc9e8f3 337 SUPERFAMILY SSF51679 1 334 3.79E-58 T 10-11-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4G23_RS23895 e29351a26fae94b8da8a58935133d19c 363 Pfam PF02687 FtsX-like permease family 247 355 3.1E-11 T 10-11-2016 IPR003838 ABC transporter permease protein domain GO:0016020 A4G23_RS01880 31cb198657e3d5463d3677a80abfefd7 152 Gene3D G3DSA:3.90.190.10 66 151 1.8E-16 T 10-11-2016 IPR029021 Protein-tyrosine phosphatase-like A4G23_RS01880 31cb198657e3d5463d3677a80abfefd7 152 SUPERFAMILY SSF52799 52 150 2.45E-16 T 10-11-2016 IPR029021 Protein-tyrosine phosphatase-like A4G23_RS24005 cc617aeeb4f3211d739e3705ad3768db 440 SUPERFAMILY SSF52777 4 167 9.78E-19 T 10-11-2016 A4G23_RS24005 cc617aeeb4f3211d739e3705ad3768db 440 Pfam PF00668 Condensation domain 27 156 5.8E-5 T 10-11-2016 IPR001242 Condensation domain A4G23_RS24005 cc617aeeb4f3211d739e3705ad3768db 440 SUPERFAMILY SSF52777 199 436 2.22E-30 T 10-11-2016 A4G23_RS24005 cc617aeeb4f3211d739e3705ad3768db 440 Gene3D G3DSA:3.30.559.10 129 166 4.4E-4 T 10-11-2016 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 A4G23_RS24005 cc617aeeb4f3211d739e3705ad3768db 440 Gene3D G3DSA:3.30.559.10 226 322 8.3E-5 T 10-11-2016 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 A4G23_RS20995 1f83aba273e6c696c7bb91e7631241d9 742 TIGRFAM TIGR02696 pppGpp_PNP: guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase 5 722 0.0 T 10-11-2016 IPR014069 Guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase GO:0004654|GO:0005737|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 A4G23_RS20995 1f83aba273e6c696c7bb91e7631241d9 742 SMART SM00322 579 644 4.7E-12 T 10-11-2016 IPR004087 K Homology domain GO:0003676 A4G23_RS20995 1f83aba273e6c696c7bb91e7631241d9 742 Gene3D G3DSA:2.40.50.140 653 720 6.0E-17 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS20995 1f83aba273e6c696c7bb91e7631241d9 742 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 17 720 1.7E-261 T 10-11-2016 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 A4G23_RS20995 1f83aba273e6c696c7bb91e7631241d9 742 Pfam PF00575 S1 RNA binding domain 648 718 3.5E-12 T 10-11-2016 IPR003029 S1 domain GO:0003676 A4G23_RS20995 1f83aba273e6c696c7bb91e7631241d9 742 SMART SM00316 649 723 2.5E-17 T 10-11-2016 IPR022967 RNA-binding domain, S1 A4G23_RS20995 1f83aba273e6c696c7bb91e7631241d9 742 Pfam PF00013 KH domain 583 637 2.7E-10 T 10-11-2016 IPR004088 K Homology domain, type 1 GO:0003723 A4G23_RS20995 1f83aba273e6c696c7bb91e7631241d9 742 SUPERFAMILY SSF54791 576 688 4.51E-19 T 10-11-2016 IPR004088 K Homology domain, type 1 GO:0003723 A4G23_RS20995 1f83aba273e6c696c7bb91e7631241d9 742 Gene3D G3DSA:3.30.230.70 336 570 6.0E-81 T 10-11-2016 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A4G23_RS20995 1f83aba273e6c696c7bb91e7631241d9 742 Gene3D G3DSA:3.30.230.70 8 249 9.5E-85 T 10-11-2016 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A4G23_RS20995 1f83aba273e6c696c7bb91e7631241d9 742 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 9 726 26.987 T 10-11-2016 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 A4G23_RS20995 1f83aba273e6c696c7bb91e7631241d9 742 Gene3D G3DSA:3.30.1370.10 579 652 5.0E-23 T 10-11-2016 IPR004088 K Homology domain, type 1 GO:0003723 A4G23_RS20995 1f83aba273e6c696c7bb91e7631241d9 742 SUPERFAMILY SSF55666 152 260 4.1E-29 T 10-11-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A4G23_RS20995 1f83aba273e6c696c7bb91e7631241d9 742 SUPERFAMILY SSF55666 474 573 1.78E-24 T 10-11-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A4G23_RS20995 1f83aba273e6c696c7bb91e7631241d9 742 SUPERFAMILY SSF46915 264 345 1.1E-17 T 10-11-2016 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 A4G23_RS20995 1f83aba273e6c696c7bb91e7631241d9 742 PIRSF PIRSF005499 7 742 4.5E-285 T 10-11-2016 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 A4G23_RS20995 1f83aba273e6c696c7bb91e7631241d9 742 SUPERFAMILY SSF54211 321 492 7.59E-42 T 10-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold A4G23_RS20995 1f83aba273e6c696c7bb91e7631241d9 742 Pfam PF01138 3' exoribonuclease family, domain 1 20 151 4.9E-18 T 10-11-2016 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A4G23_RS20995 1f83aba273e6c696c7bb91e7631241d9 742 Pfam PF01138 3' exoribonuclease family, domain 1 348 480 9.1E-14 T 10-11-2016 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A4G23_RS20995 1f83aba273e6c696c7bb91e7631241d9 742 SUPERFAMILY SSF54211 6 151 7.59E-46 T 10-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold A4G23_RS20995 1f83aba273e6c696c7bb91e7631241d9 742 Gene3D G3DSA:1.10.10.400 263 335 1.3E-24 T 10-11-2016 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 A4G23_RS20995 1f83aba273e6c696c7bb91e7631241d9 742 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 267 343 6.5E-18 T 10-11-2016 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 A4G23_RS11260 0ac9cb643d2782780f264f13d37a8157 406 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 284 299 1.9E-20 T 10-11-2016 A4G23_RS11260 0ac9cb643d2782780f264f13d37a8157 406 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 157 172 1.9E-20 T 10-11-2016 A4G23_RS11260 0ac9cb643d2782780f264f13d37a8157 406 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 299 315 1.9E-20 T 10-11-2016 A4G23_RS11260 0ac9cb643d2782780f264f13d37a8157 406 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 1.9E-20 T 10-11-2016 A4G23_RS11260 0ac9cb643d2782780f264f13d37a8157 406 Gene3D G3DSA:3.50.50.60 272 356 2.7E-43 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS11260 0ac9cb643d2782780f264f13d37a8157 406 Gene3D G3DSA:3.50.50.60 5 183 2.7E-43 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS11260 0ac9cb643d2782780f264f13d37a8157 406 Pfam PF01494 FAD binding domain 6 342 1.2E-50 T 10-11-2016 IPR002938 FAD-binding domain GO:0071949 A4G23_RS11260 0ac9cb643d2782780f264f13d37a8157 406 SUPERFAMILY SSF51905 7 178 1.3E-56 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS11260 0ac9cb643d2782780f264f13d37a8157 406 SUPERFAMILY SSF51905 271 361 1.3E-56 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS00825 81b2dc08a175d89360bd872fec46dd73 487 Pfam PF05195 Aminopeptidase P, N-terminal domain 50 168 1.6E-17 T 10-11-2016 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 A4G23_RS00825 81b2dc08a175d89360bd872fec46dd73 487 SUPERFAMILY SSF53092 44 218 4.03E-24 T 10-11-2016 IPR028980 Creatinase/Aminopeptidase P, N-terminal A4G23_RS00825 81b2dc08a175d89360bd872fec46dd73 487 Gene3D G3DSA:3.40.350.10 44 222 2.2E-35 T 10-11-2016 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A4G23_RS00825 81b2dc08a175d89360bd872fec46dd73 487 SMART SM01011 42 192 5.4E-34 T 10-11-2016 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 A4G23_RS00825 81b2dc08a175d89360bd872fec46dd73 487 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 395 407 - T 10-11-2016 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site A4G23_RS00825 81b2dc08a175d89360bd872fec46dd73 487 SUPERFAMILY SSF55920 219 482 4.84E-65 T 10-11-2016 IPR000994 Peptidase M24, structural domain A4G23_RS00825 81b2dc08a175d89360bd872fec46dd73 487 Pfam PF00557 Metallopeptidase family M24 226 461 7.8E-48 T 10-11-2016 IPR000994 Peptidase M24, structural domain A4G23_RS00825 81b2dc08a175d89360bd872fec46dd73 487 Gene3D G3DSA:3.90.230.10 223 479 1.5E-63 T 10-11-2016 IPR000994 Peptidase M24, structural domain A4G23_RS15005 e95b3a7246a869ebfe8efc75b7c3e6ed 288 Gene3D G3DSA:1.10.1040.10 218 287 1.5E-4 T 10-11-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A4G23_RS15005 e95b3a7246a869ebfe8efc75b7c3e6ed 288 PIRSF PIRSF000103 1 288 2.2E-34 T 10-11-2016 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 A4G23_RS15005 e95b3a7246a869ebfe8efc75b7c3e6ed 288 SUPERFAMILY SSF51735 10 162 2.27E-29 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS15005 e95b3a7246a869ebfe8efc75b7c3e6ed 288 Gene3D G3DSA:3.40.50.720 8 163 6.3E-31 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS15005 e95b3a7246a869ebfe8efc75b7c3e6ed 288 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 10 157 6.5E-24 T 10-11-2016 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 A4G23_RS15005 e95b3a7246a869ebfe8efc75b7c3e6ed 288 SUPERFAMILY SSF48179 177 287 4.87E-5 T 10-11-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A4G23_RS12025 ebe25e42cb727ccc272134e861251581 80 Pfam PF11662 Protein of unknown function (DUF3263) 9 80 1.7E-32 T 10-11-2016 IPR021678 Protein of unknown function DUF3263 A4G23_RS13505 bdcb73f8a79a6c712d91157d37c174a6 364 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 81 259 2.0E-59 T 10-11-2016 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 A4G23_RS13505 bdcb73f8a79a6c712d91157d37c174a6 364 Pfam PF02195 ParB-like nuclease domain 84 173 1.7E-26 T 10-11-2016 IPR003115 ParB/Sulfiredoxin A4G23_RS13505 bdcb73f8a79a6c712d91157d37c174a6 364 Gene3D G3DSA:3.90.1530.10 79 180 3.0E-39 T 10-11-2016 A4G23_RS13505 bdcb73f8a79a6c712d91157d37c174a6 364 SMART SM00470 83 174 7.1E-37 T 10-11-2016 IPR003115 ParB/Sulfiredoxin A4G23_RS13505 bdcb73f8a79a6c712d91157d37c174a6 364 SUPERFAMILY SSF109709 166 276 7.72E-32 T 10-11-2016 A4G23_RS13505 bdcb73f8a79a6c712d91157d37c174a6 364 SUPERFAMILY SSF110849 84 176 1.74E-28 T 10-11-2016 IPR003115 ParB/Sulfiredoxin A4G23_RS21190 bf41557da215ef7a181123c3ed6d2363 293 Gene3D G3DSA:1.10.3720.10 64 270 1.2E-36 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS21190 bf41557da215ef7a181123c3ed6d2363 293 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 62 161 3.8E-15 T 10-11-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 A4G23_RS21190 bf41557da215ef7a181123c3ed6d2363 293 SUPERFAMILY SSF161098 63 253 3.53E-35 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS21190 bf41557da215ef7a181123c3ed6d2363 293 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 83 268 1.0E-16 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS19870 97da8aa2e502672c98fb0ac9e8730505 611 SUPERFAMILY SSF52540 354 594 8.83E-74 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS19870 97da8aa2e502672c98fb0ac9e8730505 611 ProSitePatterns PS00211 ABC transporters family signature. 499 513 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS19870 97da8aa2e502672c98fb0ac9e8730505 611 Gene3D G3DSA:3.40.50.300 358 590 3.0E-72 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS19870 97da8aa2e502672c98fb0ac9e8730505 611 Gene3D G3DSA:1.20.1560.10 24 334 9.1E-69 T 10-11-2016 A4G23_RS19870 97da8aa2e502672c98fb0ac9e8730505 611 Pfam PF00005 ABC transporter 378 526 1.5E-30 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS19870 97da8aa2e502672c98fb0ac9e8730505 611 SUPERFAMILY SSF90123 24 336 7.72E-72 T 10-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A4G23_RS19870 97da8aa2e502672c98fb0ac9e8730505 611 Pfam PF00664 ABC transporter transmembrane region 39 307 4.5E-40 T 10-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A4G23_RS19870 97da8aa2e502672c98fb0ac9e8730505 611 SMART SM00382 387 580 2.1E-14 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS01340 0c58af651ed5bc96150e9df196dc480b 628 SUPERFAMILY SSF52518 402 614 8.29E-45 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS01340 0c58af651ed5bc96150e9df196dc480b 628 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 423 581 1.8E-38 T 10-11-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A4G23_RS01340 0c58af651ed5bc96150e9df196dc480b 628 SUPERFAMILY SSF52467 193 374 7.58E-42 T 10-11-2016 IPR029035 DHS-like NAD/FAD-binding domain A4G23_RS01340 0c58af651ed5bc96150e9df196dc480b 628 Gene3D G3DSA:3.40.50.1220 218 371 3.5E-41 T 10-11-2016 IPR029035 DHS-like NAD/FAD-binding domain A4G23_RS01340 0c58af651ed5bc96150e9df196dc480b 628 Gene3D G3DSA:3.40.50.970 396 614 5.2E-51 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS01340 0c58af651ed5bc96150e9df196dc480b 628 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 227 360 8.0E-33 T 10-11-2016 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 A4G23_RS01340 0c58af651ed5bc96150e9df196dc480b 628 Gene3D G3DSA:3.40.50.970 8 217 2.3E-55 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS01340 0c58af651ed5bc96150e9df196dc480b 628 SUPERFAMILY SSF52518 10 218 1.13E-27 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS01340 0c58af651ed5bc96150e9df196dc480b 628 TIGRFAM TIGR04377 myo_inos_iolD: 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase 11 624 9.5E-260 T 10-11-2016 IPR030817 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase GO:0016823|GO:0019310|GO:0030976 KEGG: 00562+3.7.1.22 A4G23_RS01340 0c58af651ed5bc96150e9df196dc480b 628 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 13 205 2.8E-32 T 10-11-2016 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 A4G23_RS01320 20ffc962dbfac0c1df2abce66f27ec2d 307 SUPERFAMILY SSF50494 123 300 2.1E-41 T 10-11-2016 IPR009003 Peptidase S1, PA clan A4G23_RS01320 20ffc962dbfac0c1df2abce66f27ec2d 307 Pfam PF00089 Trypsin 145 299 1.8E-6 T 10-11-2016 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 A4G23_RS01320 20ffc962dbfac0c1df2abce66f27ec2d 307 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 257 268 - T 10-11-2016 IPR033116 Serine proteases, trypsin family, serine active site A4G23_RS01320 20ffc962dbfac0c1df2abce66f27ec2d 307 Gene3D G3DSA:2.40.10.10 117 204 4.8E-29 T 10-11-2016 A4G23_RS01320 20ffc962dbfac0c1df2abce66f27ec2d 307 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 147 152 - T 10-11-2016 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 A4G23_RS01320 20ffc962dbfac0c1df2abce66f27ec2d 307 Gene3D G3DSA:2.40.10.10 205 294 1.3E-30 T 10-11-2016 A4G23_RS01320 20ffc962dbfac0c1df2abce66f27ec2d 307 Pfam PF02983 Alpha-lytic protease prodomain 47 100 6.6E-10 T 10-11-2016 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 A4G23_RS01320 20ffc962dbfac0c1df2abce66f27ec2d 307 PIRSF PIRSF001134 10 307 1.9E-96 T 10-11-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A4G23_RS01320 20ffc962dbfac0c1df2abce66f27ec2d 307 Gene3D G3DSA:3.30.300.50 47 111 4.4E-7 T 10-11-2016 A4G23_RS01320 20ffc962dbfac0c1df2abce66f27ec2d 307 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 272 286 1.2E-49 T 10-11-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A4G23_RS01320 20ffc962dbfac0c1df2abce66f27ec2d 307 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 145 159 1.2E-49 T 10-11-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A4G23_RS01320 20ffc962dbfac0c1df2abce66f27ec2d 307 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 228 245 1.2E-49 T 10-11-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A4G23_RS01320 20ffc962dbfac0c1df2abce66f27ec2d 307 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 248 271 1.2E-49 T 10-11-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A4G23_RS01320 20ffc962dbfac0c1df2abce66f27ec2d 307 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 207 227 1.2E-49 T 10-11-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A4G23_RS12160 e97a31dee19f68a67346281ac0885a6c 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 190 208 2.3E-27 T 10-11-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A4G23_RS12160 e97a31dee19f68a67346281ac0885a6c 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 2.3E-27 T 10-11-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A4G23_RS12160 e97a31dee19f68a67346281ac0885a6c 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 221 242 2.3E-27 T 10-11-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A4G23_RS12160 e97a31dee19f68a67346281ac0885a6c 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 2.3E-27 T 10-11-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A4G23_RS12160 e97a31dee19f68a67346281ac0885a6c 466 Gene3D G3DSA:3.40.50.620 20 303 3.0E-96 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS12160 e97a31dee19f68a67346281ac0885a6c 466 SMART SM00840 341 403 6.5E-16 T 10-11-2016 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 A4G23_RS12160 e97a31dee19f68a67346281ac0885a6c 466 Pfam PF09190 DALR domain 341 394 1.2E-10 T 10-11-2016 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 A4G23_RS12160 e97a31dee19f68a67346281ac0885a6c 466 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 464 35.781 T 10-11-2016 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 A4G23_RS12160 e97a31dee19f68a67346281ac0885a6c 466 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 4 462 7.4E-140 T 10-11-2016 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 A4G23_RS12160 e97a31dee19f68a67346281ac0885a6c 466 Gene3D G3DSA:1.20.120.640 304 393 5.1E-19 T 10-11-2016 A4G23_RS12160 e97a31dee19f68a67346281ac0885a6c 466 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 16 310 4.4E-119 T 10-11-2016 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 A4G23_RS12160 e97a31dee19f68a67346281ac0885a6c 466 SUPERFAMILY SSF47323 331 463 2.75E-32 T 10-11-2016 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4G23_RS12160 e97a31dee19f68a67346281ac0885a6c 466 SUPERFAMILY SSF52374 4 309 1.07E-87 T 10-11-2016 A4G23_RS23345 554e1959983a0efabd0864b6d801e5a7 162 PRINTS PR00598 Bacterial regulatory protein MarR family signature 134 154 4.1E-10 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS23345 554e1959983a0efabd0864b6d801e5a7 162 PRINTS PR00598 Bacterial regulatory protein MarR family signature 104 120 4.1E-10 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS23345 554e1959983a0efabd0864b6d801e5a7 162 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 84 4.1E-10 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS23345 554e1959983a0efabd0864b6d801e5a7 162 PRINTS PR00598 Bacterial regulatory protein MarR family signature 85 100 4.1E-10 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS23345 554e1959983a0efabd0864b6d801e5a7 162 ProSitePatterns PS01117 MarR-type HTH domain signature. 83 117 - T 10-11-2016 IPR023187 Transcriptional regulator MarR-type, conserved site A4G23_RS23345 554e1959983a0efabd0864b6d801e5a7 162 Pfam PF12802 MarR family 48 108 1.2E-10 T 10-11-2016 A4G23_RS23345 554e1959983a0efabd0864b6d801e5a7 162 SMART SM00347 43 144 5.0E-21 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS23345 554e1959983a0efabd0864b6d801e5a7 162 Gene3D G3DSA:1.10.10.10 9 159 6.0E-38 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS23345 554e1959983a0efabd0864b6d801e5a7 162 SUPERFAMILY SSF46785 9 158 7.65E-33 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS21825 4cb20d7ba0050265e6276555f5d695b2 328 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS21825 4cb20d7ba0050265e6276555f5d695b2 328 Pfam PF00005 ABC transporter 21 163 8.0E-27 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS21825 4cb20d7ba0050265e6276555f5d695b2 328 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 12 308 7.3E-111 T 10-11-2016 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 A4G23_RS21825 4cb20d7ba0050265e6276555f5d695b2 328 Gene3D G3DSA:3.40.50.300 3 230 1.4E-69 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS21825 4cb20d7ba0050265e6276555f5d695b2 328 Pfam PF13732 Domain of unknown function (DUF4162) 217 306 6.4E-7 T 10-11-2016 IPR025302 Domain of unknown function DUF4162 A4G23_RS21825 4cb20d7ba0050265e6276555f5d695b2 328 SMART SM00382 29 212 1.8E-9 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS21825 4cb20d7ba0050265e6276555f5d695b2 328 SUPERFAMILY SSF52540 4 226 1.07E-60 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS12905 8e15941eea3a1329598ed9916ed4b188 82 Gene3D G3DSA:3.30.1280.10 3 81 2.6E-33 T 10-11-2016 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A4G23_RS12905 8e15941eea3a1329598ed9916ed4b188 82 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 2 79 21.84 T 10-11-2016 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A4G23_RS12905 8e15941eea3a1329598ed9916ed4b188 82 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 4 81 3.4E-22 T 10-11-2016 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A4G23_RS12905 8e15941eea3a1329598ed9916ed4b188 82 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 10 80 1.0E-31 T 10-11-2016 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A4G23_RS12905 8e15941eea3a1329598ed9916ed4b188 82 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 4 78 2.0E-28 T 10-11-2016 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A4G23_RS12905 8e15941eea3a1329598ed9916ed4b188 82 SUPERFAMILY SSF82697 3 81 1.03E-25 T 10-11-2016 A4G23_RS15300 8ae9618ea9a3864903603a79489f6e2e 266 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 34 47 - T 10-11-2016 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4G23_RS15300 8ae9618ea9a3864903603a79489f6e2e 266 Gene3D G3DSA:3.20.20.20 1 263 2.8E-105 T 10-11-2016 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4G23_RS15300 8ae9618ea9a3864903603a79489f6e2e 266 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 1 260 4.8E-91 T 10-11-2016 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 A4G23_RS15300 8ae9618ea9a3864903603a79489f6e2e 266 SUPERFAMILY SSF51717 1 261 5.89E-92 T 10-11-2016 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4G23_RS15300 8ae9618ea9a3864903603a79489f6e2e 266 Pfam PF00809 Pterin binding enzyme 1 246 2.4E-86 T 10-11-2016 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4G23_RS24575 3c6c734bd14ac2ec637f931edcb4eb2a 180 SUPERFAMILY SSF55729 5 170 1.37E-28 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS24575 3c6c734bd14ac2ec637f931edcb4eb2a 180 Pfam PF13302 Acetyltransferase (GNAT) domain 12 148 1.3E-14 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS24575 3c6c734bd14ac2ec637f931edcb4eb2a 180 Gene3D G3DSA:3.40.630.30 4 178 1.1E-30 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS07570 4cac5446e4c4ec5eadea083a363481ed 448 Gene3D G3DSA:3.90.226.10 249 448 4.9E-29 T 10-11-2016 IPR029045 ClpP/crotonase-like domain A4G23_RS07570 4cac5446e4c4ec5eadea083a363481ed 448 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 182 193 2.8E-13 T 10-11-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 A4G23_RS07570 4cac5446e4c4ec5eadea083a363481ed 448 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 116 134 2.8E-13 T 10-11-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 A4G23_RS07570 4cac5446e4c4ec5eadea083a363481ed 448 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 82 96 2.8E-13 T 10-11-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 A4G23_RS07570 4cac5446e4c4ec5eadea083a363481ed 448 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 153 170 2.8E-13 T 10-11-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 A4G23_RS07570 4cac5446e4c4ec5eadea083a363481ed 448 Gene3D G3DSA:3.90.226.10 4 230 4.1E-37 T 10-11-2016 IPR029045 ClpP/crotonase-like domain A4G23_RS07570 4cac5446e4c4ec5eadea083a363481ed 448 SUPERFAMILY SSF52096 251 448 1.61E-45 T 10-11-2016 IPR029045 ClpP/crotonase-like domain A4G23_RS07570 4cac5446e4c4ec5eadea083a363481ed 448 Pfam PF01039 Carboxyl transferase domain 310 426 2.0E-10 T 10-11-2016 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4G23_RS07570 4cac5446e4c4ec5eadea083a363481ed 448 Pfam PF01039 Carboxyl transferase domain 54 206 6.9E-17 T 10-11-2016 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4G23_RS07570 4cac5446e4c4ec5eadea083a363481ed 448 SUPERFAMILY SSF52096 4 229 2.64E-44 T 10-11-2016 IPR029045 ClpP/crotonase-like domain A4G23_RS20360 d237201059dd22e66f785dd53cca6016 382 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 124 135 - T 10-11-2016 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4G23_RS20360 d237201059dd22e66f785dd53cca6016 382 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 317 345 - T 10-11-2016 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4G23_RS20360 d237201059dd22e66f785dd53cca6016 382 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 15 374 1.8E-104 T 10-11-2016 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4G23_RS20360 d237201059dd22e66f785dd53cca6016 382 PIRSF PIRSF039102 12 380 2.9E-109 T 10-11-2016 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4G23_RS20360 d237201059dd22e66f785dd53cca6016 382 Gene3D G3DSA:3.40.50.20 13 146 7.6E-37 T 10-11-2016 IPR016185 Pre-ATP-grasp domain A4G23_RS20360 d237201059dd22e66f785dd53cca6016 382 Gene3D G3DSA:3.30.470.20 247 377 2.7E-47 T 10-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 A4G23_RS20360 d237201059dd22e66f785dd53cca6016 382 SUPERFAMILY SSF52440 13 155 3.93E-34 T 10-11-2016 IPR016185 Pre-ATP-grasp domain A4G23_RS20360 d237201059dd22e66f785dd53cca6016 382 Pfam PF01820 D-ala D-ala ligase N-terminus 15 147 1.3E-33 T 10-11-2016 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4G23_RS20360 d237201059dd22e66f785dd53cca6016 382 Gene3D G3DSA:3.30.1490.20 191 244 9.6E-23 T 10-11-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A4G23_RS20360 d237201059dd22e66f785dd53cca6016 382 SUPERFAMILY SSF56059 157 376 4.6E-56 T 10-11-2016 A4G23_RS20360 d237201059dd22e66f785dd53cca6016 382 Pfam PF07478 D-ala D-ala ligase C-terminus 165 372 2.5E-66 T 10-11-2016 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4G23_RS20360 d237201059dd22e66f785dd53cca6016 382 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 14 375 41.395 T 10-11-2016 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4G23_RS07565 4fe2b0de481cff90aeaba4439877497f 501 Gene3D G3DSA:3.30.300.30 404 499 1.2E-29 T 10-11-2016 A4G23_RS07565 4fe2b0de481cff90aeaba4439877497f 501 Pfam PF00501 AMP-binding enzyme 15 407 6.1E-81 T 10-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A4G23_RS07565 4fe2b0de481cff90aeaba4439877497f 501 ProSitePatterns PS00455 Putative AMP-binding domain signature. 157 168 - T 10-11-2016 IPR020845 AMP-binding, conserved site A4G23_RS07565 4fe2b0de481cff90aeaba4439877497f 501 Gene3D G3DSA:3.40.50.980 13 161 4.3E-23 T 10-11-2016 A4G23_RS07565 4fe2b0de481cff90aeaba4439877497f 501 Gene3D G3DSA:3.40.50.980 162 323 8.3E-33 T 10-11-2016 A4G23_RS07565 4fe2b0de481cff90aeaba4439877497f 501 SUPERFAMILY SSF56801 14 499 7.72E-123 T 10-11-2016 A4G23_RS07565 4fe2b0de481cff90aeaba4439877497f 501 Gene3D G3DSA:2.30.38.10 324 400 3.0E-26 T 10-11-2016 A4G23_RS07565 4fe2b0de481cff90aeaba4439877497f 501 Pfam PF13193 AMP-binding enzyme C-terminal domain 417 493 3.6E-19 T 10-11-2016 IPR025110 AMP-binding enzyme C-terminal domain A4G23_RS12575 f850c8cae6efc2532422696e9218bdb4 239 SMART SM00014 70 181 3.1E-13 T 10-11-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A4G23_RS12575 f850c8cae6efc2532422696e9218bdb4 239 SUPERFAMILY SSF48317 7 183 1.14E-33 T 10-11-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A4G23_RS12575 f850c8cae6efc2532422696e9218bdb4 239 Gene3D G3DSA:1.20.144.10 12 180 2.9E-29 T 10-11-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A4G23_RS12575 f850c8cae6efc2532422696e9218bdb4 239 Pfam PF01569 PAP2 superfamily 77 181 1.9E-19 T 10-11-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A4G23_RS21225 07cc085539565494e4a12ece231d9e5b 505 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 14 455 68.801 T 10-11-2016 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 A4G23_RS21225 07cc085539565494e4a12ece231d9e5b 505 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 15 450 4.9E-155 T 10-11-2016 IPR005839 Methylthiotransferase GO:0016740|GO:0043412|GO:0051539 A4G23_RS21225 07cc085539565494e4a12ece231d9e5b 505 SMART SM00729 158 377 3.3E-60 T 10-11-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 A4G23_RS21225 07cc085539565494e4a12ece231d9e5b 505 SUPERFAMILY SSF102114 144 384 1.83E-59 T 10-11-2016 A4G23_RS21225 07cc085539565494e4a12ece231d9e5b 505 Gene3D G3DSA:3.80.30.20 158 389 9.6E-85 T 10-11-2016 IPR023404 Radical SAM, alpha/beta horseshoe A4G23_RS21225 07cc085539565494e4a12ece231d9e5b 505 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 16 451 3.6E-149 T 10-11-2016 A4G23_RS21225 07cc085539565494e4a12ece231d9e5b 505 Pfam PF00919 Uncharacterized protein family UPF0004 16 115 9.3E-28 T 10-11-2016 IPR013848 Methylthiotransferase, N-terminal GO:0003824|GO:0009451|GO:0051539 A4G23_RS21225 07cc085539565494e4a12ece231d9e5b 505 Pfam PF04055 Radical SAM superfamily 162 332 1.7E-29 T 10-11-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 A4G23_RS21225 07cc085539565494e4a12ece231d9e5b 505 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 162 182 - T 10-11-2016 IPR020612 Methylthiotransferase, conserved site GO:0051539 A4G23_RS11495 38e610155728e2bde88ca938b4ce5270 251 SUPERFAMILY SSF53697 7 213 1.47E-21 T 10-11-2016 A4G23_RS11495 38e610155728e2bde88ca938b4ce5270 251 Pfam PF13580 SIS domain 9 146 1.1E-37 T 10-11-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 A4G23_RS11495 38e610155728e2bde88ca938b4ce5270 251 Gene3D G3DSA:3.40.50.10490 6 246 1.5E-67 T 10-11-2016 A4G23_RS06205 354da237409fedbc9fa23692ab42023d 358 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 38 1.2E-16 T 10-11-2016 IPR019933 DivIVA domain A4G23_RS06205 354da237409fedbc9fa23692ab42023d 358 Pfam PF05103 DivIVA protein 3 65 4.3E-14 T 10-11-2016 IPR007793 DivIVA family A4G23_RS24965 186fc78cef9b6b99fccf114346f577a0 845 SMART SM00387 723 833 6.9E-30 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS24965 186fc78cef9b6b99fccf114346f577a0 845 Gene3D G3DSA:3.30.565.10 670 835 6.7E-37 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS24965 186fc78cef9b6b99fccf114346f577a0 845 Gene3D G3DSA:1.20.120.620 381 477 4.1E-13 T 10-11-2016 A4G23_RS24965 186fc78cef9b6b99fccf114346f577a0 845 SMART SM00388 615 683 1.2E-17 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS24965 186fc78cef9b6b99fccf114346f577a0 845 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 3 211 3.4E-100 T 10-11-2016 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 A4G23_RS24965 186fc78cef9b6b99fccf114346f577a0 845 Pfam PF00582 Universal stress protein family 232 346 1.1E-6 T 10-11-2016 IPR006016 UspA GO:0006950 A4G23_RS24965 186fc78cef9b6b99fccf114346f577a0 845 SUPERFAMILY SSF52402 232 348 4.49E-8 T 10-11-2016 A4G23_RS24965 186fc78cef9b6b99fccf114346f577a0 845 PRINTS PR00344 Bacterial sensor protein C-terminal signature 817 830 2.3E-11 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS24965 186fc78cef9b6b99fccf114346f577a0 845 PRINTS PR00344 Bacterial sensor protein C-terminal signature 793 811 2.3E-11 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS24965 186fc78cef9b6b99fccf114346f577a0 845 PRINTS PR00344 Bacterial sensor protein C-terminal signature 760 774 2.3E-11 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS24965 186fc78cef9b6b99fccf114346f577a0 845 Pfam PF13493 Domain of unknown function (DUF4118) 383 488 9.0E-20 T 10-11-2016 IPR025201 Sensor protein KdpD, transmembrane domain A4G23_RS24965 186fc78cef9b6b99fccf114346f577a0 845 Gene3D G3DSA:1.10.287.130 606 669 5.6E-18 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS24965 186fc78cef9b6b99fccf114346f577a0 845 Pfam PF00512 His Kinase A (phospho-acceptor) domain 616 683 8.2E-17 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS24965 186fc78cef9b6b99fccf114346f577a0 845 Gene3D G3DSA:3.40.50.620 230 349 2.5E-9 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS24965 186fc78cef9b6b99fccf114346f577a0 845 SUPERFAMILY SSF47384 606 683 3.92E-16 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS24965 186fc78cef9b6b99fccf114346f577a0 845 Gene3D G3DSA:3.40.50.300 2 210 3.3E-99 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS24965 186fc78cef9b6b99fccf114346f577a0 845 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 724 832 3.1E-17 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS24965 186fc78cef9b6b99fccf114346f577a0 845 SUPERFAMILY SSF55874 673 834 1.02E-35 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS14840 1ba36295bab0baedd3fec5532f18d610 224 Gene3D G3DSA:1.10.10.10 146 222 6.5E-27 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS14840 1ba36295bab0baedd3fec5532f18d610 224 SMART SM00100 10 128 3.7E-27 T 10-11-2016 IPR000595 Cyclic nucleotide-binding domain A4G23_RS14840 1ba36295bab0baedd3fec5532f18d610 224 SUPERFAMILY SSF46785 145 222 2.93E-19 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS14840 1ba36295bab0baedd3fec5532f18d610 224 Pfam PF00027 Cyclic nucleotide-binding domain 29 110 5.1E-26 T 10-11-2016 IPR000595 Cyclic nucleotide-binding domain A4G23_RS14840 1ba36295bab0baedd3fec5532f18d610 224 Gene3D G3DSA:2.60.120.10 2 145 3.3E-41 T 10-11-2016 IPR014710 RmlC-like jelly roll fold A4G23_RS14840 1ba36295bab0baedd3fec5532f18d610 224 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 78 95 - T 10-11-2016 IPR018488 Cyclic nucleotide-binding, conserved site A4G23_RS14840 1ba36295bab0baedd3fec5532f18d610 224 SUPERFAMILY SSF51206 3 142 8.51E-40 T 10-11-2016 IPR018490 Cyclic nucleotide-binding-like A4G23_RS14840 1ba36295bab0baedd3fec5532f18d610 224 SMART SM00419 167 215 2.1E-13 T 10-11-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A4G23_RS14840 1ba36295bab0baedd3fec5532f18d610 224 Pfam PF13545 Crp-like helix-turn-helix domain 148 221 4.3E-17 T 10-11-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A4G23_RS14840 1ba36295bab0baedd3fec5532f18d610 224 PRINTS PR00103 cAMP-dependent protein kinase signature 31 45 2.4E-6 T 10-11-2016 A4G23_RS14840 1ba36295bab0baedd3fec5532f18d610 224 PRINTS PR00103 cAMP-dependent protein kinase signature 46 60 2.4E-6 T 10-11-2016 A4G23_RS14840 1ba36295bab0baedd3fec5532f18d610 224 PRINTS PR00103 cAMP-dependent protein kinase signature 76 85 2.4E-6 T 10-11-2016 A4G23_RS14840 1ba36295bab0baedd3fec5532f18d610 224 PRINTS PR00103 cAMP-dependent protein kinase signature 88 99 2.4E-6 T 10-11-2016 A4G23_RS03670 9823872ed47b06637f6fff75adf344ba 420 PIRSF PIRSF001549 1 419 2.6E-101 T 10-11-2016 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 A4G23_RS03670 9823872ed47b06637f6fff75adf344ba 420 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 5 407 1.2E-131 T 10-11-2016 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 A4G23_RS03670 9823872ed47b06637f6fff75adf344ba 420 Gene3D G3DSA:3.30.930.10 219 319 3.3E-81 T 10-11-2016 A4G23_RS03670 9823872ed47b06637f6fff75adf344ba 420 Gene3D G3DSA:3.30.930.10 3 185 3.3E-81 T 10-11-2016 A4G23_RS03670 9823872ed47b06637f6fff75adf344ba 420 Gene3D G3DSA:3.40.50.800 326 417 2.9E-27 T 10-11-2016 IPR004154 Anticodon-binding A4G23_RS03670 9823872ed47b06637f6fff75adf344ba 420 Pfam PF13393 Histidyl-tRNA synthetase 9 309 1.4E-43 T 10-11-2016 A4G23_RS03670 9823872ed47b06637f6fff75adf344ba 420 SUPERFAMILY SSF52954 325 419 2.42E-22 T 10-11-2016 IPR004154 Anticodon-binding A4G23_RS03670 9823872ed47b06637f6fff75adf344ba 420 SUPERFAMILY SSF55681 4 315 1.45E-80 T 10-11-2016 A4G23_RS03670 9823872ed47b06637f6fff75adf344ba 420 Pfam PF03129 Anticodon binding domain 329 417 3.2E-11 T 10-11-2016 IPR004154 Anticodon-binding A4G23_RS03670 9823872ed47b06637f6fff75adf344ba 420 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 2 417 30.878 T 10-11-2016 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 A4G23_RS27170 b8d0ba8517ae5d8c3ba011cc5b48b303 330 PRINTS PR00412 Epoxide hydrolase signature 254 270 1.4E-5 T 10-11-2016 IPR000639 Epoxide hydrolase-like GO:0003824 A4G23_RS27170 b8d0ba8517ae5d8c3ba011cc5b48b303 330 PRINTS PR00412 Epoxide hydrolase signature 79 94 1.4E-5 T 10-11-2016 IPR000639 Epoxide hydrolase-like GO:0003824 A4G23_RS27170 b8d0ba8517ae5d8c3ba011cc5b48b303 330 PRINTS PR00412 Epoxide hydrolase signature 137 150 1.4E-5 T 10-11-2016 IPR000639 Epoxide hydrolase-like GO:0003824 A4G23_RS27170 b8d0ba8517ae5d8c3ba011cc5b48b303 330 PRINTS PR00412 Epoxide hydrolase signature 287 309 1.4E-5 T 10-11-2016 IPR000639 Epoxide hydrolase-like GO:0003824 A4G23_RS27170 b8d0ba8517ae5d8c3ba011cc5b48b303 330 PRINTS PR00412 Epoxide hydrolase signature 123 136 1.4E-5 T 10-11-2016 IPR000639 Epoxide hydrolase-like GO:0003824 A4G23_RS27170 b8d0ba8517ae5d8c3ba011cc5b48b303 330 Gene3D G3DSA:3.40.50.1820 19 312 8.9E-37 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS27170 b8d0ba8517ae5d8c3ba011cc5b48b303 330 Pfam PF12697 Alpha/beta hydrolase family 56 304 3.8E-10 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS27170 b8d0ba8517ae5d8c3ba011cc5b48b303 330 SUPERFAMILY SSF53474 48 311 2.4E-38 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS05705 59471cb262101383d0c0b5e3f2f943f4 141 SUPERFAMILY SSF50022 42 138 3.14E-28 T 10-11-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A4G23_RS05705 59471cb262101383d0c0b5e3f2f943f4 141 Pfam PF00355 Rieske [2Fe-2S] domain 48 128 5.6E-16 T 10-11-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A4G23_RS05705 59471cb262101383d0c0b5e3f2f943f4 141 Gene3D G3DSA:2.102.10.10 7 137 3.0E-29 T 10-11-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A4G23_RS05705 59471cb262101383d0c0b5e3f2f943f4 141 PRINTS PR00162 Rieske 2Fe-2S subunit signature 99 111 6.3E-9 T 10-11-2016 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 A4G23_RS05705 59471cb262101383d0c0b5e3f2f943f4 141 PRINTS PR00162 Rieske 2Fe-2S subunit signature 112 124 6.3E-9 T 10-11-2016 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 A4G23_RS05705 59471cb262101383d0c0b5e3f2f943f4 141 PRINTS PR00162 Rieske 2Fe-2S subunit signature 79 90 6.3E-9 T 10-11-2016 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 A4G23_RS10090 e372a29233eadb96e75d9f2b3d5c70c3 447 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 328 428 3.6E-26 T 10-11-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A4G23_RS10090 e372a29233eadb96e75d9f2b3d5c70c3 447 SMART SM00984 328 429 4.5E-44 T 10-11-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A4G23_RS10090 e372a29233eadb96e75d9f2b3d5c70c3 447 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 210 302 6.8E-30 T 10-11-2016 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A4G23_RS10090 e372a29233eadb96e75d9f2b3d5c70c3 447 SUPERFAMILY SSF52413 322 438 3.4E-34 T 10-11-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A4G23_RS10090 e372a29233eadb96e75d9f2b3d5c70c3 447 SUPERFAMILY SSF48179 210 306 3.91E-26 T 10-11-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A4G23_RS10090 e372a29233eadb96e75d9f2b3d5c70c3 447 PIRSF PIRSF000124 3 444 9.0E-112 T 10-11-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A4G23_RS10090 e372a29233eadb96e75d9f2b3d5c70c3 447 Gene3D G3DSA:3.40.50.720 240 445 3.0E-63 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS10090 e372a29233eadb96e75d9f2b3d5c70c3 447 PIRSF PIRSF500134 3 447 1.3E-151 T 10-11-2016 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00500+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346 A4G23_RS10090 e372a29233eadb96e75d9f2b3d5c70c3 447 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 4 425 2.2E-125 T 10-11-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A4G23_RS10090 e372a29233eadb96e75d9f2b3d5c70c3 447 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 4 192 4.6E-58 T 10-11-2016 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A4G23_RS10090 e372a29233eadb96e75d9f2b3d5c70c3 447 SUPERFAMILY SSF51735 4 197 1.2E-46 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS10090 e372a29233eadb96e75d9f2b3d5c70c3 447 Gene3D G3DSA:3.40.50.720 4 212 1.8E-68 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS10090 e372a29233eadb96e75d9f2b3d5c70c3 447 Gene3D G3DSA:1.20.5.100 213 238 2.0E-16 T 10-11-2016 A4G23_RS23690 eb2c7a704ca08066ecede6b5b9bf003a 512 Gene3D G3DSA:3.30.70.20 194 235 1.3E-24 T 10-11-2016 A4G23_RS23690 eb2c7a704ca08066ecede6b5b9bf003a 512 SUPERFAMILY SSF54862 1 485 4.08E-152 T 10-11-2016 A4G23_RS23690 eb2c7a704ca08066ecede6b5b9bf003a 512 Pfam PF14711 Respiratory nitrate reductase beta C-terminal 358 438 3.3E-25 T 10-11-2016 IPR029263 Respiratory nitrate reductase beta, C-terminal KEGG: 00910+1.7.99.4 A4G23_RS23690 eb2c7a704ca08066ecede6b5b9bf003a 512 Pfam PF13247 4Fe-4S dicluster domain 176 270 3.7E-35 T 10-11-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4G23_RS23690 eb2c7a704ca08066ecede6b5b9bf003a 512 TIGRFAM TIGR01660 narH: nitrate reductase, beta subunit 1 479 1.9E-219 T 10-11-2016 IPR006547 Nitrate reductase, beta subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.99.4 A4G23_RS23690 eb2c7a704ca08066ecede6b5b9bf003a 512 Gene3D G3DSA:1.10.3650.10 359 437 3.6E-25 T 10-11-2016 IPR029263 Respiratory nitrate reductase beta, C-terminal KEGG: 00910+1.7.99.4 A4G23_RS23690 eb2c7a704ca08066ecede6b5b9bf003a 512 Gene3D G3DSA:3.30.70.20 439 468 5.0E-64 T 10-11-2016 A4G23_RS23690 eb2c7a704ca08066ecede6b5b9bf003a 512 Gene3D G3DSA:3.30.70.20 236 358 5.0E-64 T 10-11-2016 A4G23_RS23690 eb2c7a704ca08066ecede6b5b9bf003a 512 Gene3D G3DSA:3.30.70.20 4 53 1.9E-18 T 10-11-2016 A4G23_RS23690 eb2c7a704ca08066ecede6b5b9bf003a 512 Gene3D G3DSA:3.30.70.20 173 193 1.9E-18 T 10-11-2016 A4G23_RS09425 fab5e830ecfdc3498112a993114d515b 77 Pfam PF00367 phosphotransferase system, EIIB 7 39 1.5E-12 T 10-11-2016 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 A4G23_RS09425 fab5e830ecfdc3498112a993114d515b 77 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 4 63 1.4E-16 T 10-11-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 A4G23_RS09425 fab5e830ecfdc3498112a993114d515b 77 Gene3D G3DSA:3.30.1360.60 3 77 4.2E-27 T 10-11-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 A4G23_RS09425 fab5e830ecfdc3498112a993114d515b 77 SUPERFAMILY SSF55604 5 76 5.1E-21 T 10-11-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 A4G23_RS09930 bc0f4476083a911530f5e437060bfc34 485 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 5 477 49.97 T 10-11-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A4G23_RS09930 bc0f4476083a911530f5e437060bfc34 485 SUPERFAMILY SSF52283 406 485 1.42E-115 T 10-11-2016 A4G23_RS09930 bc0f4476083a911530f5e437060bfc34 485 SUPERFAMILY SSF52283 7 157 1.42E-115 T 10-11-2016 A4G23_RS09930 bc0f4476083a911530f5e437060bfc34 485 SUPERFAMILY SSF52283 195 242 1.42E-115 T 10-11-2016 A4G23_RS09930 bc0f4476083a911530f5e437060bfc34 485 SMART SM00996 9 484 0.0 T 10-11-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A4G23_RS09930 bc0f4476083a911530f5e437060bfc34 485 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 9 484 3.3E-149 T 10-11-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A4G23_RS09930 bc0f4476083a911530f5e437060bfc34 485 SUPERFAMILY SSF51735 243 405 4.14E-78 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS09930 bc0f4476083a911530f5e437060bfc34 485 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 265 281 - T 10-11-2016 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A4G23_RS09930 bc0f4476083a911530f5e437060bfc34 485 SMART SM00997 243 405 2.7E-112 T 10-11-2016 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A4G23_RS09930 bc0f4476083a911530f5e437060bfc34 485 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 10 477 2.4E-193 T 10-11-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A4G23_RS09930 bc0f4476083a911530f5e437060bfc34 485 Gene3D G3DSA:3.40.50.1480 406 485 2.1E-149 T 10-11-2016 A4G23_RS09930 bc0f4476083a911530f5e437060bfc34 485 Gene3D G3DSA:3.40.50.1480 8 244 2.1E-149 T 10-11-2016 A4G23_RS09930 bc0f4476083a911530f5e437060bfc34 485 Gene3D G3DSA:3.40.50.720 245 404 5.4E-52 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS09930 bc0f4476083a911530f5e437060bfc34 485 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 81 95 - T 10-11-2016 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A4G23_RS09930 bc0f4476083a911530f5e437060bfc34 485 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 243 405 5.9E-84 T 10-11-2016 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A4G23_RS09930 bc0f4476083a911530f5e437060bfc34 485 PIRSF PIRSF001109 1 485 1.6E-194 T 10-11-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A4G23_RS10795 dc30f8543f6944409e87ceb393a3b7aa 348 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 168 173 - T 10-11-2016 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 A4G23_RS10795 dc30f8543f6944409e87ceb393a3b7aa 348 Gene3D G3DSA:2.40.10.10 148 227 5.5E-10 T 10-11-2016 A4G23_RS10795 dc30f8543f6944409e87ceb393a3b7aa 348 SUPERFAMILY SSF50494 141 333 5.12E-15 T 10-11-2016 IPR009003 Peptidase S1, PA clan A4G23_RS11945 9ce66f06eafdc38569d85a6ad2cef3e1 101 Pfam PF06013 Proteins of 100 residues with WXG 7 91 6.6E-10 T 10-11-2016 IPR010310 Type VII secretion system ESAT-6-like A4G23_RS11945 9ce66f06eafdc38569d85a6ad2cef3e1 101 SUPERFAMILY SSF140453 5 97 4.32E-16 T 10-11-2016 IPR010310 Type VII secretion system ESAT-6-like A4G23_RS11945 9ce66f06eafdc38569d85a6ad2cef3e1 101 Gene3D G3DSA:1.10.287.1060 6 97 1.1E-16 T 10-11-2016 A4G23_RS11945 9ce66f06eafdc38569d85a6ad2cef3e1 101 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 6 92 5.4E-13 T 10-11-2016 IPR010310 Type VII secretion system ESAT-6-like A4G23_RS18245 bc657bdffe21a8724097b71ffc67a229 459 Gene3D G3DSA:2.80.10.50 338 459 2.4E-23 T 10-11-2016 A4G23_RS18245 bc657bdffe21a8724097b71ffc67a229 459 SUPERFAMILY SSF50370 335 459 4.11E-26 T 10-11-2016 IPR000772 Ricin B, lectin domain A4G23_RS18245 bc657bdffe21a8724097b71ffc67a229 459 SUPERFAMILY SSF52266 25 306 1.15E-50 T 10-11-2016 IPR013830 SGNH hydrolase-type esterase domain A4G23_RS18245 bc657bdffe21a8724097b71ffc67a229 459 Pfam PF00652 Ricin-type beta-trefoil lectin domain 337 458 2.6E-17 T 10-11-2016 IPR000772 Ricin B, lectin domain A4G23_RS18245 bc657bdffe21a8724097b71ffc67a229 459 Gene3D G3DSA:3.40.50.1110 23 304 5.2E-40 T 10-11-2016 IPR013830 SGNH hydrolase-type esterase domain A4G23_RS18245 bc657bdffe21a8724097b71ffc67a229 459 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 31 297 1.5E-14 T 10-11-2016 IPR013830 SGNH hydrolase-type esterase domain A4G23_RS18245 bc657bdffe21a8724097b71ffc67a229 459 SMART SM00458 332 459 1.5E-11 T 10-11-2016 IPR000772 Ricin B, lectin domain A4G23_RS15645 eb3d63febdc56b9098334003581c0e07 456 Gene3D G3DSA:1.20.1250.20 262 448 6.3E-20 T 10-11-2016 A4G23_RS15645 eb3d63febdc56b9098334003581c0e07 456 PRINTS PR01036 Tetracycline resistance protein TetB signature 73 95 1.5E-5 T 10-11-2016 A4G23_RS15645 eb3d63febdc56b9098334003581c0e07 456 PRINTS PR01036 Tetracycline resistance protein TetB signature 135 159 1.5E-5 T 10-11-2016 A4G23_RS15645 eb3d63febdc56b9098334003581c0e07 456 PRINTS PR01036 Tetracycline resistance protein TetB signature 14 38 1.5E-5 T 10-11-2016 A4G23_RS15645 eb3d63febdc56b9098334003581c0e07 456 PRINTS PR01036 Tetracycline resistance protein TetB signature 105 125 1.5E-5 T 10-11-2016 A4G23_RS15645 eb3d63febdc56b9098334003581c0e07 456 Gene3D G3DSA:1.20.1250.20 11 193 2.1E-31 T 10-11-2016 A4G23_RS15645 eb3d63febdc56b9098334003581c0e07 456 SUPERFAMILY SSF103473 6 193 1.05E-63 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS15645 eb3d63febdc56b9098334003581c0e07 456 SUPERFAMILY SSF103473 246 448 1.05E-63 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS15645 eb3d63febdc56b9098334003581c0e07 456 Pfam PF07690 Major Facilitator Superfamily 15 407 7.7E-55 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS13605 216c20f7cbd1dc4aecd84360aec8d35c 78 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 3 76 20.546 T 10-11-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS13605 216c20f7cbd1dc4aecd84360aec8d35c 78 Gene3D G3DSA:4.10.640.10 11 75 1.3E-31 T 10-11-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS13605 216c20f7cbd1dc4aecd84360aec8d35c 78 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 23 73 3.0E-24 T 10-11-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS13605 216c20f7cbd1dc4aecd84360aec8d35c 78 Pfam PF01084 Ribosomal protein S18 21 71 9.7E-24 T 10-11-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS13605 216c20f7cbd1dc4aecd84360aec8d35c 78 ProSitePatterns PS00057 Ribosomal protein S18 signature. 24 47 - T 10-11-2016 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS13605 216c20f7cbd1dc4aecd84360aec8d35c 78 TIGRFAM TIGR00165 S18: ribosomal protein bS18 9 75 1.4E-29 T 10-11-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS13605 216c20f7cbd1dc4aecd84360aec8d35c 78 PRINTS PR00974 Ribosomal protein S18 family signature 63 73 8.4E-16 T 10-11-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS13605 216c20f7cbd1dc4aecd84360aec8d35c 78 PRINTS PR00974 Ribosomal protein S18 family signature 31 41 8.4E-16 T 10-11-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS13605 216c20f7cbd1dc4aecd84360aec8d35c 78 PRINTS PR00974 Ribosomal protein S18 family signature 41 48 8.4E-16 T 10-11-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS13605 216c20f7cbd1dc4aecd84360aec8d35c 78 PRINTS PR00974 Ribosomal protein S18 family signature 49 63 8.4E-16 T 10-11-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS13605 216c20f7cbd1dc4aecd84360aec8d35c 78 SUPERFAMILY SSF46911 5 75 7.32E-28 T 10-11-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS08925 ebd8f2d2c84315aa183ac2c839896149 419 SUPERFAMILY SSF52540 184 340 9.24E-13 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS08925 ebd8f2d2c84315aa183ac2c839896149 419 SUPERFAMILY SSF52540 47 150 9.24E-13 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS08925 ebd8f2d2c84315aa183ac2c839896149 419 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 48 337 1.3E-42 T 10-11-2016 IPR003959 ATPase, AAA-type, core GO:0005524 A4G23_RS08925 ebd8f2d2c84315aa183ac2c839896149 419 Gene3D G3DSA:3.40.50.300 1 338 4.1E-17 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS06060 1b967b9a0eeba3a7d9a82f72cc1b6e3c 197 Gene3D G3DSA:3.30.230.40 91 197 2.1E-28 T 10-11-2016 A4G23_RS06060 1b967b9a0eeba3a7d9a82f72cc1b6e3c 197 Gene3D G3DSA:3.30.230.40 3 89 9.9E-37 T 10-11-2016 A4G23_RS06060 1b967b9a0eeba3a7d9a82f72cc1b6e3c 197 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 32 176 2.3E-61 T 10-11-2016 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 A4G23_RS06060 1b967b9a0eeba3a7d9a82f72cc1b6e3c 197 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 62 75 - T 10-11-2016 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 A4G23_RS06060 1b967b9a0eeba3a7d9a82f72cc1b6e3c 197 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 158 170 - T 10-11-2016 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 A4G23_RS06060 1b967b9a0eeba3a7d9a82f72cc1b6e3c 197 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 3 197 41.182 T 10-11-2016 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 A4G23_RS06060 1b967b9a0eeba3a7d9a82f72cc1b6e3c 197 SUPERFAMILY SSF54211 3 86 1.14E-32 T 10-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold A4G23_RS06060 1b967b9a0eeba3a7d9a82f72cc1b6e3c 197 SUPERFAMILY SSF54211 88 181 7.59E-30 T 10-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold A4G23_RS05330 4a455fa4b8c6199d41d21c1a080fe8a3 684 PIRSF PIRSF001227 1 683 2.1E-214 T 10-11-2016 IPR014395 Penicillin acylase GO:0016811 A4G23_RS05330 4a455fa4b8c6199d41d21c1a080fe8a3 684 SUPERFAMILY SSF56235 3 678 4.89E-146 T 10-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal A4G23_RS05330 4a455fa4b8c6199d41d21c1a080fe8a3 684 Gene3D G3DSA:1.10.439.10 3 127 6.6E-37 T 10-11-2016 IPR023343 Penicillin amidase type, domain1 GO:0016811 A4G23_RS05330 4a455fa4b8c6199d41d21c1a080fe8a3 684 Pfam PF01804 Penicillin amidase 3 678 2.6E-182 T 10-11-2016 IPR002692 Penicillin/cephalosporin acylase GO:0016787|GO:0017000 A4G23_RS05330 4a455fa4b8c6199d41d21c1a080fe8a3 684 Gene3D G3DSA:3.60.20.10 128 247 2.2E-82 T 10-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal A4G23_RS05330 4a455fa4b8c6199d41d21c1a080fe8a3 684 Gene3D G3DSA:3.60.20.10 325 500 2.2E-82 T 10-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal A4G23_RS05330 4a455fa4b8c6199d41d21c1a080fe8a3 684 Gene3D G3DSA:2.30.120.10 248 312 3.7E-12 T 10-11-2016 A4G23_RS07920 4d887e1f0dc43ddd73294769d2f5e791 357 Pfam PF03060 Nitronate monooxygenase 3 340 2.9E-111 T 10-11-2016 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 A4G23_RS07920 4d887e1f0dc43ddd73294769d2f5e791 357 Gene3D G3DSA:3.20.20.70 2 332 2.2E-68 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS07920 4d887e1f0dc43ddd73294769d2f5e791 357 SUPERFAMILY SSF51412 9 345 8.39E-58 T 10-11-2016 A4G23_RS08575 283d2d92af7a7276c6abaa44fc789e9a 464 Pfam PF00589 Phage integrase family 239 426 4.8E-6 T 10-11-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A4G23_RS08575 283d2d92af7a7276c6abaa44fc789e9a 464 Gene3D G3DSA:1.10.443.10 239 442 5.0E-24 T 10-11-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 A4G23_RS08575 283d2d92af7a7276c6abaa44fc789e9a 464 SUPERFAMILY SSF56349 173 440 1.74E-26 T 10-11-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A4G23_RS19400 82e17974edf1d15def8d4f86c570f517 410 SMART SM00559 52 181 8.9E-42 T 10-11-2016 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571 A4G23_RS19400 82e17974edf1d15def8d4f86c570f517 410 Hamap MF_01875 Non-homologous end joining protein Ku [ku]. 1 253 30.294 T 10-11-2016 IPR009187 Non-homologous end joining protein Ku, prokaryotic type A4G23_RS19400 82e17974edf1d15def8d4f86c570f517 410 SUPERFAMILY SSF100939 2 254 1.0E-45 T 10-11-2016 IPR016194 SPOC-like, C-terminal domain A4G23_RS19400 82e17974edf1d15def8d4f86c570f517 410 Pfam PF02735 Ku70/Ku80 beta-barrel domain 11 190 5.0E-32 T 10-11-2016 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571 A4G23_RS19400 82e17974edf1d15def8d4f86c570f517 410 TIGRFAM TIGR02772 Ku_bact: Ku protein 1 255 1.9E-85 T 10-11-2016 IPR009187 Non-homologous end joining protein Ku, prokaryotic type A4G23_RS19400 82e17974edf1d15def8d4f86c570f517 410 Gene3D G3DSA:2.40.290.10 4 147 6.0E-11 T 10-11-2016 IPR016194 SPOC-like, C-terminal domain A4G23_RS14275 0d39285aba2ec54eb34d48f14d84b2ca 506 SUPERFAMILY SSF116726 409 477 7.46E-10 T 10-11-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A4G23_RS14275 0d39285aba2ec54eb34d48f14d84b2ca 506 Pfam PF00999 Sodium/hydrogen exchanger family 16 384 1.1E-50 T 10-11-2016 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A4G23_RS14275 0d39285aba2ec54eb34d48f14d84b2ca 506 Pfam PF02080 TrkA-C domain 414 477 2.2E-8 T 10-11-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A4G23_RS14275 0d39285aba2ec54eb34d48f14d84b2ca 506 Gene3D G3DSA:3.30.70.1450 411 478 1.4E-5 T 10-11-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A4G23_RS24265 f5860339c0633c4bed6aaab91d1d569e 218 Hamap MF_00664 Phosphatidylserine decarboxylase proenzyme [psd]. 17 218 32.255 T 10-11-2016 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 A4G23_RS24265 f5860339c0633c4bed6aaab91d1d569e 218 Pfam PF02666 Phosphatidylserine decarboxylase 59 212 9.8E-30 T 10-11-2016 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 A4G23_RS24265 f5860339c0633c4bed6aaab91d1d569e 218 TIGRFAM TIGR00164 PS_decarb_rel: phosphatidylserine decarboxylase homolog 45 217 8.5E-53 T 10-11-2016 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 A4G23_RS16060 49bf6151f592e54a20e42fe8dc1ae58c 444 Gene3D G3DSA:1.10.645.10 33 328 1.3E-68 T 10-11-2016 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16060 49bf6151f592e54a20e42fe8dc1ae58c 444 Gene3D G3DSA:1.10.645.10 372 437 1.3E-68 T 10-11-2016 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16060 49bf6151f592e54a20e42fe8dc1ae58c 444 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 79 90 - T 10-11-2016 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16060 49bf6151f592e54a20e42fe8dc1ae58c 444 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 38 444 47.312 T 10-11-2016 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16060 49bf6151f592e54a20e42fe8dc1ae58c 444 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 42 444 9.9E-176 T 10-11-2016 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16060 49bf6151f592e54a20e42fe8dc1ae58c 444 SUPERFAMILY SSF56762 52 444 3.92E-123 T 10-11-2016 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16060 49bf6151f592e54a20e42fe8dc1ae58c 444 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 159 444 5.3E-114 T 10-11-2016 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS25805 cc054e9842f9abab561a771cb6ae137c 722 SMART SM00267 279 451 9.0E-61 T 10-11-2016 IPR000160 GGDEF domain A4G23_RS25805 cc054e9842f9abab561a771cb6ae137c 722 SUPERFAMILY SSF55073 295 453 8.89E-43 T 10-11-2016 IPR029787 Nucleotide cyclase A4G23_RS25805 cc054e9842f9abab561a771cb6ae137c 722 SMART SM00052 461 712 6.5E-108 T 10-11-2016 IPR001633 EAL domain A4G23_RS25805 cc054e9842f9abab561a771cb6ae137c 722 SMART SM00086 540 579 260.0 T 10-11-2016 IPR001610 PAC motif A4G23_RS25805 cc054e9842f9abab561a771cb6ae137c 722 SMART SM00086 237 279 1.4E-4 T 10-11-2016 IPR001610 PAC motif A4G23_RS25805 cc054e9842f9abab561a771cb6ae137c 722 Gene3D G3DSA:3.30.70.270 291 457 2.7E-53 T 10-11-2016 A4G23_RS25805 cc054e9842f9abab561a771cb6ae137c 722 SUPERFAMILY SSF141868 468 715 6.54E-83 T 10-11-2016 IPR001633 EAL domain A4G23_RS25805 cc054e9842f9abab561a771cb6ae137c 722 Gene3D G3DSA:3.30.450.20 152 274 9.3E-26 T 10-11-2016 A4G23_RS25805 cc054e9842f9abab561a771cb6ae137c 722 SUPERFAMILY SSF55785 152 277 3.32E-24 T 10-11-2016 IPR000014 PAS domain A4G23_RS25805 cc054e9842f9abab561a771cb6ae137c 722 Gene3D G3DSA:3.20.20.450 465 717 6.8E-98 T 10-11-2016 IPR001633 EAL domain A4G23_RS25805 cc054e9842f9abab561a771cb6ae137c 722 Pfam PF08448 PAS fold 174 280 2.8E-13 T 10-11-2016 IPR013656 PAS fold-4 A4G23_RS25805 cc054e9842f9abab561a771cb6ae137c 722 SMART SM00091 164 230 2.1E-10 T 10-11-2016 IPR000014 PAS domain A4G23_RS25805 cc054e9842f9abab561a771cb6ae137c 722 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 162 282 1.4E-22 T 10-11-2016 IPR000014 PAS domain A4G23_RS25805 cc054e9842f9abab561a771cb6ae137c 722 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 288 450 2.7E-32 T 10-11-2016 IPR000160 GGDEF domain A4G23_RS25805 cc054e9842f9abab561a771cb6ae137c 722 Pfam PF00563 EAL domain 468 707 1.2E-71 T 10-11-2016 IPR001633 EAL domain A4G23_RS25805 cc054e9842f9abab561a771cb6ae137c 722 Pfam PF00990 Diguanylate cyclase, GGDEF domain 290 447 1.1E-42 T 10-11-2016 IPR000160 GGDEF domain A4G23_RS01440 884a264affc77212f3cc85a9ca1ede08 272 Gene3D G3DSA:3.40.190.10 26 101 7.2E-13 T 10-11-2016 A4G23_RS01440 884a264affc77212f3cc85a9ca1ede08 272 Gene3D G3DSA:3.40.190.10 132 166 8.8E-4 T 10-11-2016 A4G23_RS01440 884a264affc77212f3cc85a9ca1ede08 272 SUPERFAMILY SSF53850 10 195 1.47E-21 T 10-11-2016 A4G23_RS01440 884a264affc77212f3cc85a9ca1ede08 272 Pfam PF03466 LysR substrate binding domain 22 193 3.2E-21 T 10-11-2016 IPR005119 LysR, substrate-binding A4G23_RS13225 9d79b6bda1396603e01471c61f778a60 280 Pfam PF12804 MobA-like NTP transferase domain 6 148 5.3E-30 T 10-11-2016 IPR025877 MobA-like NTP transferase A4G23_RS13225 9d79b6bda1396603e01471c61f778a60 280 SUPERFAMILY SSF53448 4 185 5.41E-29 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS13225 9d79b6bda1396603e01471c61f778a60 280 Gene3D G3DSA:3.90.550.10 2 195 3.1E-42 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS25930 370be9bbb0424dffaa9f572b08d7afad 573 Gene3D G3DSA:1.20.140.10 232 394 1.7E-22 T 10-11-2016 A4G23_RS25930 370be9bbb0424dffaa9f572b08d7afad 573 SUPERFAMILY SSF56645 16 238 7.2E-26 T 10-11-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 A4G23_RS25930 370be9bbb0424dffaa9f572b08d7afad 573 SUPERFAMILY SSF47203 244 400 9.5E-27 T 10-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4G23_RS25930 370be9bbb0424dffaa9f572b08d7afad 573 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 245 392 1.8E-18 T 10-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4G23_RS25930 370be9bbb0424dffaa9f572b08d7afad 573 Gene3D G3DSA:1.10.540.10 17 134 6.2E-4 T 10-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 A4G23_RS25930 370be9bbb0424dffaa9f572b08d7afad 573 Gene3D G3DSA:2.40.110.10 136 231 2.3E-11 T 10-11-2016 A4G23_RS15230 8fc6b3d622470ba78d5f90a9fa861c7a 252 Gene3D G3DSA:1.10.1660.10 4 57 2.5E-25 T 10-11-2016 A4G23_RS15230 8fc6b3d622470ba78d5f90a9fa861c7a 252 Gene3D G3DSA:1.10.490.50 160 251 2.9E-33 T 10-11-2016 IPR012925 TipAS antibiotic-recognition domain A4G23_RS15230 8fc6b3d622470ba78d5f90a9fa861c7a 252 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 4 15 6.0E-9 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS15230 8fc6b3d622470ba78d5f90a9fa861c7a 252 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 28 6.0E-9 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS15230 8fc6b3d622470ba78d5f90a9fa861c7a 252 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 6.0E-9 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS15230 8fc6b3d622470ba78d5f90a9fa861c7a 252 SUPERFAMILY SSF89082 160 251 3.92E-28 T 10-11-2016 IPR012925 TipAS antibiotic-recognition domain A4G23_RS15230 8fc6b3d622470ba78d5f90a9fa861c7a 252 SUPERFAMILY SSF46955 4 104 1.87E-29 T 10-11-2016 IPR009061 Putative DNA-binding domain A4G23_RS15230 8fc6b3d622470ba78d5f90a9fa861c7a 252 Pfam PF07739 TipAS antibiotic-recognition domain 131 247 1.1E-37 T 10-11-2016 IPR012925 TipAS antibiotic-recognition domain A4G23_RS15230 8fc6b3d622470ba78d5f90a9fa861c7a 252 Pfam PF13411 MerR HTH family regulatory protein 4 70 6.5E-15 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS15230 8fc6b3d622470ba78d5f90a9fa861c7a 252 SMART SM00422 3 72 8.4E-29 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS15230 8fc6b3d622470ba78d5f90a9fa861c7a 252 ProSitePatterns PS00552 MerR-type HTH domain signature. 6 28 - T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS15230 8fc6b3d622470ba78d5f90a9fa861c7a 252 Gene3D G3DSA:1.10.1660.10 58 107 2.2E-10 T 10-11-2016 A4G23_RS21270 a92cc96d031985796555a8c272c14eee 500 Pfam PF01926 50S ribosome-binding GTPase 281 399 2.0E-20 T 10-11-2016 IPR006073 GTP binding domain GO:0005525 A4G23_RS21270 a92cc96d031985796555a8c272c14eee 500 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 84 439 2.0E-130 T 10-11-2016 IPR016496 GTPase HflX GO:0005525 A4G23_RS21270 a92cc96d031985796555a8c272c14eee 500 Gene3D G3DSA:3.40.50.300 278 441 6.8E-37 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS21270 a92cc96d031985796555a8c272c14eee 500 SUPERFAMILY SSF52540 280 463 2.6E-41 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS21270 a92cc96d031985796555a8c272c14eee 500 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 348 366 2.3E-6 T 10-11-2016 IPR006073 GTP binding domain GO:0005525 A4G23_RS21270 a92cc96d031985796555a8c272c14eee 500 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 281 301 2.3E-6 T 10-11-2016 IPR006073 GTP binding domain GO:0005525 A4G23_RS21270 a92cc96d031985796555a8c272c14eee 500 Pfam PF16360 GTP-binding GTPase Middle Region 190 273 9.7E-29 T 10-11-2016 IPR032305 GTP-binding protein, middle domain A4G23_RS21270 a92cc96d031985796555a8c272c14eee 500 Pfam PF13167 GTP-binding GTPase N-terminal 100 188 1.0E-31 T 10-11-2016 IPR025121 GTPase HflX, N-terminal A4G23_RS21270 a92cc96d031985796555a8c272c14eee 500 Hamap MF_00900 GTPase HflX [hflX]. 103 469 47.834 T 10-11-2016 IPR016496 GTPase HflX GO:0005525 A4G23_RS21270 a92cc96d031985796555a8c272c14eee 500 PIRSF PIRSF006809 48 498 1.1E-156 T 10-11-2016 IPR016496 GTPase HflX GO:0005525 A4G23_RS11265 981e5d11b7a7982629a8edae6a6e60cb 400 Gene3D G3DSA:1.10.630.10 12 400 2.8E-114 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS11265 981e5d11b7a7982629a8edae6a6e60cb 400 SUPERFAMILY SSF48264 14 400 8.38E-92 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS11265 981e5d11b7a7982629a8edae6a6e60cb 400 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 342 351 - T 10-11-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A4G23_RS11265 981e5d11b7a7982629a8edae6a6e60cb 400 PRINTS PR00385 P450 superfamily signature 349 360 2.9E-6 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS11265 981e5d11b7a7982629a8edae6a6e60cb 400 PRINTS PR00385 P450 superfamily signature 272 283 2.9E-6 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS11265 981e5d11b7a7982629a8edae6a6e60cb 400 PRINTS PR00385 P450 superfamily signature 237 254 2.9E-6 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS11265 981e5d11b7a7982629a8edae6a6e60cb 400 PRINTS PR00385 P450 superfamily signature 340 349 2.9E-6 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS11265 981e5d11b7a7982629a8edae6a6e60cb 400 Pfam PF00067 Cytochrome P450 174 373 7.3E-23 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS11265 981e5d11b7a7982629a8edae6a6e60cb 400 PRINTS PR00359 B-class P450 signature 192 214 1.3E-48 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS11265 981e5d11b7a7982629a8edae6a6e60cb 400 PRINTS PR00359 B-class P450 signature 154 169 1.3E-48 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS11265 981e5d11b7a7982629a8edae6a6e60cb 400 PRINTS PR00359 B-class P450 signature 340 349 1.3E-48 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS11265 981e5d11b7a7982629a8edae6a6e60cb 400 PRINTS PR00359 B-class P450 signature 319 334 1.3E-48 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS11265 981e5d11b7a7982629a8edae6a6e60cb 400 PRINTS PR00359 B-class P450 signature 272 283 1.3E-48 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS11265 981e5d11b7a7982629a8edae6a6e60cb 400 PRINTS PR00359 B-class P450 signature 137 153 1.3E-48 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS11265 981e5d11b7a7982629a8edae6a6e60cb 400 PRINTS PR00359 B-class P450 signature 90 101 1.3E-48 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS11265 981e5d11b7a7982629a8edae6a6e60cb 400 PRINTS PR00359 B-class P450 signature 291 318 1.3E-48 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS11265 981e5d11b7a7982629a8edae6a6e60cb 400 PRINTS PR00359 B-class P450 signature 349 360 1.3E-48 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS16080 f661b2ac32114725548a8685fc40c436 455 ProSitePatterns PS00667 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. 64 79 - T 10-11-2016 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16080 f661b2ac32114725548a8685fc40c436 455 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 18 355 23.892 T 10-11-2016 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16080 f661b2ac32114725548a8685fc40c436 455 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 231 244 - T 10-11-2016 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16080 f661b2ac32114725548a8685fc40c436 455 Pfam PF00146 NADH dehydrogenase 25 348 1.1E-120 T 10-11-2016 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS24080 951e202dccfe1ef9703ad79afe2d8bd6 397 SUPERFAMILY SSF141523 241 365 2.49E-24 T 10-11-2016 A4G23_RS24080 951e202dccfe1ef9703ad79afe2d8bd6 397 Pfam PF03734 L,D-transpeptidase catalytic domain 243 365 3.1E-13 T 10-11-2016 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 A4G23_RS24080 951e202dccfe1ef9703ad79afe2d8bd6 397 Gene3D G3DSA:2.40.440.10 241 365 3.3E-17 T 10-11-2016 A4G23_RS00025 2b5f86a7b28f5338b513e2da85ba44c3 1069 Pfam PF06527 TniQ 22 159 1.8E-6 T 10-11-2016 IPR009492 TniQ A4G23_RS00025 2b5f86a7b28f5338b513e2da85ba44c3 1069 Pfam PF03457 Helicase associated domain 379 437 1.4E-8 T 10-11-2016 IPR005114 Helicase-associated A4G23_RS00025 2b5f86a7b28f5338b513e2da85ba44c3 1069 Pfam PF03457 Helicase associated domain 523 585 8.4E-8 T 10-11-2016 IPR005114 Helicase-associated A4G23_RS00025 2b5f86a7b28f5338b513e2da85ba44c3 1069 Pfam PF03457 Helicase associated domain 953 1007 1.2E-8 T 10-11-2016 IPR005114 Helicase-associated A4G23_RS07965 a4ff146bbbd00ce1f77b6b69453bac0a 327 SUPERFAMILY SSF48019 203 321 4.25E-15 T 10-11-2016 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 A4G23_RS07965 a4ff146bbbd00ce1f77b6b69453bac0a 327 Pfam PF06144 DNA polymerase III, delta subunit 16 179 3.8E-13 T 10-11-2016 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 A4G23_RS07965 a4ff146bbbd00ce1f77b6b69453bac0a 327 Gene3D G3DSA:1.20.272.20 213 322 6.8E-4 T 10-11-2016 A4G23_RS07965 a4ff146bbbd00ce1f77b6b69453bac0a 327 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 11 319 4.9E-37 T 10-11-2016 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 A4G23_RS07965 a4ff146bbbd00ce1f77b6b69453bac0a 327 Gene3D G3DSA:1.10.8.60 137 212 7.2E-8 T 10-11-2016 A4G23_RS07965 a4ff146bbbd00ce1f77b6b69453bac0a 327 Gene3D G3DSA:3.40.50.300 9 107 3.7E-12 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS07965 a4ff146bbbd00ce1f77b6b69453bac0a 327 SUPERFAMILY SSF52540 9 184 3.72E-9 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS19045 47730567ff7ce76f1deae58f00672b5c 322 SUPERFAMILY SSF111331 1 322 2.49E-50 T 10-11-2016 IPR016064 NAD kinase/diacylglycerol kinase-like domain A4G23_RS19045 47730567ff7ce76f1deae58f00672b5c 322 Gene3D G3DSA:3.40.50.10330 7 77 1.1E-4 T 10-11-2016 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 A4G23_RS19045 47730567ff7ce76f1deae58f00672b5c 322 SMART SM00046 2 133 4.6E-11 T 10-11-2016 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 A4G23_RS19045 47730567ff7ce76f1deae58f00672b5c 322 Pfam PF00781 Diacylglycerol kinase catalytic domain 2 119 4.6E-27 T 10-11-2016 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 A4G23_RS25035 f84b1d7604069e567fc955ec38a5a6ca 711 Gene3D G3DSA:3.40.1110.10 278 378 2.6E-9 T 10-11-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A4G23_RS25035 f84b1d7604069e567fc955ec38a5a6ca 711 SUPERFAMILY SSF81665 163 248 2.22E-10 T 10-11-2016 A4G23_RS25035 f84b1d7604069e567fc955ec38a5a6ca 711 SUPERFAMILY SSF81665 23 66 2.22E-10 T 10-11-2016 A4G23_RS25035 f84b1d7604069e567fc955ec38a5a6ca 711 Gene3D G3DSA:1.20.120.520 573 709 6.0E-11 T 10-11-2016 A4G23_RS25035 f84b1d7604069e567fc955ec38a5a6ca 711 SUPERFAMILY SSF81653 65 161 6.93E-21 T 10-11-2016 A4G23_RS25035 f84b1d7604069e567fc955ec38a5a6ca 711 Gene3D G3DSA:2.70.150.10 18 162 7.7E-18 T 10-11-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 A4G23_RS25035 f84b1d7604069e567fc955ec38a5a6ca 711 Gene3D G3DSA:1.20.1110.10 199 277 3.2E-4 T 10-11-2016 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A4G23_RS25035 f84b1d7604069e567fc955ec38a5a6ca 711 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 12 554 1.8E-159 T 10-11-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A4G23_RS25035 f84b1d7604069e567fc955ec38a5a6ca 711 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 35 272 7.8E-29 T 10-11-2016 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A4G23_RS25035 f84b1d7604069e567fc955ec38a5a6ca 711 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 362 539 4.0E-31 T 10-11-2016 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A4G23_RS25035 f84b1d7604069e567fc955ec38a5a6ca 711 Pfam PF01814 Hemerythrin HHE cation binding domain 573 709 4.5E-18 T 10-11-2016 IPR012312 Haemerythrin-like Reactome: R-HSA-390471 A4G23_RS25035 f84b1d7604069e567fc955ec38a5a6ca 711 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 452 468 3.5E-5 T 10-11-2016 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A4G23_RS25035 f84b1d7604069e567fc955ec38a5a6ca 711 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 484 509 3.5E-5 T 10-11-2016 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A4G23_RS25035 f84b1d7604069e567fc955ec38a5a6ca 711 Pfam PF00702 haloacid dehalogenase-like hydrolase 251 466 1.5E-32 T 10-11-2016 A4G23_RS25035 f84b1d7604069e567fc955ec38a5a6ca 711 Pfam PF00122 E1-E2 ATPase 34 245 3.0E-51 T 10-11-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 A4G23_RS25035 f84b1d7604069e567fc955ec38a5a6ca 711 Gene3D G3DSA:3.40.50.1000 379 514 6.1E-33 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS25035 f84b1d7604069e567fc955ec38a5a6ca 711 SUPERFAMILY SSF56784 253 272 1.32E-40 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS25035 f84b1d7604069e567fc955ec38a5a6ca 711 SUPERFAMILY SSF56784 311 553 1.32E-40 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS25035 f84b1d7604069e567fc955ec38a5a6ca 711 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 256 262 - T 10-11-2016 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 A4G23_RS25035 f84b1d7604069e567fc955ec38a5a6ca 711 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 377 388 2.3E-25 T 10-11-2016 A4G23_RS25035 f84b1d7604069e567fc955ec38a5a6ca 711 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 452 471 2.3E-25 T 10-11-2016 A4G23_RS25035 f84b1d7604069e567fc955ec38a5a6ca 711 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 254 268 2.3E-25 T 10-11-2016 A4G23_RS25035 f84b1d7604069e567fc955ec38a5a6ca 711 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 400 410 2.3E-25 T 10-11-2016 A4G23_RS25035 f84b1d7604069e567fc955ec38a5a6ca 711 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 476 488 2.3E-25 T 10-11-2016 A4G23_RS25035 f84b1d7604069e567fc955ec38a5a6ca 711 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 112 126 2.3E-25 T 10-11-2016 A4G23_RS10395 983b201c0607579efb36a8a58b648db1 330 Pfam PF06737 Transglycosylase-like domain 18 94 3.6E-31 T 10-11-2016 IPR010618 Transglycosylase-like A4G23_RS10395 983b201c0607579efb36a8a58b648db1 330 Gene3D G3DSA:1.10.530.10 2 100 6.5E-38 T 10-11-2016 A4G23_RS10395 983b201c0607579efb36a8a58b648db1 330 SUPERFAMILY SSF54106 277 325 2.35E-6 T 10-11-2016 IPR018392 LysM domain A4G23_RS10395 983b201c0607579efb36a8a58b648db1 330 Gene3D G3DSA:3.10.350.10 277 325 1.1E-9 T 10-11-2016 IPR018392 LysM domain A4G23_RS10395 983b201c0607579efb36a8a58b648db1 330 Pfam PF01476 LysM domain 278 323 1.3E-6 T 10-11-2016 IPR018392 LysM domain A4G23_RS10395 983b201c0607579efb36a8a58b648db1 330 SUPERFAMILY SSF53955 19 100 5.25E-28 T 10-11-2016 IPR023346 Lysozyme-like domain A4G23_RS10395 983b201c0607579efb36a8a58b648db1 330 SMART SM00257 277 326 2.9E-7 T 10-11-2016 IPR018392 LysM domain A4G23_RS20265 9091f3ef1978dc123d4db6b58de3cd64 1328 Gene3D G3DSA:3.30.565.10 603 744 7.6E-16 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS20265 9091f3ef1978dc123d4db6b58de3cd64 1328 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 636 742 2.4E-10 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS20265 9091f3ef1978dc123d4db6b58de3cd64 1328 SUPERFAMILY SSF55874 623 741 8.77E-19 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS20265 9091f3ef1978dc123d4db6b58de3cd64 1328 Pfam PF08376 Nitrate and nitrite sensing 161 413 2.6E-34 T 10-11-2016 IPR013587 Nitrate/nitrite sensing protein A4G23_RS20265 9091f3ef1978dc123d4db6b58de3cd64 1328 Pfam PF00672 HAMP domain 433 517 6.7E-17 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS20265 9091f3ef1978dc123d4db6b58de3cd64 1328 SMART SM00304 451 521 6.0E-5 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS11540 4776713f5135c55dcaef582f2de6dc37 263 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 8 225 9.8E-47 T 10-11-2016 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type A4G23_RS11540 4776713f5135c55dcaef582f2de6dc37 263 Gene3D G3DSA:1.20.120.450 5 130 5.2E-6 T 10-11-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase A4G23_RS11540 4776713f5135c55dcaef582f2de6dc37 263 SUPERFAMILY SSF109854 3 153 1.63E-33 T 10-11-2016 A4G23_RS11540 4776713f5135c55dcaef582f2de6dc37 263 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 9 148 2.7E-30 T 10-11-2016 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 A4G23_RS11540 4776713f5135c55dcaef582f2de6dc37 263 TIGRFAM TIGR03084 TIGR03084: TIGR03084 family protein 5 258 2.5E-105 T 10-11-2016 IPR017518 Conserved hypothetical protein CHP03084 A4G23_RS24750 9c02c35222b0368704a078b5fc79de9f 726 SUPERFAMILY SSF51735 322 504 3.72E-55 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS24750 9c02c35222b0368704a078b5fc79de9f 726 SUPERFAMILY SSF48179 505 647 1.45E-14 T 10-11-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A4G23_RS24750 9c02c35222b0368704a078b5fc79de9f 726 SUPERFAMILY SSF48179 633 724 1.53E-17 T 10-11-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A4G23_RS24750 9c02c35222b0368704a078b5fc79de9f 726 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 506 606 2.0E-17 T 10-11-2016 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 A4G23_RS24750 9c02c35222b0368704a078b5fc79de9f 726 Gene3D G3DSA:1.10.1040.10 646 724 5.2E-9 T 10-11-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A4G23_RS24750 9c02c35222b0368704a078b5fc79de9f 726 SUPERFAMILY SSF52096 6 305 1.23E-58 T 10-11-2016 IPR029045 ClpP/crotonase-like domain A4G23_RS24750 9c02c35222b0368704a078b5fc79de9f 726 Pfam PF00378 Enoyl-CoA hydratase/isomerase 16 209 3.8E-30 T 10-11-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 A4G23_RS24750 9c02c35222b0368704a078b5fc79de9f 726 Gene3D G3DSA:1.10.1040.10 508 607 1.7E-9 T 10-11-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A4G23_RS24750 9c02c35222b0368704a078b5fc79de9f 726 Gene3D G3DSA:3.40.50.720 316 507 4.8E-58 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS24750 9c02c35222b0368704a078b5fc79de9f 726 Gene3D G3DSA:3.90.226.10 243 302 7.8E-54 T 10-11-2016 IPR029045 ClpP/crotonase-like domain A4G23_RS24750 9c02c35222b0368704a078b5fc79de9f 726 Gene3D G3DSA:3.90.226.10 6 209 7.8E-54 T 10-11-2016 IPR029045 ClpP/crotonase-like domain A4G23_RS24750 9c02c35222b0368704a078b5fc79de9f 726 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 326 503 5.0E-63 T 10-11-2016 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 A4G23_RS23750 3236e032ed310bf9c4302f184113db77 573 Gene3D G3DSA:3.30.70.20 203 242 2.5E-24 T 10-11-2016 A4G23_RS23750 3236e032ed310bf9c4302f184113db77 573 TIGRFAM TIGR01660 narH: nitrate reductase, beta subunit 11 494 1.6E-226 T 10-11-2016 IPR006547 Nitrate reductase, beta subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.99.4 A4G23_RS23750 3236e032ed310bf9c4302f184113db77 573 Gene3D G3DSA:3.30.70.20 181 202 7.6E-11 T 10-11-2016 A4G23_RS23750 3236e032ed310bf9c4302f184113db77 573 Gene3D G3DSA:3.30.70.20 18 34 7.6E-11 T 10-11-2016 A4G23_RS23750 3236e032ed310bf9c4302f184113db77 573 Gene3D G3DSA:3.30.70.20 133 134 7.6E-11 T 10-11-2016 A4G23_RS23750 3236e032ed310bf9c4302f184113db77 573 Gene3D G3DSA:3.30.70.20 446 475 5.0E-68 T 10-11-2016 A4G23_RS23750 3236e032ed310bf9c4302f184113db77 573 Gene3D G3DSA:3.30.70.20 243 365 5.0E-68 T 10-11-2016 A4G23_RS23750 3236e032ed310bf9c4302f184113db77 573 Pfam PF14711 Respiratory nitrate reductase beta C-terminal 365 446 3.8E-28 T 10-11-2016 IPR029263 Respiratory nitrate reductase beta, C-terminal KEGG: 00910+1.7.99.4 A4G23_RS23750 3236e032ed310bf9c4302f184113db77 573 SUPERFAMILY SSF54862 11 495 3.24E-158 T 10-11-2016 A4G23_RS23750 3236e032ed310bf9c4302f184113db77 573 Gene3D G3DSA:1.10.3650.10 366 444 2.6E-27 T 10-11-2016 IPR029263 Respiratory nitrate reductase beta, C-terminal KEGG: 00910+1.7.99.4 A4G23_RS23750 3236e032ed310bf9c4302f184113db77 573 Pfam PF13247 4Fe-4S dicluster domain 182 277 7.7E-37 T 10-11-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4G23_RS22760 53ea5b0c8efc6f3c5ebf8cdb575767cd 333 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 53 60 - T 10-11-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A4G23_RS22760 53ea5b0c8efc6f3c5ebf8cdb575767cd 333 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 158 329 2.4E-51 T 10-11-2016 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 A4G23_RS22760 53ea5b0c8efc6f3c5ebf8cdb575767cd 333 Gene3D G3DSA:3.40.50.1370 145 318 7.0E-69 T 10-11-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A4G23_RS22760 53ea5b0c8efc6f3c5ebf8cdb575767cd 333 SUPERFAMILY SSF53671 4 331 4.32E-95 T 10-11-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A4G23_RS22760 53ea5b0c8efc6f3c5ebf8cdb575767cd 333 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 7.4E-26 T 10-11-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A4G23_RS22760 53ea5b0c8efc6f3c5ebf8cdb575767cd 333 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 296 319 7.4E-26 T 10-11-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A4G23_RS22760 53ea5b0c8efc6f3c5ebf8cdb575767cd 333 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 53 72 7.4E-26 T 10-11-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A4G23_RS22760 53ea5b0c8efc6f3c5ebf8cdb575767cd 333 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 267 276 7.4E-26 T 10-11-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A4G23_RS22760 53ea5b0c8efc6f3c5ebf8cdb575767cd 333 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 7 332 82.248 T 10-11-2016 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 A4G23_RS22760 53ea5b0c8efc6f3c5ebf8cdb575767cd 333 Gene3D G3DSA:3.40.50.1370 5 144 3.8E-54 T 10-11-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A4G23_RS22760 53ea5b0c8efc6f3c5ebf8cdb575767cd 333 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 8 148 8.8E-45 T 10-11-2016 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 A4G23_RS22760 53ea5b0c8efc6f3c5ebf8cdb575767cd 333 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 8 331 3.3E-123 T 10-11-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4G23_RS22760 53ea5b0c8efc6f3c5ebf8cdb575767cd 333 PRINTS PR00102 Ornithine carbamoyltransferase signature 229 239 5.7E-31 T 10-11-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4G23_RS22760 53ea5b0c8efc6f3c5ebf8cdb575767cd 333 PRINTS PR00102 Ornithine carbamoyltransferase signature 51 65 5.7E-31 T 10-11-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4G23_RS22760 53ea5b0c8efc6f3c5ebf8cdb575767cd 333 PRINTS PR00102 Ornithine carbamoyltransferase signature 310 321 5.7E-31 T 10-11-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4G23_RS22760 53ea5b0c8efc6f3c5ebf8cdb575767cd 333 PRINTS PR00102 Ornithine carbamoyltransferase signature 124 138 5.7E-31 T 10-11-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4G23_RS22760 53ea5b0c8efc6f3c5ebf8cdb575767cd 333 PRINTS PR00102 Ornithine carbamoyltransferase signature 84 97 5.7E-31 T 10-11-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4G23_RS25895 53a450017dc75bc2c8031c859b5586a1 415 SUPERFAMILY SSF55931 289 412 2.45E-34 T 10-11-2016 A4G23_RS25895 53a450017dc75bc2c8031c859b5586a1 415 SUPERFAMILY SSF55931 27 253 2.45E-34 T 10-11-2016 A4G23_RS25895 53a450017dc75bc2c8031c859b5586a1 415 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 35 338 1.6E-72 T 10-11-2016 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 A4G23_RS25895 53a450017dc75bc2c8031c859b5586a1 415 Hamap MF_02034 Glutamate--cysteine ligase EgtA [egtA]. 10 412 29.449 T 10-11-2016 IPR017809 Glutamate--cysteine ligase EgtA, Actinobacteria GO:0004357|GO:0052699 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 A4G23_RS25895 53a450017dc75bc2c8031c859b5586a1 415 TIGRFAM TIGR03444 EgtA_Cys_ligase: ergothioneine biosynthesis glutamate--cysteine ligase EgtA 23 414 2.9E-124 T 10-11-2016 IPR017809 Glutamate--cysteine ligase EgtA, Actinobacteria GO:0004357|GO:0052699 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 A4G23_RS25895 53a450017dc75bc2c8031c859b5586a1 415 PIRSF PIRSF017901 14 415 3.8E-101 T 10-11-2016 A4G23_RS20420 fea24139da42e3c395ab2cf1c14e5669 286 SUPERFAMILY SSF54768 130 242 8.17E-27 T 10-11-2016 A4G23_RS20420 fea24139da42e3c395ab2cf1c14e5669 286 SMART SM00358 176 242 1.9E-24 T 10-11-2016 IPR014720 Double-stranded RNA-binding domain A4G23_RS20420 fea24139da42e3c395ab2cf1c14e5669 286 Pfam PF00035 Double-stranded RNA binding motif 176 239 5.1E-17 T 10-11-2016 IPR014720 Double-stranded RNA-binding domain A4G23_RS20420 fea24139da42e3c395ab2cf1c14e5669 286 ProSitePatterns PS00517 Ribonuclease III family signature. 58 66 - T 10-11-2016 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 A4G23_RS20420 fea24139da42e3c395ab2cf1c14e5669 286 SUPERFAMILY SSF69065 20 178 1.92E-49 T 10-11-2016 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 A4G23_RS20420 fea24139da42e3c395ab2cf1c14e5669 286 Gene3D G3DSA:3.30.160.20 174 241 1.9E-26 T 10-11-2016 IPR014720 Double-stranded RNA-binding domain A4G23_RS20420 fea24139da42e3c395ab2cf1c14e5669 286 SMART SM00535 36 169 6.7E-62 T 10-11-2016 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 A4G23_RS20420 fea24139da42e3c395ab2cf1c14e5669 286 Hamap MF_00104 Ribonuclease 3 [rnc]. 25 238 30.742 T 10-11-2016 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 A4G23_RS20420 fea24139da42e3c395ab2cf1c14e5669 286 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 28 240 3.0E-73 T 10-11-2016 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 A4G23_RS20420 fea24139da42e3c395ab2cf1c14e5669 286 Pfam PF14622 Ribonuclease-III-like 35 160 2.1E-38 T 10-11-2016 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 A4G23_RS20420 fea24139da42e3c395ab2cf1c14e5669 286 Gene3D G3DSA:1.10.1520.10 25 166 4.7E-47 T 10-11-2016 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 A4G23_RS23615 f198fbb384c13ad9b2d45fbc1653b707 657 Gene3D G3DSA:3.20.20.140 355 408 7.0E-39 T 10-11-2016 A4G23_RS23615 f198fbb384c13ad9b2d45fbc1653b707 657 Gene3D G3DSA:3.20.20.140 122 295 7.0E-39 T 10-11-2016 A4G23_RS23615 f198fbb384c13ad9b2d45fbc1653b707 657 SUPERFAMILY SSF51556 124 289 9.36E-29 T 10-11-2016 IPR032466 Metal-dependent hydrolase A4G23_RS23615 f198fbb384c13ad9b2d45fbc1653b707 657 SUPERFAMILY SSF51556 344 465 9.36E-29 T 10-11-2016 IPR032466 Metal-dependent hydrolase A4G23_RS23615 f198fbb384c13ad9b2d45fbc1653b707 657 Gene3D G3DSA:2.60.120.260 538 654 4.1E-20 T 10-11-2016 IPR008979 Galactose-binding domain-like A4G23_RS23615 f198fbb384c13ad9b2d45fbc1653b707 657 Pfam PF00754 F5/8 type C domain 543 649 5.2E-21 T 10-11-2016 IPR000421 Coagulation factor 5/8 C-terminal domain A4G23_RS23615 f198fbb384c13ad9b2d45fbc1653b707 657 SUPERFAMILY SSF49785 531 654 4.54E-21 T 10-11-2016 IPR008979 Galactose-binding domain-like A4G23_RS23620 6b72a890a3c6cc7e154c1ce2eb155b72 778 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 185 432 7.0E-62 T 10-11-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A4G23_RS23620 6b72a890a3c6cc7e154c1ce2eb155b72 778 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 30 438 1.6E-111 T 10-11-2016 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 A4G23_RS23620 6b72a890a3c6cc7e154c1ce2eb155b72 778 SUPERFAMILY SSF82866 245 441 1.26E-33 T 10-11-2016 A4G23_RS23620 6b72a890a3c6cc7e154c1ce2eb155b72 778 Pfam PF02355 Protein export membrane protein 269 439 9.0E-15 T 10-11-2016 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial A4G23_RS23620 6b72a890a3c6cc7e154c1ce2eb155b72 778 Pfam PF02355 Protein export membrane protein 574 752 4.9E-59 T 10-11-2016 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial A4G23_RS23620 6b72a890a3c6cc7e154c1ce2eb155b72 778 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 500 741 1.1E-59 T 10-11-2016 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 A4G23_RS23620 6b72a890a3c6cc7e154c1ce2eb155b72 778 PRINTS PR01755 Bacterial translocase SecF protein signature 499 514 8.5E-21 T 10-11-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A4G23_RS23620 6b72a890a3c6cc7e154c1ce2eb155b72 778 PRINTS PR01755 Bacterial translocase SecF protein signature 609 623 8.5E-21 T 10-11-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A4G23_RS23620 6b72a890a3c6cc7e154c1ce2eb155b72 778 PRINTS PR01755 Bacterial translocase SecF protein signature 657 675 8.5E-21 T 10-11-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A4G23_RS23620 6b72a890a3c6cc7e154c1ce2eb155b72 778 PRINTS PR01755 Bacterial translocase SecF protein signature 691 706 8.5E-21 T 10-11-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A4G23_RS23620 6b72a890a3c6cc7e154c1ce2eb155b72 778 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 2 454 36.391 T 10-11-2016 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 A4G23_RS23620 6b72a890a3c6cc7e154c1ce2eb155b72 778 Pfam PF07549 SecD/SecF GG Motif 496 521 2.1E-6 T 10-11-2016 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site A4G23_RS23620 6b72a890a3c6cc7e154c1ce2eb155b72 778 Pfam PF07549 SecD/SecF GG Motif 25 44 2.5E-4 T 10-11-2016 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site A4G23_RS23620 6b72a890a3c6cc7e154c1ce2eb155b72 778 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 472 754 25.941 T 10-11-2016 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 A4G23_RS23620 6b72a890a3c6cc7e154c1ce2eb155b72 778 Gene3D G3DSA:1.20.1640.10 258 451 1.7E-23 T 10-11-2016 A4G23_RS23620 6b72a890a3c6cc7e154c1ce2eb155b72 778 Gene3D G3DSA:1.20.1640.10 585 758 2.2E-20 T 10-11-2016 A4G23_RS23620 6b72a890a3c6cc7e154c1ce2eb155b72 778 SUPERFAMILY SSF82866 583 752 2.22E-30 T 10-11-2016 A4G23_RS14960 d43a1b9c305b9b508c414b9bf6e31826 507 Pfam PF05175 Methyltransferase small domain 163 280 2.1E-13 T 10-11-2016 IPR007848 Methyltransferase small domain GO:0008168 A4G23_RS14960 d43a1b9c305b9b508c414b9bf6e31826 507 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 231 237 - T 10-11-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A4G23_RS14960 d43a1b9c305b9b508c414b9bf6e31826 507 SUPERFAMILY SSF53335 162 305 1.49E-23 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS14960 d43a1b9c305b9b508c414b9bf6e31826 507 Gene3D G3DSA:3.40.50.150 151 307 5.2E-27 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS26900 811ee72658b320f606a3485d14f0d8b1 222 SUPERFAMILY SSF56784 1 213 1.33E-46 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS26900 811ee72658b320f606a3485d14f0d8b1 222 Gene3D G3DSA:3.40.50.1000 87 214 3.1E-31 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS26900 811ee72658b320f606a3485d14f0d8b1 222 Gene3D G3DSA:3.40.50.1000 2 16 3.1E-31 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS26900 811ee72658b320f606a3485d14f0d8b1 222 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 182 3.6E-25 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS26900 811ee72658b320f606a3485d14f0d8b1 222 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 75 182 1.6E-7 T 10-11-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A4G23_RS16740 e161526f4c7ee6032b6da6d260415600 340 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 24 218 2.4E-19 T 10-11-2016 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4G23_RS16740 e161526f4c7ee6032b6da6d260415600 340 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 57 149 5.7E-24 T 10-11-2016 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4G23_RS16740 e161526f4c7ee6032b6da6d260415600 340 Gene3D G3DSA:1.10.150.20 245 319 9.2E-32 T 10-11-2016 A4G23_RS16740 e161526f4c7ee6032b6da6d260415600 340 SUPERFAMILY SSF55257 14 48 2.35E-24 T 10-11-2016 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4G23_RS16740 e161526f4c7ee6032b6da6d260415600 340 SUPERFAMILY SSF55257 170 220 2.35E-24 T 10-11-2016 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4G23_RS16740 e161526f4c7ee6032b6da6d260415600 340 Gene3D G3DSA:3.30.1360.10 171 217 2.2E-4 T 10-11-2016 A4G23_RS16740 e161526f4c7ee6032b6da6d260415600 340 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 19 310 2.1E-115 T 10-11-2016 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4G23_RS16740 e161526f4c7ee6032b6da6d260415600 340 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 257 311 2.0E-24 T 10-11-2016 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4G23_RS16740 e161526f4c7ee6032b6da6d260415600 340 Gene3D G3DSA:3.30.1360.10 7 61 1.3E-10 T 10-11-2016 A4G23_RS16740 e161526f4c7ee6032b6da6d260415600 340 SUPERFAMILY SSF47789 247 318 1.83E-23 T 10-11-2016 A4G23_RS16740 e161526f4c7ee6032b6da6d260415600 340 SUPERFAMILY SSF56553 48 169 6.28E-42 T 10-11-2016 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4G23_RS16740 e161526f4c7ee6032b6da6d260415600 340 Gene3D G3DSA:2.170.120.12 62 168 2.2E-45 T 10-11-2016 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4G23_RS16740 e161526f4c7ee6032b6da6d260415600 340 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 245 302 5.9E-26 T 10-11-2016 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4G23_RS16740 e161526f4c7ee6032b6da6d260415600 340 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 1 311 34.296 T 10-11-2016 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4G23_RS16740 e161526f4c7ee6032b6da6d260415600 340 SMART SM00662 18 225 1.0E-94 T 10-11-2016 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4G23_RS10880 ef3169ad5ee7fae7b9fb243f21dda50a 419 SUPERFAMILY SSF53218 184 338 5.37E-38 T 10-11-2016 IPR001453 MoaB/Mog domain A4G23_RS10880 ef3169ad5ee7fae7b9fb243f21dda50a 419 Gene3D G3DSA:2.170.190.11 34 138 2.2E-32 T 10-11-2016 A4G23_RS10880 ef3169ad5ee7fae7b9fb243f21dda50a 419 Pfam PF03454 MoeA C-terminal region (domain IV) 352 417 3.5E-16 T 10-11-2016 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4G23_RS10880 ef3169ad5ee7fae7b9fb243f21dda50a 419 Gene3D G3DSA:3.40.980.10 170 347 1.9E-59 T 10-11-2016 IPR001453 MoaB/Mog domain A4G23_RS10880 ef3169ad5ee7fae7b9fb243f21dda50a 419 Gene3D G3DSA:3.90.105.10 139 169 1.0E-19 T 10-11-2016 A4G23_RS10880 ef3169ad5ee7fae7b9fb243f21dda50a 419 Pfam PF00994 Probable molybdopterin binding domain 189 333 1.3E-28 T 10-11-2016 IPR001453 MoaB/Mog domain A4G23_RS10880 ef3169ad5ee7fae7b9fb243f21dda50a 419 SUPERFAMILY SSF63867 344 418 2.22E-15 T 10-11-2016 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4G23_RS10880 ef3169ad5ee7fae7b9fb243f21dda50a 419 Gene3D G3DSA:2.40.340.10 348 418 2.4E-18 T 10-11-2016 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4G23_RS10880 ef3169ad5ee7fae7b9fb243f21dda50a 419 SUPERFAMILY SSF63882 2 184 1.44E-46 T 10-11-2016 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4G23_RS10880 ef3169ad5ee7fae7b9fb243f21dda50a 419 SMART SM00852 188 334 2.2E-41 T 10-11-2016 IPR001453 MoaB/Mog domain A4G23_RS10880 ef3169ad5ee7fae7b9fb243f21dda50a 419 Pfam PF03453 MoeA N-terminal region (domain I and II) 12 175 1.4E-33 T 10-11-2016 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4G23_RS10880 ef3169ad5ee7fae7b9fb243f21dda50a 419 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 185 330 9.1E-32 T 10-11-2016 IPR001453 MoaB/Mog domain A4G23_RS07915 a5c25c43f048e42ed1bb46dd386f5bef 247 Gene3D G3DSA:3.40.1280.10 4 246 5.7E-69 T 10-11-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A4G23_RS07915 a5c25c43f048e42ed1bb46dd386f5bef 247 Pfam PF04452 RNA methyltransferase 21 239 8.4E-60 T 10-11-2016 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A4G23_RS07915 a5c25c43f048e42ed1bb46dd386f5bef 247 SUPERFAMILY SSF75217 78 246 9.42E-45 T 10-11-2016 IPR029028 Alpha/beta knot methyltransferases A4G23_RS07915 a5c25c43f048e42ed1bb46dd386f5bef 247 SUPERFAMILY SSF88697 5 72 1.09E-10 T 10-11-2016 IPR015947 PUA-like domain A4G23_RS07915 a5c25c43f048e42ed1bb46dd386f5bef 247 PIRSF PIRSF015601 2 246 1.5E-44 T 10-11-2016 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A4G23_RS07915 a5c25c43f048e42ed1bb46dd386f5bef 247 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 20 239 2.4E-31 T 10-11-2016 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A4G23_RS16350 32995145287ea35187e70af92942dae1 240 Pfam PF00687 Ribosomal protein L1p/L10e family 31 219 8.6E-53 T 10-11-2016 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein A4G23_RS16350 32995145287ea35187e70af92942dae1 240 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 2 226 1.2E-101 T 10-11-2016 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 A4G23_RS16350 32995145287ea35187e70af92942dae1 240 PIRSF PIRSF002155 1 226 3.0E-72 T 10-11-2016 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS16350 32995145287ea35187e70af92942dae1 240 Gene3D G3DSA:3.30.190.20 16 67 3.2E-45 T 10-11-2016 IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich GO:0003723 A4G23_RS16350 32995145287ea35187e70af92942dae1 240 Gene3D G3DSA:3.30.190.20 160 225 3.2E-45 T 10-11-2016 IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich GO:0003723 A4G23_RS16350 32995145287ea35187e70af92942dae1 240 SUPERFAMILY SSF56808 9 225 9.55E-82 T 10-11-2016 IPR023674 Ribosomal protein L1-like A4G23_RS16350 32995145287ea35187e70af92942dae1 240 Gene3D G3DSA:3.40.50.790 68 158 3.6E-41 T 10-11-2016 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich A4G23_RS16350 32995145287ea35187e70af92942dae1 240 ProSitePatterns PS01199 Ribosomal protein L1 signature. 120 138 - T 10-11-2016 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS16350 32995145287ea35187e70af92942dae1 240 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 1 228 42.664 T 10-11-2016 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 A4G23_RS05675 8b7faad332e136a0924581280af65062 403 SUPERFAMILY SSF53748 8 403 1.77E-141 T 10-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4G23_RS05675 8b7faad332e136a0924581280af65062 403 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 16 26 - T 10-11-2016 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4G23_RS05675 8b7faad332e136a0924581280af65062 403 PRINTS PR00477 Phosphoglycerate kinase family signature 355 366 2.2E-80 T 10-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4G23_RS05675 8b7faad332e136a0924581280af65062 403 PRINTS PR00477 Phosphoglycerate kinase family signature 142 164 2.2E-80 T 10-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4G23_RS05675 8b7faad332e136a0924581280af65062 403 PRINTS PR00477 Phosphoglycerate kinase family signature 11 27 2.2E-80 T 10-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4G23_RS05675 8b7faad332e136a0924581280af65062 403 PRINTS PR00477 Phosphoglycerate kinase family signature 195 214 2.2E-80 T 10-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4G23_RS05675 8b7faad332e136a0924581280af65062 403 PRINTS PR00477 Phosphoglycerate kinase family signature 32 54 2.2E-80 T 10-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4G23_RS05675 8b7faad332e136a0924581280af65062 403 PRINTS PR00477 Phosphoglycerate kinase family signature 322 347 2.2E-80 T 10-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4G23_RS05675 8b7faad332e136a0924581280af65062 403 PRINTS PR00477 Phosphoglycerate kinase family signature 110 125 2.2E-80 T 10-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4G23_RS05675 8b7faad332e136a0924581280af65062 403 PRINTS PR00477 Phosphoglycerate kinase family signature 379 396 2.2E-80 T 10-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4G23_RS05675 8b7faad332e136a0924581280af65062 403 PRINTS PR00477 Phosphoglycerate kinase family signature 172 194 2.2E-80 T 10-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4G23_RS05675 8b7faad332e136a0924581280af65062 403 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 3 403 40.801 T 10-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4G23_RS05675 8b7faad332e136a0924581280af65062 403 PIRSF PIRSF000724 1 403 2.1E-132 T 10-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4G23_RS05675 8b7faad332e136a0924581280af65062 403 Gene3D G3DSA:3.40.50.1260 10 184 7.8E-64 T 10-11-2016 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4G23_RS05675 8b7faad332e136a0924581280af65062 403 Gene3D G3DSA:3.40.50.1270 185 391 2.5E-78 T 10-11-2016 IPR015901 Phosphoglycerate kinase, C-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4G23_RS05675 8b7faad332e136a0924581280af65062 403 Pfam PF00162 Phosphoglycerate kinase 12 393 3.5E-145 T 10-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4G23_RS04825 aabb7bf49982cf187fb6850bc90f6f48 194 Pfam PF01476 LysM domain 146 193 5.1E-6 T 10-11-2016 IPR018392 LysM domain A4G23_RS04825 aabb7bf49982cf187fb6850bc90f6f48 194 SUPERFAMILY SSF53955 62 141 1.76E-30 T 10-11-2016 IPR023346 Lysozyme-like domain A4G23_RS04825 aabb7bf49982cf187fb6850bc90f6f48 194 SUPERFAMILY SSF54106 145 194 6.41E-6 T 10-11-2016 IPR018392 LysM domain A4G23_RS04825 aabb7bf49982cf187fb6850bc90f6f48 194 SMART SM00257 145 194 5.2E-6 T 10-11-2016 IPR018392 LysM domain A4G23_RS04825 aabb7bf49982cf187fb6850bc90f6f48 194 Gene3D G3DSA:1.10.530.10 39 141 2.3E-36 T 10-11-2016 A4G23_RS04825 aabb7bf49982cf187fb6850bc90f6f48 194 Pfam PF06737 Transglycosylase-like domain 65 135 3.4E-30 T 10-11-2016 IPR010618 Transglycosylase-like A4G23_RS04825 aabb7bf49982cf187fb6850bc90f6f48 194 Gene3D G3DSA:3.10.350.10 145 194 4.3E-9 T 10-11-2016 IPR018392 LysM domain A4G23_RS26305 5d5fe5b47344d7b0570695bb3c294749 2564 SUPERFAMILY SSF47336 2201 2271 3.89E-16 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS26305 5d5fe5b47344d7b0570695bb3c294749 2564 SUPERFAMILY SSF53474 2295 2557 1.84E-45 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS26305 5d5fe5b47344d7b0570695bb3c294749 2564 Gene3D G3DSA:3.40.50.980 775 942 4.2E-43 T 10-11-2016 A4G23_RS26305 5d5fe5b47344d7b0570695bb3c294749 2564 SUPERFAMILY SSF52777 282 544 2.22E-54 T 10-11-2016 A4G23_RS26305 5d5fe5b47344d7b0570695bb3c294749 2564 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2233 2248 - T 10-11-2016 IPR006162 Phosphopantetheine attachment site A4G23_RS26305 5d5fe5b47344d7b0570695bb3c294749 2564 Pfam PF00975 Thioesterase domain 2305 2546 1.6E-20 T 10-11-2016 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 A4G23_RS26305 5d5fe5b47344d7b0570695bb3c294749 2564 SMART SM00823 Phosphopantetheine attachment site 1139 1207 0.0032 T 10-11-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4G23_RS26305 5d5fe5b47344d7b0570695bb3c294749 2564 SMART SM00823 Phosphopantetheine attachment site 2209 2277 0.089 T 10-11-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4G23_RS26305 5d5fe5b47344d7b0570695bb3c294749 2564 Gene3D G3DSA:3.40.50.980 580 693 1.8E-42 T 10-11-2016 A4G23_RS26305 5d5fe5b47344d7b0570695bb3c294749 2564 Gene3D G3DSA:3.40.50.980 1704 1871 5.8E-45 T 10-11-2016 A4G23_RS26305 5d5fe5b47344d7b0570695bb3c294749 2564 Gene3D G3DSA:3.40.50.980 750 774 1.8E-42 T 10-11-2016 A4G23_RS26305 5d5fe5b47344d7b0570695bb3c294749 2564 Pfam PF00501 AMP-binding enzyme 1711 2097 3.1E-89 T 10-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A4G23_RS26305 5d5fe5b47344d7b0570695bb3c294749 2564 Pfam PF00501 AMP-binding enzyme 586 1030 3.7E-93 T 10-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A4G23_RS26305 5d5fe5b47344d7b0570695bb3c294749 2564 SUPERFAMILY SSF52777 1229 1435 1.1E-32 T 10-11-2016 A4G23_RS26305 5d5fe5b47344d7b0570695bb3c294749 2564 Gene3D G3DSA:2.30.38.10 2010 2085 1.1E-25 T 10-11-2016 A4G23_RS26305 5d5fe5b47344d7b0570695bb3c294749 2564 Gene3D G3DSA:2.30.38.10 943 1020 2.9E-24 T 10-11-2016 A4G23_RS26305 5d5fe5b47344d7b0570695bb3c294749 2564 Gene3D G3DSA:3.40.50.980 1872 2009 2.1E-36 T 10-11-2016 A4G23_RS26305 5d5fe5b47344d7b0570695bb3c294749 2564 Gene3D G3DSA:3.30.300.30 2093 2212 2.1E-39 T 10-11-2016 A4G23_RS26305 5d5fe5b47344d7b0570695bb3c294749 2564 Gene3D G3DSA:3.30.300.30 1025 1142 1.9E-41 T 10-11-2016 A4G23_RS26305 5d5fe5b47344d7b0570695bb3c294749 2564 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1730 2121 2.2E-122 T 10-11-2016 IPR010071 Amino acid adenylation domain A4G23_RS26305 5d5fe5b47344d7b0570695bb3c294749 2564 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 607 1054 1.5E-129 T 10-11-2016 IPR010071 Amino acid adenylation domain A4G23_RS26305 5d5fe5b47344d7b0570695bb3c294749 2564 Pfam PF00668 Condensation domain 99 393 2.6E-69 T 10-11-2016 IPR001242 Condensation domain A4G23_RS26305 5d5fe5b47344d7b0570695bb3c294749 2564 Pfam PF00668 Condensation domain 1233 1557 2.8E-28 T 10-11-2016 IPR001242 Condensation domain A4G23_RS26305 5d5fe5b47344d7b0570695bb3c294749 2564 ProSitePatterns PS00455 Putative AMP-binding domain signature. 765 776 - T 10-11-2016 IPR020845 AMP-binding, conserved site A4G23_RS26305 5d5fe5b47344d7b0570695bb3c294749 2564 Pfam PF00550 Phosphopantetheine attachment site 1141 1202 9.7E-10 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS26305 5d5fe5b47344d7b0570695bb3c294749 2564 Pfam PF00550 Phosphopantetheine attachment site 2212 2272 2.1E-10 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS26305 5d5fe5b47344d7b0570695bb3c294749 2564 SUPERFAMILY SSF56801 539 1152 4.06E-151 T 10-11-2016 A4G23_RS26305 5d5fe5b47344d7b0570695bb3c294749 2564 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1163 1178 - T 10-11-2016 IPR006162 Phosphopantetheine attachment site A4G23_RS26305 5d5fe5b47344d7b0570695bb3c294749 2564 SUPERFAMILY SSF47336 1131 1201 1.34E-16 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS26305 5d5fe5b47344d7b0570695bb3c294749 2564 SUPERFAMILY SSF52777 1423 1673 3.78E-29 T 10-11-2016 A4G23_RS26305 5d5fe5b47344d7b0570695bb3c294749 2564 Gene3D G3DSA:3.40.50.1820 2481 2554 1.1E-36 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS26305 5d5fe5b47344d7b0570695bb3c294749 2564 Gene3D G3DSA:3.40.50.1820 2296 2407 1.1E-36 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS26305 5d5fe5b47344d7b0570695bb3c294749 2564 Pfam PF13745 HxxPF-repeated domain 415 524 7.4E-21 T 10-11-2016 A4G23_RS26305 5d5fe5b47344d7b0570695bb3c294749 2564 SUPERFAMILY SSF52777 102 279 2.67E-47 T 10-11-2016 A4G23_RS26305 5d5fe5b47344d7b0570695bb3c294749 2564 Gene3D G3DSA:1.10.1200.10 2213 2275 8.2E-24 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS26305 5d5fe5b47344d7b0570695bb3c294749 2564 Gene3D G3DSA:1.10.1200.10 1143 1208 2.4E-24 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS26305 5d5fe5b47344d7b0570695bb3c294749 2564 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1849 1860 - T 10-11-2016 IPR020845 AMP-binding, conserved site A4G23_RS26305 5d5fe5b47344d7b0570695bb3c294749 2564 SUPERFAMILY SSF56801 1702 2222 1.22E-150 T 10-11-2016 A4G23_RS26305 5d5fe5b47344d7b0570695bb3c294749 2564 Pfam PF13193 AMP-binding enzyme C-terminal domain 2105 2181 3.0E-12 T 10-11-2016 IPR025110 AMP-binding enzyme C-terminal domain A4G23_RS26305 5d5fe5b47344d7b0570695bb3c294749 2564 Pfam PF13193 AMP-binding enzyme C-terminal domain 1038 1112 1.7E-14 T 10-11-2016 IPR025110 AMP-binding enzyme C-terminal domain A4G23_RS18755 89f5f459580afd161e4e850d872db42d 1222 Pfam PF00580 UvrD/REP helicase N-terminal domain 20 324 4.4E-48 T 10-11-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 A4G23_RS18755 89f5f459580afd161e4e850d872db42d 1222 SUPERFAMILY SSF52540 17 487 1.83E-113 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS18755 89f5f459580afd161e4e850d872db42d 1222 SUPERFAMILY SSF52540 725 771 1.83E-113 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS18755 89f5f459580afd161e4e850d872db42d 1222 SUPERFAMILY SSF52540 532 686 1.83E-113 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS18755 89f5f459580afd161e4e850d872db42d 1222 Pfam PF12705 PD-(D/E)XK nuclease superfamily 1020 1190 4.7E-9 T 10-11-2016 A4G23_RS18755 89f5f459580afd161e4e850d872db42d 1222 Pfam PF13361 UvrD-like helicase C-terminal domain 335 743 8.8E-27 T 10-11-2016 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 A4G23_RS18755 89f5f459580afd161e4e850d872db42d 1222 Gene3D G3DSA:3.40.50.300 721 771 1.7E-43 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS18755 89f5f459580afd161e4e850d872db42d 1222 Gene3D G3DSA:3.40.50.300 647 682 1.7E-43 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS18755 89f5f459580afd161e4e850d872db42d 1222 Gene3D G3DSA:3.40.50.300 339 451 1.7E-43 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS18755 89f5f459580afd161e4e850d872db42d 1222 Gene3D G3DSA:1.10.486.10 452 625 2.2E-24 T 10-11-2016 A4G23_RS18755 89f5f459580afd161e4e850d872db42d 1222 SUPERFAMILY SSF52980 1043 1181 3.16E-6 T 10-11-2016 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A4G23_RS18755 89f5f459580afd161e4e850d872db42d 1222 Gene3D G3DSA:3.40.50.300 206 325 2.4E-63 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS18755 89f5f459580afd161e4e850d872db42d 1222 Gene3D G3DSA:3.40.50.300 19 153 2.4E-63 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS01005 0a39db2c3cefda7ec42299319191fbbf 550 SUPERFAMILY SSF56634 3 501 3.53E-185 T 10-11-2016 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 A4G23_RS01005 0a39db2c3cefda7ec42299319191fbbf 550 PRINTS PR00067 Catalase signature 132 150 5.4E-63 T 10-11-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 A4G23_RS01005 0a39db2c3cefda7ec42299319191fbbf 550 PRINTS PR00067 Catalase signature 92 110 5.4E-63 T 10-11-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 A4G23_RS01005 0a39db2c3cefda7ec42299319191fbbf 550 PRINTS PR00067 Catalase signature 113 130 5.4E-63 T 10-11-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 A4G23_RS01005 0a39db2c3cefda7ec42299319191fbbf 550 PRINTS PR00067 Catalase signature 24 47 5.4E-63 T 10-11-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 A4G23_RS01005 0a39db2c3cefda7ec42299319191fbbf 550 PRINTS PR00067 Catalase signature 297 324 5.4E-63 T 10-11-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 A4G23_RS01005 0a39db2c3cefda7ec42299319191fbbf 550 PRINTS PR00067 Catalase signature 329 355 5.4E-63 T 10-11-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 A4G23_RS01005 0a39db2c3cefda7ec42299319191fbbf 550 Gene3D G3DSA:2.40.180.10 4 365 2.1E-159 T 10-11-2016 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 A4G23_RS01005 0a39db2c3cefda7ec42299319191fbbf 550 PIRSF PIRSF038928 2 497 4.2E-168 T 10-11-2016 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 A4G23_RS01005 0a39db2c3cefda7ec42299319191fbbf 550 Pfam PF00199 Catalase 11 404 8.7E-163 T 10-11-2016 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 A4G23_RS01005 0a39db2c3cefda7ec42299319191fbbf 550 SMART SM01060 11 410 4.8E-233 T 10-11-2016 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 A4G23_RS01005 0a39db2c3cefda7ec42299319191fbbf 550 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 342 350 - T 10-11-2016 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 A4G23_RS01005 0a39db2c3cefda7ec42299319191fbbf 550 Pfam PF06628 Catalase-related immune-responsive 435 494 3.8E-18 T 10-11-2016 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 A4G23_RS19115 6dd778fe006b05634c985fb6ec6f9286 220 SUPERFAMILY SSF52540 6 217 7.77E-54 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS19115 6dd778fe006b05634c985fb6ec6f9286 220 SMART SM00382 28 215 1.5E-13 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS19115 6dd778fe006b05634c985fb6ec6f9286 220 Gene3D G3DSA:3.40.50.300 5 216 1.4E-58 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS19115 6dd778fe006b05634c985fb6ec6f9286 220 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS19115 6dd778fe006b05634c985fb6ec6f9286 220 Pfam PF00005 ABC transporter 20 166 7.9E-31 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS25725 0eeaa643a004e9274a00bbb8e9c43681 286 SMART SM01232 136 228 8.9E-32 T 10-11-2016 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 A4G23_RS25725 0eeaa643a004e9274a00bbb8e9c43681 286 Gene3D G3DSA:1.10.8.50 137 271 6.5E-39 T 10-11-2016 A4G23_RS25725 0eeaa643a004e9274a00bbb8e9c43681 286 SUPERFAMILY SSF57716 229 270 1.48E-11 T 10-11-2016 A4G23_RS25725 0eeaa643a004e9274a00bbb8e9c43681 286 Pfam PF06827 Zinc finger found in FPG and IleRS 243 270 6.1E-9 T 10-11-2016 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 A4G23_RS25725 0eeaa643a004e9274a00bbb8e9c43681 286 SUPERFAMILY SSF46946 135 218 7.46E-26 T 10-11-2016 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 A4G23_RS25725 0eeaa643a004e9274a00bbb8e9c43681 286 Gene3D G3DSA:3.20.190.10 2 136 2.1E-19 T 10-11-2016 A4G23_RS25725 0eeaa643a004e9274a00bbb8e9c43681 286 SUPERFAMILY SSF81624 2 141 5.76E-25 T 10-11-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 A4G23_RS25725 0eeaa643a004e9274a00bbb8e9c43681 286 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 83 2.7E-15 T 10-11-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 A4G23_RS25725 0eeaa643a004e9274a00bbb8e9c43681 286 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 136 220 6.5E-21 T 10-11-2016 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 A4G23_RS25725 0eeaa643a004e9274a00bbb8e9c43681 286 SMART SM00898 2 122 6.0E-24 T 10-11-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 A4G23_RS12725 aab5941ec1edcbc1e5cc37af4644fe03 639 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 52 220 1.3E-16 T 10-11-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS12725 aab5941ec1edcbc1e5cc37af4644fe03 639 PRINTS PR01217 Proline rich extensin signature 452 477 6.4E-14 T 10-11-2016 A4G23_RS12725 aab5941ec1edcbc1e5cc37af4644fe03 639 PRINTS PR01217 Proline rich extensin signature 413 429 6.4E-14 T 10-11-2016 A4G23_RS12725 aab5941ec1edcbc1e5cc37af4644fe03 639 PRINTS PR01217 Proline rich extensin signature 434 451 6.4E-14 T 10-11-2016 A4G23_RS12725 aab5941ec1edcbc1e5cc37af4644fe03 639 PRINTS PR01217 Proline rich extensin signature 390 411 6.4E-14 T 10-11-2016 A4G23_RS12725 aab5941ec1edcbc1e5cc37af4644fe03 639 Gene3D G3DSA:1.10.1740.10 37 138 2.9E-20 T 10-11-2016 A4G23_RS12725 aab5941ec1edcbc1e5cc37af4644fe03 639 SUPERFAMILY SSF88659 159 219 3.55E-6 T 10-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS12725 aab5941ec1edcbc1e5cc37af4644fe03 639 SMART SM00776 492 636 2.5E-36 T 10-11-2016 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module A4G23_RS12725 aab5941ec1edcbc1e5cc37af4644fe03 639 Gene3D G3DSA:1.10.10.10 160 220 7.7E-5 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS12725 aab5941ec1edcbc1e5cc37af4644fe03 639 Pfam PF04542 Sigma-70 region 2 56 124 9.4E-10 T 10-11-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS12725 aab5941ec1edcbc1e5cc37af4644fe03 639 SUPERFAMILY SSF88946 36 134 1.18E-18 T 10-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS12725 aab5941ec1edcbc1e5cc37af4644fe03 639 SUPERFAMILY SSF49785 508 634 2.93E-33 T 10-11-2016 IPR008979 Galactose-binding domain-like A4G23_RS12725 aab5941ec1edcbc1e5cc37af4644fe03 639 Pfam PF08305 NPCBM/NEW2 domain 526 634 4.6E-29 T 10-11-2016 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module A4G23_RS07660 4f125cebcccc57dfb57e53da3038f190 479 Gene3D G3DSA:3.30.420.40 3 233 1.7E-36 T 10-11-2016 A4G23_RS07660 4f125cebcccc57dfb57e53da3038f190 479 Gene3D G3DSA:3.30.420.40 237 465 4.6E-26 T 10-11-2016 A4G23_RS07660 4f125cebcccc57dfb57e53da3038f190 479 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 337 358 - T 10-11-2016 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A4G23_RS07660 4f125cebcccc57dfb57e53da3038f190 479 PIRSF PIRSF000538 1 467 1.6E-64 T 10-11-2016 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A4G23_RS07660 4f125cebcccc57dfb57e53da3038f190 479 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 227 1.3E-33 T 10-11-2016 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 A4G23_RS07660 4f125cebcccc57dfb57e53da3038f190 479 SUPERFAMILY SSF53067 4 235 9.71E-36 T 10-11-2016 A4G23_RS07660 4f125cebcccc57dfb57e53da3038f190 479 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 241 425 7.2E-20 T 10-11-2016 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 A4G23_RS07660 4f125cebcccc57dfb57e53da3038f190 479 SUPERFAMILY SSF53067 236 455 1.94E-36 T 10-11-2016 A4G23_RS27190 b33372f73e3ce696c10782e17460d1a4 316 Pfam PF01636 Phosphotransferase enzyme family 52 245 1.1E-8 T 10-11-2016 IPR002575 Aminoglycoside phosphotransferase A4G23_RS27190 b33372f73e3ce696c10782e17460d1a4 316 Gene3D G3DSA:3.90.1200.10 127 244 1.8E-7 T 10-11-2016 A4G23_RS27190 b33372f73e3ce696c10782e17460d1a4 316 SUPERFAMILY SSF56112 33 245 1.62E-16 T 10-11-2016 IPR011009 Protein kinase-like domain A4G23_RS07040 2add7bdbfa7b635bc19cb029c30a6f43 291 PIRSF PIRSF016184 8 291 1.1E-57 T 10-11-2016 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 A4G23_RS07040 2add7bdbfa7b635bc19cb029c30a6f43 291 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 10 288 3.2E-46 T 10-11-2016 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 A4G23_RS07040 2add7bdbfa7b635bc19cb029c30a6f43 291 Gene3D G3DSA:3.10.310.10 139 280 1.3E-35 T 10-11-2016 A4G23_RS07040 2add7bdbfa7b635bc19cb029c30a6f43 291 SUPERFAMILY SSF54506 11 289 9.42E-55 T 10-11-2016 A4G23_RS07040 2add7bdbfa7b635bc19cb029c30a6f43 291 Gene3D G3DSA:3.10.310.10 11 127 4.8E-33 T 10-11-2016 A4G23_RS07040 2add7bdbfa7b635bc19cb029c30a6f43 291 Pfam PF02567 Phenazine biosynthesis-like protein 16 289 3.8E-61 T 10-11-2016 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 A4G23_RS03995 1026fa5d77ded171354c58c7ebc0da8c 400 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 11 387 43.471 T 10-11-2016 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 A4G23_RS03995 1026fa5d77ded171354c58c7ebc0da8c 400 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 16 386 1.9E-138 T 10-11-2016 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 A4G23_RS03995 1026fa5d77ded171354c58c7ebc0da8c 400 Gene3D G3DSA:3.40.640.10 58 294 3.0E-86 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS03995 1026fa5d77ded171354c58c7ebc0da8c 400 Gene3D G3DSA:3.90.1150.10 298 388 7.2E-38 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS03995 1026fa5d77ded171354c58c7ebc0da8c 400 Gene3D G3DSA:3.90.1150.10 2 57 7.2E-38 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS03995 1026fa5d77ded171354c58c7ebc0da8c 400 SUPERFAMILY SSF53383 14 388 3.34E-123 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS03995 1026fa5d77ded171354c58c7ebc0da8c 400 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 214 251 - T 10-11-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4G23_RS03995 1026fa5d77ded171354c58c7ebc0da8c 400 Pfam PF00202 Aminotransferase class-III 21 382 1.4E-105 T 10-11-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4G23_RS18585 ffc0a7bda5bbee449465d2d1a0133976 377 SUPERFAMILY SSF117916 1 90 1.8E-23 T 10-11-2016 A4G23_RS18585 ffc0a7bda5bbee449465d2d1a0133976 377 Pfam PF01883 Domain of unknown function DUF59 4 76 2.0E-16 T 10-11-2016 IPR002744 Domain of unknown function DUF59 A4G23_RS18585 ffc0a7bda5bbee449465d2d1a0133976 377 Gene3D G3DSA:3.40.50.300 100 356 1.6E-89 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS18585 ffc0a7bda5bbee449465d2d1a0133976 377 SUPERFAMILY SSF52540 111 360 1.72E-53 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS18585 ffc0a7bda5bbee449465d2d1a0133976 377 Hamap MF_02040 Iron-sulfur cluster carrier protein. 102 358 34.985 T 10-11-2016 IPR019591 Mrp/NBP35 ATP-binding protein A4G23_RS18585 ffc0a7bda5bbee449465d2d1a0133976 377 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 111 357 4.2E-92 T 10-11-2016 IPR019591 Mrp/NBP35 ATP-binding protein A4G23_RS18585 ffc0a7bda5bbee449465d2d1a0133976 377 ProSitePatterns PS01215 Mrp family signature. 215 231 - T 10-11-2016 IPR000808 Mrp, conserved site GO:0005524 A4G23_RS03605 ec52cb5de24cfa8daa18f2793d998982 364 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 20 347 1.4E-105 T 10-11-2016 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 A4G23_RS03605 ec52cb5de24cfa8daa18f2793d998982 364 SUPERFAMILY SSF56796 18 359 6.8E-98 T 10-11-2016 A4G23_RS03605 ec52cb5de24cfa8daa18f2793d998982 364 Pfam PF01761 3-dehydroquinate synthase 72 328 1.1E-91 T 10-11-2016 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 A4G23_RS03605 ec52cb5de24cfa8daa18f2793d998982 364 Gene3D G3DSA:1.20.1090.10 178 358 1.4E-57 T 10-11-2016 A4G23_RS03605 ec52cb5de24cfa8daa18f2793d998982 364 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 9 361 36.122 T 10-11-2016 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 A4G23_RS03605 ec52cb5de24cfa8daa18f2793d998982 364 Gene3D G3DSA:3.40.50.1970 15 176 1.4E-54 T 10-11-2016 A4G23_RS03605 ec52cb5de24cfa8daa18f2793d998982 364 PIRSF PIRSF001455 14 362 9.1E-99 T 10-11-2016 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 A4G23_RS09445 067ac9ea6d91efc4873e1774dab46e68 170 SUPERFAMILY SSF50118 69 165 6.32E-9 T 10-11-2016 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor A4G23_RS09445 067ac9ea6d91efc4873e1774dab46e68 170 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 71 164 9.9E-6 T 10-11-2016 IPR003477 mRNA interferase PemK-like protein GO:0003677 A4G23_RS20035 505560aebed64af2c3b758b9e34501a5 243 SMART SM00644 71 200 6.5E-39 T 10-11-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 A4G23_RS20035 505560aebed64af2c3b758b9e34501a5 243 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 82 201 5.6E-22 T 10-11-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 A4G23_RS20035 505560aebed64af2c3b758b9e34501a5 243 Gene3D G3DSA:3.40.80.10 70 216 1.4E-41 T 10-11-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 A4G23_RS20035 505560aebed64af2c3b758b9e34501a5 243 SUPERFAMILY SSF55846 63 214 1.31E-41 T 10-11-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 A4G23_RS02670 54da38b8c413b25fcfab5d4055f081e1 608 Pfam PF00271 Helicase conserved C-terminal domain 425 533 2.4E-5 T 10-11-2016 IPR001650 Helicase, C-terminal A4G23_RS02670 54da38b8c413b25fcfab5d4055f081e1 608 SUPERFAMILY SSF52540 414 575 1.78E-30 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS02670 54da38b8c413b25fcfab5d4055f081e1 608 SUPERFAMILY SSF52540 232 288 1.78E-30 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS02670 54da38b8c413b25fcfab5d4055f081e1 608 SMART SM00490 453 533 0.0056 T 10-11-2016 IPR001650 Helicase, C-terminal A4G23_RS02670 54da38b8c413b25fcfab5d4055f081e1 608 Gene3D G3DSA:3.40.50.300 123 284 1.8E-11 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS02670 54da38b8c413b25fcfab5d4055f081e1 608 SMART SM00487 119 297 1.8E-6 T 10-11-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4G23_RS02670 54da38b8c413b25fcfab5d4055f081e1 608 Pfam PF00176 SNF2 family N-terminal domain 170 349 2.2E-16 T 10-11-2016 IPR000330 SNF2-related, N-terminal domain GO:0005524 A4G23_RS02670 54da38b8c413b25fcfab5d4055f081e1 608 SUPERFAMILY SSF52540 109 291 2.08E-27 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS02670 54da38b8c413b25fcfab5d4055f081e1 608 Gene3D G3DSA:3.40.50.300 421 533 1.7E-6 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS18540 0747dd7425a3352f1617a640276f660d 212 Gene3D G3DSA:1.10.340.30 14 192 1.3E-70 T 10-11-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A4G23_RS18540 0747dd7425a3352f1617a640276f660d 212 SUPERFAMILY SSF48150 14 193 5.1E-68 T 10-11-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A4G23_RS18540 0747dd7425a3352f1617a640276f660d 212 Pfam PF03352 Methyladenine glycosylase 18 190 3.4E-65 T 10-11-2016 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 A4G23_RS22080 4cbb14419825f91e482c7bf688814651 373 Gene3D G3DSA:1.25.10.10 142 245 5.7E-5 T 10-11-2016 IPR011989 Armadillo-like helical A4G23_RS22080 4cbb14419825f91e482c7bf688814651 373 SUPERFAMILY SSF48371 41 247 1.44E-41 T 10-11-2016 IPR016024 Armadillo-type fold GO:0005488 A4G23_RS22080 4cbb14419825f91e482c7bf688814651 373 Pfam PF08713 DNA alkylation repair enzyme 127 240 1.4E-5 T 10-11-2016 IPR014825 DNA alkylation repair enzyme A4G23_RS03360 4c75f863d7ec6580cdfbe3d8d338a5fc 161 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 17 151 5.7E-42 T 10-11-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4G23_RS03360 4c75f863d7ec6580cdfbe3d8d338a5fc 161 SUPERFAMILY SSF52121 11 156 3.27E-54 T 10-11-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4G23_RS03360 4c75f863d7ec6580cdfbe3d8d338a5fc 161 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 12 156 28.354 T 10-11-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4G23_RS03360 4c75f863d7ec6580cdfbe3d8d338a5fc 161 Gene3D G3DSA:3.40.50.960 13 157 3.6E-57 T 10-11-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4G23_RS03360 4c75f863d7ec6580cdfbe3d8d338a5fc 161 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 17 151 9.9E-51 T 10-11-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4G23_RS04120 b2d061959eac1a7e286c7acd6ed41e60 64 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 10-11-2016 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS04120 b2d061959eac1a7e286c7acd6ed41e60 64 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 62 1.8E-26 T 10-11-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 A4G23_RS04120 b2d061959eac1a7e286c7acd6ed41e60 64 PRINTS PR00064 Ribosomal protein L35 signature 36 54 2.8E-17 T 10-11-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 A4G23_RS04120 b2d061959eac1a7e286c7acd6ed41e60 64 PRINTS PR00064 Ribosomal protein L35 signature 21 35 2.8E-17 T 10-11-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 A4G23_RS04120 b2d061959eac1a7e286c7acd6ed41e60 64 PRINTS PR00064 Ribosomal protein L35 signature 3 20 2.8E-17 T 10-11-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 A4G23_RS04120 b2d061959eac1a7e286c7acd6ed41e60 64 Pfam PF01632 Ribosomal protein L35 2 62 1.7E-24 T 10-11-2016 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS04120 b2d061959eac1a7e286c7acd6ed41e60 64 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 17.852 T 10-11-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 A4G23_RS04120 b2d061959eac1a7e286c7acd6ed41e60 64 SUPERFAMILY SSF143034 2 63 3.53E-22 T 10-11-2016 A4G23_RS24580 465590e25cba4a39ca04e32a9b4f4857 565 Pfam PF00733 Asparagine synthase 207 549 2.5E-35 T 10-11-2016 IPR001962 Asparagine synthase GO:0004066|GO:0006529 A4G23_RS24580 465590e25cba4a39ca04e32a9b4f4857 565 SUPERFAMILY SSF52402 403 521 4.19E-32 T 10-11-2016 A4G23_RS24580 465590e25cba4a39ca04e32a9b4f4857 565 SUPERFAMILY SSF52402 178 333 4.19E-32 T 10-11-2016 A4G23_RS24580 465590e25cba4a39ca04e32a9b4f4857 565 Gene3D G3DSA:3.60.20.10 74 181 2.4E-14 T 10-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal A4G23_RS24580 465590e25cba4a39ca04e32a9b4f4857 565 Gene3D G3DSA:3.40.50.620 401 525 8.6E-28 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS24580 465590e25cba4a39ca04e32a9b4f4857 565 Gene3D G3DSA:3.40.50.620 182 331 8.6E-28 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS24580 465590e25cba4a39ca04e32a9b4f4857 565 PIRSF PIRSF001589 65 564 2.2E-34 T 10-11-2016 A4G23_RS24580 465590e25cba4a39ca04e32a9b4f4857 565 SUPERFAMILY SSF56235 55 181 2.98E-11 T 10-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal A4G23_RS14575 bbad20a46cc2d4ed2eb21ab7a4de6efa 298 Pfam PF00005 ABC transporter 20 159 3.4E-23 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS14575 bbad20a46cc2d4ed2eb21ab7a4de6efa 298 Gene3D G3DSA:3.40.50.300 2 220 3.9E-60 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS14575 bbad20a46cc2d4ed2eb21ab7a4de6efa 298 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS14575 bbad20a46cc2d4ed2eb21ab7a4de6efa 298 SMART SM00382 29 207 9.2E-11 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS14575 bbad20a46cc2d4ed2eb21ab7a4de6efa 298 Pfam PF13732 Domain of unknown function (DUF4162) 212 289 7.5E-7 T 10-11-2016 IPR025302 Domain of unknown function DUF4162 A4G23_RS14575 bbad20a46cc2d4ed2eb21ab7a4de6efa 298 SUPERFAMILY SSF52540 4 219 3.68E-54 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS16920 0d04e73cdb451addd001de01d7fcb248 102 PRINTS PR00297 10kDa chaperonin signature 10 25 9.6E-31 T 10-11-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A4G23_RS16920 0d04e73cdb451addd001de01d7fcb248 102 PRINTS PR00297 10kDa chaperonin signature 66 78 9.6E-31 T 10-11-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A4G23_RS16920 0d04e73cdb451addd001de01d7fcb248 102 PRINTS PR00297 10kDa chaperonin signature 32 53 9.6E-31 T 10-11-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A4G23_RS16920 0d04e73cdb451addd001de01d7fcb248 102 PRINTS PR00297 10kDa chaperonin signature 87 100 9.6E-31 T 10-11-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A4G23_RS16920 0d04e73cdb451addd001de01d7fcb248 102 SUPERFAMILY SSF50129 9 101 1.88E-32 T 10-11-2016 IPR011032 GroES-like A4G23_RS16920 0d04e73cdb451addd001de01d7fcb248 102 Gene3D G3DSA:2.30.33.40 10 101 1.0E-36 T 10-11-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A4G23_RS16920 0d04e73cdb451addd001de01d7fcb248 102 Hamap MF_00580 10 kDa chaperonin [groS]. 9 101 25.426 T 10-11-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A4G23_RS16920 0d04e73cdb451addd001de01d7fcb248 102 ProSitePatterns PS00681 Chaperonins cpn10 signature. 10 34 - T 10-11-2016 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 A4G23_RS16920 0d04e73cdb451addd001de01d7fcb248 102 Pfam PF00166 Chaperonin 10 Kd subunit 10 100 7.3E-33 T 10-11-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A4G23_RS16920 0d04e73cdb451addd001de01d7fcb248 102 SMART SM00883 9 100 4.2E-51 T 10-11-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A4G23_RS11815 1f83ec59043fe9c129a960287d0305f5 276 Pfam PF13560 Helix-turn-helix domain 18 73 1.4E-10 T 10-11-2016 A4G23_RS11815 1f83ec59043fe9c129a960287d0305f5 276 Gene3D G3DSA:1.10.260.40 16 72 1.6E-10 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS11815 1f83ec59043fe9c129a960287d0305f5 276 SUPERFAMILY SSF47413 14 64 1.07E-8 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS11815 1f83ec59043fe9c129a960287d0305f5 276 SMART SM00530 21 76 1.3E-6 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS21185 d58575327a84d9fee245af256264d553 597 Gene3D G3DSA:3.50.50.60 104 105 6.4E-41 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS21185 d58575327a84d9fee245af256264d553 597 Gene3D G3DSA:3.50.50.60 327 408 6.4E-41 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS21185 d58575327a84d9fee245af256264d553 597 Gene3D G3DSA:3.50.50.60 4 69 6.4E-41 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS21185 d58575327a84d9fee245af256264d553 597 Gene3D G3DSA:3.50.50.60 156 238 6.4E-41 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS21185 d58575327a84d9fee245af256264d553 597 SUPERFAMILY SSF51905 3 89 4.72E-40 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS21185 d58575327a84d9fee245af256264d553 597 SUPERFAMILY SSF51905 326 425 4.72E-40 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS21185 d58575327a84d9fee245af256264d553 597 SUPERFAMILY SSF51905 164 233 4.72E-40 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS21185 d58575327a84d9fee245af256264d553 597 Pfam PF01494 FAD binding domain 3 403 1.0E-42 T 10-11-2016 IPR002938 FAD-binding domain GO:0071949 A4G23_RS21185 d58575327a84d9fee245af256264d553 597 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 354 370 7.0E-23 T 10-11-2016 A4G23_RS21185 d58575327a84d9fee245af256264d553 597 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 372 390 7.0E-23 T 10-11-2016 A4G23_RS21185 d58575327a84d9fee245af256264d553 597 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 7.0E-23 T 10-11-2016 A4G23_RS21185 d58575327a84d9fee245af256264d553 597 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 212 227 7.0E-23 T 10-11-2016 A4G23_RS21185 d58575327a84d9fee245af256264d553 597 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 339 354 7.0E-23 T 10-11-2016 A4G23_RS19225 e4c48a47affabef17ea1ec36ccdbbed3 245 Pfam PF00072 Response regulator receiver domain 21 129 6.9E-27 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS19225 e4c48a47affabef17ea1ec36ccdbbed3 245 SMART SM00862 169 240 4.0E-25 T 10-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4G23_RS19225 e4c48a47affabef17ea1ec36ccdbbed3 245 SUPERFAMILY SSF46894 147 241 9.92E-27 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS19225 e4c48a47affabef17ea1ec36ccdbbed3 245 Gene3D G3DSA:1.10.10.10 147 242 1.9E-31 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS19225 e4c48a47affabef17ea1ec36ccdbbed3 245 SUPERFAMILY SSF52172 15 138 2.56E-41 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS19225 e4c48a47affabef17ea1ec36ccdbbed3 245 Gene3D G3DSA:3.40.50.2300 16 137 3.3E-39 T 10-11-2016 A4G23_RS19225 e4c48a47affabef17ea1ec36ccdbbed3 245 Pfam PF00486 Transcriptional regulatory protein, C terminal 170 240 1.2E-23 T 10-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4G23_RS19225 e4c48a47affabef17ea1ec36ccdbbed3 245 SMART SM00448 19 129 2.1E-41 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS26605 cc1af09f6bed740a44031092b1971852 122 TIGRFAM TIGR01068 thioredoxin: thioredoxin 7 102 1.0E-31 T 10-11-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 A4G23_RS26605 cc1af09f6bed740a44031092b1971852 122 PIRSF PIRSF000077 1 104 1.2E-27 T 10-11-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 A4G23_RS26605 cc1af09f6bed740a44031092b1971852 122 PRINTS PR00421 Thioredoxin family signature 68 79 5.6E-8 T 10-11-2016 A4G23_RS26605 cc1af09f6bed740a44031092b1971852 122 PRINTS PR00421 Thioredoxin family signature 29 38 5.6E-8 T 10-11-2016 A4G23_RS26605 cc1af09f6bed740a44031092b1971852 122 PRINTS PR00421 Thioredoxin family signature 21 29 5.6E-8 T 10-11-2016 A4G23_RS26605 cc1af09f6bed740a44031092b1971852 122 Gene3D G3DSA:3.40.30.10 3 101 1.0E-32 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS26605 cc1af09f6bed740a44031092b1971852 122 SUPERFAMILY SSF52833 4 103 3.57E-32 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS26605 cc1af09f6bed740a44031092b1971852 122 Pfam PF00085 Thioredoxin 4 101 4.2E-27 T 10-11-2016 IPR013766 Thioredoxin domain GO:0045454 A4G23_RS26605 cc1af09f6bed740a44031092b1971852 122 ProSitePatterns PS00194 Thioredoxin family active site. 22 40 - T 10-11-2016 IPR017937 Thioredoxin, conserved site GO:0045454 A4G23_RS26700 d6408560e85ed41cdfad2195dd598f75 406 ProSitePatterns PS00375 UDP-glycosyltransferases signature. 297 338 - T 10-11-2016 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 A4G23_RS26700 d6408560e85ed41cdfad2195dd598f75 406 SUPERFAMILY SSF53756 14 404 3.93E-75 T 10-11-2016 A4G23_RS26700 d6408560e85ed41cdfad2195dd598f75 406 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 19 404 2.3E-102 T 10-11-2016 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 A4G23_RS26700 d6408560e85ed41cdfad2195dd598f75 406 Gene3D G3DSA:3.40.50.2000 238 385 1.8E-33 T 10-11-2016 A4G23_RS26700 d6408560e85ed41cdfad2195dd598f75 406 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 236 376 1.1E-18 T 10-11-2016 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 A4G23_RS26700 d6408560e85ed41cdfad2195dd598f75 406 Gene3D G3DSA:3.40.50.2000 14 203 1.5E-6 T 10-11-2016 A4G23_RS13470 d1d7f6c6bb566dc9508a8f53b47a7fcd 600 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 3 598 32.024 T 10-11-2016 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 A4G23_RS13470 d1d7f6c6bb566dc9508a8f53b47a7fcd 600 SUPERFAMILY SSF48295 503 599 2.09E-34 T 10-11-2016 IPR010921 Trp repressor/replication initiator GO:0043565 A4G23_RS13470 d1d7f6c6bb566dc9508a8f53b47a7fcd 600 Gene3D G3DSA:1.10.1750.10 502 599 1.6E-38 T 10-11-2016 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 A4G23_RS13470 d1d7f6c6bb566dc9508a8f53b47a7fcd 600 SUPERFAMILY SSF52540 260 472 5.4E-45 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS13470 d1d7f6c6bb566dc9508a8f53b47a7fcd 600 ProSitePatterns PS01008 DnaA protein signature. 557 576 - T 10-11-2016 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 A4G23_RS13470 d1d7f6c6bb566dc9508a8f53b47a7fcd 600 Gene3D G3DSA:3.40.50.300 258 425 1.3E-61 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS13470 d1d7f6c6bb566dc9508a8f53b47a7fcd 600 SMART SM00760 507 576 1.1E-36 T 10-11-2016 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 A4G23_RS13470 d1d7f6c6bb566dc9508a8f53b47a7fcd 600 Gene3D G3DSA:1.10.8.60 427 496 1.2E-28 T 10-11-2016 A4G23_RS13470 d1d7f6c6bb566dc9508a8f53b47a7fcd 600 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 510 576 6.7E-30 T 10-11-2016 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 A4G23_RS13470 d1d7f6c6bb566dc9508a8f53b47a7fcd 600 SMART SM00382 293 421 1.5E-10 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS13470 d1d7f6c6bb566dc9508a8f53b47a7fcd 600 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 18 597 4.6E-155 T 10-11-2016 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 A4G23_RS13470 d1d7f6c6bb566dc9508a8f53b47a7fcd 600 Pfam PF00308 Bacterial dnaA protein 261 478 1.7E-103 T 10-11-2016 IPR013317 Chromosomal replication initiator protein DnaA A4G23_RS13470 d1d7f6c6bb566dc9508a8f53b47a7fcd 600 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 294 314 2.7E-52 T 10-11-2016 IPR020591 Chromosomal replication control, initiator DnaA-like A4G23_RS13470 d1d7f6c6bb566dc9508a8f53b47a7fcd 600 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 326 340 2.7E-52 T 10-11-2016 IPR020591 Chromosomal replication control, initiator DnaA-like A4G23_RS13470 d1d7f6c6bb566dc9508a8f53b47a7fcd 600 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 358 372 2.7E-52 T 10-11-2016 IPR020591 Chromosomal replication control, initiator DnaA-like A4G23_RS13470 d1d7f6c6bb566dc9508a8f53b47a7fcd 600 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 392 419 2.7E-52 T 10-11-2016 IPR020591 Chromosomal replication control, initiator DnaA-like A4G23_RS13470 d1d7f6c6bb566dc9508a8f53b47a7fcd 600 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 557 576 2.7E-52 T 10-11-2016 IPR020591 Chromosomal replication control, initiator DnaA-like A4G23_RS22145 241ea4e84924e16a53e7db370b4a22f1 347 SUPERFAMILY SSF53807 54 343 1.37E-51 T 10-11-2016 A4G23_RS22145 241ea4e84924e16a53e7db370b4a22f1 347 Pfam PF01497 Periplasmic binding protein 78 320 1.3E-36 T 10-11-2016 IPR002491 ABC transporter periplasmic binding domain GO:0005488 A4G23_RS22145 241ea4e84924e16a53e7db370b4a22f1 347 Gene3D G3DSA:3.40.50.1980 211 344 1.6E-31 T 10-11-2016 A4G23_RS22145 241ea4e84924e16a53e7db370b4a22f1 347 Gene3D G3DSA:3.40.50.1980 63 195 2.4E-16 T 10-11-2016 A4G23_RS14335 6fe0aa807350b22f7c3cc57682a02348 191 Gene3D G3DSA:2.60.60.30 18 184 4.0E-75 T 10-11-2016 A4G23_RS14335 6fe0aa807350b22f7c3cc57682a02348 191 Pfam PF02342 TerD domain 1 187 2.2E-86 T 10-11-2016 IPR003325 TerD domain GO:0006950 A4G23_RS06065 1a172775ea156e8a20db829e6f0fbda2 370 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 10 365 54.217 T 10-11-2016 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 A4G23_RS06065 1a172775ea156e8a20db829e6f0fbda2 370 Pfam PF00155 Aminotransferase class I and II 30 361 4.5E-63 T 10-11-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4G23_RS06065 1a172775ea156e8a20db829e6f0fbda2 370 SUPERFAMILY SSF53383 29 364 2.75E-76 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS06065 1a172775ea156e8a20db829e6f0fbda2 370 Gene3D G3DSA:3.40.640.10 47 271 5.3E-64 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS06065 1a172775ea156e8a20db829e6f0fbda2 370 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 12 363 1.5E-95 T 10-11-2016 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 A4G23_RS06065 1a172775ea156e8a20db829e6f0fbda2 370 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 228 237 - T 10-11-2016 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 A4G23_RS06065 1a172775ea156e8a20db829e6f0fbda2 370 Gene3D G3DSA:3.90.1150.10 272 366 5.0E-17 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS21880 1a1205e32a047d530093b3f7b1c74570 139 Pfam PF03259 Roadblock/LC7 domain 9 101 8.0E-25 T 10-11-2016 IPR004942 Roadblock/LAMTOR2 domain A4G23_RS21880 1a1205e32a047d530093b3f7b1c74570 139 SUPERFAMILY SSF103196 2 130 2.62E-32 T 10-11-2016 A4G23_RS21880 1a1205e32a047d530093b3f7b1c74570 139 Gene3D G3DSA:3.30.450.30 6 127 3.9E-29 T 10-11-2016 A4G23_RS21880 1a1205e32a047d530093b3f7b1c74570 139 SMART SM00960 9 101 3.6E-25 T 10-11-2016 IPR004942 Roadblock/LAMTOR2 domain A4G23_RS13580 025a930ad9411c7d400562d05ff4102d 343 SUPERFAMILY SSF51419 15 176 6.87E-14 T 10-11-2016 IPR029066 PLP-binding barrel A4G23_RS13580 025a930ad9411c7d400562d05ff4102d 343 Gene3D G3DSA:3.20.20.10 26 172 2.0E-13 T 10-11-2016 IPR029066 PLP-binding barrel A4G23_RS13580 025a930ad9411c7d400562d05ff4102d 343 Pfam PF01168 Alanine racemase, N-terminal domain 12 153 6.1E-12 T 10-11-2016 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4G23_RS07990 b693182f4bbf54dcd78ef11773704452 641 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 264 394 5.9E-10 T 10-11-2016 IPR003959 ATPase, AAA-type, core GO:0005524 A4G23_RS07990 b693182f4bbf54dcd78ef11773704452 641 SUPERFAMILY SSF52540 4 136 3.46E-15 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS07990 b693182f4bbf54dcd78ef11773704452 641 SUPERFAMILY SSF52540 310 394 3.46E-15 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS07990 b693182f4bbf54dcd78ef11773704452 641 Gene3D G3DSA:3.40.50.300 7 177 2.0E-17 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS07990 b693182f4bbf54dcd78ef11773704452 641 Gene3D G3DSA:3.40.50.300 257 396 2.0E-17 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS20525 3e483967bec1f0f761e2bf82c4b22476 255 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 40 224 6.9E-37 T 10-11-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A4G23_RS20525 3e483967bec1f0f761e2bf82c4b22476 255 Pfam PF10502 Signal peptidase, peptidase S26 126 217 7.0E-6 T 10-11-2016 IPR019533 Peptidase S26 A4G23_RS20525 3e483967bec1f0f761e2bf82c4b22476 255 ProSitePatterns PS00761 Signal peptidases I signature 3. 183 196 - T 10-11-2016 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 A4G23_RS20525 3e483967bec1f0f761e2bf82c4b22476 255 Gene3D G3DSA:2.10.109.10 49 140 1.8E-38 T 10-11-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain A4G23_RS20525 3e483967bec1f0f761e2bf82c4b22476 255 Gene3D G3DSA:2.10.109.10 178 231 1.8E-38 T 10-11-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain A4G23_RS20525 3e483967bec1f0f761e2bf82c4b22476 255 SUPERFAMILY SSF51306 125 230 6.28E-47 T 10-11-2016 IPR015927 Peptidase S24/S26A/S26B/S26C A4G23_RS20525 3e483967bec1f0f761e2bf82c4b22476 255 SUPERFAMILY SSF51306 49 97 6.28E-47 T 10-11-2016 IPR015927 Peptidase S24/S26A/S26B/S26C A4G23_RS20525 3e483967bec1f0f761e2bf82c4b22476 255 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 130 142 3.4E-22 T 10-11-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A4G23_RS20525 3e483967bec1f0f761e2bf82c4b22476 255 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 50 66 3.4E-22 T 10-11-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A4G23_RS20525 3e483967bec1f0f761e2bf82c4b22476 255 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 178 197 3.4E-22 T 10-11-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A4G23_RS20525 3e483967bec1f0f761e2bf82c4b22476 255 Pfam PF00717 Peptidase S24-like 56 97 1.2E-11 T 10-11-2016 IPR019759 Peptidase S24/S26A/S26B A4G23_RS19685 ffaa296fe1fdf4f0b33e09ebe07d1cc1 385 PIRSF PIRSF000429 1 381 3.9E-112 T 10-11-2016 IPR002155 Thiolase GO:0008152|GO:0016747 A4G23_RS19685 ffaa296fe1fdf4f0b33e09ebe07d1cc1 385 ProSitePatterns PS00099 Thiolases active site. 361 374 - T 10-11-2016 IPR020610 Thiolase, active site GO:0008152|GO:0016747 A4G23_RS19685 ffaa296fe1fdf4f0b33e09ebe07d1cc1 385 Pfam PF02803 Thiolase, C-terminal domain 258 378 4.5E-43 T 10-11-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 A4G23_RS19685 ffaa296fe1fdf4f0b33e09ebe07d1cc1 385 Pfam PF00108 Thiolase, N-terminal domain 1 249 1.1E-90 T 10-11-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 A4G23_RS19685 ffaa296fe1fdf4f0b33e09ebe07d1cc1 385 SUPERFAMILY SSF53901 259 378 4.4E-35 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS19685 ffaa296fe1fdf4f0b33e09ebe07d1cc1 385 SUPERFAMILY SSF53901 2 257 2.42E-82 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS19685 ffaa296fe1fdf4f0b33e09ebe07d1cc1 385 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 71 89 - T 10-11-2016 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 A4G23_RS19685 ffaa296fe1fdf4f0b33e09ebe07d1cc1 385 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 3 377 6.7E-131 T 10-11-2016 IPR002155 Thiolase GO:0008152|GO:0016747 A4G23_RS19685 ffaa296fe1fdf4f0b33e09ebe07d1cc1 385 Gene3D G3DSA:3.40.47.10 181 263 1.6E-67 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS19685 ffaa296fe1fdf4f0b33e09ebe07d1cc1 385 Gene3D G3DSA:3.40.47.10 2 110 1.6E-67 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS19685 ffaa296fe1fdf4f0b33e09ebe07d1cc1 385 Gene3D G3DSA:3.40.47.10 129 180 2.3E-53 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS19685 ffaa296fe1fdf4f0b33e09ebe07d1cc1 385 Gene3D G3DSA:3.40.47.10 264 379 2.3E-53 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS19685 ffaa296fe1fdf4f0b33e09ebe07d1cc1 385 ProSitePatterns PS00737 Thiolases signature 2. 326 342 - T 10-11-2016 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 A4G23_RS19325 402975876b2a229a236cc6846f434292 406 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 300 395 2.7E-8 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS19325 402975876b2a229a236cc6846f434292 406 Gene3D G3DSA:3.30.565.10 282 401 7.4E-14 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS19325 402975876b2a229a236cc6846f434292 406 SMART SM00387 298 396 3.8E-7 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS19325 402975876b2a229a236cc6846f434292 406 SUPERFAMILY SSF55874 265 396 2.49E-21 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS19325 402975876b2a229a236cc6846f434292 406 Pfam PF07730 Histidine kinase 193 260 2.2E-17 T 10-11-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4G23_RS19325 402975876b2a229a236cc6846f434292 406 PRINTS PR00344 Bacterial sensor protein C-terminal signature 380 393 1.9E-6 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS19325 402975876b2a229a236cc6846f434292 406 PRINTS PR00344 Bacterial sensor protein C-terminal signature 334 348 1.9E-6 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS19325 402975876b2a229a236cc6846f434292 406 PRINTS PR00344 Bacterial sensor protein C-terminal signature 356 374 1.9E-6 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS19325 402975876b2a229a236cc6846f434292 406 PIRSF PIRSF037434 1 401 6.7E-134 T 10-11-2016 IPR017205 Signal transduction histidine kinase, ChrS A4G23_RS20585 f40397e88df35a5364f2b9d88e95c442 300 Pfam PF00318 Ribosomal protein S2 9 225 2.8E-95 T 10-11-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS20585 f40397e88df35a5364f2b9d88e95c442 300 SUPERFAMILY SSF52313 6 230 1.44E-90 T 10-11-2016 IPR023591 Ribosomal protein S2, flavodoxin-like domain A4G23_RS20585 f40397e88df35a5364f2b9d88e95c442 300 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 10-11-2016 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 A4G23_RS20585 f40397e88df35a5364f2b9d88e95c442 300 Gene3D G3DSA:1.10.287.610 100 153 7.6E-21 T 10-11-2016 A4G23_RS20585 f40397e88df35a5364f2b9d88e95c442 300 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 226 42.097 T 10-11-2016 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 A4G23_RS20585 f40397e88df35a5364f2b9d88e95c442 300 PRINTS PR00395 Ribosomal protein S2 signature 176 187 7.3E-39 T 10-11-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS20585 f40397e88df35a5364f2b9d88e95c442 300 PRINTS PR00395 Ribosomal protein S2 signature 6 24 7.3E-39 T 10-11-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS20585 f40397e88df35a5364f2b9d88e95c442 300 PRINTS PR00395 Ribosomal protein S2 signature 197 211 7.3E-39 T 10-11-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS20585 f40397e88df35a5364f2b9d88e95c442 300 PRINTS PR00395 Ribosomal protein S2 signature 159 176 7.3E-39 T 10-11-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS20585 f40397e88df35a5364f2b9d88e95c442 300 PRINTS PR00395 Ribosomal protein S2 signature 87 104 7.3E-39 T 10-11-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS20585 f40397e88df35a5364f2b9d88e95c442 300 PRINTS PR00395 Ribosomal protein S2 signature 37 46 7.3E-39 T 10-11-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS20585 f40397e88df35a5364f2b9d88e95c442 300 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 225 5.9E-107 T 10-11-2016 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 A4G23_RS20585 f40397e88df35a5364f2b9d88e95c442 300 Gene3D G3DSA:3.40.50.10490 23 99 2.8E-67 T 10-11-2016 A4G23_RS20585 f40397e88df35a5364f2b9d88e95c442 300 Gene3D G3DSA:3.40.50.10490 159 247 2.8E-67 T 10-11-2016 A4G23_RS20135 2f9ed9494d40b6c1d2b712566c509d10 529 SUPERFAMILY SSF143548 321 450 1.1E-33 T 10-11-2016 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 A4G23_RS20135 2f9ed9494d40b6c1d2b712566c509d10 529 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 109 282 6.9E-63 T 10-11-2016 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A4G23_RS20135 2f9ed9494d40b6c1d2b712566c509d10 529 SUPERFAMILY SSF51735 103 282 4.6E-59 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS20135 2f9ed9494d40b6c1d2b712566c509d10 529 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 145 172 - T 10-11-2016 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 A4G23_RS20135 2f9ed9494d40b6c1d2b712566c509d10 529 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 193 215 - T 10-11-2016 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A4G23_RS20135 2f9ed9494d40b6c1d2b712566c509d10 529 SUPERFAMILY SSF52283 4 136 7.18E-36 T 10-11-2016 A4G23_RS20135 2f9ed9494d40b6c1d2b712566c509d10 529 TIGRFAM TIGR01327 PGDH: phosphoglycerate dehydrogenase 7 522 7.4E-190 T 10-11-2016 IPR006236 D-3-phosphoglycerate dehydrogenase GO:0004617|GO:0006564 KEGG: 00260+1.1.1.95|KEGG: 00680+1.1.1.95|Reactome: R-HSA-977347 A4G23_RS20135 2f9ed9494d40b6c1d2b712566c509d10 529 Gene3D G3DSA:3.40.50.720 3 108 2.1E-34 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS20135 2f9ed9494d40b6c1d2b712566c509d10 529 Gene3D G3DSA:3.30.70.260 447 524 1.8E-19 T 10-11-2016 A4G23_RS20135 2f9ed9494d40b6c1d2b712566c509d10 529 Gene3D G3DSA:3.40.50.720 109 284 5.1E-69 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS20135 2f9ed9494d40b6c1d2b712566c509d10 529 Gene3D G3DSA:3.30.1330.90 319 446 1.7E-42 T 10-11-2016 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 A4G23_RS20135 2f9ed9494d40b6c1d2b712566c509d10 529 SUPERFAMILY SSF55021 455 524 5.83E-16 T 10-11-2016 A4G23_RS20135 2f9ed9494d40b6c1d2b712566c509d10 529 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 222 238 - T 10-11-2016 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A4G23_RS20135 2f9ed9494d40b6c1d2b712566c509d10 529 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 7 314 3.5E-32 T 10-11-2016 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 A4G23_RS20135 2f9ed9494d40b6c1d2b712566c509d10 529 Pfam PF01842 ACT domain 455 516 1.2E-11 T 10-11-2016 IPR002912 ACT domain GO:0008152|GO:0016597 A4G23_RS02060 9344cc490a8ecec28e720198059950d2 267 Gene3D G3DSA:1.10.3720.10 5 254 5.8E-61 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS02060 9344cc490a8ecec28e720198059950d2 267 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 258 2.3E-22 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS02060 9344cc490a8ecec28e720198059950d2 267 SUPERFAMILY SSF161098 4 266 2.34E-65 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS20950 39ec5cac49d2a30578ba63002557a3d7 422 Gene3D G3DSA:3.40.50.200 45 344 1.9E-80 T 10-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4G23_RS20950 39ec5cac49d2a30578ba63002557a3d7 422 SUPERFAMILY SSF52743 53 345 1.1E-77 T 10-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4G23_RS20950 39ec5cac49d2a30578ba63002557a3d7 422 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 129 139 - T 10-11-2016 IPR022398 Peptidase S8, subtilisin, His-active site A4G23_RS20950 39ec5cac49d2a30578ba63002557a3d7 422 Pfam PF00082 Subtilase family 71 336 8.1E-47 T 10-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4G23_RS20950 39ec5cac49d2a30578ba63002557a3d7 422 PRINTS PR00723 Subtilisin serine protease family (S8) signature 71 90 6.4E-20 T 10-11-2016 IPR015500 Peptidase S8, subtilisin-related A4G23_RS20950 39ec5cac49d2a30578ba63002557a3d7 422 PRINTS PR00723 Subtilisin serine protease family (S8) signature 286 302 6.4E-20 T 10-11-2016 IPR015500 Peptidase S8, subtilisin-related A4G23_RS20950 39ec5cac49d2a30578ba63002557a3d7 422 PRINTS PR00723 Subtilisin serine protease family (S8) signature 125 138 6.4E-20 T 10-11-2016 IPR015500 Peptidase S8, subtilisin-related A4G23_RS20950 39ec5cac49d2a30578ba63002557a3d7 422 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 287 297 - T 10-11-2016 IPR023828 Peptidase S8, subtilisin, Ser-active site A4G23_RS20950 39ec5cac49d2a30578ba63002557a3d7 422 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 76 87 - T 10-11-2016 IPR023827 Peptidase S8, subtilisin, Asp-active site A4G23_RS20950 39ec5cac49d2a30578ba63002557a3d7 422 TIGRFAM TIGR03921 T7SS_mycosin: type VII secretion-associated serine protease mycosin 62 412 6.7E-99 T 10-11-2016 IPR023834 Type VII secretion system peptidase S8A, mycosin-1 A4G23_RS15655 9aa1c549b4103cb6f8b7e79f19746445 277 SMART SM00530 23 78 2.3E-8 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS15655 9aa1c549b4103cb6f8b7e79f19746445 277 SUPERFAMILY SSF47413 17 72 6.7E-9 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS15655 9aa1c549b4103cb6f8b7e79f19746445 277 Pfam PF13560 Helix-turn-helix domain 20 76 5.6E-11 T 10-11-2016 A4G23_RS15655 9aa1c549b4103cb6f8b7e79f19746445 277 Gene3D G3DSA:1.10.260.40 20 72 1.0E-9 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS13330 df61398bae2c9fdc70344092e208b2df 164 SMART SM00240 90 141 3.6E-13 T 10-11-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 A4G23_RS13330 df61398bae2c9fdc70344092e208b2df 164 Pfam PF00498 FHA domain 91 156 7.7E-16 T 10-11-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 A4G23_RS13330 df61398bae2c9fdc70344092e208b2df 164 SUPERFAMILY SSF49879 62 163 2.3E-28 T 10-11-2016 IPR008984 SMAD/FHA domain GO:0005515 A4G23_RS13330 df61398bae2c9fdc70344092e208b2df 164 Gene3D G3DSA:2.60.200.20 70 163 1.5E-27 T 10-11-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 A4G23_RS07035 9393c8fe7705149feee2720685a1ec23 540 Pfam PF09423 PhoD-like phosphatase 168 509 2.7E-107 T 10-11-2016 IPR018946 Alkaline phosphatase D-related A4G23_RS07035 9393c8fe7705149feee2720685a1ec23 540 SUPERFAMILY SSF56300 164 512 3.6E-28 T 10-11-2016 IPR029052 Metallo-dependent phosphatase-like A4G23_RS07035 9393c8fe7705149feee2720685a1ec23 540 Gene3D G3DSA:3.60.21.10 164 512 7.7E-11 T 10-11-2016 IPR029052 Metallo-dependent phosphatase-like A4G23_RS07035 9393c8fe7705149feee2720685a1ec23 540 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 58 154 2.3E-33 T 10-11-2016 IPR032093 Phospholipase D, N-terminal A4G23_RS17850 47a43466ddabd0732e1ae31bfc17eeb6 529 SUPERFAMILY SSF52096 14 265 3.89E-81 T 10-11-2016 IPR029045 ClpP/crotonase-like domain A4G23_RS17850 47a43466ddabd0732e1ae31bfc17eeb6 529 SUPERFAMILY SSF52096 276 529 2.61E-89 T 10-11-2016 IPR029045 ClpP/crotonase-like domain A4G23_RS17850 47a43466ddabd0732e1ae31bfc17eeb6 529 Gene3D G3DSA:3.90.226.10 8 265 8.8E-84 T 10-11-2016 IPR029045 ClpP/crotonase-like domain A4G23_RS17850 47a43466ddabd0732e1ae31bfc17eeb6 529 Gene3D G3DSA:3.90.226.10 276 529 4.5E-101 T 10-11-2016 IPR029045 ClpP/crotonase-like domain A4G23_RS17850 47a43466ddabd0732e1ae31bfc17eeb6 529 Pfam PF01039 Carboxyl transferase domain 37 527 2.7E-197 T 10-11-2016 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4G23_RS14590 dae847f614a8ea687dc8d66c05bcecb0 427 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 10-11-2016 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A4G23_RS14590 dae847f614a8ea687dc8d66c05bcecb0 427 Gene3D G3DSA:1.10.300.10 101 194 9.0E-34 T 10-11-2016 A4G23_RS14590 dae847f614a8ea687dc8d66c05bcecb0 427 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 427 200.034 T 10-11-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A4G23_RS14590 dae847f614a8ea687dc8d66c05bcecb0 427 Gene3D G3DSA:3.40.440.10 195 264 3.4E-71 T 10-11-2016 A4G23_RS14590 dae847f614a8ea687dc8d66c05bcecb0 427 Gene3D G3DSA:3.40.440.10 4 93 3.4E-71 T 10-11-2016 A4G23_RS14590 dae847f614a8ea687dc8d66c05bcecb0 427 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 131 142 - T 10-11-2016 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A4G23_RS14590 dae847f614a8ea687dc8d66c05bcecb0 427 SUPERFAMILY SSF52540 3 425 4.57E-173 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS14590 dae847f614a8ea687dc8d66c05bcecb0 427 Pfam PF00709 Adenylosuccinate synthetase 5 421 2.8E-177 T 10-11-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A4G23_RS14590 dae847f614a8ea687dc8d66c05bcecb0 427 SMART SM00788 3 422 2.8E-286 T 10-11-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A4G23_RS14590 dae847f614a8ea687dc8d66c05bcecb0 427 Gene3D G3DSA:3.90.170.10 266 422 1.0E-67 T 10-11-2016 A4G23_RS14590 dae847f614a8ea687dc8d66c05bcecb0 427 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 423 4.0E-167 T 10-11-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A4G23_RS17080 d7ede69a97903cb5e3f6d51da92ea70b 428 SUPERFAMILY SSF55874 302 420 3.01E-12 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS17080 d7ede69a97903cb5e3f6d51da92ea70b 428 Pfam PF04024 PspC domain 17 73 1.4E-15 T 10-11-2016 IPR007168 Phage shock protein, PspC, N-terminal A4G23_RS17080 d7ede69a97903cb5e3f6d51da92ea70b 428 Pfam PF13581 Histidine kinase-like ATPase domain 294 385 2.0E-7 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS17080 d7ede69a97903cb5e3f6d51da92ea70b 428 Gene3D G3DSA:3.30.565.10 311 424 6.2E-9 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS02210 ae3d11980f3037a7eeae1ec237412d01 336 Gene3D G3DSA:3.40.50.2300 172 311 5.9E-47 T 10-11-2016 A4G23_RS02210 ae3d11980f3037a7eeae1ec237412d01 336 Gene3D G3DSA:1.10.260.40 1 50 2.0E-23 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS02210 ae3d11980f3037a7eeae1ec237412d01 336 SMART SM00354 1 68 2.6E-21 T 10-11-2016 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4G23_RS02210 ae3d11980f3037a7eeae1ec237412d01 336 Gene3D G3DSA:3.40.50.2300 51 171 5.4E-24 T 10-11-2016 A4G23_RS02210 ae3d11980f3037a7eeae1ec237412d01 336 Pfam PF00356 Bacterial regulatory proteins, lacI family 1 45 3.4E-16 T 10-11-2016 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4G23_RS02210 ae3d11980f3037a7eeae1ec237412d01 336 ProSitePatterns PS00356 LacI-type HTH domain signature. 1 19 - T 10-11-2016 A4G23_RS02210 ae3d11980f3037a7eeae1ec237412d01 336 SUPERFAMILY SSF47413 1 56 1.37E-15 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS02210 ae3d11980f3037a7eeae1ec237412d01 336 Pfam PF13377 Periplasmic binding protein-like domain 165 330 6.1E-36 T 10-11-2016 A4G23_RS02210 ae3d11980f3037a7eeae1ec237412d01 336 SUPERFAMILY SSF53822 57 333 3.26E-54 T 10-11-2016 IPR028082 Periplasmic binding protein-like I A4G23_RS24445 8e3adcde8ce0009953df7a067adeb3e5 458 Gene3D G3DSA:3.30.450.20 69 179 3.7E-14 T 10-11-2016 A4G23_RS24445 8e3adcde8ce0009953df7a067adeb3e5 458 SUPERFAMILY SSF55781 329 436 8.24E-6 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS24445 8e3adcde8ce0009953df7a067adeb3e5 458 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 70 147 2.1E-6 T 10-11-2016 IPR000014 PAS domain A4G23_RS24445 8e3adcde8ce0009953df7a067adeb3e5 458 SMART SM00091 73 139 9.4E-7 T 10-11-2016 IPR000014 PAS domain A4G23_RS24445 8e3adcde8ce0009953df7a067adeb3e5 458 Gene3D G3DSA:3.30.450.40 276 436 1.5E-9 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS24445 8e3adcde8ce0009953df7a067adeb3e5 458 Pfam PF08448 PAS fold 80 178 2.5E-11 T 10-11-2016 IPR013656 PAS fold-4 A4G23_RS24445 8e3adcde8ce0009953df7a067adeb3e5 458 SUPERFAMILY SSF55785 68 169 1.08E-13 T 10-11-2016 IPR000014 PAS domain A4G23_RS20120 b0d83efd4b6aa7a1e3a6ab70b78a9204 617 SUPERFAMILY SSF52518 27 207 2.95E-59 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS20120 b0d83efd4b6aa7a1e3a6ab70b78a9204 617 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 29 194 2.1E-54 T 10-11-2016 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 A4G23_RS20120 b0d83efd4b6aa7a1e3a6ab70b78a9204 617 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 454 473 - T 10-11-2016 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 A4G23_RS20120 b0d83efd4b6aa7a1e3a6ab70b78a9204 617 SUPERFAMILY SSF52518 394 606 1.97E-68 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS20120 b0d83efd4b6aa7a1e3a6ab70b78a9204 617 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 218 353 3.2E-47 T 10-11-2016 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 A4G23_RS20120 b0d83efd4b6aa7a1e3a6ab70b78a9204 617 SUPERFAMILY SSF52467 210 385 3.66E-62 T 10-11-2016 IPR029035 DHS-like NAD/FAD-binding domain A4G23_RS20120 b0d83efd4b6aa7a1e3a6ab70b78a9204 617 Gene3D G3DSA:3.40.50.970 27 204 1.3E-70 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS20120 b0d83efd4b6aa7a1e3a6ab70b78a9204 617 Gene3D G3DSA:3.40.50.1220 213 377 3.5E-67 T 10-11-2016 IPR029035 DHS-like NAD/FAD-binding domain A4G23_RS20120 b0d83efd4b6aa7a1e3a6ab70b78a9204 617 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 29 603 2.4E-232 T 10-11-2016 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 A4G23_RS20120 b0d83efd4b6aa7a1e3a6ab70b78a9204 617 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 417 580 1.2E-48 T 10-11-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A4G23_RS20120 b0d83efd4b6aa7a1e3a6ab70b78a9204 617 Gene3D G3DSA:3.40.50.970 378 595 3.7E-78 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS22230 d1f3befba205e328ee047f587d555f90 138 SUPERFAMILY SSF103247 2 126 6.28E-35 T 10-11-2016 IPR005180 Domain of unknown function DUF302 A4G23_RS22230 d1f3befba205e328ee047f587d555f90 138 Pfam PF03625 Domain of unknown function DUF302 35 97 4.3E-24 T 10-11-2016 IPR005180 Domain of unknown function DUF302 A4G23_RS22230 d1f3befba205e328ee047f587d555f90 138 Gene3D G3DSA:3.30.310.70 3 126 3.0E-47 T 10-11-2016 IPR005180 Domain of unknown function DUF302 A4G23_RS22230 d1f3befba205e328ee047f587d555f90 138 PIRSF PIRSF021774 1 129 1.4E-42 T 10-11-2016 IPR016796 Uncharacterised conserved protein UCP021774 A4G23_RS14755 845c741c279e0bc94bee4cb0c9d0fc66 646 Gene3D G3DSA:3.40.50.1820 374 635 4.0E-75 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS14755 845c741c279e0bc94bee4cb0c9d0fc66 646 Gene3D G3DSA:3.40.50.1820 82 121 4.0E-75 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS14755 845c741c279e0bc94bee4cb0c9d0fc66 646 Gene3D G3DSA:2.120.10.30 184 349 2.7E-16 T 10-11-2016 IPR011042 Six-bladed beta-propeller, TolB-like A4G23_RS14755 845c741c279e0bc94bee4cb0c9d0fc66 646 SUPERFAMILY SSF53474 385 635 2.18E-55 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS14755 845c741c279e0bc94bee4cb0c9d0fc66 646 Pfam PF00326 Prolyl oligopeptidase family 434 635 1.8E-41 T 10-11-2016 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 A4G23_RS14755 845c741c279e0bc94bee4cb0c9d0fc66 646 SUPERFAMILY SSF82171 74 363 1.37E-23 T 10-11-2016 A4G23_RS17250 fcece167130426fdb88fc04bc31734f5 388 SUPERFAMILY SSF47413 22 87 3.13E-5 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS17250 fcece167130426fdb88fc04bc31734f5 388 SMART SM00530 21 76 0.0031 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS17250 fcece167130426fdb88fc04bc31734f5 388 Pfam PF13560 Helix-turn-helix domain 19 76 1.8E-9 T 10-11-2016 A4G23_RS17250 fcece167130426fdb88fc04bc31734f5 388 Pfam PF10901 Protein of unknown function (DUF2690) 284 374 1.8E-17 T 10-11-2016 IPR021224 Protein of unknown function DUF2690 A4G23_RS17250 fcece167130426fdb88fc04bc31734f5 388 Gene3D G3DSA:1.10.260.40 15 78 3.0E-4 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS18710 9e77302cd7acba6190bc6550b2f8a44f 392 Gene3D G3DSA:3.40.50.720 12 258 6.3E-81 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS18710 9e77302cd7acba6190bc6550b2f8a44f 392 Pfam PF00581 Rhodanese-like domain 290 383 1.4E-12 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS18710 9e77302cd7acba6190bc6550b2f8a44f 392 Gene3D G3DSA:3.40.250.10 274 387 1.3E-26 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS18710 9e77302cd7acba6190bc6550b2f8a44f 392 SUPERFAMILY SSF69572 8 357 3.14E-107 T 10-11-2016 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 A4G23_RS18710 9e77302cd7acba6190bc6550b2f8a44f 392 Pfam PF00899 ThiF family 21 254 7.0E-68 T 10-11-2016 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 A4G23_RS18710 9e77302cd7acba6190bc6550b2f8a44f 392 SMART SM00450 290 387 2.8E-22 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS25070 a5a2afb742554483d6e9e3d57e998856 383 SUPERFAMILY SSF46955 1 67 3.48E-12 T 10-11-2016 IPR009061 Putative DNA-binding domain A4G23_RS25070 a5a2afb742554483d6e9e3d57e998856 383 Gene3D G3DSA:3.40.50.280 263 317 2.5E-6 T 10-11-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A4G23_RS25070 a5a2afb742554483d6e9e3d57e998856 383 SUPERFAMILY SSF52242 260 318 5.02E-8 T 10-11-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A4G23_RS25070 a5a2afb742554483d6e9e3d57e998856 383 Pfam PF02310 B12 binding domain 263 350 6.6E-9 T 10-11-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A4G23_RS25070 a5a2afb742554483d6e9e3d57e998856 383 Pfam PF13411 MerR HTH family regulatory protein 1 66 8.8E-12 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS25070 a5a2afb742554483d6e9e3d57e998856 383 Gene3D G3DSA:1.10.1660.10 1 73 5.3E-13 T 10-11-2016 A4G23_RS25070 a5a2afb742554483d6e9e3d57e998856 383 SMART SM00422 1 70 3.8E-8 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS25070 a5a2afb742554483d6e9e3d57e998856 383 Pfam PF02607 B12 binding domain 173 243 3.6E-10 T 10-11-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4G23_RS10115 0b681bf614701bd95722ac85b42a60cc 430 Gene3D G3DSA:1.10.287.130 193 263 3.2E-11 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS10115 0b681bf614701bd95722ac85b42a60cc 430 SMART SM00387 309 410 2.2E-13 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS10115 0b681bf614701bd95722ac85b42a60cc 430 SUPERFAMILY SSF55874 270 406 3.27E-23 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS10115 0b681bf614701bd95722ac85b42a60cc 430 Pfam PF00672 HAMP domain 130 197 1.2E-9 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS10115 0b681bf614701bd95722ac85b42a60cc 430 Pfam PF00512 His Kinase A (phospho-acceptor) domain 203 263 1.0E-7 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS10115 0b681bf614701bd95722ac85b42a60cc 430 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 312 394 3.6E-8 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS10115 0b681bf614701bd95722ac85b42a60cc 430 PRINTS PR00344 Bacterial sensor protein C-terminal signature 362 372 1.3E-8 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS10115 0b681bf614701bd95722ac85b42a60cc 430 PRINTS PR00344 Bacterial sensor protein C-terminal signature 372 390 1.3E-8 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS10115 0b681bf614701bd95722ac85b42a60cc 430 PRINTS PR00344 Bacterial sensor protein C-terminal signature 344 358 1.3E-8 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS10115 0b681bf614701bd95722ac85b42a60cc 430 SMART SM00388 202 267 1.5E-7 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS10115 0b681bf614701bd95722ac85b42a60cc 430 Gene3D G3DSA:3.30.565.10 271 396 4.9E-24 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS10115 0b681bf614701bd95722ac85b42a60cc 430 SUPERFAMILY SSF47384 186 263 5.1E-12 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS23585 feea57a5caf0503244aaa0345d5b43d5 234 Pfam PF00702 haloacid dehalogenase-like hydrolase 18 222 6.6E-17 T 10-11-2016 A4G23_RS23585 feea57a5caf0503244aaa0345d5b43d5 234 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 113 227 2.1E-14 T 10-11-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A4G23_RS23585 feea57a5caf0503244aaa0345d5b43d5 234 Gene3D G3DSA:3.40.50.1000 13 31 4.2E-31 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS23585 feea57a5caf0503244aaa0345d5b43d5 234 Gene3D G3DSA:3.40.50.1000 130 229 4.2E-31 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS23585 feea57a5caf0503244aaa0345d5b43d5 234 SUPERFAMILY SSF56784 18 231 1.62E-39 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS02645 1a2d60cef377b5be1ed7f320176897ea 333 Gene3D G3DSA:3.40.50.300 107 224 4.8E-5 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS02645 1a2d60cef377b5be1ed7f320176897ea 333 SUPERFAMILY SSF52540 106 247 2.85E-7 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS02645 1a2d60cef377b5be1ed7f320176897ea 333 Pfam PF13401 AAA domain 113 220 1.3E-11 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS18025 8247bb59c48adc8743e0db6c7f6c4739 607 Pfam PF00821 Phosphoenolpyruvate carboxykinase 21 606 4.2E-285 T 10-11-2016 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 A4G23_RS18025 8247bb59c48adc8743e0db6c7f6c4739 607 SUPERFAMILY SSF53795 247 606 9.39E-162 T 10-11-2016 A4G23_RS18025 8247bb59c48adc8743e0db6c7f6c4739 607 ProSitePatterns PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 271 279 - T 10-11-2016 IPR018091 Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site GO:0004613 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 A4G23_RS18025 8247bb59c48adc8743e0db6c7f6c4739 607 SUPERFAMILY SSF68923 11 246 2.56E-96 T 10-11-2016 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 A4G23_RS18025 8247bb59c48adc8743e0db6c7f6c4739 607 PIRSF PIRSF001348 2 607 1.7E-281 T 10-11-2016 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 A4G23_RS18025 8247bb59c48adc8743e0db6c7f6c4739 607 Gene3D G3DSA:3.40.449.10 10 246 2.7E-99 T 10-11-2016 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 A4G23_RS18025 8247bb59c48adc8743e0db6c7f6c4739 607 Gene3D G3DSA:3.90.228.20 333 606 4.7E-104 T 10-11-2016 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 A4G23_RS18025 8247bb59c48adc8743e0db6c7f6c4739 607 Gene3D G3DSA:3.90.228.20 247 316 2.4E-33 T 10-11-2016 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 A4G23_RS18025 8247bb59c48adc8743e0db6c7f6c4739 607 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 9 607 52.644 T 10-11-2016 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 A4G23_RS03850 d51b8da08a1208b017286c87aa12b2f5 267 Gene3D G3DSA:3.40.630.30 152 258 3.9E-21 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS03850 d51b8da08a1208b017286c87aa12b2f5 267 SUPERFAMILY SSF55729 155 258 1.05E-20 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS03850 d51b8da08a1208b017286c87aa12b2f5 267 Gene3D G3DSA:3.40.630.30 25 110 5.7E-12 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS03850 d51b8da08a1208b017286c87aa12b2f5 267 Pfam PF00583 Acetyltransferase (GNAT) family 27 104 9.9E-8 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS03850 d51b8da08a1208b017286c87aa12b2f5 267 Pfam PF00583 Acetyltransferase (GNAT) family 176 256 7.5E-15 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS03850 d51b8da08a1208b017286c87aa12b2f5 267 SUPERFAMILY SSF55729 20 112 1.61E-12 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS02085 b396c70401a67727ad7e2f2d112b2609 229 SUPERFAMILY SSF56784 2 192 2.31E-54 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS02085 b396c70401a67727ad7e2f2d112b2609 229 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 51 184 4.4E-18 T 10-11-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A4G23_RS02085 b396c70401a67727ad7e2f2d112b2609 229 Gene3D G3DSA:3.40.50.1000 1 15 7.6E-44 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS02085 b396c70401a67727ad7e2f2d112b2609 229 Gene3D G3DSA:3.40.50.1000 88 188 7.6E-44 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS02085 b396c70401a67727ad7e2f2d112b2609 229 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 128 144 6.9E-9 T 10-11-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A4G23_RS02085 b396c70401a67727ad7e2f2d112b2609 229 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 97 110 6.9E-9 T 10-11-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A4G23_RS02085 b396c70401a67727ad7e2f2d112b2609 229 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 146 166 6.9E-9 T 10-11-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A4G23_RS02085 b396c70401a67727ad7e2f2d112b2609 229 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 1 12 6.9E-9 T 10-11-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A4G23_RS02085 b396c70401a67727ad7e2f2d112b2609 229 Pfam PF13419 Haloacid dehalogenase-like hydrolase 4 184 1.0E-31 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS14170 4815bb239ff8a4d636d6fa73c1c193db 312 SUPERFAMILY SSF54427 193 305 3.66E-15 T 10-11-2016 IPR032710 NTF2-like domain A4G23_RS14170 4815bb239ff8a4d636d6fa73c1c193db 312 Gene3D G3DSA:1.10.10.10 132 184 3.1E-8 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS14170 4815bb239ff8a4d636d6fa73c1c193db 312 Gene3D G3DSA:1.10.1740.10 8 84 1.3E-4 T 10-11-2016 A4G23_RS14170 4815bb239ff8a4d636d6fa73c1c193db 312 SUPERFAMILY SSF88946 7 90 9.81E-5 T 10-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS14170 4815bb239ff8a4d636d6fa73c1c193db 312 Pfam PF08281 Sigma-70, region 4 132 179 1.1E-6 T 10-11-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS14170 4815bb239ff8a4d636d6fa73c1c193db 312 Pfam PF04542 Sigma-70 region 2 11 81 2.8E-5 T 10-11-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS14170 4815bb239ff8a4d636d6fa73c1c193db 312 Gene3D G3DSA:3.10.450.50 192 304 1.2E-11 T 10-11-2016 IPR032710 NTF2-like domain A4G23_RS14170 4815bb239ff8a4d636d6fa73c1c193db 312 SUPERFAMILY SSF88659 131 184 6.92E-8 T 10-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS17425 f03f7139692690100834a0c9562bed88 511 Pfam PF13535 ATP-grasp domain 149 295 2.5E-17 T 10-11-2016 A4G23_RS17425 f03f7139692690100834a0c9562bed88 511 SUPERFAMILY SSF56059 107 333 6.54E-34 T 10-11-2016 A4G23_RS17425 f03f7139692690100834a0c9562bed88 511 Gene3D G3DSA:3.30.470.20 108 328 1.9E-25 T 10-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 A4G23_RS17425 f03f7139692690100834a0c9562bed88 511 SMART SM01209 114 293 2.9E-5 T 10-11-2016 A4G23_RS21255 61efe398bd3fc0848fbcddb4bcca1c6e 290 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 6 282 30.972 T 10-11-2016 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 A4G23_RS21255 61efe398bd3fc0848fbcddb4bcca1c6e 290 Gene3D G3DSA:3.10.310.10 133 270 9.4E-39 T 10-11-2016 A4G23_RS21255 61efe398bd3fc0848fbcddb4bcca1c6e 290 SUPERFAMILY SSF54506 142 281 1.71E-35 T 10-11-2016 A4G23_RS21255 61efe398bd3fc0848fbcddb4bcca1c6e 290 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 7 280 2.9E-66 T 10-11-2016 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 A4G23_RS21255 61efe398bd3fc0848fbcddb4bcca1c6e 290 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 77 91 - T 10-11-2016 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 A4G23_RS21255 61efe398bd3fc0848fbcddb4bcca1c6e 290 Gene3D G3DSA:3.10.310.10 7 132 2.2E-40 T 10-11-2016 A4G23_RS21255 61efe398bd3fc0848fbcddb4bcca1c6e 290 Pfam PF01678 Diaminopimelate epimerase 154 275 3.3E-27 T 10-11-2016 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 A4G23_RS21255 61efe398bd3fc0848fbcddb4bcca1c6e 290 Pfam PF01678 Diaminopimelate epimerase 8 136 1.1E-35 T 10-11-2016 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 A4G23_RS21255 61efe398bd3fc0848fbcddb4bcca1c6e 290 SUPERFAMILY SSF54506 6 136 1.65E-33 T 10-11-2016 A4G23_RS05045 5e101f61b35888f80fe7f070bd533fc4 311 ProSitePatterns PS01270 Band 7 protein family signature. 135 163 - T 10-11-2016 IPR018080 Band 7/stomatin-like, conserved site A4G23_RS05045 5e101f61b35888f80fe7f070bd533fc4 311 SUPERFAMILY SSF117892 52 186 1.96E-39 T 10-11-2016 IPR001107 Band 7 domain A4G23_RS05045 5e101f61b35888f80fe7f070bd533fc4 311 Pfam PF01145 SPFH domain / Band 7 family 25 194 5.8E-34 T 10-11-2016 IPR001107 Band 7 domain A4G23_RS05045 5e101f61b35888f80fe7f070bd533fc4 311 SMART SM00244 21 179 1.7E-52 T 10-11-2016 IPR001107 Band 7 domain A4G23_RS05045 5e101f61b35888f80fe7f070bd533fc4 311 PRINTS PR00721 Stomatin signature 111 128 1.3E-31 T 10-11-2016 IPR001972 Stomatin family GO:0016020 A4G23_RS05045 5e101f61b35888f80fe7f070bd533fc4 311 PRINTS PR00721 Stomatin signature 155 173 1.3E-31 T 10-11-2016 IPR001972 Stomatin family GO:0016020 A4G23_RS05045 5e101f61b35888f80fe7f070bd533fc4 311 PRINTS PR00721 Stomatin signature 76 97 1.3E-31 T 10-11-2016 IPR001972 Stomatin family GO:0016020 A4G23_RS05045 5e101f61b35888f80fe7f070bd533fc4 311 PRINTS PR00721 Stomatin signature 174 195 1.3E-31 T 10-11-2016 IPR001972 Stomatin family GO:0016020 A4G23_RS05045 5e101f61b35888f80fe7f070bd533fc4 311 PRINTS PR00721 Stomatin signature 28 50 1.3E-31 T 10-11-2016 IPR001972 Stomatin family GO:0016020 A4G23_RS05045 5e101f61b35888f80fe7f070bd533fc4 311 PRINTS PR00721 Stomatin signature 131 154 1.3E-31 T 10-11-2016 IPR001972 Stomatin family GO:0016020 A4G23_RS12215 8699328153ecc2fee23be1cadd1a22ff 226 SUPERFAMILY SSF109755 2 215 1.99E-58 T 10-11-2016 A4G23_RS12215 8699328153ecc2fee23be1cadd1a22ff 226 Gene3D G3DSA:1.20.58.220 1 105 3.1E-28 T 10-11-2016 A4G23_RS12215 8699328153ecc2fee23be1cadd1a22ff 226 PIRSF PIRSF003107 1 217 6.2E-55 T 10-11-2016 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 A4G23_RS12215 8699328153ecc2fee23be1cadd1a22ff 226 Pfam PF01895 PhoU domain 16 103 3.3E-17 T 10-11-2016 IPR026022 PhoU domain A4G23_RS12215 8699328153ecc2fee23be1cadd1a22ff 226 Pfam PF01895 PhoU domain 121 204 1.2E-13 T 10-11-2016 IPR026022 PhoU domain A4G23_RS12215 8699328153ecc2fee23be1cadd1a22ff 226 Gene3D G3DSA:1.20.58.220 116 216 7.6E-22 T 10-11-2016 A4G23_RS12215 8699328153ecc2fee23be1cadd1a22ff 226 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 4 212 2.0E-57 T 10-11-2016 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 A4G23_RS04420 5ad13eb9936ded4e7fcafb363aee8837 261 Gene3D G3DSA:1.20.1260.10 47 168 1.4E-4 T 10-11-2016 IPR012347 Ferritin-related A4G23_RS04420 5ad13eb9936ded4e7fcafb363aee8837 261 SUPERFAMILY SSF47240 15 165 4.43E-7 T 10-11-2016 IPR009078 Ferritin-like superfamily A4G23_RS17860 e6ed53bb6136e24ed7c94335d2b339a6 379 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 189 318 3.9E-14 T 10-11-2016 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 A4G23_RS17860 e6ed53bb6136e24ed7c94335d2b339a6 379 Gene3D G3DSA:3.30.70.1230 188 332 7.3E-21 T 10-11-2016 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 A4G23_RS17860 e6ed53bb6136e24ed7c94335d2b339a6 379 Pfam PF16701 Adenylate cyclase regulatory domain 37 160 3.9E-8 T 10-11-2016 IPR032026 Adenylate cyclase regulatory domain A4G23_RS17860 e6ed53bb6136e24ed7c94335d2b339a6 379 SUPERFAMILY SSF55073 187 321 9.26E-33 T 10-11-2016 IPR029787 Nucleotide cyclase A4G23_RS17860 e6ed53bb6136e24ed7c94335d2b339a6 379 SMART SM00044 74 327 1.7E-4 T 10-11-2016 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 A4G23_RS06420 acb75de33d95ecbc10ace983953e3e05 224 Gene3D G3DSA:3.40.50.2300 2 122 2.8E-31 T 10-11-2016 A4G23_RS06420 acb75de33d95ecbc10ace983953e3e05 224 Pfam PF00072 Response regulator receiver domain 8 120 2.8E-24 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS06420 acb75de33d95ecbc10ace983953e3e05 224 SMART SM00448 6 119 2.3E-32 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS06420 acb75de33d95ecbc10ace983953e3e05 224 ProSitePatterns PS00622 LuxR-type HTH domain signature. 176 203 - T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS06420 acb75de33d95ecbc10ace983953e3e05 224 SUPERFAMILY SSF46894 150 221 1.63E-23 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS06420 acb75de33d95ecbc10ace983953e3e05 224 SMART SM00421 159 216 1.0E-26 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS06420 acb75de33d95ecbc10ace983953e3e05 224 Pfam PF00196 Bacterial regulatory proteins, luxR family 161 216 2.0E-20 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS06420 acb75de33d95ecbc10ace983953e3e05 224 SUPERFAMILY SSF52172 5 125 1.99E-31 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS06420 acb75de33d95ecbc10ace983953e3e05 224 Gene3D G3DSA:1.10.10.10 123 221 7.1E-32 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS06420 acb75de33d95ecbc10ace983953e3e05 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 176 1.1E-13 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS06420 acb75de33d95ecbc10ace983953e3e05 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 192 204 1.1E-13 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS06420 acb75de33d95ecbc10ace983953e3e05 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 192 1.1E-13 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS08730 0b33244083c18ea38791df7708656779 500 Gene3D G3DSA:3.40.605.10 4 261 1.3E-91 T 10-11-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A4G23_RS08730 0b33244083c18ea38791df7708656779 500 SUPERFAMILY SSF53720 2 484 1.31E-150 T 10-11-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A4G23_RS08730 0b33244083c18ea38791df7708656779 500 Pfam PF00171 Aldehyde dehydrogenase family 18 478 1.3E-139 T 10-11-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A4G23_RS08730 0b33244083c18ea38791df7708656779 500 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 275 286 - T 10-11-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 A4G23_RS08730 0b33244083c18ea38791df7708656779 500 Gene3D G3DSA:3.40.309.10 262 443 9.8E-63 T 10-11-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 A4G23_RS08730 0b33244083c18ea38791df7708656779 500 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 5 482 1.3E-249 T 10-11-2016 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373|Reactome: R-HSA-70895 A4G23_RS17465 b108cec952ecb799b11e23541bc84927 305 SUPERFAMILY SSF51569 4 295 1.67E-45 T 10-11-2016 A4G23_RS17465 b108cec952ecb799b11e23541bc84927 305 SMART SM01130 4 297 5.2E-36 T 10-11-2016 IPR002220 DapA-like GO:0008152|GO:0016829 A4G23_RS17465 b108cec952ecb799b11e23541bc84927 305 PIRSF PIRSF001365 1 304 4.1E-33 T 10-11-2016 IPR002220 DapA-like GO:0008152|GO:0016829 A4G23_RS17465 b108cec952ecb799b11e23541bc84927 305 Gene3D G3DSA:3.20.20.70 2 303 3.8E-47 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS17465 b108cec952ecb799b11e23541bc84927 305 Pfam PF00701 Dihydrodipicolinate synthetase family 6 292 5.7E-29 T 10-11-2016 IPR002220 DapA-like GO:0008152|GO:0016829 A4G23_RS11800 db60976b6a089218cfd2a2c77531ed4e 547 Pfam PF16203 ERCC3/RAD25/XPB C-terminal helicase 352 541 7.3E-48 T 10-11-2016 IPR032438 ERCC3/RAD25/XPB helicase, C-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 A4G23_RS11800 db60976b6a089218cfd2a2c77531ed4e 547 SMART SM00487 177 352 1.6E-20 T 10-11-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4G23_RS11800 db60976b6a089218cfd2a2c77531ed4e 547 SUPERFAMILY SSF52540 289 359 5.85E-29 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS11800 db60976b6a089218cfd2a2c77531ed4e 547 SUPERFAMILY SSF52540 392 510 5.85E-29 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS11800 db60976b6a089218cfd2a2c77531ed4e 547 Pfam PF04851 Type III restriction enzyme, res subunit 181 325 3.0E-12 T 10-11-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 A4G23_RS11800 db60976b6a089218cfd2a2c77531ed4e 547 SUPERFAMILY SSF52540 142 342 1.29E-32 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS11800 db60976b6a089218cfd2a2c77531ed4e 547 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 474 499 2.1E-36 T 10-11-2016 A4G23_RS11800 db60976b6a089218cfd2a2c77531ed4e 547 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 290 310 2.1E-36 T 10-11-2016 A4G23_RS11800 db60976b6a089218cfd2a2c77531ed4e 547 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 455 473 2.1E-36 T 10-11-2016 A4G23_RS11800 db60976b6a089218cfd2a2c77531ed4e 547 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 409 431 2.1E-36 T 10-11-2016 A4G23_RS11800 db60976b6a089218cfd2a2c77531ed4e 547 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 355 377 2.1E-36 T 10-11-2016 A4G23_RS11800 db60976b6a089218cfd2a2c77531ed4e 547 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 190 212 2.1E-36 T 10-11-2016 A4G23_RS11800 db60976b6a089218cfd2a2c77531ed4e 547 Gene3D G3DSA:3.40.50.300 180 342 1.7E-27 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS11800 db60976b6a089218cfd2a2c77531ed4e 547 SMART SM00490 422 499 5.4E-13 T 10-11-2016 IPR001650 Helicase, C-terminal A4G23_RS11800 db60976b6a089218cfd2a2c77531ed4e 547 Gene3D G3DSA:3.40.50.300 379 525 1.8E-15 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS11800 db60976b6a089218cfd2a2c77531ed4e 547 Pfam PF13625 Helicase conserved C-terminal domain 5 133 4.1E-46 T 10-11-2016 IPR032830 Helicase XPB/Ssl2, N-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 A4G23_RS03545 79a35967a29ab17e14ff96e2a894a530 1102 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1086 13.03 T 10-11-2016 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 A4G23_RS03545 79a35967a29ab17e14ff96e2a894a530 1102 SMART SM01096 426 547 4.4E-65 T 10-11-2016 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 A4G23_RS03545 79a35967a29ab17e14ff96e2a894a530 1102 SUPERFAMILY SSF52335 960 1094 1.44E-33 T 10-11-2016 IPR011607 Methylglyoxal synthase-like domain A4G23_RS03545 79a35967a29ab17e14ff96e2a894a530 1102 Pfam PF02142 MGS-like domain 975 1065 3.1E-21 T 10-11-2016 IPR011607 Methylglyoxal synthase-like domain A4G23_RS03545 79a35967a29ab17e14ff96e2a894a530 1102 Gene3D G3DSA:3.40.50.1380 957 1096 1.9E-40 T 10-11-2016 IPR011607 Methylglyoxal synthase-like domain A4G23_RS03545 79a35967a29ab17e14ff96e2a894a530 1102 SUPERFAMILY SSF48108 401 554 1.83E-48 T 10-11-2016 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 A4G23_RS03545 79a35967a29ab17e14ff96e2a894a530 1102 SUPERFAMILY SSF52440 2 127 3.74E-47 T 10-11-2016 IPR016185 Pre-ATP-grasp domain A4G23_RS03545 79a35967a29ab17e14ff96e2a894a530 1102 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 713 727 - T 10-11-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A4G23_RS03545 79a35967a29ab17e14ff96e2a894a530 1102 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 431 547 6.6E-39 T 10-11-2016 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 A4G23_RS03545 79a35967a29ab17e14ff96e2a894a530 1102 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 245 262 2.2E-63 T 10-11-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 A4G23_RS03545 79a35967a29ab17e14ff96e2a894a530 1102 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 303 332 2.2E-63 T 10-11-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 A4G23_RS03545 79a35967a29ab17e14ff96e2a894a530 1102 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 2.2E-63 T 10-11-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 A4G23_RS03545 79a35967a29ab17e14ff96e2a894a530 1102 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 385 403 2.2E-63 T 10-11-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 A4G23_RS03545 79a35967a29ab17e14ff96e2a894a530 1102 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 174 186 2.2E-63 T 10-11-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 A4G23_RS03545 79a35967a29ab17e14ff96e2a894a530 1102 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 210 229 2.2E-63 T 10-11-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 A4G23_RS03545 79a35967a29ab17e14ff96e2a894a530 1102 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 2.2E-63 T 10-11-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 A4G23_RS03545 79a35967a29ab17e14ff96e2a894a530 1102 Gene3D G3DSA:3.30.1490.20 690 748 1.1E-25 T 10-11-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A4G23_RS03545 79a35967a29ab17e14ff96e2a894a530 1102 Gene3D G3DSA:3.30.1490.20 149 205 6.4E-19 T 10-11-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A4G23_RS03545 79a35967a29ab17e14ff96e2a894a530 1102 Gene3D G3DSA:3.40.50.20 3 108 1.2E-42 T 10-11-2016 IPR016185 Pre-ATP-grasp domain A4G23_RS03545 79a35967a29ab17e14ff96e2a894a530 1102 Gene3D G3DSA:3.30.470.20 749 952 5.6E-62 T 10-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 A4G23_RS03545 79a35967a29ab17e14ff96e2a894a530 1102 Gene3D G3DSA:3.30.470.20 206 405 7.5E-78 T 10-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 A4G23_RS03545 79a35967a29ab17e14ff96e2a894a530 1102 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 842 849 - T 10-11-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A4G23_RS03545 79a35967a29ab17e14ff96e2a894a530 1102 Gene3D G3DSA:3.40.50.20 539 665 4.6E-56 T 10-11-2016 IPR016185 Pre-ATP-grasp domain A4G23_RS03545 79a35967a29ab17e14ff96e2a894a530 1102 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 677 879 6.4E-34 T 10-11-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A4G23_RS03545 79a35967a29ab17e14ff96e2a894a530 1102 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 340 6.2E-66 T 10-11-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A4G23_RS03545 79a35967a29ab17e14ff96e2a894a530 1102 SUPERFAMILY SSF52440 558 678 1.73E-42 T 10-11-2016 IPR016185 Pre-ATP-grasp domain A4G23_RS03545 79a35967a29ab17e14ff96e2a894a530 1102 SUPERFAMILY SSF56059 128 406 6.72E-101 T 10-11-2016 A4G23_RS03545 79a35967a29ab17e14ff96e2a894a530 1102 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1074 0.0 T 10-11-2016 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 A4G23_RS03545 79a35967a29ab17e14ff96e2a894a530 1102 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 303 310 - T 10-11-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A4G23_RS03545 79a35967a29ab17e14ff96e2a894a530 1102 Gene3D G3DSA:1.10.1030.10 406 538 1.7E-47 T 10-11-2016 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 A4G23_RS03545 79a35967a29ab17e14ff96e2a894a530 1102 SUPERFAMILY SSF56059 677 951 1.13E-89 T 10-11-2016 A4G23_RS03545 79a35967a29ab17e14ff96e2a894a530 1102 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 170 184 - T 10-11-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A4G23_RS03545 79a35967a29ab17e14ff96e2a894a530 1102 SMART SM00851 974 1065 4.1E-28 T 10-11-2016 IPR011607 Methylglyoxal synthase-like domain A4G23_RS05180 916cf93893328eb866b32943b324bb5e 329 Pfam PF06463 Molybdenum Cofactor Synthesis C 183 309 1.0E-36 T 10-11-2016 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4G23_RS05180 916cf93893328eb866b32943b324bb5e 329 Pfam PF04055 Radical SAM superfamily 16 177 2.6E-35 T 10-11-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 A4G23_RS05180 916cf93893328eb866b32943b324bb5e 329 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 2 329 1.4E-109 T 10-11-2016 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4G23_RS05180 916cf93893328eb866b32943b324bb5e 329 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 17 28 - T 10-11-2016 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4G23_RS05180 916cf93893328eb866b32943b324bb5e 329 Gene3D G3DSA:3.20.20.70 2 306 1.1E-78 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS05180 916cf93893328eb866b32943b324bb5e 329 Pfam PF13353 4Fe-4S single cluster domain 18 103 9.6E-7 T 10-11-2016 A4G23_RS05180 916cf93893328eb866b32943b324bb5e 329 SUPERFAMILY SSF102114 3 277 9.94E-72 T 10-11-2016 A4G23_RS05180 916cf93893328eb866b32943b324bb5e 329 Hamap MF_01225_B Cyclic pyranopterin monophosphate synthase [moaA]. 2 329 40.671 T 10-11-2016 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4G23_RS05180 916cf93893328eb866b32943b324bb5e 329 SMART SM00729 11 213 1.6E-9 T 10-11-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 A4G23_RS23250 1ee3357f91c14ff4f2f9a769a250c5a9 444 Pfam PF00581 Rhodanese-like domain 345 435 6.9E-10 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS23250 1ee3357f91c14ff4f2f9a769a250c5a9 444 Gene3D G3DSA:3.40.250.10 334 443 1.5E-20 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS23250 1ee3357f91c14ff4f2f9a769a250c5a9 444 SMART SM00450 342 440 4.5E-11 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS23250 1ee3357f91c14ff4f2f9a769a250c5a9 444 Gene3D G3DSA:3.40.50.1100 1 42 2.2E-56 T 10-11-2016 A4G23_RS23250 1ee3357f91c14ff4f2f9a769a250c5a9 444 Gene3D G3DSA:3.40.50.1100 156 311 2.2E-56 T 10-11-2016 A4G23_RS23250 1ee3357f91c14ff4f2f9a769a250c5a9 444 SUPERFAMILY SSF52821 334 443 4.19E-24 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS23250 1ee3357f91c14ff4f2f9a769a250c5a9 444 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 6 302 1.1E-48 T 10-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4G23_RS23250 1ee3357f91c14ff4f2f9a769a250c5a9 444 SUPERFAMILY SSF53686 3 313 2.62E-61 T 10-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4G23_RS23250 1ee3357f91c14ff4f2f9a769a250c5a9 444 Gene3D G3DSA:3.40.50.1100 43 129 1.9E-16 T 10-11-2016 A4G23_RS11245 a9845b34259aee6b4697c258df8ff017 83 Gene3D G3DSA:3.30.70.20 13 75 4.1E-8 T 10-11-2016 A4G23_RS11245 a9845b34259aee6b4697c258df8ff017 83 Pfam PF13459 4Fe-4S single cluster domain 15 70 2.6E-7 T 10-11-2016 A4G23_RS11245 a9845b34259aee6b4697c258df8ff017 83 SUPERFAMILY SSF54862 13 72 3.52E-5 T 10-11-2016 A4G23_RS26805 f53c65907ba5e3461ca66e1130de5368 254 Gene3D G3DSA:3.40.50.720 2 252 3.6E-86 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS26805 f53c65907ba5e3461ca66e1130de5368 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 251 6.1E-66 T 10-11-2016 A4G23_RS26805 f53c65907ba5e3461ca66e1130de5368 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 3.6E-9 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS26805 f53c65907ba5e3461ca66e1130de5368 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 3.6E-9 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS26805 f53c65907ba5e3461ca66e1130de5368 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 3.6E-9 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS26805 f53c65907ba5e3461ca66e1130de5368 254 SUPERFAMILY SSF51735 7 252 3.93E-81 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS26805 f53c65907ba5e3461ca66e1130de5368 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 3.2E-41 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS26805 f53c65907ba5e3461ca66e1130de5368 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 3.2E-41 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS26805 f53c65907ba5e3461ca66e1130de5368 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 3.2E-41 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS26805 f53c65907ba5e3461ca66e1130de5368 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 3.2E-41 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS26805 f53c65907ba5e3461ca66e1130de5368 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 3.2E-41 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS26805 f53c65907ba5e3461ca66e1130de5368 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 3.2E-41 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS26805 f53c65907ba5e3461ca66e1130de5368 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 10-11-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4G23_RS26805 f53c65907ba5e3461ca66e1130de5368 254 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 189 1.0E-5 T 10-11-2016 A4G23_RS17530 49be6fe5a8f7b5d831575a4c17c8d77a 272 Pfam PF13411 MerR HTH family regulatory protein 2 70 3.5E-11 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS17530 49be6fe5a8f7b5d831575a4c17c8d77a 272 Pfam PF06445 GyrI-like small molecule binding domain 136 269 1.8E-12 T 10-11-2016 IPR029442 GyrI-like small molecule binding domain A4G23_RS17530 49be6fe5a8f7b5d831575a4c17c8d77a 272 Gene3D G3DSA:3.20.80.10 120 270 1.7E-8 T 10-11-2016 IPR011256 Regulatory factor, effector binding domain A4G23_RS17530 49be6fe5a8f7b5d831575a4c17c8d77a 272 SMART SM00422 2 72 8.9E-14 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS17530 49be6fe5a8f7b5d831575a4c17c8d77a 272 SUPERFAMILY SSF55136 120 270 1.75E-17 T 10-11-2016 IPR011256 Regulatory factor, effector binding domain A4G23_RS17530 49be6fe5a8f7b5d831575a4c17c8d77a 272 SMART SM00871 119 271 9.5E-13 T 10-11-2016 IPR010499 Bacterial transcription activator, effector binding A4G23_RS17530 49be6fe5a8f7b5d831575a4c17c8d77a 272 SUPERFAMILY SSF46955 2 117 8.42E-24 T 10-11-2016 IPR009061 Putative DNA-binding domain A4G23_RS17530 49be6fe5a8f7b5d831575a4c17c8d77a 272 Gene3D G3DSA:1.10.1660.10 1 58 1.4E-20 T 10-11-2016 A4G23_RS17530 49be6fe5a8f7b5d831575a4c17c8d77a 272 Gene3D G3DSA:1.10.1660.10 59 118 3.0E-6 T 10-11-2016 A4G23_RS25120 ac3664e4271457193d48a257e00474a8 457 Gene3D G3DSA:1.25.40.80 195 269 4.9E-26 T 10-11-2016 A4G23_RS25120 ac3664e4271457193d48a257e00474a8 457 Pfam PF00875 DNA photolyase 4 168 8.1E-40 T 10-11-2016 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 A4G23_RS25120 ac3664e4271457193d48a257e00474a8 457 PRINTS PR00147 DNA photolyase signature 332 350 7.9E-26 T 10-11-2016 IPR002081 Cryptochrome/DNA photolyase class 1 A4G23_RS25120 ac3664e4271457193d48a257e00474a8 457 PRINTS PR00147 DNA photolyase signature 141 157 7.9E-26 T 10-11-2016 IPR002081 Cryptochrome/DNA photolyase class 1 A4G23_RS25120 ac3664e4271457193d48a257e00474a8 457 PRINTS PR00147 DNA photolyase signature 312 328 7.9E-26 T 10-11-2016 IPR002081 Cryptochrome/DNA photolyase class 1 A4G23_RS25120 ac3664e4271457193d48a257e00474a8 457 PRINTS PR00147 DNA photolyase signature 371 385 7.9E-26 T 10-11-2016 IPR002081 Cryptochrome/DNA photolyase class 1 A4G23_RS25120 ac3664e4271457193d48a257e00474a8 457 ProSitePatterns PS00394 DNA photolyases class 1 signature 1. 312 324 - T 10-11-2016 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal A4G23_RS25120 ac3664e4271457193d48a257e00474a8 457 Gene3D G3DSA:1.10.579.10 270 446 2.7E-67 T 10-11-2016 A4G23_RS25120 ac3664e4271457193d48a257e00474a8 457 Pfam PF03441 FAD binding domain of DNA photolyase 262 446 4.3E-69 T 10-11-2016 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 A4G23_RS25120 ac3664e4271457193d48a257e00474a8 457 SUPERFAMILY SSF48173 192 452 1.7E-89 T 10-11-2016 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 A4G23_RS25120 ac3664e4271457193d48a257e00474a8 457 SUPERFAMILY SSF52425 3 183 1.57E-37 T 10-11-2016 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 A4G23_RS25120 ac3664e4271457193d48a257e00474a8 457 ProSitePatterns PS00691 DNA photolyases class 1 signature 2. 332 351 - T 10-11-2016 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal A4G23_RS25120 ac3664e4271457193d48a257e00474a8 457 Gene3D G3DSA:3.40.50.620 2 164 1.5E-38 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS22980 96f032cd4359aa0bfbd3471f50c48c07 479 SUPERFAMILY SSF51658 23 251 3.62E-13 T 10-11-2016 IPR013022 Xylose isomerase-like, TIM barrel domain A4G23_RS22980 96f032cd4359aa0bfbd3471f50c48c07 479 Gene3D G3DSA:3.20.20.150 4 272 8.0E-86 T 10-11-2016 IPR013022 Xylose isomerase-like, TIM barrel domain A4G23_RS22980 96f032cd4359aa0bfbd3471f50c48c07 479 Pfam PF05114 Protein of unknown function (DUF692) 6 269 6.8E-82 T 10-11-2016 IPR007801 Uncharacterised protein family UPF0276 A4G23_RS11905 5361302d96fec4cebf65aecdfc9a5a6d 119 Pfam PF10745 Protein of unknown function (DUF2530) 11 78 1.7E-8 T 10-11-2016 IPR019681 Protein of unknown function DUF2530 A4G23_RS22410 a9c0993f011ef2d1b6b714282dbe553f 810 Pfam PF02624 YcaO cyclodehydratase, ATP-ad Mg2+-binding 531 801 1.1E-12 T 10-11-2016 IPR003776 YcaO-like domain A4G23_RS22410 a9c0993f011ef2d1b6b714282dbe553f 810 TIGRFAM TIGR03882 cyclo_dehyd_2: bacteriocin biosynthesis cyclodehydratase domain 264 394 5.4E-16 T 10-11-2016 IPR022291 Bacteriocin biosynthesis, cyclodehydratase domain A4G23_RS15710 edc6480ab430269f7d16999caee90c43 254 PRINTS PR00111 Alpha/beta hydrolase fold signature 95 108 8.5E-10 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS15710 edc6480ab430269f7d16999caee90c43 254 PRINTS PR00111 Alpha/beta hydrolase fold signature 109 122 8.5E-10 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS15710 edc6480ab430269f7d16999caee90c43 254 PRINTS PR00111 Alpha/beta hydrolase fold signature 50 65 8.5E-10 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS15710 edc6480ab430269f7d16999caee90c43 254 Pfam PF00561 alpha/beta hydrolase fold 26 129 1.8E-16 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS15710 edc6480ab430269f7d16999caee90c43 254 SUPERFAMILY SSF53474 6 253 4.19E-40 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS15710 edc6480ab430269f7d16999caee90c43 254 Gene3D G3DSA:3.40.50.1820 5 253 1.7E-37 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS00790 bc1b84b9e275d06eba43770e47a49293 568 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 199 209 - T 10-11-2016 IPR022398 Peptidase S8, subtilisin, His-active site A4G23_RS00790 bc1b84b9e275d06eba43770e47a49293 568 Gene3D G3DSA:3.40.50.200 96 447 8.9E-80 T 10-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4G23_RS00790 bc1b84b9e275d06eba43770e47a49293 568 Pfam PF00082 Subtilase family 129 433 2.6E-49 T 10-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4G23_RS00790 bc1b84b9e275d06eba43770e47a49293 568 Gene3D G3DSA:2.60.120.260 464 568 8.7E-18 T 10-11-2016 IPR008979 Galactose-binding domain-like A4G23_RS00790 bc1b84b9e275d06eba43770e47a49293 568 SUPERFAMILY SSF52743 81 168 2.09E-68 T 10-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4G23_RS00790 bc1b84b9e275d06eba43770e47a49293 568 SUPERFAMILY SSF52743 198 446 2.09E-68 T 10-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4G23_RS00790 bc1b84b9e275d06eba43770e47a49293 568 Pfam PF01483 Proprotein convertase P-domain 488 568 3.2E-20 T 10-11-2016 IPR002884 Proprotein convertase, P GO:0004252|GO:0006508 A4G23_RS00790 bc1b84b9e275d06eba43770e47a49293 568 PRINTS PR00723 Subtilisin serine protease family (S8) signature 195 208 2.3E-16 T 10-11-2016 IPR015500 Peptidase S8, subtilisin-related A4G23_RS00790 bc1b84b9e275d06eba43770e47a49293 568 PRINTS PR00723 Subtilisin serine protease family (S8) signature 129 148 2.3E-16 T 10-11-2016 IPR015500 Peptidase S8, subtilisin-related A4G23_RS00790 bc1b84b9e275d06eba43770e47a49293 568 PRINTS PR00723 Subtilisin serine protease family (S8) signature 386 402 2.3E-16 T 10-11-2016 IPR015500 Peptidase S8, subtilisin-related A4G23_RS00790 bc1b84b9e275d06eba43770e47a49293 568 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 387 397 - T 10-11-2016 IPR023828 Peptidase S8, subtilisin, Ser-active site A4G23_RS00790 bc1b84b9e275d06eba43770e47a49293 568 SUPERFAMILY SSF49785 464 568 4.68E-25 T 10-11-2016 IPR008979 Galactose-binding domain-like A4G23_RS16605 6cf5158c854a87c46651889236fa3e09 214 Pfam PF00297 Ribosomal protein L3 98 186 2.9E-15 T 10-11-2016 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS16605 6cf5158c854a87c46651889236fa3e09 214 ProSitePatterns PS00474 Ribosomal protein L3 signature. 105 128 - T 10-11-2016 IPR019926 Ribosomal protein L3, conserved site A4G23_RS16605 6cf5158c854a87c46651889236fa3e09 214 Gene3D G3DSA:2.40.30.10 162 211 4.5E-12 T 10-11-2016 A4G23_RS16605 6cf5158c854a87c46651889236fa3e09 214 Gene3D G3DSA:2.40.30.10 7 36 4.5E-12 T 10-11-2016 A4G23_RS16605 6cf5158c854a87c46651889236fa3e09 214 Gene3D G3DSA:4.10.960.10 80 161 1.4E-33 T 10-11-2016 A4G23_RS16605 6cf5158c854a87c46651889236fa3e09 214 SUPERFAMILY SSF50447 5 212 7.77E-81 T 10-11-2016 IPR009000 Translation protein, beta-barrel domain A4G23_RS16605 6cf5158c854a87c46651889236fa3e09 214 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 5 211 40.027 T 10-11-2016 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS16605 6cf5158c854a87c46651889236fa3e09 214 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 7 208 9.2E-91 T 10-11-2016 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS17830 7c16ae97931d0bf950924de7974ced07 587 SUPERFAMILY SSF52440 2 112 2.3E-46 T 10-11-2016 IPR016185 Pre-ATP-grasp domain A4G23_RS17830 7c16ae97931d0bf950924de7974ced07 587 Pfam PF02785 Biotin carboxylase C-terminal domain 333 443 2.1E-35 T 10-11-2016 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4G23_RS17830 7c16ae97931d0bf950924de7974ced07 587 Gene3D G3DSA:3.30.1490.20 129 201 4.3E-21 T 10-11-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A4G23_RS17830 7c16ae97931d0bf950924de7974ced07 587 Pfam PF00364 Biotin-requiring enzyme 519 585 1.1E-16 T 10-11-2016 IPR000089 Biotin/lipoyl attachment A4G23_RS17830 7c16ae97931d0bf950924de7974ced07 587 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 542 559 - T 10-11-2016 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4G23_RS17830 7c16ae97931d0bf950924de7974ced07 587 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 109 7.2E-44 T 10-11-2016 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4G23_RS17830 7c16ae97931d0bf950924de7974ced07 587 SUPERFAMILY SSF56059 114 321 2.83E-59 T 10-11-2016 A4G23_RS17830 7c16ae97931d0bf950924de7974ced07 587 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 285 292 - T 10-11-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A4G23_RS17830 7c16ae97931d0bf950924de7974ced07 587 SMART SM00878 333 443 2.8E-56 T 10-11-2016 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4G23_RS17830 7c16ae97931d0bf950924de7974ced07 587 SUPERFAMILY SSF51246 328 444 3.35E-36 T 10-11-2016 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4G23_RS17830 7c16ae97931d0bf950924de7974ced07 587 SUPERFAMILY SSF51230 511 585 1.1E-19 T 10-11-2016 IPR011053 Single hybrid motif A4G23_RS17830 7c16ae97931d0bf950924de7974ced07 587 Gene3D G3DSA:2.40.50.100 513 586 1.5E-22 T 10-11-2016 A4G23_RS17830 7c16ae97931d0bf950924de7974ced07 587 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 114 320 1.5E-75 T 10-11-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A4G23_RS17830 7c16ae97931d0bf950924de7974ced07 587 Gene3D G3DSA:3.40.50.20 2 128 1.7E-49 T 10-11-2016 IPR016185 Pre-ATP-grasp domain A4G23_RS17830 7c16ae97931d0bf950924de7974ced07 587 Gene3D G3DSA:3.30.470.20 203 446 7.2E-90 T 10-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 A4G23_RS05945 22eb7d384be5050f429afc6795371982 124 Gene3D G3DSA:3.10.180.10 5 115 1.6E-8 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS05945 22eb7d384be5050f429afc6795371982 124 SUPERFAMILY SSF54593 4 115 1.78E-11 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS15430 4f295ef05fba13b63970ca46d9aa54d8 841 SUPERFAMILY SSF81923 3 144 2.94E-33 T 10-11-2016 IPR004176 Clp, N-terminal GO:0019538 A4G23_RS15430 4f295ef05fba13b63970ca46d9aa54d8 841 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 720 799 1.9E-25 T 10-11-2016 IPR019489 Clp ATPase, C-terminal A4G23_RS15430 4f295ef05fba13b63970ca46d9aa54d8 841 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 16 68 3.2E-19 T 10-11-2016 IPR004176 Clp, N-terminal GO:0019538 A4G23_RS15430 4f295ef05fba13b63970ca46d9aa54d8 841 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 93 142 4.5E-17 T 10-11-2016 IPR004176 Clp, N-terminal GO:0019538 A4G23_RS15430 4f295ef05fba13b63970ca46d9aa54d8 841 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 210 322 1.6E-12 T 10-11-2016 IPR003959 ATPase, AAA-type, core GO:0005524 A4G23_RS15430 4f295ef05fba13b63970ca46d9aa54d8 841 SUPERFAMILY SSF52540 168 464 5.95E-74 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS15430 4f295ef05fba13b63970ca46d9aa54d8 841 Gene3D G3DSA:1.10.1780.10 1 142 3.1E-54 T 10-11-2016 IPR004176 Clp, N-terminal GO:0019538 A4G23_RS15430 4f295ef05fba13b63970ca46d9aa54d8 841 Gene3D G3DSA:1.10.8.60 732 817 4.2E-31 T 10-11-2016 A4G23_RS15430 4f295ef05fba13b63970ca46d9aa54d8 841 SMART SM00382 542 690 8.4E-12 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS15430 4f295ef05fba13b63970ca46d9aa54d8 841 SMART SM00382 205 349 6.5E-10 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS15430 4f295ef05fba13b63970ca46d9aa54d8 841 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 300 312 - T 10-11-2016 IPR018368 ClpA/B, conserved site 1 GO:0005524 A4G23_RS15430 4f295ef05fba13b63970ca46d9aa54d8 841 SMART SM01086 720 813 7.5E-37 T 10-11-2016 IPR019489 Clp ATPase, C-terminal A4G23_RS15430 4f295ef05fba13b63970ca46d9aa54d8 841 Pfam PF07724 AAA domain (Cdc48 subfamily) 542 713 3.5E-54 T 10-11-2016 IPR003959 ATPase, AAA-type, core GO:0005524 A4G23_RS15430 4f295ef05fba13b63970ca46d9aa54d8 841 Gene3D G3DSA:1.10.8.60 351 433 5.7E-34 T 10-11-2016 A4G23_RS15430 4f295ef05fba13b63970ca46d9aa54d8 841 Pfam PF02151 UvrB/uvrC motif 422 454 5.2E-7 T 10-11-2016 IPR001943 UVR domain GO:0005515 A4G23_RS15430 4f295ef05fba13b63970ca46d9aa54d8 841 SUPERFAMILY SSF52540 491 802 1.8E-78 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS15430 4f295ef05fba13b63970ca46d9aa54d8 841 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 620 638 6.2E-40 T 10-11-2016 IPR001270 ClpA/B family GO:0005524 A4G23_RS15430 4f295ef05fba13b63970ca46d9aa54d8 841 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 653 667 6.2E-40 T 10-11-2016 IPR001270 ClpA/B family GO:0005524 A4G23_RS15430 4f295ef05fba13b63970ca46d9aa54d8 841 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 546 564 6.2E-40 T 10-11-2016 IPR001270 ClpA/B family GO:0005524 A4G23_RS15430 4f295ef05fba13b63970ca46d9aa54d8 841 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 591 609 6.2E-40 T 10-11-2016 IPR001270 ClpA/B family GO:0005524 A4G23_RS15430 4f295ef05fba13b63970ca46d9aa54d8 841 Gene3D G3DSA:3.40.50.300 168 348 5.2E-47 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS15430 4f295ef05fba13b63970ca46d9aa54d8 841 Gene3D G3DSA:3.40.50.300 495 668 1.3E-58 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS15430 4f295ef05fba13b63970ca46d9aa54d8 841 Gene3D G3DSA:3.40.50.300 703 731 1.3E-58 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS24945 568ad2f467b6a7432baa32b13f491ca3 264 Gene3D G3DSA:3.40.50.1110 16 202 1.6E-39 T 10-11-2016 IPR013830 SGNH hydrolase-type esterase domain A4G23_RS24945 568ad2f467b6a7432baa32b13f491ca3 264 SUPERFAMILY SSF52266 16 202 7.63E-37 T 10-11-2016 IPR013830 SGNH hydrolase-type esterase domain A4G23_RS24945 568ad2f467b6a7432baa32b13f491ca3 264 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 18 192 1.8E-28 T 10-11-2016 IPR013830 SGNH hydrolase-type esterase domain A4G23_RS03515 374e8b93931baa8de6af31f2028bedfa 402 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 7 397 2.8E-118 T 10-11-2016 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5 A4G23_RS03515 374e8b93931baa8de6af31f2028bedfa 402 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 187 371 6.5E-69 T 10-11-2016 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 A4G23_RS03515 374e8b93931baa8de6af31f2028bedfa 402 Gene3D G3DSA:3.40.50.10300 185 400 2.8E-78 T 10-11-2016 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 A4G23_RS03515 374e8b93931baa8de6af31f2028bedfa 402 SUPERFAMILY SSF52507 5 178 2.49E-58 T 10-11-2016 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 A4G23_RS03515 374e8b93931baa8de6af31f2028bedfa 402 Pfam PF02441 Flavoprotein 7 132 1.2E-32 T 10-11-2016 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 A4G23_RS03515 374e8b93931baa8de6af31f2028bedfa 402 SUPERFAMILY SSF102645 186 400 1.96E-66 T 10-11-2016 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 A4G23_RS03515 374e8b93931baa8de6af31f2028bedfa 402 Gene3D G3DSA:3.40.50.1950 5 179 6.2E-62 T 10-11-2016 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 A4G23_RS01890 299f28daf5d13a9f381db14caf411964 342 Pfam PF13377 Periplasmic binding protein-like domain 182 336 1.3E-24 T 10-11-2016 A4G23_RS01890 299f28daf5d13a9f381db14caf411964 342 Gene3D G3DSA:1.10.260.40 14 65 2.2E-22 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS01890 299f28daf5d13a9f381db14caf411964 342 ProSitePatterns PS00356 LacI-type HTH domain signature. 18 36 - T 10-11-2016 A4G23_RS01890 299f28daf5d13a9f381db14caf411964 342 Gene3D G3DSA:3.40.50.2300 66 186 8.9E-38 T 10-11-2016 A4G23_RS01890 299f28daf5d13a9f381db14caf411964 342 SUPERFAMILY SSF53822 75 337 2.52E-55 T 10-11-2016 IPR028082 Periplasmic binding protein-like I A4G23_RS01890 299f28daf5d13a9f381db14caf411964 342 SUPERFAMILY SSF47413 15 73 5.63E-16 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS01890 299f28daf5d13a9f381db14caf411964 342 Pfam PF00356 Bacterial regulatory proteins, lacI family 17 62 1.9E-14 T 10-11-2016 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4G23_RS01890 299f28daf5d13a9f381db14caf411964 342 SMART SM00354 15 85 1.1E-23 T 10-11-2016 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4G23_RS01890 299f28daf5d13a9f381db14caf411964 342 Gene3D G3DSA:3.40.50.2300 187 317 1.1E-36 T 10-11-2016 A4G23_RS05860 face5ea6eed27cc41233ed67e5bcc9ae 884 SUPERFAMILY SSF47807 166 274 4.78E-28 T 10-11-2016 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 A4G23_RS05860 face5ea6eed27cc41233ed67e5bcc9ae 884 SUPERFAMILY SSF88723 2 165 1.3E-50 T 10-11-2016 IPR029060 PIN domain-like A4G23_RS05860 face5ea6eed27cc41233ed67e5bcc9ae 884 Gene3D G3DSA:3.40.50.1010 2 180 3.0E-64 T 10-11-2016 IPR029060 PIN domain-like A4G23_RS05860 face5ea6eed27cc41233ed67e5bcc9ae 884 SMART SM00475 1 256 4.5E-132 T 10-11-2016 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 A4G23_RS05860 face5ea6eed27cc41233ed67e5bcc9ae 884 Gene3D G3DSA:1.10.150.20 667 773 6.7E-32 T 10-11-2016 A4G23_RS05860 face5ea6eed27cc41233ed67e5bcc9ae 884 Gene3D G3DSA:3.30.70.370 618 666 8.5E-65 T 10-11-2016 A4G23_RS05860 face5ea6eed27cc41233ed67e5bcc9ae 884 Gene3D G3DSA:3.30.70.370 774 882 8.5E-65 T 10-11-2016 A4G23_RS05860 face5ea6eed27cc41233ed67e5bcc9ae 884 SMART SM00474 303 473 1.0E-8 T 10-11-2016 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 A4G23_RS05860 face5ea6eed27cc41233ed67e5bcc9ae 884 SMART SM00279 168 203 4.3E-14 T 10-11-2016 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 A4G23_RS05860 face5ea6eed27cc41233ed67e5bcc9ae 884 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 1 165 2.6E-51 T 10-11-2016 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 A4G23_RS05860 face5ea6eed27cc41233ed67e5bcc9ae 884 Gene3D G3DSA:1.10.150.20 181 240 1.6E-24 T 10-11-2016 A4G23_RS05860 face5ea6eed27cc41233ed67e5bcc9ae 884 SMART SM00482 640 847 1.2E-115 T 10-11-2016 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4G23_RS05860 face5ea6eed27cc41233ed67e5bcc9ae 884 SUPERFAMILY SSF56672 480 881 6.12E-140 T 10-11-2016 A4G23_RS05860 face5ea6eed27cc41233ed67e5bcc9ae 884 Pfam PF00476 DNA polymerase family A 506 880 7.0E-142 T 10-11-2016 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4G23_RS05860 face5ea6eed27cc41233ed67e5bcc9ae 884 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 167 259 8.8E-27 T 10-11-2016 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 A4G23_RS05860 face5ea6eed27cc41233ed67e5bcc9ae 884 SUPERFAMILY SSF53098 306 474 1.38E-29 T 10-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 A4G23_RS05860 face5ea6eed27cc41233ed67e5bcc9ae 884 TIGRFAM TIGR00593 pola: DNA polymerase I 1 882 2.4E-295 T 10-11-2016 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4G23_RS05860 face5ea6eed27cc41233ed67e5bcc9ae 884 Gene3D G3DSA:1.20.1060.10 499 617 5.6E-33 T 10-11-2016 A4G23_RS05860 face5ea6eed27cc41233ed67e5bcc9ae 884 PRINTS PR00868 DNA-polymerase family A (pol I) signature 830 843 1.6E-76 T 10-11-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4G23_RS05860 face5ea6eed27cc41233ed67e5bcc9ae 884 PRINTS PR00868 DNA-polymerase family A (pol I) signature 609 631 1.6E-76 T 10-11-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4G23_RS05860 face5ea6eed27cc41233ed67e5bcc9ae 884 PRINTS PR00868 DNA-polymerase family A (pol I) signature 685 698 1.6E-76 T 10-11-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4G23_RS05860 face5ea6eed27cc41233ed67e5bcc9ae 884 PRINTS PR00868 DNA-polymerase family A (pol I) signature 709 734 1.6E-76 T 10-11-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4G23_RS05860 face5ea6eed27cc41233ed67e5bcc9ae 884 PRINTS PR00868 DNA-polymerase family A (pol I) signature 800 816 1.6E-76 T 10-11-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4G23_RS05860 face5ea6eed27cc41233ed67e5bcc9ae 884 PRINTS PR00868 DNA-polymerase family A (pol I) signature 655 678 1.6E-76 T 10-11-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4G23_RS05860 face5ea6eed27cc41233ed67e5bcc9ae 884 PRINTS PR00868 DNA-polymerase family A (pol I) signature 768 779 1.6E-76 T 10-11-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4G23_RS05860 face5ea6eed27cc41233ed67e5bcc9ae 884 PRINTS PR00868 DNA-polymerase family A (pol I) signature 632 647 1.6E-76 T 10-11-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4G23_RS05860 face5ea6eed27cc41233ed67e5bcc9ae 884 PRINTS PR00868 DNA-polymerase family A (pol I) signature 746 757 1.6E-76 T 10-11-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4G23_RS05860 face5ea6eed27cc41233ed67e5bcc9ae 884 Pfam PF01612 3'-5' exonuclease 356 432 1.3E-4 T 10-11-2016 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 A4G23_RS05860 face5ea6eed27cc41233ed67e5bcc9ae 884 Gene3D G3DSA:3.30.420.10 306 497 2.0E-49 T 10-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 A4G23_RS18095 8ca5fd2e60e1f3d7a2d0fa83b359bb00 242 TIGRFAM TIGR03177 pilus_cpaB: Flp pilus assembly protein CpaB 10 225 1.6E-23 T 10-11-2016 IPR017592 Pilus assembly, Flp-type CpaB A4G23_RS18095 8ca5fd2e60e1f3d7a2d0fa83b359bb00 242 SMART SM00858 41 103 9.1E-4 T 10-11-2016 IPR013974 SAF domain Reactome: R-HSA-4085001 A4G23_RS18095 8ca5fd2e60e1f3d7a2d0fa83b359bb00 242 Pfam PF16976 Flp pilus assembly protein RcpC/CpaB 107 218 2.1E-18 T 10-11-2016 IPR031571 Flp pilus assembly protein RcpC/CpaB domain A4G23_RS01045 67782b56474155774166fabc1e8f8dcc 318 Gene3D G3DSA:3.90.550.10 20 219 1.3E-28 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS01045 67782b56474155774166fabc1e8f8dcc 318 Pfam PF00535 Glycosyl transferase family 2 21 178 1.9E-16 T 10-11-2016 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A4G23_RS01045 67782b56474155774166fabc1e8f8dcc 318 SUPERFAMILY SSF53448 11 227 1.22E-35 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS10080 44b98f7cc504ba7d9ba95bcc9ec5a48c 279 Gene3D G3DSA:3.40.50.1820 5 232 6.8E-21 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS10080 44b98f7cc504ba7d9ba95bcc9ec5a48c 279 SUPERFAMILY SSF53474 3 234 7.69E-31 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS10080 44b98f7cc504ba7d9ba95bcc9ec5a48c 279 Pfam PF00975 Thioesterase domain 5 232 7.8E-26 T 10-11-2016 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 A4G23_RS13785 45559f61fb6005ef3868f6dd82eedca6 425 Gene3D G3DSA:3.30.930.10 104 418 7.0E-125 T 10-11-2016 A4G23_RS13785 45559f61fb6005ef3868f6dd82eedca6 425 TIGRFAM TIGR00414 serS: serine--tRNA ligase 2 414 1.4E-133 T 10-11-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A4G23_RS13785 45559f61fb6005ef3868f6dd82eedca6 425 SUPERFAMILY SSF46589 2 111 6.8E-24 T 10-11-2016 IPR010978 tRNA-binding arm GO:0000166 A4G23_RS13785 45559f61fb6005ef3868f6dd82eedca6 425 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 221 397 4.3E-31 T 10-11-2016 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4G23_RS13785 45559f61fb6005ef3868f6dd82eedca6 425 SUPERFAMILY SSF55681 131 417 7.21E-86 T 10-11-2016 A4G23_RS13785 45559f61fb6005ef3868f6dd82eedca6 425 PIRSF PIRSF001529 1 423 1.9E-141 T 10-11-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A4G23_RS13785 45559f61fb6005ef3868f6dd82eedca6 425 Gene3D G3DSA:1.10.287.40 2 102 1.4E-27 T 10-11-2016 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A4G23_RS13785 45559f61fb6005ef3868f6dd82eedca6 425 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 419 39.373 T 10-11-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A4G23_RS13785 45559f61fb6005ef3868f6dd82eedca6 425 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 106 2.4E-23 T 10-11-2016 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A4G23_RS13785 45559f61fb6005ef3868f6dd82eedca6 425 PRINTS PR00981 Seryl-tRNA synthetase signature 332 348 4.3E-30 T 10-11-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A4G23_RS13785 45559f61fb6005ef3868f6dd82eedca6 425 PRINTS PR00981 Seryl-tRNA synthetase signature 263 275 4.3E-30 T 10-11-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A4G23_RS13785 45559f61fb6005ef3868f6dd82eedca6 425 PRINTS PR00981 Seryl-tRNA synthetase signature 350 366 4.3E-30 T 10-11-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A4G23_RS13785 45559f61fb6005ef3868f6dd82eedca6 425 PRINTS PR00981 Seryl-tRNA synthetase signature 275 288 4.3E-30 T 10-11-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A4G23_RS13785 45559f61fb6005ef3868f6dd82eedca6 425 PRINTS PR00981 Seryl-tRNA synthetase signature 315 328 4.3E-30 T 10-11-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A4G23_RS16680 802c77ec3039acaa6e6832eb21f7f905 179 PIRSF PIRSF002162 1 178 2.5E-47 T 10-11-2016 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS16680 802c77ec3039acaa6e6832eb21f7f905 179 Gene3D G3DSA:3.90.930.12 84 178 6.1E-38 T 10-11-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS16680 802c77ec3039acaa6e6832eb21f7f905 179 SUPERFAMILY SSF56053 1 83 7.2E-27 T 10-11-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS16680 802c77ec3039acaa6e6832eb21f7f905 179 Pfam PF00347 Ribosomal protein L6 92 165 2.9E-19 T 10-11-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS16680 802c77ec3039acaa6e6832eb21f7f905 179 Pfam PF00347 Ribosomal protein L6 11 83 1.2E-19 T 10-11-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS16680 802c77ec3039acaa6e6832eb21f7f905 179 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 177 3.2E-73 T 10-11-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 A4G23_RS16680 802c77ec3039acaa6e6832eb21f7f905 179 PRINTS PR00059 Ribosomal protein L6 signature 72 97 4.7E-32 T 10-11-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 A4G23_RS16680 802c77ec3039acaa6e6832eb21f7f905 179 PRINTS PR00059 Ribosomal protein L6 signature 100 116 4.7E-32 T 10-11-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 A4G23_RS16680 802c77ec3039acaa6e6832eb21f7f905 179 PRINTS PR00059 Ribosomal protein L6 signature 142 163 4.7E-32 T 10-11-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 A4G23_RS16680 802c77ec3039acaa6e6832eb21f7f905 179 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 155 163 - T 10-11-2016 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS16680 802c77ec3039acaa6e6832eb21f7f905 179 SUPERFAMILY SSF56053 84 177 7.33E-35 T 10-11-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS16680 802c77ec3039acaa6e6832eb21f7f905 179 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 177 38.095 T 10-11-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 A4G23_RS16680 802c77ec3039acaa6e6832eb21f7f905 179 Gene3D G3DSA:3.90.930.12 2 83 6.1E-30 T 10-11-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS17450 d71205d153b0ebba1405554fcf25be3a 271 Pfam PF13419 Haloacid dehalogenase-like hydrolase 16 198 5.1E-17 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS17450 d71205d153b0ebba1405554fcf25be3a 271 Gene3D G3DSA:3.40.50.1000 105 201 5.7E-20 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS17450 d71205d153b0ebba1405554fcf25be3a 271 Gene3D G3DSA:3.40.50.1000 13 65 5.7E-20 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS17450 d71205d153b0ebba1405554fcf25be3a 271 SUPERFAMILY SSF56784 11 199 2.58E-31 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS16685 2f0afaf6cf66f72bda6018d828de9ccf 127 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 17 127 4.6E-38 T 10-11-2016 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS16685 2f0afaf6cf66f72bda6018d828de9ccf 127 SUPERFAMILY SSF53137 16 125 5.89E-46 T 10-11-2016 A4G23_RS16685 2f0afaf6cf66f72bda6018d828de9ccf 127 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 14 127 1.6E-47 T 10-11-2016 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS16685 2f0afaf6cf66f72bda6018d828de9ccf 127 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 13 127 26.266 T 10-11-2016 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS16685 2f0afaf6cf66f72bda6018d828de9ccf 127 Gene3D G3DSA:3.30.420.100 31 127 3.0E-38 T 10-11-2016 A4G23_RS21215 3e4100ab61b355120afe34376094376d 474 Pfam PF00672 HAMP domain 178 241 3.0E-13 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS21215 3e4100ab61b355120afe34376094376d 474 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 352 460 3.7E-15 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS21215 3e4100ab61b355120afe34376094376d 474 SUPERFAMILY SSF55874 298 459 3.41E-31 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS21215 3e4100ab61b355120afe34376094376d 474 PRINTS PR00344 Bacterial sensor protein C-terminal signature 388 402 3.3E-7 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS21215 3e4100ab61b355120afe34376094376d 474 PRINTS PR00344 Bacterial sensor protein C-terminal signature 445 458 3.3E-7 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS21215 3e4100ab61b355120afe34376094376d 474 PRINTS PR00344 Bacterial sensor protein C-terminal signature 421 439 3.3E-7 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS21215 3e4100ab61b355120afe34376094376d 474 Gene3D G3DSA:3.30.565.10 312 464 5.9E-31 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS21215 3e4100ab61b355120afe34376094376d 474 SMART SM00388 246 309 1.7E-13 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS21215 3e4100ab61b355120afe34376094376d 474 SUPERFAMILY SSF158472 193 243 1.1E-7 T 10-11-2016 A4G23_RS21215 3e4100ab61b355120afe34376094376d 474 Gene3D G3DSA:1.10.287.130 236 304 9.9E-13 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS21215 3e4100ab61b355120afe34376094376d 474 SMART SM00387 351 461 3.7E-25 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS21215 3e4100ab61b355120afe34376094376d 474 SMART SM00304 192 245 3.6E-12 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS21215 3e4100ab61b355120afe34376094376d 474 Pfam PF00512 His Kinase A (phospho-acceptor) domain 247 308 1.3E-11 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS21215 3e4100ab61b355120afe34376094376d 474 SUPERFAMILY SSF47384 229 307 3.92E-14 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS01705 0a465edce32a71c2d52760d3d34b9377 221 SUPERFAMILY SSF48371 12 188 2.67E-15 T 10-11-2016 IPR016024 Armadillo-type fold GO:0005488 A4G23_RS01705 0a465edce32a71c2d52760d3d34b9377 221 Gene3D G3DSA:1.25.10.10 13 187 1.7E-14 T 10-11-2016 IPR011989 Armadillo-like helical A4G23_RS08360 616ec824ccb846f31664f05187546ade 162 Gene3D G3DSA:3.40.1400.10 1 149 1.0E-54 T 10-11-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 A4G23_RS08360 616ec824ccb846f31664f05187546ade 162 TIGRFAM TIGR02133 RPI_actino: ribose 5-phosphate isomerase 1 148 1.7E-73 T 10-11-2016 IPR011860 Ribose 5-phosphate isomerase GO:0004751 A4G23_RS08360 616ec824ccb846f31664f05187546ade 162 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 147 1.6E-53 T 10-11-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 A4G23_RS08360 616ec824ccb846f31664f05187546ade 162 Pfam PF02502 Ribose/Galactose Isomerase 3 142 1.5E-45 T 10-11-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 A4G23_RS08360 616ec824ccb846f31664f05187546ade 162 SUPERFAMILY SSF89623 1 151 7.59E-53 T 10-11-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 A4G23_RS08360 616ec824ccb846f31664f05187546ade 162 PIRSF PIRSF005384 1 149 3.2E-50 T 10-11-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 A4G23_RS22165 f2d478eff3bde880759a6e1a3e141a6f 406 Gene3D G3DSA:3.30.470.20 141 325 2.1E-17 T 10-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 A4G23_RS22165 f2d478eff3bde880759a6e1a3e141a6f 406 SUPERFAMILY SSF56059 100 318 6.87E-29 T 10-11-2016 A4G23_RS22165 f2d478eff3bde880759a6e1a3e141a6f 406 Pfam PF13535 ATP-grasp domain 146 284 1.8E-9 T 10-11-2016 A4G23_RS12600 df5a147a070f2168676e66e383a97cf5 163 Pfam PF13581 Histidine kinase-like ATPase domain 24 119 1.4E-8 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS12600 df5a147a070f2168676e66e383a97cf5 163 SUPERFAMILY SSF55874 42 124 3.21E-6 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS15315 f5052dd69c590661f732a239eb6b5685 380 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS15315 f5052dd69c590661f732a239eb6b5685 380 SUPERFAMILY SSF54631 251 377 4.45E-6 T 10-11-2016 A4G23_RS15315 f5052dd69c590661f732a239eb6b5685 380 Gene3D G3DSA:3.10.580.10 320 379 2.7E-5 T 10-11-2016 A4G23_RS15315 f5052dd69c590661f732a239eb6b5685 380 Pfam PF00005 ABC transporter 19 164 4.4E-33 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS15315 f5052dd69c590661f732a239eb6b5685 380 SMART SM00382 27 214 8.5E-18 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS15315 f5052dd69c590661f732a239eb6b5685 380 SUPERFAMILY SSF52540 1 240 4.62E-74 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS15315 f5052dd69c590661f732a239eb6b5685 380 Gene3D G3DSA:3.40.50.300 1 237 1.1E-75 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS13920 e2ed984dd3cdb5298c9f190e265424bc 495 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 26 435 3.6E-70 T 10-11-2016 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 A4G23_RS13920 e2ed984dd3cdb5298c9f190e265424bc 495 Gene3D G3DSA:1.20.1250.20 22 211 3.2E-34 T 10-11-2016 A4G23_RS13920 e2ed984dd3cdb5298c9f190e265424bc 495 PRINTS PR01036 Tetracycline resistance protein TetB signature 29 53 8.1E-10 T 10-11-2016 A4G23_RS13920 e2ed984dd3cdb5298c9f190e265424bc 495 PRINTS PR01036 Tetracycline resistance protein TetB signature 89 111 8.1E-10 T 10-11-2016 A4G23_RS13920 e2ed984dd3cdb5298c9f190e265424bc 495 PRINTS PR01036 Tetracycline resistance protein TetB signature 413 432 8.1E-10 T 10-11-2016 A4G23_RS13920 e2ed984dd3cdb5298c9f190e265424bc 495 PRINTS PR01036 Tetracycline resistance protein TetB signature 150 174 8.1E-10 T 10-11-2016 A4G23_RS13920 e2ed984dd3cdb5298c9f190e265424bc 495 SUPERFAMILY SSF103473 260 432 1.02E-67 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS13920 e2ed984dd3cdb5298c9f190e265424bc 495 SUPERFAMILY SSF103473 467 493 1.02E-67 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS13920 e2ed984dd3cdb5298c9f190e265424bc 495 SUPERFAMILY SSF103473 7 212 1.02E-67 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS13920 e2ed984dd3cdb5298c9f190e265424bc 495 ProSitePatterns PS00216 Sugar transport proteins signature 1. 80 96 - T 10-11-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A4G23_RS13920 e2ed984dd3cdb5298c9f190e265424bc 495 Gene3D G3DSA:1.20.1250.20 270 433 7.8E-13 T 10-11-2016 A4G23_RS13920 e2ed984dd3cdb5298c9f190e265424bc 495 Gene3D G3DSA:1.20.1250.20 468 492 7.8E-13 T 10-11-2016 A4G23_RS13920 e2ed984dd3cdb5298c9f190e265424bc 495 Pfam PF07690 Major Facilitator Superfamily 30 422 3.4E-54 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS22110 c47e34f30b3eca22c745dce721368808 143 SUPERFAMILY SSF54593 9 127 1.48E-21 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS22110 c47e34f30b3eca22c745dce721368808 143 Gene3D G3DSA:3.10.180.10 6 127 1.1E-30 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS22110 c47e34f30b3eca22c745dce721368808 143 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 12 122 1.9E-6 T 10-11-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4G23_RS17620 39845f28ffac0ae03795b864af33b1a0 236 Gene3D G3DSA:2.40.440.10 124 230 7.4E-13 T 10-11-2016 A4G23_RS17620 39845f28ffac0ae03795b864af33b1a0 236 SUPERFAMILY SSF47090 54 102 2.55E-6 T 10-11-2016 IPR002477 Peptidoglycan binding-like A4G23_RS17620 39845f28ffac0ae03795b864af33b1a0 236 Gene3D G3DSA:1.10.101.10 57 103 8.0E-6 T 10-11-2016 IPR002477 Peptidoglycan binding-like A4G23_RS17620 39845f28ffac0ae03795b864af33b1a0 236 SUPERFAMILY SSF141523 119 230 4.45E-20 T 10-11-2016 A4G23_RS17620 39845f28ffac0ae03795b864af33b1a0 236 Pfam PF03734 L,D-transpeptidase catalytic domain 120 229 3.5E-14 T 10-11-2016 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 A4G23_RS03560 92f2a7abbb5460ece194ed34a72f7342 437 Gene3D G3DSA:3.20.20.140 75 416 6.6E-106 T 10-11-2016 A4G23_RS03560 92f2a7abbb5460ece194ed34a72f7342 437 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 18 433 1.1E-126 T 10-11-2016 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 A4G23_RS03560 92f2a7abbb5460ece194ed34a72f7342 437 SUPERFAMILY SSF51556 60 373 4.63E-101 T 10-11-2016 IPR032466 Metal-dependent hydrolase A4G23_RS03560 92f2a7abbb5460ece194ed34a72f7342 437 Hamap MF_00220_B Dihydroorotase [pyrC]. 3 434 43.477 T 10-11-2016 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 A4G23_RS03560 92f2a7abbb5460ece194ed34a72f7342 437 Gene3D G3DSA:2.30.40.10 3 74 2.4E-16 T 10-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4G23_RS03560 92f2a7abbb5460ece194ed34a72f7342 437 Pfam PF01979 Amidohydrolase family 56 428 1.2E-19 T 10-11-2016 IPR006680 Amidohydrolase-related GO:0016787 A4G23_RS03560 92f2a7abbb5460ece194ed34a72f7342 437 SUPERFAMILY SSF51338 376 436 2.44E-19 T 10-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4G23_RS03560 92f2a7abbb5460ece194ed34a72f7342 437 SUPERFAMILY SSF51338 1 59 2.44E-19 T 10-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4G23_RS03560 92f2a7abbb5460ece194ed34a72f7342 437 ProSitePatterns PS00483 Dihydroorotase signature 2. 310 321 - T 10-11-2016 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 A4G23_RS09355 8f821c84bbf345d0d1d93452239595e1 316 Pfam PF00005 ABC transporter 30 173 1.6E-23 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS09355 8f821c84bbf345d0d1d93452239595e1 316 SUPERFAMILY SSF52540 23 236 2.47E-54 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS09355 8f821c84bbf345d0d1d93452239595e1 316 SMART SM00382 38 225 3.2E-11 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS09355 8f821c84bbf345d0d1d93452239595e1 316 Gene3D G3DSA:3.40.50.300 3 242 4.6E-60 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS08150 342983bdb1ee0d612dd547ac125e7104 200 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 109 143 1.2E-4 T 10-11-2016 IPR001451 Hexapeptide repeat A4G23_RS08150 342983bdb1ee0d612dd547ac125e7104 200 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 50 85 2.1E-6 T 10-11-2016 IPR001451 Hexapeptide repeat A4G23_RS08150 342983bdb1ee0d612dd547ac125e7104 200 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 15 48 1.2E-5 T 10-11-2016 IPR001451 Hexapeptide repeat A4G23_RS08150 342983bdb1ee0d612dd547ac125e7104 200 SUPERFAMILY SSF51161 4 162 4.85E-40 T 10-11-2016 IPR011004 Trimeric LpxA-like A4G23_RS08150 342983bdb1ee0d612dd547ac125e7104 200 Gene3D G3DSA:2.160.10.10 12 175 2.7E-37 T 10-11-2016 A4G23_RS19590 f68a5319d7bde25e5b29778e74fd1c98 620 Gene3D G3DSA:3.10.50.10 519 577 1.4E-23 T 10-11-2016 IPR029070 Chitinase insertion domain A4G23_RS19590 f68a5319d7bde25e5b29778e74fd1c98 620 SMART SM00060 154 228 5.1E-10 T 10-11-2016 IPR003961 Fibronectin type III GO:0005515 A4G23_RS19590 f68a5319d7bde25e5b29778e74fd1c98 620 Gene3D G3DSA:3.20.20.80 246 518 4.7E-83 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS19590 f68a5319d7bde25e5b29778e74fd1c98 620 Gene3D G3DSA:3.20.20.80 582 619 4.7E-83 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS19590 f68a5319d7bde25e5b29778e74fd1c98 620 Gene3D G3DSA:2.60.40.10 152 237 3.9E-22 T 10-11-2016 IPR013783 Immunoglobulin-like fold A4G23_RS19590 f68a5319d7bde25e5b29778e74fd1c98 620 SUPERFAMILY SSF51445 249 515 1.04E-79 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS19590 f68a5319d7bde25e5b29778e74fd1c98 620 SUPERFAMILY SSF51445 575 617 1.04E-79 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS19590 f68a5319d7bde25e5b29778e74fd1c98 620 SUPERFAMILY SSF49384 41 143 9.77E-33 T 10-11-2016 IPR008965 Carbohydrate-binding domain GO:0030246 A4G23_RS19590 f68a5319d7bde25e5b29778e74fd1c98 620 ProSitePatterns PS00561 CBM2a (carbohydrate-binding type-2) domain signature. 110 123 - T 10-11-2016 IPR018366 Carbohydrate-binding type-2, conserved site GO:0004553|GO:0005975|GO:0030246 A4G23_RS19590 f68a5319d7bde25e5b29778e74fd1c98 620 SMART SM00636 252 605 2.4E-112 T 10-11-2016 IPR011583 Chitinase II GO:0004568|GO:0006032 A4G23_RS19590 f68a5319d7bde25e5b29778e74fd1c98 620 ProSitePatterns PS01095 Chitinases family 18 active site. 386 394 - T 10-11-2016 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 A4G23_RS19590 f68a5319d7bde25e5b29778e74fd1c98 620 SUPERFAMILY SSF49265 152 237 7.62E-16 T 10-11-2016 IPR003961 Fibronectin type III GO:0005515 A4G23_RS19590 f68a5319d7bde25e5b29778e74fd1c98 620 Pfam PF00041 Fibronectin type III domain 155 230 8.6E-7 T 10-11-2016 IPR003961 Fibronectin type III GO:0005515 A4G23_RS19590 f68a5319d7bde25e5b29778e74fd1c98 620 SMART SM00637 45 142 1.1E-46 T 10-11-2016 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 A4G23_RS19590 f68a5319d7bde25e5b29778e74fd1c98 620 Gene3D G3DSA:2.60.40.290 44 144 2.4E-37 T 10-11-2016 IPR012291 Cellulose-binding family II/chitobiase, carbohydrate-binding domain GO:0004553|GO:0030247 A4G23_RS19590 f68a5319d7bde25e5b29778e74fd1c98 620 Pfam PF00553 Cellulose binding domain 45 142 1.8E-31 T 10-11-2016 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 A4G23_RS19590 f68a5319d7bde25e5b29778e74fd1c98 620 SUPERFAMILY SSF54556 517 576 2.51E-13 T 10-11-2016 IPR029070 Chitinase insertion domain A4G23_RS19590 f68a5319d7bde25e5b29778e74fd1c98 620 Pfam PF00704 Glycosyl hydrolases family 18 255 605 1.0E-71 T 10-11-2016 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0004553|GO:0005975 A4G23_RS19640 13d0169a26ae7e71024bbc4fc32803e1 344 Pfam PF00296 Luciferase-like monooxygenase 1 313 4.8E-54 T 10-11-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4G23_RS19640 13d0169a26ae7e71024bbc4fc32803e1 344 Gene3D G3DSA:3.20.20.30 1 344 2.7E-88 T 10-11-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4G23_RS19640 13d0169a26ae7e71024bbc4fc32803e1 344 SUPERFAMILY SSF51679 1 344 3.01E-70 T 10-11-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4G23_RS16075 fed8bf5aae39728e06b02a216d96bab3 841 TIGRFAM TIGR01973 NuoG: NADH dehydrogenase (quinone), G subunit 24 671 2.3E-188 T 10-11-2016 IPR010228 NADH:ubiquinone oxidoreductase, subunit G GO:0016651|GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16075 fed8bf5aae39728e06b02a216d96bab3 841 SMART SM00926 238 292 2.6E-7 T 10-11-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16075 fed8bf5aae39728e06b02a216d96bab3 841 ProSitePatterns PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. 168 178 - T 10-11-2016 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16075 fed8bf5aae39728e06b02a216d96bab3 841 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 107 144 4.8E-16 T 10-11-2016 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16075 fed8bf5aae39728e06b02a216d96bab3 841 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 120 132 - T 10-11-2016 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16075 fed8bf5aae39728e06b02a216d96bab3 841 Gene3D G3DSA:3.40.50.740 499 705 1.3E-38 T 10-11-2016 A4G23_RS16075 fed8bf5aae39728e06b02a216d96bab3 841 Gene3D G3DSA:3.40.50.740 295 365 1.3E-38 T 10-11-2016 A4G23_RS16075 fed8bf5aae39728e06b02a216d96bab3 841 Pfam PF00384 Molybdopterin oxidoreductase 566 654 3.4E-7 T 10-11-2016 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16075 fed8bf5aae39728e06b02a216d96bab3 841 Pfam PF00384 Molybdopterin oxidoreductase 295 440 6.6E-11 T 10-11-2016 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16075 fed8bf5aae39728e06b02a216d96bab3 841 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 20 95 5.9E-20 T 10-11-2016 A4G23_RS16075 fed8bf5aae39728e06b02a216d96bab3 841 Gene3D G3DSA:3.40.228.10 376 463 7.0E-4 T 10-11-2016 A4G23_RS16075 fed8bf5aae39728e06b02a216d96bab3 841 SUPERFAMILY SSF50692 735 815 3.25E-9 T 10-11-2016 IPR009010 Aspartate decarboxylase-like domain A4G23_RS16075 fed8bf5aae39728e06b02a216d96bab3 841 SUPERFAMILY SSF53706 242 699 3.87E-77 T 10-11-2016 A4G23_RS16075 fed8bf5aae39728e06b02a216d96bab3 841 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 242 289 3.3E-5 T 10-11-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16075 fed8bf5aae39728e06b02a216d96bab3 841 Gene3D G3DSA:3.30.70.20 159 225 6.8E-4 T 10-11-2016 A4G23_RS16075 fed8bf5aae39728e06b02a216d96bab3 841 SUPERFAMILY SSF54862 98 233 1.63E-30 T 10-11-2016 A4G23_RS16075 fed8bf5aae39728e06b02a216d96bab3 841 SUPERFAMILY SSF54292 22 94 3.71E-20 T 10-11-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A4G23_RS16075 fed8bf5aae39728e06b02a216d96bab3 841 SMART SM00929 105 145 2.0E-18 T 10-11-2016 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16075 fed8bf5aae39728e06b02a216d96bab3 841 Gene3D G3DSA:3.10.20.30 22 74 6.9E-7 T 10-11-2016 IPR012675 Beta-grasp domain A4G23_RS16075 fed8bf5aae39728e06b02a216d96bab3 841 Gene3D G3DSA:2.20.25.90 242 291 1.9E-11 T 10-11-2016 A4G23_RS16075 fed8bf5aae39728e06b02a216d96bab3 841 Pfam PF01568 Molydopterin dinucleotide binding domain 745 798 4.4E-8 T 10-11-2016 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 A4G23_RS16075 fed8bf5aae39728e06b02a216d96bab3 841 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 51 68 - T 10-11-2016 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16075 fed8bf5aae39728e06b02a216d96bab3 841 Gene3D G3DSA:2.40.40.20 740 795 3.9E-7 T 10-11-2016 A4G23_RS07375 dfa2e0eadd86f4761302249cdda3dfba 825 Pfam PF11202 Phosphoribosyl transferase (PRTase) 462 706 4.5E-106 T 10-11-2016 IPR011215 Phosphoribosyl transferase A4G23_RS07375 dfa2e0eadd86f4761302249cdda3dfba 825 SUPERFAMILY SSF53271 51 177 1.39E-7 T 10-11-2016 IPR029057 Phosphoribosyltransferase-like A4G23_RS07375 dfa2e0eadd86f4761302249cdda3dfba 825 Gene3D G3DSA:3.40.50.2020 43 202 1.5E-6 T 10-11-2016 IPR029057 Phosphoribosyltransferase-like A4G23_RS07375 dfa2e0eadd86f4761302249cdda3dfba 825 Pfam PF15608 PELOTA RNA binding domain 733 812 4.5E-34 T 10-11-2016 IPR028157 PELOTA RNA-binding domain A4G23_RS07375 dfa2e0eadd86f4761302249cdda3dfba 825 Pfam PF12500 TRSP domain C terminus to PRTase_2 250 429 1.3E-40 T 10-11-2016 IPR022537 TRSP domain A4G23_RS07375 dfa2e0eadd86f4761302249cdda3dfba 825 Pfam PF15609 Phosphoribosyl transferase 17 204 3.4E-68 T 10-11-2016 IPR029057 Phosphoribosyltransferase-like A4G23_RS01355 da67e6374a8c5b2cd1269d277c68415d 293 Gene3D G3DSA:3.20.20.150 1 292 1.2E-65 T 10-11-2016 IPR013022 Xylose isomerase-like, TIM barrel domain A4G23_RS01355 da67e6374a8c5b2cd1269d277c68415d 293 Pfam PF01261 Xylose isomerase-like TIM barrel 27 229 1.2E-28 T 10-11-2016 IPR013022 Xylose isomerase-like, TIM barrel domain A4G23_RS01355 da67e6374a8c5b2cd1269d277c68415d 293 SUPERFAMILY SSF51658 2 286 2.35E-47 T 10-11-2016 IPR013022 Xylose isomerase-like, TIM barrel domain A4G23_RS17085 0bb33a99ed50e3459cd16b75bcfd42d1 233 Gene3D G3DSA:3.40.50.2300 13 139 6.0E-25 T 10-11-2016 A4G23_RS17085 0bb33a99ed50e3459cd16b75bcfd42d1 233 Pfam PF00072 Response regulator receiver domain 19 136 6.3E-17 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS17085 0bb33a99ed50e3459cd16b75bcfd42d1 233 SUPERFAMILY SSF46894 163 232 2.01E-23 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS17085 0bb33a99ed50e3459cd16b75bcfd42d1 233 ProSitePatterns PS00622 LuxR-type HTH domain signature. 187 214 - T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS17085 0bb33a99ed50e3459cd16b75bcfd42d1 233 Gene3D G3DSA:1.10.10.10 140 233 6.3E-36 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS17085 0bb33a99ed50e3459cd16b75bcfd42d1 233 SUPERFAMILY SSF52172 16 154 1.85E-22 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS17085 0bb33a99ed50e3459cd16b75bcfd42d1 233 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 187 1.0E-14 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS17085 0bb33a99ed50e3459cd16b75bcfd42d1 233 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 203 215 1.0E-14 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS17085 0bb33a99ed50e3459cd16b75bcfd42d1 233 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 187 203 1.0E-14 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS17085 0bb33a99ed50e3459cd16b75bcfd42d1 233 Pfam PF00196 Bacterial regulatory proteins, luxR family 172 227 9.2E-21 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS17085 0bb33a99ed50e3459cd16b75bcfd42d1 233 SMART SM00421 170 227 6.0E-26 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS17085 0bb33a99ed50e3459cd16b75bcfd42d1 233 SMART SM00448 17 136 9.4E-18 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS13950 3b8385abe8fd179ec9c3a5ecc8875430 288 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 65 282 2.8E-33 T 10-11-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS13950 3b8385abe8fd179ec9c3a5ecc8875430 288 Gene3D G3DSA:1.10.601.10 51 137 1.4E-26 T 10-11-2016 A4G23_RS13950 3b8385abe8fd179ec9c3a5ecc8875430 288 PRINTS PR00046 Major sigma-70 factor signature 237 249 1.8E-8 T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS13950 3b8385abe8fd179ec9c3a5ecc8875430 288 PRINTS PR00046 Major sigma-70 factor signature 92 105 1.8E-8 T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS13950 3b8385abe8fd179ec9c3a5ecc8875430 288 PRINTS PR00046 Major sigma-70 factor signature 254 269 1.8E-8 T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS13950 3b8385abe8fd179ec9c3a5ecc8875430 288 SUPERFAMILY SSF88659 219 283 6.35E-15 T 10-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS13950 3b8385abe8fd179ec9c3a5ecc8875430 288 SUPERFAMILY SSF88946 36 138 2.22E-31 T 10-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS13950 3b8385abe8fd179ec9c3a5ecc8875430 288 Gene3D G3DSA:1.10.10.10 138 191 1.4E-20 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS13950 3b8385abe8fd179ec9c3a5ecc8875430 288 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 92 105 - T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS13950 3b8385abe8fd179ec9c3a5ecc8875430 288 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 62 283 4.5E-89 T 10-11-2016 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS13950 3b8385abe8fd179ec9c3a5ecc8875430 288 Pfam PF04539 Sigma-70 region 3 147 210 3.1E-15 T 10-11-2016 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS13950 3b8385abe8fd179ec9c3a5ecc8875430 288 Gene3D G3DSA:1.10.10.10 225 282 9.7E-10 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS13950 3b8385abe8fd179ec9c3a5ecc8875430 288 Pfam PF04542 Sigma-70 region 2 68 137 1.3E-18 T 10-11-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS13950 3b8385abe8fd179ec9c3a5ecc8875430 288 SUPERFAMILY SSF88659 141 214 1.77E-13 T 10-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS13950 3b8385abe8fd179ec9c3a5ecc8875430 288 Pfam PF04545 Sigma-70, region 4 234 281 5.0E-16 T 10-11-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS14740 14a0fd735f0802ccf273553ba85b7ede 191 Gene3D G3DSA:1.10.1740.10 34 103 7.0E-15 T 10-11-2016 A4G23_RS14740 14a0fd735f0802ccf273553ba85b7ede 191 Pfam PF08281 Sigma-70, region 4 130 183 1.3E-12 T 10-11-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS14740 14a0fd735f0802ccf273553ba85b7ede 191 SUPERFAMILY SSF88946 33 104 1.18E-14 T 10-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS14740 14a0fd735f0802ccf273553ba85b7ede 191 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 30 188 5.7E-57 T 10-11-2016 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 A4G23_RS14740 14a0fd735f0802ccf273553ba85b7ede 191 SUPERFAMILY SSF88659 114 187 7.66E-15 T 10-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS14740 14a0fd735f0802ccf273553ba85b7ede 191 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 35 186 1.8E-22 T 10-11-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS14740 14a0fd735f0802ccf273553ba85b7ede 191 Pfam PF04542 Sigma-70 region 2 39 103 2.4E-11 T 10-11-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS14740 14a0fd735f0802ccf273553ba85b7ede 191 Gene3D G3DSA:1.10.10.10 126 188 6.1E-16 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS24490 f1c341465bfd516ed945ec429f51df7b 308 SUPERFAMILY SSF53850 89 303 4.98E-37 T 10-11-2016 A4G23_RS24490 f1c341465bfd516ed945ec429f51df7b 308 Gene3D G3DSA:3.40.190.10 182 269 6.6E-27 T 10-11-2016 A4G23_RS24490 f1c341465bfd516ed945ec429f51df7b 308 SUPERFAMILY SSF46785 2 112 2.04E-23 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS24490 f1c341465bfd516ed945ec429f51df7b 308 Gene3D G3DSA:1.10.10.10 2 88 6.3E-27 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS24490 f1c341465bfd516ed945ec429f51df7b 308 Gene3D G3DSA:3.40.190.10 89 181 6.0E-16 T 10-11-2016 A4G23_RS24490 f1c341465bfd516ed945ec429f51df7b 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 2.4E-20 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS24490 f1c341465bfd516ed945ec429f51df7b 308 Pfam PF03466 LysR substrate binding domain 88 298 2.3E-37 T 10-11-2016 IPR005119 LysR, substrate-binding A4G23_RS14970 c3e7812cbf04793d33b1e7665828c018 954 Gene3D G3DSA:1.10.460.10 501 595 1.4E-49 T 10-11-2016 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 A4G23_RS14970 c3e7812cbf04793d33b1e7665828c018 954 Gene3D G3DSA:1.10.460.10 156 203 1.4E-49 T 10-11-2016 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 A4G23_RS14970 c3e7812cbf04793d33b1e7665828c018 954 Hamap MF_00952 DNA topoisomerase 1 [topA]. 12 780 55.094 T 10-11-2016 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 A4G23_RS14970 c3e7812cbf04793d33b1e7665828c018 954 Gene3D G3DSA:2.70.20.10 205 353 4.0E-26 T 10-11-2016 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 A4G23_RS14970 c3e7812cbf04793d33b1e7665828c018 954 Gene3D G3DSA:2.70.20.10 354 500 1.6E-34 T 10-11-2016 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 A4G23_RS14970 c3e7812cbf04793d33b1e7665828c018 954 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 329 338 2.1E-33 T 10-11-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 A4G23_RS14970 c3e7812cbf04793d33b1e7665828c018 954 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 406 422 2.1E-33 T 10-11-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 A4G23_RS14970 c3e7812cbf04793d33b1e7665828c018 954 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 183 201 2.1E-33 T 10-11-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 A4G23_RS14970 c3e7812cbf04793d33b1e7665828c018 954 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 99 112 2.1E-33 T 10-11-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 A4G23_RS14970 c3e7812cbf04793d33b1e7665828c018 954 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 517 531 2.1E-33 T 10-11-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 A4G23_RS14970 c3e7812cbf04793d33b1e7665828c018 954 Pfam PF01751 Toprim domain 14 134 1.7E-27 T 10-11-2016 IPR006171 Toprim domain A4G23_RS14970 c3e7812cbf04793d33b1e7665828c018 954 SUPERFAMILY SSF56712 12 595 2.35E-178 T 10-11-2016 IPR023405 DNA topoisomerase, type IA, core domain A4G23_RS14970 c3e7812cbf04793d33b1e7665828c018 954 SMART SM00437 287 554 2.0E-121 T 10-11-2016 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 A4G23_RS14970 c3e7812cbf04793d33b1e7665828c018 954 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 324 338 - T 10-11-2016 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 A4G23_RS14970 c3e7812cbf04793d33b1e7665828c018 954 Pfam PF13368 Topoisomerase C-terminal repeat 701 765 2.0E-14 T 10-11-2016 IPR025589 Topoisomerase C-terminal repeat A4G23_RS14970 c3e7812cbf04793d33b1e7665828c018 954 Pfam PF13368 Topoisomerase C-terminal repeat 642 693 1.2E-6 T 10-11-2016 IPR025589 Topoisomerase C-terminal repeat A4G23_RS14970 c3e7812cbf04793d33b1e7665828c018 954 Pfam PF13368 Topoisomerase C-terminal repeat 771 821 9.4E-15 T 10-11-2016 IPR025589 Topoisomerase C-terminal repeat A4G23_RS14970 c3e7812cbf04793d33b1e7665828c018 954 Pfam PF13368 Topoisomerase C-terminal repeat 834 886 1.1E-19 T 10-11-2016 IPR025589 Topoisomerase C-terminal repeat A4G23_RS14970 c3e7812cbf04793d33b1e7665828c018 954 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 14 660 7.9E-240 T 10-11-2016 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 A4G23_RS14970 c3e7812cbf04793d33b1e7665828c018 954 Pfam PF01131 DNA topoisomerase 149 591 2.6E-129 T 10-11-2016 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A4G23_RS14970 c3e7812cbf04793d33b1e7665828c018 954 Gene3D G3DSA:3.40.50.140 12 155 2.4E-48 T 10-11-2016 IPR006171 Toprim domain A4G23_RS14970 c3e7812cbf04793d33b1e7665828c018 954 SMART SM00493 12 125 5.3E-35 T 10-11-2016 IPR006171 Toprim domain A4G23_RS14970 c3e7812cbf04793d33b1e7665828c018 954 SMART SM00436 125 213 1.9E-43 T 10-11-2016 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 A4G23_RS17585 e12caac92ee3c0742b14942ef007ecad 513 ProSitePatterns PS00211 ABC transporters family signature. 399 413 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS17585 e12caac92ee3c0742b14942ef007ecad 513 Gene3D G3DSA:3.40.50.300 248 491 1.3E-45 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS17585 e12caac92ee3c0742b14942ef007ecad 513 Gene3D G3DSA:3.40.50.300 1 223 5.8E-57 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS17585 e12caac92ee3c0742b14942ef007ecad 513 Pfam PF00005 ABC transporter 272 426 9.9E-16 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS17585 e12caac92ee3c0742b14942ef007ecad 513 Pfam PF00005 ABC transporter 17 162 1.0E-27 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS17585 e12caac92ee3c0742b14942ef007ecad 513 SUPERFAMILY SSF52540 2 219 6.88E-54 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS17585 e12caac92ee3c0742b14942ef007ecad 513 SUPERFAMILY SSF52540 248 485 1.41E-42 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS17585 e12caac92ee3c0742b14942ef007ecad 513 SMART SM00382 25 210 3.8E-12 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS17585 e12caac92ee3c0742b14942ef007ecad 513 SMART SM00382 279 475 3.1 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS02475 58ba59fb6586eb360940e91c8b5eae9b 216 Gene3D G3DSA:1.10.357.10 2 204 1.7E-47 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS02475 58ba59fb6586eb360940e91c8b5eae9b 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 4.8E-6 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS02475 58ba59fb6586eb360940e91c8b5eae9b 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 4.8E-6 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS02475 58ba59fb6586eb360940e91c8b5eae9b 216 SUPERFAMILY SSF48498 87 204 3.78E-17 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS02475 58ba59fb6586eb360940e91c8b5eae9b 216 SUPERFAMILY SSF46689 8 84 8.48E-19 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS02475 58ba59fb6586eb360940e91c8b5eae9b 216 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 5.3E-11 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS02475 58ba59fb6586eb360940e91c8b5eae9b 216 ProSitePatterns PS01081 TetR-type HTH domain signature. 32 61 - T 10-11-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A4G23_RS05150 717d2d8a88e61342aa9e5dfa66a12648 507 Pfam PF01523 Putative modulator of DNA gyrase 32 347 2.5E-50 T 10-11-2016 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 A4G23_RS05150 717d2d8a88e61342aa9e5dfa66a12648 507 SUPERFAMILY SSF111283 12 498 9.16E-96 T 10-11-2016 A4G23_RS05195 3264de85f77756f976fa1b8baf102154 510 SUPERFAMILY SSF52743 359 509 1.11E-77 T 10-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4G23_RS05195 3264de85f77756f976fa1b8baf102154 510 SUPERFAMILY SSF52743 153 332 1.11E-77 T 10-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4G23_RS05195 3264de85f77756f976fa1b8baf102154 510 Gene3D G3DSA:3.40.50.200 145 509 2.6E-81 T 10-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4G23_RS05195 3264de85f77756f976fa1b8baf102154 510 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 178 189 - T 10-11-2016 IPR023827 Peptidase S8, subtilisin, Asp-active site A4G23_RS05195 3264de85f77756f976fa1b8baf102154 510 PRINTS PR00723 Subtilisin serine protease family (S8) signature 221 234 8.2E-20 T 10-11-2016 IPR015500 Peptidase S8, subtilisin-related A4G23_RS05195 3264de85f77756f976fa1b8baf102154 510 PRINTS PR00723 Subtilisin serine protease family (S8) signature 430 446 8.2E-20 T 10-11-2016 IPR015500 Peptidase S8, subtilisin-related A4G23_RS05195 3264de85f77756f976fa1b8baf102154 510 PRINTS PR00723 Subtilisin serine protease family (S8) signature 173 192 8.2E-20 T 10-11-2016 IPR015500 Peptidase S8, subtilisin-related A4G23_RS05195 3264de85f77756f976fa1b8baf102154 510 Pfam PF00082 Subtilase family 174 467 7.5E-46 T 10-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4G23_RS05195 3264de85f77756f976fa1b8baf102154 510 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 431 441 - T 10-11-2016 IPR023828 Peptidase S8, subtilisin, Ser-active site A4G23_RS05195 3264de85f77756f976fa1b8baf102154 510 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 225 235 - T 10-11-2016 IPR022398 Peptidase S8, subtilisin, His-active site A4G23_RS17960 fe941eb529f0cccad84818d8a27fd651 289 Pfam PF01061 ABC-2 type transporter 31 245 5.7E-28 T 10-11-2016 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A4G23_RS17960 fe941eb529f0cccad84818d8a27fd651 289 PIRSF PIRSF006648 2 289 9.7E-72 T 10-11-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 A4G23_RS23785 14044f4175cee4e622f486207aa6c7dd 306 SUPERFAMILY SSF46785 3 84 1.04E-21 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS23785 14044f4175cee4e622f486207aa6c7dd 306 Gene3D G3DSA:3.40.190.10 100 187 6.3E-8 T 10-11-2016 A4G23_RS23785 14044f4175cee4e622f486207aa6c7dd 306 Gene3D G3DSA:3.40.190.10 188 265 2.3E-7 T 10-11-2016 A4G23_RS23785 14044f4175cee4e622f486207aa6c7dd 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 1.0E-8 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS23785 14044f4175cee4e622f486207aa6c7dd 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 1.0E-8 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS23785 14044f4175cee4e622f486207aa6c7dd 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 1.0E-8 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS23785 14044f4175cee4e622f486207aa6c7dd 306 SUPERFAMILY SSF53850 94 300 3.62E-14 T 10-11-2016 A4G23_RS23785 14044f4175cee4e622f486207aa6c7dd 306 Pfam PF03466 LysR substrate binding domain 96 296 4.3E-13 T 10-11-2016 IPR005119 LysR, substrate-binding A4G23_RS23785 14044f4175cee4e622f486207aa6c7dd 306 Gene3D G3DSA:1.10.10.10 3 88 9.8E-25 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS23785 14044f4175cee4e622f486207aa6c7dd 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 1.1E-20 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS12950 75e6fb4f2606b904983b5a705fb3fee0 300 Pfam PF01259 SAICAR synthetase 18 270 3.5E-103 T 10-11-2016 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4G23_RS12950 75e6fb4f2606b904983b5a705fb3fee0 300 ProSitePatterns PS01058 SAICAR synthetase signature 2. 204 212 - T 10-11-2016 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4G23_RS12950 75e6fb4f2606b904983b5a705fb3fee0 300 Gene3D G3DSA:3.30.200.20 12 115 4.9E-43 T 10-11-2016 A4G23_RS12950 75e6fb4f2606b904983b5a705fb3fee0 300 ProSitePatterns PS01057 SAICAR synthetase signature 1. 105 119 - T 10-11-2016 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4G23_RS12950 75e6fb4f2606b904983b5a705fb3fee0 300 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 16 296 26.068 T 10-11-2016 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4G23_RS12950 75e6fb4f2606b904983b5a705fb3fee0 300 SUPERFAMILY SSF56104 13 299 4.58E-100 T 10-11-2016 A4G23_RS12950 75e6fb4f2606b904983b5a705fb3fee0 300 Gene3D G3DSA:3.30.470.20 116 248 8.9E-56 T 10-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 A4G23_RS12950 75e6fb4f2606b904983b5a705fb3fee0 300 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 19 299 2.4E-74 T 10-11-2016 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 A4G23_RS17700 6275b118d70a26a28b18dae6b9c3ed99 308 Gene3D G3DSA:3.20.20.70 40 300 4.6E-95 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS17700 6275b118d70a26a28b18dae6b9c3ed99 308 SUPERFAMILY SSF51569 47 288 1.99E-74 T 10-11-2016 A4G23_RS17700 6275b118d70a26a28b18dae6b9c3ed99 308 Pfam PF01791 DeoC/LacD family aldolase 42 286 1.9E-27 T 10-11-2016 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-71336 A4G23_RS17700 6275b118d70a26a28b18dae6b9c3ed99 308 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 49 271 8.0E-55 T 10-11-2016 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-71336 A4G23_RS17700 6275b118d70a26a28b18dae6b9c3ed99 308 PIRSF PIRSF001357 40 298 1.4E-84 T 10-11-2016 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-71336 A4G23_RS17700 6275b118d70a26a28b18dae6b9c3ed99 308 SMART SM01133 46 289 4.6E-74 T 10-11-2016 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-71336 A4G23_RS04745 340548b140197efcf8dab29f1b000358 1194 Gene3D G3DSA:3.20.20.140 6 73 2.6E-8 T 10-11-2016 A4G23_RS04745 340548b140197efcf8dab29f1b000358 1194 Gene3D G3DSA:2.40.50.140 999 1077 3.1E-4 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS04745 340548b140197efcf8dab29f1b000358 1194 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 4 1049 5.8E-152 T 10-11-2016 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4G23_RS04745 340548b140197efcf8dab29f1b000358 1194 SMART SM00481 5 72 3.5E-22 T 10-11-2016 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 A4G23_RS04745 340548b140197efcf8dab29f1b000358 1194 Pfam PF14579 Helix-hairpin-helix motif 829 926 1.1E-17 T 10-11-2016 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4G23_RS04745 340548b140197efcf8dab29f1b000358 1194 SUPERFAMILY SSF89550 6 67 3.53E-8 T 10-11-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A4G23_RS04745 340548b140197efcf8dab29f1b000358 1194 Pfam PF02811 PHP domain 6 187 2.1E-16 T 10-11-2016 IPR004013 PHP domain GO:0003824 A4G23_RS04745 340548b140197efcf8dab29f1b000358 1194 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 335 755 3.3E-124 T 10-11-2016 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4G23_RS05070 acf831e6e1d5b0aad4a9cba88d544970 381 SUPERFAMILY SSF55781 11 179 6.54E-31 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS05070 acf831e6e1d5b0aad4a9cba88d544970 381 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 289 379 4.5E-9 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS05070 acf831e6e1d5b0aad4a9cba88d544970 381 Pfam PF07730 Histidine kinase 183 250 9.4E-18 T 10-11-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4G23_RS05070 acf831e6e1d5b0aad4a9cba88d544970 381 Gene3D G3DSA:3.30.450.40 18 174 1.0E-30 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS05070 acf831e6e1d5b0aad4a9cba88d544970 381 SMART SM00387 287 381 6.3E-12 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS05070 acf831e6e1d5b0aad4a9cba88d544970 381 Gene3D G3DSA:3.30.565.10 272 379 4.4E-14 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS05070 acf831e6e1d5b0aad4a9cba88d544970 381 Pfam PF13185 GAF domain 23 166 2.4E-21 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS05070 acf831e6e1d5b0aad4a9cba88d544970 381 PRINTS PR00344 Bacterial sensor protein C-terminal signature 323 337 1.2E-5 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS05070 acf831e6e1d5b0aad4a9cba88d544970 381 PRINTS PR00344 Bacterial sensor protein C-terminal signature 366 379 1.2E-5 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS05070 acf831e6e1d5b0aad4a9cba88d544970 381 PRINTS PR00344 Bacterial sensor protein C-terminal signature 342 360 1.2E-5 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS05070 acf831e6e1d5b0aad4a9cba88d544970 381 SUPERFAMILY SSF55874 253 379 1.17E-20 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS05070 acf831e6e1d5b0aad4a9cba88d544970 381 SMART SM00065 24 176 1.2E-18 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS23320 28b1ec723508df6c5e3fd425b0573e54 323 PRINTS PR00990 Ribokinase signature 224 235 3.8E-8 T 10-11-2016 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 A4G23_RS23320 28b1ec723508df6c5e3fd425b0573e54 323 PRINTS PR00990 Ribokinase signature 33 52 3.8E-8 T 10-11-2016 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 A4G23_RS23320 28b1ec723508df6c5e3fd425b0573e54 323 PRINTS PR00990 Ribokinase signature 185 200 3.8E-8 T 10-11-2016 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 A4G23_RS23320 28b1ec723508df6c5e3fd425b0573e54 323 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 253 266 - T 10-11-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A4G23_RS23320 28b1ec723508df6c5e3fd425b0573e54 323 Gene3D G3DSA:3.40.1190.20 1 313 2.2E-66 T 10-11-2016 IPR029056 Ribokinase-like A4G23_RS23320 28b1ec723508df6c5e3fd425b0573e54 323 Pfam PF00294 pfkB family carbohydrate kinase 4 309 2.4E-45 T 10-11-2016 IPR011611 Carbohydrate kinase PfkB A4G23_RS23320 28b1ec723508df6c5e3fd425b0573e54 323 SUPERFAMILY SSF53613 3 311 6.08E-64 T 10-11-2016 IPR029056 Ribokinase-like A4G23_RS19575 c56a30ce4c2e26ea03f662c1300f5fbe 480 SUPERFAMILY SSF52540 92 364 7.88E-86 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS19575 c56a30ce4c2e26ea03f662c1300f5fbe 480 Hamap MF_01347 ATP synthase subunit beta [atpB]. 9 477 54.081 T 10-11-2016 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201 A4G23_RS19575 c56a30ce4c2e26ea03f662c1300f5fbe 480 Gene3D G3DSA:1.10.1140.10 362 477 3.9E-43 T 10-11-2016 IPR024034 ATPase, F1 complex beta subunit/V1 complex, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A4G23_RS19575 c56a30ce4c2e26ea03f662c1300f5fbe 480 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 11 477 4.9E-235 T 10-11-2016 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201 A4G23_RS19575 c56a30ce4c2e26ea03f662c1300f5fbe 480 Gene3D G3DSA:2.40.10.170 4 89 1.3E-30 T 10-11-2016 A4G23_RS19575 c56a30ce4c2e26ea03f662c1300f5fbe 480 Gene3D G3DSA:3.40.50.300 92 361 3.8E-102 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS19575 c56a30ce4c2e26ea03f662c1300f5fbe 480 SUPERFAMILY SSF50615 10 89 6.02E-26 T 10-11-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A4G23_RS19575 c56a30ce4c2e26ea03f662c1300f5fbe 480 SMART SM00382 158 344 0.0066 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS19575 c56a30ce4c2e26ea03f662c1300f5fbe 480 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 146 359 3.9E-64 T 10-11-2016 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A4G23_RS19575 c56a30ce4c2e26ea03f662c1300f5fbe 480 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 14 88 2.7E-22 T 10-11-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A4G23_RS19575 c56a30ce4c2e26ea03f662c1300f5fbe 480 SUPERFAMILY SSF47917 362 476 6.02E-45 T 10-11-2016 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A4G23_RS19575 c56a30ce4c2e26ea03f662c1300f5fbe 480 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 350 359 - T 10-11-2016 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A4G23_RS16965 5c33c746bc378e94ce6476c2c0ad1025 201 SUPERFAMILY SSF88946 20 122 4.51E-15 T 10-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS16965 5c33c746bc378e94ce6476c2c0ad1025 201 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 33 196 4.4E-23 T 10-11-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS16965 5c33c746bc378e94ce6476c2c0ad1025 201 Pfam PF04545 Sigma-70, region 4 148 197 3.7E-12 T 10-11-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS16965 5c33c746bc378e94ce6476c2c0ad1025 201 PRINTS PR00046 Major sigma-70 factor signature 169 184 5.8E-5 T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS16965 5c33c746bc378e94ce6476c2c0ad1025 201 PRINTS PR00046 Major sigma-70 factor signature 66 79 5.8E-5 T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS16965 5c33c746bc378e94ce6476c2c0ad1025 201 PRINTS PR00046 Major sigma-70 factor signature 184 195 5.8E-5 T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS16965 5c33c746bc378e94ce6476c2c0ad1025 201 PRINTS PR00046 Major sigma-70 factor signature 152 164 5.8E-5 T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS16965 5c33c746bc378e94ce6476c2c0ad1025 201 Gene3D G3DSA:1.10.1740.10 21 135 1.9E-15 T 10-11-2016 A4G23_RS16965 5c33c746bc378e94ce6476c2c0ad1025 201 SUPERFAMILY SSF88659 126 198 1.05E-14 T 10-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS16965 5c33c746bc378e94ce6476c2c0ad1025 201 Gene3D G3DSA:1.10.10.10 141 198 3.5E-14 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS16965 5c33c746bc378e94ce6476c2c0ad1025 201 Pfam PF04542 Sigma-70 region 2 37 108 1.3E-9 T 10-11-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS22825 db3f062e49db2e7edf9c6379b4f68e18 254 TIGRFAM TIGR01868 casD_Cas5e: CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI 3 223 5.2E-40 T 10-11-2016 IPR010147 CRISPR-associated protein, CasD GO:0003723|GO:0051607 A4G23_RS22825 db3f062e49db2e7edf9c6379b4f68e18 254 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 4 223 8.9E-50 T 10-11-2016 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 A4G23_RS22825 db3f062e49db2e7edf9c6379b4f68e18 254 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 3 42 1.1E-8 T 10-11-2016 IPR013422 CRISPR-associated protein Cas5, N-terminal A4G23_RS15240 e8b57e2ca0aee0acef701fac3da9eb55 550 Pfam PF12821 Threonine/Serine exporter, ThrE 399 523 1.2E-16 T 10-11-2016 IPR024528 Threonine/Serine exporter, ThrE A4G23_RS15240 e8b57e2ca0aee0acef701fac3da9eb55 550 Pfam PF06738 Putative threonine/serine exporter 132 375 9.1E-63 T 10-11-2016 IPR010619 Putative threonine/serine exporter A4G23_RS01885 3210726d93ebf6c58655ad064b21fd9d 203 Pfam PF01872 RibD C-terminal domain 3 173 1.6E-8 T 10-11-2016 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 A4G23_RS01885 3210726d93ebf6c58655ad064b21fd9d 203 Gene3D G3DSA:3.40.430.10 3 201 1.8E-23 T 10-11-2016 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 A4G23_RS01885 3210726d93ebf6c58655ad064b21fd9d 203 SUPERFAMILY SSF53597 1 200 2.66E-18 T 10-11-2016 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 A4G23_RS26420 babd0adfac6f2bf6ff9091b88ed2bf9d 797 Pfam PF00005 ABC transporter 507 714 1.5E-10 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS26420 babd0adfac6f2bf6ff9091b88ed2bf9d 797 Gene3D G3DSA:1.20.1580.10 301 366 6.0E-30 T 10-11-2016 A4G23_RS26420 babd0adfac6f2bf6ff9091b88ed2bf9d 797 Gene3D G3DSA:1.20.1580.10 112 186 6.0E-30 T 10-11-2016 A4G23_RS26420 babd0adfac6f2bf6ff9091b88ed2bf9d 797 SUPERFAMILY SSF52540 499 767 6.23E-38 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS26420 babd0adfac6f2bf6ff9091b88ed2bf9d 797 Gene3D G3DSA:1.10.8.280 188 300 7.0E-8 T 10-11-2016 A4G23_RS26420 babd0adfac6f2bf6ff9091b88ed2bf9d 797 Gene3D G3DSA:3.40.50.300 367 483 5.6E-53 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS26420 babd0adfac6f2bf6ff9091b88ed2bf9d 797 Gene3D G3DSA:3.40.50.300 492 551 2.7E-55 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS26420 babd0adfac6f2bf6ff9091b88ed2bf9d 797 Gene3D G3DSA:3.40.50.300 678 793 2.7E-55 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS26420 babd0adfac6f2bf6ff9091b88ed2bf9d 797 Gene3D G3DSA:3.40.50.300 11 76 5.6E-53 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS26420 babd0adfac6f2bf6ff9091b88ed2bf9d 797 SUPERFAMILY SSF52540 328 458 2.14E-31 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS26420 babd0adfac6f2bf6ff9091b88ed2bf9d 797 SUPERFAMILY SSF52540 23 71 2.14E-31 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS26420 babd0adfac6f2bf6ff9091b88ed2bf9d 797 Gene3D G3DSA:1.20.1580.10 555 677 8.1E-36 T 10-11-2016 A4G23_RS04095 0d7613906c3cdca4a53f4fe52288f12b 842 Pfam PF03483 B3/4 domain 221 405 2.0E-65 T 10-11-2016 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 A4G23_RS04095 0d7613906c3cdca4a53f4fe52288f12b 842 Gene3D G3DSA:3.30.56.10 164 193 5.1E-18 T 10-11-2016 A4G23_RS04095 0d7613906c3cdca4a53f4fe52288f12b 842 Gene3D G3DSA:3.30.56.10 1 40 5.1E-18 T 10-11-2016 A4G23_RS04095 0d7613906c3cdca4a53f4fe52288f12b 842 SUPERFAMILY SSF46955 421 492 5.49E-15 T 10-11-2016 IPR009061 Putative DNA-binding domain A4G23_RS04095 0d7613906c3cdca4a53f4fe52288f12b 842 Gene3D G3DSA:3.50.40.10 208 414 7.3E-81 T 10-11-2016 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 Reactome: R-HSA-379716 A4G23_RS04095 0d7613906c3cdca4a53f4fe52288f12b 842 SUPERFAMILY SSF54991 744 840 1.57E-26 T 10-11-2016 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 A4G23_RS04095 0d7613906c3cdca4a53f4fe52288f12b 842 SMART SM00874 421 488 2.2E-20 T 10-11-2016 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 A4G23_RS04095 0d7613906c3cdca4a53f4fe52288f12b 842 SUPERFAMILY SSF50249 47 205 2.86E-32 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS04095 0d7613906c3cdca4a53f4fe52288f12b 842 Gene3D G3DSA:2.40.50.140 45 162 3.5E-39 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS04095 0d7613906c3cdca4a53f4fe52288f12b 842 Gene3D G3DSA:3.30.56.20 420 492 1.5E-21 T 10-11-2016 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 A4G23_RS04095 0d7613906c3cdca4a53f4fe52288f12b 842 Pfam PF03147 Ferredoxin-fold anticodon binding domain 747 840 5.3E-24 T 10-11-2016 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 A4G23_RS04095 0d7613906c3cdca4a53f4fe52288f12b 842 Pfam PF03484 tRNA synthetase B5 domain 424 488 5.9E-16 T 10-11-2016 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 A4G23_RS04095 0d7613906c3cdca4a53f4fe52288f12b 842 Pfam PF01588 Putative tRNA binding domain 48 154 4.9E-20 T 10-11-2016 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 A4G23_RS04095 0d7613906c3cdca4a53f4fe52288f12b 842 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 840 7.9E-185 T 10-11-2016 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 A4G23_RS04095 0d7613906c3cdca4a53f4fe52288f12b 842 SUPERFAMILY SSF56037 205 413 2.88E-63 T 10-11-2016 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 Reactome: R-HSA-379716 A4G23_RS04095 0d7613906c3cdca4a53f4fe52288f12b 842 SMART SM00896 747 840 6.4E-42 T 10-11-2016 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 A4G23_RS04095 0d7613906c3cdca4a53f4fe52288f12b 842 SUPERFAMILY SSF55681 484 600 3.03E-42 T 10-11-2016 A4G23_RS04095 0d7613906c3cdca4a53f4fe52288f12b 842 SUPERFAMILY SSF55681 630 732 3.03E-42 T 10-11-2016 A4G23_RS04095 0d7613906c3cdca4a53f4fe52288f12b 842 Gene3D G3DSA:3.30.930.10 503 733 2.7E-64 T 10-11-2016 A4G23_RS04095 0d7613906c3cdca4a53f4fe52288f12b 842 SMART SM00873 221 405 4.2E-81 T 10-11-2016 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 A4G23_RS04095 0d7613906c3cdca4a53f4fe52288f12b 842 Gene3D G3DSA:3.30.70.380 749 840 2.1E-29 T 10-11-2016 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 A4G23_RS04095 0d7613906c3cdca4a53f4fe52288f12b 842 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 834 40.28 T 10-11-2016 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 A4G23_RS05255 aade1912bdc009af42a1bf4ea9e3f03f 532 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS05255 aade1912bdc009af42a1bf4ea9e3f03f 532 ProSitePatterns PS00211 ABC transporters family signature. 443 457 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS05255 aade1912bdc009af42a1bf4ea9e3f03f 532 SUPERFAMILY SSF52540 330 517 8.18E-48 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05255 aade1912bdc009af42a1bf4ea9e3f03f 532 Pfam PF00005 ABC transporter 342 471 2.5E-25 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS05255 aade1912bdc009af42a1bf4ea9e3f03f 532 Pfam PF00005 ABC transporter 19 187 1.2E-24 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS05255 aade1912bdc009af42a1bf4ea9e3f03f 532 Gene3D G3DSA:3.40.50.300 5 98 2.3E-45 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05255 aade1912bdc009af42a1bf4ea9e3f03f 532 Gene3D G3DSA:3.40.50.300 327 516 3.1E-44 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05255 aade1912bdc009af42a1bf4ea9e3f03f 532 Gene3D G3DSA:3.40.50.300 135 282 2.3E-45 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05255 aade1912bdc009af42a1bf4ea9e3f03f 532 Pfam PF12848 ABC transporter 231 304 1.6E-6 T 10-11-2016 IPR032781 ABC-transporter extension domain A4G23_RS05255 aade1912bdc009af42a1bf4ea9e3f03f 532 SMART SM00382 26 232 2.1E-10 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS05255 aade1912bdc009af42a1bf4ea9e3f03f 532 SMART SM00382 350 515 8.4E-10 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS05255 aade1912bdc009af42a1bf4ea9e3f03f 532 SUPERFAMILY SSF52540 2 79 2.52E-44 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05255 aade1912bdc009af42a1bf4ea9e3f03f 532 SUPERFAMILY SSF52540 128 234 2.52E-44 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05625 436c7c01bc0042c39fe60cca067aa38f 507 SUPERFAMILY SSF55347 198 505 1.01E-115 T 10-11-2016 A4G23_RS05625 436c7c01bc0042c39fe60cca067aa38f 507 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 210 505 1.1E-115 T 10-11-2016 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A4G23_RS05625 436c7c01bc0042c39fe60cca067aa38f 507 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 25 208 1.4E-63 T 10-11-2016 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A4G23_RS05625 436c7c01bc0042c39fe60cca067aa38f 507 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 198 204 - T 10-11-2016 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A4G23_RS05625 436c7c01bc0042c39fe60cca067aa38f 507 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 21 506 89.119 T 10-11-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A4G23_RS05625 436c7c01bc0042c39fe60cca067aa38f 507 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 23 506 4.3E-204 T 10-11-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A4G23_RS05625 436c7c01bc0042c39fe60cca067aa38f 507 SUPERFAMILY SSF51735 11 211 1.0E-62 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS05625 436c7c01bc0042c39fe60cca067aa38f 507 Gene3D G3DSA:3.30.360.10 208 505 5.4E-123 T 10-11-2016 A4G23_RS05625 436c7c01bc0042c39fe60cca067aa38f 507 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 240 257 2.6E-48 T 10-11-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A4G23_RS05625 436c7c01bc0042c39fe60cca067aa38f 507 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 347 373 2.6E-48 T 10-11-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A4G23_RS05625 436c7c01bc0042c39fe60cca067aa38f 507 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 188 216 2.6E-48 T 10-11-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A4G23_RS05625 436c7c01bc0042c39fe60cca067aa38f 507 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 258 274 2.6E-48 T 10-11-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A4G23_RS05625 436c7c01bc0042c39fe60cca067aa38f 507 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 164 177 2.6E-48 T 10-11-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A4G23_RS05625 436c7c01bc0042c39fe60cca067aa38f 507 PIRSF PIRSF000110 8 507 3.3E-182 T 10-11-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A4G23_RS05625 436c7c01bc0042c39fe60cca067aa38f 507 Gene3D G3DSA:3.40.50.720 21 207 3.0E-69 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS22640 bc73ccdc7cde42d656f0ca10a99e3910 202 SUPERFAMILY SSF54631 37 165 3.32E-20 T 10-11-2016 A4G23_RS22640 bc73ccdc7cde42d656f0ca10a99e3910 202 Pfam PF00571 CBS domain 115 163 2.6E-7 T 10-11-2016 IPR000644 CBS domain A4G23_RS22640 bc73ccdc7cde42d656f0ca10a99e3910 202 Pfam PF00571 CBS domain 41 91 1.0E-6 T 10-11-2016 IPR000644 CBS domain A4G23_RS22640 bc73ccdc7cde42d656f0ca10a99e3910 202 SMART SM00116 115 163 2.6E-8 T 10-11-2016 IPR000644 CBS domain A4G23_RS22640 bc73ccdc7cde42d656f0ca10a99e3910 202 SMART SM00116 48 96 0.35 T 10-11-2016 IPR000644 CBS domain A4G23_RS22640 bc73ccdc7cde42d656f0ca10a99e3910 202 Gene3D G3DSA:3.10.580.10 41 164 6.4E-19 T 10-11-2016 A4G23_RS02450 f7c9ea40b9b69cabc22dbc708286649b 538 Gene3D G3DSA:3.90.400.10 105 182 4.0E-26 T 10-11-2016 A4G23_RS02450 f7c9ea40b9b69cabc22dbc708286649b 538 Pfam PF11941 Domain of unknown function (DUF3459) 458 534 4.9E-6 T 10-11-2016 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) A4G23_RS02450 f7c9ea40b9b69cabc22dbc708286649b 538 Gene3D G3DSA:3.20.20.80 183 472 5.2E-103 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS02450 f7c9ea40b9b69cabc22dbc708286649b 538 Gene3D G3DSA:3.20.20.80 3 104 5.2E-103 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS02450 f7c9ea40b9b69cabc22dbc708286649b 538 Pfam PF00128 Alpha amylase, catalytic domain 28 382 2.1E-82 T 10-11-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A4G23_RS02450 f7c9ea40b9b69cabc22dbc708286649b 538 SUPERFAMILY SSF51445 4 472 8.45E-120 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS02450 f7c9ea40b9b69cabc22dbc708286649b 538 SMART SM00642 13 406 1.6E-119 T 10-11-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A4G23_RS19600 f6a2fd628e72b94e1eedca319c266bbd 402 Gene3D G3DSA:3.30.565.10 266 376 6.2E-4 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS19600 f6a2fd628e72b94e1eedca319c266bbd 402 SUPERFAMILY SSF55874 266 374 3.72E-10 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS19600 f6a2fd628e72b94e1eedca319c266bbd 402 Pfam PF07730 Histidine kinase 186 248 3.1E-13 T 10-11-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4G23_RS26025 b73748e98aec66c22cd1819cee16ea8d 148 SUPERFAMILY SSF55961 5 142 5.5E-24 T 10-11-2016 A4G23_RS26025 b73748e98aec66c22cd1819cee16ea8d 148 Gene3D G3DSA:3.30.530.20 7 141 2.1E-16 T 10-11-2016 IPR023393 START-like domain A4G23_RS26025 b73748e98aec66c22cd1819cee16ea8d 148 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 10 138 4.2E-9 T 10-11-2016 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 A4G23_RS25740 75b6f360f399dd17b00354787444e686 578 Pfam PF00474 Sodium:solute symporter family 34 198 1.9E-23 T 10-11-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 A4G23_RS25740 75b6f360f399dd17b00354787444e686 578 Pfam PF00474 Sodium:solute symporter family 311 499 4.2E-15 T 10-11-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 A4G23_RS03540 d839338bd6b2dcb3a9c6ba16d677c871 373 Pfam PF01180 Dihydroorotate dehydrogenase 50 348 8.3E-94 T 10-11-2016 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 A4G23_RS03540 d839338bd6b2dcb3a9c6ba16d677c871 373 SUPERFAMILY SSF51395 1 363 7.33E-101 T 10-11-2016 A4G23_RS03540 d839338bd6b2dcb3a9c6ba16d677c871 373 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 9 365 4.2E-125 T 10-11-2016 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 A4G23_RS03540 d839338bd6b2dcb3a9c6ba16d677c871 373 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 1 344 46.766 T 10-11-2016 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 A4G23_RS03540 d839338bd6b2dcb3a9c6ba16d677c871 373 Gene3D G3DSA:3.20.20.70 1 364 7.3E-127 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS03540 d839338bd6b2dcb3a9c6ba16d677c871 373 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 300 320 - T 10-11-2016 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 A4G23_RS08975 c6dd4b2b6cab5008d68e612b2dca2036 305 Gene3D G3DSA:3.20.20.70 10 296 5.4E-83 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS08975 c6dd4b2b6cab5008d68e612b2dca2036 305 Pfam PF00682 HMGL-like 11 282 6.0E-46 T 10-11-2016 IPR000891 Pyruvate carboxyltransferase GO:0003824 A4G23_RS08975 c6dd4b2b6cab5008d68e612b2dca2036 305 SUPERFAMILY SSF51569 8 302 5.68E-69 T 10-11-2016 A4G23_RS14800 81b101494a01e85d9ae2604cd476914f 755 SUPERFAMILY SSF56601 243 265 3.09E-91 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS14800 81b101494a01e85d9ae2604cd476914f 755 SUPERFAMILY SSF56601 299 678 3.09E-91 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS14800 81b101494a01e85d9ae2604cd476914f 755 Pfam PF00905 Penicillin binding protein transpeptidase domain 362 633 4.8E-31 T 10-11-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A4G23_RS14800 81b101494a01e85d9ae2604cd476914f 755 Gene3D G3DSA:3.40.710.10 264 687 1.1E-104 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS14800 81b101494a01e85d9ae2604cd476914f 755 Gene3D G3DSA:1.10.3810.10 77 263 6.7E-72 T 10-11-2016 A4G23_RS14800 81b101494a01e85d9ae2604cd476914f 755 Pfam PF00912 Transglycosylase 76 261 8.1E-63 T 10-11-2016 IPR001264 Glycosyl transferase, family 51 A4G23_RS14800 81b101494a01e85d9ae2604cd476914f 755 SUPERFAMILY SSF53955 64 287 5.62E-71 T 10-11-2016 IPR023346 Lysozyme-like domain A4G23_RS05990 7c17214e916bd4338353ea90831893f1 427 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 66 390 1.2E-50 T 10-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4G23_RS05990 7c17214e916bd4338353ea90831893f1 427 SUPERFAMILY SSF53686 15 402 1.44E-145 T 10-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4G23_RS05990 7c17214e916bd4338353ea90831893f1 427 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 19 401 3.0E-182 T 10-11-2016 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A4G23_RS05990 7c17214e916bd4338353ea90831893f1 427 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 93 107 - T 10-11-2016 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A4G23_RS05990 7c17214e916bd4338353ea90831893f1 427 PIRSF PIRSF001413 6 407 7.3E-157 T 10-11-2016 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A4G23_RS05990 7c17214e916bd4338353ea90831893f1 427 Gene3D G3DSA:3.40.50.1100 111 189 2.8E-22 T 10-11-2016 A4G23_RS05990 7c17214e916bd4338353ea90831893f1 427 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 14 403 51.598 T 10-11-2016 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A4G23_RS05990 7c17214e916bd4338353ea90831893f1 427 Gene3D G3DSA:3.40.50.1100 190 404 5.0E-98 T 10-11-2016 A4G23_RS13140 44e131b423fcb20bea62732ad8201b30 274 Gene3D G3DSA:1.20.120.450 6 60 4.8E-7 T 10-11-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase A4G23_RS13140 44e131b423fcb20bea62732ad8201b30 274 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 17 153 8.1E-20 T 10-11-2016 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 A4G23_RS13140 44e131b423fcb20bea62732ad8201b30 274 SUPERFAMILY SSF55718 184 268 5.18E-5 T 10-11-2016 IPR003033 SCP2 sterol-binding domain A4G23_RS13140 44e131b423fcb20bea62732ad8201b30 274 SUPERFAMILY SSF109854 3 159 2.2E-31 T 10-11-2016 A4G23_RS13140 44e131b423fcb20bea62732ad8201b30 274 Gene3D G3DSA:3.30.1050.10 185 265 1.5E-4 T 10-11-2016 IPR003033 SCP2 sterol-binding domain A4G23_RS13140 44e131b423fcb20bea62732ad8201b30 274 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 14 244 1.0E-39 T 10-11-2016 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type A4G23_RS08315 38f8c43dbc9da5220ab1a419d634c989 469 SUPERFAMILY SSF109998 245 428 8.11E-39 T 10-11-2016 IPR027304 Trigger factor/SurA domain A4G23_RS08315 38f8c43dbc9da5220ab1a419d634c989 469 Gene3D G3DSA:1.10.3120.10 211 394 1.8E-45 T 10-11-2016 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 A4G23_RS08315 38f8c43dbc9da5220ab1a419d634c989 469 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 157 215 4.2E-7 T 10-11-2016 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 A4G23_RS08315 38f8c43dbc9da5220ab1a419d634c989 469 TIGRFAM TIGR00115 tig: trigger factor 12 418 1.9E-121 T 10-11-2016 IPR005215 Trigger factor GO:0015031 A4G23_RS08315 38f8c43dbc9da5220ab1a419d634c989 469 Pfam PF05697 Bacterial trigger factor protein (TF) 3 145 3.8E-42 T 10-11-2016 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 A4G23_RS08315 38f8c43dbc9da5220ab1a419d634c989 469 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 258 420 7.2E-38 T 10-11-2016 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 A4G23_RS08315 38f8c43dbc9da5220ab1a419d634c989 469 PIRSF PIRSF003095 1 446 9.6E-125 T 10-11-2016 IPR005215 Trigger factor GO:0015031 A4G23_RS08315 38f8c43dbc9da5220ab1a419d634c989 469 Gene3D G3DSA:3.30.70.1050 3 119 5.5E-35 T 10-11-2016 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 A4G23_RS08315 38f8c43dbc9da5220ab1a419d634c989 469 Hamap MF_00303 Trigger factor [tig]. 1 425 19.553 T 10-11-2016 IPR005215 Trigger factor GO:0015031 A4G23_RS08315 38f8c43dbc9da5220ab1a419d634c989 469 Gene3D G3DSA:3.10.50.40 155 210 4.2E-5 T 10-11-2016 A4G23_RS08315 38f8c43dbc9da5220ab1a419d634c989 469 SUPERFAMILY SSF54534 133 244 2.55E-20 T 10-11-2016 A4G23_RS08315 38f8c43dbc9da5220ab1a419d634c989 469 SUPERFAMILY SSF102735 3 131 7.46E-37 T 10-11-2016 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 A4G23_RS06320 03dfbbf42ad6fd38e590b0034e7b20ce 695 Pfam PF12698 ABC-2 family transporter protein 490 675 7.8E-17 T 10-11-2016 A4G23_RS06320 03dfbbf42ad6fd38e590b0034e7b20ce 695 SUPERFAMILY SSF58104 342 453 2.35E-5 T 10-11-2016 A4G23_RS06320 03dfbbf42ad6fd38e590b0034e7b20ce 695 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 10 172 2.5E-59 T 10-11-2016 IPR017500 Phage infection protein, YhgE, N-terminal A4G23_RS06320 03dfbbf42ad6fd38e590b0034e7b20ce 695 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 477 682 1.1E-71 T 10-11-2016 IPR017501 Phage infection protein, YhgE, C-terminal A4G23_RS06320 03dfbbf42ad6fd38e590b0034e7b20ce 695 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 430 456 3.5E-4 T 10-11-2016 IPR023908 xxxLxxG heptad repeat A4G23_RS06320 03dfbbf42ad6fd38e590b0034e7b20ce 695 Gene3D G3DSA:1.10.287.950 333 437 2.1E-7 T 10-11-2016 A4G23_RS06320 03dfbbf42ad6fd38e590b0034e7b20ce 695 Pfam PF12051 Protein of unknown function (DUF3533) 28 140 6.4E-7 T 10-11-2016 IPR022703 Domain of unknown function DUF3533 A4G23_RS07135 d6fc7784bada1ca516217fd34902aeb9 489 ProSitePatterns PS00216 Sugar transport proteins signature 1. 83 99 - T 10-11-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A4G23_RS07135 d6fc7784bada1ca516217fd34902aeb9 489 SUPERFAMILY SSF103473 264 477 2.49E-64 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS07135 d6fc7784bada1ca516217fd34902aeb9 489 SUPERFAMILY SSF103473 19 214 2.49E-64 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS07135 d6fc7784bada1ca516217fd34902aeb9 489 PRINTS PR01036 Tetracycline resistance protein TetB signature 92 114 9.3E-7 T 10-11-2016 A4G23_RS07135 d6fc7784bada1ca516217fd34902aeb9 489 PRINTS PR01036 Tetracycline resistance protein TetB signature 32 56 9.3E-7 T 10-11-2016 A4G23_RS07135 d6fc7784bada1ca516217fd34902aeb9 489 PRINTS PR01036 Tetracycline resistance protein TetB signature 154 178 9.3E-7 T 10-11-2016 A4G23_RS07135 d6fc7784bada1ca516217fd34902aeb9 489 PRINTS PR01036 Tetracycline resistance protein TetB signature 219 237 9.3E-7 T 10-11-2016 A4G23_RS07135 d6fc7784bada1ca516217fd34902aeb9 489 Gene3D G3DSA:1.20.1250.20 27 213 3.1E-28 T 10-11-2016 A4G23_RS07135 d6fc7784bada1ca516217fd34902aeb9 489 Gene3D G3DSA:1.20.1250.20 275 476 7.1E-13 T 10-11-2016 A4G23_RS07135 d6fc7784bada1ca516217fd34902aeb9 489 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 30 434 1.6E-72 T 10-11-2016 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 A4G23_RS07135 d6fc7784bada1ca516217fd34902aeb9 489 Pfam PF07690 Major Facilitator Superfamily 34 426 1.2E-46 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS27230 cf54d5d293a6e308487a73878f32f889 1937 Pfam PF00550 Phosphopantetheine attachment site 1610 1672 1.1E-14 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS27230 cf54d5d293a6e308487a73878f32f889 1937 Pfam PF00550 Phosphopantetheine attachment site 541 603 5.0E-14 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS27230 cf54d5d293a6e308487a73878f32f889 1937 SUPERFAMILY SSF47336 1600 1672 2.75E-20 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS27230 cf54d5d293a6e308487a73878f32f889 1937 Pfam PF00668 Condensation domain 621 926 1.0E-59 T 10-11-2016 IPR001242 Condensation domain A4G23_RS27230 cf54d5d293a6e308487a73878f32f889 1937 SUPERFAMILY SSF53474 1675 1934 2.43E-55 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS27230 cf54d5d293a6e308487a73878f32f889 1937 SMART SM00823 Phosphopantetheine attachment site 539 608 1.8E-7 T 10-11-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4G23_RS27230 cf54d5d293a6e308487a73878f32f889 1937 SMART SM00823 Phosphopantetheine attachment site 1607 1676 8.7E-8 T 10-11-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4G23_RS27230 cf54d5d293a6e308487a73878f32f889 1937 SUPERFAMILY SSF47336 532 604 2.36E-18 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS27230 cf54d5d293a6e308487a73878f32f889 1937 Gene3D G3DSA:3.30.300.30 1494 1612 2.0E-40 T 10-11-2016 A4G23_RS27230 cf54d5d293a6e308487a73878f32f889 1937 Gene3D G3DSA:3.30.300.30 430 542 4.4E-35 T 10-11-2016 A4G23_RS27230 cf54d5d293a6e308487a73878f32f889 1937 SUPERFAMILY SSF52777 816 1086 7.11E-53 T 10-11-2016 A4G23_RS27230 cf54d5d293a6e308487a73878f32f889 1937 Gene3D G3DSA:1.10.1200.10 543 605 6.3E-24 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS27230 cf54d5d293a6e308487a73878f32f889 1937 Gene3D G3DSA:1.10.1200.10 1613 1674 2.1E-25 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS27230 cf54d5d293a6e308487a73878f32f889 1937 Gene3D G3DSA:3.40.50.1820 1868 1934 7.3E-47 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS27230 cf54d5d293a6e308487a73878f32f889 1937 Gene3D G3DSA:3.40.50.1820 1678 1798 7.3E-47 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS27230 cf54d5d293a6e308487a73878f32f889 1937 SUPERFAMILY SSF52777 624 803 1.45E-50 T 10-11-2016 A4G23_RS27230 cf54d5d293a6e308487a73878f32f889 1937 ProSitePatterns PS00455 Putative AMP-binding domain signature. 177 188 - T 10-11-2016 IPR020845 AMP-binding, conserved site A4G23_RS27230 cf54d5d293a6e308487a73878f32f889 1937 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1631 1646 - T 10-11-2016 IPR006162 Phosphopantetheine attachment site A4G23_RS27230 cf54d5d293a6e308487a73878f32f889 1937 SUPERFAMILY SSF56801 13 550 1.83E-145 T 10-11-2016 A4G23_RS27230 cf54d5d293a6e308487a73878f32f889 1937 ProSitePatterns PS00012 Phosphopantetheine attachment site. 563 578 - T 10-11-2016 IPR006162 Phosphopantetheine attachment site A4G23_RS27230 cf54d5d293a6e308487a73878f32f889 1937 Pfam PF00501 AMP-binding enzyme 1099 1499 1.2E-98 T 10-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A4G23_RS27230 cf54d5d293a6e308487a73878f32f889 1937 Pfam PF00501 AMP-binding enzyme 21 435 1.4E-85 T 10-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A4G23_RS27230 cf54d5d293a6e308487a73878f32f889 1937 Pfam PF13193 AMP-binding enzyme C-terminal domain 1507 1582 1.8E-13 T 10-11-2016 IPR025110 AMP-binding enzyme C-terminal domain A4G23_RS27230 cf54d5d293a6e308487a73878f32f889 1937 Pfam PF13193 AMP-binding enzyme C-terminal domain 444 514 1.6E-11 T 10-11-2016 IPR025110 AMP-binding enzyme C-terminal domain A4G23_RS27230 cf54d5d293a6e308487a73878f32f889 1937 Pfam PF00975 Thioesterase domain 1696 1919 5.4E-30 T 10-11-2016 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 A4G23_RS27230 cf54d5d293a6e308487a73878f32f889 1937 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1120 1523 1.5E-125 T 10-11-2016 IPR010071 Amino acid adenylation domain A4G23_RS27230 cf54d5d293a6e308487a73878f32f889 1937 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 77 459 5.1E-118 T 10-11-2016 IPR010071 Amino acid adenylation domain A4G23_RS27230 cf54d5d293a6e308487a73878f32f889 1937 Pfam PF13745 HxxPF-repeated domain 949 1045 5.7E-29 T 10-11-2016 A4G23_RS27230 cf54d5d293a6e308487a73878f32f889 1937 Gene3D G3DSA:3.40.50.980 1094 1249 1.2E-48 T 10-11-2016 A4G23_RS27230 cf54d5d293a6e308487a73878f32f889 1937 Gene3D G3DSA:3.40.50.980 14 185 3.0E-34 T 10-11-2016 A4G23_RS27230 cf54d5d293a6e308487a73878f32f889 1937 Gene3D G3DSA:2.30.38.10 1412 1489 2.1E-26 T 10-11-2016 A4G23_RS27230 cf54d5d293a6e308487a73878f32f889 1937 Gene3D G3DSA:2.30.38.10 349 424 4.1E-23 T 10-11-2016 A4G23_RS27230 cf54d5d293a6e308487a73878f32f889 1937 Gene3D G3DSA:3.40.50.980 186 337 9.6E-44 T 10-11-2016 A4G23_RS27230 cf54d5d293a6e308487a73878f32f889 1937 Gene3D G3DSA:3.40.50.980 1250 1411 1.1E-37 T 10-11-2016 A4G23_RS27230 cf54d5d293a6e308487a73878f32f889 1937 SUPERFAMILY SSF56801 1058 1620 1.1E-161 T 10-11-2016 A4G23_RS13455 4ee54749d53948ce66f8627da9ba7dfd 376 Gene3D G3DSA:3.40.50.300 248 350 8.0E-51 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS13455 4ee54749d53948ce66f8627da9ba7dfd 376 Gene3D G3DSA:3.40.50.300 1 167 8.0E-51 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS13455 4ee54749d53948ce66f8627da9ba7dfd 376 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 376 97.348 T 10-11-2016 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 A4G23_RS13455 4ee54749d53948ce66f8627da9ba7dfd 376 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 1 365 1.5E-127 T 10-11-2016 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 A4G23_RS13455 4ee54749d53948ce66f8627da9ba7dfd 376 ProSitePatterns PS00617 RecF protein signature 1. 117 137 - T 10-11-2016 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 A4G23_RS13455 4ee54749d53948ce66f8627da9ba7dfd 376 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 351 2.1E-17 T 10-11-2016 IPR003395 RecF/RecN/SMC, N-terminal A4G23_RS13455 4ee54749d53948ce66f8627da9ba7dfd 376 SUPERFAMILY SSF52540 252 350 1.19E-39 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS13455 4ee54749d53948ce66f8627da9ba7dfd 376 SUPERFAMILY SSF52540 1 223 1.19E-39 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS13455 4ee54749d53948ce66f8627da9ba7dfd 376 ProSitePatterns PS00618 RecF protein signature 2. 319 337 - T 10-11-2016 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 A4G23_RS06875 4e136a5328b8f04d938e83aeca570344 356 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 47 4.6E-14 T 10-11-2016 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4G23_RS06875 4e136a5328b8f04d938e83aeca570344 356 SUPERFAMILY SSF53822 59 337 1.32E-67 T 10-11-2016 IPR028082 Periplasmic binding protein-like I A4G23_RS06875 4e136a5328b8f04d938e83aeca570344 356 Gene3D G3DSA:1.10.260.40 3 47 5.1E-18 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS06875 4e136a5328b8f04d938e83aeca570344 356 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 7.6E-5 T 10-11-2016 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4G23_RS06875 4e136a5328b8f04d938e83aeca570344 356 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 7.6E-5 T 10-11-2016 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4G23_RS06875 4e136a5328b8f04d938e83aeca570344 356 Pfam PF13377 Periplasmic binding protein-like domain 171 333 4.9E-38 T 10-11-2016 A4G23_RS06875 4e136a5328b8f04d938e83aeca570344 356 SUPERFAMILY SSF47413 3 49 8.09E-12 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS06875 4e136a5328b8f04d938e83aeca570344 356 Gene3D G3DSA:3.40.50.2300 171 334 6.0E-54 T 10-11-2016 A4G23_RS06875 4e136a5328b8f04d938e83aeca570344 356 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 10-11-2016 A4G23_RS06875 4e136a5328b8f04d938e83aeca570344 356 SMART SM00354 2 69 9.5E-24 T 10-11-2016 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4G23_RS06875 4e136a5328b8f04d938e83aeca570344 356 Gene3D G3DSA:3.40.50.2300 58 170 1.3E-26 T 10-11-2016 A4G23_RS17390 0318c909508590c583d8dad8e817de51 532 Gene3D G3DSA:3.30.379.10 56 168 6.2E-14 T 10-11-2016 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A4G23_RS17390 0318c909508590c583d8dad8e817de51 532 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 61 178 2.1E-12 T 10-11-2016 IPR015882 Beta-hexosaminidase, bacteial type, N-terminal KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 A4G23_RS17390 0318c909508590c583d8dad8e817de51 532 SUPERFAMILY SSF51445 183 524 1.14E-73 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS17390 0318c909508590c583d8dad8e817de51 532 Gene3D G3DSA:3.20.20.80 169 526 2.7E-72 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS17390 0318c909508590c583d8dad8e817de51 532 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 185 509 1.6E-39 T 10-11-2016 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 A4G23_RS17390 0318c909508590c583d8dad8e817de51 532 PRINTS PR00738 Glycosyl hydrolase family 20 signature 473 489 9.9E-21 T 10-11-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A4G23_RS17390 0318c909508590c583d8dad8e817de51 532 PRINTS PR00738 Glycosyl hydrolase family 20 signature 253 270 9.9E-21 T 10-11-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A4G23_RS17390 0318c909508590c583d8dad8e817de51 532 PRINTS PR00738 Glycosyl hydrolase family 20 signature 176 193 9.9E-21 T 10-11-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A4G23_RS17390 0318c909508590c583d8dad8e817de51 532 PRINTS PR00738 Glycosyl hydrolase family 20 signature 317 330 9.9E-21 T 10-11-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A4G23_RS17390 0318c909508590c583d8dad8e817de51 532 PRINTS PR00738 Glycosyl hydrolase family 20 signature 144 164 9.9E-21 T 10-11-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A4G23_RS17390 0318c909508590c583d8dad8e817de51 532 PRINTS PR00738 Glycosyl hydrolase family 20 signature 295 313 9.9E-21 T 10-11-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A4G23_RS17390 0318c909508590c583d8dad8e817de51 532 SUPERFAMILY SSF55545 61 181 1.31E-12 T 10-11-2016 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A4G23_RS22755 6b1e38ec338324c7eb7b6461acf0d25d 410 Pfam PF02274 Amidinotransferase 17 407 5.4E-89 T 10-11-2016 A4G23_RS22755 6b1e38ec338324c7eb7b6461acf0d25d 410 Gene3D G3DSA:3.75.10.10 151 409 1.3E-126 T 10-11-2016 A4G23_RS22755 6b1e38ec338324c7eb7b6461acf0d25d 410 Gene3D G3DSA:3.75.10.10 2 66 1.3E-126 T 10-11-2016 A4G23_RS22755 6b1e38ec338324c7eb7b6461acf0d25d 410 Hamap MF_00242 Arginine deiminase [arcA]. 1 410 42.101 T 10-11-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 A4G23_RS22755 6b1e38ec338324c7eb7b6461acf0d25d 410 SUPERFAMILY SSF55909 2 409 1.04E-125 T 10-11-2016 A4G23_RS22755 6b1e38ec338324c7eb7b6461acf0d25d 410 PRINTS PR01466 Bacterial arginine deiminase signature 179 194 2.0E-48 T 10-11-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 A4G23_RS22755 6b1e38ec338324c7eb7b6461acf0d25d 410 PRINTS PR01466 Bacterial arginine deiminase signature 1 20 2.0E-48 T 10-11-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 A4G23_RS22755 6b1e38ec338324c7eb7b6461acf0d25d 410 PRINTS PR01466 Bacterial arginine deiminase signature 366 380 2.0E-48 T 10-11-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 A4G23_RS22755 6b1e38ec338324c7eb7b6461acf0d25d 410 PRINTS PR01466 Bacterial arginine deiminase signature 151 169 2.0E-48 T 10-11-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 A4G23_RS22755 6b1e38ec338324c7eb7b6461acf0d25d 410 PRINTS PR01466 Bacterial arginine deiminase signature 346 363 2.0E-48 T 10-11-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 A4G23_RS22755 6b1e38ec338324c7eb7b6461acf0d25d 410 PRINTS PR01466 Bacterial arginine deiminase signature 389 407 2.0E-48 T 10-11-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 A4G23_RS22755 6b1e38ec338324c7eb7b6461acf0d25d 410 PIRSF PIRSF006356 1 410 3.6E-147 T 10-11-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 A4G23_RS09020 dac06f153154976bbd35ea8986b901c2 605 Gene3D G3DSA:3.40.50.10490 443 605 1.0E-57 T 10-11-2016 A4G23_RS09020 dac06f153154976bbd35ea8986b901c2 605 SUPERFAMILY SSF53697 245 605 1.39E-100 T 10-11-2016 A4G23_RS09020 dac06f153154976bbd35ea8986b901c2 605 Gene3D G3DSA:3.60.20.10 2 239 6.9E-73 T 10-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal A4G23_RS09020 dac06f153154976bbd35ea8986b901c2 605 SUPERFAMILY SSF56235 2 232 2.66E-65 T 10-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal A4G23_RS09020 dac06f153154976bbd35ea8986b901c2 605 Pfam PF13522 Glutamine amidotransferase domain 64 193 6.0E-20 T 10-11-2016 A4G23_RS09020 dac06f153154976bbd35ea8986b901c2 605 Gene3D G3DSA:3.40.50.10490 245 442 1.3E-69 T 10-11-2016 A4G23_RS09020 dac06f153154976bbd35ea8986b901c2 605 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 605 3.6E-225 T 10-11-2016 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 A4G23_RS09020 dac06f153154976bbd35ea8986b901c2 605 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 605 37.613 T 10-11-2016 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 A4G23_RS09020 dac06f153154976bbd35ea8986b901c2 605 Pfam PF01380 SIS domain 295 417 5.0E-28 T 10-11-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 A4G23_RS09020 dac06f153154976bbd35ea8986b901c2 605 Pfam PF01380 SIS domain 462 587 8.5E-20 T 10-11-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 A4G23_RS13070 6cc2377e08f2b123d0690e92ee33e869 588 Hamap MF_00044 Aspartate--tRNA(Asp) ligase [aspS]. 4 561 33.216 T 10-11-2016 A4G23_RS13070 6cc2377e08f2b123d0690e92ee33e869 588 SUPERFAMILY SSF55681 117 298 4.02E-93 T 10-11-2016 A4G23_RS13070 6cc2377e08f2b123d0690e92ee33e869 588 SUPERFAMILY SSF55681 422 582 4.02E-93 T 10-11-2016 A4G23_RS13070 6cc2377e08f2b123d0690e92ee33e869 588 Gene3D G3DSA:3.30.930.10 411 582 7.9E-97 T 10-11-2016 A4G23_RS13070 6cc2377e08f2b123d0690e92ee33e869 588 Gene3D G3DSA:3.30.930.10 136 282 7.9E-97 T 10-11-2016 A4G23_RS13070 6cc2377e08f2b123d0690e92ee33e869 588 PRINTS PR01042 Aspartyl-tRNA synthetase signature 516 530 1.2E-21 T 10-11-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4G23_RS13070 6cc2377e08f2b123d0690e92ee33e869 588 PRINTS PR01042 Aspartyl-tRNA synthetase signature 194 206 1.2E-21 T 10-11-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4G23_RS13070 6cc2377e08f2b123d0690e92ee33e869 588 PRINTS PR01042 Aspartyl-tRNA synthetase signature 472 488 1.2E-21 T 10-11-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4G23_RS13070 6cc2377e08f2b123d0690e92ee33e869 588 PRINTS PR01042 Aspartyl-tRNA synthetase signature 211 224 1.2E-21 T 10-11-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4G23_RS13070 6cc2377e08f2b123d0690e92ee33e869 588 SUPERFAMILY SSF55261 297 413 7.68E-34 T 10-11-2016 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 A4G23_RS13070 6cc2377e08f2b123d0690e92ee33e869 588 Gene3D G3DSA:2.40.50.140 4 107 2.8E-34 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS13070 6cc2377e08f2b123d0690e92ee33e869 588 Pfam PF00152 tRNA synthetases class II (D, K and N) 122 555 4.5E-94 T 10-11-2016 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4G23_RS13070 6cc2377e08f2b123d0690e92ee33e869 588 SUPERFAMILY SSF50249 4 107 1.14E-28 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS13070 6cc2377e08f2b123d0690e92ee33e869 588 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 5 582 5.5E-185 T 10-11-2016 IPR004524 Aspartate-tRNA ligase, bacterial/mitochondrial-type GO:0005524|GO:0016874 Reactome: R-HSA-379726 A4G23_RS13070 6cc2377e08f2b123d0690e92ee33e869 588 Pfam PF02938 GAD domain 315 403 1.9E-21 T 10-11-2016 IPR029351 GAD domain Reactome: R-HSA-379726 A4G23_RS13070 6cc2377e08f2b123d0690e92ee33e869 588 Gene3D G3DSA:3.30.1360.30 283 410 1.9E-42 T 10-11-2016 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 A4G23_RS13070 6cc2377e08f2b123d0690e92ee33e869 588 Pfam PF01336 OB-fold nucleic acid binding domain 21 104 6.4E-14 T 10-11-2016 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A4G23_RS03010 af7b15474b43ca0a9f6002b30efb1f29 216 Gene3D G3DSA:1.10.1780.10 134 205 2.0E-12 T 10-11-2016 IPR004176 Clp, N-terminal GO:0019538 A4G23_RS03010 af7b15474b43ca0a9f6002b30efb1f29 216 Gene3D G3DSA:1.10.1780.10 14 71 2.0E-12 T 10-11-2016 IPR004176 Clp, N-terminal GO:0019538 A4G23_RS03010 af7b15474b43ca0a9f6002b30efb1f29 216 SUPERFAMILY SSF81923 145 207 2.55E-5 T 10-11-2016 IPR004176 Clp, N-terminal GO:0019538 A4G23_RS03010 af7b15474b43ca0a9f6002b30efb1f29 216 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 21 44 0.028 T 10-11-2016 IPR004176 Clp, N-terminal GO:0019538 A4G23_RS03010 af7b15474b43ca0a9f6002b30efb1f29 216 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 173 204 0.11 T 10-11-2016 IPR004176 Clp, N-terminal GO:0019538 A4G23_RS21540 2d4aadebcfaf792138770561579784d8 859 Pfam PF00512 His Kinase A (phospho-acceptor) domain 628 695 2.3E-17 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS21540 2d4aadebcfaf792138770561579784d8 859 PRINTS PR00344 Bacterial sensor protein C-terminal signature 829 842 5.2E-11 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS21540 2d4aadebcfaf792138770561579784d8 859 PRINTS PR00344 Bacterial sensor protein C-terminal signature 790 800 5.2E-11 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS21540 2d4aadebcfaf792138770561579784d8 859 PRINTS PR00344 Bacterial sensor protein C-terminal signature 772 786 5.2E-11 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS21540 2d4aadebcfaf792138770561579784d8 859 PRINTS PR00344 Bacterial sensor protein C-terminal signature 805 823 5.2E-11 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS21540 2d4aadebcfaf792138770561579784d8 859 Gene3D G3DSA:3.40.50.300 2 210 6.0E-96 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS21540 2d4aadebcfaf792138770561579784d8 859 Gene3D G3DSA:1.20.120.620 408 491 7.4E-16 T 10-11-2016 A4G23_RS21540 2d4aadebcfaf792138770561579784d8 859 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 3 211 6.3E-97 T 10-11-2016 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 A4G23_RS21540 2d4aadebcfaf792138770561579784d8 859 Gene3D G3DSA:3.30.565.10 681 847 1.6E-37 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS21540 2d4aadebcfaf792138770561579784d8 859 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 736 844 2.8E-19 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS21540 2d4aadebcfaf792138770561579784d8 859 Pfam PF13493 Domain of unknown function (DUF4118) 385 500 4.9E-23 T 10-11-2016 IPR025201 Sensor protein KdpD, transmembrane domain A4G23_RS21540 2d4aadebcfaf792138770561579784d8 859 SUPERFAMILY SSF52402 232 347 1.45E-10 T 10-11-2016 A4G23_RS21540 2d4aadebcfaf792138770561579784d8 859 Gene3D G3DSA:1.10.287.130 618 680 1.6E-18 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS21540 2d4aadebcfaf792138770561579784d8 859 SMART SM00388 627 695 3.0E-19 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS21540 2d4aadebcfaf792138770561579784d8 859 SUPERFAMILY SSF47384 618 695 4.32E-17 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS21540 2d4aadebcfaf792138770561579784d8 859 Gene3D G3DSA:3.40.50.620 228 346 2.4E-11 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS21540 2d4aadebcfaf792138770561579784d8 859 SMART SM00387 735 845 2.9E-31 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS21540 2d4aadebcfaf792138770561579784d8 859 Pfam PF00582 Universal stress protein family 232 344 3.0E-7 T 10-11-2016 IPR006016 UspA GO:0006950 A4G23_RS21540 2d4aadebcfaf792138770561579784d8 859 SUPERFAMILY SSF55874 685 848 7.99E-37 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS17570 15d168e90b3ca717a55ac68fd85021d0 112 SUPERFAMILY SSF47413 43 108 9.57E-15 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS17570 15d168e90b3ca717a55ac68fd85021d0 112 Pfam PF13744 Helix-turn-helix domain 30 101 1.4E-12 T 10-11-2016 A4G23_RS17570 15d168e90b3ca717a55ac68fd85021d0 112 Gene3D G3DSA:1.10.260.40 43 103 6.1E-13 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS17570 15d168e90b3ca717a55ac68fd85021d0 112 SMART SM00530 45 101 1.0E-8 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS17065 a3a4396263e8398dabe0035e5ae7c275 532 SUPERFAMILY SSF52317 18 209 1.31E-53 T 10-11-2016 IPR029062 Class I glutamine amidotransferase-like A4G23_RS17065 a3a4396263e8398dabe0035e5ae7c275 532 Gene3D G3DSA:3.30.300.10 407 532 4.1E-49 T 10-11-2016 A4G23_RS17065 a3a4396263e8398dabe0035e5ae7c275 532 Pfam PF00117 Glutamine amidotransferase class-I 20 200 2.1E-40 T 10-11-2016 IPR017926 Glutamine amidotransferase A4G23_RS17065 a3a4396263e8398dabe0035e5ae7c275 532 SUPERFAMILY SSF52402 194 452 9.48E-59 T 10-11-2016 A4G23_RS17065 a3a4396263e8398dabe0035e5ae7c275 532 Pfam PF00958 GMP synthase C terminal domain 439 531 7.1E-39 T 10-11-2016 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 A4G23_RS17065 a3a4396263e8398dabe0035e5ae7c275 532 Gene3D G3DSA:3.40.50.620 224 406 9.3E-58 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS17065 a3a4396263e8398dabe0035e5ae7c275 532 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 213 532 3.5E-149 T 10-11-2016 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 A4G23_RS17065 a3a4396263e8398dabe0035e5ae7c275 532 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 18 200 6.9E-73 T 10-11-2016 IPR004739 GMP synthase, N-terminal GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 A4G23_RS17065 a3a4396263e8398dabe0035e5ae7c275 532 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 89 105 6.5E-6 T 10-11-2016 A4G23_RS17065 a3a4396263e8398dabe0035e5ae7c275 532 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 18 32 6.5E-6 T 10-11-2016 A4G23_RS17065 a3a4396263e8398dabe0035e5ae7c275 532 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 59 73 6.5E-6 T 10-11-2016 A4G23_RS17065 a3a4396263e8398dabe0035e5ae7c275 532 PRINTS PR00097 Anthranilate synthase component II signature 89 100 5.5E-6 T 10-11-2016 A4G23_RS17065 a3a4396263e8398dabe0035e5ae7c275 532 PRINTS PR00097 Anthranilate synthase component II signature 62 71 5.5E-6 T 10-11-2016 A4G23_RS17065 a3a4396263e8398dabe0035e5ae7c275 532 PRINTS PR00097 Anthranilate synthase component II signature 178 191 5.5E-6 T 10-11-2016 A4G23_RS17065 a3a4396263e8398dabe0035e5ae7c275 532 Pfam PF02540 NAD synthase 224 293 1.2E-6 T 10-11-2016 IPR022310 NAD/GMP synthase A4G23_RS17065 a3a4396263e8398dabe0035e5ae7c275 532 Gene3D G3DSA:3.40.50.880 11 223 1.1E-58 T 10-11-2016 IPR029062 Class I glutamine amidotransferase-like A4G23_RS17065 a3a4396263e8398dabe0035e5ae7c275 532 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 15 532 54.069 T 10-11-2016 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 A4G23_RS17065 a3a4396263e8398dabe0035e5ae7c275 532 SUPERFAMILY SSF54810 411 532 3.4E-47 T 10-11-2016 A4G23_RS17065 a3a4396263e8398dabe0035e5ae7c275 532 PRINTS PR00096 Glutamine amidotransferase superfamily signature 178 191 7.6E-8 T 10-11-2016 A4G23_RS17065 a3a4396263e8398dabe0035e5ae7c275 532 PRINTS PR00096 Glutamine amidotransferase superfamily signature 89 100 7.6E-8 T 10-11-2016 A4G23_RS17065 a3a4396263e8398dabe0035e5ae7c275 532 PRINTS PR00096 Glutamine amidotransferase superfamily signature 62 71 7.6E-8 T 10-11-2016 A4G23_RS18440 c11f3a435eb06b8d1d7d2c38cd67a09d 307 Gene3D G3DSA:1.10.3720.10 89 301 5.1E-19 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS18440 c11f3a435eb06b8d1d7d2c38cd67a09d 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 306 2.2E-37 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS18440 c11f3a435eb06b8d1d7d2c38cd67a09d 307 SUPERFAMILY SSF161098 90 288 5.23E-21 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS19545 16dd305a6cdc2b92c5b33f6bc8756af9 276 ProSitePatterns PS00449 ATP synthase a subunit signature. 199 208 - T 10-11-2016 IPR023011 ATPase, F0 complex, subunit A, active site Reactome: R-HSA-163210 A4G23_RS19545 16dd305a6cdc2b92c5b33f6bc8756af9 276 Hamap MF_01393 ATP synthase subunit a [atpB]. 1 275 13.457 T 10-11-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 A4G23_RS19545 16dd305a6cdc2b92c5b33f6bc8756af9 276 SUPERFAMILY SSF81336 102 269 1.96E-36 T 10-11-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 A4G23_RS19545 16dd305a6cdc2b92c5b33f6bc8756af9 276 Gene3D G3DSA:1.20.120.220 102 274 6.2E-40 T 10-11-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 A4G23_RS19545 16dd305a6cdc2b92c5b33f6bc8756af9 276 Pfam PF00119 ATP synthase A chain 54 269 3.7E-48 T 10-11-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 A4G23_RS19545 16dd305a6cdc2b92c5b33f6bc8756af9 276 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 49 271 1.2E-44 T 10-11-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 A4G23_RS19545 16dd305a6cdc2b92c5b33f6bc8756af9 276 PRINTS PR00123 ATP synthase A subunit signature 255 270 1.9E-19 T 10-11-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 A4G23_RS19545 16dd305a6cdc2b92c5b33f6bc8756af9 276 PRINTS PR00123 ATP synthase A subunit signature 196 218 1.9E-19 T 10-11-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 A4G23_RS19545 16dd305a6cdc2b92c5b33f6bc8756af9 276 PRINTS PR00123 ATP synthase A subunit signature 111 127 1.9E-19 T 10-11-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 A4G23_RS14500 cb5b25cdd0744b87a548026589de5974 273 Pfam PF01263 Aldose 1-epimerase 20 230 5.2E-17 T 10-11-2016 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 A4G23_RS14500 cb5b25cdd0744b87a548026589de5974 273 SUPERFAMILY SSF74650 6 247 8.16E-37 T 10-11-2016 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 A4G23_RS14500 cb5b25cdd0744b87a548026589de5974 273 Gene3D G3DSA:2.70.98.10 5 147 9.3E-13 T 10-11-2016 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0003824|GO:0005975|GO:0030246 A4G23_RS22065 563e1bba5f73ad8f8d9c2e58d91235ab 3156 Gene3D G3DSA:3.40.50.170 7 175 2.1E-25 T 10-11-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A4G23_RS22065 563e1bba5f73ad8f8d9c2e58d91235ab 3156 Gene3D G3DSA:3.40.50.980 726 865 9.3E-36 T 10-11-2016 A4G23_RS22065 563e1bba5f73ad8f8d9c2e58d91235ab 3156 SUPERFAMILY SSF47336 1110 1187 2.62E-11 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS22065 563e1bba5f73ad8f8d9c2e58d91235ab 3156 SUPERFAMILY SSF47336 1233 1263 2.62E-11 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS22065 563e1bba5f73ad8f8d9c2e58d91235ab 3156 Gene3D G3DSA:3.40.50.980 563 725 4.1E-36 T 10-11-2016 A4G23_RS22065 563e1bba5f73ad8f8d9c2e58d91235ab 3156 SUPERFAMILY SSF53901 1247 1612 1.59E-81 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS22065 563e1bba5f73ad8f8d9c2e58d91235ab 3156 SUPERFAMILY SSF53901 1642 1664 1.59E-81 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS22065 563e1bba5f73ad8f8d9c2e58d91235ab 3156 Gene3D G3DSA:2.30.38.10 866 939 2.0E-23 T 10-11-2016 A4G23_RS22065 563e1bba5f73ad8f8d9c2e58d91235ab 3156 Pfam PF00550 Phosphopantetheine attachment site 2118 2181 1.3E-10 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS22065 563e1bba5f73ad8f8d9c2e58d91235ab 3156 Pfam PF00550 Phosphopantetheine attachment site 1119 1182 7.1E-8 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS22065 563e1bba5f73ad8f8d9c2e58d91235ab 3156 Gene3D G3DSA:3.30.70.250 2909 2960 2.7E-6 T 10-11-2016 A4G23_RS22065 563e1bba5f73ad8f8d9c2e58d91235ab 3156 Pfam PF14765 Polyketide synthase dehydratase 1839 2059 3.1E-19 T 10-11-2016 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4G23_RS22065 563e1bba5f73ad8f8d9c2e58d91235ab 3156 Gene3D G3DSA:3.30.300.30 945 1045 2.7E-25 T 10-11-2016 A4G23_RS22065 563e1bba5f73ad8f8d9c2e58d91235ab 3156 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 590 975 5.5E-113 T 10-11-2016 IPR010071 Amino acid adenylation domain A4G23_RS22065 563e1bba5f73ad8f8d9c2e58d91235ab 3156 Gene3D G3DSA:1.10.1200.10 2113 2185 3.7E-13 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS22065 563e1bba5f73ad8f8d9c2e58d91235ab 3156 SUPERFAMILY SSF53328 6 175 5.63E-31 T 10-11-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A4G23_RS22065 563e1bba5f73ad8f8d9c2e58d91235ab 3156 SUPERFAMILY SSF53901 2265 2631 2.94E-80 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS22065 563e1bba5f73ad8f8d9c2e58d91235ab 3156 SUPERFAMILY SSF53901 2664 2685 2.94E-80 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS22065 563e1bba5f73ad8f8d9c2e58d91235ab 3156 Gene3D G3DSA:3.40.47.10 1504 1667 9.1E-57 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS22065 563e1bba5f73ad8f8d9c2e58d91235ab 3156 Gene3D G3DSA:3.40.47.10 2523 2689 1.4E-55 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS22065 563e1bba5f73ad8f8d9c2e58d91235ab 3156 Pfam PF00551 Formyl transferase 73 161 1.1E-9 T 10-11-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A4G23_RS22065 563e1bba5f73ad8f8d9c2e58d91235ab 3156 SUPERFAMILY SSF55048 2910 2960 7.19E-8 T 10-11-2016 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 A4G23_RS22065 563e1bba5f73ad8f8d9c2e58d91235ab 3156 SMART SM01294 2116 2182 3.7E-5 T 10-11-2016 A4G23_RS22065 563e1bba5f73ad8f8d9c2e58d91235ab 3156 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1499 1616 5.0E-39 T 10-11-2016 IPR014031 Beta-ketoacyl synthase, C-terminal A4G23_RS22065 563e1bba5f73ad8f8d9c2e58d91235ab 3156 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2519 2635 8.0E-39 T 10-11-2016 IPR014031 Beta-ketoacyl synthase, C-terminal A4G23_RS22065 563e1bba5f73ad8f8d9c2e58d91235ab 3156 SUPERFAMILY SSF52151 2785 2912 1.02E-63 T 10-11-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 A4G23_RS22065 563e1bba5f73ad8f8d9c2e58d91235ab 3156 SUPERFAMILY SSF52151 2972 3075 1.02E-63 T 10-11-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 A4G23_RS22065 563e1bba5f73ad8f8d9c2e58d91235ab 3156 Pfam PF00698 Acyl transferase domain 2787 3065 1.6E-54 T 10-11-2016 IPR014043 Acyl transferase A4G23_RS22065 563e1bba5f73ad8f8d9c2e58d91235ab 3156 Gene3D G3DSA:3.40.47.10 1252 1503 4.4E-83 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS22065 563e1bba5f73ad8f8d9c2e58d91235ab 3156 Gene3D G3DSA:3.40.47.10 2269 2522 6.8E-81 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS22065 563e1bba5f73ad8f8d9c2e58d91235ab 3156 Pfam PF13193 AMP-binding enzyme C-terminal domain 959 1033 1.7E-6 T 10-11-2016 IPR025110 AMP-binding enzyme C-terminal domain A4G23_RS22065 563e1bba5f73ad8f8d9c2e58d91235ab 3156 Pfam PF00501 AMP-binding enzyme 568 951 4.8E-77 T 10-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A4G23_RS22065 563e1bba5f73ad8f8d9c2e58d91235ab 3156 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2268 2509 3.4E-71 T 10-11-2016 IPR014030 Beta-ketoacyl synthase, N-terminal A4G23_RS22065 563e1bba5f73ad8f8d9c2e58d91235ab 3156 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1252 1491 7.4E-70 T 10-11-2016 IPR014030 Beta-ketoacyl synthase, N-terminal A4G23_RS22065 563e1bba5f73ad8f8d9c2e58d91235ab 3156 Gene3D G3DSA:1.10.1200.10 1111 1184 7.9E-13 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS22065 563e1bba5f73ad8f8d9c2e58d91235ab 3156 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1619 1701 2.7E-13 T 10-11-2016 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4G23_RS22065 563e1bba5f73ad8f8d9c2e58d91235ab 3156 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2638 2747 6.8E-13 T 10-11-2016 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4G23_RS22065 563e1bba5f73ad8f8d9c2e58d91235ab 3156 SMART SM00823 Phosphopantetheine attachment site 2115 2186 3.4E-13 T 10-11-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4G23_RS22065 563e1bba5f73ad8f8d9c2e58d91235ab 3156 SMART SM00823 Phosphopantetheine attachment site 1117 1186 0.0018 T 10-11-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4G23_RS22065 563e1bba5f73ad8f8d9c2e58d91235ab 3156 Gene3D G3DSA:3.40.366.10 2784 2906 5.3E-69 T 10-11-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 A4G23_RS22065 563e1bba5f73ad8f8d9c2e58d91235ab 3156 Gene3D G3DSA:3.40.366.10 2970 3079 5.3E-69 T 10-11-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 A4G23_RS22065 563e1bba5f73ad8f8d9c2e58d91235ab 3156 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1404 1420 - T 10-11-2016 IPR018201 Beta-ketoacyl synthase, active site A4G23_RS22065 563e1bba5f73ad8f8d9c2e58d91235ab 3156 SUPERFAMILY SSF56801 563 1045 6.02E-125 T 10-11-2016 A4G23_RS22065 563e1bba5f73ad8f8d9c2e58d91235ab 3156 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2788 3079 3.2E-91 T 10-11-2016 IPR020801 Polyketide synthase, acyl transferase domain A4G23_RS22065 563e1bba5f73ad8f8d9c2e58d91235ab 3156 SMART SM00825 Beta-ketoacyl synthase 2269 2689 1.9E-176 T 10-11-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4G23_RS22065 563e1bba5f73ad8f8d9c2e58d91235ab 3156 SMART SM00825 Beta-ketoacyl synthase 1251 1667 1.9E-169 T 10-11-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4G23_RS22065 563e1bba5f73ad8f8d9c2e58d91235ab 3156 SUPERFAMILY SSF47336 2112 2187 2.62E-15 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS10815 22e1d5203fdecacb317af112599ee8ab 2013 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1462 1502 0.0018 T 10-11-2016 IPR006530 YD repeat A4G23_RS10815 22e1d5203fdecacb317af112599ee8ab 2013 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1795 1870 1.7E-13 T 10-11-2016 IPR022385 Rhs repeat-associated core GO:0097264 A4G23_RS10815 22e1d5203fdecacb317af112599ee8ab 2013 ProDom PD039135 WALL-ASSOCIATED REPEAT PROTEIN CELL WALL HYDROLASE PRECURSOR SIGNAL TRANSMEMBRANE RETICULOCYTE 12 198 1.0E-4 T 10-11-2016 A4G23_RS15000 6f97449f34bf862e912c13a2a4e7b3e7 253 Gene3D G3DSA:3.40.50.1820 2 248 2.1E-53 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS15000 6f97449f34bf862e912c13a2a4e7b3e7 253 Pfam PF12697 Alpha/beta hydrolase family 14 239 3.5E-18 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS15000 6f97449f34bf862e912c13a2a4e7b3e7 253 PRINTS PR00111 Alpha/beta hydrolase fold signature 93 106 8.2E-7 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS15000 6f97449f34bf862e912c13a2a4e7b3e7 253 PRINTS PR00111 Alpha/beta hydrolase fold signature 38 53 8.2E-7 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS15000 6f97449f34bf862e912c13a2a4e7b3e7 253 PRINTS PR00111 Alpha/beta hydrolase fold signature 79 92 8.2E-7 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS15000 6f97449f34bf862e912c13a2a4e7b3e7 253 SUPERFAMILY SSF53474 2 247 1.36E-52 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS21260 1fb1f85d5cd47f8ae134da4cd63cbd9d 730 SUPERFAMILY SSF81271 465 521 3.05E-10 T 10-11-2016 IPR012676 TGS-like KEGG: 00970+6.1.1.3 A4G23_RS21260 1fb1f85d5cd47f8ae134da4cd63cbd9d 730 SMART SM00471 80 190 1.2E-11 T 10-11-2016 IPR003607 HD/PDEase domain A4G23_RS21260 1fb1f85d5cd47f8ae134da4cd63cbd9d 730 Gene3D G3DSA:3.30.460.10 241 359 2.9E-22 T 10-11-2016 A4G23_RS21260 1fb1f85d5cd47f8ae134da4cd63cbd9d 730 Pfam PF13328 HD domain 65 212 3.8E-41 T 10-11-2016 IPR003607 HD/PDEase domain A4G23_RS21260 1fb1f85d5cd47f8ae134da4cd63cbd9d 730 Pfam PF13291 ACT domain 649 721 2.9E-10 T 10-11-2016 IPR002912 ACT domain GO:0008152|GO:0016597 A4G23_RS21260 1fb1f85d5cd47f8ae134da4cd63cbd9d 730 SUPERFAMILY SSF55021 645 724 9.16E-5 T 10-11-2016 A4G23_RS21260 1fb1f85d5cd47f8ae134da4cd63cbd9d 730 Gene3D G3DSA:3.30.70.260 658 719 1.8E-4 T 10-11-2016 A4G23_RS21260 1fb1f85d5cd47f8ae134da4cd63cbd9d 730 SUPERFAMILY SSF109604 47 228 8.16E-63 T 10-11-2016 A4G23_RS21260 1fb1f85d5cd47f8ae134da4cd63cbd9d 730 Pfam PF02824 TGS domain 465 521 1.7E-14 T 10-11-2016 IPR004095 TGS KEGG: 00970+6.1.1.3 A4G23_RS21260 1fb1f85d5cd47f8ae134da4cd63cbd9d 730 Gene3D G3DSA:3.10.20.30 464 521 1.1E-12 T 10-11-2016 IPR012675 Beta-grasp domain A4G23_RS21260 1fb1f85d5cd47f8ae134da4cd63cbd9d 730 SMART SM00954 271 379 7.6E-25 T 10-11-2016 IPR007685 RelA/SpoT GO:0015969 A4G23_RS21260 1fb1f85d5cd47f8ae134da4cd63cbd9d 730 Pfam PF04607 Region found in RelA / SpoT proteins 299 366 1.6E-13 T 10-11-2016 IPR007685 RelA/SpoT GO:0015969 A4G23_RS21260 1fb1f85d5cd47f8ae134da4cd63cbd9d 730 SUPERFAMILY SSF81301 237 371 9.81E-31 T 10-11-2016 A4G23_RS04560 f429925c15bcf04aa5bf090eb7610f53 198 SUPERFAMILY SSF48498 86 197 1.59E-19 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS04560 f429925c15bcf04aa5bf090eb7610f53 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 2.7E-14 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS04560 f429925c15bcf04aa5bf090eb7610f53 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 2.7E-14 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS04560 f429925c15bcf04aa5bf090eb7610f53 198 ProSitePatterns PS01081 TetR-type HTH domain signature. 29 60 - T 10-11-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A4G23_RS04560 f429925c15bcf04aa5bf090eb7610f53 198 SUPERFAMILY SSF46689 14 88 3.24E-22 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS04560 f429925c15bcf04aa5bf090eb7610f53 198 Gene3D G3DSA:1.10.10.60 15 58 1.4E-24 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS04560 f429925c15bcf04aa5bf090eb7610f53 198 Gene3D G3DSA:1.10.357.10 59 198 1.6E-40 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS04560 f429925c15bcf04aa5bf090eb7610f53 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 63 1.4E-23 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS05185 ad8ca82c92d1b14f4a96be7ac8d32c46 544 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 52 466 2.2E-58 T 10-11-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 A4G23_RS05185 ad8ca82c92d1b14f4a96be7ac8d32c46 544 Pfam PF00474 Sodium:solute symporter family 52 467 6.4E-97 T 10-11-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 A4G23_RS07755 ae278f52c94fe03600550fbe93cc7dc1 419 SUPERFAMILY SSF51905 160 323 9.97E-35 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS07755 ae278f52c94fe03600550fbe93cc7dc1 419 SUPERFAMILY SSF51905 2 124 9.97E-35 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS07755 ae278f52c94fe03600550fbe93cc7dc1 419 Gene3D G3DSA:3.50.50.60 96 323 7.0E-42 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS07755 ae278f52c94fe03600550fbe93cc7dc1 419 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 314 3.2E-50 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS07755 ae278f52c94fe03600550fbe93cc7dc1 419 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 251 265 2.4E-11 T 10-11-2016 A4G23_RS07755 ae278f52c94fe03600550fbe93cc7dc1 419 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 2.4E-11 T 10-11-2016 A4G23_RS07755 ae278f52c94fe03600550fbe93cc7dc1 419 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 290 297 2.4E-11 T 10-11-2016 A4G23_RS07755 ae278f52c94fe03600550fbe93cc7dc1 419 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 164 189 2.4E-11 T 10-11-2016 A4G23_RS07755 ae278f52c94fe03600550fbe93cc7dc1 419 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 164 182 4.5E-15 T 10-11-2016 A4G23_RS07755 ae278f52c94fe03600550fbe93cc7dc1 419 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 275 297 4.5E-15 T 10-11-2016 A4G23_RS07755 ae278f52c94fe03600550fbe93cc7dc1 419 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 250 266 4.5E-15 T 10-11-2016 A4G23_RS07755 ae278f52c94fe03600550fbe93cc7dc1 419 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 4.5E-15 T 10-11-2016 A4G23_RS07755 ae278f52c94fe03600550fbe93cc7dc1 419 Gene3D G3DSA:3.50.50.60 2 95 2.5E-20 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS13285 c4d306b64d72994998e91d5c5009c57f 95 Pfam PF06243 Phenylacetic acid degradation B 5 92 2.2E-40 T 10-11-2016 IPR009359 Phenylacetic acid degradation B A4G23_RS13285 c4d306b64d72994998e91d5c5009c57f 95 PIRSF PIRSF030200 1 95 1.7E-44 T 10-11-2016 IPR009359 Phenylacetic acid degradation B A4G23_RS13285 c4d306b64d72994998e91d5c5009c57f 95 TIGRFAM TIGR02157 PA_CoA_Oxy2: phenylacetate-CoA oxygenase, PaaH subunit 6 94 6.5E-44 T 10-11-2016 IPR009359 Phenylacetic acid degradation B A4G23_RS25545 10fb5a52226093f3ae230b688441cce8 278 Pfam PF00582 Universal stress protein family 144 273 1.4E-18 T 10-11-2016 IPR006016 UspA GO:0006950 A4G23_RS25545 10fb5a52226093f3ae230b688441cce8 278 Pfam PF00582 Universal stress protein family 1 132 4.1E-15 T 10-11-2016 IPR006016 UspA GO:0006950 A4G23_RS25545 10fb5a52226093f3ae230b688441cce8 278 Gene3D G3DSA:3.40.50.620 1 132 8.6E-22 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS25545 10fb5a52226093f3ae230b688441cce8 278 Gene3D G3DSA:3.40.50.620 142 273 8.5E-31 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS25545 10fb5a52226093f3ae230b688441cce8 278 PRINTS PR01438 Universal stress protein signature 142 160 2.7E-10 T 10-11-2016 IPR006015 Universal stress protein A A4G23_RS25545 10fb5a52226093f3ae230b688441cce8 278 PRINTS PR01438 Universal stress protein signature 251 273 2.7E-10 T 10-11-2016 IPR006015 Universal stress protein A A4G23_RS25545 10fb5a52226093f3ae230b688441cce8 278 PRINTS PR01438 Universal stress protein signature 233 245 2.7E-10 T 10-11-2016 IPR006015 Universal stress protein A A4G23_RS25545 10fb5a52226093f3ae230b688441cce8 278 SUPERFAMILY SSF52402 143 275 1.0E-26 T 10-11-2016 A4G23_RS25545 10fb5a52226093f3ae230b688441cce8 278 SUPERFAMILY SSF52402 1 135 9.21E-20 T 10-11-2016 A4G23_RS24630 863687a1cafb1cb25332dda18af2d10e 357 Pfam PF00356 Bacterial regulatory proteins, lacI family 14 54 3.6E-12 T 10-11-2016 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4G23_RS24630 863687a1cafb1cb25332dda18af2d10e 357 Gene3D G3DSA:3.40.50.2300 175 340 3.5E-39 T 10-11-2016 A4G23_RS24630 863687a1cafb1cb25332dda18af2d10e 357 SUPERFAMILY SSF53822 84 341 2.36E-49 T 10-11-2016 IPR028082 Periplasmic binding protein-like I A4G23_RS24630 863687a1cafb1cb25332dda18af2d10e 357 Gene3D G3DSA:1.10.260.40 10 54 5.6E-16 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS24630 863687a1cafb1cb25332dda18af2d10e 357 Pfam PF13377 Periplasmic binding protein-like domain 175 338 2.0E-27 T 10-11-2016 A4G23_RS24630 863687a1cafb1cb25332dda18af2d10e 357 SMART SM00354 9 77 6.7E-6 T 10-11-2016 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4G23_RS24630 863687a1cafb1cb25332dda18af2d10e 357 SUPERFAMILY SSF47413 10 56 5.25E-11 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS24630 863687a1cafb1cb25332dda18af2d10e 357 Gene3D G3DSA:3.40.50.2300 84 174 1.5E-15 T 10-11-2016 A4G23_RS04105 fef18b45cce43792dec0addb833bfe67 374 SUPERFAMILY SSF55785 27 81 9.6E-11 T 10-11-2016 IPR000014 PAS domain A4G23_RS04105 fef18b45cce43792dec0addb833bfe67 374 SUPERFAMILY SSF55874 201 364 2.62E-39 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS04105 fef18b45cce43792dec0addb833bfe67 374 Gene3D G3DSA:3.30.450.20 26 81 6.0E-14 T 10-11-2016 A4G23_RS04105 fef18b45cce43792dec0addb833bfe67 374 Gene3D G3DSA:1.10.287.130 136 196 7.6E-16 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS04105 fef18b45cce43792dec0addb833bfe67 374 SUPERFAMILY SSF47384 134 212 1.08E-16 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS04105 fef18b45cce43792dec0addb833bfe67 374 Pfam PF08448 PAS fold 28 75 1.1E-6 T 10-11-2016 IPR013656 PAS fold-4 A4G23_RS04105 fef18b45cce43792dec0addb833bfe67 374 Pfam PF00512 His Kinase A (phospho-acceptor) domain 144 211 1.9E-17 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS04105 fef18b45cce43792dec0addb833bfe67 374 PRINTS PR00344 Bacterial sensor protein C-terminal signature 350 363 1.8E-16 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS04105 fef18b45cce43792dec0addb833bfe67 374 PRINTS PR00344 Bacterial sensor protein C-terminal signature 326 344 1.8E-16 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS04105 fef18b45cce43792dec0addb833bfe67 374 PRINTS PR00344 Bacterial sensor protein C-terminal signature 296 310 1.8E-16 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS04105 fef18b45cce43792dec0addb833bfe67 374 PRINTS PR00344 Bacterial sensor protein C-terminal signature 314 324 1.8E-16 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS04105 fef18b45cce43792dec0addb833bfe67 374 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 257 364 1.6E-24 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS04105 fef18b45cce43792dec0addb833bfe67 374 SMART SM00388 143 211 1.1E-18 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS04105 fef18b45cce43792dec0addb833bfe67 374 SMART SM00387 256 366 9.0E-37 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS04105 fef18b45cce43792dec0addb833bfe67 374 Gene3D G3DSA:3.30.565.10 197 364 1.5E-39 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS01805 6467daea3c5323f4d0377410717bb926 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 51 1.2E-8 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS01805 6467daea3c5323f4d0377410717bb926 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 7 20 1.2E-8 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS01805 6467daea3c5323f4d0377410717bb926 188 SUPERFAMILY SSF48498 74 182 1.14E-21 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS01805 6467daea3c5323f4d0377410717bb926 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 53 3.3E-12 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS01805 6467daea3c5323f4d0377410717bb926 188 SUPERFAMILY SSF46689 3 76 2.67E-16 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS01805 6467daea3c5323f4d0377410717bb926 188 Gene3D G3DSA:1.10.357.10 3 182 1.1E-35 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS01545 a80179b2ae44dc06a69eb3cb9a2b8aaf 159 Pfam PF01453 D-mannose binding lectin 62 127 4.8E-12 T 10-11-2016 IPR001480 Bulb-type lectin domain A4G23_RS01545 a80179b2ae44dc06a69eb3cb9a2b8aaf 159 Gene3D G3DSA:2.90.10.10 50 157 9.3E-29 T 10-11-2016 IPR001480 Bulb-type lectin domain A4G23_RS01545 a80179b2ae44dc06a69eb3cb9a2b8aaf 159 SMART SM00108 50 159 1.3E-12 T 10-11-2016 IPR001480 Bulb-type lectin domain A4G23_RS01545 a80179b2ae44dc06a69eb3cb9a2b8aaf 159 SUPERFAMILY SSF51110 60 157 1.29E-21 T 10-11-2016 IPR001480 Bulb-type lectin domain A4G23_RS26310 4d94facb74706ff8b7c4b5ad16e39888 2197 SUPERFAMILY SSF47336 1052 1121 7.59E-19 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS26310 4d94facb74706ff8b7c4b5ad16e39888 2197 SMART SM00823 Phosphopantetheine attachment site 2108 2177 1.9E-8 T 10-11-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4G23_RS26310 4d94facb74706ff8b7c4b5ad16e39888 2197 SMART SM00823 Phosphopantetheine attachment site 1060 1129 0.024 T 10-11-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4G23_RS26310 4d94facb74706ff8b7c4b5ad16e39888 2197 Pfam PF00501 AMP-binding enzyme 1614 2004 2.3E-86 T 10-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A4G23_RS26310 4d94facb74706ff8b7c4b5ad16e39888 2197 Pfam PF00501 AMP-binding enzyme 516 911 6.0E-96 T 10-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A4G23_RS26310 4d94facb74706ff8b7c4b5ad16e39888 2197 SUPERFAMILY SSF56801 993 1073 4.97E-149 T 10-11-2016 A4G23_RS26310 4d94facb74706ff8b7c4b5ad16e39888 2197 SUPERFAMILY SSF56801 515 965 4.97E-149 T 10-11-2016 A4G23_RS26310 4d94facb74706ff8b7c4b5ad16e39888 2197 Pfam PF00550 Phosphopantetheine attachment site 2113 2172 1.1E-15 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS26310 4d94facb74706ff8b7c4b5ad16e39888 2197 Pfam PF00550 Phosphopantetheine attachment site 1062 1121 2.3E-12 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS26310 4d94facb74706ff8b7c4b5ad16e39888 2197 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1747 1758 - T 10-11-2016 IPR020845 AMP-binding, conserved site A4G23_RS26310 4d94facb74706ff8b7c4b5ad16e39888 2197 SUPERFAMILY SSF52777 1339 1585 1.11E-63 T 10-11-2016 A4G23_RS26310 4d94facb74706ff8b7c4b5ad16e39888 2197 Gene3D G3DSA:3.30.300.30 996 1064 4.5E-38 T 10-11-2016 A4G23_RS26310 4d94facb74706ff8b7c4b5ad16e39888 2197 Gene3D G3DSA:3.30.300.30 1999 2112 4.6E-35 T 10-11-2016 A4G23_RS26310 4d94facb74706ff8b7c4b5ad16e39888 2197 Gene3D G3DSA:3.30.300.30 906 961 4.5E-38 T 10-11-2016 A4G23_RS26310 4d94facb74706ff8b7c4b5ad16e39888 2197 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2132 2147 - T 10-11-2016 IPR006162 Phosphopantetheine attachment site A4G23_RS26310 4d94facb74706ff8b7c4b5ad16e39888 2197 Pfam PF13193 AMP-binding enzyme C-terminal domain 2012 2083 3.5E-10 T 10-11-2016 IPR025110 AMP-binding enzyme C-terminal domain A4G23_RS26310 4d94facb74706ff8b7c4b5ad16e39888 2197 Pfam PF13193 AMP-binding enzyme C-terminal domain 919 1031 3.2E-10 T 10-11-2016 IPR025110 AMP-binding enzyme C-terminal domain A4G23_RS26310 4d94facb74706ff8b7c4b5ad16e39888 2197 SUPERFAMILY SSF52777 1140 1352 5.45E-44 T 10-11-2016 A4G23_RS26310 4d94facb74706ff8b7c4b5ad16e39888 2197 Gene3D G3DSA:1.10.1200.10 2113 2176 2.3E-27 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS26310 4d94facb74706ff8b7c4b5ad16e39888 2197 Gene3D G3DSA:1.10.1200.10 1065 1126 5.9E-26 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS26310 4d94facb74706ff8b7c4b5ad16e39888 2197 SUPERFAMILY SSF52777 179 419 7.45E-51 T 10-11-2016 A4G23_RS26310 4d94facb74706ff8b7c4b5ad16e39888 2197 Gene3D G3DSA:3.40.50.980 1756 1914 1.0E-39 T 10-11-2016 A4G23_RS26310 4d94facb74706ff8b7c4b5ad16e39888 2197 Gene3D G3DSA:3.40.50.980 660 823 3.6E-44 T 10-11-2016 A4G23_RS26310 4d94facb74706ff8b7c4b5ad16e39888 2197 Gene3D G3DSA:2.30.38.10 824 901 2.1E-27 T 10-11-2016 A4G23_RS26310 4d94facb74706ff8b7c4b5ad16e39888 2197 Gene3D G3DSA:2.30.38.10 1915 1994 2.1E-24 T 10-11-2016 A4G23_RS26310 4d94facb74706ff8b7c4b5ad16e39888 2197 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1084 1099 - T 10-11-2016 IPR006162 Phosphopantetheine attachment site A4G23_RS26310 4d94facb74706ff8b7c4b5ad16e39888 2197 SUPERFAMILY SSF56801 1612 2121 2.09E-142 T 10-11-2016 A4G23_RS26310 4d94facb74706ff8b7c4b5ad16e39888 2197 SUPERFAMILY SSF47336 2101 2173 1.27E-19 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS26310 4d94facb74706ff8b7c4b5ad16e39888 2197 SUPERFAMILY SSF52777 11 172 1.33E-45 T 10-11-2016 A4G23_RS26310 4d94facb74706ff8b7c4b5ad16e39888 2197 Pfam PF13745 HxxPF-repeated domain 1472 1562 1.0E-30 T 10-11-2016 A4G23_RS26310 4d94facb74706ff8b7c4b5ad16e39888 2197 Pfam PF13745 HxxPF-repeated domain 312 402 3.3E-17 T 10-11-2016 A4G23_RS26310 4d94facb74706ff8b7c4b5ad16e39888 2197 ProSitePatterns PS00455 Putative AMP-binding domain signature. 651 662 - T 10-11-2016 IPR020845 AMP-binding, conserved site A4G23_RS26310 4d94facb74706ff8b7c4b5ad16e39888 2197 Pfam PF00668 Condensation domain 9 290 9.9E-64 T 10-11-2016 IPR001242 Condensation domain A4G23_RS26310 4d94facb74706ff8b7c4b5ad16e39888 2197 Pfam PF00668 Condensation domain 1144 1449 4.6E-60 T 10-11-2016 IPR001242 Condensation domain A4G23_RS26310 4d94facb74706ff8b7c4b5ad16e39888 2197 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 532 935 1.3E-129 T 10-11-2016 IPR010071 Amino acid adenylation domain A4G23_RS26310 4d94facb74706ff8b7c4b5ad16e39888 2197 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1631 2028 1.1E-125 T 10-11-2016 IPR010071 Amino acid adenylation domain A4G23_RS26310 4d94facb74706ff8b7c4b5ad16e39888 2197 Gene3D G3DSA:3.40.50.980 1614 1755 4.9E-37 T 10-11-2016 A4G23_RS26310 4d94facb74706ff8b7c4b5ad16e39888 2197 Gene3D G3DSA:3.40.50.980 515 659 1.7E-36 T 10-11-2016 A4G23_RS10230 3a5a33ad2d7862ce344ccbdf71f727c1 448 Pfam PF01979 Amidohydrolase family 53 422 5.2E-48 T 10-11-2016 IPR006680 Amidohydrolase-related GO:0016787 A4G23_RS10230 3a5a33ad2d7862ce344ccbdf71f727c1 448 TIGRFAM TIGR02022 hutF: formiminoglutamate deiminase 6 447 3.1E-167 T 10-11-2016 IPR010252 Formiminoglutamate deiminase A4G23_RS10230 3a5a33ad2d7862ce344ccbdf71f727c1 448 SUPERFAMILY SSF51338 329 445 1.36E-10 T 10-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4G23_RS10230 3a5a33ad2d7862ce344ccbdf71f727c1 448 SUPERFAMILY SSF51556 54 370 7.53E-73 T 10-11-2016 IPR032466 Metal-dependent hydrolase A4G23_RS10230 3a5a33ad2d7862ce344ccbdf71f727c1 448 Gene3D G3DSA:3.20.20.140 57 381 3.1E-83 T 10-11-2016 A4G23_RS10230 3a5a33ad2d7862ce344ccbdf71f727c1 448 Gene3D G3DSA:2.30.40.10 19 56 6.9E-4 T 10-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4G23_RS10230 3a5a33ad2d7862ce344ccbdf71f727c1 448 Gene3D G3DSA:2.30.40.10 382 425 6.9E-4 T 10-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4G23_RS10670 01f9af5d0871d3e3c2b0278f85487a4f 290 Gene3D G3DSA:3.20.20.140 10 289 1.7E-78 T 10-11-2016 A4G23_RS10670 01f9af5d0871d3e3c2b0278f85487a4f 290 PIRSF PIRSF005902 11 290 2.3E-67 T 10-11-2016 IPR001130 TatD family GO:0016788 A4G23_RS10670 01f9af5d0871d3e3c2b0278f85487a4f 290 Pfam PF01026 TatD related DNase 20 288 4.2E-69 T 10-11-2016 IPR001130 TatD family GO:0016788 A4G23_RS10670 01f9af5d0871d3e3c2b0278f85487a4f 290 SUPERFAMILY SSF51556 18 289 4.97E-71 T 10-11-2016 IPR032466 Metal-dependent hydrolase A4G23_RS04535 989431740f0380f0fb0746573511c0ab 310 Pfam PF13602 Zinc-binding dehydrogenase 204 305 8.3E-16 T 10-11-2016 A4G23_RS04535 989431740f0380f0fb0746573511c0ab 310 SMART SM00829 10 305 1.1E-28 T 10-11-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A4G23_RS04535 989431740f0380f0fb0746573511c0ab 310 SUPERFAMILY SSF50129 1 152 1.29E-38 T 10-11-2016 IPR011032 GroES-like A4G23_RS04535 989431740f0380f0fb0746573511c0ab 310 SUPERFAMILY SSF51735 119 248 2.96E-34 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS04535 989431740f0380f0fb0746573511c0ab 310 Gene3D G3DSA:3.90.180.10 1 153 6.9E-47 T 10-11-2016 IPR011032 GroES-like A4G23_RS04535 989431740f0380f0fb0746573511c0ab 310 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 90 1.7E-6 T 10-11-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A4G23_RS04535 989431740f0380f0fb0746573511c0ab 310 Gene3D G3DSA:3.40.50.720 154 241 8.7E-18 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS23370 6c991d86c147b01d3146f0b16a0f98b6 1277 Gene3D G3DSA:3.30.300.30 872 937 4.7E-28 T 10-11-2016 A4G23_RS23370 6c991d86c147b01d3146f0b16a0f98b6 1277 Gene3D G3DSA:3.30.300.30 415 470 4.7E-28 T 10-11-2016 A4G23_RS23370 6c991d86c147b01d3146f0b16a0f98b6 1277 Gene3D G3DSA:2.30.38.10 330 410 6.9E-27 T 10-11-2016 A4G23_RS23370 6c991d86c147b01d3146f0b16a0f98b6 1277 Gene3D G3DSA:3.40.50.980 168 325 3.9E-40 T 10-11-2016 A4G23_RS23370 6c991d86c147b01d3146f0b16a0f98b6 1277 Pfam PF00975 Thioesterase domain 1037 1132 1.8E-17 T 10-11-2016 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 A4G23_RS23370 6c991d86c147b01d3146f0b16a0f98b6 1277 Gene3D G3DSA:3.40.50.1820 1208 1272 7.4E-30 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS23370 6c991d86c147b01d3146f0b16a0f98b6 1277 Gene3D G3DSA:3.40.50.1820 1004 1123 7.4E-30 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS23370 6c991d86c147b01d3146f0b16a0f98b6 1277 Pfam PF00550 Phosphopantetheine attachment site 935 999 7.3E-11 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS23370 6c991d86c147b01d3146f0b16a0f98b6 1277 Gene3D G3DSA:3.40.50.980 19 167 1.4E-45 T 10-11-2016 A4G23_RS23370 6c991d86c147b01d3146f0b16a0f98b6 1277 ProSitePatterns PS00012 Phosphopantetheine attachment site. 958 973 - T 10-11-2016 IPR006162 Phosphopantetheine attachment site A4G23_RS23370 6c991d86c147b01d3146f0b16a0f98b6 1277 Gene3D G3DSA:1.10.1200.10 938 1001 4.4E-23 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS23370 6c991d86c147b01d3146f0b16a0f98b6 1277 ProSitePatterns PS00455 Putative AMP-binding domain signature. 161 172 - T 10-11-2016 IPR020845 AMP-binding, conserved site A4G23_RS23370 6c991d86c147b01d3146f0b16a0f98b6 1277 SMART SM00823 Phosphopantetheine attachment site 934 1003 2.7E-8 T 10-11-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4G23_RS23370 6c991d86c147b01d3146f0b16a0f98b6 1277 SUPERFAMILY SSF53474 1000 1270 1.29E-41 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS23370 6c991d86c147b01d3146f0b16a0f98b6 1277 SUPERFAMILY SSF47336 926 999 8.64E-18 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS23370 6c991d86c147b01d3146f0b16a0f98b6 1277 PRINTS PR00154 AMP-binding signature 156 167 8.9E-5 T 10-11-2016 IPR020459 AMP-binding A4G23_RS23370 6c991d86c147b01d3146f0b16a0f98b6 1277 PRINTS PR00154 AMP-binding signature 168 176 8.9E-5 T 10-11-2016 IPR020459 AMP-binding A4G23_RS23370 6c991d86c147b01d3146f0b16a0f98b6 1277 SUPERFAMILY SSF56801 17 475 1.22E-140 T 10-11-2016 A4G23_RS23370 6c991d86c147b01d3146f0b16a0f98b6 1277 SUPERFAMILY SSF56801 867 945 1.22E-140 T 10-11-2016 A4G23_RS23370 6c991d86c147b01d3146f0b16a0f98b6 1277 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 42 443 4.2E-124 T 10-11-2016 IPR010071 Amino acid adenylation domain A4G23_RS23370 6c991d86c147b01d3146f0b16a0f98b6 1277 Pfam PF00501 AMP-binding enzyme 22 420 3.9E-96 T 10-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A4G23_RS12760 899ac7bcbae4e1506b21329b69e1b13d 364 Gene3D G3DSA:2.70.70.10 207 358 1.8E-44 T 10-11-2016 A4G23_RS12760 899ac7bcbae4e1506b21329b69e1b13d 364 Pfam PF01551 Peptidase family M23 258 353 1.0E-27 T 10-11-2016 IPR016047 Peptidase M23 A4G23_RS12760 899ac7bcbae4e1506b21329b69e1b13d 364 SUPERFAMILY SSF51261 180 357 5.07E-44 T 10-11-2016 IPR011055 Duplicated hybrid motif A4G23_RS12760 899ac7bcbae4e1506b21329b69e1b13d 364 PRINTS PR01852 Streptococcal non-M secreted SibA protein signature 173 200 2.3E-8 T 10-11-2016 IPR009148 Streptococcal non-M secreted SibA A4G23_RS12760 899ac7bcbae4e1506b21329b69e1b13d 364 PRINTS PR01852 Streptococcal non-M secreted SibA protein signature 307 331 2.3E-8 T 10-11-2016 IPR009148 Streptococcal non-M secreted SibA A4G23_RS10785 15ffcdffcdb8133f15c4c03921bb99e6 265 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 4 262 4.6E-72 T 10-11-2016 A4G23_RS10785 15ffcdffcdb8133f15c4c03921bb99e6 265 SUPERFAMILY SSF56219 2 263 6.54E-73 T 10-11-2016 IPR005135 Endonuclease/exonuclease/phosphatase A4G23_RS10785 15ffcdffcdb8133f15c4c03921bb99e6 265 Gene3D G3DSA:3.60.10.10 1 263 3.8E-91 T 10-11-2016 IPR005135 Endonuclease/exonuclease/phosphatase A4G23_RS10785 15ffcdffcdb8133f15c4c03921bb99e6 265 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 4 262 1.5E-75 T 10-11-2016 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 A4G23_RS10785 15ffcdffcdb8133f15c4c03921bb99e6 265 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 6 256 2.1E-26 T 10-11-2016 IPR005135 Endonuclease/exonuclease/phosphatase A4G23_RS06615 e2eefbe1a43db63c7e78fc5d1ba17844 245 Pfam PF00072 Response regulator receiver domain 11 125 1.2E-25 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS06615 e2eefbe1a43db63c7e78fc5d1ba17844 245 ProSitePatterns PS00622 LuxR-type HTH domain signature. 194 221 - T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS06615 e2eefbe1a43db63c7e78fc5d1ba17844 245 SUPERFAMILY SSF52172 6 134 7.4E-34 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS06615 e2eefbe1a43db63c7e78fc5d1ba17844 245 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 210 222 2.1E-12 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS06615 e2eefbe1a43db63c7e78fc5d1ba17844 245 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 194 2.1E-12 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS06615 e2eefbe1a43db63c7e78fc5d1ba17844 245 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 194 210 2.1E-12 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS06615 e2eefbe1a43db63c7e78fc5d1ba17844 245 Pfam PF00196 Bacterial regulatory proteins, luxR family 180 234 2.7E-18 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS06615 e2eefbe1a43db63c7e78fc5d1ba17844 245 SUPERFAMILY SSF46894 172 240 8.84E-23 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS06615 e2eefbe1a43db63c7e78fc5d1ba17844 245 SMART SM00448 9 124 4.2E-32 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS06615 e2eefbe1a43db63c7e78fc5d1ba17844 245 SMART SM00421 177 234 3.8E-25 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS06615 e2eefbe1a43db63c7e78fc5d1ba17844 245 Gene3D G3DSA:1.10.10.10 130 241 1.5E-29 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS06615 e2eefbe1a43db63c7e78fc5d1ba17844 245 Gene3D G3DSA:3.40.50.2300 4 129 1.1E-36 T 10-11-2016 A4G23_RS03395 830f4773208dad834963205126bdae33 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 170 1.2E-5 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS03395 830f4773208dad834963205126bdae33 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.2E-5 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS03395 830f4773208dad834963205126bdae33 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 46 57 1.2E-5 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS03395 830f4773208dad834963205126bdae33 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 103 122 1.2E-5 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS03395 830f4773208dad834963205126bdae33 251 SUPERFAMILY SSF51735 3 212 5.3E-40 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS03395 830f4773208dad834963205126bdae33 251 Gene3D G3DSA:3.40.50.720 1 205 8.4E-37 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS03395 830f4773208dad834963205126bdae33 251 Pfam PF13460 NAD(P)H-binding 8 131 6.3E-18 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS11145 5b409c7ededc215df593440ef70d1405 237 Pfam PF13419 Haloacid dehalogenase-like hydrolase 18 199 4.0E-29 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS11145 5b409c7ededc215df593440ef70d1405 237 Gene3D G3DSA:1.10.150.240 32 97 1.8E-9 T 10-11-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 A4G23_RS11145 5b409c7ededc215df593440ef70d1405 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 145 161 1.9E-9 T 10-11-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A4G23_RS11145 5b409c7ededc215df593440ef70d1405 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 15 26 1.9E-9 T 10-11-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A4G23_RS11145 5b409c7ededc215df593440ef70d1405 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 114 127 1.9E-9 T 10-11-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A4G23_RS11145 5b409c7ededc215df593440ef70d1405 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 188 201 1.9E-9 T 10-11-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A4G23_RS11145 5b409c7ededc215df593440ef70d1405 237 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 86 199 2.2E-9 T 10-11-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A4G23_RS11145 5b409c7ededc215df593440ef70d1405 237 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 117 193 9.9E-9 T 10-11-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A4G23_RS11145 5b409c7ededc215df593440ef70d1405 237 Gene3D G3DSA:3.40.50.1000 98 222 3.0E-39 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS11145 5b409c7ededc215df593440ef70d1405 237 Gene3D G3DSA:3.40.50.1000 12 31 3.0E-39 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS11145 5b409c7ededc215df593440ef70d1405 237 SUPERFAMILY SSF56784 15 223 3.45E-49 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS09235 9bdca80abe82109c85e3085f2f5eae86 560 Gene3D G3DSA:3.30.450.20 2 97 2.0E-10 T 10-11-2016 A4G23_RS09235 9bdca80abe82109c85e3085f2f5eae86 560 Gene3D G3DSA:3.20.20.450 302 555 9.8E-107 T 10-11-2016 IPR001633 EAL domain A4G23_RS09235 9bdca80abe82109c85e3085f2f5eae86 560 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 108 286 1.3E-25 T 10-11-2016 IPR000160 GGDEF domain A4G23_RS09235 9bdca80abe82109c85e3085f2f5eae86 560 SUPERFAMILY SSF55073 117 290 2.98E-35 T 10-11-2016 IPR029787 Nucleotide cyclase A4G23_RS09235 9bdca80abe82109c85e3085f2f5eae86 560 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 1 107 1.6E-7 T 10-11-2016 IPR000014 PAS domain A4G23_RS09235 9bdca80abe82109c85e3085f2f5eae86 560 Pfam PF00563 EAL domain 305 545 7.9E-66 T 10-11-2016 IPR001633 EAL domain A4G23_RS09235 9bdca80abe82109c85e3085f2f5eae86 560 SMART SM00052 298 550 9.2E-103 T 10-11-2016 IPR001633 EAL domain A4G23_RS09235 9bdca80abe82109c85e3085f2f5eae86 560 SUPERFAMILY SSF55785 2 108 1.61E-12 T 10-11-2016 IPR000014 PAS domain A4G23_RS09235 9bdca80abe82109c85e3085f2f5eae86 560 Gene3D G3DSA:3.30.70.270 112 293 1.0E-45 T 10-11-2016 A4G23_RS09235 9bdca80abe82109c85e3085f2f5eae86 560 SUPERFAMILY SSF141868 305 555 4.45E-81 T 10-11-2016 IPR001633 EAL domain A4G23_RS09235 9bdca80abe82109c85e3085f2f5eae86 560 Pfam PF08448 PAS fold 2 102 1.6E-7 T 10-11-2016 IPR013656 PAS fold-4 A4G23_RS09235 9bdca80abe82109c85e3085f2f5eae86 560 SMART SM00267 100 288 1.0E-42 T 10-11-2016 IPR000160 GGDEF domain A4G23_RS09235 9bdca80abe82109c85e3085f2f5eae86 560 Pfam PF00990 Diguanylate cyclase, GGDEF domain 112 283 1.2E-33 T 10-11-2016 IPR000160 GGDEF domain A4G23_RS22470 64bf6a72179e7f93e2ef1472135c3b00 315 SUPERFAMILY SSF51735 2 227 1.61E-28 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS22470 64bf6a72179e7f93e2ef1472135c3b00 315 TIGRFAM TIGR01746 Thioester-redct: thioester reductase domain 1 310 4.3E-70 T 10-11-2016 IPR010080 Thioester reductase-like domain A4G23_RS22470 64bf6a72179e7f93e2ef1472135c3b00 315 Gene3D G3DSA:3.40.50.720 3 237 9.5E-33 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS22470 64bf6a72179e7f93e2ef1472135c3b00 315 Pfam PF07993 Male sterility protein 2 181 8.4E-43 T 10-11-2016 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 A4G23_RS14695 77fcc6085b80c1f7d7fcd8660508fa00 202 Pfam PF01965 DJ-1/PfpI family 11 172 4.4E-26 T 10-11-2016 IPR002818 DJ-1/PfpI A4G23_RS14695 77fcc6085b80c1f7d7fcd8660508fa00 202 SUPERFAMILY SSF52317 11 175 1.98E-30 T 10-11-2016 IPR029062 Class I glutamine amidotransferase-like A4G23_RS14695 77fcc6085b80c1f7d7fcd8660508fa00 202 Gene3D G3DSA:3.40.50.880 10 179 4.6E-33 T 10-11-2016 IPR029062 Class I glutamine amidotransferase-like A4G23_RS17270 55a1ca6c49a17509a2d1eeb55f262b6d 381 Gene3D G3DSA:3.40.50.300 72 298 3.3E-79 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS17270 55a1ca6c49a17509a2d1eeb55f262b6d 381 ProSitePatterns PS00211 ABC transporters family signature. 198 212 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS17270 55a1ca6c49a17509a2d1eeb55f262b6d 381 SUPERFAMILY SSF52540 73 302 9.23E-77 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS17270 55a1ca6c49a17509a2d1eeb55f262b6d 381 SMART SM00382 86 283 8.8E-19 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS17270 55a1ca6c49a17509a2d1eeb55f262b6d 381 Pfam PF00005 ABC transporter 78 225 2.6E-32 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS17270 55a1ca6c49a17509a2d1eeb55f262b6d 381 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 70 354 2.5E-105 T 10-11-2016 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 A4G23_RS15530 e5054778d455e2c08e52d2930d043e28 269 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 160 264 1.5E-37 T 10-11-2016 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 A4G23_RS15530 e5054778d455e2c08e52d2930d043e28 269 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 5 264 1.1E-82 T 10-11-2016 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 A4G23_RS15530 e5054778d455e2c08e52d2930d043e28 269 PIRSF PIRSF000193 2 267 1.1E-78 T 10-11-2016 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 A4G23_RS15530 e5054778d455e2c08e52d2930d043e28 269 Gene3D G3DSA:1.10.3730.10 159 264 1.1E-40 T 10-11-2016 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 A4G23_RS15530 e5054778d455e2c08e52d2930d043e28 269 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 220 242 - T 10-11-2016 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 A4G23_RS15530 e5054778d455e2c08e52d2930d043e28 269 Gene3D G3DSA:3.40.50.720 2 157 1.6E-44 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS15530 e5054778d455e2c08e52d2930d043e28 269 SUPERFAMILY SSF48179 159 265 3.74E-35 T 10-11-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A4G23_RS15530 e5054778d455e2c08e52d2930d043e28 269 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 5 97 1.7E-22 T 10-11-2016 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal A4G23_RS15530 e5054778d455e2c08e52d2930d043e28 269 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 3 264 27.279 T 10-11-2016 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 A4G23_RS15530 e5054778d455e2c08e52d2930d043e28 269 SUPERFAMILY SSF51735 4 158 5.31E-36 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS22735 76993d194869cf46d8e6b280568b2e1d 1266 Pfam PF13809 Tubulin like 8 397 2.3E-80 T 10-11-2016 IPR025904 Tubulin-like A4G23_RS07760 ba9e1f57f05f36e9dd94eee4f3e64056 840 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 12 298 1.5E-48 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS07760 ba9e1f57f05f36e9dd94eee4f3e64056 840 Gene3D G3DSA:3.50.50.60 238 323 6.9E-19 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS07760 ba9e1f57f05f36e9dd94eee4f3e64056 840 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 629 766 8.9E-24 T 10-11-2016 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4G23_RS07760 ba9e1f57f05f36e9dd94eee4f3e64056 840 SUPERFAMILY SSF55124 510 638 2.13E-25 T 10-11-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4G23_RS07760 ba9e1f57f05f36e9dd94eee4f3e64056 840 PRINTS PR00397 Sirohaem Fe-binding site signature 676 694 4.3E-6 T 10-11-2016 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4G23_RS07760 ba9e1f57f05f36e9dd94eee4f3e64056 840 PRINTS PR00397 Sirohaem Fe-binding site signature 633 651 4.3E-6 T 10-11-2016 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4G23_RS07760 ba9e1f57f05f36e9dd94eee4f3e64056 840 Gene3D G3DSA:3.30.413.10 629 765 4.4E-38 T 10-11-2016 A4G23_RS07760 ba9e1f57f05f36e9dd94eee4f3e64056 840 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 557 618 1.7E-11 T 10-11-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4G23_RS07760 ba9e1f57f05f36e9dd94eee4f3e64056 840 SUPERFAMILY SSF51905 10 195 1.37E-40 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS07760 ba9e1f57f05f36e9dd94eee4f3e64056 840 SUPERFAMILY SSF51905 152 319 8.64E-27 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS07760 ba9e1f57f05f36e9dd94eee4f3e64056 840 PIRSF PIRSF037149 5 830 0.0 T 10-11-2016 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 A4G23_RS07760 ba9e1f57f05f36e9dd94eee4f3e64056 840 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 154 172 4.5E-17 T 10-11-2016 A4G23_RS07760 ba9e1f57f05f36e9dd94eee4f3e64056 840 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 268 290 4.5E-17 T 10-11-2016 A4G23_RS07760 ba9e1f57f05f36e9dd94eee4f3e64056 840 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 109 127 4.5E-17 T 10-11-2016 A4G23_RS07760 ba9e1f57f05f36e9dd94eee4f3e64056 840 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 13 32 4.5E-17 T 10-11-2016 A4G23_RS07760 ba9e1f57f05f36e9dd94eee4f3e64056 840 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 241 257 4.5E-17 T 10-11-2016 A4G23_RS07760 ba9e1f57f05f36e9dd94eee4f3e64056 840 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 676 692 - T 10-11-2016 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4G23_RS07760 ba9e1f57f05f36e9dd94eee4f3e64056 840 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 12 34 1.1E-8 T 10-11-2016 A4G23_RS07760 ba9e1f57f05f36e9dd94eee4f3e64056 840 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 283 290 1.1E-8 T 10-11-2016 A4G23_RS07760 ba9e1f57f05f36e9dd94eee4f3e64056 840 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 242 256 1.1E-8 T 10-11-2016 A4G23_RS07760 ba9e1f57f05f36e9dd94eee4f3e64056 840 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 154 179 1.1E-8 T 10-11-2016 A4G23_RS07760 ba9e1f57f05f36e9dd94eee4f3e64056 840 Gene3D G3DSA:3.50.50.60 9 110 4.0E-19 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS07760 ba9e1f57f05f36e9dd94eee4f3e64056 840 Pfam PF04324 BFD-like [2Fe-2S] binding domain 427 469 1.5E-7 T 10-11-2016 IPR007419 BFD-like [2Fe-2S]-binding domain A4G23_RS07760 ba9e1f57f05f36e9dd94eee4f3e64056 840 SUPERFAMILY SSF56014 630 802 2.36E-52 T 10-11-2016 A4G23_RS07760 ba9e1f57f05f36e9dd94eee4f3e64056 840 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 13 796 0.0 T 10-11-2016 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 A4G23_RS07760 ba9e1f57f05f36e9dd94eee4f3e64056 840 Gene3D G3DSA:3.50.50.60 111 237 2.8E-39 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS14610 a7166fef84b9266f00943c5b0d00d5d5 299 Pfam PF00182 Chitinase class I 97 299 6.2E-43 T 10-11-2016 IPR000726 Glycoside hydrolase, family 19, catalytic GO:0004568|GO:0006032|GO:0016998 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 A4G23_RS14610 a7166fef84b9266f00943c5b0d00d5d5 299 Gene3D G3DSA:3.30.20.10 164 218 9.3E-25 T 10-11-2016 A4G23_RS14610 a7166fef84b9266f00943c5b0d00d5d5 299 Pfam PF02839 Carbohydrate binding domain 34 72 2.7E-8 T 10-11-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 A4G23_RS14610 a7166fef84b9266f00943c5b0d00d5d5 299 Gene3D G3DSA:1.10.530.10 97 155 2.3E-54 T 10-11-2016 A4G23_RS14610 a7166fef84b9266f00943c5b0d00d5d5 299 Gene3D G3DSA:1.10.530.10 219 299 2.3E-54 T 10-11-2016 A4G23_RS14610 a7166fef84b9266f00943c5b0d00d5d5 299 SMART SM00495 33 75 6.3E-11 T 10-11-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 A4G23_RS14610 a7166fef84b9266f00943c5b0d00d5d5 299 SUPERFAMILY SSF53955 96 299 3.37E-66 T 10-11-2016 IPR023346 Lysozyme-like domain A4G23_RS14610 a7166fef84b9266f00943c5b0d00d5d5 299 SUPERFAMILY SSF51055 24 78 2.55E-14 T 10-11-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 A4G23_RS14610 a7166fef84b9266f00943c5b0d00d5d5 299 Gene3D G3DSA:2.10.10.20 30 79 2.0E-17 T 10-11-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 A4G23_RS14610 a7166fef84b9266f00943c5b0d00d5d5 299 PIRSF PIRSF001060 2 299 5.8E-85 T 10-11-2016 IPR016283 Glycoside hydrolase, family 19 GO:0004568|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 A4G23_RS04585 5879d8a745ffe153473ea1681efe08e1 153 Gene3D G3DSA:3.10.129.10 12 149 3.8E-38 T 10-11-2016 IPR029069 HotDog domain A4G23_RS04585 5879d8a745ffe153473ea1681efe08e1 153 Pfam PF01575 MaoC like domain 15 130 5.6E-27 T 10-11-2016 IPR002539 MaoC-like domain A4G23_RS04585 5879d8a745ffe153473ea1681efe08e1 153 SUPERFAMILY SSF54637 11 149 5.81E-40 T 10-11-2016 IPR029069 HotDog domain A4G23_RS25575 8be38baa9bf0aea86f159f3d430ffe37 286 SUPERFAMILY SSF52540 18 247 4.46E-55 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS25575 8be38baa9bf0aea86f159f3d430ffe37 286 Gene3D G3DSA:3.40.50.300 20 255 1.0E-57 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS25575 8be38baa9bf0aea86f159f3d430ffe37 286 Pfam PF00005 ABC transporter 34 182 4.3E-25 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS25575 8be38baa9bf0aea86f159f3d430ffe37 286 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS25575 8be38baa9bf0aea86f159f3d430ffe37 286 SMART SM00382 42 231 1.9E-17 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS05975 7fbb1f09f0928352b1ecd9a63ab823d9 330 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 128 140 - T 10-11-2016 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 A4G23_RS05975 7fbb1f09f0928352b1ecd9a63ab823d9 330 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 1 248 14.414 T 10-11-2016 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 A4G23_RS05975 7fbb1f09f0928352b1ecd9a63ab823d9 330 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 2 242 4.5E-62 T 10-11-2016 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 A4G23_RS05975 7fbb1f09f0928352b1ecd9a63ab823d9 330 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 2 243 5.3E-41 T 10-11-2016 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 A4G23_RS13010 d6d2e6a331b15b62770ab12a976c345f 441 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 402 437 0.002 T 10-11-2016 IPR019931 LPXTG cell wall anchor domain A4G23_RS07905 8b9a84faa4488561c9dc1c9862cdc98d 301 Pfam PF12706 Beta-lactamase superfamily domain 180 263 2.1E-10 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS07905 8b9a84faa4488561c9dc1c9862cdc98d 301 Gene3D G3DSA:3.60.15.10 5 300 2.4E-71 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS07905 8b9a84faa4488561c9dc1c9862cdc98d 301 Pfam PF00753 Metallo-beta-lactamase superfamily 20 118 1.9E-14 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS07905 8b9a84faa4488561c9dc1c9862cdc98d 301 Hamap MF_01818 Ribonuclease BN [rbn]. 4 297 30.361 T 10-11-2016 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 A4G23_RS07905 8b9a84faa4488561c9dc1c9862cdc98d 301 SUPERFAMILY SSF56281 5 296 1.48E-62 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS07905 8b9a84faa4488561c9dc1c9862cdc98d 301 SMART SM00849 21 197 0.0052 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS22215 3d8dc8e35ef19e043de4bf35008a7a5c 246 Pfam PF01738 Dienelactone hydrolase family 21 236 4.1E-28 T 10-11-2016 IPR002925 Dienelactone hydrolase GO:0016787 A4G23_RS22215 3d8dc8e35ef19e043de4bf35008a7a5c 246 Gene3D G3DSA:3.40.50.1820 4 235 2.7E-45 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS22215 3d8dc8e35ef19e043de4bf35008a7a5c 246 SUPERFAMILY SSF53474 6 238 1.5E-37 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS18855 168b14bb19c5dd737c222f7cf161ebdc 362 Gene3D G3DSA:2.30.42.10 131 194 7.6E-15 T 10-11-2016 IPR001478 PDZ domain GO:0005515 A4G23_RS18855 168b14bb19c5dd737c222f7cf161ebdc 362 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 253 343 1.3E-7 T 10-11-2016 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 A4G23_RS18855 168b14bb19c5dd737c222f7cf161ebdc 362 Gene3D G3DSA:3.30.230.10 251 344 5.6E-21 T 10-11-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A4G23_RS18855 168b14bb19c5dd737c222f7cf161ebdc 362 Pfam PF13180 PDZ domain 138 193 4.4E-9 T 10-11-2016 IPR001478 PDZ domain GO:0005515 A4G23_RS18855 168b14bb19c5dd737c222f7cf161ebdc 362 SUPERFAMILY SSF50156 140 254 3.08E-15 T 10-11-2016 IPR001478 PDZ domain GO:0005515 A4G23_RS18855 168b14bb19c5dd737c222f7cf161ebdc 362 SMART SM00228 131 197 8.5E-10 T 10-11-2016 IPR001478 PDZ domain GO:0005515 A4G23_RS18855 168b14bb19c5dd737c222f7cf161ebdc 362 SUPERFAMILY SSF54211 234 345 2.31E-19 T 10-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold A4G23_RS15375 eb88eb956555fb8aeac68479818ee8cf 315 Pfam PF10728 Domain of unknown function (DUF2520) 145 271 1.0E-37 T 10-11-2016 IPR018931 Domain of unknown function DUF2520 A4G23_RS15375 eb88eb956555fb8aeac68479818ee8cf 315 Gene3D G3DSA:3.40.50.720 12 175 5.5E-35 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS15375 eb88eb956555fb8aeac68479818ee8cf 315 Gene3D G3DSA:1.10.1040.20 178 275 7.1E-31 T 10-11-2016 IPR018931 Domain of unknown function DUF2520 A4G23_RS15375 eb88eb956555fb8aeac68479818ee8cf 315 Pfam PF10727 Rossmann-like domain 5 128 4.7E-43 T 10-11-2016 IPR019665 Putative oxidoreductase/dehydrogenase, Rossmann-like domain A4G23_RS15375 eb88eb956555fb8aeac68479818ee8cf 315 SUPERFAMILY SSF48179 178 277 5.1E-24 T 10-11-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A4G23_RS15375 eb88eb956555fb8aeac68479818ee8cf 315 SUPERFAMILY SSF51735 14 176 5.51E-27 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS25665 e7e7b78b27e6fe86edfdf803b9fac768 644 Gene3D G3DSA:1.25.40.10 253 427 1.1E-7 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS25665 e7e7b78b27e6fe86edfdf803b9fac768 644 Gene3D G3DSA:1.25.40.10 56 124 1.1E-7 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS25665 e7e7b78b27e6fe86edfdf803b9fac768 644 Gene3D G3DSA:1.25.40.10 470 567 1.1E-7 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS25665 e7e7b78b27e6fe86edfdf803b9fac768 644 SUPERFAMILY SSF46894 565 629 1.7E-17 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS25665 e7e7b78b27e6fe86edfdf803b9fac768 644 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 589 605 1.6E-9 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS25665 e7e7b78b27e6fe86edfdf803b9fac768 644 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 575 589 1.6E-9 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS25665 e7e7b78b27e6fe86edfdf803b9fac768 644 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 605 617 1.6E-9 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS25665 e7e7b78b27e6fe86edfdf803b9fac768 644 ProSitePatterns PS00622 LuxR-type HTH domain signature. 589 616 - T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS25665 e7e7b78b27e6fe86edfdf803b9fac768 644 Gene3D G3DSA:1.10.10.10 568 629 2.4E-21 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS25665 e7e7b78b27e6fe86edfdf803b9fac768 644 SMART SM00421 572 629 7.4E-21 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS25665 e7e7b78b27e6fe86edfdf803b9fac768 644 Pfam PF00196 Bacterial regulatory proteins, luxR family 574 628 6.3E-15 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS16540 636fe20a1d5f0bb65c20c4d2d6877731 359 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 72 4.9E-15 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS16540 636fe20a1d5f0bb65c20c4d2d6877731 359 SMART SM00345 13 72 5.3E-14 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS16540 636fe20a1d5f0bb65c20c4d2d6877731 359 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 199 350 2.5E-14 T 10-11-2016 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 A4G23_RS16540 636fe20a1d5f0bb65c20c4d2d6877731 359 SUPERFAMILY SSF48498 205 355 2.22E-22 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS16540 636fe20a1d5f0bb65c20c4d2d6877731 359 Gene3D G3DSA:1.10.10.60 127 190 1.5E-23 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS16540 636fe20a1d5f0bb65c20c4d2d6877731 359 Gene3D G3DSA:1.10.10.10 10 78 1.4E-22 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS16540 636fe20a1d5f0bb65c20c4d2d6877731 359 SUPERFAMILY SSF46785 7 76 1.84E-19 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS16540 636fe20a1d5f0bb65c20c4d2d6877731 359 SUPERFAMILY SSF46689 132 194 6.31E-13 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS16540 636fe20a1d5f0bb65c20c4d2d6877731 359 Pfam PF00440 Bacterial regulatory proteins, tetR family 143 185 2.4E-5 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS16540 636fe20a1d5f0bb65c20c4d2d6877731 359 Gene3D G3DSA:1.10.357.10 191 353 2.2E-30 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS03735 5f9a96b192eba7df66a71f3b4c220f59 250 Gene3D G3DSA:1.10.10.200 1 79 8.8E-33 T 10-11-2016 IPR017856 Integrase, N-terminal zinc-binding domain-like A4G23_RS03735 5f9a96b192eba7df66a71f3b4c220f59 250 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 240 35.074 T 10-11-2016 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS03735 5f9a96b192eba7df66a71f3b4c220f59 250 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 238 2.3E-99 T 10-11-2016 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS03735 5f9a96b192eba7df66a71f3b4c220f59 250 Pfam PF01709 Transcriptional regulator 5 238 1.6E-89 T 10-11-2016 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS03735 5f9a96b192eba7df66a71f3b4c220f59 250 Gene3D G3DSA:3.30.1270.10 213 248 6.1E-40 T 10-11-2016 IPR026563 Transcriptional regulator TACO1-like, domain 2 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS03735 5f9a96b192eba7df66a71f3b4c220f59 250 Gene3D G3DSA:3.30.1270.10 83 137 6.1E-40 T 10-11-2016 IPR026563 Transcriptional regulator TACO1-like, domain 2 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS03735 5f9a96b192eba7df66a71f3b4c220f59 250 SUPERFAMILY SSF75625 3 247 3.53E-91 T 10-11-2016 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS03735 5f9a96b192eba7df66a71f3b4c220f59 250 Gene3D G3DSA:3.30.70.980 138 205 2.2E-24 T 10-11-2016 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS14875 dd893bbda854de7026742e9c73e2e480 449 Hamap MF_01844 Na(+)/H(+) antiporter NhaA [nhaA]. 7 388 21.037 T 10-11-2016 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 A4G23_RS14875 dd893bbda854de7026742e9c73e2e480 449 Gene3D G3DSA:1.20.1530.10 9 388 6.3E-140 T 10-11-2016 IPR023171 Na/H antiporter domain A4G23_RS14875 dd893bbda854de7026742e9c73e2e480 449 Pfam PF06965 Na+/H+ antiporter 1 10 382 9.4E-137 T 10-11-2016 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 A4G23_RS14875 dd893bbda854de7026742e9c73e2e480 449 TIGRFAM TIGR00773 NhaA: Na+/H+ antiporter NhaA 12 381 4.1E-100 T 10-11-2016 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 A4G23_RS06890 71289158a1c33b463643061f7fdd4ee8 453 SUPERFAMILY SSF54368 8 103 3.27E-30 T 10-11-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4G23_RS06890 71289158a1c33b463643061f7fdd4ee8 453 Gene3D G3DSA:3.10.20.70 6 107 4.4E-39 T 10-11-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4G23_RS06890 71289158a1c33b463643061f7fdd4ee8 453 SMART SM01230 104 363 2.9E-122 T 10-11-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4G23_RS06890 71289158a1c33b463643061f7fdd4ee8 453 Pfam PF00120 Glutamine synthetase, catalytic domain 105 448 7.6E-125 T 10-11-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4G23_RS06890 71289158a1c33b463643061f7fdd4ee8 453 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 232 247 - T 10-11-2016 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 A4G23_RS06890 71289158a1c33b463643061f7fdd4ee8 453 SUPERFAMILY SSF55931 106 450 2.75E-113 T 10-11-2016 A4G23_RS06890 71289158a1c33b463643061f7fdd4ee8 453 Gene3D G3DSA:3.30.590.10 108 440 1.5E-111 T 10-11-2016 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 A4G23_RS06890 71289158a1c33b463643061f7fdd4ee8 453 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 98 1.2E-28 T 10-11-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4G23_RS06890 71289158a1c33b463643061f7fdd4ee8 453 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 8 448 8.8E-131 T 10-11-2016 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4G23_RS17020 a08c5a95b10fe7be593ac39313bce747 620 SUPERFAMILY SSF51905 502 563 9.26E-50 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS17020 a08c5a95b10fe7be593ac39313bce747 620 SUPERFAMILY SSF51905 28 185 9.26E-50 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS17020 a08c5a95b10fe7be593ac39313bce747 620 SUPERFAMILY SSF51905 221 336 9.26E-50 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS17020 a08c5a95b10fe7be593ac39313bce747 620 Pfam PF05199 GMC oxidoreductase 500 557 1.0E-12 T 10-11-2016 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 A4G23_RS17020 a08c5a95b10fe7be593ac39313bce747 620 Gene3D G3DSA:3.50.50.60 229 334 1.5E-84 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS17020 a08c5a95b10fe7be593ac39313bce747 620 Gene3D G3DSA:3.50.50.60 496 564 1.5E-84 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS17020 a08c5a95b10fe7be593ac39313bce747 620 Gene3D G3DSA:3.50.50.60 446 447 1.5E-84 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS17020 a08c5a95b10fe7be593ac39313bce747 620 Gene3D G3DSA:3.50.50.60 30 151 1.5E-84 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS17020 a08c5a95b10fe7be593ac39313bce747 620 Pfam PF00732 GMC oxidoreductase 31 311 3.1E-10 T 10-11-2016 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 A4G23_RS02455 b48d4d49a31f4b4025a0fc50860f23d1 447 Gene3D G3DSA:3.40.190.10 172 368 1.2E-31 T 10-11-2016 A4G23_RS02455 b48d4d49a31f4b4025a0fc50860f23d1 447 SUPERFAMILY SSF53850 40 441 3.95E-61 T 10-11-2016 A4G23_RS02455 b48d4d49a31f4b4025a0fc50860f23d1 447 Pfam PF01547 Bacterial extracellular solute-binding protein 54 352 9.0E-26 T 10-11-2016 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 A4G23_RS02455 b48d4d49a31f4b4025a0fc50860f23d1 447 Gene3D G3DSA:3.40.190.10 50 171 1.9E-21 T 10-11-2016 A4G23_RS08420 44b0bd3d9f8abb7c5a51139f95f8ac10 1098 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 205 216 - T 10-11-2016 IPR023827 Peptidase S8, subtilisin, Asp-active site A4G23_RS08420 44b0bd3d9f8abb7c5a51139f95f8ac10 1098 SUPERFAMILY SSF52743 361 641 1.96E-56 T 10-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4G23_RS08420 44b0bd3d9f8abb7c5a51139f95f8ac10 1098 SUPERFAMILY SSF52743 187 219 1.96E-56 T 10-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4G23_RS08420 44b0bd3d9f8abb7c5a51139f95f8ac10 1098 Pfam PF00082 Subtilase family 200 631 2.4E-57 T 10-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4G23_RS08420 44b0bd3d9f8abb7c5a51139f95f8ac10 1098 Gene3D G3DSA:2.60.120.380 972 1024 9.8E-5 T 10-11-2016 A4G23_RS08420 44b0bd3d9f8abb7c5a51139f95f8ac10 1098 PRINTS PR00723 Subtilisin serine protease family (S8) signature 380 393 1.2E-16 T 10-11-2016 IPR015500 Peptidase S8, subtilisin-related A4G23_RS08420 44b0bd3d9f8abb7c5a51139f95f8ac10 1098 PRINTS PR00723 Subtilisin serine protease family (S8) signature 577 593 1.2E-16 T 10-11-2016 IPR015500 Peptidase S8, subtilisin-related A4G23_RS08420 44b0bd3d9f8abb7c5a51139f95f8ac10 1098 PRINTS PR00723 Subtilisin serine protease family (S8) signature 200 219 1.2E-16 T 10-11-2016 IPR015500 Peptidase S8, subtilisin-related A4G23_RS08420 44b0bd3d9f8abb7c5a51139f95f8ac10 1098 Gene3D G3DSA:3.40.50.200 189 246 2.0E-67 T 10-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4G23_RS08420 44b0bd3d9f8abb7c5a51139f95f8ac10 1098 Gene3D G3DSA:3.40.50.200 384 639 2.0E-67 T 10-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4G23_RS08420 44b0bd3d9f8abb7c5a51139f95f8ac10 1098 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 578 588 - T 10-11-2016 IPR023828 Peptidase S8, subtilisin, Ser-active site A4G23_RS25600 c2148526f5afa2bc8432de0188a9a3c4 457 Pfam PF06863 Protein of unknown function (DUF1254) 78 172 5.5E-19 T 10-11-2016 IPR010679 Domain of unknown function DUF1254 A4G23_RS25600 c2148526f5afa2bc8432de0188a9a3c4 457 Pfam PF06742 Protein of unknown function (DUF1214) 336 441 4.9E-23 T 10-11-2016 IPR010621 Domain of unknown function DUF1214 A4G23_RS25600 c2148526f5afa2bc8432de0188a9a3c4 457 SUPERFAMILY SSF160935 6 457 1.96E-120 T 10-11-2016 A4G23_RS25600 c2148526f5afa2bc8432de0188a9a3c4 457 Gene3D G3DSA:1.10.3360.10 191 279 2.5E-33 T 10-11-2016 IPR023289 VPA0735-like domain A4G23_RS25600 c2148526f5afa2bc8432de0188a9a3c4 457 Gene3D G3DSA:2.60.40.1610 66 190 1.7E-44 T 10-11-2016 IPR010679 Domain of unknown function DUF1254 A4G23_RS25600 c2148526f5afa2bc8432de0188a9a3c4 457 Gene3D G3DSA:2.60.120.600 287 457 1.7E-44 T 10-11-2016 IPR010621 Domain of unknown function DUF1214 A4G23_RS16225 b82011b0c8204b3454f09e625e79f376 517 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 144 163 9.8E-40 T 10-11-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16225 b82011b0c8204b3454f09e625e79f376 517 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 397 423 9.8E-40 T 10-11-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16225 b82011b0c8204b3454f09e625e79f376 517 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 246 270 9.8E-40 T 10-11-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16225 b82011b0c8204b3454f09e625e79f376 517 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 340 359 9.8E-40 T 10-11-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16225 b82011b0c8204b3454f09e625e79f376 517 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 174 198 9.8E-40 T 10-11-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16225 b82011b0c8204b3454f09e625e79f376 517 Pfam PF00361 Proton-conducting membrane transporter 140 424 2.1E-59 T 10-11-2016 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16225 b82011b0c8204b3454f09e625e79f376 517 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 5 513 9.4E-165 T 10-11-2016 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS05080 129b1a2601893ca87019b03e0f36e396 900 ProSitePatterns PS00211 ABC transporters family signature. 471 485 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS05080 129b1a2601893ca87019b03e0f36e396 900 Pfam PF16697 Inner membrane component of T3SS, cytoplasmic domain 9 85 1.5E-15 T 10-11-2016 IPR032030 YscD, cytoplasmic domain A4G23_RS05080 129b1a2601893ca87019b03e0f36e396 900 Gene3D G3DSA:3.40.50.300 332 562 3.8E-68 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05080 129b1a2601893ca87019b03e0f36e396 900 SUPERFAMILY SSF49879 183 342 2.1E-27 T 10-11-2016 IPR008984 SMAD/FHA domain GO:0005515 A4G23_RS05080 129b1a2601893ca87019b03e0f36e396 900 SUPERFAMILY SSF49879 9 87 2.68E-22 T 10-11-2016 IPR008984 SMAD/FHA domain GO:0005515 A4G23_RS05080 129b1a2601893ca87019b03e0f36e396 900 Gene3D G3DSA:2.60.200.20 9 85 1.3E-22 T 10-11-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 A4G23_RS05080 129b1a2601893ca87019b03e0f36e396 900 Pfam PF00498 FHA domain 248 314 8.7E-16 T 10-11-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 A4G23_RS05080 129b1a2601893ca87019b03e0f36e396 900 SUPERFAMILY SSF52540 329 571 6.58E-60 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05080 129b1a2601893ca87019b03e0f36e396 900 Pfam PF00005 ABC transporter 352 499 1.1E-31 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS05080 129b1a2601893ca87019b03e0f36e396 900 Gene3D G3DSA:2.60.200.20 238 321 3.4E-22 T 10-11-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 A4G23_RS05080 129b1a2601893ca87019b03e0f36e396 900 Pfam PF01061 ABC-2 type transporter 625 835 7.8E-21 T 10-11-2016 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A4G23_RS05080 129b1a2601893ca87019b03e0f36e396 900 SMART SM00382 361 555 1.8E-13 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS05080 129b1a2601893ca87019b03e0f36e396 900 SMART SM00240 20 70 7.3E-10 T 10-11-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 A4G23_RS05080 129b1a2601893ca87019b03e0f36e396 900 SMART SM00240 246 297 5.4E-14 T 10-11-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 A4G23_RS14805 856ddf9f73fed2e194104c01a2bc5eef 114 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 74 18.885 T 10-11-2016 IPR003482 Transcription factor WhiB A4G23_RS14805 856ddf9f73fed2e194104c01a2bc5eef 114 Pfam PF02467 Transcription factor WhiB 7 69 9.2E-25 T 10-11-2016 IPR003482 Transcription factor WhiB A4G23_RS13490 5bcf7072fd62d4e2155d8c8445648a33 169 SUPERFAMILY SSF82708 123 168 1.29E-11 T 10-11-2016 IPR001374 R3H domain GO:0003676 A4G23_RS13490 5bcf7072fd62d4e2155d8c8445648a33 169 SMART SM00393 91 169 4.7E-28 T 10-11-2016 IPR001374 R3H domain GO:0003676 A4G23_RS13490 5bcf7072fd62d4e2155d8c8445648a33 169 Gene3D G3DSA:3.30.300.120 19 101 7.6E-22 T 10-11-2016 A4G23_RS13490 5bcf7072fd62d4e2155d8c8445648a33 169 Pfam PF01424 R3H domain 111 166 3.6E-15 T 10-11-2016 IPR001374 R3H domain GO:0003676 A4G23_RS13490 5bcf7072fd62d4e2155d8c8445648a33 169 Gene3D G3DSA:3.30.1370.50 102 168 6.1E-24 T 10-11-2016 IPR001374 R3H domain GO:0003676 A4G23_RS02175 2ae3037f3d8b365954114b7d89e94a67 337 Gene3D G3DSA:3.40.50.2300 177 312 4.9E-56 T 10-11-2016 A4G23_RS02175 2ae3037f3d8b365954114b7d89e94a67 337 SUPERFAMILY SSF53822 64 335 9.58E-74 T 10-11-2016 IPR028082 Periplasmic binding protein-like I A4G23_RS02175 2ae3037f3d8b365954114b7d89e94a67 337 Gene3D G3DSA:3.40.50.2300 54 176 2.1E-19 T 10-11-2016 A4G23_RS02175 2ae3037f3d8b365954114b7d89e94a67 337 Pfam PF13377 Periplasmic binding protein-like domain 171 332 1.1E-42 T 10-11-2016 A4G23_RS02175 2ae3037f3d8b365954114b7d89e94a67 337 Pfam PF00356 Bacterial regulatory proteins, lacI family 11 51 1.9E-12 T 10-11-2016 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4G23_RS02175 2ae3037f3d8b365954114b7d89e94a67 337 SUPERFAMILY SSF47413 5 52 5.0E-11 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS02175 2ae3037f3d8b365954114b7d89e94a67 337 SMART SM00354 5 73 3.0E-10 T 10-11-2016 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4G23_RS02175 2ae3037f3d8b365954114b7d89e94a67 337 Gene3D G3DSA:1.10.260.40 5 51 5.8E-16 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS00755 bce8b2f3940d712307165c3953a35b0b 351 SUPERFAMILY SSF56112 22 289 1.89E-72 T 10-11-2016 IPR011009 Protein kinase-like domain A4G23_RS00755 bce8b2f3940d712307165c3953a35b0b 351 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 143 155 - T 10-11-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 A4G23_RS00755 bce8b2f3940d712307165c3953a35b0b 351 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 30 53 - T 10-11-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 A4G23_RS00755 bce8b2f3940d712307165c3953a35b0b 351 Pfam PF00069 Protein kinase domain 24 237 7.2E-45 T 10-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4G23_RS00755 bce8b2f3940d712307165c3953a35b0b 351 Gene3D G3DSA:1.10.510.10 89 278 1.6E-47 T 10-11-2016 A4G23_RS00755 bce8b2f3940d712307165c3953a35b0b 351 Gene3D G3DSA:3.30.200.20 22 88 1.7E-21 T 10-11-2016 A4G23_RS00755 bce8b2f3940d712307165c3953a35b0b 351 SMART SM00220 24 288 4.7E-58 T 10-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4G23_RS06650 b35916fe898a4d1fd4e58f642398db34 368 PRINTS PR00834 HtrA/DegQ protease family signature 205 222 9.0E-34 T 10-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4G23_RS06650 b35916fe898a4d1fd4e58f642398db34 368 PRINTS PR00834 HtrA/DegQ protease family signature 98 110 9.0E-34 T 10-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4G23_RS06650 b35916fe898a4d1fd4e58f642398db34 368 PRINTS PR00834 HtrA/DegQ protease family signature 120 140 9.0E-34 T 10-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4G23_RS06650 b35916fe898a4d1fd4e58f642398db34 368 PRINTS PR00834 HtrA/DegQ protease family signature 314 326 9.0E-34 T 10-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4G23_RS06650 b35916fe898a4d1fd4e58f642398db34 368 PRINTS PR00834 HtrA/DegQ protease family signature 227 244 9.0E-34 T 10-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4G23_RS06650 b35916fe898a4d1fd4e58f642398db34 368 PRINTS PR00834 HtrA/DegQ protease family signature 163 187 9.0E-34 T 10-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4G23_RS06650 b35916fe898a4d1fd4e58f642398db34 368 Gene3D G3DSA:2.40.10.10 164 275 1.9E-35 T 10-11-2016 A4G23_RS06650 b35916fe898a4d1fd4e58f642398db34 368 Gene3D G3DSA:2.40.10.10 83 163 1.4E-23 T 10-11-2016 A4G23_RS06650 b35916fe898a4d1fd4e58f642398db34 368 SMART SM00228 280 356 8.7E-9 T 10-11-2016 IPR001478 PDZ domain GO:0005515 A4G23_RS06650 b35916fe898a4d1fd4e58f642398db34 368 SUPERFAMILY SSF50156 250 357 2.1E-17 T 10-11-2016 IPR001478 PDZ domain GO:0005515 A4G23_RS06650 b35916fe898a4d1fd4e58f642398db34 368 Pfam PF13365 Trypsin-like peptidase domain 89 234 2.1E-28 T 10-11-2016 A4G23_RS06650 b35916fe898a4d1fd4e58f642398db34 368 Gene3D G3DSA:2.30.42.10 279 367 4.0E-20 T 10-11-2016 IPR001478 PDZ domain GO:0005515 A4G23_RS06650 b35916fe898a4d1fd4e58f642398db34 368 Pfam PF13180 PDZ domain 296 365 5.6E-17 T 10-11-2016 IPR001478 PDZ domain GO:0005515 A4G23_RS06650 b35916fe898a4d1fd4e58f642398db34 368 SUPERFAMILY SSF50494 66 272 2.86E-49 T 10-11-2016 IPR009003 Peptidase S1, PA clan A4G23_RS13935 bdb8bd0f3ec59605db5c215571a5245a 138 SUPERFAMILY SSF46785 33 137 1.26E-26 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS13935 bdb8bd0f3ec59605db5c215571a5245a 138 Gene3D G3DSA:1.10.10.10 30 137 2.7E-30 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS13935 bdb8bd0f3ec59605db5c215571a5245a 138 PRINTS PR00598 Bacterial regulatory protein MarR family signature 49 65 5.1E-7 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS13935 bdb8bd0f3ec59605db5c215571a5245a 138 PRINTS PR00598 Bacterial regulatory protein MarR family signature 85 101 5.1E-7 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS13935 bdb8bd0f3ec59605db5c215571a5245a 138 PRINTS PR00598 Bacterial regulatory protein MarR family signature 66 81 5.1E-7 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS13935 bdb8bd0f3ec59605db5c215571a5245a 138 PRINTS PR00598 Bacterial regulatory protein MarR family signature 115 135 5.1E-7 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS13935 bdb8bd0f3ec59605db5c215571a5245a 138 SMART SM00347 25 125 3.2E-14 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS13935 bdb8bd0f3ec59605db5c215571a5245a 138 Pfam PF01047 MarR family 38 89 5.8E-12 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS02800 e5ffc7d5319886221c3d2384cf19dc4b 464 Gene3D G3DSA:3.40.630.30 306 434 1.2E-16 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS02800 e5ffc7d5319886221c3d2384cf19dc4b 464 SUPERFAMILY SSF55729 296 436 9.59E-20 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS02800 e5ffc7d5319886221c3d2384cf19dc4b 464 Pfam PF00583 Acetyltransferase (GNAT) family 369 436 5.1E-6 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS02800 e5ffc7d5319886221c3d2384cf19dc4b 464 SUPERFAMILY SSF55021 114 179 6.34E-5 T 10-11-2016 A4G23_RS02800 e5ffc7d5319886221c3d2384cf19dc4b 464 Gene3D G3DSA:3.30.70.260 116 179 4.5E-4 T 10-11-2016 A4G23_RS08515 09ddf88c4e537cd52dd12d7b171da09e 541 Pfam PF13672 Protein phosphatase 2C 271 489 2.4E-10 T 10-11-2016 A4G23_RS08515 09ddf88c4e537cd52dd12d7b171da09e 541 PRINTS PR01217 Proline rich extensin signature 103 128 5.7E-9 T 10-11-2016 A4G23_RS08515 09ddf88c4e537cd52dd12d7b171da09e 541 PRINTS PR01217 Proline rich extensin signature 33 54 5.7E-9 T 10-11-2016 A4G23_RS08515 09ddf88c4e537cd52dd12d7b171da09e 541 PRINTS PR01217 Proline rich extensin signature 79 96 5.7E-9 T 10-11-2016 A4G23_RS08515 09ddf88c4e537cd52dd12d7b171da09e 541 PRINTS PR01217 Proline rich extensin signature 54 70 5.7E-9 T 10-11-2016 A4G23_RS08515 09ddf88c4e537cd52dd12d7b171da09e 541 SMART SM00331 263 535 6.9E-4 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS08515 09ddf88c4e537cd52dd12d7b171da09e 541 SMART SM00332 254 533 3.2E-6 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS08515 09ddf88c4e537cd52dd12d7b171da09e 541 SUPERFAMILY SSF81606 258 351 2.22E-34 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS08515 09ddf88c4e537cd52dd12d7b171da09e 541 SUPERFAMILY SSF81606 380 537 2.22E-34 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS08515 09ddf88c4e537cd52dd12d7b171da09e 541 Gene3D G3DSA:3.60.40.10 255 535 1.1E-45 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS18305 398485a7c47a1967ab40fde924976709 362 PIRSF PIRSF006641 1 362 6.3E-142 T 10-11-2016 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 A4G23_RS18305 398485a7c47a1967ab40fde924976709 362 Gene3D G3DSA:3.10.20.30 262 362 1.5E-45 T 10-11-2016 IPR012675 Beta-grasp domain A4G23_RS18305 398485a7c47a1967ab40fde924976709 362 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 3 362 3.8E-132 T 10-11-2016 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 A4G23_RS18305 398485a7c47a1967ab40fde924976709 362 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 362 42.338 T 10-11-2016 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 A4G23_RS18305 398485a7c47a1967ab40fde924976709 362 SUPERFAMILY SSF52540 3 300 6.67E-73 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS18305 398485a7c47a1967ab40fde924976709 362 SUPERFAMILY SSF81271 278 362 2.62E-35 T 10-11-2016 IPR012676 TGS-like KEGG: 00970+6.1.1.3 A4G23_RS18305 398485a7c47a1967ab40fde924976709 362 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 3.2E-34 T 10-11-2016 IPR006073 GTP binding domain GO:0005525 A4G23_RS18305 398485a7c47a1967ab40fde924976709 362 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 3.2E-34 T 10-11-2016 IPR006073 GTP binding domain GO:0005525 A4G23_RS18305 398485a7c47a1967ab40fde924976709 362 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 3.2E-34 T 10-11-2016 IPR006073 GTP binding domain GO:0005525 A4G23_RS18305 398485a7c47a1967ab40fde924976709 362 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 3.2E-34 T 10-11-2016 IPR006073 GTP binding domain GO:0005525 A4G23_RS18305 398485a7c47a1967ab40fde924976709 362 Gene3D G3DSA:3.40.50.300 3 131 1.6E-42 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS18305 398485a7c47a1967ab40fde924976709 362 Gene3D G3DSA:3.40.50.300 202 261 1.6E-42 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS18305 398485a7c47a1967ab40fde924976709 362 Pfam PF06071 Protein of unknown function (DUF933) 278 361 3.9E-39 T 10-11-2016 IPR013029 Domain of unknown function DUF933 A4G23_RS18305 398485a7c47a1967ab40fde924976709 362 Gene3D G3DSA:1.10.150.300 132 201 1.4E-18 T 10-11-2016 IPR023192 TGS-like domain A4G23_RS18305 398485a7c47a1967ab40fde924976709 362 Pfam PF01926 50S ribosome-binding GTPase 5 123 1.3E-22 T 10-11-2016 IPR006073 GTP binding domain GO:0005525 A4G23_RS24135 aac1aef1e7e3152c737d0e0bc97127a3 561 Hamap MF_01491 Ribonuclease J [rnj]. 14 561 39.908 T 10-11-2016 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 A4G23_RS24135 aac1aef1e7e3152c737d0e0bc97127a3 561 Pfam PF00753 Metallo-beta-lactamase superfamily 28 174 4.1E-15 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS24135 aac1aef1e7e3152c737d0e0bc97127a3 561 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 20 559 4.9E-149 T 10-11-2016 IPR004613 Ribonuclease J GO:0003723|GO:0046872 A4G23_RS24135 aac1aef1e7e3152c737d0e0bc97127a3 561 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 370 413 5.3E-9 T 10-11-2016 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain A4G23_RS24135 aac1aef1e7e3152c737d0e0bc97127a3 561 PIRSF PIRSF004803 14 561 2.8E-203 T 10-11-2016 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 A4G23_RS24135 aac1aef1e7e3152c737d0e0bc97127a3 561 SMART SM00849 31 225 4.1E-25 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS24135 aac1aef1e7e3152c737d0e0bc97127a3 561 Gene3D G3DSA:3.60.15.10 18 265 3.1E-74 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS24135 aac1aef1e7e3152c737d0e0bc97127a3 561 SUPERFAMILY SSF56281 19 433 3.94E-95 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS23970 ff2866f3ed772b6b26b1a7f766aa61cd 86 SUPERFAMILY SSF47336 8 67 4.32E-12 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS23970 ff2866f3ed772b6b26b1a7f766aa61cd 86 Gene3D G3DSA:1.10.1200.10 10 80 9.4E-14 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS23970 ff2866f3ed772b6b26b1a7f766aa61cd 86 Pfam PF00550 Phosphopantetheine attachment site 16 67 1.1E-8 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS05030 f1a848d4b2a7000116937302df0b3a01 179 Pfam PF01161 Phosphatidylethanolamine-binding protein 40 173 2.9E-38 T 10-11-2016 IPR008914 Phosphatidylethanolamine-binding protein A4G23_RS05030 f1a848d4b2a7000116937302df0b3a01 179 SUPERFAMILY SSF49777 20 175 3.79E-50 T 10-11-2016 IPR008914 Phosphatidylethanolamine-binding protein A4G23_RS05030 f1a848d4b2a7000116937302df0b3a01 179 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 39 170 2.5E-40 T 10-11-2016 IPR005247 YbhB/YbcL A4G23_RS05030 f1a848d4b2a7000116937302df0b3a01 179 Gene3D G3DSA:3.90.280.10 19 175 2.8E-53 T 10-11-2016 IPR008914 Phosphatidylethanolamine-binding protein A4G23_RS01360 5b77c6800d7000f7492c69cc2b7bcb8d 244 Gene3D G3DSA:1.10.530.10 155 239 1.5E-9 T 10-11-2016 A4G23_RS01360 5b77c6800d7000f7492c69cc2b7bcb8d 244 Pfam PF01464 Transglycosylase SLT domain 169 239 1.4E-7 T 10-11-2016 IPR008258 Transglycosylase SLT domain 1 A4G23_RS01360 5b77c6800d7000f7492c69cc2b7bcb8d 244 SUPERFAMILY SSF53955 125 238 9.37E-15 T 10-11-2016 IPR023346 Lysozyme-like domain A4G23_RS01360 5b77c6800d7000f7492c69cc2b7bcb8d 244 Gene3D G3DSA:3.10.350.10 67 116 1.1E-6 T 10-11-2016 IPR018392 LysM domain A4G23_RS01360 5b77c6800d7000f7492c69cc2b7bcb8d 244 Pfam PF01476 LysM domain 69 116 9.3E-5 T 10-11-2016 IPR018392 LysM domain A4G23_RS11960 1f93b5d15403b9a5b4a3d9c88e0c7908 193 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 1 185 21.532 T 10-11-2016 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 A4G23_RS11960 1f93b5d15403b9a5b4a3d9c88e0c7908 193 Gene3D G3DSA:3.90.1140.10 1 186 4.3E-52 T 10-11-2016 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase A4G23_RS11960 1f93b5d15403b9a5b4a3d9c88e0c7908 193 Pfam PF02834 LigT like Phosphoesterase 9 86 7.1E-14 T 10-11-2016 IPR014051 Phosphoesterase, HXTX A4G23_RS11960 1f93b5d15403b9a5b4a3d9c88e0c7908 193 Pfam PF02834 LigT like Phosphoesterase 97 170 7.4E-7 T 10-11-2016 IPR014051 Phosphoesterase, HXTX A4G23_RS11960 1f93b5d15403b9a5b4a3d9c88e0c7908 193 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 1 185 2.6E-30 T 10-11-2016 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 A4G23_RS11960 1f93b5d15403b9a5b4a3d9c88e0c7908 193 SUPERFAMILY SSF55144 1 187 1.57E-36 T 10-11-2016 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase A4G23_RS15175 b6624e5f06d14c5d35216207cfaf0edf 78 SUPERFAMILY SSF143800 2 76 7.65E-25 T 10-11-2016 A4G23_RS15175 b6624e5f06d14c5d35216207cfaf0edf 78 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 71 19.526 T 10-11-2016 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS15175 b6624e5f06d14c5d35216207cfaf0edf 78 TIGRFAM TIGR00009 L28: ribosomal protein bL28 2 58 1.4E-24 T 10-11-2016 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS15175 b6624e5f06d14c5d35216207cfaf0edf 78 Pfam PF00830 Ribosomal L28 family 4 60 3.3E-23 T 10-11-2016 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS15175 b6624e5f06d14c5d35216207cfaf0edf 78 Gene3D G3DSA:2.30.170.40 2 77 2.8E-30 T 10-11-2016 A4G23_RS22075 45283bd7ec9949d1fc3b5ee779d39c52 2148 SMART SM00823 Phosphopantetheine attachment site 1083 1152 7.0E-10 T 10-11-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4G23_RS22075 45283bd7ec9949d1fc3b5ee779d39c52 2148 Gene3D G3DSA:3.40.47.10 1505 1671 3.7E-53 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS22075 45283bd7ec9949d1fc3b5ee779d39c52 2148 Gene3D G3DSA:3.40.47.10 280 441 4.8E-50 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS22075 45283bd7ec9949d1fc3b5ee779d39c52 2148 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1107 1122 - T 10-11-2016 IPR006162 Phosphopantetheine attachment site A4G23_RS22075 45283bd7ec9949d1fc3b5ee779d39c52 2148 SMART SM00826 738 889 0.0041 T 10-11-2016 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4G23_RS22075 45283bd7ec9949d1fc3b5ee779d39c52 2148 Gene3D G3DSA:1.10.1200.10 1096 1151 3.2E-11 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS22075 45283bd7ec9949d1fc3b5ee779d39c52 2148 Pfam PF00698 Acyl transferase domain 1769 2047 1.3E-54 T 10-11-2016 IPR014043 Acyl transferase A4G23_RS22075 45283bd7ec9949d1fc3b5ee779d39c52 2148 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1770 2061 4.3E-87 T 10-11-2016 IPR020801 Polyketide synthase, acyl transferase domain A4G23_RS22075 45283bd7ec9949d1fc3b5ee779d39c52 2148 SUPERFAMILY SSF53901 5 121 4.83E-68 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS22075 45283bd7ec9949d1fc3b5ee779d39c52 2148 SUPERFAMILY SSF53901 416 437 4.83E-68 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS22075 45283bd7ec9949d1fc3b5ee779d39c52 2148 SUPERFAMILY SSF53901 163 386 4.83E-68 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS22075 45283bd7ec9949d1fc3b5ee779d39c52 2148 SMART SM00825 Beta-ketoacyl synthase 8 441 2.0E-109 T 10-11-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4G23_RS22075 45283bd7ec9949d1fc3b5ee779d39c52 2148 SMART SM00825 Beta-ketoacyl synthase 1260 1671 1.4E-139 T 10-11-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4G23_RS22075 45283bd7ec9949d1fc3b5ee779d39c52 2148 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 180 196 - T 10-11-2016 IPR018201 Beta-ketoacyl synthase, active site A4G23_RS22075 45283bd7ec9949d1fc3b5ee779d39c52 2148 Pfam PF00550 Phosphopantetheine attachment site 1094 1148 2.6E-8 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS22075 45283bd7ec9949d1fc3b5ee779d39c52 2148 Gene3D G3DSA:3.40.366.10 1952 2061 8.1E-68 T 10-11-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 A4G23_RS22075 45283bd7ec9949d1fc3b5ee779d39c52 2148 Gene3D G3DSA:3.40.366.10 1766 1888 8.1E-68 T 10-11-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 A4G23_RS22075 45283bd7ec9949d1fc3b5ee779d39c52 2148 Gene3D G3DSA:3.40.47.10 1260 1504 8.5E-67 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS22075 45283bd7ec9949d1fc3b5ee779d39c52 2148 Gene3D G3DSA:3.40.47.10 8 279 9.8E-66 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS22075 45283bd7ec9949d1fc3b5ee779d39c52 2148 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 392 499 1.6E-11 T 10-11-2016 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4G23_RS22075 45283bd7ec9949d1fc3b5ee779d39c52 2148 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1620 1726 5.1E-10 T 10-11-2016 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4G23_RS22075 45283bd7ec9949d1fc3b5ee779d39c52 2148 SUPERFAMILY SSF55048 1892 1942 4.19E-8 T 10-11-2016 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 A4G23_RS22075 45283bd7ec9949d1fc3b5ee779d39c52 2148 SUPERFAMILY SSF47336 1093 1153 2.36E-10 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS22075 45283bd7ec9949d1fc3b5ee779d39c52 2148 Gene3D G3DSA:3.30.70.250 1891 1942 5.6E-7 T 10-11-2016 A4G23_RS22075 45283bd7ec9949d1fc3b5ee779d39c52 2148 SUPERFAMILY SSF52151 1767 1894 1.26E-62 T 10-11-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 A4G23_RS22075 45283bd7ec9949d1fc3b5ee779d39c52 2148 SUPERFAMILY SSF52151 1954 2057 1.26E-62 T 10-11-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 A4G23_RS22075 45283bd7ec9949d1fc3b5ee779d39c52 2148 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 276 387 4.5E-33 T 10-11-2016 IPR014031 Beta-ketoacyl synthase, C-terminal A4G23_RS22075 45283bd7ec9949d1fc3b5ee779d39c52 2148 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1501 1617 9.8E-39 T 10-11-2016 IPR014031 Beta-ketoacyl synthase, C-terminal A4G23_RS22075 45283bd7ec9949d1fc3b5ee779d39c52 2148 SUPERFAMILY SSF53901 1254 1613 3.67E-76 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS22075 45283bd7ec9949d1fc3b5ee779d39c52 2148 SUPERFAMILY SSF53901 1646 1667 3.67E-76 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS22075 45283bd7ec9949d1fc3b5ee779d39c52 2148 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1258 1492 1.3E-57 T 10-11-2016 IPR014030 Beta-ketoacyl synthase, N-terminal A4G23_RS22075 45283bd7ec9949d1fc3b5ee779d39c52 2148 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 6 265 1.1E-60 T 10-11-2016 IPR014030 Beta-ketoacyl synthase, N-terminal A4G23_RS20765 0211262e6bc6107996ff694311c00df1 409 Pfam PF07478 D-ala D-ala ligase C-terminus 127 193 3.0E-5 T 10-11-2016 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4G23_RS20765 0211262e6bc6107996ff694311c00df1 409 SUPERFAMILY SSF56059 110 337 2.75E-23 T 10-11-2016 A4G23_RS20765 0211262e6bc6107996ff694311c00df1 409 Gene3D G3DSA:3.30.1490.20 114 188 4.8E-9 T 10-11-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A4G23_RS07500 2f8e7cde9546f1098b967f22d57beb78 333 Gene3D G3DSA:3.40.47.10 13 170 6.0E-54 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS07500 2f8e7cde9546f1098b967f22d57beb78 333 Gene3D G3DSA:3.40.47.10 171 330 7.9E-47 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS07500 2f8e7cde9546f1098b967f22d57beb78 333 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 11 332 59.729 T 10-11-2016 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A4G23_RS07500 2f8e7cde9546f1098b967f22d57beb78 333 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 12 331 8.1E-108 T 10-11-2016 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A4G23_RS07500 2f8e7cde9546f1098b967f22d57beb78 333 SUPERFAMILY SSF53901 10 331 3.13E-60 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS07500 2f8e7cde9546f1098b967f22d57beb78 333 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 242 331 7.4E-31 T 10-11-2016 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A4G23_RS07500 2f8e7cde9546f1098b967f22d57beb78 333 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 116 193 1.5E-25 T 10-11-2016 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A4G23_RS19980 e4c19119f9123dd42779d2744191245e 556 SUPERFAMILY SSF53850 40 555 4.21E-104 T 10-11-2016 A4G23_RS19980 e4c19119f9123dd42779d2744191245e 556 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 83 480 3.7E-75 T 10-11-2016 IPR000914 Solute-binding protein family 5 domain A4G23_RS19980 e4c19119f9123dd42779d2744191245e 556 Gene3D G3DSA:3.10.105.10 330 524 1.1E-41 T 10-11-2016 A4G23_RS19980 e4c19119f9123dd42779d2744191245e 556 Gene3D G3DSA:3.40.190.10 164 329 4.7E-36 T 10-11-2016 A4G23_RS19980 e4c19119f9123dd42779d2744191245e 556 PIRSF PIRSF002741 1 556 9.0E-81 T 10-11-2016 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A4G23_RS02050 095da2b06f05210adea2c8023c338be2 325 SUPERFAMILY SSF51569 15 317 1.88E-36 T 10-11-2016 A4G23_RS02050 095da2b06f05210adea2c8023c338be2 325 Pfam PF00701 Dihydrodipicolinate synthetase family 14 300 2.4E-15 T 10-11-2016 IPR002220 DapA-like GO:0008152|GO:0016829 A4G23_RS02050 095da2b06f05210adea2c8023c338be2 325 SMART SM01130 11 318 6.2E-16 T 10-11-2016 IPR002220 DapA-like GO:0008152|GO:0016829 A4G23_RS02050 095da2b06f05210adea2c8023c338be2 325 Gene3D G3DSA:3.20.20.70 15 318 1.3E-50 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS04950 3f9f2acb45b9331189e31dd0c252c242 293 Pfam PF01513 ATP-NAD kinase 50 267 1.7E-56 T 10-11-2016 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 A4G23_RS04950 3f9f2acb45b9331189e31dd0c252c242 293 SUPERFAMILY SSF111331 1 289 2.62E-77 T 10-11-2016 IPR016064 NAD kinase/diacylglycerol kinase-like domain A4G23_RS04950 3f9f2acb45b9331189e31dd0c252c242 293 Gene3D G3DSA:2.60.200.30 147 257 2.2E-36 T 10-11-2016 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 A4G23_RS04950 3f9f2acb45b9331189e31dd0c252c242 293 Hamap MF_00361 NAD kinase [nadK]. 2 283 28.206 T 10-11-2016 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 A4G23_RS04950 3f9f2acb45b9331189e31dd0c252c242 293 Gene3D G3DSA:3.40.50.10330 1 146 6.7E-32 T 10-11-2016 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 A4G23_RS03425 c8dfc1a3d8b44c051c2618485024e886 151 Pfam PF01037 Lrp/AsnC ligand binding domain 71 139 8.4E-14 T 10-11-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A4G23_RS03425 c8dfc1a3d8b44c051c2618485024e886 151 ProSitePatterns PS00519 AsnC-type HTH domain signature. 21 47 - T 10-11-2016 IPR019885 Transcription regulator HTH, AsnC-type, conserved site A4G23_RS03425 c8dfc1a3d8b44c051c2618485024e886 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 5.4E-10 T 10-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 A4G23_RS03425 c8dfc1a3d8b44c051c2618485024e886 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 5.4E-10 T 10-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 A4G23_RS03425 c8dfc1a3d8b44c051c2618485024e886 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 5.4E-10 T 10-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 A4G23_RS03425 c8dfc1a3d8b44c051c2618485024e886 151 Gene3D G3DSA:1.10.10.10 5 55 1.5E-18 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS03425 c8dfc1a3d8b44c051c2618485024e886 151 SMART SM00344 3 110 5.4E-27 T 10-11-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A4G23_RS03425 c8dfc1a3d8b44c051c2618485024e886 151 SUPERFAMILY SSF54909 65 143 2.68E-12 T 10-11-2016 IPR011008 Dimeric alpha-beta barrel A4G23_RS03425 c8dfc1a3d8b44c051c2618485024e886 151 SUPERFAMILY SSF46785 2 63 5.37E-15 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS03425 c8dfc1a3d8b44c051c2618485024e886 151 Gene3D G3DSA:3.30.70.920 56 135 1.4E-18 T 10-11-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A4G23_RS03425 c8dfc1a3d8b44c051c2618485024e886 151 Pfam PF13404 AsnC-type helix-turn-helix domain 3 44 1.0E-15 T 10-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 A4G23_RS03510 56d287f84ee5ece83fe455e87c310591 402 PIRSF PIRSF000497 1 401 5.6E-163 T 10-11-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A4G23_RS03510 56d287f84ee5ece83fe455e87c310591 402 Gene3D G3DSA:3.30.300.10 146 250 2.7E-38 T 10-11-2016 A4G23_RS03510 56d287f84ee5ece83fe455e87c310591 402 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 276 284 - T 10-11-2016 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A4G23_RS03510 56d287f84ee5ece83fe455e87c310591 402 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 4 101 1.5E-40 T 10-11-2016 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A4G23_RS03510 56d287f84ee5ece83fe455e87c310591 402 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 2 400 56.772 T 10-11-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A4G23_RS03510 56d287f84ee5ece83fe455e87c310591 402 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 5 399 2.5E-169 T 10-11-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A4G23_RS03510 56d287f84ee5ece83fe455e87c310591 402 SUPERFAMILY SSF55973 3 109 1.96E-44 T 10-11-2016 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A4G23_RS03510 56d287f84ee5ece83fe455e87c310591 402 Gene3D G3DSA:3.30.300.10 261 400 2.5E-69 T 10-11-2016 A4G23_RS03510 56d287f84ee5ece83fe455e87c310591 402 Pfam PF02772 S-adenosylmethionine synthetase, central domain 124 248 8.1E-44 T 10-11-2016 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A4G23_RS03510 56d287f84ee5ece83fe455e87c310591 402 SUPERFAMILY SSF55973 250 401 3.06E-67 T 10-11-2016 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A4G23_RS03510 56d287f84ee5ece83fe455e87c310591 402 SUPERFAMILY SSF55973 120 248 3.49E-45 T 10-11-2016 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A4G23_RS03510 56d287f84ee5ece83fe455e87c310591 402 Gene3D G3DSA:3.30.300.10 11 145 3.5E-45 T 10-11-2016 A4G23_RS03510 56d287f84ee5ece83fe455e87c310591 402 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 250 389 1.3E-67 T 10-11-2016 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A4G23_RS03510 56d287f84ee5ece83fe455e87c310591 402 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 126 136 - T 10-11-2016 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A4G23_RS22070 42c97c13ae3fd0c1c995597ee06b34da 3208 SUPERFAMILY SSF47336 1841 1929 3.14E-10 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS22070 42c97c13ae3fd0c1c995597ee06b34da 3208 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1991 2226 4.4E-69 T 10-11-2016 IPR014030 Beta-ketoacyl synthase, N-terminal A4G23_RS22070 42c97c13ae3fd0c1c995597ee06b34da 3208 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 968 1209 2.4E-62 T 10-11-2016 IPR014030 Beta-ketoacyl synthase, N-terminal A4G23_RS22070 42c97c13ae3fd0c1c995597ee06b34da 3208 SMART SM00825 Beta-ketoacyl synthase 969 1386 1.4E-150 T 10-11-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4G23_RS22070 42c97c13ae3fd0c1c995597ee06b34da 3208 SMART SM00825 Beta-ketoacyl synthase 1993 2406 8.2E-171 T 10-11-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4G23_RS22070 42c97c13ae3fd0c1c995597ee06b34da 3208 Gene3D G3DSA:3.40.47.10 2240 2406 2.6E-55 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS22070 42c97c13ae3fd0c1c995597ee06b34da 3208 Gene3D G3DSA:3.40.47.10 1222 1384 2.3E-58 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS22070 42c97c13ae3fd0c1c995597ee06b34da 3208 Gene3D G3DSA:1.10.1200.10 1836 1916 4.3E-11 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS22070 42c97c13ae3fd0c1c995597ee06b34da 3208 SUPERFAMILY SSF53901 1989 2348 4.36E-82 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS22070 42c97c13ae3fd0c1c995597ee06b34da 3208 SUPERFAMILY SSF53901 2381 2402 4.36E-82 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS22070 42c97c13ae3fd0c1c995597ee06b34da 3208 Pfam PF14765 Polyketide synthase dehydratase 8 266 4.1E-42 T 10-11-2016 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4G23_RS22070 42c97c13ae3fd0c1c995597ee06b34da 3208 Pfam PF14765 Polyketide synthase dehydratase 1637 1802 1.7E-16 T 10-11-2016 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4G23_RS22070 42c97c13ae3fd0c1c995597ee06b34da 3208 SUPERFAMILY SSF51735 540 760 2.7E-35 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS22070 42c97c13ae3fd0c1c995597ee06b34da 3208 ProSitePatterns PS00012 Phosphopantetheine attachment site. 843 858 - T 10-11-2016 IPR006162 Phosphopantetheine attachment site A4G23_RS22070 42c97c13ae3fd0c1c995597ee06b34da 3208 Pfam PF00550 Phosphopantetheine attachment site 821 883 1.6E-7 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS22070 42c97c13ae3fd0c1c995597ee06b34da 3208 Pfam PF00550 Phosphopantetheine attachment site 1848 1911 2.8E-8 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS22070 42c97c13ae3fd0c1c995597ee06b34da 3208 Pfam PF00550 Phosphopantetheine attachment site 3085 3145 1.0E-7 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS22070 42c97c13ae3fd0c1c995597ee06b34da 3208 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3105 3120 - T 10-11-2016 IPR006162 Phosphopantetheine attachment site A4G23_RS22070 42c97c13ae3fd0c1c995597ee06b34da 3208 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2801 2983 1.5E-18 T 10-11-2016 A4G23_RS22070 42c97c13ae3fd0c1c995597ee06b34da 3208 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 543 719 2.8E-34 T 10-11-2016 A4G23_RS22070 42c97c13ae3fd0c1c995597ee06b34da 3208 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1337 1458 1.7E-12 T 10-11-2016 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4G23_RS22070 42c97c13ae3fd0c1c995597ee06b34da 3208 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2355 2461 3.9E-11 T 10-11-2016 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4G23_RS22070 42c97c13ae3fd0c1c995597ee06b34da 3208 Gene3D G3DSA:1.10.1200.10 3082 3139 6.3E-9 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS22070 42c97c13ae3fd0c1c995597ee06b34da 3208 Gene3D G3DSA:1.10.1200.10 816 888 2.9E-12 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS22070 42c97c13ae3fd0c1c995597ee06b34da 3208 Gene3D G3DSA:3.40.47.10 969 1221 1.5E-72 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS22070 42c97c13ae3fd0c1c995597ee06b34da 3208 Gene3D G3DSA:3.40.47.10 1993 2239 3.9E-81 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS22070 42c97c13ae3fd0c1c995597ee06b34da 3208 SUPERFAMILY SSF51735 308 520 3.12E-27 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS22070 42c97c13ae3fd0c1c995597ee06b34da 3208 SMART SM00826 1 150 7.5E-6 T 10-11-2016 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4G23_RS22070 42c97c13ae3fd0c1c995597ee06b34da 3208 SUPERFAMILY SSF47336 3079 3167 3.14E-11 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS22070 42c97c13ae3fd0c1c995597ee06b34da 3208 Pfam PF08659 KR domain 2801 2981 7.7E-37 T 10-11-2016 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4G23_RS22070 42c97c13ae3fd0c1c995597ee06b34da 3208 Pfam PF08659 KR domain 543 717 1.7E-46 T 10-11-2016 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4G23_RS22070 42c97c13ae3fd0c1c995597ee06b34da 3208 Gene3D G3DSA:3.40.50.720 3140 3151 4.0E-31 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS22070 42c97c13ae3fd0c1c995597ee06b34da 3208 Gene3D G3DSA:3.40.50.720 542 751 3.9E-35 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS22070 42c97c13ae3fd0c1c995597ee06b34da 3208 Gene3D G3DSA:3.40.50.720 2801 2986 4.0E-31 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS22070 42c97c13ae3fd0c1c995597ee06b34da 3208 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1870 1885 - T 10-11-2016 IPR006162 Phosphopantetheine attachment site A4G23_RS22070 42c97c13ae3fd0c1c995597ee06b34da 3208 SUPERFAMILY SSF51735 2799 3037 2.1E-30 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS22070 42c97c13ae3fd0c1c995597ee06b34da 3208 SMART SM00823 Phosphopantetheine attachment site 819 888 3.4E-11 T 10-11-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4G23_RS22070 42c97c13ae3fd0c1c995597ee06b34da 3208 SMART SM00823 Phosphopantetheine attachment site 3079 3150 1.8E-4 T 10-11-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4G23_RS22070 42c97c13ae3fd0c1c995597ee06b34da 3208 SMART SM00823 Phosphopantetheine attachment site 1843 1915 8.6E-4 T 10-11-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4G23_RS22070 42c97c13ae3fd0c1c995597ee06b34da 3208 SUPERFAMILY SSF47336 816 896 5.37E-12 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS22070 42c97c13ae3fd0c1c995597ee06b34da 3208 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1218 1334 1.7E-37 T 10-11-2016 IPR014031 Beta-ketoacyl synthase, C-terminal A4G23_RS22070 42c97c13ae3fd0c1c995597ee06b34da 3208 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2236 2352 2.0E-38 T 10-11-2016 IPR014031 Beta-ketoacyl synthase, C-terminal A4G23_RS22070 42c97c13ae3fd0c1c995597ee06b34da 3208 SUPERFAMILY SSF53901 966 1330 9.02E-79 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS22070 42c97c13ae3fd0c1c995597ee06b34da 3208 SUPERFAMILY SSF53901 1361 1382 9.02E-79 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS22275 36ea44538341a7de26eb9588f0519cc4 377 PIRSF PIRSF006404 1 377 4.6E-91 T 10-11-2016 IPR016483 Uncharacterised conserved protein UCP006404, peptidase M50/CBS A4G23_RS22275 36ea44538341a7de26eb9588f0519cc4 377 Pfam PF02163 Peptidase family M50 142 186 6.8E-8 T 10-11-2016 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033 A4G23_RS22275 36ea44538341a7de26eb9588f0519cc4 377 Pfam PF00571 CBS domain 248 303 0.0067 T 10-11-2016 IPR000644 CBS domain A4G23_RS22275 36ea44538341a7de26eb9588f0519cc4 377 Pfam PF00571 CBS domain 329 373 1.9E-5 T 10-11-2016 IPR000644 CBS domain A4G23_RS22275 36ea44538341a7de26eb9588f0519cc4 377 SUPERFAMILY SSF54631 246 374 2.24E-15 T 10-11-2016 A4G23_RS22275 36ea44538341a7de26eb9588f0519cc4 377 Gene3D G3DSA:3.10.580.10 248 374 2.3E-12 T 10-11-2016 A4G23_RS00710 3a5b94f21bc93fda08adc3abe7ccc088 690 SUPERFAMILY SSF55785 28 132 5.93E-12 T 10-11-2016 IPR000014 PAS domain A4G23_RS00710 3a5b94f21bc93fda08adc3abe7ccc088 690 Gene3D G3DSA:3.30.450.20 29 131 1.3E-14 T 10-11-2016 A4G23_RS00710 3a5b94f21bc93fda08adc3abe7ccc088 690 Pfam PF08447 PAS fold 40 128 1.0E-9 T 10-11-2016 IPR013655 PAS fold-3 GO:0005515 A4G23_RS00710 3a5b94f21bc93fda08adc3abe7ccc088 690 SMART SM00065 163 317 0.0034 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS00710 3a5b94f21bc93fda08adc3abe7ccc088 690 SUPERFAMILY SSF55781 183 320 2.4E-13 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS00710 3a5b94f21bc93fda08adc3abe7ccc088 690 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 364 552 2.3E-45 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS00710 3a5b94f21bc93fda08adc3abe7ccc088 690 Gene3D G3DSA:3.30.450.40 145 320 2.5E-13 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS00710 3a5b94f21bc93fda08adc3abe7ccc088 690 Pfam PF13185 GAF domain 182 307 1.0E-7 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS00710 3a5b94f21bc93fda08adc3abe7ccc088 690 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 68 139 1.0E-7 T 10-11-2016 IPR000014 PAS domain A4G23_RS00710 3a5b94f21bc93fda08adc3abe7ccc088 690 SUPERFAMILY SSF81606 344 551 6.15E-9 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS00710 3a5b94f21bc93fda08adc3abe7ccc088 690 SMART SM00331 335 552 1.0E-33 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS03740 0641ec01b9857ead93b6c313b2024325 197 ProSitePatterns PS01236 PdxT/SNO family family signature. 43 53 - T 10-11-2016 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A4G23_RS03740 0641ec01b9857ead93b6c313b2024325 197 SUPERFAMILY SSF52317 5 193 1.44E-51 T 10-11-2016 IPR029062 Class I glutamine amidotransferase-like A4G23_RS03740 0641ec01b9857ead93b6c313b2024325 197 PIRSF PIRSF005639 1 196 8.3E-73 T 10-11-2016 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A4G23_RS03740 0641ec01b9857ead93b6c313b2024325 197 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 6 191 37.158 T 10-11-2016 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A4G23_RS03740 0641ec01b9857ead93b6c313b2024325 197 Gene3D G3DSA:3.40.50.880 2 195 1.5E-76 T 10-11-2016 IPR029062 Class I glutamine amidotransferase-like A4G23_RS03740 0641ec01b9857ead93b6c313b2024325 197 Pfam PF01174 SNO glutamine amidotransferase family 8 192 3.3E-58 T 10-11-2016 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A4G23_RS03740 0641ec01b9857ead93b6c313b2024325 197 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 6 190 1.3E-80 T 10-11-2016 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A4G23_RS19245 efd7ce075618b9bb53c05c78e1b4d89f 809 Gene3D G3DSA:1.10.8.60 510 593 4.0E-27 T 10-11-2016 A4G23_RS19245 efd7ce075618b9bb53c05c78e1b4d89f 809 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 9 199 1.5E-15 T 10-11-2016 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 A4G23_RS19245 efd7ce075618b9bb53c05c78e1b4d89f 809 PIRSF PIRSF001174 1 793 4.9E-240 T 10-11-2016 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 A4G23_RS19245 efd7ce075618b9bb53c05c78e1b4d89f 809 SUPERFAMILY SSF88697 9 199 1.42E-20 T 10-11-2016 IPR015947 PUA-like domain A4G23_RS19245 efd7ce075618b9bb53c05c78e1b4d89f 809 Gene3D G3DSA:3.30.230.10 605 789 5.2E-68 T 10-11-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A4G23_RS19245 efd7ce075618b9bb53c05c78e1b4d89f 809 SUPERFAMILY SSF52540 307 586 8.62E-49 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS19245 efd7ce075618b9bb53c05c78e1b4d89f 809 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 694 702 - T 10-11-2016 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 A4G23_RS19245 efd7ce075618b9bb53c05c78e1b4d89f 809 Gene3D G3DSA:3.40.50.300 307 509 6.0E-33 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS19245 efd7ce075618b9bb53c05c78e1b4d89f 809 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 362 497 7.7E-20 T 10-11-2016 IPR003959 ATPase, AAA-type, core GO:0005524 A4G23_RS19245 efd7ce075618b9bb53c05c78e1b4d89f 809 SUPERFAMILY SSF54211 610 788 2.54E-51 T 10-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold A4G23_RS19245 efd7ce075618b9bb53c05c78e1b4d89f 809 TIGRFAM TIGR00763 lon: endopeptidase La 11 789 4.3E-235 T 10-11-2016 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 A4G23_RS19245 efd7ce075618b9bb53c05c78e1b4d89f 809 SMART SM00382 357 501 4.6E-10 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS19245 efd7ce075618b9bb53c05c78e1b4d89f 809 SMART SM00464 9 200 4.8E-20 T 10-11-2016 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 A4G23_RS19245 efd7ce075618b9bb53c05c78e1b4d89f 809 Hamap MF_01973 Lon protease [lon]. 10 790 58.034 T 10-11-2016 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 A4G23_RS19245 efd7ce075618b9bb53c05c78e1b4d89f 809 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 580 790 2.6E-76 T 10-11-2016 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 A4G23_RS19245 efd7ce075618b9bb53c05c78e1b4d89f 809 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 691 710 3.6E-50 T 10-11-2016 A4G23_RS19245 efd7ce075618b9bb53c05c78e1b4d89f 809 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 365 384 3.6E-50 T 10-11-2016 A4G23_RS19245 efd7ce075618b9bb53c05c78e1b4d89f 809 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 721 740 3.6E-50 T 10-11-2016 A4G23_RS19245 efd7ce075618b9bb53c05c78e1b4d89f 809 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 744 762 3.6E-50 T 10-11-2016 A4G23_RS19245 efd7ce075618b9bb53c05c78e1b4d89f 809 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 610 626 3.6E-50 T 10-11-2016 A4G23_RS02010 e7d1991dfacddaad0ccab80ddaaee3fa 225 SMART SM00986 53 212 4.3E-29 T 10-11-2016 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4G23_RS02010 e7d1991dfacddaad0ccab80ddaaee3fa 225 SMART SM00987 53 212 4.3E-29 T 10-11-2016 A4G23_RS02010 e7d1991dfacddaad0ccab80ddaaee3fa 225 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 61 70 - T 10-11-2016 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4G23_RS02010 e7d1991dfacddaad0ccab80ddaaee3fa 225 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 11 223 33.447 T 10-11-2016 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4G23_RS02010 e7d1991dfacddaad0ccab80ddaaee3fa 225 Gene3D G3DSA:3.40.470.10 6 224 1.1E-78 T 10-11-2016 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4G23_RS02010 e7d1991dfacddaad0ccab80ddaaee3fa 225 SUPERFAMILY SSF52141 9 224 2.16E-70 T 10-11-2016 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4G23_RS02010 e7d1991dfacddaad0ccab80ddaaee3fa 225 Pfam PF03167 Uracil DNA glycosylase superfamily 55 210 1.3E-16 T 10-11-2016 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4G23_RS09890 c07ffeec5aee557e83752c87cd75ca9b 330 Gene3D G3DSA:1.10.8.300 215 323 2.3E-39 T 10-11-2016 A4G23_RS09890 c07ffeec5aee557e83752c87cd75ca9b 330 Gene3D G3DSA:3.40.50.300 31 195 3.0E-43 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS09890 c07ffeec5aee557e83752c87cd75ca9b 330 PIRSF PIRSF002849 1 328 2.6E-134 T 10-11-2016 IPR016366 ATPase chaperone, AAA-type, MoxR, predicted A4G23_RS09890 c07ffeec5aee557e83752c87cd75ca9b 330 SUPERFAMILY SSF52540 17 302 1.64E-48 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS09890 c07ffeec5aee557e83752c87cd75ca9b 330 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 49 179 4.1E-65 T 10-11-2016 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 A4G23_RS18405 7597189008198d8d032455bb568ddd5f 635 Pfam PF00679 Elongation factor G C-terminus 425 504 5.2E-20 T 10-11-2016 IPR000640 Translation elongation factor EFG, V domain A4G23_RS18405 7597189008198d8d032455bb568ddd5f 635 PRINTS PR00315 GTP-binding elongation factor signature 81 91 4.8E-16 T 10-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4G23_RS18405 7597189008198d8d032455bb568ddd5f 635 PRINTS PR00315 GTP-binding elongation factor signature 133 142 4.8E-16 T 10-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4G23_RS18405 7597189008198d8d032455bb568ddd5f 635 PRINTS PR00315 GTP-binding elongation factor signature 55 63 4.8E-16 T 10-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4G23_RS18405 7597189008198d8d032455bb568ddd5f 635 PRINTS PR00315 GTP-binding elongation factor signature 97 108 4.8E-16 T 10-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4G23_RS18405 7597189008198d8d032455bb568ddd5f 635 PRINTS PR00315 GTP-binding elongation factor signature 9 22 4.8E-16 T 10-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4G23_RS18405 7597189008198d8d032455bb568ddd5f 635 Gene3D G3DSA:2.40.30.10 222 319 1.9E-30 T 10-11-2016 A4G23_RS18405 7597189008198d8d032455bb568ddd5f 635 SUPERFAMILY SSF52540 4 221 6.04E-50 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS18405 7597189008198d8d032455bb568ddd5f 635 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 7 627 4.2E-289 T 10-11-2016 IPR006298 GTP-binding protein TypA GO:0005525 A4G23_RS18405 7597189008198d8d032455bb568ddd5f 635 SUPERFAMILY SSF54980 319 416 2.81E-9 T 10-11-2016 IPR009022 Elongation factor G, III-V domain A4G23_RS18405 7597189008198d8d032455bb568ddd5f 635 Gene3D G3DSA:3.30.70.240 431 508 3.3E-30 T 10-11-2016 IPR000640 Translation elongation factor EFG, V domain A4G23_RS18405 7597189008198d8d032455bb568ddd5f 635 SUPERFAMILY SSF50447 216 315 1.77E-30 T 10-11-2016 IPR009000 Translation protein, beta-barrel domain A4G23_RS18405 7597189008198d8d032455bb568ddd5f 635 SUPERFAMILY SSF50447 162 184 1.77E-30 T 10-11-2016 IPR009000 Translation protein, beta-barrel domain A4G23_RS18405 7597189008198d8d032455bb568ddd5f 635 Pfam PF03144 Elongation factor Tu domain 2 235 305 8.0E-11 T 10-11-2016 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A4G23_RS18405 7597189008198d8d032455bb568ddd5f 635 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 48 63 - T 10-11-2016 IPR031157 Tr-type G domain, conserved site A4G23_RS18405 7597189008198d8d032455bb568ddd5f 635 Gene3D G3DSA:3.30.70.870 320 430 1.2E-34 T 10-11-2016 A4G23_RS18405 7597189008198d8d032455bb568ddd5f 635 SUPERFAMILY SSF54980 427 541 7.67E-27 T 10-11-2016 IPR009022 Elongation factor G, III-V domain A4G23_RS18405 7597189008198d8d032455bb568ddd5f 635 Pfam PF00009 Elongation factor Tu GTP binding domain 6 211 6.1E-52 T 10-11-2016 A4G23_RS18405 7597189008198d8d032455bb568ddd5f 635 Gene3D G3DSA:2.40.50.250 511 605 4.2E-39 T 10-11-2016 A4G23_RS18405 7597189008198d8d032455bb568ddd5f 635 Gene3D G3DSA:3.40.50.300 3 221 3.1E-56 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS18405 7597189008198d8d032455bb568ddd5f 635 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 7 159 5.0E-22 T 10-11-2016 IPR005225 Small GTP-binding protein domain GO:0005525 A4G23_RS21375 8d744d042abd1b0495dca41c2646172d 614 Gene3D G3DSA:3.40.50.300 4 219 9.4E-43 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS21375 8d744d042abd1b0495dca41c2646172d 614 Pfam PF00005 ABC transporter 20 156 7.9E-20 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS21375 8d744d042abd1b0495dca41c2646172d 614 SUPERFAMILY SSF52540 6 217 2.47E-40 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS21375 8d744d042abd1b0495dca41c2646172d 614 SMART SM00382 28 205 1.7E-8 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS19780 e22c06076f39b5f28f9eb24ec65621d1 400 PRINTS PR00471 Acetate kinase family signature 379 391 8.1E-45 T 10-11-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A4G23_RS19780 e22c06076f39b5f28f9eb24ec65621d1 400 PRINTS PR00471 Acetate kinase family signature 7 18 8.1E-45 T 10-11-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A4G23_RS19780 e22c06076f39b5f28f9eb24ec65621d1 400 PRINTS PR00471 Acetate kinase family signature 206 227 8.1E-45 T 10-11-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A4G23_RS19780 e22c06076f39b5f28f9eb24ec65621d1 400 PRINTS PR00471 Acetate kinase family signature 324 340 8.1E-45 T 10-11-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A4G23_RS19780 e22c06076f39b5f28f9eb24ec65621d1 400 PRINTS PR00471 Acetate kinase family signature 302 315 8.1E-45 T 10-11-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A4G23_RS19780 e22c06076f39b5f28f9eb24ec65621d1 400 PRINTS PR00471 Acetate kinase family signature 176 189 8.1E-45 T 10-11-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A4G23_RS19780 e22c06076f39b5f28f9eb24ec65621d1 400 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 7 18 - T 10-11-2016 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A4G23_RS19780 e22c06076f39b5f28f9eb24ec65621d1 400 SUPERFAMILY SSF53067 6 198 1.36E-63 T 10-11-2016 A4G23_RS19780 e22c06076f39b5f28f9eb24ec65621d1 400 TIGRFAM TIGR00016 ackA: acetate kinase 4 398 1.1E-143 T 10-11-2016 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A4G23_RS19780 e22c06076f39b5f28f9eb24ec65621d1 400 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 206 223 - T 10-11-2016 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A4G23_RS19780 e22c06076f39b5f28f9eb24ec65621d1 400 Hamap MF_00020 Acetate kinase [ackA]. 1 400 179.153 T 10-11-2016 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A4G23_RS19780 e22c06076f39b5f28f9eb24ec65621d1 400 SUPERFAMILY SSF53067 159 399 8.42E-86 T 10-11-2016 A4G23_RS19780 e22c06076f39b5f28f9eb24ec65621d1 400 Gene3D G3DSA:3.30.420.40 6 207 1.3E-11 T 10-11-2016 A4G23_RS19780 e22c06076f39b5f28f9eb24ec65621d1 400 PIRSF PIRSF000722 3 400 5.5E-145 T 10-11-2016 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A4G23_RS19780 e22c06076f39b5f28f9eb24ec65621d1 400 Gene3D G3DSA:3.30.420.40 208 397 1.8E-79 T 10-11-2016 A4G23_RS19780 e22c06076f39b5f28f9eb24ec65621d1 400 Pfam PF00871 Acetokinase family 7 392 2.8E-150 T 10-11-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A4G23_RS11020 db0ea99014e0f4aea5ca9c9eaf087464 246 SMART SM00345 14 73 7.7E-18 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS11020 db0ea99014e0f4aea5ca9c9eaf087464 246 SMART SM00866 97 238 2.1E-15 T 10-11-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A4G23_RS11020 db0ea99014e0f4aea5ca9c9eaf087464 246 Pfam PF07702 UTRA domain 105 236 1.8E-20 T 10-11-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A4G23_RS11020 db0ea99014e0f4aea5ca9c9eaf087464 246 Gene3D G3DSA:3.40.1410.10 74 240 1.6E-31 T 10-11-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain A4G23_RS11020 db0ea99014e0f4aea5ca9c9eaf087464 246 Gene3D G3DSA:1.10.10.10 4 73 2.9E-25 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS11020 db0ea99014e0f4aea5ca9c9eaf087464 246 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 8.2E-7 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS11020 db0ea99014e0f4aea5ca9c9eaf087464 246 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 8.2E-7 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS11020 db0ea99014e0f4aea5ca9c9eaf087464 246 SUPERFAMILY SSF46785 1 84 4.68E-22 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS11020 db0ea99014e0f4aea5ca9c9eaf087464 246 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 73 3.7E-18 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS11020 db0ea99014e0f4aea5ca9c9eaf087464 246 SUPERFAMILY SSF64288 61 240 2.67E-30 T 10-11-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain A4G23_RS11390 d9b1435e60c242cb1b8ab8e2f8d23e7d 215 SUPERFAMILY SSF48498 99 202 1.1E-9 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS11390 d9b1435e60c242cb1b8ab8e2f8d23e7d 215 SUPERFAMILY SSF46689 15 76 1.84E-11 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS11390 d9b1435e60c242cb1b8ab8e2f8d23e7d 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 62 8.6E-6 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS11390 d9b1435e60c242cb1b8ab8e2f8d23e7d 215 Gene3D G3DSA:1.10.357.10 12 192 1.8E-24 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS13560 37ce6aa55e2f5be226a31e8251df4c18 360 TIGRFAM TIGR03450 mycothiol_INO1: inositol 1-phosphate synthase 4 354 1.3E-221 T 10-11-2016 IPR017815 Myo-inositol 1-phosphate synthase, actinobacteria A4G23_RS13560 37ce6aa55e2f5be226a31e8251df4c18 360 PIRSF PIRSF015578 1 360 1.4E-92 T 10-11-2016 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 A4G23_RS13560 37ce6aa55e2f5be226a31e8251df4c18 360 Gene3D G3DSA:3.40.50.720 301 355 3.7E-115 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS13560 37ce6aa55e2f5be226a31e8251df4c18 360 Gene3D G3DSA:3.40.50.720 1 189 3.7E-115 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS13560 37ce6aa55e2f5be226a31e8251df4c18 360 Gene3D G3DSA:3.30.360.10 190 300 2.0E-47 T 10-11-2016 A4G23_RS13560 37ce6aa55e2f5be226a31e8251df4c18 360 Pfam PF01658 Myo-inositol-1-phosphate synthase 191 300 8.5E-32 T 10-11-2016 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 A4G23_RS13560 37ce6aa55e2f5be226a31e8251df4c18 360 SUPERFAMILY SSF51735 3 185 2.84E-92 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS13560 37ce6aa55e2f5be226a31e8251df4c18 360 SUPERFAMILY SSF51735 297 356 2.84E-92 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS13560 37ce6aa55e2f5be226a31e8251df4c18 360 SUPERFAMILY SSF55347 190 299 5.36E-34 T 10-11-2016 A4G23_RS14510 d91bc6acbed695b832dd9bcb11b72646 340 TIGRFAM TIGR01520 FruBisAldo_II_A: fructose-bisphosphate aldolase, class II 3 336 1.7E-127 T 10-11-2016 IPR006411 Fructose-bisphosphate aldolase, class II, yeast/E. coli subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 A4G23_RS14510 d91bc6acbed695b832dd9bcb11b72646 340 SUPERFAMILY SSF51569 4 337 1.9E-95 T 10-11-2016 A4G23_RS14510 d91bc6acbed695b832dd9bcb11b72646 340 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 86 97 - T 10-11-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A4G23_RS14510 d91bc6acbed695b832dd9bcb11b72646 340 Pfam PF01116 Fructose-bisphosphate aldolase class-II 9 336 3.5E-78 T 10-11-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A4G23_RS14510 d91bc6acbed695b832dd9bcb11b72646 340 PIRSF PIRSF001359 5 338 1.2E-62 T 10-11-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A4G23_RS14510 d91bc6acbed695b832dd9bcb11b72646 340 Gene3D G3DSA:3.20.20.70 2 337 2.7E-115 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS14510 d91bc6acbed695b832dd9bcb11b72646 340 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 9 337 2.9E-71 T 10-11-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A4G23_RS26300 713d2caafad5c04191b5bb635c794043 399 Gene3D G3DSA:1.10.630.10 2 398 4.0E-105 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS26300 713d2caafad5c04191b5bb635c794043 399 SUPERFAMILY SSF48264 5 399 2.75E-81 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS26300 713d2caafad5c04191b5bb635c794043 399 PRINTS PR00359 B-class P450 signature 273 284 1.8E-51 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS26300 713d2caafad5c04191b5bb635c794043 399 PRINTS PR00359 B-class P450 signature 341 350 1.8E-51 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS26300 713d2caafad5c04191b5bb635c794043 399 PRINTS PR00359 B-class P450 signature 290 317 1.8E-51 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS26300 713d2caafad5c04191b5bb635c794043 399 PRINTS PR00359 B-class P450 signature 350 361 1.8E-51 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS26300 713d2caafad5c04191b5bb635c794043 399 PRINTS PR00359 B-class P450 signature 318 333 1.8E-51 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS26300 713d2caafad5c04191b5bb635c794043 399 PRINTS PR00359 B-class P450 signature 130 146 1.8E-51 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS26300 713d2caafad5c04191b5bb635c794043 399 PRINTS PR00359 B-class P450 signature 83 94 1.8E-51 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS26300 713d2caafad5c04191b5bb635c794043 399 PRINTS PR00359 B-class P450 signature 147 162 1.8E-51 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS26300 713d2caafad5c04191b5bb635c794043 399 PRINTS PR00359 B-class P450 signature 191 213 1.8E-51 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS26300 713d2caafad5c04191b5bb635c794043 399 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 343 352 - T 10-11-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A4G23_RS26300 713d2caafad5c04191b5bb635c794043 399 Pfam PF00067 Cytochrome P450 188 358 1.1E-19 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS26300 713d2caafad5c04191b5bb635c794043 399 PRINTS PR00385 P450 superfamily signature 341 350 9.3E-6 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS26300 713d2caafad5c04191b5bb635c794043 399 PRINTS PR00385 P450 superfamily signature 350 361 9.3E-6 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS26300 713d2caafad5c04191b5bb635c794043 399 PRINTS PR00385 P450 superfamily signature 273 284 9.3E-6 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS26300 713d2caafad5c04191b5bb635c794043 399 PRINTS PR00385 P450 superfamily signature 237 254 9.3E-6 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS07840 224bf0c495719b91b908b26bed7a29b4 234 SUPERFAMILY SSF158682 95 227 1.96E-6 T 10-11-2016 IPR029024 TerB-like A4G23_RS07840 224bf0c495719b91b908b26bed7a29b4 234 Pfam PF05099 Tellurite resistance protein TerB 94 226 7.5E-8 T 10-11-2016 IPR007791 Co-chaperone DjlA, N-terminal A4G23_RS07840 224bf0c495719b91b908b26bed7a29b4 234 Gene3D G3DSA:1.10.3680.10 182 229 0.001 T 10-11-2016 IPR029024 TerB-like A4G23_RS24925 f37372cf667efb674ea39cb59a0c788c 461 SUPERFAMILY SSF53383 32 438 1.02E-105 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS24925 f37372cf667efb674ea39cb59a0c788c 461 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 233 271 - T 10-11-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4G23_RS24925 f37372cf667efb674ea39cb59a0c788c 461 Gene3D G3DSA:3.90.1150.10 20 75 2.8E-34 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS24925 f37372cf667efb674ea39cb59a0c788c 461 Gene3D G3DSA:3.90.1150.10 323 438 2.8E-34 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS24925 f37372cf667efb674ea39cb59a0c788c 461 Pfam PF00202 Aminotransferase class-III 41 435 2.3E-86 T 10-11-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4G23_RS24925 f37372cf667efb674ea39cb59a0c788c 461 Gene3D G3DSA:3.40.640.10 76 322 2.1E-69 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS18705 b4ff7924380bf7d74bcaf4afa4835298 250 Pfam PF12138 Spherulation-specific family 4 23 243 4.7E-18 T 10-11-2016 IPR021986 Spherulation-specific family 4 A4G23_RS26785 b7357c9ad822d435c7304253dcc5c6cd 200 SUPERFAMILY SSF48498 64 177 1.78E-14 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS26785 b7357c9ad822d435c7304253dcc5c6cd 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 2 48 2.2E-8 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS26785 b7357c9ad822d435c7304253dcc5c6cd 200 Gene3D G3DSA:1.10.357.10 2 181 1.2E-39 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS26785 b7357c9ad822d435c7304253dcc5c6cd 200 SUPERFAMILY SSF46689 2 55 1.95E-11 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS23590 eeacbc6ec25c2265a67c29e590b0f1fa 306 SUPERFAMILY SSF56601 41 303 2.51E-74 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS23590 eeacbc6ec25c2265a67c29e590b0f1fa 306 Gene3D G3DSA:3.40.710.10 43 304 5.3E-93 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS23590 eeacbc6ec25c2265a67c29e590b0f1fa 306 PRINTS PR00118 Beta-lactamase class A signature 237 252 1.4E-60 T 10-11-2016 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 A4G23_RS23590 eeacbc6ec25c2265a67c29e590b0f1fa 306 PRINTS PR00118 Beta-lactamase class A signature 45 69 1.4E-60 T 10-11-2016 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 A4G23_RS23590 eeacbc6ec25c2265a67c29e590b0f1fa 306 PRINTS PR00118 Beta-lactamase class A signature 158 182 1.4E-60 T 10-11-2016 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 A4G23_RS23590 eeacbc6ec25c2265a67c29e590b0f1fa 306 PRINTS PR00118 Beta-lactamase class A signature 76 93 1.4E-60 T 10-11-2016 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 A4G23_RS23590 eeacbc6ec25c2265a67c29e590b0f1fa 306 PRINTS PR00118 Beta-lactamase class A signature 122 147 1.4E-60 T 10-11-2016 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 A4G23_RS23590 eeacbc6ec25c2265a67c29e590b0f1fa 306 PRINTS PR00118 Beta-lactamase class A signature 220 235 1.4E-60 T 10-11-2016 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 A4G23_RS23590 eeacbc6ec25c2265a67c29e590b0f1fa 306 PRINTS PR00118 Beta-lactamase class A signature 184 209 1.4E-60 T 10-11-2016 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 A4G23_RS23590 eeacbc6ec25c2265a67c29e590b0f1fa 306 Pfam PF13354 Beta-lactamase enzyme family 65 277 1.9E-39 T 10-11-2016 A4G23_RS11215 d65f74c58a19976b1609e5f3455305f5 326 Gene3D G3DSA:3.40.50.720 1 181 1.7E-63 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS11215 d65f74c58a19976b1609e5f3455305f5 326 SUPERFAMILY SSF51735 1 317 4.06E-103 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS11215 d65f74c58a19976b1609e5f3455305f5 326 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 2 317 3.0E-125 T 10-11-2016 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 A4G23_RS11215 d65f74c58a19976b1609e5f3455305f5 326 Gene3D G3DSA:3.90.25.10 182 318 1.9E-52 T 10-11-2016 A4G23_RS11215 d65f74c58a19976b1609e5f3455305f5 326 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 303 1.2E-77 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS05095 7097e2ab0e0aa20fbdf68aedbfd6b534 171 SUPERFAMILY SSF53254 6 155 6.64E-26 T 10-11-2016 IPR029033 Histidine phosphatase superfamily A4G23_RS05095 7097e2ab0e0aa20fbdf68aedbfd6b534 171 SMART SM00855 8 119 1.1E-6 T 10-11-2016 IPR013078 Histidine phosphatase superfamily, clade-1 A4G23_RS05095 7097e2ab0e0aa20fbdf68aedbfd6b534 171 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 9 104 2.2E-11 T 10-11-2016 IPR013078 Histidine phosphatase superfamily, clade-1 A4G23_RS05095 7097e2ab0e0aa20fbdf68aedbfd6b534 171 Gene3D G3DSA:3.40.50.1240 4 170 8.5E-55 T 10-11-2016 IPR029033 Histidine phosphatase superfamily A4G23_RS13410 016977fe484e3b1d108f4a63e2b977f5 182 Gene3D G3DSA:1.10.260.40 25 62 1.5E-6 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS13410 016977fe484e3b1d108f4a63e2b977f5 182 SUPERFAMILY SSF47413 22 75 3.87E-7 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS24975 a87b1c2f767ea280b2a14ca1bb6b1559 714 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 494 504 4.1E-25 T 10-11-2016 A4G23_RS24975 a87b1c2f767ea280b2a14ca1bb6b1559 714 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 331 345 4.1E-25 T 10-11-2016 A4G23_RS24975 a87b1c2f767ea280b2a14ca1bb6b1559 714 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 178 192 4.1E-25 T 10-11-2016 A4G23_RS24975 a87b1c2f767ea280b2a14ca1bb6b1559 714 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 570 582 4.1E-25 T 10-11-2016 A4G23_RS24975 a87b1c2f767ea280b2a14ca1bb6b1559 714 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 547 566 4.1E-25 T 10-11-2016 A4G23_RS24975 a87b1c2f767ea280b2a14ca1bb6b1559 714 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 100 368 5.2E-31 T 10-11-2016 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A4G23_RS24975 a87b1c2f767ea280b2a14ca1bb6b1559 714 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 401 632 3.6E-42 T 10-11-2016 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A4G23_RS24975 a87b1c2f767ea280b2a14ca1bb6b1559 714 Gene3D G3DSA:2.70.150.10 69 232 1.4E-23 T 10-11-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 A4G23_RS24975 a87b1c2f767ea280b2a14ca1bb6b1559 714 Gene3D G3DSA:3.40.50.1000 475 594 1.0E-36 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS24975 a87b1c2f767ea280b2a14ca1bb6b1559 714 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 43 707 0.0 T 10-11-2016 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 A4G23_RS24975 a87b1c2f767ea280b2a14ca1bb6b1559 714 Gene3D G3DSA:3.40.1110.10 342 474 5.9E-49 T 10-11-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A4G23_RS24975 a87b1c2f767ea280b2a14ca1bb6b1559 714 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 42 711 40.31 T 10-11-2016 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 A4G23_RS24975 a87b1c2f767ea280b2a14ca1bb6b1559 714 SUPERFAMILY SSF81665 232 325 1.44E-11 T 10-11-2016 A4G23_RS24975 a87b1c2f767ea280b2a14ca1bb6b1559 714 SUPERFAMILY SSF81665 67 131 1.44E-11 T 10-11-2016 A4G23_RS24975 a87b1c2f767ea280b2a14ca1bb6b1559 714 Pfam PF00702 haloacid dehalogenase-like hydrolase 328 561 5.6E-31 T 10-11-2016 A4G23_RS24975 a87b1c2f767ea280b2a14ca1bb6b1559 714 SUPERFAMILY SSF81653 132 231 1.96E-21 T 10-11-2016 A4G23_RS24975 a87b1c2f767ea280b2a14ca1bb6b1559 714 Pfam PF00122 E1-E2 ATPase 100 322 4.2E-44 T 10-11-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 A4G23_RS24975 a87b1c2f767ea280b2a14ca1bb6b1559 714 SUPERFAMILY SSF56784 466 590 1.57E-38 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS24975 a87b1c2f767ea280b2a14ca1bb6b1559 714 SUPERFAMILY SSF56784 319 343 1.57E-38 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS24975 a87b1c2f767ea280b2a14ca1bb6b1559 714 SUPERFAMILY SSF56784 399 431 1.57E-38 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS24975 a87b1c2f767ea280b2a14ca1bb6b1559 714 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 333 339 - T 10-11-2016 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 A4G23_RS06200 5a8fd883f106268a5fc2c210235d6ac8 1045 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 5 1043 13.826 T 10-11-2016 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A4G23_RS06200 5a8fd883f106268a5fc2c210235d6ac8 1045 Gene3D G3DSA:3.40.50.620 396 633 2.8E-136 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS06200 5a8fd883f106268a5fc2c210235d6ac8 1045 Gene3D G3DSA:3.40.50.620 7 196 2.8E-136 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS06200 5a8fd883f106268a5fc2c210235d6ac8 1045 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 7 836 1.1E-270 T 10-11-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A4G23_RS06200 5a8fd883f106268a5fc2c210235d6ac8 1045 SUPERFAMILY SSF52374 392 646 8.58E-124 T 10-11-2016 A4G23_RS06200 5a8fd883f106268a5fc2c210235d6ac8 1045 SUPERFAMILY SSF52374 7 200 8.58E-124 T 10-11-2016 A4G23_RS06200 5a8fd883f106268a5fc2c210235d6ac8 1045 SUPERFAMILY SSF47323 653 890 4.3E-50 T 10-11-2016 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4G23_RS06200 5a8fd883f106268a5fc2c210235d6ac8 1045 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 20 626 5.4E-168 T 10-11-2016 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4G23_RS06200 5a8fd883f106268a5fc2c210235d6ac8 1045 Gene3D G3DSA:3.90.740.10 227 395 3.6E-52 T 10-11-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A4G23_RS06200 5a8fd883f106268a5fc2c210235d6ac8 1045 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 557 566 1.9E-26 T 10-11-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A4G23_RS06200 5a8fd883f106268a5fc2c210235d6ac8 1045 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 390 405 1.9E-26 T 10-11-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A4G23_RS06200 5a8fd883f106268a5fc2c210235d6ac8 1045 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 517 530 1.9E-26 T 10-11-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A4G23_RS06200 5a8fd883f106268a5fc2c210235d6ac8 1045 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 226 249 1.9E-26 T 10-11-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A4G23_RS06200 5a8fd883f106268a5fc2c210235d6ac8 1045 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 43 54 1.9E-26 T 10-11-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A4G23_RS06200 5a8fd883f106268a5fc2c210235d6ac8 1045 Gene3D G3DSA:1.10.730.10 644 821 7.2E-49 T 10-11-2016 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4G23_RS06200 5a8fd883f106268a5fc2c210235d6ac8 1045 SUPERFAMILY SSF50677 203 392 1.47E-45 T 10-11-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A4G23_RS06200 5a8fd883f106268a5fc2c210235d6ac8 1045 Pfam PF08264 Anticodon-binding domain of tRNA 685 830 2.7E-31 T 10-11-2016 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 A4G23_RS09920 c1ff8ef70830703f1be515140e3c7e14 345 Pfam PF06271 RDD family 18 143 3.8E-19 T 10-11-2016 IPR010432 RDD A4G23_RS11325 c6535d4140d147084352feb0c3a05176 431 SUPERFAMILY SSF69318 233 412 1.44E-15 T 10-11-2016 A4G23_RS11325 c6535d4140d147084352feb0c3a05176 431 Gene3D G3DSA:2.115.10.10 174 316 2.5E-12 T 10-11-2016 IPR023294 Tachylectin 2 A4G23_RS11325 c6535d4140d147084352feb0c3a05176 431 Gene3D G3DSA:2.115.10.10 317 419 1.5E-12 T 10-11-2016 IPR023294 Tachylectin 2 A4G23_RS11325 c6535d4140d147084352feb0c3a05176 431 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 278 340 3.8E-6 T 10-11-2016 A4G23_RS09470 bdaee9daebfdcfcdfb10bedfba0df91e 509 Pfam PF01235 Sodium:alanine symporter family 81 493 1.7E-123 T 10-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A4G23_RS09470 bdaee9daebfdcfcdfb10bedfba0df91e 509 PRINTS PR00175 Sodium/alanine symporter signature 454 474 2.4E-44 T 10-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A4G23_RS09470 bdaee9daebfdcfcdfb10bedfba0df91e 509 PRINTS PR00175 Sodium/alanine symporter signature 393 415 2.4E-44 T 10-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A4G23_RS09470 bdaee9daebfdcfcdfb10bedfba0df91e 509 PRINTS PR00175 Sodium/alanine symporter signature 225 243 2.4E-44 T 10-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A4G23_RS09470 bdaee9daebfdcfcdfb10bedfba0df91e 509 PRINTS PR00175 Sodium/alanine symporter signature 253 272 2.4E-44 T 10-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A4G23_RS09470 bdaee9daebfdcfcdfb10bedfba0df91e 509 PRINTS PR00175 Sodium/alanine symporter signature 343 361 2.4E-44 T 10-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A4G23_RS09470 bdaee9daebfdcfcdfb10bedfba0df91e 509 PRINTS PR00175 Sodium/alanine symporter signature 115 137 2.4E-44 T 10-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A4G23_RS09470 bdaee9daebfdcfcdfb10bedfba0df91e 509 TIGRFAM TIGR00835 agcS: amino acid carrier protein 43 483 1.4E-111 T 10-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A4G23_RS23095 5ba410c0376c21b758ac18e40267027a 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 92 105 5.0E-7 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS23095 5ba410c0376c21b758ac18e40267027a 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 46 61 5.0E-7 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS23095 5ba410c0376c21b758ac18e40267027a 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 106 119 5.0E-7 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS23095 5ba410c0376c21b758ac18e40267027a 274 PRINTS PR00412 Epoxide hydrolase signature 26 44 7.4E-22 T 10-11-2016 IPR000639 Epoxide hydrolase-like GO:0003824 A4G23_RS23095 5ba410c0376c21b758ac18e40267027a 274 PRINTS PR00412 Epoxide hydrolase signature 92 105 7.4E-22 T 10-11-2016 IPR000639 Epoxide hydrolase-like GO:0003824 A4G23_RS23095 5ba410c0376c21b758ac18e40267027a 274 PRINTS PR00412 Epoxide hydrolase signature 106 119 7.4E-22 T 10-11-2016 IPR000639 Epoxide hydrolase-like GO:0003824 A4G23_RS23095 5ba410c0376c21b758ac18e40267027a 274 PRINTS PR00412 Epoxide hydrolase signature 46 61 7.4E-22 T 10-11-2016 IPR000639 Epoxide hydrolase-like GO:0003824 A4G23_RS23095 5ba410c0376c21b758ac18e40267027a 274 PRINTS PR00412 Epoxide hydrolase signature 247 269 7.4E-22 T 10-11-2016 IPR000639 Epoxide hydrolase-like GO:0003824 A4G23_RS23095 5ba410c0376c21b758ac18e40267027a 274 SUPERFAMILY SSF53474 4 273 1.18E-59 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS23095 5ba410c0376c21b758ac18e40267027a 274 Gene3D G3DSA:3.40.50.1820 3 273 1.1E-64 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS23095 5ba410c0376c21b758ac18e40267027a 274 Pfam PF12697 Alpha/beta hydrolase family 22 265 1.0E-21 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS17540 f0e8fe0f140140ba1d951d6a642d4752 328 SUPERFAMILY SSF53448 3 231 2.64E-44 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS17540 f0e8fe0f140140ba1d951d6a642d4752 328 Gene3D G3DSA:3.90.550.10 3 202 2.8E-43 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS17540 f0e8fe0f140140ba1d951d6a642d4752 328 Pfam PF00535 Glycosyl transferase family 2 5 129 1.0E-31 T 10-11-2016 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A4G23_RS04520 73e2153cde8ce6dcfdd2cd88b7ff2f25 179 SUPERFAMILY SSF55811 8 171 4.87E-30 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS04520 73e2153cde8ce6dcfdd2cd88b7ff2f25 179 Gene3D G3DSA:3.90.79.10 4 170 1.6E-49 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS04520 73e2153cde8ce6dcfdd2cd88b7ff2f25 179 ProSitePatterns PS00893 Nudix box signature. 71 92 - T 10-11-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A4G23_RS04520 73e2153cde8ce6dcfdd2cd88b7ff2f25 179 PIRSF PIRSF017340 1 174 1.2E-74 T 10-11-2016 IPR024195 NUDIX hydrolase, YfcD, predicted GO:0016817 A4G23_RS04520 73e2153cde8ce6dcfdd2cd88b7ff2f25 179 Pfam PF00293 NUDIX domain 34 148 2.9E-13 T 10-11-2016 IPR000086 NUDIX hydrolase domain GO:0016787 A4G23_RS09955 ad6c362762bc587a1670f5ed306bd905 453 SUPERFAMILY SSF55957 370 453 4.06E-19 T 10-11-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS09955 ad6c362762bc587a1670f5ed306bd905 453 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 375 451 9.3E-15 T 10-11-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS09955 ad6c362762bc587a1670f5ed306bd905 453 SUPERFAMILY SSF53738 262 366 5.49E-30 T 10-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS09955 ad6c362762bc587a1670f5ed306bd905 453 Gene3D G3DSA:3.40.120.10 175 252 2.2E-31 T 10-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS09955 ad6c362762bc587a1670f5ed306bd905 453 SUPERFAMILY SSF53738 7 122 6.28E-31 T 10-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS09955 ad6c362762bc587a1670f5ed306bd905 453 SUPERFAMILY SSF53738 157 258 7.85E-30 T 10-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS09955 ad6c362762bc587a1670f5ed306bd905 453 Gene3D G3DSA:3.40.120.10 9 122 1.0E-26 T 10-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS09955 ad6c362762bc587a1670f5ed306bd905 453 Gene3D G3DSA:3.40.120.10 253 370 7.3E-38 T 10-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS09955 ad6c362762bc587a1670f5ed306bd905 453 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 7 131 2.1E-29 T 10-11-2016 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS09955 ad6c362762bc587a1670f5ed306bd905 453 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 158 256 1.1E-25 T 10-11-2016 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS09955 ad6c362762bc587a1670f5ed306bd905 453 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 264 370 6.6E-26 T 10-11-2016 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS09955 ad6c362762bc587a1670f5ed306bd905 453 Gene3D G3DSA:3.30.310.50 372 452 1.4E-21 T 10-11-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS09955 ad6c362762bc587a1670f5ed306bd905 453 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 92 106 5.5E-22 T 10-11-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS09955 ad6c362762bc587a1670f5ed306bd905 453 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 236 251 5.5E-22 T 10-11-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS09955 ad6c362762bc587a1670f5ed306bd905 453 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 173 192 5.5E-22 T 10-11-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS09955 ad6c362762bc587a1670f5ed306bd905 453 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 207 220 5.5E-22 T 10-11-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS23040 52325dd01e5ae8a063d0f36206f1bbf6 465 Pfam PF01225 Mur ligase family, catalytic domain 13 109 3.0E-28 T 10-11-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 A4G23_RS23040 52325dd01e5ae8a063d0f36206f1bbf6 465 Pfam PF02875 Mur ligase family, glutamate ligase domain 317 404 2.3E-19 T 10-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4G23_RS23040 52325dd01e5ae8a063d0f36206f1bbf6 465 Gene3D G3DSA:3.90.190.20 319 463 4.6E-48 T 10-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4G23_RS23040 52325dd01e5ae8a063d0f36206f1bbf6 465 Pfam PF08245 Mur ligase middle domain 115 296 1.5E-20 T 10-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4G23_RS23040 52325dd01e5ae8a063d0f36206f1bbf6 465 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 13 458 8.6E-137 T 10-11-2016 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4G23_RS23040 52325dd01e5ae8a063d0f36206f1bbf6 465 SUPERFAMILY SSF53623 96 314 2.62E-52 T 10-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4G23_RS23040 52325dd01e5ae8a063d0f36206f1bbf6 465 Gene3D G3DSA:3.40.50.720 11 98 5.8E-34 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS23040 52325dd01e5ae8a063d0f36206f1bbf6 465 SUPERFAMILY SSF53244 316 462 1.08E-40 T 10-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4G23_RS23040 52325dd01e5ae8a063d0f36206f1bbf6 465 Gene3D G3DSA:3.40.1190.10 99 318 9.6E-69 T 10-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4G23_RS23040 52325dd01e5ae8a063d0f36206f1bbf6 465 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 9 465 37.87 T 10-11-2016 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4G23_RS23040 52325dd01e5ae8a063d0f36206f1bbf6 465 SUPERFAMILY SSF51984 10 98 4.32E-26 T 10-11-2016 A4G23_RS22120 e5b7e9f1c23b34ce0bad87ebc3a3c3e6 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 3.8E-7 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS22120 e5b7e9f1c23b34ce0bad87ebc3a3c3e6 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 3.8E-7 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS22120 e5b7e9f1c23b34ce0bad87ebc3a3c3e6 197 Gene3D G3DSA:1.10.357.10 2 191 3.7E-34 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS22120 e5b7e9f1c23b34ce0bad87ebc3a3c3e6 197 SUPERFAMILY SSF46689 3 88 9.23E-17 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS22120 e5b7e9f1c23b34ce0bad87ebc3a3c3e6 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 64 1.9E-14 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS09270 fe95b44c01f835e9f1507e64f7a13323 252 Pfam PF09339 IclR helix-turn-helix domain 14 63 5.5E-9 T 10-11-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4G23_RS09270 fe95b44c01f835e9f1507e64f7a13323 252 Gene3D G3DSA:1.10.10.10 10 79 8.1E-13 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS09270 fe95b44c01f835e9f1507e64f7a13323 252 Pfam PF01614 Bacterial transcriptional regulator 133 229 6.2E-13 T 10-11-2016 IPR014757 Transcription regulator IclR, C-terminal A4G23_RS09270 fe95b44c01f835e9f1507e64f7a13323 252 SUPERFAMILY SSF55781 77 241 2.16E-22 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS09270 fe95b44c01f835e9f1507e64f7a13323 252 SMART SM00346 11 100 0.0019 T 10-11-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4G23_RS09270 fe95b44c01f835e9f1507e64f7a13323 252 Gene3D G3DSA:3.30.450.40 89 241 2.5E-24 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS09270 fe95b44c01f835e9f1507e64f7a13323 252 SUPERFAMILY SSF46785 12 82 6.2E-12 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS02735 6e29b97ed1e34dfb119dd23b929d21a9 436 Gene3D G3DSA:3.40.50.2000 259 405 1.1E-32 T 10-11-2016 A4G23_RS02735 6e29b97ed1e34dfb119dd23b929d21a9 436 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 9 422 1.9E-53 T 10-11-2016 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 A4G23_RS02735 6e29b97ed1e34dfb119dd23b929d21a9 436 Gene3D G3DSA:3.40.50.2000 2 258 2.9E-21 T 10-11-2016 A4G23_RS02735 6e29b97ed1e34dfb119dd23b929d21a9 436 SUPERFAMILY SSF53756 3 425 1.73E-92 T 10-11-2016 A4G23_RS02735 6e29b97ed1e34dfb119dd23b929d21a9 436 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 202 409 8.5E-17 T 10-11-2016 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 A4G23_RS07955 e2e9e1cd4ca70d770cbc80a76d5dc6fc 622 Pfam PF00009 Elongation factor Tu GTP binding domain 19 200 1.0E-50 T 10-11-2016 A4G23_RS07955 e2e9e1cd4ca70d770cbc80a76d5dc6fc 622 Gene3D G3DSA:2.40.30.10 214 307 3.1E-19 T 10-11-2016 A4G23_RS07955 e2e9e1cd4ca70d770cbc80a76d5dc6fc 622 Pfam PF03144 Elongation factor Tu domain 2 224 294 1.5E-7 T 10-11-2016 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A4G23_RS07955 e2e9e1cd4ca70d770cbc80a76d5dc6fc 622 SMART SM00838 416 500 0.0012 T 10-11-2016 IPR000640 Translation elongation factor EFG, V domain A4G23_RS07955 e2e9e1cd4ca70d770cbc80a76d5dc6fc 622 TIGRFAM TIGR01393 lepA: elongation factor 4 19 614 9.0E-290 T 10-11-2016 IPR006297 Elongation factor 4 GO:0005525 A4G23_RS07955 e2e9e1cd4ca70d770cbc80a76d5dc6fc 622 Gene3D G3DSA:3.40.50.300 15 213 3.5E-56 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS07955 e2e9e1cd4ca70d770cbc80a76d5dc6fc 622 SUPERFAMILY SSF54980 417 512 1.39E-23 T 10-11-2016 IPR009022 Elongation factor G, III-V domain A4G23_RS07955 e2e9e1cd4ca70d770cbc80a76d5dc6fc 622 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 21 195 3.2E-19 T 10-11-2016 IPR005225 Small GTP-binding protein domain GO:0005525 A4G23_RS07955 e2e9e1cd4ca70d770cbc80a76d5dc6fc 622 PRINTS PR00315 GTP-binding elongation factor signature 93 103 4.8E-13 T 10-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4G23_RS07955 e2e9e1cd4ca70d770cbc80a76d5dc6fc 622 PRINTS PR00315 GTP-binding elongation factor signature 145 154 4.8E-13 T 10-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4G23_RS07955 e2e9e1cd4ca70d770cbc80a76d5dc6fc 622 PRINTS PR00315 GTP-binding elongation factor signature 64 72 4.8E-13 T 10-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4G23_RS07955 e2e9e1cd4ca70d770cbc80a76d5dc6fc 622 PRINTS PR00315 GTP-binding elongation factor signature 109 120 4.8E-13 T 10-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4G23_RS07955 e2e9e1cd4ca70d770cbc80a76d5dc6fc 622 PRINTS PR00315 GTP-binding elongation factor signature 21 34 4.8E-13 T 10-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4G23_RS07955 e2e9e1cd4ca70d770cbc80a76d5dc6fc 622 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 57 72 - T 10-11-2016 IPR031157 Tr-type G domain, conserved site A4G23_RS07955 e2e9e1cd4ca70d770cbc80a76d5dc6fc 622 Gene3D G3DSA:3.30.70.870 310 387 4.6E-25 T 10-11-2016 A4G23_RS07955 e2e9e1cd4ca70d770cbc80a76d5dc6fc 622 Pfam PF00679 Elongation factor G C-terminus 417 497 1.7E-21 T 10-11-2016 IPR000640 Translation elongation factor EFG, V domain A4G23_RS07955 e2e9e1cd4ca70d770cbc80a76d5dc6fc 622 Pfam PF06421 GTP-binding protein LepA C-terminus 507 612 2.8E-48 T 10-11-2016 IPR013842 GTP-binding protein LepA, C-terminal A4G23_RS07955 e2e9e1cd4ca70d770cbc80a76d5dc6fc 622 Gene3D G3DSA:3.30.70.240 419 507 3.3E-21 T 10-11-2016 IPR000640 Translation elongation factor EFG, V domain A4G23_RS07955 e2e9e1cd4ca70d770cbc80a76d5dc6fc 622 SUPERFAMILY SSF52540 13 222 1.64E-53 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS07955 e2e9e1cd4ca70d770cbc80a76d5dc6fc 622 Hamap MF_00071 Elongation factor 4 [lepA]. 1 616 281.943 T 10-11-2016 IPR006297 Elongation factor 4 GO:0005525 A4G23_RS07955 e2e9e1cd4ca70d770cbc80a76d5dc6fc 622 SUPERFAMILY SSF54980 310 389 1.51E-19 T 10-11-2016 IPR009022 Elongation factor G, III-V domain A4G23_RS07955 e2e9e1cd4ca70d770cbc80a76d5dc6fc 622 SUPERFAMILY SSF50447 202 300 2.4E-17 T 10-11-2016 IPR009000 Translation protein, beta-barrel domain A4G23_RS05355 6fb7a2cb45d540e44fe45897d77c1076 178 Gene3D G3DSA:3.40.630.30 16 172 8.2E-67 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS05355 6fb7a2cb45d540e44fe45897d77c1076 178 TIGRFAM TIGR02406 ectoine_EctA: diaminobutyrate acetyltransferase 16 171 9.4E-63 T 10-11-2016 IPR012772 L-2,4-diaminobutyric acid acetyltransferase GO:0019491|GO:0033816 KEGG: 00250+2.3.1.17|KEGG: 00260+2.3.1.178 A4G23_RS05355 6fb7a2cb45d540e44fe45897d77c1076 178 Pfam PF00583 Acetyltransferase (GNAT) family 62 136 4.4E-12 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS05355 6fb7a2cb45d540e44fe45897d77c1076 178 SUPERFAMILY SSF55729 16 135 9.64E-21 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS09620 7c125adeff1bf491be7f6cd28df8b6cc 598 Pfam PF06259 Alpha/beta hydrolase 366 532 3.3E-31 T 10-11-2016 IPR010427 Protein of unknown function DUF1023 A4G23_RS09620 7c125adeff1bf491be7f6cd28df8b6cc 598 SUPERFAMILY SSF53474 379 552 5.07E-8 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS20890 34075ffb7c2d9538a3c86cc8b216d2e1 333 Gene3D G3DSA:3.30.300.20 259 325 6.8E-30 T 10-11-2016 IPR015946 K homology domain-like, alpha/beta A4G23_RS20890 34075ffb7c2d9538a3c86cc8b216d2e1 333 Gene3D G3DSA:3.30.1480.10 4 102 1.3E-28 T 10-11-2016 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 A4G23_RS20890 34075ffb7c2d9538a3c86cc8b216d2e1 333 Gene3D G3DSA:2.40.50.140 109 179 1.3E-22 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS20890 34075ffb7c2d9538a3c86cc8b216d2e1 333 SUPERFAMILY SSF50249 113 180 1.71E-13 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS20890 34075ffb7c2d9538a3c86cc8b216d2e1 333 Gene3D G3DSA:3.30.300.20 180 258 5.5E-33 T 10-11-2016 IPR015946 K homology domain-like, alpha/beta A4G23_RS20890 34075ffb7c2d9538a3c86cc8b216d2e1 333 Pfam PF13184 NusA-like KH domain 211 279 1.2E-25 T 10-11-2016 IPR025249 KH domain, NusA-like GO:0003723 A4G23_RS20890 34075ffb7c2d9538a3c86cc8b216d2e1 333 SUPERFAMILY SSF69705 3 102 1.96E-26 T 10-11-2016 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 A4G23_RS20890 34075ffb7c2d9538a3c86cc8b216d2e1 333 SUPERFAMILY SSF54814 181 259 1.44E-27 T 10-11-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 A4G23_RS20890 34075ffb7c2d9538a3c86cc8b216d2e1 333 Pfam PF08529 NusA N-terminal domain 6 103 6.2E-16 T 10-11-2016 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 A4G23_RS20890 34075ffb7c2d9538a3c86cc8b216d2e1 333 SUPERFAMILY SSF54814 260 325 2.22E-15 T 10-11-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 A4G23_RS20890 34075ffb7c2d9538a3c86cc8b216d2e1 333 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 1 332 25.705 T 10-11-2016 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 A4G23_RS20890 34075ffb7c2d9538a3c86cc8b216d2e1 333 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 77 323 4.7E-97 T 10-11-2016 IPR010213 Transcription termination factor NusA GO:0003723 A4G23_RS21620 0ecf6e6e91a069b5693489071cf7ff7c 63 SMART SM00923 1 51 5.0E-19 T 10-11-2016 IPR005153 MbtH-like protein A4G23_RS21620 0ecf6e6e91a069b5693489071cf7ff7c 63 Pfam PF03621 MbtH-like protein 6 50 3.3E-20 T 10-11-2016 IPR005153 MbtH-like protein A4G23_RS21620 0ecf6e6e91a069b5693489071cf7ff7c 63 Gene3D G3DSA:3.90.820.10 9 62 5.2E-27 T 10-11-2016 A4G23_RS21620 0ecf6e6e91a069b5693489071cf7ff7c 63 SUPERFAMILY SSF160582 6 62 1.31E-24 T 10-11-2016 A4G23_RS19490 6275a6cb36db8f38cabd8151ada37ba5 704 Pfam PF07498 Rho termination factor, N-terminal domain 40 78 2.4E-11 T 10-11-2016 IPR011112 Rho termination factor, N-terminal GO:0006353 A4G23_RS19490 6275a6cb36db8f38cabd8151ada37ba5 704 Gene3D G3DSA:3.40.50.300 410 693 1.3E-98 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS19490 6275a6cb36db8f38cabd8151ada37ba5 704 SUPERFAMILY SSF50249 330 402 1.4E-16 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS19490 6275a6cb36db8f38cabd8151ada37ba5 704 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 435 639 9.2E-20 T 10-11-2016 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A4G23_RS19490 6275a6cb36db8f38cabd8151ada37ba5 704 SMART SM00382 446 631 5.5E-8 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS19490 6275a6cb36db8f38cabd8151ada37ba5 704 SMART SM00357 331 397 1.1E-10 T 10-11-2016 IPR011129 Cold shock protein GO:0003676 A4G23_RS19490 6275a6cb36db8f38cabd8151ada37ba5 704 Hamap MF_01884 Transcription termination factor Rho [rho]. 322 695 203.151 T 10-11-2016 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 A4G23_RS19490 6275a6cb36db8f38cabd8151ada37ba5 704 SMART SM00959 39 80 8.7E-11 T 10-11-2016 IPR011112 Rho termination factor, N-terminal GO:0006353 A4G23_RS19490 6275a6cb36db8f38cabd8151ada37ba5 704 Gene3D G3DSA:2.40.50.140 325 404 1.4E-40 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS19490 6275a6cb36db8f38cabd8151ada37ba5 704 Gene3D G3DSA:2.40.50.140 39 79 1.4E-40 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS19490 6275a6cb36db8f38cabd8151ada37ba5 704 SUPERFAMILY SSF52540 370 646 2.03E-66 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS19490 6275a6cb36db8f38cabd8151ada37ba5 704 Pfam PF07497 Rho termination factor, RNA-binding domain 330 403 2.7E-28 T 10-11-2016 IPR011113 Rho termination factor, RNA-binding GO:0003723|GO:0006353 A4G23_RS19490 6275a6cb36db8f38cabd8151ada37ba5 704 SUPERFAMILY SSF68912 39 78 6.28E-5 T 10-11-2016 IPR011112 Rho termination factor, N-terminal GO:0006353 A4G23_RS19490 6275a6cb36db8f38cabd8151ada37ba5 704 TIGRFAM TIGR00767 rho: transcription termination factor Rho 40 693 5.6E-199 T 10-11-2016 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 A4G23_RS06475 8d3a4901965c30d33fcdbab5b4508b21 598 Pfam PF00501 AMP-binding enzyme 23 466 5.6E-104 T 10-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A4G23_RS06475 8d3a4901965c30d33fcdbab5b4508b21 598 Gene3D G3DSA:3.40.50.980 334 396 1.5E-28 T 10-11-2016 A4G23_RS06475 8d3a4901965c30d33fcdbab5b4508b21 598 Gene3D G3DSA:3.40.50.980 190 283 1.5E-28 T 10-11-2016 A4G23_RS06475 8d3a4901965c30d33fcdbab5b4508b21 598 Gene3D G3DSA:3.40.50.980 17 189 2.4E-36 T 10-11-2016 A4G23_RS06475 8d3a4901965c30d33fcdbab5b4508b21 598 Gene3D G3DSA:2.30.38.10 397 457 1.2E-20 T 10-11-2016 A4G23_RS06475 8d3a4901965c30d33fcdbab5b4508b21 598 SUPERFAMILY SSF56801 17 288 4.45E-119 T 10-11-2016 A4G23_RS06475 8d3a4901965c30d33fcdbab5b4508b21 598 SUPERFAMILY SSF56801 337 596 4.45E-119 T 10-11-2016 A4G23_RS06475 8d3a4901965c30d33fcdbab5b4508b21 598 Gene3D G3DSA:3.30.300.30 464 584 3.2E-5 T 10-11-2016 A4G23_RS06475 8d3a4901965c30d33fcdbab5b4508b21 598 ProSitePatterns PS00455 Putative AMP-binding domain signature. 183 194 - T 10-11-2016 IPR020845 AMP-binding, conserved site A4G23_RS09040 5f5f9d08c29beb656a0c526e798ed832 409 SUPERFAMILY SSF46689 231 279 4.18E-8 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS09040 5f5f9d08c29beb656a0c526e798ed832 409 SUPERFAMILY SSF52317 23 211 4.38E-46 T 10-11-2016 IPR029062 Class I glutamine amidotransferase-like A4G23_RS09040 5f5f9d08c29beb656a0c526e798ed832 409 Gene3D G3DSA:3.40.50.880 23 237 4.0E-48 T 10-11-2016 IPR029062 Class I glutamine amidotransferase-like A4G23_RS09040 5f5f9d08c29beb656a0c526e798ed832 409 Pfam PF01965 DJ-1/PfpI family 58 190 2.3E-14 T 10-11-2016 IPR002818 DJ-1/PfpI A4G23_RS09040 5f5f9d08c29beb656a0c526e798ed832 409 Gene3D G3DSA:1.10.10.60 283 332 3.6E-11 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS09040 5f5f9d08c29beb656a0c526e798ed832 409 Pfam PF12833 Helix-turn-helix domain 252 330 6.3E-19 T 10-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4G23_RS09040 5f5f9d08c29beb656a0c526e798ed832 409 SUPERFAMILY SSF46689 283 333 1.48E-9 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS09040 5f5f9d08c29beb656a0c526e798ed832 409 Gene3D G3DSA:1.10.10.60 238 282 1.9E-12 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS09040 5f5f9d08c29beb656a0c526e798ed832 409 SMART SM00342 246 329 2.3E-21 T 10-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4G23_RS07700 b0aa3cac4fa5b740dd3b9af100daa20f 253 SUPERFAMILY SSF53800 6 234 9.27E-35 T 10-11-2016 A4G23_RS07700 b0aa3cac4fa5b740dd3b9af100daa20f 253 Pfam PF01903 CbiX 11 110 7.5E-18 T 10-11-2016 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 A4G23_RS07700 b0aa3cac4fa5b740dd3b9af100daa20f 253 Pfam PF01903 CbiX 136 227 1.4E-11 T 10-11-2016 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 A4G23_RS07700 b0aa3cac4fa5b740dd3b9af100daa20f 253 Gene3D G3DSA:3.40.50.1400 5 120 4.4E-26 T 10-11-2016 A4G23_RS07700 b0aa3cac4fa5b740dd3b9af100daa20f 253 Gene3D G3DSA:3.40.50.1400 128 236 8.7E-23 T 10-11-2016 A4G23_RS08560 e998dfc15f36d2f21cab3a86cee9eab4 622 SUPERFAMILY SSF52540 96 303 2.99E-23 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS08560 e998dfc15f36d2f21cab3a86cee9eab4 622 Pfam PF01926 50S ribosome-binding GTPase 106 224 2.6E-7 T 10-11-2016 IPR006073 GTP binding domain GO:0005525 A4G23_RS08560 e998dfc15f36d2f21cab3a86cee9eab4 622 Gene3D G3DSA:3.40.50.300 89 302 6.7E-25 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS20850 1c51769142e8fc209ab22175da745ac6 281 Pfam PF13312 Domain of unknown function (DUF4081) 48 152 3.1E-44 T 10-11-2016 IPR025289 Domain of unknown function DUF4081 A4G23_RS20850 1c51769142e8fc209ab22175da745ac6 281 PIRSF PIRSF021603 1 281 2.1E-137 T 10-11-2016 IPR016794 Uncharacterised conserved protein UCP21603, acetyltransferase-like A4G23_RS20850 1c51769142e8fc209ab22175da745ac6 281 Pfam PF00583 Acetyltransferase (GNAT) family 210 271 6.3E-10 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS20850 1c51769142e8fc209ab22175da745ac6 281 SUPERFAMILY SSF55729 8 276 1.1E-19 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS20850 1c51769142e8fc209ab22175da745ac6 281 Gene3D G3DSA:3.40.630.30 129 277 6.7E-21 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS24480 c7d9d22c8e614b7720d147955342878a 668 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 167 456 2.4E-8 T 10-11-2016 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 A4G23_RS24480 c7d9d22c8e614b7720d147955342878a 668 SUPERFAMILY SSF53649 333 602 3.66E-15 T 10-11-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 A4G23_RS24480 c7d9d22c8e614b7720d147955342878a 668 SUPERFAMILY SSF53649 164 283 3.66E-15 T 10-11-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 A4G23_RS24480 c7d9d22c8e614b7720d147955342878a 668 Gene3D G3DSA:3.40.720.10 144 316 9.2E-15 T 10-11-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 A4G23_RS24480 c7d9d22c8e614b7720d147955342878a 668 Gene3D G3DSA:3.40.720.10 359 439 9.2E-15 T 10-11-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 A4G23_RS24480 c7d9d22c8e614b7720d147955342878a 668 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 15 126 4.6E-11 T 10-11-2016 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV A4G23_RS09550 4f9880618bf27cb76650a2bfcb6b223d 214 SMART SM00346 6 93 3.3E-15 T 10-11-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4G23_RS09550 4f9880618bf27cb76650a2bfcb6b223d 214 SUPERFAMILY SSF55781 67 213 4.22E-17 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS09550 4f9880618bf27cb76650a2bfcb6b223d 214 Pfam PF09339 IclR helix-turn-helix domain 8 58 1.4E-14 T 10-11-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4G23_RS09550 4f9880618bf27cb76650a2bfcb6b223d 214 Gene3D G3DSA:3.30.450.40 157 213 3.0E-5 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS09550 4f9880618bf27cb76650a2bfcb6b223d 214 SUPERFAMILY SSF46785 7 76 2.13E-15 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS09550 4f9880618bf27cb76650a2bfcb6b223d 214 Gene3D G3DSA:1.10.10.10 5 76 4.7E-20 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS09550 4f9880618bf27cb76650a2bfcb6b223d 214 Gene3D G3DSA:3.30.450.40 80 146 1.2E-12 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS13195 f3023a5f23394ae61d742f9eaf5c18d3 250 Gene3D G3DSA:3.40.50.300 11 233 4.6E-70 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS13195 f3023a5f23394ae61d742f9eaf5c18d3 250 SMART SM00382 42 229 6.4E-15 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS13195 f3023a5f23394ae61d742f9eaf5c18d3 250 Pfam PF00005 ABC transporter 33 181 1.4E-33 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS13195 f3023a5f23394ae61d742f9eaf5c18d3 250 SUPERFAMILY SSF52540 13 234 8.87E-68 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS13195 f3023a5f23394ae61d742f9eaf5c18d3 250 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS05065 39f67b65f5a9a13f1166709e7a87eb04 226 SMART SM00448 18 131 2.8E-33 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS05065 39f67b65f5a9a13f1166709e7a87eb04 226 SUPERFAMILY SSF46894 161 225 3.37E-23 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS05065 39f67b65f5a9a13f1166709e7a87eb04 226 Gene3D G3DSA:1.10.10.10 168 224 1.7E-30 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS05065 39f67b65f5a9a13f1166709e7a87eb04 226 Pfam PF00196 Bacterial regulatory proteins, luxR family 164 219 2.2E-21 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS05065 39f67b65f5a9a13f1166709e7a87eb04 226 SUPERFAMILY SSF52172 18 147 1.12E-36 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS05065 39f67b65f5a9a13f1166709e7a87eb04 226 ProSitePatterns PS00622 LuxR-type HTH domain signature. 179 206 - T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS05065 39f67b65f5a9a13f1166709e7a87eb04 226 Pfam PF00072 Response regulator receiver domain 20 131 2.8E-30 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS05065 39f67b65f5a9a13f1166709e7a87eb04 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 179 3.7E-16 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS05065 39f67b65f5a9a13f1166709e7a87eb04 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 195 3.7E-16 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS05065 39f67b65f5a9a13f1166709e7a87eb04 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 195 207 3.7E-16 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS05065 39f67b65f5a9a13f1166709e7a87eb04 226 SMART SM00421 162 219 6.0E-28 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS05065 39f67b65f5a9a13f1166709e7a87eb04 226 Gene3D G3DSA:3.40.50.2300 17 167 1.6E-42 T 10-11-2016 A4G23_RS20895 000e7d98f70c599d345ca257210e3055 1022 PRINTS PR00315 GTP-binding elongation factor signature 571 581 1.1E-9 T 10-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4G23_RS20895 000e7d98f70c599d345ca257210e3055 1022 PRINTS PR00315 GTP-binding elongation factor signature 623 632 1.1E-9 T 10-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4G23_RS20895 000e7d98f70c599d345ca257210e3055 1022 PRINTS PR00315 GTP-binding elongation factor signature 587 598 1.1E-9 T 10-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4G23_RS20895 000e7d98f70c599d345ca257210e3055 1022 PRINTS PR00315 GTP-binding elongation factor signature 519 532 1.1E-9 T 10-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4G23_RS20895 000e7d98f70c599d345ca257210e3055 1022 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 436 481 9.8E-7 T 10-11-2016 IPR006847 Translation initiation factor IF-2, N-terminal A4G23_RS20895 000e7d98f70c599d345ca257210e3055 1022 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 2 50 5.6E-12 T 10-11-2016 IPR006847 Translation initiation factor IF-2, N-terminal A4G23_RS20895 000e7d98f70c599d345ca257210e3055 1022 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 1021 16.719 T 10-11-2016 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 A4G23_RS20895 000e7d98f70c599d345ca257210e3055 1022 SUPERFAMILY SSF50447 693 776 1.51E-24 T 10-11-2016 IPR009000 Translation protein, beta-barrel domain A4G23_RS20895 000e7d98f70c599d345ca257210e3055 1022 Pfam PF11987 Translation-initiation factor 2 810 912 1.1E-33 T 10-11-2016 IPR023115 Translation initiation factor IF- 2, domain 3 A4G23_RS20895 000e7d98f70c599d345ca257210e3055 1022 Gene3D G3DSA:3.40.50.300 516 679 1.8E-44 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS20895 000e7d98f70c599d345ca257210e3055 1022 Gene3D G3DSA:2.40.30.10 691 785 4.2E-23 T 10-11-2016 A4G23_RS20895 000e7d98f70c599d345ca257210e3055 1022 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 518 676 6.7E-29 T 10-11-2016 IPR005225 Small GTP-binding protein domain GO:0005525 A4G23_RS20895 000e7d98f70c599d345ca257210e3055 1022 SUPERFAMILY SSF52540 511 682 3.86E-47 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS20895 000e7d98f70c599d345ca257210e3055 1022 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 427 1021 6.9E-229 T 10-11-2016 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 A4G23_RS20895 000e7d98f70c599d345ca257210e3055 1022 SUPERFAMILY SSF50447 923 1021 7.46E-26 T 10-11-2016 IPR009000 Translation protein, beta-barrel domain A4G23_RS20895 000e7d98f70c599d345ca257210e3055 1022 Gene3D G3DSA:2.40.30.10 924 1021 1.3E-30 T 10-11-2016 A4G23_RS20895 000e7d98f70c599d345ca257210e3055 1022 ProSitePatterns PS01176 Initiation factor 2 signature. 974 996 - T 10-11-2016 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 A4G23_RS20895 000e7d98f70c599d345ca257210e3055 1022 SUPERFAMILY SSF52156 800 929 1.26E-35 T 10-11-2016 IPR023115 Translation initiation factor IF- 2, domain 3 A4G23_RS20895 000e7d98f70c599d345ca257210e3055 1022 Pfam PF00009 Elongation factor Tu GTP binding domain 520 680 5.9E-32 T 10-11-2016 A4G23_RS20895 000e7d98f70c599d345ca257210e3055 1022 Gene3D G3DSA:3.40.50.10050 821 901 2.0E-22 T 10-11-2016 IPR023115 Translation initiation factor IF- 2, domain 3 A4G23_RS18375 cb6d03c7c30dc11d8edf5b7959cde32b 251 Pfam PF07702 UTRA domain 112 243 1.6E-14 T 10-11-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A4G23_RS18375 cb6d03c7c30dc11d8edf5b7959cde32b 251 SMART SM00345 12 71 1.0E-10 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS18375 cb6d03c7c30dc11d8edf5b7959cde32b 251 SUPERFAMILY SSF46785 5 82 2.72E-18 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS18375 cb6d03c7c30dc11d8edf5b7959cde32b 251 Gene3D G3DSA:3.40.1410.10 73 246 3.6E-54 T 10-11-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain A4G23_RS18375 cb6d03c7c30dc11d8edf5b7959cde32b 251 SMART SM00866 99 243 4.4E-14 T 10-11-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A4G23_RS18375 cb6d03c7c30dc11d8edf5b7959cde32b 251 SUPERFAMILY SSF64288 59 249 4.71E-24 T 10-11-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain A4G23_RS18375 cb6d03c7c30dc11d8edf5b7959cde32b 251 Gene3D G3DSA:1.10.10.10 8 72 5.1E-21 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS18375 cb6d03c7c30dc11d8edf5b7959cde32b 251 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 71 1.4E-14 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS12925 71cda4e3a7e92665b37c5e2153c0023b 303 SUPERFAMILY SSF52540 1 217 7.65E-57 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS12925 71cda4e3a7e92665b37c5e2153c0023b 303 Gene3D G3DSA:3.40.50.300 1 218 1.3E-62 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS12925 71cda4e3a7e92665b37c5e2153c0023b 303 ProSitePatterns PS00211 ABC transporters family signature. 128 142 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS12925 71cda4e3a7e92665b37c5e2153c0023b 303 Pfam PF00005 ABC transporter 18 155 6.2E-26 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS12925 71cda4e3a7e92665b37c5e2153c0023b 303 SMART SM00382 26 234 2.0E-9 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS07880 4bcdef507562933359b9d8bdcd90b5a9 431 SUPERFAMILY SSF56176 336 428 7.09E-13 T 10-11-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 A4G23_RS07880 4bcdef507562933359b9d8bdcd90b5a9 431 Pfam PF01595 Domain of unknown function DUF21 8 185 7.4E-32 T 10-11-2016 IPR002550 Domain of unknown function DUF21 A4G23_RS07880 4bcdef507562933359b9d8bdcd90b5a9 431 SMART SM01091 337 423 1.0E-14 T 10-11-2016 IPR005170 Transporter-associated domain A4G23_RS07880 4bcdef507562933359b9d8bdcd90b5a9 431 SMART SM00116 274 322 0.1 T 10-11-2016 IPR000644 CBS domain A4G23_RS07880 4bcdef507562933359b9d8bdcd90b5a9 431 SMART SM00116 209 258 1.4E-4 T 10-11-2016 IPR000644 CBS domain A4G23_RS07880 4bcdef507562933359b9d8bdcd90b5a9 431 Pfam PF00571 CBS domain 200 256 3.7E-8 T 10-11-2016 IPR000644 CBS domain A4G23_RS07880 4bcdef507562933359b9d8bdcd90b5a9 431 Pfam PF00571 CBS domain 272 322 4.7E-7 T 10-11-2016 IPR000644 CBS domain A4G23_RS07880 4bcdef507562933359b9d8bdcd90b5a9 431 Gene3D G3DSA:3.10.580.10 186 329 9.7E-25 T 10-11-2016 A4G23_RS07880 4bcdef507562933359b9d8bdcd90b5a9 431 SUPERFAMILY SSF54631 195 339 2.78E-36 T 10-11-2016 A4G23_RS07880 4bcdef507562933359b9d8bdcd90b5a9 431 Gene3D G3DSA:3.30.465.10 330 420 5.1E-20 T 10-11-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 A4G23_RS07880 4bcdef507562933359b9d8bdcd90b5a9 431 Pfam PF03471 Transporter associated domain 339 421 8.9E-13 T 10-11-2016 IPR005170 Transporter-associated domain A4G23_RS26220 76348514f777480e3427da9f5c1517d2 499 SMART SM00014 67 176 2.9E-18 T 10-11-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A4G23_RS26220 76348514f777480e3427da9f5c1517d2 499 SUPERFAMILY SSF111331 203 496 3.71E-44 T 10-11-2016 IPR016064 NAD kinase/diacylglycerol kinase-like domain A4G23_RS26220 76348514f777480e3427da9f5c1517d2 499 SUPERFAMILY SSF48317 7 184 4.97E-36 T 10-11-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A4G23_RS26220 76348514f777480e3427da9f5c1517d2 499 Gene3D G3DSA:1.20.144.10 5 179 7.4E-32 T 10-11-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A4G23_RS26220 76348514f777480e3427da9f5c1517d2 499 Pfam PF00781 Diacylglycerol kinase catalytic domain 204 325 9.8E-15 T 10-11-2016 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 A4G23_RS26220 76348514f777480e3427da9f5c1517d2 499 Pfam PF01569 PAP2 superfamily 70 180 2.3E-18 T 10-11-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A4G23_RS26220 76348514f777480e3427da9f5c1517d2 499 SMART SM00046 203 328 0.0029 T 10-11-2016 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 A4G23_RS01580 ae1f248bbbb65b5165076c168272feca 567 SUPERFAMILY SSF52540 35 347 3.7E-50 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS01580 ae1f248bbbb65b5165076c168272feca 567 Pfam PF16124 RecQ zinc-binding 433 482 8.8E-13 T 10-11-2016 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain A4G23_RS01580 ae1f248bbbb65b5165076c168272feca 567 Pfam PF00271 Helicase conserved C-terminal domain 241 335 1.5E-13 T 10-11-2016 IPR001650 Helicase, C-terminal A4G23_RS01580 ae1f248bbbb65b5165076c168272feca 567 Pfam PF12073 Protein of unknown function (DUF3553) 517 550 2.7E-4 T 10-11-2016 IPR021938 Protein of unknown function DUF3553 A4G23_RS01580 ae1f248bbbb65b5165076c168272feca 567 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 19 354 2.7E-96 T 10-11-2016 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 A4G23_RS01580 ae1f248bbbb65b5165076c168272feca 567 Pfam PF00270 DEAD/DEAH box helicase 28 187 4.9E-12 T 10-11-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A4G23_RS01580 ae1f248bbbb65b5165076c168272feca 567 SMART SM00487 22 220 5.0E-22 T 10-11-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4G23_RS01580 ae1f248bbbb65b5165076c168272feca 567 Gene3D G3DSA:1.10.10.10 369 422 3.7E-5 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS01580 ae1f248bbbb65b5165076c168272feca 567 Gene3D G3DSA:3.40.50.300 13 199 6.5E-40 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS01580 ae1f248bbbb65b5165076c168272feca 567 SMART SM00490 254 335 1.8E-23 T 10-11-2016 IPR001650 Helicase, C-terminal A4G23_RS01580 ae1f248bbbb65b5165076c168272feca 567 Gene3D G3DSA:3.40.50.300 209 350 3.9E-37 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS01580 ae1f248bbbb65b5165076c168272feca 567 Gene3D G3DSA:1.10.10.10 435 485 4.6E-17 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS01550 4a81d9603afeaf2842fb5335376a8a18 223 Pfam PF00075 RNase H 5 144 5.2E-26 T 10-11-2016 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 A4G23_RS01550 4a81d9603afeaf2842fb5335376a8a18 223 Hamap MF_00042 Ribonuclease H [rnhA]. 2 154 31.979 T 10-11-2016 IPR022892 Ribonuclease H GO:0004523 A4G23_RS01550 4a81d9603afeaf2842fb5335376a8a18 223 Gene3D G3DSA:3.30.420.10 3 147 2.2E-42 T 10-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 A4G23_RS01550 4a81d9603afeaf2842fb5335376a8a18 223 SUPERFAMILY SSF53098 4 143 8.09E-38 T 10-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 A4G23_RS21430 c7dca614f57ae39e420e6398aa18967d 226 SMART SM00345 8 66 7.3E-18 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS21430 c7dca614f57ae39e420e6398aa18967d 226 SUPERFAMILY SSF46785 6 70 3.67E-20 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS21430 c7dca614f57ae39e420e6398aa18967d 226 Gene3D G3DSA:1.10.10.10 5 67 2.8E-22 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS21430 c7dca614f57ae39e420e6398aa18967d 226 Pfam PF00392 Bacterial regulatory proteins, gntR family 5 66 3.7E-18 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS21430 c7dca614f57ae39e420e6398aa18967d 226 SMART SM00895 76 198 9.6E-20 T 10-11-2016 IPR011711 GntR, C-terminal A4G23_RS21430 c7dca614f57ae39e420e6398aa18967d 226 SUPERFAMILY SSF48008 73 201 2.88E-23 T 10-11-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal A4G23_RS21430 c7dca614f57ae39e420e6398aa18967d 226 Gene3D G3DSA:1.20.120.530 69 201 1.3E-24 T 10-11-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal A4G23_RS21430 c7dca614f57ae39e420e6398aa18967d 226 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 3.6E-7 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS21430 c7dca614f57ae39e420e6398aa18967d 226 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 3.6E-7 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS21430 c7dca614f57ae39e420e6398aa18967d 226 Pfam PF07729 FCD domain 76 198 1.6E-23 T 10-11-2016 IPR011711 GntR, C-terminal A4G23_RS16145 9ee5ee2368e14c21d4aa067e5be5b050 457 Gene3D G3DSA:2.60.120.260 345 457 3.2E-16 T 10-11-2016 IPR008979 Galactose-binding domain-like A4G23_RS16145 9ee5ee2368e14c21d4aa067e5be5b050 457 Pfam PF04389 Peptidase family M28 124 329 3.4E-49 T 10-11-2016 IPR007484 Peptidase M28 A4G23_RS16145 9ee5ee2368e14c21d4aa067e5be5b050 457 Pfam PF01483 Proprotein convertase P-domain 378 457 6.4E-19 T 10-11-2016 IPR002884 Proprotein convertase, P GO:0004252|GO:0006508 A4G23_RS16145 9ee5ee2368e14c21d4aa067e5be5b050 457 SUPERFAMILY SSF53187 68 333 5.19E-73 T 10-11-2016 A4G23_RS16145 9ee5ee2368e14c21d4aa067e5be5b050 457 SUPERFAMILY SSF49785 352 457 1.11E-24 T 10-11-2016 IPR008979 Galactose-binding domain-like A4G23_RS16145 9ee5ee2368e14c21d4aa067e5be5b050 457 Gene3D G3DSA:3.40.630.10 65 334 2.8E-79 T 10-11-2016 A4G23_RS13300 e1f051f787e8500bd73649f049977373 353 SUPERFAMILY SSF63380 2 110 6.27E-24 T 10-11-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 A4G23_RS13300 e1f051f787e8500bd73649f049977373 353 Gene3D G3DSA:3.40.50.80 98 237 2.1E-35 T 10-11-2016 A4G23_RS13300 e1f051f787e8500bd73649f049977373 353 SUPERFAMILY SSF54292 234 350 1.44E-25 T 10-11-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A4G23_RS13300 e1f051f787e8500bd73649f049977373 353 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 300 308 - T 10-11-2016 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 A4G23_RS13300 e1f051f787e8500bd73649f049977373 353 Pfam PF00970 Oxidoreductase FAD-binding domain 5 106 3.6E-11 T 10-11-2016 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 A4G23_RS13300 e1f051f787e8500bd73649f049977373 353 PRINTS PR00410 Phenol hydroxylase reductase family signature 116 135 2.7E-6 T 10-11-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 A4G23_RS13300 e1f051f787e8500bd73649f049977373 353 PRINTS PR00410 Phenol hydroxylase reductase family signature 101 110 2.7E-6 T 10-11-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 A4G23_RS13300 e1f051f787e8500bd73649f049977373 353 PRINTS PR00410 Phenol hydroxylase reductase family signature 212 220 2.7E-6 T 10-11-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 A4G23_RS13300 e1f051f787e8500bd73649f049977373 353 PRINTS PR00410 Phenol hydroxylase reductase family signature 54 61 2.7E-6 T 10-11-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 A4G23_RS13300 e1f051f787e8500bd73649f049977373 353 Pfam PF00175 Oxidoreductase NAD-binding domain 119 226 2.9E-10 T 10-11-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 A4G23_RS13300 e1f051f787e8500bd73649f049977373 353 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 269 341 1.8E-13 T 10-11-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A4G23_RS13300 e1f051f787e8500bd73649f049977373 353 Gene3D G3DSA:3.10.20.30 238 347 2.0E-28 T 10-11-2016 IPR012675 Beta-grasp domain A4G23_RS13300 e1f051f787e8500bd73649f049977373 353 SUPERFAMILY SSF52343 95 242 1.26E-31 T 10-11-2016 A4G23_RS13300 e1f051f787e8500bd73649f049977373 353 Gene3D G3DSA:2.40.30.10 2 97 1.3E-24 T 10-11-2016 A4G23_RS10185 5bc4438470848df1271bb612452fbe50 337 SUPERFAMILY SSF51735 2 320 4.06E-74 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS10185 5bc4438470848df1271bb612452fbe50 337 Hamap MF_00955 GDP-mannose 4,6-dehydratase [gmd]. 3 326 54.247 T 10-11-2016 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 A4G23_RS10185 5bc4438470848df1271bb612452fbe50 337 Gene3D G3DSA:3.90.25.10 203 327 6.0E-47 T 10-11-2016 A4G23_RS10185 5bc4438470848df1271bb612452fbe50 337 Pfam PF16363 GDP-mannose 4,6 dehydratase 6 316 2.2E-131 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS10185 5bc4438470848df1271bb612452fbe50 337 TIGRFAM TIGR01472 gmd: GDP-mannose 4,6-dehydratase 3 322 1.9E-149 T 10-11-2016 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 A4G23_RS10185 5bc4438470848df1271bb612452fbe50 337 Gene3D G3DSA:3.40.50.720 3 202 2.8E-40 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS01800 5a783bc5d11f50e03fdab2a2eed571a9 159 Pfam PF13581 Histidine kinase-like ATPase domain 14 105 8.1E-10 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS01800 5a783bc5d11f50e03fdab2a2eed571a9 159 SUPERFAMILY SSF55874 18 108 1.2E-8 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS09555 2a003edb26b919e04bba62610a6f919a 562 SMART SM00487 3 165 1.4E-7 T 10-11-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4G23_RS09555 2a003edb26b919e04bba62610a6f919a 562 Gene3D G3DSA:3.40.50.300 9 146 1.4E-14 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS09555 2a003edb26b919e04bba62610a6f919a 562 Gene3D G3DSA:3.40.50.300 254 370 3.6E-7 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS09555 2a003edb26b919e04bba62610a6f919a 562 SUPERFAMILY SSF52540 8 145 1.63E-25 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS09555 2a003edb26b919e04bba62610a6f919a 562 SUPERFAMILY SSF52540 214 350 1.63E-25 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS09555 2a003edb26b919e04bba62610a6f919a 562 Pfam PF04851 Type III restriction enzyme, res subunit 6 143 8.4E-12 T 10-11-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 A4G23_RS07425 dd8fe3f7ed69747030a712fe1b619454 133 Pfam PF03995 Peptidase inhibitor family I36 38 106 9.2E-8 T 10-11-2016 A4G23_RS08130 cbb076d0c78d55ba931571cf8e2c349c 84 PRINTS PR00063 Ribosomal protein L27 signature 29 53 7.3E-35 T 10-11-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS08130 cbb076d0c78d55ba931571cf8e2c349c 84 PRINTS PR00063 Ribosomal protein L27 signature 4 28 7.3E-35 T 10-11-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS08130 cbb076d0c78d55ba931571cf8e2c349c 84 PRINTS PR00063 Ribosomal protein L27 signature 54 78 7.3E-35 T 10-11-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS08130 cbb076d0c78d55ba931571cf8e2c349c 84 Pfam PF01016 Ribosomal L27 protein 2 80 5.8E-35 T 10-11-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS08130 cbb076d0c78d55ba931571cf8e2c349c 84 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 71 2.0E-17 T 10-11-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS08130 cbb076d0c78d55ba931571cf8e2c349c 84 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 81 6.9E-35 T 10-11-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS08130 cbb076d0c78d55ba931571cf8e2c349c 84 Gene3D G3DSA:2.40.50.100 20 82 9.3E-28 T 10-11-2016 A4G23_RS08130 cbb076d0c78d55ba931571cf8e2c349c 84 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 83 26.746 T 10-11-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS08130 cbb076d0c78d55ba931571cf8e2c349c 84 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 10-11-2016 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS08130 cbb076d0c78d55ba931571cf8e2c349c 84 SUPERFAMILY SSF110324 2 81 1.5E-30 T 10-11-2016 A4G23_RS26815 050c2b4842096c5ccf7fbe50fd74c333 448 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 57 185 5.3E-48 T 10-11-2016 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 A4G23_RS26815 050c2b4842096c5ccf7fbe50fd74c333 448 Gene3D G3DSA:1.10.285.10 5 67 1.4E-25 T 10-11-2016 A4G23_RS26815 050c2b4842096c5ccf7fbe50fd74c333 448 Gene3D G3DSA:1.10.285.10 372 447 1.4E-20 T 10-11-2016 A4G23_RS26815 050c2b4842096c5ccf7fbe50fd74c333 448 PIRSF PIRSF000185 22 448 6.8E-120 T 10-11-2016 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 A4G23_RS26815 050c2b4842096c5ccf7fbe50fd74c333 448 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 194 216 2.4E-29 T 10-11-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 A4G23_RS26815 050c2b4842096c5ccf7fbe50fd74c333 448 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 236 256 2.4E-29 T 10-11-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 A4G23_RS26815 050c2b4842096c5ccf7fbe50fd74c333 448 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 371 382 2.4E-29 T 10-11-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 A4G23_RS26815 050c2b4842096c5ccf7fbe50fd74c333 448 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 114 128 2.4E-29 T 10-11-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 A4G23_RS26815 050c2b4842096c5ccf7fbe50fd74c333 448 SMART SM00839 205 446 2.4E-81 T 10-11-2016 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 A4G23_RS26815 050c2b4842096c5ccf7fbe50fd74c333 448 Gene3D G3DSA:3.40.192.10 68 188 1.8E-60 T 10-11-2016 A4G23_RS26815 050c2b4842096c5ccf7fbe50fd74c333 448 Gene3D G3DSA:3.40.50.720 210 371 6.6E-59 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS26815 050c2b4842096c5ccf7fbe50fd74c333 448 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 203 446 3.0E-83 T 10-11-2016 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 A4G23_RS26815 050c2b4842096c5ccf7fbe50fd74c333 448 SUPERFAMILY SSF51735 203 447 9.94E-72 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS26815 050c2b4842096c5ccf7fbe50fd74c333 448 SUPERFAMILY SSF53223 7 197 3.52E-74 T 10-11-2016 A4G23_RS16155 f89d1ab508debfbc4e93d0f7c670ac53 366 TIGRFAM TIGR00688 rarD: protein RarD 13 264 5.8E-63 T 10-11-2016 IPR004626 RarD protein GO:0005215|GO:0005887|GO:0006810 A4G23_RS16155 f89d1ab508debfbc4e93d0f7c670ac53 366 SUPERFAMILY SSF103481 55 151 3.01E-12 T 10-11-2016 A4G23_RS16155 f89d1ab508debfbc4e93d0f7c670ac53 366 Pfam PF00892 EamA-like transporter family 14 149 2.3E-8 T 10-11-2016 IPR000620 EamA domain GO:0016020|GO:0016021 A4G23_RS16155 f89d1ab508debfbc4e93d0f7c670ac53 366 SUPERFAMILY SSF103481 208 292 9.81E-10 T 10-11-2016 A4G23_RS03300 64b19d57fa81fd715f4e5d7f0bd6c38b 537 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 431 519 7.2E-11 T 10-11-2016 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 A4G23_RS03300 64b19d57fa81fd715f4e5d7f0bd6c38b 537 SUPERFAMILY SSF49785 419 529 1.98E-11 T 10-11-2016 IPR008979 Galactose-binding domain-like A4G23_RS03300 64b19d57fa81fd715f4e5d7f0bd6c38b 537 SUPERFAMILY SSF53474 74 362 5.88E-43 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS03300 64b19d57fa81fd715f4e5d7f0bd6c38b 537 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 78 371 2.7E-20 T 10-11-2016 IPR005674 CocE/Serine esterase GO:0016787 A4G23_RS03300 64b19d57fa81fd715f4e5d7f0bd6c38b 537 Gene3D G3DSA:3.40.50.1820 254 359 9.5E-50 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS03300 64b19d57fa81fd715f4e5d7f0bd6c38b 537 Gene3D G3DSA:3.40.50.1820 40 202 9.5E-50 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS03300 64b19d57fa81fd715f4e5d7f0bd6c38b 537 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 75 307 1.3E-31 T 10-11-2016 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 A4G23_RS03300 64b19d57fa81fd715f4e5d7f0bd6c38b 537 Gene3D G3DSA:2.60.120.260 419 512 6.9E-10 T 10-11-2016 IPR008979 Galactose-binding domain-like A4G23_RS03300 64b19d57fa81fd715f4e5d7f0bd6c38b 537 SMART SM00939 326 535 1.0E-12 T 10-11-2016 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 A4G23_RS19785 9a68a8571418e2ade59a8f82f0a6af55 696 Pfam PF01515 Phosphate acetyl/butaryl transferase 366 683 4.9E-125 T 10-11-2016 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 A4G23_RS19785 9a68a8571418e2ade59a8f82f0a6af55 696 Gene3D G3DSA:3.40.50.300 3 203 5.1E-6 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS19785 9a68a8571418e2ade59a8f82f0a6af55 696 Pfam PF13500 AAA domain 3 205 1.5E-17 T 10-11-2016 A4G23_RS19785 9a68a8571418e2ade59a8f82f0a6af55 696 SUPERFAMILY SSF53659 365 686 1.36E-93 T 10-11-2016 A4G23_RS19785 9a68a8571418e2ade59a8f82f0a6af55 696 Gene3D G3DSA:3.40.1390.20 204 342 1.3E-26 T 10-11-2016 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like A4G23_RS19785 9a68a8571418e2ade59a8f82f0a6af55 696 Gene3D G3DSA:3.40.50.10750 501 659 9.5E-67 T 10-11-2016 A4G23_RS19785 9a68a8571418e2ade59a8f82f0a6af55 696 SUPERFAMILY SSF52540 4 215 4.09E-9 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS19785 9a68a8571418e2ade59a8f82f0a6af55 696 SUPERFAMILY SSF75138 204 322 1.65E-19 T 10-11-2016 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like A4G23_RS19785 9a68a8571418e2ade59a8f82f0a6af55 696 Pfam PF07085 DRTGG domain 210 319 1.8E-22 T 10-11-2016 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 A4G23_RS19785 9a68a8571418e2ade59a8f82f0a6af55 696 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 382 683 6.0E-119 T 10-11-2016 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 A4G23_RS00425 b8693b535962f4c58f1a1600200a1ae9 333 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 235 250 4.2E-9 T 10-11-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 A4G23_RS00425 b8693b535962f4c58f1a1600200a1ae9 333 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 95 113 4.2E-9 T 10-11-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 A4G23_RS00425 b8693b535962f4c58f1a1600200a1ae9 333 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 121 145 4.2E-9 T 10-11-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 A4G23_RS00425 b8693b535962f4c58f1a1600200a1ae9 333 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 179 199 4.2E-9 T 10-11-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 A4G23_RS00425 b8693b535962f4c58f1a1600200a1ae9 333 Pfam PF00326 Prolyl oligopeptidase family 119 319 7.9E-42 T 10-11-2016 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 A4G23_RS00425 b8693b535962f4c58f1a1600200a1ae9 333 SUPERFAMILY SSF53474 67 318 5.77E-60 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS00425 b8693b535962f4c58f1a1600200a1ae9 333 Gene3D G3DSA:3.40.50.1820 63 318 3.4E-67 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS01395 bfe1e49d9a0f1bf5a4ecf03a9b4db3c0 414 SUPERFAMILY SSF53850 33 380 7.24E-58 T 10-11-2016 A4G23_RS01395 bfe1e49d9a0f1bf5a4ecf03a9b4db3c0 414 Pfam PF01547 Bacterial extracellular solute-binding protein 69 314 1.3E-22 T 10-11-2016 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 A4G23_RS01395 bfe1e49d9a0f1bf5a4ecf03a9b4db3c0 414 Gene3D G3DSA:3.40.190.10 70 152 1.5E-13 T 10-11-2016 A4G23_RS01395 bfe1e49d9a0f1bf5a4ecf03a9b4db3c0 414 Gene3D G3DSA:3.40.190.10 153 346 7.2E-39 T 10-11-2016 A4G23_RS25745 9b4741767bbd0e2e13aa90bd76a1ce9f 401 SMART SM00387 283 393 1.8E-5 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS25745 9b4741767bbd0e2e13aa90bd76a1ce9f 401 Pfam PF06580 Histidine kinase 194 272 1.4E-21 T 10-11-2016 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 A4G23_RS25745 9b4741767bbd0e2e13aa90bd76a1ce9f 401 SUPERFAMILY SSF55874 250 390 3.54E-18 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS25745 9b4741767bbd0e2e13aa90bd76a1ce9f 401 Gene3D G3DSA:3.30.565.10 249 392 2.4E-15 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS25745 9b4741767bbd0e2e13aa90bd76a1ce9f 401 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 292 391 6.3E-8 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS16365 57659dc1c17eb566f06170b7c64e217e 127 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 61 127 1.6E-27 T 10-11-2016 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS16365 57659dc1c17eb566f06170b7c64e217e 127 Gene3D G3DSA:3.30.1390.10 55 127 1.6E-30 T 10-11-2016 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like A4G23_RS16365 57659dc1c17eb566f06170b7c64e217e 127 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 62 106 3.0E-18 T 10-11-2016 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS16365 57659dc1c17eb566f06170b7c64e217e 127 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 127 1.6E-46 T 10-11-2016 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS16365 57659dc1c17eb566f06170b7c64e217e 127 SUPERFAMILY SSF54736 56 127 2.27E-22 T 10-11-2016 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like A4G23_RS16365 57659dc1c17eb566f06170b7c64e217e 127 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 6 53 2.7E-18 T 10-11-2016 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS16365 57659dc1c17eb566f06170b7c64e217e 127 SUPERFAMILY SSF48300 5 63 7.32E-15 T 10-11-2016 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS16365 57659dc1c17eb566f06170b7c64e217e 127 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 3 127 22.434 T 10-11-2016 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS16365 57659dc1c17eb566f06170b7c64e217e 127 Gene3D G3DSA:1.20.5.710 3 54 6.3E-20 T 10-11-2016 A4G23_RS23380 9b8a31e6844fff85c62ac10f712b9d69 310 SUPERFAMILY SSF110581 6 302 1.83E-96 T 10-11-2016 A4G23_RS23380 9b8a31e6844fff85c62ac10f712b9d69 310 Hamap MF_01876 Pseudouridine-5'-phosphate glycosidase [psuG]. 11 304 38.67 T 10-11-2016 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 A4G23_RS23380 9b8a31e6844fff85c62ac10f712b9d69 310 Pfam PF04227 Indigoidine synthase A like protein 12 300 2.8E-108 T 10-11-2016 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 A4G23_RS21615 2c19e5bc749c3c242b8549434eea2203 614 Gene3D G3DSA:3.40.50.980 16 173 1.2E-37 T 10-11-2016 A4G23_RS21615 2c19e5bc749c3c242b8549434eea2203 614 Pfam PF13193 AMP-binding enzyme C-terminal domain 432 507 3.0E-9 T 10-11-2016 IPR025110 AMP-binding enzyme C-terminal domain A4G23_RS21615 2c19e5bc749c3c242b8549434eea2203 614 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 43 448 5.4E-100 T 10-11-2016 IPR010071 Amino acid adenylation domain A4G23_RS21615 2c19e5bc749c3c242b8549434eea2203 614 Gene3D G3DSA:3.40.50.980 174 343 7.6E-37 T 10-11-2016 A4G23_RS21615 2c19e5bc749c3c242b8549434eea2203 614 SUPERFAMILY SSF47336 538 604 2.88E-12 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS21615 2c19e5bc749c3c242b8549434eea2203 614 SMART SM00823 Phosphopantetheine attachment site 539 607 4.5E-4 T 10-11-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4G23_RS21615 2c19e5bc749c3c242b8549434eea2203 614 Pfam PF00501 AMP-binding enzyme 23 424 1.6E-77 T 10-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A4G23_RS21615 2c19e5bc749c3c242b8549434eea2203 614 ProSitePatterns PS00455 Putative AMP-binding domain signature. 166 177 - T 10-11-2016 IPR020845 AMP-binding, conserved site A4G23_RS21615 2c19e5bc749c3c242b8549434eea2203 614 Gene3D G3DSA:3.30.300.30 418 519 1.1E-24 T 10-11-2016 A4G23_RS21615 2c19e5bc749c3c242b8549434eea2203 614 Gene3D G3DSA:1.10.1200.10 536 606 1.2E-15 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS21615 2c19e5bc749c3c242b8549434eea2203 614 Pfam PF00550 Phosphopantetheine attachment site 541 603 8.7E-12 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS21615 2c19e5bc749c3c242b8549434eea2203 614 Gene3D G3DSA:2.30.38.10 344 411 9.9E-13 T 10-11-2016 A4G23_RS21615 2c19e5bc749c3c242b8549434eea2203 614 SUPERFAMILY SSF56801 9 521 2.09E-126 T 10-11-2016 A4G23_RS01665 d8dd6e909a955dee1fe7a6c6bbab9af2 320 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 314 4.3E-23 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS01665 d8dd6e909a955dee1fe7a6c6bbab9af2 320 Gene3D G3DSA:1.10.3720.10 37 310 4.6E-57 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS01665 d8dd6e909a955dee1fe7a6c6bbab9af2 320 SUPERFAMILY SSF161098 83 307 2.09E-52 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS22675 07183670aadf1dd2b547463122b1ba94 124 Gene3D G3DSA:3.10.180.10 3 122 1.5E-15 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS22675 07183670aadf1dd2b547463122b1ba94 124 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 120 1.5E-4 T 10-11-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4G23_RS22675 07183670aadf1dd2b547463122b1ba94 124 SUPERFAMILY SSF54593 3 122 2.75E-18 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS22705 a536e06ebee28baf3606b03bb0f43690 241 Pfam PF13545 Crp-like helix-turn-helix domain 148 221 5.3E-15 T 10-11-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A4G23_RS22705 a536e06ebee28baf3606b03bb0f43690 241 SUPERFAMILY SSF46785 146 225 3.1E-16 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS22705 a536e06ebee28baf3606b03bb0f43690 241 SMART SM00419 167 215 3.5E-10 T 10-11-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A4G23_RS22705 a536e06ebee28baf3606b03bb0f43690 241 Gene3D G3DSA:1.10.10.10 146 224 3.8E-20 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS22705 a536e06ebee28baf3606b03bb0f43690 241 Pfam PF00027 Cyclic nucleotide-binding domain 29 114 4.9E-16 T 10-11-2016 IPR000595 Cyclic nucleotide-binding domain A4G23_RS22705 a536e06ebee28baf3606b03bb0f43690 241 Gene3D G3DSA:2.60.120.10 9 134 1.2E-23 T 10-11-2016 IPR014710 RmlC-like jelly roll fold A4G23_RS22705 a536e06ebee28baf3606b03bb0f43690 241 SMART SM00100 10 128 8.6E-19 T 10-11-2016 IPR000595 Cyclic nucleotide-binding domain A4G23_RS22705 a536e06ebee28baf3606b03bb0f43690 241 SUPERFAMILY SSF51206 7 135 6.81E-24 T 10-11-2016 IPR018490 Cyclic nucleotide-binding-like A4G23_RS08365 2705ec4b53d42d209addb982f282c965 477 Pfam PF00324 Amino acid permease 34 447 7.4E-113 T 10-11-2016 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 A4G23_RS08365 2705ec4b53d42d209addb982f282c965 477 PIRSF PIRSF006060 7 472 1.2E-73 T 10-11-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A4G23_RS08365 2705ec4b53d42d209addb982f282c965 477 ProSitePatterns PS00218 Amino acid permeases signature. 59 89 - T 10-11-2016 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 A4G23_RS26980 3297b92833ef7716b28f2327c84d7859 266 SMART SM00947 109 266 2.8E-34 T 10-11-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A4G23_RS26980 3297b92833ef7716b28f2327c84d7859 266 Pfam PF00484 Carbonic anhydrase 116 259 7.3E-31 T 10-11-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A4G23_RS26980 3297b92833ef7716b28f2327c84d7859 266 Gene3D G3DSA:3.40.1050.10 74 265 1.6E-43 T 10-11-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A4G23_RS26980 3297b92833ef7716b28f2327c84d7859 266 SUPERFAMILY SSF53056 74 265 4.32E-38 T 10-11-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A4G23_RS24285 c77299de2cd7e1105781bb63ec3c4a75 662 Gene3D G3DSA:3.40.50.280 497 648 3.4E-50 T 10-11-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A4G23_RS24285 c77299de2cd7e1105781bb63ec3c4a75 662 Pfam PF01642 Methylmalonyl-CoA mutase 1 479 1.6E-131 T 10-11-2016 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A4G23_RS24285 c77299de2cd7e1105781bb63ec3c4a75 662 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 1 485 1.6E-137 T 10-11-2016 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A4G23_RS24285 c77299de2cd7e1105781bb63ec3c4a75 662 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 520 649 1.2E-40 T 10-11-2016 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A4G23_RS24285 c77299de2cd7e1105781bb63ec3c4a75 662 Pfam PF02310 B12 binding domain 523 629 3.0E-19 T 10-11-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A4G23_RS24285 c77299de2cd7e1105781bb63ec3c4a75 662 Gene3D G3DSA:3.20.20.240 1 480 3.3E-186 T 10-11-2016 IPR014348 Cobalamin (vitamin B12)-dependent enzyme, catalytic subdomain GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A4G23_RS24285 c77299de2cd7e1105781bb63ec3c4a75 662 SUPERFAMILY SSF52242 501 642 3.14E-44 T 10-11-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A4G23_RS24285 c77299de2cd7e1105781bb63ec3c4a75 662 SUPERFAMILY SSF51703 1 481 7.85E-161 T 10-11-2016 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A4G23_RS03980 adf8915d46f5d7b5622623163fac7b4e 397 SUPERFAMILY SSF69864 171 394 2.49E-85 T 10-11-2016 A4G23_RS03980 adf8915d46f5d7b5622623163fac7b4e 397 TIGRFAM TIGR00032 argG: argininosuccinate synthase 4 392 2.4E-147 T 10-11-2016 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4G23_RS03980 adf8915d46f5d7b5622623163fac7b4e 397 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 117 128 - T 10-11-2016 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4G23_RS03980 adf8915d46f5d7b5622623163fac7b4e 397 Gene3D G3DSA:3.40.50.620 3 173 2.4E-56 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS03980 adf8915d46f5d7b5622623163fac7b4e 397 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 8 16 - T 10-11-2016 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4G23_RS03980 adf8915d46f5d7b5622623163fac7b4e 397 Gene3D G3DSA:3.90.1260.10 174 394 9.1E-83 T 10-11-2016 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4G23_RS03980 adf8915d46f5d7b5622623163fac7b4e 397 Pfam PF00764 Arginosuccinate synthase 6 391 4.0E-186 T 10-11-2016 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4G23_RS03980 adf8915d46f5d7b5622623163fac7b4e 397 Hamap MF_00005 Argininosuccinate synthase [argG]. 2 396 52.126 T 10-11-2016 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4G23_RS03980 adf8915d46f5d7b5622623163fac7b4e 397 SUPERFAMILY SSF52402 3 165 3.31E-43 T 10-11-2016 A4G23_RS07560 3ba90155e519346c087088dfaaa2ac84 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 48 66 5.7E-34 T 10-11-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 A4G23_RS07560 3ba90155e519346c087088dfaaa2ac84 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 302 328 5.7E-34 T 10-11-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 A4G23_RS07560 3ba90155e519346c087088dfaaa2ac84 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 68 91 5.7E-34 T 10-11-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 A4G23_RS07560 3ba90155e519346c087088dfaaa2ac84 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 133 152 5.7E-34 T 10-11-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 A4G23_RS07560 3ba90155e519346c087088dfaaa2ac84 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 188 208 5.7E-34 T 10-11-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 A4G23_RS07560 3ba90155e519346c087088dfaaa2ac84 347 Gene3D G3DSA:3.30.420.40 12 159 2.0E-21 T 10-11-2016 A4G23_RS07560 3ba90155e519346c087088dfaaa2ac84 347 SUPERFAMILY SSF53067 11 149 3.56E-21 T 10-11-2016 A4G23_RS07560 3ba90155e519346c087088dfaaa2ac84 347 SUPERFAMILY SSF53067 151 329 1.36E-30 T 10-11-2016 A4G23_RS07560 3ba90155e519346c087088dfaaa2ac84 347 Pfam PF06723 MreB/Mbl protein 11 333 1.2E-105 T 10-11-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 A4G23_RS07560 3ba90155e519346c087088dfaaa2ac84 347 Gene3D G3DSA:3.30.420.40 160 187 1.4E-22 T 10-11-2016 A4G23_RS07560 3ba90155e519346c087088dfaaa2ac84 347 Gene3D G3DSA:3.30.420.40 265 319 1.4E-22 T 10-11-2016 A4G23_RS07560 3ba90155e519346c087088dfaaa2ac84 347 Gene3D G3DSA:3.90.640.10 188 261 2.2E-11 T 10-11-2016 A4G23_RS01135 c9ea7add645ecca821351a291bdb0370 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 250 7.2E-62 T 10-11-2016 A4G23_RS01135 c9ea7add645ecca821351a291bdb0370 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 10-11-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4G23_RS01135 c9ea7add645ecca821351a291bdb0370 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 2.3E-39 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS01135 c9ea7add645ecca821351a291bdb0370 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 2.3E-39 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS01135 c9ea7add645ecca821351a291bdb0370 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 2.3E-39 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS01135 c9ea7add645ecca821351a291bdb0370 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 2.3E-39 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS01135 c9ea7add645ecca821351a291bdb0370 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.3E-39 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS01135 c9ea7add645ecca821351a291bdb0370 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 2.3E-39 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS01135 c9ea7add645ecca821351a291bdb0370 252 Gene3D G3DSA:3.40.50.720 2 251 8.0E-76 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS01135 c9ea7add645ecca821351a291bdb0370 252 SUPERFAMILY SSF51735 7 251 4.58E-75 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS01135 c9ea7add645ecca821351a291bdb0370 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 2.2E-7 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS01135 c9ea7add645ecca821351a291bdb0370 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 2.2E-7 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS01135 c9ea7add645ecca821351a291bdb0370 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 2.2E-7 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS00470 f596cdfef382d96875ff8722de39e216 253 SUPERFAMILY SSF53335 22 240 7.21E-40 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS00470 f596cdfef382d96875ff8722de39e216 253 Pfam PF13649 Methyltransferase domain 40 132 1.2E-16 T 10-11-2016 A4G23_RS00470 f596cdfef382d96875ff8722de39e216 253 Gene3D G3DSA:3.40.50.150 190 229 9.8E-33 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS00470 f596cdfef382d96875ff8722de39e216 253 Gene3D G3DSA:3.40.50.150 25 141 9.8E-33 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS22060 96c89d49d58273aa5b290c477acf42fb 381 SUPERFAMILY SSF50022 17 157 8.9E-33 T 10-11-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A4G23_RS22060 96c89d49d58273aa5b290c477acf42fb 381 Pfam PF00355 Rieske [2Fe-2S] domain 45 121 3.5E-12 T 10-11-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A4G23_RS22060 96c89d49d58273aa5b290c477acf42fb 381 Gene3D G3DSA:3.90.380.10 148 359 3.8E-19 T 10-11-2016 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 A4G23_RS22060 96c89d49d58273aa5b290c477acf42fb 381 Gene3D G3DSA:2.102.10.10 44 147 8.1E-18 T 10-11-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A4G23_RS22060 96c89d49d58273aa5b290c477acf42fb 381 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 178 370 7.7E-33 T 10-11-2016 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 A4G23_RS22060 96c89d49d58273aa5b290c477acf42fb 381 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 29 54 2.1E-21 T 10-11-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 A4G23_RS22060 96c89d49d58273aa5b290c477acf42fb 381 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 141 167 2.1E-21 T 10-11-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 A4G23_RS22060 96c89d49d58273aa5b290c477acf42fb 381 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 79 99 2.1E-21 T 10-11-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 A4G23_RS22060 96c89d49d58273aa5b290c477acf42fb 381 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 178 200 2.1E-21 T 10-11-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 A4G23_RS22060 96c89d49d58273aa5b290c477acf42fb 381 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 100 120 2.1E-21 T 10-11-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 A4G23_RS22060 96c89d49d58273aa5b290c477acf42fb 381 SUPERFAMILY SSF55961 158 374 1.81E-35 T 10-11-2016 A4G23_RS16855 db12739cdbec85a7d5c7c72851d2f1c5 403 SMART SM00530 12 66 1.2E-5 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS16855 db12739cdbec85a7d5c7c72851d2f1c5 403 Pfam PF13560 Helix-turn-helix domain 10 65 1.8E-7 T 10-11-2016 A4G23_RS16855 db12739cdbec85a7d5c7c72851d2f1c5 403 Gene3D G3DSA:1.25.40.10 117 228 5.2E-4 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS16855 db12739cdbec85a7d5c7c72851d2f1c5 403 SUPERFAMILY SSF47413 8 68 5.07E-9 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS16855 db12739cdbec85a7d5c7c72851d2f1c5 403 Gene3D G3DSA:1.10.260.40 9 70 5.2E-10 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS16795 6178869a28fe3fdc0fe8d5e70deab348 122 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 2 120 8.0E-26 T 10-11-2016 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 A4G23_RS16795 6178869a28fe3fdc0fe8d5e70deab348 122 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 4 104 7.9E-14 T 10-11-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 A4G23_RS16795 6178869a28fe3fdc0fe8d5e70deab348 122 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 8 83 3.0E-14 T 10-11-2016 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 A4G23_RS16795 6178869a28fe3fdc0fe8d5e70deab348 122 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 1 121 2.4E-21 T 10-11-2016 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 A4G23_RS16795 6178869a28fe3fdc0fe8d5e70deab348 122 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 3 122 22.69 T 10-11-2016 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 A4G23_RS16795 6178869a28fe3fdc0fe8d5e70deab348 122 SUPERFAMILY SSF56214 1 121 8.24E-27 T 10-11-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 A4G23_RS16795 6178869a28fe3fdc0fe8d5e70deab348 122 Gene3D G3DSA:3.90.470.20 1 121 6.5E-42 T 10-11-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 A4G23_RS08450 d46fb9cad861205448e56b2e6dfa34cc 697 SUPERFAMILY SSF51445 146 571 4.0E-136 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS08450 d46fb9cad861205448e56b2e6dfa34cc 697 SUPERFAMILY SSF51445 601 681 4.0E-136 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS08450 d46fb9cad861205448e56b2e6dfa34cc 697 Pfam PF02446 4-alpha-glucanotransferase 150 655 6.1E-113 T 10-11-2016 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 A4G23_RS08450 d46fb9cad861205448e56b2e6dfa34cc 697 Gene3D G3DSA:3.20.20.80 146 658 4.1E-157 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS08450 d46fb9cad861205448e56b2e6dfa34cc 697 TIGRFAM TIGR00217 malQ: 4-alpha-glucanotransferase 110 654 4.1E-85 T 10-11-2016 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 A4G23_RS14155 1c3eda4881de548ad5ed6c8b7fe46f9e 470 SUPERFAMILY SSF103365 15 470 9.68E-151 T 10-11-2016 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 A4G23_RS14155 1c3eda4881de548ad5ed6c8b7fe46f9e 470 ProSitePatterns PS01288 Uncharacterized protein family UPF0027 signature. 41 70 - T 10-11-2016 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 A4G23_RS14155 1c3eda4881de548ad5ed6c8b7fe46f9e 470 Pfam PF01139 tRNA-splicing ligase RtcB 41 470 9.1E-144 T 10-11-2016 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 A4G23_RS09170 9242817cfff898f414d5b511af5f5ccc 475 PRINTS PR00131 Glycosyl hydrolase family 1 signature 297 311 3.3E-22 T 10-11-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A4G23_RS09170 9242817cfff898f414d5b511af5f5ccc 475 PRINTS PR00131 Glycosyl hydrolase family 1 signature 398 409 3.3E-22 T 10-11-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A4G23_RS09170 9242817cfff898f414d5b511af5f5ccc 475 PRINTS PR00131 Glycosyl hydrolase family 1 signature 443 455 3.3E-22 T 10-11-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A4G23_RS09170 9242817cfff898f414d5b511af5f5ccc 475 PRINTS PR00131 Glycosyl hydrolase family 1 signature 377 385 3.3E-22 T 10-11-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A4G23_RS09170 9242817cfff898f414d5b511af5f5ccc 475 PRINTS PR00131 Glycosyl hydrolase family 1 signature 419 436 3.3E-22 T 10-11-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A4G23_RS09170 9242817cfff898f414d5b511af5f5ccc 475 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 19 33 - T 10-11-2016 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site A4G23_RS09170 9242817cfff898f414d5b511af5f5ccc 475 SUPERFAMILY SSF51445 14 472 2.74E-161 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS09170 9242817cfff898f414d5b511af5f5ccc 475 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 377 385 - T 10-11-2016 IPR018120 Glycoside hydrolase family 1, active site A4G23_RS09170 9242817cfff898f414d5b511af5f5ccc 475 Pfam PF00232 Glycosyl hydrolase family 1 13 471 1.5E-158 T 10-11-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A4G23_RS09170 9242817cfff898f414d5b511af5f5ccc 475 Gene3D G3DSA:3.20.20.80 14 472 1.4E-161 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS22390 0c6f4123188a7510398ee0f5b3b85714 387 Pfam PF14028 Lantibiotic biosynthesis dehydratase C-term 22 367 5.4E-99 T 10-11-2016 IPR023809 Thiopeptide-type bacteriocin biosynthesis domain A4G23_RS13765 af938603c10c72fa93e036e7af8b8d56 303 SMART SM00382 27 213 7.7E-13 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS13765 af938603c10c72fa93e036e7af8b8d56 303 Pfam PF00005 ABC transporter 20 157 5.9E-26 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS13765 af938603c10c72fa93e036e7af8b8d56 303 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS13765 af938603c10c72fa93e036e7af8b8d56 303 SUPERFAMILY SSF52540 10 210 2.97E-53 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS13765 af938603c10c72fa93e036e7af8b8d56 303 Gene3D G3DSA:3.40.50.300 3 216 7.7E-56 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS10535 c7e9e5e23793bceeaf923fb78651c346 468 Pfam PF07730 Histidine kinase 210 274 5.8E-17 T 10-11-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4G23_RS10535 c7e9e5e23793bceeaf923fb78651c346 468 SUPERFAMILY SSF55874 332 451 8.28E-10 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS06845 8c9e9535da050daf068a2ba430033dc2 356 Gene3D G3DSA:3.40.50.2300 195 332 3.5E-47 T 10-11-2016 A4G23_RS06845 8c9e9535da050daf068a2ba430033dc2 356 SMART SM00354 20 87 2.0E-22 T 10-11-2016 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4G23_RS06845 8c9e9535da050daf068a2ba430033dc2 356 Gene3D G3DSA:3.40.50.2300 70 194 1.3E-34 T 10-11-2016 A4G23_RS06845 8c9e9535da050daf068a2ba430033dc2 356 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 22 32 7.6E-5 T 10-11-2016 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4G23_RS06845 8c9e9535da050daf068a2ba430033dc2 356 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 32 42 7.6E-5 T 10-11-2016 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4G23_RS06845 8c9e9535da050daf068a2ba430033dc2 356 Pfam PF13377 Periplasmic binding protein-like domain 189 351 1.8E-36 T 10-11-2016 A4G23_RS06845 8c9e9535da050daf068a2ba430033dc2 356 Pfam PF00356 Bacterial regulatory proteins, lacI family 23 65 4.2E-15 T 10-11-2016 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4G23_RS06845 8c9e9535da050daf068a2ba430033dc2 356 ProSitePatterns PS00356 LacI-type HTH domain signature. 23 41 - T 10-11-2016 A4G23_RS06845 8c9e9535da050daf068a2ba430033dc2 356 SUPERFAMILY SSF47413 21 67 9.6E-12 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS06845 8c9e9535da050daf068a2ba430033dc2 356 SUPERFAMILY SSF53822 77 354 1.55E-68 T 10-11-2016 IPR028082 Periplasmic binding protein-like I A4G23_RS06845 8c9e9535da050daf068a2ba430033dc2 356 Gene3D G3DSA:1.10.260.40 21 65 1.1E-18 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS03790 01d382722351c0746c57d375b8cffa31 659 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 66 655 32.764 T 10-11-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A4G23_RS03790 01d382722351c0746c57d375b8cffa31 659 Pfam PF03129 Anticodon binding domain 562 654 2.4E-19 T 10-11-2016 IPR004154 Anticodon-binding A4G23_RS03790 01d382722351c0746c57d375b8cffa31 659 SMART SM00863 180 236 2.0E-19 T 10-11-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 A4G23_RS03790 01d382722351c0746c57d375b8cffa31 659 Gene3D G3DSA:3.30.930.10 259 551 8.7E-100 T 10-11-2016 A4G23_RS03790 01d382722351c0746c57d375b8cffa31 659 Gene3D G3DSA:3.30.54.20 132 204 2.7E-9 T 10-11-2016 A4G23_RS03790 01d382722351c0746c57d375b8cffa31 659 PRINTS PR01047 Threonyl-tRNA synthetase signature 555 567 7.4E-49 T 10-11-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A4G23_RS03790 01d382722351c0746c57d375b8cffa31 659 PRINTS PR01047 Threonyl-tRNA synthetase signature 528 541 7.4E-49 T 10-11-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A4G23_RS03790 01d382722351c0746c57d375b8cffa31 659 PRINTS PR01047 Threonyl-tRNA synthetase signature 485 513 7.4E-49 T 10-11-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A4G23_RS03790 01d382722351c0746c57d375b8cffa31 659 PRINTS PR01047 Threonyl-tRNA synthetase signature 348 376 7.4E-49 T 10-11-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A4G23_RS03790 01d382722351c0746c57d375b8cffa31 659 PRINTS PR01047 Threonyl-tRNA synthetase signature 381 404 7.4E-49 T 10-11-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A4G23_RS03790 01d382722351c0746c57d375b8cffa31 659 Gene3D G3DSA:3.30.980.10 205 241 2.7E-42 T 10-11-2016 A4G23_RS03790 01d382722351c0746c57d375b8cffa31 659 Gene3D G3DSA:3.30.980.10 66 129 2.7E-42 T 10-11-2016 A4G23_RS03790 01d382722351c0746c57d375b8cffa31 659 SUPERFAMILY SSF55186 64 258 2.09E-52 T 10-11-2016 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 A4G23_RS03790 01d382722351c0746c57d375b8cffa31 659 Gene3D G3DSA:3.40.50.800 552 655 3.6E-29 T 10-11-2016 IPR004154 Anticodon-binding A4G23_RS03790 01d382722351c0746c57d375b8cffa31 659 SUPERFAMILY SSF55681 260 547 8.76E-86 T 10-11-2016 A4G23_RS03790 01d382722351c0746c57d375b8cffa31 659 SUPERFAMILY SSF52954 550 654 1.81E-27 T 10-11-2016 IPR004154 Anticodon-binding A4G23_RS03790 01d382722351c0746c57d375b8cffa31 659 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 72 652 1.5E-194 T 10-11-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A4G23_RS03790 01d382722351c0746c57d375b8cffa31 659 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 343 550 1.8E-34 T 10-11-2016 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4G23_RS03790 01d382722351c0746c57d375b8cffa31 659 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 190 236 9.3E-13 T 10-11-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 A4G23_RS13055 df04bc4d00fda45ced88bf9947cd19ac 617 Gene3D G3DSA:3.40.50.410 436 581 6.8E-7 T 10-11-2016 IPR002035 von Willebrand factor, type A A4G23_RS13055 df04bc4d00fda45ced88bf9947cd19ac 617 Pfam PF10138 vWA found in TerF C terminus 433 611 9.1E-38 T 10-11-2016 IPR019303 vWA found in TerF C terminus A4G23_RS13055 df04bc4d00fda45ced88bf9947cd19ac 617 SUPERFAMILY SSF53300 435 584 2.07E-13 T 10-11-2016 IPR002035 von Willebrand factor, type A A4G23_RS13055 df04bc4d00fda45ced88bf9947cd19ac 617 SMART SM00327 433 607 5.6E-5 T 10-11-2016 IPR002035 von Willebrand factor, type A A4G23_RS10225 7018bd088473f412c5642134d476e585 419 Pfam PF01979 Amidohydrolase family 91 392 2.1E-21 T 10-11-2016 IPR006680 Amidohydrolase-related GO:0016787 A4G23_RS10225 7018bd088473f412c5642134d476e585 419 SUPERFAMILY SSF51338 23 94 2.09E-14 T 10-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4G23_RS10225 7018bd088473f412c5642134d476e585 419 SUPERFAMILY SSF51338 377 415 2.09E-14 T 10-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4G23_RS10225 7018bd088473f412c5642134d476e585 419 SUPERFAMILY SSF51556 93 375 4.92E-70 T 10-11-2016 IPR032466 Metal-dependent hydrolase A4G23_RS10225 7018bd088473f412c5642134d476e585 419 TIGRFAM TIGR01224 hutI: imidazolonepropionase 57 414 9.3E-108 T 10-11-2016 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A4G23_RS10225 7018bd088473f412c5642134d476e585 419 Gene3D G3DSA:3.20.20.140 101 394 3.7E-45 T 10-11-2016 A4G23_RS10225 7018bd088473f412c5642134d476e585 419 Hamap MF_00372 Imidazolonepropionase [hutI]. 31 417 42.819 T 10-11-2016 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A4G23_RS10225 7018bd088473f412c5642134d476e585 419 Gene3D G3DSA:2.30.40.10 56 100 1.1E-12 T 10-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4G23_RS22800 74cc1c2fa2ed0c76512bd46bb5b0e417 102 SMART SM00418 8 86 1.5E-27 T 10-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4G23_RS22800 74cc1c2fa2ed0c76512bd46bb5b0e417 102 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 57 72 4.5E-13 T 10-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4G23_RS22800 74cc1c2fa2ed0c76512bd46bb5b0e417 102 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 4.5E-13 T 10-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4G23_RS22800 74cc1c2fa2ed0c76512bd46bb5b0e417 102 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 42 57 4.5E-13 T 10-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4G23_RS22800 74cc1c2fa2ed0c76512bd46bb5b0e417 102 Pfam PF01022 Bacterial regulatory protein, arsR family 15 61 2.6E-13 T 10-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4G23_RS22800 74cc1c2fa2ed0c76512bd46bb5b0e417 102 Gene3D G3DSA:1.10.10.10 7 90 1.5E-25 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS22800 74cc1c2fa2ed0c76512bd46bb5b0e417 102 SUPERFAMILY SSF46785 6 91 3.39E-23 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS19840 81d7afc99670615e562acd221853f8d2 565 SUPERFAMILY SSF51445 34 481 2.12E-135 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS19840 81d7afc99670615e562acd221853f8d2 565 Gene3D G3DSA:2.60.40.1180 481 561 1.3E-13 T 10-11-2016 IPR013780 Glycosyl hydrolase, all-beta A4G23_RS19840 81d7afc99670615e562acd221853f8d2 565 Pfam PF16657 Maltogenic Amylase, C-terminal domain 481 558 2.1E-24 T 10-11-2016 IPR032091 Maltogenic Amylase, C-terminal A4G23_RS19840 81d7afc99670615e562acd221853f8d2 565 SMART SM00642 31 433 2.4E-121 T 10-11-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A4G23_RS19840 81d7afc99670615e562acd221853f8d2 565 Gene3D G3DSA:3.90.400.10 123 190 1.8E-25 T 10-11-2016 A4G23_RS19840 81d7afc99670615e562acd221853f8d2 565 Pfam PF00128 Alpha amylase, catalytic domain 46 402 3.0E-78 T 10-11-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A4G23_RS19840 81d7afc99670615e562acd221853f8d2 565 Gene3D G3DSA:3.20.20.80 25 122 1.6E-112 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS19840 81d7afc99670615e562acd221853f8d2 565 Gene3D G3DSA:3.20.20.80 460 474 1.6E-112 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS19840 81d7afc99670615e562acd221853f8d2 565 Gene3D G3DSA:3.20.20.80 198 427 1.6E-112 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS19840 81d7afc99670615e562acd221853f8d2 565 SUPERFAMILY SSF51011 486 561 4.76E-17 T 10-11-2016 A4G23_RS19840 81d7afc99670615e562acd221853f8d2 565 TIGRFAM TIGR02456 treS_nterm: trehalose synthase 23 561 1.2E-303 T 10-11-2016 IPR012810 Trehalose synthase/alpha-amylase, N-terminal GO:0003824|GO:0005975 KEGG: 00500+5.4.99.16|MetaCyc: PWY-2622 A4G23_RS08855 a3d337750cf516b256161bd179a77d28 286 SUPERFAMILY SSF54060 69 280 3.06E-56 T 10-11-2016 A4G23_RS08855 a3d337750cf516b256161bd179a77d28 286 Pfam PF04231 Endonuclease I 71 280 1.9E-37 T 10-11-2016 IPR007346 Endonuclease I GO:0004518 A4G23_RS04085 a2dd8fb39a0ac4f8209d2478652a75e5 272 SUPERFAMILY SSF48179 175 271 4.0E-30 T 10-11-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A4G23_RS04085 a2dd8fb39a0ac4f8209d2478652a75e5 272 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 1 172 1.9E-54 T 10-11-2016 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 A4G23_RS04085 a2dd8fb39a0ac4f8209d2478652a75e5 272 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 175 271 1.5E-32 T 10-11-2016 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 A4G23_RS04085 a2dd8fb39a0ac4f8209d2478652a75e5 272 SUPERFAMILY SSF51735 1 172 9.86E-41 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS04085 a2dd8fb39a0ac4f8209d2478652a75e5 272 PIRSF PIRSF000105 1 272 1.6E-71 T 10-11-2016 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 A4G23_RS04085 a2dd8fb39a0ac4f8209d2478652a75e5 272 Gene3D G3DSA:1.10.1040.10 177 272 3.3E-33 T 10-11-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A4G23_RS04085 a2dd8fb39a0ac4f8209d2478652a75e5 272 Gene3D G3DSA:3.40.50.720 1 176 2.2E-47 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS22805 09e25805347cf72a297d1be6d181ce72 134 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 7 127 1.1E-21 T 10-11-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily A4G23_RS22805 09e25805347cf72a297d1be6d181ce72 134 Gene3D G3DSA:3.40.50.270 3 129 2.4E-41 T 10-11-2016 A4G23_RS22805 09e25805347cf72a297d1be6d181ce72 134 SUPERFAMILY SSF52788 4 128 2.35E-37 T 10-11-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily A4G23_RS22805 09e25805347cf72a297d1be6d181ce72 134 SMART SM00226 5 130 3.5E-46 T 10-11-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily A4G23_RS22295 fc1014510ef739807433bf1783af3284 388 SMART SM00833 258 352 3.2E-31 T 10-11-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal A4G23_RS22295 fc1014510ef739807433bf1783af3284 388 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 7 212 9.0E-58 T 10-11-2016 IPR003495 CobW/HypB/UreG, nucleotide-binding domain A4G23_RS22295 fc1014510ef739807433bf1783af3284 388 Gene3D G3DSA:3.40.50.300 5 231 3.2E-74 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS22295 fc1014510ef739807433bf1783af3284 388 Gene3D G3DSA:3.30.1220.10 246 352 2.4E-14 T 10-11-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal A4G23_RS22295 fc1014510ef739807433bf1783af3284 388 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 258 352 3.6E-23 T 10-11-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal A4G23_RS22295 fc1014510ef739807433bf1783af3284 388 SUPERFAMILY SSF52540 4 319 1.67E-44 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS16390 4373c61d617a90d3a614f2519f517015 303 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 39 188 2.0E-15 T 10-11-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 A4G23_RS16390 4373c61d617a90d3a614f2519f517015 303 Gene3D G3DSA:3.40.80.10 29 202 3.6E-16 T 10-11-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 A4G23_RS16390 4373c61d617a90d3a614f2519f517015 303 SMART SM00644 27 188 3.8E-17 T 10-11-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 A4G23_RS16390 4373c61d617a90d3a614f2519f517015 303 SUPERFAMILY SSF55846 26 202 1.44E-20 T 10-11-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 A4G23_RS06710 60e8e226c8531dffa43451bae67b7894 330 Pfam PF08279 HTH domain 9 60 1.3E-13 T 10-11-2016 IPR013196 Helix-turn-helix, type 11 A4G23_RS06710 60e8e226c8531dffa43451bae67b7894 330 SUPERFAMILY SSF46785 3 60 1.16E-8 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS06710 60e8e226c8531dffa43451bae67b7894 330 Gene3D G3DSA:1.10.10.10 2 63 7.6E-13 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS06710 60e8e226c8531dffa43451bae67b7894 330 Pfam PF13280 WYL domain 140 317 5.0E-41 T 10-11-2016 IPR026881 WYL domain A4G23_RS08635 eda2f376811563de69898ca7fb51ad29 411 SUPERFAMILY SSF116734 12 210 3.11E-33 T 10-11-2016 A4G23_RS08635 eda2f376811563de69898ca7fb51ad29 411 Pfam PF01420 Type I restriction modification DNA specificity domain 80 189 4.3E-10 T 10-11-2016 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 A4G23_RS08635 eda2f376811563de69898ca7fb51ad29 411 Pfam PF01420 Type I restriction modification DNA specificity domain 215 383 8.0E-9 T 10-11-2016 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 A4G23_RS08635 eda2f376811563de69898ca7fb51ad29 411 SUPERFAMILY SSF116734 206 406 6.21E-31 T 10-11-2016 A4G23_RS11740 300a723777a6ad0e5bbfb44f1402b9e1 311 Gene3D G3DSA:3.40.50.10490 14 261 5.2E-79 T 10-11-2016 A4G23_RS11740 300a723777a6ad0e5bbfb44f1402b9e1 311 Pfam PF01380 SIS domain 141 219 3.8E-8 T 10-11-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 A4G23_RS11740 300a723777a6ad0e5bbfb44f1402b9e1 311 SUPERFAMILY SSF53697 16 260 3.64E-64 T 10-11-2016 A4G23_RS11740 300a723777a6ad0e5bbfb44f1402b9e1 311 TIGRFAM TIGR00274 TIGR00274: N-acetylmuramic acid 6-phosphate etherase 18 307 2.9E-109 T 10-11-2016 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 A4G23_RS11740 300a723777a6ad0e5bbfb44f1402b9e1 311 ProSitePatterns PS01272 Glucokinase regulatory protein family signature. 197 214 - T 10-11-2016 IPR005486 Glucokinase regulatory protein, conserved site KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126|Reactome: R-HSA-170822|Reactome: R-HSA-5619107 A4G23_RS11740 300a723777a6ad0e5bbfb44f1402b9e1 311 Hamap MF_00068 N-acetylmuramic acid 6-phosphate etherase [murQ]. 14 307 41.212 T 10-11-2016 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 A4G23_RS06415 875abf32a5662586c6f5cde48bff42af 331 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 296 2.8E-51 T 10-11-2016 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A4G23_RS06415 875abf32a5662586c6f5cde48bff42af 331 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 5 327 6.6E-26 T 10-11-2016 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 A4G23_RS06415 875abf32a5662586c6f5cde48bff42af 331 Gene3D G3DSA:3.40.50.720 118 299 5.7E-56 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS06415 875abf32a5662586c6f5cde48bff42af 331 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 222 238 - T 10-11-2016 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A4G23_RS06415 875abf32a5662586c6f5cde48bff42af 331 Gene3D G3DSA:3.40.50.720 16 117 5.9E-22 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS06415 875abf32a5662586c6f5cde48bff42af 331 SUPERFAMILY SSF51735 101 297 9.87E-53 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS06415 875abf32a5662586c6f5cde48bff42af 331 SUPERFAMILY SSF52283 3 134 1.11E-30 T 10-11-2016 A4G23_RS06415 875abf32a5662586c6f5cde48bff42af 331 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 146 173 - T 10-11-2016 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 A4G23_RS07720 d067fcd4111d3ef78748e21d03816fe0 693 Gene3D G3DSA:3.40.50.740 375 527 2.0E-64 T 10-11-2016 A4G23_RS07720 d067fcd4111d3ef78748e21d03816fe0 693 Gene3D G3DSA:3.40.50.740 61 135 2.0E-64 T 10-11-2016 A4G23_RS07720 d067fcd4111d3ef78748e21d03816fe0 693 Gene3D G3DSA:3.40.50.740 316 340 2.0E-64 T 10-11-2016 A4G23_RS07720 d067fcd4111d3ef78748e21d03816fe0 693 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 6 53 2.3E-12 T 10-11-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS07720 d067fcd4111d3ef78748e21d03816fe0 693 Gene3D G3DSA:3.40.228.10 137 315 3.5E-53 T 10-11-2016 A4G23_RS07720 d067fcd4111d3ef78748e21d03816fe0 693 Gene3D G3DSA:2.40.40.20 530 691 4.8E-60 T 10-11-2016 A4G23_RS07720 d067fcd4111d3ef78748e21d03816fe0 693 Pfam PF00384 Molybdopterin oxidoreductase 61 486 2.4E-71 T 10-11-2016 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS07720 d067fcd4111d3ef78748e21d03816fe0 693 Gene3D G3DSA:2.20.25.90 7 54 3.0E-16 T 10-11-2016 A4G23_RS07720 d067fcd4111d3ef78748e21d03816fe0 693 SUPERFAMILY SSF53706 6 580 4.32E-167 T 10-11-2016 A4G23_RS07720 d067fcd4111d3ef78748e21d03816fe0 693 Pfam PF01568 Molydopterin dinucleotide binding domain 579 685 2.2E-34 T 10-11-2016 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 A4G23_RS07720 d067fcd4111d3ef78748e21d03816fe0 693 SUPERFAMILY SSF50692 539 691 2.94E-50 T 10-11-2016 IPR009010 Aspartate decarboxylase-like domain A4G23_RS07720 d067fcd4111d3ef78748e21d03816fe0 693 SMART SM00926 4 58 2.9E-9 T 10-11-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS09965 84288ccc23f7dc970653958041cc0393 119 Pfam PF06262 Zinicin-like metallopeptidase 56 114 1.6E-6 T 10-11-2016 IPR010428 Zinicin-like metallopeptidase A4G23_RS09965 84288ccc23f7dc970653958041cc0393 119 SUPERFAMILY SSF55486 16 116 8.79E-21 T 10-11-2016 A4G23_RS11645 ed094a99eb0aac766d9ee314c8722c45 415 PIRSF PIRSF001495 1 412 3.9E-133 T 10-11-2016 IPR006396 Glutamate mutase epsilon subunit GO:0019670|GO:0050097 KEGG: 00630+5.4.99.1|KEGG: 00660+5.4.99.1|MetaCyc: PWY-5087|MetaCyc: PWY-5103|MetaCyc: PWY-6728 A4G23_RS11645 ed094a99eb0aac766d9ee314c8722c45 415 Gene3D G3DSA:3.20.20.240 3 351 3.6E-127 T 10-11-2016 IPR014348 Cobalamin (vitamin B12)-dependent enzyme, catalytic subdomain GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A4G23_RS11645 ed094a99eb0aac766d9ee314c8722c45 415 Pfam PF06368 Methylaspartate mutase E chain (MutE) 3 375 6.5E-95 T 10-11-2016 IPR006396 Glutamate mutase epsilon subunit GO:0019670|GO:0050097 KEGG: 00630+5.4.99.1|KEGG: 00660+5.4.99.1|MetaCyc: PWY-5087|MetaCyc: PWY-5103|MetaCyc: PWY-6728 A4G23_RS11645 ed094a99eb0aac766d9ee314c8722c45 415 SUPERFAMILY SSF51703 4 385 1.96E-107 T 10-11-2016 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A4G23_RS07480 7413db81e3b1abec496d11a395e63da7 275 SUPERFAMILY SSF56601 6 265 8.14E-56 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS07480 7413db81e3b1abec496d11a395e63da7 275 Pfam PF00144 Beta-lactamase 13 251 1.1E-38 T 10-11-2016 IPR001466 Beta-lactamase-related A4G23_RS07480 7413db81e3b1abec496d11a395e63da7 275 Gene3D G3DSA:3.40.710.10 6 266 1.6E-49 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS21590 11b8e7723f80b8826411bb2cc872c4cb 448 PRINTS PR00113 Alkaline phosphatase signature 99 114 2.2E-33 T 10-11-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 A4G23_RS21590 11b8e7723f80b8826411bb2cc872c4cb 448 PRINTS PR00113 Alkaline phosphatase signature 44 64 2.2E-33 T 10-11-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 A4G23_RS21590 11b8e7723f80b8826411bb2cc872c4cb 448 PRINTS PR00113 Alkaline phosphatase signature 136 156 2.2E-33 T 10-11-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 A4G23_RS21590 11b8e7723f80b8826411bb2cc872c4cb 448 PRINTS PR00113 Alkaline phosphatase signature 198 208 2.2E-33 T 10-11-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 A4G23_RS21590 11b8e7723f80b8826411bb2cc872c4cb 448 PRINTS PR00113 Alkaline phosphatase signature 296 325 2.2E-33 T 10-11-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 A4G23_RS21590 11b8e7723f80b8826411bb2cc872c4cb 448 SUPERFAMILY SSF53649 34 445 1.16E-110 T 10-11-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 A4G23_RS21590 11b8e7723f80b8826411bb2cc872c4cb 448 Pfam PF00245 Alkaline phosphatase 44 404 2.8E-105 T 10-11-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 A4G23_RS21590 11b8e7723f80b8826411bb2cc872c4cb 448 Gene3D G3DSA:3.40.720.10 36 444 2.3E-113 T 10-11-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 A4G23_RS21590 11b8e7723f80b8826411bb2cc872c4cb 448 ProSitePatterns PS00123 Alkaline phosphatase active site. 99 107 - T 10-11-2016 IPR018299 Alkaline phosphatase, active site GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 A4G23_RS21590 11b8e7723f80b8826411bb2cc872c4cb 448 SMART SM00098 45 448 1.4E-148 T 10-11-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 A4G23_RS05835 a2cd1a44c11e06f2f8ca1f9caedebef5 499 SUPERFAMILY SSF50249 113 191 1.34E-14 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS05835 a2cd1a44c11e06f2f8ca1f9caedebef5 499 SUPERFAMILY SSF50249 280 368 4.08E-26 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS05835 a2cd1a44c11e06f2f8ca1f9caedebef5 499 Gene3D G3DSA:2.40.50.140 287 369 1.9E-29 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS05835 a2cd1a44c11e06f2f8ca1f9caedebef5 499 Gene3D G3DSA:2.40.50.140 205 286 1.8E-30 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS05835 a2cd1a44c11e06f2f8ca1f9caedebef5 499 SMART SM00316 37 108 4.2E-17 T 10-11-2016 IPR022967 RNA-binding domain, S1 A4G23_RS05835 a2cd1a44c11e06f2f8ca1f9caedebef5 499 SMART SM00316 210 280 1.3E-27 T 10-11-2016 IPR022967 RNA-binding domain, S1 A4G23_RS05835 a2cd1a44c11e06f2f8ca1f9caedebef5 499 SMART SM00316 124 191 6.5E-11 T 10-11-2016 IPR022967 RNA-binding domain, S1 A4G23_RS05835 a2cd1a44c11e06f2f8ca1f9caedebef5 499 SMART SM00316 295 366 1.1E-26 T 10-11-2016 IPR022967 RNA-binding domain, S1 A4G23_RS05835 a2cd1a44c11e06f2f8ca1f9caedebef5 499 Pfam PF00575 S1 RNA binding domain 294 366 3.5E-23 T 10-11-2016 IPR003029 S1 domain GO:0003676 A4G23_RS05835 a2cd1a44c11e06f2f8ca1f9caedebef5 499 Pfam PF00575 S1 RNA binding domain 36 108 1.3E-15 T 10-11-2016 IPR003029 S1 domain GO:0003676 A4G23_RS05835 a2cd1a44c11e06f2f8ca1f9caedebef5 499 Pfam PF00575 S1 RNA binding domain 209 280 9.5E-26 T 10-11-2016 IPR003029 S1 domain GO:0003676 A4G23_RS05835 a2cd1a44c11e06f2f8ca1f9caedebef5 499 Pfam PF00575 S1 RNA binding domain 124 191 1.1E-13 T 10-11-2016 IPR003029 S1 domain GO:0003676 A4G23_RS05835 a2cd1a44c11e06f2f8ca1f9caedebef5 499 SUPERFAMILY SSF50249 210 292 3.29E-27 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS05835 a2cd1a44c11e06f2f8ca1f9caedebef5 499 PRINTS PR00681 Ribosomal protein S1 signature 57 71 4.0E-86 T 10-11-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 A4G23_RS05835 a2cd1a44c11e06f2f8ca1f9caedebef5 499 PRINTS PR00681 Ribosomal protein S1 signature 105 124 4.0E-86 T 10-11-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 A4G23_RS05835 a2cd1a44c11e06f2f8ca1f9caedebef5 499 PRINTS PR00681 Ribosomal protein S1 signature 232 253 4.0E-86 T 10-11-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 A4G23_RS05835 a2cd1a44c11e06f2f8ca1f9caedebef5 499 PRINTS PR00681 Ribosomal protein S1 signature 310 329 4.0E-86 T 10-11-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 A4G23_RS05835 a2cd1a44c11e06f2f8ca1f9caedebef5 499 PRINTS PR00681 Ribosomal protein S1 signature 39 57 4.0E-86 T 10-11-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 A4G23_RS05835 a2cd1a44c11e06f2f8ca1f9caedebef5 499 PRINTS PR00681 Ribosomal protein S1 signature 349 367 4.0E-86 T 10-11-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 A4G23_RS05835 a2cd1a44c11e06f2f8ca1f9caedebef5 499 PRINTS PR00681 Ribosomal protein S1 signature 129 145 4.0E-86 T 10-11-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 A4G23_RS05835 a2cd1a44c11e06f2f8ca1f9caedebef5 499 PRINTS PR00681 Ribosomal protein S1 signature 146 163 4.0E-86 T 10-11-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 A4G23_RS05835 a2cd1a44c11e06f2f8ca1f9caedebef5 499 PRINTS PR00681 Ribosomal protein S1 signature 175 195 4.0E-86 T 10-11-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 A4G23_RS05835 a2cd1a44c11e06f2f8ca1f9caedebef5 499 Gene3D G3DSA:2.40.50.140 116 192 7.9E-16 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS05835 a2cd1a44c11e06f2f8ca1f9caedebef5 499 Gene3D G3DSA:2.40.50.140 30 109 3.1E-18 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS05835 a2cd1a44c11e06f2f8ca1f9caedebef5 499 SUPERFAMILY SSF50249 32 131 2.69E-21 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS12665 7c98067ea99d847426ab1cda580939f1 437 Pfam PF07730 Histidine kinase 208 273 1.7E-19 T 10-11-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4G23_RS12665 7c98067ea99d847426ab1cda580939f1 437 SUPERFAMILY SSF55874 322 432 9.04E-13 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS12665 7c98067ea99d847426ab1cda580939f1 437 Gene3D G3DSA:3.30.565.10 337 432 3.7E-5 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS03065 246197b5127ef27aee75c2a4f8f34079 249 SUPERFAMILY SSF46955 36 99 6.41E-13 T 10-11-2016 IPR009061 Putative DNA-binding domain A4G23_RS03065 246197b5127ef27aee75c2a4f8f34079 249 SMART SM00422 21 95 2.1E-16 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS03065 246197b5127ef27aee75c2a4f8f34079 249 Gene3D G3DSA:1.10.1660.10 36 100 7.1E-18 T 10-11-2016 A4G23_RS03065 246197b5127ef27aee75c2a4f8f34079 249 Pfam PF00376 MerR family regulatory protein 23 63 7.1E-11 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS14515 a8d8e8605314371306d4fe77f4364ea0 389 SUPERFAMILY SSF53383 7 384 2.29E-85 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS14515 a8d8e8605314371306d4fe77f4364ea0 389 Pfam PF00155 Aminotransferase class I and II 35 379 2.4E-41 T 10-11-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4G23_RS14515 a8d8e8605314371306d4fe77f4364ea0 389 Gene3D G3DSA:3.40.640.10 49 238 1.3E-46 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS14515 a8d8e8605314371306d4fe77f4364ea0 389 Gene3D G3DSA:3.90.1150.10 239 379 1.4E-42 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS26085 2cb54bdad617477584ab15d07ec7f8e2 390 SMART SM00854 8 292 1.2E-106 T 10-11-2016 IPR019079 Capsule synthesis protein, CapA A4G23_RS26085 2cb54bdad617477584ab15d07ec7f8e2 390 Gene3D G3DSA:3.60.21.30 74 282 3.4E-11 T 10-11-2016 A4G23_RS26085 2cb54bdad617477584ab15d07ec7f8e2 390 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 8 292 8.0E-74 T 10-11-2016 IPR019079 Capsule synthesis protein, CapA A4G23_RS26085 2cb54bdad617477584ab15d07ec7f8e2 390 SUPERFAMILY SSF56300 63 299 2.98E-31 T 10-11-2016 IPR029052 Metallo-dependent phosphatase-like A4G23_RS26085 2cb54bdad617477584ab15d07ec7f8e2 390 SUPERFAMILY SSF56300 8 18 2.98E-31 T 10-11-2016 IPR029052 Metallo-dependent phosphatase-like A4G23_RS12045 b8907e1e835988e2940ac183bff1c245 386 PIRSF PIRSF038994 7 384 2.2E-109 T 10-11-2016 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 A4G23_RS12045 b8907e1e835988e2940ac183bff1c245 386 Gene3D G3DSA:2.30.40.10 6 58 6.6E-12 T 10-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4G23_RS12045 b8907e1e835988e2940ac183bff1c245 386 SUPERFAMILY SSF51556 57 351 4.33E-89 T 10-11-2016 IPR032466 Metal-dependent hydrolase A4G23_RS12045 b8907e1e835988e2940ac183bff1c245 386 Gene3D G3DSA:3.20.20.140 59 331 8.7E-96 T 10-11-2016 A4G23_RS12045 b8907e1e835988e2940ac183bff1c245 386 Pfam PF01979 Amidohydrolase family 54 380 2.5E-31 T 10-11-2016 IPR006680 Amidohydrolase-related GO:0016787 A4G23_RS12045 b8907e1e835988e2940ac183bff1c245 386 SUPERFAMILY SSF51338 7 57 1.11E-13 T 10-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4G23_RS12045 b8907e1e835988e2940ac183bff1c245 386 SUPERFAMILY SSF51338 351 369 1.11E-13 T 10-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4G23_RS12045 b8907e1e835988e2940ac183bff1c245 386 Gene3D G3DSA:2.30.40.10 332 380 3.5E-12 T 10-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4G23_RS12045 b8907e1e835988e2940ac183bff1c245 386 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 35 377 5.4E-79 T 10-11-2016 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 A4G23_RS00745 811788b075ff5aac839288a5c3f59855 882 Gene3D G3DSA:2.60.200.20 19 94 5.7E-18 T 10-11-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 A4G23_RS00745 811788b075ff5aac839288a5c3f59855 882 Pfam PF00498 FHA domain 30 93 1.1E-12 T 10-11-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 A4G23_RS00745 811788b075ff5aac839288a5c3f59855 882 Pfam PF00498 FHA domain 238 302 2.0E-17 T 10-11-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 A4G23_RS00745 811788b075ff5aac839288a5c3f59855 882 SMART SM00382 352 545 9.9E-14 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS00745 811788b075ff5aac839288a5c3f59855 882 Gene3D G3DSA:2.60.200.20 227 304 3.9E-23 T 10-11-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 A4G23_RS00745 811788b075ff5aac839288a5c3f59855 882 SUPERFAMILY SSF52540 317 555 3.79E-58 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS00745 811788b075ff5aac839288a5c3f59855 882 SUPERFAMILY SSF49879 13 95 4.21E-20 T 10-11-2016 IPR008984 SMAD/FHA domain GO:0005515 A4G23_RS00745 811788b075ff5aac839288a5c3f59855 882 Gene3D G3DSA:3.40.50.300 318 550 3.4E-67 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS00745 811788b075ff5aac839288a5c3f59855 882 SMART SM00240 237 288 2.9E-17 T 10-11-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 A4G23_RS00745 811788b075ff5aac839288a5c3f59855 882 SMART SM00240 29 79 4.7E-9 T 10-11-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 A4G23_RS00745 811788b075ff5aac839288a5c3f59855 882 SUPERFAMILY SSF49879 203 326 3.44E-25 T 10-11-2016 IPR008984 SMAD/FHA domain GO:0005515 A4G23_RS00745 811788b075ff5aac839288a5c3f59855 882 Pfam PF01061 ABC-2 type transporter 618 825 3.8E-20 T 10-11-2016 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A4G23_RS00745 811788b075ff5aac839288a5c3f59855 882 ProSitePatterns PS00211 ABC transporters family signature. 462 476 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS00745 811788b075ff5aac839288a5c3f59855 882 Pfam PF00005 ABC transporter 343 490 1.7E-32 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS16610 edd0f07e1d0253f20354ab3f0e2bcde1 216 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 9 207 32.658 T 10-11-2016 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS16610 edd0f07e1d0253f20354ab3f0e2bcde1 216 SUPERFAMILY SSF52166 1 203 4.32E-74 T 10-11-2016 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 A4G23_RS16610 edd0f07e1d0253f20354ab3f0e2bcde1 216 Pfam PF00573 Ribosomal protein L4/L1 family 17 202 5.8E-63 T 10-11-2016 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 A4G23_RS16610 edd0f07e1d0253f20354ab3f0e2bcde1 216 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 17 202 2.3E-69 T 10-11-2016 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS16610 edd0f07e1d0253f20354ab3f0e2bcde1 216 Gene3D G3DSA:3.40.1370.10 58 202 1.1E-49 T 10-11-2016 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 A4G23_RS00675 8d51a96229befddeaa4465e7ac916bc9 305 Gene3D G3DSA:1.10.3720.10 21 292 6.1E-42 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS00675 8d51a96229befddeaa4465e7ac916bc9 305 SUPERFAMILY SSF161098 21 305 1.31E-51 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS00675 8d51a96229befddeaa4465e7ac916bc9 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 130 298 1.5E-12 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS25225 7bbe5bcbb6d50b6817dc5ab9e0f68238 626 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 616 35.651 T 10-11-2016 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453 A4G23_RS25225 7bbe5bcbb6d50b6817dc5ab9e0f68238 626 Gene3D G3DSA:1.20.1270.10 509 579 1.3E-26 T 10-11-2016 IPR029048 Heat shock protein 70kD, C-terminal domain Reactome: R-HSA-3371453 A4G23_RS25225 7bbe5bcbb6d50b6817dc5ab9e0f68238 626 PRINTS PR00301 70kDa heat shock protein signature 31 43 2.0E-72 T 10-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4G23_RS25225 7bbe5bcbb6d50b6817dc5ab9e0f68238 626 PRINTS PR00301 70kDa heat shock protein signature 54 62 2.0E-72 T 10-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4G23_RS25225 7bbe5bcbb6d50b6817dc5ab9e0f68238 626 PRINTS PR00301 70kDa heat shock protein signature 364 383 2.0E-72 T 10-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4G23_RS25225 7bbe5bcbb6d50b6817dc5ab9e0f68238 626 PRINTS PR00301 70kDa heat shock protein signature 178 188 2.0E-72 T 10-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4G23_RS25225 7bbe5bcbb6d50b6817dc5ab9e0f68238 626 PRINTS PR00301 70kDa heat shock protein signature 445 461 2.0E-72 T 10-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4G23_RS25225 7bbe5bcbb6d50b6817dc5ab9e0f68238 626 PRINTS PR00301 70kDa heat shock protein signature 310 326 2.0E-72 T 10-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4G23_RS25225 7bbe5bcbb6d50b6817dc5ab9e0f68238 626 PRINTS PR00301 70kDa heat shock protein signature 341 361 2.0E-72 T 10-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4G23_RS25225 7bbe5bcbb6d50b6817dc5ab9e0f68238 626 PRINTS PR00301 70kDa heat shock protein signature 3 16 2.0E-72 T 10-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4G23_RS25225 7bbe5bcbb6d50b6817dc5ab9e0f68238 626 PRINTS PR00301 70kDa heat shock protein signature 119 139 2.0E-72 T 10-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4G23_RS25225 7bbe5bcbb6d50b6817dc5ab9e0f68238 626 SUPERFAMILY SSF100934 483 580 6.02E-16 T 10-11-2016 IPR029048 Heat shock protein 70kD, C-terminal domain Reactome: R-HSA-3371453 A4G23_RS25225 7bbe5bcbb6d50b6817dc5ab9e0f68238 626 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 4 579 8.7E-273 T 10-11-2016 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453 A4G23_RS25225 7bbe5bcbb6d50b6817dc5ab9e0f68238 626 Pfam PF00012 Hsp70 protein 4 579 4.3E-240 T 10-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4G23_RS25225 7bbe5bcbb6d50b6817dc5ab9e0f68238 626 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 313 327 - T 10-11-2016 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 A4G23_RS25225 7bbe5bcbb6d50b6817dc5ab9e0f68238 626 SUPERFAMILY SSF100920 360 516 1.05E-59 T 10-11-2016 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 A4G23_RS25225 7bbe5bcbb6d50b6817dc5ab9e0f68238 626 Gene3D G3DSA:3.30.420.40 4 38 2.7E-55 T 10-11-2016 A4G23_RS25225 7bbe5bcbb6d50b6817dc5ab9e0f68238 626 Gene3D G3DSA:3.30.420.40 106 170 2.7E-55 T 10-11-2016 A4G23_RS25225 7bbe5bcbb6d50b6817dc5ab9e0f68238 626 Gene3D G3DSA:3.30.30.30 39 105 5.4E-14 T 10-11-2016 A4G23_RS25225 7bbe5bcbb6d50b6817dc5ab9e0f68238 626 SUPERFAMILY SSF53067 167 358 2.53E-65 T 10-11-2016 A4G23_RS25225 7bbe5bcbb6d50b6817dc5ab9e0f68238 626 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 10-11-2016 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 A4G23_RS25225 7bbe5bcbb6d50b6817dc5ab9e0f68238 626 Gene3D G3DSA:3.30.420.40 295 337 2.5E-34 T 10-11-2016 A4G23_RS25225 7bbe5bcbb6d50b6817dc5ab9e0f68238 626 Gene3D G3DSA:3.30.420.40 171 205 2.5E-34 T 10-11-2016 A4G23_RS25225 7bbe5bcbb6d50b6817dc5ab9e0f68238 626 Gene3D G3DSA:2.60.34.10 366 508 1.8E-72 T 10-11-2016 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 A4G23_RS25225 7bbe5bcbb6d50b6817dc5ab9e0f68238 626 Gene3D G3DSA:3.90.640.10 206 291 4.9E-29 T 10-11-2016 A4G23_RS25225 7bbe5bcbb6d50b6817dc5ab9e0f68238 626 SUPERFAMILY SSF53067 3 164 2.41E-54 T 10-11-2016 A4G23_RS25225 7bbe5bcbb6d50b6817dc5ab9e0f68238 626 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 172 185 - T 10-11-2016 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 A4G23_RS26960 1dc13d0f02711bcde843d4f3c14b9190 234 Gene3D G3DSA:3.20.20.370 32 227 1.1E-43 T 10-11-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 A4G23_RS26960 1dc13d0f02711bcde843d4f3c14b9190 234 SUPERFAMILY SSF88713 29 227 5.12E-47 T 10-11-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A4G23_RS26960 1dc13d0f02711bcde843d4f3c14b9190 234 Pfam PF01522 Polysaccharide deacetylase 34 153 3.0E-24 T 10-11-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 A4G23_RS16765 b194f77cd358ffd321560ccf842a7d8d 147 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 7 141 1.0E-60 T 10-11-2016 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS16765 b194f77cd358ffd321560ccf842a7d8d 147 ProSitePatterns PS00783 Ribosomal protein L13 signature. 105 127 - T 10-11-2016 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 A4G23_RS16765 b194f77cd358ffd321560ccf842a7d8d 147 Gene3D G3DSA:3.90.1180.10 3 141 6.4E-64 T 10-11-2016 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 A4G23_RS16765 b194f77cd358ffd321560ccf842a7d8d 147 SUPERFAMILY SSF52161 4 144 2.09E-60 T 10-11-2016 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 A4G23_RS16765 b194f77cd358ffd321560ccf842a7d8d 147 PIRSF PIRSF002181 2 147 3.1E-48 T 10-11-2016 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 A4G23_RS16765 b194f77cd358ffd321560ccf842a7d8d 147 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 146 28.279 T 10-11-2016 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 A4G23_RS16765 b194f77cd358ffd321560ccf842a7d8d 147 Pfam PF00572 Ribosomal protein L13 14 137 2.1E-57 T 10-11-2016 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 A4G23_RS23470 07aaafde09b1b798fc32ed491f30dc03 366 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 4 284 2.9E-62 T 10-11-2016 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 A4G23_RS23470 07aaafde09b1b798fc32ed491f30dc03 366 TIGRFAM TIGR02050 gshA_cyan_rel: carboxylate-amine ligase, YbdK family 4 289 7.2E-92 T 10-11-2016 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 A4G23_RS23470 07aaafde09b1b798fc32ed491f30dc03 366 Hamap MF_01609 Glutamate--cysteine ligase [gshA]. 1 366 73.127 T 10-11-2016 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 A4G23_RS23470 07aaafde09b1b798fc32ed491f30dc03 366 SUPERFAMILY SSF55931 3 361 2.55E-89 T 10-11-2016 A4G23_RS19750 44249ed5feccc38beda023d1a4f324fe 216 Gene3D G3DSA:1.10.357.10 68 212 2.2E-37 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS19750 44249ed5feccc38beda023d1a4f324fe 216 Pfam PF00440 Bacterial regulatory proteins, tetR family 29 73 2.1E-12 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS19750 44249ed5feccc38beda023d1a4f324fe 216 Pfam PF16859 Bacterial transcriptional repressor C-terminal 85 205 1.4E-17 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS19750 44249ed5feccc38beda023d1a4f324fe 216 SUPERFAMILY SSF48498 89 211 2.35E-14 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS19750 44249ed5feccc38beda023d1a4f324fe 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 50 73 1.2E-5 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS19750 44249ed5feccc38beda023d1a4f324fe 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 42 1.2E-5 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS19750 44249ed5feccc38beda023d1a4f324fe 216 Gene3D G3DSA:1.10.10.60 19 66 4.5E-21 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS19750 44249ed5feccc38beda023d1a4f324fe 216 SUPERFAMILY SSF46689 19 83 1.8E-14 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS26115 485a73225d2550134217641336b16ad9 255 Gene3D G3DSA:3.40.50.10320 24 233 3.0E-50 T 10-11-2016 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 A4G23_RS26115 485a73225d2550134217641336b16ad9 255 Pfam PF02585 GlcNAc-PI de-N-acetylase 28 156 2.9E-27 T 10-11-2016 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 A4G23_RS26115 485a73225d2550134217641336b16ad9 255 SUPERFAMILY SSF102588 24 217 1.83E-44 T 10-11-2016 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 A4G23_RS25165 18eed67c81938571a705ecf3b57ea977 240 Pfam PF07510 Protein of unknown function (DUF1524) 116 232 8.0E-8 T 10-11-2016 IPR011089 Domain of unknown function DUF1524 A4G23_RS21500 089449f58a7828bee219786262eee8b8 217 SUPERFAMILY SSF52172 2 172 3.37E-34 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS21500 089449f58a7828bee219786262eee8b8 217 SMART SM00448 1 112 1.7E-32 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS21500 089449f58a7828bee219786262eee8b8 217 Pfam PF00072 Response regulator receiver domain 3 113 8.1E-26 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS21500 089449f58a7828bee219786262eee8b8 217 Gene3D G3DSA:1.10.10.10 125 217 4.7E-28 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS21500 089449f58a7828bee219786262eee8b8 217 SMART SM00862 145 217 3.4E-23 T 10-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4G23_RS21500 089449f58a7828bee219786262eee8b8 217 Gene3D G3DSA:3.40.50.2300 2 119 8.1E-33 T 10-11-2016 A4G23_RS21500 089449f58a7828bee219786262eee8b8 217 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 217 8.1E-23 T 10-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4G23_RS25420 40670e922eada5300681ec28d6cb4603 483 Gene3D G3DSA:2.20.140.10 11 78 1.3E-22 T 10-11-2016 IPR008893 WGR domain A4G23_RS25420 40670e922eada5300681ec28d6cb4603 483 SUPERFAMILY SSF142921 10 77 3.66E-9 T 10-11-2016 IPR008893 WGR domain A4G23_RS25420 40670e922eada5300681ec28d6cb4603 483 SUPERFAMILY SSF50998 105 374 4.91E-23 T 10-11-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily A4G23_RS25420 40670e922eada5300681ec28d6cb4603 483 SMART SM00773 8 81 6.6E-21 T 10-11-2016 IPR008893 WGR domain A4G23_RS25420 40670e922eada5300681ec28d6cb4603 483 Gene3D G3DSA:2.140.10.10 105 376 7.5E-20 T 10-11-2016 IPR027295 Quinoprotein alcohol dehydrogenase-like domain A4G23_RS25420 40670e922eada5300681ec28d6cb4603 483 Pfam PF13570 PQQ-like domain 336 373 9.1E-5 T 10-11-2016 IPR025666 Pyrrolo-quinoline quinone-like domain A4G23_RS25420 40670e922eada5300681ec28d6cb4603 483 Pfam PF05406 WGR domain 10 77 1.1E-16 T 10-11-2016 IPR008893 WGR domain A4G23_RS25885 9df248159240b85ee55dd1826edd61cd 271 SUPERFAMILY SSF56235 2 251 5.4E-18 T 10-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal A4G23_RS25885 9df248159240b85ee55dd1826edd61cd 271 TIGRFAM TIGR03442 TIGR03442: ergothioneine biosynthesis protein EgtC 1 246 3.8E-86 T 10-11-2016 IPR017808 Ergothioneine biosynthesis protein EgtC GO:0052699 A4G23_RS25885 9df248159240b85ee55dd1826edd61cd 271 Pfam PF13522 Glutamine amidotransferase domain 71 217 1.5E-17 T 10-11-2016 A4G23_RS25885 9df248159240b85ee55dd1826edd61cd 271 Gene3D G3DSA:3.60.20.10 1 246 1.0E-40 T 10-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal A4G23_RS25885 9df248159240b85ee55dd1826edd61cd 271 Hamap MF_02036 Gamma-glutamyl-hercynylcysteine sulfoxide hydrolase [egtC]. 1 247 40.917 T 10-11-2016 IPR032889 Gamma-glutamyl-hercynylcysteine sulfoxide hydrolase, Actinobacteria GO:0016811|GO:0052699 KEGG: 00311+3.5.1.11|KEGG: 00340+3.5.1.118|MetaCyc: PWY-7255 A4G23_RS06645 168f60a83090704caccb3b82366b9006 637 Gene3D G3DSA:1.20.1560.10 24 326 1.0E-61 T 10-11-2016 A4G23_RS06645 168f60a83090704caccb3b82366b9006 637 SUPERFAMILY SSF52540 393 632 3.62E-78 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS06645 168f60a83090704caccb3b82366b9006 637 ProSitePatterns PS00211 ABC transporters family signature. 533 547 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS06645 168f60a83090704caccb3b82366b9006 637 Gene3D G3DSA:3.40.50.300 395 619 5.2E-70 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS06645 168f60a83090704caccb3b82366b9006 637 SMART SM00382 421 607 6.2E-14 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS06645 168f60a83090704caccb3b82366b9006 637 Pfam PF00005 ABC transporter 414 561 2.8E-28 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS06645 168f60a83090704caccb3b82366b9006 637 SUPERFAMILY SSF90123 23 326 2.75E-60 T 10-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A4G23_RS06645 168f60a83090704caccb3b82366b9006 637 Pfam PF00664 ABC transporter transmembrane region 37 304 4.8E-40 T 10-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A4G23_RS17615 a0c7e954235008cfce507c2aad7cf3f6 325 Gene3D G3DSA:1.10.10.10 128 188 8.2E-13 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS17615 a0c7e954235008cfce507c2aad7cf3f6 325 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 9 187 2.2E-27 T 10-11-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS17615 a0c7e954235008cfce507c2aad7cf3f6 325 Gene3D G3DSA:1.10.1740.10 7 92 4.1E-26 T 10-11-2016 A4G23_RS17615 a0c7e954235008cfce507c2aad7cf3f6 325 Pfam PF08281 Sigma-70, region 4 134 186 2.6E-13 T 10-11-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS17615 a0c7e954235008cfce507c2aad7cf3f6 325 Gene3D G3DSA:3.10.450.50 203 317 7.4E-20 T 10-11-2016 IPR032710 NTF2-like domain A4G23_RS17615 a0c7e954235008cfce507c2aad7cf3f6 325 SUPERFAMILY SSF88946 7 93 9.68E-24 T 10-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS17615 a0c7e954235008cfce507c2aad7cf3f6 325 Pfam PF04542 Sigma-70 region 2 15 80 8.9E-21 T 10-11-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS17615 a0c7e954235008cfce507c2aad7cf3f6 325 SUPERFAMILY SSF88659 129 187 9.35E-11 T 10-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS17615 a0c7e954235008cfce507c2aad7cf3f6 325 Pfam PF12680 SnoaL-like domain 209 301 3.4E-8 T 10-11-2016 IPR009959 Polyketide cyclase SnoaL-like domain A4G23_RS17615 a0c7e954235008cfce507c2aad7cf3f6 325 TIGRFAM TIGR02960 SigX5: RNA polymerase sigma-70 factor, TIGR02960 family 7 319 1.1E-138 T 10-11-2016 IPR014305 RNA polymerase sigma-G type, actinobacteria A4G23_RS17615 a0c7e954235008cfce507c2aad7cf3f6 325 SUPERFAMILY SSF54427 202 315 4.78E-20 T 10-11-2016 IPR032710 NTF2-like domain A4G23_RS11585 c99e9f7487276870b3799775e2c599fa 372 Gene3D G3DSA:3.90.1150.10 268 369 1.5E-4 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS11585 c99e9f7487276870b3799775e2c599fa 372 Gene3D G3DSA:3.40.640.10 20 266 3.1E-52 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS11585 c99e9f7487276870b3799775e2c599fa 372 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 5 372 23.54 T 10-11-2016 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 A4G23_RS11585 c99e9f7487276870b3799775e2c599fa 372 SUPERFAMILY SSF53383 12 370 3.23E-77 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS11585 c99e9f7487276870b3799775e2c599fa 372 TIGRFAM TIGR01366 serC_3: putative phosphoserine aminotransferase 11 371 8.5E-213 T 10-11-2016 IPR006272 Phosphoserine aminotransferase, Mycobacterial-type GO:0004648|GO:0006564|GO:0009058 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52 A4G23_RS11585 c99e9f7487276870b3799775e2c599fa 372 Pfam PF00266 Aminotransferase class-V 18 331 1.2E-18 T 10-11-2016 IPR000192 Aminotransferase class V domain A4G23_RS11585 c99e9f7487276870b3799775e2c599fa 372 PIRSF PIRSF000525 1 371 1.0E-75 T 10-11-2016 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 A4G23_RS19010 75006e6e5559a28c92cdc62299842b40 427 Pfam PF13416 Bacterial extracellular solute-binding protein 60 364 3.7E-36 T 10-11-2016 A4G23_RS19010 75006e6e5559a28c92cdc62299842b40 427 Gene3D G3DSA:3.40.190.10 37 167 5.2E-20 T 10-11-2016 A4G23_RS19010 75006e6e5559a28c92cdc62299842b40 427 Gene3D G3DSA:3.40.190.10 168 356 6.8E-36 T 10-11-2016 A4G23_RS19010 75006e6e5559a28c92cdc62299842b40 427 SUPERFAMILY SSF53850 20 424 2.48E-66 T 10-11-2016 A4G23_RS24040 9255f6258a5bc586ec91af6298b7efd5 949 Pfam PF03704 Bacterial transcriptional activator domain 95 237 1.9E-38 T 10-11-2016 IPR005158 Bacterial transcriptional activator domain A4G23_RS24040 9255f6258a5bc586ec91af6298b7efd5 949 SUPERFAMILY SSF46894 3 88 2.3E-11 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS24040 9255f6258a5bc586ec91af6298b7efd5 949 SUPERFAMILY SSF48452 804 925 6.13E-8 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS24040 9255f6258a5bc586ec91af6298b7efd5 949 Pfam PF00486 Transcriptional regulatory protein, C terminal 24 77 7.8E-7 T 10-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4G23_RS24040 9255f6258a5bc586ec91af6298b7efd5 949 Gene3D G3DSA:1.25.40.10 685 941 2.4E-12 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS24040 9255f6258a5bc586ec91af6298b7efd5 949 Gene3D G3DSA:1.10.10.10 15 78 2.4E-6 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS24040 9255f6258a5bc586ec91af6298b7efd5 949 SMART SM01043 95 237 1.3E-45 T 10-11-2016 IPR005158 Bacterial transcriptional activator domain A4G23_RS24040 9255f6258a5bc586ec91af6298b7efd5 949 SUPERFAMILY SSF48452 91 260 1.19E-31 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS24040 9255f6258a5bc586ec91af6298b7efd5 949 SUPERFAMILY SSF52540 250 535 5.88E-23 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS24040 9255f6258a5bc586ec91af6298b7efd5 949 SMART SM00862 16 88 1.9E-8 T 10-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4G23_RS24040 9255f6258a5bc586ec91af6298b7efd5 949 PRINTS PR00364 Disease resistance protein signature 468 482 9.1E-8 T 10-11-2016 A4G23_RS24040 9255f6258a5bc586ec91af6298b7efd5 949 PRINTS PR00364 Disease resistance protein signature 363 377 9.1E-8 T 10-11-2016 A4G23_RS24040 9255f6258a5bc586ec91af6298b7efd5 949 PRINTS PR00364 Disease resistance protein signature 286 301 9.1E-8 T 10-11-2016 A4G23_RS24040 9255f6258a5bc586ec91af6298b7efd5 949 Pfam PF00931 NB-ARC domain 270 375 1.9E-6 T 10-11-2016 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6803207 A4G23_RS24040 9255f6258a5bc586ec91af6298b7efd5 949 Gene3D G3DSA:3.40.50.300 265 383 1.4E-4 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS03920 8c8723c073d981f60e1aed1aecdf9eee 209 Pfam PF13302 Acetyltransferase (GNAT) domain 18 158 2.7E-26 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS03920 8c8723c073d981f60e1aed1aecdf9eee 209 Gene3D G3DSA:3.40.630.30 12 197 1.0E-47 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS03920 8c8723c073d981f60e1aed1aecdf9eee 209 SUPERFAMILY SSF55729 11 179 9.61E-37 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS18770 11503b0502c0b50544ebbc5b8cd4d881 85 Pfam PF00462 Glutaredoxin 5 60 1.8E-13 T 10-11-2016 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 A4G23_RS18770 11503b0502c0b50544ebbc5b8cd4d881 85 Gene3D G3DSA:3.40.30.10 4 80 7.7E-20 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS18770 11503b0502c0b50544ebbc5b8cd4d881 85 SUPERFAMILY SSF52833 4 67 1.71E-15 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS18770 11503b0502c0b50544ebbc5b8cd4d881 85 ProSitePatterns PS00194 Thioredoxin family active site. 5 23 - T 10-11-2016 IPR017937 Thioredoxin, conserved site GO:0045454 A4G23_RS18770 11503b0502c0b50544ebbc5b8cd4d881 85 TIGRFAM TIGR02200 GlrX_actino: glutaredoxin-like protein 4 84 5.9E-27 T 10-11-2016 IPR011915 Glutaredoxin-like protein, actinobacteria A4G23_RS10845 fc0bfdf419be0da2724cf0453c4fa256 144 SUPERFAMILY SSF54427 4 138 1.37E-33 T 10-11-2016 IPR032710 NTF2-like domain A4G23_RS10845 fc0bfdf419be0da2724cf0453c4fa256 144 Pfam PF12680 SnoaL-like domain 9 121 2.3E-26 T 10-11-2016 IPR009959 Polyketide cyclase SnoaL-like domain A4G23_RS10845 fc0bfdf419be0da2724cf0453c4fa256 144 Gene3D G3DSA:3.10.450.50 4 141 1.6E-32 T 10-11-2016 IPR032710 NTF2-like domain A4G23_RS15010 d8a43765e0d2bb904c4bec5f23e806ef 118 Pfam PF01638 HxlR-like helix-turn-helix 20 107 2.8E-33 T 10-11-2016 IPR002577 Helix-turn-helix, HxlR type A4G23_RS15010 d8a43765e0d2bb904c4bec5f23e806ef 118 Gene3D G3DSA:1.10.10.10 10 114 1.0E-42 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS15010 d8a43765e0d2bb904c4bec5f23e806ef 118 SUPERFAMILY SSF46785 9 114 2.04E-34 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS26235 e6a8cfac775cd64a8f87130cc6b23a4b 834 Gene3D G3DSA:3.40.228.10 175 359 1.6E-53 T 10-11-2016 A4G23_RS26235 e6a8cfac775cd64a8f87130cc6b23a4b 834 Pfam PF01568 Molydopterin dinucleotide binding domain 652 771 1.5E-24 T 10-11-2016 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 A4G23_RS26235 e6a8cfac775cd64a8f87130cc6b23a4b 834 Gene3D G3DSA:3.40.50.740 360 580 4.1E-81 T 10-11-2016 A4G23_RS26235 e6a8cfac775cd64a8f87130cc6b23a4b 834 Gene3D G3DSA:3.40.50.740 99 174 4.1E-81 T 10-11-2016 A4G23_RS26235 e6a8cfac775cd64a8f87130cc6b23a4b 834 Gene3D G3DSA:2.40.40.20 581 775 4.8E-42 T 10-11-2016 A4G23_RS26235 e6a8cfac775cd64a8f87130cc6b23a4b 834 SUPERFAMILY SSF50692 627 774 1.99E-36 T 10-11-2016 IPR009010 Aspartate decarboxylase-like domain A4G23_RS26235 e6a8cfac775cd64a8f87130cc6b23a4b 834 Gene3D G3DSA:2.20.25.90 57 98 9.7E-6 T 10-11-2016 A4G23_RS26235 e6a8cfac775cd64a8f87130cc6b23a4b 834 SUPERFAMILY SSF53706 43 597 4.97E-160 T 10-11-2016 A4G23_RS26235 e6a8cfac775cd64a8f87130cc6b23a4b 834 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 473 490 - T 10-11-2016 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 A4G23_RS26235 e6a8cfac775cd64a8f87130cc6b23a4b 834 Pfam PF00384 Molybdopterin oxidoreductase 99 522 2.7E-70 T 10-11-2016 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS08640 ce7510dc53439b94971a794bc32262ec 1032 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 8 196 1.3E-31 T 10-11-2016 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 A4G23_RS08640 ce7510dc53439b94971a794bc32262ec 1032 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 24 699 5.7E-164 T 10-11-2016 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 A4G23_RS08640 ce7510dc53439b94971a794bc32262ec 1032 SMART SM00487 244 457 2.8E-10 T 10-11-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4G23_RS08640 ce7510dc53439b94971a794bc32262ec 1032 Pfam PF04851 Type III restriction enzyme, res subunit 250 420 9.9E-17 T 10-11-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 A4G23_RS08640 ce7510dc53439b94971a794bc32262ec 1032 SUPERFAMILY SSF52540 212 442 1.17E-24 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS08640 ce7510dc53439b94971a794bc32262ec 1032 Gene3D G3DSA:3.40.50.300 245 428 1.2E-18 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS01605 614a39a4dac99a156dd242e49d839a7d 400 Pfam PF05139 Erythromycin esterase 52 396 5.7E-69 T 10-11-2016 IPR007815 Erythromycin esterase GO:0046677 A4G23_RS01605 614a39a4dac99a156dd242e49d839a7d 400 PIRSF PIRSF036794 1 399 2.9E-89 T 10-11-2016 IPR014622 Uncharacterised conserved protein UCP036794, erythromycin esterase-type A4G23_RS01605 614a39a4dac99a156dd242e49d839a7d 400 SUPERFAMILY SSF159501 21 396 1.07E-84 T 10-11-2016 A4G23_RS01605 614a39a4dac99a156dd242e49d839a7d 400 Gene3D G3DSA:3.30.1870.10 54 127 1.9E-17 T 10-11-2016 A4G23_RS01605 614a39a4dac99a156dd242e49d839a7d 400 Gene3D G3DSA:3.40.1660.10 278 370 2.0E-11 T 10-11-2016 A4G23_RS01605 614a39a4dac99a156dd242e49d839a7d 400 Gene3D G3DSA:3.40.1660.10 24 53 2.0E-11 T 10-11-2016 A4G23_RS20150 624af78c7ac84f486f9b3b261dee3751 543 SUPERFAMILY SSF53720 8 527 1.7E-123 T 10-11-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A4G23_RS20150 624af78c7ac84f486f9b3b261dee3751 543 TIGRFAM TIGR01236 D1pyr5carbox1: 1-pyrroline-5-carboxylate dehydrogenase 12 542 1.5E-242 T 10-11-2016 IPR005931 Delta-1-pyrroline-5-carboxylate dehydrogenase GO:0003842|GO:0006537|GO:0006561 KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853|Reactome: R-HSA-70688 A4G23_RS20150 624af78c7ac84f486f9b3b261dee3751 543 Gene3D G3DSA:3.40.309.10 303 501 6.2E-43 T 10-11-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 A4G23_RS20150 624af78c7ac84f486f9b3b261dee3751 543 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 321 332 - T 10-11-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 A4G23_RS20150 624af78c7ac84f486f9b3b261dee3751 543 Gene3D G3DSA:3.40.605.10 41 302 2.7E-63 T 10-11-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A4G23_RS20150 624af78c7ac84f486f9b3b261dee3751 543 Pfam PF00171 Aldehyde dehydrogenase family 55 526 1.4E-103 T 10-11-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A4G23_RS14975 5c31ef25fbfdafea40ea986cb42c3212 1081 SUPERFAMILY SSF103473 289 475 7.46E-10 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS14975 5c31ef25fbfdafea40ea986cb42c3212 1081 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 513 702 4.9E-50 T 10-11-2016 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 A4G23_RS14975 5c31ef25fbfdafea40ea986cb42c3212 1081 ProSitePatterns PS01331 Thymidylate kinase signature. 603 615 - T 10-11-2016 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 A4G23_RS14975 5c31ef25fbfdafea40ea986cb42c3212 1081 SUPERFAMILY SSF52540 512 713 7.54E-54 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS14975 5c31ef25fbfdafea40ea986cb42c3212 1081 Hamap MF_00165 Thymidylate kinase [tmk]. 514 713 30.72 T 10-11-2016 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 A4G23_RS14975 5c31ef25fbfdafea40ea986cb42c3212 1081 Gene3D G3DSA:3.40.50.300 513 713 7.7E-74 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS14975 5c31ef25fbfdafea40ea986cb42c3212 1081 Pfam PF02223 Thymidylate kinase 518 702 2.1E-46 T 10-11-2016 A4G23_RS14975 5c31ef25fbfdafea40ea986cb42c3212 1081 Gene3D G3DSA:1.20.1250.20 295 481 2.1E-11 T 10-11-2016 A4G23_RS14660 1f3f1c1dc22defee87cd3d30a696ee68 278 SMART SM00530 20 75 0.0036 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS14660 1f3f1c1dc22defee87cd3d30a696ee68 278 SUPERFAMILY SSF47413 7 78 3.66E-9 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS14660 1f3f1c1dc22defee87cd3d30a696ee68 278 Pfam PF13560 Helix-turn-helix domain 22 68 2.1E-6 T 10-11-2016 A4G23_RS14660 1f3f1c1dc22defee87cd3d30a696ee68 278 Gene3D G3DSA:1.10.260.40 15 69 4.1E-10 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS19320 d66dc44b9c132aa737f89ce61a1ace51 211 SMART SM00421 146 203 1.5E-24 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS19320 d66dc44b9c132aa737f89ce61a1ace51 211 SUPERFAMILY SSF52172 5 140 1.11E-29 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS19320 d66dc44b9c132aa737f89ce61a1ace51 211 SMART SM00448 6 120 1.9E-29 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS19320 d66dc44b9c132aa737f89ce61a1ace51 211 SUPERFAMILY SSF46894 138 209 5.44E-22 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS19320 d66dc44b9c132aa737f89ce61a1ace51 211 ProSitePatterns PS00622 LuxR-type HTH domain signature. 163 190 - T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS19320 d66dc44b9c132aa737f89ce61a1ace51 211 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 202 9.2E-19 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS19320 d66dc44b9c132aa737f89ce61a1ace51 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 3.7E-13 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS19320 d66dc44b9c132aa737f89ce61a1ace51 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 3.7E-13 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS19320 d66dc44b9c132aa737f89ce61a1ace51 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 3.7E-13 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS19320 d66dc44b9c132aa737f89ce61a1ace51 211 Gene3D G3DSA:3.40.50.2300 4 151 4.8E-34 T 10-11-2016 A4G23_RS19320 d66dc44b9c132aa737f89ce61a1ace51 211 Gene3D G3DSA:1.10.10.10 152 209 5.3E-26 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS19320 d66dc44b9c132aa737f89ce61a1ace51 211 Pfam PF00072 Response regulator receiver domain 9 120 1.7E-24 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS22945 db57f2df3167694eb650ba5ca5115536 354 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 16 350 1.6E-127 T 10-11-2016 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 A4G23_RS22945 db57f2df3167694eb650ba5ca5115536 354 SUPERFAMILY SSF51726 14 350 4.84E-105 T 10-11-2016 A4G23_RS22945 db57f2df3167694eb650ba5ca5115536 354 Gene3D G3DSA:3.20.20.210 14 350 1.6E-142 T 10-11-2016 A4G23_RS22945 db57f2df3167694eb650ba5ca5115536 354 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 149 165 - T 10-11-2016 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 A4G23_RS22945 db57f2df3167694eb650ba5ca5115536 354 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 32 41 - T 10-11-2016 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 A4G23_RS22945 db57f2df3167694eb650ba5ca5115536 354 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 19 349 1.4E-121 T 10-11-2016 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 A4G23_RS22945 db57f2df3167694eb650ba5ca5115536 354 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 16 352 47.473 T 10-11-2016 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 A4G23_RS18920 b252aa63305901ede3a8686683f3e8ed 271 Pfam PF02586 SOS response associated peptidase (SRAP) 1 251 5.0E-67 T 10-11-2016 IPR003738 SOS response associated peptidase (SRAP) A4G23_RS18920 b252aa63305901ede3a8686683f3e8ed 271 Gene3D G3DSA:3.90.1680.10 1 261 9.6E-76 T 10-11-2016 IPR003738 SOS response associated peptidase (SRAP) A4G23_RS18920 b252aa63305901ede3a8686683f3e8ed 271 SUPERFAMILY SSF143081 2 260 4.58E-65 T 10-11-2016 IPR003738 SOS response associated peptidase (SRAP) A4G23_RS01265 2f47426d0afd44eded0eb879c1f14168 403 Gene3D G3DSA:3.40.250.10 291 393 2.6E-25 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS01265 2f47426d0afd44eded0eb879c1f14168 403 SMART SM00849 13 180 2.8E-14 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS01265 2f47426d0afd44eded0eb879c1f14168 403 SUPERFAMILY SSF56281 11 183 3.5E-36 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS01265 2f47426d0afd44eded0eb879c1f14168 403 SUPERFAMILY SSF52821 291 394 3.14E-27 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS01265 2f47426d0afd44eded0eb879c1f14168 403 Pfam PF00753 Metallo-beta-lactamase superfamily 21 180 4.4E-6 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS01265 2f47426d0afd44eded0eb879c1f14168 403 Pfam PF00581 Rhodanese-like domain 308 387 1.5E-10 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS01265 2f47426d0afd44eded0eb879c1f14168 403 SMART SM00450 294 391 3.2E-20 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS01265 2f47426d0afd44eded0eb879c1f14168 403 Gene3D G3DSA:3.60.15.10 12 227 1.9E-41 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS20700 92fdb4debe861faf38c1da257db2a644 382 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 40 361 2.9E-107 T 10-11-2016 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 A4G23_RS20700 92fdb4debe861faf38c1da257db2a644 382 Pfam PF08402 TOBE domain 283 363 5.4E-15 T 10-11-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 A4G23_RS20700 92fdb4debe861faf38c1da257db2a644 382 SUPERFAMILY SSF50331 241 363 1.43E-15 T 10-11-2016 IPR008995 Molybdate/tungstate binding, C-terminal A4G23_RS20700 92fdb4debe861faf38c1da257db2a644 382 SMART SM00382 34 215 1.0E-13 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS20700 92fdb4debe861faf38c1da257db2a644 382 SUPERFAMILY SSF52540 10 245 3.33E-86 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS20700 92fdb4debe861faf38c1da257db2a644 382 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS20700 92fdb4debe861faf38c1da257db2a644 382 Pfam PF00005 ABC transporter 26 165 2.6E-32 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS20700 92fdb4debe861faf38c1da257db2a644 382 Gene3D G3DSA:3.40.50.300 10 238 1.4E-75 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS26745 570425dd7e4b1bc8d63c17263c194860 638 SUPERFAMILY SSF56322 100 391 1.57E-64 T 10-11-2016 IPR005801 ADC synthase GO:0009058 A4G23_RS26745 570425dd7e4b1bc8d63c17263c194860 638 Gene3D G3DSA:3.40.50.880 448 630 3.7E-27 T 10-11-2016 IPR029062 Class I glutamine amidotransferase-like A4G23_RS26745 570425dd7e4b1bc8d63c17263c194860 638 PRINTS PR00096 Glutamine amidotransferase superfamily signature 609 622 5.7E-8 T 10-11-2016 A4G23_RS26745 570425dd7e4b1bc8d63c17263c194860 638 PRINTS PR00096 Glutamine amidotransferase superfamily signature 523 534 5.7E-8 T 10-11-2016 A4G23_RS26745 570425dd7e4b1bc8d63c17263c194860 638 PRINTS PR00096 Glutamine amidotransferase superfamily signature 490 499 5.7E-8 T 10-11-2016 A4G23_RS26745 570425dd7e4b1bc8d63c17263c194860 638 PRINTS PR00097 Anthranilate synthase component II signature 523 534 1.7E-6 T 10-11-2016 A4G23_RS26745 570425dd7e4b1bc8d63c17263c194860 638 PRINTS PR00097 Anthranilate synthase component II signature 609 622 1.7E-6 T 10-11-2016 A4G23_RS26745 570425dd7e4b1bc8d63c17263c194860 638 PRINTS PR00097 Anthranilate synthase component II signature 449 463 1.7E-6 T 10-11-2016 A4G23_RS26745 570425dd7e4b1bc8d63c17263c194860 638 SUPERFAMILY SSF52317 445 631 3.48E-22 T 10-11-2016 IPR029062 Class I glutamine amidotransferase-like A4G23_RS26745 570425dd7e4b1bc8d63c17263c194860 638 Gene3D G3DSA:3.60.120.10 104 392 1.8E-59 T 10-11-2016 IPR005801 ADC synthase GO:0009058 A4G23_RS26745 570425dd7e4b1bc8d63c17263c194860 638 Pfam PF00117 Glutamine amidotransferase class-I 451 625 1.5E-20 T 10-11-2016 IPR017926 Glutamine amidotransferase A4G23_RS26745 570425dd7e4b1bc8d63c17263c194860 638 Pfam PF00425 chorismate binding enzyme 124 383 3.5E-46 T 10-11-2016 IPR015890 Chorismate-utilising enzyme, C-terminal A4G23_RS24515 f2141442f447e31242abb8cf8f9dce5a 101 Hamap MF_00434 Putative pterin-4-alpha-carbinolamine dehydratase. 3 95 19.771 T 10-11-2016 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 A4G23_RS24515 f2141442f447e31242abb8cf8f9dce5a 101 Gene3D G3DSA:3.30.1360.20 3 96 4.0E-22 T 10-11-2016 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 A4G23_RS24515 f2141442f447e31242abb8cf8f9dce5a 101 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 5 93 8.5E-23 T 10-11-2016 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 A4G23_RS24515 f2141442f447e31242abb8cf8f9dce5a 101 SUPERFAMILY SSF55248 5 96 1.7E-23 T 10-11-2016 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 A4G23_RS09565 5c2b8d195264cb0f9c92eab28aa6cd7c 65 SUPERFAMILY SSF47598 1 46 2.07E-7 T 10-11-2016 IPR010985 Ribbon-helix-helix GO:0006355 A4G23_RS09565 5c2b8d195264cb0f9c92eab28aa6cd7c 65 Pfam PF03869 Arc-like DNA binding domain 5 45 2.3E-4 T 10-11-2016 IPR005569 Arc-like DNA binding domain GO:0003677 A4G23_RS09565 5c2b8d195264cb0f9c92eab28aa6cd7c 65 Gene3D G3DSA:1.10.1220.10 4 57 6.5E-7 T 10-11-2016 IPR013321 Arc-type ribbon-helix-helix GO:0006355 A4G23_RS04480 af01fbbfb4ad893043cd1ed7393aa621 485 Gene3D G3DSA:3.30.420.40 262 450 3.6E-19 T 10-11-2016 A4G23_RS04480 af01fbbfb4ad893043cd1ed7393aa621 485 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 133 145 - T 10-11-2016 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A4G23_RS04480 af01fbbfb4ad893043cd1ed7393aa621 485 PIRSF PIRSF000538 2 481 9.6E-94 T 10-11-2016 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A4G23_RS04480 af01fbbfb4ad893043cd1ed7393aa621 485 SUPERFAMILY SSF53067 261 471 2.16E-28 T 10-11-2016 A4G23_RS04480 af01fbbfb4ad893043cd1ed7393aa621 485 Gene3D G3DSA:3.30.420.40 2 249 1.2E-63 T 10-11-2016 A4G23_RS04480 af01fbbfb4ad893043cd1ed7393aa621 485 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 249 6.5E-65 T 10-11-2016 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 A4G23_RS04480 af01fbbfb4ad893043cd1ed7393aa621 485 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 263 434 7.7E-15 T 10-11-2016 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 A4G23_RS04480 af01fbbfb4ad893043cd1ed7393aa621 485 SUPERFAMILY SSF53067 4 251 1.12E-63 T 10-11-2016 A4G23_RS04480 af01fbbfb4ad893043cd1ed7393aa621 485 TIGRFAM TIGR01312 XylB: xylulokinase 6 445 3.2E-124 T 10-11-2016 IPR006000 Xylulokinase GO:0004856|GO:0005997 KEGG: 00040+2.7.1.17 A4G23_RS04480 af01fbbfb4ad893043cd1ed7393aa621 485 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 348 368 - T 10-11-2016 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A4G23_RS10990 5a39592cf685ad27b9640d66069dc199 581 Gene3D G3DSA:2.30.38.10 400 472 3.1E-29 T 10-11-2016 A4G23_RS10990 5a39592cf685ad27b9640d66069dc199 581 Gene3D G3DSA:3.40.50.980 229 399 6.2E-37 T 10-11-2016 A4G23_RS10990 5a39592cf685ad27b9640d66069dc199 581 Gene3D G3DSA:3.30.300.30 474 574 2.8E-28 T 10-11-2016 A4G23_RS10990 5a39592cf685ad27b9640d66069dc199 581 SUPERFAMILY SSF56801 43 576 1.15E-132 T 10-11-2016 A4G23_RS10990 5a39592cf685ad27b9640d66069dc199 581 Gene3D G3DSA:3.40.50.980 43 171 3.1E-29 T 10-11-2016 A4G23_RS10990 5a39592cf685ad27b9640d66069dc199 581 Gene3D G3DSA:3.40.50.980 207 228 3.1E-29 T 10-11-2016 A4G23_RS10990 5a39592cf685ad27b9640d66069dc199 581 Pfam PF00501 AMP-binding enzyme 43 479 1.6E-94 T 10-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A4G23_RS10990 5a39592cf685ad27b9640d66069dc199 581 Pfam PF13193 AMP-binding enzyme C-terminal domain 488 565 2.1E-18 T 10-11-2016 IPR025110 AMP-binding enzyme C-terminal domain A4G23_RS10990 5a39592cf685ad27b9640d66069dc199 581 ProSitePatterns PS00455 Putative AMP-binding domain signature. 222 233 - T 10-11-2016 IPR020845 AMP-binding, conserved site A4G23_RS00305 b5ffaa7c9a920b0c859b6c0599340210 85 ProSitePatterns PS00018 EF-hand calcium-binding domain. 14 26 - T 10-11-2016 IPR018247 EF-Hand 1, calcium-binding site A4G23_RS00305 b5ffaa7c9a920b0c859b6c0599340210 85 Gene3D G3DSA:1.10.238.10 3 81 2.9E-13 T 10-11-2016 IPR011992 EF-hand domain pair A4G23_RS00305 b5ffaa7c9a920b0c859b6c0599340210 85 SUPERFAMILY SSF47473 4 80 1.54E-12 T 10-11-2016 IPR011992 EF-hand domain pair A4G23_RS00305 b5ffaa7c9a920b0c859b6c0599340210 85 Pfam PF13499 EF-hand domain pair 4 77 2.0E-9 T 10-11-2016 IPR002048 EF-hand domain GO:0005509 A4G23_RS00305 b5ffaa7c9a920b0c859b6c0599340210 85 SMART SM00054 5 33 0.016 T 10-11-2016 IPR002048 EF-hand domain GO:0005509 A4G23_RS00305 b5ffaa7c9a920b0c859b6c0599340210 85 SMART SM00054 53 81 11.0 T 10-11-2016 IPR002048 EF-hand domain GO:0005509 A4G23_RS08725 88ff0538e06ca7f973a561f7d7e7a06c 972 SUPERFAMILY SSF52540 660 894 3.52E-58 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS08725 88ff0538e06ca7f973a561f7d7e7a06c 972 SMART SM00939 399 619 3.8E-23 T 10-11-2016 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 A4G23_RS08725 88ff0538e06ca7f973a561f7d7e7a06c 972 SMART SM00382 697 877 1.6E-16 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS08725 88ff0538e06ca7f973a561f7d7e7a06c 972 Gene3D G3DSA:3.40.50.300 666 890 8.3E-64 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS08725 88ff0538e06ca7f973a561f7d7e7a06c 972 ProSitePatterns PS00211 ABC transporters family signature. 801 815 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS08725 88ff0538e06ca7f973a561f7d7e7a06c 972 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 77 187 8.2E-17 T 10-11-2016 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 A4G23_RS08725 88ff0538e06ca7f973a561f7d7e7a06c 972 Gene3D G3DSA:2.60.120.260 475 612 7.9E-22 T 10-11-2016 IPR008979 Galactose-binding domain-like A4G23_RS08725 88ff0538e06ca7f973a561f7d7e7a06c 972 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 500 550 7.7E-8 T 10-11-2016 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 A4G23_RS08725 88ff0538e06ca7f973a561f7d7e7a06c 972 SUPERFAMILY SSF53474 40 180 2.8E-48 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS08725 88ff0538e06ca7f973a561f7d7e7a06c 972 SUPERFAMILY SSF53474 303 413 2.8E-48 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS08725 88ff0538e06ca7f973a561f7d7e7a06c 972 Pfam PF00005 ABC transporter 689 829 1.5E-27 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS08725 88ff0538e06ca7f973a561f7d7e7a06c 972 SUPERFAMILY SSF49785 441 619 1.23E-24 T 10-11-2016 IPR008979 Galactose-binding domain-like A4G23_RS08725 88ff0538e06ca7f973a561f7d7e7a06c 972 Gene3D G3DSA:3.40.50.1820 36 184 6.3E-53 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS08725 88ff0538e06ca7f973a561f7d7e7a06c 972 Gene3D G3DSA:3.40.50.1820 300 407 6.3E-53 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS05875 76b8772f949e63e8bb6cf4e27f51c96b 255 SMART SM00382 46 246 2.3E-9 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS05875 76b8772f949e63e8bb6cf4e27f51c96b 255 PIRSF PIRSF039137 17 253 6.7E-107 T 10-11-2016 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 A4G23_RS05875 76b8772f949e63e8bb6cf4e27f51c96b 255 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS05875 76b8772f949e63e8bb6cf4e27f51c96b 255 Gene3D G3DSA:3.40.50.300 18 249 9.1E-61 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05875 76b8772f949e63e8bb6cf4e27f51c96b 255 Pfam PF00005 ABC transporter 37 180 3.9E-29 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS05875 76b8772f949e63e8bb6cf4e27f51c96b 255 SUPERFAMILY SSF52540 20 250 8.63E-60 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS06770 1f3a8aa885b7a59d4dc76d546cf39643 469 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 7 468 1.7E-199 T 10-11-2016 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4G23_RS06770 1f3a8aa885b7a59d4dc76d546cf39643 469 SUPERFAMILY SSF55931 102 468 7.26E-138 T 10-11-2016 A4G23_RS06770 1f3a8aa885b7a59d4dc76d546cf39643 469 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 256 271 - T 10-11-2016 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 A4G23_RS06770 1f3a8aa885b7a59d4dc76d546cf39643 469 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 385 397 - T 10-11-2016 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4G23_RS06770 1f3a8aa885b7a59d4dc76d546cf39643 469 Pfam PF00120 Glutamine synthetase, catalytic domain 102 466 2.9E-138 T 10-11-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4G23_RS06770 1f3a8aa885b7a59d4dc76d546cf39643 469 Gene3D G3DSA:3.10.20.70 5 104 4.0E-33 T 10-11-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4G23_RS06770 1f3a8aa885b7a59d4dc76d546cf39643 469 ProSitePatterns PS00180 Glutamine synthetase signature 1. 49 67 - T 10-11-2016 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 A4G23_RS06770 1f3a8aa885b7a59d4dc76d546cf39643 469 Gene3D G3DSA:3.30.590.10 105 448 5.0E-137 T 10-11-2016 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 A4G23_RS06770 1f3a8aa885b7a59d4dc76d546cf39643 469 SMART SM01230 101 378 3.4E-154 T 10-11-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4G23_RS06770 1f3a8aa885b7a59d4dc76d546cf39643 469 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 94 1.2E-22 T 10-11-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4G23_RS06770 1f3a8aa885b7a59d4dc76d546cf39643 469 SUPERFAMILY SSF54368 5 99 1.18E-28 T 10-11-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4G23_RS09865 a7f6afb92478d8b7b40b19c0625fe540 225 Gene3D G3DSA:3.40.50.2300 2 123 1.1E-40 T 10-11-2016 A4G23_RS09865 a7f6afb92478d8b7b40b19c0625fe540 225 SMART SM00448 3 113 1.4E-44 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS09865 a7f6afb92478d8b7b40b19c0625fe540 225 Pfam PF00072 Response regulator receiver domain 5 114 7.5E-29 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS09865 a7f6afb92478d8b7b40b19c0625fe540 225 Gene3D G3DSA:1.10.10.10 124 222 2.8E-34 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS09865 a7f6afb92478d8b7b40b19c0625fe540 225 SUPERFAMILY SSF52172 4 177 1.99E-43 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS09865 a7f6afb92478d8b7b40b19c0625fe540 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 221 1.8E-25 T 10-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4G23_RS09865 a7f6afb92478d8b7b40b19c0625fe540 225 SMART SM00862 146 222 3.3E-22 T 10-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4G23_RS02675 617118407237bc0d1dbc56ff544743e6 283 Pfam PF13020 Domain of unknown function (DUF3883) 146 216 7.4E-9 T 10-11-2016 IPR024975 Domain of unknown function DUF3883 A4G23_RS19360 35302d9b27459f5de6d5d1d9ed06b0fd 496 SUPERFAMILY SSF56601 147 490 8.2E-76 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS19360 35302d9b27459f5de6d5d1d9ed06b0fd 496 Gene3D G3DSA:3.40.710.10 143 491 4.9E-83 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS19360 35302d9b27459f5de6d5d1d9ed06b0fd 496 Pfam PF00905 Penicillin binding protein transpeptidase domain 161 486 1.9E-55 T 10-11-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A4G23_RS06260 2fda375fd014f596259c216723b24133 476 Pfam PF08245 Mur ligase middle domain 108 297 1.2E-44 T 10-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4G23_RS06260 2fda375fd014f596259c216723b24133 476 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 4 465 32.181 T 10-11-2016 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4G23_RS06260 2fda375fd014f596259c216723b24133 476 Gene3D G3DSA:3.90.190.20 319 466 1.4E-41 T 10-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4G23_RS06260 2fda375fd014f596259c216723b24133 476 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 34 464 1.7E-126 T 10-11-2016 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4G23_RS06260 2fda375fd014f596259c216723b24133 476 SUPERFAMILY SSF63418 3 97 2.62E-22 T 10-11-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 A4G23_RS06260 2fda375fd014f596259c216723b24133 476 Gene3D G3DSA:3.40.1390.10 3 80 1.5E-22 T 10-11-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 A4G23_RS06260 2fda375fd014f596259c216723b24133 476 SUPERFAMILY SSF53623 102 313 9.29E-53 T 10-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4G23_RS06260 2fda375fd014f596259c216723b24133 476 SUPERFAMILY SSF53244 320 464 7.78E-34 T 10-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4G23_RS06260 2fda375fd014f596259c216723b24133 476 Gene3D G3DSA:3.40.1190.10 84 313 5.3E-70 T 10-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4G23_RS06260 2fda375fd014f596259c216723b24133 476 Pfam PF01225 Mur ligase family, catalytic domain 31 94 4.1E-11 T 10-11-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 A4G23_RS06260 2fda375fd014f596259c216723b24133 476 Pfam PF02875 Mur ligase family, glutamate ligase domain 321 405 1.9E-17 T 10-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4G23_RS27180 1f5378af278be51e989320c499ec2253 346 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 250 338 2.1E-30 T 10-11-2016 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A4G23_RS27180 1f5378af278be51e989320c499ec2253 346 SUPERFAMILY SSF53901 13 338 6.4E-60 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS27180 1f5378af278be51e989320c499ec2253 346 Gene3D G3DSA:3.40.47.10 16 170 6.2E-52 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS27180 1f5378af278be51e989320c499ec2253 346 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 14 338 58.152 T 10-11-2016 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A4G23_RS27180 1f5378af278be51e989320c499ec2253 346 Gene3D G3DSA:3.40.47.10 171 339 1.6E-44 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS27180 1f5378af278be51e989320c499ec2253 346 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 17 337 7.1E-92 T 10-11-2016 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A4G23_RS27180 1f5378af278be51e989320c499ec2253 346 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 117 197 2.6E-24 T 10-11-2016 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A4G23_RS11315 6c89f1fc135dba3fc03d714130c263ac 861 Gene3D G3DSA:3.20.20.70 490 826 1.7E-76 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS11315 6c89f1fc135dba3fc03d714130c263ac 861 Gene3D G3DSA:3.20.20.70 28 360 8.0E-65 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS11315 6c89f1fc135dba3fc03d714130c263ac 861 TIGRFAM TIGR03551 F420_cofH: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofH subunit 493 837 1.1E-159 T 10-11-2016 IPR019940 CofH family GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 A4G23_RS11315 6c89f1fc135dba3fc03d714130c263ac 861 SUPERFAMILY SSF102114 29 374 1.44E-36 T 10-11-2016 A4G23_RS11315 6c89f1fc135dba3fc03d714130c263ac 861 Hamap MF_01611 FO synthase subunit 1 [cofG]. 68 399 49.493 T 10-11-2016 IPR019939 CofG family GO:0009108|GO:0016765|GO:0051539 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 A4G23_RS11315 6c89f1fc135dba3fc03d714130c263ac 861 TIGRFAM TIGR03550 F420_cofG: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofG subunit 69 397 1.4E-140 T 10-11-2016 IPR019939 CofG family GO:0009108|GO:0016765|GO:0051539 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 A4G23_RS11315 6c89f1fc135dba3fc03d714130c263ac 861 SMART SM00729 531 756 0.012 T 10-11-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 A4G23_RS11315 6c89f1fc135dba3fc03d714130c263ac 861 SMART SM00729 72 309 4.1E-9 T 10-11-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 A4G23_RS11315 6c89f1fc135dba3fc03d714130c263ac 861 SUPERFAMILY SSF102114 490 801 4.84E-50 T 10-11-2016 A4G23_RS11315 6c89f1fc135dba3fc03d714130c263ac 861 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 527 835 4.3E-108 T 10-11-2016 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 A4G23_RS11315 6c89f1fc135dba3fc03d714130c263ac 861 Pfam PF04055 Radical SAM superfamily 77 258 4.8E-13 T 10-11-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 A4G23_RS11315 6c89f1fc135dba3fc03d714130c263ac 861 Pfam PF04055 Radical SAM superfamily 535 695 7.7E-15 T 10-11-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 A4G23_RS11315 6c89f1fc135dba3fc03d714130c263ac 861 Hamap MF_01612 FO synthase subunit 2 [cofH]. 479 838 48.245 T 10-11-2016 IPR019940 CofH family GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 A4G23_RS06280 bdfb7c531426b55f407aff50be0a1b43 308 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 15 303 7.3E-90 T 10-11-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A4G23_RS06280 bdfb7c531426b55f407aff50be0a1b43 308 PIRSF PIRSF004486 1 305 3.3E-93 T 10-11-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A4G23_RS06280 bdfb7c531426b55f407aff50be0a1b43 308 SUPERFAMILY SSF53335 209 304 7.21E-38 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS06280 bdfb7c531426b55f407aff50be0a1b43 308 SUPERFAMILY SSF53335 2 107 7.21E-38 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS06280 bdfb7c531426b55f407aff50be0a1b43 308 Gene3D G3DSA:1.10.150.170 107 211 2.8E-35 T 10-11-2016 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A4G23_RS06280 bdfb7c531426b55f407aff50be0a1b43 308 SUPERFAMILY SSF81799 108 209 1.26E-32 T 10-11-2016 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A4G23_RS06280 bdfb7c531426b55f407aff50be0a1b43 308 Gene3D G3DSA:3.40.50.150 1 104 1.9E-47 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS06280 bdfb7c531426b55f407aff50be0a1b43 308 Gene3D G3DSA:3.40.50.150 212 306 1.9E-47 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS06280 bdfb7c531426b55f407aff50be0a1b43 308 Pfam PF01795 MraW methylase family 1 303 3.7E-107 T 10-11-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A4G23_RS06280 bdfb7c531426b55f407aff50be0a1b43 308 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 1 304 34.741 T 10-11-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A4G23_RS22380 a081f6c6e67c1fbd02c87bd3152ad655 323 Gene3D G3DSA:3.40.50.300 10 238 2.0E-69 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS22380 a081f6c6e67c1fbd02c87bd3152ad655 323 SUPERFAMILY SSF52540 13 238 1.74E-64 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS22380 a081f6c6e67c1fbd02c87bd3152ad655 323 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS22380 a081f6c6e67c1fbd02c87bd3152ad655 323 SMART SM00382 43 221 3.3E-15 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS22380 a081f6c6e67c1fbd02c87bd3152ad655 323 Pfam PF00005 ABC transporter 35 174 9.8E-28 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS02260 f29e09034acb9bc3d987afd5cd2aa1df 496 ProSitePatterns PS00455 Putative AMP-binding domain signature. 150 161 - T 10-11-2016 IPR020845 AMP-binding, conserved site A4G23_RS02260 f29e09034acb9bc3d987afd5cd2aa1df 496 Gene3D G3DSA:3.30.300.30 401 493 2.4E-19 T 10-11-2016 A4G23_RS02260 f29e09034acb9bc3d987afd5cd2aa1df 496 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 33 430 1.5E-101 T 10-11-2016 IPR010071 Amino acid adenylation domain A4G23_RS02260 f29e09034acb9bc3d987afd5cd2aa1df 496 SUPERFAMILY SSF56801 5 493 1.14E-112 T 10-11-2016 A4G23_RS02260 f29e09034acb9bc3d987afd5cd2aa1df 496 Gene3D G3DSA:3.40.50.980 160 309 1.2E-36 T 10-11-2016 A4G23_RS02260 f29e09034acb9bc3d987afd5cd2aa1df 496 Pfam PF00501 AMP-binding enzyme 16 407 1.2E-76 T 10-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A4G23_RS02260 f29e09034acb9bc3d987afd5cd2aa1df 496 Gene3D G3DSA:2.30.38.10 321 399 5.3E-16 T 10-11-2016 A4G23_RS02260 f29e09034acb9bc3d987afd5cd2aa1df 496 Gene3D G3DSA:3.40.50.980 5 159 1.3E-32 T 10-11-2016 A4G23_RS00585 f82f2bdeaa06e3cff396529cf6c36910 371 Pfam PF01636 Phosphotransferase enzyme family 87 299 9.2E-15 T 10-11-2016 IPR002575 Aminoglycoside phosphotransferase A4G23_RS00585 f82f2bdeaa06e3cff396529cf6c36910 371 SUPERFAMILY SSF56112 82 308 1.66E-25 T 10-11-2016 IPR011009 Protein kinase-like domain A4G23_RS00585 f82f2bdeaa06e3cff396529cf6c36910 371 Gene3D G3DSA:3.90.1200.10 149 302 1.1E-11 T 10-11-2016 A4G23_RS02310 519d1b915a6312642ce9d3f2e5e59a1f 88 Pfam PF00550 Phosphopantetheine attachment site 14 82 2.3E-9 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS02310 519d1b915a6312642ce9d3f2e5e59a1f 88 Gene3D G3DSA:1.10.1200.10 10 84 1.2E-17 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS02310 519d1b915a6312642ce9d3f2e5e59a1f 88 SUPERFAMILY SSF47336 9 85 6.28E-15 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS02170 1affb97e35a1e743bbac839a147d79f7 429 Gene3D G3DSA:3.40.190.10 337 366 2.3E-20 T 10-11-2016 A4G23_RS02170 1affb97e35a1e743bbac839a147d79f7 429 Gene3D G3DSA:3.40.190.10 11 150 2.3E-20 T 10-11-2016 A4G23_RS02170 1affb97e35a1e743bbac839a147d79f7 429 SUPERFAMILY SSF53850 26 429 1.25E-67 T 10-11-2016 A4G23_RS02170 1affb97e35a1e743bbac839a147d79f7 429 Pfam PF01547 Bacterial extracellular solute-binding protein 56 343 9.9E-33 T 10-11-2016 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 A4G23_RS02170 1affb97e35a1e743bbac839a147d79f7 429 Gene3D G3DSA:3.40.190.10 156 336 1.9E-31 T 10-11-2016 A4G23_RS04570 f5642aded1575037bc343dbe9a674510 438 PIRSF PIRSF016719 49 438 7.5E-149 T 10-11-2016 IPR008302 Uncharacterised conserved protein UCP016719 A4G23_RS04570 f5642aded1575037bc343dbe9a674510 438 Pfam PF07075 Protein of unknown function (DUF1343) 79 437 6.4E-130 T 10-11-2016 IPR008302 Uncharacterised conserved protein UCP016719 A4G23_RS00500 ba7efe2408a4001c88b66c919d1aa4cf 78 Pfam PF05120 Gas vesicle protein G 7 73 3.2E-27 T 10-11-2016 IPR007804 Gas vesicle protein GvpG A4G23_RS24095 7ea386f0c9dd7ce3d9e060e4b76f02f4 620 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 67 602 4.4E-116 T 10-11-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A4G23_RS24095 7ea386f0c9dd7ce3d9e060e4b76f02f4 620 SUPERFAMILY SSF56235 59 612 1.66E-153 T 10-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal A4G23_RS24095 7ea386f0c9dd7ce3d9e060e4b76f02f4 620 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 162 180 6.5E-69 T 10-11-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A4G23_RS24095 7ea386f0c9dd7ce3d9e060e4b76f02f4 620 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 319 338 6.5E-69 T 10-11-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A4G23_RS24095 7ea386f0c9dd7ce3d9e060e4b76f02f4 620 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 515 532 6.5E-69 T 10-11-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A4G23_RS24095 7ea386f0c9dd7ce3d9e060e4b76f02f4 620 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 454 472 6.5E-69 T 10-11-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A4G23_RS24095 7ea386f0c9dd7ce3d9e060e4b76f02f4 620 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 430 448 6.5E-69 T 10-11-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A4G23_RS24095 7ea386f0c9dd7ce3d9e060e4b76f02f4 620 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 289 305 6.5E-69 T 10-11-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A4G23_RS24095 7ea386f0c9dd7ce3d9e060e4b76f02f4 620 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 180 199 6.5E-69 T 10-11-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A4G23_RS24095 7ea386f0c9dd7ce3d9e060e4b76f02f4 620 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 88 113 6.5E-69 T 10-11-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A4G23_RS24095 7ea386f0c9dd7ce3d9e060e4b76f02f4 620 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 490 505 6.5E-69 T 10-11-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A4G23_RS24095 7ea386f0c9dd7ce3d9e060e4b76f02f4 620 Pfam PF01019 Gamma-glutamyltranspeptidase 81 608 1.0E-151 T 10-11-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A4G23_RS25625 153dae0de3492c829ed48f051ba64c76 989 Pfam PF00041 Fibronectin type III domain 255 328 2.6E-6 T 10-11-2016 IPR003961 Fibronectin type III GO:0005515 A4G23_RS25625 153dae0de3492c829ed48f051ba64c76 989 SUPERFAMILY SSF51445 709 900 2.71E-70 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS25625 153dae0de3492c829ed48f051ba64c76 989 SUPERFAMILY SSF51445 336 635 2.71E-70 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS25625 153dae0de3492c829ed48f051ba64c76 989 SMART SM00060 252 328 7.8E-9 T 10-11-2016 IPR003961 Fibronectin type III GO:0005515 A4G23_RS25625 153dae0de3492c829ed48f051ba64c76 989 Gene3D G3DSA:2.60.40.1180 934 973 1.7E-4 T 10-11-2016 IPR013780 Glycosyl hydrolase, all-beta A4G23_RS25625 153dae0de3492c829ed48f051ba64c76 989 Pfam PF00128 Alpha amylase, catalytic domain 398 683 1.3E-28 T 10-11-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A4G23_RS25625 153dae0de3492c829ed48f051ba64c76 989 Gene3D G3DSA:2.60.40.10 250 339 1.8E-17 T 10-11-2016 IPR013783 Immunoglobulin-like fold A4G23_RS25625 153dae0de3492c829ed48f051ba64c76 989 SMART SM00642 363 891 1.0E-34 T 10-11-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A4G23_RS25625 153dae0de3492c829ed48f051ba64c76 989 Pfam PF03423 Carbohydrate binding domain (family 25) 44 138 2.7E-33 T 10-11-2016 IPR005085 Carbohydrate binding module family 25 GO:2001070 A4G23_RS25625 153dae0de3492c829ed48f051ba64c76 989 Pfam PF03423 Carbohydrate binding domain (family 25) 143 247 1.8E-46 T 10-11-2016 IPR005085 Carbohydrate binding module family 25 GO:2001070 A4G23_RS25625 153dae0de3492c829ed48f051ba64c76 989 SMART SM01066 42 122 2.7E-23 T 10-11-2016 IPR005085 Carbohydrate binding module family 25 GO:2001070 A4G23_RS25625 153dae0de3492c829ed48f051ba64c76 989 SMART SM01066 145 225 2.1E-30 T 10-11-2016 IPR005085 Carbohydrate binding module family 25 GO:2001070 A4G23_RS25625 153dae0de3492c829ed48f051ba64c76 989 Gene3D G3DSA:3.20.20.80 728 846 7.2E-93 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS25625 153dae0de3492c829ed48f051ba64c76 989 Gene3D G3DSA:3.20.20.80 546 669 7.2E-93 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS25625 153dae0de3492c829ed48f051ba64c76 989 Gene3D G3DSA:3.20.20.80 396 484 7.2E-93 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS25625 153dae0de3492c829ed48f051ba64c76 989 Gene3D G3DSA:3.20.20.80 353 364 7.2E-93 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS25625 153dae0de3492c829ed48f051ba64c76 989 Gene3D G3DSA:3.20.20.80 879 910 7.2E-93 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS25625 153dae0de3492c829ed48f051ba64c76 989 SUPERFAMILY SSF49265 249 351 4.87E-15 T 10-11-2016 IPR003961 Fibronectin type III GO:0005515 A4G23_RS03650 418f64adba290a8aeefb43079664d98a 204 SUPERFAMILY SSF55174 6 204 1.7E-55 T 10-11-2016 A4G23_RS03650 418f64adba290a8aeefb43079664d98a 204 ProSitePatterns PS00632 Ribosomal protein S4 signature. 90 114 - T 10-11-2016 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS03650 418f64adba290a8aeefb43079664d98a 204 Gene3D G3DSA:3.10.290.10 98 188 9.6E-25 T 10-11-2016 IPR002942 RNA-binding S4 domain GO:0003723 A4G23_RS03650 418f64adba290a8aeefb43079664d98a 204 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 6 204 2.5E-61 T 10-11-2016 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 A4G23_RS03650 418f64adba290a8aeefb43079664d98a 204 SMART SM00363 92 152 5.9E-15 T 10-11-2016 IPR002942 RNA-binding S4 domain GO:0003723 A4G23_RS03650 418f64adba290a8aeefb43079664d98a 204 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 6 91 1.2E-17 T 10-11-2016 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 A4G23_RS03650 418f64adba290a8aeefb43079664d98a 204 Gene3D G3DSA:1.10.1050.10 5 97 4.2E-27 T 10-11-2016 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 A4G23_RS03650 418f64adba290a8aeefb43079664d98a 204 SMART SM01390 3 91 1.2E-31 T 10-11-2016 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 A4G23_RS03650 418f64adba290a8aeefb43079664d98a 204 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 204 29.269 T 10-11-2016 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 A4G23_RS03650 418f64adba290a8aeefb43079664d98a 204 Pfam PF01479 S4 domain 92 139 1.0E-17 T 10-11-2016 IPR002942 RNA-binding S4 domain GO:0003723 A4G23_RS12115 6cc48d96d5d63ef32a82975ab1154cda 332 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 92 1.2E-5 T 10-11-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A4G23_RS12115 6cc48d96d5d63ef32a82975ab1154cda 332 SUPERFAMILY SSF51735 116 256 5.92E-29 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS12115 6cc48d96d5d63ef32a82975ab1154cda 332 SMART SM00829 10 330 3.1E-11 T 10-11-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A4G23_RS12115 6cc48d96d5d63ef32a82975ab1154cda 332 SUPERFAMILY SSF50129 302 330 3.62E-28 T 10-11-2016 IPR011032 GroES-like A4G23_RS12115 6cc48d96d5d63ef32a82975ab1154cda 332 SUPERFAMILY SSF50129 1 121 3.62E-28 T 10-11-2016 IPR011032 GroES-like A4G23_RS12115 6cc48d96d5d63ef32a82975ab1154cda 332 Gene3D G3DSA:3.90.180.10 1 149 1.0E-28 T 10-11-2016 IPR011032 GroES-like A4G23_RS12115 6cc48d96d5d63ef32a82975ab1154cda 332 Gene3D G3DSA:3.40.50.720 150 248 1.1E-18 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS12115 6cc48d96d5d63ef32a82975ab1154cda 332 Pfam PF13602 Zinc-binding dehydrogenase 188 330 1.9E-17 T 10-11-2016 A4G23_RS12365 456a7a12f42c696c9059f01dff4a8495 270 Gene3D G3DSA:3.40.50.300 14 241 3.2E-71 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS12365 456a7a12f42c696c9059f01dff4a8495 270 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS12365 456a7a12f42c696c9059f01dff4a8495 270 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 28 253 9.7E-95 T 10-11-2016 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 A4G23_RS12365 456a7a12f42c696c9059f01dff4a8495 270 SUPERFAMILY SSF52540 17 241 5.44E-61 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS12365 456a7a12f42c696c9059f01dff4a8495 270 SMART SM00382 45 228 3.0E-10 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS12365 456a7a12f42c696c9059f01dff4a8495 270 Pfam PF00005 ABC transporter 36 179 3.9E-26 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS19005 38f8ce1504e34ba626f8daa4a1715511 261 SUPERFAMILY SSF46785 23 94 1.36E-18 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS19005 38f8ce1504e34ba626f8daa4a1715511 261 Gene3D G3DSA:3.40.1410.10 88 257 4.0E-57 T 10-11-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain A4G23_RS19005 38f8ce1504e34ba626f8daa4a1715511 261 Gene3D G3DSA:1.10.10.10 24 87 5.5E-22 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS19005 38f8ce1504e34ba626f8daa4a1715511 261 Pfam PF07702 UTRA domain 110 250 6.7E-43 T 10-11-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A4G23_RS19005 38f8ce1504e34ba626f8daa4a1715511 261 Pfam PF00392 Bacterial regulatory proteins, gntR family 41 90 9.6E-17 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS19005 38f8ce1504e34ba626f8daa4a1715511 261 SMART SM00866 110 250 2.5E-44 T 10-11-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A4G23_RS19005 38f8ce1504e34ba626f8daa4a1715511 261 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 64 80 2.7E-8 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS19005 38f8ce1504e34ba626f8daa4a1715511 261 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 64 2.7E-8 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS19005 38f8ce1504e34ba626f8daa4a1715511 261 SUPERFAMILY SSF64288 78 257 6.6E-56 T 10-11-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain A4G23_RS19005 38f8ce1504e34ba626f8daa4a1715511 261 SMART SM00345 33 90 3.2E-15 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS07785 c695b68b72ba955c9585c76f924fe06a 903 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 538 891 1.4E-84 T 10-11-2016 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 A4G23_RS07785 c695b68b72ba955c9585c76f924fe06a 903 Gene3D G3DSA:1.10.189.10 345 403 2.9E-24 T 10-11-2016 A4G23_RS07785 c695b68b72ba955c9585c76f924fe06a 903 Gene3D G3DSA:3.30.1490.20 203 246 9.7E-58 T 10-11-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A4G23_RS07785 c695b68b72ba955c9585c76f924fe06a 903 Gene3D G3DSA:3.30.1490.20 8 114 9.7E-58 T 10-11-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A4G23_RS07785 c695b68b72ba955c9585c76f924fe06a 903 SUPERFAMILY SSF52009 393 514 1.03E-33 T 10-11-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A4G23_RS07785 c695b68b72ba955c9585c76f924fe06a 903 Gene3D G3DSA:1.20.80.30 115 201 1.8E-35 T 10-11-2016 A4G23_RS07785 c695b68b72ba955c9585c76f924fe06a 903 SUPERFAMILY SSF56059 7 380 1.18E-132 T 10-11-2016 A4G23_RS07785 c695b68b72ba955c9585c76f924fe06a 903 Pfam PF00391 PEP-utilising enzyme, mobile domain 423 505 3.0E-25 T 10-11-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A4G23_RS07785 c695b68b72ba955c9585c76f924fe06a 903 Gene3D G3DSA:3.50.30.10 404 508 9.2E-38 T 10-11-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A4G23_RS07785 c695b68b72ba955c9585c76f924fe06a 903 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 298 355 5.0E-9 T 10-11-2016 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 A4G23_RS07785 c695b68b72ba955c9585c76f924fe06a 903 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 22 290 1.4E-42 T 10-11-2016 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 A4G23_RS07785 c695b68b72ba955c9585c76f924fe06a 903 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 451 462 - T 10-11-2016 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 A4G23_RS07785 c695b68b72ba955c9585c76f924fe06a 903 Gene3D G3DSA:3.20.20.60 552 895 4.0E-127 T 10-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A4G23_RS07785 c695b68b72ba955c9585c76f924fe06a 903 Gene3D G3DSA:3.30.470.20 247 344 7.1E-33 T 10-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 A4G23_RS07785 c695b68b72ba955c9585c76f924fe06a 903 SUPERFAMILY SSF51621 541 893 4.71E-114 T 10-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A4G23_RS07785 c695b68b72ba955c9585c76f924fe06a 903 PIRSF PIRSF000853 6 903 0.0 T 10-11-2016 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A4G23_RS07785 c695b68b72ba955c9585c76f924fe06a 903 TIGRFAM TIGR01828 pyru_phos_dikin: pyruvate, phosphate dikinase 7 894 0.0 T 10-11-2016 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A4G23_RS11965 baa05ace278c12c83c51cb36117ace9d 332 SUPERFAMILY SSF51430 1 321 1.44E-96 T 10-11-2016 IPR023210 NADP-dependent oxidoreductase domain A4G23_RS11965 baa05ace278c12c83c51cb36117ace9d 332 Gene3D G3DSA:3.20.20.100 1 320 1.2E-98 T 10-11-2016 IPR023210 NADP-dependent oxidoreductase domain A4G23_RS11965 baa05ace278c12c83c51cb36117ace9d 332 Pfam PF00248 Aldo/keto reductase family 15 319 1.3E-71 T 10-11-2016 IPR023210 NADP-dependent oxidoreductase domain A4G23_RS26945 4d2dc09e2c34b46d5814f5199692cb74 393 Gene3D G3DSA:1.10.630.10 12 392 1.6E-107 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS26945 4d2dc09e2c34b46d5814f5199692cb74 393 SUPERFAMILY SSF48264 19 392 3.8E-84 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS26945 4d2dc09e2c34b46d5814f5199692cb74 393 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 334 343 - T 10-11-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A4G23_RS26945 4d2dc09e2c34b46d5814f5199692cb74 393 Pfam PF00067 Cytochrome P450 265 362 1.7E-17 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS26945 4d2dc09e2c34b46d5814f5199692cb74 393 PRINTS PR00359 B-class P450 signature 264 275 2.9E-51 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS26945 4d2dc09e2c34b46d5814f5199692cb74 393 PRINTS PR00359 B-class P450 signature 341 352 2.9E-51 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS26945 4d2dc09e2c34b46d5814f5199692cb74 393 PRINTS PR00359 B-class P450 signature 84 95 2.9E-51 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS26945 4d2dc09e2c34b46d5814f5199692cb74 393 PRINTS PR00359 B-class P450 signature 332 341 2.9E-51 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS26945 4d2dc09e2c34b46d5814f5199692cb74 393 PRINTS PR00359 B-class P450 signature 148 163 2.9E-51 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS26945 4d2dc09e2c34b46d5814f5199692cb74 393 PRINTS PR00359 B-class P450 signature 185 207 2.9E-51 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS26945 4d2dc09e2c34b46d5814f5199692cb74 393 PRINTS PR00359 B-class P450 signature 283 310 2.9E-51 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS26945 4d2dc09e2c34b46d5814f5199692cb74 393 PRINTS PR00359 B-class P450 signature 131 147 2.9E-51 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS26945 4d2dc09e2c34b46d5814f5199692cb74 393 PRINTS PR00359 B-class P450 signature 311 326 2.9E-51 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS10420 ac4ade2bd0161094f43e355c75b00c3a 320 Gene3D G3DSA:3.90.550.10 2 120 1.2E-26 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS10420 ac4ade2bd0161094f43e355c75b00c3a 320 SUPERFAMILY SSF53448 2 219 9.38E-39 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS10420 ac4ade2bd0161094f43e355c75b00c3a 320 Pfam PF00535 Glycosyl transferase family 2 4 166 1.3E-33 T 10-11-2016 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A4G23_RS07550 87fcd330bfe84bfad1f70f16e6c5610d 145 Pfam PF12802 MarR family 36 92 9.9E-15 T 10-11-2016 A4G23_RS07550 87fcd330bfe84bfad1f70f16e6c5610d 145 SUPERFAMILY SSF46785 8 139 1.67E-27 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS07550 87fcd330bfe84bfad1f70f16e6c5610d 145 Gene3D G3DSA:1.10.10.10 4 139 2.4E-31 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS07550 87fcd330bfe84bfad1f70f16e6c5610d 145 SMART SM00347 30 128 4.5E-17 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS07550 87fcd330bfe84bfad1f70f16e6c5610d 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 1.2E-9 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS07550 87fcd330bfe84bfad1f70f16e6c5610d 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 118 138 1.2E-9 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS07550 87fcd330bfe84bfad1f70f16e6c5610d 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 1.2E-9 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS07550 87fcd330bfe84bfad1f70f16e6c5610d 145 ProSitePatterns PS01117 MarR-type HTH domain signature. 68 102 - T 10-11-2016 IPR023187 Transcriptional regulator MarR-type, conserved site A4G23_RS11155 8a1892833d2a08a47820acd1b69be147 269 Gene3D G3DSA:3.60.130.10 9 268 7.7E-55 T 10-11-2016 A4G23_RS11155 8a1892833d2a08a47820acd1b69be147 269 SUPERFAMILY SSF51197 14 268 1.65E-55 T 10-11-2016 A4G23_RS11155 8a1892833d2a08a47820acd1b69be147 269 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 16 266 2.3E-46 T 10-11-2016 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 A4G23_RS20175 5ba0c8a020cba33c63ee27c4ba997c61 249 Pfam PF00699 Urease beta subunit 123 202 4.2E-28 T 10-11-2016 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4G23_RS20175 5ba0c8a020cba33c63ee27c4ba997c61 249 PIRSF PIRSF001225 1 225 2.9E-81 T 10-11-2016 IPR008223 Urease, gamma-beta subunit GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4G23_RS20175 5ba0c8a020cba33c63ee27c4ba997c61 249 TIGRFAM TIGR00193 urease_gam: urease, gamma subunit 2 99 4.7E-31 T 10-11-2016 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4G23_RS20175 5ba0c8a020cba33c63ee27c4ba997c61 249 Gene3D G3DSA:3.30.280.10 2 99 9.2E-36 T 10-11-2016 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4G23_RS20175 5ba0c8a020cba33c63ee27c4ba997c61 249 SUPERFAMILY SSF54111 2 100 1.03E-31 T 10-11-2016 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4G23_RS20175 5ba0c8a020cba33c63ee27c4ba997c61 249 Pfam PF00547 Urease, gamma subunit 2 99 6.7E-35 T 10-11-2016 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4G23_RS20175 5ba0c8a020cba33c63ee27c4ba997c61 249 ProDom PD002319 SUBUNIT GAMMA HYDROLASE UREASE UREA AMIDOHYDROLASE UREASE ALPHA GAMMA/BETA METAL-BINDING 31 99 2.0E-27 T 10-11-2016 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4G23_RS20175 5ba0c8a020cba33c63ee27c4ba997c61 249 SUPERFAMILY SSF51278 112 225 1.57E-35 T 10-11-2016 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4G23_RS20175 5ba0c8a020cba33c63ee27c4ba997c61 249 Gene3D G3DSA:2.10.150.10 123 225 8.5E-36 T 10-11-2016 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4G23_RS16180 16cbee2720c9e154bd96b40fe79289a8 371 Pfam PF13796 Putative sensor 7 123 8.0E-28 T 10-11-2016 IPR025828 Putative sensor domain A4G23_RS16180 16cbee2720c9e154bd96b40fe79289a8 371 SUPERFAMILY SSF55874 274 360 1.57E-13 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS16180 16cbee2720c9e154bd96b40fe79289a8 371 Pfam PF07730 Histidine kinase 175 240 6.4E-13 T 10-11-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4G23_RS16180 16cbee2720c9e154bd96b40fe79289a8 371 Gene3D G3DSA:3.30.565.10 273 362 5.1E-5 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS21885 78f0f7380985f38a0c709b01fb39b04f 572 Gene3D G3DSA:3.30.565.10 304 416 2.0E-14 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS21885 78f0f7380985f38a0c709b01fb39b04f 572 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 305 411 2.5E-10 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS21885 78f0f7380985f38a0c709b01fb39b04f 572 SMART SM00387 302 413 8.9E-10 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS21885 78f0f7380985f38a0c709b01fb39b04f 572 SUPERFAMILY SSF55874 296 412 5.34E-15 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS07195 8a294eacaf367e99859d16c04268335a 659 SMART SM00382 28 219 2.6E-12 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS07195 8a294eacaf367e99859d16c04268335a 659 SMART SM00382 438 618 5.5E-13 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS07195 8a294eacaf367e99859d16c04268335a 659 SUPERFAMILY SSF52540 414 630 3.46E-51 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS07195 8a294eacaf367e99859d16c04268335a 659 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS07195 8a294eacaf367e99859d16c04268335a 659 Gene3D G3DSA:3.40.50.300 2 230 4.3E-60 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS07195 8a294eacaf367e99859d16c04268335a 659 Pfam PF00005 ABC transporter 429 570 1.2E-22 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS07195 8a294eacaf367e99859d16c04268335a 659 Pfam PF00005 ABC transporter 19 170 8.9E-25 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS07195 8a294eacaf367e99859d16c04268335a 659 Gene3D G3DSA:3.40.50.300 415 630 1.3E-52 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS07195 8a294eacaf367e99859d16c04268335a 659 SUPERFAMILY SSF52540 1 233 3.3E-56 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS13290 ec24bee068b45a669f943ba1cba9804b 246 PIRSF PIRSF037834 1 246 9.8E-89 T 10-11-2016 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 A4G23_RS13290 ec24bee068b45a669f943ba1cba9804b 246 Pfam PF05138 Phenylacetic acid catabolic protein 4 246 2.1E-72 T 10-11-2016 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 A4G23_RS13290 ec24bee068b45a669f943ba1cba9804b 246 TIGRFAM TIGR02158 PA_CoA_Oxy3: phenylacetate-CoA oxygenase, PaaI subunit 12 246 2.3E-73 T 10-11-2016 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 A4G23_RS13290 ec24bee068b45a669f943ba1cba9804b 246 SUPERFAMILY SSF47240 5 240 6.89E-63 T 10-11-2016 IPR009078 Ferritin-like superfamily A4G23_RS13290 ec24bee068b45a669f943ba1cba9804b 246 Gene3D G3DSA:1.20.1260.10 3 246 1.2E-79 T 10-11-2016 IPR012347 Ferritin-related A4G23_RS04345 ab0cce6d4ccd382cd889ebb13cfbc148 223 Pfam PF00072 Response regulator receiver domain 5 119 1.3E-28 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS04345 ab0cce6d4ccd382cd889ebb13cfbc148 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 3.7E-15 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS04345 ab0cce6d4ccd382cd889ebb13cfbc148 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 3.7E-15 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS04345 ab0cce6d4ccd382cd889ebb13cfbc148 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 3.7E-15 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS04345 ab0cce6d4ccd382cd889ebb13cfbc148 223 Pfam PF00196 Bacterial regulatory proteins, luxR family 157 212 2.6E-21 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS04345 ab0cce6d4ccd382cd889ebb13cfbc148 223 SMART SM00448 3 118 7.7E-37 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS04345 ab0cce6d4ccd382cd889ebb13cfbc148 223 Gene3D G3DSA:3.40.50.2300 3 125 1.5E-39 T 10-11-2016 A4G23_RS04345 ab0cce6d4ccd382cd889ebb13cfbc148 223 Gene3D G3DSA:1.10.10.10 126 220 2.5E-35 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS04345 ab0cce6d4ccd382cd889ebb13cfbc148 223 SUPERFAMILY SSF52172 3 137 1.2E-35 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS04345 ab0cce6d4ccd382cd889ebb13cfbc148 223 SMART SM00421 155 212 8.4E-29 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS04345 ab0cce6d4ccd382cd889ebb13cfbc148 223 ProSitePatterns PS00622 LuxR-type HTH domain signature. 172 199 - T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS04345 ab0cce6d4ccd382cd889ebb13cfbc148 223 SUPERFAMILY SSF46894 146 218 1.05E-23 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS22695 00665f85b85ab0e95b4a1c2a0d50f295 854 Pfam PF16542 PNKP adenylyltransferase domain, ligase domain 471 791 6.5E-143 T 10-11-2016 IPR032380 Polynucleotide kinase-phosphatase, ligase domain A4G23_RS22695 00665f85b85ab0e95b4a1c2a0d50f295 854 Gene3D G3DSA:3.40.50.300 25 152 6.4E-27 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS22695 00665f85b85ab0e95b4a1c2a0d50f295 854 SUPERFAMILY SSF56091 679 766 3.96E-12 T 10-11-2016 A4G23_RS22695 00665f85b85ab0e95b4a1c2a0d50f295 854 SUPERFAMILY SSF56091 469 610 3.96E-12 T 10-11-2016 A4G23_RS22695 00665f85b85ab0e95b4a1c2a0d50f295 854 Gene3D G3DSA:3.60.21.10 192 428 3.6E-53 T 10-11-2016 IPR029052 Metallo-dependent phosphatase-like A4G23_RS22695 00665f85b85ab0e95b4a1c2a0d50f295 854 TIGRFAM TIGR04075 bacter_Pnkp: polynucleotide kinase-phosphatase 18 854 0.0 T 10-11-2016 IPR024028 Polynucleotide kinase-phosphatase, bacterial A4G23_RS22695 00665f85b85ab0e95b4a1c2a0d50f295 854 SUPERFAMILY SSF52540 25 151 1.15E-16 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS22695 00665f85b85ab0e95b4a1c2a0d50f295 854 Pfam PF00149 Calcineurin-like phosphoesterase 197 388 7.3E-13 T 10-11-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 A4G23_RS22695 00665f85b85ab0e95b4a1c2a0d50f295 854 Pfam PF13671 AAA domain 25 153 3.6E-25 T 10-11-2016 A4G23_RS22695 00665f85b85ab0e95b4a1c2a0d50f295 854 SUPERFAMILY SSF56300 132 406 5.43E-46 T 10-11-2016 IPR029052 Metallo-dependent phosphatase-like A4G23_RS22695 00665f85b85ab0e95b4a1c2a0d50f295 854 Pfam PF16536 PNKP adenylyltransferase domain, C-terminal region 795 854 6.9E-32 T 10-11-2016 IPR032390 Polynucleotide kinase-phosphatase, C-terminal A4G23_RS05725 07b63334deb5b60ea0d3445ffd938a32 430 Pfam PF07690 Major Facilitator Superfamily 271 416 1.5E-8 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS05725 07b63334deb5b60ea0d3445ffd938a32 430 ProSitePatterns PS00217 Sugar transport proteins signature 2. 115 140 - T 10-11-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A4G23_RS05725 07b63334deb5b60ea0d3445ffd938a32 430 Gene3D G3DSA:1.20.1250.20 12 210 5.2E-21 T 10-11-2016 A4G23_RS05725 07b63334deb5b60ea0d3445ffd938a32 430 Gene3D G3DSA:1.20.1250.20 228 414 2.2E-19 T 10-11-2016 A4G23_RS05725 07b63334deb5b60ea0d3445ffd938a32 430 SUPERFAMILY SSF103473 2 414 2.22E-58 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS05725 07b63334deb5b60ea0d3445ffd938a32 430 Pfam PF00083 Sugar (and other) transporter 8 206 7.3E-21 T 10-11-2016 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 A4G23_RS09695 9be20e6fa6a3ceebd51d4ca3d7f1d163 321 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 7.8E-21 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS09695 9be20e6fa6a3ceebd51d4ca3d7f1d163 321 Gene3D G3DSA:3.40.190.10 133 179 1.5E-8 T 10-11-2016 A4G23_RS09695 9be20e6fa6a3ceebd51d4ca3d7f1d163 321 Gene3D G3DSA:3.40.190.10 180 222 2.7E-5 T 10-11-2016 A4G23_RS09695 9be20e6fa6a3ceebd51d4ca3d7f1d163 321 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 6.2E-10 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS09695 9be20e6fa6a3ceebd51d4ca3d7f1d163 321 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 6.2E-10 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS09695 9be20e6fa6a3ceebd51d4ca3d7f1d163 321 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 6.2E-10 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS09695 9be20e6fa6a3ceebd51d4ca3d7f1d163 321 SUPERFAMILY SSF53850 108 299 2.35E-11 T 10-11-2016 A4G23_RS09695 9be20e6fa6a3ceebd51d4ca3d7f1d163 321 Pfam PF03466 LysR substrate binding domain 109 293 6.9E-9 T 10-11-2016 IPR005119 LysR, substrate-binding A4G23_RS09695 9be20e6fa6a3ceebd51d4ca3d7f1d163 321 SUPERFAMILY SSF46785 4 85 6.9E-22 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS09695 9be20e6fa6a3ceebd51d4ca3d7f1d163 321 Gene3D G3DSA:1.10.10.10 5 83 5.4E-27 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS09525 0865e889165e01127c869c913bcef3f9 455 SUPERFAMILY SSF55103 189 454 3.92E-63 T 10-11-2016 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 A4G23_RS09525 0865e889165e01127c869c913bcef3f9 455 Gene3D G3DSA:3.30.43.10 1 95 2.0E-23 T 10-11-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 A4G23_RS09525 0865e889165e01127c869c913bcef3f9 455 Pfam PF01565 FAD binding domain 40 179 8.0E-40 T 10-11-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 A4G23_RS09525 0865e889165e01127c869c913bcef3f9 455 Gene3D G3DSA:1.10.45.10 415 454 3.0E-14 T 10-11-2016 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 A4G23_RS09525 0865e889165e01127c869c913bcef3f9 455 Gene3D G3DSA:3.30.465.10 96 216 8.9E-45 T 10-11-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 A4G23_RS09525 0865e889165e01127c869c913bcef3f9 455 Pfam PF02913 FAD linked oxidases, C-terminal domain 217 454 2.4E-65 T 10-11-2016 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 A4G23_RS09525 0865e889165e01127c869c913bcef3f9 455 SUPERFAMILY SSF56176 1 216 7.94E-71 T 10-11-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 A4G23_RS20215 f5f5f9daa14aa8c851f745c04261e1c0 202 SUPERFAMILY SSF101874 29 200 1.96E-59 T 10-11-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like A4G23_RS20215 f5f5f9daa14aa8c851f745c04261e1c0 202 Pfam PF04264 YceI-like domain 31 197 1.6E-46 T 10-11-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like A4G23_RS20215 f5f5f9daa14aa8c851f745c04261e1c0 202 SMART SM00867 30 199 2.2E-76 T 10-11-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like A4G23_RS20215 f5f5f9daa14aa8c851f745c04261e1c0 202 Gene3D G3DSA:2.40.128.110 29 200 2.2E-63 T 10-11-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like A4G23_RS10445 f17a3aac6578f6958f93921e525d58f1 555 SMART SM00220 10 276 2.6E-57 T 10-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4G23_RS10445 f17a3aac6578f6958f93921e525d58f1 555 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 133 145 - T 10-11-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 A4G23_RS10445 f17a3aac6578f6958f93921e525d58f1 555 Gene3D G3DSA:1.10.510.10 80 269 1.7E-47 T 10-11-2016 A4G23_RS10445 f17a3aac6578f6958f93921e525d58f1 555 Gene3D G3DSA:1.25.40.10 368 527 2.3E-7 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS10445 f17a3aac6578f6958f93921e525d58f1 555 SUPERFAMILY SSF56112 4 323 2.13E-76 T 10-11-2016 IPR011009 Protein kinase-like domain A4G23_RS10445 f17a3aac6578f6958f93921e525d58f1 555 SUPERFAMILY SSF48452 414 527 8.41E-10 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS10445 f17a3aac6578f6958f93921e525d58f1 555 Gene3D G3DSA:3.30.200.20 3 79 1.4E-23 T 10-11-2016 A4G23_RS10445 f17a3aac6578f6958f93921e525d58f1 555 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 16 39 - T 10-11-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 A4G23_RS10445 f17a3aac6578f6958f93921e525d58f1 555 Pfam PF00069 Protein kinase domain 10 268 5.4E-44 T 10-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4G23_RS06265 f1c5b5d4b0dc3bb582be4d171dbc9ad1 561 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 64 556 33.081 T 10-11-2016 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 A4G23_RS06265 f1c5b5d4b0dc3bb582be4d171dbc9ad1 561 SUPERFAMILY SSF63418 82 166 1.26E-20 T 10-11-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 A4G23_RS06265 f1c5b5d4b0dc3bb582be4d171dbc9ad1 561 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 88 556 7.3E-145 T 10-11-2016 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 A4G23_RS06265 f1c5b5d4b0dc3bb582be4d171dbc9ad1 561 SUPERFAMILY SSF53623 168 398 7.2E-67 T 10-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4G23_RS06265 f1c5b5d4b0dc3bb582be4d171dbc9ad1 561 Gene3D G3DSA:3.40.1390.10 82 166 1.3E-21 T 10-11-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 A4G23_RS06265 f1c5b5d4b0dc3bb582be4d171dbc9ad1 561 Pfam PF08245 Mur ligase middle domain 177 378 1.1E-48 T 10-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4G23_RS06265 f1c5b5d4b0dc3bb582be4d171dbc9ad1 561 Pfam PF01225 Mur ligase family, catalytic domain 89 163 2.9E-12 T 10-11-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 A4G23_RS06265 f1c5b5d4b0dc3bb582be4d171dbc9ad1 561 Gene3D G3DSA:3.90.190.20 403 549 1.1E-48 T 10-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4G23_RS06265 f1c5b5d4b0dc3bb582be4d171dbc9ad1 561 Gene3D G3DSA:3.40.1190.10 171 402 2.6E-78 T 10-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4G23_RS06265 f1c5b5d4b0dc3bb582be4d171dbc9ad1 561 Pfam PF02875 Mur ligase family, glutamate ligase domain 399 483 6.0E-19 T 10-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4G23_RS06265 f1c5b5d4b0dc3bb582be4d171dbc9ad1 561 SUPERFAMILY SSF53244 399 558 6.54E-43 T 10-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4G23_RS18625 cc6fd77b952d027af4f6d5eb3abe14c5 286 SUPERFAMILY SSF89550 2 80 4.12E-44 T 10-11-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A4G23_RS18625 cc6fd77b952d027af4f6d5eb3abe14c5 286 SUPERFAMILY SSF89550 163 255 4.12E-44 T 10-11-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A4G23_RS18625 cc6fd77b952d027af4f6d5eb3abe14c5 286 Gene3D G3DSA:3.20.20.140 155 254 2.6E-36 T 10-11-2016 A4G23_RS18625 cc6fd77b952d027af4f6d5eb3abe14c5 286 Gene3D G3DSA:3.20.20.140 2 85 2.6E-36 T 10-11-2016 A4G23_RS18625 cc6fd77b952d027af4f6d5eb3abe14c5 286 Pfam PF02811 PHP domain 4 70 7.4E-8 T 10-11-2016 IPR004013 PHP domain GO:0003824 A4G23_RS18625 cc6fd77b952d027af4f6d5eb3abe14c5 286 SMART SM00481 3 67 8.9E-15 T 10-11-2016 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 A4G23_RS07525 b1ef9cd8fd0864c182e6ba8487f655c9 811 SUPERFAMILY SSF51445 2 312 2.63E-87 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS07525 b1ef9cd8fd0864c182e6ba8487f655c9 811 SUPERFAMILY SSF52279 546 703 7.98E-51 T 10-11-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 A4G23_RS07525 b1ef9cd8fd0864c182e6ba8487f655c9 811 SUPERFAMILY SSF52279 315 385 7.98E-51 T 10-11-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 A4G23_RS07525 b1ef9cd8fd0864c182e6ba8487f655c9 811 SMART SM01217 729 799 1.1E-17 T 10-11-2016 IPR026891 Fibronectin type III-like domain A4G23_RS07525 b1ef9cd8fd0864c182e6ba8487f655c9 811 Gene3D G3DSA:3.20.20.300 3 290 2.2E-92 T 10-11-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4G23_RS07525 b1ef9cd8fd0864c182e6ba8487f655c9 811 Pfam PF14310 Fibronectin type III-like domain 729 798 3.5E-16 T 10-11-2016 IPR026891 Fibronectin type III-like domain A4G23_RS07525 b1ef9cd8fd0864c182e6ba8487f655c9 811 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 316 700 9.5E-58 T 10-11-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 A4G23_RS07525 b1ef9cd8fd0864c182e6ba8487f655c9 811 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 53 280 5.5E-53 T 10-11-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4G23_RS07525 b1ef9cd8fd0864c182e6ba8487f655c9 811 PRINTS PR00133 Glycosyl hydrolase family 3 signature 65 84 7.5E-32 T 10-11-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4G23_RS07525 b1ef9cd8fd0864c182e6ba8487f655c9 811 PRINTS PR00133 Glycosyl hydrolase family 3 signature 142 158 7.5E-32 T 10-11-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4G23_RS07525 b1ef9cd8fd0864c182e6ba8487f655c9 811 PRINTS PR00133 Glycosyl hydrolase family 3 signature 111 127 7.5E-32 T 10-11-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4G23_RS07525 b1ef9cd8fd0864c182e6ba8487f655c9 811 PRINTS PR00133 Glycosyl hydrolase family 3 signature 212 230 7.5E-32 T 10-11-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4G23_RS07525 b1ef9cd8fd0864c182e6ba8487f655c9 811 PRINTS PR00133 Glycosyl hydrolase family 3 signature 36 52 7.5E-32 T 10-11-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4G23_RS07525 b1ef9cd8fd0864c182e6ba8487f655c9 811 Gene3D G3DSA:3.40.50.1700 304 388 1.1E-69 T 10-11-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 A4G23_RS07525 b1ef9cd8fd0864c182e6ba8487f655c9 811 Gene3D G3DSA:3.40.50.1700 546 702 1.1E-69 T 10-11-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 A4G23_RS22855 05cec23aff20bee7bbe13a3e7dcbce92 466 Gene3D G3DSA:3.40.190.10 175 374 3.0E-22 T 10-11-2016 A4G23_RS22855 05cec23aff20bee7bbe13a3e7dcbce92 466 SUPERFAMILY SSF53850 20 454 2.04E-36 T 10-11-2016 A4G23_RS22855 05cec23aff20bee7bbe13a3e7dcbce92 466 TIGRFAM TIGR03851 chitin_NgcE: carbohydrate ABC transporter, N-acetylglucosamine/diacetylchitobiose-binding protein 14 462 2.5E-173 T 10-11-2016 IPR022386 Carbohydrate ABC transporter, N-acetylglucosamine/diacetylchitobiose-binding A4G23_RS22855 05cec23aff20bee7bbe13a3e7dcbce92 466 Pfam PF01547 Bacterial extracellular solute-binding protein 69 366 5.1E-17 T 10-11-2016 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 A4G23_RS15330 14c3e00064b4ad851e8ae95eff9a03de 325 Gene3D G3DSA:3.40.190.120 163 260 1.2E-24 T 10-11-2016 A4G23_RS15330 14c3e00064b4ad851e8ae95eff9a03de 325 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 47 319 2.7E-48 T 10-11-2016 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 A4G23_RS15330 14c3e00064b4ad851e8ae95eff9a03de 325 SUPERFAMILY SSF53850 47 322 5.43E-43 T 10-11-2016 A4G23_RS15330 14c3e00064b4ad851e8ae95eff9a03de 325 Gene3D G3DSA:3.40.190.10 44 162 8.5E-40 T 10-11-2016 A4G23_RS15330 14c3e00064b4ad851e8ae95eff9a03de 325 Gene3D G3DSA:3.40.190.10 273 323 8.5E-40 T 10-11-2016 A4G23_RS13595 7d3e97a3c3ffa1248743c7c748beb84c 96 ProSitePatterns PS01048 Ribosomal protein S6 signature. 44 53 - T 10-11-2016 IPR020815 Ribosomal protein S6, conserved site GO:0003735|GO:0005840|GO:0006412|GO:0019843 A4G23_RS13595 7d3e97a3c3ffa1248743c7c748beb84c 96 Gene3D G3DSA:3.30.70.60 1 94 8.8E-36 T 10-11-2016 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 A4G23_RS13595 7d3e97a3c3ffa1248743c7c748beb84c 96 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 95 22.439 T 10-11-2016 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 A4G23_RS13595 7d3e97a3c3ffa1248743c7c748beb84c 96 SUPERFAMILY SSF54995 1 94 4.32E-33 T 10-11-2016 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS13595 7d3e97a3c3ffa1248743c7c748beb84c 96 Pfam PF01250 Ribosomal protein S6 3 92 2.6E-29 T 10-11-2016 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS13595 7d3e97a3c3ffa1248743c7c748beb84c 96 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 92 7.3E-27 T 10-11-2016 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS14470 2201ca5ba7e7e928a80b8194995bd23c 393 Gene3D G3DSA:3.90.1150.10 261 393 1.6E-31 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS14470 2201ca5ba7e7e928a80b8194995bd23c 393 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 117 138 9.9E-11 T 10-11-2016 A4G23_RS14470 2201ca5ba7e7e928a80b8194995bd23c 393 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 203 226 9.9E-11 T 10-11-2016 A4G23_RS14470 2201ca5ba7e7e928a80b8194995bd23c 393 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 167 191 9.9E-11 T 10-11-2016 A4G23_RS14470 2201ca5ba7e7e928a80b8194995bd23c 393 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 95 115 9.9E-11 T 10-11-2016 A4G23_RS14470 2201ca5ba7e7e928a80b8194995bd23c 393 Pfam PF00155 Aminotransferase class I and II 33 390 1.3E-66 T 10-11-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4G23_RS14470 2201ca5ba7e7e928a80b8194995bd23c 393 Gene3D G3DSA:3.40.640.10 46 260 3.5E-75 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS14470 2201ca5ba7e7e928a80b8194995bd23c 393 SUPERFAMILY SSF53383 9 392 6.12E-111 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS06910 bec2ffef5f28bfe99cec92eef1d6d23a 246 Pfam PF03713 Domain of unknown function (DUF305) 56 237 5.8E-47 T 10-11-2016 IPR005183 Domain of unknown function DUF305 A4G23_RS06910 bec2ffef5f28bfe99cec92eef1d6d23a 246 Gene3D G3DSA:1.20.1260.10 50 240 9.6E-61 T 10-11-2016 IPR012347 Ferritin-related A4G23_RS25880 d2cdb761be0e1334f6e375a50bfa9680 321 Pfam PF10017 Histidine-specific methyltransferase, SAM-dependent 191 315 1.4E-39 T 10-11-2016 IPR019257 Histidine-specific methyltransferase, SAM-dependent A4G23_RS25880 d2cdb761be0e1334f6e375a50bfa9680 321 Hamap MF_02037 Histidine N-alpha-methyltransferase [egtD]. 6 320 55.578 T 10-11-2016 IPR032888 Histidine N-alpha-methyltransferase, Actinobacteria-type GO:0008276|GO:0052699 KEGG: 00340+2.1.1.44|MetaCyc: PWY-7255|MetaCyc: PWY-7550 A4G23_RS25880 d2cdb761be0e1334f6e375a50bfa9680 321 SUPERFAMILY SSF53335 27 193 3.82E-15 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS25880 d2cdb761be0e1334f6e375a50bfa9680 321 SUPERFAMILY SSF53335 283 309 3.82E-15 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS25880 d2cdb761be0e1334f6e375a50bfa9680 321 TIGRFAM TIGR03438 egtD_ergothio: dimethylhistidine N-methyltransferase 19 317 6.2E-113 T 10-11-2016 IPR017804 Methyltransferase EgtD-like A4G23_RS25880 d2cdb761be0e1334f6e375a50bfa9680 321 PIRSF PIRSF018005 5 321 4.1E-134 T 10-11-2016 IPR017804 Methyltransferase EgtD-like A4G23_RS25880 d2cdb761be0e1334f6e375a50bfa9680 321 Gene3D G3DSA:3.40.50.150 51 247 1.5E-7 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS19570 6b484a1334f2bacfcfca895e5fb5336c 305 Gene3D G3DSA:1.10.287.80 245 291 9.9E-27 T 10-11-2016 A4G23_RS19570 6b484a1334f2bacfcfca895e5fb5336c 305 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 282 295 - T 10-11-2016 IPR023632 ATPase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210 A4G23_RS19570 6b484a1334f2bacfcfca895e5fb5336c 305 Pfam PF00231 ATP synthase 5 296 5.6E-85 T 10-11-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 A4G23_RS19570 6b484a1334f2bacfcfca895e5fb5336c 305 SUPERFAMILY SSF52943 3 296 1.7E-80 T 10-11-2016 IPR023633 ATPase, F1 complex, gamma subunit domain Reactome: R-HSA-163210 A4G23_RS19570 6b484a1334f2bacfcfca895e5fb5336c 305 Hamap MF_00815 ATP synthase gamma chain [atpG]. 2 296 33.327 T 10-11-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 A4G23_RS19570 6b484a1334f2bacfcfca895e5fb5336c 305 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 3 296 1.9E-93 T 10-11-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 A4G23_RS19570 6b484a1334f2bacfcfca895e5fb5336c 305 Gene3D G3DSA:1.10.287.80 211 244 1.1E-28 T 10-11-2016 A4G23_RS19570 6b484a1334f2bacfcfca895e5fb5336c 305 Gene3D G3DSA:1.10.287.80 20 61 1.1E-28 T 10-11-2016 A4G23_RS19570 6b484a1334f2bacfcfca895e5fb5336c 305 PRINTS PR00126 ATP synthase gamma subunit signature 171 188 6.9E-32 T 10-11-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 A4G23_RS19570 6b484a1334f2bacfcfca895e5fb5336c 305 PRINTS PR00126 ATP synthase gamma subunit signature 274 295 6.9E-32 T 10-11-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 A4G23_RS19570 6b484a1334f2bacfcfca895e5fb5336c 305 PRINTS PR00126 ATP synthase gamma subunit signature 74 93 6.9E-32 T 10-11-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 A4G23_RS19570 6b484a1334f2bacfcfca895e5fb5336c 305 PRINTS PR00126 ATP synthase gamma subunit signature 243 262 6.9E-32 T 10-11-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 A4G23_RS19570 6b484a1334f2bacfcfca895e5fb5336c 305 Gene3D G3DSA:3.40.1380.10 64 197 2.2E-38 T 10-11-2016 A4G23_RS16135 20e6a75c4ffabe73f9eb245f2a34403c 336 Gene3D G3DSA:1.10.600.10 16 334 6.5E-86 T 10-11-2016 IPR008949 Isoprenoid synthase domain A4G23_RS16135 20e6a75c4ffabe73f9eb245f2a34403c 336 SUPERFAMILY SSF48576 20 334 5.28E-81 T 10-11-2016 IPR008949 Isoprenoid synthase domain A4G23_RS16135 20e6a75c4ffabe73f9eb245f2a34403c 336 Pfam PF00348 Polyprenyl synthetase 42 261 6.0E-57 T 10-11-2016 IPR000092 Polyprenyl synthetase GO:0008299 A4G23_RS16135 20e6a75c4ffabe73f9eb245f2a34403c 336 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 212 224 - T 10-11-2016 IPR000092 Polyprenyl synthetase GO:0008299 A4G23_RS18910 d8162e4c5111c32d35824a2b0774b459 448 ProSitePatterns PS00104 EPSP synthase signature 1. 106 120 - T 10-11-2016 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 A4G23_RS18910 d8162e4c5111c32d35824a2b0774b459 448 ProSitePatterns PS00885 EPSP synthase signature 2. 359 377 - T 10-11-2016 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 A4G23_RS18910 d8162e4c5111c32d35824a2b0774b459 448 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 17 438 8.3E-108 T 10-11-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 A4G23_RS18910 d8162e4c5111c32d35824a2b0774b459 448 SUPERFAMILY SSF55205 17 442 4.45E-101 T 10-11-2016 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 A4G23_RS18910 d8162e4c5111c32d35824a2b0774b459 448 Gene3D G3DSA:3.65.10.10 30 258 2.4E-63 T 10-11-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 A4G23_RS18910 d8162e4c5111c32d35824a2b0774b459 448 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 18 446 28.765 T 10-11-2016 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 A4G23_RS18910 d8162e4c5111c32d35824a2b0774b459 448 Gene3D G3DSA:3.65.10.10 259 443 8.4E-55 T 10-11-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 A4G23_RS18910 d8162e4c5111c32d35824a2b0774b459 448 PIRSF PIRSF000505 9 447 3.3E-113 T 10-11-2016 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 A4G23_RS18910 d8162e4c5111c32d35824a2b0774b459 448 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 23 444 1.1E-110 T 10-11-2016 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 A4G23_RS14325 928a1aebff3aae48ac24409fe8479a15 194 Pfam PF02342 TerD domain 2 181 3.1E-43 T 10-11-2016 IPR003325 TerD domain GO:0006950 A4G23_RS14325 928a1aebff3aae48ac24409fe8479a15 194 Gene3D G3DSA:2.60.60.30 21 183 3.4E-46 T 10-11-2016 A4G23_RS19145 7f0f0eda3332db0c17ddc1b574ac3eb0 312 SUPERFAMILY SSF161098 66 267 5.1E-43 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS19145 7f0f0eda3332db0c17ddc1b574ac3eb0 312 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 279 2.2E-21 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS19145 7f0f0eda3332db0c17ddc1b574ac3eb0 312 Gene3D G3DSA:1.10.3720.10 64 281 6.3E-49 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS19145 7f0f0eda3332db0c17ddc1b574ac3eb0 312 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 68 176 1.6E-18 T 10-11-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 A4G23_RS19875 269ef584b4b68bbda671391335809ad0 736 Gene3D G3DSA:3.20.20.80 186 611 4.7E-123 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS19875 269ef584b4b68bbda671391335809ad0 736 SUPERFAMILY SSF81296 23 169 4.0E-36 T 10-11-2016 IPR014756 Immunoglobulin E-set A4G23_RS19875 269ef584b4b68bbda671391335809ad0 736 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 28 119 2.5E-19 T 10-11-2016 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 A4G23_RS19875 269ef584b4b68bbda671391335809ad0 736 SUPERFAMILY SSF51445 532 610 6.15E-133 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS19875 269ef584b4b68bbda671391335809ad0 736 SUPERFAMILY SSF51445 171 503 6.15E-133 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS19875 269ef584b4b68bbda671391335809ad0 736 SUPERFAMILY SSF51011 623 732 2.73E-18 T 10-11-2016 A4G23_RS19875 269ef584b4b68bbda671391335809ad0 736 Gene3D G3DSA:2.60.40.10 23 185 7.2E-48 T 10-11-2016 IPR013783 Immunoglobulin-like fold A4G23_RS19875 269ef584b4b68bbda671391335809ad0 736 Pfam PF00128 Alpha amylase, catalytic domain 225 311 9.3E-6 T 10-11-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A4G23_RS19875 269ef584b4b68bbda671391335809ad0 736 SMART SM00642 191 602 8.6E-8 T 10-11-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A4G23_RS19875 269ef584b4b68bbda671391335809ad0 736 Gene3D G3DSA:2.60.40.1180 622 733 2.1E-22 T 10-11-2016 IPR013780 Glycosyl hydrolase, all-beta A4G23_RS19875 269ef584b4b68bbda671391335809ad0 736 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 24 732 4.9E-303 T 10-11-2016 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 A4G23_RS26110 fc1a7b8519759ac50e546c0be62844e9 433 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 140 154 1.1E-8 T 10-11-2016 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 A4G23_RS26110 fc1a7b8519759ac50e546c0be62844e9 433 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 51 59 1.1E-8 T 10-11-2016 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 A4G23_RS26110 fc1a7b8519759ac50e546c0be62844e9 433 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 81 92 1.1E-8 T 10-11-2016 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 A4G23_RS26110 fc1a7b8519759ac50e546c0be62844e9 433 SUPERFAMILY SSF53474 15 297 1.77E-29 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS26110 fc1a7b8519759ac50e546c0be62844e9 433 Pfam PF00561 alpha/beta hydrolase fold 49 216 2.6E-15 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS26110 fc1a7b8519759ac50e546c0be62844e9 433 Gene3D G3DSA:3.40.50.1820 13 243 1.9E-54 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS26110 fc1a7b8519759ac50e546c0be62844e9 433 Gene3D G3DSA:3.40.50.1820 315 427 1.9E-54 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS24050 b552d4e273912f273f8f73b6f257678c 287 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 5.8E-20 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS24050 b552d4e273912f273f8f73b6f257678c 287 SUPERFAMILY SSF53850 89 285 1.71E-29 T 10-11-2016 A4G23_RS24050 b552d4e273912f273f8f73b6f257678c 287 Pfam PF03466 LysR substrate binding domain 90 282 3.6E-29 T 10-11-2016 IPR005119 LysR, substrate-binding A4G23_RS24050 b552d4e273912f273f8f73b6f257678c 287 Gene3D G3DSA:1.10.10.10 5 82 1.6E-22 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS24050 b552d4e273912f273f8f73b6f257678c 287 Gene3D G3DSA:3.40.190.10 176 255 2.1E-14 T 10-11-2016 A4G23_RS24050 b552d4e273912f273f8f73b6f257678c 287 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 8.3E-6 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS24050 b552d4e273912f273f8f73b6f257678c 287 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 8.3E-6 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS24050 b552d4e273912f273f8f73b6f257678c 287 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 8.3E-6 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS24050 b552d4e273912f273f8f73b6f257678c 287 SUPERFAMILY SSF46785 2 108 8.17E-19 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS24050 b552d4e273912f273f8f73b6f257678c 287 Gene3D G3DSA:3.40.190.10 89 175 2.6E-10 T 10-11-2016 A4G23_RS21635 d4f2a762749ddce73d37bff964d736cd 360 Gene3D G3DSA:3.30.1780.10 16 161 2.2E-30 T 10-11-2016 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 A4G23_RS21635 d4f2a762749ddce73d37bff964d736cd 360 SUPERFAMILY SSF51735 14 356 1.97E-54 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS21635 d4f2a762749ddce73d37bff964d736cd 360 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 85 345 5.0E-33 T 10-11-2016 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 A4G23_RS21635 d4f2a762749ddce73d37bff964d736cd 360 Gene3D G3DSA:3.40.50.720 162 323 6.9E-23 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS21635 d4f2a762749ddce73d37bff964d736cd 360 PIRSF PIRSF001439 10 356 5.6E-52 T 10-11-2016 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 A4G23_RS18100 8f1d7ec9a068ce08f60faf15f5c52188 409 SUPERFAMILY SSF52172 2 137 1.21E-8 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS18100 8f1d7ec9a068ce08f60faf15f5c52188 409 Gene3D G3DSA:3.40.50.2300 2 130 6.0E-8 T 10-11-2016 A4G23_RS18100 8f1d7ec9a068ce08f60faf15f5c52188 409 SUPERFAMILY SSF52540 152 387 6.89E-32 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS18100 8f1d7ec9a068ce08f60faf15f5c52188 409 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 154 335 3.6E-21 T 10-11-2016 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A4G23_RS18100 8f1d7ec9a068ce08f60faf15f5c52188 409 Gene3D G3DSA:3.40.50.300 151 387 8.1E-37 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS03635 8d90041d818a1c6500789c290de4960f 889 Pfam PF01411 tRNA synthetases class II (A) 5 564 1.3E-200 T 10-11-2016 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 A4G23_RS03635 8d90041d818a1c6500789c290de4960f 889 Gene3D G3DSA:3.30.930.10 1 244 1.2E-98 T 10-11-2016 A4G23_RS03635 8d90041d818a1c6500789c290de4960f 889 SUPERFAMILY SSF55186 561 720 3.14E-43 T 10-11-2016 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 A4G23_RS03635 8d90041d818a1c6500789c290de4960f 889 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 889 170.781 T 10-11-2016 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 A4G23_RS03635 8d90041d818a1c6500789c290de4960f 889 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 5 868 1.2E-262 T 10-11-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A4G23_RS03635 8d90041d818a1c6500789c290de4960f 889 SUPERFAMILY SSF101353 249 446 3.14E-61 T 10-11-2016 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 A4G23_RS03635 8d90041d818a1c6500789c290de4960f 889 PRINTS PR00980 Alanyl-tRNA synthetase signature 196 207 1.4E-28 T 10-11-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A4G23_RS03635 8d90041d818a1c6500789c290de4960f 889 PRINTS PR00980 Alanyl-tRNA synthetase signature 69 80 1.4E-28 T 10-11-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A4G23_RS03635 8d90041d818a1c6500789c290de4960f 889 PRINTS PR00980 Alanyl-tRNA synthetase signature 303 316 1.4E-28 T 10-11-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A4G23_RS03635 8d90041d818a1c6500789c290de4960f 889 PRINTS PR00980 Alanyl-tRNA synthetase signature 229 242 1.4E-28 T 10-11-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A4G23_RS03635 8d90041d818a1c6500789c290de4960f 889 PRINTS PR00980 Alanyl-tRNA synthetase signature 279 295 1.4E-28 T 10-11-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A4G23_RS03635 8d90041d818a1c6500789c290de4960f 889 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 662 705 3.8E-18 T 10-11-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 A4G23_RS03635 8d90041d818a1c6500789c290de4960f 889 Pfam PF02272 DHHA1 domain 813 882 1.9E-10 T 10-11-2016 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A4G23_RS03635 8d90041d818a1c6500789c290de4960f 889 SMART SM00863 662 705 2.3E-21 T 10-11-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 A4G23_RS03635 8d90041d818a1c6500789c290de4960f 889 SUPERFAMILY SSF55681 2 248 1.37E-92 T 10-11-2016 A4G23_RS03635 8d90041d818a1c6500789c290de4960f 889 SUPERFAMILY SSF50447 461 560 5.65E-18 T 10-11-2016 IPR009000 Translation protein, beta-barrel domain A4G23_RS02300 8f05c32ccfe41af1ed828f0e7e8ce504 339 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 10-11-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4G23_RS02300 8f05c32ccfe41af1ed828f0e7e8ce504 339 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 2 322 2.6E-132 T 10-11-2016 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 A4G23_RS02300 8f05c32ccfe41af1ed828f0e7e8ce504 339 Gene3D G3DSA:3.90.25.10 186 321 1.2E-48 T 10-11-2016 A4G23_RS02300 8f05c32ccfe41af1ed828f0e7e8ce504 339 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 307 1.8E-79 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS02300 8f05c32ccfe41af1ed828f0e7e8ce504 339 Gene3D G3DSA:3.40.50.720 1 185 7.0E-66 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS02300 8f05c32ccfe41af1ed828f0e7e8ce504 339 SUPERFAMILY SSF51735 1 323 2.7E-98 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS00200 1dee2aaae3e31f75d0de165465264911 120 Gene3D G3DSA:3.40.250.10 8 109 6.4E-28 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS00200 1dee2aaae3e31f75d0de165465264911 120 Pfam PF00581 Rhodanese-like domain 14 104 1.4E-12 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS00200 1dee2aaae3e31f75d0de165465264911 120 SUPERFAMILY SSF52821 6 112 2.1E-30 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS00200 1dee2aaae3e31f75d0de165465264911 120 SMART SM00450 12 108 3.7E-22 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS02275 2e106f8cd835ef8684801f354924c1b6 368 SUPERFAMILY SSF54197 199 358 1.68E-30 T 10-11-2016 IPR011146 HIT-like domain GO:0003824 A4G23_RS02275 2e106f8cd835ef8684801f354924c1b6 368 SUPERFAMILY SSF54197 42 197 8.29E-47 T 10-11-2016 IPR011146 HIT-like domain GO:0003824 A4G23_RS02275 2e106f8cd835ef8684801f354924c1b6 368 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 43 196 2.5E-32 T 10-11-2016 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 A4G23_RS02275 2e106f8cd835ef8684801f354924c1b6 368 TIGRFAM TIGR00209 galT_1: galactose-1-phosphate uridylyltransferase 44 357 1.4E-42 T 10-11-2016 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0006012|GO:0008108|GO:0008270 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 A4G23_RS02275 2e106f8cd835ef8684801f354924c1b6 368 Gene3D G3DSA:3.30.428.10 196 357 1.1E-42 T 10-11-2016 IPR011146 HIT-like domain GO:0003824 A4G23_RS02275 2e106f8cd835ef8684801f354924c1b6 368 PIRSF PIRSF000808 36 360 6.6E-96 T 10-11-2016 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0006012|GO:0008108|GO:0008270 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 A4G23_RS02275 2e106f8cd835ef8684801f354924c1b6 368 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 221 334 9.1E-13 T 10-11-2016 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 A4G23_RS02275 2e106f8cd835ef8684801f354924c1b6 368 ProSitePatterns PS00117 Galactose-1-phosphate uridyl transferase family 1 active site signature. 171 188 - T 10-11-2016 IPR019779 Galactose-1-phosphate uridyl transferase, class I His-active site GO:0006012|GO:0008108|GO:0008270 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 A4G23_RS02275 2e106f8cd835ef8684801f354924c1b6 368 Gene3D G3DSA:3.30.428.10 68 194 1.2E-36 T 10-11-2016 IPR011146 HIT-like domain GO:0003824 A4G23_RS13345 29cf869a10e957c48f441ca66a349c6c 486 Gene3D G3DSA:3.90.1310.10 74 143 1.2E-6 T 10-11-2016 A4G23_RS13345 29cf869a10e957c48f441ca66a349c6c 486 Gene3D G3DSA:3.40.710.10 144 484 2.9E-99 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS13345 29cf869a10e957c48f441ca66a349c6c 486 SUPERFAMILY SSF56601 140 483 5.12E-88 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS13345 29cf869a10e957c48f441ca66a349c6c 486 Pfam PF00905 Penicillin binding protein transpeptidase domain 156 479 1.0E-70 T 10-11-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A4G23_RS05125 2c159e5d14e9f9e4b71e530d4ef4933b 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 1.6E-46 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS05125 2c159e5d14e9f9e4b71e530d4ef4933b 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 1.6E-46 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS05125 2c159e5d14e9f9e4b71e530d4ef4933b 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 219 1.6E-46 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS05125 2c159e5d14e9f9e4b71e530d4ef4933b 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 164 1.6E-46 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS05125 2c159e5d14e9f9e4b71e530d4ef4933b 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 1.6E-46 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS05125 2c159e5d14e9f9e4b71e530d4ef4933b 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.6E-46 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS05125 2c159e5d14e9f9e4b71e530d4ef4933b 239 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 5 235 9.8E-97 T 10-11-2016 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 A4G23_RS05125 2c159e5d14e9f9e4b71e530d4ef4933b 239 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 181 2.3E-9 T 10-11-2016 A4G23_RS05125 2c159e5d14e9f9e4b71e530d4ef4933b 239 SUPERFAMILY SSF51735 3 235 5.39E-84 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS05125 2c159e5d14e9f9e4b71e530d4ef4933b 239 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 132 160 - T 10-11-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4G23_RS05125 2c159e5d14e9f9e4b71e530d4ef4933b 239 Gene3D G3DSA:3.40.50.720 3 235 5.8E-86 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS05125 2c159e5d14e9f9e4b71e530d4ef4933b 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 72 83 5.3E-12 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS05125 2c159e5d14e9f9e4b71e530d4ef4933b 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 164 5.3E-12 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS05125 2c159e5d14e9f9e4b71e530d4ef4933b 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 125 133 5.3E-12 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS05125 2c159e5d14e9f9e4b71e530d4ef4933b 239 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 235 4.4E-66 T 10-11-2016 A4G23_RS22915 3762e36ce797802b73d1bbf68426820e 408 Pfam PF02803 Thiolase, C-terminal domain 275 397 7.8E-36 T 10-11-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 A4G23_RS22915 3762e36ce797802b73d1bbf68426820e 408 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 11 397 3.4E-132 T 10-11-2016 IPR002155 Thiolase GO:0008152|GO:0016747 A4G23_RS22915 3762e36ce797802b73d1bbf68426820e 408 SUPERFAMILY SSF53901 7 272 3.26E-62 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS22915 3762e36ce797802b73d1bbf68426820e 408 PIRSF PIRSF000429 3 400 2.6E-123 T 10-11-2016 IPR002155 Thiolase GO:0008152|GO:0016747 A4G23_RS22915 3762e36ce797802b73d1bbf68426820e 408 Gene3D G3DSA:3.40.47.10 152 191 3.1E-50 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS22915 3762e36ce797802b73d1bbf68426820e 408 Gene3D G3DSA:3.40.47.10 280 398 3.1E-50 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS22915 3762e36ce797802b73d1bbf68426820e 408 Pfam PF00108 Thiolase, N-terminal domain 8 266 2.5E-60 T 10-11-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 A4G23_RS22915 3762e36ce797802b73d1bbf68426820e 408 SUPERFAMILY SSF53901 277 397 3.91E-38 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS22915 3762e36ce797802b73d1bbf68426820e 408 ProSitePatterns PS00737 Thiolases signature 2. 344 360 - T 10-11-2016 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 A4G23_RS22915 3762e36ce797802b73d1bbf68426820e 408 Gene3D G3DSA:3.40.47.10 192 278 3.2E-53 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS22915 3762e36ce797802b73d1bbf68426820e 408 Gene3D G3DSA:3.40.47.10 7 131 3.2E-53 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS13130 eb03d5461738446d0d6094406b5430a4 613 Pfam PF00578 AhpC/TSA family 19 140 1.3E-11 T 10-11-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A4G23_RS13130 eb03d5461738446d0d6094406b5430a4 613 Gene3D G3DSA:2.120.10.30 184 480 2.3E-46 T 10-11-2016 IPR011042 Six-bladed beta-propeller, TolB-like A4G23_RS13130 eb03d5461738446d0d6094406b5430a4 613 Gene3D G3DSA:3.40.30.10 20 163 7.7E-42 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS13130 eb03d5461738446d0d6094406b5430a4 613 Pfam PF01436 NHL repeat 240 264 3.8E-6 T 10-11-2016 IPR001258 NHL repeat GO:0005515 A4G23_RS13130 eb03d5461738446d0d6094406b5430a4 613 SUPERFAMILY SSF101898 174 478 9.94E-38 T 10-11-2016 A4G23_RS13130 eb03d5461738446d0d6094406b5430a4 613 SUPERFAMILY SSF52833 31 173 3.02E-32 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS18205 e80cec99ee99f1e5fddbca99053b66f5 322 Gene3D G3DSA:3.40.190.10 103 187 3.4E-19 T 10-11-2016 A4G23_RS18205 e80cec99ee99f1e5fddbca99053b66f5 322 SUPERFAMILY SSF46785 10 123 1.88E-24 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS18205 e80cec99ee99f1e5fddbca99053b66f5 322 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 52 63 2.1E-7 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS18205 e80cec99ee99f1e5fddbca99053b66f5 322 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 52 2.1E-7 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS18205 e80cec99ee99f1e5fddbca99053b66f5 322 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 42 2.1E-7 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS18205 e80cec99ee99f1e5fddbca99053b66f5 322 SUPERFAMILY SSF53850 102 313 4.34E-38 T 10-11-2016 A4G23_RS18205 e80cec99ee99f1e5fddbca99053b66f5 322 Gene3D G3DSA:1.10.10.10 15 98 1.6E-24 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS18205 e80cec99ee99f1e5fddbca99053b66f5 322 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 16 75 2.9E-19 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS18205 e80cec99ee99f1e5fddbca99053b66f5 322 Pfam PF03466 LysR substrate binding domain 101 309 7.8E-44 T 10-11-2016 IPR005119 LysR, substrate-binding A4G23_RS18205 e80cec99ee99f1e5fddbca99053b66f5 322 Gene3D G3DSA:3.40.190.10 188 283 1.5E-27 T 10-11-2016 A4G23_RS05085 771ebb09c408b384438f25e97a1b0b8f 402 Gene3D G3DSA:1.10.150.210 193 244 1.2E-25 T 10-11-2016 IPR023190 Phosphoserine phosphatase, domain 2 GO:0004647|GO:0006564 KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3|Reactome: R-HSA-977347 A4G23_RS05085 771ebb09c408b384438f25e97a1b0b8f 402 SUPERFAMILY SSF56784 182 389 2.03E-47 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS05085 771ebb09c408b384438f25e97a1b0b8f 402 Gene3D G3DSA:3.30.70.260 11 89 2.6E-15 T 10-11-2016 A4G23_RS05085 771ebb09c408b384438f25e97a1b0b8f 402 Gene3D G3DSA:3.30.70.260 115 182 6.1E-4 T 10-11-2016 A4G23_RS05085 771ebb09c408b384438f25e97a1b0b8f 402 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 169 386 3.4E-77 T 10-11-2016 A4G23_RS05085 771ebb09c408b384438f25e97a1b0b8f 402 Gene3D G3DSA:3.40.50.1000 245 373 1.9E-45 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS05085 771ebb09c408b384438f25e97a1b0b8f 402 Pfam PF12710 haloacid dehalogenase-like hydrolase 184 351 2.5E-23 T 10-11-2016 A4G23_RS05085 771ebb09c408b384438f25e97a1b0b8f 402 Pfam PF13740 ACT domain 11 84 4.1E-16 T 10-11-2016 A4G23_RS05085 771ebb09c408b384438f25e97a1b0b8f 402 SUPERFAMILY SSF55021 12 83 6.7E-9 T 10-11-2016 A4G23_RS05085 771ebb09c408b384438f25e97a1b0b8f 402 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 183 353 1.7E-27 T 10-11-2016 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 A4G23_RS20040 5e40fb1074b509a241acc524ab0b044a 377 SUPERFAMILY SSF52402 10 253 9.04E-46 T 10-11-2016 A4G23_RS20040 5e40fb1074b509a241acc524ab0b044a 377 Gene3D G3DSA:2.30.30.280 223 284 1.0E-14 T 10-11-2016 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 Reactome: R-HSA-6787450 A4G23_RS20040 5e40fb1074b509a241acc524ab0b044a 377 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 11 363 7.4E-86 T 10-11-2016 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 A4G23_RS20040 5e40fb1074b509a241acc524ab0b044a 377 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 9 364 36.055 T 10-11-2016 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 A4G23_RS20040 5e40fb1074b509a241acc524ab0b044a 377 Gene3D G3DSA:3.40.50.620 4 220 3.1E-77 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS20040 5e40fb1074b509a241acc524ab0b044a 377 Pfam PF03054 tRNA methyl transferase 10 363 6.9E-117 T 10-11-2016 A4G23_RS20040 5e40fb1074b509a241acc524ab0b044a 377 Gene3D G3DSA:2.40.30.10 290 369 4.1E-19 T 10-11-2016 A4G23_RS23595 0be424b71945c6fbddd9a7b2df0c9e6c 440 SUPERFAMILY SSF88659 283 337 2.88E-6 T 10-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS23595 0be424b71945c6fbddd9a7b2df0c9e6c 440 Gene3D G3DSA:1.10.1740.10 199 267 1.8E-6 T 10-11-2016 A4G23_RS23595 0be424b71945c6fbddd9a7b2df0c9e6c 440 SUPERFAMILY SSF88946 197 263 3.26E-6 T 10-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS23595 0be424b71945c6fbddd9a7b2df0c9e6c 440 Gene3D G3DSA:1.10.10.10 283 338 6.1E-8 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS23215 76f97fe0a43c7e6dd1b9c10ac409c15a 560 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 409 428 - T 10-11-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A4G23_RS23215 76f97fe0a43c7e6dd1b9c10ac409c15a 560 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 286 450 3.0E-26 T 10-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4G23_RS23215 76f97fe0a43c7e6dd1b9c10ac409c15a 560 Gene3D G3DSA:2.40.110.10 181 273 1.3E-20 T 10-11-2016 A4G23_RS23215 76f97fe0a43c7e6dd1b9c10ac409c15a 560 SUPERFAMILY SSF47203 291 453 1.93E-39 T 10-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4G23_RS23215 76f97fe0a43c7e6dd1b9c10ac409c15a 560 Gene3D G3DSA:1.20.140.10 274 455 3.0E-39 T 10-11-2016 A4G23_RS23215 76f97fe0a43c7e6dd1b9c10ac409c15a 560 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 183 195 - T 10-11-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A4G23_RS23215 76f97fe0a43c7e6dd1b9c10ac409c15a 560 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 181 276 5.4E-16 T 10-11-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 A4G23_RS23215 76f97fe0a43c7e6dd1b9c10ac409c15a 560 SUPERFAMILY SSF56645 59 283 2.54E-34 T 10-11-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 A4G23_RS15245 976ac4f70ea366e37becd33a0cdc42a3 164 Gene3D G3DSA:3.90.80.10 2 159 1.3E-53 T 10-11-2016 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 A4G23_RS15245 976ac4f70ea366e37becd33a0cdc42a3 164 SUPERFAMILY SSF50324 3 158 1.11E-57 T 10-11-2016 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 A4G23_RS15245 976ac4f70ea366e37becd33a0cdc42a3 164 Pfam PF00719 Inorganic pyrophosphatase 5 157 6.1E-52 T 10-11-2016 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 A4G23_RS15245 976ac4f70ea366e37becd33a0cdc42a3 164 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 52 58 - T 10-11-2016 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 A4G23_RS15245 976ac4f70ea366e37becd33a0cdc42a3 164 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 1 158 32.677 T 10-11-2016 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 A4G23_RS09580 960e09726572da5a9909d86d5ab1a017 83 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 72 1.6E-12 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS09580 960e09726572da5a9909d86d5ab1a017 83 SUPERFAMILY SSF46785 1 75 3.54E-17 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS09580 960e09726572da5a9909d86d5ab1a017 83 Gene3D G3DSA:1.10.10.10 2 73 5.9E-20 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS09580 960e09726572da5a9909d86d5ab1a017 83 SMART SM00345 13 72 5.3E-11 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS14690 f34b3e8757fa8426c7c6b8cde727e21c 252 Pfam PF05175 Methyltransferase small domain 66 182 7.3E-10 T 10-11-2016 IPR007848 Methyltransferase small domain GO:0008168 A4G23_RS14690 f34b3e8757fa8426c7c6b8cde727e21c 252 TIGRFAM TIGR03704 PrmC_rel_meth: putative protein-(glutamine-N5) methyltransferase, unknown substrate-specific 1 248 6.6E-114 T 10-11-2016 IPR022446 Conserved hypothetical protein CHP03704, protein-(glutamine-N5) methyltransferase A4G23_RS14690 f34b3e8757fa8426c7c6b8cde727e21c 252 Gene3D G3DSA:3.40.50.150 57 237 1.9E-42 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS14690 f34b3e8757fa8426c7c6b8cde727e21c 252 SUPERFAMILY SSF53335 33 214 1.91E-40 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS14690 f34b3e8757fa8426c7c6b8cde727e21c 252 Gene3D G3DSA:1.10.8.10 25 55 3.0E-5 T 10-11-2016 A4G23_RS14080 28b76f577142c5d521e21675fa66c77c 131 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 2 119 17.779 T 10-11-2016 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 A4G23_RS14080 28b76f577142c5d521e21675fa66c77c 131 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 4 112 3.8E-22 T 10-11-2016 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 A4G23_RS01780 242c8eefb096076fa5e3fe900c9fcf38 305 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 30 44 1.1E-9 T 10-11-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A4G23_RS01780 242c8eefb096076fa5e3fe900c9fcf38 305 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 44 62 1.1E-9 T 10-11-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A4G23_RS01780 242c8eefb096076fa5e3fe900c9fcf38 305 ProSitePatterns PS00894 DeoR-type HTH domain signature. 12 46 - T 10-11-2016 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 A4G23_RS01780 242c8eefb096076fa5e3fe900c9fcf38 305 Gene3D G3DSA:1.10.10.10 11 63 9.7E-12 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS01780 242c8eefb096076fa5e3fe900c9fcf38 305 SMART SM00420 12 64 1.0E-18 T 10-11-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A4G23_RS01780 242c8eefb096076fa5e3fe900c9fcf38 305 Pfam PF08220 DeoR-like helix-turn-helix domain 12 63 3.4E-17 T 10-11-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A4G23_RS01780 242c8eefb096076fa5e3fe900c9fcf38 305 Pfam PF00455 DeoR C terminal sensor domain 85 251 4.7E-51 T 10-11-2016 IPR014036 DeoR C-terminal sensor domain A4G23_RS01780 242c8eefb096076fa5e3fe900c9fcf38 305 Gene3D G3DSA:3.40.50.1360 169 234 5.3E-15 T 10-11-2016 A4G23_RS01780 242c8eefb096076fa5e3fe900c9fcf38 305 Gene3D G3DSA:3.40.50.1360 85 137 5.3E-15 T 10-11-2016 A4G23_RS01780 242c8eefb096076fa5e3fe900c9fcf38 305 SUPERFAMILY SSF46785 10 66 6.19E-13 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS01780 242c8eefb096076fa5e3fe900c9fcf38 305 SUPERFAMILY SSF100950 85 139 1.42E-30 T 10-11-2016 A4G23_RS01780 242c8eefb096076fa5e3fe900c9fcf38 305 SUPERFAMILY SSF100950 171 251 1.42E-30 T 10-11-2016 A4G23_RS01780 242c8eefb096076fa5e3fe900c9fcf38 305 SMART SM01134 80 252 3.7E-60 T 10-11-2016 A4G23_RS22415 0ddcdfe6f5684b774b2fe9b161c4c92a 242 Gene3D G3DSA:1.25.40.10 153 217 4.3E-5 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS22415 0ddcdfe6f5684b774b2fe9b161c4c92a 242 SUPERFAMILY SSF46894 2 91 2.78E-14 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS22415 0ddcdfe6f5684b774b2fe9b161c4c92a 242 SMART SM00862 14 92 3.2E-7 T 10-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4G23_RS22415 0ddcdfe6f5684b774b2fe9b161c4c92a 242 Pfam PF00486 Transcriptional regulatory protein, C terminal 23 90 8.2E-9 T 10-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4G23_RS22415 0ddcdfe6f5684b774b2fe9b161c4c92a 242 Gene3D G3DSA:1.10.10.10 17 92 6.0E-10 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS22415 0ddcdfe6f5684b774b2fe9b161c4c92a 242 SMART SM01043 99 239 1.9E-44 T 10-11-2016 IPR005158 Bacterial transcriptional activator domain A4G23_RS22415 0ddcdfe6f5684b774b2fe9b161c4c92a 242 Pfam PF03704 Bacterial transcriptional activator domain 99 239 4.4E-38 T 10-11-2016 IPR005158 Bacterial transcriptional activator domain A4G23_RS22415 0ddcdfe6f5684b774b2fe9b161c4c92a 242 SUPERFAMILY SSF48452 96 242 4.14E-32 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS22925 912171e90a2861524c2052e0f0aff436 748 PRINTS PR00067 Catalase signature 386 412 4.9E-69 T 10-11-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 A4G23_RS22925 912171e90a2861524c2052e0f0aff436 748 PRINTS PR00067 Catalase signature 82 105 4.9E-69 T 10-11-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 A4G23_RS22925 912171e90a2861524c2052e0f0aff436 748 PRINTS PR00067 Catalase signature 354 381 4.9E-69 T 10-11-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 A4G23_RS22925 912171e90a2861524c2052e0f0aff436 748 PRINTS PR00067 Catalase signature 165 182 4.9E-69 T 10-11-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 A4G23_RS22925 912171e90a2861524c2052e0f0aff436 748 PRINTS PR00067 Catalase signature 144 162 4.9E-69 T 10-11-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 A4G23_RS22925 912171e90a2861524c2052e0f0aff436 748 PRINTS PR00067 Catalase signature 184 202 4.9E-69 T 10-11-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 A4G23_RS22925 912171e90a2861524c2052e0f0aff436 748 Gene3D G3DSA:3.40.50.880 580 743 1.2E-36 T 10-11-2016 IPR029062 Class I glutamine amidotransferase-like A4G23_RS22925 912171e90a2861524c2052e0f0aff436 748 Pfam PF00199 Catalase 69 454 1.5E-161 T 10-11-2016 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 A4G23_RS22925 912171e90a2861524c2052e0f0aff436 748 Gene3D G3DSA:2.40.180.10 58 424 1.8E-165 T 10-11-2016 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 A4G23_RS22925 912171e90a2861524c2052e0f0aff436 748 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 399 407 - T 10-11-2016 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 A4G23_RS22925 912171e90a2861524c2052e0f0aff436 748 SMART SM01060 69 457 3.0E-246 T 10-11-2016 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 A4G23_RS22925 912171e90a2861524c2052e0f0aff436 748 Pfam PF06628 Catalase-related immune-responsive 486 549 1.3E-21 T 10-11-2016 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 A4G23_RS22925 912171e90a2861524c2052e0f0aff436 748 SUPERFAMILY SSF56634 58 571 3.14E-202 T 10-11-2016 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 A4G23_RS22925 912171e90a2861524c2052e0f0aff436 748 SUPERFAMILY SSF52317 580 740 7.79E-11 T 10-11-2016 IPR029062 Class I glutamine amidotransferase-like A4G23_RS22925 912171e90a2861524c2052e0f0aff436 748 ProSitePatterns PS00438 Catalase proximal active site signature. 105 121 - T 10-11-2016 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 A4G23_RS22925 912171e90a2861524c2052e0f0aff436 748 PIRSF PIRSF038927 40 745 3.0E-285 T 10-11-2016 IPR024712 Catalase, mono-functional, haem-containing, clade 2 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 A4G23_RS11950 d950b5b4d8a4e617a0f8e3cd00f8b021 151 SMART SM00347 35 135 4.6E-21 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS11950 d950b5b4d8a4e617a0f8e3cd00f8b021 151 Gene3D G3DSA:1.10.10.10 10 141 2.1E-32 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS11950 d950b5b4d8a4e617a0f8e3cd00f8b021 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 95 111 1.1E-5 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS11950 d950b5b4d8a4e617a0f8e3cd00f8b021 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 76 91 1.1E-5 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS11950 d950b5b4d8a4e617a0f8e3cd00f8b021 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 59 75 1.1E-5 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS11950 d950b5b4d8a4e617a0f8e3cd00f8b021 151 Pfam PF12802 MarR family 42 99 1.3E-14 T 10-11-2016 A4G23_RS11950 d950b5b4d8a4e617a0f8e3cd00f8b021 151 ProSitePatterns PS01117 MarR-type HTH domain signature. 74 108 - T 10-11-2016 IPR023187 Transcriptional regulator MarR-type, conserved site A4G23_RS11950 d950b5b4d8a4e617a0f8e3cd00f8b021 151 SUPERFAMILY SSF46785 10 142 6.27E-30 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS19580 c34fb143f2e67d896155d523db82cbb5 124 Gene3D G3DSA:2.60.15.10 4 91 7.7E-27 T 10-11-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 A4G23_RS19580 c34fb143f2e67d896155d523db82cbb5 124 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 5 83 2.3E-25 T 10-11-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 A4G23_RS19580 c34fb143f2e67d896155d523db82cbb5 124 SUPERFAMILY SSF51344 5 86 3.01E-22 T 10-11-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 A4G23_RS19580 c34fb143f2e67d896155d523db82cbb5 124 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 5 118 6.7E-28 T 10-11-2016 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 A4G23_RS19580 c34fb143f2e67d896155d523db82cbb5 124 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 3 120 19.104 T 10-11-2016 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 A4G23_RS19580 c34fb143f2e67d896155d523db82cbb5 124 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 18 78 1.0E-26 T 10-11-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 A4G23_RS15275 3fd50c01461f731c95537cdd7331be18 201 Pfam PF01227 GTP cyclohydrolase I 23 198 1.4E-76 T 10-11-2016 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 A4G23_RS15275 3fd50c01461f731c95537cdd7331be18 201 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 17 199 41.589 T 10-11-2016 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 A4G23_RS15275 3fd50c01461f731c95537cdd7331be18 201 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 127 137 - T 10-11-2016 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 A4G23_RS15275 3fd50c01461f731c95537cdd7331be18 201 Gene3D G3DSA:1.10.286.10 16 67 4.1E-24 T 10-11-2016 A4G23_RS15275 3fd50c01461f731c95537cdd7331be18 201 SUPERFAMILY SSF55620 14 198 9.64E-76 T 10-11-2016 A4G23_RS15275 3fd50c01461f731c95537cdd7331be18 201 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 77 93 - T 10-11-2016 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 A4G23_RS15275 3fd50c01461f731c95537cdd7331be18 201 Gene3D G3DSA:3.30.1130.10 70 199 3.6E-59 T 10-11-2016 A4G23_RS15275 3fd50c01461f731c95537cdd7331be18 201 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 24 198 6.9E-72 T 10-11-2016 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 A4G23_RS10030 ae95d9e49006906b0577d3af2da361fb 489 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 354 448 2.3E-12 T 10-11-2016 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain A4G23_RS10030 ae95d9e49006906b0577d3af2da361fb 489 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 78 239 7.4E-42 T 10-11-2016 IPR004474 Cell envelope-related transcriptional attenuator domain A4G23_RS10030 ae95d9e49006906b0577d3af2da361fb 489 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 77 239 1.5E-35 T 10-11-2016 IPR004474 Cell envelope-related transcriptional attenuator domain A4G23_RS20050 0a0a22e0c44e3e65cabaebc3f116df33 238 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2 177 1.8E-4 T 10-11-2016 A4G23_RS20050 0a0a22e0c44e3e65cabaebc3f116df33 238 Gene3D G3DSA:3.40.50.720 4 216 1.8E-54 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS20050 0a0a22e0c44e3e65cabaebc3f116df33 238 Pfam PF00106 short chain dehydrogenase 5 189 1.2E-40 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS20050 0a0a22e0c44e3e65cabaebc3f116df33 238 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 131 159 - T 10-11-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4G23_RS20050 0a0a22e0c44e3e65cabaebc3f116df33 238 SUPERFAMILY SSF51735 3 216 2.01E-53 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS20050 0a0a22e0c44e3e65cabaebc3f116df33 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 163 6.4E-20 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS20050 0a0a22e0c44e3e65cabaebc3f116df33 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 134 6.4E-20 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS20050 0a0a22e0c44e3e65cabaebc3f116df33 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 6.4E-20 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS20050 0a0a22e0c44e3e65cabaebc3f116df33 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 6.4E-20 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS20050 0a0a22e0c44e3e65cabaebc3f116df33 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 6.4E-20 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS11600 19c5f5bfb7e12423ed19efc50c0cbd84 262 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 100 247 2.4E-29 T 10-11-2016 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 A4G23_RS11600 19c5f5bfb7e12423ed19efc50c0cbd84 262 Pfam PF00440 Bacterial regulatory proteins, tetR family 44 87 4.4E-8 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS11600 19c5f5bfb7e12423ed19efc50c0cbd84 262 SUPERFAMILY SSF48498 106 249 1.07E-25 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS11600 19c5f5bfb7e12423ed19efc50c0cbd84 262 Gene3D G3DSA:1.10.357.10 29 252 5.8E-61 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS11600 19c5f5bfb7e12423ed19efc50c0cbd84 262 SUPERFAMILY SSF46689 32 94 7.48E-13 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS21035 810d92448344b70e98d738d0dcaad073 561 PIRSF PIRSF004803 12 561 1.8E-207 T 10-11-2016 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 A4G23_RS21035 810d92448344b70e98d738d0dcaad073 561 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 20 558 2.9E-151 T 10-11-2016 IPR004613 Ribonuclease J GO:0003723|GO:0046872 A4G23_RS21035 810d92448344b70e98d738d0dcaad073 561 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 370 412 5.0E-10 T 10-11-2016 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain A4G23_RS21035 810d92448344b70e98d738d0dcaad073 561 Pfam PF00753 Metallo-beta-lactamase superfamily 28 174 1.2E-12 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS21035 810d92448344b70e98d738d0dcaad073 561 Gene3D G3DSA:3.60.15.10 18 265 2.9E-75 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS21035 810d92448344b70e98d738d0dcaad073 561 SUPERFAMILY SSF56281 19 433 1.97E-96 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS21035 810d92448344b70e98d738d0dcaad073 561 Hamap MF_01491 Ribonuclease J [rnj]. 14 561 41.193 T 10-11-2016 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 A4G23_RS21035 810d92448344b70e98d738d0dcaad073 561 SMART SM00849 31 217 1.8E-21 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS05985 f6ccc6064798e5ca7676a419062eac09 271 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 52 65 - T 10-11-2016 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A4G23_RS05985 f6ccc6064798e5ca7676a419062eac09 271 SUPERFAMILY SSF51366 8 246 4.52E-79 T 10-11-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 A4G23_RS05985 f6ccc6064798e5ca7676a419062eac09 271 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 18 266 34.849 T 10-11-2016 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A4G23_RS05985 f6ccc6064798e5ca7676a419062eac09 271 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 15 263 8.5E-69 T 10-11-2016 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A4G23_RS05985 f6ccc6064798e5ca7676a419062eac09 271 Pfam PF00290 Tryptophan synthase alpha chain 13 264 9.1E-79 T 10-11-2016 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A4G23_RS05985 f6ccc6064798e5ca7676a419062eac09 271 Gene3D G3DSA:3.20.20.70 9 269 4.4E-93 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS22140 6dadc0999caac420bf85e2de87c78338 348 Gene3D G3DSA:1.10.3470.10 8 341 3.6E-105 T 10-11-2016 IPR029022 ABC transporter, BtuC-like A4G23_RS22140 6dadc0999caac420bf85e2de87c78338 348 SUPERFAMILY SSF81345 8 337 8.11E-80 T 10-11-2016 IPR029022 ABC transporter, BtuC-like A4G23_RS22140 6dadc0999caac420bf85e2de87c78338 348 Pfam PF01032 FecCD transport family 16 337 1.1E-90 T 10-11-2016 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 A4G23_RS02265 89e5b6a7f661dcf1faf0202859ed2b95 422 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 39 280 1.9E-39 T 10-11-2016 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 A4G23_RS02265 89e5b6a7f661dcf1faf0202859ed2b95 422 PRINTS PR01181 Diaminopimelate decarboxylase signature 157 166 3.0E-7 T 10-11-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4G23_RS02265 89e5b6a7f661dcf1faf0202859ed2b95 422 PRINTS PR01181 Diaminopimelate decarboxylase signature 69 86 3.0E-7 T 10-11-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4G23_RS02265 89e5b6a7f661dcf1faf0202859ed2b95 422 PRINTS PR01181 Diaminopimelate decarboxylase signature 298 316 3.0E-7 T 10-11-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4G23_RS02265 89e5b6a7f661dcf1faf0202859ed2b95 422 PRINTS PR01181 Diaminopimelate decarboxylase signature 385 407 3.0E-7 T 10-11-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4G23_RS02265 89e5b6a7f661dcf1faf0202859ed2b95 422 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 270 289 2.6E-7 T 10-11-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A4G23_RS02265 89e5b6a7f661dcf1faf0202859ed2b95 422 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 183 196 2.6E-7 T 10-11-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A4G23_RS02265 89e5b6a7f661dcf1faf0202859ed2b95 422 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 51 69 2.6E-7 T 10-11-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A4G23_RS02265 89e5b6a7f661dcf1faf0202859ed2b95 422 Gene3D G3DSA:2.40.37.10 263 418 1.1E-39 T 10-11-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A4G23_RS02265 89e5b6a7f661dcf1faf0202859ed2b95 422 SUPERFAMILY SSF51419 21 282 3.2E-65 T 10-11-2016 IPR029066 PLP-binding barrel A4G23_RS02265 89e5b6a7f661dcf1faf0202859ed2b95 422 Gene3D G3DSA:3.20.20.10 30 262 1.2E-61 T 10-11-2016 IPR029066 PLP-binding barrel A4G23_RS02265 89e5b6a7f661dcf1faf0202859ed2b95 422 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 218 235 - T 10-11-2016 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site A4G23_RS02265 89e5b6a7f661dcf1faf0202859ed2b95 422 SUPERFAMILY SSF50621 260 418 5.44E-41 T 10-11-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A4G23_RS02265 89e5b6a7f661dcf1faf0202859ed2b95 422 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 3 417 2.9E-91 T 10-11-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4G23_RS02265 89e5b6a7f661dcf1faf0202859ed2b95 422 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 288 395 2.1E-11 T 10-11-2016 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 A4G23_RS01990 1a220380ee68ed5485aa2916af846b06 174 SUPERFAMILY SSF55729 15 122 1.36E-6 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS01990 1a220380ee68ed5485aa2916af846b06 174 Gene3D G3DSA:3.40.630.30 11 137 6.0E-7 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS26395 01555e1f6766fc7419b3244ed84afb80 277 TIGRFAM TIGR00552 nadE: NAD+ synthetase 25 274 1.1E-61 T 10-11-2016 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 A4G23_RS26395 01555e1f6766fc7419b3244ed84afb80 277 Pfam PF02540 NAD synthase 29 273 7.8E-63 T 10-11-2016 IPR022310 NAD/GMP synthase A4G23_RS26395 01555e1f6766fc7419b3244ed84afb80 277 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 23 276 32.044 T 10-11-2016 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 A4G23_RS26395 01555e1f6766fc7419b3244ed84afb80 277 Gene3D G3DSA:3.40.50.620 10 274 2.6E-69 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS26395 01555e1f6766fc7419b3244ed84afb80 277 SUPERFAMILY SSF52402 9 275 4.45E-74 T 10-11-2016 A4G23_RS04320 1f4f9c5c9e01756ce6b41ec52f670649 103 Gene3D G3DSA:3.30.70.20 16 100 6.4E-28 T 10-11-2016 A4G23_RS04320 1f4f9c5c9e01756ce6b41ec52f670649 103 PRINTS PR00352 3Fe-4S ferredoxin signature 74 86 2.7E-6 T 10-11-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A4G23_RS04320 1f4f9c5c9e01756ce6b41ec52f670649 103 PRINTS PR00352 3Fe-4S ferredoxin signature 31 41 2.7E-6 T 10-11-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A4G23_RS04320 1f4f9c5c9e01756ce6b41ec52f670649 103 PRINTS PR00352 3Fe-4S ferredoxin signature 20 31 2.7E-6 T 10-11-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A4G23_RS04320 1f4f9c5c9e01756ce6b41ec52f670649 103 Pfam PF13459 4Fe-4S single cluster domain 18 88 2.5E-18 T 10-11-2016 A4G23_RS04320 1f4f9c5c9e01756ce6b41ec52f670649 103 SUPERFAMILY SSF54862 17 88 2.99E-9 T 10-11-2016 A4G23_RS10345 f6a22e2408f62c3b8b7bf9d6df680e53 431 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 308 3.7E-38 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS10345 f6a22e2408f62c3b8b7bf9d6df680e53 431 Gene3D G3DSA:3.50.50.60 85 241 1.2E-18 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS10345 f6a22e2408f62c3b8b7bf9d6df680e53 431 SUPERFAMILY SSF51905 235 319 7.6E-19 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS10345 f6a22e2408f62c3b8b7bf9d6df680e53 431 SUPERFAMILY SSF51905 6 147 7.6E-19 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS10345 f6a22e2408f62c3b8b7bf9d6df680e53 431 Gene3D G3DSA:3.50.50.60 242 321 7.5E-20 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS10345 f6a22e2408f62c3b8b7bf9d6df680e53 431 Gene3D G3DSA:3.50.50.60 5 84 7.5E-20 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS10345 f6a22e2408f62c3b8b7bf9d6df680e53 431 SUPERFAMILY SSF51905 75 95 1.07E-12 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS10345 f6a22e2408f62c3b8b7bf9d6df680e53 431 SUPERFAMILY SSF51905 134 240 1.07E-12 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS24165 434555a1a58af9e99f00199deb98d283 473 Pfam PF13450 NAD(P)-binding Rossmann-like domain 9 57 6.6E-10 T 10-11-2016 A4G23_RS24165 434555a1a58af9e99f00199deb98d283 473 Gene3D G3DSA:3.50.50.60 6 104 3.1E-17 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS24165 434555a1a58af9e99f00199deb98d283 473 SUPERFAMILY SSF51905 424 468 1.42E-29 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS24165 434555a1a58af9e99f00199deb98d283 473 SUPERFAMILY SSF51905 5 302 1.42E-29 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS24165 434555a1a58af9e99f00199deb98d283 473 Gene3D G3DSA:3.50.50.60 207 286 5.6E-9 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS24165 434555a1a58af9e99f00199deb98d283 473 Gene3D G3DSA:3.50.50.60 435 470 5.6E-9 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS12145 04bf18cab0509d17d685bd46114046de 187 SMART SM00530 11 66 5.8E-18 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS12145 04bf18cab0509d17d685bd46114046de 187 SUPERFAMILY SSF51182 66 172 1.35E-22 T 10-11-2016 IPR011051 RmlC-like cupin domain A4G23_RS12145 04bf18cab0509d17d685bd46114046de 187 Pfam PF07883 Cupin domain 104 172 1.8E-17 T 10-11-2016 IPR013096 Cupin 2, conserved barrel A4G23_RS12145 04bf18cab0509d17d685bd46114046de 187 SUPERFAMILY SSF47413 7 72 4.02E-18 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS12145 04bf18cab0509d17d685bd46114046de 187 Gene3D G3DSA:2.60.120.10 84 173 1.9E-16 T 10-11-2016 IPR014710 RmlC-like jelly roll fold A4G23_RS12145 04bf18cab0509d17d685bd46114046de 187 Pfam PF13560 Helix-turn-helix domain 8 66 1.4E-15 T 10-11-2016 A4G23_RS12145 04bf18cab0509d17d685bd46114046de 187 Gene3D G3DSA:1.10.260.40 7 78 2.2E-21 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS04715 705d6b13e93a029aad4a3fb2f1af7624 363 Gene3D G3DSA:3.40.50.300 180 305 7.2E-14 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS04715 705d6b13e93a029aad4a3fb2f1af7624 363 SMART SM00382 178 315 1.7E-5 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS04715 705d6b13e93a029aad4a3fb2f1af7624 363 SUPERFAMILY SSF52540 179 314 3.52E-18 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS04715 705d6b13e93a029aad4a3fb2f1af7624 363 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 182 311 9.8E-11 T 10-11-2016 IPR003959 ATPase, AAA-type, core GO:0005524 A4G23_RS05610 c78778d07a2e1528d9851aa0a859488f 307 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 73 95 - T 10-11-2016 IPR030470 UbiA prenyltransferase conserved site A4G23_RS05610 c78778d07a2e1528d9851aa0a859488f 307 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 18 305 19.336 T 10-11-2016 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 A4G23_RS05610 c78778d07a2e1528d9851aa0a859488f 307 Pfam PF01040 UbiA prenyltransferase family 34 290 3.4E-67 T 10-11-2016 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 A4G23_RS05610 c78778d07a2e1528d9851aa0a859488f 307 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 20 303 2.3E-96 T 10-11-2016 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 A4G23_RS18430 fd641d7b5263bd8cd64de3c7f0aadb62 367 SMART SM00382 58 250 7.0E-16 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS18430 fd641d7b5263bd8cd64de3c7f0aadb62 367 SUPERFAMILY SSF52540 21 271 7.37E-72 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS18430 fd641d7b5263bd8cd64de3c7f0aadb62 367 ProSitePatterns PS00211 ABC transporters family signature. 173 187 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS18430 fd641d7b5263bd8cd64de3c7f0aadb62 367 Gene3D G3DSA:3.40.50.300 20 274 3.4E-79 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS18430 fd641d7b5263bd8cd64de3c7f0aadb62 367 Pfam PF00005 ABC transporter 50 200 2.5E-31 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS18430 fd641d7b5263bd8cd64de3c7f0aadb62 367 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 252 318 3.6E-17 T 10-11-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A4G23_RS18430 fd641d7b5263bd8cd64de3c7f0aadb62 367 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 250 341 6.3E-27 T 10-11-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A4G23_RS08175 17400982c3388a7b1171409c2a3031b9 368 SUPERFAMILY SSF53756 2 361 1.49E-89 T 10-11-2016 A4G23_RS08175 17400982c3388a7b1171409c2a3031b9 368 Gene3D G3DSA:3.40.50.2000 206 359 1.6E-32 T 10-11-2016 A4G23_RS08175 17400982c3388a7b1171409c2a3031b9 368 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 1 358 1.6E-73 T 10-11-2016 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 KEGG: 00520+5.1.3.14|MetaCyc: PWY-7335 A4G23_RS08175 17400982c3388a7b1171409c2a3031b9 368 Gene3D G3DSA:3.40.50.2000 2 205 7.9E-72 T 10-11-2016 A4G23_RS08175 17400982c3388a7b1171409c2a3031b9 368 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 25 358 7.3E-90 T 10-11-2016 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A4G23_RS24460 5961222f4a1d5fabc766dc529bb07e4d 324 SUPERFAMILY SSF56281 72 293 1.44E-37 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS24460 5961222f4a1d5fabc766dc529bb07e4d 324 Gene3D G3DSA:3.60.15.10 64 319 1.1E-75 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS24460 5961222f4a1d5fabc766dc529bb07e4d 324 Pfam PF12706 Beta-lactamase superfamily domain 91 281 3.8E-45 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS24325 673671777906315f1f3a62429dfffa09 148 Gene3D G3DSA:3.30.530.20 3 146 4.3E-7 T 10-11-2016 IPR023393 START-like domain A4G23_RS24325 673671777906315f1f3a62429dfffa09 148 PIRSF PIRSF017371 1 147 2.7E-70 T 10-11-2016 IPR014488 Uncharacterised conserved protein UCP017371 A4G23_RS24325 673671777906315f1f3a62429dfffa09 148 SUPERFAMILY SSF55961 5 137 1.15E-18 T 10-11-2016 A4G23_RS24325 673671777906315f1f3a62429dfffa09 148 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 4 146 5.2E-24 T 10-11-2016 IPR019587 Polyketide cyclase/dehydrase A4G23_RS05490 d7a489f37bf04d182eb1218480e5884d 406 Pfam PF02342 TerD domain 224 391 3.9E-39 T 10-11-2016 IPR003325 TerD domain GO:0006950 A4G23_RS05490 d7a489f37bf04d182eb1218480e5884d 406 Pfam PF02342 TerD domain 20 158 8.6E-29 T 10-11-2016 IPR003325 TerD domain GO:0006950 A4G23_RS05490 d7a489f37bf04d182eb1218480e5884d 406 Gene3D G3DSA:2.60.60.30 242 395 6.1E-49 T 10-11-2016 A4G23_RS05490 d7a489f37bf04d182eb1218480e5884d 406 Gene3D G3DSA:2.60.60.30 20 156 2.1E-27 T 10-11-2016 A4G23_RS21065 79fbdbe612d929a8b39086c14861bb2b 1841 SUPERFAMILY SSF58104 582 673 4.18E-6 T 10-11-2016 A4G23_RS21065 79fbdbe612d929a8b39086c14861bb2b 1841 SUPERFAMILY SSF55874 1385 1577 2.1E-44 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS21065 79fbdbe612d929a8b39086c14861bb2b 1841 SMART SM00387 1443 1576 1.1E-36 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS21065 79fbdbe612d929a8b39086c14861bb2b 1841 Pfam PF13185 GAF domain 1097 1241 7.9E-16 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS21065 79fbdbe612d929a8b39086c14861bb2b 1841 SUPERFAMILY SSF58104 674 947 1.15E-17 T 10-11-2016 A4G23_RS21065 79fbdbe612d929a8b39086c14861bb2b 1841 SUPERFAMILY SSF58104 306 436 2.59E-10 T 10-11-2016 A4G23_RS21065 79fbdbe612d929a8b39086c14861bb2b 1841 SUPERFAMILY SSF58104 131 301 6.02E-8 T 10-11-2016 A4G23_RS21065 79fbdbe612d929a8b39086c14861bb2b 1841 Gene3D G3DSA:3.40.50.2300 1716 1839 2.8E-39 T 10-11-2016 A4G23_RS21065 79fbdbe612d929a8b39086c14861bb2b 1841 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1501 1515 1.7E-16 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS21065 79fbdbe612d929a8b39086c14861bb2b 1841 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1519 1529 1.7E-16 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS21065 79fbdbe612d929a8b39086c14861bb2b 1841 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1560 1573 1.7E-16 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS21065 79fbdbe612d929a8b39086c14861bb2b 1841 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1536 1554 1.7E-16 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS21065 79fbdbe612d929a8b39086c14861bb2b 1841 Pfam PF00512 His Kinase A (phospho-acceptor) domain 1329 1396 4.3E-18 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS21065 79fbdbe612d929a8b39086c14861bb2b 1841 Pfam PF00072 Response regulator receiver domain 1722 1833 4.3E-26 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS21065 79fbdbe612d929a8b39086c14861bb2b 1841 Gene3D G3DSA:3.30.565.10 1382 1578 4.7E-44 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS21065 79fbdbe612d929a8b39086c14861bb2b 1841 SUPERFAMILY SSF58104 398 578 2.3E-10 T 10-11-2016 A4G23_RS21065 79fbdbe612d929a8b39086c14861bb2b 1841 SMART SM00304 746 798 1.0E-9 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS21065 79fbdbe612d929a8b39086c14861bb2b 1841 SMART SM00304 930 982 6.0E-11 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS21065 79fbdbe612d929a8b39086c14861bb2b 1841 SMART SM00304 194 246 3.2E-5 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS21065 79fbdbe612d929a8b39086c14861bb2b 1841 SMART SM00304 3 52 5.8 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS21065 79fbdbe612d929a8b39086c14861bb2b 1841 SMART SM00304 562 614 3.5E-11 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS21065 79fbdbe612d929a8b39086c14861bb2b 1841 SMART SM00304 654 706 5.3E-11 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS21065 79fbdbe612d929a8b39086c14861bb2b 1841 SMART SM00304 92 154 4.3E-4 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS21065 79fbdbe612d929a8b39086c14861bb2b 1841 SMART SM00304 838 890 1.9E-9 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS21065 79fbdbe612d929a8b39086c14861bb2b 1841 SMART SM00304 286 338 2.5E-10 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS21065 79fbdbe612d929a8b39086c14861bb2b 1841 SMART SM00304 470 522 4.8E-9 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS21065 79fbdbe612d929a8b39086c14861bb2b 1841 SMART SM00304 1022 1074 1.6E-8 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS21065 79fbdbe612d929a8b39086c14861bb2b 1841 SMART SM00304 378 430 6.1E-8 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS21065 79fbdbe612d929a8b39086c14861bb2b 1841 SUPERFAMILY SSF58104 950 1072 4.45E-9 T 10-11-2016 A4G23_RS21065 79fbdbe612d929a8b39086c14861bb2b 1841 SUPERFAMILY SSF52172 1714 1839 8.54E-37 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS21065 79fbdbe612d929a8b39086c14861bb2b 1841 Pfam PF00672 HAMP domain 743 794 2.2E-6 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS21065 79fbdbe612d929a8b39086c14861bb2b 1841 Pfam PF00672 HAMP domain 559 610 1.2E-6 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS21065 79fbdbe612d929a8b39086c14861bb2b 1841 Pfam PF00672 HAMP domain 929 978 8.7E-7 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS21065 79fbdbe612d929a8b39086c14861bb2b 1841 Pfam PF00672 HAMP domain 652 702 2.0E-6 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS21065 79fbdbe612d929a8b39086c14861bb2b 1841 Pfam PF00672 HAMP domain 835 885 1.8E-6 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS21065 79fbdbe612d929a8b39086c14861bb2b 1841 Pfam PF00672 HAMP domain 284 334 1.0E-7 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS21065 79fbdbe612d929a8b39086c14861bb2b 1841 SUPERFAMILY SSF47384 1314 1398 4.9E-21 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS21065 79fbdbe612d929a8b39086c14861bb2b 1841 SMART SM00448 1720 1834 2.5E-37 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS21065 79fbdbe612d929a8b39086c14861bb2b 1841 SMART SM00065 1098 1253 6.8E-5 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS21065 79fbdbe612d929a8b39086c14861bb2b 1841 SMART SM00388 1328 1396 1.2E-23 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS21065 79fbdbe612d929a8b39086c14861bb2b 1841 SUPERFAMILY SSF55781 1061 1243 5.49E-25 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS21065 79fbdbe612d929a8b39086c14861bb2b 1841 Gene3D G3DSA:1.10.287.130 1319 1381 3.7E-16 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS21065 79fbdbe612d929a8b39086c14861bb2b 1841 Gene3D G3DSA:3.30.450.40 1078 1243 2.3E-20 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS21065 79fbdbe612d929a8b39086c14861bb2b 1841 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1443 1574 7.9E-27 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS14765 bfae12eeb60623692c4dab911161c043 180 Gene3D G3DSA:1.10.1220.10 119 158 5.6E-9 T 10-11-2016 IPR013321 Arc-type ribbon-helix-helix GO:0006355 A4G23_RS14765 bfae12eeb60623692c4dab911161c043 180 Pfam PF05534 HicB family 122 151 1.8E-4 T 10-11-2016 IPR008651 Uncharacterised protein family HicB A4G23_RS14765 bfae12eeb60623692c4dab911161c043 180 SUPERFAMILY SSF47598 117 169 4.45E-11 T 10-11-2016 IPR010985 Ribbon-helix-helix GO:0006355 A4G23_RS12985 4a253d66b400c6e6ec3b9e717ead244e 490 SUPERFAMILY SSF52540 5 213 2.66E-15 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS12985 4a253d66b400c6e6ec3b9e717ead244e 490 Gene3D G3DSA:3.40.50.300 4 176 1.4E-14 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS04475 aede13f5d1e26a1a9362ce432b5a76a8 389 Gene3D G3DSA:3.20.20.150 5 387 1.4E-138 T 10-11-2016 IPR013022 Xylose isomerase-like, TIM barrel domain A4G23_RS04475 aede13f5d1e26a1a9362ce432b5a76a8 389 Hamap MF_00455 Xylose isomerase [xylA]. 3 385 36.354 T 10-11-2016 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 A4G23_RS04475 aede13f5d1e26a1a9362ce432b5a76a8 389 SUPERFAMILY SSF51658 5 387 2.49E-113 T 10-11-2016 IPR013022 Xylose isomerase-like, TIM barrel domain A4G23_RS04475 aede13f5d1e26a1a9362ce432b5a76a8 389 TIGRFAM TIGR02631 xylA_Arthro: xylose isomerase 5 386 5.6E-212 T 10-11-2016 IPR013453 Xylose isomerase, actinobacteria GO:0009045|GO:0042732 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 A4G23_RS04475 aede13f5d1e26a1a9362ce432b5a76a8 389 Pfam PF01261 Xylose isomerase-like TIM barrel 43 267 3.5E-26 T 10-11-2016 IPR013022 Xylose isomerase-like, TIM barrel domain A4G23_RS04475 aede13f5d1e26a1a9362ce432b5a76a8 389 PRINTS PR00688 Xylose isomerase signature 222 249 7.4E-73 T 10-11-2016 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 A4G23_RS04475 aede13f5d1e26a1a9362ce432b5a76a8 389 PRINTS PR00688 Xylose isomerase signature 131 152 7.4E-73 T 10-11-2016 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 A4G23_RS04475 aede13f5d1e26a1a9362ce432b5a76a8 389 PRINTS PR00688 Xylose isomerase signature 47 69 7.4E-73 T 10-11-2016 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 A4G23_RS04475 aede13f5d1e26a1a9362ce432b5a76a8 389 PRINTS PR00688 Xylose isomerase signature 250 261 7.4E-73 T 10-11-2016 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 A4G23_RS04475 aede13f5d1e26a1a9362ce432b5a76a8 389 PRINTS PR00688 Xylose isomerase signature 107 126 7.4E-73 T 10-11-2016 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 A4G23_RS04475 aede13f5d1e26a1a9362ce432b5a76a8 389 PRINTS PR00688 Xylose isomerase signature 158 177 7.4E-73 T 10-11-2016 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 A4G23_RS04475 aede13f5d1e26a1a9362ce432b5a76a8 389 PRINTS PR00688 Xylose isomerase signature 180 204 7.4E-73 T 10-11-2016 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 A4G23_RS04475 aede13f5d1e26a1a9362ce432b5a76a8 389 PRINTS PR00688 Xylose isomerase signature 283 294 7.4E-73 T 10-11-2016 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 A4G23_RS04475 aede13f5d1e26a1a9362ce432b5a76a8 389 PRINTS PR00688 Xylose isomerase signature 84 104 7.4E-73 T 10-11-2016 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 A4G23_RS17670 7d89f3d99454449077a315a9faec0e44 231 SMART SM00862 151 227 2.4E-23 T 10-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4G23_RS17670 7d89f3d99454449077a315a9faec0e44 231 Pfam PF00072 Response regulator receiver domain 11 118 8.9E-29 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS17670 7d89f3d99454449077a315a9faec0e44 231 SMART SM00448 8 118 2.2E-40 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS17670 7d89f3d99454449077a315a9faec0e44 231 SUPERFAMILY SSF52172 10 179 1.07E-40 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS17670 7d89f3d99454449077a315a9faec0e44 231 Gene3D G3DSA:3.40.50.2300 10 129 9.1E-41 T 10-11-2016 A4G23_RS17670 7d89f3d99454449077a315a9faec0e44 231 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 227 8.3E-25 T 10-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4G23_RS17670 7d89f3d99454449077a315a9faec0e44 231 Gene3D G3DSA:1.10.10.10 130 229 6.7E-33 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS19530 47cffaf3e809e24912e30d634fd357e9 406 PIRSF PIRSF000412 1 400 5.1E-139 T 10-11-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A4G23_RS19530 47cffaf3e809e24912e30d634fd357e9 406 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 1 404 44.011 T 10-11-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A4G23_RS19530 47cffaf3e809e24912e30d634fd357e9 406 Gene3D G3DSA:3.90.1150.10 277 403 1.0E-28 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS19530 47cffaf3e809e24912e30d634fd357e9 406 SUPERFAMILY SSF53383 2 403 1.02E-141 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS19530 47cffaf3e809e24912e30d634fd357e9 406 Pfam PF00464 Serine hydroxymethyltransferase 2 371 3.2E-127 T 10-11-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A4G23_RS19530 47cffaf3e809e24912e30d634fd357e9 406 Gene3D G3DSA:3.40.640.10 30 276 3.5E-92 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS24525 593a02d508ee5cb68f881b091f1ced4d 332 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 261 303 - T 10-11-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A4G23_RS24525 593a02d508ee5cb68f881b091f1ced4d 332 SUPERFAMILY SSF46689 260 310 1.21E-11 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS24525 593a02d508ee5cb68f881b091f1ced4d 332 Gene3D G3DSA:1.10.10.60 207 261 3.0E-12 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS24525 593a02d508ee5cb68f881b091f1ced4d 332 Gene3D G3DSA:1.10.10.60 262 309 4.7E-14 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS24525 593a02d508ee5cb68f881b091f1ced4d 332 Pfam PF12833 Helix-turn-helix domain 230 308 5.0E-20 T 10-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4G23_RS24525 593a02d508ee5cb68f881b091f1ced4d 332 SUPERFAMILY SSF46689 207 257 2.33E-8 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS24525 593a02d508ee5cb68f881b091f1ced4d 332 SMART SM00342 224 307 1.9E-29 T 10-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4G23_RS24525 593a02d508ee5cb68f881b091f1ced4d 332 Pfam PF12852 Cupin 2 192 1.7E-49 T 10-11-2016 IPR032783 AraC-type transcription regulator, ligand-binding domain A4G23_RS13385 f5f51f5ea3094f81b002ebf7b4c7e763 175 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 7 171 3.8E-46 T 10-11-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 A4G23_RS13385 f5f51f5ea3094f81b002ebf7b4c7e763 175 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 56 73 - T 10-11-2016 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 A4G23_RS13385 f5f51f5ea3094f81b002ebf7b4c7e763 175 SUPERFAMILY SSF50891 6 171 1.9E-60 T 10-11-2016 IPR029000 Cyclophilin-like domain A4G23_RS13385 f5f51f5ea3094f81b002ebf7b4c7e763 175 PIRSF PIRSF001467 2 175 2.2E-55 T 10-11-2016 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755|GO:0006457 A4G23_RS13385 f5f51f5ea3094f81b002ebf7b4c7e763 175 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 116 128 1.0E-27 T 10-11-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 A4G23_RS13385 f5f51f5ea3094f81b002ebf7b4c7e763 175 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 61 73 1.0E-27 T 10-11-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 A4G23_RS13385 f5f51f5ea3094f81b002ebf7b4c7e763 175 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 20 35 1.0E-27 T 10-11-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 A4G23_RS13385 f5f51f5ea3094f81b002ebf7b4c7e763 175 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 129 144 1.0E-27 T 10-11-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 A4G23_RS13385 f5f51f5ea3094f81b002ebf7b4c7e763 175 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 101 116 1.0E-27 T 10-11-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 A4G23_RS13385 f5f51f5ea3094f81b002ebf7b4c7e763 175 Gene3D G3DSA:2.40.100.10 4 172 9.0E-62 T 10-11-2016 IPR029000 Cyclophilin-like domain A4G23_RS14315 13e4ad3dd625394cca565add69c88a5d 369 SUPERFAMILY SSF54631 288 365 4.11E-13 T 10-11-2016 A4G23_RS14315 13e4ad3dd625394cca565add69c88a5d 369 SUPERFAMILY SSF54631 208 260 4.11E-13 T 10-11-2016 A4G23_RS14315 13e4ad3dd625394cca565add69c88a5d 369 Pfam PF01595 Domain of unknown function DUF21 9 200 5.6E-41 T 10-11-2016 IPR002550 Domain of unknown function DUF21 A4G23_RS14315 13e4ad3dd625394cca565add69c88a5d 369 Gene3D G3DSA:3.20.20.70 184 364 8.3E-9 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS14315 13e4ad3dd625394cca565add69c88a5d 369 Pfam PF00571 CBS domain 315 364 1.6E-6 T 10-11-2016 IPR000644 CBS domain A4G23_RS23930 42c7b5e49a097fb62df1d39dda8200cf 116 Pfam PF03061 Thioesterase superfamily 49 115 1.3E-11 T 10-11-2016 IPR006683 Thioesterase domain Reactome: R-HSA-75105 A4G23_RS23930 42c7b5e49a097fb62df1d39dda8200cf 116 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 21 112 7.2E-17 T 10-11-2016 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-75105 A4G23_RS23930 42c7b5e49a097fb62df1d39dda8200cf 116 SUPERFAMILY SSF54637 8 115 5.4E-27 T 10-11-2016 IPR029069 HotDog domain A4G23_RS23930 42c7b5e49a097fb62df1d39dda8200cf 116 Gene3D G3DSA:3.10.129.10 10 115 4.9E-31 T 10-11-2016 IPR029069 HotDog domain A4G23_RS21310 1a96714a076dc76a5610af7f9873b6f6 230 SUPERFAMILY SSF48498 86 204 2.36E-22 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS21310 1a96714a076dc76a5610af7f9873b6f6 230 Pfam PF00440 Bacterial regulatory proteins, tetR family 36 72 2.4E-7 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS21310 1a96714a076dc76a5610af7f9873b6f6 230 SUPERFAMILY SSF46689 19 82 6.48E-12 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS21310 1a96714a076dc76a5610af7f9873b6f6 230 Gene3D G3DSA:1.10.357.10 68 205 1.2E-36 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS21310 1a96714a076dc76a5610af7f9873b6f6 230 Pfam PF16859 Bacterial transcriptional repressor C-terminal 85 196 1.0E-26 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS21310 1a96714a076dc76a5610af7f9873b6f6 230 Gene3D G3DSA:1.10.10.60 18 65 4.9E-19 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS02625 ab68f10e6d9e0ca0823576f34904d1f0 278 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 12 183 4.3E-21 T 10-11-2016 IPR013830 SGNH hydrolase-type esterase domain A4G23_RS02625 ab68f10e6d9e0ca0823576f34904d1f0 278 SUPERFAMILY SSF52266 9 192 1.05E-34 T 10-11-2016 IPR013830 SGNH hydrolase-type esterase domain A4G23_RS02625 ab68f10e6d9e0ca0823576f34904d1f0 278 Gene3D G3DSA:3.40.50.1110 10 193 3.2E-33 T 10-11-2016 IPR013830 SGNH hydrolase-type esterase domain A4G23_RS26150 b726e610049a6381dfbb0300dfc9ea40 306 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 223 299 3.0E-16 T 10-11-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A4G23_RS26150 b726e610049a6381dfbb0300dfc9ea40 306 Pfam PF00005 ABC transporter 12 174 7.7E-20 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS26150 b726e610049a6381dfbb0300dfc9ea40 306 Gene3D G3DSA:3.40.50.300 6 253 1.1E-56 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS26150 b726e610049a6381dfbb0300dfc9ea40 306 SMART SM00382 19 223 5.0E-15 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS26150 b726e610049a6381dfbb0300dfc9ea40 306 SUPERFAMILY SSF52540 6 226 5.55E-49 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS26150 b726e610049a6381dfbb0300dfc9ea40 306 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 225 286 3.3E-12 T 10-11-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A4G23_RS06600 4f765e55a7632d3fdbf597da1a744d6f 118 Pfam PF01521 Iron-sulphur cluster biosynthesis 14 115 2.2E-20 T 10-11-2016 IPR000361 FeS cluster biogenesis A4G23_RS06600 4f765e55a7632d3fdbf597da1a744d6f 118 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 14 118 9.9E-37 T 10-11-2016 IPR016092 FeS cluster insertion protein GO:0005198|GO:0016226|GO:0051536 A4G23_RS06600 4f765e55a7632d3fdbf597da1a744d6f 118 SUPERFAMILY SSF89360 14 108 2.35E-28 T 10-11-2016 IPR000361 FeS cluster biogenesis A4G23_RS06600 4f765e55a7632d3fdbf597da1a744d6f 118 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 100 117 - T 10-11-2016 IPR017870 FeS cluster insertion, C-terminal, conserved site A4G23_RS06600 4f765e55a7632d3fdbf597da1a744d6f 118 Gene3D G3DSA:2.60.300.12 14 108 2.2E-29 T 10-11-2016 IPR000361 FeS cluster biogenesis A4G23_RS00300 632fc2e77c213bd664c8943adfab8b2f 387 Pfam PF05922 Peptidase inhibitor I9 66 110 7.9E-8 T 10-11-2016 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 A4G23_RS00300 632fc2e77c213bd664c8943adfab8b2f 387 Gene3D G3DSA:3.40.50.200 117 367 7.9E-79 T 10-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4G23_RS00300 632fc2e77c213bd664c8943adfab8b2f 387 PRINTS PR00723 Subtilisin serine protease family (S8) signature 178 191 8.1E-21 T 10-11-2016 IPR015500 Peptidase S8, subtilisin-related A4G23_RS00300 632fc2e77c213bd664c8943adfab8b2f 387 PRINTS PR00723 Subtilisin serine protease family (S8) signature 142 161 8.1E-21 T 10-11-2016 IPR015500 Peptidase S8, subtilisin-related A4G23_RS00300 632fc2e77c213bd664c8943adfab8b2f 387 PRINTS PR00723 Subtilisin serine protease family (S8) signature 329 345 8.1E-21 T 10-11-2016 IPR015500 Peptidase S8, subtilisin-related A4G23_RS00300 632fc2e77c213bd664c8943adfab8b2f 387 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 182 192 - T 10-11-2016 IPR022398 Peptidase S8, subtilisin, His-active site A4G23_RS00300 632fc2e77c213bd664c8943adfab8b2f 387 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 330 340 - T 10-11-2016 IPR023828 Peptidase S8, subtilisin, Ser-active site A4G23_RS00300 632fc2e77c213bd664c8943adfab8b2f 387 SUPERFAMILY SSF54897 47 111 1.19E-11 T 10-11-2016 IPR009020 Proteinase propeptide inhibitor A4G23_RS00300 632fc2e77c213bd664c8943adfab8b2f 387 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 147 158 - T 10-11-2016 IPR023827 Peptidase S8, subtilisin, Asp-active site A4G23_RS00300 632fc2e77c213bd664c8943adfab8b2f 387 Pfam PF00082 Subtilase family 143 366 4.8E-29 T 10-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4G23_RS00300 632fc2e77c213bd664c8943adfab8b2f 387 SUPERFAMILY SSF52743 116 367 2.75E-72 T 10-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4G23_RS00300 632fc2e77c213bd664c8943adfab8b2f 387 Gene3D G3DSA:3.30.70.80 43 116 5.2E-17 T 10-11-2016 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 A4G23_RS01325 7530a325305bb32dd6c14019033269c6 407 SUPERFAMILY SSF51445 5 380 1.86E-80 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS01325 7530a325305bb32dd6c14019033269c6 407 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 17 350 4.8E-58 T 10-11-2016 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 A4G23_RS01325 7530a325305bb32dd6c14019033269c6 407 Gene3D G3DSA:3.20.20.80 2 377 3.3E-114 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS01325 7530a325305bb32dd6c14019033269c6 407 ProSitePatterns PS00659 Glycosyl hydrolases family 5 signature. 165 174 - T 10-11-2016 IPR018087 Glycoside hydrolase, family 5, conserved site GO:0004553|GO:0005975 A4G23_RS22045 9e8bfecae554de0070a28ff6d545bf25 559 Gene3D G3DSA:3.30.750.24 443 544 9.9E-15 T 10-11-2016 IPR002645 STAS domain A4G23_RS22045 9e8bfecae554de0070a28ff6d545bf25 559 Pfam PF01740 STAS domain 443 530 6.7E-13 T 10-11-2016 IPR002645 STAS domain A4G23_RS22045 9e8bfecae554de0070a28ff6d545bf25 559 SUPERFAMILY SSF52091 441 544 8.44E-16 T 10-11-2016 IPR002645 STAS domain A4G23_RS22045 9e8bfecae554de0070a28ff6d545bf25 559 Pfam PF00916 Sulfate permease family 27 385 5.6E-67 T 10-11-2016 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 A4G23_RS20965 27f64385dd1d8c140b302009e3a69e69 419 SUPERFAMILY SSF52743 43 322 3.67E-65 T 10-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4G23_RS20965 27f64385dd1d8c140b302009e3a69e69 419 Pfam PF00082 Subtilase family 60 313 1.1E-39 T 10-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4G23_RS20965 27f64385dd1d8c140b302009e3a69e69 419 Gene3D G3DSA:3.40.50.200 36 323 2.2E-67 T 10-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4G23_RS20965 27f64385dd1d8c140b302009e3a69e69 419 PRINTS PR00723 Subtilisin serine protease family (S8) signature 259 275 2.3E-11 T 10-11-2016 IPR015500 Peptidase S8, subtilisin-related A4G23_RS20965 27f64385dd1d8c140b302009e3a69e69 419 PRINTS PR00723 Subtilisin serine protease family (S8) signature 98 111 2.3E-11 T 10-11-2016 IPR015500 Peptidase S8, subtilisin-related A4G23_RS20965 27f64385dd1d8c140b302009e3a69e69 419 PRINTS PR00723 Subtilisin serine protease family (S8) signature 60 79 2.3E-11 T 10-11-2016 IPR015500 Peptidase S8, subtilisin-related A4G23_RS03720 77bdc373a2169e4735e80a47cb2affb9 364 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 272 345 1.3E-29 T 10-11-2016 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 A4G23_RS03720 77bdc373a2169e4735e80a47cb2affb9 364 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 43 346 6.0E-135 T 10-11-2016 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 A4G23_RS03720 77bdc373a2169e4735e80a47cb2affb9 364 SMART SM00382 70 201 9.6E-10 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS03720 77bdc373a2169e4735e80a47cb2affb9 364 Gene3D G3DSA:3.40.50.300 39 83 2.3E-9 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS03720 77bdc373a2169e4735e80a47cb2affb9 364 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 364 159.465 T 10-11-2016 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 A4G23_RS03720 77bdc373a2169e4735e80a47cb2affb9 364 SUPERFAMILY SSF52540 39 270 1.2E-50 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS03720 77bdc373a2169e4735e80a47cb2affb9 364 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 271 346 6.0E-24 T 10-11-2016 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 A4G23_RS03720 77bdc373a2169e4735e80a47cb2affb9 364 Gene3D G3DSA:1.10.8.60 211 274 8.7E-32 T 10-11-2016 A4G23_RS03720 77bdc373a2169e4735e80a47cb2affb9 364 Gene3D G3DSA:3.40.50.300 84 210 1.8E-22 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS03720 77bdc373a2169e4735e80a47cb2affb9 364 Gene3D G3DSA:1.10.10.10 276 346 2.6E-31 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS03720 77bdc373a2169e4735e80a47cb2affb9 364 SUPERFAMILY SSF46785 276 349 4.53E-22 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS03720 77bdc373a2169e4735e80a47cb2affb9 364 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 24 254 2.5E-109 T 10-11-2016 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 A4G23_RS22605 b53c6115233358c4af43f43cb118cef0 382 Gene3D G3DSA:2.40.10.10 166 242 3.0E-7 T 10-11-2016 A4G23_RS22605 b53c6115233358c4af43f43cb118cef0 382 Pfam PF13365 Trypsin-like peptidase domain 168 324 2.2E-16 T 10-11-2016 A4G23_RS22605 b53c6115233358c4af43f43cb118cef0 382 SUPERFAMILY SSF50494 144 337 3.03E-22 T 10-11-2016 IPR009003 Peptidase S1, PA clan A4G23_RS22605 b53c6115233358c4af43f43cb118cef0 382 Gene3D G3DSA:2.40.10.10 243 328 6.0E-12 T 10-11-2016 A4G23_RS08525 894818dcb614f54892355eef4f072d03 344 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 91 228 3.2E-25 T 10-11-2016 A4G23_RS08525 894818dcb614f54892355eef4f072d03 344 Gene3D G3DSA:3.40.50.150 34 264 3.5E-63 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS08525 894818dcb614f54892355eef4f072d03 344 SUPERFAMILY SSF53335 28 225 4.09E-27 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS17115 bc54a18745db6f4983f28eb98e780dba 137 Gene3D G3DSA:3.40.50.280 6 132 2.7E-55 T 10-11-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A4G23_RS17115 bc54a18745db6f4983f28eb98e780dba 137 Pfam PF02310 B12 binding domain 7 120 1.2E-23 T 10-11-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A4G23_RS17115 bc54a18745db6f4983f28eb98e780dba 137 SUPERFAMILY SSF52242 5 132 1.57E-49 T 10-11-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A4G23_RS17115 bc54a18745db6f4983f28eb98e780dba 137 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 7 133 5.0E-49 T 10-11-2016 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A4G23_RS06430 b47efaa9a494ed0d5c24044a33e260d1 289 Gene3D G3DSA:3.40.1130.10 13 203 3.4E-30 T 10-11-2016 A4G23_RS06430 b47efaa9a494ed0d5c24044a33e260d1 289 SUPERFAMILY SSF69593 11 216 3.01E-48 T 10-11-2016 A4G23_RS06430 b47efaa9a494ed0d5c24044a33e260d1 289 SMART SM00563 29 150 1.0E-33 T 10-11-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 A4G23_RS06430 b47efaa9a494ed0d5c24044a33e260d1 289 Pfam PF01553 Acyltransferase 17 147 4.1E-21 T 10-11-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 A4G23_RS22975 46f1828be94f5484d89102ead049b596 237 Gene3D G3DSA:3.30.70.1030 23 138 1.8E-27 T 10-11-2016 A4G23_RS22975 46f1828be94f5484d89102ead049b596 237 Pfam PF06778 Chlorite dismutase 42 226 4.8E-73 T 10-11-2016 IPR010644 Putative heme-dependent peroxidase/Chlorite dismutase A4G23_RS22975 46f1828be94f5484d89102ead049b596 237 SUPERFAMILY SSF54909 17 236 2.68E-75 T 10-11-2016 IPR011008 Dimeric alpha-beta barrel A4G23_RS22975 46f1828be94f5484d89102ead049b596 237 Gene3D G3DSA:3.30.70.1100 139 235 3.9E-40 T 10-11-2016 A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 SUPERFAMILY SSF52777 2099 2293 1.33E-42 T 10-11-2016 A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4565 4580 - T 10-11-2016 IPR006162 Phosphopantetheine attachment site A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 Gene3D G3DSA:2.30.38.10 311 390 1.0E-25 T 10-11-2016 A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 Gene3D G3DSA:2.30.38.10 1366 1443 3.3E-27 T 10-11-2016 A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 Gene3D G3DSA:2.30.38.10 4344 4420 3.4E-28 T 10-11-2016 A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 Gene3D G3DSA:2.30.38.10 2853 2931 3.7E-24 T 10-11-2016 A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 ProSitePatterns PS00455 Putative AMP-binding domain signature. 154 165 - T 10-11-2016 IPR020845 AMP-binding, conserved site A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 1947 2093 1.3E-39 T 10-11-2016 IPR010060 Non-ribosomal peptide synthase A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 3429 3576 3.1E-38 T 10-11-2016 IPR010060 Non-ribosomal peptide synthase A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 SUPERFAMILY SSF56801 7 524 3.14E-153 T 10-11-2016 A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 Gene3D G3DSA:1.10.1200.10 4545 4609 1.4E-25 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 Gene3D G3DSA:1.10.1200.10 3055 3115 5.5E-26 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 Gene3D G3DSA:1.10.1200.10 516 574 1.4E-25 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 Gene3D G3DSA:1.10.1200.10 1571 1630 5.0E-25 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 SUPERFAMILY SSF56801 2547 3063 1.03E-156 T 10-11-2016 A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 SUPERFAMILY SSF47336 503 574 6.02E-19 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2576 2965 8.3E-130 T 10-11-2016 IPR010071 Amino acid adenylation domain A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 38 425 3.0E-129 T 10-11-2016 IPR010071 Amino acid adenylation domain A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 4058 4454 1.5E-128 T 10-11-2016 IPR010071 Amino acid adenylation domain A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1077 1477 2.2E-127 T 10-11-2016 IPR010071 Amino acid adenylation domain A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 SUPERFAMILY SSF47336 4533 4607 1.14E-18 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1590 1605 - T 10-11-2016 IPR006162 Phosphopantetheine attachment site A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 Pfam PF13745 HxxPF-repeated domain 917 1004 7.5E-24 T 10-11-2016 A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1200 1211 - T 10-11-2016 IPR020845 AMP-binding, conserved site A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 SUPERFAMILY SSF52777 3761 4004 1.83E-57 T 10-11-2016 A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 ProSitePatterns PS00455 Putative AMP-binding domain signature. 4178 4189 - T 10-11-2016 IPR020845 AMP-binding, conserved site A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 SUPERFAMILY SSF52777 1826 2069 4.89E-40 T 10-11-2016 A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 ProSitePatterns PS00012 Phosphopantetheine attachment site. 535 550 - T 10-11-2016 IPR006162 Phosphopantetheine attachment site A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 Gene3D G3DSA:3.40.50.980 4209 4343 6.5E-31 T 10-11-2016 A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 Gene3D G3DSA:3.40.50.980 1232 1365 2.4E-33 T 10-11-2016 A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 Gene3D G3DSA:3.40.50.980 2716 2852 2.2E-34 T 10-11-2016 A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 SUPERFAMILY SSF47336 1558 1628 3.14E-18 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 Gene3D G3DSA:3.40.50.980 4032 4201 4.2E-47 T 10-11-2016 A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 Gene3D G3DSA:3.40.50.980 1051 1222 7.5E-41 T 10-11-2016 A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 Gene3D G3DSA:3.40.50.980 9 162 3.1E-49 T 10-11-2016 A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 Gene3D G3DSA:3.40.50.980 2548 2715 5.9E-51 T 10-11-2016 A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 SUPERFAMILY SSF52777 785 1021 1.06E-48 T 10-11-2016 A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 Pfam PF00668 Condensation domain 2101 2395 3.8E-66 T 10-11-2016 IPR001242 Condensation domain A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 Pfam PF00668 Condensation domain 1653 1940 4.2E-44 T 10-11-2016 IPR001242 Condensation domain A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 Pfam PF00668 Condensation domain 3584 3878 1.2E-65 T 10-11-2016 IPR001242 Condensation domain A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 Pfam PF00668 Condensation domain 3135 3422 1.9E-43 T 10-11-2016 IPR001242 Condensation domain A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 Pfam PF00668 Condensation domain 593 893 5.2E-64 T 10-11-2016 IPR001242 Condensation domain A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 SUPERFAMILY SSF52777 596 775 3.56E-49 T 10-11-2016 A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2694 2705 - T 10-11-2016 IPR020845 AMP-binding, conserved site A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3074 3089 - T 10-11-2016 IPR006162 Phosphopantetheine attachment site A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 Pfam PF13193 AMP-binding enzyme C-terminal domain 4438 4514 7.2E-9 T 10-11-2016 IPR025110 AMP-binding enzyme C-terminal domain A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 Pfam PF13193 AMP-binding enzyme C-terminal domain 409 485 2.8E-12 T 10-11-2016 IPR025110 AMP-binding enzyme C-terminal domain A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 Pfam PF13193 AMP-binding enzyme C-terminal domain 1461 1538 8.7E-13 T 10-11-2016 IPR025110 AMP-binding enzyme C-terminal domain A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 Pfam PF13193 AMP-binding enzyme C-terminal domain 2949 3024 2.5E-13 T 10-11-2016 IPR025110 AMP-binding enzyme C-terminal domain A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 SUPERFAMILY SSF52777 3582 3776 1.67E-44 T 10-11-2016 A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 SUPERFAMILY SSF52777 2278 2525 3.72E-62 T 10-11-2016 A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 SMART SM00823 Phosphopantetheine attachment site 1566 1634 0.005 T 10-11-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 SMART SM00823 Phosphopantetheine attachment site 3050 3118 0.0011 T 10-11-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 SMART SM00823 Phosphopantetheine attachment site 4541 4610 9.4E-6 T 10-11-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 SMART SM00823 Phosphopantetheine attachment site 511 580 0.0097 T 10-11-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 Gene3D G3DSA:3.40.50.980 163 303 3.5E-36 T 10-11-2016 A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 SUPERFAMILY SSF52777 3130 3321 4.78E-26 T 10-11-2016 A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 Pfam PF00550 Phosphopantetheine attachment site 1568 1628 2.0E-9 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 Pfam PF00550 Phosphopantetheine attachment site 3052 3112 1.1E-11 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 Pfam PF00550 Phosphopantetheine attachment site 4543 4606 1.0E-14 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 Pfam PF00550 Phosphopantetheine attachment site 513 574 6.7E-14 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 SUPERFAMILY SSF56801 1017 1579 4.06E-144 T 10-11-2016 A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 Gene3D G3DSA:3.30.559.10 3659 3753 2.7E-4 T 10-11-2016 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 Gene3D G3DSA:3.30.300.30 1449 1570 3.4E-41 T 10-11-2016 A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 Gene3D G3DSA:3.30.300.30 4426 4544 1.3E-38 T 10-11-2016 A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 Gene3D G3DSA:3.30.300.30 396 515 1.4E-38 T 10-11-2016 A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 Gene3D G3DSA:3.30.300.30 2936 3054 1.0E-40 T 10-11-2016 A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 SUPERFAMILY SSF47336 3043 3112 1.24E-18 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 SUPERFAMILY SSF56801 4028 4553 3.92E-149 T 10-11-2016 A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 SMART SM01294 4542 4606 0.0064 T 10-11-2016 A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 Pfam PF00501 AMP-binding enzyme 4037 4430 3.9E-95 T 10-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 Pfam PF00501 AMP-binding enzyme 2555 2941 3.4E-94 T 10-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 Pfam PF00501 AMP-binding enzyme 1056 1453 1.0E-89 T 10-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 Pfam PF00501 AMP-binding enzyme 18 401 6.0E-92 T 10-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 SUPERFAMILY SSF52777 3309 3552 2.67E-39 T 10-11-2016 A4G23_RS21775 77be5f1ab4441fe029036e715226bd27 4618 SUPERFAMILY SSF52777 1648 1840 2.22E-26 T 10-11-2016 A4G23_RS01615 4e7f365d2ec9e9c5bc85d00e12b2c31b 189 SUPERFAMILY SSF141571 12 186 1.31E-37 T 10-11-2016 A4G23_RS01615 4e7f365d2ec9e9c5bc85d00e12b2c31b 189 Pfam PF00805 Pentapeptide repeats (8 copies) 40 77 0.0015 T 10-11-2016 IPR001646 Pentapeptide repeat A4G23_RS01615 4e7f365d2ec9e9c5bc85d00e12b2c31b 189 Pfam PF00805 Pentapeptide repeats (8 copies) 120 158 1.0E-11 T 10-11-2016 IPR001646 Pentapeptide repeat A4G23_RS25105 e52fb705115af8cdcf3e29ac1a25876f 331 ProSitePatterns PS01044 Squalene and phytoene synthases signature 1. 142 157 - T 10-11-2016 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A4G23_RS25105 e52fb705115af8cdcf3e29ac1a25876f 331 Pfam PF00494 Squalene/phytoene synthase 29 291 9.0E-63 T 10-11-2016 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 A4G23_RS25105 e52fb705115af8cdcf3e29ac1a25876f 331 SUPERFAMILY SSF48576 19 303 2.25E-72 T 10-11-2016 IPR008949 Isoprenoid synthase domain A4G23_RS25105 e52fb705115af8cdcf3e29ac1a25876f 331 ProSitePatterns PS01045 Squalene and phytoene synthases signature 2. 174 199 - T 10-11-2016 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A4G23_RS25105 e52fb705115af8cdcf3e29ac1a25876f 331 Gene3D G3DSA:1.10.600.10 15 302 3.3E-74 T 10-11-2016 IPR008949 Isoprenoid synthase domain A4G23_RS15285 6aa060147165aed3917389a2650b47a3 199 Gene3D G3DSA:3.30.70.560 34 185 6.1E-54 T 10-11-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 A4G23_RS15285 6aa060147165aed3917389a2650b47a3 199 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 34 165 5.4E-43 T 10-11-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 A4G23_RS15285 6aa060147165aed3917389a2650b47a3 199 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 120 131 - T 10-11-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 A4G23_RS15285 6aa060147165aed3917389a2650b47a3 199 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 35 165 2.5E-37 T 10-11-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 A4G23_RS15285 6aa060147165aed3917389a2650b47a3 199 SUPERFAMILY SSF55083 34 175 3.27E-48 T 10-11-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 A4G23_RS08350 f677bcff38946b9038f99d19edb65c38 409 SUPERFAMILY SSF55729 6 303 6.92E-61 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS08350 f677bcff38946b9038f99d19edb65c38 409 Gene3D G3DSA:3.30.1050.10 290 396 6.0E-26 T 10-11-2016 IPR003033 SCP2 sterol-binding domain A4G23_RS08350 f677bcff38946b9038f99d19edb65c38 409 Pfam PF13527 Acetyltransferase (GNAT) domain 6 130 4.2E-35 T 10-11-2016 A4G23_RS08350 f677bcff38946b9038f99d19edb65c38 409 Pfam PF13530 Sterol carrier protein domain 180 405 2.0E-51 T 10-11-2016 IPR025559 Enhanced intracellular survival protein domain A4G23_RS08350 f677bcff38946b9038f99d19edb65c38 409 Gene3D G3DSA:3.40.630.30 129 288 4.3E-15 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS08350 f677bcff38946b9038f99d19edb65c38 409 Gene3D G3DSA:3.40.630.30 3 128 9.0E-25 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS08350 f677bcff38946b9038f99d19edb65c38 409 SUPERFAMILY SSF55718 304 409 1.41E-26 T 10-11-2016 IPR003033 SCP2 sterol-binding domain A4G23_RS08350 f677bcff38946b9038f99d19edb65c38 409 Hamap MF_01812 UPF0256 protein . 1 409 43.054 T 10-11-2016 IPR022902 Uncharacterised protein family UPF0256 A4G23_RS16025 f8786794ddd6667a518264f19ddb935c 428 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 161 176 1.4E-11 T 10-11-2016 A4G23_RS16025 f8786794ddd6667a518264f19ddb935c 428 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 11 33 1.4E-11 T 10-11-2016 A4G23_RS16025 f8786794ddd6667a518264f19ddb935c 428 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 299 314 1.4E-11 T 10-11-2016 A4G23_RS16025 f8786794ddd6667a518264f19ddb935c 428 Pfam PF01494 FAD binding domain 10 187 8.7E-13 T 10-11-2016 IPR002938 FAD-binding domain GO:0071949 A4G23_RS16025 f8786794ddd6667a518264f19ddb935c 428 SUPERFAMILY SSF51905 289 382 5.72E-46 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS16025 f8786794ddd6667a518264f19ddb935c 428 SUPERFAMILY SSF51905 8 192 5.72E-46 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS16025 f8786794ddd6667a518264f19ddb935c 428 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 11 334 1.9E-88 T 10-11-2016 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 A4G23_RS16025 f8786794ddd6667a518264f19ddb935c 428 Gene3D G3DSA:3.50.50.60 8 177 1.1E-23 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS16025 f8786794ddd6667a518264f19ddb935c 428 Gene3D G3DSA:3.30.9.10 178 341 9.8E-53 T 10-11-2016 A4G23_RS17605 49f39b4465e4193ecd8d6099c928cbad 425 SUPERFAMILY SSF54680 321 416 1.7E-25 T 10-11-2016 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A4G23_RS17605 49f39b4465e4193ecd8d6099c928cbad 425 SMART SM00941 334 408 1.0E-32 T 10-11-2016 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A4G23_RS17605 49f39b4465e4193ecd8d6099c928cbad 425 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 335 407 5.7E-23 T 10-11-2016 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A4G23_RS17605 49f39b4465e4193ecd8d6099c928cbad 425 SUPERFAMILY SSF52418 69 316 1.7E-80 T 10-11-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A4G23_RS17605 49f39b4465e4193ecd8d6099c928cbad 425 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 4 407 7.7E-166 T 10-11-2016 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 A4G23_RS17605 49f39b4465e4193ecd8d6099c928cbad 425 Gene3D G3DSA:1.20.970.10 1 67 1.2E-27 T 10-11-2016 A4G23_RS17605 49f39b4465e4193ecd8d6099c928cbad 425 Gene3D G3DSA:3.40.1030.10 70 317 4.1E-108 T 10-11-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A4G23_RS17605 49f39b4465e4193ecd8d6099c928cbad 425 Pfam PF00591 Glycosyl transferase family, a/b domain 77 286 1.5E-33 T 10-11-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A4G23_RS17605 49f39b4465e4193ecd8d6099c928cbad 425 Pfam PF02885 Glycosyl transferase family, helical bundle domain 6 66 5.4E-19 T 10-11-2016 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 A4G23_RS17605 49f39b4465e4193ecd8d6099c928cbad 425 Gene3D G3DSA:3.90.1170.30 318 409 4.1E-31 T 10-11-2016 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A4G23_RS17605 49f39b4465e4193ecd8d6099c928cbad 425 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 110 125 - T 10-11-2016 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A4G23_RS17605 49f39b4465e4193ecd8d6099c928cbad 425 SUPERFAMILY SSF47648 1 69 6.8E-20 T 10-11-2016 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 A4G23_RS17605 49f39b4465e4193ecd8d6099c928cbad 425 PIRSF PIRSF000478 1 423 1.7E-150 T 10-11-2016 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A4G23_RS07175 1943b5fed7d7fdafd83511ed61303ac7 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 7.3E-8 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS07175 1943b5fed7d7fdafd83511ed61303ac7 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 7.3E-8 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS07175 1943b5fed7d7fdafd83511ed61303ac7 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 68 2.4E-16 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS07175 1943b5fed7d7fdafd83511ed61303ac7 198 SUPERFAMILY SSF46689 11 84 3.09E-18 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS07175 1943b5fed7d7fdafd83511ed61303ac7 198 Gene3D G3DSA:1.10.357.10 10 195 3.5E-31 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS14540 03144032444d0a7377baa8dc316eb5c6 414 SUPERFAMILY SSF53383 2 397 3.75E-78 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS14540 03144032444d0a7377baa8dc316eb5c6 414 Gene3D G3DSA:3.90.1150.10 257 400 6.3E-48 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS14540 03144032444d0a7377baa8dc316eb5c6 414 PIRSF PIRSF038800 1 403 7.6E-128 T 10-11-2016 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 A4G23_RS14540 03144032444d0a7377baa8dc316eb5c6 414 Pfam PF00266 Aminotransferase class-V 151 319 3.7E-13 T 10-11-2016 IPR000192 Aminotransferase class V domain A4G23_RS14540 03144032444d0a7377baa8dc316eb5c6 414 TIGRFAM TIGR01814 kynureninase: kynureninase 1 394 2.4E-78 T 10-11-2016 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 A4G23_RS14540 03144032444d0a7377baa8dc316eb5c6 414 Gene3D G3DSA:3.40.640.10 117 256 6.9E-18 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS14540 03144032444d0a7377baa8dc316eb5c6 414 Hamap MF_01970 Kynureninase [kynU]. 1 395 32.533 T 10-11-2016 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 A4G23_RS11780 a9d57f63297b439947db1e4d80a4b853 187 Pfam PF05685 Putative restriction endonuclease 14 179 2.1E-17 T 10-11-2016 IPR008538 Domain of unknown function DUF820 A4G23_RS11780 a9d57f63297b439947db1e4d80a4b853 187 SUPERFAMILY SSF52980 8 161 8.04E-17 T 10-11-2016 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A4G23_RS11780 a9d57f63297b439947db1e4d80a4b853 187 Gene3D G3DSA:3.90.1570.10 8 165 1.1E-16 T 10-11-2016 IPR012296 Nuclease, putative, TT1808 A4G23_RS11185 669b1530011d64523e8e20734e1c42bc 166 SUPERFAMILY SSF110087 22 161 3.79E-26 T 10-11-2016 IPR007410 DR1885-like metal-binding protein A4G23_RS11185 669b1530011d64523e8e20734e1c42bc 166 Pfam PF04314 Protein of unknown function (DUF461) 53 152 2.2E-19 T 10-11-2016 IPR007410 DR1885-like metal-binding protein A4G23_RS20590 11a98378a952ca2dc15559c0c74ed4c7 278 SUPERFAMILY SSF46934 3 55 9.07E-16 T 10-11-2016 IPR009060 UBA-like GO:0005515 A4G23_RS20590 11a98378a952ca2dc15559c0c74ed4c7 278 Gene3D G3DSA:1.10.8.10 3 55 5.5E-24 T 10-11-2016 A4G23_RS20590 11a98378a952ca2dc15559c0c74ed4c7 278 Pfam PF00889 Elongation factor TS 73 277 1.4E-61 T 10-11-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A4G23_RS20590 11a98378a952ca2dc15559c0c74ed4c7 278 SUPERFAMILY SSF54713 150 277 9.42E-38 T 10-11-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A4G23_RS20590 11a98378a952ca2dc15559c0c74ed4c7 278 Hamap MF_00050 Elongation factor Ts [tsf]. 1 278 63.553 T 10-11-2016 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A4G23_RS20590 11a98378a952ca2dc15559c0c74ed4c7 278 Gene3D G3DSA:1.10.286.20 198 241 1.5E-18 T 10-11-2016 A4G23_RS20590 11a98378a952ca2dc15559c0c74ed4c7 278 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 277 1.0E-73 T 10-11-2016 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A4G23_RS20590 11a98378a952ca2dc15559c0c74ed4c7 278 Gene3D G3DSA:3.30.479.20 152 193 2.0E-22 T 10-11-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A4G23_RS20590 11a98378a952ca2dc15559c0c74ed4c7 278 Gene3D G3DSA:3.30.479.20 242 277 2.0E-22 T 10-11-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A4G23_RS20590 11a98378a952ca2dc15559c0c74ed4c7 278 SUPERFAMILY SSF54713 57 147 8.9E-20 T 10-11-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A4G23_RS20590 11a98378a952ca2dc15559c0c74ed4c7 278 ProSitePatterns PS01126 Elongation factor Ts signature 1. 12 27 - T 10-11-2016 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A4G23_RS20590 11a98378a952ca2dc15559c0c74ed4c7 278 Gene3D G3DSA:3.30.479.20 57 150 2.8E-22 T 10-11-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A4G23_RS20590 11a98378a952ca2dc15559c0c74ed4c7 278 ProSitePatterns PS01127 Elongation factor Ts signature 2. 77 87 - T 10-11-2016 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A4G23_RS07545 9443afe1c8a61165f670ec04bd7c9ef5 339 Gene3D G3DSA:3.90.180.10 5 143 1.2E-51 T 10-11-2016 IPR011032 GroES-like A4G23_RS07545 9443afe1c8a61165f670ec04bd7c9ef5 339 Pfam PF00107 Zinc-binding dehydrogenase 161 288 1.7E-23 T 10-11-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A4G23_RS07545 9443afe1c8a61165f670ec04bd7c9ef5 339 Gene3D G3DSA:3.40.50.720 144 305 1.1E-69 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS07545 9443afe1c8a61165f670ec04bd7c9ef5 339 Pfam PF16884 N-terminal domain of oxidoreductase 9 113 2.3E-39 T 10-11-2016 A4G23_RS07545 9443afe1c8a61165f670ec04bd7c9ef5 339 SMART SM00829 21 335 7.2E-7 T 10-11-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A4G23_RS07545 9443afe1c8a61165f670ec04bd7c9ef5 339 SUPERFAMILY SSF51735 126 302 8.23E-50 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS07545 9443afe1c8a61165f670ec04bd7c9ef5 339 SUPERFAMILY SSF50129 7 144 6.06E-40 T 10-11-2016 IPR011032 GroES-like A4G23_RS14595 c8a9e0d4a53bde0ce0b9ba2eb3a5f18f 574 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 30 114 1.3E-6 T 10-11-2016 IPR000014 PAS domain A4G23_RS14595 c8a9e0d4a53bde0ce0b9ba2eb3a5f18f 574 SUPERFAMILY SSF55781 173 336 1.18E-15 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS14595 c8a9e0d4a53bde0ce0b9ba2eb3a5f18f 574 SMART SM00331 351 572 3.9E-33 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS14595 c8a9e0d4a53bde0ce0b9ba2eb3a5f18f 574 Gene3D G3DSA:3.30.450.20 18 119 1.4E-11 T 10-11-2016 A4G23_RS14595 c8a9e0d4a53bde0ce0b9ba2eb3a5f18f 574 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 381 572 5.3E-44 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS14595 c8a9e0d4a53bde0ce0b9ba2eb3a5f18f 574 SMART SM00065 173 334 1.3E-7 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS14595 c8a9e0d4a53bde0ce0b9ba2eb3a5f18f 574 SMART SM00091 20 86 4.5E-8 T 10-11-2016 IPR000014 PAS domain A4G23_RS14595 c8a9e0d4a53bde0ce0b9ba2eb3a5f18f 574 Gene3D G3DSA:3.30.450.40 161 332 2.8E-27 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS14595 c8a9e0d4a53bde0ce0b9ba2eb3a5f18f 574 SUPERFAMILY SSF55785 18 119 2.39E-11 T 10-11-2016 IPR000014 PAS domain A4G23_RS14595 c8a9e0d4a53bde0ce0b9ba2eb3a5f18f 574 SUPERFAMILY SSF81606 367 572 1.83E-11 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS14595 c8a9e0d4a53bde0ce0b9ba2eb3a5f18f 574 Pfam PF00989 PAS fold 26 73 3.7E-7 T 10-11-2016 IPR013767 PAS fold GO:0006355 A4G23_RS14595 c8a9e0d4a53bde0ce0b9ba2eb3a5f18f 574 Pfam PF01590 GAF domain 173 324 4.8E-9 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS02700 6a2083bda8e8d5fcde204a49e4335f2a 545 Gene3D G3DSA:3.50.50.60 8 73 2.8E-54 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS02700 6a2083bda8e8d5fcde204a49e4335f2a 545 Gene3D G3DSA:3.50.50.60 110 195 2.8E-54 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS02700 6a2083bda8e8d5fcde204a49e4335f2a 545 Gene3D G3DSA:3.50.50.60 281 362 2.8E-54 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS02700 6a2083bda8e8d5fcde204a49e4335f2a 545 SUPERFAMILY SSF51905 280 372 6.28E-57 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS02700 6a2083bda8e8d5fcde204a49e4335f2a 545 SUPERFAMILY SSF51905 8 190 6.28E-57 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS02700 6a2083bda8e8d5fcde204a49e4335f2a 545 Pfam PF01494 FAD binding domain 8 356 2.6E-74 T 10-11-2016 IPR002938 FAD-binding domain GO:0071949 A4G23_RS02700 6a2083bda8e8d5fcde204a49e4335f2a 545 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 326 344 8.3E-43 T 10-11-2016 A4G23_RS02700 6a2083bda8e8d5fcde204a49e4335f2a 545 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 344 360 8.3E-43 T 10-11-2016 A4G23_RS02700 6a2083bda8e8d5fcde204a49e4335f2a 545 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 169 184 8.3E-43 T 10-11-2016 A4G23_RS02700 6a2083bda8e8d5fcde204a49e4335f2a 545 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 293 308 8.3E-43 T 10-11-2016 A4G23_RS02700 6a2083bda8e8d5fcde204a49e4335f2a 545 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 308 324 8.3E-43 T 10-11-2016 A4G23_RS02700 6a2083bda8e8d5fcde204a49e4335f2a 545 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 9 31 8.3E-43 T 10-11-2016 A4G23_RS10425 d274ac29e4f38e396c7875bdf5c7f481 930 Pfam PF09586 Bacterial membrane protein YfhO 8 373 3.4E-58 T 10-11-2016 IPR018580 Uncharacterised protein family YfhO A4G23_RS02470 994ac7f038d60b43d7b5b35b9c595602 408 Gene3D G3DSA:1.20.140.10 223 404 1.3E-65 T 10-11-2016 A4G23_RS02470 994ac7f038d60b43d7b5b35b9c595602 408 Gene3D G3DSA:1.10.540.10 3 115 1.0E-24 T 10-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 A4G23_RS02470 994ac7f038d60b43d7b5b35b9c595602 408 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 126 223 2.9E-24 T 10-11-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 A4G23_RS02470 994ac7f038d60b43d7b5b35b9c595602 408 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 258 402 3.1E-52 T 10-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4G23_RS02470 994ac7f038d60b43d7b5b35b9c595602 408 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 115 1.5E-14 T 10-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 A4G23_RS02470 994ac7f038d60b43d7b5b35b9c595602 408 SUPERFAMILY SSF47203 258 405 4.03E-54 T 10-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4G23_RS02470 994ac7f038d60b43d7b5b35b9c595602 408 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 361 380 - T 10-11-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A4G23_RS02470 994ac7f038d60b43d7b5b35b9c595602 408 Gene3D G3DSA:2.40.110.10 125 222 1.1E-35 T 10-11-2016 A4G23_RS02470 994ac7f038d60b43d7b5b35b9c595602 408 SUPERFAMILY SSF56645 4 234 5.76E-58 T 10-11-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 A4G23_RS25045 0318edaeb60dd9b9fba41bab3cbb3b3e 192 Gene3D G3DSA:1.20.1260.10 6 163 2.3E-46 T 10-11-2016 IPR012347 Ferritin-related A4G23_RS25045 0318edaeb60dd9b9fba41bab3cbb3b3e 192 PIRSF PIRSF005900 3 168 1.2E-51 T 10-11-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 A4G23_RS25045 0318edaeb60dd9b9fba41bab3cbb3b3e 192 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 140 158 8.7E-12 T 10-11-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 A4G23_RS25045 0318edaeb60dd9b9fba41bab3cbb3b3e 192 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 45 61 8.7E-12 T 10-11-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 A4G23_RS25045 0318edaeb60dd9b9fba41bab3cbb3b3e 192 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 69 85 8.7E-12 T 10-11-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 A4G23_RS25045 0318edaeb60dd9b9fba41bab3cbb3b3e 192 Pfam PF00210 Ferritin-like domain 24 163 1.9E-24 T 10-11-2016 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 A4G23_RS25045 0318edaeb60dd9b9fba41bab3cbb3b3e 192 SUPERFAMILY SSF47240 5 163 4.06E-42 T 10-11-2016 IPR009078 Ferritin-like superfamily A4G23_RS25045 0318edaeb60dd9b9fba41bab3cbb3b3e 192 ProSitePatterns PS00818 Dps protein family signature 1. 45 61 - T 10-11-2016 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 A4G23_RS13645 e1eb9d847e98db2f0cdd709f06add6a9 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 9.2E-10 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS13645 e1eb9d847e98db2f0cdd709f06add6a9 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 9.2E-10 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS13645 e1eb9d847e98db2f0cdd709f06add6a9 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 9.2E-10 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS13645 e1eb9d847e98db2f0cdd709f06add6a9 297 SUPERFAMILY SSF46785 1 79 1.01E-21 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS13645 e1eb9d847e98db2f0cdd709f06add6a9 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 1.3E-21 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS13645 e1eb9d847e98db2f0cdd709f06add6a9 297 SUPERFAMILY SSF53850 82 293 9.59E-21 T 10-11-2016 A4G23_RS13645 e1eb9d847e98db2f0cdd709f06add6a9 297 Gene3D G3DSA:3.40.190.10 127 173 1.7E-4 T 10-11-2016 A4G23_RS13645 e1eb9d847e98db2f0cdd709f06add6a9 297 Gene3D G3DSA:3.40.190.10 174 259 1.0E-16 T 10-11-2016 A4G23_RS13645 e1eb9d847e98db2f0cdd709f06add6a9 297 Pfam PF03466 LysR substrate binding domain 90 293 6.1E-22 T 10-11-2016 IPR005119 LysR, substrate-binding A4G23_RS13645 e1eb9d847e98db2f0cdd709f06add6a9 297 Gene3D G3DSA:1.10.10.10 1 80 2.6E-25 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS00860 0baa649b61b85772816643a3cc96482f 84 SUPERFAMILY SSF54292 3 81 3.8E-18 T 10-11-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A4G23_RS00860 0baa649b61b85772816643a3cc96482f 84 Gene3D G3DSA:3.10.20.30 16 71 5.1E-4 T 10-11-2016 IPR012675 Beta-grasp domain A4G23_RS00860 0baa649b61b85772816643a3cc96482f 84 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 4 79 1.8E-23 T 10-11-2016 A4G23_RS05825 db1ca51367685cf4b045e833b0500e18 203 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 4 187 2.2E-49 T 10-11-2016 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24 A4G23_RS05825 db1ca51367685cf4b045e833b0500e18 203 SUPERFAMILY SSF52540 1 192 3.43E-40 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05825 db1ca51367685cf4b045e833b0500e18 203 Pfam PF01121 Dephospho-CoA kinase 3 179 2.7E-57 T 10-11-2016 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24 A4G23_RS05825 db1ca51367685cf4b045e833b0500e18 203 Gene3D G3DSA:3.40.50.300 1 199 1.3E-72 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05825 db1ca51367685cf4b045e833b0500e18 203 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 1 196 27.361 T 10-11-2016 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24 A4G23_RS06255 c14f4731cd9f39011e13f72ca8324d56 356 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 17 345 1.7E-99 T 10-11-2016 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4G23_RS06255 c14f4731cd9f39011e13f72ca8324d56 356 Pfam PF00953 Glycosyl transferase family 4 82 275 1.3E-37 T 10-11-2016 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 A4G23_RS06255 c14f4731cd9f39011e13f72ca8324d56 356 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 46 55 6.7E-4 T 10-11-2016 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4G23_RS06255 c14f4731cd9f39011e13f72ca8324d56 356 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 3 349 24.062 T 10-11-2016 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4G23_RS06255 c14f4731cd9f39011e13f72ca8324d56 356 ProSitePatterns PS01347 MraY family signature 1. 46 58 - T 10-11-2016 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4G23_RS06255 c14f4731cd9f39011e13f72ca8324d56 356 ProSitePatterns PS01348 MraY family signature 2. 174 185 - T 10-11-2016 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4G23_RS18085 98bc7ca14b4195edfeb57049b5d9a659 575 Pfam PF02018 Carbohydrate binding domain 47 161 1.4E-13 T 10-11-2016 IPR003305 Carbohydrate-binding, CenC-like GO:0016798 A4G23_RS18085 98bc7ca14b4195edfeb57049b5d9a659 575 Gene3D G3DSA:2.60.120.260 45 177 2.4E-10 T 10-11-2016 IPR008979 Galactose-binding domain-like A4G23_RS18085 98bc7ca14b4195edfeb57049b5d9a659 575 SUPERFAMILY SSF49785 45 178 6.38E-11 T 10-11-2016 IPR008979 Galactose-binding domain-like A4G23_RS18085 98bc7ca14b4195edfeb57049b5d9a659 575 Gene3D G3DSA:3.20.20.80 285 564 1.8E-58 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS18085 98bc7ca14b4195edfeb57049b5d9a659 575 SMART SM00060 191 261 5.2E-13 T 10-11-2016 IPR003961 Fibronectin type III GO:0005515 A4G23_RS18085 98bc7ca14b4195edfeb57049b5d9a659 575 SUPERFAMILY SSF51445 283 563 3.04E-54 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS18085 98bc7ca14b4195edfeb57049b5d9a659 575 PRINTS PR00014 Fibronectin type III repeat signature 248 262 7.3E-5 T 10-11-2016 A4G23_RS18085 98bc7ca14b4195edfeb57049b5d9a659 575 PRINTS PR00014 Fibronectin type III repeat signature 205 214 7.3E-5 T 10-11-2016 A4G23_RS18085 98bc7ca14b4195edfeb57049b5d9a659 575 PRINTS PR00014 Fibronectin type III repeat signature 230 248 7.3E-5 T 10-11-2016 A4G23_RS18085 98bc7ca14b4195edfeb57049b5d9a659 575 SUPERFAMILY SSF49265 188 276 3.17E-18 T 10-11-2016 IPR003961 Fibronectin type III GO:0005515 A4G23_RS18085 98bc7ca14b4195edfeb57049b5d9a659 575 Pfam PF00704 Glycosyl hydrolases family 18 289 556 3.0E-29 T 10-11-2016 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0004553|GO:0005975 A4G23_RS18085 98bc7ca14b4195edfeb57049b5d9a659 575 SMART SM00636 286 556 1.3E-6 T 10-11-2016 IPR011583 Chitinase II GO:0004568|GO:0006032 A4G23_RS18085 98bc7ca14b4195edfeb57049b5d9a659 575 Gene3D G3DSA:2.60.40.10 190 267 1.7E-20 T 10-11-2016 IPR013783 Immunoglobulin-like fold A4G23_RS18085 98bc7ca14b4195edfeb57049b5d9a659 575 Pfam PF00041 Fibronectin type III domain 194 264 1.8E-8 T 10-11-2016 IPR003961 Fibronectin type III GO:0005515 A4G23_RS10560 87faf6dd0c5f995b6169ae846d47e13a 198 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 8 190 32.519 T 10-11-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 A4G23_RS10560 87faf6dd0c5f995b6169ae846d47e13a 198 Pfam PF01195 Peptidyl-tRNA hydrolase 10 195 1.7E-50 T 10-11-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 A4G23_RS10560 87faf6dd0c5f995b6169ae846d47e13a 198 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 120 130 - T 10-11-2016 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 A4G23_RS10560 87faf6dd0c5f995b6169ae846d47e13a 198 Gene3D G3DSA:3.40.50.1470 5 197 7.9E-69 T 10-11-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 A4G23_RS10560 87faf6dd0c5f995b6169ae846d47e13a 198 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 10 198 3.4E-52 T 10-11-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 A4G23_RS10560 87faf6dd0c5f995b6169ae846d47e13a 198 SUPERFAMILY SSF53178 8 197 1.96E-63 T 10-11-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 A4G23_RS10560 87faf6dd0c5f995b6169ae846d47e13a 198 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 21 34 - T 10-11-2016 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 A4G23_RS00310 d009d1600948623844f7537a1e7d2a83 432 Gene3D G3DSA:1.20.1250.20 264 420 4.3E-12 T 10-11-2016 A4G23_RS00310 d009d1600948623844f7537a1e7d2a83 432 SUPERFAMILY SSF103473 40 421 2.75E-44 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS00310 d009d1600948623844f7537a1e7d2a83 432 Gene3D G3DSA:1.20.1250.20 40 224 8.4E-22 T 10-11-2016 A4G23_RS00310 d009d1600948623844f7537a1e7d2a83 432 Pfam PF05977 Transmembrane secretion effector 30 415 1.9E-41 T 10-11-2016 IPR010290 Transmembrane secretion effector A4G23_RS04365 dc343883f4fbadb1441c943496b831c8 1174 PIRSF PIRSF000381 15 1174 0.0 T 10-11-2016 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0008898|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4G23_RS04365 dc343883f4fbadb1441c943496b831c8 1174 SUPERFAMILY SSF51717 354 625 8.9E-74 T 10-11-2016 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4G23_RS04365 dc343883f4fbadb1441c943496b831c8 1174 SUPERFAMILY SSF56507 900 1173 3.53E-95 T 10-11-2016 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4G23_RS04365 dc343883f4fbadb1441c943496b831c8 1174 Gene3D G3DSA:3.20.20.330 20 361 4.8E-103 T 10-11-2016 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 A4G23_RS04365 dc343883f4fbadb1441c943496b831c8 1174 Gene3D G3DSA:3.20.20.20 362 623 1.9E-84 T 10-11-2016 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4G23_RS04365 dc343883f4fbadb1441c943496b831c8 1174 Pfam PF00809 Pterin binding enzyme 357 593 8.4E-45 T 10-11-2016 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4G23_RS04365 dc343883f4fbadb1441c943496b831c8 1174 Pfam PF02310 B12 binding domain 740 857 3.8E-20 T 10-11-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A4G23_RS04365 dc343883f4fbadb1441c943496b831c8 1174 Gene3D G3DSA:3.40.50.280 737 867 2.4E-46 T 10-11-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A4G23_RS04365 dc343883f4fbadb1441c943496b831c8 1174 Gene3D G3DSA:3.10.196.10 957 1172 8.5E-73 T 10-11-2016 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4G23_RS04365 dc343883f4fbadb1441c943496b831c8 1174 SUPERFAMILY SSF82282 22 396 1.83E-102 T 10-11-2016 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 A4G23_RS04365 dc343883f4fbadb1441c943496b831c8 1174 Pfam PF02574 Homocysteine S-methyltransferase 31 322 1.2E-65 T 10-11-2016 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 A4G23_RS04365 dc343883f4fbadb1441c943496b831c8 1174 SUPERFAMILY SSF47644 650 733 2.09E-24 T 10-11-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4G23_RS04365 dc343883f4fbadb1441c943496b831c8 1174 TIGRFAM TIGR02082 metH: methionine synthase 27 1172 0.0 T 10-11-2016 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0008898|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4G23_RS04365 dc343883f4fbadb1441c943496b831c8 1174 SMART SM01018 652 734 1.6E-41 T 10-11-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4G23_RS04365 dc343883f4fbadb1441c943496b831c8 1174 SUPERFAMILY SSF52242 735 869 5.36E-38 T 10-11-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A4G23_RS04365 dc343883f4fbadb1441c943496b831c8 1174 Gene3D G3DSA:1.10.1240.10 646 731 3.6E-32 T 10-11-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4G23_RS04365 dc343883f4fbadb1441c943496b831c8 1174 Pfam PF02607 B12 binding domain 655 727 2.9E-26 T 10-11-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4G23_RS04365 dc343883f4fbadb1441c943496b831c8 1174 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 972 1172 2.5E-41 T 10-11-2016 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4G23_RS24185 8a1b6bd82997c8db2f0adccdd60ec5fd 378 Gene3D G3DSA:3.50.50.60 1 202 5.8E-51 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS24185 8a1b6bd82997c8db2f0adccdd60ec5fd 378 Gene3D G3DSA:3.50.50.60 203 313 4.6E-5 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS24185 8a1b6bd82997c8db2f0adccdd60ec5fd 378 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 4 20 4.4E-12 T 10-11-2016 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 A4G23_RS24185 8a1b6bd82997c8db2f0adccdd60ec5fd 378 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 176 190 4.4E-12 T 10-11-2016 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 A4G23_RS24185 8a1b6bd82997c8db2f0adccdd60ec5fd 378 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 292 319 4.4E-12 T 10-11-2016 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 A4G23_RS24185 8a1b6bd82997c8db2f0adccdd60ec5fd 378 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 203 218 4.4E-12 T 10-11-2016 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 A4G23_RS24185 8a1b6bd82997c8db2f0adccdd60ec5fd 378 SUPERFAMILY SSF51905 1 212 4.98E-45 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS24185 8a1b6bd82997c8db2f0adccdd60ec5fd 378 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 133 222 6.5E-14 T 10-11-2016 A4G23_RS24185 8a1b6bd82997c8db2f0adccdd60ec5fd 378 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 8 108 1.7E-9 T 10-11-2016 A4G23_RS24185 8a1b6bd82997c8db2f0adccdd60ec5fd 378 SUPERFAMILY SSF51905 160 308 2.0E-13 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS16665 62473957c2fd49e23eb9bd5c1a272abf 185 ProSitePatterns PS00358 Ribosomal protein L5 signature. 62 78 - T 10-11-2016 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS16665 62473957c2fd49e23eb9bd5c1a272abf 185 SUPERFAMILY SSF55282 8 183 3.77E-75 T 10-11-2016 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS16665 62473957c2fd49e23eb9bd5c1a272abf 185 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 6 184 43.613 T 10-11-2016 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS16665 62473957c2fd49e23eb9bd5c1a272abf 185 Pfam PF00281 Ribosomal protein L5 29 85 1.5E-28 T 10-11-2016 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS16665 62473957c2fd49e23eb9bd5c1a272abf 185 PIRSF PIRSF002161 1 185 1.3E-63 T 10-11-2016 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS16665 62473957c2fd49e23eb9bd5c1a272abf 185 Pfam PF00673 ribosomal L5P family C-terminus 89 182 5.5E-39 T 10-11-2016 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS16665 62473957c2fd49e23eb9bd5c1a272abf 185 Gene3D G3DSA:3.30.1440.10 7 183 2.0E-75 T 10-11-2016 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS25555 3e395ced7e7fe5564e01558436eee06b 214 SMART SM00116 15 63 0.9 T 10-11-2016 IPR000644 CBS domain A4G23_RS25555 3e395ced7e7fe5564e01558436eee06b 214 SMART SM00116 95 143 1.3E-10 T 10-11-2016 IPR000644 CBS domain A4G23_RS25555 3e395ced7e7fe5564e01558436eee06b 214 SUPERFAMILY SSF54631 4 144 5.05E-32 T 10-11-2016 A4G23_RS25555 3e395ced7e7fe5564e01558436eee06b 214 Pfam PF00571 CBS domain 88 142 9.2E-15 T 10-11-2016 IPR000644 CBS domain A4G23_RS25555 3e395ced7e7fe5564e01558436eee06b 214 Pfam PF00571 CBS domain 8 59 5.9E-8 T 10-11-2016 IPR000644 CBS domain A4G23_RS25555 3e395ced7e7fe5564e01558436eee06b 214 Pfam PF04972 BON domain 145 205 2.2E-8 T 10-11-2016 IPR007055 BON domain A4G23_RS25555 3e395ced7e7fe5564e01558436eee06b 214 PIRSF PIRSF036990 6 213 5.4E-57 T 10-11-2016 IPR017080 Uncharacterised conserved protein UCP036990, CBS, BON A4G23_RS25555 3e395ced7e7fe5564e01558436eee06b 214 Gene3D G3DSA:3.20.20.70 5 145 8.1E-31 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS23335 6be74e3220be2c0aced85c07e5433022 388 SUPERFAMILY SSF50998 327 383 2.88E-12 T 10-11-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily A4G23_RS23335 6be74e3220be2c0aced85c07e5433022 388 SUPERFAMILY SSF50998 159 300 2.88E-12 T 10-11-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily A4G23_RS23335 6be74e3220be2c0aced85c07e5433022 388 Gene3D G3DSA:2.130.10.10 240 380 3.9E-9 T 10-11-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 A4G23_RS25680 3e124330fe281fa99d811a390f074f8d 141 SUPERFAMILY SSF50692 1 116 1.12E-49 T 10-11-2016 IPR009010 Aspartate decarboxylase-like domain A4G23_RS25680 3e124330fe281fa99d811a390f074f8d 141 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 130 75.856 T 10-11-2016 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 A4G23_RS25680 3e124330fe281fa99d811a390f074f8d 141 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 114 1.0E-44 T 10-11-2016 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 A4G23_RS25680 3e124330fe281fa99d811a390f074f8d 141 Pfam PF02261 Aspartate decarboxylase 1 114 5.6E-52 T 10-11-2016 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 A4G23_RS25680 3e124330fe281fa99d811a390f074f8d 141 Gene3D G3DSA:2.40.40.20 1 118 1.9E-56 T 10-11-2016 A4G23_RS25680 3e124330fe281fa99d811a390f074f8d 141 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 119 9.0E-50 T 10-11-2016 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 A4G23_RS25680 3e124330fe281fa99d811a390f074f8d 141 PIRSF PIRSF006246 1 134 8.1E-54 T 10-11-2016 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 A4G23_RS15350 804cee21bf6a21ce11250c1e6335983d 399 SUPERFAMILY SSF55874 271 395 2.58E-18 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS15350 804cee21bf6a21ce11250c1e6335983d 399 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 300 396 5.1E-5 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS15350 804cee21bf6a21ce11250c1e6335983d 399 Pfam PF07730 Histidine kinase 188 253 7.8E-21 T 10-11-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4G23_RS15350 804cee21bf6a21ce11250c1e6335983d 399 Gene3D G3DSA:3.30.565.10 272 397 4.1E-8 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS13685 9db5058f760e049b56556fee8b402b4d 591 Pfam PF01964 Radical SAM ThiC family 133 553 3.3E-200 T 10-11-2016 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 A4G23_RS13685 9db5058f760e049b56556fee8b402b4d 591 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 132 556 1.2E-213 T 10-11-2016 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 A4G23_RS13685 9db5058f760e049b56556fee8b402b4d 591 Pfam PF13667 ThiC-associated domain 23 86 1.0E-22 T 10-11-2016 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 A4G23_RS13685 9db5058f760e049b56556fee8b402b4d 591 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 132 559 55.98 T 10-11-2016 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 A4G23_RS21265 b304eef890a385fc102128627eb68158 503 Gene3D G3DSA:1.10.390.10 322 461 8.5E-17 T 10-11-2016 A4G23_RS21265 b304eef890a385fc102128627eb68158 503 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 308 323 9.0E-12 T 10-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4G23_RS21265 b304eef890a385fc102128627eb68158 503 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 153 168 9.0E-12 T 10-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4G23_RS21265 b304eef890a385fc102128627eb68158 503 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 327 339 9.0E-12 T 10-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4G23_RS21265 b304eef890a385fc102128627eb68158 503 SUPERFAMILY SSF55486 225 460 7.08E-49 T 10-11-2016 A4G23_RS21265 b304eef890a385fc102128627eb68158 503 SUPERFAMILY SSF63737 26 216 1.23E-32 T 10-11-2016 A4G23_RS21265 b304eef890a385fc102128627eb68158 503 Pfam PF01433 Peptidase family M1 44 364 3.4E-33 T 10-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4G23_RS12700 3a595d639612e5ff8caddb1c68321f92 184 Gene3D G3DSA:1.10.10.10 21 170 7.1E-36 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS12700 3a595d639612e5ff8caddb1c68321f92 184 Pfam PF12802 MarR family 56 114 2.1E-9 T 10-11-2016 A4G23_RS12700 3a595d639612e5ff8caddb1c68321f92 184 SMART SM00347 51 154 7.7E-22 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS12700 3a595d639612e5ff8caddb1c68321f92 184 PRINTS PR00598 Bacterial regulatory protein MarR family signature 144 164 3.5E-9 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS12700 3a595d639612e5ff8caddb1c68321f92 184 PRINTS PR00598 Bacterial regulatory protein MarR family signature 78 94 3.5E-9 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS12700 3a595d639612e5ff8caddb1c68321f92 184 PRINTS PR00598 Bacterial regulatory protein MarR family signature 95 110 3.5E-9 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS12700 3a595d639612e5ff8caddb1c68321f92 184 PRINTS PR00598 Bacterial regulatory protein MarR family signature 114 130 3.5E-9 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS12700 3a595d639612e5ff8caddb1c68321f92 184 SUPERFAMILY SSF46785 21 168 1.89E-32 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS12700 3a595d639612e5ff8caddb1c68321f92 184 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 88 107 4.5E-5 T 10-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 A4G23_RS12700 3a595d639612e5ff8caddb1c68321f92 184 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 77 88 4.5E-5 T 10-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 A4G23_RS12700 3a595d639612e5ff8caddb1c68321f92 184 ProSitePatterns PS00519 AsnC-type HTH domain signature. 79 105 - T 10-11-2016 IPR019885 Transcription regulator HTH, AsnC-type, conserved site A4G23_RS23065 1c94da0acf189470375a80ed5ffe386a 588 Pfam PF00128 Alpha amylase, catalytic domain 113 195 1.4E-8 T 10-11-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A4G23_RS23065 1c94da0acf189470375a80ed5ffe386a 588 SMART SM00642 99 451 1.3E-7 T 10-11-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A4G23_RS23065 1c94da0acf189470375a80ed5ffe386a 588 SUPERFAMILY SSF51445 79 510 1.41E-103 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS23065 1c94da0acf189470375a80ed5ffe386a 588 TIGRFAM TIGR02402 trehalose_TreZ: malto-oligosyltrehalose trehalohydrolase 3 549 1.2E-223 T 10-11-2016 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00520+3.2.1.14|MetaCyc: PWY-2661|MetaCyc: PWY-6902 A4G23_RS23065 1c94da0acf189470375a80ed5ffe386a 588 Gene3D G3DSA:2.60.40.10 2 82 1.9E-21 T 10-11-2016 IPR013783 Immunoglobulin-like fold A4G23_RS23065 1c94da0acf189470375a80ed5ffe386a 588 Pfam PF11941 Domain of unknown function (DUF3459) 495 584 1.8E-16 T 10-11-2016 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) A4G23_RS23065 1c94da0acf189470375a80ed5ffe386a 588 PIRSF PIRSF006337 1 581 2.6E-221 T 10-11-2016 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00520+3.2.1.14|MetaCyc: PWY-2661|MetaCyc: PWY-6902 A4G23_RS23065 1c94da0acf189470375a80ed5ffe386a 588 Gene3D G3DSA:3.20.20.80 475 509 2.6E-76 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS23065 1c94da0acf189470375a80ed5ffe386a 588 Gene3D G3DSA:3.20.20.80 97 432 2.6E-76 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS23065 1c94da0acf189470375a80ed5ffe386a 588 SUPERFAMILY SSF81296 2 83 9.0E-12 T 10-11-2016 IPR014756 Immunoglobulin E-set A4G23_RS24000 22b88dd6efa97361154e86b4f268ea37 483 SUPERFAMILY SSF75304 18 473 6.54E-126 T 10-11-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4G23_RS24000 22b88dd6efa97361154e86b4f268ea37 483 Pfam PF01425 Amidase 39 463 9.9E-102 T 10-11-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4G23_RS24000 22b88dd6efa97361154e86b4f268ea37 483 Gene3D G3DSA:3.90.1300.10 15 478 2.5E-125 T 10-11-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4G23_RS02200 e1500a5e572886916fa051e9d03062fb 511 PIRSF PIRSF001478 12 509 1.1E-221 T 10-11-2016 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 A4G23_RS02200 e1500a5e572886916fa051e9d03062fb 511 Pfam PF11762 L-arabinose isomerase C-terminal domain 373 485 3.3E-46 T 10-11-2016 IPR024664 L-arabinose isomerase, C-terminal KEGG: 00040+5.3.1.4 A4G23_RS02200 e1500a5e572886916fa051e9d03062fb 511 SUPERFAMILY SSF50443 339 507 1.67E-66 T 10-11-2016 IPR004216 L-fucose/L-arabinose isomerase, C-terminal A4G23_RS02200 e1500a5e572886916fa051e9d03062fb 511 Hamap MF_00519 L-arabinose isomerase [araA]. 11 486 62.333 T 10-11-2016 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 A4G23_RS02200 e1500a5e572886916fa051e9d03062fb 511 SUPERFAMILY SSF53743 15 337 9.16E-110 T 10-11-2016 IPR009015 L-fucose isomerase, N-terminal/central domain GO:0005737|GO:0005996|GO:0016861 A4G23_RS02200 e1500a5e572886916fa051e9d03062fb 511 Pfam PF02610 L-arabinose isomerase 17 368 1.4E-167 T 10-11-2016 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 A4G23_RS02200 e1500a5e572886916fa051e9d03062fb 511 ProDom PD018364 ISOMERASE L-ARABINOSE ARABINOSE METABOLISM CARBOHYDRATE CATABOLISM ARAA 18 314 5.0E-107 T 10-11-2016 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 A4G23_RS11610 fda492ef8080c8d8c5e93ec92f278f4b 353 Gene3D G3DSA:2.130.10.10 51 268 8.3E-8 T 10-11-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 A4G23_RS11610 fda492ef8080c8d8c5e93ec92f278f4b 353 SUPERFAMILY SSF50969 50 281 9.42E-11 T 10-11-2016 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like A4G23_RS14625 d4a7e82a193c985ad854616dc45bfe73 352 SUPERFAMILY SSF46785 5 62 7.61E-9 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS14625 d4a7e82a193c985ad854616dc45bfe73 352 ProSitePatterns PS00894 DeoR-type HTH domain signature. 7 41 - T 10-11-2016 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 A4G23_RS14625 d4a7e82a193c985ad854616dc45bfe73 352 Gene3D G3DSA:1.10.10.10 1 65 5.1E-14 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS14625 d4a7e82a193c985ad854616dc45bfe73 352 Pfam PF08279 HTH domain 21 62 1.8E-10 T 10-11-2016 IPR013196 Helix-turn-helix, type 11 A4G23_RS14625 d4a7e82a193c985ad854616dc45bfe73 352 Pfam PF13280 WYL domain 143 325 1.1E-20 T 10-11-2016 IPR026881 WYL domain A4G23_RS12340 d7f2c8759bae1d531c28a05f7fff120a 255 Pfam PF13535 ATP-grasp domain 33 135 1.7E-13 T 10-11-2016 A4G23_RS12340 d7f2c8759bae1d531c28a05f7fff120a 255 SUPERFAMILY SSF56059 6 164 4.57E-24 T 10-11-2016 A4G23_RS12340 d7f2c8759bae1d531c28a05f7fff120a 255 Gene3D G3DSA:3.30.470.20 6 159 1.7E-13 T 10-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 A4G23_RS19830 a9df36c82ebc89054bff47aa453f25d5 719 PIRSF PIRSF000463 8 719 1.8E-289 T 10-11-2016 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 A4G23_RS19830 a9df36c82ebc89054bff47aa453f25d5 719 SMART SM00642 249 603 1.1E-8 T 10-11-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A4G23_RS19830 a9df36c82ebc89054bff47aa453f25d5 719 Pfam PF00128 Alpha amylase, catalytic domain 271 338 2.1E-11 T 10-11-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A4G23_RS19830 a9df36c82ebc89054bff47aa453f25d5 719 SUPERFAMILY SSF81296 18 114 1.75E-21 T 10-11-2016 IPR014756 Immunoglobulin E-set A4G23_RS19830 a9df36c82ebc89054bff47aa453f25d5 719 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 627 718 5.9E-14 T 10-11-2016 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 A4G23_RS19830 a9df36c82ebc89054bff47aa453f25d5 719 SUPERFAMILY SSF51445 170 615 1.58E-109 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS19830 a9df36c82ebc89054bff47aa453f25d5 719 Gene3D G3DSA:2.60.40.1180 622 718 6.7E-24 T 10-11-2016 IPR013780 Glycosyl hydrolase, all-beta A4G23_RS19830 a9df36c82ebc89054bff47aa453f25d5 719 Gene3D G3DSA:2.60.40.10 113 220 5.8E-34 T 10-11-2016 IPR013783 Immunoglobulin-like fold A4G23_RS19830 a9df36c82ebc89054bff47aa453f25d5 719 Gene3D G3DSA:2.60.40.10 15 105 1.3E-19 T 10-11-2016 IPR013783 Immunoglobulin-like fold A4G23_RS19830 a9df36c82ebc89054bff47aa453f25d5 719 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 100 719 42.722 T 10-11-2016 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 A4G23_RS19830 a9df36c82ebc89054bff47aa453f25d5 719 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 108 717 1.4E-289 T 10-11-2016 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 A4G23_RS19830 a9df36c82ebc89054bff47aa453f25d5 719 Gene3D G3DSA:3.20.20.80 245 609 1.6E-90 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS19830 a9df36c82ebc89054bff47aa453f25d5 719 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 124 206 1.4E-18 T 10-11-2016 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 A4G23_RS19830 a9df36c82ebc89054bff47aa453f25d5 719 SUPERFAMILY SSF51011 622 718 2.52E-22 T 10-11-2016 A4G23_RS14280 76591ef96543f15ac6bc134d5fc718d2 448 SMART SM01091 342 424 1.4E-17 T 10-11-2016 IPR005170 Transporter-associated domain A4G23_RS14280 76591ef96543f15ac6bc134d5fc718d2 448 Pfam PF01595 Domain of unknown function DUF21 10 189 4.1E-42 T 10-11-2016 IPR002550 Domain of unknown function DUF21 A4G23_RS14280 76591ef96543f15ac6bc134d5fc718d2 448 SUPERFAMILY SSF56176 341 422 4.91E-14 T 10-11-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 A4G23_RS14280 76591ef96543f15ac6bc134d5fc718d2 448 Pfam PF00571 CBS domain 278 327 1.5E-8 T 10-11-2016 IPR000644 CBS domain A4G23_RS14280 76591ef96543f15ac6bc134d5fc718d2 448 Pfam PF00571 CBS domain 215 266 0.0012 T 10-11-2016 IPR000644 CBS domain A4G23_RS14280 76591ef96543f15ac6bc134d5fc718d2 448 Gene3D G3DSA:3.30.465.10 337 423 4.9E-17 T 10-11-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 A4G23_RS14280 76591ef96543f15ac6bc134d5fc718d2 448 Pfam PF03471 Transporter associated domain 343 423 1.7E-14 T 10-11-2016 IPR005170 Transporter-associated domain A4G23_RS14280 76591ef96543f15ac6bc134d5fc718d2 448 SMART SM00116 279 327 0.31 T 10-11-2016 IPR000644 CBS domain A4G23_RS14280 76591ef96543f15ac6bc134d5fc718d2 448 SMART SM00116 219 269 2.8 T 10-11-2016 IPR000644 CBS domain A4G23_RS14280 76591ef96543f15ac6bc134d5fc718d2 448 Gene3D G3DSA:3.10.580.10 196 336 2.4E-20 T 10-11-2016 A4G23_RS14280 76591ef96543f15ac6bc134d5fc718d2 448 SUPERFAMILY SSF54631 207 344 9.47E-28 T 10-11-2016 A4G23_RS00875 8215965569ba5ef7af9b0f5f6ebf6767 330 Gene3D G3DSA:3.30.1180.20 185 329 3.3E-54 T 10-11-2016 A4G23_RS00875 8215965569ba5ef7af9b0f5f6ebf6767 330 TIGRFAM TIGR02363 dhaK1: dihydroxyacetone kinase, DhaK subunit 1 326 1.2E-141 T 10-11-2016 IPR012736 Dihydroxyacetone kinase DhaK, subunit 1 A4G23_RS00875 8215965569ba5ef7af9b0f5f6ebf6767 330 Pfam PF02733 Dak1 domain 17 325 8.3E-125 T 10-11-2016 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 A4G23_RS00875 8215965569ba5ef7af9b0f5f6ebf6767 330 Gene3D G3DSA:3.40.50.10440 11 182 1.8E-68 T 10-11-2016 A4G23_RS00875 8215965569ba5ef7af9b0f5f6ebf6767 330 SUPERFAMILY SSF82549 11 329 2.38E-116 T 10-11-2016 A4G23_RS27305 38a7e9beb18556c96e34efdeeaf80400 497 Gene3D G3DSA:3.40.50.980 3 179 1.5E-19 T 10-11-2016 A4G23_RS27305 38a7e9beb18556c96e34efdeeaf80400 497 Gene3D G3DSA:2.30.38.10 335 382 5.0E-4 T 10-11-2016 A4G23_RS27305 38a7e9beb18556c96e34efdeeaf80400 497 Gene3D G3DSA:3.30.300.30 384 479 1.5E-7 T 10-11-2016 A4G23_RS27305 38a7e9beb18556c96e34efdeeaf80400 497 Gene3D G3DSA:3.40.50.980 180 318 5.1E-10 T 10-11-2016 A4G23_RS27305 38a7e9beb18556c96e34efdeeaf80400 497 SUPERFAMILY SSF56801 2 484 3.66E-61 T 10-11-2016 A4G23_RS27305 38a7e9beb18556c96e34efdeeaf80400 497 Pfam PF00501 AMP-binding enzyme 7 388 3.9E-37 T 10-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A4G23_RS09995 bff1705f11f6b0dc96cbd980335e3e90 433 Gene3D G3DSA:3.90.1660.10 52 118 2.5E-23 T 10-11-2016 A4G23_RS09995 bff1705f11f6b0dc96cbd980335e3e90 433 Gene3D G3DSA:3.30.1330.100 119 209 9.0E-54 T 10-11-2016 A4G23_RS09995 bff1705f11f6b0dc96cbd980335e3e90 433 Gene3D G3DSA:3.30.1330.100 5 51 9.0E-54 T 10-11-2016 A4G23_RS09995 bff1705f11f6b0dc96cbd980335e3e90 433 Pfam PF01996 F420-0:Gamma-glutamyl ligase 82 204 1.3E-32 T 10-11-2016 IPR002847 Coenzyme F420:L-glutamate ligase-like domain KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 A4G23_RS09995 bff1705f11f6b0dc96cbd980335e3e90 433 Pfam PF01996 F420-0:Gamma-glutamyl ligase 13 68 1.5E-8 T 10-11-2016 IPR002847 Coenzyme F420:L-glutamate ligase-like domain KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 A4G23_RS09995 bff1705f11f6b0dc96cbd980335e3e90 433 Gene3D G3DSA:3.40.109.10 235 431 7.7E-41 T 10-11-2016 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4G23_RS09995 bff1705f11f6b0dc96cbd980335e3e90 433 Pfam PF00881 Nitroreductase family 245 413 2.5E-29 T 10-11-2016 IPR029479 Nitroreductase Reactome: R-HSA-209968 A4G23_RS09995 bff1705f11f6b0dc96cbd980335e3e90 433 SUPERFAMILY SSF55469 238 432 4.58E-39 T 10-11-2016 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4G23_RS09995 bff1705f11f6b0dc96cbd980335e3e90 433 SUPERFAMILY SSF144010 6 236 6.02E-65 T 10-11-2016 A4G23_RS09995 bff1705f11f6b0dc96cbd980335e3e90 433 TIGRFAM TIGR03553 F420_FbiB_CTERM: F420 biosynthesis protein FbiB, C-terminal domain 240 433 6.3E-98 T 10-11-2016 IPR019943 Coenzyme F420 biosynthesis protein FbiB, C-terminal GO:0016881 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 A4G23_RS09995 bff1705f11f6b0dc96cbd980335e3e90 433 Hamap MF_01259 Coenzyme F420:L-glutamate ligase [fbiB]. 10 433 51.743 T 10-11-2016 IPR023661 Coenzyme F420:L-glutamate ligase, bacteria GO:0043773|GO:0046872|GO:0051188 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 A4G23_RS09995 bff1705f11f6b0dc96cbd980335e3e90 433 TIGRFAM TIGR01916 F420_cofE: coenzyme F420-0:L-glutamate ligase 6 231 1.2E-74 T 10-11-2016 IPR008225 Coenzyme F420:L-glutamate ligase GO:0043773|GO:0046872|GO:0051188 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 A4G23_RS10475 c75b8d0055014643726fe877db7225e8 1176 SMART SM01058 498 599 3.9E-46 T 10-11-2016 IPR003711 CarD-like/TRCF domain A4G23_RS10475 c75b8d0055014643726fe877db7225e8 1176 SUPERFAMILY SSF52540 18 366 7.08E-70 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS10475 c75b8d0055014643726fe877db7225e8 1176 Pfam PF00270 DEAD/DEAH box helicase 629 790 4.5E-16 T 10-11-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A4G23_RS10475 c75b8d0055014643726fe877db7225e8 1176 SUPERFAMILY SSF52540 548 806 1.09E-60 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS10475 c75b8d0055014643726fe877db7225e8 1176 SUPERFAMILY SSF141259 491 571 9.81E-18 T 10-11-2016 IPR003711 CarD-like/TRCF domain A4G23_RS10475 c75b8d0055014643726fe877db7225e8 1176 Gene3D G3DSA:3.40.50.300 611 809 1.1E-52 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS10475 c75b8d0055014643726fe877db7225e8 1176 Pfam PF02559 CarD-like/TRCF domain 499 598 3.0E-30 T 10-11-2016 IPR003711 CarD-like/TRCF domain A4G23_RS10475 c75b8d0055014643726fe877db7225e8 1176 SUPERFAMILY SSF52540 386 481 2.87E-12 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS10475 c75b8d0055014643726fe877db7225e8 1176 SUPERFAMILY SSF52540 805 1013 2.45E-45 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS10475 c75b8d0055014643726fe877db7225e8 1176 SUPERFAMILY SSF143517 1018 1138 3.53E-32 T 10-11-2016 A4G23_RS10475 c75b8d0055014643726fe877db7225e8 1176 Gene3D G3DSA:3.40.50.300 826 979 1.0E-32 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS10475 c75b8d0055014643726fe877db7225e8 1176 Pfam PF03461 TRCF domain 1032 1114 6.3E-24 T 10-11-2016 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 A4G23_RS10475 c75b8d0055014643726fe877db7225e8 1176 Gene3D G3DSA:3.30.2060.10 149 224 8.5E-15 T 10-11-2016 A4G23_RS10475 c75b8d0055014643726fe877db7225e8 1176 Pfam PF00271 Helicase conserved C-terminal domain 833 932 8.0E-15 T 10-11-2016 IPR001650 Helicase, C-terminal A4G23_RS10475 c75b8d0055014643726fe877db7225e8 1176 SMART SM00487 623 813 1.8E-30 T 10-11-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4G23_RS10475 c75b8d0055014643726fe877db7225e8 1176 SMART SM00982 1031 1129 3.0E-36 T 10-11-2016 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 A4G23_RS10475 c75b8d0055014643726fe877db7225e8 1176 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 167 1103 0.0 T 10-11-2016 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 A4G23_RS10475 c75b8d0055014643726fe877db7225e8 1176 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 44 1124 28.644 T 10-11-2016 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 A4G23_RS10475 c75b8d0055014643726fe877db7225e8 1176 SMART SM00490 849 933 7.4E-16 T 10-11-2016 IPR001650 Helicase, C-terminal A4G23_RS00690 d8443769a8d432f205bffeb93773ef85 750 Pfam PF14498 Glycosyl hydrolase family 65, N-terminal domain 5 168 3.5E-18 T 10-11-2016 IPR027414 Glycosyl hydrolase family, N-terminal domain KEGG: 00511+3.2.1.51 A4G23_RS00690 d8443769a8d432f205bffeb93773ef85 750 PIRSF PIRSF007663 1 748 1.9E-145 T 10-11-2016 IPR016518 Alpha-L-fucosidase GO:0004560 KEGG: 00511+3.2.1.51 A4G23_RS00690 d8443769a8d432f205bffeb93773ef85 750 SUPERFAMILY SSF48208 275 726 1.7E-43 T 10-11-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 A4G23_RS00690 d8443769a8d432f205bffeb93773ef85 750 Gene3D G3DSA:2.70.98.50 5 385 7.0E-56 T 10-11-2016 IPR027414 Glycosyl hydrolase family, N-terminal domain KEGG: 00511+3.2.1.51 A4G23_RS27025 e1a6d6437aa3da519c22527a49fa3060 198 Pfam PF01872 RibD C-terminal domain 5 188 4.4E-29 T 10-11-2016 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 A4G23_RS27025 e1a6d6437aa3da519c22527a49fa3060 198 Gene3D G3DSA:3.40.430.10 2 194 4.4E-29 T 10-11-2016 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 A4G23_RS27025 e1a6d6437aa3da519c22527a49fa3060 198 SUPERFAMILY SSF53597 5 195 9.42E-31 T 10-11-2016 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 A4G23_RS27215 f5c6709fe5bb2931e4e35d7bb30e2c9f 428 Gene3D G3DSA:2.30.38.10 151 227 7.9E-23 T 10-11-2016 A4G23_RS27215 f5c6709fe5bb2931e4e35d7bb30e2c9f 428 Gene3D G3DSA:3.40.50.980 16 150 1.0E-33 T 10-11-2016 A4G23_RS27215 f5c6709fe5bb2931e4e35d7bb30e2c9f 428 SMART SM00823 Phosphopantetheine attachment site 356 425 8.7E-10 T 10-11-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4G23_RS27215 f5c6709fe5bb2931e4e35d7bb30e2c9f 428 SUPERFAMILY SSF56801 3 368 1.18E-89 T 10-11-2016 A4G23_RS27215 f5c6709fe5bb2931e4e35d7bb30e2c9f 428 Pfam PF00550 Phosphopantetheine attachment site 358 421 5.4E-16 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS27215 f5c6709fe5bb2931e4e35d7bb30e2c9f 428 ProSitePatterns PS00012 Phosphopantetheine attachment site. 380 395 - T 10-11-2016 IPR006162 Phosphopantetheine attachment site A4G23_RS27215 f5c6709fe5bb2931e4e35d7bb30e2c9f 428 SUPERFAMILY SSF47336 348 421 4.06E-19 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS27215 f5c6709fe5bb2931e4e35d7bb30e2c9f 428 Pfam PF13193 AMP-binding enzyme C-terminal domain 246 327 1.1E-10 T 10-11-2016 IPR025110 AMP-binding enzyme C-terminal domain A4G23_RS27215 f5c6709fe5bb2931e4e35d7bb30e2c9f 428 Gene3D G3DSA:1.10.1200.10 360 424 1.8E-25 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS27215 f5c6709fe5bb2931e4e35d7bb30e2c9f 428 Pfam PF00501 AMP-binding enzyme 3 238 4.0E-47 T 10-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A4G23_RS27215 f5c6709fe5bb2931e4e35d7bb30e2c9f 428 Gene3D G3DSA:3.30.300.30 233 359 1.2E-32 T 10-11-2016 A4G23_RS02480 b155679f478002384e1e15e8a93ca70d 181 SUPERFAMILY SSF56420 13 170 4.19E-54 T 10-11-2016 IPR023635 Peptide deformylase A4G23_RS02480 b155679f478002384e1e15e8a93ca70d 181 PRINTS PR01576 Peptide deformylase signature 102 113 1.2E-32 T 10-11-2016 IPR023635 Peptide deformylase A4G23_RS02480 b155679f478002384e1e15e8a93ca70d 181 PRINTS PR01576 Peptide deformylase signature 133 162 1.2E-32 T 10-11-2016 IPR023635 Peptide deformylase A4G23_RS02480 b155679f478002384e1e15e8a93ca70d 181 PRINTS PR01576 Peptide deformylase signature 43 72 1.2E-32 T 10-11-2016 IPR023635 Peptide deformylase A4G23_RS02480 b155679f478002384e1e15e8a93ca70d 181 PRINTS PR01576 Peptide deformylase signature 114 132 1.2E-32 T 10-11-2016 IPR023635 Peptide deformylase A4G23_RS02480 b155679f478002384e1e15e8a93ca70d 181 Gene3D G3DSA:3.90.45.10 17 177 9.4E-57 T 10-11-2016 IPR023635 Peptide deformylase A4G23_RS02480 b155679f478002384e1e15e8a93ca70d 181 Hamap MF_00163 Peptide deformylase [def]. 12 175 27.546 T 10-11-2016 IPR023635 Peptide deformylase A4G23_RS02480 b155679f478002384e1e15e8a93ca70d 181 PIRSF PIRSF004749 2 176 9.5E-41 T 10-11-2016 IPR023635 Peptide deformylase A4G23_RS02480 b155679f478002384e1e15e8a93ca70d 181 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 19 166 2.8E-37 T 10-11-2016 IPR023635 Peptide deformylase A4G23_RS02480 b155679f478002384e1e15e8a93ca70d 181 Pfam PF01327 Polypeptide deformylase 16 162 7.2E-42 T 10-11-2016 IPR023635 Peptide deformylase A4G23_RS13020 2aad733051566c0ca6ed42d27dd93cd3 404 Gene3D G3DSA:3.30.950.10 104 205 7.0E-27 T 10-11-2016 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A4G23_RS13020 2aad733051566c0ca6ed42d27dd93cd3 404 PIRSF PIRSF036428 1 400 4.6E-143 T 10-11-2016 IPR006365 Cobalamin (vitamin B12) biosynthesis CobL/Precorrin-6Y C(5,15)-methyltransferase GO:0008276|GO:0009236 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|KEGG: 00860+2.1.1.132|MetaCyc: PWY-2201|MetaCyc: PWY-3841 A4G23_RS13020 2aad733051566c0ca6ed42d27dd93cd3 404 SUPERFAMILY SSF53790 1 202 5.23E-38 T 10-11-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A4G23_RS13020 2aad733051566c0ca6ed42d27dd93cd3 404 TIGRFAM TIGR02469 CbiT: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit 228 350 1.9E-32 T 10-11-2016 IPR014008 Cobalamin biosynthesis, precorrin-6Y methyltransferase, CbiT subunit GO:0008276|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.196|MetaCyc: PWY-2201|MetaCyc: PWY-7377 A4G23_RS13020 2aad733051566c0ca6ed42d27dd93cd3 404 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 231 368 1.2E-4 T 10-11-2016 A4G23_RS13020 2aad733051566c0ca6ed42d27dd93cd3 404 SUPERFAMILY SSF53335 205 394 1.28E-30 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS13020 2aad733051566c0ca6ed42d27dd93cd3 404 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 1 191 3.4E-45 T 10-11-2016 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 A4G23_RS13020 2aad733051566c0ca6ed42d27dd93cd3 404 Gene3D G3DSA:3.40.50.150 219 390 9.0E-22 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS13020 2aad733051566c0ca6ed42d27dd93cd3 404 Gene3D G3DSA:3.40.1010.10 1 103 1.8E-23 T 10-11-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A4G23_RS13020 2aad733051566c0ca6ed42d27dd93cd3 404 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 1 186 1.7E-21 T 10-11-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A4G23_RS14490 af9226d03bba5ed61c00bbad5f5acd69 573 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 211 530 15.308 T 10-11-2016 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 A4G23_RS14490 af9226d03bba5ed61c00bbad5f5acd69 573 Gene3D G3DSA:3.40.50.150 298 465 3.0E-41 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS14490 af9226d03bba5ed61c00bbad5f5acd69 573 SUPERFAMILY SSF103473 30 216 1.09E-7 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS14490 af9226d03bba5ed61c00bbad5f5acd69 573 Pfam PF01564 Spermine/spermidine synthase 287 464 6.7E-17 T 10-11-2016 A4G23_RS14490 af9226d03bba5ed61c00bbad5f5acd69 573 SUPERFAMILY SSF53335 240 465 5.73E-36 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS14490 af9226d03bba5ed61c00bbad5f5acd69 573 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 315 328 - T 10-11-2016 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 A4G23_RS24815 6975338b15c10f038db08dde556f75d6 823 Pfam PF16921 Tex protein YqgF-like domain 324 449 1.1E-49 T 10-11-2016 IPR032639 Tex protein, YqgF-like domain A4G23_RS24815 6975338b15c10f038db08dde556f75d6 823 Gene3D G3DSA:1.10.150.310 497 628 3.5E-46 T 10-11-2016 IPR023097 Tex RuvX-like domain A4G23_RS24815 6975338b15c10f038db08dde556f75d6 823 SUPERFAMILY SSF47781 558 629 2.22E-19 T 10-11-2016 IPR010994 RuvA domain 2-like A4G23_RS24815 6975338b15c10f038db08dde556f75d6 823 SUPERFAMILY SSF53098 319 467 2.43E-49 T 10-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 A4G23_RS24815 6975338b15c10f038db08dde556f75d6 823 SMART SM00316 647 718 3.3E-26 T 10-11-2016 IPR022967 RNA-binding domain, S1 A4G23_RS24815 6975338b15c10f038db08dde556f75d6 823 Gene3D G3DSA:3.30.420.140 323 448 1.3E-48 T 10-11-2016 IPR006641 YqgF/RNase H-like domain GO:0006139 A4G23_RS24815 6975338b15c10f038db08dde556f75d6 823 Pfam PF00575 S1 RNA binding domain 647 718 2.3E-21 T 10-11-2016 IPR003029 S1 domain GO:0003676 A4G23_RS24815 6975338b15c10f038db08dde556f75d6 823 SUPERFAMILY SSF47781 468 556 1.01E-27 T 10-11-2016 IPR010994 RuvA domain 2-like A4G23_RS24815 6975338b15c10f038db08dde556f75d6 823 Gene3D G3DSA:1.10.3500.10 449 496 1.1E-99 T 10-11-2016 IPR023323 Tex-like domain A4G23_RS24815 6975338b15c10f038db08dde556f75d6 823 Gene3D G3DSA:1.10.3500.10 110 319 1.1E-99 T 10-11-2016 IPR023323 Tex-like domain A4G23_RS24815 6975338b15c10f038db08dde556f75d6 823 Gene3D G3DSA:2.40.50.140 637 718 4.3E-26 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS24815 6975338b15c10f038db08dde556f75d6 823 SMART SM00732 323 422 8.9E-38 T 10-11-2016 IPR006641 YqgF/RNase H-like domain GO:0006139 A4G23_RS24815 6975338b15c10f038db08dde556f75d6 823 Pfam PF09371 Tex-like protein N-terminal domain 9 192 1.7E-67 T 10-11-2016 IPR018974 Tex-like protein, N-terminal A4G23_RS24815 6975338b15c10f038db08dde556f75d6 823 SUPERFAMILY SSF50249 636 721 4.62E-24 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS24815 6975338b15c10f038db08dde556f75d6 823 Gene3D G3DSA:1.10.10.650 3 109 1.3E-44 T 10-11-2016 IPR023319 Tex-like protein, HTH domain A4G23_RS24815 6975338b15c10f038db08dde556f75d6 823 Pfam PF12836 Helix-hairpin-helix motif 489 553 5.4E-29 T 10-11-2016 A4G23_RS24815 6975338b15c10f038db08dde556f75d6 823 SUPERFAMILY SSF158832 3 318 1.96E-114 T 10-11-2016 A4G23_RS07690 53142a8bfc1b2378a92189dd459cbf3e 425 Gene3D G3DSA:3.30.390.30 333 421 1.1E-26 T 10-11-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A4G23_RS07690 53142a8bfc1b2378a92189dd459cbf3e 425 SUPERFAMILY SSF51905 7 199 2.43E-44 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS07690 53142a8bfc1b2378a92189dd459cbf3e 425 Pfam PF14759 Reductase C-terminal 333 421 1.8E-14 T 10-11-2016 IPR028202 Reductase, C-terminal A4G23_RS07690 53142a8bfc1b2378a92189dd459cbf3e 425 SUPERFAMILY SSF51905 153 323 4.29E-32 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS07690 53142a8bfc1b2378a92189dd459cbf3e 425 SUPERFAMILY SSF55424 326 422 1.65E-23 T 10-11-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 A4G23_RS07690 53142a8bfc1b2378a92189dd459cbf3e 425 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 239 255 1.4E-25 T 10-11-2016 A4G23_RS07690 53142a8bfc1b2378a92189dd459cbf3e 425 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 104 122 1.4E-25 T 10-11-2016 A4G23_RS07690 53142a8bfc1b2378a92189dd459cbf3e 425 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 1.4E-25 T 10-11-2016 A4G23_RS07690 53142a8bfc1b2378a92189dd459cbf3e 425 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 153 171 1.4E-25 T 10-11-2016 A4G23_RS07690 53142a8bfc1b2378a92189dd459cbf3e 425 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 269 291 1.4E-25 T 10-11-2016 A4G23_RS07690 53142a8bfc1b2378a92189dd459cbf3e 425 Gene3D G3DSA:3.50.50.60 5 112 5.8E-34 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS07690 53142a8bfc1b2378a92189dd459cbf3e 425 Gene3D G3DSA:3.50.50.60 113 323 9.5E-53 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS07690 53142a8bfc1b2378a92189dd459cbf3e 425 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 313 5.6E-63 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS07690 53142a8bfc1b2378a92189dd459cbf3e 425 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 240 254 9.4E-16 T 10-11-2016 A4G23_RS07690 53142a8bfc1b2378a92189dd459cbf3e 425 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 9.4E-16 T 10-11-2016 A4G23_RS07690 53142a8bfc1b2378a92189dd459cbf3e 425 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 153 178 9.4E-16 T 10-11-2016 A4G23_RS07690 53142a8bfc1b2378a92189dd459cbf3e 425 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 284 291 9.4E-16 T 10-11-2016 A4G23_RS24275 562cf323425ffe08e4d1e98fa51d6bbd 174 SUPERFAMILY SSF54637 2 148 3.3E-43 T 10-11-2016 IPR029069 HotDog domain A4G23_RS24275 562cf323425ffe08e4d1e98fa51d6bbd 174 Pfam PF01575 MaoC like domain 12 115 2.3E-15 T 10-11-2016 IPR002539 MaoC-like domain A4G23_RS24275 562cf323425ffe08e4d1e98fa51d6bbd 174 Gene3D G3DSA:3.10.129.10 2 148 5.0E-43 T 10-11-2016 IPR029069 HotDog domain A4G23_RS17145 01bb35d534062cc25628cea90b88445e 387 SMART SM00327 214 373 0.0042 T 10-11-2016 IPR002035 von Willebrand factor, type A A4G23_RS17145 01bb35d534062cc25628cea90b88445e 387 SUPERFAMILY SSF53300 212 376 5.72E-24 T 10-11-2016 IPR002035 von Willebrand factor, type A A4G23_RS17145 01bb35d534062cc25628cea90b88445e 387 Pfam PF05762 VWA domain containing CoxE-like protein 152 371 4.8E-61 T 10-11-2016 IPR008912 Uncharacterised protein family CoxE-like A4G23_RS17145 01bb35d534062cc25628cea90b88445e 387 Gene3D G3DSA:3.40.50.410 213 334 7.7E-5 T 10-11-2016 IPR002035 von Willebrand factor, type A A4G23_RS05960 a6cfe1461dc273d2f06c7f527e44e32b 1520 Gene3D G3DSA:3.60.20.10 28 447 2.4E-186 T 10-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal A4G23_RS05960 a6cfe1461dc273d2f06c7f527e44e32b 1520 Gene3D G3DSA:2.160.20.60 1233 1508 3.2E-104 T 10-11-2016 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 A4G23_RS05960 a6cfe1461dc273d2f06c7f527e44e32b 1520 Pfam PF00310 Glutamine amidotransferases class-II 28 436 6.1E-180 T 10-11-2016 IPR017932 Glutamine amidotransferase type 2 domain A4G23_RS05960 a6cfe1461dc273d2f06c7f527e44e32b 1520 Gene3D G3DSA:3.20.20.70 850 1211 8.5E-181 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS05960 a6cfe1461dc273d2f06c7f527e44e32b 1520 SUPERFAMILY SSF69336 1228 1493 1.26E-87 T 10-11-2016 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 A4G23_RS05960 a6cfe1461dc273d2f06c7f527e44e32b 1520 SUPERFAMILY SSF56235 28 438 9.01E-151 T 10-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal A4G23_RS05960 a6cfe1461dc273d2f06c7f527e44e32b 1520 SUPERFAMILY SSF51395 451 1215 1.51E-265 T 10-11-2016 A4G23_RS05960 a6cfe1461dc273d2f06c7f527e44e32b 1520 Pfam PF01645 Conserved region in glutamate synthase 816 1179 2.2E-157 T 10-11-2016 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 A4G23_RS05960 a6cfe1461dc273d2f06c7f527e44e32b 1520 Pfam PF01493 GXGXG motif 1264 1440 7.0E-76 T 10-11-2016 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 A4G23_RS05960 a6cfe1461dc273d2f06c7f527e44e32b 1520 Gene3D G3DSA:3.20.20.70 448 803 6.0E-104 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS05960 a6cfe1461dc273d2f06c7f527e44e32b 1520 Pfam PF04898 Glutamate synthase central domain 463 751 3.6E-113 T 10-11-2016 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 A4G23_RS20485 787ccb69fbf7830ec90b97ca7e2100e3 516 Gene3D G3DSA:1.20.120.140 2 89 3.4E-35 T 10-11-2016 A4G23_RS20485 787ccb69fbf7830ec90b97ca7e2100e3 516 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 449 33.017 T 10-11-2016 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 A4G23_RS20485 787ccb69fbf7830ec90b97ca7e2100e3 516 SMART SM00382 99 303 6.2E-11 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS20485 787ccb69fbf7830ec90b97ca7e2100e3 516 Gene3D G3DSA:1.10.260.30 333 434 2.7E-37 T 10-11-2016 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A4G23_RS20485 787ccb69fbf7830ec90b97ca7e2100e3 516 Pfam PF00448 SRP54-type protein, GTPase domain 100 298 7.1E-67 T 10-11-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A4G23_RS20485 787ccb69fbf7830ec90b97ca7e2100e3 516 Gene3D G3DSA:3.40.50.300 94 299 3.5E-72 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS20485 787ccb69fbf7830ec90b97ca7e2100e3 516 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 431 4.7E-173 T 10-11-2016 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 A4G23_RS20485 787ccb69fbf7830ec90b97ca7e2100e3 516 Pfam PF02978 Signal peptide binding domain 333 430 5.3E-31 T 10-11-2016 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A4G23_RS20485 787ccb69fbf7830ec90b97ca7e2100e3 516 SMART SM00963 1 86 1.1E-34 T 10-11-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A4G23_RS20485 787ccb69fbf7830ec90b97ca7e2100e3 516 SUPERFAMILY SSF47446 300 433 1.44E-42 T 10-11-2016 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A4G23_RS20485 787ccb69fbf7830ec90b97ca7e2100e3 516 SUPERFAMILY SSF52540 42 359 6.54E-58 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS20485 787ccb69fbf7830ec90b97ca7e2100e3 516 SMART SM00962 100 298 8.6E-106 T 10-11-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A4G23_RS20485 787ccb69fbf7830ec90b97ca7e2100e3 516 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 8.3E-21 T 10-11-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A4G23_RS08430 d9bfb5bc1f23fa206b828a49e55df9d2 854 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 178 193 6.1E-23 T 10-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4G23_RS08430 d9bfb5bc1f23fa206b828a49e55df9d2 854 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 262 272 6.1E-23 T 10-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4G23_RS08430 d9bfb5bc1f23fa206b828a49e55df9d2 854 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 296 311 6.1E-23 T 10-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4G23_RS08430 d9bfb5bc1f23fa206b828a49e55df9d2 854 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 315 327 6.1E-23 T 10-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4G23_RS08430 d9bfb5bc1f23fa206b828a49e55df9d2 854 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 135 150 6.1E-23 T 10-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4G23_RS08430 d9bfb5bc1f23fa206b828a49e55df9d2 854 SUPERFAMILY SSF55486 211 456 1.08E-74 T 10-11-2016 A4G23_RS08430 d9bfb5bc1f23fa206b828a49e55df9d2 854 Gene3D G3DSA:1.10.390.10 309 456 4.3E-42 T 10-11-2016 A4G23_RS08430 d9bfb5bc1f23fa206b828a49e55df9d2 854 Pfam PF01433 Peptidase family M1 22 390 2.6E-73 T 10-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4G23_RS08430 d9bfb5bc1f23fa206b828a49e55df9d2 854 TIGRFAM TIGR02412 pepN_strep_liv: aminopeptidase N 5 851 0.0 T 10-11-2016 IPR012778 Peptidase M1, aminopeptidase GO:0004177|GO:0006508 KEGG: 00480+3.4.11.2|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112 A4G23_RS08430 d9bfb5bc1f23fa206b828a49e55df9d2 854 Pfam PF11838 ERAP1-like C-terminal domain 536 845 8.6E-60 T 10-11-2016 IPR024571 ERAP1-like C-terminal domain A4G23_RS08430 d9bfb5bc1f23fa206b828a49e55df9d2 854 SUPERFAMILY SSF63737 5 195 4.84E-38 T 10-11-2016 A4G23_RS22600 5674954600595e94836732c2e19206f8 355 SUPERFAMILY SSF50494 125 337 2.52E-25 T 10-11-2016 IPR009003 Peptidase S1, PA clan A4G23_RS22600 5674954600595e94836732c2e19206f8 355 Pfam PF13365 Trypsin-like peptidase domain 148 323 2.7E-20 T 10-11-2016 A4G23_RS22600 5674954600595e94836732c2e19206f8 355 Gene3D G3DSA:2.40.10.10 234 335 1.5E-13 T 10-11-2016 A4G23_RS22600 5674954600595e94836732c2e19206f8 355 Gene3D G3DSA:2.40.10.10 143 232 1.3E-14 T 10-11-2016 A4G23_RS02380 eda9d1614555b42352c7e67bd143acb9 647 Gene3D G3DSA:3.40.50.300 358 590 3.0E-79 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS02380 eda9d1614555b42352c7e67bd143acb9 647 SMART SM00382 386 572 7.4E-13 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS02380 eda9d1614555b42352c7e67bd143acb9 647 Gene3D G3DSA:1.20.1560.10 24 344 2.8E-67 T 10-11-2016 A4G23_RS02380 eda9d1614555b42352c7e67bd143acb9 647 Pfam PF00005 ABC transporter 377 526 1.3E-28 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS02380 eda9d1614555b42352c7e67bd143acb9 647 SUPERFAMILY SSF90123 24 341 1.96E-67 T 10-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A4G23_RS02380 eda9d1614555b42352c7e67bd143acb9 647 ProSitePatterns PS00211 ABC transporters family signature. 498 512 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS02380 eda9d1614555b42352c7e67bd143acb9 647 SUPERFAMILY SSF52540 348 594 1.33E-89 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS02380 eda9d1614555b42352c7e67bd143acb9 647 Pfam PF00664 ABC transporter transmembrane region 39 311 1.7E-34 T 10-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A4G23_RS02220 a5109763b1960c8c6998a5991220bf5e 523 SUPERFAMILY SSF52540 252 484 1.81E-43 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS02220 a5109763b1960c8c6998a5991220bf5e 523 Pfam PF00005 ABC transporter 278 433 1.9E-17 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS02220 a5109763b1960c8c6998a5991220bf5e 523 Pfam PF00005 ABC transporter 14 165 1.6E-28 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS02220 a5109763b1960c8c6998a5991220bf5e 523 Gene3D G3DSA:3.40.50.300 255 486 6.5E-47 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS02220 a5109763b1960c8c6998a5991220bf5e 523 SUPERFAMILY SSF52540 2 222 2.83E-55 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS02220 a5109763b1960c8c6998a5991220bf5e 523 Gene3D G3DSA:3.40.50.300 2 221 4.1E-60 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS02220 a5109763b1960c8c6998a5991220bf5e 523 ProSitePatterns PS00211 ABC transporters family signature. 406 420 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS02220 a5109763b1960c8c6998a5991220bf5e 523 SMART SM00382 286 489 6.7E-4 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS02220 a5109763b1960c8c6998a5991220bf5e 523 SMART SM00382 23 213 2.3E-11 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS12355 7765908c8cf663a632738821ee3f2cd5 201 SUPERFAMILY SSF46689 2 81 5.99E-18 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS12355 7765908c8cf663a632738821ee3f2cd5 201 ProSitePatterns PS01081 TetR-type HTH domain signature. 25 56 - T 10-11-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A4G23_RS12355 7765908c8cf663a632738821ee3f2cd5 201 Gene3D G3DSA:1.10.357.10 55 184 2.2E-16 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS12355 7765908c8cf663a632738821ee3f2cd5 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 56 1.7E-17 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS12355 7765908c8cf663a632738821ee3f2cd5 201 Gene3D G3DSA:1.10.10.60 2 54 4.7E-20 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS12355 7765908c8cf663a632738821ee3f2cd5 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 2.0E-9 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS12355 7765908c8cf663a632738821ee3f2cd5 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 2.0E-9 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS01185 cfdb2afd59ff654d2ef0990deb799984 252 Pfam PF13649 Methyltransferase domain 61 156 5.1E-19 T 10-11-2016 A4G23_RS01185 cfdb2afd59ff654d2ef0990deb799984 252 Gene3D G3DSA:3.40.50.150 21 216 4.8E-32 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS01185 cfdb2afd59ff654d2ef0990deb799984 252 SUPERFAMILY SSF53335 20 220 1.02E-32 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS01280 6a2816aa379c78c19fc3a2a16d3f90fd 479 SUPERFAMILY SSF48264 31 426 9.3E-60 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS01280 6a2816aa379c78c19fc3a2a16d3f90fd 479 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 366 375 - T 10-11-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A4G23_RS01280 6a2816aa379c78c19fc3a2a16d3f90fd 479 Gene3D G3DSA:1.10.630.10 34 426 1.3E-89 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS01280 6a2816aa379c78c19fc3a2a16d3f90fd 479 PRINTS PR00359 B-class P450 signature 187 202 2.5E-22 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS01280 6a2816aa379c78c19fc3a2a16d3f90fd 479 PRINTS PR00359 B-class P450 signature 317 344 2.5E-22 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS01280 6a2816aa379c78c19fc3a2a16d3f90fd 479 PRINTS PR00359 B-class P450 signature 364 373 2.5E-22 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS01280 6a2816aa379c78c19fc3a2a16d3f90fd 479 PRINTS PR00359 B-class P450 signature 221 243 2.5E-22 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS01280 6a2816aa379c78c19fc3a2a16d3f90fd 479 PRINTS PR00359 B-class P450 signature 124 135 2.5E-22 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS01280 6a2816aa379c78c19fc3a2a16d3f90fd 479 PRINTS PR00359 B-class P450 signature 170 186 2.5E-22 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS25860 74c7531ed137bdc074d322fa0206ff3d 76 SUPERFAMILY SSF89807 3 68 7.06E-26 T 10-11-2016 IPR009923 Dodecin A4G23_RS25860 74c7531ed137bdc074d322fa0206ff3d 76 Pfam PF07311 Dodecin 5 68 1.5E-29 T 10-11-2016 IPR009923 Dodecin A4G23_RS25860 74c7531ed137bdc074d322fa0206ff3d 76 Gene3D G3DSA:3.30.1660.10 2 69 1.1E-36 T 10-11-2016 IPR025543 Dodecin-like A4G23_RS11570 af8bf8a60abecfc304201da48f9fcc0c 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 71 4.4E-13 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS11570 af8bf8a60abecfc304201da48f9fcc0c 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 1.4E-8 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS11570 af8bf8a60abecfc304201da48f9fcc0c 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 1.4E-8 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS11570 af8bf8a60abecfc304201da48f9fcc0c 198 Gene3D G3DSA:1.10.357.10 12 197 1.2E-28 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS11570 af8bf8a60abecfc304201da48f9fcc0c 198 SUPERFAMILY SSF46689 12 86 3.95E-18 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS02990 81659649bbd6a86080886c2f949b7afd 446 SUPERFAMILY SSF46785 12 83 2.31E-14 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS02990 81659649bbd6a86080886c2f949b7afd 446 Gene3D G3DSA:3.40.640.10 127 329 3.5E-34 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS02990 81659649bbd6a86080886c2f949b7afd 446 Gene3D G3DSA:3.90.1150.10 330 416 5.7E-6 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS02990 81659649bbd6a86080886c2f949b7afd 446 Pfam PF00155 Aminotransferase class I and II 133 431 2.3E-18 T 10-11-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4G23_RS02990 81659649bbd6a86080886c2f949b7afd 446 SUPERFAMILY SSF53383 70 435 7.51E-59 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS02990 81659649bbd6a86080886c2f949b7afd 446 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 74 2.7E-13 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS02990 81659649bbd6a86080886c2f949b7afd 446 Gene3D G3DSA:1.10.10.10 14 84 4.9E-18 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS02990 81659649bbd6a86080886c2f949b7afd 446 SMART SM00345 15 74 1.8E-13 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS24025 c8c068628c66a62965a0ad876dcd9227 304 Pfam PF00106 short chain dehydrogenase 15 202 3.1E-44 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS24025 c8c068628c66a62965a0ad876dcd9227 304 Gene3D G3DSA:3.40.50.720 16 272 7.9E-66 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS24025 c8c068628c66a62965a0ad876dcd9227 304 SUPERFAMILY SSF51735 16 271 9.65E-61 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS24025 c8c068628c66a62965a0ad876dcd9227 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 8.4E-24 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS24025 c8c068628c66a62965a0ad876dcd9227 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 8.4E-24 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS24025 c8c068628c66a62965a0ad876dcd9227 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 8.4E-24 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS24025 c8c068628c66a62965a0ad876dcd9227 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 8.4E-24 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS24025 c8c068628c66a62965a0ad876dcd9227 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 8.4E-24 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS24025 c8c068628c66a62965a0ad876dcd9227 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 234 254 8.4E-24 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS24025 c8c068628c66a62965a0ad876dcd9227 304 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 1.1E-5 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS24025 c8c068628c66a62965a0ad876dcd9227 304 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 1.1E-5 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS24025 c8c068628c66a62965a0ad876dcd9227 304 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 1.1E-5 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS11335 95497289d1bcb7f04eb07647804edd03 105 SUPERFAMILY SSF51182 20 103 3.72E-9 T 10-11-2016 IPR011051 RmlC-like cupin domain A4G23_RS11335 95497289d1bcb7f04eb07647804edd03 105 Gene3D G3DSA:2.60.120.10 17 102 2.4E-12 T 10-11-2016 IPR014710 RmlC-like jelly roll fold A4G23_RS13515 047b0da0c6c6364a7b0dee0d32b59e3b 114 Pfam PF00085 Thioredoxin 5 103 2.0E-33 T 10-11-2016 IPR013766 Thioredoxin domain GO:0045454 A4G23_RS13515 047b0da0c6c6364a7b0dee0d32b59e3b 114 ProSitePatterns PS00194 Thioredoxin family active site. 24 42 - T 10-11-2016 IPR017937 Thioredoxin, conserved site GO:0045454 A4G23_RS13515 047b0da0c6c6364a7b0dee0d32b59e3b 114 PRINTS PR00421 Thioredoxin family signature 71 82 9.8E-8 T 10-11-2016 A4G23_RS13515 047b0da0c6c6364a7b0dee0d32b59e3b 114 PRINTS PR00421 Thioredoxin family signature 23 31 9.8E-8 T 10-11-2016 A4G23_RS13515 047b0da0c6c6364a7b0dee0d32b59e3b 114 PRINTS PR00421 Thioredoxin family signature 31 40 9.8E-8 T 10-11-2016 A4G23_RS13515 047b0da0c6c6364a7b0dee0d32b59e3b 114 TIGRFAM TIGR01068 thioredoxin: thioredoxin 8 105 1.4E-37 T 10-11-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 A4G23_RS13515 047b0da0c6c6364a7b0dee0d32b59e3b 114 PIRSF PIRSF000077 2 107 1.5E-43 T 10-11-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 A4G23_RS13515 047b0da0c6c6364a7b0dee0d32b59e3b 114 Gene3D G3DSA:3.40.30.10 4 106 3.6E-37 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS13515 047b0da0c6c6364a7b0dee0d32b59e3b 114 SUPERFAMILY SSF52833 3 108 4.93E-37 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS06560 0e0fbfd32591c745035b49c71969fb94 414 Pfam PF03734 L,D-transpeptidase catalytic domain 245 366 2.0E-14 T 10-11-2016 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 A4G23_RS06560 0e0fbfd32591c745035b49c71969fb94 414 SUPERFAMILY SSF141523 240 366 1.31E-29 T 10-11-2016 A4G23_RS06560 0e0fbfd32591c745035b49c71969fb94 414 Gene3D G3DSA:2.40.440.10 245 368 6.1E-19 T 10-11-2016 A4G23_RS18175 754aba48a18fdd513f2ba4a4c3c58078 440 Pfam PF02562 PhoH-like protein 230 435 4.9E-54 T 10-11-2016 IPR003714 PhoH-like protein GO:0005524 A4G23_RS18175 754aba48a18fdd513f2ba4a4c3c58078 440 SUPERFAMILY SSF88723 105 151 7.85E-9 T 10-11-2016 IPR029060 PIN domain-like A4G23_RS18175 754aba48a18fdd513f2ba4a4c3c58078 440 SUPERFAMILY SSF88723 14 72 7.85E-9 T 10-11-2016 IPR029060 PIN domain-like A4G23_RS18175 754aba48a18fdd513f2ba4a4c3c58078 440 Gene3D G3DSA:3.40.50.300 229 435 1.6E-52 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS18175 754aba48a18fdd513f2ba4a4c3c58078 440 Gene3D G3DSA:3.40.50.1010 105 153 5.5E-10 T 10-11-2016 IPR029060 PIN domain-like A4G23_RS18175 754aba48a18fdd513f2ba4a4c3c58078 440 Gene3D G3DSA:3.40.50.1010 14 72 5.5E-10 T 10-11-2016 IPR029060 PIN domain-like A4G23_RS18175 754aba48a18fdd513f2ba4a4c3c58078 440 Pfam PF13638 PIN domain 15 153 6.5E-26 T 10-11-2016 IPR002716 PIN domain A4G23_RS18175 754aba48a18fdd513f2ba4a4c3c58078 440 SMART SM00670 13 140 3.0E-13 T 10-11-2016 IPR002716 PIN domain A4G23_RS18175 754aba48a18fdd513f2ba4a4c3c58078 440 SUPERFAMILY SSF52540 229 392 1.07E-18 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS04200 825387cf66efcd5f4af67f9b287e1602 240 SUPERFAMILY SSF53807 3 235 7.06E-35 T 10-11-2016 A4G23_RS04200 825387cf66efcd5f4af67f9b287e1602 240 Gene3D G3DSA:3.40.50.1980 3 108 2.1E-19 T 10-11-2016 A4G23_RS04200 825387cf66efcd5f4af67f9b287e1602 240 Gene3D G3DSA:3.40.50.1980 122 235 5.9E-15 T 10-11-2016 A4G23_RS04200 825387cf66efcd5f4af67f9b287e1602 240 Pfam PF01497 Periplasmic binding protein 4 191 1.0E-8 T 10-11-2016 IPR002491 ABC transporter periplasmic binding domain GO:0005488 A4G23_RS09685 01b196e2682f6547511654adeba11306 381 SMART SM00862 297 367 4.1E-14 T 10-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4G23_RS09685 01b196e2682f6547511654adeba11306 381 Gene3D G3DSA:1.10.10.10 285 368 3.9E-14 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS09685 01b196e2682f6547511654adeba11306 381 Pfam PF00486 Transcriptional regulatory protein, C terminal 304 367 2.6E-13 T 10-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4G23_RS09685 01b196e2682f6547511654adeba11306 381 Gene3D G3DSA:3.40.50.10090 140 275 7.9E-37 T 10-11-2016 A4G23_RS09685 01b196e2682f6547511654adeba11306 381 Gene3D G3DSA:3.40.50.10090 9 138 6.5E-33 T 10-11-2016 A4G23_RS09685 01b196e2682f6547511654adeba11306 381 SUPERFAMILY SSF69618 12 272 4.58E-57 T 10-11-2016 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4G23_RS09685 01b196e2682f6547511654adeba11306 381 SUPERFAMILY SSF46894 281 367 6.52E-14 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS09685 01b196e2682f6547511654adeba11306 381 Pfam PF02602 Uroporphyrinogen-III synthase HemD 24 266 7.6E-42 T 10-11-2016 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4G23_RS02445 cb9b8192e0cbc99508bee0a2df7b9ed7 423 SUPERFAMILY SSF53850 44 416 4.69E-73 T 10-11-2016 A4G23_RS02445 cb9b8192e0cbc99508bee0a2df7b9ed7 423 Gene3D G3DSA:3.40.190.10 163 354 1.2E-48 T 10-11-2016 A4G23_RS02445 cb9b8192e0cbc99508bee0a2df7b9ed7 423 Pfam PF01547 Bacterial extracellular solute-binding protein 45 336 9.8E-29 T 10-11-2016 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 A4G23_RS02445 cb9b8192e0cbc99508bee0a2df7b9ed7 423 Gene3D G3DSA:3.40.190.10 38 162 1.7E-17 T 10-11-2016 A4G23_RS14680 c1434e2280579507b2aa4e0a78a7322f 236 Gene3D G3DSA:3.40.50.300 2 209 1.5E-57 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS14680 c1434e2280579507b2aa4e0a78a7322f 236 SUPERFAMILY SSF52540 2 201 2.6E-53 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS14680 c1434e2280579507b2aa4e0a78a7322f 236 Pfam PF00005 ABC transporter 4 148 3.0E-28 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS14680 c1434e2280579507b2aa4e0a78a7322f 236 SMART SM00382 12 195 1.3E-8 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS14680 c1434e2280579507b2aa4e0a78a7322f 236 ProSitePatterns PS00211 ABC transporters family signature. 121 135 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS21805 8d87871c42492b412c8a5a66ed31e6a7 214 SUPERFAMILY SSF46894 131 195 1.29E-15 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS21805 8d87871c42492b412c8a5a66ed31e6a7 214 SMART SM00448 1 120 1.3E-13 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS21805 8d87871c42492b412c8a5a66ed31e6a7 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 2.9E-8 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS21805 8d87871c42492b412c8a5a66ed31e6a7 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 2.9E-8 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS21805 8d87871c42492b412c8a5a66ed31e6a7 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 2.9E-8 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS21805 8d87871c42492b412c8a5a66ed31e6a7 214 SMART SM00421 148 210 3.1E-10 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS21805 8d87871c42492b412c8a5a66ed31e6a7 214 Gene3D G3DSA:3.40.50.2300 2 148 4.2E-28 T 10-11-2016 A4G23_RS21805 8d87871c42492b412c8a5a66ed31e6a7 214 SUPERFAMILY SSF52172 2 137 2.99E-20 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS21805 8d87871c42492b412c8a5a66ed31e6a7 214 Gene3D G3DSA:1.10.10.10 149 213 5.0E-21 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS21805 8d87871c42492b412c8a5a66ed31e6a7 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 195 2.6E-11 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS21805 8d87871c42492b412c8a5a66ed31e6a7 214 Pfam PF00072 Response regulator receiver domain 3 108 2.4E-18 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS23720 2d9cb5cd7c18e2bb003d3c5e4a30993f 340 SUPERFAMILY SSF52402 201 338 1.42E-15 T 10-11-2016 A4G23_RS23720 2d9cb5cd7c18e2bb003d3c5e4a30993f 340 PRINTS PR01438 Universal stress protein signature 125 137 4.6E-14 T 10-11-2016 IPR006015 Universal stress protein A A4G23_RS23720 2d9cb5cd7c18e2bb003d3c5e4a30993f 340 PRINTS PR01438 Universal stress protein signature 143 165 4.6E-14 T 10-11-2016 IPR006015 Universal stress protein A A4G23_RS23720 2d9cb5cd7c18e2bb003d3c5e4a30993f 340 PRINTS PR01438 Universal stress protein signature 15 33 4.6E-14 T 10-11-2016 IPR006015 Universal stress protein A A4G23_RS23720 2d9cb5cd7c18e2bb003d3c5e4a30993f 340 Gene3D G3DSA:3.40.50.620 199 338 2.7E-19 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS23720 2d9cb5cd7c18e2bb003d3c5e4a30993f 340 Pfam PF00582 Universal stress protein family 280 338 5.7E-8 T 10-11-2016 IPR006016 UspA GO:0006950 A4G23_RS23720 2d9cb5cd7c18e2bb003d3c5e4a30993f 340 Pfam PF00582 Universal stress protein family 16 165 8.5E-22 T 10-11-2016 IPR006016 UspA GO:0006950 A4G23_RS23720 2d9cb5cd7c18e2bb003d3c5e4a30993f 340 Gene3D G3DSA:3.40.50.620 11 166 7.4E-27 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS23720 2d9cb5cd7c18e2bb003d3c5e4a30993f 340 SUPERFAMILY SSF52402 16 167 4.69E-24 T 10-11-2016 A4G23_RS13085 c1a170fc576eb6964b7b0b196efbec45 324 Pfam PF02678 Pirin 41 146 3.8E-31 T 10-11-2016 IPR003829 Pirin, N-terminal domain A4G23_RS13085 c1a170fc576eb6964b7b0b196efbec45 324 SUPERFAMILY SSF51182 24 316 1.88E-83 T 10-11-2016 IPR011051 RmlC-like cupin domain A4G23_RS13085 c1a170fc576eb6964b7b0b196efbec45 324 Gene3D G3DSA:2.60.120.10 23 282 9.9E-79 T 10-11-2016 IPR014710 RmlC-like jelly roll fold A4G23_RS13085 c1a170fc576eb6964b7b0b196efbec45 324 Pfam PF05726 Pirin C-terminal cupin domain 201 309 4.5E-33 T 10-11-2016 IPR008778 Pirin, C-terminal domain A4G23_RS13085 c1a170fc576eb6964b7b0b196efbec45 324 PIRSF PIRSF006232 22 318 2.1E-92 T 10-11-2016 IPR012093 Pirin A4G23_RS00460 aacb3fbb566aa6327d1d82d3c004ccf6 401 Pfam PF01494 FAD binding domain 128 317 2.7E-8 T 10-11-2016 IPR002938 FAD-binding domain GO:0071949 A4G23_RS00460 aacb3fbb566aa6327d1d82d3c004ccf6 401 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 1.7E-13 T 10-11-2016 A4G23_RS00460 aacb3fbb566aa6327d1d82d3c004ccf6 401 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 263 278 1.7E-13 T 10-11-2016 A4G23_RS00460 aacb3fbb566aa6327d1d82d3c004ccf6 401 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 128 143 1.7E-13 T 10-11-2016 A4G23_RS00460 aacb3fbb566aa6327d1d82d3c004ccf6 401 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 278 294 1.7E-13 T 10-11-2016 A4G23_RS00460 aacb3fbb566aa6327d1d82d3c004ccf6 401 Gene3D G3DSA:3.50.50.60 253 348 2.1E-43 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS00460 aacb3fbb566aa6327d1d82d3c004ccf6 401 Gene3D G3DSA:3.50.50.60 96 165 2.1E-43 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS00460 aacb3fbb566aa6327d1d82d3c004ccf6 401 Gene3D G3DSA:3.50.50.60 1 42 2.1E-43 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS00460 aacb3fbb566aa6327d1d82d3c004ccf6 401 SUPERFAMILY SSF51905 2 149 5.37E-45 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS00460 aacb3fbb566aa6327d1d82d3c004ccf6 401 SUPERFAMILY SSF51905 250 352 5.37E-45 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS22645 7e1c40af4c23f93703b5de4abae70250 209 Gene3D G3DSA:3.40.50.2020 2 61 6.9E-40 T 10-11-2016 IPR029057 Phosphoribosyltransferase-like A4G23_RS22645 7e1c40af4c23f93703b5de4abae70250 209 Gene3D G3DSA:3.40.50.2020 93 202 6.9E-40 T 10-11-2016 IPR029057 Phosphoribosyltransferase-like A4G23_RS22645 7e1c40af4c23f93703b5de4abae70250 209 SUPERFAMILY SSF53271 1 208 9.57E-52 T 10-11-2016 IPR029057 Phosphoribosyltransferase-like A4G23_RS22645 7e1c40af4c23f93703b5de4abae70250 209 Pfam PF00156 Phosphoribosyl transferase domain 8 194 1.7E-25 T 10-11-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 A4G23_RS14635 5711ed8ea7caf31ba7a985edf616c9e6 193 Gene3D G3DSA:1.10.357.10 3 187 9.9E-35 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS14635 5711ed8ea7caf31ba7a985edf616c9e6 193 SUPERFAMILY SSF46689 6 74 5.64E-14 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS14635 5711ed8ea7caf31ba7a985edf616c9e6 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 56 7.8E-10 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS14635 5711ed8ea7caf31ba7a985edf616c9e6 193 SUPERFAMILY SSF48498 77 187 1.86E-22 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS22085 fa9bd05ac46b2b8ecfd65c87dc51440c 1024 Gene3D G3DSA:3.90.1150.10 906 1015 3.1E-20 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS22085 fa9bd05ac46b2b8ecfd65c87dc51440c 1024 Pfam PF08659 KR domain 192 361 4.4E-39 T 10-11-2016 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4G23_RS22085 fa9bd05ac46b2b8ecfd65c87dc51440c 1024 Pfam PF00155 Aminotransferase class I and II 674 1010 9.7E-52 T 10-11-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4G23_RS22085 fa9bd05ac46b2b8ecfd65c87dc51440c 1024 SUPERFAMILY SSF47336 429 507 1.18E-11 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS22085 fa9bd05ac46b2b8ecfd65c87dc51440c 1024 Gene3D G3DSA:1.10.1200.10 428 491 2.2E-10 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS22085 fa9bd05ac46b2b8ecfd65c87dc51440c 1024 Pfam PF00550 Phosphopantetheine attachment site 428 486 1.0E-9 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS22085 fa9bd05ac46b2b8ecfd65c87dc51440c 1024 Gene3D G3DSA:3.40.50.720 190 365 2.1E-30 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS22085 fa9bd05ac46b2b8ecfd65c87dc51440c 1024 SUPERFAMILY SSF53383 646 1021 1.86E-103 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS22085 fa9bd05ac46b2b8ecfd65c87dc51440c 1024 SUPERFAMILY SSF51735 190 409 4.17E-35 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS22085 fa9bd05ac46b2b8ecfd65c87dc51440c 1024 ProSitePatterns PS00012 Phosphopantetheine attachment site. 446 461 - T 10-11-2016 IPR006162 Phosphopantetheine attachment site A4G23_RS22085 fa9bd05ac46b2b8ecfd65c87dc51440c 1024 SUPERFAMILY SSF51735 5 181 3.94E-20 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS22085 fa9bd05ac46b2b8ecfd65c87dc51440c 1024 Gene3D G3DSA:3.40.640.10 687 905 2.8E-85 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS22085 fa9bd05ac46b2b8ecfd65c87dc51440c 1024 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 192 363 8.3E-33 T 10-11-2016 A4G23_RS05455 a3989138a23661796a289356a4171730 310 SUPERFAMILY SSF161098 69 297 4.06E-56 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS05455 a3989138a23661796a289356a4171730 310 Gene3D G3DSA:1.10.3720.10 20 299 4.5E-60 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS05455 a3989138a23661796a289356a4171730 310 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 101 301 9.9E-18 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS15220 110b99d8830fd36c8c8fc4cb525ae425 181 SUPERFAMILY SSF109854 5 165 3.82E-36 T 10-11-2016 A4G23_RS15220 110b99d8830fd36c8c8fc4cb525ae425 181 Gene3D G3DSA:1.20.120.450 6 168 1.5E-38 T 10-11-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase A4G23_RS15220 110b99d8830fd36c8c8fc4cb525ae425 181 Pfam PF04978 Protein of unknown function (DUF664) 17 166 1.1E-45 T 10-11-2016 IPR007061 Protein of unknown function DUF664 A4G23_RS23835 4fa6d14470477837e8701b7dd85570ff 168 Pfam PF00583 Acetyltransferase (GNAT) family 56 132 6.5E-12 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS23835 4fa6d14470477837e8701b7dd85570ff 168 SUPERFAMILY SSF55729 2 137 1.35E-24 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS23835 4fa6d14470477837e8701b7dd85570ff 168 Gene3D G3DSA:3.40.630.30 3 136 5.6E-24 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS21060 becbfc4b552186e8f7d7fc52d0a3d456 883 Pfam PF13185 GAF domain 307 442 4.4E-11 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS21060 becbfc4b552186e8f7d7fc52d0a3d456 883 SMART SM00331 660 877 2.2E-68 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS21060 becbfc4b552186e8f7d7fc52d0a3d456 883 Gene3D G3DSA:3.30.450.40 461 637 3.4E-21 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS21060 becbfc4b552186e8f7d7fc52d0a3d456 883 SMART SM00065 307 451 5.1E-11 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS21060 becbfc4b552186e8f7d7fc52d0a3d456 883 SMART SM00065 472 639 0.012 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS21060 becbfc4b552186e8f7d7fc52d0a3d456 883 SMART SM00091 160 226 0.0031 T 10-11-2016 IPR000014 PAS domain A4G23_RS21060 becbfc4b552186e8f7d7fc52d0a3d456 883 SUPERFAMILY SSF81606 669 877 1.88E-6 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS21060 becbfc4b552186e8f7d7fc52d0a3d456 883 Pfam PF13492 GAF domain 582 631 2.3E-6 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS21060 becbfc4b552186e8f7d7fc52d0a3d456 883 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 687 877 5.1E-43 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS21060 becbfc4b552186e8f7d7fc52d0a3d456 883 Pfam PF08448 PAS fold 168 269 1.2E-6 T 10-11-2016 IPR013656 PAS fold-4 A4G23_RS21060 becbfc4b552186e8f7d7fc52d0a3d456 883 Gene3D G3DSA:3.30.450.20 169 264 7.8E-12 T 10-11-2016 A4G23_RS21060 becbfc4b552186e8f7d7fc52d0a3d456 883 SUPERFAMILY SSF55785 168 264 3.62E-15 T 10-11-2016 IPR000014 PAS domain A4G23_RS21060 becbfc4b552186e8f7d7fc52d0a3d456 883 SUPERFAMILY SSF55781 457 514 9.65E-11 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS21060 becbfc4b552186e8f7d7fc52d0a3d456 883 SUPERFAMILY SSF55781 579 637 9.65E-11 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS21060 becbfc4b552186e8f7d7fc52d0a3d456 883 SUPERFAMILY SSF55781 308 446 3.93E-18 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS21060 becbfc4b552186e8f7d7fc52d0a3d456 883 Gene3D G3DSA:3.30.450.40 306 448 1.9E-19 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS21060 becbfc4b552186e8f7d7fc52d0a3d456 883 Pfam PF13581 Histidine kinase-like ATPase domain 28 139 1.4E-7 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS21060 becbfc4b552186e8f7d7fc52d0a3d456 883 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 167 268 1.1E-9 T 10-11-2016 IPR000014 PAS domain A4G23_RS02725 4fb9f7da7c2345747841ae746e0dc914 504 Gene3D G3DSA:3.90.660.10 322 419 7.3E-45 T 10-11-2016 A4G23_RS02725 4fb9f7da7c2345747841ae746e0dc914 504 Gene3D G3DSA:3.90.660.10 50 125 7.3E-45 T 10-11-2016 A4G23_RS02725 4fb9f7da7c2345747841ae746e0dc914 504 SUPERFAMILY SSF51905 18 337 2.03E-55 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS02725 4fb9f7da7c2345747841ae746e0dc914 504 SUPERFAMILY SSF51905 446 481 2.03E-55 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS02725 4fb9f7da7c2345747841ae746e0dc914 504 Gene3D G3DSA:3.40.50.720 19 49 1.5E-11 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS02725 4fb9f7da7c2345747841ae746e0dc914 504 Gene3D G3DSA:3.50.50.60 449 486 8.5E-23 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS02725 4fb9f7da7c2345747841ae746e0dc914 504 Gene3D G3DSA:3.50.50.60 226 318 8.5E-23 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS02725 4fb9f7da7c2345747841ae746e0dc914 504 PRINTS PR00757 Flavin-containing amine oxidase signature 322 341 9.2E-6 T 10-11-2016 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 A4G23_RS02725 4fb9f7da7c2345747841ae746e0dc914 504 PRINTS PR00757 Flavin-containing amine oxidase signature 20 39 9.2E-6 T 10-11-2016 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 A4G23_RS02725 4fb9f7da7c2345747841ae746e0dc914 504 PRINTS PR00757 Flavin-containing amine oxidase signature 463 480 9.2E-6 T 10-11-2016 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 A4G23_RS02725 4fb9f7da7c2345747841ae746e0dc914 504 Pfam PF01593 Flavin containing amine oxidoreductase 28 481 5.4E-54 T 10-11-2016 IPR002937 Amine oxidase GO:0016491|GO:0055114 A4G23_RS02725 4fb9f7da7c2345747841ae746e0dc914 504 SUPERFAMILY SSF54373 319 427 4.19E-26 T 10-11-2016 A4G23_RS21795 e6a07742b8ddf856e307b54f5a624ff1 253 Pfam PF00005 ABC transporter 35 181 1.5E-29 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS21795 e6a07742b8ddf856e307b54f5a624ff1 253 SMART SM00382 44 230 4.6E-14 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS21795 e6a07742b8ddf856e307b54f5a624ff1 253 Gene3D G3DSA:3.40.50.300 14 235 6.9E-69 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS21795 e6a07742b8ddf856e307b54f5a624ff1 253 SUPERFAMILY SSF52540 16 235 1.89E-69 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS21795 e6a07742b8ddf856e307b54f5a624ff1 253 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS23525 588b5da65c678a1bb0bb90332d6451ea 311 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 95 110 3.6E-10 T 10-11-2016 IPR008091 Ferrichrome-binding periplasmic protein A4G23_RS23525 588b5da65c678a1bb0bb90332d6451ea 311 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 223 241 3.6E-10 T 10-11-2016 IPR008091 Ferrichrome-binding periplasmic protein A4G23_RS23525 588b5da65c678a1bb0bb90332d6451ea 311 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 290 303 3.6E-10 T 10-11-2016 IPR008091 Ferrichrome-binding periplasmic protein A4G23_RS23525 588b5da65c678a1bb0bb90332d6451ea 311 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 63 81 3.6E-10 T 10-11-2016 IPR008091 Ferrichrome-binding periplasmic protein A4G23_RS23525 588b5da65c678a1bb0bb90332d6451ea 311 Gene3D G3DSA:3.40.50.1980 148 310 5.6E-42 T 10-11-2016 A4G23_RS23525 588b5da65c678a1bb0bb90332d6451ea 311 Pfam PF01497 Periplasmic binding protein 46 287 1.3E-26 T 10-11-2016 IPR002491 ABC transporter periplasmic binding domain GO:0005488 A4G23_RS23525 588b5da65c678a1bb0bb90332d6451ea 311 SUPERFAMILY SSF53807 41 309 9.81E-54 T 10-11-2016 A4G23_RS23525 588b5da65c678a1bb0bb90332d6451ea 311 Gene3D G3DSA:3.40.50.1980 28 147 5.1E-33 T 10-11-2016 A4G23_RS21675 3b7fe54e567fc0c3c4153216802d6e3c 330 PIRSF PIRSF019543 1 330 7.4E-128 T 10-11-2016 IPR014503 Clavaminate synthase GO:0005506|GO:0017000|GO:0033758|GO:0055114 A4G23_RS21675 3b7fe54e567fc0c3c4153216802d6e3c 330 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 132 307 1.1E-13 T 10-11-2016 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 A4G23_RS21675 3b7fe54e567fc0c3c4153216802d6e3c 330 TIGRFAM TIGR03946 viomycin_VioC: arginine beta-hydroxylase, Fe(II)/alpha-ketoglutarate-dependent 1 327 6.9E-167 T 10-11-2016 IPR023966 Arginine beta-hydroxylase, Fe2/alpha-ketoglutarate-dependent MetaCyc: PWY-6853 A4G23_RS21675 3b7fe54e567fc0c3c4153216802d6e3c 330 SUPERFAMILY SSF51197 13 319 3.71E-51 T 10-11-2016 A4G23_RS21675 3b7fe54e567fc0c3c4153216802d6e3c 330 Gene3D G3DSA:3.60.130.10 11 325 4.2E-57 T 10-11-2016 A4G23_RS17950 53f8bf8ada0b9cd6291731d2f240995c 410 SUPERFAMILY SSF53686 14 320 1.44E-90 T 10-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4G23_RS17950 53f8bf8ada0b9cd6291731d2f240995c 410 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 26 312 5.7E-79 T 10-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4G23_RS17950 53f8bf8ada0b9cd6291731d2f240995c 410 TIGRFAM TIGR01127 ilvA_1Cterm: threonine ammonia-lyase 31 406 4.9E-129 T 10-11-2016 IPR005789 Threonine dehydratase, catabolic GO:0004794|GO:0006567 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 A4G23_RS17950 53f8bf8ada0b9cd6291731d2f240995c 410 Gene3D G3DSA:3.40.50.1100 80 328 7.5E-73 T 10-11-2016 A4G23_RS17950 53f8bf8ada0b9cd6291731d2f240995c 410 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 52 65 - T 10-11-2016 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 A4G23_RS18715 b01976c3c3c33d4b32ac36c4410144fe 526 Gene3D G3DSA:3.40.50.1820 217 336 9.6E-54 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS18715 b01976c3c3c33d4b32ac36c4410144fe 526 Gene3D G3DSA:3.40.50.1820 88 172 9.6E-54 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS18715 b01976c3c3c33d4b32ac36c4410144fe 526 Gene3D G3DSA:3.40.50.1820 391 512 9.6E-54 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS18715 b01976c3c3c33d4b32ac36c4410144fe 526 Pfam PF08386 TAP-like protein 420 524 1.7E-30 T 10-11-2016 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal A4G23_RS18715 b01976c3c3c33d4b32ac36c4410144fe 526 SUPERFAMILY SSF53474 214 484 5.1E-23 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS18715 b01976c3c3c33d4b32ac36c4410144fe 526 SUPERFAMILY SSF53474 113 170 5.1E-23 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS16000 74a5063d2bdb3b4b2e20be1e5b09938e 399 PIRSF PIRSF004762 1 373 2.0E-108 T 10-11-2016 IPR005244 FO synthase, subunit 2-like GO:0016765|GO:0051188|GO:0051539 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 A4G23_RS16000 74a5063d2bdb3b4b2e20be1e5b09938e 399 Gene3D G3DSA:3.20.20.70 18 353 1.3E-62 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS16000 74a5063d2bdb3b4b2e20be1e5b09938e 399 Pfam PF04055 Radical SAM superfamily 65 238 1.4E-15 T 10-11-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 A4G23_RS16000 74a5063d2bdb3b4b2e20be1e5b09938e 399 TIGRFAM TIGR03699 menaquin_MqnC: dehypoxanthine futalosine cyclase 19 360 3.5E-138 T 10-11-2016 IPR022431 Cyclic dehypoxanthine futalosine synthase GO:0009234 KEGG: 00130+1.21.98.1|MetaCyc: PWY-7371|MetaCyc: PWY-7374 A4G23_RS16000 74a5063d2bdb3b4b2e20be1e5b09938e 399 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 57 360 5.2E-104 T 10-11-2016 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 A4G23_RS16000 74a5063d2bdb3b4b2e20be1e5b09938e 399 Hamap MF_00992 Cyclic dehypoxanthine futalosine synthase [mqnC]. 17 363 50.765 T 10-11-2016 IPR022431 Cyclic dehypoxanthine futalosine synthase GO:0009234 KEGG: 00130+1.21.98.1|MetaCyc: PWY-7371|MetaCyc: PWY-7374 A4G23_RS16000 74a5063d2bdb3b4b2e20be1e5b09938e 399 SUPERFAMILY SSF102114 17 352 5.62E-50 T 10-11-2016 A4G23_RS03660 4ac59362c42652ab61df0089d82534aa 456 SUPERFAMILY SSF48019 262 445 6.38E-72 T 10-11-2016 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 A4G23_RS03660 4ac59362c42652ab61df0089d82534aa 456 Gene3D G3DSA:1.10.3710.10 358 448 1.1E-27 T 10-11-2016 A4G23_RS03660 4ac59362c42652ab61df0089d82534aa 456 Pfam PF12002 MgsA AAA+ ATPase C terminal 277 442 1.7E-67 T 10-11-2016 IPR021886 MgsA AAA+ ATPase C-terminal A4G23_RS03660 4ac59362c42652ab61df0089d82534aa 456 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 65 169 8.3E-14 T 10-11-2016 IPR003959 ATPase, AAA-type, core GO:0005524 A4G23_RS03660 4ac59362c42652ab61df0089d82534aa 456 Gene3D G3DSA:3.40.50.300 11 170 5.4E-29 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS03660 4ac59362c42652ab61df0089d82534aa 456 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 69 88 1.2E-5 T 10-11-2016 A4G23_RS03660 4ac59362c42652ab61df0089d82534aa 456 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 331 350 1.2E-5 T 10-11-2016 A4G23_RS03660 4ac59362c42652ab61df0089d82534aa 456 SUPERFAMILY SSF52540 20 245 3.73E-39 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS03660 4ac59362c42652ab61df0089d82534aa 456 Gene3D G3DSA:1.20.272.10 258 356 6.8E-45 T 10-11-2016 A4G23_RS03660 4ac59362c42652ab61df0089d82534aa 456 SMART SM00382 61 182 1.6E-11 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS03660 4ac59362c42652ab61df0089d82534aa 456 Gene3D G3DSA:1.10.8.60 178 250 1.2E-7 T 10-11-2016 A4G23_RS03660 4ac59362c42652ab61df0089d82534aa 456 Pfam PF16193 AAA C-terminal domain 200 276 4.2E-25 T 10-11-2016 IPR032423 AAA ATPase, C-terminal domain A4G23_RS03710 5b283f82aca6948be20fcfd0ef33ea7d 567 SUPERFAMILY SSF82866 329 529 1.11E-30 T 10-11-2016 A4G23_RS03710 5b283f82aca6948be20fcfd0ef33ea7d 567 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 277 515 5.2E-65 T 10-11-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A4G23_RS03710 5b283f82aca6948be20fcfd0ef33ea7d 567 Pfam PF07549 SecD/SecF GG Motif 15 37 3.2E-4 T 10-11-2016 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site A4G23_RS03710 5b283f82aca6948be20fcfd0ef33ea7d 567 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 1 537 37.861 T 10-11-2016 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 A4G23_RS03710 5b283f82aca6948be20fcfd0ef33ea7d 567 Pfam PF02355 Protein export membrane protein 352 527 2.6E-12 T 10-11-2016 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial A4G23_RS03710 5b283f82aca6948be20fcfd0ef33ea7d 567 Gene3D G3DSA:1.20.1640.10 361 531 4.3E-22 T 10-11-2016 A4G23_RS03710 5b283f82aca6948be20fcfd0ef33ea7d 567 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 22 523 4.1E-108 T 10-11-2016 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 A4G23_RS25065 8a9568d56a739089c0939eacc5c4a0a3 202 SUPERFAMILY SSF88946 21 121 4.12E-23 T 10-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS25065 8a9568d56a739089c0939eacc5c4a0a3 202 Pfam PF04542 Sigma-70 region 2 40 107 1.2E-17 T 10-11-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS25065 8a9568d56a739089c0939eacc5c4a0a3 202 SUPERFAMILY SSF88659 133 193 3.36E-16 T 10-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS25065 8a9568d56a739089c0939eacc5c4a0a3 202 Pfam PF04545 Sigma-70, region 4 141 190 2.3E-17 T 10-11-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS25065 8a9568d56a739089c0939eacc5c4a0a3 202 Gene3D G3DSA:1.10.10.10 135 194 1.2E-18 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS25065 8a9568d56a739089c0939eacc5c4a0a3 202 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 34 191 7.3E-26 T 10-11-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS25065 8a9568d56a739089c0939eacc5c4a0a3 202 Gene3D G3DSA:1.10.1740.10 21 124 3.2E-25 T 10-11-2016 A4G23_RS02925 71c945e0a8f4832e9c6decfc78a5ae4c 533 SUPERFAMILY SSF56317 223 487 1.7E-40 T 10-11-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 A4G23_RS02925 71c945e0a8f4832e9c6decfc78a5ae4c 533 Pfam PF00795 Carbon-nitrogen hydrolase 231 474 2.1E-20 T 10-11-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 A4G23_RS02925 71c945e0a8f4832e9c6decfc78a5ae4c 533 Gene3D G3DSA:3.60.110.10 222 487 2.8E-34 T 10-11-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 A4G23_RS02925 71c945e0a8f4832e9c6decfc78a5ae4c 533 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 18 493 15.588 T 10-11-2016 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 A4G23_RS02925 71c945e0a8f4832e9c6decfc78a5ae4c 533 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 73 454 2.2E-82 T 10-11-2016 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 A4G23_RS04205 915c1a416faf9fe4dee090a94a4ea982 185 SUPERFAMILY SSF51182 55 179 1.02E-12 T 10-11-2016 IPR011051 RmlC-like cupin domain A4G23_RS04205 915c1a416faf9fe4dee090a94a4ea982 185 Pfam PF07883 Cupin domain 124 168 7.9E-8 T 10-11-2016 IPR013096 Cupin 2, conserved barrel A4G23_RS04205 915c1a416faf9fe4dee090a94a4ea982 185 SUPERFAMILY SSF47413 8 69 5.91E-13 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS04205 915c1a416faf9fe4dee090a94a4ea982 185 SMART SM00530 12 67 3.3E-10 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS04205 915c1a416faf9fe4dee090a94a4ea982 185 Gene3D G3DSA:2.60.120.10 89 180 2.6E-12 T 10-11-2016 IPR014710 RmlC-like jelly roll fold A4G23_RS04205 915c1a416faf9fe4dee090a94a4ea982 185 Gene3D G3DSA:1.10.260.40 9 88 1.7E-15 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS04205 915c1a416faf9fe4dee090a94a4ea982 185 Pfam PF13560 Helix-turn-helix domain 9 67 2.1E-11 T 10-11-2016 A4G23_RS16120 f5b411744e78f554637098dbde951800 304 Gene3D G3DSA:2.60.120.280 50 173 2.8E-9 T 10-11-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 A4G23_RS16120 f5b411744e78f554637098dbde951800 304 Gene3D G3DSA:1.10.10.60 250 297 6.1E-16 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS16120 f5b411744e78f554637098dbde951800 304 Gene3D G3DSA:1.10.10.60 213 249 5.5E-5 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS16120 f5b411744e78f554637098dbde951800 304 SUPERFAMILY SSF46689 249 297 8.06E-13 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS16120 f5b411744e78f554637098dbde951800 304 SMART SM00342 212 295 2.6E-26 T 10-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4G23_RS16120 f5b411744e78f554637098dbde951800 304 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 264 279 6.4E-6 T 10-11-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A4G23_RS16120 f5b411744e78f554637098dbde951800 304 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 279 295 6.4E-6 T 10-11-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A4G23_RS16120 f5b411744e78f554637098dbde951800 304 Pfam PF12833 Helix-turn-helix domain 219 296 1.4E-22 T 10-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4G23_RS16120 f5b411744e78f554637098dbde951800 304 Pfam PF02311 AraC-like ligand binding domain 51 112 2.9E-6 T 10-11-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 A4G23_RS16120 f5b411744e78f554637098dbde951800 304 SUPERFAMILY SSF51215 51 177 4.32E-12 T 10-11-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 A4G23_RS17905 5edfb7dac46857635287e721be58b194 225 SUPERFAMILY SSF55068 25 213 9.81E-76 T 10-11-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 A4G23_RS17905 5edfb7dac46857635287e721be58b194 225 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 48 203 3.5E-62 T 10-11-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 A4G23_RS17905 5edfb7dac46857635287e721be58b194 225 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 46 209 38.234 T 10-11-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 A4G23_RS17905 5edfb7dac46857635287e721be58b194 225 Pfam PF01625 Peptide methionine sulfoxide reductase 50 203 2.4E-63 T 10-11-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 A4G23_RS17905 5edfb7dac46857635287e721be58b194 225 Gene3D G3DSA:3.30.1060.10 24 203 2.2E-75 T 10-11-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 A4G23_RS08695 8229781b79388012f7b23bf33055c57a 399 SUPERFAMILY SSF54897 54 118 6.8E-7 T 10-11-2016 IPR009020 Proteinase propeptide inhibitor A4G23_RS08695 8229781b79388012f7b23bf33055c57a 399 Gene3D G3DSA:3.30.70.80 48 122 1.3E-14 T 10-11-2016 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 A4G23_RS08695 8229781b79388012f7b23bf33055c57a 399 PRINTS PR00723 Subtilisin serine protease family (S8) signature 189 202 4.7E-20 T 10-11-2016 IPR015500 Peptidase S8, subtilisin-related A4G23_RS08695 8229781b79388012f7b23bf33055c57a 399 PRINTS PR00723 Subtilisin serine protease family (S8) signature 342 358 4.7E-20 T 10-11-2016 IPR015500 Peptidase S8, subtilisin-related A4G23_RS08695 8229781b79388012f7b23bf33055c57a 399 PRINTS PR00723 Subtilisin serine protease family (S8) signature 151 170 4.7E-20 T 10-11-2016 IPR015500 Peptidase S8, subtilisin-related A4G23_RS08695 8229781b79388012f7b23bf33055c57a 399 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 156 167 - T 10-11-2016 IPR023827 Peptidase S8, subtilisin, Asp-active site A4G23_RS08695 8229781b79388012f7b23bf33055c57a 399 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 193 203 - T 10-11-2016 IPR022398 Peptidase S8, subtilisin, His-active site A4G23_RS08695 8229781b79388012f7b23bf33055c57a 399 Gene3D G3DSA:3.40.50.200 127 397 4.5E-85 T 10-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4G23_RS08695 8229781b79388012f7b23bf33055c57a 399 Pfam PF00082 Subtilase family 151 389 1.8E-40 T 10-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4G23_RS08695 8229781b79388012f7b23bf33055c57a 399 SUPERFAMILY SSF52743 126 386 1.57E-75 T 10-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4G23_RS08695 8229781b79388012f7b23bf33055c57a 399 Pfam PF05922 Peptidase inhibitor I9 67 116 4.0E-5 T 10-11-2016 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 A4G23_RS08695 8229781b79388012f7b23bf33055c57a 399 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 343 353 - T 10-11-2016 IPR023828 Peptidase S8, subtilisin, Ser-active site A4G23_RS06185 4879ec2f7980c0f18f7742bb991aa108 313 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 139 153 - T 10-11-2016 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4G23_RS06185 4879ec2f7980c0f18f7742bb991aa108 313 Pfam PF00849 RNA pseudouridylate synthase 93 247 1.6E-30 T 10-11-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4G23_RS06185 4879ec2f7980c0f18f7742bb991aa108 313 Gene3D G3DSA:3.10.290.10 19 61 6.1E-9 T 10-11-2016 IPR002942 RNA-binding S4 domain GO:0003723 A4G23_RS06185 4879ec2f7980c0f18f7742bb991aa108 313 SUPERFAMILY SSF55120 82 308 8.0E-69 T 10-11-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4G23_RS06185 4879ec2f7980c0f18f7742bb991aa108 313 Pfam PF01479 S4 domain 19 62 1.4E-6 T 10-11-2016 IPR002942 RNA-binding S4 domain GO:0003723 A4G23_RS06185 4879ec2f7980c0f18f7742bb991aa108 313 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 17 307 5.6E-85 T 10-11-2016 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4G23_RS06185 4879ec2f7980c0f18f7742bb991aa108 313 SUPERFAMILY SSF55174 19 112 1.57E-8 T 10-11-2016 A4G23_RS06185 4879ec2f7980c0f18f7742bb991aa108 313 SMART SM00363 19 103 0.0056 T 10-11-2016 IPR002942 RNA-binding S4 domain GO:0003723 A4G23_RS27280 bef011088baab13994e0ba4b0ee7f1a5 304 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 44 64 1.3E-6 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS27280 bef011088baab13994e0ba4b0ee7f1a5 304 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 20 33 1.3E-6 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS27280 bef011088baab13994e0ba4b0ee7f1a5 304 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 9 20 1.3E-6 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS27280 bef011088baab13994e0ba4b0ee7f1a5 304 Gene3D G3DSA:1.10.1660.10 6 62 2.3E-20 T 10-11-2016 A4G23_RS27280 bef011088baab13994e0ba4b0ee7f1a5 304 SUPERFAMILY SSF46955 8 107 9.52E-24 T 10-11-2016 IPR009061 Putative DNA-binding domain A4G23_RS27280 bef011088baab13994e0ba4b0ee7f1a5 304 SMART SM00422 8 77 8.1E-21 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS27280 bef011088baab13994e0ba4b0ee7f1a5 304 Pfam PF13411 MerR HTH family regulatory protein 9 76 1.7E-16 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS27280 bef011088baab13994e0ba4b0ee7f1a5 304 Gene3D G3DSA:1.10.1660.10 63 128 1.1E-8 T 10-11-2016 A4G23_RS09285 cb192837c06cfdb4728b77be23daf6df 450 Gene3D G3DSA:1.10.101.10 374 448 3.4E-10 T 10-11-2016 IPR002477 Peptidoglycan binding-like A4G23_RS09285 cb192837c06cfdb4728b77be23daf6df 450 Gene3D G3DSA:1.10.101.10 289 357 8.0E-5 T 10-11-2016 IPR002477 Peptidoglycan binding-like A4G23_RS09285 cb192837c06cfdb4728b77be23daf6df 450 SUPERFAMILY SSF54001 116 217 3.92E-8 T 10-11-2016 A4G23_RS09285 cb192837c06cfdb4728b77be23daf6df 450 SUPERFAMILY SSF47090 372 449 4.45E-10 T 10-11-2016 IPR002477 Peptidoglycan binding-like A4G23_RS09285 cb192837c06cfdb4728b77be23daf6df 450 Pfam PF01471 Putative peptidoglycan binding domain 388 448 1.0E-4 T 10-11-2016 IPR002477 Peptidoglycan binding-like A4G23_RS09285 cb192837c06cfdb4728b77be23daf6df 450 Gene3D G3DSA:3.90.1720.10 119 214 6.7E-12 T 10-11-2016 IPR000064 Endopeptidase, NLPC/P60 domain A4G23_RS09285 cb192837c06cfdb4728b77be23daf6df 450 SUPERFAMILY SSF47090 284 357 1.96E-5 T 10-11-2016 IPR002477 Peptidoglycan binding-like A4G23_RS03270 bad18a8e744641815652b3c4e6a443aa 554 SUPERFAMILY SSF51556 76 137 2.65E-38 T 10-11-2016 IPR032466 Metal-dependent hydrolase A4G23_RS03270 bad18a8e744641815652b3c4e6a443aa 554 SUPERFAMILY SSF51556 203 483 2.65E-38 T 10-11-2016 IPR032466 Metal-dependent hydrolase A4G23_RS03270 bad18a8e744641815652b3c4e6a443aa 554 Gene3D G3DSA:3.20.20.140 205 483 1.9E-37 T 10-11-2016 A4G23_RS03270 bad18a8e744641815652b3c4e6a443aa 554 SUPERFAMILY SSF51338 485 524 7.05E-13 T 10-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4G23_RS03270 bad18a8e744641815652b3c4e6a443aa 554 SUPERFAMILY SSF51338 15 77 7.05E-13 T 10-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4G23_RS03270 bad18a8e744641815652b3c4e6a443aa 554 Gene3D G3DSA:2.30.40.10 16 101 3.2E-13 T 10-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4G23_RS03270 bad18a8e744641815652b3c4e6a443aa 554 Pfam PF07969 Amidohydrolase family 65 549 3.4E-106 T 10-11-2016 IPR013108 Amidohydrolase 3 A4G23_RS13230 282df116348229b7c3c6c17b5bacd344 457 SUPERFAMILY SSF51230 3 96 4.32E-25 T 10-11-2016 IPR011053 Single hybrid motif A4G23_RS13230 282df116348229b7c3c6c17b5bacd344 457 Pfam PF02817 e3 binding domain 169 203 1.4E-13 T 10-11-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A4G23_RS13230 282df116348229b7c3c6c17b5bacd344 457 SUPERFAMILY SSF47005 165 205 8.11E-11 T 10-11-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A4G23_RS13230 282df116348229b7c3c6c17b5bacd344 457 Pfam PF00364 Biotin-requiring enzyme 6 77 2.5E-16 T 10-11-2016 IPR000089 Biotin/lipoyl attachment A4G23_RS13230 282df116348229b7c3c6c17b5bacd344 457 SUPERFAMILY SSF52777 218 454 5.34E-73 T 10-11-2016 A4G23_RS13230 282df116348229b7c3c6c17b5bacd344 457 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 230 454 2.1E-72 T 10-11-2016 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A4G23_RS13230 282df116348229b7c3c6c17b5bacd344 457 Gene3D G3DSA:3.30.559.10 220 454 4.9E-76 T 10-11-2016 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 A4G23_RS13230 282df116348229b7c3c6c17b5bacd344 457 Gene3D G3DSA:4.10.320.10 165 212 1.3E-16 T 10-11-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A4G23_RS13230 282df116348229b7c3c6c17b5bacd344 457 Gene3D G3DSA:2.40.50.100 4 92 3.1E-25 T 10-11-2016 A4G23_RS17840 2e6e2ddc122fed4ed9b60ec526a06774 200 SUPERFAMILY SSF52972 5 190 4.58E-53 T 10-11-2016 IPR029001 Inosine triphosphate pyrophosphatase-like A4G23_RS17840 2e6e2ddc122fed4ed9b60ec526a06774 200 Hamap MF_00528 Septum formation protein Maf [maf]. 6 195 28.407 T 10-11-2016 IPR003697 Maf-like protein GO:0005737 A4G23_RS17840 2e6e2ddc122fed4ed9b60ec526a06774 200 TIGRFAM TIGR00172 maf: septum formation protein Maf 6 189 9.5E-47 T 10-11-2016 IPR003697 Maf-like protein GO:0005737 A4G23_RS17840 2e6e2ddc122fed4ed9b60ec526a06774 200 Gene3D G3DSA:3.90.950.10 5 193 1.5E-59 T 10-11-2016 IPR029001 Inosine triphosphate pyrophosphatase-like A4G23_RS17840 2e6e2ddc122fed4ed9b60ec526a06774 200 PIRSF PIRSF006305 1 197 6.8E-43 T 10-11-2016 IPR003697 Maf-like protein GO:0005737 A4G23_RS17840 2e6e2ddc122fed4ed9b60ec526a06774 200 Pfam PF02545 Maf-like protein 6 190 9.8E-46 T 10-11-2016 IPR003697 Maf-like protein GO:0005737 A4G23_RS15065 e7ce85dc12f3df11776c413ecf48d093 386 Pfam PF13692 Glycosyl transferases group 1 201 334 9.0E-32 T 10-11-2016 A4G23_RS15065 e7ce85dc12f3df11776c413ecf48d093 386 Gene3D G3DSA:3.40.50.2000 165 348 2.5E-29 T 10-11-2016 A4G23_RS15065 e7ce85dc12f3df11776c413ecf48d093 386 SUPERFAMILY SSF53756 11 371 8.64E-77 T 10-11-2016 A4G23_RS15065 e7ce85dc12f3df11776c413ecf48d093 386 Pfam PF13439 Glycosyltransferase Family 4 16 175 5.1E-25 T 10-11-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A4G23_RS13670 99643f4be517f2ab3fe932ac308aa072 180 Gene3D G3DSA:1.10.10.10 6 78 3.2E-19 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS13670 99643f4be517f2ab3fe932ac308aa072 180 SUPERFAMILY SSF46785 11 78 5.24E-13 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS13670 99643f4be517f2ab3fe932ac308aa072 180 Pfam PF09339 IclR helix-turn-helix domain 13 63 1.1E-15 T 10-11-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4G23_RS13670 99643f4be517f2ab3fe932ac308aa072 180 SMART SM00346 11 98 9.8E-8 T 10-11-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4G23_RS18180 f176801c92e5086b0c4b38ea6cc43e6e 236 Pfam PF01464 Transglycosylase SLT domain 158 225 1.4E-6 T 10-11-2016 IPR008258 Transglycosylase SLT domain 1 A4G23_RS18180 f176801c92e5086b0c4b38ea6cc43e6e 236 SUPERFAMILY SSF53955 163 230 7.8E-11 T 10-11-2016 IPR023346 Lysozyme-like domain A4G23_RS18180 f176801c92e5086b0c4b38ea6cc43e6e 236 Gene3D G3DSA:1.10.530.10 162 229 6.3E-7 T 10-11-2016 A4G23_RS04380 6fb9312508c0395b6f13fa3eae581773 510 PIRSF PIRSF000538 10 510 6.0E-168 T 10-11-2016 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A4G23_RS04380 6fb9312508c0395b6f13fa3eae581773 510 Gene3D G3DSA:3.30.420.40 263 507 1.0E-101 T 10-11-2016 A4G23_RS04380 6fb9312508c0395b6f13fa3eae581773 510 Hamap MF_00186 Glycerol kinase [glpK]. 10 506 55.803 T 10-11-2016 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 A4G23_RS04380 6fb9312508c0395b6f13fa3eae581773 510 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 11 505 2.8E-227 T 10-11-2016 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 A4G23_RS04380 6fb9312508c0395b6f13fa3eae581773 510 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 269 459 1.8E-63 T 10-11-2016 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 A4G23_RS04380 6fb9312508c0395b6f13fa3eae581773 510 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 13 260 3.0E-79 T 10-11-2016 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 A4G23_RS04380 6fb9312508c0395b6f13fa3eae581773 510 Gene3D G3DSA:3.30.420.40 10 261 2.8E-108 T 10-11-2016 A4G23_RS04380 6fb9312508c0395b6f13fa3eae581773 510 SUPERFAMILY SSF53067 12 263 7.08E-92 T 10-11-2016 A4G23_RS04380 6fb9312508c0395b6f13fa3eae581773 510 SUPERFAMILY SSF53067 263 506 1.58E-81 T 10-11-2016 A4G23_RS04380 6fb9312508c0395b6f13fa3eae581773 510 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 371 391 - T 10-11-2016 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A4G23_RS17130 c95f8a8f1e8bd4f121a17de89084d866 139 Pfam PF05423 Mycobacterium membrane protein 8 133 1.0E-7 T 10-11-2016 IPR008693 Transport accessory protein MmpS A4G23_RS01575 be4e88e822510e1d1649e36299383b9d 405 Gene3D G3DSA:1.20.1250.20 14 196 3.2E-15 T 10-11-2016 A4G23_RS01575 be4e88e822510e1d1649e36299383b9d 405 Pfam PF07690 Major Facilitator Superfamily 14 356 5.0E-23 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS01575 be4e88e822510e1d1649e36299383b9d 405 SUPERFAMILY SSF103473 13 385 3.53E-29 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS02815 ec8468060b1b96aac92455d8bb28585d 148 SUPERFAMILY SSF46785 7 65 2.24E-18 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS02815 ec8468060b1b96aac92455d8bb28585d 148 Gene3D G3DSA:1.10.10.10 7 58 8.0E-25 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS02815 ec8468060b1b96aac92455d8bb28585d 148 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 6 22 8.2E-14 T 10-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 A4G23_RS02815 ec8468060b1b96aac92455d8bb28585d 148 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 33 52 8.2E-14 T 10-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 A4G23_RS02815 ec8468060b1b96aac92455d8bb28585d 148 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 22 33 8.2E-14 T 10-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 A4G23_RS02815 ec8468060b1b96aac92455d8bb28585d 148 Pfam PF13404 AsnC-type helix-turn-helix domain 7 47 8.0E-18 T 10-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 A4G23_RS02815 ec8468060b1b96aac92455d8bb28585d 148 Gene3D G3DSA:3.30.70.920 59 133 7.8E-20 T 10-11-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A4G23_RS02815 ec8468060b1b96aac92455d8bb28585d 148 SUPERFAMILY SSF54909 67 141 1.9E-17 T 10-11-2016 IPR011008 Dimeric alpha-beta barrel A4G23_RS02815 ec8468060b1b96aac92455d8bb28585d 148 Pfam PF01037 Lrp/AsnC ligand binding domain 72 138 1.4E-15 T 10-11-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A4G23_RS02815 ec8468060b1b96aac92455d8bb28585d 148 SMART SM00344 7 112 4.0E-37 T 10-11-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A4G23_RS04170 df415e2fec043a7095a6b40848570c47 458 Pfam PF00120 Glutamine synthetase, catalytic domain 121 453 2.0E-103 T 10-11-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4G23_RS04170 df415e2fec043a7095a6b40848570c47 458 Gene3D G3DSA:3.10.20.70 13 123 4.6E-12 T 10-11-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4G23_RS04170 df415e2fec043a7095a6b40848570c47 458 SUPERFAMILY SSF54368 11 119 6.15E-19 T 10-11-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4G23_RS04170 df415e2fec043a7095a6b40848570c47 458 SUPERFAMILY SSF55931 122 456 1.96E-101 T 10-11-2016 A4G23_RS04170 df415e2fec043a7095a6b40848570c47 458 Gene3D G3DSA:3.30.590.10 124 445 1.5E-98 T 10-11-2016 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 A4G23_RS04170 df415e2fec043a7095a6b40848570c47 458 SMART SM01230 120 376 2.1E-100 T 10-11-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4G23_RS11765 f9871c3fb66a46540fac51fe294d5f38 252 Gene3D G3DSA:1.10.3210.10 69 179 2.2E-10 T 10-11-2016 IPR006674 HD domain A4G23_RS11765 f9871c3fb66a46540fac51fe294d5f38 252 PIRSF PIRSF035170 11 251 2.2E-70 T 10-11-2016 IPR009218 Predicted HD phosphohydrolase A4G23_RS11765 f9871c3fb66a46540fac51fe294d5f38 252 SUPERFAMILY SSF109604 67 241 7.63E-32 T 10-11-2016 A4G23_RS13795 adcb2a7fc32561e507e93e50d33ba3c3 413 SUPERFAMILY SSF54909 58 406 3.04E-85 T 10-11-2016 IPR011008 Dimeric alpha-beta barrel A4G23_RS13795 adcb2a7fc32561e507e93e50d33ba3c3 413 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 63 401 1.7E-92 T 10-11-2016 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 A4G23_RS13795 adcb2a7fc32561e507e93e50d33ba3c3 413 Pfam PF04261 Dyp-type peroxidase family 63 400 5.4E-106 T 10-11-2016 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 A4G23_RS13795 adcb2a7fc32561e507e93e50d33ba3c3 413 TIGRFAM TIGR01412 tat_substr_1: Tat-translocated enzyme 5 412 5.3E-148 T 10-11-2016 IPR006313 Deferrochelatase/peroxidase EfeB GO:0004601|GO:0015684|GO:0020037|GO:0033212 A4G23_RS11705 483938f85ad757693d2ea7fbf62010bb 259 SUPERFAMILY SSF47413 2 54 2.17E-7 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS11705 483938f85ad757693d2ea7fbf62010bb 259 Pfam PF13560 Helix-turn-helix domain 2 61 3.1E-11 T 10-11-2016 A4G23_RS11705 483938f85ad757693d2ea7fbf62010bb 259 Gene3D G3DSA:1.10.260.40 2 55 9.0E-8 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS11705 483938f85ad757693d2ea7fbf62010bb 259 SMART SM00530 5 60 1.3E-5 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS16885 a25c5283d74f9b3cf4a540893f1a1ad6 217 Pfam PF00814 Glycoprotease family 32 144 6.5E-28 T 10-11-2016 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A4G23_RS16885 a25c5283d74f9b3cf4a540893f1a1ad6 217 Gene3D G3DSA:3.30.420.40 114 172 2.7E-13 T 10-11-2016 A4G23_RS16885 a25c5283d74f9b3cf4a540893f1a1ad6 217 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 3 201 6.2E-55 T 10-11-2016 IPR022496 tRNA threonylcarbamoyl adenosine modification protein YeaZ GO:0002949 A4G23_RS16885 a25c5283d74f9b3cf4a540893f1a1ad6 217 SUPERFAMILY SSF53067 2 102 2.94E-22 T 10-11-2016 A4G23_RS16885 a25c5283d74f9b3cf4a540893f1a1ad6 217 SUPERFAMILY SSF53067 107 199 1.23E-12 T 10-11-2016 A4G23_RS16885 a25c5283d74f9b3cf4a540893f1a1ad6 217 Gene3D G3DSA:3.30.420.40 2 113 3.6E-36 T 10-11-2016 A4G23_RS12515 b04d5cd8eb8c34e0445203127e104525 318 SMART SM00880 21 304 2.8E-5 T 10-11-2016 IPR007899 CHAD domain A4G23_RS12515 b04d5cd8eb8c34e0445203127e104525 318 Pfam PF05235 CHAD domain 25 269 1.7E-22 T 10-11-2016 IPR007899 CHAD domain A4G23_RS06070 e82692f26e43ce5273541c1d5dcdbe97 445 Pfam PF00815 Histidinol dehydrogenase 23 433 6.8E-157 T 10-11-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A4G23_RS06070 e82692f26e43ce5273541c1d5dcdbe97 445 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 36 432 4.6E-143 T 10-11-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A4G23_RS06070 e82692f26e43ce5273541c1d5dcdbe97 445 PIRSF PIRSF000099 5 435 3.1E-162 T 10-11-2016 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A4G23_RS06070 e82692f26e43ce5273541c1d5dcdbe97 445 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 233 265 - T 10-11-2016 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 A4G23_RS06070 e82692f26e43ce5273541c1d5dcdbe97 445 Gene3D G3DSA:3.40.50.1980 30 243 4.8E-77 T 10-11-2016 A4G23_RS06070 e82692f26e43ce5273541c1d5dcdbe97 445 SUPERFAMILY SSF53720 16 437 2.75E-73 T 10-11-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A4G23_RS06070 e82692f26e43ce5273541c1d5dcdbe97 445 PRINTS PR00083 Histidinol dehydrogenase signature 204 229 1.7E-84 T 10-11-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A4G23_RS06070 e82692f26e43ce5273541c1d5dcdbe97 445 PRINTS PR00083 Histidinol dehydrogenase signature 233 254 1.7E-84 T 10-11-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A4G23_RS06070 e82692f26e43ce5273541c1d5dcdbe97 445 PRINTS PR00083 Histidinol dehydrogenase signature 137 163 1.7E-84 T 10-11-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A4G23_RS06070 e82692f26e43ce5273541c1d5dcdbe97 445 PRINTS PR00083 Histidinol dehydrogenase signature 36 60 1.7E-84 T 10-11-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A4G23_RS06070 e82692f26e43ce5273541c1d5dcdbe97 445 PRINTS PR00083 Histidinol dehydrogenase signature 326 351 1.7E-84 T 10-11-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A4G23_RS06070 e82692f26e43ce5273541c1d5dcdbe97 445 PRINTS PR00083 Histidinol dehydrogenase signature 255 274 1.7E-84 T 10-11-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A4G23_RS06070 e82692f26e43ce5273541c1d5dcdbe97 445 PRINTS PR00083 Histidinol dehydrogenase signature 174 200 1.7E-84 T 10-11-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A4G23_RS06070 e82692f26e43ce5273541c1d5dcdbe97 445 PRINTS PR00083 Histidinol dehydrogenase signature 367 385 1.7E-84 T 10-11-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A4G23_RS06070 e82692f26e43ce5273541c1d5dcdbe97 445 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 5 433 38.904 T 10-11-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A4G23_RS03130 513cf491f1c2fefe798b923e72b705e6 670 Gene3D G3DSA:3.40.50.980 282 441 1.4E-15 T 10-11-2016 A4G23_RS03130 513cf491f1c2fefe798b923e72b705e6 670 SUPERFAMILY SSF56801 48 643 7.85E-125 T 10-11-2016 A4G23_RS03130 513cf491f1c2fefe798b923e72b705e6 670 Pfam PF00501 AMP-binding enzyme 106 536 7.6E-48 T 10-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A4G23_RS03130 513cf491f1c2fefe798b923e72b705e6 670 TIGRFAM TIGR01217 ac_ac_CoA_syn: acetoacetate-CoA ligase 14 663 0.0 T 10-11-2016 IPR005914 Acetoacetyl-CoA synthase GO:0006629|GO:0030729 KEGG: 00280+6.2.1.16|KEGG: 00650+6.2.1.16|Reactome: R-HSA-77111 A4G23_RS03130 513cf491f1c2fefe798b923e72b705e6 670 ProSitePatterns PS00455 Putative AMP-binding domain signature. 276 287 - T 10-11-2016 IPR020845 AMP-binding, conserved site A4G23_RS03130 513cf491f1c2fefe798b923e72b705e6 670 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 48 104 1.8E-11 T 10-11-2016 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118 A4G23_RS03130 513cf491f1c2fefe798b923e72b705e6 670 Gene3D G3DSA:3.30.300.30 535 625 2.2E-12 T 10-11-2016 A4G23_RS03130 513cf491f1c2fefe798b923e72b705e6 670 Gene3D G3DSA:3.40.50.980 106 281 2.3E-27 T 10-11-2016 A4G23_RS03130 513cf491f1c2fefe798b923e72b705e6 670 Pfam PF13193 AMP-binding enzyme C-terminal domain 549 624 5.5E-6 T 10-11-2016 IPR025110 AMP-binding enzyme C-terminal domain A4G23_RS00785 2a2302d8ec6982a7fcc42391a1d6d87d 959 SUPERFAMILY SSF46894 883 945 5.78E-16 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS00785 2a2302d8ec6982a7fcc42391a1d6d87d 959 Gene3D G3DSA:1.10.10.10 887 945 1.4E-17 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS00785 2a2302d8ec6982a7fcc42391a1d6d87d 959 Pfam PF00196 Bacterial regulatory proteins, luxR family 890 944 3.5E-12 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS00785 2a2302d8ec6982a7fcc42391a1d6d87d 959 Gene3D G3DSA:3.40.50.300 143 144 9.3E-7 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS00785 2a2302d8ec6982a7fcc42391a1d6d87d 959 Gene3D G3DSA:3.40.50.300 219 238 9.3E-7 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS00785 2a2302d8ec6982a7fcc42391a1d6d87d 959 Gene3D G3DSA:3.40.50.300 17 78 9.3E-7 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS00785 2a2302d8ec6982a7fcc42391a1d6d87d 959 SUPERFAMILY SSF48452 603 735 2.49E-8 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS00785 2a2302d8ec6982a7fcc42391a1d6d87d 959 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 905 921 4.4E-7 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS00785 2a2302d8ec6982a7fcc42391a1d6d87d 959 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 921 933 4.4E-7 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS00785 2a2302d8ec6982a7fcc42391a1d6d87d 959 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 891 905 4.4E-7 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS00785 2a2302d8ec6982a7fcc42391a1d6d87d 959 Gene3D G3DSA:1.25.40.10 435 464 5.1E-13 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS00785 2a2302d8ec6982a7fcc42391a1d6d87d 959 Gene3D G3DSA:1.25.40.10 499 782 5.1E-13 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS00785 2a2302d8ec6982a7fcc42391a1d6d87d 959 Gene3D G3DSA:1.25.40.10 792 866 5.6E-4 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS00785 2a2302d8ec6982a7fcc42391a1d6d87d 959 Pfam PF13191 AAA ATPase domain 11 165 2.5E-13 T 10-11-2016 A4G23_RS00785 2a2302d8ec6982a7fcc42391a1d6d87d 959 SMART SM00421 888 945 3.2E-18 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS00785 2a2302d8ec6982a7fcc42391a1d6d87d 959 SUPERFAMILY SSF52540 198 265 3.18E-13 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS00785 2a2302d8ec6982a7fcc42391a1d6d87d 959 SUPERFAMILY SSF52540 4 170 3.18E-13 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS02370 948d6ac5b166221289ce528b7ab00039 374 SUPERFAMILY SSF51905 169 353 5.7E-7 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS02370 948d6ac5b166221289ce528b7ab00039 374 Gene3D G3DSA:3.50.50.60 151 206 3.2E-21 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS02370 948d6ac5b166221289ce528b7ab00039 374 Gene3D G3DSA:3.50.50.60 252 289 3.2E-21 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS02370 948d6ac5b166221289ce528b7ab00039 374 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 169 187 1.5E-7 T 10-11-2016 A4G23_RS02370 948d6ac5b166221289ce528b7ab00039 374 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.5E-7 T 10-11-2016 A4G23_RS02370 948d6ac5b166221289ce528b7ab00039 374 SUPERFAMILY SSF51905 3 224 1.08E-36 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS02370 948d6ac5b166221289ce528b7ab00039 374 Gene3D G3DSA:3.50.50.60 4 150 1.1E-20 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS02370 948d6ac5b166221289ce528b7ab00039 374 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 7 203 2.6E-20 T 10-11-2016 A4G23_RS02370 948d6ac5b166221289ce528b7ab00039 374 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 5 27 2.8E-12 T 10-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4G23_RS02370 948d6ac5b166221289ce528b7ab00039 374 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 165 189 2.8E-12 T 10-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4G23_RS02370 948d6ac5b166221289ce528b7ab00039 374 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 126 134 2.8E-12 T 10-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4G23_RS19030 ebaeb9a7661010a4e49cc92dbcb25c3d 261 ProSitePatterns PS01161 Glucosamine/galactosamine-6-phosphate isomerases signature. 120 138 - T 10-11-2016 IPR018321 Glucosamine-6-phosphate isomerase, conserved site GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 A4G23_RS19030 ebaeb9a7661010a4e49cc92dbcb25c3d 261 TIGRFAM TIGR00502 nagB: glucosamine-6-phosphate deaminase 3 245 4.6E-75 T 10-11-2016 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 A4G23_RS19030 ebaeb9a7661010a4e49cc92dbcb25c3d 261 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 10 227 1.0E-22 T 10-11-2016 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 A4G23_RS19030 ebaeb9a7661010a4e49cc92dbcb25c3d 261 Hamap MF_01241 Glucosamine-6-phosphate deaminase [nagB]. 1 242 39.052 T 10-11-2016 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 A4G23_RS19030 ebaeb9a7661010a4e49cc92dbcb25c3d 261 SUPERFAMILY SSF100950 2 251 3.39E-86 T 10-11-2016 A4G23_RS19030 ebaeb9a7661010a4e49cc92dbcb25c3d 261 Gene3D G3DSA:3.40.50.1360 2 246 6.8E-89 T 10-11-2016 A4G23_RS12470 cb0bc17f8fc0a25d2ce28e30652b7145 407 Gene3D G3DSA:2.40.10.10 180 255 4.9E-28 T 10-11-2016 A4G23_RS12470 cb0bc17f8fc0a25d2ce28e30652b7145 407 PRINTS PR00834 HtrA/DegQ protease family signature 193 205 8.3E-24 T 10-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4G23_RS12470 cb0bc17f8fc0a25d2ce28e30652b7145 407 PRINTS PR00834 HtrA/DegQ protease family signature 214 234 8.3E-24 T 10-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4G23_RS12470 cb0bc17f8fc0a25d2ce28e30652b7145 407 PRINTS PR00834 HtrA/DegQ protease family signature 355 372 8.3E-24 T 10-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4G23_RS12470 cb0bc17f8fc0a25d2ce28e30652b7145 407 PRINTS PR00834 HtrA/DegQ protease family signature 333 350 8.3E-24 T 10-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4G23_RS12470 cb0bc17f8fc0a25d2ce28e30652b7145 407 Gene3D G3DSA:2.40.10.10 256 289 5.2E-38 T 10-11-2016 A4G23_RS12470 cb0bc17f8fc0a25d2ce28e30652b7145 407 Gene3D G3DSA:2.40.10.10 333 404 5.2E-38 T 10-11-2016 A4G23_RS12470 cb0bc17f8fc0a25d2ce28e30652b7145 407 Pfam PF13365 Trypsin-like peptidase domain 184 362 2.1E-28 T 10-11-2016 A4G23_RS12470 cb0bc17f8fc0a25d2ce28e30652b7145 407 SUPERFAMILY SSF50494 159 286 1.81E-50 T 10-11-2016 IPR009003 Peptidase S1, PA clan A4G23_RS12470 cb0bc17f8fc0a25d2ce28e30652b7145 407 SUPERFAMILY SSF50494 337 401 1.81E-50 T 10-11-2016 IPR009003 Peptidase S1, PA clan A4G23_RS02880 de05469de240775f614ec8d698ee1e35 150 Gene3D G3DSA:3.10.129.10 10 149 2.4E-36 T 10-11-2016 IPR029069 HotDog domain A4G23_RS02880 de05469de240775f614ec8d698ee1e35 150 Pfam PF14539 Domain of unknown function (DUF4442) 11 145 1.9E-23 T 10-11-2016 IPR027961 Protein of unknown function DUF4442 A4G23_RS02880 de05469de240775f614ec8d698ee1e35 150 SUPERFAMILY SSF54637 1 148 9.24E-18 T 10-11-2016 IPR029069 HotDog domain A4G23_RS23980 3d85220eb4128f6e20828be54b7af30d 241 SUPERFAMILY SSF53474 3 233 8.6E-28 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS23980 3d85220eb4128f6e20828be54b7af30d 241 Gene3D G3DSA:3.40.50.1820 3 235 1.2E-20 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS23980 3d85220eb4128f6e20828be54b7af30d 241 Pfam PF00975 Thioesterase domain 4 223 1.2E-23 T 10-11-2016 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 A4G23_RS23980 3d85220eb4128f6e20828be54b7af30d 241 SMART SM00824 Thioesterase 10 233 0.0044 T 10-11-2016 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 A4G23_RS00565 b2d0a625c5a13665ec0c662e2daf9313 270 Gene3D G3DSA:3.10.180.10 24 134 1.4E-25 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS00565 b2d0a625c5a13665ec0c662e2daf9313 270 Gene3D G3DSA:3.10.180.10 149 264 9.6E-14 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS00565 b2d0a625c5a13665ec0c662e2daf9313 270 SUPERFAMILY SSF54593 151 263 5.19E-10 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS00565 b2d0a625c5a13665ec0c662e2daf9313 270 SUPERFAMILY SSF54593 25 145 3.44E-16 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS22935 96d3482ea6f53ed9b649a7e1994976de 220 SUPERFAMILY SSF52172 18 121 2.13E-11 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS22935 96d3482ea6f53ed9b649a7e1994976de 220 Gene3D G3DSA:3.40.50.2300 20 117 3.0E-9 T 10-11-2016 A4G23_RS22935 96d3482ea6f53ed9b649a7e1994976de 220 SMART SM00421 156 213 1.0E-21 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS22935 96d3482ea6f53ed9b649a7e1994976de 220 Gene3D G3DSA:1.10.10.10 143 218 1.5E-20 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS22935 96d3482ea6f53ed9b649a7e1994976de 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 189 201 2.8E-12 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS22935 96d3482ea6f53ed9b649a7e1994976de 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 173 2.8E-12 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS22935 96d3482ea6f53ed9b649a7e1994976de 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 189 2.8E-12 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS22935 96d3482ea6f53ed9b649a7e1994976de 220 ProSitePatterns PS00622 LuxR-type HTH domain signature. 173 200 - T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS22935 96d3482ea6f53ed9b649a7e1994976de 220 Pfam PF00196 Bacterial regulatory proteins, luxR family 159 213 2.5E-16 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS22935 96d3482ea6f53ed9b649a7e1994976de 220 SUPERFAMILY SSF46894 146 219 1.63E-18 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS22935 96d3482ea6f53ed9b649a7e1994976de 220 Pfam PF00072 Response regulator receiver domain 26 116 2.2E-5 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS21380 81e96309cfeacb1a3dc86b8be06a50f1 288 Pfam PF00392 Bacterial regulatory proteins, gntR family 62 121 2.2E-14 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS21380 81e96309cfeacb1a3dc86b8be06a50f1 288 SMART SM00895 150 274 2.4E-22 T 10-11-2016 IPR011711 GntR, C-terminal A4G23_RS21380 81e96309cfeacb1a3dc86b8be06a50f1 288 Pfam PF07729 FCD domain 150 272 2.2E-23 T 10-11-2016 IPR011711 GntR, C-terminal A4G23_RS21380 81e96309cfeacb1a3dc86b8be06a50f1 288 SMART SM00345 63 121 1.1E-11 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS21380 81e96309cfeacb1a3dc86b8be06a50f1 288 SUPERFAMILY SSF48008 147 273 4.97E-26 T 10-11-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal A4G23_RS21380 81e96309cfeacb1a3dc86b8be06a50f1 288 SUPERFAMILY SSF46785 55 125 1.94E-16 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS21380 81e96309cfeacb1a3dc86b8be06a50f1 288 Gene3D G3DSA:1.20.120.530 147 273 1.0E-25 T 10-11-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal A4G23_RS21380 81e96309cfeacb1a3dc86b8be06a50f1 288 Gene3D G3DSA:1.10.10.10 52 123 6.5E-20 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS01070 6ac54761a81538e19ed433d923da6faf 412 Pfam PF00534 Glycosyl transferases group 1 222 380 2.0E-37 T 10-11-2016 IPR001296 Glycosyl transferase, family 1 A4G23_RS01070 6ac54761a81538e19ed433d923da6faf 412 Gene3D G3DSA:3.40.50.2000 188 380 8.3E-40 T 10-11-2016 A4G23_RS01070 6ac54761a81538e19ed433d923da6faf 412 Pfam PF13439 Glycosyltransferase Family 4 30 205 5.2E-39 T 10-11-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A4G23_RS01070 6ac54761a81538e19ed433d923da6faf 412 SUPERFAMILY SSF53756 29 403 4.71E-94 T 10-11-2016 A4G23_RS20195 132cfd6383a6a43f4e5f2fd236e8b6d5 187 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 1 14 1.7E-5 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS20195 132cfd6383a6a43f4e5f2fd236e8b6d5 187 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 45 1.7E-5 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS20195 132cfd6383a6a43f4e5f2fd236e8b6d5 187 Pfam PF00440 Bacterial regulatory proteins, tetR family 2 46 2.7E-11 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS20195 132cfd6383a6a43f4e5f2fd236e8b6d5 187 SUPERFAMILY SSF48498 71 179 8.9E-15 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS20195 132cfd6383a6a43f4e5f2fd236e8b6d5 187 Pfam PF13977 Bacterial transcriptional repressor 73 183 2.8E-23 T 10-11-2016 A4G23_RS20195 132cfd6383a6a43f4e5f2fd236e8b6d5 187 SUPERFAMILY SSF46689 2 65 3.49E-11 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS20195 132cfd6383a6a43f4e5f2fd236e8b6d5 187 Gene3D G3DSA:1.10.357.10 2 182 2.2E-31 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS08190 879b986eec014763e05fb141a298a66e 427 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 180 1.6E-34 T 10-11-2016 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A4G23_RS08190 879b986eec014763e05fb141a298a66e 427 SUPERFAMILY SSF52413 307 419 1.96E-10 T 10-11-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A4G23_RS08190 879b986eec014763e05fb141a298a66e 427 Gene3D G3DSA:3.40.50.720 1 234 1.1E-47 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS08190 879b986eec014763e05fb141a298a66e 427 Gene3D G3DSA:3.40.50.720 244 419 5.7E-28 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS08190 879b986eec014763e05fb141a298a66e 427 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 214 298 3.5E-17 T 10-11-2016 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A4G23_RS08190 879b986eec014763e05fb141a298a66e 427 SMART SM00984 322 414 4.1E-6 T 10-11-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A4G23_RS08190 879b986eec014763e05fb141a298a66e 427 SUPERFAMILY SSF48179 214 304 5.78E-20 T 10-11-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A4G23_RS08190 879b986eec014763e05fb141a298a66e 427 SUPERFAMILY SSF51735 1 193 7.75E-43 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS08190 879b986eec014763e05fb141a298a66e 427 PIRSF PIRSF500136 1 425 5.5E-101 T 10-11-2016 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 A4G23_RS08190 879b986eec014763e05fb141a298a66e 427 PIRSF PIRSF000124 1 426 2.2E-46 T 10-11-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A4G23_RS08190 879b986eec014763e05fb141a298a66e 427 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 410 1.9E-87 T 10-11-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A4G23_RS25180 59fca0d79b005b88c5ef436076fc8656 163 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 26 68 - T 10-11-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A4G23_RS25180 59fca0d79b005b88c5ef436076fc8656 163 Gene3D G3DSA:1.10.10.60 27 69 8.4E-11 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS25180 59fca0d79b005b88c5ef436076fc8656 163 SUPERFAMILY SSF46689 25 74 1.57E-9 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS25180 59fca0d79b005b88c5ef436076fc8656 163 Gene3D G3DSA:1.10.10.60 1 26 1.2E-6 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS25180 59fca0d79b005b88c5ef436076fc8656 163 SMART SM00342 1 72 2.1E-14 T 10-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4G23_RS25180 59fca0d79b005b88c5ef436076fc8656 163 Pfam PF12833 Helix-turn-helix domain 1 69 2.3E-16 T 10-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4G23_RS13440 d0ea63198602a3bbb7b81bf33b7c626d 886 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 13 837 23.073 T 10-11-2016 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A4G23_RS13440 d0ea63198602a3bbb7b81bf33b7c626d 886 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 49 492 2.8E-150 T 10-11-2016 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4G23_RS13440 d0ea63198602a3bbb7b81bf33b7c626d 886 SUPERFAMILY SSF101904 519 843 4.71E-98 T 10-11-2016 A4G23_RS13440 d0ea63198602a3bbb7b81bf33b7c626d 886 Gene3D G3DSA:3.90.199.10 47 256 5.3E-114 T 10-11-2016 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 A4G23_RS13440 d0ea63198602a3bbb7b81bf33b7c626d 886 Gene3D G3DSA:3.90.199.10 354 418 5.3E-114 T 10-11-2016 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 A4G23_RS13440 d0ea63198602a3bbb7b81bf33b7c626d 886 SUPERFAMILY SSF56719 47 507 2.35E-171 T 10-11-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 A4G23_RS13440 d0ea63198602a3bbb7b81bf33b7c626d 886 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 789 833 2.0E-11 T 10-11-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A4G23_RS13440 d0ea63198602a3bbb7b81bf33b7c626d 886 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 631 666 8.0E-8 T 10-11-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A4G23_RS13440 d0ea63198602a3bbb7b81bf33b7c626d 886 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 740 785 1.7E-12 T 10-11-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A4G23_RS13440 d0ea63198602a3bbb7b81bf33b7c626d 886 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 524 569 1.7E-14 T 10-11-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A4G23_RS13440 d0ea63198602a3bbb7b81bf33b7c626d 886 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 686 734 8.4E-12 T 10-11-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A4G23_RS13440 d0ea63198602a3bbb7b81bf33b7c626d 886 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 575 610 9.2E-9 T 10-11-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A4G23_RS13440 d0ea63198602a3bbb7b81bf33b7c626d 886 Gene3D G3DSA:2.120.10.90 516 834 1.3E-117 T 10-11-2016 A4G23_RS13440 d0ea63198602a3bbb7b81bf33b7c626d 886 Gene3D G3DSA:3.30.1360.40 257 353 3.4E-34 T 10-11-2016 IPR024946 Arginine repressor C-terminal-like domain A4G23_RS13440 d0ea63198602a3bbb7b81bf33b7c626d 886 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 25 835 0.0 T 10-11-2016 A4G23_RS13440 d0ea63198602a3bbb7b81bf33b7c626d 886 SMART SM00434 28 485 9.7E-283 T 10-11-2016 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4G23_RS05565 c7ef9a7bb3a802699126dcaf8a1860e3 254 Pfam PF00005 ABC transporter 23 174 6.0E-22 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS05565 c7ef9a7bb3a802699126dcaf8a1860e3 254 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 4 245 9.8E-105 T 10-11-2016 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524|GO:0006810 A4G23_RS05565 c7ef9a7bb3a802699126dcaf8a1860e3 254 SMART SM00382 32 225 5.4E-5 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS05565 c7ef9a7bb3a802699126dcaf8a1860e3 254 SUPERFAMILY SSF52540 4 234 6.35E-43 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05565 c7ef9a7bb3a802699126dcaf8a1860e3 254 Gene3D G3DSA:3.40.50.300 3 235 7.5E-48 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS25915 81fed4c5e54a0664da7e5f81f5a24fb8 130 TIGRFAM TIGR01068 thioredoxin: thioredoxin 7 102 8.8E-29 T 10-11-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 A4G23_RS25915 81fed4c5e54a0664da7e5f81f5a24fb8 130 Gene3D G3DSA:3.40.30.10 3 101 1.4E-31 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS25915 81fed4c5e54a0664da7e5f81f5a24fb8 130 Pfam PF00085 Thioredoxin 3 100 1.6E-26 T 10-11-2016 IPR013766 Thioredoxin domain GO:0045454 A4G23_RS25915 81fed4c5e54a0664da7e5f81f5a24fb8 130 SUPERFAMILY SSF52833 3 102 4.23E-32 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS25915 81fed4c5e54a0664da7e5f81f5a24fb8 130 ProSitePatterns PS00194 Thioredoxin family active site. 22 40 - T 10-11-2016 IPR017937 Thioredoxin, conserved site GO:0045454 A4G23_RS25915 81fed4c5e54a0664da7e5f81f5a24fb8 130 PRINTS PR00421 Thioredoxin family signature 29 38 7.9E-7 T 10-11-2016 A4G23_RS25915 81fed4c5e54a0664da7e5f81f5a24fb8 130 PRINTS PR00421 Thioredoxin family signature 21 29 7.9E-7 T 10-11-2016 A4G23_RS25915 81fed4c5e54a0664da7e5f81f5a24fb8 130 PRINTS PR00421 Thioredoxin family signature 68 79 7.9E-7 T 10-11-2016 A4G23_RS07600 8580274ebbf58cc661fd37c682b4fdab 187 SUPERFAMILY SSF53383 6 176 2.54E-24 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS07600 8580274ebbf58cc661fd37c682b4fdab 187 Pfam PF12897 Alanine-glyoxylate amino-transferase 1 185 4.7E-86 T 10-11-2016 IPR024551 Aminotransferase, putative A4G23_RS07600 8580274ebbf58cc661fd37c682b4fdab 187 Gene3D G3DSA:3.90.1150.10 18 185 5.5E-59 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS12840 ecc24e0a28f74cbdaf64341323aaa73d 1319 Pfam PF04408 Helicase associated domain (HA2) 463 554 3.0E-19 T 10-11-2016 IPR007502 Helicase-associated domain GO:0004386 A4G23_RS12840 ecc24e0a28f74cbdaf64341323aaa73d 1319 Pfam PF07717 Oligonucleotide/oligosaccharide-binding (OB)-fold 614 707 6.1E-15 T 10-11-2016 IPR011709 Domain of unknown function DUF1605 A4G23_RS12840 ecc24e0a28f74cbdaf64341323aaa73d 1319 Pfam PF11898 Domain of unknown function (DUF3418) 721 1315 5.1E-233 T 10-11-2016 IPR024590 RNA helicase HrpA, C-terminal A4G23_RS12840 ecc24e0a28f74cbdaf64341323aaa73d 1319 SMART SM00847 461 556 2.6E-39 T 10-11-2016 IPR007502 Helicase-associated domain GO:0004386 A4G23_RS12840 ecc24e0a28f74cbdaf64341323aaa73d 1319 Gene3D G3DSA:3.40.50.300 72 229 7.9E-48 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS12840 ecc24e0a28f74cbdaf64341323aaa73d 1319 SMART SM00382 88 381 2.2E-5 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS12840 ecc24e0a28f74cbdaf64341323aaa73d 1319 SMART SM00487 64 255 3.2E-28 T 10-11-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4G23_RS12840 ecc24e0a28f74cbdaf64341323aaa73d 1319 SMART SM00490 302 401 9.5E-15 T 10-11-2016 IPR001650 Helicase, C-terminal A4G23_RS12840 ecc24e0a28f74cbdaf64341323aaa73d 1319 Pfam PF00271 Helicase conserved C-terminal domain 283 400 6.5E-11 T 10-11-2016 IPR001650 Helicase, C-terminal A4G23_RS12840 ecc24e0a28f74cbdaf64341323aaa73d 1319 SUPERFAMILY SSF52540 70 598 1.3E-113 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS12840 ecc24e0a28f74cbdaf64341323aaa73d 1319 TIGRFAM TIGR01967 DEAH_box_HrpA: RNA helicase HrpA 10 1315 0.0 T 10-11-2016 IPR010222 RNA helicase HrpA GO:0004004 A4G23_RS12840 ecc24e0a28f74cbdaf64341323aaa73d 1319 Gene3D G3DSA:3.40.50.300 270 413 1.0E-11 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS14000 e302aca9d6a5d9f21838033e324c5332 201 SUPERFAMILY SSF48150 20 150 4.71E-14 T 10-11-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A4G23_RS14000 e302aca9d6a5d9f21838033e324c5332 201 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 29 154 1.8E-11 T 10-11-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A4G23_RS14000 e302aca9d6a5d9f21838033e324c5332 201 TIGRFAM TIGR03252 TIGR03252: uncharacterized HhH-GPD family protein 8 196 2.0E-92 T 10-11-2016 IPR017658 Conserved hypothetical protein CHP03252, HhH-GPD A4G23_RS14000 e302aca9d6a5d9f21838033e324c5332 201 Gene3D G3DSA:1.10.340.30 20 140 1.5E-10 T 10-11-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A4G23_RS17285 2db06074c98f5ee61e014994445600ff 239 SUPERFAMILY SSF51621 3 237 1.84E-51 T 10-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A4G23_RS17285 2db06074c98f5ee61e014994445600ff 239 Gene3D G3DSA:3.20.20.60 2 213 7.9E-53 T 10-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A4G23_RS17285 2db06074c98f5ee61e014994445600ff 239 Pfam PF13714 Phosphoenolpyruvate phosphomutase 2 231 1.2E-61 T 10-11-2016 A4G23_RS24125 d4b519d6484e2494c604c81a19363342 138 SMART SM00422 6 75 2.3E-32 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS24125 d4b519d6484e2494c604c81a19363342 138 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 18 31 5.7E-8 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS24125 d4b519d6484e2494c604c81a19363342 138 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 7 18 5.7E-8 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS24125 d4b519d6484e2494c604c81a19363342 138 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 42 62 5.7E-8 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS24125 d4b519d6484e2494c604c81a19363342 138 Gene3D G3DSA:1.10.1660.10 61 132 5.8E-10 T 10-11-2016 A4G23_RS24125 d4b519d6484e2494c604c81a19363342 138 Pfam PF13411 MerR HTH family regulatory protein 6 73 2.0E-18 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS24125 d4b519d6484e2494c604c81a19363342 138 SUPERFAMILY SSF46955 6 124 6.23E-29 T 10-11-2016 IPR009061 Putative DNA-binding domain A4G23_RS24125 d4b519d6484e2494c604c81a19363342 138 Gene3D G3DSA:1.10.1660.10 3 60 1.4E-27 T 10-11-2016 A4G23_RS24125 d4b519d6484e2494c604c81a19363342 138 ProSitePatterns PS00552 MerR-type HTH domain signature. 9 31 - T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS26775 2c72bf3895a2a49e502eb0db5f88e2a5 499 Gene3D G3DSA:1.20.1250.20 262 424 3.4E-21 T 10-11-2016 A4G23_RS26775 2c72bf3895a2a49e502eb0db5f88e2a5 499 Gene3D G3DSA:1.20.1250.20 460 495 3.4E-21 T 10-11-2016 A4G23_RS26775 2c72bf3895a2a49e502eb0db5f88e2a5 499 Gene3D G3DSA:1.20.1250.20 24 197 2.5E-24 T 10-11-2016 A4G23_RS26775 2c72bf3895a2a49e502eb0db5f88e2a5 499 SUPERFAMILY SSF103473 252 424 1.83E-59 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS26775 2c72bf3895a2a49e502eb0db5f88e2a5 499 SUPERFAMILY SSF103473 460 494 1.83E-59 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS26775 2c72bf3895a2a49e502eb0db5f88e2a5 499 SUPERFAMILY SSF103473 10 205 1.83E-59 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS26775 2c72bf3895a2a49e502eb0db5f88e2a5 499 Pfam PF07690 Major Facilitator Superfamily 27 413 3.0E-48 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS26845 a55d6b210b4390878be5bce32b0ed85b 941 SUPERFAMILY SSF52540 694 940 9.29E-68 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS26845 a55d6b210b4390878be5bce32b0ed85b 941 SMART SM00487 475 656 7.1E-27 T 10-11-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4G23_RS26845 a55d6b210b4390878be5bce32b0ed85b 941 Pfam PF00176 SNF2 family N-terminal domain 498 755 9.1E-46 T 10-11-2016 IPR000330 SNF2-related, N-terminal domain GO:0005524 A4G23_RS26845 a55d6b210b4390878be5bce32b0ed85b 941 Pfam PF00271 Helicase conserved C-terminal domain 773 884 4.1E-18 T 10-11-2016 IPR001650 Helicase, C-terminal A4G23_RS26845 a55d6b210b4390878be5bce32b0ed85b 941 Gene3D G3DSA:3.40.50.300 770 922 1.1E-25 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS26845 a55d6b210b4390878be5bce32b0ed85b 941 Gene3D G3DSA:3.40.50.300 474 641 3.3E-19 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS26845 a55d6b210b4390878be5bce32b0ed85b 941 SUPERFAMILY SSF52540 468 687 3.5E-50 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS26845 a55d6b210b4390878be5bce32b0ed85b 941 Pfam PF12419 SNF2 Helicase protein 297 432 9.9E-39 T 10-11-2016 IPR022138 Helicase SWF/SNF-related A4G23_RS26845 a55d6b210b4390878be5bce32b0ed85b 941 SMART SM00490 802 884 3.9E-25 T 10-11-2016 IPR001650 Helicase, C-terminal A4G23_RS10690 1b05467e64196488ad74fd1695ce46e5 542 Pfam PF05223 NTF2-like N-terminal transpeptidase domain 59 165 1.0E-7 T 10-11-2016 IPR007887 NTF2-like N-terminal transpeptidase GO:0046677 A4G23_RS10690 1b05467e64196488ad74fd1695ce46e5 542 Gene3D G3DSA:3.40.710.10 245 541 3.5E-48 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS10690 1b05467e64196488ad74fd1695ce46e5 542 SUPERFAMILY SSF56601 240 541 4.88E-54 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS10690 1b05467e64196488ad74fd1695ce46e5 542 Pfam PF00905 Penicillin binding protein transpeptidase domain 265 539 2.0E-32 T 10-11-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A4G23_RS07115 c1aeb5cc8443f135f3857145a5c8e3e4 490 Pfam PF13456 Reverse transcriptase-like 17 138 1.7E-17 T 10-11-2016 A4G23_RS07115 c1aeb5cc8443f135f3857145a5c8e3e4 490 Gene3D G3DSA:3.30.420.10 10 143 2.1E-21 T 10-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 A4G23_RS07115 c1aeb5cc8443f135f3857145a5c8e3e4 490 SUPERFAMILY SSF53254 288 489 1.3E-53 T 10-11-2016 IPR029033 Histidine phosphatase superfamily A4G23_RS07115 c1aeb5cc8443f135f3857145a5c8e3e4 490 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 290 485 5.0E-59 T 10-11-2016 IPR013078 Histidine phosphatase superfamily, clade-1 A4G23_RS07115 c1aeb5cc8443f135f3857145a5c8e3e4 490 SUPERFAMILY SSF53098 12 137 8.85E-30 T 10-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 A4G23_RS07115 c1aeb5cc8443f135f3857145a5c8e3e4 490 Gene3D G3DSA:3.40.50.1240 288 490 4.8E-57 T 10-11-2016 IPR029033 Histidine phosphatase superfamily A4G23_RS07115 c1aeb5cc8443f135f3857145a5c8e3e4 490 SMART SM00855 289 445 3.8E-17 T 10-11-2016 IPR013078 Histidine phosphatase superfamily, clade-1 A4G23_RS17430 d653e351211b0c69db4a7561410fe1a6 417 SMART SM01209 111 285 0.0062 T 10-11-2016 A4G23_RS17430 d653e351211b0c69db4a7561410fe1a6 417 Gene3D G3DSA:3.30.470.20 111 293 3.5E-15 T 10-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 A4G23_RS17430 d653e351211b0c69db4a7561410fe1a6 417 Pfam PF13535 ATP-grasp domain 150 292 1.5E-10 T 10-11-2016 A4G23_RS17430 d653e351211b0c69db4a7561410fe1a6 417 SUPERFAMILY SSF56059 106 315 1.45E-31 T 10-11-2016 A4G23_RS20990 e30cd7f2756a3238da457923d0e6dffd 96 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 11 88 3.0E-37 T 10-11-2016 A4G23_RS20990 e30cd7f2756a3238da457923d0e6dffd 96 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 10-11-2016 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS20990 e30cd7f2756a3238da457923d0e6dffd 96 Gene3D G3DSA:1.10.287.10 3 89 5.5E-39 T 10-11-2016 IPR009068 S15/NS1, RNA-binding A4G23_RS20990 e30cd7f2756a3238da457923d0e6dffd 96 Pfam PF00312 Ribosomal protein S15 8 88 4.0E-37 T 10-11-2016 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS20990 e30cd7f2756a3238da457923d0e6dffd 96 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 6 89 1.7E-37 T 10-11-2016 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS20990 e30cd7f2756a3238da457923d0e6dffd 96 SMART SM01387 8 88 2.9E-52 T 10-11-2016 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS20990 e30cd7f2756a3238da457923d0e6dffd 96 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 22.235 T 10-11-2016 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS20990 e30cd7f2756a3238da457923d0e6dffd 96 SUPERFAMILY SSF47060 3 89 3.83E-35 T 10-11-2016 IPR009068 S15/NS1, RNA-binding A4G23_RS20690 be96e0ed990a519bcaed1b9f4fc7c142 182 SUPERFAMILY SSF143990 15 181 2.88E-50 T 10-11-2016 A4G23_RS20690 be96e0ed990a519bcaed1b9f4fc7c142 182 TIGRFAM TIGR02464 ribofla_fusion: conserved hypothetical protein 20 180 1.1E-49 T 10-11-2016 IPR012816 NADAR A4G23_RS20690 be96e0ed990a519bcaed1b9f4fc7c142 182 Pfam PF08719 Domain of unknown function (DUF1768) 34 180 2.8E-51 T 10-11-2016 IPR012816 NADAR A4G23_RS23555 404e470b60e0f57020b30a39212ddc68 473 SUPERFAMILY SSF51905 198 243 3.23E-8 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS23555 404e470b60e0f57020b30a39212ddc68 473 SUPERFAMILY SSF51905 287 394 3.23E-8 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS23555 404e470b60e0f57020b30a39212ddc68 473 SUPERFAMILY SSF51905 11 263 1.24E-16 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS23555 404e470b60e0f57020b30a39212ddc68 473 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 13 355 6.2E-110 T 10-11-2016 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase A4G23_RS23555 404e470b60e0f57020b30a39212ddc68 473 Gene3D G3DSA:3.50.50.60 95 213 8.1E-10 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS23555 404e470b60e0f57020b30a39212ddc68 473 Gene3D G3DSA:3.50.50.60 18 94 5.6E-8 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS23555 404e470b60e0f57020b30a39212ddc68 473 Gene3D G3DSA:3.50.50.60 214 374 5.6E-8 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS00110 1e266d5f22d78c31d70fa1a1e2ba95c5 398 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 1 255 1.8E-50 T 10-11-2016 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 A4G23_RS00110 1e266d5f22d78c31d70fa1a1e2ba95c5 398 Gene3D G3DSA:3.60.21.10 1 276 5.7E-72 T 10-11-2016 IPR029052 Metallo-dependent phosphatase-like A4G23_RS00110 1e266d5f22d78c31d70fa1a1e2ba95c5 398 Pfam PF00149 Calcineurin-like phosphoesterase 1 91 4.1E-12 T 10-11-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 A4G23_RS00110 1e266d5f22d78c31d70fa1a1e2ba95c5 398 SUPERFAMILY SSF56300 1 321 2.13E-56 T 10-11-2016 IPR029052 Metallo-dependent phosphatase-like A4G23_RS00110 1e266d5f22d78c31d70fa1a1e2ba95c5 398 Pfam PF12320 Type 5 capsule protein repressor C-terminal domain 278 366 2.0E-7 T 10-11-2016 IPR026843 Nuclease SbcCD subunit D, C-terminal domain A4G23_RS27330 1e266d5f22d78c31d70fa1a1e2ba95c5 398 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 1 255 1.8E-50 T 10-11-2016 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 A4G23_RS27330 1e266d5f22d78c31d70fa1a1e2ba95c5 398 Gene3D G3DSA:3.60.21.10 1 276 5.7E-72 T 10-11-2016 IPR029052 Metallo-dependent phosphatase-like A4G23_RS27330 1e266d5f22d78c31d70fa1a1e2ba95c5 398 Pfam PF00149 Calcineurin-like phosphoesterase 1 91 4.1E-12 T 10-11-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 A4G23_RS27330 1e266d5f22d78c31d70fa1a1e2ba95c5 398 SUPERFAMILY SSF56300 1 321 2.13E-56 T 10-11-2016 IPR029052 Metallo-dependent phosphatase-like A4G23_RS27330 1e266d5f22d78c31d70fa1a1e2ba95c5 398 Pfam PF12320 Type 5 capsule protein repressor C-terminal domain 278 366 2.0E-7 T 10-11-2016 IPR026843 Nuclease SbcCD subunit D, C-terminal domain A4G23_RS23545 694b9ddc316b09c13c5c3dfa4a8a9b5b 182 SMART SM01006 21 68 3.7E-17 T 10-11-2016 IPR019432 Siderophore biosynthesis protein, conserved domain A4G23_RS23545 694b9ddc316b09c13c5c3dfa4a8a9b5b 182 Pfam PF13523 Acetyltransferase (GNAT) domain 24 169 1.5E-50 T 10-11-2016 A4G23_RS23545 694b9ddc316b09c13c5c3dfa4a8a9b5b 182 SUPERFAMILY SSF55729 17 181 6.05E-49 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS23545 694b9ddc316b09c13c5c3dfa4a8a9b5b 182 Gene3D G3DSA:3.40.630.30 17 181 3.5E-56 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS16370 2704a88cf8052f6ec9eb073dac2e51e4 1161 Pfam PF04563 RNA polymerase beta subunit 40 409 1.1E-21 T 10-11-2016 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4G23_RS16370 2704a88cf8052f6ec9eb073dac2e51e4 1161 Gene3D G3DSA:2.30.150.10 503 568 5.1E-27 T 10-11-2016 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4G23_RS16370 2704a88cf8052f6ec9eb073dac2e51e4 1161 Gene3D G3DSA:2.40.50.100 627 697 2.7E-26 T 10-11-2016 A4G23_RS16370 2704a88cf8052f6ec9eb073dac2e51e4 1161 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 236 842 0.0 T 10-11-2016 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4G23_RS16370 2704a88cf8052f6ec9eb073dac2e51e4 1161 Pfam PF04561 RNA polymerase Rpb2, domain 2 169 365 1.8E-29 T 10-11-2016 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4G23_RS16370 2704a88cf8052f6ec9eb073dac2e51e4 1161 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 23 1125 12.363 T 10-11-2016 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4G23_RS16370 2704a88cf8052f6ec9eb073dac2e51e4 1161 Pfam PF04560 RNA polymerase Rpb2, domain 7 1049 1123 4.0E-27 T 10-11-2016 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4G23_RS16370 2704a88cf8052f6ec9eb073dac2e51e4 1161 Pfam PF04565 RNA polymerase Rpb2, domain 3 424 492 1.8E-28 T 10-11-2016 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4G23_RS16370 2704a88cf8052f6ec9eb073dac2e51e4 1161 Gene3D G3DSA:3.90.1110.10 171 340 5.9E-69 T 10-11-2016 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4G23_RS16370 2704a88cf8052f6ec9eb073dac2e51e4 1161 Pfam PF00562 RNA polymerase Rpb2, domain 6 630 1047 8.9E-155 T 10-11-2016 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4G23_RS16370 2704a88cf8052f6ec9eb073dac2e51e4 1161 Gene3D G3DSA:3.90.1100.10 29 169 1.9E-145 T 10-11-2016 A4G23_RS16370 2704a88cf8052f6ec9eb073dac2e51e4 1161 Gene3D G3DSA:3.90.1100.10 571 625 1.9E-145 T 10-11-2016 A4G23_RS16370 2704a88cf8052f6ec9eb073dac2e51e4 1161 Gene3D G3DSA:3.90.1100.10 354 502 1.9E-145 T 10-11-2016 A4G23_RS16370 2704a88cf8052f6ec9eb073dac2e51e4 1161 SUPERFAMILY SSF64484 22 1133 0.0 T 10-11-2016 A4G23_RS16370 2704a88cf8052f6ec9eb073dac2e51e4 1161 Gene3D G3DSA:2.40.50.150 734 864 1.1E-56 T 10-11-2016 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4G23_RS16370 2704a88cf8052f6ec9eb073dac2e51e4 1161 Gene3D G3DSA:2.40.270.10 865 1025 1.3E-75 T 10-11-2016 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4G23_RS16370 2704a88cf8052f6ec9eb073dac2e51e4 1161 Gene3D G3DSA:2.40.270.10 698 725 1.3E-75 T 10-11-2016 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4G23_RS16370 2704a88cf8052f6ec9eb073dac2e51e4 1161 ProSitePatterns PS01166 RNA polymerases beta chain signature. 868 880 - T 10-11-2016 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4G23_RS16370 2704a88cf8052f6ec9eb073dac2e51e4 1161 Pfam PF10385 RNA polymerase beta subunit external 1 domain 502 568 1.3E-24 T 10-11-2016 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4G23_RS17855 934a0d412c024040c3a52d277d022785 287 Gene3D G3DSA:3.30.930.10 33 217 4.3E-52 T 10-11-2016 A4G23_RS17855 934a0d412c024040c3a52d277d022785 287 Pfam PF03099 Biotin/lipoate A/B protein ligase family 50 169 7.2E-12 T 10-11-2016 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 A4G23_RS17855 934a0d412c024040c3a52d277d022785 287 SUPERFAMILY SSF55681 31 217 1.14E-44 T 10-11-2016 A4G23_RS17855 934a0d412c024040c3a52d277d022785 287 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 44 282 4.2E-41 T 10-11-2016 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4G23_RS17855 934a0d412c024040c3a52d277d022785 287 Gene3D G3DSA:2.30.30.100 236 286 9.0E-5 T 10-11-2016 A4G23_RS17855 934a0d412c024040c3a52d277d022785 287 Pfam PF02237 Biotin protein ligase C terminal domain 235 282 5.5E-9 T 10-11-2016 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4G23_RS00295 850136d5e70f61d1c0b39d009f1d6dad 292 Pfam PF00196 Bacterial regulatory proteins, luxR family 232 281 1.4E-10 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS00295 850136d5e70f61d1c0b39d009f1d6dad 292 Gene3D G3DSA:1.10.10.10 224 290 2.5E-16 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS00295 850136d5e70f61d1c0b39d009f1d6dad 292 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 245 261 7.9E-7 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS00295 850136d5e70f61d1c0b39d009f1d6dad 292 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 261 273 7.9E-7 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS00295 850136d5e70f61d1c0b39d009f1d6dad 292 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 231 245 7.9E-7 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS00295 850136d5e70f61d1c0b39d009f1d6dad 292 SMART SM00421 228 285 7.1E-12 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS00295 850136d5e70f61d1c0b39d009f1d6dad 292 SUPERFAMILY SSF46894 227 291 5.44E-14 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS04765 a82345f179bc81bcf27e52e05e833979 396 SUPERFAMILY SSF47203 243 392 6.77E-41 T 10-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4G23_RS04765 a82345f179bc81bcf27e52e05e833979 396 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 24 136 8.6E-29 T 10-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 A4G23_RS04765 a82345f179bc81bcf27e52e05e833979 396 Gene3D G3DSA:2.40.110.10 139 230 6.5E-37 T 10-11-2016 A4G23_RS04765 a82345f179bc81bcf27e52e05e833979 396 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 243 389 7.0E-30 T 10-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4G23_RS04765 a82345f179bc81bcf27e52e05e833979 396 Gene3D G3DSA:1.20.140.10 231 392 1.9E-41 T 10-11-2016 A4G23_RS04765 a82345f179bc81bcf27e52e05e833979 396 SUPERFAMILY SSF56645 10 241 2.62E-74 T 10-11-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 A4G23_RS04765 a82345f179bc81bcf27e52e05e833979 396 Gene3D G3DSA:1.10.540.10 10 138 1.4E-36 T 10-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 A4G23_RS04765 a82345f179bc81bcf27e52e05e833979 396 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 140 230 2.5E-23 T 10-11-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 A4G23_RS06730 692772680ce35678f3fc6c97d8205713 164 Gene3D G3DSA:3.40.630.30 6 162 6.9E-31 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS06730 692772680ce35678f3fc6c97d8205713 164 Pfam PF00583 Acetyltransferase (GNAT) family 61 136 6.0E-16 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS06730 692772680ce35678f3fc6c97d8205713 164 SUPERFAMILY SSF55729 6 162 1.2E-32 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS25505 a8701243d9634076db1965f945fb4bed 356 Pfam PF00107 Zinc-binding dehydrogenase 178 289 7.1E-26 T 10-11-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A4G23_RS25505 a8701243d9634076db1965f945fb4bed 356 SMART SM00829 10 344 5.4E-5 T 10-11-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A4G23_RS25505 a8701243d9634076db1965f945fb4bed 356 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 128 5.8E-29 T 10-11-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A4G23_RS25505 a8701243d9634076db1965f945fb4bed 356 SUPERFAMILY SSF51735 140 308 3.66E-41 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS25505 a8701243d9634076db1965f945fb4bed 356 SUPERFAMILY SSF50129 1 166 7.3E-54 T 10-11-2016 IPR011032 GroES-like A4G23_RS25505 a8701243d9634076db1965f945fb4bed 356 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 10-11-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 A4G23_RS25505 a8701243d9634076db1965f945fb4bed 356 Gene3D G3DSA:3.90.180.10 1 172 2.1E-53 T 10-11-2016 IPR011032 GroES-like A4G23_RS25505 a8701243d9634076db1965f945fb4bed 356 Gene3D G3DSA:3.40.50.720 173 287 4.2E-38 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS04385 a25d102ef0285643be63ea9a182c939b 536 SUPERFAMILY SSF51905 419 460 5.09E-33 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS04385 a25d102ef0285643be63ea9a182c939b 536 SUPERFAMILY SSF51905 33 260 5.09E-33 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS04385 a25d102ef0285643be63ea9a182c939b 536 Pfam PF01266 FAD dependent oxidoreductase 35 389 2.8E-45 T 10-11-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A4G23_RS04385 a25d102ef0285643be63ea9a182c939b 536 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 47 57 2.0E-20 T 10-11-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 A4G23_RS04385 a25d102ef0285643be63ea9a182c939b 536 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 378 390 2.0E-20 T 10-11-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 A4G23_RS04385 a25d102ef0285643be63ea9a182c939b 536 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 349 355 2.0E-20 T 10-11-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 A4G23_RS04385 a25d102ef0285643be63ea9a182c939b 536 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 34 46 2.0E-20 T 10-11-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 A4G23_RS04385 a25d102ef0285643be63ea9a182c939b 536 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 109 121 2.0E-20 T 10-11-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 A4G23_RS04385 a25d102ef0285643be63ea9a182c939b 536 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 63 75 2.0E-20 T 10-11-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 A4G23_RS04385 a25d102ef0285643be63ea9a182c939b 536 Gene3D G3DSA:3.50.50.60 33 275 6.6E-42 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS04385 a25d102ef0285643be63ea9a182c939b 536 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 421 533 6.7E-13 T 10-11-2016 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 A4G23_RS23715 9cb5a3fe603d96ddcbaac7a8bea92688 914 Pfam PF00122 E1-E2 ATPase 82 319 3.0E-66 T 10-11-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 A4G23_RS23715 9cb5a3fe603d96ddcbaac7a8bea92688 914 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 545 556 1.9E-36 T 10-11-2016 A4G23_RS23715 9cb5a3fe603d96ddcbaac7a8bea92688 914 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 668 680 1.9E-36 T 10-11-2016 A4G23_RS23715 9cb5a3fe603d96ddcbaac7a8bea92688 914 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 328 342 1.9E-36 T 10-11-2016 A4G23_RS23715 9cb5a3fe603d96ddcbaac7a8bea92688 914 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 644 663 1.9E-36 T 10-11-2016 A4G23_RS23715 9cb5a3fe603d96ddcbaac7a8bea92688 914 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 567 577 1.9E-36 T 10-11-2016 A4G23_RS23715 9cb5a3fe603d96ddcbaac7a8bea92688 914 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 162 176 1.9E-36 T 10-11-2016 A4G23_RS23715 9cb5a3fe603d96ddcbaac7a8bea92688 914 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 218 349 1.3E-23 T 10-11-2016 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A4G23_RS23715 9cb5a3fe603d96ddcbaac7a8bea92688 914 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 615 733 5.3E-34 T 10-11-2016 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A4G23_RS23715 9cb5a3fe603d96ddcbaac7a8bea92688 914 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 83 179 3.8E-19 T 10-11-2016 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A4G23_RS23715 9cb5a3fe603d96ddcbaac7a8bea92688 914 SUPERFAMILY SSF56784 487 748 5.45E-57 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS23715 9cb5a3fe603d96ddcbaac7a8bea92688 914 SUPERFAMILY SSF56784 326 346 5.45E-57 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS23715 9cb5a3fe603d96ddcbaac7a8bea92688 914 PRINTS PR00121 Sodium/potassium-transporting ATPase signature 321 342 5.2E-16 T 10-11-2016 A4G23_RS23715 9cb5a3fe603d96ddcbaac7a8bea92688 914 PRINTS PR00121 Sodium/potassium-transporting ATPase signature 716 737 5.2E-16 T 10-11-2016 A4G23_RS23715 9cb5a3fe603d96ddcbaac7a8bea92688 914 PRINTS PR00121 Sodium/potassium-transporting ATPase signature 78 98 5.2E-16 T 10-11-2016 A4G23_RS23715 9cb5a3fe603d96ddcbaac7a8bea92688 914 PRINTS PR00121 Sodium/potassium-transporting ATPase signature 457 475 5.2E-16 T 10-11-2016 A4G23_RS23715 9cb5a3fe603d96ddcbaac7a8bea92688 914 SMART SM00831 3 77 2.5E-23 T 10-11-2016 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 A4G23_RS23715 9cb5a3fe603d96ddcbaac7a8bea92688 914 SUPERFAMILY SSF81665 694 899 6.41E-119 T 10-11-2016 A4G23_RS23715 9cb5a3fe603d96ddcbaac7a8bea92688 914 SUPERFAMILY SSF81665 229 322 6.41E-119 T 10-11-2016 A4G23_RS23715 9cb5a3fe603d96ddcbaac7a8bea92688 914 SUPERFAMILY SSF81665 5 115 6.41E-119 T 10-11-2016 A4G23_RS23715 9cb5a3fe603d96ddcbaac7a8bea92688 914 Gene3D G3DSA:2.70.150.10 16 55 1.2E-36 T 10-11-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 A4G23_RS23715 9cb5a3fe603d96ddcbaac7a8bea92688 914 Gene3D G3DSA:2.70.150.10 110 227 1.2E-36 T 10-11-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 A4G23_RS23715 9cb5a3fe603d96ddcbaac7a8bea92688 914 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 330 336 - T 10-11-2016 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 A4G23_RS23715 9cb5a3fe603d96ddcbaac7a8bea92688 914 Gene3D G3DSA:3.40.1110.10 318 552 3.4E-53 T 10-11-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A4G23_RS23715 9cb5a3fe603d96ddcbaac7a8bea92688 914 Pfam PF13246 Cation transport ATPase (P-type) 390 473 2.9E-19 T 10-11-2016 A4G23_RS23715 9cb5a3fe603d96ddcbaac7a8bea92688 914 SUPERFAMILY SSF81660 335 549 5.23E-47 T 10-11-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A4G23_RS23715 9cb5a3fe603d96ddcbaac7a8bea92688 914 Pfam PF00690 Cation transporter/ATPase, N-terminus 8 72 1.2E-14 T 10-11-2016 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 A4G23_RS23715 9cb5a3fe603d96ddcbaac7a8bea92688 914 Pfam PF00689 Cation transporting ATPase, C-terminus 728 897 3.3E-46 T 10-11-2016 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 A4G23_RS23715 9cb5a3fe603d96ddcbaac7a8bea92688 914 Gene3D G3DSA:1.20.1110.10 613 898 1.3E-118 T 10-11-2016 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A4G23_RS23715 9cb5a3fe603d96ddcbaac7a8bea92688 914 Gene3D G3DSA:1.20.1110.10 56 109 1.3E-118 T 10-11-2016 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A4G23_RS23715 9cb5a3fe603d96ddcbaac7a8bea92688 914 SUPERFAMILY SSF81653 115 226 2.09E-27 T 10-11-2016 A4G23_RS07080 bf1f27bce2f3504cf859c5098616673f 142 Gene3D G3DSA:3.30.565.10 48 141 2.0E-5 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS07080 bf1f27bce2f3504cf859c5098616673f 142 SUPERFAMILY SSF55874 36 141 2.05E-8 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS07080 bf1f27bce2f3504cf859c5098616673f 142 Pfam PF13581 Histidine kinase-like ATPase domain 15 125 2.8E-9 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS05385 fe34671db4395cd40ab4cb4771b0ee94 509 Gene3D G3DSA:3.40.605.10 8 247 1.3E-38 T 10-11-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A4G23_RS05385 fe34671db4395cd40ab4cb4771b0ee94 509 Pfam PF00171 Aldehyde dehydrogenase family 8 414 1.8E-40 T 10-11-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A4G23_RS05385 fe34671db4395cd40ab4cb4771b0ee94 509 SUPERFAMILY SSF53720 8 504 2.88E-81 T 10-11-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A4G23_RS05385 fe34671db4395cd40ab4cb4771b0ee94 509 Gene3D G3DSA:3.40.309.10 248 441 3.5E-48 T 10-11-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 A4G23_RS27250 708fd71a9c658ba193f9638be8a2fea4 402 Gene3D G3DSA:3.90.1150.10 258 389 3.0E-39 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS27250 708fd71a9c658ba193f9638be8a2fea4 402 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 235 248 - T 10-11-2016 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 A4G23_RS27250 708fd71a9c658ba193f9638be8a2fea4 402 Pfam PF00155 Aminotransferase class I and II 32 383 4.2E-62 T 10-11-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4G23_RS27250 708fd71a9c658ba193f9638be8a2fea4 402 Gene3D G3DSA:3.40.640.10 47 257 3.6E-70 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS27250 708fd71a9c658ba193f9638be8a2fea4 402 SUPERFAMILY SSF53383 6 389 4.98E-110 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS25320 4d94a5d4a3e1cd7fbbc96aa8fc4c79eb 666 Gene3D G3DSA:3.40.50.300 498 610 1.6E-67 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS25320 4d94a5d4a3e1cd7fbbc96aa8fc4c79eb 666 Gene3D G3DSA:3.40.50.300 339 455 1.6E-67 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS25320 4d94a5d4a3e1cd7fbbc96aa8fc4c79eb 666 SUPERFAMILY SSF90123 8 324 7.06E-65 T 10-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A4G23_RS25320 4d94a5d4a3e1cd7fbbc96aa8fc4c79eb 666 Pfam PF00664 ABC transporter transmembrane region 27 291 5.0E-36 T 10-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A4G23_RS25320 4d94a5d4a3e1cd7fbbc96aa8fc4c79eb 666 Gene3D G3DSA:1.20.1560.10 8 325 1.1E-66 T 10-11-2016 A4G23_RS25320 4d94a5d4a3e1cd7fbbc96aa8fc4c79eb 666 SMART SM00382 365 594 5.3E-13 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS25320 4d94a5d4a3e1cd7fbbc96aa8fc4c79eb 666 ProSitePatterns PS00211 ABC transporters family signature. 520 534 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS25320 4d94a5d4a3e1cd7fbbc96aa8fc4c79eb 666 SUPERFAMILY SSF52540 327 431 2.59E-59 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS25320 4d94a5d4a3e1cd7fbbc96aa8fc4c79eb 666 SUPERFAMILY SSF52540 489 613 2.59E-59 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS25320 4d94a5d4a3e1cd7fbbc96aa8fc4c79eb 666 Pfam PF00005 ABC transporter 356 547 8.0E-27 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS21315 5db70de162c9a6fa1efc5b1e24774728 536 SUPERFAMILY SSF52540 5 234 4.87E-46 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS21315 5db70de162c9a6fa1efc5b1e24774728 536 ProSitePatterns PS00211 ABC transporters family signature. 460 474 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS21315 5db70de162c9a6fa1efc5b1e24774728 536 Gene3D G3DSA:3.40.50.300 4 101 9.6E-47 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS21315 5db70de162c9a6fa1efc5b1e24774728 536 Gene3D G3DSA:3.40.50.300 134 274 9.6E-47 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS21315 5db70de162c9a6fa1efc5b1e24774728 536 Pfam PF00005 ABC transporter 365 488 6.1E-19 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS21315 5db70de162c9a6fa1efc5b1e24774728 536 Pfam PF00005 ABC transporter 20 188 1.9E-28 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS21315 5db70de162c9a6fa1efc5b1e24774728 536 SMART SM00382 369 533 8.3E-11 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS21315 5db70de162c9a6fa1efc5b1e24774728 536 SMART SM00382 29 233 1.8E-13 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS21315 5db70de162c9a6fa1efc5b1e24774728 536 SUPERFAMILY SSF52540 364 534 7.47E-34 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS21315 5db70de162c9a6fa1efc5b1e24774728 536 Gene3D G3DSA:3.40.50.300 365 532 8.4E-30 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS21315 5db70de162c9a6fa1efc5b1e24774728 536 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS17260 ed17e1447edbff67ec52ce423cab0dda 502 Gene3D G3DSA:3.40.309.10 268 454 2.2E-64 T 10-11-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 A4G23_RS17260 ed17e1447edbff67ec52ce423cab0dda 502 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 255 262 - T 10-11-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 A4G23_RS17260 ed17e1447edbff67ec52ce423cab0dda 502 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 288 299 - T 10-11-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 A4G23_RS17260 ed17e1447edbff67ec52ce423cab0dda 502 Pfam PF00171 Aldehyde dehydrogenase family 15 488 4.4E-163 T 10-11-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A4G23_RS17260 ed17e1447edbff67ec52ce423cab0dda 502 SUPERFAMILY SSF53720 5 493 1.07E-159 T 10-11-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A4G23_RS17260 ed17e1447edbff67ec52ce423cab0dda 502 Gene3D G3DSA:3.40.605.10 7 267 1.2E-89 T 10-11-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A4G23_RS26595 cea7a4a04d7244101851a98852b6aa14 193 SUPERFAMILY SSF52821 9 112 6.94E-30 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS26595 cea7a4a04d7244101851a98852b6aa14 193 Pfam PF11127 Protein of unknown function (DUF2892) 118 176 6.9E-9 T 10-11-2016 IPR021309 Protein of unknown function DUF2892 A4G23_RS26595 cea7a4a04d7244101851a98852b6aa14 193 SMART SM00450 11 108 1.9E-24 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS26595 cea7a4a04d7244101851a98852b6aa14 193 Pfam PF00581 Rhodanese-like domain 12 104 6.8E-17 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS26595 cea7a4a04d7244101851a98852b6aa14 193 Gene3D G3DSA:3.40.250.10 6 109 4.9E-27 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS26950 57a953844149fac9c0f4e77f877f56c2 378 SUPERFAMILY SSF53901 2 190 1.39E-47 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS26950 57a953844149fac9c0f4e77f877f56c2 378 Pfam PF08392 FAE1/Type III polyketide synthase-like protein 7 190 1.0E-17 T 10-11-2016 IPR013601 FAE1/Type III polyketide synthase-like protein GO:0006633|GO:0016020|GO:0016747 KEGG: 00062+2.3.1.199|KEGG: 00650+2.3.1.19|MetaCyc: PWY-5080|MetaCyc: PWY-5972|MetaCyc: PWY-6433|MetaCyc: PWY-6598|MetaCyc: PWY-7036|MetaCyc: PWY-7601|MetaCyc: PWY-7602|MetaCyc: PWY-7619|MetaCyc: PWY-7724|MetaCyc: PWY-7725 A4G23_RS26950 57a953844149fac9c0f4e77f877f56c2 378 PIRSF PIRSF000451 1 341 2.2E-111 T 10-11-2016 IPR011141 Polyketide synthase, type III GO:0009058|GO:0016747 A4G23_RS26950 57a953844149fac9c0f4e77f877f56c2 378 SUPERFAMILY SSF53901 198 338 1.07E-35 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS26950 57a953844149fac9c0f4e77f877f56c2 378 Gene3D G3DSA:3.40.47.10 2 192 8.9E-56 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS26950 57a953844149fac9c0f4e77f877f56c2 378 Gene3D G3DSA:3.40.47.10 199 338 9.6E-33 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS26950 57a953844149fac9c0f4e77f877f56c2 378 Pfam PF02797 Chalcone and stilbene synthases, C-terminal domain 206 333 1.5E-19 T 10-11-2016 IPR012328 Chalcone/stilbene synthase, C-terminal A4G23_RS12965 cf714f24fa06ac0234b5bc5a8088672e 417 SUPERFAMILY SSF52440 2 101 1.37E-29 T 10-11-2016 IPR016185 Pre-ATP-grasp domain A4G23_RS12965 cf714f24fa06ac0234b5bc5a8088672e 417 SMART SM01209 101 283 9.9E-113 T 10-11-2016 A4G23_RS12965 cf714f24fa06ac0234b5bc5a8088672e 417 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 414 40.024 T 10-11-2016 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A4G23_RS12965 cf714f24fa06ac0234b5bc5a8088672e 417 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 319 411 9.2E-28 T 10-11-2016 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A4G23_RS12965 cf714f24fa06ac0234b5bc5a8088672e 417 Gene3D G3DSA:3.40.50.20 2 93 4.5E-32 T 10-11-2016 IPR016185 Pre-ATP-grasp domain A4G23_RS12965 cf714f24fa06ac0234b5bc5a8088672e 417 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 2 100 1.8E-28 T 10-11-2016 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A4G23_RS12965 cf714f24fa06ac0234b5bc5a8088672e 417 Gene3D G3DSA:3.30.470.20 179 315 1.2E-55 T 10-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 A4G23_RS12965 cf714f24fa06ac0234b5bc5a8088672e 417 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 277 284 - T 10-11-2016 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A4G23_RS12965 cf714f24fa06ac0234b5bc5a8088672e 417 SUPERFAMILY SSF56059 102 306 4.38E-54 T 10-11-2016 A4G23_RS12965 cf714f24fa06ac0234b5bc5a8088672e 417 SUPERFAMILY SSF51246 316 412 5.76E-26 T 10-11-2016 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4G23_RS12965 cf714f24fa06ac0234b5bc5a8088672e 417 Gene3D G3DSA:3.30.1490.20 122 178 3.5E-16 T 10-11-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A4G23_RS12965 cf714f24fa06ac0234b5bc5a8088672e 417 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 283 5.0E-65 T 10-11-2016 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A4G23_RS12965 cf714f24fa06ac0234b5bc5a8088672e 417 Gene3D G3DSA:3.90.600.10 318 412 5.1E-33 T 10-11-2016 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A4G23_RS12965 cf714f24fa06ac0234b5bc5a8088672e 417 SMART SM01210 318 414 4.2E-45 T 10-11-2016 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A4G23_RS12965 cf714f24fa06ac0234b5bc5a8088672e 417 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 2 412 1.5E-143 T 10-11-2016 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A4G23_RS12020 5771cc6aa4c72201996594388a7b3831 280 Pfam PF02358 Trehalose-phosphatase 32 245 1.4E-27 T 10-11-2016 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 A4G23_RS12020 5771cc6aa4c72201996594388a7b3831 280 SUPERFAMILY SSF56784 30 275 1.0E-32 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS12020 5771cc6aa4c72201996594388a7b3831 280 TIGRFAM TIGR00685 T6PP: trehalose-phosphatase 30 275 7.7E-34 T 10-11-2016 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 A4G23_RS12020 5771cc6aa4c72201996594388a7b3831 280 Gene3D G3DSA:3.40.50.1000 188 277 7.5E-34 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS12020 5771cc6aa4c72201996594388a7b3831 280 Gene3D G3DSA:3.40.50.1000 30 108 7.5E-34 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS13145 9dab8a200855a9bb494faf5b888b66db 415 Gene3D G3DSA:1.20.1250.20 9 182 3.5E-26 T 10-11-2016 A4G23_RS13145 9dab8a200855a9bb494faf5b888b66db 415 Pfam PF07690 Major Facilitator Superfamily 11 243 5.3E-22 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS13145 9dab8a200855a9bb494faf5b888b66db 415 SUPERFAMILY SSF103473 6 401 6.93E-53 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS13145 9dab8a200855a9bb494faf5b888b66db 415 Gene3D G3DSA:1.20.1250.20 228 402 1.4E-11 T 10-11-2016 A4G23_RS17800 a667cc0aa00b49977189868b73e70916 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 318 325 2.7E-53 T 10-11-2016 A4G23_RS17800 a667cc0aa00b49977189868b73e70916 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 419 434 2.7E-53 T 10-11-2016 A4G23_RS17800 a667cc0aa00b49977189868b73e70916 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 354 375 2.7E-53 T 10-11-2016 A4G23_RS17800 a667cc0aa00b49977189868b73e70916 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 35 50 2.7E-53 T 10-11-2016 A4G23_RS17800 a667cc0aa00b49977189868b73e70916 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 154 163 2.7E-53 T 10-11-2016 A4G23_RS17800 a667cc0aa00b49977189868b73e70916 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 275 289 2.7E-53 T 10-11-2016 A4G23_RS17800 a667cc0aa00b49977189868b73e70916 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 2.7E-53 T 10-11-2016 A4G23_RS17800 a667cc0aa00b49977189868b73e70916 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 190 215 2.7E-53 T 10-11-2016 A4G23_RS17800 a667cc0aa00b49977189868b73e70916 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 441 461 2.7E-53 T 10-11-2016 A4G23_RS17800 a667cc0aa00b49977189868b73e70916 479 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 151 169 9.9E-34 T 10-11-2016 A4G23_RS17800 a667cc0aa00b49977189868b73e70916 479 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 9.9E-34 T 10-11-2016 A4G23_RS17800 a667cc0aa00b49977189868b73e70916 479 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 274 290 9.9E-34 T 10-11-2016 A4G23_RS17800 a667cc0aa00b49977189868b73e70916 479 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 190 208 9.9E-34 T 10-11-2016 A4G23_RS17800 a667cc0aa00b49977189868b73e70916 479 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 303 325 9.9E-34 T 10-11-2016 A4G23_RS17800 a667cc0aa00b49977189868b73e70916 479 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 338 7.3E-56 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS17800 a667cc0aa00b49977189868b73e70916 479 Gene3D G3DSA:3.50.50.60 3 154 3.1E-27 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS17800 a667cc0aa00b49977189868b73e70916 479 SUPERFAMILY SSF55424 354 472 3.09E-30 T 10-11-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 A4G23_RS17800 a667cc0aa00b49977189868b73e70916 479 Gene3D G3DSA:3.30.390.30 352 471 2.7E-33 T 10-11-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A4G23_RS17800 a667cc0aa00b49977189868b73e70916 479 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 359 465 1.1E-25 T 10-11-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A4G23_RS17800 a667cc0aa00b49977189868b73e70916 479 Gene3D G3DSA:3.50.50.60 155 346 3.9E-46 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS17800 a667cc0aa00b49977189868b73e70916 479 PIRSF PIRSF000350 1 472 9.3E-75 T 10-11-2016 A4G23_RS17800 a667cc0aa00b49977189868b73e70916 479 SUPERFAMILY SSF51905 3 90 5.47E-46 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS17800 a667cc0aa00b49977189868b73e70916 479 SUPERFAMILY SSF51905 139 347 5.47E-46 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS10210 7279c72ec710f7826a372cbf9e1bf806 299 SUPERFAMILY SSF88659 214 295 1.57E-15 T 10-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS10210 7279c72ec710f7826a372cbf9e1bf806 299 SUPERFAMILY SSF88946 51 147 1.57E-29 T 10-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS10210 7279c72ec710f7826a372cbf9e1bf806 299 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 75 294 3.3E-32 T 10-11-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS10210 7279c72ec710f7826a372cbf9e1bf806 299 SUPERFAMILY SSF88659 151 226 4.36E-16 T 10-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS10210 7279c72ec710f7826a372cbf9e1bf806 299 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 102 115 - T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS10210 7279c72ec710f7826a372cbf9e1bf806 299 Pfam PF04539 Sigma-70 region 3 157 224 2.4E-16 T 10-11-2016 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS10210 7279c72ec710f7826a372cbf9e1bf806 299 Gene3D G3DSA:1.10.10.10 241 295 2.8E-10 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS10210 7279c72ec710f7826a372cbf9e1bf806 299 Pfam PF04542 Sigma-70 region 2 78 147 3.2E-15 T 10-11-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS10210 7279c72ec710f7826a372cbf9e1bf806 299 Pfam PF04545 Sigma-70, region 4 245 293 7.0E-18 T 10-11-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS10210 7279c72ec710f7826a372cbf9e1bf806 299 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 72 295 8.8E-92 T 10-11-2016 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS10210 7279c72ec710f7826a372cbf9e1bf806 299 PRINTS PR00046 Major sigma-70 factor signature 102 115 2.9E-11 T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS10210 7279c72ec710f7826a372cbf9e1bf806 299 PRINTS PR00046 Major sigma-70 factor signature 265 280 2.9E-11 T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS10210 7279c72ec710f7826a372cbf9e1bf806 299 PRINTS PR00046 Major sigma-70 factor signature 248 260 2.9E-11 T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS10210 7279c72ec710f7826a372cbf9e1bf806 299 PRINTS PR00046 Major sigma-70 factor signature 280 291 2.9E-11 T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS10210 7279c72ec710f7826a372cbf9e1bf806 299 Gene3D G3DSA:1.10.10.10 146 201 1.7E-24 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS10210 7279c72ec710f7826a372cbf9e1bf806 299 Gene3D G3DSA:1.10.601.10 63 145 2.9E-23 T 10-11-2016 A4G23_RS11900 07d28d40101ffbd6ac1c726cd0184eeb 801 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 315 329 1.0E-21 T 10-11-2016 A4G23_RS11900 07d28d40101ffbd6ac1c726cd0184eeb 801 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 477 487 1.0E-21 T 10-11-2016 A4G23_RS11900 07d28d40101ffbd6ac1c726cd0184eeb 801 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 555 574 1.0E-21 T 10-11-2016 A4G23_RS11900 07d28d40101ffbd6ac1c726cd0184eeb 801 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 164 178 1.0E-21 T 10-11-2016 A4G23_RS11900 07d28d40101ffbd6ac1c726cd0184eeb 801 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 578 590 1.0E-21 T 10-11-2016 A4G23_RS11900 07d28d40101ffbd6ac1c726cd0184eeb 801 SUPERFAMILY SSF81653 119 211 1.12E-21 T 10-11-2016 A4G23_RS11900 07d28d40101ffbd6ac1c726cd0184eeb 801 Pfam PF00702 haloacid dehalogenase-like hydrolase 311 569 5.6E-16 T 10-11-2016 A4G23_RS11900 07d28d40101ffbd6ac1c726cd0184eeb 801 Gene3D G3DSA:2.70.150.10 112 212 1.6E-24 T 10-11-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 A4G23_RS11900 07d28d40101ffbd6ac1c726cd0184eeb 801 Gene3D G3DSA:2.70.150.10 25 60 1.6E-24 T 10-11-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 A4G23_RS11900 07d28d40101ffbd6ac1c726cd0184eeb 801 SUPERFAMILY SSF56784 313 333 1.9E-33 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS11900 07d28d40101ffbd6ac1c726cd0184eeb 801 SUPERFAMILY SSF56784 415 637 1.9E-33 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS11900 07d28d40101ffbd6ac1c726cd0184eeb 801 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 317 323 - T 10-11-2016 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 A4G23_RS11900 07d28d40101ffbd6ac1c726cd0184eeb 801 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 586 611 3.1E-7 T 10-11-2016 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A4G23_RS11900 07d28d40101ffbd6ac1c726cd0184eeb 801 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 418 436 3.1E-7 T 10-11-2016 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A4G23_RS11900 07d28d40101ffbd6ac1c726cd0184eeb 801 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 555 571 3.1E-7 T 10-11-2016 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A4G23_RS11900 07d28d40101ffbd6ac1c726cd0184eeb 801 Gene3D G3DSA:3.40.1110.10 305 332 2.0E-5 T 10-11-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A4G23_RS11900 07d28d40101ffbd6ac1c726cd0184eeb 801 Pfam PF00122 E1-E2 ATPase 86 306 1.0E-49 T 10-11-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 A4G23_RS11900 07d28d40101ffbd6ac1c726cd0184eeb 801 SUPERFAMILY SSF81665 604 798 2.88E-61 T 10-11-2016 A4G23_RS11900 07d28d40101ffbd6ac1c726cd0184eeb 801 SUPERFAMILY SSF81665 25 117 2.88E-61 T 10-11-2016 A4G23_RS11900 07d28d40101ffbd6ac1c726cd0184eeb 801 SUPERFAMILY SSF81665 215 309 2.88E-61 T 10-11-2016 A4G23_RS11900 07d28d40101ffbd6ac1c726cd0184eeb 801 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 529 643 2.7E-27 T 10-11-2016 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A4G23_RS11900 07d28d40101ffbd6ac1c726cd0184eeb 801 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 88 333 2.2E-30 T 10-11-2016 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A4G23_RS11900 07d28d40101ffbd6ac1c726cd0184eeb 801 Gene3D G3DSA:3.40.1110.10 357 438 3.1E-4 T 10-11-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A4G23_RS11900 07d28d40101ffbd6ac1c726cd0184eeb 801 Gene3D G3DSA:1.20.1110.10 524 790 2.5E-54 T 10-11-2016 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A4G23_RS11900 07d28d40101ffbd6ac1c726cd0184eeb 801 Gene3D G3DSA:1.20.1110.10 84 111 2.5E-54 T 10-11-2016 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A4G23_RS21370 7c2a7c1538836dc1170429de3d23a666 254 ProSitePatterns PS00893 Nudix box signature. 49 70 - T 10-11-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A4G23_RS21370 7c2a7c1538836dc1170429de3d23a666 254 Pfam PF00293 NUDIX domain 15 142 5.9E-19 T 10-11-2016 IPR000086 NUDIX hydrolase domain GO:0016787 A4G23_RS21370 7c2a7c1538836dc1170429de3d23a666 254 SUPERFAMILY SSF55811 4 174 1.9E-29 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS21370 7c2a7c1538836dc1170429de3d23a666 254 Gene3D G3DSA:1.10.10.10 169 242 4.2E-27 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS21370 7c2a7c1538836dc1170429de3d23a666 254 Gene3D G3DSA:3.90.79.10 3 165 3.0E-49 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS21370 7c2a7c1538836dc1170429de3d23a666 254 SUPERFAMILY SSF46785 177 247 1.06E-17 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS13790 771e85ff19786e0d7cb75ea064bb9f8d 312 Gene3D G3DSA:3.40.190.10 94 171 2.6E-20 T 10-11-2016 A4G23_RS13790 771e85ff19786e0d7cb75ea064bb9f8d 312 Pfam PF00800 Prephenate dehydratase 8 184 4.4E-47 T 10-11-2016 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 A4G23_RS13790 771e85ff19786e0d7cb75ea064bb9f8d 312 SUPERFAMILY SSF53850 5 188 3.14E-50 T 10-11-2016 A4G23_RS13790 771e85ff19786e0d7cb75ea064bb9f8d 312 Gene3D G3DSA:3.40.190.10 4 93 3.2E-25 T 10-11-2016 A4G23_RS13790 771e85ff19786e0d7cb75ea064bb9f8d 312 Gene3D G3DSA:3.30.70.260 190 277 1.1E-28 T 10-11-2016 A4G23_RS13790 771e85ff19786e0d7cb75ea064bb9f8d 312 ProSitePatterns PS00857 Prephenate dehydratase signature 1. 159 181 - T 10-11-2016 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 A4G23_RS13790 771e85ff19786e0d7cb75ea064bb9f8d 312 PIRSF PIRSF001500 2 279 9.2E-59 T 10-11-2016 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 A4G23_RS13790 771e85ff19786e0d7cb75ea064bb9f8d 312 SUPERFAMILY SSF55021 178 276 1.45E-22 T 10-11-2016 A4G23_RS14415 c533911b9d8d77e676e251652ae2bb6e 616 Gene3D G3DSA:3.30.420.40 289 331 3.9E-34 T 10-11-2016 A4G23_RS14415 c533911b9d8d77e676e251652ae2bb6e 616 Gene3D G3DSA:3.30.420.40 169 199 3.9E-34 T 10-11-2016 A4G23_RS14415 c533911b9d8d77e676e251652ae2bb6e 616 Gene3D G3DSA:3.30.420.40 4 38 4.2E-56 T 10-11-2016 A4G23_RS14415 c533911b9d8d77e676e251652ae2bb6e 616 Gene3D G3DSA:3.30.420.40 101 168 4.2E-56 T 10-11-2016 A4G23_RS14415 c533911b9d8d77e676e251652ae2bb6e 616 Gene3D G3DSA:3.90.640.10 200 285 1.5E-31 T 10-11-2016 A4G23_RS14415 c533911b9d8d77e676e251652ae2bb6e 616 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 608 36.223 T 10-11-2016 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453 A4G23_RS14415 c533911b9d8d77e676e251652ae2bb6e 616 Pfam PF00012 Hsp70 protein 4 78 6.8E-29 T 10-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4G23_RS14415 c533911b9d8d77e676e251652ae2bb6e 616 Pfam PF00012 Hsp70 protein 80 574 7.0E-221 T 10-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4G23_RS14415 c533911b9d8d77e676e251652ae2bb6e 616 Gene3D G3DSA:1.20.1270.10 504 574 4.6E-28 T 10-11-2016 IPR029048 Heat shock protein 70kD, C-terminal domain Reactome: R-HSA-3371453 A4G23_RS14415 c533911b9d8d77e676e251652ae2bb6e 616 SUPERFAMILY SSF100934 478 575 1.24E-14 T 10-11-2016 IPR029048 Heat shock protein 70kD, C-terminal domain Reactome: R-HSA-3371453 A4G23_RS14415 c533911b9d8d77e676e251652ae2bb6e 616 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 4 574 1.3E-278 T 10-11-2016 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453 A4G23_RS14415 c533911b9d8d77e676e251652ae2bb6e 616 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 166 179 - T 10-11-2016 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 A4G23_RS14415 c533911b9d8d77e676e251652ae2bb6e 616 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 10-11-2016 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 A4G23_RS14415 c533911b9d8d77e676e251652ae2bb6e 616 Gene3D G3DSA:2.60.34.10 361 503 1.4E-72 T 10-11-2016 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 A4G23_RS14415 c533911b9d8d77e676e251652ae2bb6e 616 PRINTS PR00301 70kDa heat shock protein signature 54 62 3.8E-74 T 10-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4G23_RS14415 c533911b9d8d77e676e251652ae2bb6e 616 PRINTS PR00301 70kDa heat shock protein signature 31 43 3.8E-74 T 10-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4G23_RS14415 c533911b9d8d77e676e251652ae2bb6e 616 PRINTS PR00301 70kDa heat shock protein signature 359 378 3.8E-74 T 10-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4G23_RS14415 c533911b9d8d77e676e251652ae2bb6e 616 PRINTS PR00301 70kDa heat shock protein signature 304 320 3.8E-74 T 10-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4G23_RS14415 c533911b9d8d77e676e251652ae2bb6e 616 PRINTS PR00301 70kDa heat shock protein signature 3 16 3.8E-74 T 10-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4G23_RS14415 c533911b9d8d77e676e251652ae2bb6e 616 PRINTS PR00301 70kDa heat shock protein signature 336 356 3.8E-74 T 10-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4G23_RS14415 c533911b9d8d77e676e251652ae2bb6e 616 PRINTS PR00301 70kDa heat shock protein signature 440 456 3.8E-74 T 10-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4G23_RS14415 c533911b9d8d77e676e251652ae2bb6e 616 PRINTS PR00301 70kDa heat shock protein signature 114 134 3.8E-74 T 10-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4G23_RS14415 c533911b9d8d77e676e251652ae2bb6e 616 PRINTS PR00301 70kDa heat shock protein signature 172 182 3.8E-74 T 10-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4G23_RS14415 c533911b9d8d77e676e251652ae2bb6e 616 SUPERFAMILY SSF53067 161 353 3.21E-65 T 10-11-2016 A4G23_RS14415 c533911b9d8d77e676e251652ae2bb6e 616 SUPERFAMILY SSF100920 355 511 3.79E-60 T 10-11-2016 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 A4G23_RS14415 c533911b9d8d77e676e251652ae2bb6e 616 Gene3D G3DSA:3.30.30.30 39 100 4.5E-16 T 10-11-2016 A4G23_RS14415 c533911b9d8d77e676e251652ae2bb6e 616 SUPERFAMILY SSF53067 4 160 4.7E-58 T 10-11-2016 A4G23_RS14415 c533911b9d8d77e676e251652ae2bb6e 616 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 307 321 - T 10-11-2016 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 A4G23_RS25605 02575b5ae830f8bb1dd90709d730fe8d 225 Pfam PF11139 Sap, sulfolipid-1-addressing protein 8 220 2.8E-46 T 10-11-2016 IPR021315 Glycolipid exporter Gap/Sap A4G23_RS13245 8e6ea9f245811bfaf3bb429aae2bf0e0 170 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 48 67 1.7E-9 T 10-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 A4G23_RS13245 8e6ea9f245811bfaf3bb429aae2bf0e0 170 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 37 48 1.7E-9 T 10-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 A4G23_RS13245 8e6ea9f245811bfaf3bb429aae2bf0e0 170 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 37 1.7E-9 T 10-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 A4G23_RS13245 8e6ea9f245811bfaf3bb429aae2bf0e0 170 Gene3D G3DSA:1.10.10.10 20 72 4.8E-19 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS13245 8e6ea9f245811bfaf3bb429aae2bf0e0 170 SUPERFAMILY SSF54909 84 159 1.13E-13 T 10-11-2016 IPR011008 Dimeric alpha-beta barrel A4G23_RS13245 8e6ea9f245811bfaf3bb429aae2bf0e0 170 SUPERFAMILY SSF46785 21 80 2.63E-14 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS13245 8e6ea9f245811bfaf3bb429aae2bf0e0 170 Pfam PF01037 Lrp/AsnC ligand binding domain 94 158 3.5E-12 T 10-11-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A4G23_RS13245 8e6ea9f245811bfaf3bb429aae2bf0e0 170 Pfam PF13412 Winged helix-turn-helix DNA-binding 21 68 9.1E-15 T 10-11-2016 A4G23_RS13245 8e6ea9f245811bfaf3bb429aae2bf0e0 170 SMART SM00344 21 127 4.8E-23 T 10-11-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A4G23_RS13245 8e6ea9f245811bfaf3bb429aae2bf0e0 170 Gene3D G3DSA:3.30.70.920 73 163 3.3E-21 T 10-11-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A4G23_RS22185 11cebff3593a35998c83dce56b6294f1 311 Pfam PF13602 Zinc-binding dehydrogenase 182 309 1.0E-22 T 10-11-2016 A4G23_RS22185 11cebff3593a35998c83dce56b6294f1 311 SUPERFAMILY SSF51735 113 239 2.22E-32 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS22185 11cebff3593a35998c83dce56b6294f1 311 SMART SM00829 10 309 7.7E-28 T 10-11-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A4G23_RS22185 11cebff3593a35998c83dce56b6294f1 311 Gene3D G3DSA:3.40.50.720 144 239 7.9E-21 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS22185 11cebff3593a35998c83dce56b6294f1 311 Gene3D G3DSA:3.90.180.10 1 143 4.8E-42 T 10-11-2016 IPR011032 GroES-like A4G23_RS22185 11cebff3593a35998c83dce56b6294f1 311 SUPERFAMILY SSF50129 1 135 3.04E-34 T 10-11-2016 IPR011032 GroES-like A4G23_RS14085 5ce8cd138b789a34df2b9580534b0be4 138 SUPERFAMILY SSF54913 1 96 3.11E-31 T 10-11-2016 IPR011322 Nitrogen regulatory PII-like, alpha/beta A4G23_RS14085 5ce8cd138b789a34df2b9580534b0be4 138 Pfam PF02641 Uncharacterized ACR, COG1993 1 95 3.6E-35 T 10-11-2016 IPR003793 Domain of unknown function DUF190 A4G23_RS14085 5ce8cd138b789a34df2b9580534b0be4 138 Gene3D G3DSA:3.30.70.120 1 104 7.2E-41 T 10-11-2016 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal A4G23_RS12100 152e6b3f2a1d8e4ce33a329a363e8315 386 PRINTS PR00344 Bacterial sensor protein C-terminal signature 318 332 3.4E-6 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS12100 152e6b3f2a1d8e4ce33a329a363e8315 386 PRINTS PR00344 Bacterial sensor protein C-terminal signature 365 378 3.4E-6 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS12100 152e6b3f2a1d8e4ce33a329a363e8315 386 PRINTS PR00344 Bacterial sensor protein C-terminal signature 341 359 3.4E-6 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS12100 152e6b3f2a1d8e4ce33a329a363e8315 386 Pfam PF07730 Histidine kinase 176 243 2.5E-17 T 10-11-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4G23_RS12100 152e6b3f2a1d8e4ce33a329a363e8315 386 SUPERFAMILY SSF55874 253 379 4.06E-18 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS12100 152e6b3f2a1d8e4ce33a329a363e8315 386 SMART SM00387 282 381 0.0013 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS12100 152e6b3f2a1d8e4ce33a329a363e8315 386 PIRSF PIRSF037434 1 386 1.1E-125 T 10-11-2016 IPR017205 Signal transduction histidine kinase, ChrS A4G23_RS12100 152e6b3f2a1d8e4ce33a329a363e8315 386 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 287 379 3.0E-6 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS12100 152e6b3f2a1d8e4ce33a329a363e8315 386 Gene3D G3DSA:3.30.565.10 284 380 3.8E-11 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS10275 eeae4bcf78ea5260d4584edd3565b332 286 SUPERFAMILY SSF46689 16 76 2.15E-14 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS10275 eeae4bcf78ea5260d4584edd3565b332 286 Pfam PF01418 Helix-turn-helix domain, rpiR family 15 75 3.4E-12 T 10-11-2016 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 A4G23_RS10275 eeae4bcf78ea5260d4584edd3565b332 286 SUPERFAMILY SSF53697 100 240 3.34E-9 T 10-11-2016 A4G23_RS10275 eeae4bcf78ea5260d4584edd3565b332 286 Gene3D G3DSA:1.10.10.10 16 76 4.4E-18 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS10275 eeae4bcf78ea5260d4584edd3565b332 286 Gene3D G3DSA:3.40.50.10490 104 244 9.7E-8 T 10-11-2016 A4G23_RS20645 9e131eb3b37fd629a761e5abf1417a42 439 Gene3D G3DSA:3.40.640.10 51 325 2.0E-84 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS20645 9e131eb3b37fd629a761e5abf1417a42 439 Gene3D G3DSA:3.90.1150.10 2 49 8.6E-32 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS20645 9e131eb3b37fd629a761e5abf1417a42 439 Gene3D G3DSA:3.90.1150.10 326 434 8.6E-32 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS20645 9e131eb3b37fd629a761e5abf1417a42 439 SUPERFAMILY SSF53383 2 434 5.91E-125 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS20645 9e131eb3b37fd629a761e5abf1417a42 439 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 237 274 - T 10-11-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4G23_RS20645 9e131eb3b37fd629a761e5abf1417a42 439 Pfam PF00202 Aminotransferase class-III 15 431 6.7E-102 T 10-11-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4G23_RS07110 09870b598f1bd59f9de6a0d2a1a7c39f 240 Pfam PF01081 KDPG and KHG aldolase 19 206 2.0E-63 T 10-11-2016 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 A4G23_RS07110 09870b598f1bd59f9de6a0d2a1a7c39f 240 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 18 213 1.5E-70 T 10-11-2016 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 A4G23_RS07110 09870b598f1bd59f9de6a0d2a1a7c39f 240 ProSitePatterns PS00159 KDPG and KHG aldolases active site. 44 53 - T 10-11-2016 IPR031337 KDPG/KHG aldolase, active site 1 KEGG: 00030+4.1.2.14|KEGG: 00330+4.1.3.16|KEGG: 00630+4.1.3.16|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 A4G23_RS07110 09870b598f1bd59f9de6a0d2a1a7c39f 240 Gene3D G3DSA:3.20.20.70 18 214 3.9E-69 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS07110 09870b598f1bd59f9de6a0d2a1a7c39f 240 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 132 145 - T 10-11-2016 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 A4G23_RS07110 09870b598f1bd59f9de6a0d2a1a7c39f 240 SUPERFAMILY SSF51569 18 213 2.01E-61 T 10-11-2016 A4G23_RS26750 d2af540e89963898ca7a8834bad02379 218 Pfam PF00857 Isochorismatase family 33 202 1.2E-37 T 10-11-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 A4G23_RS26750 d2af540e89963898ca7a8834bad02379 218 PRINTS PR01398 Isochorismatase signature 79 98 5.9E-49 T 10-11-2016 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 A4G23_RS26750 d2af540e89963898ca7a8834bad02379 218 PRINTS PR01398 Isochorismatase signature 185 202 5.9E-49 T 10-11-2016 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 A4G23_RS26750 d2af540e89963898ca7a8834bad02379 218 PRINTS PR01398 Isochorismatase signature 3 15 5.9E-49 T 10-11-2016 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 A4G23_RS26750 d2af540e89963898ca7a8834bad02379 218 PRINTS PR01398 Isochorismatase signature 167 185 5.9E-49 T 10-11-2016 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 A4G23_RS26750 d2af540e89963898ca7a8834bad02379 218 PRINTS PR01398 Isochorismatase signature 111 133 5.9E-49 T 10-11-2016 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 A4G23_RS26750 d2af540e89963898ca7a8834bad02379 218 PRINTS PR01398 Isochorismatase signature 62 79 5.9E-49 T 10-11-2016 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 A4G23_RS26750 d2af540e89963898ca7a8834bad02379 218 Gene3D G3DSA:3.40.50.850 4 210 8.3E-61 T 10-11-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 A4G23_RS26750 d2af540e89963898ca7a8834bad02379 218 PIRSF PIRSF001111 2 216 1.3E-89 T 10-11-2016 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 A4G23_RS26750 d2af540e89963898ca7a8834bad02379 218 SUPERFAMILY SSF52499 3 209 4.84E-64 T 10-11-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 A4G23_RS24280 51310d2a68ac4a19f3f8b21c06945703 326 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 17 247 1.7E-46 T 10-11-2016 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 A4G23_RS24280 51310d2a68ac4a19f3f8b21c06945703 326 PIRSF PIRSF015582 1 325 6.4E-94 T 10-11-2016 IPR011206 Citrate lyase beta subunit-like A4G23_RS24280 51310d2a68ac4a19f3f8b21c06945703 326 Gene3D G3DSA:3.20.20.60 12 258 1.8E-78 T 10-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A4G23_RS24280 51310d2a68ac4a19f3f8b21c06945703 326 SUPERFAMILY SSF51621 13 258 4.08E-66 T 10-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A4G23_RS00575 630906d56404f0fc7dd3ae1b97528143 480 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 150 221 1.3E-5 T 10-11-2016 IPR000014 PAS domain A4G23_RS00575 630906d56404f0fc7dd3ae1b97528143 480 SMART SM00086 173 215 5.9E-6 T 10-11-2016 IPR001610 PAC motif A4G23_RS00575 630906d56404f0fc7dd3ae1b97528143 480 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 294 458 1.4E-33 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS00575 630906d56404f0fc7dd3ae1b97528143 480 Pfam PF08447 PAS fold 122 205 3.1E-11 T 10-11-2016 IPR013655 PAS fold-3 GO:0005515 A4G23_RS00575 630906d56404f0fc7dd3ae1b97528143 480 SMART SM00331 268 476 1.8E-10 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS00575 630906d56404f0fc7dd3ae1b97528143 480 Gene3D G3DSA:3.30.450.20 110 213 1.6E-13 T 10-11-2016 A4G23_RS00575 630906d56404f0fc7dd3ae1b97528143 480 SUPERFAMILY SSF55785 123 223 1.65E-12 T 10-11-2016 IPR000014 PAS domain A4G23_RS07950 2066191f00c2ce92dd896f764fa9f974 629 Gene3D G3DSA:3.40.50.980 211 301 1.1E-24 T 10-11-2016 A4G23_RS07950 2066191f00c2ce92dd896f764fa9f974 629 Gene3D G3DSA:3.40.50.980 360 422 1.1E-24 T 10-11-2016 A4G23_RS07950 2066191f00c2ce92dd896f764fa9f974 629 Gene3D G3DSA:3.40.50.980 189 210 2.3E-35 T 10-11-2016 A4G23_RS07950 2066191f00c2ce92dd896f764fa9f974 629 Gene3D G3DSA:3.40.50.980 13 157 2.3E-35 T 10-11-2016 A4G23_RS07950 2066191f00c2ce92dd896f764fa9f974 629 Pfam PF00501 AMP-binding enzyme 20 493 7.4E-96 T 10-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A4G23_RS07950 2066191f00c2ce92dd896f764fa9f974 629 ProSitePatterns PS00455 Putative AMP-binding domain signature. 204 215 - T 10-11-2016 IPR020845 AMP-binding, conserved site A4G23_RS07950 2066191f00c2ce92dd896f764fa9f974 629 SUPERFAMILY SSF56801 363 624 1.7E-118 T 10-11-2016 A4G23_RS07950 2066191f00c2ce92dd896f764fa9f974 629 SUPERFAMILY SSF56801 8 306 1.7E-118 T 10-11-2016 A4G23_RS07950 2066191f00c2ce92dd896f764fa9f974 629 Gene3D G3DSA:2.30.38.10 423 484 1.3E-21 T 10-11-2016 A4G23_RS12075 0ee157c0acce680aad0c3a3a5172000b 145 Pfam PF00472 RF-1 domain 13 139 1.6E-21 T 10-11-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 A4G23_RS12075 0ee157c0acce680aad0c3a3a5172000b 145 Gene3D G3DSA:3.30.160.200 13 110 6.9E-27 T 10-11-2016 A4G23_RS12075 0ee157c0acce680aad0c3a3a5172000b 145 SUPERFAMILY SSF110916 4 108 9.55E-13 T 10-11-2016 A4G23_RS17010 4aa2a19f97ce86f4a007d77e9adf0e8d 807 Gene3D G3DSA:3.30.200.20 57 154 9.0E-22 T 10-11-2016 A4G23_RS17010 4aa2a19f97ce86f4a007d77e9adf0e8d 807 SUPERFAMILY SSF56112 129 343 4.99E-69 T 10-11-2016 IPR011009 Protein kinase-like domain A4G23_RS17010 4aa2a19f97ce86f4a007d77e9adf0e8d 807 SUPERFAMILY SSF56112 61 100 4.99E-69 T 10-11-2016 IPR011009 Protein kinase-like domain A4G23_RS17010 4aa2a19f97ce86f4a007d77e9adf0e8d 807 SMART SM00220 65 344 7.2E-64 T 10-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4G23_RS17010 4aa2a19f97ce86f4a007d77e9adf0e8d 807 Gene3D G3DSA:1.10.510.10 155 337 6.2E-50 T 10-11-2016 A4G23_RS17010 4aa2a19f97ce86f4a007d77e9adf0e8d 807 Pfam PF00069 Protein kinase domain 132 336 2.8E-41 T 10-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4G23_RS17010 4aa2a19f97ce86f4a007d77e9adf0e8d 807 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 71 94 - T 10-11-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 A4G23_RS17010 4aa2a19f97ce86f4a007d77e9adf0e8d 807 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 208 220 - T 10-11-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 A4G23_RS00040 033facf7472c3940ec36af7a2d2f382d 654 Gene3D G3DSA:1.10.287.510 283 403 4.5E-6 T 10-11-2016 A4G23_RS00040 033facf7472c3940ec36af7a2d2f382d 654 SUPERFAMILY SSF52540 201 237 4.81E-5 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS00040 033facf7472c3940ec36af7a2d2f382d 654 SUPERFAMILY SSF52540 18 132 4.81E-5 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS00040 033facf7472c3940ec36af7a2d2f382d 654 SUPERFAMILY SSF52540 396 417 4.81E-5 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS00040 033facf7472c3940ec36af7a2d2f382d 654 SUPERFAMILY SSF52540 480 570 4.81E-5 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS00040 033facf7472c3940ec36af7a2d2f382d 654 Gene3D G3DSA:3.40.50.300 450 451 3.4E-6 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS00040 033facf7472c3940ec36af7a2d2f382d 654 Gene3D G3DSA:3.40.50.300 220 221 3.4E-6 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS00040 033facf7472c3940ec36af7a2d2f382d 654 Gene3D G3DSA:3.40.50.300 523 582 3.4E-6 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS00040 033facf7472c3940ec36af7a2d2f382d 654 Gene3D G3DSA:3.40.50.300 18 87 3.4E-6 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS00040 033facf7472c3940ec36af7a2d2f382d 654 Pfam PF12532 Protein of unknown function (DUF3732) 465 643 5.7E-50 T 10-11-2016 IPR022205 Protein of unknown function DUF3732 A4G23_RS24350 49a17f3ce00f2b98e9c4de9b8ac256c5 154 Pfam PF01037 Lrp/AsnC ligand binding domain 67 139 2.0E-20 T 10-11-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A4G23_RS24350 49a17f3ce00f2b98e9c4de9b8ac256c5 154 SMART SM00344 1 110 8.2E-45 T 10-11-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A4G23_RS24350 49a17f3ce00f2b98e9c4de9b8ac256c5 154 SUPERFAMILY SSF54909 62 149 1.1E-19 T 10-11-2016 IPR011008 Dimeric alpha-beta barrel A4G23_RS24350 49a17f3ce00f2b98e9c4de9b8ac256c5 154 Gene3D G3DSA:3.30.70.920 54 138 7.8E-27 T 10-11-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A4G23_RS24350 49a17f3ce00f2b98e9c4de9b8ac256c5 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 4.3E-16 T 10-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 A4G23_RS24350 49a17f3ce00f2b98e9c4de9b8ac256c5 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 4.3E-16 T 10-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 A4G23_RS24350 49a17f3ce00f2b98e9c4de9b8ac256c5 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 4.3E-16 T 10-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 A4G23_RS24350 49a17f3ce00f2b98e9c4de9b8ac256c5 154 SUPERFAMILY SSF46785 1 90 3.67E-19 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS24350 49a17f3ce00f2b98e9c4de9b8ac256c5 154 Gene3D G3DSA:1.10.10.10 2 52 2.6E-26 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS24350 49a17f3ce00f2b98e9c4de9b8ac256c5 154 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 48 3.1E-21 T 10-11-2016 A4G23_RS00105 d855987217524878185322e1402529db 1002 SUPERFAMILY SSF52540 123 244 6.96E-28 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS00105 d855987217524878185322e1402529db 1002 SUPERFAMILY SSF52540 1 94 6.96E-28 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS00105 d855987217524878185322e1402529db 1002 SUPERFAMILY SSF52540 839 984 6.96E-28 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS00105 d855987217524878185322e1402529db 1002 Pfam PF13476 AAA domain 6 308 4.3E-23 T 10-11-2016 A4G23_RS00105 d855987217524878185322e1402529db 1002 Pfam PF13558 Putative exonuclease SbcCD, C subunit 891 957 1.4E-12 T 10-11-2016 A4G23_RS00105 d855987217524878185322e1402529db 1002 Gene3D G3DSA:3.40.50.300 853 998 5.6E-35 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS00105 d855987217524878185322e1402529db 1002 Gene3D G3DSA:3.40.50.300 642 643 5.6E-35 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS00105 d855987217524878185322e1402529db 1002 Gene3D G3DSA:3.40.50.300 1 181 5.6E-35 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS27335 d855987217524878185322e1402529db 1002 SUPERFAMILY SSF52540 123 244 6.96E-28 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS27335 d855987217524878185322e1402529db 1002 SUPERFAMILY SSF52540 1 94 6.96E-28 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS27335 d855987217524878185322e1402529db 1002 SUPERFAMILY SSF52540 839 984 6.96E-28 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS27335 d855987217524878185322e1402529db 1002 Pfam PF13476 AAA domain 6 308 4.3E-23 T 10-11-2016 A4G23_RS27335 d855987217524878185322e1402529db 1002 Pfam PF13558 Putative exonuclease SbcCD, C subunit 891 957 1.4E-12 T 10-11-2016 A4G23_RS27335 d855987217524878185322e1402529db 1002 Gene3D G3DSA:3.40.50.300 853 998 5.6E-35 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS27335 d855987217524878185322e1402529db 1002 Gene3D G3DSA:3.40.50.300 642 643 5.6E-35 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS27335 d855987217524878185322e1402529db 1002 Gene3D G3DSA:3.40.50.300 1 181 5.6E-35 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS20745 550e4ad440fcdd928e492177654ab348 327 SUPERFAMILY SSF53901 3 326 2.68E-62 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS20745 550e4ad440fcdd928e492177654ab348 327 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 1 326 59.473 T 10-11-2016 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A4G23_RS20745 550e4ad440fcdd928e492177654ab348 327 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 237 326 7.8E-31 T 10-11-2016 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A4G23_RS20745 550e4ad440fcdd928e492177654ab348 327 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 1 326 1.6E-103 T 10-11-2016 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A4G23_RS20745 550e4ad440fcdd928e492177654ab348 327 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 106 184 2.9E-23 T 10-11-2016 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A4G23_RS20745 550e4ad440fcdd928e492177654ab348 327 Gene3D G3DSA:3.40.47.10 162 326 4.3E-48 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS20745 550e4ad440fcdd928e492177654ab348 327 Gene3D G3DSA:3.40.47.10 2 161 1.5E-58 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS11210 30337c0f0bfb705bd459daca08b34e77 374 SUPERFAMILY SSF53383 8 371 2.42E-104 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS11210 30337c0f0bfb705bd459daca08b34e77 374 Gene3D G3DSA:3.90.1150.10 248 372 6.8E-37 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS11210 30337c0f0bfb705bd459daca08b34e77 374 PIRSF PIRSF000390 2 373 9.2E-103 T 10-11-2016 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A4G23_RS11210 30337c0f0bfb705bd459daca08b34e77 374 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 15 368 4.9E-113 T 10-11-2016 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A4G23_RS11210 30337c0f0bfb705bd459daca08b34e77 374 Gene3D G3DSA:3.40.640.10 17 246 1.3E-74 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS04980 13b36772378a49e51365e85a519ded4f 348 Gene3D G3DSA:3.40.50.10410 98 203 2.3E-25 T 10-11-2016 IPR023215 Nitrophenylphosphatase-like domain A4G23_RS04980 13b36772378a49e51365e85a519ded4f 348 SUPERFAMILY SSF56784 25 279 1.75E-54 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS04980 13b36772378a49e51365e85a519ded4f 348 Pfam PF13344 Haloacid dehalogenase-like hydrolase 29 128 1.1E-25 T 10-11-2016 IPR006357 HAD-superfamily hydrolase, subfamily IIA A4G23_RS04980 13b36772378a49e51365e85a519ded4f 348 Pfam PF13242 HAD-hyrolase-like 205 276 2.9E-16 T 10-11-2016 A4G23_RS04980 13b36772378a49e51365e85a519ded4f 348 Gene3D G3DSA:3.40.50.1000 204 279 6.0E-34 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS04980 13b36772378a49e51365e85a519ded4f 348 Gene3D G3DSA:3.40.50.1000 23 97 6.0E-34 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS04980 13b36772378a49e51365e85a519ded4f 348 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 29 252 7.2E-33 T 10-11-2016 IPR006357 HAD-superfamily hydrolase, subfamily IIA A4G23_RS19845 dc227ebaae9301e35f5c4b214731da14 681 Hamap MF_02124 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase [glgE]. 4 655 46.269 T 10-11-2016 IPR026585 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase GO:0016757 KEGG: 00500+2.4.99.16 A4G23_RS19845 dc227ebaae9301e35f5c4b214731da14 681 Pfam PF11896 Domain of unknown function (DUF3416) 6 193 7.2E-58 T 10-11-2016 IPR021828 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase, domain N/S GO:0004553 KEGG: 00500+2.4.99.16 A4G23_RS19845 dc227ebaae9301e35f5c4b214731da14 681 SMART SM00642 203 530 0.0021 T 10-11-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A4G23_RS19845 dc227ebaae9301e35f5c4b214731da14 681 Gene3D G3DSA:3.20.20.80 198 560 8.5E-70 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS19845 dc227ebaae9301e35f5c4b214731da14 681 SUPERFAMILY SSF51445 199 562 7.31E-84 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS19845 dc227ebaae9301e35f5c4b214731da14 681 SUPERFAMILY SSF51011 567 643 1.82E-6 T 10-11-2016 A4G23_RS19845 dc227ebaae9301e35f5c4b214731da14 681 Gene3D G3DSA:2.60.40.1180 566 643 6.4E-12 T 10-11-2016 IPR013780 Glycosyl hydrolase, all-beta A4G23_RS12710 635906f00dd0e04049fd8acc37526a6f 580 SUPERFAMILY SSF55874 490 576 1.46E-6 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS12710 635906f00dd0e04049fd8acc37526a6f 580 SMART SM00331 234 444 1.5E-40 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS12710 635906f00dd0e04049fd8acc37526a6f 580 SUPERFAMILY SSF81606 247 443 1.49E-8 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS12710 635906f00dd0e04049fd8acc37526a6f 580 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 261 444 3.3E-50 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS12710 635906f00dd0e04049fd8acc37526a6f 580 Pfam PF13581 Histidine kinase-like ATPase domain 468 560 3.0E-7 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS12710 635906f00dd0e04049fd8acc37526a6f 580 Gene3D G3DSA:3.30.450.20 86 197 2.3E-6 T 10-11-2016 A4G23_RS24785 fcf9213d6287d3e692c1f931b54c27eb 527 Gene3D G3DSA:1.10.390.10 328 461 1.1E-20 T 10-11-2016 A4G23_RS24785 fcf9213d6287d3e692c1f931b54c27eb 527 SUPERFAMILY SSF63737 32 224 5.75E-35 T 10-11-2016 A4G23_RS24785 fcf9213d6287d3e692c1f931b54c27eb 527 Pfam PF01433 Peptidase family M1 49 356 1.8E-40 T 10-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4G23_RS24785 fcf9213d6287d3e692c1f931b54c27eb 527 SUPERFAMILY SSF55486 248 462 1.41E-49 T 10-11-2016 A4G23_RS24785 fcf9213d6287d3e692c1f931b54c27eb 527 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 161 176 6.9E-11 T 10-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4G23_RS24785 fcf9213d6287d3e692c1f931b54c27eb 527 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 314 329 6.9E-11 T 10-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4G23_RS24785 fcf9213d6287d3e692c1f931b54c27eb 527 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 333 345 6.9E-11 T 10-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4G23_RS24785 fcf9213d6287d3e692c1f931b54c27eb 527 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 208 223 6.9E-11 T 10-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4G23_RS08060 60a049ae38f2404749ccb848e32d1e53 217 SUPERFAMILY SSF53254 10 208 8.1E-56 T 10-11-2016 IPR029033 Histidine phosphatase superfamily A4G23_RS08060 60a049ae38f2404749ccb848e32d1e53 217 Gene3D G3DSA:3.40.50.1240 10 205 2.1E-58 T 10-11-2016 IPR029033 Histidine phosphatase superfamily A4G23_RS08060 60a049ae38f2404749ccb848e32d1e53 217 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 12 204 2.9E-55 T 10-11-2016 IPR013078 Histidine phosphatase superfamily, clade-1 A4G23_RS08060 60a049ae38f2404749ccb848e32d1e53 217 SMART SM00855 11 165 3.4E-23 T 10-11-2016 IPR013078 Histidine phosphatase superfamily, clade-1 A4G23_RS08060 60a049ae38f2404749ccb848e32d1e53 217 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 14 23 - T 10-11-2016 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 A4G23_RS04435 48985f6a0c8fe4b90f98d01eec38d405 844 SUPERFAMILY SSF52540 568 629 6.9E-18 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS04435 48985f6a0c8fe4b90f98d01eec38d405 844 SUPERFAMILY SSF52540 670 814 6.9E-18 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS04435 48985f6a0c8fe4b90f98d01eec38d405 844 Pfam PF14490 Helix-hairpin-helix containing domain 283 366 7.2E-10 T 10-11-2016 IPR029493 RecD helicase-like helix-hairpin-helix domain A4G23_RS04435 48985f6a0c8fe4b90f98d01eec38d405 844 Gene3D G3DSA:3.40.50.300 572 700 3.9E-17 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS04435 48985f6a0c8fe4b90f98d01eec38d405 844 Gene3D G3DSA:3.40.50.300 749 810 3.9E-17 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05365 c06f3a0ec298432be28cafd43363bd95 132 SUPERFAMILY SSF51182 15 127 3.71E-19 T 10-11-2016 IPR011051 RmlC-like cupin domain A4G23_RS05365 c06f3a0ec298432be28cafd43363bd95 132 Hamap MF_01255 L-ectoine synthase [ectC]. 1 129 39.13 T 10-11-2016 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A4G23_RS05365 c06f3a0ec298432be28cafd43363bd95 132 Gene3D G3DSA:2.60.120.10 19 112 1.6E-11 T 10-11-2016 IPR014710 RmlC-like jelly roll fold A4G23_RS05365 c06f3a0ec298432be28cafd43363bd95 132 Pfam PF06339 Ectoine synthase 2 127 6.0E-57 T 10-11-2016 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A4G23_RS05365 c06f3a0ec298432be28cafd43363bd95 132 ProDom PD080544 SYNTHASE 4.2.1.- LYASE L-ECTOINE DEHYDRATASE N-ACETYLDIAMINOBUTYRATE ECTOINE ENZYME SYNTHASE:ECTOINE ECTC 1 119 4.0E-60 T 10-11-2016 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A4G23_RS25750 240ebab355a29e4f1d9337a0e99ec34d 378 SUPERFAMILY SSF55931 12 360 2.16E-83 T 10-11-2016 A4G23_RS25750 240ebab355a29e4f1d9337a0e99ec34d 378 TIGRFAM TIGR02050 gshA_cyan_rel: carboxylate-amine ligase, YbdK family 15 300 2.1E-78 T 10-11-2016 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 A4G23_RS25750 240ebab355a29e4f1d9337a0e99ec34d 378 Hamap MF_01609 Glutamate--cysteine ligase [gshA]. 1 378 73.21 T 10-11-2016 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 A4G23_RS25750 240ebab355a29e4f1d9337a0e99ec34d 378 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 16 298 2.0E-49 T 10-11-2016 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 A4G23_RS03415 f0792eeb1ed527905a99a58a3a9262a4 563 SUPERFAMILY SSF51905 498 539 2.1E-44 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS03415 f0792eeb1ed527905a99a58a3a9262a4 563 SUPERFAMILY SSF51905 48 376 2.1E-44 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS03415 f0792eeb1ed527905a99a58a3a9262a4 563 Gene3D G3DSA:3.40.50.720 47 79 4.2E-11 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS03415 f0792eeb1ed527905a99a58a3a9262a4 563 Gene3D G3DSA:3.90.660.10 365 467 7.0E-27 T 10-11-2016 A4G23_RS03415 f0792eeb1ed527905a99a58a3a9262a4 563 Gene3D G3DSA:3.90.660.10 80 153 7.0E-27 T 10-11-2016 A4G23_RS03415 f0792eeb1ed527905a99a58a3a9262a4 563 Pfam PF01593 Flavin containing amine oxidoreductase 58 532 1.4E-45 T 10-11-2016 IPR002937 Amine oxidase GO:0016491|GO:0055114 A4G23_RS03415 f0792eeb1ed527905a99a58a3a9262a4 563 SUPERFAMILY SSF54373 361 476 1.9E-27 T 10-11-2016 A4G23_RS03415 f0792eeb1ed527905a99a58a3a9262a4 563 Gene3D G3DSA:3.50.50.60 501 545 3.2E-10 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS03415 f0792eeb1ed527905a99a58a3a9262a4 563 Gene3D G3DSA:3.50.50.60 303 361 3.2E-10 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS15100 47e03d7c1d559a1b1ec2fa8c784d53ae 432 Pfam PF13480 Acetyltransferase (GNAT) domain 189 332 3.6E-20 T 10-11-2016 A4G23_RS15100 47e03d7c1d559a1b1ec2fa8c784d53ae 432 SUPERFAMILY SSF55729 188 338 2.81E-10 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS06830 17f502b8b41085f1d5308596a6d38991 569 SUPERFAMILY SSF51445 34 374 1.59E-81 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS06830 17f502b8b41085f1d5308596a6d38991 569 SMART SM00642 36 373 1.9E-80 T 10-11-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A4G23_RS06830 17f502b8b41085f1d5308596a6d38991 569 Gene3D G3DSA:2.60.40.1180 378 455 3.5E-30 T 10-11-2016 IPR013780 Glycosyl hydrolase, all-beta A4G23_RS06830 17f502b8b41085f1d5308596a6d38991 569 Gene3D G3DSA:3.20.20.80 30 377 6.4E-104 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS06830 17f502b8b41085f1d5308596a6d38991 569 SMART SM01065 473 565 4.8E-31 T 10-11-2016 IPR002044 Carbohydrate binding module family 20 GO:2001070 A4G23_RS06830 17f502b8b41085f1d5308596a6d38991 569 PRINTS PR00110 Alpha-amylase signature 200 211 2.0E-24 T 10-11-2016 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 A4G23_RS06830 17f502b8b41085f1d5308596a6d38991 569 PRINTS PR00110 Alpha-amylase signature 229 247 2.0E-24 T 10-11-2016 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 A4G23_RS06830 17f502b8b41085f1d5308596a6d38991 569 PRINTS PR00110 Alpha-amylase signature 79 96 2.0E-24 T 10-11-2016 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 A4G23_RS06830 17f502b8b41085f1d5308596a6d38991 569 PRINTS PR00110 Alpha-amylase signature 287 299 2.0E-24 T 10-11-2016 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 A4G23_RS06830 17f502b8b41085f1d5308596a6d38991 569 PRINTS PR00110 Alpha-amylase signature 111 122 2.0E-24 T 10-11-2016 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 A4G23_RS06830 17f502b8b41085f1d5308596a6d38991 569 SUPERFAMILY SSF49452 477 568 1.15E-32 T 10-11-2016 IPR013784 Carbohydrate-binding-like fold GO:0030246 A4G23_RS06830 17f502b8b41085f1d5308596a6d38991 569 Pfam PF00128 Alpha amylase, catalytic domain 89 338 2.9E-20 T 10-11-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A4G23_RS06830 17f502b8b41085f1d5308596a6d38991 569 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 385 455 8.7E-11 T 10-11-2016 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 A4G23_RS06830 17f502b8b41085f1d5308596a6d38991 569 SUPERFAMILY SSF51011 378 457 6.3E-28 T 10-11-2016 A4G23_RS06830 17f502b8b41085f1d5308596a6d38991 569 SMART SM00632 382 458 3.4E-40 T 10-11-2016 IPR031319 Alpha-amylase, C-terminal domain Reactome: R-HSA-189085 A4G23_RS06830 17f502b8b41085f1d5308596a6d38991 569 Pfam PF00686 Starch binding domain 477 563 1.6E-29 T 10-11-2016 IPR002044 Carbohydrate binding module family 20 GO:2001070 A4G23_RS06830 17f502b8b41085f1d5308596a6d38991 569 Gene3D G3DSA:2.60.40.10 477 568 2.0E-32 T 10-11-2016 IPR013783 Immunoglobulin-like fold A4G23_RS20795 f76e415202e0d1fd445dd62d45861e9e 635 SUPERFAMILY SSF49265 202 294 5.65E-18 T 10-11-2016 IPR003961 Fibronectin type III GO:0005515 A4G23_RS20795 f76e415202e0d1fd445dd62d45861e9e 635 Pfam PF00704 Glycosyl hydrolases family 18 303 618 1.2E-22 T 10-11-2016 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0004553|GO:0005975 A4G23_RS20795 f76e415202e0d1fd445dd62d45861e9e 635 Pfam PF02018 Carbohydrate binding domain 67 182 6.4E-10 T 10-11-2016 IPR003305 Carbohydrate-binding, CenC-like GO:0016798 A4G23_RS20795 f76e415202e0d1fd445dd62d45861e9e 635 SUPERFAMILY SSF51445 302 626 6.23E-55 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS20795 f76e415202e0d1fd445dd62d45861e9e 635 Pfam PF00041 Fibronectin type III domain 208 279 3.5E-6 T 10-11-2016 IPR003961 Fibronectin type III GO:0005515 A4G23_RS20795 f76e415202e0d1fd445dd62d45861e9e 635 SMART SM00060 206 276 6.2E-10 T 10-11-2016 IPR003961 Fibronectin type III GO:0005515 A4G23_RS20795 f76e415202e0d1fd445dd62d45861e9e 635 Gene3D G3DSA:2.60.40.10 204 284 1.7E-18 T 10-11-2016 IPR013783 Immunoglobulin-like fold A4G23_RS20795 f76e415202e0d1fd445dd62d45861e9e 635 Gene3D G3DSA:3.20.20.80 297 625 2.9E-60 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS20795 f76e415202e0d1fd445dd62d45861e9e 635 SUPERFAMILY SSF49785 65 198 3.12E-5 T 10-11-2016 IPR008979 Galactose-binding domain-like A4G23_RS20795 f76e415202e0d1fd445dd62d45861e9e 635 Gene3D G3DSA:2.60.120.260 58 195 2.4E-6 T 10-11-2016 IPR008979 Galactose-binding domain-like A4G23_RS20795 f76e415202e0d1fd445dd62d45861e9e 635 SMART SM00636 301 618 1.4E-6 T 10-11-2016 IPR011583 Chitinase II GO:0004568|GO:0006032 A4G23_RS20795 f76e415202e0d1fd445dd62d45861e9e 635 ProSitePatterns PS01095 Chitinases family 18 active site. 413 421 - T 10-11-2016 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 A4G23_RS08765 b5a1cefdf137eaae5c2590b9c4404365 387 Gene3D G3DSA:3.20.20.70 55 326 1.0E-6 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS08765 b5a1cefdf137eaae5c2590b9c4404365 387 Pfam PF06187 Protein of unknown function (DUF993) 2 385 3.6E-185 T 10-11-2016 IPR009334 Protein of unknown function DUF993 A4G23_RS08765 b5a1cefdf137eaae5c2590b9c4404365 387 SUPERFAMILY SSF51569 51 333 2.62E-13 T 10-11-2016 A4G23_RS21595 cbca83fbfefcb9ef96d2b0894b8e3ff3 217 Pfam PF00072 Response regulator receiver domain 1 107 3.9E-7 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS21595 cbca83fbfefcb9ef96d2b0894b8e3ff3 217 SUPERFAMILY SSF46894 137 208 1.87E-20 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS21595 cbca83fbfefcb9ef96d2b0894b8e3ff3 217 ProSitePatterns PS00622 LuxR-type HTH domain signature. 163 190 - T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS21595 cbca83fbfefcb9ef96d2b0894b8e3ff3 217 Gene3D G3DSA:1.10.10.10 116 208 3.0E-27 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS21595 cbca83fbfefcb9ef96d2b0894b8e3ff3 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 6.5E-14 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS21595 cbca83fbfefcb9ef96d2b0894b8e3ff3 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 6.5E-14 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS21595 cbca83fbfefcb9ef96d2b0894b8e3ff3 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 6.5E-14 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS21595 cbca83fbfefcb9ef96d2b0894b8e3ff3 217 Gene3D G3DSA:3.40.50.2300 1 115 7.3E-12 T 10-11-2016 A4G23_RS21595 cbca83fbfefcb9ef96d2b0894b8e3ff3 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 202 1.6E-17 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS21595 cbca83fbfefcb9ef96d2b0894b8e3ff3 217 SUPERFAMILY SSF52172 1 118 2.85E-12 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS21595 cbca83fbfefcb9ef96d2b0894b8e3ff3 217 SMART SM00421 146 203 5.1E-21 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS26075 398ebba5bf5054d11614bbcf6d81a8af 137 SMART SM00960 9 98 6.7E-21 T 10-11-2016 IPR004942 Roadblock/LAMTOR2 domain A4G23_RS26075 398ebba5bf5054d11614bbcf6d81a8af 137 Gene3D G3DSA:3.30.450.30 8 123 1.0E-18 T 10-11-2016 A4G23_RS26075 398ebba5bf5054d11614bbcf6d81a8af 137 Pfam PF03259 Roadblock/LC7 domain 12 98 1.3E-17 T 10-11-2016 IPR004942 Roadblock/LAMTOR2 domain A4G23_RS26075 398ebba5bf5054d11614bbcf6d81a8af 137 SUPERFAMILY SSF103196 2 124 1.96E-23 T 10-11-2016 A4G23_RS10635 494a656eabf87dc82d613bc57f0d62c3 611 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS10635 494a656eabf87dc82d613bc57f0d62c3 611 Pfam PF12848 ABC transporter 198 272 1.5E-7 T 10-11-2016 IPR032781 ABC-transporter extension domain A4G23_RS10635 494a656eabf87dc82d613bc57f0d62c3 611 Pfam PF16326 ABC transporter C-terminal domain 548 608 8.7E-8 T 10-11-2016 IPR032524 ABC transporter Uup, C-terminal GO:0003677 A4G23_RS10635 494a656eabf87dc82d613bc57f0d62c3 611 SMART SM00382 30 213 8.1E-9 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS10635 494a656eabf87dc82d613bc57f0d62c3 611 SMART SM00382 315 491 4.5E-10 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS10635 494a656eabf87dc82d613bc57f0d62c3 611 SUPERFAMILY SSF52540 284 484 6.33E-39 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS10635 494a656eabf87dc82d613bc57f0d62c3 611 Pfam PF00005 ABC transporter 21 159 8.7E-23 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS10635 494a656eabf87dc82d613bc57f0d62c3 611 Pfam PF00005 ABC transporter 306 447 3.5E-20 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS10635 494a656eabf87dc82d613bc57f0d62c3 611 SUPERFAMILY SSF52540 5 208 5.66E-45 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS10635 494a656eabf87dc82d613bc57f0d62c3 611 ProSitePatterns PS00211 ABC transporters family signature. 419 433 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS10635 494a656eabf87dc82d613bc57f0d62c3 611 Gene3D G3DSA:3.40.50.300 7 251 1.2E-48 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS10635 494a656eabf87dc82d613bc57f0d62c3 611 Gene3D G3DSA:3.40.50.300 289 488 5.6E-39 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS19480 27c4af7a3b5bb837077c2329ee9b9dd5 356 SUPERFAMILY SSF53686 8 332 7.6E-102 T 10-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4G23_RS19480 27c4af7a3b5bb837077c2329ee9b9dd5 356 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 30 323 1.4E-73 T 10-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4G23_RS19480 27c4af7a3b5bb837077c2329ee9b9dd5 356 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 57 70 - T 10-11-2016 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 A4G23_RS19480 27c4af7a3b5bb837077c2329ee9b9dd5 356 Gene3D G3DSA:3.40.50.1100 150 331 1.2E-48 T 10-11-2016 A4G23_RS19480 27c4af7a3b5bb837077c2329ee9b9dd5 356 TIGRFAM TIGR00260 thrC: threonine synthase 13 330 1.6E-97 T 10-11-2016 IPR004450 Threonine synthase-like A4G23_RS19480 27c4af7a3b5bb837077c2329ee9b9dd5 356 Gene3D G3DSA:3.40.50.1100 65 149 1.6E-42 T 10-11-2016 A4G23_RS19480 27c4af7a3b5bb837077c2329ee9b9dd5 356 PIRSF PIRSF038945 1 355 2.5E-168 T 10-11-2016 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 A4G23_RS15365 b826a2ce804ffdf6cb7a6d2d31cf3b03 366 SMART SM00419 296 347 0.0081 T 10-11-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A4G23_RS15365 b826a2ce804ffdf6cb7a6d2d31cf3b03 366 SMART SM00418 284 362 8.0E-23 T 10-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4G23_RS15365 b826a2ce804ffdf6cb7a6d2d31cf3b03 366 Pfam PF12840 Helix-turn-helix domain 285 342 8.8E-15 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS15365 b826a2ce804ffdf6cb7a6d2d31cf3b03 366 Gene3D G3DSA:1.10.10.10 279 362 3.7E-22 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS15365 b826a2ce804ffdf6cb7a6d2d31cf3b03 366 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 333 348 3.2E-7 T 10-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4G23_RS15365 b826a2ce804ffdf6cb7a6d2d31cf3b03 366 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 318 333 3.2E-7 T 10-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4G23_RS15365 b826a2ce804ffdf6cb7a6d2d31cf3b03 366 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 286 301 3.2E-7 T 10-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4G23_RS15365 b826a2ce804ffdf6cb7a6d2d31cf3b03 366 SUPERFAMILY SSF46785 280 358 6.21E-19 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS09915 7e684c46905b7e54e0e73afdec2e27d2 335 Pfam PF01944 Stage II sporulation protein M 109 283 5.2E-36 T 10-11-2016 IPR002798 Stage II sporulation protein M-like A4G23_RS08020 a213265a654ff9c09e3a9f52f57e97bf 256 Gene3D G3DSA:1.10.150.320 189 255 1.8E-18 T 10-11-2016 A4G23_RS08020 a213265a654ff9c09e3a9f52f57e97bf 256 Gene3D G3DSA:3.10.560.10 113 161 3.7E-6 T 10-11-2016 A4G23_RS08020 a213265a654ff9c09e3a9f52f57e97bf 256 Pfam PF10531 SLBB domain 113 163 9.9E-12 T 10-11-2016 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS08020 a213265a654ff9c09e3a9f52f57e97bf 256 SUPERFAMILY SSF47781 184 253 1.69E-23 T 10-11-2016 IPR010994 RuvA domain 2-like A4G23_RS08020 a213265a654ff9c09e3a9f52f57e97bf 256 Pfam PF12836 Helix-hairpin-helix motif 194 255 4.8E-21 T 10-11-2016 A4G23_RS09860 14291c3b826a63a707253a0472c2193e 601 SMART SM00304 236 288 8.0E-12 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS09860 14291c3b826a63a707253a0472c2193e 601 SMART SM00387 409 520 3.0E-29 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS09860 14291c3b826a63a707253a0472c2193e 601 Pfam PF00672 HAMP domain 218 285 1.6E-14 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS09860 14291c3b826a63a707253a0472c2193e 601 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 410 519 6.8E-18 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS09860 14291c3b826a63a707253a0472c2193e 601 Gene3D G3DSA:1.10.287.130 287 359 4.2E-16 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS09860 14291c3b826a63a707253a0472c2193e 601 SMART SM00388 296 363 1.1E-16 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS09860 14291c3b826a63a707253a0472c2193e 601 SUPERFAMILY SSF55874 353 522 5.24E-41 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS09860 14291c3b826a63a707253a0472c2193e 601 Pfam PF00512 His Kinase A (phospho-acceptor) domain 296 363 2.7E-13 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS09860 14291c3b826a63a707253a0472c2193e 601 SUPERFAMILY SSF158472 236 286 2.35E-8 T 10-11-2016 A4G23_RS09860 14291c3b826a63a707253a0472c2193e 601 Gene3D G3DSA:3.30.565.10 366 521 3.9E-38 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS09860 14291c3b826a63a707253a0472c2193e 601 PRINTS PR00344 Bacterial sensor protein C-terminal signature 463 473 3.6E-14 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS09860 14291c3b826a63a707253a0472c2193e 601 PRINTS PR00344 Bacterial sensor protein C-terminal signature 445 459 3.6E-14 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS09860 14291c3b826a63a707253a0472c2193e 601 PRINTS PR00344 Bacterial sensor protein C-terminal signature 504 517 3.6E-14 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS09860 14291c3b826a63a707253a0472c2193e 601 PRINTS PR00344 Bacterial sensor protein C-terminal signature 480 498 3.6E-14 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS09860 14291c3b826a63a707253a0472c2193e 601 SUPERFAMILY SSF47384 279 363 1.31E-16 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS02715 74411e8dfbe0f88c3a6dff9df1b5a80c 418 Gene3D G3DSA:1.10.630.10 14 414 1.2E-113 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS02715 74411e8dfbe0f88c3a6dff9df1b5a80c 418 SUPERFAMILY SSF48264 12 400 3.41E-85 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS02715 74411e8dfbe0f88c3a6dff9df1b5a80c 418 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 358 367 - T 10-11-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A4G23_RS02715 74411e8dfbe0f88c3a6dff9df1b5a80c 418 Pfam PF00067 Cytochrome P450 291 383 4.5E-15 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS02715 74411e8dfbe0f88c3a6dff9df1b5a80c 418 Pfam PF00067 Cytochrome P450 212 282 5.0E-6 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS02715 74411e8dfbe0f88c3a6dff9df1b5a80c 418 PRINTS PR00359 B-class P450 signature 356 365 3.2E-49 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS02715 74411e8dfbe0f88c3a6dff9df1b5a80c 418 PRINTS PR00359 B-class P450 signature 147 163 3.2E-49 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS02715 74411e8dfbe0f88c3a6dff9df1b5a80c 418 PRINTS PR00359 B-class P450 signature 101 112 3.2E-49 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS02715 74411e8dfbe0f88c3a6dff9df1b5a80c 418 PRINTS PR00359 B-class P450 signature 164 179 3.2E-49 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS02715 74411e8dfbe0f88c3a6dff9df1b5a80c 418 PRINTS PR00359 B-class P450 signature 209 231 3.2E-49 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS02715 74411e8dfbe0f88c3a6dff9df1b5a80c 418 PRINTS PR00359 B-class P450 signature 335 350 3.2E-49 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS02715 74411e8dfbe0f88c3a6dff9df1b5a80c 418 PRINTS PR00359 B-class P450 signature 365 376 3.2E-49 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS02715 74411e8dfbe0f88c3a6dff9df1b5a80c 418 PRINTS PR00359 B-class P450 signature 307 334 3.2E-49 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS02715 74411e8dfbe0f88c3a6dff9df1b5a80c 418 PRINTS PR00359 B-class P450 signature 290 301 3.2E-49 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS14855 f0a1c94516789896cc4079d75ca47863 399 Pfam PF13365 Trypsin-like peptidase domain 220 358 4.8E-23 T 10-11-2016 A4G23_RS14855 f0a1c94516789896cc4079d75ca47863 399 Gene3D G3DSA:2.40.10.10 219 290 1.6E-13 T 10-11-2016 A4G23_RS14855 f0a1c94516789896cc4079d75ca47863 399 Pfam PF02674 Colicin V production protein 4 149 1.8E-19 T 10-11-2016 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 A4G23_RS14855 f0a1c94516789896cc4079d75ca47863 399 Gene3D G3DSA:2.40.10.10 291 384 2.1E-14 T 10-11-2016 A4G23_RS14855 f0a1c94516789896cc4079d75ca47863 399 SUPERFAMILY SSF50494 196 382 3.87E-35 T 10-11-2016 IPR009003 Peptidase S1, PA clan A4G23_RS14855 f0a1c94516789896cc4079d75ca47863 399 PRINTS PR00834 HtrA/DegQ protease family signature 228 240 6.3E-8 T 10-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4G23_RS14855 f0a1c94516789896cc4079d75ca47863 399 PRINTS PR00834 HtrA/DegQ protease family signature 289 313 6.3E-8 T 10-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4G23_RS14855 f0a1c94516789896cc4079d75ca47863 399 PRINTS PR00834 HtrA/DegQ protease family signature 250 270 6.3E-8 T 10-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4G23_RS14855 f0a1c94516789896cc4079d75ca47863 399 PRINTS PR00834 HtrA/DegQ protease family signature 329 346 6.3E-8 T 10-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4G23_RS12130 17dab4c484a38cbfcb4691749407c27c 377 Gene3D G3DSA:2.40.50.140 285 358 1.1E-9 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS12130 17dab4c484a38cbfcb4691749407c27c 377 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS12130 17dab4c484a38cbfcb4691749407c27c 377 SUPERFAMILY SSF52540 6 245 3.87E-83 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS12130 17dab4c484a38cbfcb4691749407c27c 377 Gene3D G3DSA:2.40.50.100 361 375 4.5E-7 T 10-11-2016 A4G23_RS12130 17dab4c484a38cbfcb4691749407c27c 377 Gene3D G3DSA:2.40.50.100 241 284 4.5E-7 T 10-11-2016 A4G23_RS12130 17dab4c484a38cbfcb4691749407c27c 377 Gene3D G3DSA:3.40.50.300 4 236 8.0E-72 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS12130 17dab4c484a38cbfcb4691749407c27c 377 SMART SM00382 30 213 2.2E-12 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS12130 17dab4c484a38cbfcb4691749407c27c 377 SUPERFAMILY SSF50331 238 375 5.39E-20 T 10-11-2016 IPR008995 Molybdate/tungstate binding, C-terminal A4G23_RS12130 17dab4c484a38cbfcb4691749407c27c 377 Pfam PF00005 ABC transporter 22 163 1.4E-29 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS12130 17dab4c484a38cbfcb4691749407c27c 377 Pfam PF03459 TOBE domain 305 366 3.2E-6 T 10-11-2016 IPR005116 Transport-associated OB, type 1 A4G23_RS14190 8c14b06280bb4c6df4f321243597ca75 423 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 227 415 2.3E-43 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS14190 8c14b06280bb4c6df4f321243597ca75 423 SMART SM00331 200 415 9.9E-30 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS14190 8c14b06280bb4c6df4f321243597ca75 423 SUPERFAMILY SSF55781 12 188 7.63E-36 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS14190 8c14b06280bb4c6df4f321243597ca75 423 Pfam PF13185 GAF domain 30 171 4.2E-15 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS14190 8c14b06280bb4c6df4f321243597ca75 423 Gene3D G3DSA:3.30.450.40 9 179 3.9E-31 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS14190 8c14b06280bb4c6df4f321243597ca75 423 SUPERFAMILY SSF81606 214 415 1.41E-8 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS14190 8c14b06280bb4c6df4f321243597ca75 423 SMART SM00065 30 180 9.9E-17 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS00815 fd9cdfe259341dc73275fe9a479c5d5c 324 SUPERFAMILY SSF55469 113 168 7.14E-8 T 10-11-2016 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4G23_RS00815 fd9cdfe259341dc73275fe9a479c5d5c 324 SUPERFAMILY SSF55469 225 315 7.14E-8 T 10-11-2016 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4G23_RS00815 fd9cdfe259341dc73275fe9a479c5d5c 324 Gene3D G3DSA:3.40.109.10 194 322 1.2E-23 T 10-11-2016 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4G23_RS00815 fd9cdfe259341dc73275fe9a479c5d5c 324 Gene3D G3DSA:3.40.109.10 8 72 1.2E-23 T 10-11-2016 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4G23_RS00815 fd9cdfe259341dc73275fe9a479c5d5c 324 SUPERFAMILY SSF55469 11 95 3.85E-6 T 10-11-2016 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4G23_RS01700 7fb06b1c4e1f9f8288bc3f80753dd455 334 SUPERFAMILY SSF48371 118 328 2.99E-18 T 10-11-2016 IPR016024 Armadillo-type fold GO:0005488 A4G23_RS01700 7fb06b1c4e1f9f8288bc3f80753dd455 334 Pfam PF13646 HEAT repeats 179 262 3.5E-11 T 10-11-2016 A4G23_RS01700 7fb06b1c4e1f9f8288bc3f80753dd455 334 Pfam PF13411 MerR HTH family regulatory protein 3 68 5.1E-15 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS01700 7fb06b1c4e1f9f8288bc3f80753dd455 334 SUPERFAMILY SSF46955 3 102 6.23E-24 T 10-11-2016 IPR009061 Putative DNA-binding domain A4G23_RS01700 7fb06b1c4e1f9f8288bc3f80753dd455 334 Gene3D G3DSA:1.25.10.10 118 328 2.4E-17 T 10-11-2016 IPR011989 Armadillo-like helical A4G23_RS01700 7fb06b1c4e1f9f8288bc3f80753dd455 334 Gene3D G3DSA:1.10.1660.10 3 101 2.0E-26 T 10-11-2016 A4G23_RS01700 7fb06b1c4e1f9f8288bc3f80753dd455 334 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS01700 7fb06b1c4e1f9f8288bc3f80753dd455 334 SMART SM00567 E-Z type HEAT repeats 189 218 0.0083 T 10-11-2016 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 A4G23_RS01700 7fb06b1c4e1f9f8288bc3f80753dd455 334 SMART SM00567 E-Z type HEAT repeats 220 249 84.0 T 10-11-2016 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 A4G23_RS01700 7fb06b1c4e1f9f8288bc3f80753dd455 334 SMART SM00567 E-Z type HEAT repeats 159 187 800.0 T 10-11-2016 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 A4G23_RS01700 7fb06b1c4e1f9f8288bc3f80753dd455 334 SMART SM00567 E-Z type HEAT repeats 287 316 3.9 T 10-11-2016 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 A4G23_RS01700 7fb06b1c4e1f9f8288bc3f80753dd455 334 SMART SM00422 1 70 5.7E-22 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS01700 7fb06b1c4e1f9f8288bc3f80753dd455 334 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 5.8E-7 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS01700 7fb06b1c4e1f9f8288bc3f80753dd455 334 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 5.8E-7 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS01700 7fb06b1c4e1f9f8288bc3f80753dd455 334 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 5.8E-7 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS22820 acb98dcea4e3544b0d238744771b1536 253 Gene3D G3DSA:3.30.70.1200 1 81 6.8E-22 T 10-11-2016 A4G23_RS22820 acb98dcea4e3544b0d238744771b1536 253 Gene3D G3DSA:3.30.70.1210 99 251 1.5E-31 T 10-11-2016 A4G23_RS22820 acb98dcea4e3544b0d238744771b1536 253 SUPERFAMILY SSF117987 99 251 1.75E-26 T 10-11-2016 A4G23_RS22820 acb98dcea4e3544b0d238744771b1536 253 TIGRFAM TIGR01907 casE_Cse3: CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI 93 251 3.5E-13 T 10-11-2016 IPR010179 CRISPR-associated protein Cse3 A4G23_RS22820 acb98dcea4e3544b0d238744771b1536 253 SMART SM01101 1 251 6.5E-64 T 10-11-2016 IPR010179 CRISPR-associated protein Cse3 A4G23_RS22820 acb98dcea4e3544b0d238744771b1536 253 Pfam PF08798 CRISPR associated protein 1 251 1.2E-57 T 10-11-2016 IPR010179 CRISPR-associated protein Cse3 A4G23_RS22820 acb98dcea4e3544b0d238744771b1536 253 SUPERFAMILY SSF117987 1 84 5.23E-21 T 10-11-2016 A4G23_RS13340 3e7724c69dcb336df4f4a00fd7882daa 480 Pfam PF01098 Cell cycle protein 82 459 4.6E-76 T 10-11-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 A4G23_RS27290 af63edeb19975c627d9daf4952782433 260 PRINTS PR00599 Methionine aminopeptidase-1 signature 166 178 1.0E-13 T 10-11-2016 IPR001714 Peptidase M24, methionine aminopeptidase A4G23_RS27290 af63edeb19975c627d9daf4952782433 260 PRINTS PR00599 Methionine aminopeptidase-1 signature 197 209 1.0E-13 T 10-11-2016 IPR001714 Peptidase M24, methionine aminopeptidase A4G23_RS27290 af63edeb19975c627d9daf4952782433 260 PRINTS PR00599 Methionine aminopeptidase-1 signature 95 111 1.0E-13 T 10-11-2016 IPR001714 Peptidase M24, methionine aminopeptidase A4G23_RS27290 af63edeb19975c627d9daf4952782433 260 PRINTS PR00599 Methionine aminopeptidase-1 signature 73 86 1.0E-13 T 10-11-2016 IPR001714 Peptidase M24, methionine aminopeptidase A4G23_RS27290 af63edeb19975c627d9daf4952782433 260 Hamap MF_01974 Methionine aminopeptidase [map]. 2 255 30.178 T 10-11-2016 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 A4G23_RS27290 af63edeb19975c627d9daf4952782433 260 Gene3D G3DSA:3.90.230.10 7 254 9.1E-59 T 10-11-2016 IPR000994 Peptidase M24, structural domain A4G23_RS27290 af63edeb19975c627d9daf4952782433 260 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 2 253 8.1E-62 T 10-11-2016 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 A4G23_RS27290 af63edeb19975c627d9daf4952782433 260 SUPERFAMILY SSF55920 2 253 1.23E-61 T 10-11-2016 IPR000994 Peptidase M24, structural domain A4G23_RS27290 af63edeb19975c627d9daf4952782433 260 Pfam PF00557 Metallopeptidase family M24 13 246 2.9E-36 T 10-11-2016 IPR000994 Peptidase M24, structural domain A4G23_RS20455 079e46e4bbae730c93ec9794b7adf228 410 SMART SM00962 208 407 6.5E-105 T 10-11-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A4G23_RS20455 079e46e4bbae730c93ec9794b7adf228 410 SUPERFAMILY SSF52540 206 407 9.72E-49 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS20455 079e46e4bbae730c93ec9794b7adf228 410 Gene3D G3DSA:3.40.50.300 220 407 5.4E-73 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS20455 079e46e4bbae730c93ec9794b7adf228 410 Pfam PF00448 SRP54-type protein, GTPase domain 209 406 1.2E-72 T 10-11-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A4G23_RS20455 079e46e4bbae730c93ec9794b7adf228 410 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 134 407 58.343 T 10-11-2016 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 A4G23_RS20455 079e46e4bbae730c93ec9794b7adf228 410 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 380 393 - T 10-11-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A4G23_RS20455 079e46e4bbae730c93ec9794b7adf228 410 SMART SM00382 207 383 5.8E-9 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS20455 079e46e4bbae730c93ec9794b7adf228 410 Gene3D G3DSA:1.20.120.140 136 219 1.4E-26 T 10-11-2016 A4G23_RS20455 079e46e4bbae730c93ec9794b7adf228 410 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 135 405 3.7E-101 T 10-11-2016 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 A4G23_RS20455 079e46e4bbae730c93ec9794b7adf228 410 SUPERFAMILY SSF47364 107 185 6.02E-19 T 10-11-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A4G23_RS20455 079e46e4bbae730c93ec9794b7adf228 410 Pfam PF02881 SRP54-type protein, helical bundle domain 122 187 2.1E-13 T 10-11-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A4G23_RS20455 079e46e4bbae730c93ec9794b7adf228 410 SMART SM00963 111 191 9.3E-23 T 10-11-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A4G23_RS07705 663871ec69b1fb498a55e9d29d70e2da 296 Pfam PF00797 N-acetyltransferase 28 287 5.0E-61 T 10-11-2016 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 A4G23_RS07705 663871ec69b1fb498a55e9d29d70e2da 296 PRINTS PR01543 Arylamine N-acetyltransferase signature 73 95 2.3E-10 T 10-11-2016 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 A4G23_RS07705 663871ec69b1fb498a55e9d29d70e2da 296 PRINTS PR01543 Arylamine N-acetyltransferase signature 49 72 2.3E-10 T 10-11-2016 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 A4G23_RS07705 663871ec69b1fb498a55e9d29d70e2da 296 PRINTS PR01543 Arylamine N-acetyltransferase signature 278 291 2.3E-10 T 10-11-2016 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 A4G23_RS07705 663871ec69b1fb498a55e9d29d70e2da 296 PRINTS PR01543 Arylamine N-acetyltransferase signature 25 48 2.3E-10 T 10-11-2016 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 A4G23_RS07705 663871ec69b1fb498a55e9d29d70e2da 296 Gene3D G3DSA:3.30.2140.10 215 290 3.2E-52 T 10-11-2016 A4G23_RS07705 663871ec69b1fb498a55e9d29d70e2da 296 Gene3D G3DSA:3.30.2140.10 6 89 3.2E-52 T 10-11-2016 A4G23_RS07705 663871ec69b1fb498a55e9d29d70e2da 296 SUPERFAMILY SSF54001 200 291 2.35E-65 T 10-11-2016 A4G23_RS07705 663871ec69b1fb498a55e9d29d70e2da 296 SUPERFAMILY SSF54001 6 160 2.35E-65 T 10-11-2016 A4G23_RS13585 2a336fa869cb8fd6f30850a96d8cc64b 372 SUPERFAMILY SSF55729 5 114 6.36E-34 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS13585 2a336fa869cb8fd6f30850a96d8cc64b 372 SUPERFAMILY SSF55729 143 194 6.36E-34 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS13585 2a336fa869cb8fd6f30850a96d8cc64b 372 SUPERFAMILY SSF55729 183 365 2.75E-37 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS13585 2a336fa869cb8fd6f30850a96d8cc64b 372 Gene3D G3DSA:3.40.630.30 185 346 4.7E-53 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS13585 2a336fa869cb8fd6f30850a96d8cc64b 372 Gene3D G3DSA:3.40.630.30 148 184 2.2E-54 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS13585 2a336fa869cb8fd6f30850a96d8cc64b 372 Gene3D G3DSA:3.40.630.30 1 116 2.2E-54 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS13585 2a336fa869cb8fd6f30850a96d8cc64b 372 Pfam PF02388 FemAB family 265 365 3.2E-18 T 10-11-2016 IPR003447 FemABX peptidyl transferase GO:0009252|GO:0016755 A4G23_RS13585 2a336fa869cb8fd6f30850a96d8cc64b 372 Pfam PF02388 FemAB family 8 248 1.6E-27 T 10-11-2016 IPR003447 FemABX peptidyl transferase GO:0009252|GO:0016755 A4G23_RS19865 2a493496ebe796366d47b5fc2d735989 607 Gene3D G3DSA:3.40.50.300 366 592 6.3E-78 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS19865 2a493496ebe796366d47b5fc2d735989 607 Pfam PF00005 ABC transporter 385 531 2.4E-31 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS19865 2a493496ebe796366d47b5fc2d735989 607 Pfam PF00664 ABC transporter transmembrane region 41 307 1.5E-28 T 10-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A4G23_RS19865 2a493496ebe796366d47b5fc2d735989 607 ProSitePatterns PS00211 ABC transporters family signature. 503 517 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS19865 2a493496ebe796366d47b5fc2d735989 607 SUPERFAMILY SSF52540 363 600 3.02E-82 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS19865 2a493496ebe796366d47b5fc2d735989 607 SMART SM00382 391 577 4.4E-19 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS19865 2a493496ebe796366d47b5fc2d735989 607 SUPERFAMILY SSF90123 28 348 3.01E-62 T 10-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A4G23_RS19865 2a493496ebe796366d47b5fc2d735989 607 Gene3D G3DSA:1.20.1560.10 28 346 2.4E-74 T 10-11-2016 A4G23_RS13635 4f214493e8016da7d268b1b6f093ff04 150 Pfam PF00583 Acetyltransferase (GNAT) family 58 140 4.7E-15 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS13635 4f214493e8016da7d268b1b6f093ff04 150 SUPERFAMILY SSF55729 1 144 6.81E-30 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS13635 4f214493e8016da7d268b1b6f093ff04 150 Gene3D G3DSA:3.40.630.30 1 149 8.5E-45 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS04580 c966bd09ddb85506b2e87d9371d9309e 150 Pfam PF09278 MerR, DNA binding 53 118 7.9E-19 T 10-11-2016 IPR015358 Transcription regulator MerR, DNA binding A4G23_RS04580 c966bd09ddb85506b2e87d9371d9309e 150 SUPERFAMILY SSF46955 11 131 1.14E-27 T 10-11-2016 IPR009061 Putative DNA-binding domain A4G23_RS04580 c966bd09ddb85506b2e87d9371d9309e 150 SMART SM00422 11 79 2.4E-24 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS04580 c966bd09ddb85506b2e87d9371d9309e 150 Pfam PF00376 MerR family regulatory protein 12 48 6.2E-11 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS04580 c966bd09ddb85506b2e87d9371d9309e 150 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 12 23 3.7E-13 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS04580 c966bd09ddb85506b2e87d9371d9309e 150 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 23 36 3.7E-13 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS04580 c966bd09ddb85506b2e87d9371d9309e 150 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 46 66 3.7E-13 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS04580 c966bd09ddb85506b2e87d9371d9309e 150 TIGRFAM TIGR01950 SoxR: redox-sensitive transcriptional activator SoxR 10 148 6.2E-71 T 10-11-2016 IPR010211 Redox-sensitive transcriptional activator SoxR GO:0003677|GO:0006355|GO:0006979|GO:0051537 A4G23_RS04580 c966bd09ddb85506b2e87d9371d9309e 150 Gene3D G3DSA:1.10.1660.10 11 64 9.2E-20 T 10-11-2016 A4G23_RS04580 c966bd09ddb85506b2e87d9371d9309e 150 Gene3D G3DSA:1.10.1660.10 65 136 5.0E-17 T 10-11-2016 A4G23_RS26975 188c6cfb1ae598dec361b4e0257bd93d 414 Gene3D G3DSA:3.40.50.2000 234 396 1.2E-10 T 10-11-2016 A4G23_RS26975 188c6cfb1ae598dec361b4e0257bd93d 414 SUPERFAMILY SSF53756 153 407 4.85E-15 T 10-11-2016 A4G23_RS26975 188c6cfb1ae598dec361b4e0257bd93d 414 Pfam PF06925 Monogalactosyldiacylglycerol (MGDG) synthase 146 223 2.1E-14 T 10-11-2016 IPR009695 Diacylglycerol glucosyltransferase, N-terminal GO:0009247|GO:0016758 A4G23_RS17825 850a636bbe726361627da3f5a290245b 187 SUPERFAMILY SSF48498 82 186 1.63E-14 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS17825 850a636bbe726361627da3f5a290245b 187 Gene3D G3DSA:1.10.357.10 6 186 3.5E-42 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS17825 850a636bbe726361627da3f5a290245b 187 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 2.9E-8 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS17825 850a636bbe726361627da3f5a290245b 187 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 2.9E-8 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS17825 850a636bbe726361627da3f5a290245b 187 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 63 6.7E-14 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS17825 850a636bbe726361627da3f5a290245b 187 SUPERFAMILY SSF46689 4 84 4.3E-18 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS16050 4db72029a4b2667ca766ea34338a2ff5 184 Gene3D G3DSA:3.40.50.700 25 149 3.4E-33 T 10-11-2016 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16050 4db72029a4b2667ca766ea34338a2ff5 184 SUPERFAMILY SSF56770 9 154 1.44E-65 T 10-11-2016 A4G23_RS16050 4db72029a4b2667ca766ea34338a2ff5 184 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 11 152 7.5E-70 T 10-11-2016 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16050 4db72029a4b2667ca766ea34338a2ff5 184 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 118 134 - T 10-11-2016 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16050 4db72029a4b2667ca766ea34338a2ff5 184 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 1 151 42.438 T 10-11-2016 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16050 4db72029a4b2667ca766ea34338a2ff5 184 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 37 146 1.7E-24 T 10-11-2016 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS08845 d1f829440d09b70cc52ef04f7d6d5f03 1245 SUPERFAMILY SSF52540 992 1236 2.21E-83 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS08845 d1f829440d09b70cc52ef04f7d6d5f03 1245 ProSitePatterns PS00211 ABC transporters family signature. 484 498 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS08845 d1f829440d09b70cc52ef04f7d6d5f03 1245 Gene3D G3DSA:1.20.1560.10 1 309 1.7E-67 T 10-11-2016 A4G23_RS08845 d1f829440d09b70cc52ef04f7d6d5f03 1245 Gene3D G3DSA:1.20.1560.10 674 988 5.2E-76 T 10-11-2016 A4G23_RS08845 d1f829440d09b70cc52ef04f7d6d5f03 1245 SMART SM00382 372 558 8.3E-14 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS08845 d1f829440d09b70cc52ef04f7d6d5f03 1245 SMART SM00382 1027 1213 2.3E-19 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS08845 d1f829440d09b70cc52ef04f7d6d5f03 1245 Gene3D G3DSA:3.40.50.300 1002 1232 1.1E-78 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS08845 d1f829440d09b70cc52ef04f7d6d5f03 1245 Gene3D G3DSA:3.40.50.300 326 575 4.5E-77 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS08845 d1f829440d09b70cc52ef04f7d6d5f03 1245 Pfam PF00664 ABC transporter transmembrane region 13 281 1.0E-34 T 10-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A4G23_RS08845 d1f829440d09b70cc52ef04f7d6d5f03 1245 Pfam PF00664 ABC transporter transmembrane region 685 956 2.7E-39 T 10-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A4G23_RS08845 d1f829440d09b70cc52ef04f7d6d5f03 1245 SUPERFAMILY SSF90123 1 313 9.81E-69 T 10-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A4G23_RS08845 d1f829440d09b70cc52ef04f7d6d5f03 1245 Pfam PF00005 ABC transporter 363 512 1.8E-29 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS08845 d1f829440d09b70cc52ef04f7d6d5f03 1245 Pfam PF00005 ABC transporter 1019 1167 1.1E-31 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS08845 d1f829440d09b70cc52ef04f7d6d5f03 1245 SUPERFAMILY SSF52540 324 579 1.08E-82 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS08845 d1f829440d09b70cc52ef04f7d6d5f03 1245 SUPERFAMILY SSF90123 674 987 1.27E-71 T 10-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A4G23_RS09280 94419b764b0b3b184c27d6b604797d6d 327 SMART SM00244 97 260 0.0019 T 10-11-2016 IPR001107 Band 7 domain A4G23_RS09280 94419b764b0b3b184c27d6b604797d6d 327 SUPERFAMILY SSF117892 136 266 7.85E-9 T 10-11-2016 IPR001107 Band 7 domain A4G23_RS09280 94419b764b0b3b184c27d6b604797d6d 327 Pfam PF01145 SPFH domain / Band 7 family 104 269 5.9E-19 T 10-11-2016 IPR001107 Band 7 domain A4G23_RS00850 428d4c2b3b18b6b70b549640f9a976f8 298 PIRSF PIRSF001365 4 297 6.7E-69 T 10-11-2016 IPR002220 DapA-like GO:0008152|GO:0016829 A4G23_RS00850 428d4c2b3b18b6b70b549640f9a976f8 298 PRINTS PR00146 Dihydrodipicolinate synthase signature 41 62 3.7E-11 T 10-11-2016 IPR002220 DapA-like GO:0008152|GO:0016829 A4G23_RS00850 428d4c2b3b18b6b70b549640f9a976f8 298 PRINTS PR00146 Dihydrodipicolinate synthase signature 77 95 3.7E-11 T 10-11-2016 IPR002220 DapA-like GO:0008152|GO:0016829 A4G23_RS00850 428d4c2b3b18b6b70b549640f9a976f8 298 PRINTS PR00146 Dihydrodipicolinate synthase signature 109 125 3.7E-11 T 10-11-2016 IPR002220 DapA-like GO:0008152|GO:0016829 A4G23_RS00850 428d4c2b3b18b6b70b549640f9a976f8 298 PRINTS PR00146 Dihydrodipicolinate synthase signature 133 150 3.7E-11 T 10-11-2016 IPR002220 DapA-like GO:0008152|GO:0016829 A4G23_RS00850 428d4c2b3b18b6b70b549640f9a976f8 298 SMART SM01130 7 293 1.4E-82 T 10-11-2016 IPR002220 DapA-like GO:0008152|GO:0016829 A4G23_RS00850 428d4c2b3b18b6b70b549640f9a976f8 298 SUPERFAMILY SSF51569 4 291 5.65E-77 T 10-11-2016 A4G23_RS00850 428d4c2b3b18b6b70b549640f9a976f8 298 Pfam PF00701 Dihydrodipicolinate synthetase family 9 290 8.4E-44 T 10-11-2016 IPR002220 DapA-like GO:0008152|GO:0016829 A4G23_RS00850 428d4c2b3b18b6b70b549640f9a976f8 298 Gene3D G3DSA:3.20.20.70 3 292 7.2E-84 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS25290 40e7860946f78a575ed8f173f9e17651 366 SUPERFAMILY SSF53756 20 312 3.69E-11 T 10-11-2016 A4G23_RS25290 40e7860946f78a575ed8f173f9e17651 366 Gene3D G3DSA:3.40.50.2000 196 289 3.0E-4 T 10-11-2016 A4G23_RS04045 45e05a8e641c996cffd8ff26855792c2 255 SMART SM00421 189 246 4.5E-22 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS04045 45e05a8e641c996cffd8ff26855792c2 255 SUPERFAMILY SSF46894 185 252 1.39E-19 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS04045 45e05a8e641c996cffd8ff26855792c2 255 Gene3D G3DSA:1.10.10.10 191 251 1.3E-23 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS04045 45e05a8e641c996cffd8ff26855792c2 255 Pfam PF00196 Bacterial regulatory proteins, luxR family 192 246 3.4E-17 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS04045 45e05a8e641c996cffd8ff26855792c2 255 Gene3D G3DSA:3.30.450.80 35 190 4.8E-6 T 10-11-2016 IPR005143 Transcription factor LuxR-like, autoinducer-binding domain A4G23_RS04045 45e05a8e641c996cffd8ff26855792c2 255 SUPERFAMILY SSF55781 33 170 1.77E-6 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS04045 45e05a8e641c996cffd8ff26855792c2 255 ProSitePatterns PS00622 LuxR-type HTH domain signature. 206 233 - T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS04045 45e05a8e641c996cffd8ff26855792c2 255 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 206 222 3.0E-13 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS04045 45e05a8e641c996cffd8ff26855792c2 255 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 192 206 3.0E-13 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS04045 45e05a8e641c996cffd8ff26855792c2 255 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 222 234 3.0E-13 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS14250 48a8fb063b853ff34ba43723ea552572 215 Gene3D G3DSA:2.30.110.10 1 206 5.9E-37 T 10-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 A4G23_RS14250 48a8fb063b853ff34ba43723ea552572 215 SUPERFAMILY SSF50475 11 190 2.55E-30 T 10-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 A4G23_RS14250 48a8fb063b853ff34ba43723ea552572 215 Pfam PF04299 Putative FMN-binding domain 1 164 6.1E-24 T 10-11-2016 IPR007396 Transcriptional regulator PAI 2-type A4G23_RS06700 c7f54abb1ea5f22fd0665cfda7383461 209 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 73 8.4E-17 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS06700 c7f54abb1ea5f22fd0665cfda7383461 209 Pfam PF07729 FCD domain 84 193 3.6E-18 T 10-11-2016 IPR011711 GntR, C-terminal A4G23_RS06700 c7f54abb1ea5f22fd0665cfda7383461 209 Gene3D G3DSA:1.20.120.530 76 193 1.8E-20 T 10-11-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal A4G23_RS06700 c7f54abb1ea5f22fd0665cfda7383461 209 Gene3D G3DSA:1.10.10.10 9 74 1.4E-23 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS06700 c7f54abb1ea5f22fd0665cfda7383461 209 SMART SM00895 83 204 1.1E-10 T 10-11-2016 IPR011711 GntR, C-terminal A4G23_RS06700 c7f54abb1ea5f22fd0665cfda7383461 209 SUPERFAMILY SSF48008 80 194 1.31E-19 T 10-11-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal A4G23_RS06700 c7f54abb1ea5f22fd0665cfda7383461 209 SMART SM00345 15 73 1.1E-14 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS06700 c7f54abb1ea5f22fd0665cfda7383461 209 SUPERFAMILY SSF46785 10 101 7.77E-20 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS18490 6c8a3981c0dd958fa883f3fda94e8556 278 Pfam PF13369 Transglutaminase-like superfamily 66 194 1.4E-41 T 10-11-2016 IPR032698 Protein SirB1, N-terminal A4G23_RS18490 6c8a3981c0dd958fa883f3fda94e8556 278 Pfam PF13371 Tetratricopeptide repeat 196 277 1.1E-13 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS12715 b8741fa35ee90e94946769f3d93edd45 453 SUPERFAMILY SSF51905 17 235 1.94E-25 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS12715 b8741fa35ee90e94946769f3d93edd45 453 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 18 353 5.4E-42 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS12715 b8741fa35ee90e94946769f3d93edd45 453 SUPERFAMILY SSF51905 14 77 2.09E-20 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS12715 b8741fa35ee90e94946769f3d93edd45 453 SUPERFAMILY SSF51905 162 400 2.09E-20 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS12715 b8741fa35ee90e94946769f3d93edd45 453 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 185 203 2.2E-9 T 10-11-2016 A4G23_RS12715 b8741fa35ee90e94946769f3d93edd45 453 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 125 143 2.2E-9 T 10-11-2016 A4G23_RS12715 b8741fa35ee90e94946769f3d93edd45 453 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 19 38 2.2E-9 T 10-11-2016 A4G23_RS12715 b8741fa35ee90e94946769f3d93edd45 453 Gene3D G3DSA:3.50.50.60 17 132 5.0E-19 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS12715 b8741fa35ee90e94946769f3d93edd45 453 Gene3D G3DSA:3.50.50.60 133 361 8.1E-28 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS09725 9fe5913709d2a4a920de64ae5be32558 305 Pfam PF02687 FtsX-like permease family 183 304 4.7E-13 T 10-11-2016 IPR003838 ABC transporter permease protein domain GO:0016020 A4G23_RS09725 9fe5913709d2a4a920de64ae5be32558 305 PIRSF PIRSF003097 1 305 4.3E-70 T 10-11-2016 IPR004513 Cell division protein FtsX GO:0007049|GO:0016021 A4G23_RS13945 00b16d554570a4335c1af5e6224ba086 284 Gene3D G3DSA:1.10.10.10 131 186 6.3E-21 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS13945 00b16d554570a4335c1af5e6224ba086 284 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 58 280 1.9E-94 T 10-11-2016 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS13945 00b16d554570a4335c1af5e6224ba086 284 Gene3D G3DSA:1.10.601.10 49 130 2.8E-24 T 10-11-2016 A4G23_RS13945 00b16d554570a4335c1af5e6224ba086 284 Gene3D G3DSA:1.10.10.10 222 281 7.2E-10 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS13945 00b16d554570a4335c1af5e6224ba086 284 Pfam PF04545 Sigma-70, region 4 230 279 7.4E-18 T 10-11-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS13945 00b16d554570a4335c1af5e6224ba086 284 Pfam PF04539 Sigma-70 region 3 144 209 5.6E-11 T 10-11-2016 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS13945 00b16d554570a4335c1af5e6224ba086 284 PRINTS PR00046 Major sigma-70 factor signature 251 266 5.1E-10 T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS13945 00b16d554570a4335c1af5e6224ba086 284 PRINTS PR00046 Major sigma-70 factor signature 234 246 5.1E-10 T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS13945 00b16d554570a4335c1af5e6224ba086 284 PRINTS PR00046 Major sigma-70 factor signature 87 100 5.1E-10 T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS13945 00b16d554570a4335c1af5e6224ba086 284 SUPERFAMILY SSF88946 49 132 3.01E-30 T 10-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS13945 00b16d554570a4335c1af5e6224ba086 284 SUPERFAMILY SSF88659 199 281 6.92E-17 T 10-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS13945 00b16d554570a4335c1af5e6224ba086 284 SUPERFAMILY SSF88659 136 211 6.1E-14 T 10-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS13945 00b16d554570a4335c1af5e6224ba086 284 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 87 100 - T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS13945 00b16d554570a4335c1af5e6224ba086 284 Pfam PF04542 Sigma-70 region 2 63 132 1.3E-17 T 10-11-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS13945 00b16d554570a4335c1af5e6224ba086 284 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 60 280 6.9E-36 T 10-11-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS20915 e7201ae6af4d8b5db8271c9115452b3b 1714 SUPERFAMILY SSF52540 251 293 1.32E-7 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS20915 e7201ae6af4d8b5db8271c9115452b3b 1714 SUPERFAMILY SSF52540 324 379 1.32E-7 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS20915 e7201ae6af4d8b5db8271c9115452b3b 1714 SUPERFAMILY SSF50494 8 161 1.93E-5 T 10-11-2016 IPR009003 Peptidase S1, PA clan A4G23_RS20915 e7201ae6af4d8b5db8271c9115452b3b 1714 Gene3D G3DSA:3.40.50.300 252 380 4.9E-4 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS00705 8558e8c5d5f50cb6d5a92d2e395108fa 354 Pfam PF13556 PucR C-terminal helix-turn-helix domain 285 341 1.3E-16 T 10-11-2016 IPR025736 PucR C-terminal helix-turn-helix domain A4G23_RS20185 593a9bbe35813428662096fdfb1cba0f 337 SUPERFAMILY SSF55909 1 336 4.46E-116 T 10-11-2016 A4G23_RS20185 593a9bbe35813428662096fdfb1cba0f 337 Gene3D G3DSA:3.75.10.10 2 336 4.0E-120 T 10-11-2016 A4G23_RS20185 593a9bbe35813428662096fdfb1cba0f 337 Pfam PF04371 Porphyromonas-type peptidyl-arginine deiminase 4 335 1.3E-108 T 10-11-2016 IPR007466 Peptidyl-arginine deiminase, Porphyromonas-type GO:0004668|GO:0009446 KEGG: 00330+3.5.3.12|MetaCyc: PWY-43 A4G23_RS20325 7a81090feaaf2ac0792237d41f2f2789 197 Gene3D G3DSA:3.20.19.10 1 187 8.1E-42 T 10-11-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel A4G23_RS20325 7a81090feaaf2ac0792237d41f2f2789 197 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 180 2.9E-57 T 10-11-2016 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 A4G23_RS20325 7a81090feaaf2ac0792237d41f2f2789 197 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 191 40.379 T 10-11-2016 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 A4G23_RS20325 7a81090feaaf2ac0792237d41f2f2789 197 Pfam PF00694 Aconitase C-terminal domain 1 117 1.8E-25 T 10-11-2016 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 A4G23_RS20325 7a81090feaaf2ac0792237d41f2f2789 197 SUPERFAMILY SSF52016 1 187 7.06E-53 T 10-11-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel A4G23_RS26430 4f1bdf6c64b90f477885afd97a515fc6 141 SUPERFAMILY SSF46689 8 56 1.55E-10 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS26430 4f1bdf6c64b90f477885afd97a515fc6 141 Pfam PF12833 Helix-turn-helix domain 29 108 5.4E-23 T 10-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4G23_RS26430 4f1bdf6c64b90f477885afd97a515fc6 141 Gene3D G3DSA:1.10.10.60 8 61 1.6E-16 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS26430 4f1bdf6c64b90f477885afd97a515fc6 141 SUPERFAMILY SSF46689 59 109 1.25E-11 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS26430 4f1bdf6c64b90f477885afd97a515fc6 141 Gene3D G3DSA:1.10.10.60 62 111 1.2E-14 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS26430 4f1bdf6c64b90f477885afd97a515fc6 141 SMART SM00342 23 106 4.4E-31 T 10-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4G23_RS19520 66523ac34caec1f813c92030b7276b12 215 Gene3D G3DSA:3.90.870.10 5 205 2.3E-64 T 10-11-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain A4G23_RS19520 66523ac34caec1f813c92030b7276b12 215 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 12 207 9.6E-57 T 10-11-2016 IPR006070 YrdC-like domain GO:0003725 A4G23_RS19520 66523ac34caec1f813c92030b7276b12 215 Pfam PF01300 Telomere recombination 23 197 1.1E-45 T 10-11-2016 IPR006070 YrdC-like domain GO:0003725 A4G23_RS19520 66523ac34caec1f813c92030b7276b12 215 SUPERFAMILY SSF55821 2 210 2.66E-57 T 10-11-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain A4G23_RS22845 ea00f8c0db934836591245649ab52e0a 509 SUPERFAMILY SSF47413 4 65 1.42E-14 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS22845 ea00f8c0db934836591245649ab52e0a 509 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 80 496 8.6E-39 T 10-11-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 A4G23_RS22845 ea00f8c0db934836591245649ab52e0a 509 SUPERFAMILY SSF55205 74 506 5.23E-94 T 10-11-2016 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 A4G23_RS22845 ea00f8c0db934836591245649ab52e0a 509 SMART SM00530 12 67 5.8E-13 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS22845 ea00f8c0db934836591245649ab52e0a 509 Pfam PF01381 Helix-turn-helix 13 63 5.2E-12 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS22845 ea00f8c0db934836591245649ab52e0a 509 Gene3D G3DSA:1.10.260.40 3 66 1.8E-19 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS22845 ea00f8c0db934836591245649ab52e0a 509 Gene3D G3DSA:3.65.10.10 292 504 2.0E-37 T 10-11-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 A4G23_RS22845 ea00f8c0db934836591245649ab52e0a 509 Gene3D G3DSA:3.65.10.10 92 291 8.5E-40 T 10-11-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 A4G23_RS03725 da70ae471a492ec3768186c1d49ea0f5 201 SUPERFAMILY SSF47781 66 131 4.45E-18 T 10-11-2016 IPR010994 RuvA domain 2-like A4G23_RS03725 da70ae471a492ec3768186c1d49ea0f5 201 SUPERFAMILY SSF46929 147 199 1.2E-9 T 10-11-2016 IPR011114 DNA helicase, Holliday junction RuvA type, domain III, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 A4G23_RS03725 da70ae471a492ec3768186c1d49ea0f5 201 Gene3D G3DSA:1.10.8.10 140 201 5.2E-13 T 10-11-2016 A4G23_RS03725 da70ae471a492ec3768186c1d49ea0f5 201 Gene3D G3DSA:1.10.150.20 68 133 2.3E-25 T 10-11-2016 A4G23_RS03725 da70ae471a492ec3768186c1d49ea0f5 201 Pfam PF01330 RuvA N terminal domain 1 61 2.4E-19 T 10-11-2016 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 A4G23_RS03725 da70ae471a492ec3768186c1d49ea0f5 201 Gene3D G3DSA:2.40.50.140 1 64 1.4E-22 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS03725 da70ae471a492ec3768186c1d49ea0f5 201 Pfam PF07499 RuvA, C-terminal domain 148 197 2.6E-10 T 10-11-2016 IPR011114 DNA helicase, Holliday junction RuvA type, domain III, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 A4G23_RS03725 da70ae471a492ec3768186c1d49ea0f5 201 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 181 1.2E-36 T 10-11-2016 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 A4G23_RS03725 da70ae471a492ec3768186c1d49ea0f5 201 Pfam PF14520 Helix-hairpin-helix domain 71 129 3.5E-16 T 10-11-2016 A4G23_RS03725 da70ae471a492ec3768186c1d49ea0f5 201 SMART SM00278 72 91 50.0 T 10-11-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A4G23_RS03725 da70ae471a492ec3768186c1d49ea0f5 201 SMART SM00278 107 126 0.05 T 10-11-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A4G23_RS03725 da70ae471a492ec3768186c1d49ea0f5 201 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 198 26.702 T 10-11-2016 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 A4G23_RS03725 da70ae471a492ec3768186c1d49ea0f5 201 SUPERFAMILY SSF50249 1 62 4.57E-14 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS11080 f31bb05f74091d065367d948fc89cb91 745 Pfam PF02342 TerD domain 595 740 2.5E-21 T 10-11-2016 IPR003325 TerD domain GO:0006950 A4G23_RS11080 f31bb05f74091d065367d948fc89cb91 745 Pfam PF04471 Restriction endonuclease 387 498 4.5E-28 T 10-11-2016 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 A4G23_RS11080 f31bb05f74091d065367d948fc89cb91 745 Gene3D G3DSA:3.40.1350.10 383 500 6.5E-21 T 10-11-2016 IPR011856 tRNA endonuclease-like domain GO:0003676|GO:0004518 Reactome: R-HSA-6784531 A4G23_RS11080 f31bb05f74091d065367d948fc89cb91 745 Gene3D G3DSA:2.60.60.30 595 737 2.3E-21 T 10-11-2016 A4G23_RS11080 f31bb05f74091d065367d948fc89cb91 745 SUPERFAMILY SSF52980 390 501 8.58E-20 T 10-11-2016 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A4G23_RS17110 eedf907a2cf2f03f88aa8e4ed486530f 563 Gene3D G3DSA:2.70.70.10 412 555 2.4E-41 T 10-11-2016 A4G23_RS17110 eedf907a2cf2f03f88aa8e4ed486530f 563 SUPERFAMILY SSF51261 430 554 1.57E-40 T 10-11-2016 IPR011055 Duplicated hybrid motif A4G23_RS17110 eedf907a2cf2f03f88aa8e4ed486530f 563 Pfam PF01551 Peptidase family M23 457 550 5.1E-28 T 10-11-2016 IPR016047 Peptidase M23 A4G23_RS03150 cd3fdd14d3493e24ed6517bc28dc064c 202 SUPERFAMILY SSF52540 17 194 2.25E-23 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS03150 cd3fdd14d3493e24ed6517bc28dc064c 202 Gene3D G3DSA:3.40.50.300 17 191 3.6E-14 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS03150 cd3fdd14d3493e24ed6517bc28dc064c 202 Pfam PF03029 Conserved hypothetical ATP binding protein 23 191 3.0E-26 T 10-11-2016 IPR004130 GPN-loop GTPase A4G23_RS23045 ea4fc202a656e2ff6f5f348ff99b3004 135 Gene3D G3DSA:2.170.150.20 3 134 1.9E-60 T 10-11-2016 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 A4G23_RS23045 ea4fc202a656e2ff6f5f348ff99b3004 135 Pfam PF01641 SelR domain 11 131 8.0E-53 T 10-11-2016 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 A4G23_RS23045 ea4fc202a656e2ff6f5f348ff99b3004 135 SUPERFAMILY SSF51316 6 134 9.94E-56 T 10-11-2016 IPR011057 Mss4-like A4G23_RS23045 ea4fc202a656e2ff6f5f348ff99b3004 135 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 7 133 1.1E-48 T 10-11-2016 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 A4G23_RS04460 396f51054d3353ae3f72aa885f0f7ee2 444 SUPERFAMILY SSF53187 16 196 3.83E-54 T 10-11-2016 A4G23_RS04460 396f51054d3353ae3f72aa885f0f7ee2 444 SUPERFAMILY SSF53187 354 441 3.83E-54 T 10-11-2016 A4G23_RS04460 396f51054d3353ae3f72aa885f0f7ee2 444 Pfam PF07687 Peptidase dimerisation domain 204 333 7.9E-14 T 10-11-2016 IPR011650 Peptidase M20, dimerisation domain A4G23_RS04460 396f51054d3353ae3f72aa885f0f7ee2 444 Gene3D G3DSA:3.40.630.10 16 216 8.4E-61 T 10-11-2016 A4G23_RS04460 396f51054d3353ae3f72aa885f0f7ee2 444 Gene3D G3DSA:3.40.630.10 379 442 8.4E-61 T 10-11-2016 A4G23_RS04460 396f51054d3353ae3f72aa885f0f7ee2 444 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 86 95 - T 10-11-2016 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 A4G23_RS04460 396f51054d3353ae3f72aa885f0f7ee2 444 Pfam PF01546 Peptidase family M20/M25/M40 87 442 4.7E-37 T 10-11-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A4G23_RS04460 396f51054d3353ae3f72aa885f0f7ee2 444 SUPERFAMILY SSF55031 293 333 3.01E-9 T 10-11-2016 IPR011650 Peptidase M20, dimerisation domain A4G23_RS04460 396f51054d3353ae3f72aa885f0f7ee2 444 SUPERFAMILY SSF55031 207 249 3.01E-9 T 10-11-2016 IPR011650 Peptidase M20, dimerisation domain A4G23_RS04460 396f51054d3353ae3f72aa885f0f7ee2 444 Gene3D G3DSA:3.30.70.360 217 256 6.0E-21 T 10-11-2016 IPR011650 Peptidase M20, dimerisation domain A4G23_RS04460 396f51054d3353ae3f72aa885f0f7ee2 444 Gene3D G3DSA:3.30.70.360 294 335 6.0E-21 T 10-11-2016 IPR011650 Peptidase M20, dimerisation domain A4G23_RS15690 75b5382677dc5ffd0e0e4b61c59f89b2 320 ProSitePatterns PS00894 DeoR-type HTH domain signature. 7 41 - T 10-11-2016 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 A4G23_RS15690 75b5382677dc5ffd0e0e4b61c59f89b2 320 Pfam PF13280 WYL domain 144 313 2.0E-32 T 10-11-2016 IPR026881 WYL domain A4G23_RS15690 75b5382677dc5ffd0e0e4b61c59f89b2 320 Pfam PF08279 HTH domain 7 62 4.8E-16 T 10-11-2016 IPR013196 Helix-turn-helix, type 11 A4G23_RS15690 75b5382677dc5ffd0e0e4b61c59f89b2 320 PIRSF PIRSF016838 1 319 4.6E-25 T 10-11-2016 IPR028349 Protein PafC A4G23_RS15690 75b5382677dc5ffd0e0e4b61c59f89b2 320 Gene3D G3DSA:1.10.10.10 4 66 1.0E-20 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS15690 75b5382677dc5ffd0e0e4b61c59f89b2 320 SUPERFAMILY SSF46785 5 61 1.06E-11 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS01155 929447adb2d74a919328ef79e0375205 438 Gene3D G3DSA:3.30.450.40 1 51 1.4E-11 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS01155 929447adb2d74a919328ef79e0375205 438 SUPERFAMILY SSF55874 350 420 4.59E-8 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS01155 929447adb2d74a919328ef79e0375205 438 SUPERFAMILY SSF55781 1 53 5.89E-7 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS01155 929447adb2d74a919328ef79e0375205 438 Pfam PF13581 Histidine kinase-like ATPase domain 327 430 1.3E-8 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS01155 929447adb2d74a919328ef79e0375205 438 Gene3D G3DSA:3.30.565.10 352 417 0.001 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS01155 929447adb2d74a919328ef79e0375205 438 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 101 309 1.5E-50 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS01155 929447adb2d74a919328ef79e0375205 438 SMART SM00331 71 309 1.2E-36 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS12475 cbcef327b1880a2e977e5be7ff7c90d2 245 Gene3D G3DSA:3.40.50.2300 7 127 1.1E-43 T 10-11-2016 A4G23_RS12475 cbcef327b1880a2e977e5be7ff7c90d2 245 SMART SM00862 164 239 5.5E-27 T 10-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4G23_RS12475 cbcef327b1880a2e977e5be7ff7c90d2 245 Pfam PF00486 Transcriptional regulatory protein, C terminal 164 239 3.7E-26 T 10-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4G23_RS12475 cbcef327b1880a2e977e5be7ff7c90d2 245 SMART SM00448 8 119 8.2E-45 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS12475 cbcef327b1880a2e977e5be7ff7c90d2 245 Pfam PF00072 Response regulator receiver domain 10 120 1.1E-32 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS12475 cbcef327b1880a2e977e5be7ff7c90d2 245 SUPERFAMILY SSF52172 7 197 2.7E-45 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS12475 cbcef327b1880a2e977e5be7ff7c90d2 245 Gene3D G3DSA:1.10.10.10 143 241 3.5E-34 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS17810 1284886380c84da0c310bdaf86f655d4 407 SUPERFAMILY SSF53756 2 401 1.67E-83 T 10-11-2016 A4G23_RS17810 1284886380c84da0c310bdaf86f655d4 407 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 3 124 7.9E-9 T 10-11-2016 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4G23_RS17810 1284886380c84da0c310bdaf86f655d4 407 Gene3D G3DSA:3.40.50.2000 2 235 3.4E-49 T 10-11-2016 A4G23_RS17810 1284886380c84da0c310bdaf86f655d4 407 Gene3D G3DSA:3.40.50.2000 236 379 2.0E-51 T 10-11-2016 A4G23_RS11730 41e70cec197182512b06beb0c41a30aa 448 Pfam PF02378 Phosphotransferase system, EIIC 106 374 2.0E-25 T 10-11-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 A4G23_RS11730 41e70cec197182512b06beb0c41a30aa 448 Gene3D G3DSA:3.30.1360.60 1 68 1.4E-18 T 10-11-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 A4G23_RS11730 41e70cec197182512b06beb0c41a30aa 448 Pfam PF00367 phosphotransferase system, EIIB 1 27 4.7E-10 T 10-11-2016 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 A4G23_RS11730 41e70cec197182512b06beb0c41a30aa 448 SUPERFAMILY SSF55604 1 66 2.88E-13 T 10-11-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 A4G23_RS11730 41e70cec197182512b06beb0c41a30aa 448 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 6 23 - T 10-11-2016 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 A4G23_RS06705 032cb7d4cc2fde132d74dbe18eb483c5 897 Gene3D G3DSA:3.40.50.970 487 722 8.1E-109 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS06705 032cb7d4cc2fde132d74dbe18eb483c5 897 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 15 896 0.0 T 10-11-2016 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 A4G23_RS06705 032cb7d4cc2fde132d74dbe18eb483c5 897 Gene3D G3DSA:3.40.50.970 66 480 2.1E-133 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS06705 032cb7d4cc2fde132d74dbe18eb483c5 897 Gene3D G3DSA:3.40.50.920 728 897 6.0E-66 T 10-11-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 A4G23_RS06705 032cb7d4cc2fde132d74dbe18eb483c5 897 SUPERFAMILY SSF52518 487 719 1.77E-87 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS06705 032cb7d4cc2fde132d74dbe18eb483c5 897 SUPERFAMILY SSF52518 66 479 5.68E-111 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS06705 032cb7d4cc2fde132d74dbe18eb483c5 897 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 149 302 2.8E-9 T 10-11-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A4G23_RS06705 032cb7d4cc2fde132d74dbe18eb483c5 897 SUPERFAMILY SSF52922 726 897 6.12E-50 T 10-11-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 A4G23_RS06705 032cb7d4cc2fde132d74dbe18eb483c5 897 PIRSF PIRSF000156 5 897 0.0 T 10-11-2016 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 A4G23_RS11180 77346f0aea842e9e6aa27b8e031f5662 787 Pfam PF00122 E1-E2 ATPase 222 442 5.7E-54 T 10-11-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 A4G23_RS11180 77346f0aea842e9e6aa27b8e031f5662 787 Pfam PF00702 haloacid dehalogenase-like hydrolase 447 668 1.2E-34 T 10-11-2016 A4G23_RS11180 77346f0aea842e9e6aa27b8e031f5662 787 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 453 459 - T 10-11-2016 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 A4G23_RS11180 77346f0aea842e9e6aa27b8e031f5662 787 Gene3D G3DSA:3.40.50.1000 580 722 1.5E-46 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS11180 77346f0aea842e9e6aa27b8e031f5662 787 Gene3D G3DSA:3.40.50.1000 424 466 1.5E-46 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS11180 77346f0aea842e9e6aa27b8e031f5662 787 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 301 315 3.8E-21 T 10-11-2016 A4G23_RS11180 77346f0aea842e9e6aa27b8e031f5662 787 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 677 689 3.8E-21 T 10-11-2016 A4G23_RS11180 77346f0aea842e9e6aa27b8e031f5662 787 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 599 609 3.8E-21 T 10-11-2016 A4G23_RS11180 77346f0aea842e9e6aa27b8e031f5662 787 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 654 673 3.8E-21 T 10-11-2016 A4G23_RS11180 77346f0aea842e9e6aa27b8e031f5662 787 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 451 465 3.8E-21 T 10-11-2016 A4G23_RS11180 77346f0aea842e9e6aa27b8e031f5662 787 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 211 757 7.0E-141 T 10-11-2016 A4G23_RS11180 77346f0aea842e9e6aa27b8e031f5662 787 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 213 756 2.3E-105 T 10-11-2016 A4G23_RS11180 77346f0aea842e9e6aa27b8e031f5662 787 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 168 756 3.5E-163 T 10-11-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A4G23_RS11180 77346f0aea842e9e6aa27b8e031f5662 787 SUPERFAMILY SSF56784 449 469 1.31E-49 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS11180 77346f0aea842e9e6aa27b8e031f5662 787 SUPERFAMILY SSF56784 549 754 1.31E-49 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS11180 77346f0aea842e9e6aa27b8e031f5662 787 SUPERFAMILY SSF81665 352 445 1.29E-6 T 10-11-2016 A4G23_RS11180 77346f0aea842e9e6aa27b8e031f5662 787 SUPERFAMILY SSF81665 231 253 1.29E-6 T 10-11-2016 A4G23_RS11180 77346f0aea842e9e6aa27b8e031f5662 787 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 654 670 1.7E-6 T 10-11-2016 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A4G23_RS11180 77346f0aea842e9e6aa27b8e031f5662 787 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 685 710 1.7E-6 T 10-11-2016 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A4G23_RS11180 77346f0aea842e9e6aa27b8e031f5662 787 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 626 642 1.7E-6 T 10-11-2016 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A4G23_RS11180 77346f0aea842e9e6aa27b8e031f5662 787 SUPERFAMILY SSF55008 10 79 2.75E-17 T 10-11-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A4G23_RS11180 77346f0aea842e9e6aa27b8e031f5662 787 Gene3D G3DSA:3.30.70.100 13 92 2.2E-20 T 10-11-2016 A4G23_RS11180 77346f0aea842e9e6aa27b8e031f5662 787 Gene3D G3DSA:2.70.150.10 244 351 5.0E-19 T 10-11-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 A4G23_RS11180 77346f0aea842e9e6aa27b8e031f5662 787 Pfam PF00403 Heavy-metal-associated domain 17 73 1.8E-11 T 10-11-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A4G23_RS11180 77346f0aea842e9e6aa27b8e031f5662 787 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 225 476 6.9E-37 T 10-11-2016 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A4G23_RS11180 77346f0aea842e9e6aa27b8e031f5662 787 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 563 737 1.1E-36 T 10-11-2016 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A4G23_RS11180 77346f0aea842e9e6aa27b8e031f5662 787 ProSitePatterns PS01047 Heavy-metal-associated domain. 18 46 - T 10-11-2016 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 A4G23_RS11180 77346f0aea842e9e6aa27b8e031f5662 787 Gene3D G3DSA:3.40.1110.10 467 579 5.8E-12 T 10-11-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A4G23_RS11180 77346f0aea842e9e6aa27b8e031f5662 787 ProSitePatterns PS01229 Hypothetical cof family signature 2. 654 676 - T 10-11-2016 A4G23_RS11180 77346f0aea842e9e6aa27b8e031f5662 787 SUPERFAMILY SSF81653 257 351 4.05E-19 T 10-11-2016 A4G23_RS09490 74d1600e3a9a36bc059beb67cf38efc4 195 Pfam PF00857 Isochorismatase family 4 190 2.9E-33 T 10-11-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 A4G23_RS09490 74d1600e3a9a36bc059beb67cf38efc4 195 SUPERFAMILY SSF52499 2 190 7.06E-46 T 10-11-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 A4G23_RS09490 74d1600e3a9a36bc059beb67cf38efc4 195 Gene3D G3DSA:3.40.50.850 1 190 2.2E-57 T 10-11-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 A4G23_RS00610 f61dfc271576ca01a74e4c9227f0a358 821 Pfam PF01804 Penicillin amidase 61 808 2.0E-120 T 10-11-2016 IPR002692 Penicillin/cephalosporin acylase GO:0016787|GO:0017000 A4G23_RS00610 f61dfc271576ca01a74e4c9227f0a358 821 SUPERFAMILY SSF56235 60 817 4.37E-142 T 10-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal A4G23_RS00610 f61dfc271576ca01a74e4c9227f0a358 821 Gene3D G3DSA:2.30.120.10 350 408 5.2E-15 T 10-11-2016 A4G23_RS00610 f61dfc271576ca01a74e4c9227f0a358 821 Gene3D G3DSA:3.60.20.10 267 349 5.5E-65 T 10-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal A4G23_RS00610 f61dfc271576ca01a74e4c9227f0a358 821 Gene3D G3DSA:3.60.20.10 429 646 5.5E-65 T 10-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal A4G23_RS00610 f61dfc271576ca01a74e4c9227f0a358 821 Gene3D G3DSA:3.60.20.10 198 226 5.5E-65 T 10-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal A4G23_RS00610 f61dfc271576ca01a74e4c9227f0a358 821 Gene3D G3DSA:1.10.439.10 60 197 5.8E-32 T 10-11-2016 IPR023343 Penicillin amidase type, domain1 GO:0016811 A4G23_RS06170 afe48e475d7ee5fc059b4f8e95cf71b6 342 Gene3D G3DSA:2.30.30.60 195 243 6.8E-11 T 10-11-2016 A4G23_RS06170 afe48e475d7ee5fc059b4f8e95cf71b6 342 SUPERFAMILY SSF50182 179 244 6.87E-16 T 10-11-2016 IPR010920 LSM domain A4G23_RS06170 afe48e475d7ee5fc059b4f8e95cf71b6 342 Pfam PF00924 Mechanosensitive ion channel 137 330 1.2E-30 T 10-11-2016 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 A4G23_RS10940 d3c138682b7b55cdd8e326203056e5df 353 Gene3D G3DSA:3.60.70.12 8 345 4.1E-80 T 10-11-2016 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A4G23_RS10940 d3c138682b7b55cdd8e326203056e5df 353 SUPERFAMILY SSF56266 237 343 3.01E-62 T 10-11-2016 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A4G23_RS10940 d3c138682b7b55cdd8e326203056e5df 353 SUPERFAMILY SSF56266 8 208 3.01E-62 T 10-11-2016 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A4G23_RS10940 d3c138682b7b55cdd8e326203056e5df 353 Pfam PF03576 Peptidase family S58 9 344 2.1E-64 T 10-11-2016 IPR005321 Peptidase S58, DmpA A4G23_RS04210 2695f3da19a6b4cc806aa1c9ce5ffd66 310 SMART SM00475 6 280 1.7E-84 T 10-11-2016 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 A4G23_RS04210 2695f3da19a6b4cc806aa1c9ce5ffd66 310 Gene3D G3DSA:3.40.50.1010 5 185 3.4E-49 T 10-11-2016 IPR029060 PIN domain-like A4G23_RS04210 2695f3da19a6b4cc806aa1c9ce5ffd66 310 Gene3D G3DSA:1.10.150.20 186 259 6.0E-19 T 10-11-2016 A4G23_RS04210 2695f3da19a6b4cc806aa1c9ce5ffd66 310 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 191 272 3.0E-20 T 10-11-2016 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 A4G23_RS04210 2695f3da19a6b4cc806aa1c9ce5ffd66 310 SUPERFAMILY SSF88723 7 169 3.43E-39 T 10-11-2016 IPR029060 PIN domain-like A4G23_RS04210 2695f3da19a6b4cc806aa1c9ce5ffd66 310 SUPERFAMILY SSF47807 192 303 9.42E-22 T 10-11-2016 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 A4G23_RS04210 2695f3da19a6b4cc806aa1c9ce5ffd66 310 SMART SM00279 189 224 3.3E-11 T 10-11-2016 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 A4G23_RS04210 2695f3da19a6b4cc806aa1c9ce5ffd66 310 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 7 185 3.5E-48 T 10-11-2016 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 A4G23_RS19215 67653824f1ba5e1be729b4d0e37c01ac 1294 Pfam PF02779 Transketolase, pyrimidine binding domain 945 1138 8.8E-58 T 10-11-2016 IPR005475 Transketolase-like, pyrimidine-binding domain A4G23_RS19215 67653824f1ba5e1be729b4d0e37c01ac 1294 Gene3D G3DSA:3.30.559.10 169 407 1.0E-49 T 10-11-2016 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 A4G23_RS19215 67653824f1ba5e1be729b4d0e37c01ac 1294 Gene3D G3DSA:3.40.50.970 517 886 9.6E-78 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS19215 67653824f1ba5e1be729b4d0e37c01ac 1294 SUPERFAMILY SSF52518 475 882 9.16E-85 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS19215 67653824f1ba5e1be729b4d0e37c01ac 1294 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 438 1292 0.0 T 10-11-2016 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 A4G23_RS19215 67653824f1ba5e1be729b4d0e37c01ac 1294 SUPERFAMILY SSF52518 942 1146 4.12E-46 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS19215 67653824f1ba5e1be729b4d0e37c01ac 1294 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 24 61 7.9E-12 T 10-11-2016 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 A4G23_RS19215 67653824f1ba5e1be729b4d0e37c01ac 1294 SMART SM00861 946 1139 4.4E-52 T 10-11-2016 IPR005475 Transketolase-like, pyrimidine-binding domain A4G23_RS19215 67653824f1ba5e1be729b4d0e37c01ac 1294 Pfam PF00676 Dehydrogenase E1 component 560 881 4.4E-54 T 10-11-2016 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 A4G23_RS19215 67653824f1ba5e1be729b4d0e37c01ac 1294 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 1144 1292 1.3E-45 T 10-11-2016 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 A4G23_RS19215 67653824f1ba5e1be729b4d0e37c01ac 1294 Gene3D G3DSA:3.40.50.970 951 1150 6.4E-23 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS19215 67653824f1ba5e1be729b4d0e37c01ac 1294 SUPERFAMILY SSF52777 165 407 7.56E-54 T 10-11-2016 A4G23_RS19215 67653824f1ba5e1be729b4d0e37c01ac 1294 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 179 407 6.3E-49 T 10-11-2016 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A4G23_RS13175 1c4323ac7f211ff6fd6905851a8fbcfc 581 SUPERFAMILY SSF56112 35 302 1.12E-71 T 10-11-2016 IPR011009 Protein kinase-like domain A4G23_RS13175 1c4323ac7f211ff6fd6905851a8fbcfc 581 Pfam PF00069 Protein kinase domain 37 291 1.1E-45 T 10-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4G23_RS13175 1c4323ac7f211ff6fd6905851a8fbcfc 581 Gene3D G3DSA:3.30.200.20 32 120 1.6E-25 T 10-11-2016 A4G23_RS13175 1c4323ac7f211ff6fd6905851a8fbcfc 581 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 160 172 - T 10-11-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 A4G23_RS13175 1c4323ac7f211ff6fd6905851a8fbcfc 581 SMART SM00220 37 303 2.8E-57 T 10-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4G23_RS13175 1c4323ac7f211ff6fd6905851a8fbcfc 581 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 43 66 - T 10-11-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 A4G23_RS13175 1c4323ac7f211ff6fd6905851a8fbcfc 581 Gene3D G3DSA:1.10.510.10 423 456 2.8E-45 T 10-11-2016 A4G23_RS13175 1c4323ac7f211ff6fd6905851a8fbcfc 581 Gene3D G3DSA:1.10.510.10 127 301 2.8E-45 T 10-11-2016 A4G23_RS03700 4fb3d5f926bc212c8d384a51cfa9bd5f 181 Pfam PF00156 Phosphoribosyl transferase domain 57 156 7.3E-16 T 10-11-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 A4G23_RS03700 4fb3d5f926bc212c8d384a51cfa9bd5f 181 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 10 181 34.82 T 10-11-2016 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|Reactome: R-HSA-74217 A4G23_RS03700 4fb3d5f926bc212c8d384a51cfa9bd5f 181 SUPERFAMILY SSF53271 12 169 6.29E-48 T 10-11-2016 IPR029057 Phosphoribosyltransferase-like A4G23_RS03700 4fb3d5f926bc212c8d384a51cfa9bd5f 181 Gene3D G3DSA:3.40.50.2020 8 177 2.2E-61 T 10-11-2016 IPR029057 Phosphoribosyltransferase-like A4G23_RS03700 4fb3d5f926bc212c8d384a51cfa9bd5f 181 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 11 169 5.2E-58 T 10-11-2016 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|Reactome: R-HSA-74217 A4G23_RS05925 1febd589eb9ea9368cc6c76a938b856f 107 TIGRFAM TIGR01795 CM_mono_cladeE: chorismate mutase 20 107 5.3E-46 T 10-11-2016 IPR010951 Chorismate mutase, bacteria A4G23_RS05925 1febd589eb9ea9368cc6c76a938b856f 107 Gene3D G3DSA:1.20.59.10 17 105 4.2E-21 T 10-11-2016 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A4G23_RS05925 1febd589eb9ea9368cc6c76a938b856f 107 SUPERFAMILY SSF48600 18 106 1.19E-24 T 10-11-2016 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A4G23_RS05925 1febd589eb9ea9368cc6c76a938b856f 107 Pfam PF01817 Chorismate mutase type II 27 102 2.7E-17 T 10-11-2016 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A4G23_RS05925 1febd589eb9ea9368cc6c76a938b856f 107 SMART SM00830 27 107 1.0E-22 T 10-11-2016 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A4G23_RS26460 086fb6f164bc93ab4732409803512a7a 151 TIGRFAM TIGR02241 TIGR02241: conserved hypothetical phage tail region protein 8 149 9.2E-36 T 10-11-2016 IPR011747 Conserved hypothetical protein CHP02241 A4G23_RS26460 086fb6f164bc93ab4732409803512a7a 151 Pfam PF06841 T4-like virus tail tube protein gp19 12 148 2.4E-39 T 10-11-2016 IPR010667 Bacteriophage T4, Gp19, tail tube GO:0005198 A4G23_RS22050 8110812fe829fd6a18a4f5a81364c2b2 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 13 28 3.0E-9 T 10-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4G23_RS22050 8110812fe829fd6a18a4f5a81364c2b2 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 3.0E-9 T 10-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4G23_RS22050 8110812fe829fd6a18a4f5a81364c2b2 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 3.0E-9 T 10-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4G23_RS22050 8110812fe829fd6a18a4f5a81364c2b2 113 SUPERFAMILY SSF46785 5 88 3.32E-21 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS22050 8110812fe829fd6a18a4f5a81364c2b2 113 Gene3D G3DSA:1.10.10.10 10 107 2.8E-24 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS22050 8110812fe829fd6a18a4f5a81364c2b2 113 SMART SM00418 11 89 1.9E-21 T 10-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4G23_RS22050 8110812fe829fd6a18a4f5a81364c2b2 113 Pfam PF01022 Bacterial regulatory protein, arsR family 18 64 2.1E-12 T 10-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4G23_RS16600 d35654293dc2e94d70aeab4558b9f5eb 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 27.897 T 10-11-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS16600 d35654293dc2e94d70aeab4558b9f5eb 102 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 4.6E-21 T 10-11-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS16600 d35654293dc2e94d70aeab4558b9f5eb 102 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 4.6E-21 T 10-11-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS16600 d35654293dc2e94d70aeab4558b9f5eb 102 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 4.6E-21 T 10-11-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS16600 d35654293dc2e94d70aeab4558b9f5eb 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 10-11-2016 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS16600 d35654293dc2e94d70aeab4558b9f5eb 102 SUPERFAMILY SSF54999 5 102 1.02E-38 T 10-11-2016 IPR027486 Ribosomal protein S10 domain A4G23_RS16600 d35654293dc2e94d70aeab4558b9f5eb 102 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 7.9E-37 T 10-11-2016 IPR027486 Ribosomal protein S10 domain A4G23_RS16600 d35654293dc2e94d70aeab4558b9f5eb 102 SMART SM01403 7 101 3.5E-59 T 10-11-2016 IPR027486 Ribosomal protein S10 domain A4G23_RS16600 d35654293dc2e94d70aeab4558b9f5eb 102 Gene3D G3DSA:3.30.70.600 4 102 5.6E-45 T 10-11-2016 IPR027486 Ribosomal protein S10 domain A4G23_RS16600 d35654293dc2e94d70aeab4558b9f5eb 102 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 1.1E-47 T 10-11-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS02205 ce8d1def568348adc0d7313a0f5479dc 568 SUPERFAMILY SSF53067 19 295 8.29E-37 T 10-11-2016 A4G23_RS02205 ce8d1def568348adc0d7313a0f5479dc 568 Gene3D G3DSA:3.30.420.40 294 543 1.8E-54 T 10-11-2016 A4G23_RS02205 ce8d1def568348adc0d7313a0f5479dc 568 Gene3D G3DSA:3.30.420.40 18 290 9.2E-39 T 10-11-2016 A4G23_RS02205 ce8d1def568348adc0d7313a0f5479dc 568 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 303 499 4.7E-43 T 10-11-2016 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 A4G23_RS02205 ce8d1def568348adc0d7313a0f5479dc 568 Hamap MF_00520 Ribulokinase [araB]. 16 556 46.008 T 10-11-2016 IPR005929 Ribulokinase GO:0005524|GO:0008741|GO:0019569 KEGG: 00040+2.7.1.16 A4G23_RS02205 ce8d1def568348adc0d7313a0f5479dc 568 SUPERFAMILY SSF53067 294 545 7.77E-58 T 10-11-2016 A4G23_RS02205 ce8d1def568348adc0d7313a0f5479dc 568 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 411 431 - T 10-11-2016 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A4G23_RS02205 ce8d1def568348adc0d7313a0f5479dc 568 PIRSF PIRSF000538 16 544 1.3E-58 T 10-11-2016 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A4G23_RS02205 ce8d1def568348adc0d7313a0f5479dc 568 TIGRFAM TIGR01234 L-ribulokinase: ribulokinase 18 546 3.4E-227 T 10-11-2016 IPR005929 Ribulokinase GO:0005524|GO:0008741|GO:0019569 KEGG: 00040+2.7.1.16 A4G23_RS02205 ce8d1def568348adc0d7313a0f5479dc 568 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 19 218 4.4E-6 T 10-11-2016 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 A4G23_RS03975 7cdadbffa59b2dfb9783ef4e54061d45 476 Gene3D G3DSA:1.10.40.30 383 439 1.8E-27 T 10-11-2016 A4G23_RS03975 7cdadbffa59b2dfb9783ef4e54061d45 476 SUPERFAMILY SSF48557 13 462 7.07E-137 T 10-11-2016 IPR008948 L-Aspartase-like GO:0003824 A4G23_RS03975 7cdadbffa59b2dfb9783ef4e54061d45 476 ProSitePatterns PS00163 Fumarate lyases signature. 284 293 - T 10-11-2016 IPR020557 Fumarate lyase, conserved site GO:0003824 A4G23_RS03975 7cdadbffa59b2dfb9783ef4e54061d45 476 Hamap MF_00006 Argininosuccinate lyase [argH]. 9 462 40.984 T 10-11-2016 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4G23_RS03975 7cdadbffa59b2dfb9783ef4e54061d45 476 PRINTS PR00149 Fumarate lyase superfamily signature 155 173 3.8E-26 T 10-11-2016 IPR000362 Fumarate lyase family A4G23_RS03975 7cdadbffa59b2dfb9783ef4e54061d45 476 PRINTS PR00149 Fumarate lyase superfamily signature 240 267 3.8E-26 T 10-11-2016 IPR000362 Fumarate lyase family A4G23_RS03975 7cdadbffa59b2dfb9783ef4e54061d45 476 PRINTS PR00149 Fumarate lyase superfamily signature 284 300 3.8E-26 T 10-11-2016 IPR000362 Fumarate lyase family A4G23_RS03975 7cdadbffa59b2dfb9783ef4e54061d45 476 PRINTS PR00149 Fumarate lyase superfamily signature 110 128 3.8E-26 T 10-11-2016 IPR000362 Fumarate lyase family A4G23_RS03975 7cdadbffa59b2dfb9783ef4e54061d45 476 Pfam PF14698 Argininosuccinate lyase C-terminal 372 437 1.3E-21 T 10-11-2016 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4G23_RS03975 7cdadbffa59b2dfb9783ef4e54061d45 476 PRINTS PR00145 Argininosuccinate lyase family signature 201 217 2.4E-54 T 10-11-2016 A4G23_RS03975 7cdadbffa59b2dfb9783ef4e54061d45 476 PRINTS PR00145 Argininosuccinate lyase family signature 319 338 2.4E-54 T 10-11-2016 A4G23_RS03975 7cdadbffa59b2dfb9783ef4e54061d45 476 PRINTS PR00145 Argininosuccinate lyase family signature 109 131 2.4E-54 T 10-11-2016 A4G23_RS03975 7cdadbffa59b2dfb9783ef4e54061d45 476 PRINTS PR00145 Argininosuccinate lyase family signature 240 264 2.4E-54 T 10-11-2016 A4G23_RS03975 7cdadbffa59b2dfb9783ef4e54061d45 476 PRINTS PR00145 Argininosuccinate lyase family signature 150 170 2.4E-54 T 10-11-2016 A4G23_RS03975 7cdadbffa59b2dfb9783ef4e54061d45 476 PRINTS PR00145 Argininosuccinate lyase family signature 284 300 2.4E-54 T 10-11-2016 A4G23_RS03975 7cdadbffa59b2dfb9783ef4e54061d45 476 TIGRFAM TIGR00838 argH: argininosuccinate lyase 10 464 1.2E-181 T 10-11-2016 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4G23_RS03975 7cdadbffa59b2dfb9783ef4e54061d45 476 Gene3D G3DSA:1.20.200.10 115 382 1.6E-98 T 10-11-2016 A4G23_RS03975 7cdadbffa59b2dfb9783ef4e54061d45 476 Gene3D G3DSA:1.10.275.10 9 114 5.3E-35 T 10-11-2016 IPR024083 Fumarase/histidase, N-terminal A4G23_RS03975 7cdadbffa59b2dfb9783ef4e54061d45 476 Pfam PF00206 Lyase 23 309 1.3E-65 T 10-11-2016 IPR022761 Fumarate lyase, N-terminal A4G23_RS02215 9e90c1ad6ce594db9a7d2e3c26888fc3 368 SUPERFAMILY SSF53822 38 355 2.19E-67 T 10-11-2016 IPR028082 Periplasmic binding protein-like I A4G23_RS02215 9e90c1ad6ce594db9a7d2e3c26888fc3 368 Gene3D G3DSA:3.40.50.2300 156 355 4.0E-34 T 10-11-2016 A4G23_RS02215 9e90c1ad6ce594db9a7d2e3c26888fc3 368 Pfam PF13407 Periplasmic binding protein domain 42 320 2.5E-65 T 10-11-2016 IPR025997 Periplasmic binding protein A4G23_RS02215 9e90c1ad6ce594db9a7d2e3c26888fc3 368 Gene3D G3DSA:3.40.50.2300 39 155 6.1E-33 T 10-11-2016 A4G23_RS16950 cadfe11f8b2a08f89e0e84a69fc96b6e 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 6.3E-23 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS16950 cadfe11f8b2a08f89e0e84a69fc96b6e 297 SUPERFAMILY SSF53850 91 296 4.83E-38 T 10-11-2016 A4G23_RS16950 cadfe11f8b2a08f89e0e84a69fc96b6e 297 Gene3D G3DSA:3.40.190.10 180 266 1.5E-29 T 10-11-2016 A4G23_RS16950 cadfe11f8b2a08f89e0e84a69fc96b6e 297 Gene3D G3DSA:3.40.190.10 91 179 3.2E-19 T 10-11-2016 A4G23_RS16950 cadfe11f8b2a08f89e0e84a69fc96b6e 297 SUPERFAMILY SSF46785 3 112 1.3E-24 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS16950 cadfe11f8b2a08f89e0e84a69fc96b6e 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 9.3E-8 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS16950 cadfe11f8b2a08f89e0e84a69fc96b6e 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 9.3E-8 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS16950 cadfe11f8b2a08f89e0e84a69fc96b6e 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 9.3E-8 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS16950 cadfe11f8b2a08f89e0e84a69fc96b6e 297 Gene3D G3DSA:1.10.10.10 3 88 1.9E-28 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS16950 cadfe11f8b2a08f89e0e84a69fc96b6e 297 Pfam PF03466 LysR substrate binding domain 89 293 6.8E-45 T 10-11-2016 IPR005119 LysR, substrate-binding A4G23_RS04160 67c5ef23d31c4f264072224cb27ae4dd 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 4 238 1.3E-70 T 10-11-2016 A4G23_RS04160 67c5ef23d31c4f264072224cb27ae4dd 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 201 221 1.9E-37 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS04160 67c5ef23d31c4f264072224cb27ae4dd 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 1.9E-37 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS04160 67c5ef23d31c4f264072224cb27ae4dd 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 163 1.9E-37 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS04160 67c5ef23d31c4f264072224cb27ae4dd 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 117 133 1.9E-37 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS04160 67c5ef23d31c4f264072224cb27ae4dd 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 68 79 1.9E-37 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS04160 67c5ef23d31c4f264072224cb27ae4dd 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 1 14 1.9E-37 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS04160 67c5ef23d31c4f264072224cb27ae4dd 245 Gene3D G3DSA:3.40.50.720 1 238 2.7E-83 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS04160 67c5ef23d31c4f264072224cb27ae4dd 245 SUPERFAMILY SSF51735 1 237 8.05E-78 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS04160 67c5ef23d31c4f264072224cb27ae4dd 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 123 131 9.0E-10 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS04160 67c5ef23d31c4f264072224cb27ae4dd 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 163 9.0E-10 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS04160 67c5ef23d31c4f264072224cb27ae4dd 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 68 79 9.0E-10 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS22375 8664a8d995ede20c316f63d634f1b418 251 PRINTS PR00164 ABC-2 type transport system membrane protein signature 135 159 2.3E-6 T 10-11-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 A4G23_RS22375 8664a8d995ede20c316f63d634f1b418 251 PRINTS PR00164 ABC-2 type transport system membrane protein signature 192 211 2.3E-6 T 10-11-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 A4G23_RS22375 8664a8d995ede20c316f63d634f1b418 251 PRINTS PR00164 ABC-2 type transport system membrane protein signature 172 191 2.3E-6 T 10-11-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 A4G23_RS22375 8664a8d995ede20c316f63d634f1b418 251 Pfam PF01061 ABC-2 type transporter 5 214 8.4E-28 T 10-11-2016 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A4G23_RS22375 8664a8d995ede20c316f63d634f1b418 251 PIRSF PIRSF006648 2 249 4.7E-30 T 10-11-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 A4G23_RS25125 e098bfa1bd105ff05a8da74c37ddaf7e 292 Pfam PF00106 short chain dehydrogenase 12 196 3.2E-40 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS25125 e098bfa1bd105ff05a8da74c37ddaf7e 292 SUPERFAMILY SSF51735 7 265 6.29E-54 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS25125 e098bfa1bd105ff05a8da74c37ddaf7e 292 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 11 196 1.1E-4 T 10-11-2016 A4G23_RS25125 e098bfa1bd105ff05a8da74c37ddaf7e 292 Gene3D G3DSA:3.40.50.720 10 238 1.4E-50 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS25125 e098bfa1bd105ff05a8da74c37ddaf7e 292 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 10-11-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4G23_RS25125 e098bfa1bd105ff05a8da74c37ddaf7e 292 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 5.5E-6 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS25125 e098bfa1bd105ff05a8da74c37ddaf7e 292 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 5.5E-6 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS25125 e098bfa1bd105ff05a8da74c37ddaf7e 292 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 5.5E-6 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS25125 e098bfa1bd105ff05a8da74c37ddaf7e 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 3.0E-15 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS25125 e098bfa1bd105ff05a8da74c37ddaf7e 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 3.0E-15 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS25125 e098bfa1bd105ff05a8da74c37ddaf7e 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 3.0E-15 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS25125 e098bfa1bd105ff05a8da74c37ddaf7e 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 3.0E-15 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS04150 31eb59d057ae4fb6104208d67053a230 400 Gene3D G3DSA:3.20.20.10 116 275 2.9E-9 T 10-11-2016 IPR029066 PLP-binding barrel A4G23_RS04150 31eb59d057ae4fb6104208d67053a230 400 SUPERFAMILY SSF51419 26 272 2.29E-23 T 10-11-2016 IPR029066 PLP-binding barrel A4G23_RS04150 31eb59d057ae4fb6104208d67053a230 400 Pfam PF01168 Alanine racemase, N-terminal domain 25 273 9.2E-19 T 10-11-2016 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4G23_RS21655 18a3c35f934d8214c01b4dc5b073254c 1089 Gene3D G3DSA:2.30.38.10 374 445 5.2E-18 T 10-11-2016 A4G23_RS21655 18a3c35f934d8214c01b4dc5b073254c 1089 ProSitePatterns PS00455 Putative AMP-binding domain signature. 201 212 - T 10-11-2016 IPR020845 AMP-binding, conserved site A4G23_RS21655 18a3c35f934d8214c01b4dc5b073254c 1089 SUPERFAMILY SSF47336 565 634 4.32E-16 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS21655 18a3c35f934d8214c01b4dc5b073254c 1089 SUPERFAMILY SSF56801 27 585 2.35E-119 T 10-11-2016 A4G23_RS21655 18a3c35f934d8214c01b4dc5b073254c 1089 Gene3D G3DSA:3.40.50.980 223 373 9.1E-35 T 10-11-2016 A4G23_RS21655 18a3c35f934d8214c01b4dc5b073254c 1089 Gene3D G3DSA:3.40.50.980 186 222 7.1E-34 T 10-11-2016 A4G23_RS21655 18a3c35f934d8214c01b4dc5b073254c 1089 Gene3D G3DSA:3.40.50.980 44 154 7.1E-34 T 10-11-2016 A4G23_RS21655 18a3c35f934d8214c01b4dc5b073254c 1089 Pfam PF13193 AMP-binding enzyme C-terminal domain 473 543 5.6E-8 T 10-11-2016 IPR025110 AMP-binding enzyme C-terminal domain A4G23_RS21655 18a3c35f934d8214c01b4dc5b073254c 1089 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 68 489 4.3E-105 T 10-11-2016 IPR010071 Amino acid adenylation domain A4G23_RS21655 18a3c35f934d8214c01b4dc5b073254c 1089 Gene3D G3DSA:1.10.1200.10 576 637 3.8E-22 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS21655 18a3c35f934d8214c01b4dc5b073254c 1089 Pfam PF00501 AMP-binding enzyme 49 465 7.2E-75 T 10-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A4G23_RS21655 18a3c35f934d8214c01b4dc5b073254c 1089 Pfam PF00550 Phosphopantetheine attachment site 574 634 1.7E-10 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS21655 18a3c35f934d8214c01b4dc5b073254c 1089 Gene3D G3DSA:3.30.300.30 461 575 7.3E-29 T 10-11-2016 A4G23_RS21655 18a3c35f934d8214c01b4dc5b073254c 1089 SUPERFAMILY SSF52777 696 837 7.41E-16 T 10-11-2016 A4G23_RS21655 18a3c35f934d8214c01b4dc5b073254c 1089 Pfam PF00668 Condensation domain 701 818 1.8E-9 T 10-11-2016 IPR001242 Condensation domain A4G23_RS24845 fc8c27b219d17f10fcbef76c6cf6ac05 179 SUPERFAMILY SSF55729 17 142 4.01E-23 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS24845 fc8c27b219d17f10fcbef76c6cf6ac05 179 Gene3D G3DSA:3.40.630.30 15 160 9.4E-18 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS24845 fc8c27b219d17f10fcbef76c6cf6ac05 179 Pfam PF00583 Acetyltransferase (GNAT) family 66 136 5.0E-8 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS16635 6301877f3daa1f163ea7a966296ededf 275 Pfam PF00189 Ribosomal protein S3, C-terminal domain 119 201 1.2E-36 T 10-11-2016 A4G23_RS16635 6301877f3daa1f163ea7a966296ededf 275 SMART SM00322 59 124 1.2E-6 T 10-11-2016 IPR004087 K Homology domain GO:0003676 A4G23_RS16635 6301877f3daa1f163ea7a966296ededf 275 Gene3D G3DSA:3.30.1140.32 107 206 4.2E-42 T 10-11-2016 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS16635 6301877f3daa1f163ea7a966296ededf 275 Gene3D G3DSA:3.30.300.20 17 106 6.1E-31 T 10-11-2016 IPR015946 K homology domain-like, alpha/beta A4G23_RS16635 6301877f3daa1f163ea7a966296ededf 275 SUPERFAMILY SSF54821 106 205 1.7E-37 T 10-11-2016 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS16635 6301877f3daa1f163ea7a966296ededf 275 SUPERFAMILY SSF54814 2 105 3.92E-34 T 10-11-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 A4G23_RS16635 6301877f3daa1f163ea7a966296ededf 275 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 207 6.7E-92 T 10-11-2016 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 A4G23_RS16635 6301877f3daa1f163ea7a966296ededf 275 Pfam PF07650 KH domain 38 109 1.5E-18 T 10-11-2016 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS16635 6301877f3daa1f163ea7a966296ededf 275 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 205 37.548 T 10-11-2016 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 A4G23_RS16635 6301877f3daa1f163ea7a966296ededf 275 ProSitePatterns PS00548 Ribosomal protein S3 signature. 162 196 - T 10-11-2016 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS22690 20e81d0476ed816ff238b03527c267b7 427 Pfam PF12146 Serine aminopeptidase, S33 145 392 3.9E-9 T 10-11-2016 IPR022742 Serine aminopeptidase, S33 A4G23_RS22690 20e81d0476ed816ff238b03527c267b7 427 SUPERFAMILY SSF53474 270 414 3.1E-26 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS22690 20e81d0476ed816ff238b03527c267b7 427 SUPERFAMILY SSF53474 76 241 3.1E-26 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS22690 20e81d0476ed816ff238b03527c267b7 427 Gene3D G3DSA:3.40.50.1820 334 403 1.8E-23 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS22690 20e81d0476ed816ff238b03527c267b7 427 Gene3D G3DSA:3.40.50.1820 80 241 1.8E-23 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS22690 20e81d0476ed816ff238b03527c267b7 427 PIRSF PIRSF029171 4 420 1.9E-80 T 10-11-2016 IPR005152 Lipase, secreted GO:0004806|GO:0016042 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 A4G23_RS00535 520a69b20cc10ef11dcfc19d194dca8e 814 SUPERFAMILY SSF55874 717 796 4.95E-6 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS00535 520a69b20cc10ef11dcfc19d194dca8e 814 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 479 673 3.7E-49 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS00535 520a69b20cc10ef11dcfc19d194dca8e 814 SMART SM00091 131 197 0.21 T 10-11-2016 IPR000014 PAS domain A4G23_RS00535 520a69b20cc10ef11dcfc19d194dca8e 814 SMART SM00091 10 77 0.0084 T 10-11-2016 IPR000014 PAS domain A4G23_RS00535 520a69b20cc10ef11dcfc19d194dca8e 814 SMART SM00331 449 673 1.7E-40 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS00535 520a69b20cc10ef11dcfc19d194dca8e 814 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 21 105 5.6E-6 T 10-11-2016 IPR000014 PAS domain A4G23_RS00535 520a69b20cc10ef11dcfc19d194dca8e 814 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 135 256 6.5E-10 T 10-11-2016 IPR000014 PAS domain A4G23_RS00535 520a69b20cc10ef11dcfc19d194dca8e 814 SUPERFAMILY SSF55785 130 247 6.28E-13 T 10-11-2016 IPR000014 PAS domain A4G23_RS00535 520a69b20cc10ef11dcfc19d194dca8e 814 SUPERFAMILY SSF55785 22 110 1.65E-11 T 10-11-2016 IPR000014 PAS domain A4G23_RS00535 520a69b20cc10ef11dcfc19d194dca8e 814 Pfam PF08448 PAS fold 139 251 7.8E-19 T 10-11-2016 IPR013656 PAS fold-4 A4G23_RS00535 520a69b20cc10ef11dcfc19d194dca8e 814 SUPERFAMILY SSF55781 334 432 2.84E-14 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS00535 520a69b20cc10ef11dcfc19d194dca8e 814 Pfam PF13185 GAF domain 327 422 5.2E-9 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS00535 520a69b20cc10ef11dcfc19d194dca8e 814 SUPERFAMILY SSF81606 462 672 7.85E-8 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS00535 520a69b20cc10ef11dcfc19d194dca8e 814 Gene3D G3DSA:3.30.450.20 21 110 6.1E-10 T 10-11-2016 A4G23_RS00535 520a69b20cc10ef11dcfc19d194dca8e 814 Pfam PF00989 PAS fold 22 115 1.5E-5 T 10-11-2016 IPR013767 PAS fold GO:0006355 A4G23_RS00535 520a69b20cc10ef11dcfc19d194dca8e 814 Gene3D G3DSA:3.30.450.20 127 249 1.4E-15 T 10-11-2016 A4G23_RS00535 520a69b20cc10ef11dcfc19d194dca8e 814 SMART SM00065 271 431 6.5E-5 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS00535 520a69b20cc10ef11dcfc19d194dca8e 814 Pfam PF13581 Histidine kinase-like ATPase domain 687 794 2.4E-7 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS00535 520a69b20cc10ef11dcfc19d194dca8e 814 Gene3D G3DSA:3.30.450.40 259 429 1.9E-35 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS02435 284d08106f8b4180c9f6727191b0824f 254 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS02435 284d08106f8b4180c9f6727191b0824f 254 SUPERFAMILY SSF52540 1 221 1.64E-64 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS02435 284d08106f8b4180c9f6727191b0824f 254 Pfam PF00005 ABC transporter 22 169 9.1E-33 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS02435 284d08106f8b4180c9f6727191b0824f 254 Gene3D G3DSA:3.40.50.300 2 221 6.3E-67 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS02435 284d08106f8b4180c9f6727191b0824f 254 SMART SM00382 30 217 3.7E-17 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS22970 7d7f06a2dfecdbb5dcd464cfd139e6b3 460 SUPERFAMILY SSF51905 1 304 1.08E-52 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS22970 7d7f06a2dfecdbb5dcd464cfd139e6b3 460 SUPERFAMILY SSF51905 415 447 1.08E-52 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS22970 7d7f06a2dfecdbb5dcd464cfd139e6b3 460 Pfam PF01593 Flavin containing amine oxidoreductase 5 447 6.5E-45 T 10-11-2016 IPR002937 Amine oxidase GO:0016491|GO:0055114 A4G23_RS22970 7d7f06a2dfecdbb5dcd464cfd139e6b3 460 Gene3D G3DSA:3.90.660.20 226 398 6.5E-37 T 10-11-2016 IPR027418 Protoporphyrinogen oxidase, C-terminal domain KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 A4G23_RS22970 7d7f06a2dfecdbb5dcd464cfd139e6b3 460 Gene3D G3DSA:1.10.3110.10 98 187 6.0E-19 T 10-11-2016 A4G23_RS22970 7d7f06a2dfecdbb5dcd464cfd139e6b3 460 SUPERFAMILY SSF54373 288 398 5.3E-28 T 10-11-2016 A4G23_RS22970 7d7f06a2dfecdbb5dcd464cfd139e6b3 460 TIGRFAM TIGR00562 proto_IX_ox: protoporphyrinogen oxidase 1 447 1.6E-57 T 10-11-2016 IPR004572 Protoporphyrinogen oxidase GO:0004729|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 A4G23_RS22970 7d7f06a2dfecdbb5dcd464cfd139e6b3 460 Gene3D G3DSA:3.40.50.720 1 37 2.5E-7 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS05615 a3c4a75cc43e4d937ba3ee4d0b09bd8d 695 TIGRFAM TIGR00232 tktlase_bact: transketolase 19 688 1.2E-240 T 10-11-2016 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 A4G23_RS05615 a3c4a75cc43e4d937ba3ee4d0b09bd8d 695 SUPERFAMILY SSF52518 5 341 4.67E-106 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS05615 a3c4a75cc43e4d937ba3ee4d0b09bd8d 695 SMART SM00861 371 555 9.7E-63 T 10-11-2016 IPR005475 Transketolase-like, pyrimidine-binding domain A4G23_RS05615 a3c4a75cc43e4d937ba3ee4d0b09bd8d 695 Gene3D G3DSA:3.40.50.970 351 561 1.2E-72 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS05615 a3c4a75cc43e4d937ba3ee4d0b09bd8d 695 Pfam PF02779 Transketolase, pyrimidine binding domain 370 533 2.1E-43 T 10-11-2016 IPR005475 Transketolase-like, pyrimidine-binding domain A4G23_RS05615 a3c4a75cc43e4d937ba3ee4d0b09bd8d 695 ProSitePatterns PS00801 Transketolase signature 1. 24 44 - T 10-11-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A4G23_RS05615 a3c4a75cc43e4d937ba3ee4d0b09bd8d 695 Gene3D G3DSA:3.40.50.920 564 690 2.5E-48 T 10-11-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 A4G23_RS05615 a3c4a75cc43e4d937ba3ee4d0b09bd8d 695 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 16 355 1.3E-140 T 10-11-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A4G23_RS05615 a3c4a75cc43e4d937ba3ee4d0b09bd8d 695 ProSitePatterns PS00802 Transketolase signature 2. 491 507 - T 10-11-2016 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A4G23_RS05615 a3c4a75cc43e4d937ba3ee4d0b09bd8d 695 SUPERFAMILY SSF52922 560 691 1.83E-41 T 10-11-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 A4G23_RS05615 a3c4a75cc43e4d937ba3ee4d0b09bd8d 695 Pfam PF02780 Transketolase, C-terminal domain 570 682 4.4E-11 T 10-11-2016 IPR033248 Transketolase, C-terminal domain A4G23_RS05615 a3c4a75cc43e4d937ba3ee4d0b09bd8d 695 SUPERFAMILY SSF52518 358 556 2.47E-63 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS05615 a3c4a75cc43e4d937ba3ee4d0b09bd8d 695 Gene3D G3DSA:3.40.50.970 13 341 5.5E-114 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS01010 b99bc929321f6395cfc444b3d9a34d0b 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 7.8E-42 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS01010 b99bc929321f6395cfc444b3d9a34d0b 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 7.8E-42 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS01010 b99bc929321f6395cfc444b3d9a34d0b 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 7.8E-42 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS01010 b99bc929321f6395cfc444b3d9a34d0b 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 7.8E-42 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS01010 b99bc929321f6395cfc444b3d9a34d0b 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 7.8E-42 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS01010 b99bc929321f6395cfc444b3d9a34d0b 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 7.8E-42 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS01010 b99bc929321f6395cfc444b3d9a34d0b 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 4.9E-12 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS01010 b99bc929321f6395cfc444b3d9a34d0b 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 4.9E-12 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS01010 b99bc929321f6395cfc444b3d9a34d0b 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 4.9E-12 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS01010 b99bc929321f6395cfc444b3d9a34d0b 265 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 10-11-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4G23_RS01010 b99bc929321f6395cfc444b3d9a34d0b 265 Gene3D G3DSA:3.40.50.720 6 249 1.3E-81 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS01010 b99bc929321f6395cfc444b3d9a34d0b 265 SUPERFAMILY SSF51735 7 249 7.45E-80 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS01010 b99bc929321f6395cfc444b3d9a34d0b 265 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 246 1.8E-59 T 10-11-2016 A4G23_RS17315 f9679036b313f490e287e7f56580bbc2 441 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 28 438 47.984 T 10-11-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A4G23_RS17315 f9679036b313f490e287e7f56580bbc2 441 Gene3D G3DSA:3.40.640.10 58 303 4.9E-93 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS17315 f9679036b313f490e287e7f56580bbc2 441 Pfam PF00464 Serine hydroxymethyltransferase 30 405 4.5E-150 T 10-11-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A4G23_RS17315 f9679036b313f490e287e7f56580bbc2 441 SUPERFAMILY SSF53383 28 438 3.09E-159 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS17315 f9679036b313f490e287e7f56580bbc2 441 Gene3D G3DSA:3.90.1150.10 304 438 2.7E-49 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS17315 f9679036b313f490e287e7f56580bbc2 441 PIRSF PIRSF000412 9 440 4.7E-160 T 10-11-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A4G23_RS17315 f9679036b313f490e287e7f56580bbc2 441 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 243 259 - T 10-11-2016 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0004372|GO:0006544|GO:0006563|GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A4G23_RS22480 0b6388b508d4293bfd82d550d578331e 335 Pfam PF00107 Zinc-binding dehydrogenase 161 275 2.7E-16 T 10-11-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A4G23_RS22480 0b6388b508d4293bfd82d550d578331e 335 SMART SM00829 11 332 7.0E-7 T 10-11-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A4G23_RS22480 0b6388b508d4293bfd82d550d578331e 335 SUPERFAMILY SSF51735 123 286 1.06E-28 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS22480 0b6388b508d4293bfd82d550d578331e 335 SUPERFAMILY SSF50129 1 153 3.04E-27 T 10-11-2016 IPR011032 GroES-like A4G23_RS22480 0b6388b508d4293bfd82d550d578331e 335 Gene3D G3DSA:3.90.180.10 1 151 1.8E-31 T 10-11-2016 IPR011032 GroES-like A4G23_RS22480 0b6388b508d4293bfd82d550d578331e 335 Gene3D G3DSA:3.40.50.720 152 271 3.1E-18 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS01000 669a29f49d137162630c5c5542445deb 262 SUPERFAMILY SSF56300 2 227 6.03E-31 T 10-11-2016 IPR029052 Metallo-dependent phosphatase-like A4G23_RS01000 669a29f49d137162630c5c5542445deb 262 Pfam PF00149 Calcineurin-like phosphoesterase 2 208 1.9E-11 T 10-11-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 A4G23_RS01000 669a29f49d137162630c5c5542445deb 262 PIRSF PIRSF008292 1 238 8.5E-92 T 10-11-2016 IPR016538 Uncharacterised conserved protein UCP008292 A4G23_RS01000 669a29f49d137162630c5c5542445deb 262 Gene3D G3DSA:3.60.21.10 2 223 2.1E-23 T 10-11-2016 IPR029052 Metallo-dependent phosphatase-like A4G23_RS19460 81f2471b9d4b6a83b960f2f978a09e3e 149 Gene3D G3DSA:3.40.50.2300 7 123 1.5E-37 T 10-11-2016 A4G23_RS19460 81f2471b9d4b6a83b960f2f978a09e3e 149 SUPERFAMILY SSF52172 7 122 5.83E-36 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS19460 81f2471b9d4b6a83b960f2f978a09e3e 149 SMART SM00448 6 118 5.5E-33 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS19460 81f2471b9d4b6a83b960f2f978a09e3e 149 Pfam PF00072 Response regulator receiver domain 8 119 1.5E-27 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS13830 93aa9d227f833eb3092c910e369a7620 487 Gene3D G3DSA:3.90.230.10 223 482 9.0E-72 T 10-11-2016 IPR000994 Peptidase M24, structural domain A4G23_RS13830 93aa9d227f833eb3092c910e369a7620 487 SMART SM01011 51 193 8.7E-40 T 10-11-2016 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 A4G23_RS13830 93aa9d227f833eb3092c910e369a7620 487 Pfam PF05195 Aminopeptidase P, N-terminal domain 58 178 3.6E-19 T 10-11-2016 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 A4G23_RS13830 93aa9d227f833eb3092c910e369a7620 487 SUPERFAMILY SSF55920 220 482 9.81E-71 T 10-11-2016 IPR000994 Peptidase M24, structural domain A4G23_RS13830 93aa9d227f833eb3092c910e369a7620 487 SUPERFAMILY SSF53092 53 219 8.89E-26 T 10-11-2016 IPR028980 Creatinase/Aminopeptidase P, N-terminal A4G23_RS13830 93aa9d227f833eb3092c910e369a7620 487 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 395 407 - T 10-11-2016 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site A4G23_RS13830 93aa9d227f833eb3092c910e369a7620 487 Gene3D G3DSA:3.40.350.10 53 222 3.9E-36 T 10-11-2016 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A4G23_RS13830 93aa9d227f833eb3092c910e369a7620 487 Pfam PF00557 Metallopeptidase family M24 227 461 1.7E-52 T 10-11-2016 IPR000994 Peptidase M24, structural domain A4G23_RS21810 97c5a7eac9e9eb6e0ea7834d0f8ad788 1131 Gene3D G3DSA:1.10.10.10 32 98 2.9E-4 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS21810 97c5a7eac9e9eb6e0ea7834d0f8ad788 1131 SUPERFAMILY SSF52540 327 597 2.1E-23 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS21810 97c5a7eac9e9eb6e0ea7834d0f8ad788 1131 SUPERFAMILY SSF46894 5 97 1.08E-6 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS21810 97c5a7eac9e9eb6e0ea7834d0f8ad788 1131 Pfam PF13401 AAA domain 352 461 2.4E-9 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS21810 97c5a7eac9e9eb6e0ea7834d0f8ad788 1131 SUPERFAMILY SSF48452 99 269 2.48E-33 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS21810 97c5a7eac9e9eb6e0ea7834d0f8ad788 1131 Gene3D G3DSA:1.25.40.10 810 1049 3.1E-10 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS21810 97c5a7eac9e9eb6e0ea7834d0f8ad788 1131 Pfam PF00486 Transcriptional regulatory protein, C terminal 32 85 1.3E-4 T 10-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4G23_RS21810 97c5a7eac9e9eb6e0ea7834d0f8ad788 1131 SMART SM00862 19 97 0.0069 T 10-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4G23_RS21810 97c5a7eac9e9eb6e0ea7834d0f8ad788 1131 Gene3D G3DSA:3.40.50.300 342 465 1.6E-6 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS21810 97c5a7eac9e9eb6e0ea7834d0f8ad788 1131 PRINTS PR00364 Disease resistance protein signature 430 444 1.4E-8 T 10-11-2016 A4G23_RS21810 97c5a7eac9e9eb6e0ea7834d0f8ad788 1131 PRINTS PR00364 Disease resistance protein signature 533 547 1.4E-8 T 10-11-2016 A4G23_RS21810 97c5a7eac9e9eb6e0ea7834d0f8ad788 1131 PRINTS PR00364 Disease resistance protein signature 354 369 1.4E-8 T 10-11-2016 A4G23_RS21810 97c5a7eac9e9eb6e0ea7834d0f8ad788 1131 SMART SM01043 104 249 2.5E-46 T 10-11-2016 IPR005158 Bacterial transcriptional activator domain A4G23_RS21810 97c5a7eac9e9eb6e0ea7834d0f8ad788 1131 Pfam PF03704 Bacterial transcriptional activator domain 104 247 9.0E-39 T 10-11-2016 IPR005158 Bacterial transcriptional activator domain A4G23_RS18875 808fa669eddc2bc97e6d9897d2c38796 649 Gene3D G3DSA:1.25.40.10 58 216 5.0E-22 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS18875 808fa669eddc2bc97e6d9897d2c38796 649 Gene3D G3DSA:1.25.40.10 253 436 7.6E-39 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS18875 808fa669eddc2bc97e6d9897d2c38796 649 Gene3D G3DSA:1.25.40.10 440 644 6.5E-36 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS18875 808fa669eddc2bc97e6d9897d2c38796 649 SMART SM00028 598 631 110.0 T 10-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 A4G23_RS18875 808fa669eddc2bc97e6d9897d2c38796 649 SMART SM00028 361 394 37.0 T 10-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 A4G23_RS18875 808fa669eddc2bc97e6d9897d2c38796 649 SMART SM00028 425 458 120.0 T 10-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 A4G23_RS18875 808fa669eddc2bc97e6d9897d2c38796 649 SMART SM00028 534 567 98.0 T 10-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 A4G23_RS18875 808fa669eddc2bc97e6d9897d2c38796 649 SMART SM00028 77 110 180.0 T 10-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 A4G23_RS18875 808fa669eddc2bc97e6d9897d2c38796 649 SUPERFAMILY SSF81901 254 368 1.57E-17 T 10-11-2016 A4G23_RS18875 808fa669eddc2bc97e6d9897d2c38796 649 SUPERFAMILY SSF81901 335 496 8.02E-26 T 10-11-2016 A4G23_RS18875 808fa669eddc2bc97e6d9897d2c38796 649 SUPERFAMILY SSF81901 68 176 3.75E-15 T 10-11-2016 A4G23_RS18875 808fa669eddc2bc97e6d9897d2c38796 649 Pfam PF08238 Sel1 repeat 426 456 0.0054 T 10-11-2016 IPR006597 Sel1-like repeat A4G23_RS18875 808fa669eddc2bc97e6d9897d2c38796 649 Pfam PF08238 Sel1 repeat 281 295 52.0 T 10-11-2016 IPR006597 Sel1-like repeat A4G23_RS18875 808fa669eddc2bc97e6d9897d2c38796 649 Pfam PF08238 Sel1 repeat 254 264 15.0 T 10-11-2016 IPR006597 Sel1-like repeat A4G23_RS18875 808fa669eddc2bc97e6d9897d2c38796 649 Pfam PF08238 Sel1 repeat 299 328 13.0 T 10-11-2016 IPR006597 Sel1-like repeat A4G23_RS18875 808fa669eddc2bc97e6d9897d2c38796 649 Pfam PF08238 Sel1 repeat 408 424 6.3 T 10-11-2016 IPR006597 Sel1-like repeat A4G23_RS18875 808fa669eddc2bc97e6d9897d2c38796 649 Pfam PF08238 Sel1 repeat 548 565 0.4 T 10-11-2016 IPR006597 Sel1-like repeat A4G23_RS18875 808fa669eddc2bc97e6d9897d2c38796 649 Pfam PF08238 Sel1 repeat 489 533 9.2E-5 T 10-11-2016 IPR006597 Sel1-like repeat A4G23_RS18875 808fa669eddc2bc97e6d9897d2c38796 649 Pfam PF08238 Sel1 repeat 141 172 0.11 T 10-11-2016 IPR006597 Sel1-like repeat A4G23_RS18875 808fa669eddc2bc97e6d9897d2c38796 649 Pfam PF13374 Tetratricopeptide repeat 77 103 0.0034 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS18875 808fa669eddc2bc97e6d9897d2c38796 649 SUPERFAMILY SSF81901 519 631 2.35E-20 T 10-11-2016 A4G23_RS18875 808fa669eddc2bc97e6d9897d2c38796 649 Pfam PF13432 Tetratricopeptide repeat 334 389 0.0014 T 10-11-2016 A4G23_RS18875 808fa669eddc2bc97e6d9897d2c38796 649 Pfam PF13432 Tetratricopeptide repeat 571 630 0.0073 T 10-11-2016 A4G23_RS18875 808fa669eddc2bc97e6d9897d2c38796 649 SMART SM00671 265 296 48.0 T 10-11-2016 IPR006597 Sel1-like repeat A4G23_RS18875 808fa669eddc2bc97e6d9897d2c38796 649 SMART SM00671 489 533 62.0 T 10-11-2016 IPR006597 Sel1-like repeat A4G23_RS18875 808fa669eddc2bc97e6d9897d2c38796 649 SMART SM00671 109 140 170.0 T 10-11-2016 IPR006597 Sel1-like repeat A4G23_RS18875 808fa669eddc2bc97e6d9897d2c38796 649 SMART SM00671 361 392 7.8 T 10-11-2016 IPR006597 Sel1-like repeat A4G23_RS18875 808fa669eddc2bc97e6d9897d2c38796 649 SMART SM00671 329 360 24.0 T 10-11-2016 IPR006597 Sel1-like repeat A4G23_RS18875 808fa669eddc2bc97e6d9897d2c38796 649 SMART SM00671 77 108 130.0 T 10-11-2016 IPR006597 Sel1-like repeat A4G23_RS18875 808fa669eddc2bc97e6d9897d2c38796 649 SMART SM00671 425 456 0.0035 T 10-11-2016 IPR006597 Sel1-like repeat A4G23_RS18875 808fa669eddc2bc97e6d9897d2c38796 649 SMART SM00671 141 172 0.04 T 10-11-2016 IPR006597 Sel1-like repeat A4G23_RS18875 808fa669eddc2bc97e6d9897d2c38796 649 SMART SM00671 173 203 340.0 T 10-11-2016 IPR006597 Sel1-like repeat A4G23_RS18875 808fa669eddc2bc97e6d9897d2c38796 649 SMART SM00671 534 565 4.3 T 10-11-2016 IPR006597 Sel1-like repeat A4G23_RS18875 808fa669eddc2bc97e6d9897d2c38796 649 SMART SM00671 566 597 3.3 T 10-11-2016 IPR006597 Sel1-like repeat A4G23_RS18875 808fa669eddc2bc97e6d9897d2c38796 649 SMART SM00671 297 328 5.5 T 10-11-2016 IPR006597 Sel1-like repeat A4G23_RS18875 808fa669eddc2bc97e6d9897d2c38796 649 SMART SM00671 393 424 7.1 T 10-11-2016 IPR006597 Sel1-like repeat A4G23_RS10930 6c7dbb3d316f07695f3550402d3a04cc 163 SUPERFAMILY SSF81330 18 120 1.44E-23 T 10-11-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 A4G23_RS10930 6c7dbb3d316f07695f3550402d3a04cc 163 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 9 146 1.0E-32 T 10-11-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 A4G23_RS10930 6c7dbb3d316f07695f3550402d3a04cc 163 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 19 32 - T 10-11-2016 IPR019823 Large-conductance mechanosensitive channel, conserved site A4G23_RS10930 6c7dbb3d316f07695f3550402d3a04cc 163 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 10 149 6.7E-22 T 10-11-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 A4G23_RS10385 3ab90a4c84d60422190c30ce900828bf 431 Gene3D G3DSA:3.30.390.10 6 127 1.0E-52 T 10-11-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4G23_RS10385 3ab90a4c84d60422190c30ce900828bf 431 Pfam PF03952 Enolase, N-terminal domain 6 136 3.4E-55 T 10-11-2016 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4G23_RS10385 3ab90a4c84d60422190c30ce900828bf 431 Hamap MF_00318 Enolase [eno]. 4 411 45.437 T 10-11-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4G23_RS10385 3ab90a4c84d60422190c30ce900828bf 431 PRINTS PR00148 Enolase signature 109 125 3.0E-47 T 10-11-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4G23_RS10385 3ab90a4c84d60422190c30ce900828bf 431 PRINTS PR00148 Enolase signature 163 176 3.0E-47 T 10-11-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4G23_RS10385 3ab90a4c84d60422190c30ce900828bf 431 PRINTS PR00148 Enolase signature 363 380 3.0E-47 T 10-11-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4G23_RS10385 3ab90a4c84d60422190c30ce900828bf 431 PRINTS PR00148 Enolase signature 39 53 3.0E-47 T 10-11-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4G23_RS10385 3ab90a4c84d60422190c30ce900828bf 431 PRINTS PR00148 Enolase signature 334 348 3.0E-47 T 10-11-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4G23_RS10385 3ab90a4c84d60422190c30ce900828bf 431 PRINTS PR00148 Enolase signature 311 322 3.0E-47 T 10-11-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4G23_RS10385 3ab90a4c84d60422190c30ce900828bf 431 SMART SM01192 141 425 9.5E-232 T 10-11-2016 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4G23_RS10385 3ab90a4c84d60422190c30ce900828bf 431 SMART SM01193 6 136 5.0E-87 T 10-11-2016 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4G23_RS10385 3ab90a4c84d60422190c30ce900828bf 431 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 6 425 2.1E-206 T 10-11-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4G23_RS10385 3ab90a4c84d60422190c30ce900828bf 431 SUPERFAMILY SSF51604 140 425 1.1E-133 T 10-11-2016 IPR029065 Enolase C-terminal domain-like A4G23_RS10385 3ab90a4c84d60422190c30ce900828bf 431 SUPERFAMILY SSF54826 6 140 7.38E-52 T 10-11-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4G23_RS10385 3ab90a4c84d60422190c30ce900828bf 431 Pfam PF00113 Enolase, C-terminal TIM barrel domain 142 422 1.6E-134 T 10-11-2016 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4G23_RS10385 3ab90a4c84d60422190c30ce900828bf 431 PIRSF PIRSF001400 3 424 1.1E-189 T 10-11-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4G23_RS10385 3ab90a4c84d60422190c30ce900828bf 431 Gene3D G3DSA:3.20.20.120 130 423 2.4E-139 T 10-11-2016 IPR029065 Enolase C-terminal domain-like A4G23_RS10385 3ab90a4c84d60422190c30ce900828bf 431 ProSitePatterns PS00164 Enolase signature. 334 347 - T 10-11-2016 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4G23_RS02840 36cb82f61950acd51726e4ca6c78432b 137 SUPERFAMILY SSF51735 17 135 7.88E-39 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS02840 36cb82f61950acd51726e4ca6c78432b 137 SMART SM00881 12 105 5.7E-20 T 10-11-2016 IPR003781 CoA-binding GO:0048037 A4G23_RS02840 36cb82f61950acd51726e4ca6c78432b 137 Pfam PF13380 CoA binding domain 18 131 4.4E-38 T 10-11-2016 IPR003781 CoA-binding GO:0048037 A4G23_RS02840 36cb82f61950acd51726e4ca6c78432b 137 Gene3D G3DSA:3.40.50.720 5 135 1.6E-42 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS20785 c531f0db54da7d4bdbc62894a16501d7 162 SUPERFAMILY SSF160904 3 160 1.02E-34 T 10-11-2016 A4G23_RS20785 c531f0db54da7d4bdbc62894a16501d7 162 Pfam PF07336 Putative stress-induced transcription regulator 3 118 1.4E-17 T 10-11-2016 IPR010852 Putative stress-induced transcription regulator A4G23_RS20785 c531f0db54da7d4bdbc62894a16501d7 162 Gene3D G3DSA:1.10.3300.10 4 161 2.3E-32 T 10-11-2016 IPR023286 ABATE domain A4G23_RS20785 c531f0db54da7d4bdbc62894a16501d7 162 Pfam PF11706 CGNR zinc finger 122 161 2.0E-7 T 10-11-2016 IPR021005 Zinc finger, CGNR A4G23_RS20445 bd0bcfe1f46a172e90acc9f43978974d 1325 Pfam PF06470 SMC proteins Flexible Hinge Domain 512 586 1.1E-12 T 10-11-2016 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 A4G23_RS20445 bd0bcfe1f46a172e90acc9f43978974d 1325 SUPERFAMILY SSF75553 653 754 5.89E-23 T 10-11-2016 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 A4G23_RS20445 bd0bcfe1f46a172e90acc9f43978974d 1325 SUPERFAMILY SSF75553 495 571 5.89E-23 T 10-11-2016 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 A4G23_RS20445 bd0bcfe1f46a172e90acc9f43978974d 1325 SUPERFAMILY SSF52540 2 207 8.19E-72 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS20445 bd0bcfe1f46a172e90acc9f43978974d 1325 SUPERFAMILY SSF52540 1126 1316 8.19E-72 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS20445 bd0bcfe1f46a172e90acc9f43978974d 1325 SMART SM00968 512 709 3.0E-23 T 10-11-2016 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 A4G23_RS20445 bd0bcfe1f46a172e90acc9f43978974d 1325 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 1317 4.1E-70 T 10-11-2016 IPR003395 RecF/RecN/SMC, N-terminal A4G23_RS20445 bd0bcfe1f46a172e90acc9f43978974d 1325 Gene3D G3DSA:3.40.50.300 2 163 1.0E-86 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS20445 bd0bcfe1f46a172e90acc9f43978974d 1325 Gene3D G3DSA:3.40.50.300 1173 1321 1.0E-86 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS20445 bd0bcfe1f46a172e90acc9f43978974d 1325 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1325 22.836 T 10-11-2016 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 A4G23_RS23770 bf45cac0f929aad38092f6b1b5f6cf4e 478 SUPERFAMILY SSF103473 446 474 1.96E-65 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS23770 bf45cac0f929aad38092f6b1b5f6cf4e 478 SUPERFAMILY SSF103473 2 166 1.96E-65 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS23770 bf45cac0f929aad38092f6b1b5f6cf4e 478 SUPERFAMILY SSF103473 218 389 1.96E-65 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS23770 bf45cac0f929aad38092f6b1b5f6cf4e 478 Gene3D G3DSA:1.20.1250.20 2 160 2.6E-31 T 10-11-2016 A4G23_RS23770 bf45cac0f929aad38092f6b1b5f6cf4e 478 Gene3D G3DSA:1.20.1250.20 446 467 3.0E-20 T 10-11-2016 A4G23_RS23770 bf45cac0f929aad38092f6b1b5f6cf4e 478 Gene3D G3DSA:1.20.1250.20 233 389 3.0E-20 T 10-11-2016 A4G23_RS23770 bf45cac0f929aad38092f6b1b5f6cf4e 478 Pfam PF07690 Major Facilitator Superfamily 3 379 1.8E-55 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS23770 bf45cac0f929aad38092f6b1b5f6cf4e 478 PRINTS PR01036 Tetracycline resistance protein TetB signature 107 131 6.5E-7 T 10-11-2016 A4G23_RS23770 bf45cac0f929aad38092f6b1b5f6cf4e 478 PRINTS PR01036 Tetracycline resistance protein TetB signature 77 97 6.5E-7 T 10-11-2016 A4G23_RS23770 bf45cac0f929aad38092f6b1b5f6cf4e 478 PRINTS PR01036 Tetracycline resistance protein TetB signature 272 296 6.5E-7 T 10-11-2016 A4G23_RS03315 96089c07ae5a82379966a37c98879230 378 Gene3D G3DSA:3.60.15.10 200 275 1.8E-5 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS03315 96089c07ae5a82379966a37c98879230 378 SUPERFAMILY SSF56281 154 325 6.46E-9 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS06000 b5bfb11216fde3447483cfbf5ea37010 269 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 51 68 - T 10-11-2016 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 A4G23_RS06000 b5bfb11216fde3447483cfbf5ea37010 269 Gene3D G3DSA:3.20.20.70 2 259 6.0E-96 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS06000 b5bfb11216fde3447483cfbf5ea37010 269 Hamap MF_00134_A Indole-3-glycerol phosphate synthase [trpC]. 34 253 29.374 T 10-11-2016 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 A4G23_RS06000 b5bfb11216fde3447483cfbf5ea37010 269 SUPERFAMILY SSF51366 12 257 7.16E-79 T 10-11-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 A4G23_RS06000 b5bfb11216fde3447483cfbf5ea37010 269 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 2 257 34.173 T 10-11-2016 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 A4G23_RS06000 b5bfb11216fde3447483cfbf5ea37010 269 Pfam PF00218 Indole-3-glycerol phosphate synthase 4 255 1.4E-80 T 10-11-2016 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 A4G23_RS21890 e4d8343e361adcecc777c2f239231355 372 SMART SM00244 21 179 2.5E-53 T 10-11-2016 IPR001107 Band 7 domain A4G23_RS21890 e4d8343e361adcecc777c2f239231355 372 ProSitePatterns PS01270 Band 7 protein family signature. 135 163 - T 10-11-2016 IPR018080 Band 7/stomatin-like, conserved site A4G23_RS21890 e4d8343e361adcecc777c2f239231355 372 SUPERFAMILY SSF117892 52 186 1.57E-39 T 10-11-2016 IPR001107 Band 7 domain A4G23_RS21890 e4d8343e361adcecc777c2f239231355 372 Pfam PF01145 SPFH domain / Band 7 family 25 195 2.3E-37 T 10-11-2016 IPR001107 Band 7 domain A4G23_RS21890 e4d8343e361adcecc777c2f239231355 372 PRINTS PR00721 Stomatin signature 174 195 4.6E-31 T 10-11-2016 IPR001972 Stomatin family GO:0016020 A4G23_RS21890 e4d8343e361adcecc777c2f239231355 372 PRINTS PR00721 Stomatin signature 111 128 4.6E-31 T 10-11-2016 IPR001972 Stomatin family GO:0016020 A4G23_RS21890 e4d8343e361adcecc777c2f239231355 372 PRINTS PR00721 Stomatin signature 131 154 4.6E-31 T 10-11-2016 IPR001972 Stomatin family GO:0016020 A4G23_RS21890 e4d8343e361adcecc777c2f239231355 372 PRINTS PR00721 Stomatin signature 76 97 4.6E-31 T 10-11-2016 IPR001972 Stomatin family GO:0016020 A4G23_RS21890 e4d8343e361adcecc777c2f239231355 372 PRINTS PR00721 Stomatin signature 155 173 4.6E-31 T 10-11-2016 IPR001972 Stomatin family GO:0016020 A4G23_RS02340 bbfbbfb8cd4f28e17916ec05b57c46c5 207 PIRSF PIRSF004682 1 193 5.2E-55 T 10-11-2016 IPR004446 D,D-heptose 1,7-bisphosphate phosphatase GO:0005975|GO:0016791 A4G23_RS02340 bbfbbfb8cd4f28e17916ec05b57c46c5 207 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 6 153 5.0E-32 T 10-11-2016 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 A4G23_RS02340 bbfbbfb8cd4f28e17916ec05b57c46c5 207 SUPERFAMILY SSF56784 3 180 3.41E-48 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS02340 bbfbbfb8cd4f28e17916ec05b57c46c5 207 Pfam PF13242 HAD-hyrolase-like 108 176 4.6E-12 T 10-11-2016 A4G23_RS02340 bbfbbfb8cd4f28e17916ec05b57c46c5 207 Gene3D G3DSA:3.40.50.1000 2 181 3.2E-55 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS02340 bbfbbfb8cd4f28e17916ec05b57c46c5 207 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 6 150 2.3E-41 T 10-11-2016 IPR006543 Histidinol-phosphate phosphatase GO:0016791 A4G23_RS25390 4c06faa32757a165efc9f4bf44fcae5f 503 TIGRFAM TIGR04367 HpnR_B12_rSAM: hopanoid C-3 methylase HpnR 1 486 4.5E-257 T 10-11-2016 IPR027564 Hopanoid C-3 methylase HpnR A4G23_RS25390 4c06faa32757a165efc9f4bf44fcae5f 503 SUPERFAMILY SSF102114 156 381 7.32E-29 T 10-11-2016 A4G23_RS25390 4c06faa32757a165efc9f4bf44fcae5f 503 SUPERFAMILY SSF52242 23 127 1.88E-6 T 10-11-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A4G23_RS25390 4c06faa32757a165efc9f4bf44fcae5f 503 Gene3D G3DSA:3.80.30.20 185 376 1.2E-24 T 10-11-2016 IPR023404 Radical SAM, alpha/beta horseshoe A4G23_RS25390 4c06faa32757a165efc9f4bf44fcae5f 503 SMART SM00729 184 380 2.2E-15 T 10-11-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 A4G23_RS25390 4c06faa32757a165efc9f4bf44fcae5f 503 Pfam PF02310 B12 binding domain 18 128 5.8E-21 T 10-11-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A4G23_RS25390 4c06faa32757a165efc9f4bf44fcae5f 503 Pfam PF04055 Radical SAM superfamily 188 347 2.0E-13 T 10-11-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 A4G23_RS03580 d9fe84170e6540959229143b0d9c6d91 142 Pfam PF01029 NusB family 6 133 3.1E-34 T 10-11-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 A4G23_RS03580 d9fe84170e6540959229143b0d9c6d91 142 SUPERFAMILY SSF48013 4 131 5.49E-39 T 10-11-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 A4G23_RS03580 d9fe84170e6540959229143b0d9c6d91 142 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 2 137 22.233 T 10-11-2016 IPR011605 NusB antitermination factor GO:0006353 A4G23_RS03580 d9fe84170e6540959229143b0d9c6d91 142 Gene3D G3DSA:1.10.940.10 2 132 3.2E-43 T 10-11-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 A4G23_RS03580 d9fe84170e6540959229143b0d9c6d91 142 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 4 134 3.8E-39 T 10-11-2016 IPR011605 NusB antitermination factor GO:0006353 A4G23_RS05785 e0693840e29c2159ca69d8479f860b8c 221 Pfam PF01638 HxlR-like helix-turn-helix 29 110 1.7E-21 T 10-11-2016 IPR002577 Helix-turn-helix, HxlR type A4G23_RS05785 e0693840e29c2159ca69d8479f860b8c 221 SUPERFAMILY SSF55718 136 215 4.47E-7 T 10-11-2016 IPR003033 SCP2 sterol-binding domain A4G23_RS05785 e0693840e29c2159ca69d8479f860b8c 221 SUPERFAMILY SSF46785 15 121 2.06E-28 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS05785 e0693840e29c2159ca69d8479f860b8c 221 Gene3D G3DSA:1.10.10.10 9 112 5.2E-32 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS27205 a858b8358db1f69b2f9735e9da679d07 496 Gene3D G3DSA:1.10.1200.10 6 77 1.4E-14 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS27205 a858b8358db1f69b2f9735e9da679d07 496 SUPERFAMILY SSF52777 99 257 4.82E-24 T 10-11-2016 A4G23_RS27205 a858b8358db1f69b2f9735e9da679d07 496 ProSitePatterns PS00012 Phosphopantetheine attachment site. 33 48 - T 10-11-2016 IPR006162 Phosphopantetheine attachment site A4G23_RS27205 a858b8358db1f69b2f9735e9da679d07 496 SUPERFAMILY SSF47336 6 88 5.04E-12 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS27205 a858b8358db1f69b2f9735e9da679d07 496 Pfam PF00668 Condensation domain 201 375 1.2E-17 T 10-11-2016 IPR001242 Condensation domain A4G23_RS27205 a858b8358db1f69b2f9735e9da679d07 496 Pfam PF00668 Condensation domain 104 174 1.3E-6 T 10-11-2016 IPR001242 Condensation domain A4G23_RS27205 a858b8358db1f69b2f9735e9da679d07 496 Pfam PF00550 Phosphopantetheine attachment site 6 73 1.8E-10 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS27205 a858b8358db1f69b2f9735e9da679d07 496 Gene3D G3DSA:3.30.559.10 194 260 4.7E-4 T 10-11-2016 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 A4G23_RS27205 a858b8358db1f69b2f9735e9da679d07 496 SUPERFAMILY SSF52777 268 494 9.89E-27 T 10-11-2016 A4G23_RS22420 f148340849f2d215221d3fe8fcfa3c00 56 TIGRFAM TIGR03892 thiopep_precurs: thiazolylpeptide-type bacteriocin precursor 13 54 3.8E-11 T 10-11-2016 IPR023895 Thiazolylpeptide-type bacteriocin precursor A4G23_RS17695 a5381b1a1193887efecbe1c956142cdb 498 SUPERFAMILY SSF53720 33 489 8.38E-164 T 10-11-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A4G23_RS17695 a5381b1a1193887efecbe1c956142cdb 498 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 298 309 - T 10-11-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 A4G23_RS17695 a5381b1a1193887efecbe1c956142cdb 498 Pfam PF00171 Aldehyde dehydrogenase family 45 490 5.0E-166 T 10-11-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A4G23_RS17695 a5381b1a1193887efecbe1c956142cdb 498 Gene3D G3DSA:3.40.605.10 35 284 4.1E-100 T 10-11-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A4G23_RS17695 a5381b1a1193887efecbe1c956142cdb 498 Gene3D G3DSA:3.40.309.10 285 469 4.4E-63 T 10-11-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 A4G23_RS12205 35d3a7732c7dcfb77f7c394e8720fbbe 226 SUPERFAMILY SSF46894 126 225 6.24E-32 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS12205 35d3a7732c7dcfb77f7c394e8720fbbe 226 Gene3D G3DSA:1.10.10.10 126 225 5.1E-37 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS12205 35d3a7732c7dcfb77f7c394e8720fbbe 226 SMART SM00448 2 112 4.0E-45 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS12205 35d3a7732c7dcfb77f7c394e8720fbbe 226 SUPERFAMILY SSF52172 3 123 3.13E-41 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS12205 35d3a7732c7dcfb77f7c394e8720fbbe 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 224 1.0E-27 T 10-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4G23_RS12205 35d3a7732c7dcfb77f7c394e8720fbbe 226 Pfam PF00072 Response regulator receiver domain 4 113 4.1E-28 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS12205 35d3a7732c7dcfb77f7c394e8720fbbe 226 Gene3D G3DSA:3.40.50.2300 3 122 2.3E-40 T 10-11-2016 A4G23_RS12205 35d3a7732c7dcfb77f7c394e8720fbbe 226 SMART SM00862 148 224 2.1E-30 T 10-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4G23_RS17045 52d7ab4bc0257121d884ad105bc97dbb 157 Pfam PF14433 SUKH-3 immunity protein 8 146 3.1E-25 T 10-11-2016 IPR025850 SUKH-3 immunity protein A4G23_RS03205 f1ed60ba72b7fb13b08c862f7b5defab 254 Pfam PF03746 LamB/YcsF family 6 244 1.6E-96 T 10-11-2016 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF A4G23_RS03205 f1ed60ba72b7fb13b08c862f7b5defab 254 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 4 248 42.712 T 10-11-2016 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF A4G23_RS03205 f1ed60ba72b7fb13b08c862f7b5defab 254 SUPERFAMILY SSF88713 5 253 4.45E-93 T 10-11-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A4G23_RS26325 30d6be768e540ea0f11c756927dda5cc 306 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 50 63 - T 10-11-2016 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 A4G23_RS26325 30d6be768e540ea0f11c756927dda5cc 306 Gene3D G3DSA:3.40.50.1100 74 305 9.7E-59 T 10-11-2016 A4G23_RS26325 30d6be768e540ea0f11c756927dda5cc 306 SUPERFAMILY SSF53686 10 305 5.89E-73 T 10-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4G23_RS26325 30d6be768e540ea0f11c756927dda5cc 306 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 24 302 7.9E-71 T 10-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4G23_RS04335 c63145bdaf5f44b865001e5b779e9e4e 415 SMART SM00116 356 404 5.4 T 10-11-2016 IPR000644 CBS domain A4G23_RS04335 c63145bdaf5f44b865001e5b779e9e4e 415 SMART SM00116 291 339 2.4 T 10-11-2016 IPR000644 CBS domain A4G23_RS04335 c63145bdaf5f44b865001e5b779e9e4e 415 SUPERFAMILY SSF54631 288 405 4.01E-13 T 10-11-2016 A4G23_RS04335 c63145bdaf5f44b865001e5b779e9e4e 415 PIRSF PIRSF006404 33 413 2.9E-105 T 10-11-2016 IPR016483 Uncharacterised conserved protein UCP006404, peptidase M50/CBS A4G23_RS04335 c63145bdaf5f44b865001e5b779e9e4e 415 Gene3D G3DSA:3.10.580.10 288 403 3.4E-12 T 10-11-2016 A4G23_RS04335 c63145bdaf5f44b865001e5b779e9e4e 415 Pfam PF00571 CBS domain 289 334 3.3E-4 T 10-11-2016 IPR000644 CBS domain A4G23_RS04335 c63145bdaf5f44b865001e5b779e9e4e 415 Pfam PF02163 Peptidase family M50 168 224 8.2E-7 T 10-11-2016 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033 A4G23_RS00445 d84f6786e79c9f9e1cffbd5f9df9d1f3 798 ProSitePatterns PS60002 Phosphoketolase signature 1. 142 148 - T 10-11-2016 IPR019790 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, conserved site GO:0005975|GO:0016832 A4G23_RS00445 d84f6786e79c9f9e1cffbd5f9df9d1f3 798 PIRSF PIRSF017245 2 798 0.0 T 10-11-2016 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 A4G23_RS00445 d84f6786e79c9f9e1cffbd5f9df9d1f3 798 SUPERFAMILY SSF52518 2 377 1.56E-72 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS00445 d84f6786e79c9f9e1cffbd5f9df9d1f3 798 ProSitePatterns PS60003 Phosphoketolase signature 2. 155 173 - T 10-11-2016 IPR019789 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, thiamine diphosphate binding site GO:0005975|GO:0016832 A4G23_RS00445 d84f6786e79c9f9e1cffbd5f9df9d1f3 798 Gene3D G3DSA:3.40.50.970 52 255 2.1E-20 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS00445 d84f6786e79c9f9e1cffbd5f9df9d1f3 798 Pfam PF09364 XFP N-terminal domain 7 392 2.7E-175 T 10-11-2016 IPR018970 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, N-terminal A4G23_RS00445 d84f6786e79c9f9e1cffbd5f9df9d1f3 798 Pfam PF09363 XFP C-terminal domain 594 796 2.2E-84 T 10-11-2016 IPR018969 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, C-terminal GO:0005975|GO:0016832 A4G23_RS00445 d84f6786e79c9f9e1cffbd5f9df9d1f3 798 Pfam PF03894 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 407 583 1.5E-85 T 10-11-2016 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 A4G23_RS00445 d84f6786e79c9f9e1cffbd5f9df9d1f3 798 Hamap MF_01403 Probable phosphoketolase. 3 798 40.397 T 10-11-2016 IPR023962 Probable phosphoketolase A4G23_RS00445 d84f6786e79c9f9e1cffbd5f9df9d1f3 798 SUPERFAMILY SSF52518 390 596 4.41E-21 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS23305 df118381e20b3434d987c8e7b67afb22 580 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 172 1.4E-40 T 10-11-2016 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 A4G23_RS23305 df118381e20b3434d987c8e7b67afb22 580 SUPERFAMILY SSF52518 360 541 9.63E-60 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS23305 df118381e20b3434d987c8e7b67afb22 580 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 192 320 1.3E-29 T 10-11-2016 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 A4G23_RS23305 df118381e20b3434d987c8e7b67afb22 580 SUPERFAMILY SSF52518 4 175 1.31E-40 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS23305 df118381e20b3434d987c8e7b67afb22 580 Gene3D G3DSA:3.40.50.1220 186 342 2.4E-38 T 10-11-2016 IPR029035 DHS-like NAD/FAD-binding domain A4G23_RS23305 df118381e20b3434d987c8e7b67afb22 580 Gene3D G3DSA:3.40.50.970 356 548 1.3E-57 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS23305 df118381e20b3434d987c8e7b67afb22 580 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 383 529 7.5E-40 T 10-11-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A4G23_RS23305 df118381e20b3434d987c8e7b67afb22 580 SUPERFAMILY SSF52467 183 347 4.27E-40 T 10-11-2016 IPR029035 DHS-like NAD/FAD-binding domain A4G23_RS23305 df118381e20b3434d987c8e7b67afb22 580 Gene3D G3DSA:3.40.50.970 3 175 6.2E-50 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS02750 8f5ce2edfe54441209717e1845d6a4f3 489 SUPERFAMILY SSF48557 22 467 2.67E-79 T 10-11-2016 IPR008948 L-Aspartase-like GO:0003824 A4G23_RS02750 8f5ce2edfe54441209717e1845d6a4f3 489 Gene3D G3DSA:1.20.200.10 114 463 5.9E-80 T 10-11-2016 A4G23_RS02750 8f5ce2edfe54441209717e1845d6a4f3 489 Pfam PF10397 Adenylosuccinate lyase C-terminus 382 463 3.3E-12 T 10-11-2016 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4G23_RS02750 8f5ce2edfe54441209717e1845d6a4f3 489 Pfam PF00206 Lyase 66 313 3.2E-18 T 10-11-2016 IPR022761 Fumarate lyase, N-terminal A4G23_RS02750 8f5ce2edfe54441209717e1845d6a4f3 489 ProSitePatterns PS00163 Fumarate lyases signature. 292 301 - T 10-11-2016 IPR020557 Fumarate lyase, conserved site GO:0003824 A4G23_RS02750 8f5ce2edfe54441209717e1845d6a4f3 489 Gene3D G3DSA:1.10.275.10 25 113 6.5E-23 T 10-11-2016 IPR024083 Fumarase/histidase, N-terminal A4G23_RS02750 8f5ce2edfe54441209717e1845d6a4f3 489 SMART SM00998 381 467 4.3E-18 T 10-11-2016 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4G23_RS02750 8f5ce2edfe54441209717e1845d6a4f3 489 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 23 465 2.6E-125 T 10-11-2016 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4G23_RS02750 8f5ce2edfe54441209717e1845d6a4f3 489 PRINTS PR00149 Fumarate lyase superfamily signature 155 173 1.4E-10 T 10-11-2016 IPR000362 Fumarate lyase family A4G23_RS02750 8f5ce2edfe54441209717e1845d6a4f3 489 PRINTS PR00149 Fumarate lyase superfamily signature 292 308 1.4E-10 T 10-11-2016 IPR000362 Fumarate lyase family A4G23_RS02750 8f5ce2edfe54441209717e1845d6a4f3 489 PRINTS PR00149 Fumarate lyase superfamily signature 110 128 1.4E-10 T 10-11-2016 IPR000362 Fumarate lyase family A4G23_RS02750 8f5ce2edfe54441209717e1845d6a4f3 489 PRINTS PR00149 Fumarate lyase superfamily signature 249 276 1.4E-10 T 10-11-2016 IPR000362 Fumarate lyase family A4G23_RS06355 0693a0cb443969d644de344cd1a3ffc1 388 SUPERFAMILY SSF51905 1 107 2.39E-12 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS06355 0693a0cb443969d644de344cd1a3ffc1 388 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 129 147 1.5E-20 T 10-11-2016 A4G23_RS06355 0693a0cb443969d644de344cd1a3ffc1 388 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 210 226 1.5E-20 T 10-11-2016 A4G23_RS06355 0693a0cb443969d644de344cd1a3ffc1 388 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 85 103 1.5E-20 T 10-11-2016 A4G23_RS06355 0693a0cb443969d644de344cd1a3ffc1 388 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 237 259 1.5E-20 T 10-11-2016 A4G23_RS06355 0693a0cb443969d644de344cd1a3ffc1 388 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 88 97 3.9E-13 T 10-11-2016 A4G23_RS06355 0693a0cb443969d644de344cd1a3ffc1 388 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 129 154 3.9E-13 T 10-11-2016 A4G23_RS06355 0693a0cb443969d644de344cd1a3ffc1 388 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 211 225 3.9E-13 T 10-11-2016 A4G23_RS06355 0693a0cb443969d644de344cd1a3ffc1 388 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 252 259 3.9E-13 T 10-11-2016 A4G23_RS06355 0693a0cb443969d644de344cd1a3ffc1 388 Gene3D G3DSA:3.50.50.60 91 290 1.2E-48 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS06355 0693a0cb443969d644de344cd1a3ffc1 388 Gene3D G3DSA:3.50.50.60 1 90 1.1E-20 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS06355 0693a0cb443969d644de344cd1a3ffc1 388 SUPERFAMILY SSF51905 105 291 4.05E-38 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS06355 0693a0cb443969d644de344cd1a3ffc1 388 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 1 278 7.1E-55 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS06355 0693a0cb443969d644de344cd1a3ffc1 388 Gene3D G3DSA:3.30.390.30 302 387 8.4E-30 T 10-11-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A4G23_RS06355 0693a0cb443969d644de344cd1a3ffc1 388 Pfam PF14759 Reductase C-terminal 302 385 1.6E-25 T 10-11-2016 IPR028202 Reductase, C-terminal A4G23_RS06355 0693a0cb443969d644de344cd1a3ffc1 388 SUPERFAMILY SSF55424 295 387 8.51E-27 T 10-11-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 A4G23_RS21180 84399afeeb7c9f1cca73d5f9fb7e6efd 189 Gene3D G3DSA:1.10.10.10 30 74 8.0E-4 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS21180 84399afeeb7c9f1cca73d5f9fb7e6efd 189 Hamap MF_01114 Regulatory protein RecX [recX]. 10 177 15.383 T 10-11-2016 IPR003783 Regulatory protein RecX GO:0006282 A4G23_RS21180 84399afeeb7c9f1cca73d5f9fb7e6efd 189 Gene3D G3DSA:1.10.10.10 76 117 1.0E-6 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS21180 84399afeeb7c9f1cca73d5f9fb7e6efd 189 Pfam PF02631 RecX family 52 172 5.9E-28 T 10-11-2016 IPR003783 Regulatory protein RecX GO:0006282 A4G23_RS21180 84399afeeb7c9f1cca73d5f9fb7e6efd 189 SUPERFAMILY SSF51649 65 131 5.5E-5 T 10-11-2016 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A4G23_RS09385 d3745764f367b8e38a562a3539e9cd44 107 Pfam PF12277 Protein of unknown function (DUF3618) 4 49 1.5E-15 T 10-11-2016 IPR022062 Protein of unknown function DUF3618 A4G23_RS11475 7639695cda38c1ff9ad6449358e91e0c 272 SUPERFAMILY SSF52540 20 242 2.15E-59 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS11475 7639695cda38c1ff9ad6449358e91e0c 272 Pfam PF00005 ABC transporter 39 180 3.8E-26 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS11475 7639695cda38c1ff9ad6449358e91e0c 272 Gene3D G3DSA:3.40.50.300 18 240 8.4E-65 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS11475 7639695cda38c1ff9ad6449358e91e0c 272 SMART SM00382 46 242 1.0E-9 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS09320 142414ba3e647bfca82ceec49245aba0 236 Pfam PF02096 60Kd inner membrane protein 20 217 1.7E-32 T 10-11-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 A4G23_RS09320 142414ba3e647bfca82ceec49245aba0 236 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 20 217 1.2E-37 T 10-11-2016 IPR028055 Membrane insertase YidC/Oxa1, C-terminal A4G23_RS06815 c7f4a80eb719acf63afe867f54d43b74 244 SUPERFAMILY SSF46689 6 82 3.13E-19 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS06815 c7f4a80eb719acf63afe867f54d43b74 244 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 6.7E-7 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS06815 c7f4a80eb719acf63afe867f54d43b74 244 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 6.7E-7 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS06815 c7f4a80eb719acf63afe867f54d43b74 244 Gene3D G3DSA:1.10.357.10 5 200 6.8E-37 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS06815 c7f4a80eb719acf63afe867f54d43b74 244 ProSitePatterns PS01081 TetR-type HTH domain signature. 30 60 - T 10-11-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A4G23_RS06815 c7f4a80eb719acf63afe867f54d43b74 244 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 64 3.4E-15 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS16270 1055a90a3513ed8f54b12e019bb6b35a 218 SUPERFAMILY SSF51735 1 206 1.28E-36 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS16270 1055a90a3513ed8f54b12e019bb6b35a 218 Gene3D G3DSA:3.40.50.720 1 206 2.8E-42 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS16270 1055a90a3513ed8f54b12e019bb6b35a 218 Pfam PF13460 NAD(P)H-binding 7 192 3.1E-39 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS27255 4a9eaef1d5ce72ff8bc23c896eea1631 335 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 120 310 1.1E-7 T 10-11-2016 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 A4G23_RS27255 4a9eaef1d5ce72ff8bc23c896eea1631 335 Gene3D G3DSA:3.60.130.10 5 318 1.5E-27 T 10-11-2016 A4G23_RS27255 4a9eaef1d5ce72ff8bc23c896eea1631 335 SUPERFAMILY SSF51197 5 315 1.79E-25 T 10-11-2016 A4G23_RS20390 89c66f61a9e545e9e7e4b75a4286827b 776 SMART SM00487 276 478 5.0E-31 T 10-11-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4G23_RS20390 89c66f61a9e545e9e7e4b75a4286827b 776 Gene3D G3DSA:2.40.50.140 57 153 8.8E-15 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS20390 89c66f61a9e545e9e7e4b75a4286827b 776 Gene3D G3DSA:3.40.50.300 576 712 2.3E-45 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS20390 89c66f61a9e545e9e7e4b75a4286827b 776 Gene3D G3DSA:3.40.50.300 473 515 2.3E-45 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS20390 89c66f61a9e545e9e7e4b75a4286827b 776 SUPERFAMILY SSF52540 197 471 1.31E-56 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS20390 89c66f61a9e545e9e7e4b75a4286827b 776 Pfam PF00271 Helicase conserved C-terminal domain 592 663 1.4E-18 T 10-11-2016 IPR001650 Helicase, C-terminal A4G23_RS20390 89c66f61a9e545e9e7e4b75a4286827b 776 SUPERFAMILY SSF50249 24 192 9.25E-30 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS20390 89c66f61a9e545e9e7e4b75a4286827b 776 Pfam PF00270 DEAD/DEAH box helicase 302 454 9.8E-16 T 10-11-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A4G23_RS20390 89c66f61a9e545e9e7e4b75a4286827b 776 SUPERFAMILY SSF52540 580 676 1.33E-38 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS20390 89c66f61a9e545e9e7e4b75a4286827b 776 SUPERFAMILY SSF52540 410 515 1.33E-38 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS20390 89c66f61a9e545e9e7e4b75a4286827b 776 Gene3D G3DSA:3.40.50.300 267 472 1.2E-59 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS20390 89c66f61a9e545e9e7e4b75a4286827b 776 Pfam PF01336 OB-fold nucleic acid binding domain 70 150 3.6E-9 T 10-11-2016 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A4G23_RS20390 89c66f61a9e545e9e7e4b75a4286827b 776 SMART SM00490 579 664 3.3E-23 T 10-11-2016 IPR001650 Helicase, C-terminal A4G23_RS14935 7b1fb04fbce46cdcce336e49b5908dd6 743 Pfam PF00270 DEAD/DEAH box helicase 15 190 1.6E-24 T 10-11-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A4G23_RS14935 7b1fb04fbce46cdcce336e49b5908dd6 743 SUPERFAMILY SSF52540 241 376 3.36E-40 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS14935 7b1fb04fbce46cdcce336e49b5908dd6 743 SUPERFAMILY SSF52540 63 204 3.36E-40 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS14935 7b1fb04fbce46cdcce336e49b5908dd6 743 SMART SM00490 278 359 1.0E-16 T 10-11-2016 IPR001650 Helicase, C-terminal A4G23_RS14935 7b1fb04fbce46cdcce336e49b5908dd6 743 SMART SM00487 9 218 3.7E-29 T 10-11-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4G23_RS14935 7b1fb04fbce46cdcce336e49b5908dd6 743 Pfam PF09369 Domain of unknown function (DUF1998) 620 699 4.6E-19 T 10-11-2016 IPR018973 DEAD/DEAH-box helicase, putative A4G23_RS14935 7b1fb04fbce46cdcce336e49b5908dd6 743 Pfam PF00271 Helicase conserved C-terminal domain 248 359 4.3E-11 T 10-11-2016 IPR001650 Helicase, C-terminal A4G23_RS14935 7b1fb04fbce46cdcce336e49b5908dd6 743 TIGRFAM TIGR03817 DECH_helic: helicase/secretion neighborhood putative DEAH-box helicase 2 725 0.0 T 10-11-2016 IPR022307 DEAD/DEAH-box helicase, putative, actinobacteria A4G23_RS14935 7b1fb04fbce46cdcce336e49b5908dd6 743 Gene3D G3DSA:3.40.50.300 242 386 5.9E-20 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS14935 7b1fb04fbce46cdcce336e49b5908dd6 743 Gene3D G3DSA:3.40.50.300 1 192 9.7E-35 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS01230 cc15cfba813761744034ca9bb91e2e8e 151 SUPERFAMILY SSF51206 4 131 1.23E-14 T 10-11-2016 IPR018490 Cyclic nucleotide-binding-like A4G23_RS01230 cc15cfba813761744034ca9bb91e2e8e 151 Pfam PF00027 Cyclic nucleotide-binding domain 25 111 1.0E-6 T 10-11-2016 IPR000595 Cyclic nucleotide-binding domain A4G23_RS01230 cc15cfba813761744034ca9bb91e2e8e 151 Gene3D G3DSA:2.60.120.10 4 130 4.3E-12 T 10-11-2016 IPR014710 RmlC-like jelly roll fold A4G23_RS12220 a6ba3738b87f13bb397aa00c256f3fa2 683 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 7 117 5.5E-8 T 10-11-2016 IPR000014 PAS domain A4G23_RS12220 a6ba3738b87f13bb397aa00c256f3fa2 683 Pfam PF01590 GAF domain 188 293 5.4E-13 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS12220 a6ba3738b87f13bb397aa00c256f3fa2 683 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 351 550 3.1E-51 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS12220 a6ba3738b87f13bb397aa00c256f3fa2 683 Gene3D G3DSA:3.30.450.40 120 300 2.4E-37 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS12220 a6ba3738b87f13bb397aa00c256f3fa2 683 SMART SM00065 122 303 6.5E-8 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS12220 a6ba3738b87f13bb397aa00c256f3fa2 683 SUPERFAMILY SSF55785 8 117 1.13E-13 T 10-11-2016 IPR000014 PAS domain A4G23_RS12220 a6ba3738b87f13bb397aa00c256f3fa2 683 Gene3D G3DSA:3.30.450.20 1 110 5.6E-15 T 10-11-2016 A4G23_RS12220 a6ba3738b87f13bb397aa00c256f3fa2 683 Pfam PF13581 Histidine kinase-like ATPase domain 564 671 8.8E-8 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS12220 a6ba3738b87f13bb397aa00c256f3fa2 683 SUPERFAMILY SSF55781 190 297 6.98E-16 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS12220 a6ba3738b87f13bb397aa00c256f3fa2 683 SUPERFAMILY SSF55874 587 677 4.25E-6 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS12220 a6ba3738b87f13bb397aa00c256f3fa2 683 Pfam PF08448 PAS fold 1 111 2.1E-15 T 10-11-2016 IPR013656 PAS fold-4 A4G23_RS12220 a6ba3738b87f13bb397aa00c256f3fa2 683 SMART SM00331 321 550 8.8E-34 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS00630 24ed28c5f6ae06a959e37d63bbc0c574 874 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 40 - T 10-11-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 A4G23_RS00630 24ed28c5f6ae06a959e37d63bbc0c574 874 Gene3D G3DSA:1.10.510.10 83 269 4.7E-49 T 10-11-2016 A4G23_RS00630 24ed28c5f6ae06a959e37d63bbc0c574 874 SUPERFAMILY SSF48452 749 866 8.95E-18 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS00630 24ed28c5f6ae06a959e37d63bbc0c574 874 SUPERFAMILY SSF56112 4 298 2.7E-76 T 10-11-2016 IPR011009 Protein kinase-like domain A4G23_RS00630 24ed28c5f6ae06a959e37d63bbc0c574 874 SUPERFAMILY SSF48452 623 775 1.33E-20 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS00630 24ed28c5f6ae06a959e37d63bbc0c574 874 Pfam PF13374 Tetratricopeptide repeat 754 795 7.9E-8 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS00630 24ed28c5f6ae06a959e37d63bbc0c574 874 Pfam PF13424 Tetratricopeptide repeat 510 571 1.3E-7 T 10-11-2016 A4G23_RS00630 24ed28c5f6ae06a959e37d63bbc0c574 874 Pfam PF13424 Tetratricopeptide repeat 594 647 1.3E-8 T 10-11-2016 A4G23_RS00630 24ed28c5f6ae06a959e37d63bbc0c574 874 Pfam PF13424 Tetratricopeptide repeat 673 743 1.4E-12 T 10-11-2016 A4G23_RS00630 24ed28c5f6ae06a959e37d63bbc0c574 874 Pfam PF13424 Tetratricopeptide repeat 803 865 6.1E-16 T 10-11-2016 A4G23_RS00630 24ed28c5f6ae06a959e37d63bbc0c574 874 Gene3D G3DSA:3.30.200.20 4 82 3.1E-23 T 10-11-2016 A4G23_RS00630 24ed28c5f6ae06a959e37d63bbc0c574 874 SMART SM00220 11 279 6.6E-66 T 10-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4G23_RS00630 24ed28c5f6ae06a959e37d63bbc0c574 874 Gene3D G3DSA:1.25.40.10 639 865 1.9E-25 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS00630 24ed28c5f6ae06a959e37d63bbc0c574 874 Pfam PF00069 Protein kinase domain 11 269 1.7E-47 T 10-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4G23_RS00630 24ed28c5f6ae06a959e37d63bbc0c574 874 Gene3D G3DSA:1.25.40.10 542 638 1.9E-7 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS00630 24ed28c5f6ae06a959e37d63bbc0c574 874 SUPERFAMILY SSF48452 507 634 5.96E-11 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS16510 736f155c6e362038ab07d5159c0059d3 397 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 3.7E-59 T 10-11-2016 A4G23_RS16510 736f155c6e362038ab07d5159c0059d3 397 Gene3D G3DSA:3.40.50.300 5 213 6.6E-71 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS16510 736f155c6e362038ab07d5159c0059d3 397 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 147 2.0E-13 T 10-11-2016 IPR005225 Small GTP-binding protein domain GO:0005525 A4G23_RS16510 736f155c6e362038ab07d5159c0059d3 397 Pfam PF03143 Elongation factor Tu C-terminal domain 301 395 1.9E-33 T 10-11-2016 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal A4G23_RS16510 736f155c6e362038ab07d5159c0059d3 397 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 397 59.653 T 10-11-2016 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A4G23_RS16510 736f155c6e362038ab07d5159c0059d3 397 SUPERFAMILY SSF50447 207 304 4.91E-31 T 10-11-2016 IPR009000 Translation protein, beta-barrel domain A4G23_RS16510 736f155c6e362038ab07d5159c0059d3 397 SUPERFAMILY SSF50465 305 397 5.47E-36 T 10-11-2016 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal A4G23_RS16510 736f155c6e362038ab07d5159c0059d3 397 PRINTS PR00315 GTP-binding elongation factor signature 133 142 2.3E-24 T 10-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4G23_RS16510 736f155c6e362038ab07d5159c0059d3 397 PRINTS PR00315 GTP-binding elongation factor signature 60 68 2.3E-24 T 10-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4G23_RS16510 736f155c6e362038ab07d5159c0059d3 397 PRINTS PR00315 GTP-binding elongation factor signature 96 107 2.3E-24 T 10-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4G23_RS16510 736f155c6e362038ab07d5159c0059d3 397 PRINTS PR00315 GTP-binding elongation factor signature 14 27 2.3E-24 T 10-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4G23_RS16510 736f155c6e362038ab07d5159c0059d3 397 PRINTS PR00315 GTP-binding elongation factor signature 80 90 2.3E-24 T 10-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4G23_RS16510 736f155c6e362038ab07d5159c0059d3 397 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 2 397 7.9E-223 T 10-11-2016 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A4G23_RS16510 736f155c6e362038ab07d5159c0059d3 397 SUPERFAMILY SSF52540 6 221 5.77E-62 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS16510 736f155c6e362038ab07d5159c0059d3 397 Gene3D G3DSA:2.40.30.10 214 301 5.2E-37 T 10-11-2016 A4G23_RS16510 736f155c6e362038ab07d5159c0059d3 397 Pfam PF03144 Elongation factor Tu domain 2 227 296 4.5E-17 T 10-11-2016 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A4G23_RS16510 736f155c6e362038ab07d5159c0059d3 397 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 53 68 - T 10-11-2016 IPR031157 Tr-type G domain, conserved site A4G23_RS16510 736f155c6e362038ab07d5159c0059d3 397 Gene3D G3DSA:2.40.30.10 303 395 3.7E-46 T 10-11-2016 A4G23_RS12465 bdb2faa546474b272d3ddf0d4a3a396a 342 SMART SM00354 3 74 1.4E-26 T 10-11-2016 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4G23_RS12465 bdb2faa546474b272d3ddf0d4a3a396a 342 Pfam PF00356 Bacterial regulatory proteins, lacI family 7 51 7.6E-15 T 10-11-2016 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4G23_RS12465 bdb2faa546474b272d3ddf0d4a3a396a 342 Gene3D G3DSA:1.10.260.40 4 56 1.6E-23 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS12465 bdb2faa546474b272d3ddf0d4a3a396a 342 SUPERFAMILY SSF53822 64 338 1.73E-61 T 10-11-2016 IPR028082 Periplasmic binding protein-like I A4G23_RS12465 bdb2faa546474b272d3ddf0d4a3a396a 342 Pfam PF13377 Periplasmic binding protein-like domain 171 337 2.0E-30 T 10-11-2016 A4G23_RS12465 bdb2faa546474b272d3ddf0d4a3a396a 342 Gene3D G3DSA:3.40.50.2300 174 339 4.4E-49 T 10-11-2016 A4G23_RS12465 bdb2faa546474b272d3ddf0d4a3a396a 342 Gene3D G3DSA:3.40.50.2300 57 173 7.1E-39 T 10-11-2016 A4G23_RS12465 bdb2faa546474b272d3ddf0d4a3a396a 342 SUPERFAMILY SSF47413 3 62 1.13E-14 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS17945 fccc9e79b7e5f7eba106d59d8b5fed06 171 SUPERFAMILY SSF46785 37 152 6.39E-27 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS17945 fccc9e79b7e5f7eba106d59d8b5fed06 171 Pfam PF01047 MarR family 48 103 1.7E-13 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS17945 fccc9e79b7e5f7eba106d59d8b5fed06 171 ProSitePatterns PS01117 MarR-type HTH domain signature. 77 111 - T 10-11-2016 IPR023187 Transcriptional regulator MarR-type, conserved site A4G23_RS17945 fccc9e79b7e5f7eba106d59d8b5fed06 171 PRINTS PR00598 Bacterial regulatory protein MarR family signature 79 94 1.4E-7 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS17945 fccc9e79b7e5f7eba106d59d8b5fed06 171 PRINTS PR00598 Bacterial regulatory protein MarR family signature 62 78 1.4E-7 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS17945 fccc9e79b7e5f7eba106d59d8b5fed06 171 PRINTS PR00598 Bacterial regulatory protein MarR family signature 98 114 1.4E-7 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS17945 fccc9e79b7e5f7eba106d59d8b5fed06 171 PRINTS PR00598 Bacterial regulatory protein MarR family signature 128 148 1.4E-7 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS17945 fccc9e79b7e5f7eba106d59d8b5fed06 171 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 43 95 0.006 T 10-11-2016 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 A4G23_RS17945 fccc9e79b7e5f7eba106d59d8b5fed06 171 Gene3D G3DSA:1.10.10.10 7 152 2.0E-30 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS17945 fccc9e79b7e5f7eba106d59d8b5fed06 171 SMART SM00347 38 138 3.7E-15 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS05685 84f7bbd4cabfec38a39537e0ad32e377 329 Pfam PF02650 WhiA C-terminal HTH domain 221 303 1.6E-19 T 10-11-2016 IPR023054 Sporulation regulator WhiA, C-terminal A4G23_RS05685 84f7bbd4cabfec38a39537e0ad32e377 329 Pfam PF10298 WhiA N-terminal LAGLIDADG-like domain 20 104 7.8E-25 T 10-11-2016 IPR018478 Sporulation transcription regulator WhiA, N-terminal domain A4G23_RS05685 84f7bbd4cabfec38a39537e0ad32e377 329 TIGRFAM TIGR00647 DNA_bind_WhiA: DNA-binding protein WhiA 4 304 2.3E-110 T 10-11-2016 A4G23_RS05685 84f7bbd4cabfec38a39537e0ad32e377 329 Pfam PF14527 WhiA LAGLIDADG-like domain 127 218 1.0E-23 T 10-11-2016 A4G23_RS05685 84f7bbd4cabfec38a39537e0ad32e377 329 Hamap MF_01420 Putative sporulation transcription regulator WhiA [whiA]. 3 306 29.547 T 10-11-2016 IPR003802 Sporulation regulator WhiA GO:0043937 A4G23_RS26355 297ed62084a8d856c56587cc4264a76f 72 Pfam PF09360 Iron-binding zinc finger CDGSH type 22 67 7.2E-15 T 10-11-2016 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 A4G23_RS26355 297ed62084a8d856c56587cc4264a76f 72 SMART SM00704 28 72 5.4E-12 T 10-11-2016 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 A4G23_RS08145 78e83313ab23c808e6d7d072f8761464 368 Pfam PF05593 RHS Repeat 181 218 9.3E-6 T 10-11-2016 IPR031325 RHS repeat A4G23_RS08145 78e83313ab23c808e6d7d072f8761464 368 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 181 219 3.7E-7 T 10-11-2016 IPR006530 YD repeat A4G23_RS16320 3ac1f9a69bd5f907a6111aa87d35e103 340 Gene3D G3DSA:3.20.20.140 7 336 3.2E-83 T 10-11-2016 A4G23_RS16320 3ac1f9a69bd5f907a6111aa87d35e103 340 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 10 333 1.1E-115 T 10-11-2016 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 A4G23_RS16320 3ac1f9a69bd5f907a6111aa87d35e103 340 ProSitePatterns PS00485 Adenosine and AMP deaminase signature. 277 283 - T 10-11-2016 IPR006650 Adenosine/AMP deaminase active site GO:0009168|GO:0019239 Reactome: R-HSA-74217 A4G23_RS16320 3ac1f9a69bd5f907a6111aa87d35e103 340 Pfam PF00962 Adenosine/AMP deaminase 10 330 1.3E-94 T 10-11-2016 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 A4G23_RS16320 3ac1f9a69bd5f907a6111aa87d35e103 340 SUPERFAMILY SSF51556 7 336 9.68E-69 T 10-11-2016 IPR032466 Metal-dependent hydrolase A4G23_RS19695 cafb8b794f6312390c7171e921d62a12 158 Pfam PF12802 MarR family 40 100 1.3E-12 T 10-11-2016 A4G23_RS19695 cafb8b794f6312390c7171e921d62a12 158 SUPERFAMILY SSF46785 8 152 1.45E-28 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS19695 cafb8b794f6312390c7171e921d62a12 158 Gene3D G3DSA:1.10.10.10 4 152 1.9E-34 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS19695 cafb8b794f6312390c7171e921d62a12 158 SMART SM00347 34 137 7.1E-17 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS21005 fba4911443658bfee467c39c7f7ff5c2 250 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 130 147 - T 10-11-2016 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4G23_RS21005 fba4911443658bfee467c39c7f7ff5c2 250 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 5 108 7.3E-24 T 10-11-2016 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4G23_RS21005 fba4911443658bfee467c39c7f7ff5c2 250 Gene3D G3DSA:3.40.50.720 3 143 5.0E-49 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS21005 fba4911443658bfee467c39c7f7ff5c2 250 PIRSF PIRSF000161 2 250 5.3E-59 T 10-11-2016 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4G23_RS21005 fba4911443658bfee467c39c7f7ff5c2 250 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 4 248 28.875 T 10-11-2016 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4G23_RS21005 fba4911443658bfee467c39c7f7ff5c2 250 SUPERFAMILY SSF51735 4 135 2.43E-33 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS21005 fba4911443658bfee467c39c7f7ff5c2 250 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 44 248 1.2E-49 T 10-11-2016 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4G23_RS21005 fba4911443658bfee467c39c7f7ff5c2 250 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 111 247 1.4E-26 T 10-11-2016 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4G23_RS21005 fba4911443658bfee467c39c7f7ff5c2 250 SUPERFAMILY SSF55347 109 217 1.16E-37 T 10-11-2016 A4G23_RS21115 c2a19e4447d9110d7991220a58abd483 267 Gene3D G3DSA:1.10.8.50 124 262 7.7E-37 T 10-11-2016 A4G23_RS21115 c2a19e4447d9110d7991220a58abd483 267 SMART SM00898 2 110 5.5E-17 T 10-11-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 A4G23_RS21115 c2a19e4447d9110d7991220a58abd483 267 Gene3D G3DSA:3.20.190.10 2 97 1.0E-13 T 10-11-2016 A4G23_RS21115 c2a19e4447d9110d7991220a58abd483 267 SUPERFAMILY SSF46946 123 203 1.62E-19 T 10-11-2016 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 A4G23_RS21115 c2a19e4447d9110d7991220a58abd483 267 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 124 203 3.0E-10 T 10-11-2016 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 A4G23_RS21115 c2a19e4447d9110d7991220a58abd483 267 SUPERFAMILY SSF57716 217 261 1.28E-8 T 10-11-2016 A4G23_RS21115 c2a19e4447d9110d7991220a58abd483 267 SMART SM01232 124 214 6.9E-24 T 10-11-2016 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 A4G23_RS21115 c2a19e4447d9110d7991220a58abd483 267 ProSitePatterns PS01242 Zinc finger FPG-type signature. 233 261 - T 10-11-2016 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 A4G23_RS21115 c2a19e4447d9110d7991220a58abd483 267 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 75 1.0E-7 T 10-11-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 A4G23_RS21115 c2a19e4447d9110d7991220a58abd483 267 SUPERFAMILY SSF81624 2 125 8.11E-24 T 10-11-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 A4G23_RS08805 25d040427baf95ea9da249be489c7b23 530 Gene3D G3DSA:2.160.20.10 164 498 2.4E-71 T 10-11-2016 IPR012334 Pectin lyase fold A4G23_RS08805 25d040427baf95ea9da249be489c7b23 530 Gene3D G3DSA:2.60.120.260 37 159 1.0E-27 T 10-11-2016 IPR008979 Galactose-binding domain-like A4G23_RS08805 25d040427baf95ea9da249be489c7b23 530 SUPERFAMILY SSF49785 37 158 1.15E-25 T 10-11-2016 IPR008979 Galactose-binding domain-like A4G23_RS08805 25d040427baf95ea9da249be489c7b23 530 SUPERFAMILY SSF51126 166 498 1.73E-51 T 10-11-2016 IPR011050 Pectin lyase fold/virulence factor A4G23_RS08805 25d040427baf95ea9da249be489c7b23 530 Pfam PF13229 Right handed beta helix region 260 448 6.0E-10 T 10-11-2016 A4G23_RS08805 25d040427baf95ea9da249be489c7b23 530 Pfam PF03422 Carbohydrate binding module (family 6) 52 158 3.4E-11 T 10-11-2016 IPR005084 Carbohydrate binding module family 6 GO:0030246 A4G23_RS18595 6b824631d66edeee295c4ff3b38d22d6 426 SUPERFAMILY SSF158791 165 278 8.5E-32 T 10-11-2016 A4G23_RS18595 6b824631d66edeee295c4ff3b38d22d6 426 Pfam PF03448 MgtE intracellular N domain 178 278 1.5E-27 T 10-11-2016 IPR006668 Magnesium transporter, MgtE intracellular domain A4G23_RS18595 6b824631d66edeee295c4ff3b38d22d6 426 SMART SM00116 288 346 110.0 T 10-11-2016 IPR000644 CBS domain A4G23_RS18595 6b824631d66edeee295c4ff3b38d22d6 426 SMART SM00116 357 405 0.0046 T 10-11-2016 IPR000644 CBS domain A4G23_RS18595 6b824631d66edeee295c4ff3b38d22d6 426 SMART SM00924 178 281 1.1E-36 T 10-11-2016 IPR006668 Magnesium transporter, MgtE intracellular domain A4G23_RS18595 6b824631d66edeee295c4ff3b38d22d6 426 Gene3D G3DSA:1.25.60.10 163 276 1.7E-40 T 10-11-2016 A4G23_RS18595 6b824631d66edeee295c4ff3b38d22d6 426 SUPERFAMILY SSF50346 11 74 8.16E-6 T 10-11-2016 IPR011033 PRC-barrel-like A4G23_RS18595 6b824631d66edeee295c4ff3b38d22d6 426 SUPERFAMILY SSF54631 280 413 3.03E-24 T 10-11-2016 A4G23_RS18595 6b824631d66edeee295c4ff3b38d22d6 426 Pfam PF00571 CBS domain 350 405 1.1E-5 T 10-11-2016 IPR000644 CBS domain A4G23_RS18595 6b824631d66edeee295c4ff3b38d22d6 426 Pfam PF00571 CBS domain 282 342 0.0016 T 10-11-2016 IPR000644 CBS domain A4G23_RS18595 6b824631d66edeee295c4ff3b38d22d6 426 Gene3D G3DSA:3.10.580.10 279 405 2.6E-20 T 10-11-2016 A4G23_RS16210 df4a34720a6b030bdb78d994b74e16b3 257 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 37 179 9.5E-31 T 10-11-2016 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS11770 264760eedf9b71cb4d86564fc572e4c8 761 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 225 736 1.3E-82 T 10-11-2016 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A4G23_RS11770 264760eedf9b71cb4d86564fc572e4c8 761 Pfam PF00122 E1-E2 ATPase 224 442 2.0E-66 T 10-11-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 A4G23_RS11770 264760eedf9b71cb4d86564fc572e4c8 761 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 453 459 - T 10-11-2016 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 A4G23_RS11770 264760eedf9b71cb4d86564fc572e4c8 761 Gene3D G3DSA:3.40.50.1000 422 467 2.1E-49 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS11770 264760eedf9b71cb4d86564fc572e4c8 761 Gene3D G3DSA:3.40.50.1000 579 721 2.1E-49 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS11770 264760eedf9b71cb4d86564fc572e4c8 761 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 170 755 1.3E-180 T 10-11-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A4G23_RS11770 264760eedf9b71cb4d86564fc572e4c8 761 PRINTS PR00943 Copper-transporting ATPase signature 434 449 3.4E-8 T 10-11-2016 A4G23_RS11770 264760eedf9b71cb4d86564fc572e4c8 761 PRINTS PR00943 Copper-transporting ATPase signature 687 701 3.4E-8 T 10-11-2016 A4G23_RS11770 264760eedf9b71cb4d86564fc572e4c8 761 PRINTS PR00943 Copper-transporting ATPase signature 55 75 3.4E-8 T 10-11-2016 A4G23_RS11770 264760eedf9b71cb4d86564fc572e4c8 761 PRINTS PR00943 Copper-transporting ATPase signature 630 647 3.4E-8 T 10-11-2016 A4G23_RS11770 264760eedf9b71cb4d86564fc572e4c8 761 PRINTS PR00943 Copper-transporting ATPase signature 27 41 3.4E-8 T 10-11-2016 A4G23_RS11770 264760eedf9b71cb4d86564fc572e4c8 761 PRINTS PR00943 Copper-transporting ATPase signature 374 388 3.4E-8 T 10-11-2016 A4G23_RS11770 264760eedf9b71cb4d86564fc572e4c8 761 SUPERFAMILY SSF56784 449 469 1.06E-54 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS11770 264760eedf9b71cb4d86564fc572e4c8 761 SUPERFAMILY SSF56784 508 753 1.06E-54 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS11770 264760eedf9b71cb4d86564fc572e4c8 761 SUPERFAMILY SSF81653 256 351 2.88E-26 T 10-11-2016 A4G23_RS11770 264760eedf9b71cb4d86564fc572e4c8 761 Gene3D G3DSA:3.40.1110.10 468 578 3.6E-21 T 10-11-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A4G23_RS11770 264760eedf9b71cb4d86564fc572e4c8 761 Pfam PF00403 Heavy-metal-associated domain 15 74 3.6E-14 T 10-11-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A4G23_RS11770 264760eedf9b71cb4d86564fc572e4c8 761 SUPERFAMILY SSF81665 702 731 4.84E-13 T 10-11-2016 A4G23_RS11770 264760eedf9b71cb4d86564fc572e4c8 761 SUPERFAMILY SSF81665 352 445 4.84E-13 T 10-11-2016 A4G23_RS11770 264760eedf9b71cb4d86564fc572e4c8 761 SUPERFAMILY SSF81665 223 255 4.84E-13 T 10-11-2016 A4G23_RS11770 264760eedf9b71cb4d86564fc572e4c8 761 ProSitePatterns PS01047 Heavy-metal-associated domain. 17 45 - T 10-11-2016 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 A4G23_RS11770 264760eedf9b71cb4d86564fc572e4c8 761 Pfam PF00702 haloacid dehalogenase-like hydrolase 448 667 4.6E-44 T 10-11-2016 A4G23_RS11770 264760eedf9b71cb4d86564fc572e4c8 761 SUPERFAMILY SSF55008 7 78 8.38E-21 T 10-11-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A4G23_RS11770 264760eedf9b71cb4d86564fc572e4c8 761 Gene3D G3DSA:2.70.150.10 215 352 6.6E-31 T 10-11-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 A4G23_RS11770 264760eedf9b71cb4d86564fc572e4c8 761 Gene3D G3DSA:3.30.70.100 9 76 4.2E-24 T 10-11-2016 A4G23_RS11770 264760eedf9b71cb4d86564fc572e4c8 761 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 216 756 2.3E-153 T 10-11-2016 A4G23_RS11770 264760eedf9b71cb4d86564fc572e4c8 761 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 301 315 4.7E-23 T 10-11-2016 A4G23_RS11770 264760eedf9b71cb4d86564fc572e4c8 761 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 653 672 4.7E-23 T 10-11-2016 A4G23_RS11770 264760eedf9b71cb4d86564fc572e4c8 761 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 676 688 4.7E-23 T 10-11-2016 A4G23_RS11770 264760eedf9b71cb4d86564fc572e4c8 761 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 451 465 4.7E-23 T 10-11-2016 A4G23_RS11770 264760eedf9b71cb4d86564fc572e4c8 761 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 598 608 4.7E-23 T 10-11-2016 A4G23_RS24535 63b36ffaae84817eb4598b7aa4c02a47 415 Gene3D G3DSA:3.40.50.410 31 215 2.3E-13 T 10-11-2016 IPR002035 von Willebrand factor, type A A4G23_RS24535 63b36ffaae84817eb4598b7aa4c02a47 415 SMART SM00327 28 218 5.1E-19 T 10-11-2016 IPR002035 von Willebrand factor, type A A4G23_RS24535 63b36ffaae84817eb4598b7aa4c02a47 415 Pfam PF13519 von Willebrand factor type A domain 31 147 2.0E-11 T 10-11-2016 IPR002035 von Willebrand factor, type A A4G23_RS24535 63b36ffaae84817eb4598b7aa4c02a47 415 SUPERFAMILY SSF53300 29 215 1.93E-25 T 10-11-2016 IPR002035 von Willebrand factor, type A A4G23_RS19370 f88672c43c9a062a9ca5e6a2cd794e19 436 Pfam PF00672 HAMP domain 149 223 5.3E-11 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS19370 f88672c43c9a062a9ca5e6a2cd794e19 436 SUPERFAMILY SSF55874 275 423 3.8E-22 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS19370 f88672c43c9a062a9ca5e6a2cd794e19 436 SMART SM00304 168 227 2.5E-5 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS19370 f88672c43c9a062a9ca5e6a2cd794e19 436 Gene3D G3DSA:1.10.287.130 218 273 4.1E-12 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS19370 f88672c43c9a062a9ca5e6a2cd794e19 436 SUPERFAMILY SSF47384 214 286 2.55E-12 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS19370 f88672c43c9a062a9ca5e6a2cd794e19 436 Gene3D G3DSA:3.30.565.10 274 422 8.5E-20 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS19370 f88672c43c9a062a9ca5e6a2cd794e19 436 Pfam PF00512 His Kinase A (phospho-acceptor) domain 229 286 3.5E-12 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS19370 f88672c43c9a062a9ca5e6a2cd794e19 436 SMART SM00387 324 425 1.2E-18 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS19370 f88672c43c9a062a9ca5e6a2cd794e19 436 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 324 423 4.4E-10 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS19370 f88672c43c9a062a9ca5e6a2cd794e19 436 SMART SM00388 228 286 1.1E-13 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS19015 d90cab32cc910be4beeb5213ad55e421 336 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 125 330 1.1E-17 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS19015 d90cab32cc910be4beeb5213ad55e421 336 SUPERFAMILY SSF161098 93 320 1.83E-54 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS19015 d90cab32cc910be4beeb5213ad55e421 336 Gene3D G3DSA:1.10.3720.10 45 325 2.0E-57 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS09110 a0a056f8e569d5f2d15f7fa12172b72e 517 Gene3D G3DSA:3.40.50.1820 86 318 1.6E-56 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS09110 a0a056f8e569d5f2d15f7fa12172b72e 517 Gene3D G3DSA:3.40.50.1820 380 501 1.6E-56 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS09110 a0a056f8e569d5f2d15f7fa12172b72e 517 Pfam PF08386 TAP-like protein 409 512 1.5E-30 T 10-11-2016 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal A4G23_RS09110 a0a056f8e569d5f2d15f7fa12172b72e 517 SUPERFAMILY SSF53474 354 488 5.57E-24 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS09110 a0a056f8e569d5f2d15f7fa12172b72e 517 SUPERFAMILY SSF53474 121 250 5.57E-24 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS13460 4dc125c193d4c600b95b463c3e82f7a0 291 SMART SM01350 160 287 4.5E-6 T 10-11-2016 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A4G23_RS13460 4dc125c193d4c600b95b463c3e82f7a0 291 TIGRFAM TIGR00872 gnd_rel: 6-phosphogluconate dehydrogenase (decarboxylating) 1 291 1.1E-103 T 10-11-2016 IPR004849 6-phosphogluconate dehydrogenase, YqeC-type GO:0055114 A4G23_RS13460 4dc125c193d4c600b95b463c3e82f7a0 291 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 160 270 3.8E-26 T 10-11-2016 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A4G23_RS13460 4dc125c193d4c600b95b463c3e82f7a0 291 Gene3D G3DSA:1.10.1040.10 162 270 9.2E-36 T 10-11-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A4G23_RS13460 4dc125c193d4c600b95b463c3e82f7a0 291 SUPERFAMILY SSF48179 158 289 1.09E-41 T 10-11-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A4G23_RS13460 4dc125c193d4c600b95b463c3e82f7a0 291 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 50 79 7.6E-37 T 10-11-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A4G23_RS13460 4dc125c193d4c600b95b463c3e82f7a0 291 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 224 251 7.6E-37 T 10-11-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A4G23_RS13460 4dc125c193d4c600b95b463c3e82f7a0 291 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 149 177 7.6E-37 T 10-11-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A4G23_RS13460 4dc125c193d4c600b95b463c3e82f7a0 291 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 103 128 7.6E-37 T 10-11-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A4G23_RS13460 4dc125c193d4c600b95b463c3e82f7a0 291 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 1 15 7.6E-37 T 10-11-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A4G23_RS13460 4dc125c193d4c600b95b463c3e82f7a0 291 PIRSF PIRSF000103 1 288 4.9E-29 T 10-11-2016 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 A4G23_RS13460 4dc125c193d4c600b95b463c3e82f7a0 291 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 228 240 - T 10-11-2016 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A4G23_RS13460 4dc125c193d4c600b95b463c3e82f7a0 291 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 143 4.0E-38 T 10-11-2016 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 A4G23_RS13460 4dc125c193d4c600b95b463c3e82f7a0 291 SUPERFAMILY SSF51735 1 143 3.36E-46 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS13460 4dc125c193d4c600b95b463c3e82f7a0 291 Gene3D G3DSA:3.40.50.720 1 161 1.9E-48 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS17675 dfdee8ad75754f014eda39f3c9c05f87 242 SUPERFAMILY SSF88946 67 155 1.8E-16 T 10-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS17675 dfdee8ad75754f014eda39f3c9c05f87 242 SUPERFAMILY SSF88659 162 223 1.4E-16 T 10-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS17675 dfdee8ad75754f014eda39f3c9c05f87 242 Pfam PF04542 Sigma-70 region 2 81 143 2.5E-12 T 10-11-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS17675 dfdee8ad75754f014eda39f3c9c05f87 242 Pfam PF08281 Sigma-70, region 4 170 221 1.2E-14 T 10-11-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS17675 dfdee8ad75754f014eda39f3c9c05f87 242 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 74 223 3.0E-24 T 10-11-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS17675 dfdee8ad75754f014eda39f3c9c05f87 242 Gene3D G3DSA:1.10.10.10 164 223 6.0E-21 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS17675 dfdee8ad75754f014eda39f3c9c05f87 242 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 70 225 5.3E-62 T 10-11-2016 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 A4G23_RS17675 dfdee8ad75754f014eda39f3c9c05f87 242 Gene3D G3DSA:1.10.1740.10 69 143 1.7E-19 T 10-11-2016 A4G23_RS11075 6b3090adbbbbe481f51fbef733936e7e 904 Gene3D G3DSA:3.90.1150.10 353 452 5.1E-30 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS11075 6b3090adbbbbe481f51fbef733936e7e 904 Gene3D G3DSA:3.90.1150.10 22 78 5.1E-30 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS11075 6b3090adbbbbe481f51fbef733936e7e 904 Gene3D G3DSA:3.40.640.10 80 351 1.4E-80 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS11075 6b3090adbbbbe481f51fbef733936e7e 904 SUPERFAMILY SSF53383 43 451 1.21E-115 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS11075 6b3090adbbbbe481f51fbef733936e7e 904 Pfam PF00202 Aminotransferase class-III 44 449 1.3E-97 T 10-11-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4G23_RS11075 6b3090adbbbbe481f51fbef733936e7e 904 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 265 302 - T 10-11-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4G23_RS11075 6b3090adbbbbe481f51fbef733936e7e 904 SUPERFAMILY SSF56801 598 855 7.72E-20 T 10-11-2016 A4G23_RS11075 6b3090adbbbbe481f51fbef733936e7e 904 Pfam PF00501 AMP-binding enzyme 635 854 1.2E-8 T 10-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A4G23_RS16715 1e3e6af9cd2d63c591eddb8f3c262fe0 278 Hamap MF_01974 Methionine aminopeptidase [map]. 2 258 37.483 T 10-11-2016 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 A4G23_RS16715 1e3e6af9cd2d63c591eddb8f3c262fe0 278 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 173 191 - T 10-11-2016 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 A4G23_RS16715 1e3e6af9cd2d63c591eddb8f3c262fe0 278 PRINTS PR00599 Methionine aminopeptidase-1 signature 167 179 1.3E-21 T 10-11-2016 IPR001714 Peptidase M24, methionine aminopeptidase A4G23_RS16715 1e3e6af9cd2d63c591eddb8f3c262fe0 278 PRINTS PR00599 Methionine aminopeptidase-1 signature 67 80 1.3E-21 T 10-11-2016 IPR001714 Peptidase M24, methionine aminopeptidase A4G23_RS16715 1e3e6af9cd2d63c591eddb8f3c262fe0 278 PRINTS PR00599 Methionine aminopeptidase-1 signature 90 106 1.3E-21 T 10-11-2016 IPR001714 Peptidase M24, methionine aminopeptidase A4G23_RS16715 1e3e6af9cd2d63c591eddb8f3c262fe0 278 PRINTS PR00599 Methionine aminopeptidase-1 signature 200 212 1.3E-21 T 10-11-2016 IPR001714 Peptidase M24, methionine aminopeptidase A4G23_RS16715 1e3e6af9cd2d63c591eddb8f3c262fe0 278 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 3 257 2.6E-79 T 10-11-2016 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 A4G23_RS16715 1e3e6af9cd2d63c591eddb8f3c262fe0 278 Pfam PF00557 Metallopeptidase family M24 11 249 7.1E-43 T 10-11-2016 IPR000994 Peptidase M24, structural domain A4G23_RS16715 1e3e6af9cd2d63c591eddb8f3c262fe0 278 Gene3D G3DSA:3.90.230.10 3 259 1.6E-76 T 10-11-2016 IPR000994 Peptidase M24, structural domain A4G23_RS16715 1e3e6af9cd2d63c591eddb8f3c262fe0 278 SUPERFAMILY SSF55920 2 259 8.9E-74 T 10-11-2016 IPR000994 Peptidase M24, structural domain A4G23_RS15820 a87c3d9ad0184cbf1efc34f5e3af226f 435 SUPERFAMILY SSF53383 7 426 3.89E-116 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS15820 a87c3d9ad0184cbf1efc34f5e3af226f 435 Gene3D G3DSA:3.40.640.10 76 322 2.0E-76 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS15820 a87c3d9ad0184cbf1efc34f5e3af226f 435 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 9 430 96.72 T 10-11-2016 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 A4G23_RS15820 a87c3d9ad0184cbf1efc34f5e3af226f 435 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 10 423 1.0E-180 T 10-11-2016 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 A4G23_RS15820 a87c3d9ad0184cbf1efc34f5e3af226f 435 Pfam PF00202 Aminotransferase class-III 39 423 1.4E-79 T 10-11-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4G23_RS15820 a87c3d9ad0184cbf1efc34f5e3af226f 435 Gene3D G3DSA:3.90.1150.10 324 426 9.9E-38 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS15820 a87c3d9ad0184cbf1efc34f5e3af226f 435 Gene3D G3DSA:3.90.1150.10 3 75 9.9E-38 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS15820 a87c3d9ad0184cbf1efc34f5e3af226f 435 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 240 276 - T 10-11-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4G23_RS05700 f11c75854affde94a8aec170f7a70c30 695 Pfam PF02151 UvrB/uvrC motif 210 242 2.9E-10 T 10-11-2016 IPR001943 UVR domain GO:0005515 A4G23_RS05700 f11c75854affde94a8aec170f7a70c30 695 SMART SM00465 17 99 9.7E-21 T 10-11-2016 IPR000305 GIY-YIG nuclease superfamily A4G23_RS05700 f11c75854affde94a8aec170f7a70c30 695 SUPERFAMILY SSF47781 552 662 2.76E-21 T 10-11-2016 IPR010994 RuvA domain 2-like A4G23_RS05700 f11c75854affde94a8aec170f7a70c30 695 SUPERFAMILY SSF82771 17 101 2.22E-23 T 10-11-2016 IPR000305 GIY-YIG nuclease superfamily A4G23_RS05700 f11c75854affde94a8aec170f7a70c30 695 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 393 595 8.0E-51 T 10-11-2016 IPR001162 UvrC family homology region A4G23_RS05700 f11c75854affde94a8aec170f7a70c30 695 Pfam PF14520 Helix-hairpin-helix domain 611 661 1.3E-9 T 10-11-2016 A4G23_RS05700 f11c75854affde94a8aec170f7a70c30 695 SMART SM00278 609 628 96.0 T 10-11-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A4G23_RS05700 f11c75854affde94a8aec170f7a70c30 695 SMART SM00278 641 660 0.21 T 10-11-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A4G23_RS05700 f11c75854affde94a8aec170f7a70c30 695 Pfam PF01541 GIY-YIG catalytic domain 19 92 5.7E-11 T 10-11-2016 IPR000305 GIY-YIG nuclease superfamily A4G23_RS05700 f11c75854affde94a8aec170f7a70c30 695 Gene3D G3DSA:4.10.860.10 187 246 1.9E-18 T 10-11-2016 IPR001943 UVR domain GO:0005515 A4G23_RS05700 f11c75854affde94a8aec170f7a70c30 695 SUPERFAMILY SSF46600 194 246 2.88E-13 T 10-11-2016 IPR001943 UVR domain GO:0005515 A4G23_RS05700 f11c75854affde94a8aec170f7a70c30 695 Gene3D G3DSA:3.40.1440.10 18 95 1.1E-9 T 10-11-2016 IPR027299 GIY-YIG domain A4G23_RS05700 f11c75854affde94a8aec170f7a70c30 695 Gene3D G3DSA:1.10.150.20 609 658 6.2E-20 T 10-11-2016 A4G23_RS05700 f11c75854affde94a8aec170f7a70c30 695 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 11 476 4.6E-128 T 10-11-2016 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 A4G23_RS05700 f11c75854affde94a8aec170f7a70c30 695 Hamap MF_00203 UvrABC system protein C [uvrC]. 4 660 30.214 T 10-11-2016 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 A4G23_RS23935 57cd3d981f0079d7396a631de6e869e6 337 SUPERFAMILY SSF55347 126 255 4.09E-22 T 10-11-2016 A4G23_RS23935 57cd3d981f0079d7396a631de6e869e6 337 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 132 236 4.6E-8 T 10-11-2016 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 A4G23_RS23935 57cd3d981f0079d7396a631de6e869e6 337 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 1 115 2.8E-18 T 10-11-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 A4G23_RS23935 57cd3d981f0079d7396a631de6e869e6 337 Gene3D G3DSA:3.30.360.10 131 328 6.2E-48 T 10-11-2016 A4G23_RS23935 57cd3d981f0079d7396a631de6e869e6 337 Gene3D G3DSA:3.40.50.720 1 130 7.8E-34 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS23935 57cd3d981f0079d7396a631de6e869e6 337 SUPERFAMILY SSF51735 2 146 8.14E-38 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS26790 27f049cb94abb344e15aa29e476bf1cf 266 SUPERFAMILY SSF56752 21 245 6.02E-33 T 10-11-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 A4G23_RS26790 27f049cb94abb344e15aa29e476bf1cf 266 Gene3D G3DSA:3.30.470.10 24 63 1.2E-4 T 10-11-2016 A4G23_RS26790 27f049cb94abb344e15aa29e476bf1cf 266 Gene3D G3DSA:3.20.10.10 123 243 5.0E-15 T 10-11-2016 A4G23_RS26790 27f049cb94abb344e15aa29e476bf1cf 266 Pfam PF01063 Amino-transferase class IV 27 239 8.4E-32 T 10-11-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 A4G23_RS24710 9e78dfb83e798f126dfbbcbd3689168e 539 SUPERFAMILY SSF52540 22 224 1.61E-43 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS24710 9e78dfb83e798f126dfbbcbd3689168e 539 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS24710 9e78dfb83e798f126dfbbcbd3689168e 539 Pfam PF00005 ABC transporter 27 175 1.2E-21 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS24710 9e78dfb83e798f126dfbbcbd3689168e 539 Pfam PF00005 ABC transporter 362 487 3.0E-19 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS24710 9e78dfb83e798f126dfbbcbd3689168e 539 Gene3D G3DSA:3.40.50.300 12 255 2.8E-46 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS24710 9e78dfb83e798f126dfbbcbd3689168e 539 Gene3D G3DSA:3.40.50.300 362 518 7.0E-30 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS24710 9e78dfb83e798f126dfbbcbd3689168e 539 SMART SM00382 34 219 1.8E-12 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS24710 9e78dfb83e798f126dfbbcbd3689168e 539 SMART SM00382 366 533 1.9E-13 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS24710 9e78dfb83e798f126dfbbcbd3689168e 539 SUPERFAMILY SSF52540 362 529 2.1E-33 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS11985 ee596676c239fdc43e29f6af102d9eb3 540 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 522 2.7E-98 T 10-11-2016 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 A4G23_RS11985 ee596676c239fdc43e29f6af102d9eb3 540 Hamap MF_00600 60 kDa chaperonin [groL]. 1 538 41.642 T 10-11-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 A4G23_RS11985 ee596676c239fdc43e29f6af102d9eb3 540 Gene3D G3DSA:3.50.7.10 195 368 5.9E-93 T 10-11-2016 IPR027409 GroEL-like apical domain A4G23_RS11985 ee596676c239fdc43e29f6af102d9eb3 540 SUPERFAMILY SSF48592 6 133 8.33E-76 T 10-11-2016 A4G23_RS11985 ee596676c239fdc43e29f6af102d9eb3 540 SUPERFAMILY SSF48592 404 518 8.33E-76 T 10-11-2016 A4G23_RS11985 ee596676c239fdc43e29f6af102d9eb3 540 Gene3D G3DSA:1.10.560.10 369 515 3.1E-40 T 10-11-2016 IPR027413 GroEL-like equatorial domain A4G23_RS11985 ee596676c239fdc43e29f6af102d9eb3 540 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 524 2.1E-250 T 10-11-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 A4G23_RS11985 ee596676c239fdc43e29f6af102d9eb3 540 Gene3D G3DSA:1.10.560.10 6 194 8.1E-48 T 10-11-2016 IPR027413 GroEL-like equatorial domain A4G23_RS11985 ee596676c239fdc43e29f6af102d9eb3 540 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 10-11-2016 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020 A4G23_RS11985 ee596676c239fdc43e29f6af102d9eb3 540 PRINTS PR00298 60kDa chaperonin signature 348 373 3.8E-70 T 10-11-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 A4G23_RS11985 ee596676c239fdc43e29f6af102d9eb3 540 PRINTS PR00298 60kDa chaperonin signature 26 52 3.8E-70 T 10-11-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 A4G23_RS11985 ee596676c239fdc43e29f6af102d9eb3 540 PRINTS PR00298 60kDa chaperonin signature 396 417 3.8E-70 T 10-11-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 A4G23_RS11985 ee596676c239fdc43e29f6af102d9eb3 540 PRINTS PR00298 60kDa chaperonin signature 266 289 3.8E-70 T 10-11-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 A4G23_RS11985 ee596676c239fdc43e29f6af102d9eb3 540 PRINTS PR00298 60kDa chaperonin signature 82 109 3.8E-70 T 10-11-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 A4G23_RS11985 ee596676c239fdc43e29f6af102d9eb3 540 SUPERFAMILY SSF52029 184 374 7.48E-83 T 10-11-2016 IPR027409 GroEL-like apical domain A4G23_RS11985 ee596676c239fdc43e29f6af102d9eb3 540 SUPERFAMILY SSF54849 137 202 6.18E-27 T 10-11-2016 A4G23_RS05870 af978d61f6e2ee01dc6e18dee7f2c8e0 162 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 36 146 9.1E-29 T 10-11-2016 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-75105 A4G23_RS05870 af978d61f6e2ee01dc6e18dee7f2c8e0 162 Gene3D G3DSA:3.10.129.10 23 148 1.0E-45 T 10-11-2016 IPR029069 HotDog domain A4G23_RS05870 af978d61f6e2ee01dc6e18dee7f2c8e0 162 Pfam PF03061 Thioesterase superfamily 62 139 5.9E-18 T 10-11-2016 IPR006683 Thioesterase domain Reactome: R-HSA-75105 A4G23_RS05870 af978d61f6e2ee01dc6e18dee7f2c8e0 162 SUPERFAMILY SSF54637 29 150 7.29E-28 T 10-11-2016 IPR029069 HotDog domain A4G23_RS26675 6355898f35eb9c631d3ae39d188f577d 140 SUPERFAMILY SSF46785 23 136 6.13E-34 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS26675 6355898f35eb9c631d3ae39d188f577d 140 Gene3D G3DSA:1.10.10.10 21 131 7.1E-44 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS26675 6355898f35eb9c631d3ae39d188f577d 140 Pfam PF01638 HxlR-like helix-turn-helix 35 118 2.1E-27 T 10-11-2016 IPR002577 Helix-turn-helix, HxlR type A4G23_RS20355 c87561f44fe46d165f0ed576f6ce0822 336 SUPERFAMILY SSF48179 182 334 2.61E-54 T 10-11-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A4G23_RS20355 c87561f44fe46d165f0ed576f6ce0822 336 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 183 321 2.4E-47 T 10-11-2016 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 A4G23_RS20355 c87561f44fe46d165f0ed576f6ce0822 336 Gene3D G3DSA:3.40.50.720 3 186 1.9E-64 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS20355 c87561f44fe46d165f0ed576f6ce0822 336 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 7 162 5.1E-48 T 10-11-2016 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 A4G23_RS20355 c87561f44fe46d165f0ed576f6ce0822 336 SUPERFAMILY SSF51735 4 183 5.52E-53 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS20355 c87561f44fe46d165f0ed576f6ce0822 336 PIRSF PIRSF000114 2 335 5.9E-97 T 10-11-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 A4G23_RS20355 c87561f44fe46d165f0ed576f6ce0822 336 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 5 325 37.437 T 10-11-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 A4G23_RS20355 c87561f44fe46d165f0ed576f6ce0822 336 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 241 258 5.1E-43 T 10-11-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 A4G23_RS20355 c87561f44fe46d165f0ed576f6ce0822 336 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 136 156 5.1E-43 T 10-11-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 A4G23_RS20355 c87561f44fe46d165f0ed576f6ce0822 336 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 59 86 5.1E-43 T 10-11-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 A4G23_RS20355 c87561f44fe46d165f0ed576f6ce0822 336 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 9 26 5.1E-43 T 10-11-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 A4G23_RS20355 c87561f44fe46d165f0ed576f6ce0822 336 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 176 200 5.1E-43 T 10-11-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 A4G23_RS20355 c87561f44fe46d165f0ed576f6ce0822 336 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 201 225 5.1E-43 T 10-11-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 A4G23_RS20355 c87561f44fe46d165f0ed576f6ce0822 336 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 191 212 - T 10-11-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 A4G23_RS20355 c87561f44fe46d165f0ed576f6ce0822 336 Gene3D G3DSA:1.10.1040.10 187 329 9.2E-53 T 10-11-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A4G23_RS03550 12f32ef76d94799b2cc8bd9b006b6531 379 PRINTS PR00097 Anthranilate synthase component II signature 349 362 1.8E-5 T 10-11-2016 A4G23_RS03550 12f32ef76d94799b2cc8bd9b006b6531 379 PRINTS PR00097 Anthranilate synthase component II signature 230 239 1.8E-5 T 10-11-2016 A4G23_RS03550 12f32ef76d94799b2cc8bd9b006b6531 379 PRINTS PR00097 Anthranilate synthase component II signature 258 269 1.8E-5 T 10-11-2016 A4G23_RS03550 12f32ef76d94799b2cc8bd9b006b6531 379 SUPERFAMILY SSF52317 156 375 2.96E-50 T 10-11-2016 IPR029062 Class I glutamine amidotransferase-like A4G23_RS03550 12f32ef76d94799b2cc8bd9b006b6531 379 SUPERFAMILY SSF52021 11 145 5.49E-56 T 10-11-2016 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 A4G23_RS03550 12f32ef76d94799b2cc8bd9b006b6531 379 Gene3D G3DSA:3.50.30.20 11 148 2.1E-59 T 10-11-2016 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 A4G23_RS03550 12f32ef76d94799b2cc8bd9b006b6531 379 SMART SM01097 10 140 2.5E-87 T 10-11-2016 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 A4G23_RS03550 12f32ef76d94799b2cc8bd9b006b6531 379 Gene3D G3DSA:3.40.50.880 161 376 3.2E-62 T 10-11-2016 IPR029062 Class I glutamine amidotransferase-like A4G23_RS03550 12f32ef76d94799b2cc8bd9b006b6531 379 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 227 241 3.7E-30 T 10-11-2016 A4G23_RS03550 12f32ef76d94799b2cc8bd9b006b6531 379 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 275 292 3.7E-30 T 10-11-2016 A4G23_RS03550 12f32ef76d94799b2cc8bd9b006b6531 379 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 258 274 3.7E-30 T 10-11-2016 A4G23_RS03550 12f32ef76d94799b2cc8bd9b006b6531 379 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 300 311 3.7E-30 T 10-11-2016 A4G23_RS03550 12f32ef76d94799b2cc8bd9b006b6531 379 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 188 202 3.7E-30 T 10-11-2016 A4G23_RS03550 12f32ef76d94799b2cc8bd9b006b6531 379 Pfam PF00117 Glutamine amidotransferase class-I 192 372 2.8E-37 T 10-11-2016 IPR017926 Glutamine amidotransferase A4G23_RS03550 12f32ef76d94799b2cc8bd9b006b6531 379 PRINTS PR00096 Glutamine amidotransferase superfamily signature 349 362 8.0E-11 T 10-11-2016 A4G23_RS03550 12f32ef76d94799b2cc8bd9b006b6531 379 PRINTS PR00096 Glutamine amidotransferase superfamily signature 258 269 8.0E-11 T 10-11-2016 A4G23_RS03550 12f32ef76d94799b2cc8bd9b006b6531 379 PRINTS PR00096 Glutamine amidotransferase superfamily signature 230 239 8.0E-11 T 10-11-2016 A4G23_RS03550 12f32ef76d94799b2cc8bd9b006b6531 379 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 12 138 1.8E-52 T 10-11-2016 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 A4G23_RS03550 12f32ef76d94799b2cc8bd9b006b6531 379 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 12 375 3.2E-137 T 10-11-2016 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 A4G23_RS03550 12f32ef76d94799b2cc8bd9b006b6531 379 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 10 378 46.466 T 10-11-2016 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 A4G23_RS11280 b6bcff45d5f9ae14cf593aa16dd2cf25 342 Gene3D G3DSA:3.40.50.300 9 236 2.0E-67 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS11280 b6bcff45d5f9ae14cf593aa16dd2cf25 342 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 21 323 8.3E-111 T 10-11-2016 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 A4G23_RS11280 b6bcff45d5f9ae14cf593aa16dd2cf25 342 SMART SM00382 38 221 1.4E-11 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS11280 b6bcff45d5f9ae14cf593aa16dd2cf25 342 SUPERFAMILY SSF52540 12 235 4.6E-57 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS11280 b6bcff45d5f9ae14cf593aa16dd2cf25 342 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS11280 b6bcff45d5f9ae14cf593aa16dd2cf25 342 Pfam PF00005 ABC transporter 30 172 1.1E-27 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS15500 6dbee1c3bf620168c14e2135e73f4559 309 Gene3D G3DSA:3.30.420.40 1 123 3.5E-33 T 10-11-2016 A4G23_RS15500 6dbee1c3bf620168c14e2135e73f4559 309 SUPERFAMILY SSF53067 2 125 4.23E-29 T 10-11-2016 A4G23_RS15500 6dbee1c3bf620168c14e2135e73f4559 309 SUPERFAMILY SSF53067 129 306 4.75E-36 T 10-11-2016 A4G23_RS15500 6dbee1c3bf620168c14e2135e73f4559 309 Pfam PF02541 Ppx/GppA phosphatase family 29 305 3.9E-68 T 10-11-2016 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 A4G23_RS15500 6dbee1c3bf620168c14e2135e73f4559 309 Gene3D G3DSA:3.30.420.150 125 305 7.8E-47 T 10-11-2016 A4G23_RS11070 d0c33b0d06cf52d3c452160aacc7ea88 477 Gene3D G3DSA:3.40.605.10 22 290 4.7E-11 T 10-11-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A4G23_RS11070 d0c33b0d06cf52d3c452160aacc7ea88 477 SUPERFAMILY SSF53720 16 461 1.07E-28 T 10-11-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A4G23_RS11070 d0c33b0d06cf52d3c452160aacc7ea88 477 Pfam PF00171 Aldehyde dehydrogenase family 177 412 2.4E-15 T 10-11-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A4G23_RS11070 d0c33b0d06cf52d3c452160aacc7ea88 477 Gene3D G3DSA:3.40.309.10 291 432 3.8E-8 T 10-11-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 A4G23_RS09410 424e3693a98370103dcae6cb59da5188 200 Gene3D G3DSA:3.90.950.10 1 198 5.9E-80 T 10-11-2016 IPR029001 Inosine triphosphate pyrophosphatase-like A4G23_RS09410 424e3693a98370103dcae6cb59da5188 200 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 2 197 47.115 T 10-11-2016 IPR020922 Non-canonical purine NTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 A4G23_RS09410 424e3693a98370103dcae6cb59da5188 200 Pfam PF01725 Ham1 family 4 192 3.9E-54 T 10-11-2016 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206|Reactome: R-HSA-15869 A4G23_RS09410 424e3693a98370103dcae6cb59da5188 200 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 4 192 6.1E-52 T 10-11-2016 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206|Reactome: R-HSA-15869 A4G23_RS09410 424e3693a98370103dcae6cb59da5188 200 SUPERFAMILY SSF52972 1 196 1.07E-65 T 10-11-2016 IPR029001 Inosine triphosphate pyrophosphatase-like A4G23_RS18530 77f3934d08ab24cca0ccb0c759f44f89 286 SUPERFAMILY SSF51717 4 275 6.28E-82 T 10-11-2016 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4G23_RS18530 77f3934d08ab24cca0ccb0c759f44f89 286 Gene3D G3DSA:3.20.20.20 12 274 3.3E-85 T 10-11-2016 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4G23_RS18530 77f3934d08ab24cca0ccb0c759f44f89 286 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 50 63 - T 10-11-2016 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4G23_RS18530 77f3934d08ab24cca0ccb0c759f44f89 286 Pfam PF00809 Pterin binding enzyme 17 257 1.5E-64 T 10-11-2016 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4G23_RS18530 77f3934d08ab24cca0ccb0c759f44f89 286 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 16 271 1.1E-80 T 10-11-2016 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 A4G23_RS18530 77f3934d08ab24cca0ccb0c759f44f89 286 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 16 31 - T 10-11-2016 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4G23_RS08935 5129e8ec3c1eea3316b2a268dc2cd1fa 293 Gene3D G3DSA:3.10.129.10 5 118 4.1E-45 T 10-11-2016 IPR029069 HotDog domain A4G23_RS08935 5129e8ec3c1eea3316b2a268dc2cd1fa 293 Pfam PF13622 Thioesterase-like superfamily 33 289 1.6E-60 T 10-11-2016 A4G23_RS08935 5129e8ec3c1eea3316b2a268dc2cd1fa 293 SUPERFAMILY SSF54637 5 117 1.95E-39 T 10-11-2016 IPR029069 HotDog domain A4G23_RS08935 5129e8ec3c1eea3316b2a268dc2cd1fa 293 Gene3D G3DSA:3.10.129.10 127 292 1.2E-54 T 10-11-2016 IPR029069 HotDog domain A4G23_RS08935 5129e8ec3c1eea3316b2a268dc2cd1fa 293 SUPERFAMILY SSF54637 119 292 6.93E-50 T 10-11-2016 IPR029069 HotDog domain A4G23_RS19365 98006dfe6d7fbf8ab8bedc78fee19223 443 Pfam PF01098 Cell cycle protein 81 438 4.5E-71 T 10-11-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 A4G23_RS17165 8f3f01b94b6c4fae71abe509cce04b0e 176 Pfam PF00293 NUDIX domain 47 153 1.5E-17 T 10-11-2016 IPR000086 NUDIX hydrolase domain GO:0016787 A4G23_RS17165 8f3f01b94b6c4fae71abe509cce04b0e 176 Gene3D G3DSA:3.90.79.10 7 170 1.1E-35 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS17165 8f3f01b94b6c4fae71abe509cce04b0e 176 PRINTS PR00502 NUDIX hydrolase family signature 69 83 6.6E-6 T 10-11-2016 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A4G23_RS17165 8f3f01b94b6c4fae71abe509cce04b0e 176 PRINTS PR00502 NUDIX hydrolase family signature 83 98 6.6E-6 T 10-11-2016 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A4G23_RS17165 8f3f01b94b6c4fae71abe509cce04b0e 176 ProSitePatterns PS00893 Nudix box signature. 74 95 - T 10-11-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A4G23_RS17165 8f3f01b94b6c4fae71abe509cce04b0e 176 SUPERFAMILY SSF55811 3 171 3.52E-36 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS02520 69de099a20201281fe98baf42fb160fa 389 Pfam PF05147 Lanthionine synthetase C-like protein 129 341 5.3E-16 T 10-11-2016 IPR007822 Lanthionine synthetase C-like A4G23_RS02520 69de099a20201281fe98baf42fb160fa 389 PRINTS PR01950 LanC-like protein superfamily signature 264 284 1.4E-7 T 10-11-2016 IPR007822 Lanthionine synthetase C-like A4G23_RS02520 69de099a20201281fe98baf42fb160fa 389 PRINTS PR01950 LanC-like protein superfamily signature 197 213 1.4E-7 T 10-11-2016 IPR007822 Lanthionine synthetase C-like A4G23_RS02520 69de099a20201281fe98baf42fb160fa 389 PRINTS PR01950 LanC-like protein superfamily signature 135 150 1.4E-7 T 10-11-2016 IPR007822 Lanthionine synthetase C-like A4G23_RS02520 69de099a20201281fe98baf42fb160fa 389 SUPERFAMILY SSF158745 89 342 1.57E-24 T 10-11-2016 A4G23_RS02520 69de099a20201281fe98baf42fb160fa 389 SMART SM01260 36 389 1.2E-5 T 10-11-2016 IPR007822 Lanthionine synthetase C-like A4G23_RS23195 5f4f525dadeace0648baca8e74d43ef6 565 SUPERFAMILY SSF56014 173 333 1.22E-45 T 10-11-2016 A4G23_RS23195 5f4f525dadeace0648baca8e74d43ef6 565 Gene3D G3DSA:3.90.480.10 342 417 1.2E-49 T 10-11-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4G23_RS23195 5f4f525dadeace0648baca8e74d43ef6 565 Gene3D G3DSA:3.90.480.10 102 170 1.2E-49 T 10-11-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4G23_RS23195 5f4f525dadeace0648baca8e74d43ef6 565 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 102 164 1.4E-20 T 10-11-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4G23_RS23195 5f4f525dadeace0648baca8e74d43ef6 565 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 349 414 1.4E-15 T 10-11-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4G23_RS23195 5f4f525dadeace0648baca8e74d43ef6 565 SUPERFAMILY SSF56014 422 563 4.45E-36 T 10-11-2016 A4G23_RS23195 5f4f525dadeace0648baca8e74d43ef6 565 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 173 326 3.3E-40 T 10-11-2016 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4G23_RS23195 5f4f525dadeace0648baca8e74d43ef6 565 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 426 562 5.0E-10 T 10-11-2016 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4G23_RS23195 5f4f525dadeace0648baca8e74d43ef6 565 PRINTS PR00397 Sirohaem Fe-binding site signature 471 489 1.4E-9 T 10-11-2016 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4G23_RS23195 5f4f525dadeace0648baca8e74d43ef6 565 PRINTS PR00397 Sirohaem Fe-binding site signature 426 444 1.4E-9 T 10-11-2016 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4G23_RS23195 5f4f525dadeace0648baca8e74d43ef6 565 Gene3D G3DSA:3.30.413.10 423 563 6.2E-37 T 10-11-2016 A4G23_RS23195 5f4f525dadeace0648baca8e74d43ef6 565 SUPERFAMILY SSF55124 22 172 3.34E-39 T 10-11-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4G23_RS23195 5f4f525dadeace0648baca8e74d43ef6 565 Gene3D G3DSA:3.30.413.10 173 325 2.0E-43 T 10-11-2016 A4G23_RS23195 5f4f525dadeace0648baca8e74d43ef6 565 SUPERFAMILY SSF55124 305 437 1.12E-20 T 10-11-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4G23_RS23195 5f4f525dadeace0648baca8e74d43ef6 565 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 471 487 - T 10-11-2016 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4G23_RS12815 82bc01bac87f95661c91cb88de01bb5d 219 Gene3D G3DSA:3.90.50.10 14 103 2.8E-5 T 10-11-2016 IPR014747 Bacterial photosynthetic reaction centre, H-chain, C-terminal GO:0019684|GO:0030077|GO:0045156 A4G23_RS12815 82bc01bac87f95661c91cb88de01bb5d 219 Pfam PF05239 PRC-barrel domain 12 78 1.3E-8 T 10-11-2016 IPR027275 PRC-barrel domain A4G23_RS12815 82bc01bac87f95661c91cb88de01bb5d 219 Pfam PF09557 Domain of unknown function (DUF2382) 150 202 4.7E-8 T 10-11-2016 IPR019060 Domain of unknown function DUF2382 A4G23_RS12815 82bc01bac87f95661c91cb88de01bb5d 219 SUPERFAMILY SSF50346 8 114 1.73E-20 T 10-11-2016 IPR011033 PRC-barrel-like A4G23_RS15630 4d6b91b5abf2482315f1a1232633c281 330 Gene3D G3DSA:3.40.190.10 115 212 8.5E-28 T 10-11-2016 A4G23_RS15630 4d6b91b5abf2482315f1a1232633c281 330 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 12 223 3.0E-63 T 10-11-2016 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4G23_RS15630 4d6b91b5abf2482315f1a1232633c281 330 PIRSF PIRSF001438 1 330 2.9E-103 T 10-11-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4G23_RS15630 4d6b91b5abf2482315f1a1232633c281 330 PRINTS PR00151 Porphobilinogen deaminase signature 49 69 7.1E-16 T 10-11-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4G23_RS15630 4d6b91b5abf2482315f1a1232633c281 330 PRINTS PR00151 Porphobilinogen deaminase signature 80 99 7.1E-16 T 10-11-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4G23_RS15630 4d6b91b5abf2482315f1a1232633c281 330 PRINTS PR00151 Porphobilinogen deaminase signature 133 150 7.1E-16 T 10-11-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4G23_RS15630 4d6b91b5abf2482315f1a1232633c281 330 PRINTS PR00151 Porphobilinogen deaminase signature 243 260 7.1E-16 T 10-11-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4G23_RS15630 4d6b91b5abf2482315f1a1232633c281 330 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 12 319 6.3E-79 T 10-11-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4G23_RS15630 4d6b91b5abf2482315f1a1232633c281 330 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 240 317 7.2E-18 T 10-11-2016 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4G23_RS15630 4d6b91b5abf2482315f1a1232633c281 330 SUPERFAMILY SSF54782 233 327 3.4E-19 T 10-11-2016 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4G23_RS15630 4d6b91b5abf2482315f1a1232633c281 330 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 11 319 32.82 T 10-11-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4G23_RS15630 4d6b91b5abf2482315f1a1232633c281 330 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 244 260 - T 10-11-2016 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4G23_RS15630 4d6b91b5abf2482315f1a1232633c281 330 Gene3D G3DSA:3.40.190.10 9 114 2.9E-36 T 10-11-2016 A4G23_RS15630 4d6b91b5abf2482315f1a1232633c281 330 Gene3D G3DSA:3.30.160.40 234 326 2.1E-23 T 10-11-2016 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4G23_RS15630 4d6b91b5abf2482315f1a1232633c281 330 SUPERFAMILY SSF53850 10 231 3.04E-58 T 10-11-2016 A4G23_RS23055 b4f28433fd5003d72d9dd613b5423997 214 SUPERFAMILY SSF52540 26 212 2.76E-29 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS23055 b4f28433fd5003d72d9dd613b5423997 214 SMART SM00382 27 164 0.0032 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS23055 b4f28433fd5003d72d9dd613b5423997 214 Gene3D G3DSA:3.40.50.300 13 212 1.6E-53 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS23055 b4f28433fd5003d72d9dd613b5423997 214 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 31 213 3.0E-8 T 10-11-2016 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 A4G23_RS17355 83d7e253c73399cab0f12d42dcbca436 255 SUPERFAMILY SSF48498 87 227 2.09E-46 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS17355 83d7e253c73399cab0f12d42dcbca436 255 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 2.2E-11 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS17355 83d7e253c73399cab0f12d42dcbca436 255 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 2.2E-11 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS17355 83d7e253c73399cab0f12d42dcbca436 255 Gene3D G3DSA:1.10.357.10 12 203 1.2E-36 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS17355 83d7e253c73399cab0f12d42dcbca436 255 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 64 1.2E-18 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS17355 83d7e253c73399cab0f12d42dcbca436 255 SUPERFAMILY SSF46689 9 90 3.99E-21 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS17355 83d7e253c73399cab0f12d42dcbca436 255 ProSitePatterns PS01081 TetR-type HTH domain signature. 32 63 - T 10-11-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A4G23_RS14835 8e60bc188df4dbf72d387091c1b949cf 296 Pfam PF01145 SPFH domain / Band 7 family 50 232 1.5E-24 T 10-11-2016 IPR001107 Band 7 domain A4G23_RS14835 8e60bc188df4dbf72d387091c1b949cf 296 SUPERFAMILY SSF117892 79 217 3.92E-13 T 10-11-2016 IPR001107 Band 7 domain A4G23_RS14835 8e60bc188df4dbf72d387091c1b949cf 296 SMART SM00244 46 212 5.5E-10 T 10-11-2016 IPR001107 Band 7 domain A4G23_RS26740 73eaae5f3f72c0660a13ce1e0c7a20da 413 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 8 409 1.4E-100 T 10-11-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 A4G23_RS26740 73eaae5f3f72c0660a13ce1e0c7a20da 413 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 11 412 1.9E-114 T 10-11-2016 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 A4G23_RS26740 73eaae5f3f72c0660a13ce1e0c7a20da 413 SUPERFAMILY SSF55205 4 412 1.15E-102 T 10-11-2016 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 A4G23_RS26740 73eaae5f3f72c0660a13ce1e0c7a20da 413 Gene3D G3DSA:3.65.10.10 16 226 9.5E-61 T 10-11-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 A4G23_RS26740 73eaae5f3f72c0660a13ce1e0c7a20da 413 Gene3D G3DSA:3.65.10.10 227 409 1.6E-56 T 10-11-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 A4G23_RS26740 73eaae5f3f72c0660a13ce1e0c7a20da 413 ProSitePatterns PS00885 EPSP synthase signature 2. 327 345 - T 10-11-2016 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 A4G23_RS26740 73eaae5f3f72c0660a13ce1e0c7a20da 413 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 4 413 28.387 T 10-11-2016 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 A4G23_RS26740 73eaae5f3f72c0660a13ce1e0c7a20da 413 PIRSF PIRSF000505 2 413 1.4E-127 T 10-11-2016 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 A4G23_RS20400 4dff11d881f58b553c55ae438704c18b 169 Pfam PF01467 Cytidylyltransferase-like 16 142 4.9E-19 T 10-11-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A4G23_RS20400 4dff11d881f58b553c55ae438704c18b 169 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 12 30 1.1E-46 T 10-11-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 A4G23_RS20400 4dff11d881f58b553c55ae438704c18b 169 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 121 143 1.1E-46 T 10-11-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 A4G23_RS20400 4dff11d881f58b553c55ae438704c18b 169 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 30 51 1.1E-46 T 10-11-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 A4G23_RS20400 4dff11d881f58b553c55ae438704c18b 169 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 59 83 1.1E-46 T 10-11-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 A4G23_RS20400 4dff11d881f58b553c55ae438704c18b 169 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 95 111 1.1E-46 T 10-11-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 A4G23_RS20400 4dff11d881f58b553c55ae438704c18b 169 ProDom PD016147 LIGASE LYASE CITRATE PRO-3S-LYASE SYNTHETASE TRANSFERASE CYTIDYLTRANSFERASE-RELATED:CITRATE ACETATE:SH-CITRATE CITC PLASMID 21 76 6.0E-4 T 10-11-2016 A4G23_RS20400 4dff11d881f58b553c55ae438704c18b 169 SUPERFAMILY SSF52374 12 163 2.68E-44 T 10-11-2016 A4G23_RS20400 4dff11d881f58b553c55ae438704c18b 169 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 13 164 4.1E-57 T 10-11-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 A4G23_RS20400 4dff11d881f58b553c55ae438704c18b 169 Gene3D G3DSA:3.40.50.620 12 164 2.0E-50 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS20400 4dff11d881f58b553c55ae438704c18b 169 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 13 70 6.8E-15 T 10-11-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A4G23_RS20400 4dff11d881f58b553c55ae438704c18b 169 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 12 167 33.781 T 10-11-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 A4G23_RS18195 939014b46cfdea6bc373bf57ff4fe6a1 179 SUPERFAMILY SSF69118 3 172 3.66E-49 T 10-11-2016 IPR029032 AhpD-like Reactome: R-HSA-5628897 A4G23_RS18195 939014b46cfdea6bc373bf57ff4fe6a1 179 Pfam PF02627 Carboxymuconolactone decarboxylase family 94 175 8.4E-17 T 10-11-2016 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A4G23_RS18195 939014b46cfdea6bc373bf57ff4fe6a1 179 Hamap MF_01676 Alkyl hydroperoxide reductase AhpD [ahpD]. 1 179 86.778 T 10-11-2016 IPR004674 Alkylhydroperoxidase AhpD GO:0006979|GO:0032843|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A4G23_RS18195 939014b46cfdea6bc373bf57ff4fe6a1 179 TIGRFAM TIGR00777 ahpD: alkylhydroperoxidase, AhpD family 2 177 6.4E-94 T 10-11-2016 IPR004674 Alkylhydroperoxidase AhpD GO:0006979|GO:0032843|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A4G23_RS18195 939014b46cfdea6bc373bf57ff4fe6a1 179 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 112 160 1.1E-19 T 10-11-2016 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A4G23_RS18195 939014b46cfdea6bc373bf57ff4fe6a1 179 Gene3D G3DSA:1.20.1290.10 1 172 1.8E-58 T 10-11-2016 IPR029032 AhpD-like Reactome: R-HSA-5628897 A4G23_RS23520 e62f14f2d9cc6e7e4741188e59a34a92 695 Pfam PF01032 FecCD transport family 383 690 3.4E-82 T 10-11-2016 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 A4G23_RS23520 e62f14f2d9cc6e7e4741188e59a34a92 695 Pfam PF01032 FecCD transport family 41 349 1.5E-80 T 10-11-2016 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 A4G23_RS23520 e62f14f2d9cc6e7e4741188e59a34a92 695 SUPERFAMILY SSF81345 32 349 2.35E-67 T 10-11-2016 IPR029022 ABC transporter, BtuC-like A4G23_RS23520 e62f14f2d9cc6e7e4741188e59a34a92 695 Gene3D G3DSA:1.10.3470.10 32 350 2.6E-86 T 10-11-2016 IPR029022 ABC transporter, BtuC-like A4G23_RS23520 e62f14f2d9cc6e7e4741188e59a34a92 695 Gene3D G3DSA:1.10.3470.10 374 693 6.5E-89 T 10-11-2016 IPR029022 ABC transporter, BtuC-like A4G23_RS23520 e62f14f2d9cc6e7e4741188e59a34a92 695 SUPERFAMILY SSF81345 368 690 7.45E-71 T 10-11-2016 IPR029022 ABC transporter, BtuC-like A4G23_RS03915 d9f34d81e83dfb43b524bd5c7eb81676 432 SUPERFAMILY SSF53335 270 401 1.26E-17 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS03915 d9f34d81e83dfb43b524bd5c7eb81676 432 Gene3D G3DSA:3.30.950.10 104 196 3.5E-17 T 10-11-2016 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A4G23_RS03915 d9f34d81e83dfb43b524bd5c7eb81676 432 Gene3D G3DSA:3.40.50.150 271 401 6.4E-18 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS03915 d9f34d81e83dfb43b524bd5c7eb81676 432 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 9 196 6.2E-38 T 10-11-2016 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 A4G23_RS03915 d9f34d81e83dfb43b524bd5c7eb81676 432 Gene3D G3DSA:3.40.1010.10 5 103 5.3E-16 T 10-11-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A4G23_RS03915 d9f34d81e83dfb43b524bd5c7eb81676 432 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 286 334 1.8E-4 T 10-11-2016 A4G23_RS03915 d9f34d81e83dfb43b524bd5c7eb81676 432 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 15 182 4.2E-19 T 10-11-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A4G23_RS03915 d9f34d81e83dfb43b524bd5c7eb81676 432 SUPERFAMILY SSF53790 8 196 3.79E-31 T 10-11-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A4G23_RS20130 118b7b02bca5dbd9df70b78c0cee10c0 333 SUPERFAMILY SSF51735 3 183 2.6E-72 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS20130 118b7b02bca5dbd9df70b78c0cee10c0 333 Hamap MF_00435 Ketol-acid reductoisomerase [ilvC]. 2 329 44.774 T 10-11-2016 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 A4G23_RS20130 118b7b02bca5dbd9df70b78c0cee10c0 333 SUPERFAMILY SSF48179 184 330 8.33E-68 T 10-11-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A4G23_RS20130 118b7b02bca5dbd9df70b78c0cee10c0 333 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 184 327 1.1E-63 T 10-11-2016 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 A4G23_RS20130 118b7b02bca5dbd9df70b78c0cee10c0 333 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 15 178 1.1E-75 T 10-11-2016 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 A4G23_RS20130 118b7b02bca5dbd9df70b78c0cee10c0 333 Gene3D G3DSA:1.10.1040.10 30 326 4.7E-111 T 10-11-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A4G23_RS20130 118b7b02bca5dbd9df70b78c0cee10c0 333 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 15 327 1.1E-132 T 10-11-2016 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 A4G23_RS22360 eb403e8b69b6b3ef4a5eb7209612eb45 1118 Gene3D G3DSA:1.25.40.10 106 144 2.1E-6 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS22360 eb403e8b69b6b3ef4a5eb7209612eb45 1118 Gene3D G3DSA:1.25.40.10 189 249 2.1E-6 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS22360 eb403e8b69b6b3ef4a5eb7209612eb45 1118 Pfam PF00486 Transcriptional regulatory protein, C terminal 26 97 9.5E-10 T 10-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4G23_RS22360 eb403e8b69b6b3ef4a5eb7209612eb45 1118 Gene3D G3DSA:3.40.50.300 382 485 6.5E-5 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS22360 eb403e8b69b6b3ef4a5eb7209612eb45 1118 Gene3D G3DSA:1.10.10.10 14 99 2.0E-10 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS22360 eb403e8b69b6b3ef4a5eb7209612eb45 1118 Gene3D G3DSA:1.25.40.10 825 963 5.9E-5 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS22360 eb403e8b69b6b3ef4a5eb7209612eb45 1118 SUPERFAMILY SSF52540 372 627 2.72E-21 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS22360 eb403e8b69b6b3ef4a5eb7209612eb45 1118 SMART SM01043 105 250 2.3E-47 T 10-11-2016 IPR005158 Bacterial transcriptional activator domain A4G23_RS22360 eb403e8b69b6b3ef4a5eb7209612eb45 1118 SUPERFAMILY SSF48452 102 263 1.01E-36 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS22360 eb403e8b69b6b3ef4a5eb7209612eb45 1118 SMART SM00862 19 100 4.2E-8 T 10-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4G23_RS22360 eb403e8b69b6b3ef4a5eb7209612eb45 1118 Pfam PF03704 Bacterial transcriptional activator domain 105 250 8.5E-38 T 10-11-2016 IPR005158 Bacterial transcriptional activator domain A4G23_RS22360 eb403e8b69b6b3ef4a5eb7209612eb45 1118 PRINTS PR00364 Disease resistance protein signature 560 574 6.4E-5 T 10-11-2016 A4G23_RS22360 eb403e8b69b6b3ef4a5eb7209612eb45 1118 PRINTS PR00364 Disease resistance protein signature 400 415 6.4E-5 T 10-11-2016 A4G23_RS22360 eb403e8b69b6b3ef4a5eb7209612eb45 1118 PRINTS PR00364 Disease resistance protein signature 466 480 6.4E-5 T 10-11-2016 A4G23_RS22360 eb403e8b69b6b3ef4a5eb7209612eb45 1118 SUPERFAMILY SSF46894 6 84 1.84E-11 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS15260 73ab27e99366fdffac162d8aa76c9348 372 Pfam PF01171 PP-loop family 73 251 1.3E-38 T 10-11-2016 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 A4G23_RS15260 73ab27e99366fdffac162d8aa76c9348 372 Gene3D G3DSA:3.40.50.620 73 234 2.5E-14 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS15260 73ab27e99366fdffac162d8aa76c9348 372 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 59 361 20.302 T 10-11-2016 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 A4G23_RS15260 73ab27e99366fdffac162d8aa76c9348 372 Pfam PF09179 TilS substrate binding domain 300 367 7.2E-11 T 10-11-2016 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 A4G23_RS15260 73ab27e99366fdffac162d8aa76c9348 372 SUPERFAMILY SSF52402 73 283 4.19E-45 T 10-11-2016 A4G23_RS15260 73ab27e99366fdffac162d8aa76c9348 372 SUPERFAMILY SSF82829 263 367 6.93E-16 T 10-11-2016 A4G23_RS15260 73ab27e99366fdffac162d8aa76c9348 372 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 73 254 5.7E-44 T 10-11-2016 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 A4G23_RS16730 bb61c51d47b3f3e13b152e2f89d1d9de 126 Pfam PF00416 Ribosomal protein S13/S18 3 109 1.3E-30 T 10-11-2016 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS16730 bb61c51d47b3f3e13b152e2f89d1d9de 126 ProSitePatterns PS00646 Ribosomal protein S13 signature. 88 101 - T 10-11-2016 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS16730 bb61c51d47b3f3e13b152e2f89d1d9de 126 PIRSF PIRSF002134 1 125 8.6E-42 T 10-11-2016 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS16730 bb61c51d47b3f3e13b152e2f89d1d9de 126 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 115 2.9E-50 T 10-11-2016 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS16730 bb61c51d47b3f3e13b152e2f89d1d9de 126 Gene3D G3DSA:4.10.910.10 73 124 8.8E-25 T 10-11-2016 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS16730 bb61c51d47b3f3e13b152e2f89d1d9de 126 SUPERFAMILY SSF46946 2 122 4.06E-44 T 10-11-2016 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 A4G23_RS16730 bb61c51d47b3f3e13b152e2f89d1d9de 126 Gene3D G3DSA:1.10.8.50 1 72 4.6E-30 T 10-11-2016 A4G23_RS16730 bb61c51d47b3f3e13b152e2f89d1d9de 126 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 120 27.659 T 10-11-2016 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS11895 a8cae0ecf90b9b9c1756c53efaba94fa 1035 SUPERFAMILY SSF55874 53 148 3.51E-8 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS11895 a8cae0ecf90b9b9c1756c53efaba94fa 1035 Gene3D G3DSA:3.30.565.10 33 239 7.3E-17 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS01640 1b88e43b17c6759a7b95dc5c594eb8dc 412 PRINTS PR00714 Phosphomannose isomerase type I signature 4 22 2.2E-57 T 10-11-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 A4G23_RS01640 1b88e43b17c6759a7b95dc5c594eb8dc 412 PRINTS PR00714 Phosphomannose isomerase type I signature 223 238 2.2E-57 T 10-11-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 A4G23_RS01640 1b88e43b17c6759a7b95dc5c594eb8dc 412 PRINTS PR00714 Phosphomannose isomerase type I signature 80 101 2.2E-57 T 10-11-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 A4G23_RS01640 1b88e43b17c6759a7b95dc5c594eb8dc 412 PRINTS PR00714 Phosphomannose isomerase type I signature 258 277 2.2E-57 T 10-11-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 A4G23_RS01640 1b88e43b17c6759a7b95dc5c594eb8dc 412 PRINTS PR00714 Phosphomannose isomerase type I signature 125 148 2.2E-57 T 10-11-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 A4G23_RS01640 1b88e43b17c6759a7b95dc5c594eb8dc 412 PRINTS PR00714 Phosphomannose isomerase type I signature 239 258 2.2E-57 T 10-11-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 A4G23_RS01640 1b88e43b17c6759a7b95dc5c594eb8dc 412 PRINTS PR00714 Phosphomannose isomerase type I signature 277 296 2.2E-57 T 10-11-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 A4G23_RS01640 1b88e43b17c6759a7b95dc5c594eb8dc 412 PRINTS PR00714 Phosphomannose isomerase type I signature 31 46 2.2E-57 T 10-11-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 A4G23_RS01640 1b88e43b17c6759a7b95dc5c594eb8dc 412 Pfam PF01238 Phosphomannose isomerase type I 218 356 1.5E-24 T 10-11-2016 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 A4G23_RS01640 1b88e43b17c6759a7b95dc5c594eb8dc 412 Pfam PF01238 Phosphomannose isomerase type I 3 158 3.7E-35 T 10-11-2016 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 A4G23_RS01640 1b88e43b17c6759a7b95dc5c594eb8dc 412 Gene3D G3DSA:1.10.441.10 277 291 9.7E-18 T 10-11-2016 A4G23_RS01640 1b88e43b17c6759a7b95dc5c594eb8dc 412 Gene3D G3DSA:1.10.441.10 140 234 9.7E-18 T 10-11-2016 A4G23_RS01640 1b88e43b17c6759a7b95dc5c594eb8dc 412 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 4 384 4.2E-68 T 10-11-2016 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 A4G23_RS01640 1b88e43b17c6759a7b95dc5c594eb8dc 412 Gene3D G3DSA:2.60.120.10 7 139 4.3E-59 T 10-11-2016 IPR014710 RmlC-like jelly roll fold A4G23_RS01640 1b88e43b17c6759a7b95dc5c594eb8dc 412 Gene3D G3DSA:2.60.120.10 241 276 4.3E-59 T 10-11-2016 IPR014710 RmlC-like jelly roll fold A4G23_RS01640 1b88e43b17c6759a7b95dc5c594eb8dc 412 SUPERFAMILY SSF51182 3 385 2.41E-90 T 10-11-2016 IPR011051 RmlC-like cupin domain A4G23_RS01640 1b88e43b17c6759a7b95dc5c594eb8dc 412 Gene3D G3DSA:2.60.120.10 292 382 9.1E-12 T 10-11-2016 IPR014710 RmlC-like jelly roll fold A4G23_RS10200 5ac86ba5c8c653791b9bd0825cb62153 174 Gene3D G3DSA:3.30.565.10 79 170 4.5E-7 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS10200 5ac86ba5c8c653791b9bd0825cb62153 174 SUPERFAMILY SSF55874 80 168 1.06E-10 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS10200 5ac86ba5c8c653791b9bd0825cb62153 174 Pfam PF13581 Histidine kinase-like ATPase domain 57 155 1.4E-9 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS01655 29e3ac9210511969b87ac0323c0c7e5f 829 SUPERFAMILY SSF49303 178 280 4.89E-19 T 10-11-2016 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 A4G23_RS01655 29e3ac9210511969b87ac0323c0c7e5f 829 Gene3D G3DSA:3.20.20.80 279 516 3.3E-65 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS01655 29e3ac9210511969b87ac0323c0c7e5f 829 Gene3D G3DSA:3.20.20.80 555 622 3.3E-65 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS01655 29e3ac9210511969b87ac0323c0c7e5f 829 Gene3D G3DSA:2.60.120.260 20 174 2.2E-19 T 10-11-2016 IPR008979 Galactose-binding domain-like A4G23_RS01655 29e3ac9210511969b87ac0323c0c7e5f 829 SUPERFAMILY SSF51445 277 621 4.45E-106 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS01655 29e3ac9210511969b87ac0323c0c7e5f 829 Pfam PF00703 Glycosyl hydrolases family 2 223 280 3.6E-10 T 10-11-2016 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 A4G23_RS01655 29e3ac9210511969b87ac0323c0c7e5f 829 SUPERFAMILY SSF49785 4 175 2.21E-43 T 10-11-2016 IPR008979 Galactose-binding domain-like A4G23_RS01655 29e3ac9210511969b87ac0323c0c7e5f 829 Gene3D G3DSA:2.60.40.320 178 278 1.1E-22 T 10-11-2016 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 A4G23_RS06155 dd56954d4c7d7b6cd9f468f934687194 554 Gene3D G3DSA:3.60.21.10 475 519 2.5E-13 T 10-11-2016 IPR029052 Metallo-dependent phosphatase-like A4G23_RS06155 dd56954d4c7d7b6cd9f468f934687194 554 Gene3D G3DSA:3.60.21.10 157 440 2.5E-13 T 10-11-2016 IPR029052 Metallo-dependent phosphatase-like A4G23_RS06155 dd56954d4c7d7b6cd9f468f934687194 554 SUPERFAMILY SSF56300 156 523 9.93E-31 T 10-11-2016 IPR029052 Metallo-dependent phosphatase-like A4G23_RS06155 dd56954d4c7d7b6cd9f468f934687194 554 Pfam PF09423 PhoD-like phosphatase 161 518 5.9E-118 T 10-11-2016 IPR018946 Alkaline phosphatase D-related A4G23_RS06155 dd56954d4c7d7b6cd9f468f934687194 554 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 48 148 7.7E-32 T 10-11-2016 IPR032093 Phospholipase D, N-terminal A4G23_RS25995 0928dd7f772c1e814b687da881e5da6e 288 Gene3D G3DSA:1.10.10.60 56 114 4.3E-14 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS25995 0928dd7f772c1e814b687da881e5da6e 288 Gene3D G3DSA:3.20.80.10 115 283 5.6E-20 T 10-11-2016 IPR011256 Regulatory factor, effector binding domain A4G23_RS25995 0928dd7f772c1e814b687da881e5da6e 288 SUPERFAMILY SSF46689 3 53 7.53E-8 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS25995 0928dd7f772c1e814b687da881e5da6e 288 SUPERFAMILY SSF46689 55 106 2.33E-8 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS25995 0928dd7f772c1e814b687da881e5da6e 288 SMART SM00871 126 284 2.4E-24 T 10-11-2016 IPR010499 Bacterial transcription activator, effector binding A4G23_RS25995 0928dd7f772c1e814b687da881e5da6e 288 Pfam PF12833 Helix-turn-helix domain 25 103 1.0E-16 T 10-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4G23_RS25995 0928dd7f772c1e814b687da881e5da6e 288 SUPERFAMILY SSF55136 126 285 2.62E-20 T 10-11-2016 IPR011256 Regulatory factor, effector binding domain A4G23_RS25995 0928dd7f772c1e814b687da881e5da6e 288 Gene3D G3DSA:1.10.10.60 3 55 6.2E-16 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS25995 0928dd7f772c1e814b687da881e5da6e 288 Pfam PF06445 GyrI-like small molecule binding domain 126 283 8.4E-23 T 10-11-2016 IPR029442 GyrI-like small molecule binding domain A4G23_RS25995 0928dd7f772c1e814b687da881e5da6e 288 SMART SM00342 19 102 3.3E-22 T 10-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4G23_RS01050 46bd7429fd88c3c9fb133b48bef1a024 364 SUPERFAMILY SSF55931 2 349 3.83E-88 T 10-11-2016 A4G23_RS01050 46bd7429fd88c3c9fb133b48bef1a024 364 TIGRFAM TIGR02050 gshA_cyan_rel: carboxylate-amine ligase, YbdK family 3 288 7.3E-85 T 10-11-2016 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 A4G23_RS01050 46bd7429fd88c3c9fb133b48bef1a024 364 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 4 286 8.5E-54 T 10-11-2016 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 A4G23_RS01050 46bd7429fd88c3c9fb133b48bef1a024 364 Hamap MF_01609 Glutamate--cysteine ligase [gshA]. 1 364 74.903 T 10-11-2016 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 A4G23_RS00330 ed83bb42c5f3fb28a6545050e67028c2 1442 SUPERFAMILY SSF58104 40 170 4.71E-9 T 10-11-2016 A4G23_RS00330 ed83bb42c5f3fb28a6545050e67028c2 1442 SUPERFAMILY SSF58104 500 623 1.18E-11 T 10-11-2016 A4G23_RS00330 ed83bb42c5f3fb28a6545050e67028c2 1442 SMART SM00388 869 937 1.1E-21 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS00330 ed83bb42c5f3fb28a6545050e67028c2 1442 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 985 1106 8.2E-28 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS00330 ed83bb42c5f3fb28a6545050e67028c2 1442 Gene3D G3DSA:3.30.450.40 624 782 5.2E-22 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS00330 ed83bb42c5f3fb28a6545050e67028c2 1442 Pfam PF13185 GAF domain 647 782 1.7E-16 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS00330 ed83bb42c5f3fb28a6545050e67028c2 1442 SUPERFAMILY SSF58104 408 497 2.48E-5 T 10-11-2016 A4G23_RS00330 ed83bb42c5f3fb28a6545050e67028c2 1442 SMART SM00448 1314 1428 1.5E-35 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS00330 ed83bb42c5f3fb28a6545050e67028c2 1442 SMART SM00065 648 798 6.8E-11 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS00330 ed83bb42c5f3fb28a6545050e67028c2 1442 Pfam PF00072 Response regulator receiver domain 1316 1428 6.4E-25 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS00330 ed83bb42c5f3fb28a6545050e67028c2 1442 SUPERFAMILY SSF58104 132 260 1.67E-11 T 10-11-2016 A4G23_RS00330 ed83bb42c5f3fb28a6545050e67028c2 1442 Gene3D G3DSA:3.30.565.10 938 1110 1.2E-45 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS00330 ed83bb42c5f3fb28a6545050e67028c2 1442 Gene3D G3DSA:1.10.287.130 861 933 2.3E-16 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS00330 ed83bb42c5f3fb28a6545050e67028c2 1442 SUPERFAMILY SSF52172 1310 1434 1.42E-36 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS00330 ed83bb42c5f3fb28a6545050e67028c2 1442 SUPERFAMILY SSF55874 926 1110 1.11E-45 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS00330 ed83bb42c5f3fb28a6545050e67028c2 1442 SMART SM00304 204 256 9.5E-11 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS00330 ed83bb42c5f3fb28a6545050e67028c2 1442 SMART SM00304 20 72 0.0087 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS00330 ed83bb42c5f3fb28a6545050e67028c2 1442 SMART SM00304 572 624 1.2E-11 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS00330 ed83bb42c5f3fb28a6545050e67028c2 1442 SMART SM00304 112 164 9.6E-11 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS00330 ed83bb42c5f3fb28a6545050e67028c2 1442 SMART SM00304 480 532 4.9E-9 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS00330 ed83bb42c5f3fb28a6545050e67028c2 1442 SMART SM00304 388 440 6.5E-10 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS00330 ed83bb42c5f3fb28a6545050e67028c2 1442 SMART SM00304 296 348 6.7E-9 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS00330 ed83bb42c5f3fb28a6545050e67028c2 1442 SUPERFAMILY SSF55781 611 782 9.6E-29 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS00330 ed83bb42c5f3fb28a6545050e67028c2 1442 Pfam PF00672 HAMP domain 110 160 3.5E-6 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS00330 ed83bb42c5f3fb28a6545050e67028c2 1442 Pfam PF00672 HAMP domain 570 621 5.7E-7 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS00330 ed83bb42c5f3fb28a6545050e67028c2 1442 Pfam PF00672 HAMP domain 385 436 2.7E-6 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS00330 ed83bb42c5f3fb28a6545050e67028c2 1442 Pfam PF00672 HAMP domain 201 252 1.0E-6 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS00330 ed83bb42c5f3fb28a6545050e67028c2 1442 SUPERFAMILY SSF52172 1185 1258 1.24E-6 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS00330 ed83bb42c5f3fb28a6545050e67028c2 1442 Pfam PF00512 His Kinase A (phospho-acceptor) domain 870 937 3.5E-18 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS00330 ed83bb42c5f3fb28a6545050e67028c2 1442 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1068 1086 4.0E-15 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS00330 ed83bb42c5f3fb28a6545050e67028c2 1442 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1033 1047 4.0E-15 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS00330 ed83bb42c5f3fb28a6545050e67028c2 1442 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1092 1105 4.0E-15 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS00330 ed83bb42c5f3fb28a6545050e67028c2 1442 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1051 1061 4.0E-15 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS00330 ed83bb42c5f3fb28a6545050e67028c2 1442 Gene3D G3DSA:3.40.50.2300 1186 1258 1.1E-7 T 10-11-2016 A4G23_RS00330 ed83bb42c5f3fb28a6545050e67028c2 1442 SUPERFAMILY SSF47384 854 939 5.3E-21 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS00330 ed83bb42c5f3fb28a6545050e67028c2 1442 Gene3D G3DSA:3.40.50.2300 1304 1433 7.5E-40 T 10-11-2016 A4G23_RS00330 ed83bb42c5f3fb28a6545050e67028c2 1442 SUPERFAMILY SSF58104 224 401 2.28E-12 T 10-11-2016 A4G23_RS00330 ed83bb42c5f3fb28a6545050e67028c2 1442 SMART SM00387 984 1108 5.2E-41 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS25845 faf7059f2f51120ec097b47c2bee4174 248 Gene3D G3DSA:1.10.1060.10 111 242 4.3E-20 T 10-11-2016 A4G23_RS25845 faf7059f2f51120ec097b47c2bee4174 248 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 58 66 - T 10-11-2016 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 A4G23_RS25845 faf7059f2f51120ec097b47c2bee4174 248 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 4 119 9.5E-24 T 10-11-2016 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4G23_RS25845 faf7059f2f51120ec097b47c2bee4174 248 Gene3D G3DSA:3.10.20.30 1 110 2.3E-28 T 10-11-2016 IPR012675 Beta-grasp domain A4G23_RS25845 faf7059f2f51120ec097b47c2bee4174 248 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 158 169 - T 10-11-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4G23_RS25845 faf7059f2f51120ec097b47c2bee4174 248 Pfam PF13183 4Fe-4S dicluster domain 157 227 1.1E-10 T 10-11-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4G23_RS25845 faf7059f2f51120ec097b47c2bee4174 248 SUPERFAMILY SSF46548 118 241 4.19E-24 T 10-11-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 A4G23_RS25845 faf7059f2f51120ec097b47c2bee4174 248 SUPERFAMILY SSF54292 2 115 3.05E-20 T 10-11-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A4G23_RS10805 7edfeb794e7dbe10a859822c65058994 151 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 48 1.0E-20 T 10-11-2016 A4G23_RS10805 7edfeb794e7dbe10a859822c65058994 151 SUPERFAMILY SSF46785 1 59 3.22E-18 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS10805 7edfeb794e7dbe10a859822c65058994 151 Gene3D G3DSA:3.30.70.920 54 149 1.1E-24 T 10-11-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A4G23_RS10805 7edfeb794e7dbe10a859822c65058994 151 SUPERFAMILY SSF54909 63 149 4.16E-17 T 10-11-2016 IPR011008 Dimeric alpha-beta barrel A4G23_RS10805 7edfeb794e7dbe10a859822c65058994 151 ProSitePatterns PS00519 AsnC-type HTH domain signature. 19 45 - T 10-11-2016 IPR019885 Transcription regulator HTH, AsnC-type, conserved site A4G23_RS10805 7edfeb794e7dbe10a859822c65058994 151 Pfam PF01037 Lrp/AsnC ligand binding domain 67 140 1.1E-17 T 10-11-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A4G23_RS10805 7edfeb794e7dbe10a859822c65058994 151 Gene3D G3DSA:1.10.10.10 2 53 2.8E-26 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS10805 7edfeb794e7dbe10a859822c65058994 151 SMART SM00344 1 109 6.4E-42 T 10-11-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A4G23_RS10805 7edfeb794e7dbe10a859822c65058994 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 2.2E-18 T 10-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 A4G23_RS10805 7edfeb794e7dbe10a859822c65058994 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 2.2E-18 T 10-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 A4G23_RS10805 7edfeb794e7dbe10a859822c65058994 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 2.2E-18 T 10-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 A4G23_RS18215 168e6cc80d6ff795f272dbac703110bd 113 Gene3D G3DSA:1.10.1220.10 8 51 2.6E-5 T 10-11-2016 IPR013321 Arc-type ribbon-helix-helix GO:0006355 A4G23_RS18215 168e6cc80d6ff795f272dbac703110bd 113 SUPERFAMILY SSF47598 6 59 1.83E-9 T 10-11-2016 IPR010985 Ribbon-helix-helix GO:0006355 A4G23_RS13295 8265b48cece7b747f1642a698a36d0b6 166 SUPERFAMILY SSF117916 3 101 1.14E-22 T 10-11-2016 A4G23_RS13295 8265b48cece7b747f1642a698a36d0b6 166 Pfam PF01883 Domain of unknown function DUF59 17 83 5.3E-14 T 10-11-2016 IPR002744 Domain of unknown function DUF59 A4G23_RS13295 8265b48cece7b747f1642a698a36d0b6 166 TIGRFAM TIGR02159 PA_CoA_Oxy4: phenylacetate-CoA oxygenase, PaaJ subunit 18 165 1.2E-53 T 10-11-2016 IPR011883 Phenylacetate-CoA oxygenase, PaaJ subunit A4G23_RS00340 5ee5efd181218e09d50337aa762e21c4 147 Pfam PF00583 Acetyltransferase (GNAT) family 56 124 5.8E-9 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS00340 5ee5efd181218e09d50337aa762e21c4 147 SUPERFAMILY SSF55729 42 146 4.39E-22 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS00340 5ee5efd181218e09d50337aa762e21c4 147 Gene3D G3DSA:3.40.630.30 40 144 1.3E-21 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS21950 93a03fd8e158c21e81d271cae78a41c0 323 SUPERFAMILY SSF46785 3 57 4.54E-9 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS21950 93a03fd8e158c21e81d271cae78a41c0 323 Pfam PF08279 HTH domain 10 57 4.8E-13 T 10-11-2016 IPR013196 Helix-turn-helix, type 11 A4G23_RS21950 93a03fd8e158c21e81d271cae78a41c0 323 Gene3D G3DSA:1.10.10.10 2 61 6.3E-12 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS21950 93a03fd8e158c21e81d271cae78a41c0 323 Pfam PF13280 WYL domain 146 315 8.1E-29 T 10-11-2016 IPR026881 WYL domain A4G23_RS08955 7a0e33798a112fe52af64d4e8f851310 120 Pfam PF08239 Bacterial SH3 domain 52 116 1.4E-7 T 10-11-2016 IPR003646 SH3-like domain, bacterial-type A4G23_RS20905 465786d578d790ac3488c5fcdaee6779 154 SUPERFAMILY SSF89919 2 112 3.14E-31 T 10-11-2016 IPR023799 Ribosome-binding factor A domain A4G23_RS20905 465786d578d790ac3488c5fcdaee6779 154 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 2 116 19.707 T 10-11-2016 IPR000238 Ribosome-binding factor A GO:0006364 A4G23_RS20905 465786d578d790ac3488c5fcdaee6779 154 Gene3D G3DSA:3.30.300.20 3 117 1.1E-37 T 10-11-2016 IPR015946 K homology domain-like, alpha/beta A4G23_RS20905 465786d578d790ac3488c5fcdaee6779 154 Pfam PF02033 Ribosome-binding factor A 6 109 2.6E-25 T 10-11-2016 IPR000238 Ribosome-binding factor A GO:0006364 A4G23_RS20905 465786d578d790ac3488c5fcdaee6779 154 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 10 96 5.0E-25 T 10-11-2016 IPR000238 Ribosome-binding factor A GO:0006364 A4G23_RS20905 465786d578d790ac3488c5fcdaee6779 154 ProSitePatterns PS01319 Ribosome-binding factor A signature. 75 96 - T 10-11-2016 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 A4G23_RS20905 465786d578d790ac3488c5fcdaee6779 154 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 3 111 1.1E-23 T 10-11-2016 IPR000238 Ribosome-binding factor A GO:0006364 A4G23_RS19255 910bfdc5b648a5ab094374f150d70426 914 Gene3D G3DSA:1.10.390.10 418 570 3.4E-25 T 10-11-2016 A4G23_RS19255 910bfdc5b648a5ab094374f150d70426 914 Gene3D G3DSA:2.120.10.30 603 688 1.8E-4 T 10-11-2016 IPR011042 Six-bladed beta-propeller, TolB-like A4G23_RS19255 910bfdc5b648a5ab094374f150d70426 914 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 404 420 2.0E-17 T 10-11-2016 IPR023612 Peptidase M4 GO:0004222|GO:0006508 A4G23_RS19255 910bfdc5b648a5ab094374f150d70426 914 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 369 389 2.0E-17 T 10-11-2016 IPR023612 Peptidase M4 GO:0004222|GO:0006508 A4G23_RS19255 910bfdc5b648a5ab094374f150d70426 914 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 425 436 2.0E-17 T 10-11-2016 IPR023612 Peptidase M4 GO:0004222|GO:0006508 A4G23_RS19255 910bfdc5b648a5ab094374f150d70426 914 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 496 512 2.0E-17 T 10-11-2016 IPR023612 Peptidase M4 GO:0004222|GO:0006508 A4G23_RS19255 910bfdc5b648a5ab094374f150d70426 914 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 252 413 1.6E-35 T 10-11-2016 IPR013856 Peptidase M4 domain GO:0004222 A4G23_RS19255 910bfdc5b648a5ab094374f150d70426 914 SUPERFAMILY SSF55486 251 570 3.3E-61 T 10-11-2016 A4G23_RS19255 910bfdc5b648a5ab094374f150d70426 914 Gene3D G3DSA:3.10.170.10 252 416 1.2E-35 T 10-11-2016 IPR013856 Peptidase M4 domain GO:0004222 A4G23_RS19255 910bfdc5b648a5ab094374f150d70426 914 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 416 570 3.0E-29 T 10-11-2016 IPR001570 Peptidase M4, C-terminal GO:0004222 A4G23_RS19260 007d490de21bd4950e6c4c65bf29280e 217 SMART SM00421 153 210 3.3E-23 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS19260 007d490de21bd4950e6c4c65bf29280e 217 Gene3D G3DSA:3.40.50.2300 1 155 4.5E-31 T 10-11-2016 A4G23_RS19260 007d490de21bd4950e6c4c65bf29280e 217 Pfam PF00072 Response regulator receiver domain 1 108 1.4E-23 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS19260 007d490de21bd4950e6c4c65bf29280e 217 SMART SM00448 1 110 6.9E-22 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS19260 007d490de21bd4950e6c4c65bf29280e 217 SUPERFAMILY SSF52172 1 128 3.98E-27 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS19260 007d490de21bd4950e6c4c65bf29280e 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 1.4E-12 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS19260 007d490de21bd4950e6c4c65bf29280e 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 1.4E-12 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS19260 007d490de21bd4950e6c4c65bf29280e 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 1.4E-12 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS19260 007d490de21bd4950e6c4c65bf29280e 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 209 6.0E-18 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS19260 007d490de21bd4950e6c4c65bf29280e 217 SUPERFAMILY SSF46894 147 216 2.86E-21 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS19260 007d490de21bd4950e6c4c65bf29280e 217 Gene3D G3DSA:1.10.10.10 156 215 1.1E-27 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS19565 e44dcc5a125433d0d6ce42641cbbada3 532 Gene3D G3DSA:3.40.50.300 99 383 3.2E-107 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS19565 e44dcc5a125433d0d6ce42641cbbada3 532 Gene3D G3DSA:2.40.30.20 5 97 7.1E-28 T 10-11-2016 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 A4G23_RS19565 e44dcc5a125433d0d6ce42641cbbada3 532 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 4 513 48.192 T 10-11-2016 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 A4G23_RS19565 e44dcc5a125433d0d6ce42641cbbada3 532 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 153 376 3.9E-66 T 10-11-2016 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A4G23_RS19565 e44dcc5a125433d0d6ce42641cbbada3 532 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 6 512 8.9E-240 T 10-11-2016 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 A4G23_RS19565 e44dcc5a125433d0d6ce42641cbbada3 532 SUPERFAMILY SSF50615 27 98 2.88E-21 T 10-11-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A4G23_RS19565 e44dcc5a125433d0d6ce42641cbbada3 532 SUPERFAMILY SSF52540 100 382 7.18E-92 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS19565 e44dcc5a125433d0d6ce42641cbbada3 532 Gene3D G3DSA:1.20.150.20 384 512 7.4E-52 T 10-11-2016 A4G23_RS19565 e44dcc5a125433d0d6ce42641cbbada3 532 SUPERFAMILY SSF47917 384 512 1.46E-46 T 10-11-2016 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A4G23_RS19565 e44dcc5a125433d0d6ce42641cbbada3 532 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 383 508 2.1E-47 T 10-11-2016 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A4G23_RS19565 e44dcc5a125433d0d6ce42641cbbada3 532 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 367 376 - T 10-11-2016 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A4G23_RS19565 e44dcc5a125433d0d6ce42641cbbada3 532 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 30 96 4.3E-13 T 10-11-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A4G23_RS08230 c94b39d4dbef68f71cd5268f25a6c793 506 Pfam PF05235 CHAD domain 222 454 1.8E-44 T 10-11-2016 IPR007899 CHAD domain A4G23_RS08230 c94b39d4dbef68f71cd5268f25a6c793 506 Pfam PF01928 CYTH domain 6 179 4.5E-17 T 10-11-2016 IPR023577 CYTH domain Reactome: R-HSA-196819 A4G23_RS08230 c94b39d4dbef68f71cd5268f25a6c793 506 SMART SM00880 222 488 4.9E-55 T 10-11-2016 IPR007899 CHAD domain A4G23_RS08230 c94b39d4dbef68f71cd5268f25a6c793 506 SMART SM01118 5 201 9.5E-19 T 10-11-2016 IPR023577 CYTH domain Reactome: R-HSA-196819 A4G23_RS08230 c94b39d4dbef68f71cd5268f25a6c793 506 SUPERFAMILY SSF55154 6 206 8.94E-46 T 10-11-2016 IPR033469 CYTH-like domain Reactome: R-HSA-196819 A4G23_RS08230 c94b39d4dbef68f71cd5268f25a6c793 506 Gene3D G3DSA:2.40.320.10 6 206 2.7E-58 T 10-11-2016 IPR023577 CYTH domain Reactome: R-HSA-196819 A4G23_RS07215 a4c521f2409a456b500844754a00a75e 158 SUPERFAMILY SSF55729 7 152 2.92E-22 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS07215 a4c521f2409a456b500844754a00a75e 158 Pfam PF00583 Acetyltransferase (GNAT) family 60 135 2.0E-10 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS07215 a4c521f2409a456b500844754a00a75e 158 Gene3D G3DSA:3.40.630.30 7 154 2.0E-24 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS09785 14a21aa247e0157b671e6aa824cfcecd 286 PRINTS PR00164 ABC-2 type transport system membrane protein signature 83 105 9.0E-6 T 10-11-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 A4G23_RS09785 14a21aa247e0157b671e6aa824cfcecd 286 PRINTS PR00164 ABC-2 type transport system membrane protein signature 52 73 9.0E-6 T 10-11-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 A4G23_RS09785 14a21aa247e0157b671e6aa824cfcecd 286 PRINTS PR00164 ABC-2 type transport system membrane protein signature 196 215 9.0E-6 T 10-11-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 A4G23_RS09785 14a21aa247e0157b671e6aa824cfcecd 286 PRINTS PR00164 ABC-2 type transport system membrane protein signature 159 183 9.0E-6 T 10-11-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 A4G23_RS09785 14a21aa247e0157b671e6aa824cfcecd 286 Pfam PF01061 ABC-2 type transporter 41 244 2.6E-16 T 10-11-2016 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A4G23_RS19220 51c87e0639776d6b877e4f417e4831e8 348 SMART SM00387 228 344 1.2E-35 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS19220 51c87e0639776d6b877e4f417e4831e8 348 SUPERFAMILY SSF55874 160 342 2.49E-36 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS19220 51c87e0639776d6b877e4f417e4831e8 348 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 229 342 3.6E-23 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS19220 51c87e0639776d6b877e4f417e4831e8 348 Gene3D G3DSA:1.10.287.130 96 156 7.4E-16 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS19220 51c87e0639776d6b877e4f417e4831e8 348 SUPERFAMILY SSF47384 89 170 1.43E-17 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS19220 51c87e0639776d6b877e4f417e4831e8 348 SMART SM00304 52 105 1.3E-11 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS19220 51c87e0639776d6b877e4f417e4831e8 348 PRINTS PR00344 Bacterial sensor protein C-terminal signature 328 341 6.6E-12 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS19220 51c87e0639776d6b877e4f417e4831e8 348 PRINTS PR00344 Bacterial sensor protein C-terminal signature 267 281 6.6E-12 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS19220 51c87e0639776d6b877e4f417e4831e8 348 PRINTS PR00344 Bacterial sensor protein C-terminal signature 305 323 6.6E-12 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS19220 51c87e0639776d6b877e4f417e4831e8 348 Pfam PF00672 HAMP domain 35 101 3.3E-13 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS19220 51c87e0639776d6b877e4f417e4831e8 348 SMART SM00388 106 170 1.2E-16 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS19220 51c87e0639776d6b877e4f417e4831e8 348 Gene3D G3DSA:3.30.565.10 157 189 2.3E-38 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS19220 51c87e0639776d6b877e4f417e4831e8 348 Gene3D G3DSA:3.30.565.10 221 343 2.3E-38 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS19220 51c87e0639776d6b877e4f417e4831e8 348 SUPERFAMILY SSF158472 54 101 1.83E-10 T 10-11-2016 A4G23_RS19220 51c87e0639776d6b877e4f417e4831e8 348 Pfam PF00512 His Kinase A (phospho-acceptor) domain 107 170 1.8E-14 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS04265 76aebbd5b4997593ae985a34e3ae613c 123 SUPERFAMILY SSF54534 16 123 7.66E-40 T 10-11-2016 A4G23_RS04265 76aebbd5b4997593ae985a34e3ae613c 123 Gene3D G3DSA:3.10.50.40 9 123 1.9E-42 T 10-11-2016 A4G23_RS04265 76aebbd5b4997593ae985a34e3ae613c 123 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 30 120 3.2E-32 T 10-11-2016 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 A4G23_RS20625 9073f157a0d749886551e5c4d09119c3 341 Pfam PF00005 ABC transporter 18 160 3.0E-30 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS20625 9073f157a0d749886551e5c4d09119c3 341 Gene3D G3DSA:3.40.50.300 2 232 1.6E-72 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS20625 9073f157a0d749886551e5c4d09119c3 341 SUPERFAMILY SSF52540 2 241 1.47E-76 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS20625 9073f157a0d749886551e5c4d09119c3 341 SMART SM00382 27 210 7.2E-17 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS20625 9073f157a0d749886551e5c4d09119c3 341 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS20625 9073f157a0d749886551e5c4d09119c3 341 Pfam PF08402 TOBE domain 268 340 5.0E-9 T 10-11-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 A4G23_RS20625 9073f157a0d749886551e5c4d09119c3 341 SUPERFAMILY SSF50331 237 340 7.37E-7 T 10-11-2016 IPR008995 Molybdate/tungstate binding, C-terminal A4G23_RS09055 94545b528548448bf4cb71e35f612506 416 Gene3D G3DSA:1.10.260.40 10 85 1.4E-9 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS09055 94545b528548448bf4cb71e35f612506 416 Pfam PF01381 Helix-turn-helix 19 63 1.2E-7 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS09055 94545b528548448bf4cb71e35f612506 416 Gene3D G3DSA:1.25.40.10 141 285 8.5E-4 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS09055 94545b528548448bf4cb71e35f612506 416 Gene3D G3DSA:1.25.40.10 333 366 8.5E-4 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS09055 94545b528548448bf4cb71e35f612506 416 SMART SM00530 12 65 2.2E-7 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS09055 94545b528548448bf4cb71e35f612506 416 SUPERFAMILY SSF47413 6 68 4.5E-9 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS22325 780617e6539ccb85230c845af9198a6e 424 SUPERFAMILY SSF48264 6 424 1.96E-98 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS22325 780617e6539ccb85230c845af9198a6e 424 Pfam PF00067 Cytochrome P450 18 409 7.4E-74 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS22325 780617e6539ccb85230c845af9198a6e 424 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 366 375 - T 10-11-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A4G23_RS22325 780617e6539ccb85230c845af9198a6e 424 Gene3D G3DSA:1.10.630.10 7 424 6.3E-111 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS22325 780617e6539ccb85230c845af9198a6e 424 PRINTS PR00385 P450 superfamily signature 237 254 1.2E-10 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS22325 780617e6539ccb85230c845af9198a6e 424 PRINTS PR00385 P450 superfamily signature 289 300 1.2E-10 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS22325 780617e6539ccb85230c845af9198a6e 424 PRINTS PR00385 P450 superfamily signature 373 384 1.2E-10 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS22325 780617e6539ccb85230c845af9198a6e 424 PRINTS PR00385 P450 superfamily signature 364 373 1.2E-10 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS22325 780617e6539ccb85230c845af9198a6e 424 PRINTS PR00463 E-class P450 group I signature 363 373 3.5E-21 T 10-11-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS22325 780617e6539ccb85230c845af9198a6e 424 PRINTS PR00463 E-class P450 group I signature 15 34 3.5E-21 T 10-11-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS22325 780617e6539ccb85230c845af9198a6e 424 PRINTS PR00463 E-class P450 group I signature 328 352 3.5E-21 T 10-11-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS22325 780617e6539ccb85230c845af9198a6e 424 PRINTS PR00463 E-class P450 group I signature 373 396 3.5E-21 T 10-11-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS22325 780617e6539ccb85230c845af9198a6e 424 PRINTS PR00463 E-class P450 group I signature 246 272 3.5E-21 T 10-11-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS22325 780617e6539ccb85230c845af9198a6e 424 PRINTS PR00463 E-class P450 group I signature 226 243 3.5E-21 T 10-11-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS11595 c61024f5a1f437c48b0818c20e4af36c 322 SMART SM00382 31 214 8.1E-6 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS11595 c61024f5a1f437c48b0818c20e4af36c 322 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 14 311 1.0E-102 T 10-11-2016 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 A4G23_RS11595 c61024f5a1f437c48b0818c20e4af36c 322 SUPERFAMILY SSF52540 6 227 1.51E-54 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS11595 c61024f5a1f437c48b0818c20e4af36c 322 Pfam PF13732 Domain of unknown function (DUF4162) 220 309 3.6E-8 T 10-11-2016 IPR025302 Domain of unknown function DUF4162 A4G23_RS11595 c61024f5a1f437c48b0818c20e4af36c 322 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS11595 c61024f5a1f437c48b0818c20e4af36c 322 Pfam PF00005 ABC transporter 22 165 7.2E-22 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS11595 c61024f5a1f437c48b0818c20e4af36c 322 Gene3D G3DSA:3.40.50.300 3 230 6.0E-62 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS08800 3b9674ca301dbf79b793fcf48bc936c3 367 Pfam PF01636 Phosphotransferase enzyme family 53 212 1.2E-18 T 10-11-2016 IPR002575 Aminoglycoside phosphotransferase A4G23_RS08800 3b9674ca301dbf79b793fcf48bc936c3 367 Gene3D G3DSA:3.90.1200.10 125 211 1.1E-13 T 10-11-2016 A4G23_RS08800 3b9674ca301dbf79b793fcf48bc936c3 367 Gene3D G3DSA:3.90.1200.10 254 318 1.1E-13 T 10-11-2016 A4G23_RS08800 3b9674ca301dbf79b793fcf48bc936c3 367 SUPERFAMILY SSF56112 27 209 5.2E-19 T 10-11-2016 IPR011009 Protein kinase-like domain A4G23_RS08800 3b9674ca301dbf79b793fcf48bc936c3 367 SUPERFAMILY SSF56112 253 313 5.2E-19 T 10-11-2016 IPR011009 Protein kinase-like domain A4G23_RS03195 175c921be31c868ecd34d5aca6d2b60e 232 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 79 5.1E-15 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS03195 175c921be31c868ecd34d5aca6d2b60e 232 SMART SM00345 21 79 1.7E-13 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS03195 175c921be31c868ecd34d5aca6d2b60e 232 SUPERFAMILY SSF48008 85 219 5.23E-25 T 10-11-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal A4G23_RS03195 175c921be31c868ecd34d5aca6d2b60e 232 SUPERFAMILY SSF46785 13 83 3.14E-17 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS03195 175c921be31c868ecd34d5aca6d2b60e 232 Gene3D G3DSA:1.10.10.10 16 80 2.1E-21 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS03195 175c921be31c868ecd34d5aca6d2b60e 232 Gene3D G3DSA:1.20.120.530 85 222 1.3E-34 T 10-11-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal A4G23_RS03195 175c921be31c868ecd34d5aca6d2b60e 232 Pfam PF07729 FCD domain 89 210 1.7E-12 T 10-11-2016 IPR011711 GntR, C-terminal A4G23_RS03195 175c921be31c868ecd34d5aca6d2b60e 232 SMART SM00895 89 211 5.2E-13 T 10-11-2016 IPR011711 GntR, C-terminal A4G23_RS23150 922c7cc8b6f853f3f963a1c8e574de95 248 SUPERFAMILY SSF53800 7 238 4.69E-46 T 10-11-2016 A4G23_RS23150 922c7cc8b6f853f3f963a1c8e574de95 248 Pfam PF01903 CbiX 139 231 6.8E-13 T 10-11-2016 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 A4G23_RS23150 922c7cc8b6f853f3f963a1c8e574de95 248 Pfam PF01903 CbiX 14 115 4.5E-20 T 10-11-2016 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 A4G23_RS23150 922c7cc8b6f853f3f963a1c8e574de95 248 Gene3D G3DSA:3.40.50.1400 7 122 4.6E-25 T 10-11-2016 A4G23_RS23150 922c7cc8b6f853f3f963a1c8e574de95 248 Gene3D G3DSA:3.40.50.1400 131 240 6.1E-19 T 10-11-2016 A4G23_RS07615 161a3f5e1130bfad3ac146f4936ac8a9 312 SUPERFAMILY SSF52317 56 245 1.06E-29 T 10-11-2016 IPR029062 Class I glutamine amidotransferase-like A4G23_RS07615 161a3f5e1130bfad3ac146f4936ac8a9 312 ProDom PD037892 HOMOSERINE O-SUCCINYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIOSYNTHESIS TRANSSUCCINYLASE HTS METHIONINE O- AMINO-ACID 59 215 4.0E-27 T 10-11-2016 A4G23_RS07615 161a3f5e1130bfad3ac146f4936ac8a9 312 Gene3D G3DSA:3.40.50.880 64 288 6.5E-40 T 10-11-2016 IPR029062 Class I glutamine amidotransferase-like A4G23_RS07615 161a3f5e1130bfad3ac146f4936ac8a9 312 Pfam PF04204 Homoserine O-succinyltransferase 65 287 1.4E-38 T 10-11-2016 IPR005697 Homoserine O-succinyltransferase GO:0005737|GO:0008899|GO:0019281 KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 A4G23_RS25475 8f5aece5439b3f80636f05d260d84816 419 Gene3D G3DSA:1.20.1250.20 241 415 1.4E-19 T 10-11-2016 A4G23_RS25475 8f5aece5439b3f80636f05d260d84816 419 SUPERFAMILY SSF103473 18 417 4.19E-43 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS25475 8f5aece5439b3f80636f05d260d84816 419 Pfam PF00083 Sugar (and other) transporter 53 181 1.0E-5 T 10-11-2016 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 A4G23_RS25475 8f5aece5439b3f80636f05d260d84816 419 Pfam PF07690 Major Facilitator Superfamily 245 416 4.1E-14 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS25475 8f5aece5439b3f80636f05d260d84816 419 Gene3D G3DSA:1.20.1250.20 17 214 5.6E-14 T 10-11-2016 A4G23_RS11235 4c7a2bdca7a375bebf3c0c8b8cc33859 438 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 364 373 - T 10-11-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A4G23_RS11235 4c7a2bdca7a375bebf3c0c8b8cc33859 438 PRINTS PR00359 B-class P450 signature 93 104 6.9E-42 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS11235 4c7a2bdca7a375bebf3c0c8b8cc33859 438 PRINTS PR00359 B-class P450 signature 206 228 6.9E-42 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS11235 4c7a2bdca7a375bebf3c0c8b8cc33859 438 PRINTS PR00359 B-class P450 signature 341 356 6.9E-42 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS11235 4c7a2bdca7a375bebf3c0c8b8cc33859 438 PRINTS PR00359 B-class P450 signature 371 382 6.9E-42 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS11235 4c7a2bdca7a375bebf3c0c8b8cc33859 438 PRINTS PR00359 B-class P450 signature 313 340 6.9E-42 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS11235 4c7a2bdca7a375bebf3c0c8b8cc33859 438 PRINTS PR00359 B-class P450 signature 362 371 6.9E-42 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS11235 4c7a2bdca7a375bebf3c0c8b8cc33859 438 PRINTS PR00359 B-class P450 signature 295 306 6.9E-42 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS11235 4c7a2bdca7a375bebf3c0c8b8cc33859 438 Pfam PF00067 Cytochrome P450 6 391 1.8E-25 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS11235 4c7a2bdca7a375bebf3c0c8b8cc33859 438 SUPERFAMILY SSF48264 2 425 2.36E-88 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS11235 4c7a2bdca7a375bebf3c0c8b8cc33859 438 Gene3D G3DSA:1.10.630.10 4 426 6.8E-115 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS12385 db0f7836bd66e7654b7138159e116db6 141 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 141 29.731 T 10-11-2016 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 A4G23_RS12385 db0f7836bd66e7654b7138159e116db6 141 SUPERFAMILY SSF69500 1 140 1.44E-44 T 10-11-2016 IPR023509 D-Tyr tRNAtyr deacylase-like domain A4G23_RS12385 db0f7836bd66e7654b7138159e116db6 141 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 141 2.0E-39 T 10-11-2016 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 A4G23_RS12385 db0f7836bd66e7654b7138159e116db6 141 Gene3D G3DSA:3.50.80.10 1 140 1.7E-52 T 10-11-2016 IPR023509 D-Tyr tRNAtyr deacylase-like domain A4G23_RS12385 db0f7836bd66e7654b7138159e116db6 141 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 140 3.5E-49 T 10-11-2016 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 A4G23_RS16760 35982618635fcfefc51d3a4dd33f9178 558 SUPERFAMILY SSF52540 15 235 2.47E-36 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS16760 35982618635fcfefc51d3a4dd33f9178 558 Pfam PF00005 ABC transporter 21 191 3.0E-20 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS16760 35982618635fcfefc51d3a4dd33f9178 558 Pfam PF00005 ABC transporter 348 494 7.9E-12 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS16760 35982618635fcfefc51d3a4dd33f9178 558 Gene3D G3DSA:3.40.50.300 348 545 3.0E-27 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS16760 35982618635fcfefc51d3a4dd33f9178 558 Gene3D G3DSA:3.40.50.300 163 280 2.2E-39 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS16760 35982618635fcfefc51d3a4dd33f9178 558 Gene3D G3DSA:3.40.50.300 3 124 2.2E-39 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS16760 35982618635fcfefc51d3a4dd33f9178 558 SUPERFAMILY SSF52540 347 541 4.99E-29 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS16760 35982618635fcfefc51d3a4dd33f9178 558 SMART SM00382 356 555 2.6E-8 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS16760 35982618635fcfefc51d3a4dd33f9178 558 SMART SM00382 29 236 1.8E-18 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS08705 ff45a6e8a8b25771f6b355991440e885 284 SUPERFAMILY SSF63817 141 271 1.14E-5 T 10-11-2016 IPR023365 Sortase domain A4G23_RS08705 ff45a6e8a8b25771f6b355991440e885 284 Pfam PF04203 Sortase family 174 280 3.7E-7 T 10-11-2016 IPR005754 Sortase family A4G23_RS15870 93c591cf3d2f41bc1060eebd7d753f3d 483 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 6 448 7.8E-137 T 10-11-2016 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 A4G23_RS15870 93c591cf3d2f41bc1060eebd7d753f3d 483 SUPERFAMILY SSF50475 3 317 7.45E-115 T 10-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 A4G23_RS15870 93c591cf3d2f41bc1060eebd7d753f3d 483 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 10 423 2.9E-158 T 10-11-2016 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 A4G23_RS15870 93c591cf3d2f41bc1060eebd7d753f3d 483 TIGRFAM TIGR03701 mena_SCO4490: menaquinone biosynthesis decarboxylase, SCO4490 family 9 440 3.9E-196 T 10-11-2016 IPR022390 4-hydroxybenzoate decarboxylase subunit C GO:0016831 A4G23_RS15870 93c591cf3d2f41bc1060eebd7d753f3d 483 SUPERFAMILY SSF143968 318 483 4.58E-55 T 10-11-2016 A4G23_RS15870 93c591cf3d2f41bc1060eebd7d753f3d 483 Gene3D G3DSA:1.20.5.570 448 483 1.1E-6 T 10-11-2016 A4G23_RS15870 93c591cf3d2f41bc1060eebd7d753f3d 483 Gene3D G3DSA:3.40.1670.10 332 447 4.5E-38 T 10-11-2016 A4G23_RS10375 02b7335f15bcdab1b6da2d8a770789d6 183 Pfam PF04417 Protein of unknown function (DUF501) 36 156 2.6E-36 T 10-11-2016 IPR007511 Protein of unknown function DUF501 A4G23_RS10085 68fbc6f5f9e0e76937a4b9e06d82a4e2 385 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 235 384 1.3E-48 T 10-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4G23_RS10085 68fbc6f5f9e0e76937a4b9e06d82a4e2 385 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 130 142 - T 10-11-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A4G23_RS10085 68fbc6f5f9e0e76937a4b9e06d82a4e2 385 Gene3D G3DSA:1.10.540.10 12 124 5.4E-34 T 10-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 A4G23_RS10085 68fbc6f5f9e0e76937a4b9e06d82a4e2 385 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 343 362 - T 10-11-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A4G23_RS10085 68fbc6f5f9e0e76937a4b9e06d82a4e2 385 Gene3D G3DSA:1.20.140.10 224 384 3.2E-67 T 10-11-2016 A4G23_RS10085 68fbc6f5f9e0e76937a4b9e06d82a4e2 385 Gene3D G3DSA:2.40.110.10 128 223 7.5E-42 T 10-11-2016 A4G23_RS10085 68fbc6f5f9e0e76937a4b9e06d82a4e2 385 SUPERFAMILY SSF47203 233 384 1.65E-56 T 10-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4G23_RS10085 68fbc6f5f9e0e76937a4b9e06d82a4e2 385 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 13 124 4.5E-30 T 10-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 A4G23_RS10085 68fbc6f5f9e0e76937a4b9e06d82a4e2 385 SUPERFAMILY SSF56645 12 247 1.7E-80 T 10-11-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 A4G23_RS10085 68fbc6f5f9e0e76937a4b9e06d82a4e2 385 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 128 223 9.9E-28 T 10-11-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 A4G23_RS24865 581f7765743d466782ee42fad1567a35 353 Gene3D G3DSA:3.40.50.1970 7 157 3.2E-28 T 10-11-2016 A4G23_RS24865 581f7765743d466782ee42fad1567a35 353 PIRSF PIRSF000112 2 353 1.9E-92 T 10-11-2016 A4G23_RS24865 581f7765743d466782ee42fad1567a35 353 Gene3D G3DSA:1.20.1090.10 159 348 3.9E-60 T 10-11-2016 A4G23_RS24865 581f7765743d466782ee42fad1567a35 353 Pfam PF13685 Iron-containing alcohol dehydrogenase 16 270 6.5E-62 T 10-11-2016 IPR032837 Glycerol-1-phosphate dehydrogenase KEGG: 00564+1.1.1.261|KEGG: 00630+1.1.1.26|MetaCyc: PWY-6349|MetaCyc: PWY-7294|MetaCyc: PWY-7295 A4G23_RS24865 581f7765743d466782ee42fad1567a35 353 SUPERFAMILY SSF56796 4 344 1.03E-57 T 10-11-2016 A4G23_RS00420 b5d0a0e088defe1a8c23be9dde0b0c14 249 SMART SM00020 49 243 1.9E-16 T 10-11-2016 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 A4G23_RS00420 b5d0a0e088defe1a8c23be9dde0b0c14 249 Pfam PF00089 Trypsin 57 243 2.5E-27 T 10-11-2016 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 A4G23_RS00420 b5d0a0e088defe1a8c23be9dde0b0c14 249 Gene3D G3DSA:2.40.10.10 119 246 6.8E-19 T 10-11-2016 A4G23_RS00420 b5d0a0e088defe1a8c23be9dde0b0c14 249 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 119 133 3.2E-8 T 10-11-2016 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 A4G23_RS00420 b5d0a0e088defe1a8c23be9dde0b0c14 249 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 201 213 3.2E-8 T 10-11-2016 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 A4G23_RS00420 b5d0a0e088defe1a8c23be9dde0b0c14 249 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 74 89 3.2E-8 T 10-11-2016 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 A4G23_RS00420 b5d0a0e088defe1a8c23be9dde0b0c14 249 Gene3D G3DSA:2.40.10.10 57 106 3.9E-12 T 10-11-2016 A4G23_RS00420 b5d0a0e088defe1a8c23be9dde0b0c14 249 SUPERFAMILY SSF50494 42 248 4.89E-36 T 10-11-2016 IPR009003 Peptidase S1, PA clan A4G23_RS03090 0c0559d2a463b9576e0d581084120eda 831 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 532 632 2.1E-15 T 10-11-2016 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS03090 0c0559d2a463b9576e0d581084120eda 831 Gene3D G3DSA:3.40.120.10 552 628 3.5E-12 T 10-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS03090 0c0559d2a463b9576e0d581084120eda 831 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 639 740 1.9E-4 T 10-11-2016 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS03090 0c0559d2a463b9576e0d581084120eda 831 Gene3D G3DSA:2.160.10.10 235 366 5.0E-29 T 10-11-2016 A4G23_RS03090 0c0559d2a463b9576e0d581084120eda 831 Gene3D G3DSA:3.40.120.10 633 726 5.8E-13 T 10-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS03090 0c0559d2a463b9576e0d581084120eda 831 Gene3D G3DSA:3.30.310.50 752 828 2.0E-12 T 10-11-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS03090 0c0559d2a463b9576e0d581084120eda 831 Gene3D G3DSA:3.90.550.10 1 234 4.3E-77 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS03090 0c0559d2a463b9576e0d581084120eda 831 Pfam PF00483 Nucleotidyl transferase 2 233 1.2E-54 T 10-11-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A4G23_RS03090 0c0559d2a463b9576e0d581084120eda 831 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 384 511 3.1E-13 T 10-11-2016 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS03090 0c0559d2a463b9576e0d581084120eda 831 SUPERFAMILY SSF53448 269 325 9.62E-82 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS03090 0c0559d2a463b9576e0d581084120eda 831 SUPERFAMILY SSF53448 1 237 9.62E-82 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS03090 0c0559d2a463b9576e0d581084120eda 831 SUPERFAMILY SSF53738 530 634 3.45E-13 T 10-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS03090 0c0559d2a463b9576e0d581084120eda 831 SUPERFAMILY SSF51161 244 433 1.43E-34 T 10-11-2016 IPR011004 Trimeric LpxA-like A4G23_RS03090 0c0559d2a463b9576e0d581084120eda 831 SUPERFAMILY SSF55957 744 828 2.54E-13 T 10-11-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS03090 0c0559d2a463b9576e0d581084120eda 831 Gene3D G3DSA:3.40.120.10 384 510 6.6E-12 T 10-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS03090 0c0559d2a463b9576e0d581084120eda 831 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 250 283 1.0E-4 T 10-11-2016 IPR001451 Hexapeptide repeat A4G23_RS03090 0c0559d2a463b9576e0d581084120eda 831 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 285 319 1.3E-4 T 10-11-2016 IPR001451 Hexapeptide repeat A4G23_RS03090 0c0559d2a463b9576e0d581084120eda 831 SUPERFAMILY SSF53738 637 741 1.92E-11 T 10-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS14535 30849d9b427ab2985dc7e79a8b4969a2 268 Pfam PF03301 Tryptophan 2,3-dioxygenase 5 268 1.2E-75 T 10-11-2016 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 A4G23_RS14535 30849d9b427ab2985dc7e79a8b4969a2 268 Hamap MF_01972 Tryptophan 2,3-dioxygenase [kynA]. 5 268 36.815 T 10-11-2016 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 A4G23_RS14535 30849d9b427ab2985dc7e79a8b4969a2 268 SUPERFAMILY SSF140959 11 267 4.71E-82 T 10-11-2016 A4G23_RS00885 087d3534de5f6b1576cbe34d557a9d1e 127 SUPERFAMILY SSF53062 1 122 1.17E-22 T 10-11-2016 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 A4G23_RS00885 087d3534de5f6b1576cbe34d557a9d1e 127 Pfam PF03610 PTS system fructose IIA component 1 112 2.2E-19 T 10-11-2016 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 A4G23_RS00885 087d3534de5f6b1576cbe34d557a9d1e 127 Gene3D G3DSA:3.40.50.510 1 126 3.3E-35 T 10-11-2016 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 A4G23_RS08780 9a6611b1259a2d496e6039c1557d41b2 215 SUPERFAMILY SSF53597 37 213 7.29E-24 T 10-11-2016 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 A4G23_RS08780 9a6611b1259a2d496e6039c1557d41b2 215 Pfam PF01872 RibD C-terminal domain 53 189 2.2E-11 T 10-11-2016 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 A4G23_RS08780 9a6611b1259a2d496e6039c1557d41b2 215 Gene3D G3DSA:3.40.430.10 9 214 1.3E-37 T 10-11-2016 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 A4G23_RS12735 4f24bfed10eafb58e23dd789198d583d 701 SUPERFAMILY SSF56235 67 195 3.09E-13 T 10-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal A4G23_RS12735 4f24bfed10eafb58e23dd789198d583d 701 Gene3D G3DSA:3.60.20.10 69 195 7.1E-11 T 10-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal A4G23_RS12735 4f24bfed10eafb58e23dd789198d583d 701 Gene3D G3DSA:3.40.50.620 444 445 3.6E-9 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS12735 4f24bfed10eafb58e23dd789198d583d 701 Gene3D G3DSA:3.40.50.620 261 377 3.6E-9 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS12735 4f24bfed10eafb58e23dd789198d583d 701 Gene3D G3DSA:3.40.50.620 207 229 3.6E-9 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS12735 4f24bfed10eafb58e23dd789198d583d 701 Gene3D G3DSA:3.40.50.620 523 668 3.6E-9 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS12735 4f24bfed10eafb58e23dd789198d583d 701 SUPERFAMILY SSF52402 520 597 4.26E-8 T 10-11-2016 A4G23_RS12735 4f24bfed10eafb58e23dd789198d583d 701 SUPERFAMILY SSF52402 263 403 4.26E-8 T 10-11-2016 A4G23_RS12735 4f24bfed10eafb58e23dd789198d583d 701 Pfam PF00733 Asparagine synthase 264 667 8.8E-11 T 10-11-2016 IPR001962 Asparagine synthase GO:0004066|GO:0006529 A4G23_RS20715 8d96c87006ea9e5a90887a6e89e09d7c 472 Gene3D G3DSA:3.50.50.60 31 132 3.5E-31 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS20715 8d96c87006ea9e5a90887a6e89e09d7c 472 Gene3D G3DSA:3.50.50.60 371 422 3.5E-31 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS20715 8d96c87006ea9e5a90887a6e89e09d7c 472 Gene3D G3DSA:3.50.50.60 190 266 3.5E-31 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS20715 8d96c87006ea9e5a90887a6e89e09d7c 472 SUPERFAMILY SSF51905 192 322 6.74E-35 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS20715 8d96c87006ea9e5a90887a6e89e09d7c 472 SUPERFAMILY SSF51905 16 135 6.74E-35 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS20715 8d96c87006ea9e5a90887a6e89e09d7c 472 Gene3D G3DSA:3.30.9.10 136 189 2.2E-7 T 10-11-2016 A4G23_RS20715 8d96c87006ea9e5a90887a6e89e09d7c 472 Gene3D G3DSA:3.30.9.10 267 367 2.2E-7 T 10-11-2016 A4G23_RS20715 8d96c87006ea9e5a90887a6e89e09d7c 472 Pfam PF01266 FAD dependent oxidoreductase 42 405 4.6E-45 T 10-11-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A4G23_RS25815 395f48790ee027c3dd6c71b46cf2e258 357 Pfam PF02310 B12 binding domain 92 197 4.8E-16 T 10-11-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A4G23_RS25815 395f48790ee027c3dd6c71b46cf2e258 357 SUPERFAMILY SSF52242 86 206 1.46E-18 T 10-11-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A4G23_RS25815 395f48790ee027c3dd6c71b46cf2e258 357 Pfam PF02607 B12 binding domain 5 76 1.5E-10 T 10-11-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4G23_RS25815 395f48790ee027c3dd6c71b46cf2e258 357 Gene3D G3DSA:3.40.50.280 88 205 3.1E-18 T 10-11-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A4G23_RS17365 8b7b6123093fee07aef6a5e175ed5577 252 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 25 244 2.5E-79 T 10-11-2016 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4G23_RS17365 8b7b6123093fee07aef6a5e175ed5577 252 Gene3D G3DSA:3.10.20.30 18 122 1.1E-39 T 10-11-2016 IPR012675 Beta-grasp domain A4G23_RS17365 8b7b6123093fee07aef6a5e175ed5577 252 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 164 175 - T 10-11-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4G23_RS17365 8b7b6123093fee07aef6a5e175ed5577 252 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 22 127 1.2E-36 T 10-11-2016 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4G23_RS17365 8b7b6123093fee07aef6a5e175ed5577 252 SUPERFAMILY SSF54292 18 122 2.27E-29 T 10-11-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A4G23_RS17365 8b7b6123093fee07aef6a5e175ed5577 252 Gene3D G3DSA:1.10.1060.10 123 250 1.0E-39 T 10-11-2016 A4G23_RS17365 8b7b6123093fee07aef6a5e175ed5577 252 SUPERFAMILY SSF46548 123 249 6.45E-33 T 10-11-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 A4G23_RS17365 8b7b6123093fee07aef6a5e175ed5577 252 Pfam PF13183 4Fe-4S dicluster domain 162 234 7.4E-12 T 10-11-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4G23_RS05730 892a46912ca313d52a8024e13bbf5e8c 331 Pfam PF03741 Integral membrane protein TerC family 68 274 1.5E-53 T 10-11-2016 IPR005496 Integral membrane protein TerC GO:0016021 A4G23_RS05730 892a46912ca313d52a8024e13bbf5e8c 331 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 4 311 2.7E-111 T 10-11-2016 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 A4G23_RS16660 7155c0ef022608f8c0aee0d961b4e2ee 107 Gene3D G3DSA:2.30.30.30 1 95 4.3E-26 T 10-11-2016 IPR014722 Ribosomal protein L2 domain 2 A4G23_RS16660 7155c0ef022608f8c0aee0d961b4e2ee 107 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 107 1.6E-24 T 10-11-2016 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS16660 7155c0ef022608f8c0aee0d961b4e2ee 107 Pfam PF00467 KOW motif 5 36 2.9E-7 T 10-11-2016 IPR005824 KOW A4G23_RS16660 7155c0ef022608f8c0aee0d961b4e2ee 107 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 1 107 6.0E-36 T 10-11-2016 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS16660 7155c0ef022608f8c0aee0d961b4e2ee 107 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 1 101 21.656 T 10-11-2016 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS16660 7155c0ef022608f8c0aee0d961b4e2ee 107 ProSitePatterns PS01108 Ribosomal protein L24 signature. 6 23 - T 10-11-2016 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS16660 7155c0ef022608f8c0aee0d961b4e2ee 107 SMART SM00739 2 29 2.1E-5 T 10-11-2016 IPR005824 KOW A4G23_RS16660 7155c0ef022608f8c0aee0d961b4e2ee 107 SUPERFAMILY SSF50104 1 105 6.39E-32 T 10-11-2016 IPR008991 Translation protein SH3-like domain A4G23_RS17805 45d3657411f5b2441d9d9afb6e707d93 305 SUPERFAMILY SSF100950 64 224 9.73E-29 T 10-11-2016 A4G23_RS17805 45d3657411f5b2441d9d9afb6e707d93 305 Pfam PF00455 DeoR C terminal sensor domain 64 220 2.6E-49 T 10-11-2016 IPR014036 DeoR C-terminal sensor domain A4G23_RS17805 45d3657411f5b2441d9d9afb6e707d93 305 Gene3D G3DSA:3.40.50.1360 65 211 2.6E-12 T 10-11-2016 A4G23_RS17805 45d3657411f5b2441d9d9afb6e707d93 305 Gene3D G3DSA:1.10.10.10 2 44 5.7E-7 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS17805 45d3657411f5b2441d9d9afb6e707d93 305 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 12 26 5.3E-8 T 10-11-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A4G23_RS17805 45d3657411f5b2441d9d9afb6e707d93 305 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 26 44 5.3E-8 T 10-11-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A4G23_RS17805 45d3657411f5b2441d9d9afb6e707d93 305 SMART SM00420 1 46 2.6E-6 T 10-11-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A4G23_RS17805 45d3657411f5b2441d9d9afb6e707d93 305 SMART SM01134 61 222 6.2E-64 T 10-11-2016 A4G23_RS17805 45d3657411f5b2441d9d9afb6e707d93 305 SUPERFAMILY SSF46785 3 47 3.37E-10 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS17805 45d3657411f5b2441d9d9afb6e707d93 305 Pfam PF08220 DeoR-like helix-turn-helix domain 1 46 3.6E-11 T 10-11-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A4G23_RS24545 d63d78aadab61e7eedb0f894a035c410 607 ProSitePatterns PS00455 Putative AMP-binding domain signature. 184 195 - T 10-11-2016 IPR020845 AMP-binding, conserved site A4G23_RS24545 d63d78aadab61e7eedb0f894a035c410 607 Pfam PF00501 AMP-binding enzyme 24 477 7.4E-86 T 10-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A4G23_RS24545 d63d78aadab61e7eedb0f894a035c410 607 Gene3D G3DSA:3.30.300.30 475 598 4.7E-6 T 10-11-2016 A4G23_RS24545 d63d78aadab61e7eedb0f894a035c410 607 Gene3D G3DSA:3.40.50.980 20 189 7.2E-31 T 10-11-2016 A4G23_RS24545 d63d78aadab61e7eedb0f894a035c410 607 SUPERFAMILY SSF56801 348 606 3.01E-108 T 10-11-2016 A4G23_RS24545 d63d78aadab61e7eedb0f894a035c410 607 SUPERFAMILY SSF56801 18 294 3.01E-108 T 10-11-2016 A4G23_RS24545 d63d78aadab61e7eedb0f894a035c410 607 Gene3D G3DSA:2.30.38.10 409 471 7.4E-15 T 10-11-2016 A4G23_RS24545 d63d78aadab61e7eedb0f894a035c410 607 Gene3D G3DSA:3.40.50.980 190 289 1.1E-25 T 10-11-2016 A4G23_RS24545 d63d78aadab61e7eedb0f894a035c410 607 Gene3D G3DSA:3.40.50.980 345 408 1.1E-25 T 10-11-2016 A4G23_RS14980 7039db4548ac4f462c12ae3ace1ad204 403 Pfam PF13177 DNA polymerase III, delta subunit 41 190 6.7E-35 T 10-11-2016 A4G23_RS14980 7039db4548ac4f462c12ae3ace1ad204 403 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 40 225 4.9E-54 T 10-11-2016 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4G23_RS14980 7039db4548ac4f462c12ae3ace1ad204 403 Gene3D G3DSA:3.40.50.300 4 190 3.4E-51 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS14980 7039db4548ac4f462c12ae3ace1ad204 403 SUPERFAMILY SSF52540 4 229 6.25E-42 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS09240 5817ab2134e4b01a1ae730ceb8ddc147 365 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 13 344 5.0E-130 T 10-11-2016 IPR019949 Luciferase family oxidoreductase, group 1 A4G23_RS09240 5817ab2134e4b01a1ae730ceb8ddc147 365 Pfam PF00296 Luciferase-like monooxygenase 15 319 2.8E-40 T 10-11-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4G23_RS09240 5817ab2134e4b01a1ae730ceb8ddc147 365 SUPERFAMILY SSF51679 12 343 2.36E-80 T 10-11-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4G23_RS09240 5817ab2134e4b01a1ae730ceb8ddc147 365 Gene3D G3DSA:3.20.20.30 12 343 1.5E-93 T 10-11-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4G23_RS16130 ecbd4c53e35d65648206c86bcf660d12 411 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 122 407 3.9E-53 T 10-11-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 A4G23_RS16130 ecbd4c53e35d65648206c86bcf660d12 411 Pfam PF09298 Fumarylacetoacetase N-terminal 21 116 3.9E-21 T 10-11-2016 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 A4G23_RS16130 ecbd4c53e35d65648206c86bcf660d12 411 Gene3D G3DSA:2.30.30.230 10 118 1.3E-29 T 10-11-2016 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 A4G23_RS16130 ecbd4c53e35d65648206c86bcf660d12 411 SUPERFAMILY SSF56529 118 409 1.7E-88 T 10-11-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 A4G23_RS16130 ecbd4c53e35d65648206c86bcf660d12 411 Gene3D G3DSA:3.90.850.10 119 404 1.2E-105 T 10-11-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 A4G23_RS16130 ecbd4c53e35d65648206c86bcf660d12 411 TIGRFAM TIGR01266 fum_ac_acetase: fumarylacetoacetase 11 411 2.2E-127 T 10-11-2016 IPR005959 Fumarylacetoacetase GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 A4G23_RS16130 ecbd4c53e35d65648206c86bcf660d12 411 SUPERFAMILY SSF63433 8 116 1.15E-26 T 10-11-2016 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 A4G23_RS08825 cbef88ae3ed4bc0c942d708f1dbac3ba 633 Gene3D G3DSA:3.40.50.1700 444 632 1.8E-20 T 10-11-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 A4G23_RS08825 cbef88ae3ed4bc0c942d708f1dbac3ba 633 SUPERFAMILY SSF52279 457 633 9.15E-19 T 10-11-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 A4G23_RS08825 cbef88ae3ed4bc0c942d708f1dbac3ba 633 SUPERFAMILY SSF51445 67 453 1.37E-106 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS08825 cbef88ae3ed4bc0c942d708f1dbac3ba 633 Gene3D G3DSA:3.20.20.300 115 443 8.3E-116 T 10-11-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4G23_RS08825 cbef88ae3ed4bc0c942d708f1dbac3ba 633 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 339 356 - T 10-11-2016 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 A4G23_RS08825 cbef88ae3ed4bc0c942d708f1dbac3ba 633 PRINTS PR00133 Glycosyl hydrolase family 3 signature 184 203 4.7E-8 T 10-11-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4G23_RS08825 cbef88ae3ed4bc0c942d708f1dbac3ba 633 PRINTS PR00133 Glycosyl hydrolase family 3 signature 262 278 4.7E-8 T 10-11-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4G23_RS08825 cbef88ae3ed4bc0c942d708f1dbac3ba 633 PRINTS PR00133 Glycosyl hydrolase family 3 signature 339 357 4.7E-8 T 10-11-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4G23_RS08825 cbef88ae3ed4bc0c942d708f1dbac3ba 633 PRINTS PR00133 Glycosyl hydrolase family 3 signature 158 174 4.7E-8 T 10-11-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4G23_RS08825 cbef88ae3ed4bc0c942d708f1dbac3ba 633 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 457 633 1.8E-18 T 10-11-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 A4G23_RS08825 cbef88ae3ed4bc0c942d708f1dbac3ba 633 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 79 418 3.6E-114 T 10-11-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4G23_RS13610 5121529ecfbb40acdfcbf3d502eca0c5 148 Gene3D G3DSA:3.10.430.100 62 147 9.9E-31 T 10-11-2016 IPR020069 Ribosomal protein L9, C-terminal A4G23_RS13610 5121529ecfbb40acdfcbf3d502eca0c5 148 Pfam PF03948 Ribosomal protein L9, C-terminal domain 63 147 3.6E-29 T 10-11-2016 IPR020069 Ribosomal protein L9, C-terminal A4G23_RS13610 5121529ecfbb40acdfcbf3d502eca0c5 148 SUPERFAMILY SSF55658 1 56 4.19E-17 T 10-11-2016 IPR009027 Ribosomal protein L9/RNase H1, N-terminal A4G23_RS13610 5121529ecfbb40acdfcbf3d502eca0c5 148 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 45 6.6E-21 T 10-11-2016 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS13610 5121529ecfbb40acdfcbf3d502eca0c5 148 Gene3D G3DSA:3.40.5.10 1 51 8.1E-22 T 10-11-2016 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS13610 5121529ecfbb40acdfcbf3d502eca0c5 148 SUPERFAMILY SSF55653 59 147 4.32E-25 T 10-11-2016 IPR020069 Ribosomal protein L9, C-terminal A4G23_RS13610 5121529ecfbb40acdfcbf3d502eca0c5 148 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 148 25.632 T 10-11-2016 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS13610 5121529ecfbb40acdfcbf3d502eca0c5 148 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 147 1.0E-40 T 10-11-2016 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS13610 5121529ecfbb40acdfcbf3d502eca0c5 148 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 10-11-2016 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS03630 3e725180ec9b7a2a3914381365c9624c 157 SUPERFAMILY SSF53098 7 141 3.34E-34 T 10-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 A4G23_RS03630 3e725180ec9b7a2a3914381365c9624c 157 SMART SM00732 7 108 1.4E-31 T 10-11-2016 IPR006641 YqgF/RNase H-like domain GO:0006139 A4G23_RS03630 3e725180ec9b7a2a3914381365c9624c 157 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 10 140 6.2E-30 T 10-11-2016 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 A4G23_RS03630 3e725180ec9b7a2a3914381365c9624c 157 Pfam PF03652 Holliday junction resolvase 8 140 4.5E-41 T 10-11-2016 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 A4G23_RS03630 3e725180ec9b7a2a3914381365c9624c 157 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 7 143 22.504 T 10-11-2016 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 A4G23_RS03630 3e725180ec9b7a2a3914381365c9624c 157 Gene3D G3DSA:3.30.420.140 6 145 2.0E-45 T 10-11-2016 IPR006641 YqgF/RNase H-like domain GO:0006139 A4G23_RS20435 e453a9f166db007c39b5185b55529a05 93 Gene3D G3DSA:3.30.70.100 6 93 4.3E-28 T 10-11-2016 A4G23_RS20435 e453a9f166db007c39b5185b55529a05 93 SUPERFAMILY SSF54975 4 93 9.81E-25 T 10-11-2016 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A4G23_RS20435 e453a9f166db007c39b5185b55529a05 93 ProSitePatterns PS00150 Acylphosphatase signature 1. 11 21 - T 10-11-2016 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A4G23_RS20435 e453a9f166db007c39b5185b55529a05 93 Pfam PF00708 Acylphosphatase 5 93 3.5E-22 T 10-11-2016 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A4G23_RS04855 22d099eea8cfafd9dbf6865832e3bf4e 361 SUPERFAMILY SSF55021 294 353 8.74E-5 T 10-11-2016 A4G23_RS04855 22d099eea8cfafd9dbf6865832e3bf4e 361 SUPERFAMILY SSF48179 165 251 4.19E-21 T 10-11-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A4G23_RS04855 22d099eea8cfafd9dbf6865832e3bf4e 361 Gene3D G3DSA:3.40.50.720 4 171 3.2E-24 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS04855 22d099eea8cfafd9dbf6865832e3bf4e 361 Pfam PF02153 Prephenate dehydrogenase 17 250 1.2E-55 T 10-11-2016 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 A4G23_RS04855 22d099eea8cfafd9dbf6865832e3bf4e 361 SUPERFAMILY SSF51735 5 158 6.78E-25 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS10735 7e315741578f40fa74384ef806a7ade2 293 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 10-11-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4G23_RS10735 7e315741578f40fa74384ef806a7ade2 293 SUPERFAMILY SSF51735 5 267 1.37E-58 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS10735 7e315741578f40fa74384ef806a7ade2 293 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 3.4E-8 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS10735 7e315741578f40fa74384ef806a7ade2 293 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 3.4E-8 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS10735 7e315741578f40fa74384ef806a7ade2 293 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 3.4E-8 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS10735 7e315741578f40fa74384ef806a7ade2 293 Pfam PF00106 short chain dehydrogenase 9 197 2.4E-45 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS10735 7e315741578f40fa74384ef806a7ade2 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 2.6E-18 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS10735 7e315741578f40fa74384ef806a7ade2 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 2.6E-18 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS10735 7e315741578f40fa74384ef806a7ade2 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 2.6E-18 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS10735 7e315741578f40fa74384ef806a7ade2 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 2.6E-18 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS10735 7e315741578f40fa74384ef806a7ade2 293 Gene3D G3DSA:3.40.50.720 8 232 2.2E-55 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS10735 7e315741578f40fa74384ef806a7ade2 293 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 188 6.7E-5 T 10-11-2016 A4G23_RS22810 1a379a34318433aeb1f62c3e5d44eb67 117 Pfam PF09707 CRISPR-associated protein (Cas_Cas2CT1978) 2 85 9.6E-32 T 10-11-2016 IPR010152 CRISPR-associated protein Cas2 subtype A4G23_RS22810 1a379a34318433aeb1f62c3e5d44eb67 117 TIGRFAM TIGR01873 cas_CT1978: CRISPR-associated endoribonuclease Cas2, subtype I-E/ECOLI 3 85 8.3E-17 T 10-11-2016 IPR010152 CRISPR-associated protein Cas2 subtype A4G23_RS26005 1976dee0c31bf66e43c56b7225908054 608 Pfam PF00733 Asparagine synthase 240 598 1.1E-79 T 10-11-2016 IPR001962 Asparagine synthase GO:0004066|GO:0006529 A4G23_RS26005 1976dee0c31bf66e43c56b7225908054 608 SUPERFAMILY SSF52402 453 570 1.18E-57 T 10-11-2016 A4G23_RS26005 1976dee0c31bf66e43c56b7225908054 608 SUPERFAMILY SSF52402 219 397 1.18E-57 T 10-11-2016 A4G23_RS26005 1976dee0c31bf66e43c56b7225908054 608 Gene3D G3DSA:3.40.50.620 223 395 3.1E-71 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS26005 1976dee0c31bf66e43c56b7225908054 608 Gene3D G3DSA:3.40.50.620 451 599 3.1E-71 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS26005 1976dee0c31bf66e43c56b7225908054 608 Pfam PF13537 Glutamine amidotransferase domain 48 168 9.4E-45 T 10-11-2016 IPR017932 Glutamine amidotransferase type 2 domain A4G23_RS26005 1976dee0c31bf66e43c56b7225908054 608 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 536 3.6E-140 T 10-11-2016 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 A4G23_RS26005 1976dee0c31bf66e43c56b7225908054 608 Gene3D G3DSA:3.60.20.10 1 222 2.5E-74 T 10-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal A4G23_RS26005 1976dee0c31bf66e43c56b7225908054 608 PIRSF PIRSF001589 1 606 6.6E-138 T 10-11-2016 A4G23_RS26005 1976dee0c31bf66e43c56b7225908054 608 SUPERFAMILY SSF56235 1 224 7.72E-65 T 10-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal A4G23_RS25315 2425dce2a9a8ed85ead3c2e87834be00 594 Pfam PF00005 ABC transporter 369 518 8.3E-32 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS25315 2425dce2a9a8ed85ead3c2e87834be00 594 Gene3D G3DSA:3.40.50.300 351 578 1.1E-75 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS25315 2425dce2a9a8ed85ead3c2e87834be00 594 SMART SM00382 378 564 1.7E-16 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS25315 2425dce2a9a8ed85ead3c2e87834be00 594 Pfam PF00664 ABC transporter transmembrane region 30 296 2.2E-36 T 10-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A4G23_RS25315 2425dce2a9a8ed85ead3c2e87834be00 594 SUPERFAMILY SSF52540 348 586 5.22E-81 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS25315 2425dce2a9a8ed85ead3c2e87834be00 594 Gene3D G3DSA:1.20.1560.10 18 335 4.1E-72 T 10-11-2016 A4G23_RS25315 2425dce2a9a8ed85ead3c2e87834be00 594 SUPERFAMILY SSF90123 17 326 8.89E-64 T 10-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A4G23_RS25315 2425dce2a9a8ed85ead3c2e87834be00 594 ProSitePatterns PS00211 ABC transporters family signature. 490 504 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS24780 7e1d8b8f21a41ffc6cbc76db239daf4e 346 SUPERFAMILY SSF47413 9 66 3.22E-16 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS24780 7e1d8b8f21a41ffc6cbc76db239daf4e 346 Pfam PF13377 Periplasmic binding protein-like domain 185 345 3.6E-34 T 10-11-2016 A4G23_RS24780 7e1d8b8f21a41ffc6cbc76db239daf4e 346 SMART SM00354 9 79 2.4E-18 T 10-11-2016 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4G23_RS24780 7e1d8b8f21a41ffc6cbc76db239daf4e 346 Gene3D G3DSA:1.10.260.40 9 59 1.4E-21 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS24780 7e1d8b8f21a41ffc6cbc76db239daf4e 346 Gene3D G3DSA:3.40.50.2300 60 189 6.3E-27 T 10-11-2016 A4G23_RS24780 7e1d8b8f21a41ffc6cbc76db239daf4e 346 Pfam PF00356 Bacterial regulatory proteins, lacI family 11 56 4.6E-15 T 10-11-2016 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4G23_RS24780 7e1d8b8f21a41ffc6cbc76db239daf4e 346 SUPERFAMILY SSF53822 82 345 4.12E-61 T 10-11-2016 IPR028082 Periplasmic binding protein-like I A4G23_RS24780 7e1d8b8f21a41ffc6cbc76db239daf4e 346 Gene3D G3DSA:3.40.50.2300 190 323 7.8E-51 T 10-11-2016 A4G23_RS19230 e83c32eccc4e222d0199985df8b043c0 243 SUPERFAMILY SSF53335 75 224 2.9E-20 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS19230 e83c32eccc4e222d0199985df8b043c0 243 Gene3D G3DSA:3.40.50.150 77 210 1.9E-20 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS13350 0f0872ea84b5b0b9be2136e2d064320b 682 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 40 - T 10-11-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 A4G23_RS13350 0f0872ea84b5b0b9be2136e2d064320b 682 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 134 146 - T 10-11-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 A4G23_RS13350 0f0872ea84b5b0b9be2136e2d064320b 682 SMART SM00220 11 277 1.3E-68 T 10-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4G23_RS13350 0f0872ea84b5b0b9be2136e2d064320b 682 Pfam PF00069 Protein kinase domain 11 264 5.3E-50 T 10-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4G23_RS13350 0f0872ea84b5b0b9be2136e2d064320b 682 SMART SM00740 581 645 1.7E-5 T 10-11-2016 IPR005543 PASTA domain A4G23_RS13350 0f0872ea84b5b0b9be2136e2d064320b 682 SMART SM00740 448 513 2.8E-11 T 10-11-2016 IPR005543 PASTA domain A4G23_RS13350 0f0872ea84b5b0b9be2136e2d064320b 682 SMART SM00740 379 447 9.0E-4 T 10-11-2016 IPR005543 PASTA domain A4G23_RS13350 0f0872ea84b5b0b9be2136e2d064320b 682 SMART SM00740 514 578 3.9E-12 T 10-11-2016 IPR005543 PASTA domain A4G23_RS13350 0f0872ea84b5b0b9be2136e2d064320b 682 Pfam PF03793 PASTA domain 585 642 7.9E-9 T 10-11-2016 IPR005543 PASTA domain A4G23_RS13350 0f0872ea84b5b0b9be2136e2d064320b 682 Pfam PF03793 PASTA domain 517 578 4.3E-12 T 10-11-2016 IPR005543 PASTA domain A4G23_RS13350 0f0872ea84b5b0b9be2136e2d064320b 682 Pfam PF03793 PASTA domain 383 446 2.8E-10 T 10-11-2016 IPR005543 PASTA domain A4G23_RS13350 0f0872ea84b5b0b9be2136e2d064320b 682 Pfam PF03793 PASTA domain 452 512 5.7E-11 T 10-11-2016 IPR005543 PASTA domain A4G23_RS13350 0f0872ea84b5b0b9be2136e2d064320b 682 Gene3D G3DSA:1.10.510.10 98 273 4.2E-49 T 10-11-2016 A4G23_RS13350 0f0872ea84b5b0b9be2136e2d064320b 682 SUPERFAMILY SSF56112 7 274 3.37E-78 T 10-11-2016 IPR011009 Protein kinase-like domain A4G23_RS13350 0f0872ea84b5b0b9be2136e2d064320b 682 Gene3D G3DSA:3.30.200.20 4 94 4.7E-30 T 10-11-2016 A4G23_RS17665 0e2eb9dc64f899c19495666befd327b6 550 PRINTS PR00344 Bacterial sensor protein C-terminal signature 426 440 7.6E-15 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS17665 0e2eb9dc64f899c19495666befd327b6 550 PRINTS PR00344 Bacterial sensor protein C-terminal signature 485 498 7.6E-15 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS17665 0e2eb9dc64f899c19495666befd327b6 550 PRINTS PR00344 Bacterial sensor protein C-terminal signature 444 454 7.6E-15 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS17665 0e2eb9dc64f899c19495666befd327b6 550 PRINTS PR00344 Bacterial sensor protein C-terminal signature 460 478 7.6E-15 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS17665 0e2eb9dc64f899c19495666befd327b6 550 SMART SM00388 284 351 3.0E-16 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS17665 0e2eb9dc64f899c19495666befd327b6 550 SMART SM00387 391 501 6.5E-33 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS17665 0e2eb9dc64f899c19495666befd327b6 550 SUPERFAMILY SSF47384 269 351 4.32E-15 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS17665 0e2eb9dc64f899c19495666befd327b6 550 SUPERFAMILY SSF55874 341 499 1.96E-34 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS17665 0e2eb9dc64f899c19495666befd327b6 550 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 392 499 8.4E-22 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS17665 0e2eb9dc64f899c19495666befd327b6 550 SMART SM00304 224 276 1.9E-14 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS17665 0e2eb9dc64f899c19495666befd327b6 550 Gene3D G3DSA:1.10.287.130 276 338 6.8E-15 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS17665 0e2eb9dc64f899c19495666befd327b6 550 Pfam PF00672 HAMP domain 205 272 1.4E-15 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS17665 0e2eb9dc64f899c19495666befd327b6 550 Gene3D G3DSA:3.30.565.10 339 502 1.9E-38 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS17665 0e2eb9dc64f899c19495666befd327b6 550 Pfam PF00512 His Kinase A (phospho-acceptor) domain 285 351 2.0E-14 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS17665 0e2eb9dc64f899c19495666befd327b6 550 SUPERFAMILY SSF158472 226 273 3.79E-8 T 10-11-2016 A4G23_RS03570 9491f36570d33fb7a73d9e747d2d1bfc 191 Gene3D G3DSA:3.40.50.2020 14 176 8.8E-50 T 10-11-2016 IPR029057 Phosphoribosyltransferase-like A4G23_RS03570 9491f36570d33fb7a73d9e747d2d1bfc 191 Pfam PF00156 Phosphoribosyl transferase domain 12 152 3.6E-20 T 10-11-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 A4G23_RS03570 9491f36570d33fb7a73d9e747d2d1bfc 191 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 9 182 37.1 T 10-11-2016 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 A4G23_RS03570 9491f36570d33fb7a73d9e747d2d1bfc 191 SUPERFAMILY SSF53271 11 178 3.93E-41 T 10-11-2016 IPR029057 Phosphoribosyltransferase-like A4G23_RS19905 63158095ae7e13c373f0d2354185e69b 2087 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1562 1603 6.7E-8 T 10-11-2016 IPR006530 YD repeat A4G23_RS19905 63158095ae7e13c373f0d2354185e69b 2087 ProDom PD039135 WALL-ASSOCIATED REPEAT PROTEIN CELL WALL HYDROLASE PRECURSOR SIGNAL TRANSMEMBRANE RETICULOCYTE 92 287 2.0E-5 T 10-11-2016 A4G23_RS19905 63158095ae7e13c373f0d2354185e69b 2087 Pfam PF05593 RHS Repeat 1541 1578 1.1E-5 T 10-11-2016 IPR031325 RHS repeat A4G23_RS19905 63158095ae7e13c373f0d2354185e69b 2087 Pfam PF05593 RHS Repeat 1562 1595 1.9E-6 T 10-11-2016 IPR031325 RHS repeat A4G23_RS19905 63158095ae7e13c373f0d2354185e69b 2087 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1901 1973 5.4E-13 T 10-11-2016 IPR022385 Rhs repeat-associated core GO:0097264 A4G23_RS19040 9c48ae56e3631a21658724168c9b40ed 85 Pfam PF02467 Transcription factor WhiB 3 71 1.6E-27 T 10-11-2016 IPR003482 Transcription factor WhiB A4G23_RS19040 9c48ae56e3631a21658724168c9b40ed 85 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 76 19.15 T 10-11-2016 IPR003482 Transcription factor WhiB A4G23_RS21865 7f599456fdf2447c4bb73df72adadbb2 421 SUPERFAMILY SSF48264 29 418 4.58E-51 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS21865 7f599456fdf2447c4bb73df72adadbb2 421 Gene3D G3DSA:1.10.630.10 23 418 1.6E-73 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS21865 7f599456fdf2447c4bb73df72adadbb2 421 PRINTS PR00359 B-class P450 signature 157 173 2.2E-12 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS21865 7f599456fdf2447c4bb73df72adadbb2 421 PRINTS PR00359 B-class P450 signature 212 234 2.2E-12 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS21865 7f599456fdf2447c4bb73df72adadbb2 421 PRINTS PR00359 B-class P450 signature 308 335 2.2E-12 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS03535 5d511ebcead05efd2fc725ebae79474f 277 TIGRFAM TIGR02127 pyrF_sub2: orotidine 5'-phosphate decarboxylase 4 262 5.2E-83 T 10-11-2016 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686 A4G23_RS03535 5d511ebcead05efd2fc725ebae79474f 277 Hamap MF_01215 Orotidine 5'-phosphate decarboxylase [pyrF]. 2 277 33.792 T 10-11-2016 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686 A4G23_RS03535 5d511ebcead05efd2fc725ebae79474f 277 SUPERFAMILY SSF51366 4 267 4.33E-61 T 10-11-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 A4G23_RS03535 5d511ebcead05efd2fc725ebae79474f 277 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 17 261 8.3E-37 T 10-11-2016 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 A4G23_RS03535 5d511ebcead05efd2fc725ebae79474f 277 SMART SM00934 17 263 2.2E-33 T 10-11-2016 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 A4G23_RS03535 5d511ebcead05efd2fc725ebae79474f 277 Gene3D G3DSA:3.20.20.70 6 268 4.1E-58 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS03535 5d511ebcead05efd2fc725ebae79474f 277 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 91 104 - T 10-11-2016 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 A4G23_RS19235 2702b4ce0fb607a5f598c6894d03ae18 213 SUPERFAMILY SSF55729 101 207 7.75E-14 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS19235 2702b4ce0fb607a5f598c6894d03ae18 213 Gene3D G3DSA:3.40.630.30 110 201 2.0E-11 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS02375 5db5329c26030a73ca0bc670e0edacc9 290 Gene3D G3DSA:3.30.160.60 253 286 7.9E-5 T 10-11-2016 IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain GO:0003676 A4G23_RS02375 5db5329c26030a73ca0bc670e0edacc9 290 Pfam PF02618 YceG-like family 62 279 5.4E-57 T 10-11-2016 IPR003770 Uncharacterised protein family UPF0755, YceG-like A4G23_RS02375 5db5329c26030a73ca0bc670e0edacc9 290 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 110 283 1.3E-39 T 10-11-2016 IPR003770 Uncharacterised protein family UPF0755, YceG-like A4G23_RS17255 12db4ff361ffc4680a6df115eb7e6c96 329 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 7 147 1.8E-31 T 10-11-2016 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 A4G23_RS17255 12db4ff361ffc4680a6df115eb7e6c96 329 Gene3D G3DSA:3.90.110.10 156 326 7.0E-78 T 10-11-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 A4G23_RS17255 12db4ff361ffc4680a6df115eb7e6c96 329 SUPERFAMILY SSF51735 4 156 1.98E-41 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS17255 12db4ff361ffc4680a6df115eb7e6c96 329 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 157 321 1.8E-33 T 10-11-2016 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 A4G23_RS17255 12db4ff361ffc4680a6df115eb7e6c96 329 Hamap MF_01517 Malate dehydrogenase [mdh]. 2 327 57.619 T 10-11-2016 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 A4G23_RS17255 12db4ff361ffc4680a6df115eb7e6c96 329 PIRSF PIRSF000102 2 326 9.8E-62 T 10-11-2016 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 A4G23_RS17255 12db4ff361ffc4680a6df115eb7e6c96 329 Gene3D G3DSA:3.40.50.720 5 154 1.1E-51 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS17255 12db4ff361ffc4680a6df115eb7e6c96 329 TIGRFAM TIGR01759 MalateDH-SF1: malate dehydrogenase 4 323 2.9E-148 T 10-11-2016 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 A4G23_RS17255 12db4ff361ffc4680a6df115eb7e6c96 329 ProSitePatterns PS00068 Malate dehydrogenase active site signature. 156 168 - T 10-11-2016 IPR001252 Malate dehydrogenase, active site GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383|Reactome: R-HSA-70263 A4G23_RS17255 12db4ff361ffc4680a6df115eb7e6c96 329 SUPERFAMILY SSF56327 157 324 7.41E-63 T 10-11-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 A4G23_RS02860 2e7b068115a49ce0135be7e6e54722be 669 SMART SM00331 314 526 4.3E-23 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS02860 2e7b068115a49ce0135be7e6e54722be 669 Gene3D G3DSA:3.30.450.40 127 300 2.6E-9 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS02860 2e7b068115a49ce0135be7e6e54722be 669 Pfam PF08447 PAS fold 29 116 4.1E-13 T 10-11-2016 IPR013655 PAS fold-3 GO:0005515 A4G23_RS02860 2e7b068115a49ce0135be7e6e54722be 669 SUPERFAMILY SSF55785 18 121 1.06E-9 T 10-11-2016 IPR000014 PAS domain A4G23_RS02860 2e7b068115a49ce0135be7e6e54722be 669 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 344 526 3.1E-45 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS02860 2e7b068115a49ce0135be7e6e54722be 669 SUPERFAMILY SSF55874 563 644 1.34E-7 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS02860 2e7b068115a49ce0135be7e6e54722be 669 SUPERFAMILY SSF55781 159 299 1.11E-11 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS02860 2e7b068115a49ce0135be7e6e54722be 669 SUPERFAMILY SSF81606 331 525 3.92E-7 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS02860 2e7b068115a49ce0135be7e6e54722be 669 Gene3D G3DSA:3.30.565.10 549 631 2.0E-4 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS02860 2e7b068115a49ce0135be7e6e54722be 669 Pfam PF13581 Histidine kinase-like ATPase domain 541 638 1.6E-9 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS02860 2e7b068115a49ce0135be7e6e54722be 669 Gene3D G3DSA:3.30.450.20 20 118 3.7E-11 T 10-11-2016 A4G23_RS02860 2e7b068115a49ce0135be7e6e54722be 669 SMART SM00065 144 296 9.5E-5 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS02860 2e7b068115a49ce0135be7e6e54722be 669 SMART SM00086 80 122 1.3E-6 T 10-11-2016 IPR001610 PAC motif A4G23_RS06565 5bd15228a1112eceaf075bc64a7fe483 132 PIRSF PIRSF017385 1 131 1.4E-48 T 10-11-2016 IPR021050 Cytochrome c oxidase subunit IV, actinobacteria GO:0004129|GO:0016021|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 A4G23_RS06565 5bd15228a1112eceaf075bc64a7fe483 132 Pfam PF12270 Cytochrome c oxidase subunit IV 2 130 6.0E-53 T 10-11-2016 IPR021050 Cytochrome c oxidase subunit IV, actinobacteria GO:0004129|GO:0016021|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 A4G23_RS07455 b61f4ba21777800908ab8b77443978e2 226 Pfam PF00196 Bacterial regulatory proteins, luxR family 160 214 1.5E-19 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS07455 b61f4ba21777800908ab8b77443978e2 226 SMART SM00421 157 214 9.8E-27 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS07455 b61f4ba21777800908ab8b77443978e2 226 Gene3D G3DSA:1.10.10.10 129 221 1.3E-33 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS07455 b61f4ba21777800908ab8b77443978e2 226 ProSitePatterns PS00622 LuxR-type HTH domain signature. 174 201 - T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS07455 b61f4ba21777800908ab8b77443978e2 226 SUPERFAMILY SSF52172 3 190 2.49E-32 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS07455 b61f4ba21777800908ab8b77443978e2 226 SMART SM00448 3 120 3.6E-32 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS07455 b61f4ba21777800908ab8b77443978e2 226 Pfam PF00072 Response regulator receiver domain 5 121 5.4E-25 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS07455 b61f4ba21777800908ab8b77443978e2 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 190 202 1.2E-14 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS07455 b61f4ba21777800908ab8b77443978e2 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 174 1.2E-14 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS07455 b61f4ba21777800908ab8b77443978e2 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 174 190 1.2E-14 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS07455 b61f4ba21777800908ab8b77443978e2 226 Gene3D G3DSA:3.40.50.2300 2 128 2.2E-37 T 10-11-2016 A4G23_RS19475 cacf0c80365dbb8b20a563d48a865e52 447 PIRSF PIRSF000098 3 447 3.8E-156 T 10-11-2016 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 A4G23_RS19475 cacf0c80365dbb8b20a563d48a865e52 447 Gene3D G3DSA:3.40.50.720 3 149 1.3E-48 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS19475 cacf0c80365dbb8b20a563d48a865e52 447 SUPERFAMILY SSF55347 138 305 3.47E-54 T 10-11-2016 A4G23_RS19475 cacf0c80365dbb8b20a563d48a865e52 447 Pfam PF01842 ACT domain 353 432 1.1E-10 T 10-11-2016 IPR002912 ACT domain GO:0008152|GO:0016597 A4G23_RS19475 cacf0c80365dbb8b20a563d48a865e52 447 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 184 206 - T 10-11-2016 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 A4G23_RS19475 cacf0c80365dbb8b20a563d48a865e52 447 Gene3D G3DSA:3.30.70.260 350 385 7.5E-8 T 10-11-2016 A4G23_RS19475 cacf0c80365dbb8b20a563d48a865e52 447 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 12 130 1.2E-21 T 10-11-2016 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 A4G23_RS19475 cacf0c80365dbb8b20a563d48a865e52 447 Pfam PF00742 Homoserine dehydrogenase 138 318 1.1E-67 T 10-11-2016 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 A4G23_RS19475 cacf0c80365dbb8b20a563d48a865e52 447 SUPERFAMILY SSF55021 349 439 1.86E-11 T 10-11-2016 A4G23_RS19475 cacf0c80365dbb8b20a563d48a865e52 447 Gene3D G3DSA:3.30.360.10 150 302 8.1E-56 T 10-11-2016 A4G23_RS19475 cacf0c80365dbb8b20a563d48a865e52 447 SUPERFAMILY SSF51735 4 159 4.8E-33 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS17505 403f0ad1211fa372252811c54b50c252 225 Pfam PF08281 Sigma-70, region 4 127 176 1.8E-11 T 10-11-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS17505 403f0ad1211fa372252811c54b50c252 225 SUPERFAMILY SSF88946 4 110 4.19E-25 T 10-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS17505 403f0ad1211fa372252811c54b50c252 225 SUPERFAMILY SSF88659 125 180 6.17E-10 T 10-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS17505 403f0ad1211fa372252811c54b50c252 225 Pfam PF04542 Sigma-70 region 2 27 93 2.5E-16 T 10-11-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS17505 403f0ad1211fa372252811c54b50c252 225 Gene3D G3DSA:1.10.10.10 127 181 1.2E-12 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS17505 403f0ad1211fa372252811c54b50c252 225 Gene3D G3DSA:1.10.1740.10 7 113 1.4E-26 T 10-11-2016 A4G23_RS17505 403f0ad1211fa372252811c54b50c252 225 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 179 7.2E-20 T 10-11-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS19175 44ff1f19f4d21bcc8df5dbd607218bd8 529 SMART SM00220 10 429 4.5E-13 T 10-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4G23_RS19175 44ff1f19f4d21bcc8df5dbd607218bd8 529 Gene3D G3DSA:3.30.200.20 3 91 7.5E-20 T 10-11-2016 A4G23_RS19175 44ff1f19f4d21bcc8df5dbd607218bd8 529 Pfam PF00069 Protein kinase domain 10 174 3.4E-24 T 10-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4G23_RS19175 44ff1f19f4d21bcc8df5dbd607218bd8 529 SUPERFAMILY SSF56112 4 173 8.36E-43 T 10-11-2016 IPR011009 Protein kinase-like domain A4G23_RS19175 44ff1f19f4d21bcc8df5dbd607218bd8 529 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 135 147 - T 10-11-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 A4G23_RS19175 44ff1f19f4d21bcc8df5dbd607218bd8 529 Gene3D G3DSA:1.10.510.10 92 180 2.2E-19 T 10-11-2016 A4G23_RS24220 d7d30110da0068504c009cee0b41785e 491 Gene3D G3DSA:1.10.340.30 319 433 3.7E-34 T 10-11-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A4G23_RS24220 d7d30110da0068504c009cee0b41785e 491 Gene3D G3DSA:1.10.10.60 84 137 6.2E-4 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS24220 d7d30110da0068504c009cee0b41785e 491 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 137 179 - T 10-11-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A4G23_RS24220 d7d30110da0068504c009cee0b41785e 491 SMART SM00478 326 483 5.5E-25 T 10-11-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A4G23_RS24220 d7d30110da0068504c009cee0b41785e 491 SUPERFAMILY SSF57884 2 85 1.07E-30 T 10-11-2016 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 A4G23_RS24220 d7d30110da0068504c009cee0b41785e 491 SUPERFAMILY SSF46689 137 185 5.82E-7 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS24220 d7d30110da0068504c009cee0b41785e 491 Gene3D G3DSA:1.10.10.60 138 185 3.0E-9 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS24220 d7d30110da0068504c009cee0b41785e 491 SUPERFAMILY SSF48150 306 480 3.49E-40 T 10-11-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A4G23_RS24220 d7d30110da0068504c009cee0b41785e 491 SUPERFAMILY SSF55945 202 297 1.57E-24 T 10-11-2016 A4G23_RS24220 d7d30110da0068504c009cee0b41785e 491 SMART SM00342 100 183 4.4E-17 T 10-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4G23_RS24220 d7d30110da0068504c009cee0b41785e 491 Gene3D G3DSA:3.40.10.10 2 83 1.6E-33 T 10-11-2016 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 A4G23_RS24220 d7d30110da0068504c009cee0b41785e 491 SMART SM01009 201 316 1.3E-44 T 10-11-2016 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal A4G23_RS24220 d7d30110da0068504c009cee0b41785e 491 Pfam PF02805 Metal binding domain of Ada 8 71 1.2E-26 T 10-11-2016 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 A4G23_RS24220 d7d30110da0068504c009cee0b41785e 491 Pfam PF06029 AlkA N-terminal domain 202 316 2.7E-29 T 10-11-2016 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal A4G23_RS24220 d7d30110da0068504c009cee0b41785e 491 Pfam PF12833 Helix-turn-helix domain 106 185 1.3E-16 T 10-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4G23_RS24220 d7d30110da0068504c009cee0b41785e 491 Gene3D G3DSA:1.10.1670.10 434 485 1.3E-17 T 10-11-2016 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 A4G23_RS24220 d7d30110da0068504c009cee0b41785e 491 Gene3D G3DSA:3.30.310.20 202 316 3.7E-33 T 10-11-2016 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal A4G23_RS18265 65dfe28d9ecc918ce1e55da4b272fc7b 343 Gene3D G3DSA:3.30.540.10 191 337 1.4E-45 T 10-11-2016 A4G23_RS18265 65dfe28d9ecc918ce1e55da4b272fc7b 343 Gene3D G3DSA:3.30.540.10 17 190 3.4E-64 T 10-11-2016 A4G23_RS18265 65dfe28d9ecc918ce1e55da4b272fc7b 343 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 19 330 1.3E-116 T 10-11-2016 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 A4G23_RS18265 65dfe28d9ecc918ce1e55da4b272fc7b 343 SUPERFAMILY SSF56655 17 329 4.45E-112 T 10-11-2016 A4G23_RS18265 65dfe28d9ecc918ce1e55da4b272fc7b 343 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 19 326 2.4E-142 T 10-11-2016 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 A4G23_RS18265 65dfe28d9ecc918ce1e55da4b272fc7b 343 PIRSF PIRSF004532 17 337 1.5E-145 T 10-11-2016 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 A4G23_RS22125 b4627a1e0cc6b51fbe7b72c0e6c4e229 248 SUPERFAMILY SSF56214 132 236 1.24E-15 T 10-11-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 A4G23_RS22125 b4627a1e0cc6b51fbe7b72c0e6c4e229 248 Gene3D G3DSA:3.90.470.20 137 205 2.4E-13 T 10-11-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 A4G23_RS22125 b4627a1e0cc6b51fbe7b72c0e6c4e229 248 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 132 193 1.4E-11 T 10-11-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 A4G23_RS22125 b4627a1e0cc6b51fbe7b72c0e6c4e229 248 SUPERFAMILY SSF56214 23 123 8.89E-13 T 10-11-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 A4G23_RS22125 b4627a1e0cc6b51fbe7b72c0e6c4e229 248 Gene3D G3DSA:3.90.470.20 34 136 1.9E-21 T 10-11-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 A4G23_RS04740 196439fd62700b90af56191d904ff62f 308 Gene3D G3DSA:3.30.1490.100 165 270 2.7E-17 T 10-11-2016 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A4G23_RS04740 196439fd62700b90af56191d904ff62f 308 Gene3D G3DSA:1.10.150.20 93 160 7.7E-17 T 10-11-2016 A4G23_RS04740 196439fd62700b90af56191d904ff62f 308 SUPERFAMILY SSF100879 163 258 5.69E-17 T 10-11-2016 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A4G23_RS04740 196439fd62700b90af56191d904ff62f 308 Pfam PF11799 impB/mucB/samB family C-terminal domain 163 271 1.8E-12 T 10-11-2016 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A4G23_RS04740 196439fd62700b90af56191d904ff62f 308 Gene3D G3DSA:3.30.70.270 8 86 3.8E-6 T 10-11-2016 A4G23_RS04740 196439fd62700b90af56191d904ff62f 308 SUPERFAMILY SSF56672 5 156 3.11E-28 T 10-11-2016 A4G23_RS04740 196439fd62700b90af56191d904ff62f 308 Pfam PF00817 impB/mucB/samB family 8 77 1.2E-5 T 10-11-2016 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A4G23_RS25960 f84796daefdf1de14367cfa97cb03b94 399 PIRSF PIRSF001134 3 399 1.1E-121 T 10-11-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A4G23_RS25960 f84796daefdf1de14367cfa97cb03b94 399 Gene3D G3DSA:3.30.300.50 56 137 6.2E-26 T 10-11-2016 A4G23_RS25960 f84796daefdf1de14367cfa97cb03b94 399 Pfam PF00089 Trypsin 271 388 4.8E-9 T 10-11-2016 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 A4G23_RS25960 f84796daefdf1de14367cfa97cb03b94 399 Pfam PF02983 Alpha-lytic protease prodomain 139 194 2.6E-9 T 10-11-2016 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 A4G23_RS25960 f84796daefdf1de14367cfa97cb03b94 399 Gene3D G3DSA:2.40.10.10 216 294 3.5E-26 T 10-11-2016 A4G23_RS25960 f84796daefdf1de14367cfa97cb03b94 399 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 298 318 7.1E-40 T 10-11-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A4G23_RS25960 f84796daefdf1de14367cfa97cb03b94 399 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 338 361 7.1E-40 T 10-11-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A4G23_RS25960 f84796daefdf1de14367cfa97cb03b94 399 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 237 251 7.1E-40 T 10-11-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A4G23_RS25960 f84796daefdf1de14367cfa97cb03b94 399 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 362 376 7.1E-40 T 10-11-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A4G23_RS25960 f84796daefdf1de14367cfa97cb03b94 399 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 319 336 7.1E-40 T 10-11-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A4G23_RS25960 f84796daefdf1de14367cfa97cb03b94 399 SUPERFAMILY SSF50494 221 390 3.26E-33 T 10-11-2016 IPR009003 Peptidase S1, PA clan A4G23_RS25960 f84796daefdf1de14367cfa97cb03b94 399 Gene3D G3DSA:3.30.300.50 138 206 2.0E-17 T 10-11-2016 A4G23_RS25960 f84796daefdf1de14367cfa97cb03b94 399 Gene3D G3DSA:2.40.10.10 295 384 3.0E-29 T 10-11-2016 A4G23_RS05980 9a4a51943d45f32da3460d70cf0cd666 271 Gene3D G3DSA:3.40.30.10 81 258 1.5E-32 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS05980 9a4a51943d45f32da3460d70cf0cd666 271 Pfam PF13462 Thioredoxin 84 255 3.0E-25 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS05980 9a4a51943d45f32da3460d70cf0cd666 271 SUPERFAMILY SSF52833 76 244 1.22E-28 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS08210 7f7ec3911df347764913b27bb241db58 1484 Pfam PF10150 Ribonuclease E/G family 771 1040 8.9E-108 T 10-11-2016 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 A4G23_RS08210 7f7ec3911df347764913b27bb241db58 1484 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 667 1066 1.1E-153 T 10-11-2016 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 A4G23_RS08210 7f7ec3911df347764913b27bb241db58 1484 Gene3D G3DSA:2.40.50.140 685 775 1.6E-28 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS08210 7f7ec3911df347764913b27bb241db58 1484 SUPERFAMILY SSF50249 692 775 1.76E-14 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS08210 7f7ec3911df347764913b27bb241db58 1484 SMART SM00316 690 769 3.7E-5 T 10-11-2016 IPR022967 RNA-binding domain, S1 A4G23_RS05755 387ea6b0d0f052be6f07a8532da70fed 183 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 97 175 1.9E-27 T 10-11-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A4G23_RS05755 387ea6b0d0f052be6f07a8532da70fed 183 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 146 152 - T 10-11-2016 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A4G23_RS05755 387ea6b0d0f052be6f07a8532da70fed 183 SUPERFAMILY SSF46767 97 177 8.89E-26 T 10-11-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A4G23_RS05755 387ea6b0d0f052be6f07a8532da70fed 183 SUPERFAMILY SSF53155 19 93 1.43E-8 T 10-11-2016 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A4G23_RS05755 387ea6b0d0f052be6f07a8532da70fed 183 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 11 178 37.106 T 10-11-2016 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 A4G23_RS05755 387ea6b0d0f052be6f07a8532da70fed 183 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 97 177 8.5E-29 T 10-11-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A4G23_RS05755 387ea6b0d0f052be6f07a8532da70fed 183 Gene3D G3DSA:1.10.10.10 96 177 2.4E-29 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS05755 387ea6b0d0f052be6f07a8532da70fed 183 Gene3D G3DSA:3.30.160.70 4 90 2.0E-5 T 10-11-2016 A4G23_RS22795 7aac56c2fb9f049e57d8eaca8a2582f2 367 PIRSF PIRSF005508 6 365 1.8E-140 T 10-11-2016 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 A4G23_RS22795 7aac56c2fb9f049e57d8eaca8a2582f2 367 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 19 348 1.2E-132 T 10-11-2016 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 A4G23_RS22795 7aac56c2fb9f049e57d8eaca8a2582f2 367 Pfam PF01758 Sodium Bile acid symporter family 64 261 7.6E-61 T 10-11-2016 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 A4G23_RS11725 73c82035c3845c5fedba5978a84ca66b 214 SUPERFAMILY SSF50475 18 200 2.83E-36 T 10-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 A4G23_RS11725 73c82035c3845c5fedba5978a84ca66b 214 SMART SM00903 20 179 0.0046 T 10-11-2016 IPR002563 Flavin reductase like domain GO:0010181 A4G23_RS11725 73c82035c3845c5fedba5978a84ca66b 214 Pfam PF01613 Flavin reductase like domain 23 196 5.1E-18 T 10-11-2016 IPR002563 Flavin reductase like domain GO:0010181 A4G23_RS11725 73c82035c3845c5fedba5978a84ca66b 214 Gene3D G3DSA:2.30.110.10 16 201 6.2E-40 T 10-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 A4G23_RS21770 8ce37fc80341b1402c3f3627fd256178 458 Pfam PF00144 Beta-lactamase 9 332 8.9E-58 T 10-11-2016 IPR001466 Beta-lactamase-related A4G23_RS21770 8ce37fc80341b1402c3f3627fd256178 458 SUPERFAMILY SSF56601 6 336 4.51E-65 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS21770 8ce37fc80341b1402c3f3627fd256178 458 Gene3D G3DSA:3.40.710.10 14 334 2.2E-64 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS21925 fc4b76f701e69cd26616fc9d7bd45114 180 SUPERFAMILY SSF51161 49 180 3.88E-36 T 10-11-2016 IPR011004 Trimeric LpxA-like A4G23_RS21925 fc4b76f701e69cd26616fc9d7bd45114 180 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 131 160 4.7E-9 T 10-11-2016 IPR001451 Hexapeptide repeat A4G23_RS21925 fc4b76f701e69cd26616fc9d7bd45114 180 Gene3D G3DSA:2.160.10.10 7 179 4.3E-41 T 10-11-2016 A4G23_RS21925 fc4b76f701e69cd26616fc9d7bd45114 180 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 135 163 - T 10-11-2016 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 A4G23_RS05900 16674a2160e532c15c4803d72b516336 217 PIRSF PIRSF036382 15 212 9.6E-71 T 10-11-2016 IPR008327 Signal transduction response regulator, antiterminator A4G23_RS05900 16674a2160e532c15c4803d72b516336 217 Gene3D G3DSA:1.10.10.10 152 209 7.3E-25 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS05900 16674a2160e532c15c4803d72b516336 217 Pfam PF00072 Response regulator receiver domain 25 134 2.6E-28 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS05900 16674a2160e532c15c4803d72b516336 217 SMART SM01012 150 205 4.9E-24 T 10-11-2016 IPR005561 ANTAR domain GO:0003723 A4G23_RS05900 16674a2160e532c15c4803d72b516336 217 Pfam PF03861 ANTAR domain 153 205 7.5E-21 T 10-11-2016 IPR005561 ANTAR domain GO:0003723 A4G23_RS05900 16674a2160e532c15c4803d72b516336 217 SUPERFAMILY SSF52172 22 205 3.13E-56 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS05900 16674a2160e532c15c4803d72b516336 217 SMART SM00448 23 134 7.2E-38 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS05900 16674a2160e532c15c4803d72b516336 217 Gene3D G3DSA:3.40.50.2300 22 144 1.2E-37 T 10-11-2016 A4G23_RS20885 baf0941c8c1980b9d6aee5c92c17dc06 166 SUPERFAMILY SSF75420 3 85 4.45E-20 T 10-11-2016 IPR028989 Ribosome maturation factor RimP, N-terminal A4G23_RS20885 baf0941c8c1980b9d6aee5c92c17dc06 166 Gene3D G3DSA:3.30.300.70 3 82 5.3E-25 T 10-11-2016 IPR028989 Ribosome maturation factor RimP, N-terminal A4G23_RS20885 baf0941c8c1980b9d6aee5c92c17dc06 166 Pfam PF02576 Putative ribosome maturation factor RimP 12 151 4.7E-37 T 10-11-2016 IPR003728 Ribosome maturation factor RimP GO:0042274 A4G23_RS20885 baf0941c8c1980b9d6aee5c92c17dc06 166 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 7 155 21.975 T 10-11-2016 IPR003728 Ribosome maturation factor RimP GO:0042274 A4G23_RS04060 50c5a60c496348ff74fe0b7fdd4691d6 389 SUPERFAMILY SSF53335 210 363 4.65E-27 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS04060 50c5a60c496348ff74fe0b7fdd4691d6 389 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 317 323 - T 10-11-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A4G23_RS04060 50c5a60c496348ff74fe0b7fdd4691d6 389 Pfam PF05175 Methyltransferase small domain 215 385 3.9E-52 T 10-11-2016 IPR007848 Methyltransferase small domain GO:0008168 A4G23_RS04060 50c5a60c496348ff74fe0b7fdd4691d6 389 PIRSF PIRSF037565 1 389 1.1E-130 T 10-11-2016 IPR017237 rRNA (guanine-N2-)-methyltransferase, RsmD GO:0005737|GO:0008990|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A4G23_RS04060 50c5a60c496348ff74fe0b7fdd4691d6 389 Gene3D G3DSA:3.40.50.150 211 388 1.1E-23 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS04060 50c5a60c496348ff74fe0b7fdd4691d6 389 Hamap MF_01859 Ribosomal RNA large subunit methyltransferase G [rlmG]. 1 388 44.573 T 10-11-2016 IPR017237 rRNA (guanine-N2-)-methyltransferase, RsmD GO:0005737|GO:0008990|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A4G23_RS10720 ed68eac808d9233111c51d0d29898546 1226 Pfam PF03572 Peptidase family S41 1020 1174 1.4E-23 T 10-11-2016 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 A4G23_RS10720 ed68eac808d9233111c51d0d29898546 1226 Gene3D G3DSA:3.90.226.10 999 1205 1.3E-38 T 10-11-2016 IPR029045 ClpP/crotonase-like domain A4G23_RS10720 ed68eac808d9233111c51d0d29898546 1226 SUPERFAMILY SSF50156 902 981 1.03E-14 T 10-11-2016 IPR001478 PDZ domain GO:0005515 A4G23_RS10720 ed68eac808d9233111c51d0d29898546 1226 Gene3D G3DSA:2.130.10.10 335 412 1.6E-87 T 10-11-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 A4G23_RS10720 ed68eac808d9233111c51d0d29898546 1226 Gene3D G3DSA:2.130.10.10 253 278 1.6E-87 T 10-11-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 A4G23_RS10720 ed68eac808d9233111c51d0d29898546 1226 Gene3D G3DSA:2.130.10.10 559 808 1.6E-87 T 10-11-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 A4G23_RS10720 ed68eac808d9233111c51d0d29898546 1226 Pfam PF14685 Tricorn protease PDZ domain 902 990 3.6E-24 T 10-11-2016 IPR029414 Tricorn protease, PDZ domain A4G23_RS10720 ed68eac808d9233111c51d0d29898546 1226 Pfam PF14684 Tricorn protease C1 domain 820 887 1.2E-26 T 10-11-2016 IPR028204 Tricorn protease C1 domain A4G23_RS10720 ed68eac808d9233111c51d0d29898546 1226 Pfam PF07676 WD40-like Beta Propeller Repeat 572 585 0.26 T 10-11-2016 IPR011659 WD40-like Beta Propeller A4G23_RS10720 ed68eac808d9233111c51d0d29898546 1226 Pfam PF07676 WD40-like Beta Propeller Repeat 53 75 0.0025 T 10-11-2016 IPR011659 WD40-like Beta Propeller A4G23_RS10720 ed68eac808d9233111c51d0d29898546 1226 Pfam PF07676 WD40-like Beta Propeller Repeat 608 640 7.5E-4 T 10-11-2016 IPR011659 WD40-like Beta Propeller A4G23_RS10720 ed68eac808d9233111c51d0d29898546 1226 SUPERFAMILY SSF69304 10 263 9.55E-32 T 10-11-2016 A4G23_RS10720 ed68eac808d9233111c51d0d29898546 1226 Gene3D G3DSA:2.30.42.10 901 996 7.2E-30 T 10-11-2016 IPR001478 PDZ domain GO:0005515 A4G23_RS10720 ed68eac808d9233111c51d0d29898546 1226 Gene3D G3DSA:3.30.750.44 817 887 3.9E-30 T 10-11-2016 A4G23_RS10720 ed68eac808d9233111c51d0d29898546 1226 Gene3D G3DSA:2.120.10.60 5 252 1.6E-60 T 10-11-2016 A4G23_RS10720 ed68eac808d9233111c51d0d29898546 1226 SMART SM00245 983 1175 5.8E-17 T 10-11-2016 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 A4G23_RS10720 ed68eac808d9233111c51d0d29898546 1226 SUPERFAMILY SSF50969 562 674 2.35E-19 T 10-11-2016 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like A4G23_RS10720 ed68eac808d9233111c51d0d29898546 1226 SUPERFAMILY SSF50969 231 422 2.35E-19 T 10-11-2016 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like A4G23_RS10720 ed68eac808d9233111c51d0d29898546 1226 SUPERFAMILY SSF52096 992 1200 2.15E-62 T 10-11-2016 IPR029045 ClpP/crotonase-like domain A4G23_RS10720 ed68eac808d9233111c51d0d29898546 1226 SUPERFAMILY SSF52096 817 896 2.15E-62 T 10-11-2016 IPR029045 ClpP/crotonase-like domain A4G23_RS19140 60620ed692f59705894138a4fcedd1bb 255 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS19140 60620ed692f59705894138a4fcedd1bb 255 PIRSF PIRSF039085 3 255 7.6E-125 T 10-11-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 A4G23_RS19140 60620ed692f59705894138a4fcedd1bb 255 SMART SM00382 31 228 7.0E-17 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS19140 60620ed692f59705894138a4fcedd1bb 255 Gene3D G3DSA:3.40.50.300 5 252 1.3E-82 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS19140 60620ed692f59705894138a4fcedd1bb 255 Pfam PF00005 ABC transporter 22 180 2.8E-32 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS19140 60620ed692f59705894138a4fcedd1bb 255 SUPERFAMILY SSF52540 6 250 1.98E-80 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS04910 94dbd91af88239f7c990d47645e208e9 784 Pfam PF00931 NB-ARC domain 143 330 2.2E-10 T 10-11-2016 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6803207 A4G23_RS04910 94dbd91af88239f7c990d47645e208e9 784 SUPERFAMILY SSF52540 117 368 3.36E-21 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS04910 94dbd91af88239f7c990d47645e208e9 784 Gene3D G3DSA:3.40.50.300 161 242 1.2E-6 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS04910 94dbd91af88239f7c990d47645e208e9 784 Gene3D G3DSA:3.40.50.300 112 160 3.0E-4 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS04910 94dbd91af88239f7c990d47645e208e9 784 SMART SM00028 607 640 230.0 T 10-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 A4G23_RS04910 94dbd91af88239f7c990d47645e208e9 784 SMART SM00028 647 680 4.1 T 10-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 A4G23_RS04910 94dbd91af88239f7c990d47645e208e9 784 SMART SM00028 567 600 310.0 T 10-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 A4G23_RS04910 94dbd91af88239f7c990d47645e208e9 784 SMART SM00028 687 720 130.0 T 10-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 A4G23_RS04910 94dbd91af88239f7c990d47645e208e9 784 PRINTS PR00364 Disease resistance protein signature 150 165 1.3E-5 T 10-11-2016 A4G23_RS04910 94dbd91af88239f7c990d47645e208e9 784 PRINTS PR00364 Disease resistance protein signature 226 240 1.3E-5 T 10-11-2016 A4G23_RS04910 94dbd91af88239f7c990d47645e208e9 784 PRINTS PR00364 Disease resistance protein signature 311 325 1.3E-5 T 10-11-2016 A4G23_RS04910 94dbd91af88239f7c990d47645e208e9 784 Pfam PF13424 Tetratricopeptide repeat 646 707 1.8E-7 T 10-11-2016 A4G23_RS04910 94dbd91af88239f7c990d47645e208e9 784 Pfam PF13424 Tetratricopeptide repeat 566 637 1.7E-8 T 10-11-2016 A4G23_RS04910 94dbd91af88239f7c990d47645e208e9 784 Gene3D G3DSA:1.10.10.10 384 424 8.7E-4 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS04910 94dbd91af88239f7c990d47645e208e9 784 SUPERFAMILY SSF48452 554 733 2.28E-18 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS04910 94dbd91af88239f7c990d47645e208e9 784 SMART SM00382 147 289 0.0037 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS04910 94dbd91af88239f7c990d47645e208e9 784 Gene3D G3DSA:1.25.40.10 565 746 3.1E-19 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS22465 94988b240c14140feebed65b2b6ab20f 472 Gene3D G3DSA:3.50.50.60 1 38 4.8E-18 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS22465 94988b240c14140feebed65b2b6ab20f 472 Gene3D G3DSA:3.50.50.60 250 324 4.8E-18 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS22465 94988b240c14140feebed65b2b6ab20f 472 Gene3D G3DSA:3.50.50.60 412 447 4.8E-18 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS22465 94988b240c14140feebed65b2b6ab20f 472 Pfam PF01593 Flavin containing amine oxidoreductase 238 347 2.6E-9 T 10-11-2016 IPR002937 Amine oxidase GO:0016491|GO:0055114 A4G23_RS22465 94988b240c14140feebed65b2b6ab20f 472 SUPERFAMILY SSF51905 149 345 1.94E-20 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS22465 94988b240c14140feebed65b2b6ab20f 472 SUPERFAMILY SSF51905 419 447 1.94E-20 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS22465 94988b240c14140feebed65b2b6ab20f 472 SUPERFAMILY SSF51905 2 109 1.94E-20 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS21385 a6dce284be886c4d322933ba1b4b2113 520 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 283 508 2.0E-36 T 10-11-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS21385 a6dce284be886c4d322933ba1b4b2113 520 Gene3D G3DSA:1.10.601.10 100 356 3.9E-71 T 10-11-2016 A4G23_RS21385 a6dce284be886c4d322933ba1b4b2113 520 Pfam PF04539 Sigma-70 region 3 366 442 1.1E-28 T 10-11-2016 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS21385 a6dce284be886c4d322933ba1b4b2113 520 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 283 519 9.3E-113 T 10-11-2016 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 A4G23_RS21385 a6dce284be886c4d322933ba1b4b2113 520 Pfam PF04542 Sigma-70 region 2 287 356 3.1E-22 T 10-11-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS21385 a6dce284be886c4d322933ba1b4b2113 520 Pfam PF04545 Sigma-70, region 4 455 508 3.0E-18 T 10-11-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS21385 a6dce284be886c4d322933ba1b4b2113 520 Pfam PF00140 Sigma-70 factor, region 1.2 222 255 8.2E-17 T 10-11-2016 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS21385 a6dce284be886c4d322933ba1b4b2113 520 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 311 324 - T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS21385 a6dce284be886c4d322933ba1b4b2113 520 Gene3D G3DSA:1.10.10.10 449 520 2.0E-31 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS21385 a6dce284be886c4d322933ba1b4b2113 520 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 115 520 31.837 T 10-11-2016 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 A4G23_RS21385 a6dce284be886c4d322933ba1b4b2113 520 SUPERFAMILY SSF88659 418 519 2.62E-27 T 10-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS21385 a6dce284be886c4d322933ba1b4b2113 520 SUPERFAMILY SSF88659 360 433 3.92E-21 T 10-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS21385 a6dce284be886c4d322933ba1b4b2113 520 PRINTS PR00046 Major sigma-70 factor signature 459 471 7.3E-29 T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS21385 a6dce284be886c4d322933ba1b4b2113 520 PRINTS PR00046 Major sigma-70 factor signature 311 324 7.3E-29 T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS21385 a6dce284be886c4d322933ba1b4b2113 520 PRINTS PR00046 Major sigma-70 factor signature 480 495 7.3E-29 T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS21385 a6dce284be886c4d322933ba1b4b2113 520 PRINTS PR00046 Major sigma-70 factor signature 495 506 7.3E-29 T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS21385 a6dce284be886c4d322933ba1b4b2113 520 PRINTS PR00046 Major sigma-70 factor signature 335 343 7.3E-29 T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS21385 a6dce284be886c4d322933ba1b4b2113 520 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 480 506 - T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS21385 a6dce284be886c4d322933ba1b4b2113 520 SUPERFAMILY SSF88946 219 357 6.28E-54 T 10-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS21385 a6dce284be886c4d322933ba1b4b2113 520 Gene3D G3DSA:1.10.10.10 360 411 3.9E-26 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS13115 95cc2462d0c4fca06898e31e6a7e9187 609 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 3 34 8.9E-11 T 10-11-2016 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria A4G23_RS13115 95cc2462d0c4fca06898e31e6a7e9187 609 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 162 272 1.6E-18 T 10-11-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 A4G23_RS13115 95cc2462d0c4fca06898e31e6a7e9187 609 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 472 605 6.9E-31 T 10-11-2016 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain A4G23_RS13115 95cc2462d0c4fca06898e31e6a7e9187 609 Gene3D G3DSA:2.40.110.10 161 272 1.3E-25 T 10-11-2016 A4G23_RS13115 95cc2462d0c4fca06898e31e6a7e9187 609 Gene3D G3DSA:1.10.540.10 36 148 9.1E-4 T 10-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 A4G23_RS13115 95cc2462d0c4fca06898e31e6a7e9187 609 SUPERFAMILY SSF56645 37 282 1.09E-40 T 10-11-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 A4G23_RS13115 95cc2462d0c4fca06898e31e6a7e9187 609 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 286 452 4.6E-16 T 10-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4G23_RS13115 95cc2462d0c4fca06898e31e6a7e9187 609 SUPERFAMILY SSF47203 290 470 8.54E-32 T 10-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4G23_RS13115 95cc2462d0c4fca06898e31e6a7e9187 609 Gene3D G3DSA:1.20.140.10 273 466 1.7E-41 T 10-11-2016 A4G23_RS04505 8dca749eb97d4b2b2a92bb3d2241f17f 467 PIRSF PIRSF002746 22 467 1.5E-141 T 10-11-2016 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 A4G23_RS04505 8dca749eb97d4b2b2a92bb3d2241f17f 467 Pfam PF02447 GntP family permease 29 466 1.2E-139 T 10-11-2016 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 A4G23_RS04505 8dca749eb97d4b2b2a92bb3d2241f17f 467 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 30 467 5.8E-134 T 10-11-2016 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 A4G23_RS20735 00350c55aa315728ce59d5d2e196116e 434 SUPERFAMILY SSF103473 18 424 1.44E-38 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS20735 00350c55aa315728ce59d5d2e196116e 434 Gene3D G3DSA:1.20.1250.20 18 202 2.1E-12 T 10-11-2016 A4G23_RS20735 00350c55aa315728ce59d5d2e196116e 434 Gene3D G3DSA:1.20.1250.20 245 423 1.6E-14 T 10-11-2016 A4G23_RS20735 00350c55aa315728ce59d5d2e196116e 434 Pfam PF05977 Transmembrane secretion effector 20 198 4.8E-18 T 10-11-2016 IPR010290 Transmembrane secretion effector A4G23_RS20735 00350c55aa315728ce59d5d2e196116e 434 Pfam PF05977 Transmembrane secretion effector 230 431 9.5E-8 T 10-11-2016 IPR010290 Transmembrane secretion effector A4G23_RS11625 4c2cc31eb10990cf9ffea5684f0cc600 370 SUPERFAMILY SSF53633 6 243 1.83E-45 T 10-11-2016 IPR001048 Aspartate/glutamate/uridylate kinase A4G23_RS11625 4c2cc31eb10990cf9ffea5684f0cc600 370 Pfam PF00696 Amino acid kinase family 6 229 4.4E-32 T 10-11-2016 IPR001048 Aspartate/glutamate/uridylate kinase A4G23_RS11625 4c2cc31eb10990cf9ffea5684f0cc600 370 Gene3D G3DSA:3.40.1160.10 6 241 7.8E-41 T 10-11-2016 IPR001048 Aspartate/glutamate/uridylate kinase A4G23_RS16995 e7adc3df6bbbd0ac8e434f66020abe23 646 SUPERFAMILY SSF56112 9 276 4.05E-66 T 10-11-2016 IPR011009 Protein kinase-like domain A4G23_RS16995 e7adc3df6bbbd0ac8e434f66020abe23 646 Pfam PF00069 Protein kinase domain 22 266 2.1E-46 T 10-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4G23_RS16995 e7adc3df6bbbd0ac8e434f66020abe23 646 SMART SM00220 21 279 1.0E-55 T 10-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4G23_RS16995 e7adc3df6bbbd0ac8e434f66020abe23 646 Gene3D G3DSA:3.30.200.20 11 90 3.5E-23 T 10-11-2016 A4G23_RS16995 e7adc3df6bbbd0ac8e434f66020abe23 646 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 144 156 - T 10-11-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 A4G23_RS16995 e7adc3df6bbbd0ac8e434f66020abe23 646 Gene3D G3DSA:1.10.510.10 91 274 1.6E-45 T 10-11-2016 A4G23_RS16995 e7adc3df6bbbd0ac8e434f66020abe23 646 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 27 50 - T 10-11-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 A4G23_RS01920 23abd4aede29c264bed128cb95f478e8 865 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 819 835 1.9E-6 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS01920 23abd4aede29c264bed128cb95f478e8 865 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 805 819 1.9E-6 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS01920 23abd4aede29c264bed128cb95f478e8 865 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 835 847 1.9E-6 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS01920 23abd4aede29c264bed128cb95f478e8 865 SMART SM00421 802 859 1.0E-20 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS01920 23abd4aede29c264bed128cb95f478e8 865 SUPERFAMILY SSF52540 114 222 1.31E-11 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS01920 23abd4aede29c264bed128cb95f478e8 865 SUPERFAMILY SSF52540 32 85 1.31E-11 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS01920 23abd4aede29c264bed128cb95f478e8 865 Pfam PF00196 Bacterial regulatory proteins, luxR family 805 859 4.6E-14 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS01920 23abd4aede29c264bed128cb95f478e8 865 Pfam PF13401 AAA domain 32 158 6.5E-7 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS01920 23abd4aede29c264bed128cb95f478e8 865 Gene3D G3DSA:3.40.50.300 31 159 1.8E-8 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS01920 23abd4aede29c264bed128cb95f478e8 865 SUPERFAMILY SSF46894 793 865 7.82E-18 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS01920 23abd4aede29c264bed128cb95f478e8 865 SMART SM00382 29 218 2.4E-6 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS01920 23abd4aede29c264bed128cb95f478e8 865 Gene3D G3DSA:1.10.10.10 801 865 1.9E-20 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS03015 aafd9f8d4ac18e358e2863eda202b26f 269 Gene3D G3DSA:3.10.310.10 1 125 1.2E-42 T 10-11-2016 A4G23_RS03015 aafd9f8d4ac18e358e2863eda202b26f 269 SUPERFAMILY SSF54506 2 267 1.7E-72 T 10-11-2016 A4G23_RS03015 aafd9f8d4ac18e358e2863eda202b26f 269 PIRSF PIRSF016184 1 269 1.1E-51 T 10-11-2016 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 A4G23_RS03015 aafd9f8d4ac18e358e2863eda202b26f 269 Pfam PF02567 Phenazine biosynthesis-like protein 6 265 1.8E-61 T 10-11-2016 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 A4G23_RS03015 aafd9f8d4ac18e358e2863eda202b26f 269 Gene3D G3DSA:3.10.310.10 126 257 5.4E-39 T 10-11-2016 A4G23_RS03015 aafd9f8d4ac18e358e2863eda202b26f 269 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 4 266 1.1E-38 T 10-11-2016 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 A4G23_RS17480 53f580ef4aa243416bff0baeb884bcc5 333 SUPERFAMILY SSF46894 254 322 1.12E-9 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS17480 53f580ef4aa243416bff0baeb884bcc5 333 SMART SM00421 258 315 1.7E-5 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS17480 53f580ef4aa243416bff0baeb884bcc5 333 Pfam PF00196 Bacterial regulatory proteins, luxR family 265 311 2.7E-6 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS17480 53f580ef4aa243416bff0baeb884bcc5 333 Gene3D G3DSA:1.10.10.10 258 321 1.2E-10 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS07930 90be3d6b2a8739135cfe596eebe70bd4 338 Pfam PF01628 HrcA protein C terminal domain 103 321 1.5E-61 T 10-11-2016 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 A4G23_RS07930 90be3d6b2a8739135cfe596eebe70bd4 338 Gene3D G3DSA:1.10.10.10 2 84 1.0E-35 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS07930 90be3d6b2a8739135cfe596eebe70bd4 338 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 3 334 7.1E-100 T 10-11-2016 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 A4G23_RS07930 90be3d6b2a8739135cfe596eebe70bd4 338 Gene3D G3DSA:3.30.450.40 176 337 1.2E-43 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS07930 90be3d6b2a8739135cfe596eebe70bd4 338 SUPERFAMILY SSF55781 71 336 1.96E-57 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS07930 90be3d6b2a8739135cfe596eebe70bd4 338 PIRSF PIRSF005485 1 338 6.6E-100 T 10-11-2016 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 A4G23_RS07930 90be3d6b2a8739135cfe596eebe70bd4 338 SUPERFAMILY SSF46785 2 83 9.99E-24 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS07930 90be3d6b2a8739135cfe596eebe70bd4 338 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 1 328 28.212 T 10-11-2016 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 A4G23_RS16005 43845b05fa7be963b48b849f0204dbb6 203 Gene3D G3DSA:2.30.40.10 15 58 2.4E-7 T 10-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4G23_RS16005 43845b05fa7be963b48b849f0204dbb6 203 SUPERFAMILY SSF51338 7 56 1.68E-13 T 10-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4G23_RS15255 65ceaf42e74b981842d72828fed4a3c5 375 TIGRFAM TIGR03883 DUF2342_F420: uncharacterized protein, coenzyme F420 biosynthesis associated 10 371 3.9E-142 T 10-11-2016 IPR022454 Conserved hypothetical protein CHP03883, F420 biosynthesis associated A4G23_RS15255 65ceaf42e74b981842d72828fed4a3c5 375 SUPERFAMILY SSF55486 9 370 2.56E-106 T 10-11-2016 A4G23_RS15255 65ceaf42e74b981842d72828fed4a3c5 375 TIGRFAM TIGR03624 TIGR03624: putative hydrolase 10 371 5.2E-125 T 10-11-2016 IPR018766 Zinicin-like metallopeptidase type 2 A4G23_RS15255 65ceaf42e74b981842d72828fed4a3c5 375 Pfam PF10103 Zinicin-like metallopeptidase 10 367 7.2E-121 T 10-11-2016 IPR018766 Zinicin-like metallopeptidase type 2 A4G23_RS26970 16691e3ba119f82a04417baa606bcd1a 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 10-11-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4G23_RS26970 16691e3ba119f82a04417baa606bcd1a 254 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 189 1.3E-4 T 10-11-2016 A4G23_RS26970 16691e3ba119f82a04417baa606bcd1a 254 SUPERFAMILY SSF51735 5 226 1.65E-57 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS26970 16691e3ba119f82a04417baa606bcd1a 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 9.2E-9 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS26970 16691e3ba119f82a04417baa606bcd1a 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 9.2E-9 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS26970 16691e3ba119f82a04417baa606bcd1a 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 9.2E-9 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS26970 16691e3ba119f82a04417baa606bcd1a 254 Pfam PF00106 short chain dehydrogenase 8 192 5.7E-46 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS26970 16691e3ba119f82a04417baa606bcd1a 254 Gene3D G3DSA:3.40.50.720 7 200 4.2E-58 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS26970 16691e3ba119f82a04417baa606bcd1a 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 7.1E-28 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS26970 16691e3ba119f82a04417baa606bcd1a 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 7.1E-28 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS26970 16691e3ba119f82a04417baa606bcd1a 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 7.1E-28 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS26970 16691e3ba119f82a04417baa606bcd1a 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 7.1E-28 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS26970 16691e3ba119f82a04417baa606bcd1a 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 7.1E-28 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS09755 c61665bdd08fb0eab931650e11b55ed1 581 SUPERFAMILY SSF56112 6 276 5.93E-81 T 10-11-2016 IPR011009 Protein kinase-like domain A4G23_RS09755 c61665bdd08fb0eab931650e11b55ed1 581 SUPERFAMILY SSF56112 419 485 5.93E-81 T 10-11-2016 IPR011009 Protein kinase-like domain A4G23_RS09755 c61665bdd08fb0eab931650e11b55ed1 581 Gene3D G3DSA:1.10.510.10 117 274 8.0E-55 T 10-11-2016 A4G23_RS09755 c61665bdd08fb0eab931650e11b55ed1 581 Gene3D G3DSA:1.10.510.10 428 455 8.0E-55 T 10-11-2016 A4G23_RS09755 c61665bdd08fb0eab931650e11b55ed1 581 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 138 150 - T 10-11-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 A4G23_RS09755 c61665bdd08fb0eab931650e11b55ed1 581 Pfam PF00069 Protein kinase domain 10 269 4.5E-52 T 10-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4G23_RS09755 c61665bdd08fb0eab931650e11b55ed1 581 Gene3D G3DSA:3.30.200.20 5 116 6.6E-23 T 10-11-2016 A4G23_RS09755 c61665bdd08fb0eab931650e11b55ed1 581 SMART SM00220 8 276 4.9E-75 T 10-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4G23_RS20695 44fc0e1a1c36de398c162a99db51ba29 415 SUPERFAMILY SSF53850 74 411 2.17E-54 T 10-11-2016 A4G23_RS20695 44fc0e1a1c36de398c162a99db51ba29 415 Gene3D G3DSA:3.40.190.10 89 198 2.2E-6 T 10-11-2016 A4G23_RS20695 44fc0e1a1c36de398c162a99db51ba29 415 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 136 150 2.3E-9 T 10-11-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 A4G23_RS20695 44fc0e1a1c36de398c162a99db51ba29 415 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 312 331 2.3E-9 T 10-11-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 A4G23_RS20695 44fc0e1a1c36de398c162a99db51ba29 415 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 152 165 2.3E-9 T 10-11-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 A4G23_RS20695 44fc0e1a1c36de398c162a99db51ba29 415 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 268 287 2.3E-9 T 10-11-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 A4G23_RS20695 44fc0e1a1c36de398c162a99db51ba29 415 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 229 248 2.3E-9 T 10-11-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 A4G23_RS20695 44fc0e1a1c36de398c162a99db51ba29 415 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 184 200 2.3E-9 T 10-11-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 A4G23_RS20695 44fc0e1a1c36de398c162a99db51ba29 415 Gene3D G3DSA:3.40.190.10 199 361 1.0E-38 T 10-11-2016 A4G23_RS20695 44fc0e1a1c36de398c162a99db51ba29 415 Pfam PF13416 Bacterial extracellular solute-binding protein 99 365 2.0E-22 T 10-11-2016 A4G23_RS20520 323b5db659ae64427f05d3f3bb198324 116 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 3 113 1.3E-47 T 10-11-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS20520 323b5db659ae64427f05d3f3bb198324 116 Pfam PF01245 Ribosomal protein L19 4 113 2.8E-49 T 10-11-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS20520 323b5db659ae64427f05d3f3bb198324 116 PIRSF PIRSF002191 1 116 3.6E-48 T 10-11-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS20520 323b5db659ae64427f05d3f3bb198324 116 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 2 114 28.832 T 10-11-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS20520 323b5db659ae64427f05d3f3bb198324 116 PRINTS PR00061 Ribosomal protein L19 signature 88 113 9.8E-42 T 10-11-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS20520 323b5db659ae64427f05d3f3bb198324 116 PRINTS PR00061 Ribosomal protein L19 signature 34 63 9.8E-42 T 10-11-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS20520 323b5db659ae64427f05d3f3bb198324 116 PRINTS PR00061 Ribosomal protein L19 signature 4 33 9.8E-42 T 10-11-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS20520 323b5db659ae64427f05d3f3bb198324 116 SUPERFAMILY SSF50104 3 115 8.02E-45 T 10-11-2016 IPR008991 Translation protein SH3-like domain A4G23_RS20520 323b5db659ae64427f05d3f3bb198324 116 ProSitePatterns PS01015 Ribosomal protein L19 signature. 86 101 - T 10-11-2016 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS22550 0d3dc927e7b7688908c6f25a96b630ec 385 PRINTS PR00313 NodO calcium binding signature 111 119 1.1E-8 T 10-11-2016 A4G23_RS22550 0d3dc927e7b7688908c6f25a96b630ec 385 PRINTS PR00313 NodO calcium binding signature 93 101 1.1E-8 T 10-11-2016 A4G23_RS22550 0d3dc927e7b7688908c6f25a96b630ec 385 PRINTS PR00313 NodO calcium binding signature 140 149 1.1E-8 T 10-11-2016 A4G23_RS22550 0d3dc927e7b7688908c6f25a96b630ec 385 PRINTS PR00313 NodO calcium binding signature 72 83 1.1E-8 T 10-11-2016 A4G23_RS22550 0d3dc927e7b7688908c6f25a96b630ec 385 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 98 116 - T 10-11-2016 IPR018511 Hemolysin-type calcium-binding conserved site A4G23_RS22550 0d3dc927e7b7688908c6f25a96b630ec 385 SUPERFAMILY SSF51120 38 124 5.36E-18 T 10-11-2016 IPR011049 Serralysin-like metalloprotease, C-terminal A4G23_RS22550 0d3dc927e7b7688908c6f25a96b630ec 385 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 111 123 1.5 T 10-11-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 A4G23_RS22550 0d3dc927e7b7688908c6f25a96b630ec 385 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 133 147 0.6 T 10-11-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 A4G23_RS22550 0d3dc927e7b7688908c6f25a96b630ec 385 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 65 82 0.021 T 10-11-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 A4G23_RS22550 0d3dc927e7b7688908c6f25a96b630ec 385 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 185 201 1.4 T 10-11-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 A4G23_RS22550 0d3dc927e7b7688908c6f25a96b630ec 385 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 213 224 32.0 T 10-11-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 A4G23_RS22550 0d3dc927e7b7688908c6f25a96b630ec 385 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 309 318 11.0 T 10-11-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 A4G23_RS22550 0d3dc927e7b7688908c6f25a96b630ec 385 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 337 353 0.47 T 10-11-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 A4G23_RS22550 0d3dc927e7b7688908c6f25a96b630ec 385 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 163 175 8.2 T 10-11-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 A4G23_RS22550 0d3dc927e7b7688908c6f25a96b630ec 385 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 92 109 0.0027 T 10-11-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 A4G23_RS22550 0d3dc927e7b7688908c6f25a96b630ec 385 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 271 282 23.0 T 10-11-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 A4G23_RS22550 0d3dc927e7b7688908c6f25a96b630ec 385 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 62 80 - T 10-11-2016 IPR018511 Hemolysin-type calcium-binding conserved site A4G23_RS22550 0d3dc927e7b7688908c6f25a96b630ec 385 Gene3D G3DSA:2.150.10.10 56 218 8.8E-22 T 10-11-2016 IPR011049 Serralysin-like metalloprotease, C-terminal A4G23_RS22550 0d3dc927e7b7688908c6f25a96b630ec 385 Gene3D G3DSA:2.150.10.10 241 379 1.5E-4 T 10-11-2016 IPR011049 Serralysin-like metalloprotease, C-terminal A4G23_RS22550 0d3dc927e7b7688908c6f25a96b630ec 385 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 342 360 - T 10-11-2016 IPR018511 Hemolysin-type calcium-binding conserved site A4G23_RS11500 06532dcd04cdfc70c6652fbc34d09964 437 Gene3D G3DSA:3.30.450.20 14 123 1.2E-16 T 10-11-2016 A4G23_RS11500 06532dcd04cdfc70c6652fbc34d09964 437 SMART SM00091 14 82 1.9E-6 T 10-11-2016 IPR000014 PAS domain A4G23_RS11500 06532dcd04cdfc70c6652fbc34d09964 437 SMART SM00091 138 203 6.1E-5 T 10-11-2016 IPR000014 PAS domain A4G23_RS11500 06532dcd04cdfc70c6652fbc34d09964 437 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 15 130 8.1E-9 T 10-11-2016 IPR000014 PAS domain A4G23_RS11500 06532dcd04cdfc70c6652fbc34d09964 437 SUPERFAMILY SSF55785 15 122 7.15E-19 T 10-11-2016 IPR000014 PAS domain A4G23_RS11500 06532dcd04cdfc70c6652fbc34d09964 437 Gene3D G3DSA:3.30.450.40 276 433 2.9E-15 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS11500 06532dcd04cdfc70c6652fbc34d09964 437 Pfam PF01590 GAF domain 346 432 5.5E-5 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS11500 06532dcd04cdfc70c6652fbc34d09964 437 SUPERFAMILY SSF55785 128 234 6.28E-11 T 10-11-2016 IPR000014 PAS domain A4G23_RS11500 06532dcd04cdfc70c6652fbc34d09964 437 SUPERFAMILY SSF55781 304 433 7.06E-8 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS11500 06532dcd04cdfc70c6652fbc34d09964 437 Gene3D G3DSA:3.30.450.20 130 257 8.7E-15 T 10-11-2016 A4G23_RS11500 06532dcd04cdfc70c6652fbc34d09964 437 Pfam PF08448 PAS fold 146 259 7.9E-11 T 10-11-2016 IPR013656 PAS fold-4 A4G23_RS11500 06532dcd04cdfc70c6652fbc34d09964 437 Pfam PF08448 PAS fold 20 127 3.4E-10 T 10-11-2016 IPR013656 PAS fold-4 A4G23_RS00810 478f9415d3ad5f083078eb2c0c25cdb5 506 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 178 486 24.815 T 10-11-2016 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 A4G23_RS00810 478f9415d3ad5f083078eb2c0c25cdb5 506 SUPERFAMILY SSF53335 206 477 2.81E-61 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS00810 478f9415d3ad5f083078eb2c0c25cdb5 506 Pfam PF01564 Spermine/spermidine synthase 220 442 1.6E-37 T 10-11-2016 A4G23_RS00810 478f9415d3ad5f083078eb2c0c25cdb5 506 Gene3D G3DSA:1.20.1250.20 2 186 1.6E-10 T 10-11-2016 A4G23_RS00810 478f9415d3ad5f083078eb2c0c25cdb5 506 Gene3D G3DSA:3.40.50.150 266 479 3.2E-66 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS00810 478f9415d3ad5f083078eb2c0c25cdb5 506 SUPERFAMILY SSF103473 2 187 5.1E-8 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS14885 d6c138a1beb553aa78e04ddae59d2f4c 435 Gene3D G3DSA:3.20.20.370 161 374 2.6E-7 T 10-11-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 A4G23_RS14885 d6c138a1beb553aa78e04ddae59d2f4c 435 SUPERFAMILY SSF88713 97 118 3.89E-21 T 10-11-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A4G23_RS14885 d6c138a1beb553aa78e04ddae59d2f4c 435 SUPERFAMILY SSF88713 148 374 3.89E-21 T 10-11-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A4G23_RS10025 30c4f5e81ca3f930aa34ded179bb2412 629 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 230 393 1.1E-37 T 10-11-2016 IPR004474 Cell envelope-related transcriptional attenuator domain A4G23_RS10025 30c4f5e81ca3f930aa34ded179bb2412 629 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 230 393 1.4E-43 T 10-11-2016 IPR004474 Cell envelope-related transcriptional attenuator domain A4G23_RS10025 30c4f5e81ca3f930aa34ded179bb2412 629 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 511 602 6.7E-12 T 10-11-2016 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain A4G23_RS04785 9fbb84fb0a261c2b41618a1a19083def 576 Gene3D G3DSA:1.20.210.10 17 546 1.1E-191 T 10-11-2016 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS04785 9fbb84fb0a261c2b41618a1a19083def 576 SUPERFAMILY SSF81442 23 533 2.49E-173 T 10-11-2016 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS04785 9fbb84fb0a261c2b41618a1a19083def 576 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 34 478 1.7E-143 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS04785 9fbb84fb0a261c2b41618a1a19083def 576 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 26 531 1.3E-210 T 10-11-2016 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 A4G23_RS04785 9fbb84fb0a261c2b41618a1a19083def 576 PRINTS PR01165 Cytochrome c oxidase subunit I signature 99 123 1.0E-95 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS04785 9fbb84fb0a261c2b41618a1a19083def 576 PRINTS PR01165 Cytochrome c oxidase subunit I signature 299 314 1.0E-95 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS04785 9fbb84fb0a261c2b41618a1a19083def 576 PRINTS PR01165 Cytochrome c oxidase subunit I signature 142 154 1.0E-95 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS04785 9fbb84fb0a261c2b41618a1a19083def 576 PRINTS PR01165 Cytochrome c oxidase subunit I signature 384 403 1.0E-95 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS04785 9fbb84fb0a261c2b41618a1a19083def 576 PRINTS PR01165 Cytochrome c oxidase subunit I signature 25 50 1.0E-95 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS04785 9fbb84fb0a261c2b41618a1a19083def 576 PRINTS PR01165 Cytochrome c oxidase subunit I signature 203 222 1.0E-95 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS04785 9fbb84fb0a261c2b41618a1a19083def 576 PRINTS PR01165 Cytochrome c oxidase subunit I signature 321 342 1.0E-95 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS04785 9fbb84fb0a261c2b41618a1a19083def 576 PRINTS PR01165 Cytochrome c oxidase subunit I signature 253 274 1.0E-95 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS04785 9fbb84fb0a261c2b41618a1a19083def 576 PRINTS PR01165 Cytochrome c oxidase subunit I signature 232 253 1.0E-95 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS04785 9fbb84fb0a261c2b41618a1a19083def 576 PRINTS PR01165 Cytochrome c oxidase subunit I signature 72 95 1.0E-95 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS04785 9fbb84fb0a261c2b41618a1a19083def 576 PRINTS PR01165 Cytochrome c oxidase subunit I signature 174 192 1.0E-95 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS04785 9fbb84fb0a261c2b41618a1a19083def 576 PRINTS PR01165 Cytochrome c oxidase subunit I signature 434 455 1.0E-95 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS04785 9fbb84fb0a261c2b41618a1a19083def 576 PRINTS PR01165 Cytochrome c oxidase subunit I signature 356 374 1.0E-95 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS04785 9fbb84fb0a261c2b41618a1a19083def 576 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 255 309 - T 10-11-2016 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS24980 a01fc586abc74963df99f4ad5300da34 554 Pfam PF03814 Potassium-transporting ATPase A subunit 14 552 1.8E-222 T 10-11-2016 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 A4G23_RS24980 a01fc586abc74963df99f4ad5300da34 554 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 8 553 4.9E-200 T 10-11-2016 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 A4G23_RS24980 a01fc586abc74963df99f4ad5300da34 554 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 4 554 32.076 T 10-11-2016 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 A4G23_RS24980 a01fc586abc74963df99f4ad5300da34 554 PIRSF PIRSF001294 4 554 6.0E-215 T 10-11-2016 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 A4G23_RS25145 07732c3fe4c1124ee434431c27f6d94f 208 Gene3D G3DSA:3.40.50.300 20 160 1.1E-11 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS25145 07732c3fe4c1124ee434431c27f6d94f 208 SUPERFAMILY SSF52540 20 192 7.77E-20 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS25145 07732c3fe4c1124ee434431c27f6d94f 208 Pfam PF03029 Conserved hypothetical ATP binding protein 25 192 5.8E-27 T 10-11-2016 IPR004130 GPN-loop GTPase A4G23_RS07680 f0bce1bf8b0ee00ae85d16c5d42750cf 408 PRINTS PR00046 Major sigma-70 factor signature 368 383 1.4E-29 T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS07680 f0bce1bf8b0ee00ae85d16c5d42750cf 408 PRINTS PR00046 Major sigma-70 factor signature 383 394 1.4E-29 T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS07680 f0bce1bf8b0ee00ae85d16c5d42750cf 408 PRINTS PR00046 Major sigma-70 factor signature 347 359 1.4E-29 T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS07680 f0bce1bf8b0ee00ae85d16c5d42750cf 408 PRINTS PR00046 Major sigma-70 factor signature 199 212 1.4E-29 T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS07680 f0bce1bf8b0ee00ae85d16c5d42750cf 408 PRINTS PR00046 Major sigma-70 factor signature 223 231 1.4E-29 T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS07680 f0bce1bf8b0ee00ae85d16c5d42750cf 408 Gene3D G3DSA:1.10.10.10 337 408 2.7E-27 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS07680 f0bce1bf8b0ee00ae85d16c5d42750cf 408 Gene3D G3DSA:1.10.10.10 248 299 6.0E-21 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS07680 f0bce1bf8b0ee00ae85d16c5d42750cf 408 SUPERFAMILY SSF88946 109 245 4.97E-52 T 10-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS07680 f0bce1bf8b0ee00ae85d16c5d42750cf 408 SUPERFAMILY SSF88659 305 406 2.43E-27 T 10-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS07680 f0bce1bf8b0ee00ae85d16c5d42750cf 408 Pfam PF04542 Sigma-70 region 2 175 244 2.6E-23 T 10-11-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS07680 f0bce1bf8b0ee00ae85d16c5d42750cf 408 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 171 396 2.4E-37 T 10-11-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS07680 f0bce1bf8b0ee00ae85d16c5d42750cf 408 Pfam PF04539 Sigma-70 region 3 254 330 2.7E-27 T 10-11-2016 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS07680 f0bce1bf8b0ee00ae85d16c5d42750cf 408 Pfam PF04545 Sigma-70, region 4 344 396 2.3E-18 T 10-11-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS07680 f0bce1bf8b0ee00ae85d16c5d42750cf 408 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 199 212 - T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS07680 f0bce1bf8b0ee00ae85d16c5d42750cf 408 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 368 394 - T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS07680 f0bce1bf8b0ee00ae85d16c5d42750cf 408 Gene3D G3DSA:1.10.601.10 94 244 6.9E-63 T 10-11-2016 A4G23_RS07680 f0bce1bf8b0ee00ae85d16c5d42750cf 408 SUPERFAMILY SSF88659 248 321 2.53E-19 T 10-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS07680 f0bce1bf8b0ee00ae85d16c5d42750cf 408 Pfam PF00140 Sigma-70 factor, region 1.2 110 143 1.9E-16 T 10-11-2016 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS21300 f82dd18ffa21cf451055d065b8fbbba7 174 Gene3D G3DSA:2.60.60.30 7 167 3.4E-36 T 10-11-2016 A4G23_RS21300 f82dd18ffa21cf451055d065b8fbbba7 174 Pfam PF02342 TerD domain 5 163 4.1E-16 T 10-11-2016 IPR003325 TerD domain GO:0006950 A4G23_RS05220 e89e17117017525a5591a6563386b931 326 SMART SM00292 243 321 5.6E-4 T 10-11-2016 IPR001357 BRCT domain A4G23_RS05220 e89e17117017525a5591a6563386b931 326 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 244 311 4.0E-7 T 10-11-2016 IPR001357 BRCT domain A4G23_RS05220 e89e17117017525a5591a6563386b931 326 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 21 177 4.4E-26 T 10-11-2016 IPR006054 DNA polymerase III, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4G23_RS05220 e89e17117017525a5591a6563386b931 326 Gene3D G3DSA:3.40.50.10190 245 320 9.8E-13 T 10-11-2016 IPR001357 BRCT domain A4G23_RS05220 e89e17117017525a5591a6563386b931 326 Gene3D G3DSA:3.30.420.10 18 185 3.1E-46 T 10-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 A4G23_RS05220 e89e17117017525a5591a6563386b931 326 Pfam PF00929 Exonuclease 23 175 4.2E-24 T 10-11-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III A4G23_RS05220 e89e17117017525a5591a6563386b931 326 SMART SM00479 20 184 2.8E-35 T 10-11-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III A4G23_RS05220 e89e17117017525a5591a6563386b931 326 SUPERFAMILY SSF53098 16 185 7.6E-44 T 10-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 A4G23_RS05220 e89e17117017525a5591a6563386b931 326 SUPERFAMILY SSF52113 241 318 1.87E-11 T 10-11-2016 IPR001357 BRCT domain A4G23_RS25630 d32c14768f923fa89993a40df6657b2c 107 Gene3D G3DSA:3.20.20.80 18 79 1.3E-19 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS25630 d32c14768f923fa89993a40df6657b2c 107 SUPERFAMILY SSF51445 23 80 4.91E-17 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS25630 d32c14768f923fa89993a40df6657b2c 107 PRINTS PR00110 Alpha-amylase signature 27 44 6.9E-7 T 10-11-2016 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 A4G23_RS25630 d32c14768f923fa89993a40df6657b2c 107 PRINTS PR00110 Alpha-amylase signature 59 70 6.9E-7 T 10-11-2016 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 A4G23_RS25630 d32c14768f923fa89993a40df6657b2c 107 Pfam PF00128 Alpha amylase, catalytic domain 40 76 5.6E-6 T 10-11-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A4G23_RS25840 da48b4cf3b8f99edf989975580dab6d2 649 SUPERFAMILY SSF46977 505 648 3.01E-40 T 10-11-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4G23_RS25840 da48b4cf3b8f99edf989975580dab6d2 649 Gene3D G3DSA:3.90.700.10 278 407 4.4E-19 T 10-11-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4G23_RS25840 da48b4cf3b8f99edf989975580dab6d2 649 Gene3D G3DSA:3.50.50.60 409 461 1.7E-77 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS25840 da48b4cf3b8f99edf989975580dab6d2 649 Gene3D G3DSA:3.50.50.60 37 277 1.7E-77 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS25840 da48b4cf3b8f99edf989975580dab6d2 649 Gene3D G3DSA:1.20.58.100 487 603 4.7E-32 T 10-11-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4G23_RS25840 da48b4cf3b8f99edf989975580dab6d2 649 Pfam PF00890 FAD binding domain 47 452 5.9E-61 T 10-11-2016 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4G23_RS25840 da48b4cf3b8f99edf989975580dab6d2 649 TIGRFAM TIGR01811 sdhA_Bsu: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 47 648 0.0 T 10-11-2016 IPR011280 Succinate dehydrogenase/fumarate reductase flavoprotein subunit, low-GC Gram-positive bacteria KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279 A4G23_RS25840 da48b4cf3b8f99edf989975580dab6d2 649 SUPERFAMILY SSF51905 417 462 5.93E-51 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS25840 da48b4cf3b8f99edf989975580dab6d2 649 SUPERFAMILY SSF51905 40 288 5.93E-51 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS25840 da48b4cf3b8f99edf989975580dab6d2 649 SUPERFAMILY SSF56425 272 414 2.69E-34 T 10-11-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4G23_RS25840 da48b4cf3b8f99edf989975580dab6d2 649 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 416 438 9.1E-7 T 10-11-2016 A4G23_RS25840 da48b4cf3b8f99edf989975580dab6d2 649 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 47 66 9.1E-7 T 10-11-2016 A4G23_RS25840 da48b4cf3b8f99edf989975580dab6d2 649 Pfam PF02910 Fumarate reductase flavoprotein C-term 514 648 2.8E-35 T 10-11-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4G23_RS11715 2bdd3b14523430b4e22459c0b5a0640e 406 SUPERFAMILY SSF69318 145 392 9.42E-32 T 10-11-2016 A4G23_RS11715 2bdd3b14523430b4e22459c0b5a0640e 406 Pfam PF03995 Peptidase inhibitor family I36 31 95 6.5E-21 T 10-11-2016 A4G23_RS11715 2bdd3b14523430b4e22459c0b5a0640e 406 Gene3D G3DSA:2.115.10.10 153 352 3.5E-32 T 10-11-2016 IPR023294 Tachylectin 2 A4G23_RS11715 2bdd3b14523430b4e22459c0b5a0640e 406 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 149 205 3.7E-6 T 10-11-2016 A4G23_RS11715 2bdd3b14523430b4e22459c0b5a0640e 406 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 247 309 1.3E-9 T 10-11-2016 A4G23_RS21745 6e4b07b5f2e6ade59b313bf81bf067cc 203 SUPERFAMILY SSF46689 3 61 1.51E-12 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS21745 6e4b07b5f2e6ade59b313bf81bf067cc 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 49 2.0E-8 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS21745 6e4b07b5f2e6ade59b313bf81bf067cc 203 Gene3D G3DSA:1.10.357.10 3 170 6.0E-27 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS21745 6e4b07b5f2e6ade59b313bf81bf067cc 203 SUPERFAMILY SSF48498 73 168 1.39E-7 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS17720 44058e2db5d136b5cfdac1bbf4f82554 317 SUPERFAMILY SSF46785 8 63 4.36E-8 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS17720 44058e2db5d136b5cfdac1bbf4f82554 317 Pfam PF08279 HTH domain 9 64 3.0E-13 T 10-11-2016 IPR013196 Helix-turn-helix, type 11 A4G23_RS17720 44058e2db5d136b5cfdac1bbf4f82554 317 Pfam PF13280 WYL domain 143 309 9.3E-24 T 10-11-2016 IPR026881 WYL domain A4G23_RS17720 44058e2db5d136b5cfdac1bbf4f82554 317 Gene3D G3DSA:1.10.10.10 6 67 9.0E-17 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS20055 e7e06054352b66a56d0de095fdc53fad 317 SUPERFAMILY SSF51726 41 313 5.1E-30 T 10-11-2016 A4G23_RS20055 e7e06054352b66a56d0de095fdc53fad 317 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 5 310 2.8E-11 T 10-11-2016 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 A4G23_RS20055 e7e06054352b66a56d0de095fdc53fad 317 Gene3D G3DSA:3.20.20.210 64 314 4.7E-14 T 10-11-2016 A4G23_RS08985 c5c715f5d9cf4182be6a8f673e182410 347 SUPERFAMILY SSF53807 54 340 4.32E-30 T 10-11-2016 A4G23_RS08985 c5c715f5d9cf4182be6a8f673e182410 347 Pfam PF01497 Periplasmic binding protein 90 316 8.6E-16 T 10-11-2016 IPR002491 ABC transporter periplasmic binding domain GO:0005488 A4G23_RS08985 c5c715f5d9cf4182be6a8f673e182410 347 Gene3D G3DSA:3.40.50.1980 53 187 1.2E-10 T 10-11-2016 A4G23_RS08985 c5c715f5d9cf4182be6a8f673e182410 347 Gene3D G3DSA:3.40.50.1980 196 340 7.5E-16 T 10-11-2016 A4G23_RS11680 68e12dd324a33c8f4719f1bede47e20f 157 ProSitePatterns PS00893 Nudix box signature. 36 57 - T 10-11-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A4G23_RS11680 68e12dd324a33c8f4719f1bede47e20f 157 Gene3D G3DSA:3.90.79.10 2 125 4.8E-29 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS11680 68e12dd324a33c8f4719f1bede47e20f 157 Pfam PF00293 NUDIX domain 4 121 8.0E-17 T 10-11-2016 IPR000086 NUDIX hydrolase domain GO:0016787 A4G23_RS11680 68e12dd324a33c8f4719f1bede47e20f 157 PRINTS PR00502 NUDIX hydrolase family signature 31 45 3.0E-6 T 10-11-2016 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A4G23_RS11680 68e12dd324a33c8f4719f1bede47e20f 157 PRINTS PR00502 NUDIX hydrolase family signature 45 60 3.0E-6 T 10-11-2016 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A4G23_RS11680 68e12dd324a33c8f4719f1bede47e20f 157 SUPERFAMILY SSF55811 3 129 1.49E-28 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS12320 37e8145073a940adb5ec7524782faa6d 350 SMART SM00382 89 337 1.6E-4 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS12320 37e8145073a940adb5ec7524782faa6d 350 SUPERFAMILY SSF52540 90 228 1.82E-10 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS12320 37e8145073a940adb5ec7524782faa6d 350 Gene3D G3DSA:3.40.50.300 84 221 9.4E-11 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS12320 37e8145073a940adb5ec7524782faa6d 350 Pfam PF05621 Bacterial TniB protein 85 318 4.9E-28 T 10-11-2016 IPR008868 Bacterial TniB A4G23_RS15510 5aa84a5b6e17cfaf332ccfc7ee9390ac 617 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 612 9.2E-236 T 10-11-2016 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A4G23_RS15510 5aa84a5b6e17cfaf332ccfc7ee9390ac 617 Pfam PF00920 Dehydratase family 35 609 1.8E-214 T 10-11-2016 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A4G23_RS15510 5aa84a5b6e17cfaf332ccfc7ee9390ac 617 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 123 133 - T 10-11-2016 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A4G23_RS15510 5aa84a5b6e17cfaf332ccfc7ee9390ac 617 SUPERFAMILY SSF143975 4 426 1.31E-130 T 10-11-2016 A4G23_RS15510 5aa84a5b6e17cfaf332ccfc7ee9390ac 617 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 612 44.831 T 10-11-2016 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A4G23_RS15510 5aa84a5b6e17cfaf332ccfc7ee9390ac 617 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 515 526 - T 10-11-2016 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A4G23_RS15510 5aa84a5b6e17cfaf332ccfc7ee9390ac 617 SUPERFAMILY SSF52016 427 613 3.37E-62 T 10-11-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel A4G23_RS08980 ec3738980de290f5a97cf6f564e06ba5 386 SUPERFAMILY SSF47203 232 382 9.83E-52 T 10-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4G23_RS08980 ec3738980de290f5a97cf6f564e06ba5 386 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 120 2.8E-38 T 10-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 A4G23_RS08980 ec3738980de290f5a97cf6f564e06ba5 386 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 234 382 5.1E-49 T 10-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4G23_RS08980 ec3738980de290f5a97cf6f564e06ba5 386 Gene3D G3DSA:2.40.110.10 123 222 2.5E-37 T 10-11-2016 A4G23_RS08980 ec3738980de290f5a97cf6f564e06ba5 386 SUPERFAMILY SSF56645 3 247 1.83E-83 T 10-11-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 A4G23_RS08980 ec3738980de290f5a97cf6f564e06ba5 386 Gene3D G3DSA:1.10.540.10 3 121 8.5E-43 T 10-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 A4G23_RS08980 ec3738980de290f5a97cf6f564e06ba5 386 PIRSF PIRSF016578 4 384 1.0E-12 T 10-11-2016 A4G23_RS08980 ec3738980de290f5a97cf6f564e06ba5 386 Gene3D G3DSA:1.20.140.10 223 382 9.2E-66 T 10-11-2016 A4G23_RS08980 ec3738980de290f5a97cf6f564e06ba5 386 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 124 222 1.7E-20 T 10-11-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 A4G23_RS08980 ec3738980de290f5a97cf6f564e06ba5 386 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 341 360 - T 10-11-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A4G23_RS24500 610a2669908a69f4149c47b11c44aa0c 342 Gene3D G3DSA:3.90.180.10 1 172 1.9E-48 T 10-11-2016 IPR011032 GroES-like A4G23_RS24500 610a2669908a69f4149c47b11c44aa0c 342 Hamap MF_00627 L-threonine 3-dehydrogenase [tdh]. 1 340 57.269 T 10-11-2016 IPR004627 L-threonine 3-dehydrogenase GO:0006567|GO:0008270|GO:0008743|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00260+1.1.1.103|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-7378 A4G23_RS24500 610a2669908a69f4149c47b11c44aa0c 342 Pfam PF00107 Zinc-binding dehydrogenase 174 300 2.9E-25 T 10-11-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A4G23_RS24500 610a2669908a69f4149c47b11c44aa0c 342 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 10-11-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 A4G23_RS24500 610a2669908a69f4149c47b11c44aa0c 342 Gene3D G3DSA:3.40.50.720 173 287 4.9E-33 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS24500 610a2669908a69f4149c47b11c44aa0c 342 SUPERFAMILY SSF50129 1 173 4.41E-53 T 10-11-2016 IPR011032 GroES-like A4G23_RS24500 610a2669908a69f4149c47b11c44aa0c 342 TIGRFAM TIGR00692 tdh: L-threonine 3-dehydrogenase 3 340 7.9E-139 T 10-11-2016 IPR004627 L-threonine 3-dehydrogenase GO:0006567|GO:0008270|GO:0008743|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00260+1.1.1.103|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-7378 A4G23_RS24500 610a2669908a69f4149c47b11c44aa0c 342 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 133 3.8E-32 T 10-11-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A4G23_RS24500 610a2669908a69f4149c47b11c44aa0c 342 SUPERFAMILY SSF51735 142 298 5.79E-33 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS01810 8cd9be76aba743da40b8b5ea85814e91 194 Pfam PF16157 Domain of unknown function (DUF4865) 1 180 2.5E-67 T 10-11-2016 IPR032349 Protein of unknown function DUF4865 A4G23_RS24230 db7aa2bda4926ed02c8ae87e61676011 242 Pfam PF02146 Sir2 family 9 190 5.4E-39 T 10-11-2016 IPR003000 Sirtuin family GO:0070403 A4G23_RS24230 db7aa2bda4926ed02c8ae87e61676011 242 Gene3D G3DSA:3.30.1600.10 20 59 4.9E-21 T 10-11-2016 IPR026591 Sirtuin family, catalytic core small domain A4G23_RS24230 db7aa2bda4926ed02c8ae87e61676011 242 Gene3D G3DSA:3.30.1600.10 112 159 4.9E-21 T 10-11-2016 IPR026591 Sirtuin family, catalytic core small domain A4G23_RS24230 db7aa2bda4926ed02c8ae87e61676011 242 SUPERFAMILY SSF52467 4 238 8.88E-68 T 10-11-2016 IPR029035 DHS-like NAD/FAD-binding domain A4G23_RS24230 db7aa2bda4926ed02c8ae87e61676011 242 Gene3D G3DSA:3.40.50.1220 71 111 2.9E-36 T 10-11-2016 IPR029035 DHS-like NAD/FAD-binding domain A4G23_RS24230 db7aa2bda4926ed02c8ae87e61676011 242 Gene3D G3DSA:3.40.50.1220 4 19 2.9E-36 T 10-11-2016 IPR029035 DHS-like NAD/FAD-binding domain A4G23_RS24230 db7aa2bda4926ed02c8ae87e61676011 242 Gene3D G3DSA:3.40.50.1220 166 238 2.9E-36 T 10-11-2016 IPR029035 DHS-like NAD/FAD-binding domain A4G23_RS00925 29ab22b1c84c528d0554c2d32650b28d 312 Pfam PF13649 Methyltransferase domain 79 176 2.4E-14 T 10-11-2016 A4G23_RS00925 29ab22b1c84c528d0554c2d32650b28d 312 Gene3D G3DSA:3.40.50.150 64 247 4.6E-29 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS00925 29ab22b1c84c528d0554c2d32650b28d 312 SUPERFAMILY SSF53335 61 247 3.68E-33 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS18610 d401e16993b024ac44ffaaa55ec192ab 375 Gene3D G3DSA:1.20.58.340 299 375 2.5E-23 T 10-11-2016 A4G23_RS18610 d401e16993b024ac44ffaaa55ec192ab 375 SUPERFAMILY SSF144083 311 372 7.59E-18 T 10-11-2016 A4G23_RS18610 d401e16993b024ac44ffaaa55ec192ab 375 Gene3D G3DSA:3.30.460.20 28 180 1.6E-46 T 10-11-2016 A4G23_RS18610 d401e16993b024ac44ffaaa55ec192ab 375 Gene3D G3DSA:1.20.58.340 181 297 2.8E-39 T 10-11-2016 A4G23_RS18610 d401e16993b024ac44ffaaa55ec192ab 375 SUPERFAMILY SSF143865 34 306 1.18E-63 T 10-11-2016 A4G23_RS18610 d401e16993b024ac44ffaaa55ec192ab 375 Pfam PF01544 CorA-like Mg2+ transporter protein 73 365 5.8E-59 T 10-11-2016 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 A4G23_RS15150 e3ff7415ece8d87e497af7967284e626 549 SUPERFAMILY SSF56672 152 548 3.56E-63 T 10-11-2016 A4G23_RS15150 e3ff7415ece8d87e497af7967284e626 549 Gene3D G3DSA:1.10.150.20 330 470 1.5E-18 T 10-11-2016 A4G23_RS15150 e3ff7415ece8d87e497af7967284e626 549 SMART SM00482 307 508 1.1E-10 T 10-11-2016 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4G23_RS15150 e3ff7415ece8d87e497af7967284e626 549 Pfam PF00476 DNA polymerase family A 237 518 1.9E-26 T 10-11-2016 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4G23_RS15150 e3ff7415ece8d87e497af7967284e626 549 Gene3D G3DSA:3.30.70.370 290 329 1.1E-10 T 10-11-2016 A4G23_RS15150 e3ff7415ece8d87e497af7967284e626 549 Gene3D G3DSA:3.30.70.370 471 544 1.1E-10 T 10-11-2016 A4G23_RS26590 181fe2c14eaea0caf8c49a70c95261bb 448 SUPERFAMILY SSF56281 3 241 7.84E-39 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS26590 181fe2c14eaea0caf8c49a70c95261bb 448 SUPERFAMILY SSF52821 219 345 1.05E-16 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS26590 181fe2c14eaea0caf8c49a70c95261bb 448 SUPERFAMILY SSF52821 352 443 3.01E-20 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS26590 181fe2c14eaea0caf8c49a70c95261bb 448 Gene3D G3DSA:3.60.15.10 15 237 2.7E-48 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS26590 181fe2c14eaea0caf8c49a70c95261bb 448 Pfam PF00753 Metallo-beta-lactamase superfamily 16 180 1.4E-7 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS26590 181fe2c14eaea0caf8c49a70c95261bb 448 Gene3D G3DSA:3.40.250.10 351 441 9.6E-17 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS26590 181fe2c14eaea0caf8c49a70c95261bb 448 Pfam PF00581 Rhodanese-like domain 358 441 6.8E-7 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS26590 181fe2c14eaea0caf8c49a70c95261bb 448 SMART SM00849 13 180 2.3E-15 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS26590 181fe2c14eaea0caf8c49a70c95261bb 448 SMART SM00450 252 349 7.2 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS26590 181fe2c14eaea0caf8c49a70c95261bb 448 SMART SM00450 356 448 2.6E-9 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS26590 181fe2c14eaea0caf8c49a70c95261bb 448 Gene3D G3DSA:3.40.250.10 253 345 7.5E-7 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS20165 dafdb0f6ac3023a66f220acfd31f0fdc 347 Hamap MF_01035 3-isopropylmalate dehydrogenase [leuB]. 5 345 60.627 T 10-11-2016 IPR023698 3-isopropylmalate dehydrogenase GO:0003862|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 A4G23_RS20165 dafdb0f6ac3023a66f220acfd31f0fdc 347 SUPERFAMILY SSF53659 4 342 7.49E-110 T 10-11-2016 A4G23_RS20165 dafdb0f6ac3023a66f220acfd31f0fdc 347 Gene3D G3DSA:3.40.718.10 5 335 7.1E-114 T 10-11-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A4G23_RS20165 dafdb0f6ac3023a66f220acfd31f0fdc 347 SMART SM01329 6 341 5.2E-165 T 10-11-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A4G23_RS20165 dafdb0f6ac3023a66f220acfd31f0fdc 347 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 239 258 - T 10-11-2016 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 A4G23_RS20165 dafdb0f6ac3023a66f220acfd31f0fdc 347 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 7 326 8.8E-90 T 10-11-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A4G23_RS20250 d60c45e61fa54d87f606c3d91f004c23 173 Gene3D G3DSA:3.40.50.300 2 167 3.9E-11 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS20250 d60c45e61fa54d87f606c3d91f004c23 173 SUPERFAMILY SSF52540 1 170 1.84E-19 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS20250 d60c45e61fa54d87f606c3d91f004c23 173 Pfam PF03029 Conserved hypothetical ATP binding protein 1 168 4.9E-28 T 10-11-2016 IPR004130 GPN-loop GTPase A4G23_RS24245 d3e3069e8e6d9fb1cf780cd0516502c3 571 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 27 513 4.1E-188 T 10-11-2016 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 A4G23_RS24245 d3e3069e8e6d9fb1cf780cd0516502c3 571 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 65 513 3.5E-163 T 10-11-2016 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 A4G23_RS24245 d3e3069e8e6d9fb1cf780cd0516502c3 571 ProSitePatterns PS01303 BCCT family of transporters signature. 331 340 - T 10-11-2016 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 A4G23_RS27040 5b23458f61c50ebb3f04737d266349ea 297 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 168 286 3.6E-16 T 10-11-2016 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 A4G23_RS27040 5b23458f61c50ebb3f04737d266349ea 297 SUPERFAMILY SSF48179 168 287 5.44E-23 T 10-11-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A4G23_RS27040 5b23458f61c50ebb3f04737d266349ea 297 Gene3D G3DSA:3.40.50.720 6 166 1.2E-41 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS27040 5b23458f61c50ebb3f04737d266349ea 297 Gene3D G3DSA:1.10.1040.10 168 286 1.0E-26 T 10-11-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A4G23_RS27040 5b23458f61c50ebb3f04737d266349ea 297 PIRSF PIRSF000103 1 294 4.7E-76 T 10-11-2016 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 A4G23_RS27040 5b23458f61c50ebb3f04737d266349ea 297 SUPERFAMILY SSF51735 5 163 1.91E-36 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS27040 5b23458f61c50ebb3f04737d266349ea 297 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 6 162 2.6E-36 T 10-11-2016 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 A4G23_RS18185 78755ee0aa69dac7b363dd02936e76a0 492 Pfam PF01594 Domain of unknown function DUF20 135 459 3.2E-58 T 10-11-2016 IPR002549 Transmembrane protein TqsA-like A4G23_RS10965 34fc8527a57279bbf325130c35a8b6c6 332 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 293 319 - T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS10965 34fc8527a57279bbf325130c35a8b6c6 332 SUPERFAMILY SSF88659 231 326 4.58E-23 T 10-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS10965 34fc8527a57279bbf325130c35a8b6c6 332 SUPERFAMILY SSF88946 33 170 5.23E-48 T 10-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS10965 34fc8527a57279bbf325130c35a8b6c6 332 PRINTS PR00046 Major sigma-70 factor signature 293 308 4.3E-25 T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS10965 34fc8527a57279bbf325130c35a8b6c6 332 PRINTS PR00046 Major sigma-70 factor signature 148 156 4.3E-25 T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS10965 34fc8527a57279bbf325130c35a8b6c6 332 PRINTS PR00046 Major sigma-70 factor signature 308 319 4.3E-25 T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS10965 34fc8527a57279bbf325130c35a8b6c6 332 PRINTS PR00046 Major sigma-70 factor signature 124 137 4.3E-25 T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS10965 34fc8527a57279bbf325130c35a8b6c6 332 PRINTS PR00046 Major sigma-70 factor signature 272 284 4.3E-25 T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS10965 34fc8527a57279bbf325130c35a8b6c6 332 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 124 137 - T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS10965 34fc8527a57279bbf325130c35a8b6c6 332 Pfam PF04542 Sigma-70 region 2 100 170 6.9E-21 T 10-11-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS10965 34fc8527a57279bbf325130c35a8b6c6 332 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 96 321 2.2E-33 T 10-11-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS10965 34fc8527a57279bbf325130c35a8b6c6 332 SUPERFAMILY SSF88659 173 246 2.09E-15 T 10-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS10965 34fc8527a57279bbf325130c35a8b6c6 332 Pfam PF00140 Sigma-70 factor, region 1.2 33 66 1.8E-10 T 10-11-2016 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS10965 34fc8527a57279bbf325130c35a8b6c6 332 Gene3D G3DSA:1.10.601.10 21 169 3.3E-56 T 10-11-2016 A4G23_RS10965 34fc8527a57279bbf325130c35a8b6c6 332 Pfam PF04545 Sigma-70, region 4 269 320 5.2E-14 T 10-11-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS10965 34fc8527a57279bbf325130c35a8b6c6 332 Gene3D G3DSA:1.10.10.10 173 224 1.1E-16 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS10965 34fc8527a57279bbf325130c35a8b6c6 332 Pfam PF04539 Sigma-70 region 3 179 255 4.4E-23 T 10-11-2016 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS10965 34fc8527a57279bbf325130c35a8b6c6 332 Gene3D G3DSA:1.10.10.10 263 326 9.5E-23 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS09670 ae693a4cd8e4b91beb4345cd3fdc615f 474 SMART SM01274 93 226 3.2E-85 T 10-11-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 A4G23_RS09670 ae693a4cd8e4b91beb4345cd3fdc615f 474 Gene3D G3DSA:3.30.70.260 24 79 4.2E-4 T 10-11-2016 A4G23_RS09670 ae693a4cd8e4b91beb4345cd3fdc615f 474 SUPERFAMILY SSF53223 87 236 4.46E-57 T 10-11-2016 A4G23_RS09670 ae693a4cd8e4b91beb4345cd3fdc615f 474 PIRSF PIRSF000106 75 472 1.0E-80 T 10-11-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 A4G23_RS09670 ae693a4cd8e4b91beb4345cd3fdc615f 474 Gene3D G3DSA:3.40.50.10380 93 235 1.8E-55 T 10-11-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 A4G23_RS09670 ae693a4cd8e4b91beb4345cd3fdc615f 474 SMART SM00919 238 465 2.9E-105 T 10-11-2016 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 A4G23_RS09670 ae693a4cd8e4b91beb4345cd3fdc615f 474 Gene3D G3DSA:3.40.50.720 236 464 1.6E-68 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS09670 ae693a4cd8e4b91beb4345cd3fdc615f 474 SUPERFAMILY SSF51735 238 465 5.36E-65 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS09670 ae693a4cd8e4b91beb4345cd3fdc615f 474 Pfam PF00390 Malic enzyme, N-terminal domain 94 226 6.1E-31 T 10-11-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 A4G23_RS09670 ae693a4cd8e4b91beb4345cd3fdc615f 474 PRINTS PR00072 Malic enzyme signature 155 177 9.0E-12 T 10-11-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 A4G23_RS09670 ae693a4cd8e4b91beb4345cd3fdc615f 474 PRINTS PR00072 Malic enzyme signature 265 281 9.0E-12 T 10-11-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 A4G23_RS09670 ae693a4cd8e4b91beb4345cd3fdc615f 474 PRINTS PR00072 Malic enzyme signature 358 374 9.0E-12 T 10-11-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 A4G23_RS09670 ae693a4cd8e4b91beb4345cd3fdc615f 474 PRINTS PR00072 Malic enzyme signature 234 250 9.0E-12 T 10-11-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 A4G23_RS09670 ae693a4cd8e4b91beb4345cd3fdc615f 474 Pfam PF03949 Malic enzyme, NAD binding domain 240 462 7.0E-21 T 10-11-2016 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 A4G23_RS03470 169a15c245922bd8f8da59607a30374f 285 SUPERFAMILY SSF88946 23 131 2.04E-30 T 10-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS03470 169a15c245922bd8f8da59607a30374f 285 PRINTS PR00046 Major sigma-70 factor signature 234 246 9.8E-11 T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS03470 169a15c245922bd8f8da59607a30374f 285 PRINTS PR00046 Major sigma-70 factor signature 251 266 9.8E-11 T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS03470 169a15c245922bd8f8da59607a30374f 285 PRINTS PR00046 Major sigma-70 factor signature 86 99 9.8E-11 T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS03470 169a15c245922bd8f8da59607a30374f 285 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 56 281 3.1E-89 T 10-11-2016 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS03470 169a15c245922bd8f8da59607a30374f 285 Gene3D G3DSA:1.10.601.10 46 129 3.1E-24 T 10-11-2016 A4G23_RS03470 169a15c245922bd8f8da59607a30374f 285 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 59 279 4.9E-33 T 10-11-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS03470 169a15c245922bd8f8da59607a30374f 285 SUPERFAMILY SSF88659 135 212 7.41E-16 T 10-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS03470 169a15c245922bd8f8da59607a30374f 285 Gene3D G3DSA:1.10.10.10 226 281 2.1E-10 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS03470 169a15c245922bd8f8da59607a30374f 285 PIRSF PIRSF000770 34 285 2.9E-34 T 10-11-2016 IPR016263 RNA polymerase sporulation-specific sigma factor GO:0003677|GO:0006351|GO:0016987|GO:0030435 A4G23_RS03470 169a15c245922bd8f8da59607a30374f 285 Pfam PF04542 Sigma-70 region 2 62 131 6.1E-16 T 10-11-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS03470 169a15c245922bd8f8da59607a30374f 285 SUPERFAMILY SSF88659 204 281 3.92E-16 T 10-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS03470 169a15c245922bd8f8da59607a30374f 285 Pfam PF04539 Sigma-70 region 3 141 204 4.6E-13 T 10-11-2016 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS03470 169a15c245922bd8f8da59607a30374f 285 Gene3D G3DSA:1.10.10.10 130 185 6.9E-23 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS03470 169a15c245922bd8f8da59607a30374f 285 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 86 99 - T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS03470 169a15c245922bd8f8da59607a30374f 285 Pfam PF04545 Sigma-70, region 4 230 279 3.9E-17 T 10-11-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS10660 48a8bb70a97b75d7f4a092fcf92ec522 285 Gene3D G3DSA:1.10.8.100 221 283 3.7E-21 T 10-11-2016 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201 A4G23_RS10660 48a8bb70a97b75d7f4a092fcf92ec522 285 SMART SM00650 40 214 1.2E-69 T 10-11-2016 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 A4G23_RS10660 48a8bb70a97b75d7f4a092fcf92ec522 285 Pfam PF00398 Ribosomal RNA adenine dimethylase 28 282 1.8E-44 T 10-11-2016 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm A4G23_RS10660 48a8bb70a97b75d7f4a092fcf92ec522 285 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 24 282 1.5E-71 T 10-11-2016 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 A4G23_RS10660 48a8bb70a97b75d7f4a092fcf92ec522 285 Gene3D G3DSA:3.40.50.150 11 215 4.2E-67 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS10660 48a8bb70a97b75d7f4a092fcf92ec522 285 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 56 83 - T 10-11-2016 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 A4G23_RS10660 48a8bb70a97b75d7f4a092fcf92ec522 285 SUPERFAMILY SSF53335 24 283 1.07E-64 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS10660 48a8bb70a97b75d7f4a092fcf92ec522 285 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 24 285 48.689 T 10-11-2016 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 A4G23_RS11120 20f369bd1db2dd409eda7efa6b2888d3 373 Pfam PF03747 ADP-ribosylglycohydrolase 23 327 8.9E-51 T 10-11-2016 IPR005502 ADP-ribosylation/Crystallin J1 A4G23_RS11120 20f369bd1db2dd409eda7efa6b2888d3 373 SUPERFAMILY SSF101478 16 348 2.09E-51 T 10-11-2016 IPR005502 ADP-ribosylation/Crystallin J1 A4G23_RS24320 4f436ce70d987e5a422e47d640b58622 530 Gene3D G3DSA:3.40.50.1820 52 136 2.4E-58 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS24320 4f436ce70d987e5a422e47d640b58622 530 Gene3D G3DSA:3.40.50.1820 357 477 2.4E-58 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS24320 4f436ce70d987e5a422e47d640b58622 530 Gene3D G3DSA:3.40.50.1820 179 303 2.4E-58 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS24320 4f436ce70d987e5a422e47d640b58622 530 SUPERFAMILY SSF53474 322 337 8.27E-26 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS24320 4f436ce70d987e5a422e47d640b58622 530 SUPERFAMILY SSF53474 66 131 8.27E-26 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS24320 4f436ce70d987e5a422e47d640b58622 530 SUPERFAMILY SSF53474 412 462 8.27E-26 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS24320 4f436ce70d987e5a422e47d640b58622 530 SUPERFAMILY SSF53474 169 234 8.27E-26 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS24320 4f436ce70d987e5a422e47d640b58622 530 Pfam PF00561 alpha/beta hydrolase fold 86 459 9.8E-33 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS05200 788e651e7bc9d94f492781acec1861a5 420 Pfam PF02515 CoA-transferase family III 165 368 4.4E-50 T 10-11-2016 IPR003673 CoA-transferase family III GO:0003824 A4G23_RS05200 788e651e7bc9d94f492781acec1861a5 420 Gene3D G3DSA:3.40.50.10540 25 91 5.0E-4 T 10-11-2016 IPR023606 CoA-transferase family III domain A4G23_RS05200 788e651e7bc9d94f492781acec1861a5 420 SUPERFAMILY SSF89796 163 358 1.44E-57 T 10-11-2016 IPR023606 CoA-transferase family III domain A4G23_RS05200 788e651e7bc9d94f492781acec1861a5 420 Gene3D G3DSA:3.40.50.10540 163 354 1.8E-68 T 10-11-2016 IPR023606 CoA-transferase family III domain A4G23_RS05200 788e651e7bc9d94f492781acec1861a5 420 SUPERFAMILY SSF89796 21 133 6.67E-17 T 10-11-2016 IPR023606 CoA-transferase family III domain A4G23_RS25370 bf5f64532dbeee06792edc4f2a146dcc 311 Pfam PF07728 AAA domain (dynein-related subfamily) 57 176 7.9E-5 T 10-11-2016 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 A4G23_RS25370 bf5f64532dbeee06792edc4f2a146dcc 311 SUPERFAMILY SSF52540 30 256 1.09E-26 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS25370 bf5f64532dbeee06792edc4f2a146dcc 311 SMART SM00382 54 237 6.8E-9 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS25370 bf5f64532dbeee06792edc4f2a146dcc 311 Gene3D G3DSA:3.40.50.300 32 248 4.0E-21 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS21175 2a044e57ea9de7e7224bba62ff54aa29 376 PRINTS PR00142 RecA protein signature 128 157 1.5E-85 T 10-11-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A4G23_RS21175 2a044e57ea9de7e7224bba62ff54aa29 376 PRINTS PR00142 RecA protein signature 94 123 1.5E-85 T 10-11-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A4G23_RS21175 2a044e57ea9de7e7224bba62ff54aa29 376 PRINTS PR00142 RecA protein signature 166 195 1.5E-85 T 10-11-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A4G23_RS21175 2a044e57ea9de7e7224bba62ff54aa29 376 PRINTS PR00142 RecA protein signature 244 273 1.5E-85 T 10-11-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A4G23_RS21175 2a044e57ea9de7e7224bba62ff54aa29 376 PRINTS PR00142 RecA protein signature 211 239 1.5E-85 T 10-11-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A4G23_RS21175 2a044e57ea9de7e7224bba62ff54aa29 376 PRINTS PR00142 RecA protein signature 298 315 1.5E-85 T 10-11-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A4G23_RS21175 2a044e57ea9de7e7224bba62ff54aa29 376 Pfam PF00154 recA bacterial DNA recombination protein 8 269 3.3E-144 T 10-11-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A4G23_RS21175 2a044e57ea9de7e7224bba62ff54aa29 376 SMART SM00382 58 229 5.2E-12 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS21175 2a044e57ea9de7e7224bba62ff54aa29 376 Gene3D G3DSA:3.30.250.10 269 327 9.5E-29 T 10-11-2016 IPR023400 DNA recombination and repair protein RecA, C-terminal A4G23_RS21175 2a044e57ea9de7e7224bba62ff54aa29 376 Gene3D G3DSA:3.40.50.300 28 268 5.6E-89 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS21175 2a044e57ea9de7e7224bba62ff54aa29 376 Hamap MF_00268 Protein RecA [recA]. 6 330 52.803 T 10-11-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A4G23_RS21175 2a044e57ea9de7e7224bba62ff54aa29 376 SUPERFAMILY SSF54752 269 326 7.19E-21 T 10-11-2016 IPR023400 DNA recombination and repair protein RecA, C-terminal A4G23_RS21175 2a044e57ea9de7e7224bba62ff54aa29 376 ProSitePatterns PS00321 recA signature. 214 222 - T 10-11-2016 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 A4G23_RS21175 2a044e57ea9de7e7224bba62ff54aa29 376 SUPERFAMILY SSF52540 5 268 1.44E-70 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS21175 2a044e57ea9de7e7224bba62ff54aa29 376 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 5 324 2.3E-176 T 10-11-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A4G23_RS01200 d81d1b7dc0e0a41af26153c029e96a96 243 SUPERFAMILY SSF53474 5 235 1.17E-44 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS01200 d81d1b7dc0e0a41af26153c029e96a96 243 Pfam PF12697 Alpha/beta hydrolase family 9 230 4.5E-21 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS01200 d81d1b7dc0e0a41af26153c029e96a96 243 PRINTS PR00111 Alpha/beta hydrolase fold signature 183 197 3.3E-10 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS01200 d81d1b7dc0e0a41af26153c029e96a96 243 PRINTS PR00111 Alpha/beta hydrolase fold signature 32 47 3.3E-10 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS01200 d81d1b7dc0e0a41af26153c029e96a96 243 PRINTS PR00111 Alpha/beta hydrolase fold signature 74 87 3.3E-10 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS01200 d81d1b7dc0e0a41af26153c029e96a96 243 PRINTS PR00111 Alpha/beta hydrolase fold signature 88 101 3.3E-10 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS01200 d81d1b7dc0e0a41af26153c029e96a96 243 Gene3D G3DSA:3.40.50.1820 6 235 7.9E-44 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS16200 76ff3b5bbc72a16920b8f1bc6016f737 322 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 3 321 22.388 T 10-11-2016 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16200 76ff3b5bbc72a16920b8f1bc6016f737 322 Pfam PF00146 NADH dehydrogenase 11 314 4.7E-100 T 10-11-2016 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS00380 ac7ec66129616cad876d7e8203774e0c 71 SUPERFAMILY SSF47413 2 68 3.44E-16 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS00380 ac7ec66129616cad876d7e8203774e0c 71 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 8 68 4.3E-20 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS00380 ac7ec66129616cad876d7e8203774e0c 71 SMART SM00530 6 62 2.8E-5 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS00380 ac7ec66129616cad876d7e8203774e0c 71 Gene3D G3DSA:1.10.260.40 7 69 9.7E-15 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS18045 019dfe6c7cde709a6d94ab62831166df 533 Gene3D G3DSA:3.20.20.140 78 298 2.8E-112 T 10-11-2016 A4G23_RS18045 019dfe6c7cde709a6d94ab62831166df 533 Gene3D G3DSA:3.20.20.140 394 454 2.8E-112 T 10-11-2016 A4G23_RS18045 019dfe6c7cde709a6d94ab62831166df 533 Pfam PF07969 Amidohydrolase family 53 514 2.2E-52 T 10-11-2016 IPR013108 Amidohydrolase 3 A4G23_RS18045 019dfe6c7cde709a6d94ab62831166df 533 SUPERFAMILY SSF51338 2 64 1.37E-18 T 10-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4G23_RS18045 019dfe6c7cde709a6d94ab62831166df 533 SUPERFAMILY SSF51338 470 521 1.37E-18 T 10-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4G23_RS18045 019dfe6c7cde709a6d94ab62831166df 533 Gene3D G3DSA:2.30.40.10 455 520 1.6E-11 T 10-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4G23_RS18045 019dfe6c7cde709a6d94ab62831166df 533 SUPERFAMILY SSF51556 349 470 5.72E-71 T 10-11-2016 IPR032466 Metal-dependent hydrolase A4G23_RS18045 019dfe6c7cde709a6d94ab62831166df 533 SUPERFAMILY SSF51556 64 306 5.72E-71 T 10-11-2016 IPR032466 Metal-dependent hydrolase A4G23_RS18045 019dfe6c7cde709a6d94ab62831166df 533 Gene3D G3DSA:2.30.40.10 2 77 5.9E-15 T 10-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4G23_RS25900 1dbb28219eadc951f9f8ec8889042363 274 TIGRFAM TIGR02452 TIGR02452: TIGR02452 family protein 7 268 3.6E-97 T 10-11-2016 IPR012664 Conserved hypothetical protein CHP02452 A4G23_RS25900 1dbb28219eadc951f9f8ec8889042363 274 Pfam PF10021 Uncharacterized protein conserved in bacteria (DUF2263) 9 153 3.5E-48 T 10-11-2016 IPR019261 Domain of unknown function DUF2263 A4G23_RS25900 1dbb28219eadc951f9f8ec8889042363 274 SUPERFAMILY SSF52949 190 266 2.59E-6 T 10-11-2016 A4G23_RS25900 1dbb28219eadc951f9f8ec8889042363 274 PIRSF PIRSF014899 1 274 4.2E-117 T 10-11-2016 IPR012664 Conserved hypothetical protein CHP02452 A4G23_RS08290 b634984035a685761d5e3625ede96462 873 Pfam PF08264 Anticodon-binding domain of tRNA 612 753 6.6E-37 T 10-11-2016 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 A4G23_RS08290 b634984035a685761d5e3625ede96462 873 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 56 67 - T 10-11-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4G23_RS08290 b634984035a685761d5e3625ede96462 873 Gene3D G3DSA:3.90.740.10 176 354 6.9E-59 T 10-11-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A4G23_RS08290 b634984035a685761d5e3625ede96462 873 SUPERFAMILY SSF46589 806 870 9.94E-15 T 10-11-2016 IPR010978 tRNA-binding arm GO:0000166 A4G23_RS08290 b634984035a685761d5e3625ede96462 873 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 28 566 1.4E-188 T 10-11-2016 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4G23_RS08290 b634984035a685761d5e3625ede96462 873 SUPERFAMILY SSF52374 351 580 3.47E-134 T 10-11-2016 A4G23_RS08290 b634984035a685761d5e3625ede96462 873 SUPERFAMILY SSF52374 13 203 3.47E-134 T 10-11-2016 A4G23_RS08290 b634984035a685761d5e3625ede96462 873 SUPERFAMILY SSF47323 582 819 4.49E-50 T 10-11-2016 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4G23_RS08290 b634984035a685761d5e3625ede96462 873 SUPERFAMILY SSF50677 205 344 7.19E-53 T 10-11-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A4G23_RS08290 b634984035a685761d5e3625ede96462 873 TIGRFAM TIGR00422 valS: valine--tRNA ligase 16 851 0.0 T 10-11-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A4G23_RS08290 b634984035a685761d5e3625ede96462 873 Hamap MF_02004 Valine--tRNA ligase [valS]. 15 871 15.154 T 10-11-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A4G23_RS08290 b634984035a685761d5e3625ede96462 873 Gene3D G3DSA:3.40.50.620 38 175 8.1E-108 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS08290 b634984035a685761d5e3625ede96462 873 Gene3D G3DSA:3.40.50.620 356 522 8.1E-108 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS08290 b634984035a685761d5e3625ede96462 873 PRINTS PR00986 Valyl-tRNA synthetase signature 356 369 1.3E-37 T 10-11-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A4G23_RS08290 b634984035a685761d5e3625ede96462 873 PRINTS PR00986 Valyl-tRNA synthetase signature 481 499 1.3E-37 T 10-11-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A4G23_RS08290 b634984035a685761d5e3625ede96462 873 PRINTS PR00986 Valyl-tRNA synthetase signature 241 258 1.3E-37 T 10-11-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A4G23_RS08290 b634984035a685761d5e3625ede96462 873 PRINTS PR00986 Valyl-tRNA synthetase signature 450 471 1.3E-37 T 10-11-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A4G23_RS08290 b634984035a685761d5e3625ede96462 873 PRINTS PR00986 Valyl-tRNA synthetase signature 49 60 1.3E-37 T 10-11-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A4G23_RS08290 b634984035a685761d5e3625ede96462 873 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 806 870 5.7E-17 T 10-11-2016 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 A4G23_RS08290 b634984035a685761d5e3625ede96462 873 Gene3D G3DSA:1.10.730.10 523 746 1.1E-70 T 10-11-2016 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4G23_RS08290 b634984035a685761d5e3625ede96462 873 Gene3D G3DSA:1.10.287.380 799 870 1.6E-9 T 10-11-2016 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 A4G23_RS18170 2c96888bc2e9831fcf47393772b79ea9 253 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 24 252 6.7E-64 T 10-11-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A4G23_RS18170 2c96888bc2e9831fcf47393772b79ea9 253 SUPERFAMILY SSF64005 19 247 1.31E-73 T 10-11-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A4G23_RS18170 2c96888bc2e9831fcf47393772b79ea9 253 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 24 253 35.326 T 10-11-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A4G23_RS18170 2c96888bc2e9831fcf47393772b79ea9 253 Gene3D G3DSA:3.40.1180.10 10 252 4.4E-86 T 10-11-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A4G23_RS18170 2c96888bc2e9831fcf47393772b79ea9 253 Pfam PF01255 Putative undecaprenyl diphosphate synthase 31 252 1.4E-69 T 10-11-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A4G23_RS18170 2c96888bc2e9831fcf47393772b79ea9 253 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 198 215 - T 10-11-2016 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 A4G23_RS05425 611cefd8f3d05cdbeaeaf10613f6fd2d 274 SUPERFAMILY SSF52266 36 245 2.83E-49 T 10-11-2016 IPR013830 SGNH hydrolase-type esterase domain A4G23_RS05425 611cefd8f3d05cdbeaeaf10613f6fd2d 274 Gene3D G3DSA:3.40.50.1110 36 246 5.5E-69 T 10-11-2016 IPR013830 SGNH hydrolase-type esterase domain A4G23_RS05425 611cefd8f3d05cdbeaeaf10613f6fd2d 274 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 40 233 1.1E-16 T 10-11-2016 IPR013830 SGNH hydrolase-type esterase domain A4G23_RS23330 87f7c67075fc6eb614be8634f66c30c7 251 Gene3D G3DSA:1.20.120.530 117 250 8.5E-22 T 10-11-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal A4G23_RS23330 87f7c67075fc6eb614be8634f66c30c7 251 SUPERFAMILY SSF48008 119 250 1.7E-21 T 10-11-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal A4G23_RS23330 87f7c67075fc6eb614be8634f66c30c7 251 SUPERFAMILY SSF46785 47 117 2.72E-15 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS23330 87f7c67075fc6eb614be8634f66c30c7 251 Pfam PF07729 FCD domain 123 246 4.9E-21 T 10-11-2016 IPR011711 GntR, C-terminal A4G23_RS23330 87f7c67075fc6eb614be8634f66c30c7 251 SMART SM00345 55 113 2.1E-9 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS23330 87f7c67075fc6eb614be8634f66c30c7 251 SMART SM00895 123 248 1.7E-14 T 10-11-2016 IPR011711 GntR, C-terminal A4G23_RS23330 87f7c67075fc6eb614be8634f66c30c7 251 Gene3D G3DSA:1.10.10.10 42 113 3.8E-20 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS23330 87f7c67075fc6eb614be8634f66c30c7 251 Pfam PF00392 Bacterial regulatory proteins, gntR family 54 113 7.6E-13 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS13080 bdd4f770ed3e9bd6a982eed5ce74a441 353 Pfam PF01594 Domain of unknown function DUF20 27 336 6.7E-55 T 10-11-2016 IPR002549 Transmembrane protein TqsA-like A4G23_RS06270 c08848981f10d3a2f02dda3dd1841f1a 681 Pfam PF03717 Penicillin-binding Protein dimerisation domain 117 287 1.0E-13 T 10-11-2016 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 A4G23_RS06270 c08848981f10d3a2f02dda3dd1841f1a 681 SUPERFAMILY SSF56601 260 664 8.54E-87 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS06270 c08848981f10d3a2f02dda3dd1841f1a 681 Pfam PF00905 Penicillin binding protein transpeptidase domain 333 648 1.8E-72 T 10-11-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A4G23_RS06270 c08848981f10d3a2f02dda3dd1841f1a 681 Gene3D G3DSA:3.90.1310.10 228 314 1.5E-24 T 10-11-2016 A4G23_RS06270 c08848981f10d3a2f02dda3dd1841f1a 681 Gene3D G3DSA:3.40.710.10 315 652 4.8E-90 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS06270 c08848981f10d3a2f02dda3dd1841f1a 681 SUPERFAMILY SSF56519 116 307 2.75E-31 T 10-11-2016 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 A4G23_RS25875 44c8ef1e2bc70bb370452ed40147ff19 311 Pfam PF01553 Acyltransferase 76 197 3.2E-20 T 10-11-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 A4G23_RS25875 44c8ef1e2bc70bb370452ed40147ff19 311 SMART SM00563 88 200 5.2E-34 T 10-11-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 A4G23_RS25875 44c8ef1e2bc70bb370452ed40147ff19 311 Gene3D G3DSA:3.40.1130.10 86 197 3.3E-9 T 10-11-2016 A4G23_RS25875 44c8ef1e2bc70bb370452ed40147ff19 311 SUPERFAMILY SSF69593 47 204 5.89E-29 T 10-11-2016 A4G23_RS25570 3e1913d0adf73df0e7e2761d9a50da3a 889 SUPERFAMILY SSF81665 659 887 3.4E-103 T 10-11-2016 A4G23_RS25570 3e1913d0adf73df0e7e2761d9a50da3a 889 SUPERFAMILY SSF81665 233 326 3.4E-103 T 10-11-2016 A4G23_RS25570 3e1913d0adf73df0e7e2761d9a50da3a 889 SUPERFAMILY SSF81665 18 124 3.4E-103 T 10-11-2016 A4G23_RS25570 3e1913d0adf73df0e7e2761d9a50da3a 889 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 641 666 2.8E-13 T 10-11-2016 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A4G23_RS25570 3e1913d0adf73df0e7e2761d9a50da3a 889 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 609 625 2.8E-13 T 10-11-2016 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A4G23_RS25570 3e1913d0adf73df0e7e2761d9a50da3a 889 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 463 481 2.8E-13 T 10-11-2016 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A4G23_RS25570 3e1913d0adf73df0e7e2761d9a50da3a 889 Pfam PF00689 Cation transporting ATPase, C-terminus 695 881 3.8E-43 T 10-11-2016 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 A4G23_RS25570 3e1913d0adf73df0e7e2761d9a50da3a 889 SUPERFAMILY SSF81653 123 230 5.23E-26 T 10-11-2016 A4G23_RS25570 3e1913d0adf73df0e7e2761d9a50da3a 889 Pfam PF00690 Cation transporter/ATPase, N-terminus 17 80 3.1E-15 T 10-11-2016 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 A4G23_RS25570 3e1913d0adf73df0e7e2761d9a50da3a 889 Pfam PF00122 E1-E2 ATPase 93 323 2.4E-61 T 10-11-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 A4G23_RS25570 3e1913d0adf73df0e7e2761d9a50da3a 889 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 234 372 1.6E-20 T 10-11-2016 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A4G23_RS25570 3e1913d0adf73df0e7e2761d9a50da3a 889 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 583 690 3.0E-29 T 10-11-2016 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A4G23_RS25570 3e1913d0adf73df0e7e2761d9a50da3a 889 SUPERFAMILY SSF56784 460 715 1.92E-54 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS25570 3e1913d0adf73df0e7e2761d9a50da3a 889 SUPERFAMILY SSF56784 330 350 1.92E-54 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS25570 3e1913d0adf73df0e7e2761d9a50da3a 889 SMART SM00831 13 86 1.1E-12 T 10-11-2016 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 A4G23_RS25570 3e1913d0adf73df0e7e2761d9a50da3a 889 Pfam PF00702 haloacid dehalogenase-like hydrolase 329 622 3.6E-22 T 10-11-2016 A4G23_RS25570 3e1913d0adf73df0e7e2761d9a50da3a 889 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 505 516 8.6E-37 T 10-11-2016 A4G23_RS25570 3e1913d0adf73df0e7e2761d9a50da3a 889 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 609 628 8.6E-37 T 10-11-2016 A4G23_RS25570 3e1913d0adf73df0e7e2761d9a50da3a 889 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 170 184 8.6E-37 T 10-11-2016 A4G23_RS25570 3e1913d0adf73df0e7e2761d9a50da3a 889 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 633 645 8.6E-37 T 10-11-2016 A4G23_RS25570 3e1913d0adf73df0e7e2761d9a50da3a 889 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 332 346 8.6E-37 T 10-11-2016 A4G23_RS25570 3e1913d0adf73df0e7e2761d9a50da3a 889 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 527 537 8.6E-37 T 10-11-2016 A4G23_RS25570 3e1913d0adf73df0e7e2761d9a50da3a 889 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 334 340 - T 10-11-2016 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 A4G23_RS25570 3e1913d0adf73df0e7e2761d9a50da3a 889 Gene3D G3DSA:2.70.150.10 31 65 2.9E-35 T 10-11-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 A4G23_RS25570 3e1913d0adf73df0e7e2761d9a50da3a 889 Gene3D G3DSA:2.70.150.10 119 230 2.9E-35 T 10-11-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 A4G23_RS25570 3e1913d0adf73df0e7e2761d9a50da3a 889 Gene3D G3DSA:3.40.1110.10 322 512 4.8E-35 T 10-11-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A4G23_RS25570 3e1913d0adf73df0e7e2761d9a50da3a 889 Gene3D G3DSA:1.20.1110.10 578 884 4.8E-88 T 10-11-2016 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A4G23_RS25570 3e1913d0adf73df0e7e2761d9a50da3a 889 Gene3D G3DSA:1.20.1110.10 66 118 4.8E-88 T 10-11-2016 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A4G23_RS25570 3e1913d0adf73df0e7e2761d9a50da3a 889 SUPERFAMILY SSF81660 339 509 3.24E-27 T 10-11-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A4G23_RS02270 19161b956c6b52e21635fa16ccd594c1 325 PRINTS PR00960 LmbP protein signature 93 114 6.5E-35 T 10-11-2016 IPR001174 Galactokinase/homoserine kinase GO:0005524|GO:0008152|GO:0016301 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478 A4G23_RS02270 19161b956c6b52e21635fa16ccd594c1 325 PRINTS PR00960 LmbP protein signature 6 21 6.5E-35 T 10-11-2016 IPR001174 Galactokinase/homoserine kinase GO:0005524|GO:0008152|GO:0016301 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478 A4G23_RS02270 19161b956c6b52e21635fa16ccd594c1 325 PRINTS PR00960 LmbP protein signature 241 265 6.5E-35 T 10-11-2016 IPR001174 Galactokinase/homoserine kinase GO:0005524|GO:0008152|GO:0016301 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478 A4G23_RS02270 19161b956c6b52e21635fa16ccd594c1 325 PRINTS PR00960 LmbP protein signature 269 288 6.5E-35 T 10-11-2016 IPR001174 Galactokinase/homoserine kinase GO:0005524|GO:0008152|GO:0016301 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478 A4G23_RS02270 19161b956c6b52e21635fa16ccd594c1 325 Gene3D G3DSA:3.30.230.10 3 169 2.1E-15 T 10-11-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A4G23_RS02270 19161b956c6b52e21635fa16ccd594c1 325 SUPERFAMILY SSF54211 3 171 1.37E-23 T 10-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold A4G23_RS02270 19161b956c6b52e21635fa16ccd594c1 325 Pfam PF08544 GHMP kinases C terminal 226 306 3.4E-6 T 10-11-2016 IPR013750 GHMP kinase, C-terminal domain A4G23_RS02270 19161b956c6b52e21635fa16ccd594c1 325 SUPERFAMILY SSF55060 179 314 2.88E-21 T 10-11-2016 IPR013750 GHMP kinase, C-terminal domain A4G23_RS02270 19161b956c6b52e21635fa16ccd594c1 325 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 94 105 - T 10-11-2016 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 A4G23_RS02270 19161b956c6b52e21635fa16ccd594c1 325 Pfam PF00288 GHMP kinases N terminal domain 88 115 1.7E-5 T 10-11-2016 IPR006204 GHMP kinase N-terminal domain GO:0005524 A4G23_RS02270 19161b956c6b52e21635fa16ccd594c1 325 Gene3D G3DSA:3.30.70.890 225 313 2.9E-11 T 10-11-2016 IPR013750 GHMP kinase, C-terminal domain A4G23_RS02270 19161b956c6b52e21635fa16ccd594c1 325 PIRSF PIRSF036406 1 325 1.4E-74 T 10-11-2016 IPR014606 D,D-heptose 7-phosphate kinase KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478 A4G23_RS03450 ef32c76602ff74bc45064ec17812b3d7 126 SUPERFAMILY SSF55874 23 121 8.51E-18 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS03450 ef32c76602ff74bc45064ec17812b3d7 126 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 27 121 5.4E-11 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS03450 ef32c76602ff74bc45064ec17812b3d7 126 Gene3D G3DSA:3.30.565.10 6 121 1.2E-16 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS03450 ef32c76602ff74bc45064ec17812b3d7 126 SMART SM00387 26 126 1.5E-7 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS07805 8eef33c377097d65c97fc825fd702fcc 360 SUPERFAMILY SSF53807 181 358 2.11E-73 T 10-11-2016 A4G23_RS07805 8eef33c377097d65c97fc825fd702fcc 360 SUPERFAMILY SSF53807 38 127 2.11E-73 T 10-11-2016 A4G23_RS07805 8eef33c377097d65c97fc825fd702fcc 360 Gene3D G3DSA:3.40.50.1980 25 136 2.2E-42 T 10-11-2016 A4G23_RS07805 8eef33c377097d65c97fc825fd702fcc 360 Gene3D G3DSA:3.40.50.1980 181 239 2.2E-42 T 10-11-2016 A4G23_RS07805 8eef33c377097d65c97fc825fd702fcc 360 Pfam PF01297 Zinc-uptake complex component A periplasmic 43 356 2.1E-73 T 10-11-2016 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 A4G23_RS07805 8eef33c377097d65c97fc825fd702fcc 360 Gene3D G3DSA:3.40.50.1980 240 358 4.5E-35 T 10-11-2016 A4G23_RS25920 47e0937120afb519be7746c4d3a5ae16 293 SUPERFAMILY SSF50022 172 278 1.57E-26 T 10-11-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A4G23_RS25920 47e0937120afb519be7746c4d3a5ae16 293 Pfam PF00355 Rieske [2Fe-2S] domain 179 265 1.6E-17 T 10-11-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A4G23_RS25920 47e0937120afb519be7746c4d3a5ae16 293 Gene3D G3DSA:2.102.10.10 175 280 7.6E-28 T 10-11-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A4G23_RS25920 47e0937120afb519be7746c4d3a5ae16 293 Pfam PF09990 Predicted membrane protein (DUF2231) 78 160 6.4E-5 T 10-11-2016 IPR019251 Domain of unknown function DUF2231, transmembrane A4G23_RS04905 f2d30c63f5f6d8ce97841f4088328cd9 371 SUPERFAMILY SSF51735 137 303 2.15E-47 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS04905 f2d30c63f5f6d8ce97841f4088328cd9 371 ProSitePatterns PS00836 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 1. 4 30 - T 10-11-2016 IPR008142 Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 GO:0016491|GO:0055114 Reactome: R-HSA-71403 A4G23_RS04905 f2d30c63f5f6d8ce97841f4088328cd9 371 SMART SM01003 4 137 4.3E-82 T 10-11-2016 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal A4G23_RS04905 f2d30c63f5f6d8ce97841f4088328cd9 371 Gene3D G3DSA:3.50.50.60 178 194 2.8E-5 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS04905 f2d30c63f5f6d8ce97841f4088328cd9 371 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 368 3.6E-174 T 10-11-2016 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 A4G23_RS04905 f2d30c63f5f6d8ce97841f4088328cd9 371 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 137 3.9E-48 T 10-11-2016 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal A4G23_RS04905 f2d30c63f5f6d8ce97841f4088328cd9 371 SUPERFAMILY SSF52283 305 360 1.53E-69 T 10-11-2016 A4G23_RS04905 f2d30c63f5f6d8ce97841f4088328cd9 371 SUPERFAMILY SSF52283 1 137 1.53E-69 T 10-11-2016 A4G23_RS04905 f2d30c63f5f6d8ce97841f4088328cd9 371 PIRSF PIRSF000183 1 371 3.1E-167 T 10-11-2016 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 A4G23_RS04905 f2d30c63f5f6d8ce97841f4088328cd9 371 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 141 352 3.8E-80 T 10-11-2016 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain A4G23_RS04905 f2d30c63f5f6d8ce97841f4088328cd9 371 Gene3D G3DSA:3.40.50.1770 195 357 1.2E-27 T 10-11-2016 A4G23_RS04905 f2d30c63f5f6d8ce97841f4088328cd9 371 SMART SM01002 149 297 1.7E-80 T 10-11-2016 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain A4G23_RS04905 f2d30c63f5f6d8ce97841f4088328cd9 371 Gene3D G3DSA:3.40.50.1770 1 177 1.2E-58 T 10-11-2016 A4G23_RS23140 988e130a6486e1c5b796b24f3d4a1688 442 Pfam PF04055 Radical SAM superfamily 43 221 3.7E-13 T 10-11-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 A4G23_RS23140 988e130a6486e1c5b796b24f3d4a1688 442 SUPERFAMILY SSF102114 4 428 2.88E-71 T 10-11-2016 A4G23_RS23140 988e130a6486e1c5b796b24f3d4a1688 442 SMART SM00729 37 263 4.8E-34 T 10-11-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 A4G23_RS23140 988e130a6486e1c5b796b24f3d4a1688 442 Gene3D G3DSA:3.80.30.20 38 264 6.7E-24 T 10-11-2016 IPR023404 Radical SAM, alpha/beta horseshoe A4G23_RS02825 ce7bdb275705ebfe577a3d859d9afe6a 391 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 2 245 9.9E-55 T 10-11-2016 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 A4G23_RS02825 ce7bdb275705ebfe577a3d859d9afe6a 391 Pfam PF12320 Type 5 capsule protein repressor C-terminal domain 268 356 2.5E-7 T 10-11-2016 IPR026843 Nuclease SbcCD subunit D, C-terminal domain A4G23_RS02825 ce7bdb275705ebfe577a3d859d9afe6a 391 Gene3D G3DSA:3.60.21.10 2 266 7.4E-73 T 10-11-2016 IPR029052 Metallo-dependent phosphatase-like A4G23_RS02825 ce7bdb275705ebfe577a3d859d9afe6a 391 Pfam PF00149 Calcineurin-like phosphoesterase 2 218 4.8E-13 T 10-11-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 A4G23_RS02825 ce7bdb275705ebfe577a3d859d9afe6a 391 SUPERFAMILY SSF56300 2 305 1.46E-54 T 10-11-2016 IPR029052 Metallo-dependent phosphatase-like A4G23_RS02305 e4bcd53c77699b798932c020e52e6a53 476 Gene3D G3DSA:3.30.470.20 157 353 6.4E-13 T 10-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 A4G23_RS02305 e4bcd53c77699b798932c020e52e6a53 476 Pfam PF02222 ATP-grasp domain 206 347 9.2E-8 T 10-11-2016 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type A4G23_RS02305 e4bcd53c77699b798932c020e52e6a53 476 SUPERFAMILY SSF56059 165 356 2.47E-22 T 10-11-2016 A4G23_RS09805 a90708847995a30f8b5dbb27c5d6b48a 220 Pfam PF13419 Haloacid dehalogenase-like hydrolase 9 185 8.4E-9 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS09805 a90708847995a30f8b5dbb27c5d6b48a 220 Gene3D G3DSA:3.40.50.1000 76 213 3.3E-17 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS09805 a90708847995a30f8b5dbb27c5d6b48a 220 SUPERFAMILY SSF56784 6 213 5.02E-32 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS18630 4c589c5dbf2d3af6488a8155bccd9e94 202 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 6 194 3.4E-42 T 10-11-2016 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 A4G23_RS18630 4c589c5dbf2d3af6488a8155bccd9e94 202 Pfam PF01914 MarC family integral membrane protein 6 197 1.3E-45 T 10-11-2016 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 A4G23_RS14095 b18f5602c1ec1a1b491d43bf26a53f2c 188 SUPERFAMILY SSF48317 38 185 3.76E-6 T 10-11-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A4G23_RS08185 a373ba36b6e795cf0f5e986e78397637 323 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 249 1.9E-52 T 10-11-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 A4G23_RS08185 a373ba36b6e795cf0f5e986e78397637 323 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 4 321 2.7E-97 T 10-11-2016 IPR005886 UDP-glucose 4-epimerase GalE GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 A4G23_RS08185 a373ba36b6e795cf0f5e986e78397637 323 Gene3D G3DSA:3.40.50.720 1 169 6.3E-47 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS08185 a373ba36b6e795cf0f5e986e78397637 323 SUPERFAMILY SSF51735 1 315 7.2E-83 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS08185 a373ba36b6e795cf0f5e986e78397637 323 Gene3D G3DSA:3.90.25.10 251 322 1.2E-36 T 10-11-2016 A4G23_RS08185 a373ba36b6e795cf0f5e986e78397637 323 Gene3D G3DSA:3.90.25.10 170 218 1.2E-36 T 10-11-2016 A4G23_RS00130 b003190c82f5b762b3ff9febdf249a0e 246 SUPERFAMILY SSF53448 5 225 5.06E-36 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS00130 b003190c82f5b762b3ff9febdf249a0e 246 Pfam PF00535 Glycosyl transferase family 2 6 145 8.3E-23 T 10-11-2016 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A4G23_RS00130 b003190c82f5b762b3ff9febdf249a0e 246 Gene3D G3DSA:3.90.550.10 6 217 8.0E-29 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS27310 b003190c82f5b762b3ff9febdf249a0e 246 SUPERFAMILY SSF53448 5 225 5.06E-36 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS27310 b003190c82f5b762b3ff9febdf249a0e 246 Pfam PF00535 Glycosyl transferase family 2 6 145 8.3E-23 T 10-11-2016 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A4G23_RS27310 b003190c82f5b762b3ff9febdf249a0e 246 Gene3D G3DSA:3.90.550.10 6 217 8.0E-29 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS13465 306b2c5bddb47b01c20c70d0824b9a6f 376 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 374 2.4E-90 T 10-11-2016 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4G23_RS13465 306b2c5bddb47b01c20c70d0824b9a6f 376 SUPERFAMILY SSF55979 2 119 2.9E-24 T 10-11-2016 A4G23_RS13465 306b2c5bddb47b01c20c70d0824b9a6f 376 PIRSF PIRSF000804 1 375 4.4E-94 T 10-11-2016 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4G23_RS13465 306b2c5bddb47b01c20c70d0824b9a6f 376 Gene3D G3DSA:3.10.150.10 126 250 8.4E-29 T 10-11-2016 A4G23_RS13465 306b2c5bddb47b01c20c70d0824b9a6f 376 Gene3D G3DSA:3.10.150.10 2 120 4.2E-32 T 10-11-2016 A4G23_RS13465 306b2c5bddb47b01c20c70d0824b9a6f 376 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 2 118 4.8E-39 T 10-11-2016 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4G23_RS13465 306b2c5bddb47b01c20c70d0824b9a6f 376 SUPERFAMILY SSF55979 249 374 5.23E-29 T 10-11-2016 A4G23_RS13465 306b2c5bddb47b01c20c70d0824b9a6f 376 SMART SM00480 17 370 2.0E-144 T 10-11-2016 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4G23_RS13465 306b2c5bddb47b01c20c70d0824b9a6f 376 SUPERFAMILY SSF55979 126 249 5.97E-18 T 10-11-2016 A4G23_RS13465 306b2c5bddb47b01c20c70d0824b9a6f 376 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 248 372 2.2E-36 T 10-11-2016 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4G23_RS13465 306b2c5bddb47b01c20c70d0824b9a6f 376 Pfam PF02767 DNA polymerase III beta subunit, central domain 127 246 7.2E-32 T 10-11-2016 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4G23_RS13465 306b2c5bddb47b01c20c70d0824b9a6f 376 Gene3D G3DSA:3.10.150.10 252 374 2.1E-38 T 10-11-2016 A4G23_RS11630 429a2eca040072ce41057ef24138836d 338 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 1 111 7.8E-27 T 10-11-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 A4G23_RS11630 429a2eca040072ce41057ef24138836d 338 Gene3D G3DSA:3.30.360.10 137 312 2.3E-60 T 10-11-2016 A4G23_RS11630 429a2eca040072ce41057ef24138836d 338 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 1 329 1.3E-111 T 10-11-2016 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A4G23_RS11630 429a2eca040072ce41057ef24138836d 338 Gene3D G3DSA:3.40.50.720 1 136 1.7E-46 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS11630 429a2eca040072ce41057ef24138836d 338 SMART SM00859 1 113 4.3E-27 T 10-11-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 A4G23_RS11630 429a2eca040072ce41057ef24138836d 338 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 133 314 4.2E-42 T 10-11-2016 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A4G23_RS11630 429a2eca040072ce41057ef24138836d 338 SUPERFAMILY SSF55347 123 316 5.12E-59 T 10-11-2016 A4G23_RS11630 429a2eca040072ce41057ef24138836d 338 PIRSF PIRSF000148 1 334 1.1E-107 T 10-11-2016 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A4G23_RS11630 429a2eca040072ce41057ef24138836d 338 SUPERFAMILY SSF51735 1 151 9.24E-41 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS17370 61afd29020553b360832c99fa59007dc 584 SUPERFAMILY SSF56425 236 354 2.54E-42 T 10-11-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4G23_RS17370 61afd29020553b360832c99fa59007dc 584 SUPERFAMILY SSF51905 358 438 6.87E-72 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS17370 61afd29020553b360832c99fa59007dc 584 SUPERFAMILY SSF51905 2 259 6.87E-72 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS17370 61afd29020553b360832c99fa59007dc 584 SUPERFAMILY SSF46977 446 584 5.1E-52 T 10-11-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4G23_RS17370 61afd29020553b360832c99fa59007dc 584 Gene3D G3DSA:1.20.58.100 426 542 3.7E-43 T 10-11-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4G23_RS17370 61afd29020553b360832c99fa59007dc 584 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 378 385 2.4E-5 T 10-11-2016 A4G23_RS17370 61afd29020553b360832c99fa59007dc 584 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 2.4E-5 T 10-11-2016 A4G23_RS17370 61afd29020553b360832c99fa59007dc 584 Pfam PF00890 FAD binding domain 7 400 3.3E-112 T 10-11-2016 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4G23_RS17370 61afd29020553b360832c99fa59007dc 584 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 40 49 - T 10-11-2016 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4G23_RS17370 61afd29020553b360832c99fa59007dc 584 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 4 584 1.7E-278 T 10-11-2016 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4G23_RS17370 61afd29020553b360832c99fa59007dc 584 Pfam PF02910 Fumarate reductase flavoprotein C-term 454 584 7.5E-46 T 10-11-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4G23_RS17370 61afd29020553b360832c99fa59007dc 584 Gene3D G3DSA:4.10.80.40 543 580 5.7E-18 T 10-11-2016 A4G23_RS17370 61afd29020553b360832c99fa59007dc 584 Gene3D G3DSA:3.50.50.60 350 421 1.7E-113 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS17370 61afd29020553b360832c99fa59007dc 584 Gene3D G3DSA:3.50.50.60 2 242 1.7E-113 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS17370 61afd29020553b360832c99fa59007dc 584 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 7 584 2.0E-247 T 10-11-2016 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4G23_RS17370 61afd29020553b360832c99fa59007dc 584 PIRSF PIRSF000171 1 578 3.7E-49 T 10-11-2016 IPR030664 Succinate dehydrogenase/fumarate reductase, alpha/adenylylsulphate reductase subunit Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4G23_RS17370 61afd29020553b360832c99fa59007dc 584 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 1.2E-5 T 10-11-2016 A4G23_RS17370 61afd29020553b360832c99fa59007dc 584 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 363 385 1.2E-5 T 10-11-2016 A4G23_RS17370 61afd29020553b360832c99fa59007dc 584 Gene3D G3DSA:3.90.700.10 243 349 6.0E-41 T 10-11-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4G23_RS10775 fbfbfc61e6298a2d44c35153e4d1834f 393 Gene3D G3DSA:1.25.40.10 193 270 5.0E-4 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS10775 fbfbfc61e6298a2d44c35153e4d1834f 393 Gene3D G3DSA:1.25.40.10 320 389 5.0E-4 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS10775 fbfbfc61e6298a2d44c35153e4d1834f 393 Gene3D G3DSA:1.10.260.40 5 77 3.2E-17 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS10775 fbfbfc61e6298a2d44c35153e4d1834f 393 SMART SM00530 8 64 5.4E-13 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS10775 fbfbfc61e6298a2d44c35153e4d1834f 393 SUPERFAMILY SSF48452 153 263 1.2E-5 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS10775 fbfbfc61e6298a2d44c35153e4d1834f 393 Pfam PF13560 Helix-turn-helix domain 4 61 7.7E-14 T 10-11-2016 A4G23_RS10775 fbfbfc61e6298a2d44c35153e4d1834f 393 SUPERFAMILY SSF47413 3 68 4.83E-16 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS15995 72bfcd4df4fa3536c8aa1dd71af209cd 606 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 133 145 - T 10-11-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 A4G23_RS15995 72bfcd4df4fa3536c8aa1dd71af209cd 606 Gene3D G3DSA:1.10.510.10 98 265 4.6E-37 T 10-11-2016 A4G23_RS15995 72bfcd4df4fa3536c8aa1dd71af209cd 606 SUPERFAMILY SSF56112 11 265 3.91E-62 T 10-11-2016 IPR011009 Protein kinase-like domain A4G23_RS15995 72bfcd4df4fa3536c8aa1dd71af209cd 606 SMART SM00220 15 267 1.6E-42 T 10-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4G23_RS15995 72bfcd4df4fa3536c8aa1dd71af209cd 606 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 21 43 - T 10-11-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 A4G23_RS15995 72bfcd4df4fa3536c8aa1dd71af209cd 606 Pfam PF00069 Protein kinase domain 15 262 7.5E-36 T 10-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4G23_RS15995 72bfcd4df4fa3536c8aa1dd71af209cd 606 Gene3D G3DSA:3.30.200.20 8 82 4.2E-15 T 10-11-2016 A4G23_RS04510 9daf5479c33e368a30edc0f6f5ff6ed7 136 PIRSF PIRSF021320 2 136 2.2E-41 T 10-11-2016 IPR009326 Protein of unknown function DUF984 A4G23_RS04510 9daf5479c33e368a30edc0f6f5ff6ed7 136 Gene3D G3DSA:3.10.400.10 6 136 1.5E-45 T 10-11-2016 A4G23_RS04510 9daf5479c33e368a30edc0f6f5ff6ed7 136 Pfam PF04266 ASCH domain 19 134 1.5E-17 T 10-11-2016 IPR007374 ASCH domain A4G23_RS04510 9daf5479c33e368a30edc0f6f5ff6ed7 136 SMART SM01022 12 135 4.4E-29 T 10-11-2016 IPR007374 ASCH domain A4G23_RS04510 9daf5479c33e368a30edc0f6f5ff6ed7 136 SUPERFAMILY SSF88697 15 136 1.24E-32 T 10-11-2016 IPR015947 PUA-like domain A4G23_RS18415 6e158bc8f52556582a0e6999bf43f830 600 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 121 510 3.8E-63 T 10-11-2016 IPR000914 Solute-binding protein family 5 domain A4G23_RS18415 6e158bc8f52556582a0e6999bf43f830 600 Gene3D G3DSA:3.10.105.10 368 567 3.1E-40 T 10-11-2016 A4G23_RS18415 6e158bc8f52556582a0e6999bf43f830 600 Gene3D G3DSA:3.90.76.10 86 253 3.6E-21 T 10-11-2016 A4G23_RS18415 6e158bc8f52556582a0e6999bf43f830 600 SUPERFAMILY SSF53850 74 597 6.21E-81 T 10-11-2016 A4G23_RS18415 6e158bc8f52556582a0e6999bf43f830 600 Gene3D G3DSA:3.40.190.10 254 367 2.0E-14 T 10-11-2016 A4G23_RS18415 6e158bc8f52556582a0e6999bf43f830 600 PIRSF PIRSF002741 46 600 1.3E-55 T 10-11-2016 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A4G23_RS08380 7c2ef53d8c3799ae353e916143418fa9 211 SUPERFAMILY SSF54719 97 204 5.24E-38 T 10-11-2016 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 A4G23_RS08380 7c2ef53d8c3799ae353e916143418fa9 211 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 97 198 1.0E-32 T 10-11-2016 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 A4G23_RS08380 7c2ef53d8c3799ae353e916143418fa9 211 SUPERFAMILY SSF46609 3 89 3.27E-30 T 10-11-2016 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 A4G23_RS08380 7c2ef53d8c3799ae353e916143418fa9 211 Gene3D G3DSA:1.10.287.990 22 84 5.6E-22 T 10-11-2016 A4G23_RS08380 7c2ef53d8c3799ae353e916143418fa9 211 PRINTS PR01703 Manganese superoxide dismutase signature 7 18 7.5E-19 T 10-11-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 A4G23_RS08380 7c2ef53d8c3799ae353e916143418fa9 211 PRINTS PR01703 Manganese superoxide dismutase signature 125 133 7.5E-19 T 10-11-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 A4G23_RS08380 7c2ef53d8c3799ae353e916143418fa9 211 PRINTS PR01703 Manganese superoxide dismutase signature 28 41 7.5E-19 T 10-11-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 A4G23_RS08380 7c2ef53d8c3799ae353e916143418fa9 211 PRINTS PR01703 Manganese superoxide dismutase signature 67 80 7.5E-19 T 10-11-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 A4G23_RS08380 7c2ef53d8c3799ae353e916143418fa9 211 PRINTS PR01703 Manganese superoxide dismutase signature 163 175 7.5E-19 T 10-11-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 A4G23_RS08380 7c2ef53d8c3799ae353e916143418fa9 211 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 165 172 - T 10-11-2016 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 A4G23_RS08380 7c2ef53d8c3799ae353e916143418fa9 211 PIRSF PIRSF000349 1 207 1.2E-71 T 10-11-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 A4G23_RS08380 7c2ef53d8c3799ae353e916143418fa9 211 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 4 83 3.5E-30 T 10-11-2016 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 A4G23_RS13835 c341014d66602b0e4ce1727f6dd934fe 477 SMART SM00331 279 476 6.5E-15 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS13835 c341014d66602b0e4ce1727f6dd934fe 477 SUPERFAMILY SSF55781 177 259 4.66E-5 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS13835 c341014d66602b0e4ce1727f6dd934fe 477 Gene3D G3DSA:3.30.450.40 41 97 4.1E-4 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS13835 c341014d66602b0e4ce1727f6dd934fe 477 Gene3D G3DSA:3.30.450.40 147 258 4.1E-4 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS13835 c341014d66602b0e4ce1727f6dd934fe 477 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 305 475 1.3E-32 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS03565 4f3551325a6dc351e19c43cdf3748ce3 331 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 3 147 1.6E-40 T 10-11-2016 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 A4G23_RS03565 4f3551325a6dc351e19c43cdf3748ce3 331 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 1.2E-20 T 10-11-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A4G23_RS03565 4f3551325a6dc351e19c43cdf3748ce3 331 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 275 298 1.2E-20 T 10-11-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A4G23_RS03565 4f3551325a6dc351e19c43cdf3748ce3 331 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 49 68 1.2E-20 T 10-11-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A4G23_RS03565 4f3551325a6dc351e19c43cdf3748ce3 331 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 263 272 1.2E-20 T 10-11-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A4G23_RS03565 4f3551325a6dc351e19c43cdf3748ce3 331 PRINTS PR00101 Aspartate carbamoyltransferase signature 77 86 1.2E-30 T 10-11-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 A4G23_RS03565 4f3551325a6dc351e19c43cdf3748ce3 331 PRINTS PR00101 Aspartate carbamoyltransferase signature 226 235 1.2E-30 T 10-11-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 A4G23_RS03565 4f3551325a6dc351e19c43cdf3748ce3 331 PRINTS PR00101 Aspartate carbamoyltransferase signature 134 151 1.2E-30 T 10-11-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 A4G23_RS03565 4f3551325a6dc351e19c43cdf3748ce3 331 PRINTS PR00101 Aspartate carbamoyltransferase signature 39 61 1.2E-30 T 10-11-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 A4G23_RS03565 4f3551325a6dc351e19c43cdf3748ce3 331 PRINTS PR00101 Aspartate carbamoyltransferase signature 291 305 1.2E-30 T 10-11-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 A4G23_RS03565 4f3551325a6dc351e19c43cdf3748ce3 331 PRINTS PR00101 Aspartate carbamoyltransferase signature 267 272 1.2E-30 T 10-11-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 A4G23_RS03565 4f3551325a6dc351e19c43cdf3748ce3 331 Gene3D G3DSA:3.40.50.1370 2 142 7.7E-50 T 10-11-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A4G23_RS03565 4f3551325a6dc351e19c43cdf3748ce3 331 Gene3D G3DSA:3.40.50.1370 143 288 3.3E-48 T 10-11-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A4G23_RS03565 4f3551325a6dc351e19c43cdf3748ce3 331 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 3 310 3.2E-90 T 10-11-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 A4G23_RS03565 4f3551325a6dc351e19c43cdf3748ce3 331 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 2 312 41.26 T 10-11-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 A4G23_RS03565 4f3551325a6dc351e19c43cdf3748ce3 331 SUPERFAMILY SSF53671 2 312 3.27E-94 T 10-11-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A4G23_RS03565 4f3551325a6dc351e19c43cdf3748ce3 331 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 49 56 - T 10-11-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A4G23_RS03565 4f3551325a6dc351e19c43cdf3748ce3 331 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 163 309 3.7E-23 T 10-11-2016 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 A4G23_RS19805 31c2bc8306160ccb9dc57627a62d1713 225 SUPERFAMILY SSF52172 1 162 5.83E-31 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS19805 31c2bc8306160ccb9dc57627a62d1713 225 Pfam PF00072 Response regulator receiver domain 3 114 3.5E-20 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS19805 31c2bc8306160ccb9dc57627a62d1713 225 PIRSF PIRSF006171 1 222 8.8E-70 T 10-11-2016 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0001071|GO:0003677|GO:0005737|GO:0009605 A4G23_RS19805 31c2bc8306160ccb9dc57627a62d1713 225 Gene3D G3DSA:3.40.50.2300 1 119 2.6E-26 T 10-11-2016 A4G23_RS19805 31c2bc8306160ccb9dc57627a62d1713 225 Gene3D G3DSA:1.10.10.10 163 207 4.1E-5 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS19805 31c2bc8306160ccb9dc57627a62d1713 225 SMART SM00448 1 114 2.4E-23 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS09455 61fb43878364c35da8ca18453c5a0264 92 Pfam PF02597 ThiS family 5 90 5.2E-19 T 10-11-2016 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 A4G23_RS09455 61fb43878364c35da8ca18453c5a0264 92 Gene3D G3DSA:3.10.20.30 3 88 6.6E-31 T 10-11-2016 IPR012675 Beta-grasp domain A4G23_RS09455 61fb43878364c35da8ca18453c5a0264 92 SUPERFAMILY SSF54285 1 90 1.74E-24 T 10-11-2016 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp A4G23_RS00150 7b8426bbe68f2690cd23b71fc11c7338 276 Gene3D G3DSA:3.20.20.80 47 267 3.1E-43 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS00150 7b8426bbe68f2690cd23b71fc11c7338 276 SUPERFAMILY SSF51445 47 269 2.0E-40 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS00150 7b8426bbe68f2690cd23b71fc11c7338 276 Pfam PF08924 Domain of unknown function (DUF1906) 60 195 6.2E-37 T 10-11-2016 IPR015020 Protein of unknown function DUF1906 A4G23_RS01415 57505cde2f50c339dea73a5d21cbdde6 399 PRINTS PR00723 Subtilisin serine protease family (S8) signature 342 358 1.6E-19 T 10-11-2016 IPR015500 Peptidase S8, subtilisin-related A4G23_RS01415 57505cde2f50c339dea73a5d21cbdde6 399 PRINTS PR00723 Subtilisin serine protease family (S8) signature 152 171 1.6E-19 T 10-11-2016 IPR015500 Peptidase S8, subtilisin-related A4G23_RS01415 57505cde2f50c339dea73a5d21cbdde6 399 PRINTS PR00723 Subtilisin serine protease family (S8) signature 190 203 1.6E-19 T 10-11-2016 IPR015500 Peptidase S8, subtilisin-related A4G23_RS01415 57505cde2f50c339dea73a5d21cbdde6 399 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 194 204 - T 10-11-2016 IPR022398 Peptidase S8, subtilisin, His-active site A4G23_RS01415 57505cde2f50c339dea73a5d21cbdde6 399 SUPERFAMILY SSF54897 48 111 1.76E-10 T 10-11-2016 IPR009020 Proteinase propeptide inhibitor A4G23_RS01415 57505cde2f50c339dea73a5d21cbdde6 399 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 157 168 - T 10-11-2016 IPR023827 Peptidase S8, subtilisin, Asp-active site A4G23_RS01415 57505cde2f50c339dea73a5d21cbdde6 399 Pfam PF05922 Peptidase inhibitor I9 71 111 2.9E-10 T 10-11-2016 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 A4G23_RS01415 57505cde2f50c339dea73a5d21cbdde6 399 Gene3D G3DSA:3.40.50.200 128 380 1.3E-77 T 10-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4G23_RS01415 57505cde2f50c339dea73a5d21cbdde6 399 Gene3D G3DSA:3.30.70.80 47 113 2.3E-14 T 10-11-2016 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 A4G23_RS01415 57505cde2f50c339dea73a5d21cbdde6 399 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 343 353 - T 10-11-2016 IPR023828 Peptidase S8, subtilisin, Ser-active site A4G23_RS01415 57505cde2f50c339dea73a5d21cbdde6 399 Pfam PF00082 Subtilase family 159 376 9.1E-33 T 10-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4G23_RS01415 57505cde2f50c339dea73a5d21cbdde6 399 SUPERFAMILY SSF52743 128 380 1.03E-71 T 10-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4G23_RS07015 dfdb569e2cb5747f0ce4e38810f62ab8 230 Pfam PF16859 Bacterial transcriptional repressor C-terminal 111 223 1.9E-29 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS07015 dfdb569e2cb5747f0ce4e38810f62ab8 230 Gene3D G3DSA:1.10.357.10 64 230 2.8E-46 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS07015 dfdb569e2cb5747f0ce4e38810f62ab8 230 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 69 1.8E-13 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS07015 dfdb569e2cb5747f0ce4e38810f62ab8 230 SUPERFAMILY SSF46689 16 79 2.94E-16 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS07015 dfdb569e2cb5747f0ce4e38810f62ab8 230 Gene3D G3DSA:1.10.10.60 16 63 2.9E-22 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS07015 dfdb569e2cb5747f0ce4e38810f62ab8 230 SUPERFAMILY SSF48498 112 230 2.11E-25 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS07015 dfdb569e2cb5747f0ce4e38810f62ab8 230 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 2.2E-7 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS07015 dfdb569e2cb5747f0ce4e38810f62ab8 230 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 2.2E-7 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS19755 0e9c7d7bc8d5070003bb74227d090b68 316 SUPERFAMILY SSF52833 42 148 1.49E-29 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS19755 0e9c7d7bc8d5070003bb74227d090b68 316 Pfam PF00085 Thioredoxin 43 145 1.4E-22 T 10-11-2016 IPR013766 Thioredoxin domain GO:0045454 A4G23_RS19755 0e9c7d7bc8d5070003bb74227d090b68 316 Gene3D G3DSA:1.25.40.10 233 316 1.3E-12 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS19755 0e9c7d7bc8d5070003bb74227d090b68 316 Gene3D G3DSA:1.25.40.10 179 223 7.8E-4 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS19755 0e9c7d7bc8d5070003bb74227d090b68 316 Gene3D G3DSA:3.40.30.10 39 147 5.0E-28 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS19755 0e9c7d7bc8d5070003bb74227d090b68 316 Pfam PF14561 Tetratricopeptide repeat 231 316 4.7E-23 T 10-11-2016 A4G23_RS18360 4ba82a8b06496419488378704aa43651 369 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 71 359 1.9E-68 T 10-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4G23_RS18360 4ba82a8b06496419488378704aa43651 369 Gene3D G3DSA:3.40.50.1100 136 364 1.0E-54 T 10-11-2016 A4G23_RS18360 4ba82a8b06496419488378704aa43651 369 SUPERFAMILY SSF53686 5 364 3.8E-84 T 10-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4G23_RS18360 4ba82a8b06496419488378704aa43651 369 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 92 105 - T 10-11-2016 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 A4G23_RS00180 d7aabf989ff047a0ac3530a7054a2186 757 SMART SM00637 655 755 2.1E-43 T 10-11-2016 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 A4G23_RS00180 d7aabf989ff047a0ac3530a7054a2186 757 SUPERFAMILY SSF49265 556 650 6.65E-18 T 10-11-2016 IPR003961 Fibronectin type III GO:0005515 A4G23_RS00180 d7aabf989ff047a0ac3530a7054a2186 757 Gene3D G3DSA:2.60.40.10 557 646 1.3E-22 T 10-11-2016 IPR013783 Immunoglobulin-like fold A4G23_RS00180 d7aabf989ff047a0ac3530a7054a2186 757 Gene3D G3DSA:2.60.40.1180 460 546 1.1E-4 T 10-11-2016 IPR013780 Glycosyl hydrolase, all-beta A4G23_RS00180 d7aabf989ff047a0ac3530a7054a2186 757 Pfam PF00553 Cellulose binding domain 655 755 8.7E-32 T 10-11-2016 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 A4G23_RS00180 d7aabf989ff047a0ac3530a7054a2186 757 Pfam PF00041 Fibronectin type III domain 561 639 4.1E-9 T 10-11-2016 IPR003961 Fibronectin type III GO:0005515 A4G23_RS00180 d7aabf989ff047a0ac3530a7054a2186 757 Gene3D G3DSA:2.60.40.290 654 755 9.1E-37 T 10-11-2016 IPR012291 Cellulose-binding family II/chitobiase, carbohydrate-binding domain GO:0004553|GO:0030247 A4G23_RS00180 d7aabf989ff047a0ac3530a7054a2186 757 SUPERFAMILY SSF49384 652 755 2.58E-31 T 10-11-2016 IPR008965 Carbohydrate-binding domain GO:0030246 A4G23_RS00180 d7aabf989ff047a0ac3530a7054a2186 757 Gene3D G3DSA:3.20.20.80 191 399 4.6E-4 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS00180 d7aabf989ff047a0ac3530a7054a2186 757 SMART SM00060 559 636 1.0E-10 T 10-11-2016 IPR003961 Fibronectin type III GO:0005515 A4G23_RS00180 d7aabf989ff047a0ac3530a7054a2186 757 Pfam PF12891 Glycoside hydrolase family 44 85 332 1.8E-80 T 10-11-2016 IPR024745 Glycoside hydrolase, family 44 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 A4G23_RS00180 d7aabf989ff047a0ac3530a7054a2186 757 SUPERFAMILY SSF51445 178 270 3.07E-27 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS00180 d7aabf989ff047a0ac3530a7054a2186 757 SUPERFAMILY SSF51445 303 428 3.07E-27 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS00180 d7aabf989ff047a0ac3530a7054a2186 757 SUPERFAMILY SSF51445 41 136 3.07E-27 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS04140 10b9b252035ff3e2d1176e503f6b76f3 395 Pfam PF00082 Subtilase family 58 321 9.9E-46 T 10-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4G23_RS04140 10b9b252035ff3e2d1176e503f6b76f3 395 PRINTS PR00723 Subtilisin serine protease family (S8) signature 270 286 1.4E-15 T 10-11-2016 IPR015500 Peptidase S8, subtilisin-related A4G23_RS04140 10b9b252035ff3e2d1176e503f6b76f3 395 PRINTS PR00723 Subtilisin serine protease family (S8) signature 58 77 1.4E-15 T 10-11-2016 IPR015500 Peptidase S8, subtilisin-related A4G23_RS04140 10b9b252035ff3e2d1176e503f6b76f3 395 PRINTS PR00723 Subtilisin serine protease family (S8) signature 98 111 1.4E-15 T 10-11-2016 IPR015500 Peptidase S8, subtilisin-related A4G23_RS04140 10b9b252035ff3e2d1176e503f6b76f3 395 SUPERFAMILY SSF52743 40 331 4.19E-82 T 10-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4G23_RS04140 10b9b252035ff3e2d1176e503f6b76f3 395 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 63 74 - T 10-11-2016 IPR023827 Peptidase S8, subtilisin, Asp-active site A4G23_RS04140 10b9b252035ff3e2d1176e503f6b76f3 395 TIGRFAM TIGR03921 T7SS_mycosin: type VII secretion-associated serine protease mycosin 48 389 2.2E-100 T 10-11-2016 IPR023834 Type VII secretion system peptidase S8A, mycosin-1 A4G23_RS04140 10b9b252035ff3e2d1176e503f6b76f3 395 Gene3D G3DSA:3.40.50.200 37 332 5.5E-81 T 10-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4G23_RS05695 1382ce3e57e8b9f1e09c106b1b6900bd 318 Gene3D G3DSA:3.40.50.300 32 189 5.5E-21 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05695 1382ce3e57e8b9f1e09c106b1b6900bd 318 PIRSF PIRSF005052 35 318 1.7E-110 T 10-11-2016 IPR005337 RapZ-like family GO:0005524 A4G23_RS05695 1382ce3e57e8b9f1e09c106b1b6900bd 318 Pfam PF03668 P-loop ATPase protein family 36 318 7.7E-110 T 10-11-2016 IPR005337 RapZ-like family GO:0005524 A4G23_RS05695 1382ce3e57e8b9f1e09c106b1b6900bd 318 SUPERFAMILY SSF52540 36 187 4.17E-14 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05695 1382ce3e57e8b9f1e09c106b1b6900bd 318 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 35 317 40.946 T 10-11-2016 IPR005337 RapZ-like family GO:0005524 A4G23_RS02180 d41917739e7569f2acd131baa55db34a 739 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 24 351 1.0E-66 T 10-11-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4G23_RS02180 d41917739e7569f2acd131baa55db34a 739 Gene3D G3DSA:3.40.50.1700 377 603 3.9E-49 T 10-11-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 A4G23_RS02180 d41917739e7569f2acd131baa55db34a 739 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 391 600 1.4E-39 T 10-11-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 A4G23_RS02180 d41917739e7569f2acd131baa55db34a 739 SMART SM01217 636 705 5.2E-27 T 10-11-2016 IPR026891 Fibronectin type III-like domain A4G23_RS02180 d41917739e7569f2acd131baa55db34a 739 SUPERFAMILY SSF51445 3 390 5.69E-91 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS02180 d41917739e7569f2acd131baa55db34a 739 Pfam PF14310 Fibronectin type III-like domain 636 705 2.3E-19 T 10-11-2016 IPR026891 Fibronectin type III-like domain A4G23_RS02180 d41917739e7569f2acd131baa55db34a 739 PRINTS PR00133 Glycosyl hydrolase family 3 signature 272 290 7.2E-20 T 10-11-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4G23_RS02180 d41917739e7569f2acd131baa55db34a 739 PRINTS PR00133 Glycosyl hydrolase family 3 signature 170 186 7.2E-20 T 10-11-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4G23_RS02180 d41917739e7569f2acd131baa55db34a 739 PRINTS PR00133 Glycosyl hydrolase family 3 signature 101 117 7.2E-20 T 10-11-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4G23_RS02180 d41917739e7569f2acd131baa55db34a 739 PRINTS PR00133 Glycosyl hydrolase family 3 signature 201 217 7.2E-20 T 10-11-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4G23_RS02180 d41917739e7569f2acd131baa55db34a 739 PRINTS PR00133 Glycosyl hydrolase family 3 signature 124 143 7.2E-20 T 10-11-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4G23_RS02180 d41917739e7569f2acd131baa55db34a 739 SUPERFAMILY SSF52279 392 603 4.71E-40 T 10-11-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 A4G23_RS02180 d41917739e7569f2acd131baa55db34a 739 Gene3D G3DSA:3.20.20.300 4 364 7.5E-95 T 10-11-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4G23_RS14160 3e7d79adb771532878a905d89f85861d 283 Gene3D G3DSA:1.10.600.10 55 277 6.8E-69 T 10-11-2016 IPR008949 Isoprenoid synthase domain A4G23_RS14160 3e7d79adb771532878a905d89f85861d 283 Pfam PF00348 Polyprenyl synthetase 56 277 2.3E-51 T 10-11-2016 IPR000092 Polyprenyl synthetase GO:0008299 A4G23_RS14160 3e7d79adb771532878a905d89f85861d 283 SUPERFAMILY SSF48576 56 276 1.25E-66 T 10-11-2016 IPR008949 Isoprenoid synthase domain A4G23_RS18835 e9a0ec9e70f581f26768c6ed3d5a57e7 510 SUPERFAMILY SSF55486 77 432 1.61E-116 T 10-11-2016 A4G23_RS18835 e9a0ec9e70f581f26768c6ed3d5a57e7 510 Pfam PF10103 Zinicin-like metallopeptidase 78 430 1.2E-126 T 10-11-2016 IPR018766 Zinicin-like metallopeptidase type 2 A4G23_RS18835 e9a0ec9e70f581f26768c6ed3d5a57e7 510 TIGRFAM TIGR03624 TIGR03624: putative hydrolase 78 432 2.6E-123 T 10-11-2016 IPR018766 Zinicin-like metallopeptidase type 2 A4G23_RS02415 2c0d7812da1fa72e069afd5620ae190e 837 Pfam PF00271 Helicase conserved C-terminal domain 284 363 9.3E-6 T 10-11-2016 IPR001650 Helicase, C-terminal A4G23_RS02415 2c0d7812da1fa72e069afd5620ae190e 837 Pfam PF00270 DEAD/DEAH box helicase 33 179 8.1E-10 T 10-11-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A4G23_RS02415 2c0d7812da1fa72e069afd5620ae190e 837 Gene3D G3DSA:3.40.50.300 18 193 5.5E-29 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS02415 2c0d7812da1fa72e069afd5620ae190e 837 SUPERFAMILY SSF52540 44 250 1.15E-40 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS02415 2c0d7812da1fa72e069afd5620ae190e 837 SUPERFAMILY SSF52540 283 375 1.15E-40 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS02415 2c0d7812da1fa72e069afd5620ae190e 837 SMART SM00487 27 212 2.4E-15 T 10-11-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4G23_RS02415 2c0d7812da1fa72e069afd5620ae190e 837 SMART SM00490 277 363 1.2E-12 T 10-11-2016 IPR001650 Helicase, C-terminal A4G23_RS02415 2c0d7812da1fa72e069afd5620ae190e 837 Pfam PF12029 Domain of unknown function (DUF3516) 374 834 1.5E-218 T 10-11-2016 IPR021904 Protein of unknown function DUF3516 A4G23_RS02415 2c0d7812da1fa72e069afd5620ae190e 837 Gene3D G3DSA:3.40.50.300 219 377 4.9E-18 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS21345 8b46c6b981fa5adf226e2e88117f979b 151 Pfam PF09278 MerR, DNA binding 53 118 1.1E-17 T 10-11-2016 IPR015358 Transcription regulator MerR, DNA binding A4G23_RS21345 8b46c6b981fa5adf226e2e88117f979b 151 SMART SM00422 11 79 4.9E-28 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS21345 8b46c6b981fa5adf226e2e88117f979b 151 Gene3D G3DSA:1.10.1660.10 11 64 1.4E-21 T 10-11-2016 A4G23_RS21345 8b46c6b981fa5adf226e2e88117f979b 151 Pfam PF00376 MerR family regulatory protein 12 48 2.0E-14 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS21345 8b46c6b981fa5adf226e2e88117f979b 151 TIGRFAM TIGR01950 SoxR: redox-sensitive transcriptional activator SoxR 10 148 7.9E-62 T 10-11-2016 IPR010211 Redox-sensitive transcriptional activator SoxR GO:0003677|GO:0006355|GO:0006979|GO:0051537 A4G23_RS21345 8b46c6b981fa5adf226e2e88117f979b 151 Gene3D G3DSA:1.10.1660.10 65 131 7.5E-17 T 10-11-2016 A4G23_RS21345 8b46c6b981fa5adf226e2e88117f979b 151 SUPERFAMILY SSF46955 11 132 2.27E-29 T 10-11-2016 IPR009061 Putative DNA-binding domain A4G23_RS21345 8b46c6b981fa5adf226e2e88117f979b 151 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 12 23 1.6E-13 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS21345 8b46c6b981fa5adf226e2e88117f979b 151 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 46 66 1.6E-13 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS21345 8b46c6b981fa5adf226e2e88117f979b 151 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 23 36 1.6E-13 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS14320 460a09714f2b9ee10007d032f0f7623b 72 Pfam PF14013 MT0933-like antitoxin protein 15 60 5.6E-13 T 10-11-2016 IPR028037 Antitoxin Rv0909/MT0933 A4G23_RS01980 041579cf2588d4c969f4686b7d8a8fb9 182 Gene3D G3DSA:3.40.630.30 12 157 1.6E-28 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS01980 041579cf2588d4c969f4686b7d8a8fb9 182 SUPERFAMILY SSF55729 13 161 1.42E-25 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS01980 041579cf2588d4c969f4686b7d8a8fb9 182 Pfam PF13673 Acetyltransferase (GNAT) domain 52 154 1.7E-11 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS10820 e320727a87640a618ca5f5a6ac4a9a9f 593 SUPERFAMILY SSF69318 360 586 4.97E-23 T 10-11-2016 A4G23_RS10820 e320727a87640a618ca5f5a6ac4a9a9f 593 SUPERFAMILY SSF69318 74 408 1.44E-21 T 10-11-2016 A4G23_RS10820 e320727a87640a618ca5f5a6ac4a9a9f 593 Gene3D G3DSA:2.115.10.10 426 491 1.6E-7 T 10-11-2016 IPR023294 Tachylectin 2 A4G23_RS10820 e320727a87640a618ca5f5a6ac4a9a9f 593 Gene3D G3DSA:2.115.10.10 306 424 4.1E-6 T 10-11-2016 IPR023294 Tachylectin 2 A4G23_RS10820 e320727a87640a618ca5f5a6ac4a9a9f 593 Gene3D G3DSA:2.115.10.10 492 592 7.6E-18 T 10-11-2016 IPR023294 Tachylectin 2 A4G23_RS10820 e320727a87640a618ca5f5a6ac4a9a9f 593 Gene3D G3DSA:2.115.10.10 175 305 1.9E-19 T 10-11-2016 IPR023294 Tachylectin 2 A4G23_RS10820 e320727a87640a618ca5f5a6ac4a9a9f 593 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 492 554 3.6E-9 T 10-11-2016 A4G23_RS24175 c911f2ffee25c6f9ce8465e871035662 192 Gene3D G3DSA:3.40.50.360 3 188 9.0E-41 T 10-11-2016 IPR029039 Flavoprotein-like domain A4G23_RS24175 c911f2ffee25c6f9ce8465e871035662 192 Pfam PF02525 Flavodoxin-like fold 3 174 3.4E-33 T 10-11-2016 IPR003680 Flavodoxin-like fold A4G23_RS24175 c911f2ffee25c6f9ce8465e871035662 192 SUPERFAMILY SSF52218 3 189 7.68E-46 T 10-11-2016 IPR029039 Flavoprotein-like domain A4G23_RS02960 78fc0d1ddbb48f9d4d8e740029bdc387 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 249 9.3E-61 T 10-11-2016 A4G23_RS02960 78fc0d1ddbb48f9d4d8e740029bdc387 252 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 184 3.7E-6 T 10-11-2016 A4G23_RS02960 78fc0d1ddbb48f9d4d8e740029bdc387 252 Gene3D G3DSA:3.40.50.720 2 249 6.4E-81 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS02960 78fc0d1ddbb48f9d4d8e740029bdc387 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 4.1E-40 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS02960 78fc0d1ddbb48f9d4d8e740029bdc387 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 4.1E-40 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS02960 78fc0d1ddbb48f9d4d8e740029bdc387 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 4.1E-40 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS02960 78fc0d1ddbb48f9d4d8e740029bdc387 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 4.1E-40 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS02960 78fc0d1ddbb48f9d4d8e740029bdc387 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 4.1E-40 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS02960 78fc0d1ddbb48f9d4d8e740029bdc387 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 4.1E-40 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS02960 78fc0d1ddbb48f9d4d8e740029bdc387 252 SUPERFAMILY SSF51735 6 249 1.22E-77 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS02960 78fc0d1ddbb48f9d4d8e740029bdc387 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 8.0E-10 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS02960 78fc0d1ddbb48f9d4d8e740029bdc387 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 8.0E-10 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS02960 78fc0d1ddbb48f9d4d8e740029bdc387 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 8.0E-10 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS23075 f34bbd5f0a2da21ac3a206da6afb1770 556 TIGRFAM TIGR02401 trehalose_TreY: malto-oligosyltrehalose synthase 9 555 1.8E-203 T 10-11-2016 IPR012767 Malto-oligosyltrehalose synthase MetaCyc: PWY-2661 A4G23_RS23075 f34bbd5f0a2da21ac3a206da6afb1770 556 Gene3D G3DSA:3.20.20.80 22 96 1.1E-52 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS23075 f34bbd5f0a2da21ac3a206da6afb1770 556 Gene3D G3DSA:3.20.20.80 217 316 1.1E-52 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS23075 f34bbd5f0a2da21ac3a206da6afb1770 556 Gene3D G3DSA:3.20.20.80 491 555 1.1E-52 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS23075 f34bbd5f0a2da21ac3a206da6afb1770 556 SMART SM00642 19 379 4.6E-6 T 10-11-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A4G23_RS23075 f34bbd5f0a2da21ac3a206da6afb1770 556 Pfam PF00128 Alpha amylase, catalytic domain 30 104 2.3E-14 T 10-11-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A4G23_RS23075 f34bbd5f0a2da21ac3a206da6afb1770 556 Gene3D G3DSA:3.30.1590.10 97 216 1.1E-36 T 10-11-2016 A4G23_RS23075 f34bbd5f0a2da21ac3a206da6afb1770 556 SUPERFAMILY SSF51445 9 552 2.34E-88 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS08405 180c38af71272c8e16b476033b164548 295 Gene3D G3DSA:2.30.110.10 167 258 1.3E-15 T 10-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 A4G23_RS08405 180c38af71272c8e16b476033b164548 295 SUPERFAMILY SSF50475 167 259 1.25E-9 T 10-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 A4G23_RS08405 180c38af71272c8e16b476033b164548 295 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 169 258 1.8E-16 T 10-11-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 A4G23_RS05930 90777f2fd12a3253970f6c04a2900721 259 Pfam PF00089 Trypsin 39 252 2.9E-54 T 10-11-2016 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 A4G23_RS05930 90777f2fd12a3253970f6c04a2900721 259 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 116 130 4.9E-13 T 10-11-2016 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 A4G23_RS05930 90777f2fd12a3253970f6c04a2900721 259 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 61 76 4.9E-13 T 10-11-2016 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 A4G23_RS05930 90777f2fd12a3253970f6c04a2900721 259 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 201 213 4.9E-13 T 10-11-2016 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 A4G23_RS05930 90777f2fd12a3253970f6c04a2900721 259 Gene3D G3DSA:2.40.10.10 39 68 1.2E-15 T 10-11-2016 A4G23_RS05930 90777f2fd12a3253970f6c04a2900721 259 SMART SM00020 38 252 4.6E-71 T 10-11-2016 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 A4G23_RS05930 90777f2fd12a3253970f6c04a2900721 259 Gene3D G3DSA:2.40.10.10 69 254 8.3E-54 T 10-11-2016 A4G23_RS05930 90777f2fd12a3253970f6c04a2900721 259 SUPERFAMILY SSF50494 27 254 6.49E-67 T 10-11-2016 IPR009003 Peptidase S1, PA clan A4G23_RS05930 90777f2fd12a3253970f6c04a2900721 259 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 202 213 - T 10-11-2016 IPR033116 Serine proteases, trypsin family, serine active site A4G23_RS05930 90777f2fd12a3253970f6c04a2900721 259 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 71 76 - T 10-11-2016 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 A4G23_RS08255 80ada77103a9e4d67d5edfae46a5d90d 729 Pfam PF00905 Penicillin binding protein transpeptidase domain 298 659 3.6E-84 T 10-11-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A4G23_RS08255 80ada77103a9e4d67d5edfae46a5d90d 729 Gene3D G3DSA:3.40.710.10 261 473 8.8E-92 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS08255 80ada77103a9e4d67d5edfae46a5d90d 729 Gene3D G3DSA:3.40.710.10 511 664 8.8E-92 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS08255 80ada77103a9e4d67d5edfae46a5d90d 729 Pfam PF03717 Penicillin-binding Protein dimerisation domain 60 247 2.0E-38 T 10-11-2016 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 A4G23_RS08255 80ada77103a9e4d67d5edfae46a5d90d 729 TIGRFAM TIGR03423 pbp2_mrdA: penicillin-binding protein 2 16 662 4.7E-178 T 10-11-2016 IPR017790 Penicillin-binding protein 2 GO:0016020 A4G23_RS08255 80ada77103a9e4d67d5edfae46a5d90d 729 SUPERFAMILY SSF56519 53 261 7.46E-37 T 10-11-2016 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 A4G23_RS08255 80ada77103a9e4d67d5edfae46a5d90d 729 Gene3D G3DSA:3.90.1310.10 137 259 3.8E-30 T 10-11-2016 A4G23_RS08255 80ada77103a9e4d67d5edfae46a5d90d 729 SUPERFAMILY SSF56601 213 459 8.25E-88 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS08255 80ada77103a9e4d67d5edfae46a5d90d 729 SUPERFAMILY SSF56601 516 666 8.25E-88 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS10050 4d25edb1d338a649e2fb6751076d136d 336 SUPERFAMILY SSF53448 1 244 3.84E-45 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS10050 4d25edb1d338a649e2fb6751076d136d 336 Pfam PF00535 Glycosyl transferase family 2 7 171 5.2E-22 T 10-11-2016 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A4G23_RS10050 4d25edb1d338a649e2fb6751076d136d 336 Gene3D G3DSA:3.90.550.10 5 238 2.7E-38 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS06300 24efa50a36bde05114c70b553c89b773 791 Pfam PF13559 Domain of unknown function (DUF4129) 661 732 9.2E-5 T 10-11-2016 IPR025403 Domain of unknown function DUF4129 A4G23_RS06300 24efa50a36bde05114c70b553c89b773 791 Pfam PF01841 Transglutaminase-like superfamily 434 549 1.1E-23 T 10-11-2016 IPR002931 Transglutaminase-like A4G23_RS06300 24efa50a36bde05114c70b553c89b773 791 SUPERFAMILY SSF54001 414 564 1.54E-32 T 10-11-2016 A4G23_RS06300 24efa50a36bde05114c70b553c89b773 791 Gene3D G3DSA:3.90.260.10 419 566 1.5E-21 T 10-11-2016 IPR002931 Transglutaminase-like A4G23_RS06300 24efa50a36bde05114c70b553c89b773 791 SMART SM00460 481 551 1.7E-21 T 10-11-2016 IPR002931 Transglutaminase-like A4G23_RS15570 8d9b6ee38279074c0f4b09f6b9f740ff 214 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 98 111 3.8E-5 T 10-11-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A4G23_RS15570 8d9b6ee38279074c0f4b09f6b9f740ff 214 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 3.8E-5 T 10-11-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A4G23_RS15570 8d9b6ee38279074c0f4b09f6b9f740ff 214 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 131 147 3.8E-5 T 10-11-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A4G23_RS15570 8d9b6ee38279074c0f4b09f6b9f740ff 214 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 149 169 3.8E-5 T 10-11-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A4G23_RS15570 8d9b6ee38279074c0f4b09f6b9f740ff 214 Gene3D G3DSA:1.10.150.240 18 84 1.5E-13 T 10-11-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 A4G23_RS15570 8d9b6ee38279074c0f4b09f6b9f740ff 214 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 126 184 8.8E-16 T 10-11-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A4G23_RS15570 8d9b6ee38279074c0f4b09f6b9f740ff 214 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 185 4.0E-26 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS15570 8d9b6ee38279074c0f4b09f6b9f740ff 214 SUPERFAMILY SSF56784 2 213 1.93E-52 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS15570 8d9b6ee38279074c0f4b09f6b9f740ff 214 Gene3D G3DSA:3.40.50.1000 89 212 3.7E-41 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS15570 8d9b6ee38279074c0f4b09f6b9f740ff 214 Gene3D G3DSA:3.40.50.1000 1 17 3.7E-41 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS03255 719f0741f70474dfc1bd9150f6ddee3c 124 Hamap MF_01483 RNA polymerase-binding protein RbpA [rbpA]. 16 120 26.449 T 10-11-2016 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 A4G23_RS03255 719f0741f70474dfc1bd9150f6ddee3c 124 Pfam PF13397 RNA polymerase-binding protein 4 107 7.1E-42 T 10-11-2016 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 A4G23_RS15395 12bda9a920a3c4c36e276ed16a49ec26 268 SUPERFAMILY SSF53067 129 264 1.08E-35 T 10-11-2016 A4G23_RS15395 12bda9a920a3c4c36e276ed16a49ec26 268 Pfam PF03309 Type III pantothenate kinase 2 211 1.2E-68 T 10-11-2016 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 A4G23_RS15395 12bda9a920a3c4c36e276ed16a49ec26 268 Gene3D G3DSA:3.30.420.40 1 68 5.3E-5 T 10-11-2016 A4G23_RS15395 12bda9a920a3c4c36e276ed16a49ec26 268 SUPERFAMILY SSF53067 1 127 1.85E-32 T 10-11-2016 A4G23_RS15395 12bda9a920a3c4c36e276ed16a49ec26 268 Gene3D G3DSA:3.30.420.40 99 266 1.6E-49 T 10-11-2016 A4G23_RS15395 12bda9a920a3c4c36e276ed16a49ec26 268 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 265 35.862 T 10-11-2016 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 A4G23_RS15395 12bda9a920a3c4c36e276ed16a49ec26 268 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 2 261 6.0E-75 T 10-11-2016 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 A4G23_RS02830 e6e9bdccf8faccea9d1bb98a5c6649dd 208 Pfam PF01205 Uncharacterized protein family UPF0029 20 124 2.3E-28 T 10-11-2016 IPR001498 Impact, N-terminal A4G23_RS02830 e6e9bdccf8faccea9d1bb98a5c6649dd 208 Gene3D G3DSA:3.30.70.240 138 205 1.9E-12 T 10-11-2016 IPR000640 Translation elongation factor EFG, V domain A4G23_RS02830 e6e9bdccf8faccea9d1bb98a5c6649dd 208 Gene3D G3DSA:3.30.230.30 5 131 3.2E-44 T 10-11-2016 IPR001498 Impact, N-terminal A4G23_RS02830 e6e9bdccf8faccea9d1bb98a5c6649dd 208 Pfam PF09186 Domain of unknown function (DUF1949) 140 194 6.6E-14 T 10-11-2016 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal A4G23_RS02830 e6e9bdccf8faccea9d1bb98a5c6649dd 208 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 1 200 2.0E-56 T 10-11-2016 IPR015796 Impact family, bacterial/archaeal A4G23_RS02830 e6e9bdccf8faccea9d1bb98a5c6649dd 208 SUPERFAMILY SSF54211 2 130 4.93E-40 T 10-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold A4G23_RS02830 e6e9bdccf8faccea9d1bb98a5c6649dd 208 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 79 108 - T 10-11-2016 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site A4G23_RS02830 e6e9bdccf8faccea9d1bb98a5c6649dd 208 SUPERFAMILY SSF54980 138 199 2.85E-15 T 10-11-2016 IPR009022 Elongation factor G, III-V domain A4G23_RS25810 8d9acef6a9313b16504eb5d37d95ad25 554 SMART SM00331 312 535 1.7E-35 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS25810 8d9acef6a9313b16504eb5d37d95ad25 554 Gene3D G3DSA:3.60.40.10 394 533 9.2E-4 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS25810 8d9acef6a9313b16504eb5d37d95ad25 554 Gene3D G3DSA:3.30.450.40 135 292 8.4E-16 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS25810 8d9acef6a9313b16504eb5d37d95ad25 554 SUPERFAMILY SSF81606 327 533 3.66E-7 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS25810 8d9acef6a9313b16504eb5d37d95ad25 554 SUPERFAMILY SSF55781 148 293 1.44E-10 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS25810 8d9acef6a9313b16504eb5d37d95ad25 554 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 343 534 1.2E-41 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS21475 bc790f72afe5659c2fb9dc77bf0b8a5b 446 PIRSF PIRSF000136 10 446 5.8E-117 T 10-11-2016 IPR010031 L-gulonolactone/D-arabinono-1,4-lactone oxidase GO:0016899|GO:0055114 A4G23_RS21475 bc790f72afe5659c2fb9dc77bf0b8a5b 446 Pfam PF01565 FAD binding domain 31 165 3.2E-30 T 10-11-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 A4G23_RS21475 bc790f72afe5659c2fb9dc77bf0b8a5b 446 SUPERFAMILY SSF56176 17 195 2.06E-47 T 10-11-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 A4G23_RS21475 bc790f72afe5659c2fb9dc77bf0b8a5b 446 Gene3D G3DSA:3.30.43.10 17 87 3.5E-23 T 10-11-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 A4G23_RS21475 bc790f72afe5659c2fb9dc77bf0b8a5b 446 TIGRFAM TIGR01679 bact_FAD_ox: FAD-linked oxidoreductase 19 445 8.1E-119 T 10-11-2016 A4G23_RS21475 bc790f72afe5659c2fb9dc77bf0b8a5b 446 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 30 63 - T 10-11-2016 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 A4G23_RS21475 bc790f72afe5659c2fb9dc77bf0b8a5b 446 Pfam PF04030 D-arabinono-1,4-lactone oxidase 189 443 1.6E-80 T 10-11-2016 IPR007173 D-arabinono-1,4-lactone oxidase GO:0003885|GO:0016020|GO:0055114 A4G23_RS21475 bc790f72afe5659c2fb9dc77bf0b8a5b 446 Gene3D G3DSA:3.30.465.10 88 195 7.7E-31 T 10-11-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 A4G23_RS05260 f9572370c43ca4d301739611e4a8f3cd 134 Gene3D G3DSA:3.10.180.10 6 127 9.0E-26 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS05260 f9572370c43ca4d301739611e4a8f3cd 134 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 11 124 3.4E-7 T 10-11-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4G23_RS05260 f9572370c43ca4d301739611e4a8f3cd 134 SUPERFAMILY SSF54593 7 126 1.24E-22 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS02865 6a8ba80ba10721a4714130bb7ea9dc9b 247 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 166 194 - T 10-11-2016 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 A4G23_RS02865 6a8ba80ba10721a4714130bb7ea9dc9b 247 Gene3D G3DSA:2.160.10.10 64 214 2.0E-38 T 10-11-2016 A4G23_RS02865 6a8ba80ba10721a4714130bb7ea9dc9b 247 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 158 192 4.6E-10 T 10-11-2016 IPR001451 Hexapeptide repeat A4G23_RS02865 6a8ba80ba10721a4714130bb7ea9dc9b 247 SUPERFAMILY SSF51161 69 213 3.77E-35 T 10-11-2016 IPR011004 Trimeric LpxA-like A4G23_RS12150 36f00f261356cc7da125c988cf25a53d 585 Pfam PF07681 DoxX 252 353 2.8E-11 T 10-11-2016 IPR032808 DoxX family A4G23_RS24465 d1d1f4d3dc7c1a929ff9278db915f104 216 Pfam PF09335 SNARE associated Golgi protein 38 167 2.5E-10 T 10-11-2016 IPR032816 SNARE associated Golgi protein A4G23_RS13180 76060026082d62e95b20c5a898fc647e 562 Pfam PF00069 Protein kinase domain 20 291 2.2E-48 T 10-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4G23_RS13180 76060026082d62e95b20c5a898fc647e 562 Gene3D G3DSA:3.30.200.20 12 111 3.8E-25 T 10-11-2016 A4G23_RS13180 76060026082d62e95b20c5a898fc647e 562 SMART SM00220 20 295 3.9E-63 T 10-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4G23_RS13180 76060026082d62e95b20c5a898fc647e 562 Pfam PF03793 PASTA domain 494 556 2.2E-8 T 10-11-2016 IPR005543 PASTA domain A4G23_RS13180 76060026082d62e95b20c5a898fc647e 562 Gene3D G3DSA:1.10.510.10 114 293 7.3E-47 T 10-11-2016 A4G23_RS13180 76060026082d62e95b20c5a898fc647e 562 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 155 167 - T 10-11-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 A4G23_RS13180 76060026082d62e95b20c5a898fc647e 562 SMART SM00740 489 557 7.0E-9 T 10-11-2016 IPR005543 PASTA domain A4G23_RS13180 76060026082d62e95b20c5a898fc647e 562 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 26 49 - T 10-11-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 A4G23_RS13180 76060026082d62e95b20c5a898fc647e 562 SUPERFAMILY SSF56112 16 358 1.11E-71 T 10-11-2016 IPR011009 Protein kinase-like domain A4G23_RS05505 582f2d0995c651749c91b716f4d814e2 611 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 311 602 4.1E-11 T 10-11-2016 IPR005135 Endonuclease/exonuclease/phosphatase A4G23_RS05505 582f2d0995c651749c91b716f4d814e2 611 Gene3D G3DSA:3.60.10.10 308 609 9.1E-32 T 10-11-2016 IPR005135 Endonuclease/exonuclease/phosphatase A4G23_RS05505 582f2d0995c651749c91b716f4d814e2 611 SUPERFAMILY SSF56219 309 609 2.64E-27 T 10-11-2016 IPR005135 Endonuclease/exonuclease/phosphatase A4G23_RS15075 a5d4584c6e8b0fa7ab4710814d8250e5 411 Pfam PF04932 O-Antigen ligase 188 344 1.5E-13 T 10-11-2016 IPR007016 O-antigen ligase-related A4G23_RS22475 d8369e62cd51f7e26b174355cf3e4d16 803 Gene3D G3DSA:1.10.1200.10 621 705 3.2E-15 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS22475 d8369e62cd51f7e26b174355cf3e4d16 803 Gene3D G3DSA:3.40.50.980 230 367 2.3E-35 T 10-11-2016 A4G23_RS22475 d8369e62cd51f7e26b174355cf3e4d16 803 Pfam PF00550 Phosphopantetheine attachment site 634 677 7.0E-7 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS22475 d8369e62cd51f7e26b174355cf3e4d16 803 SUPERFAMILY SSF51735 742 786 1.3E-8 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS22475 d8369e62cd51f7e26b174355cf3e4d16 803 Pfam PF00501 AMP-binding enzyme 61 460 8.3E-91 T 10-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A4G23_RS22475 d8369e62cd51f7e26b174355cf3e4d16 803 SUPERFAMILY SSF56801 560 642 4.71E-138 T 10-11-2016 A4G23_RS22475 d8369e62cd51f7e26b174355cf3e4d16 803 SUPERFAMILY SSF56801 53 513 4.71E-138 T 10-11-2016 A4G23_RS22475 d8369e62cd51f7e26b174355cf3e4d16 803 Gene3D G3DSA:2.30.38.10 368 449 1.7E-23 T 10-11-2016 A4G23_RS22475 d8369e62cd51f7e26b174355cf3e4d16 803 ProSitePatterns PS00455 Putative AMP-binding domain signature. 200 211 - T 10-11-2016 IPR020845 AMP-binding, conserved site A4G23_RS22475 d8369e62cd51f7e26b174355cf3e4d16 803 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 82 484 2.5E-120 T 10-11-2016 IPR010071 Amino acid adenylation domain A4G23_RS22475 d8369e62cd51f7e26b174355cf3e4d16 803 Gene3D G3DSA:3.30.300.30 556 609 9.2E-25 T 10-11-2016 A4G23_RS22475 d8369e62cd51f7e26b174355cf3e4d16 803 Gene3D G3DSA:3.30.300.30 454 503 9.2E-25 T 10-11-2016 A4G23_RS22475 d8369e62cd51f7e26b174355cf3e4d16 803 SUPERFAMILY SSF47336 623 699 8.77E-10 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS22475 d8369e62cd51f7e26b174355cf3e4d16 803 Gene3D G3DSA:3.40.50.980 54 222 9.3E-47 T 10-11-2016 A4G23_RS22475 d8369e62cd51f7e26b174355cf3e4d16 803 Pfam PF07993 Male sterility protein 747 795 2.0E-10 T 10-11-2016 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 A4G23_RS22475 d8369e62cd51f7e26b174355cf3e4d16 803 Gene3D G3DSA:3.40.50.720 744 786 9.9E-9 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS05485 473f8a33efbe7ac8185acaa318974b95 317 Pfam PF12833 Helix-turn-helix domain 228 310 2.1E-25 T 10-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4G23_RS05485 473f8a33efbe7ac8185acaa318974b95 317 Pfam PF14525 AraC-binding-like domain 21 186 2.4E-35 T 10-11-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 A4G23_RS05485 473f8a33efbe7ac8185acaa318974b95 317 Gene3D G3DSA:1.10.10.60 260 307 5.6E-6 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS05485 473f8a33efbe7ac8185acaa318974b95 317 SMART SM00342 222 309 7.8E-27 T 10-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4G23_RS05485 473f8a33efbe7ac8185acaa318974b95 317 SUPERFAMILY SSF46689 208 256 9.86E-6 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS05485 473f8a33efbe7ac8185acaa318974b95 317 Gene3D G3DSA:1.10.10.60 204 259 3.1E-11 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS24075 109351fb283d0cea8b0a0fdbe8138e7c 555 Gene3D G3DSA:3.40.50.1820 266 371 2.8E-51 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS24075 109351fb283d0cea8b0a0fdbe8138e7c 555 Gene3D G3DSA:3.40.50.1820 55 214 2.8E-51 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS24075 109351fb283d0cea8b0a0fdbe8138e7c 555 Gene3D G3DSA:2.60.120.260 372 553 8.3E-16 T 10-11-2016 IPR008979 Galactose-binding domain-like A4G23_RS24075 109351fb283d0cea8b0a0fdbe8138e7c 555 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 81 319 1.9E-34 T 10-11-2016 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 A4G23_RS24075 109351fb283d0cea8b0a0fdbe8138e7c 555 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 350 539 7.2E-20 T 10-11-2016 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 A4G23_RS24075 109351fb283d0cea8b0a0fdbe8138e7c 555 SMART SM00939 338 548 5.5E-28 T 10-11-2016 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 A4G23_RS24075 109351fb283d0cea8b0a0fdbe8138e7c 555 SUPERFAMILY SSF49785 368 553 1.74E-18 T 10-11-2016 IPR008979 Galactose-binding domain-like A4G23_RS24075 109351fb283d0cea8b0a0fdbe8138e7c 555 SUPERFAMILY SSF53474 75 374 1.4E-51 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS02540 4f76a0bacb758a5737b13fd9a8500b85 254 SUPERFAMILY SSF69593 10 217 3.01E-55 T 10-11-2016 A4G23_RS02540 4f76a0bacb758a5737b13fd9a8500b85 254 Pfam PF01553 Acyltransferase 22 151 1.2E-23 T 10-11-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 A4G23_RS02540 4f76a0bacb758a5737b13fd9a8500b85 254 Gene3D G3DSA:3.40.1130.10 7 205 1.8E-34 T 10-11-2016 A4G23_RS02540 4f76a0bacb758a5737b13fd9a8500b85 254 SMART SM00563 35 154 1.2E-41 T 10-11-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 A4G23_RS09120 4580969125599e8140eeba5346a76415 973 SMART SM00637 45 144 5.2E-41 T 10-11-2016 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 A4G23_RS09120 4580969125599e8140eeba5346a76415 973 Gene3D G3DSA:4.10.870.10 887 950 1.0E-30 T 10-11-2016 IPR027390 Endoglucanase F, domain 3 A4G23_RS09120 4580969125599e8140eeba5346a76415 973 SUPERFAMILY SSF48208 339 972 8.5E-294 T 10-11-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 A4G23_RS09120 4580969125599e8140eeba5346a76415 973 SUPERFAMILY SSF49384 44 145 8.37E-29 T 10-11-2016 IPR008965 Carbohydrate-binding domain GO:0030246 A4G23_RS09120 4580969125599e8140eeba5346a76415 973 Gene3D G3DSA:2.60.40.290 44 146 4.1E-33 T 10-11-2016 IPR012291 Cellulose-binding family II/chitobiase, carbohydrate-binding domain GO:0004553|GO:0030247 A4G23_RS09120 4580969125599e8140eeba5346a76415 973 PRINTS PR00844 Glycosyl hydrolase family 48 signature 514 538 5.0E-110 T 10-11-2016 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 A4G23_RS09120 4580969125599e8140eeba5346a76415 973 PRINTS PR00844 Glycosyl hydrolase family 48 signature 393 410 5.0E-110 T 10-11-2016 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 A4G23_RS09120 4580969125599e8140eeba5346a76415 973 PRINTS PR00844 Glycosyl hydrolase family 48 signature 748 774 5.0E-110 T 10-11-2016 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 A4G23_RS09120 4580969125599e8140eeba5346a76415 973 PRINTS PR00844 Glycosyl hydrolase family 48 signature 632 651 5.0E-110 T 10-11-2016 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 A4G23_RS09120 4580969125599e8140eeba5346a76415 973 PRINTS PR00844 Glycosyl hydrolase family 48 signature 905 933 5.0E-110 T 10-11-2016 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 A4G23_RS09120 4580969125599e8140eeba5346a76415 973 PRINTS PR00844 Glycosyl hydrolase family 48 signature 559 586 5.0E-110 T 10-11-2016 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 A4G23_RS09120 4580969125599e8140eeba5346a76415 973 PRINTS PR00844 Glycosyl hydrolase family 48 signature 367 392 5.0E-110 T 10-11-2016 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 A4G23_RS09120 4580969125599e8140eeba5346a76415 973 PRINTS PR00844 Glycosyl hydrolase family 48 signature 803 823 5.0E-110 T 10-11-2016 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 A4G23_RS09120 4580969125599e8140eeba5346a76415 973 PRINTS PR00844 Glycosyl hydrolase family 48 signature 702 725 5.0E-110 T 10-11-2016 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 A4G23_RS09120 4580969125599e8140eeba5346a76415 973 Pfam PF02011 Glycosyl hydrolase family 48 344 971 0.0 T 10-11-2016 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 A4G23_RS09120 4580969125599e8140eeba5346a76415 973 Gene3D G3DSA:1.50.10.10 471 486 2.8E-205 T 10-11-2016 IPR012341 Six-hairpin glycosidase GO:0003824 A4G23_RS09120 4580969125599e8140eeba5346a76415 973 Gene3D G3DSA:1.50.10.10 566 884 2.8E-205 T 10-11-2016 IPR012341 Six-hairpin glycosidase GO:0003824 A4G23_RS09120 4580969125599e8140eeba5346a76415 973 Gene3D G3DSA:1.50.10.10 340 425 2.8E-205 T 10-11-2016 IPR012341 Six-hairpin glycosidase GO:0003824 A4G23_RS09120 4580969125599e8140eeba5346a76415 973 Gene3D G3DSA:1.50.10.10 951 972 2.8E-205 T 10-11-2016 IPR012341 Six-hairpin glycosidase GO:0003824 A4G23_RS09120 4580969125599e8140eeba5346a76415 973 Pfam PF00553 Cellulose binding domain 45 144 4.6E-26 T 10-11-2016 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 A4G23_RS13240 024b7e44bb8b4ada41ee640a28bee534 380 Pfam PF00676 Dehydrogenase E1 component 69 327 3.5E-74 T 10-11-2016 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 A4G23_RS13240 024b7e44bb8b4ada41ee640a28bee534 380 Gene3D G3DSA:3.40.50.970 37 366 8.3E-118 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS13240 024b7e44bb8b4ada41ee640a28bee534 380 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 45 366 2.6E-127 T 10-11-2016 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 A4G23_RS13240 024b7e44bb8b4ada41ee640a28bee534 380 SUPERFAMILY SSF52518 47 369 8.4E-94 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS24665 04fe93606746fd6d97a90b916659245f 447 Gene3D G3DSA:3.90.110.10 164 440 3.4E-94 T 10-11-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 A4G23_RS24665 04fe93606746fd6d97a90b916659245f 447 SUPERFAMILY SSF51735 1 163 5.44E-46 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS24665 04fe93606746fd6d97a90b916659245f 447 SUPERFAMILY SSF56327 164 442 4.17E-63 T 10-11-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 A4G23_RS24665 04fe93606746fd6d97a90b916659245f 447 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 190 423 5.4E-47 T 10-11-2016 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 A4G23_RS24665 04fe93606746fd6d97a90b916659245f 447 PRINTS PR00732 Glycosyl hydrolase family 4 signature 92 105 2.0E-38 T 10-11-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A4G23_RS24665 04fe93606746fd6d97a90b916659245f 447 PRINTS PR00732 Glycosyl hydrolase family 4 signature 71 87 2.0E-38 T 10-11-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A4G23_RS24665 04fe93606746fd6d97a90b916659245f 447 PRINTS PR00732 Glycosyl hydrolase family 4 signature 186 198 2.0E-38 T 10-11-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A4G23_RS24665 04fe93606746fd6d97a90b916659245f 447 PRINTS PR00732 Glycosyl hydrolase family 4 signature 135 152 2.0E-38 T 10-11-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A4G23_RS24665 04fe93606746fd6d97a90b916659245f 447 PRINTS PR00732 Glycosyl hydrolase family 4 signature 160 171 2.0E-38 T 10-11-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A4G23_RS24665 04fe93606746fd6d97a90b916659245f 447 PRINTS PR00732 Glycosyl hydrolase family 4 signature 106 126 2.0E-38 T 10-11-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A4G23_RS24665 04fe93606746fd6d97a90b916659245f 447 PRINTS PR00732 Glycosyl hydrolase family 4 signature 2 17 2.0E-38 T 10-11-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A4G23_RS24665 04fe93606746fd6d97a90b916659245f 447 Gene3D G3DSA:3.40.50.720 1 163 1.2E-58 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS24665 04fe93606746fd6d97a90b916659245f 447 Pfam PF02056 Family 4 glycosyl hydrolase 3 180 3.8E-44 T 10-11-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A4G23_RS24665 04fe93606746fd6d97a90b916659245f 447 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 135 165 - T 10-11-2016 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 A4G23_RS07790 c08a690bd8772172970f7f2303c8aaac 378 Gene3D G3DSA:3.20.20.70 16 254 3.2E-82 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS07790 c08a690bd8772172970f7f2303c8aaac 378 Gene3D G3DSA:1.10.1200.80 262 329 2.0E-18 T 10-11-2016 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 A4G23_RS07790 c08a690bd8772172970f7f2303c8aaac 378 SUPERFAMILY SSF51395 16 327 1.79E-79 T 10-11-2016 A4G23_RS07790 c08a690bd8772172970f7f2303c8aaac 378 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 9 328 1.1E-111 T 10-11-2016 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 A4G23_RS07790 c08a690bd8772172970f7f2303c8aaac 378 Pfam PF01207 Dihydrouridine synthase (Dus) 19 325 2.1E-93 T 10-11-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 A4G23_RS07790 c08a690bd8772172970f7f2303c8aaac 378 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 103 121 - T 10-11-2016 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 A4G23_RS07790 c08a690bd8772172970f7f2303c8aaac 378 PIRSF PIRSF006621 7 339 1.7E-99 T 10-11-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 A4G23_RS09820 6efd6df1ef9551330f11e4fcc6bc033d 936 Gene3D G3DSA:3.40.50.300 409 626 6.1E-95 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS09820 6efd6df1ef9551330f11e4fcc6bc033d 936 SMART SM00958 226 350 1.0E-66 T 10-11-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 A4G23_RS09820 6efd6df1ef9551330f11e4fcc6bc033d 936 Pfam PF01043 SecA preprotein cross-linking domain 231 350 1.3E-34 T 10-11-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 A4G23_RS09820 6efd6df1ef9551330f11e4fcc6bc033d 936 PRINTS PR00906 SecA protein signature 368 385 1.3E-72 T 10-11-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A4G23_RS09820 6efd6df1ef9551330f11e4fcc6bc033d 936 PRINTS PR00906 SecA protein signature 115 125 1.3E-72 T 10-11-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A4G23_RS09820 6efd6df1ef9551330f11e4fcc6bc033d 936 PRINTS PR00906 SecA protein signature 331 353 1.3E-72 T 10-11-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A4G23_RS09820 6efd6df1ef9551330f11e4fcc6bc033d 936 PRINTS PR00906 SecA protein signature 405 418 1.3E-72 T 10-11-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A4G23_RS09820 6efd6df1ef9551330f11e4fcc6bc033d 936 PRINTS PR00906 SecA protein signature 99 113 1.3E-72 T 10-11-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A4G23_RS09820 6efd6df1ef9551330f11e4fcc6bc033d 936 PRINTS PR00906 SecA protein signature 61 85 1.3E-72 T 10-11-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A4G23_RS09820 6efd6df1ef9551330f11e4fcc6bc033d 936 PRINTS PR00906 SecA protein signature 168 188 1.3E-72 T 10-11-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A4G23_RS09820 6efd6df1ef9551330f11e4fcc6bc033d 936 ProSitePatterns PS01312 SecA family signature. 492 507 - T 10-11-2016 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 A4G23_RS09820 6efd6df1ef9551330f11e4fcc6bc033d 936 Pfam PF07517 SecA DEAD-like domain 6 393 6.0E-129 T 10-11-2016 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 A4G23_RS09820 6efd6df1ef9551330f11e4fcc6bc033d 936 Gene3D G3DSA:3.40.50.300 361 408 3.3E-122 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS09820 6efd6df1ef9551330f11e4fcc6bc033d 936 Gene3D G3DSA:3.40.50.300 3 226 3.3E-122 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS09820 6efd6df1ef9551330f11e4fcc6bc033d 936 SUPERFAMILY SSF81767 225 360 4.58E-41 T 10-11-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 A4G23_RS09820 6efd6df1ef9551330f11e4fcc6bc033d 936 SMART SM00957 4 394 8.1E-285 T 10-11-2016 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 A4G23_RS09820 6efd6df1ef9551330f11e4fcc6bc033d 936 SUPERFAMILY SSF52540 360 407 9.25E-81 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS09820 6efd6df1ef9551330f11e4fcc6bc033d 936 SUPERFAMILY SSF52540 4 226 9.25E-81 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS09820 6efd6df1ef9551330f11e4fcc6bc033d 936 SUPERFAMILY SSF81886 627 850 4.19E-74 T 10-11-2016 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 A4G23_RS09820 6efd6df1ef9551330f11e4fcc6bc033d 936 Gene3D G3DSA:1.10.3060.10 655 839 3.1E-58 T 10-11-2016 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 A4G23_RS09820 6efd6df1ef9551330f11e4fcc6bc033d 936 Hamap MF_01382 Protein translocase subunit SecA [secA]. 3 841 20.089 T 10-11-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A4G23_RS09820 6efd6df1ef9551330f11e4fcc6bc033d 936 SUPERFAMILY SSF52540 408 625 7.59E-60 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS09820 6efd6df1ef9551330f11e4fcc6bc033d 936 Pfam PF07516 SecA Wing and Scaffold domain 624 838 7.5E-66 T 10-11-2016 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 A4G23_RS09820 6efd6df1ef9551330f11e4fcc6bc033d 936 Gene3D G3DSA:3.90.1440.10 228 360 2.9E-45 T 10-11-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 A4G23_RS09820 6efd6df1ef9551330f11e4fcc6bc033d 936 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 26 827 0.0 T 10-11-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A4G23_RS08225 8903df615de11b57e6338a369e941546 640 SMART SM00729 263 486 4.9E-30 T 10-11-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 A4G23_RS08225 8903df615de11b57e6338a369e941546 640 TIGRFAM TIGR03960 rSAM_fuse_unch: radical SAM family uncharacterized protein 11 617 9.0E-214 T 10-11-2016 IPR023862 Conserved hypothetical protein CHP03960, radical SAM A4G23_RS08225 8903df615de11b57e6338a369e941546 640 Gene3D G3DSA:3.80.30.20 262 491 1.5E-44 T 10-11-2016 IPR023404 Radical SAM, alpha/beta horseshoe A4G23_RS08225 8903df615de11b57e6338a369e941546 640 Pfam PF04055 Radical SAM superfamily 267 432 2.7E-15 T 10-11-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 A4G23_RS08225 8903df615de11b57e6338a369e941546 640 SUPERFAMILY SSF102114 231 634 3.01E-52 T 10-11-2016 A4G23_RS13535 9d8139fc791120be7435d2cd62b6c070 578 Gene3D G3DSA:2.60.120.260 437 551 7.8E-7 T 10-11-2016 IPR008979 Galactose-binding domain-like A4G23_RS13535 9d8139fc791120be7435d2cd62b6c070 578 SUPERFAMILY SSF49785 441 549 1.84E-5 T 10-11-2016 IPR008979 Galactose-binding domain-like A4G23_RS13535 9d8139fc791120be7435d2cd62b6c070 578 Gene3D G3DSA:1.10.510.10 135 208 2.4E-8 T 10-11-2016 A4G23_RS13535 9d8139fc791120be7435d2cd62b6c070 578 SUPERFAMILY SSF56112 87 249 9.37E-14 T 10-11-2016 IPR011009 Protein kinase-like domain A4G23_RS13535 9d8139fc791120be7435d2cd62b6c070 578 Gene3D G3DSA:3.30.200.20 63 134 9.9E-4 T 10-11-2016 A4G23_RS26290 9da9e3031e9ca61f9542ff25f6d70d5b 937 SMART SM00421 875 932 2.2E-8 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS26290 9da9e3031e9ca61f9542ff25f6d70d5b 937 SUPERFAMILY SSF52540 94 223 2.93E-8 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS26290 9da9e3031e9ca61f9542ff25f6d70d5b 937 SUPERFAMILY SSF52540 1 51 2.93E-8 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS26290 9da9e3031e9ca61f9542ff25f6d70d5b 937 Gene3D G3DSA:1.10.10.10 879 930 3.4E-15 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS26290 9da9e3031e9ca61f9542ff25f6d70d5b 937 Pfam PF00196 Bacterial regulatory proteins, luxR family 879 929 1.8E-8 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS26290 9da9e3031e9ca61f9542ff25f6d70d5b 937 Pfam PF13191 AAA ATPase domain 1 142 2.1E-12 T 10-11-2016 A4G23_RS26290 9da9e3031e9ca61f9542ff25f6d70d5b 937 Gene3D G3DSA:1.25.40.10 365 570 1.1E-5 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS26290 9da9e3031e9ca61f9542ff25f6d70d5b 937 SUPERFAMILY SSF46894 870 930 5.1E-13 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS15625 1d27cd1b7eefa2088b2c98f73ac1b98e 452 PIRSF PIRSF000445 1 440 1.0E-132 T 10-11-2016 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A4G23_RS15625 1d27cd1b7eefa2088b2c98f73ac1b98e 452 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 329 428 6.9E-20 T 10-11-2016 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A4G23_RS15625 1d27cd1b7eefa2088b2c98f73ac1b98e 452 SUPERFAMILY SSF51735 182 314 4.56E-22 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS15625 1d27cd1b7eefa2088b2c98f73ac1b98e 452 SUPERFAMILY SSF69742 1 158 4.32E-44 T 10-11-2016 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A4G23_RS15625 1d27cd1b7eefa2088b2c98f73ac1b98e 452 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 4 429 1.1E-115 T 10-11-2016 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A4G23_RS15625 1d27cd1b7eefa2088b2c98f73ac1b98e 452 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 426 25.516 T 10-11-2016 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A4G23_RS15625 1d27cd1b7eefa2088b2c98f73ac1b98e 452 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 184 316 2.4E-30 T 10-11-2016 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase A4G23_RS15625 1d27cd1b7eefa2088b2c98f73ac1b98e 452 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 6 156 9.5E-45 T 10-11-2016 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A4G23_RS15625 1d27cd1b7eefa2088b2c98f73ac1b98e 452 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 99 122 - T 10-11-2016 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A4G23_RS15625 1d27cd1b7eefa2088b2c98f73ac1b98e 452 SUPERFAMILY SSF69075 329 429 3.14E-15 T 10-11-2016 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A4G23_RS15625 1d27cd1b7eefa2088b2c98f73ac1b98e 452 Gene3D G3DSA:3.40.50.720 184 316 2.2E-25 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS03390 ff47ad634070101cca776064e9cfb787 303 Pfam PF04542 Sigma-70 region 2 8 71 1.5E-17 T 10-11-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS03390 ff47ad634070101cca776064e9cfb787 303 Gene3D G3DSA:3.10.450.50 169 286 2.2E-16 T 10-11-2016 IPR032710 NTF2-like domain A4G23_RS03390 ff47ad634070101cca776064e9cfb787 303 SUPERFAMILY SSF88946 7 85 3.06E-14 T 10-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS03390 ff47ad634070101cca776064e9cfb787 303 Pfam PF08281 Sigma-70, region 4 107 157 1.9E-9 T 10-11-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS03390 ff47ad634070101cca776064e9cfb787 303 Pfam PF12680 SnoaL-like domain 178 273 7.1E-7 T 10-11-2016 IPR009959 Polyketide cyclase SnoaL-like domain A4G23_RS03390 ff47ad634070101cca776064e9cfb787 303 Gene3D G3DSA:1.10.1740.10 6 73 4.5E-14 T 10-11-2016 A4G23_RS03390 ff47ad634070101cca776064e9cfb787 303 Gene3D G3DSA:1.10.10.10 105 159 1.9E-9 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS03390 ff47ad634070101cca776064e9cfb787 303 TIGRFAM TIGR02957 SigX4: RNA polymerase sigma-70 factor, TIGR02957 family 6 287 3.2E-101 T 10-11-2016 IPR014303 RNA polymerase sigma-70, ECF type A4G23_RS03390 ff47ad634070101cca776064e9cfb787 303 SUPERFAMILY SSF54427 172 288 1.98E-20 T 10-11-2016 IPR032710 NTF2-like domain A4G23_RS03390 ff47ad634070101cca776064e9cfb787 303 SUPERFAMILY SSF88659 79 159 1.08E-11 T 10-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS03390 ff47ad634070101cca776064e9cfb787 303 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 8 159 2.3E-18 T 10-11-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS20705 ca4a19b921f070d06afb99197afae944 292 SUPERFAMILY SSF161098 7 285 6.02E-51 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS20705 ca4a19b921f070d06afb99197afae944 292 Gene3D G3DSA:1.10.3720.10 3 283 1.5E-50 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS20705 ca4a19b921f070d06afb99197afae944 292 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 281 8.1E-14 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS22590 35b1bfa9b6e5781e58239e258f6189ea 678 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 541 613 3.5E-11 T 10-11-2016 IPR000772 Ricin B, lectin domain A4G23_RS22590 35b1bfa9b6e5781e58239e258f6189ea 678 SUPERFAMILY SSF49265 452 522 9.21E-7 T 10-11-2016 IPR003961 Fibronectin type III GO:0005515 A4G23_RS22590 35b1bfa9b6e5781e58239e258f6189ea 678 Gene3D G3DSA:2.80.10.50 543 676 4.0E-19 T 10-11-2016 A4G23_RS22590 35b1bfa9b6e5781e58239e258f6189ea 678 Gene3D G3DSA:2.60.40.10 447 518 4.5E-5 T 10-11-2016 IPR013783 Immunoglobulin-like fold A4G23_RS22590 35b1bfa9b6e5781e58239e258f6189ea 678 SUPERFAMILY SSF50370 539 675 9.68E-25 T 10-11-2016 IPR000772 Ricin B, lectin domain A4G23_RS22590 35b1bfa9b6e5781e58239e258f6189ea 678 Pfam PF13582 Metallo-peptidase family M12B Reprolysin-like 220 338 8.8E-6 T 10-11-2016 A4G23_RS22590 35b1bfa9b6e5781e58239e258f6189ea 678 SMART SM00458 541 676 1.5E-10 T 10-11-2016 IPR000772 Ricin B, lectin domain A4G23_RS22590 35b1bfa9b6e5781e58239e258f6189ea 678 Gene3D G3DSA:3.40.390.10 292 368 1.1E-4 T 10-11-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 A4G23_RS22590 35b1bfa9b6e5781e58239e258f6189ea 678 SUPERFAMILY SSF55486 289 388 2.05E-8 T 10-11-2016 A4G23_RS01560 5a3334dea223cba63cd2e1202f8b33a7 126 Pfam PF01638 HxlR-like helix-turn-helix 28 115 5.6E-26 T 10-11-2016 IPR002577 Helix-turn-helix, HxlR type A4G23_RS01560 5a3334dea223cba63cd2e1202f8b33a7 126 Gene3D G3DSA:1.10.10.10 11 124 9.2E-38 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS01560 5a3334dea223cba63cd2e1202f8b33a7 126 SUPERFAMILY SSF46785 23 124 6.71E-28 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS08905 99137ac66208cacfc6b66d0e2626c95c 264 Gene3D G3DSA:1.10.260.40 5 58 3.1E-14 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS08905 99137ac66208cacfc6b66d0e2626c95c 264 Pfam PF13560 Helix-turn-helix domain 6 58 5.2E-13 T 10-11-2016 A4G23_RS08905 99137ac66208cacfc6b66d0e2626c95c 264 SMART SM00530 8 63 2.1E-11 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS08905 99137ac66208cacfc6b66d0e2626c95c 264 SUPERFAMILY SSF47413 3 58 1.94E-12 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS21750 4f20c0824ef9f4dab982243f5584ad72 67 Gene3D G3DSA:2.40.50.140 1 66 3.5E-29 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS21750 4f20c0824ef9f4dab982243f5584ad72 67 SMART SM00357 3 67 8.3E-30 T 10-11-2016 IPR011129 Cold shock protein GO:0003676 A4G23_RS21750 4f20c0824ef9f4dab982243f5584ad72 67 PRINTS PR00050 Cold shock protein signature 40 58 3.4E-17 T 10-11-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4G23_RS21750 4f20c0824ef9f4dab982243f5584ad72 67 PRINTS PR00050 Cold shock protein signature 4 19 3.4E-17 T 10-11-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4G23_RS21750 4f20c0824ef9f4dab982243f5584ad72 67 PRINTS PR00050 Cold shock protein signature 25 34 3.4E-17 T 10-11-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4G23_RS21750 4f20c0824ef9f4dab982243f5584ad72 67 PIRSF PIRSF002599 1 67 1.7E-25 T 10-11-2016 IPR012156 Cold shock, CspA GO:0003676 A4G23_RS21750 4f20c0824ef9f4dab982243f5584ad72 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 10-11-2016 IPR019844 Cold-shock conserved site A4G23_RS21750 4f20c0824ef9f4dab982243f5584ad72 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 3.7E-29 T 10-11-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4G23_RS21750 4f20c0824ef9f4dab982243f5584ad72 67 SUPERFAMILY SSF50249 1 66 9.55E-24 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS17630 37bbc91628ba9f51a7aef0591acd93ab 301 Gene3D G3DSA:3.40.190.10 179 266 1.4E-30 T 10-11-2016 A4G23_RS17630 37bbc91628ba9f51a7aef0591acd93ab 301 Gene3D G3DSA:1.10.10.10 8 87 1.2E-24 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS17630 37bbc91628ba9f51a7aef0591acd93ab 301 Gene3D G3DSA:3.40.190.10 93 178 1.4E-22 T 10-11-2016 A4G23_RS17630 37bbc91628ba9f51a7aef0591acd93ab 301 SUPERFAMILY SSF46785 8 86 6.19E-20 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS17630 37bbc91628ba9f51a7aef0591acd93ab 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 6.1E-7 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS17630 37bbc91628ba9f51a7aef0591acd93ab 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 6.1E-7 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS17630 37bbc91628ba9f51a7aef0591acd93ab 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 6.1E-7 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS17630 37bbc91628ba9f51a7aef0591acd93ab 301 SUPERFAMILY SSF53850 92 295 1.74E-43 T 10-11-2016 A4G23_RS17630 37bbc91628ba9f51a7aef0591acd93ab 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 65 2.6E-20 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS17630 37bbc91628ba9f51a7aef0591acd93ab 301 Pfam PF03466 LysR substrate binding domain 92 291 3.5E-50 T 10-11-2016 IPR005119 LysR, substrate-binding A4G23_RS11160 27edaedbb54b5bd14c0036b072188e0c 567 Pfam PF04820 Tryptophan halogenase 77 208 3.5E-12 T 10-11-2016 IPR006905 Tryptophan halogenase A4G23_RS11160 27edaedbb54b5bd14c0036b072188e0c 567 SUPERFAMILY SSF51905 282 378 3.74E-28 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS11160 27edaedbb54b5bd14c0036b072188e0c 567 SUPERFAMILY SSF51905 3 161 3.74E-28 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS11160 27edaedbb54b5bd14c0036b072188e0c 567 Gene3D G3DSA:3.50.50.60 80 160 1.6E-24 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS11160 27edaedbb54b5bd14c0036b072188e0c 567 Gene3D G3DSA:3.50.50.60 4 48 1.6E-24 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS11160 27edaedbb54b5bd14c0036b072188e0c 567 Gene3D G3DSA:3.50.50.60 277 320 1.6E-24 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS22905 0d021a5f7b092d1e77e6aa1faeaaac4e 613 Gene3D G3DSA:3.40.50.300 12 202 2.8E-53 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS22905 0d021a5f7b092d1e77e6aa1faeaaac4e 613 Gene3D G3DSA:1.10.10.10 345 520 5.6E-54 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS22905 0d021a5f7b092d1e77e6aa1faeaaac4e 613 SMART SM00956 411 517 1.2E-42 T 10-11-2016 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 A4G23_RS22905 0d021a5f7b092d1e77e6aa1faeaaac4e 613 SMART SM00490 250 331 7.6E-24 T 10-11-2016 IPR001650 Helicase, C-terminal A4G23_RS22905 0d021a5f7b092d1e77e6aa1faeaaac4e 613 SUPERFAMILY SSF52540 207 462 6.2E-60 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS22905 0d021a5f7b092d1e77e6aa1faeaaac4e 613 SUPERFAMILY SSF47819 538 612 1.18E-21 T 10-11-2016 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 A4G23_RS22905 0d021a5f7b092d1e77e6aa1faeaaac4e 613 Gene3D G3DSA:3.40.50.300 206 344 7.0E-48 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS22905 0d021a5f7b092d1e77e6aa1faeaaac4e 613 SUPERFAMILY SSF52540 10 196 2.13E-44 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS22905 0d021a5f7b092d1e77e6aa1faeaaac4e 613 Pfam PF09382 RQC domain 406 520 3.9E-33 T 10-11-2016 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 A4G23_RS22905 0d021a5f7b092d1e77e6aa1faeaaac4e 613 SMART SM00487 21 215 1.4E-27 T 10-11-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4G23_RS22905 0d021a5f7b092d1e77e6aa1faeaaac4e 613 Pfam PF16124 RecQ zinc-binding 343 404 1.5E-17 T 10-11-2016 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain A4G23_RS22905 0d021a5f7b092d1e77e6aa1faeaaac4e 613 SMART SM00341 540 611 1.2E-12 T 10-11-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 A4G23_RS22905 0d021a5f7b092d1e77e6aa1faeaaac4e 613 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 14 609 1.2E-232 T 10-11-2016 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 A4G23_RS22905 0d021a5f7b092d1e77e6aa1faeaaac4e 613 Pfam PF00271 Helicase conserved C-terminal domain 224 331 1.7E-14 T 10-11-2016 IPR001650 Helicase, C-terminal A4G23_RS22905 0d021a5f7b092d1e77e6aa1faeaaac4e 613 Pfam PF00570 HRDC domain 544 609 4.8E-22 T 10-11-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 A4G23_RS22905 0d021a5f7b092d1e77e6aa1faeaaac4e 613 Pfam PF00270 DEAD/DEAH box helicase 29 185 5.1E-17 T 10-11-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A4G23_RS22905 0d021a5f7b092d1e77e6aa1faeaaac4e 613 Gene3D G3DSA:1.10.150.80 546 610 1.5E-16 T 10-11-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 A4G23_RS22905 0d021a5f7b092d1e77e6aa1faeaaac4e 613 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 15 466 3.0E-150 T 10-11-2016 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 A4G23_RS13445 4c7ede22738506e7a16bd71f279504cd 687 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 57 198 7.1E-22 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS13445 4c7ede22738506e7a16bd71f279504cd 687 Gene3D G3DSA:3.30.565.10 30 239 4.4E-87 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS13445 4c7ede22738506e7a16bd71f279504cd 687 Gene3D G3DSA:3.40.50.670 452 669 3.6E-87 T 10-11-2016 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4G23_RS13445 4c7ede22738506e7a16bd71f279504cd 687 SMART SM00433 59 680 0.0 T 10-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4G23_RS13445 4c7ede22738506e7a16bd71f279504cd 687 SUPERFAMILY SSF54211 266 439 1.04E-54 T 10-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold A4G23_RS13445 4c7ede22738506e7a16bd71f279504cd 687 SUPERFAMILY SSF55874 30 236 8.25E-70 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS13445 4c7ede22738506e7a16bd71f279504cd 687 Pfam PF01751 Toprim domain 467 578 6.9E-17 T 10-11-2016 IPR006171 Toprim domain A4G23_RS13445 4c7ede22738506e7a16bd71f279504cd 687 SMART SM00387 55 199 1.9E-21 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS13445 4c7ede22738506e7a16bd71f279504cd 687 Gene3D G3DSA:3.30.230.10 265 440 8.9E-72 T 10-11-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A4G23_RS13445 4c7ede22738506e7a16bd71f279504cd 687 PRINTS PR00418 DNA topoisomerase II family signature 572 584 5.1E-66 T 10-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4G23_RS13445 4c7ede22738506e7a16bd71f279504cd 687 PRINTS PR00418 DNA topoisomerase II family signature 619 635 5.1E-66 T 10-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4G23_RS13445 4c7ede22738506e7a16bd71f279504cd 687 PRINTS PR00418 DNA topoisomerase II family signature 94 107 5.1E-66 T 10-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4G23_RS13445 4c7ede22738506e7a16bd71f279504cd 687 PRINTS PR00418 DNA topoisomerase II family signature 552 569 5.1E-66 T 10-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4G23_RS13445 4c7ede22738506e7a16bd71f279504cd 687 PRINTS PR00418 DNA topoisomerase II family signature 316 329 5.1E-66 T 10-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4G23_RS13445 4c7ede22738506e7a16bd71f279504cd 687 PRINTS PR00418 DNA topoisomerase II family signature 137 151 5.1E-66 T 10-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4G23_RS13445 4c7ede22738506e7a16bd71f279504cd 687 PRINTS PR00418 DNA topoisomerase II family signature 59 74 5.1E-66 T 10-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4G23_RS13445 4c7ede22738506e7a16bd71f279504cd 687 PRINTS PR00418 DNA topoisomerase II family signature 468 482 5.1E-66 T 10-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4G23_RS13445 4c7ede22738506e7a16bd71f279504cd 687 PRINTS PR00418 DNA topoisomerase II family signature 534 550 5.1E-66 T 10-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4G23_RS13445 4c7ede22738506e7a16bd71f279504cd 687 PRINTS PR01159 DNA gyrase subunit B signature 422 442 3.0E-75 T 10-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4G23_RS13445 4c7ede22738506e7a16bd71f279504cd 687 PRINTS PR01159 DNA gyrase subunit B signature 518 527 3.0E-75 T 10-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4G23_RS13445 4c7ede22738506e7a16bd71f279504cd 687 PRINTS PR01159 DNA gyrase subunit B signature 204 219 3.0E-75 T 10-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4G23_RS13445 4c7ede22738506e7a16bd71f279504cd 687 PRINTS PR01159 DNA gyrase subunit B signature 265 287 3.0E-75 T 10-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4G23_RS13445 4c7ede22738506e7a16bd71f279504cd 687 PRINTS PR01159 DNA gyrase subunit B signature 640 652 3.0E-75 T 10-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4G23_RS13445 4c7ede22738506e7a16bd71f279504cd 687 PRINTS PR01159 DNA gyrase subunit B signature 408 422 3.0E-75 T 10-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4G23_RS13445 4c7ede22738506e7a16bd71f279504cd 687 PRINTS PR01159 DNA gyrase subunit B signature 219 232 3.0E-75 T 10-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4G23_RS13445 4c7ede22738506e7a16bd71f279504cd 687 PRINTS PR01159 DNA gyrase subunit B signature 656 672 3.0E-75 T 10-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4G23_RS13445 4c7ede22738506e7a16bd71f279504cd 687 PRINTS PR01159 DNA gyrase subunit B signature 30 40 3.0E-75 T 10-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4G23_RS13445 4c7ede22738506e7a16bd71f279504cd 687 PRINTS PR01159 DNA gyrase subunit B signature 290 308 3.0E-75 T 10-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4G23_RS13445 4c7ede22738506e7a16bd71f279504cd 687 PRINTS PR01159 DNA gyrase subunit B signature 360 376 3.0E-75 T 10-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4G23_RS13445 4c7ede22738506e7a16bd71f279504cd 687 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 27 687 88.961 T 10-11-2016 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A4G23_RS13445 4c7ede22738506e7a16bd71f279504cd 687 SUPERFAMILY SSF56719 442 682 6.02E-82 T 10-11-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 A4G23_RS13445 4c7ede22738506e7a16bd71f279504cd 687 Pfam PF00204 DNA gyrase B 266 438 1.9E-62 T 10-11-2016 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4G23_RS13445 4c7ede22738506e7a16bd71f279504cd 687 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 618 676 1.9E-24 T 10-11-2016 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4G23_RS13445 4c7ede22738506e7a16bd71f279504cd 687 ProSitePatterns PS00177 DNA topoisomerase II signature. 470 478 - T 10-11-2016 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4G23_RS13445 4c7ede22738506e7a16bd71f279504cd 687 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 30 687 1.5E-284 T 10-11-2016 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A4G23_RS08105 0d7a050b58f4672a6ec782785856035d 371 ProSitePatterns PS00902 Glutamate 5-kinase signature. 208 225 - T 10-11-2016 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A4G23_RS08105 0d7a050b58f4672a6ec782785856035d 371 Gene3D G3DSA:2.30.130.10 272 364 7.4E-25 T 10-11-2016 IPR015947 PUA-like domain A4G23_RS08105 0d7a050b58f4672a6ec782785856035d 371 Gene3D G3DSA:3.40.1160.10 5 254 6.3E-57 T 10-11-2016 IPR001048 Aspartate/glutamate/uridylate kinase A4G23_RS08105 0d7a050b58f4672a6ec782785856035d 371 Pfam PF00696 Amino acid kinase family 6 236 9.1E-43 T 10-11-2016 IPR001048 Aspartate/glutamate/uridylate kinase A4G23_RS08105 0d7a050b58f4672a6ec782785856035d 371 SUPERFAMILY SSF53633 5 254 1.7E-64 T 10-11-2016 IPR001048 Aspartate/glutamate/uridylate kinase A4G23_RS08105 0d7a050b58f4672a6ec782785856035d 371 PIRSF PIRSF000729 1 367 6.1E-125 T 10-11-2016 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 A4G23_RS08105 0d7a050b58f4672a6ec782785856035d 371 Hamap MF_00456 Glutamate 5-kinase [proB]. 5 256 36.568 T 10-11-2016 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A4G23_RS08105 0d7a050b58f4672a6ec782785856035d 371 SUPERFAMILY SSF88697 275 365 1.55E-21 T 10-11-2016 IPR015947 PUA-like domain A4G23_RS08105 0d7a050b58f4672a6ec782785856035d 371 SMART SM00359 275 354 3.0E-18 T 10-11-2016 IPR002478 PUA domain GO:0003723 A4G23_RS08105 0d7a050b58f4672a6ec782785856035d 371 PRINTS PR00474 Glutamate 5-kinase family signature 149 176 1.4E-54 T 10-11-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 A4G23_RS08105 0d7a050b58f4672a6ec782785856035d 371 PRINTS PR00474 Glutamate 5-kinase family signature 117 138 1.4E-54 T 10-11-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 A4G23_RS08105 0d7a050b58f4672a6ec782785856035d 371 PRINTS PR00474 Glutamate 5-kinase family signature 77 105 1.4E-54 T 10-11-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 A4G23_RS08105 0d7a050b58f4672a6ec782785856035d 371 PRINTS PR00474 Glutamate 5-kinase family signature 43 57 1.4E-54 T 10-11-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 A4G23_RS08105 0d7a050b58f4672a6ec782785856035d 371 PRINTS PR00474 Glutamate 5-kinase family signature 210 230 1.4E-54 T 10-11-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 A4G23_RS08105 0d7a050b58f4672a6ec782785856035d 371 Pfam PF01472 PUA domain 275 349 5.1E-18 T 10-11-2016 IPR002478 PUA domain GO:0003723 A4G23_RS08105 0d7a050b58f4672a6ec782785856035d 371 TIGRFAM TIGR01027 proB: glutamate 5-kinase 5 364 4.3E-129 T 10-11-2016 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A4G23_RS25970 a234920e2209cdab19958057decef84c 349 Pfam PF10935 Protein of unknown function (DUF2637) 195 306 2.2E-5 T 10-11-2016 IPR021235 Protein of unknown function DUF2637 A4G23_RS00615 f4965c4abf2cfaaece95b87e5499f517 620 Pfam PF05547 Immune inhibitor A peptidase M6 443 614 2.0E-7 T 10-11-2016 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 A4G23_RS00615 f4965c4abf2cfaaece95b87e5499f517 620 SUPERFAMILY SSF56601 102 435 9.95E-81 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS00615 f4965c4abf2cfaaece95b87e5499f517 620 Pfam PF00144 Beta-lactamase 103 437 3.1E-72 T 10-11-2016 IPR001466 Beta-lactamase-related A4G23_RS00615 f4965c4abf2cfaaece95b87e5499f517 620 Gene3D G3DSA:3.40.710.10 104 434 1.9E-79 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS09545 19e4aa6609c17c7b0a39ba3202533e9c 265 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 156 248 8.3E-6 T 10-11-2016 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 A4G23_RS09545 19e4aa6609c17c7b0a39ba3202533e9c 265 SUPERFAMILY SSF54211 110 253 4.55E-18 T 10-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold A4G23_RS09545 19e4aa6609c17c7b0a39ba3202533e9c 265 Gene3D G3DSA:3.30.230.10 110 252 8.6E-22 T 10-11-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A4G23_RS18760 031a28896ceeffa1eb87cebd05a035de 468 Gene3D G3DSA:3.30.70.360 207 369 2.9E-57 T 10-11-2016 IPR011650 Peptidase M20, dimerisation domain A4G23_RS18760 031a28896ceeffa1eb87cebd05a035de 468 Pfam PF07687 Peptidase dimerisation domain 204 363 1.5E-23 T 10-11-2016 IPR011650 Peptidase M20, dimerisation domain A4G23_RS18760 031a28896ceeffa1eb87cebd05a035de 468 SUPERFAMILY SSF53187 11 207 1.11E-61 T 10-11-2016 A4G23_RS18760 031a28896ceeffa1eb87cebd05a035de 468 SUPERFAMILY SSF53187 378 464 1.11E-61 T 10-11-2016 A4G23_RS18760 031a28896ceeffa1eb87cebd05a035de 468 Pfam PF01546 Peptidase family M20/M25/M40 91 459 8.5E-33 T 10-11-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A4G23_RS18760 031a28896ceeffa1eb87cebd05a035de 468 Gene3D G3DSA:3.40.630.10 377 463 2.6E-63 T 10-11-2016 A4G23_RS18760 031a28896ceeffa1eb87cebd05a035de 468 Gene3D G3DSA:3.40.630.10 11 201 2.6E-63 T 10-11-2016 A4G23_RS05050 33efe7b1cb6c99d44c8e85651b74a2f2 142 SUPERFAMILY SSF141322 74 141 1.26E-7 T 10-11-2016 A4G23_RS05050 33efe7b1cb6c99d44c8e85651b74a2f2 142 Gene3D G3DSA:2.40.50.140 83 141 6.6E-24 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS05050 33efe7b1cb6c99d44c8e85651b74a2f2 142 Pfam PF01957 NfeD-like C-terminal, partner-binding 9 141 2.5E-16 T 10-11-2016 IPR002810 NfeD-like, C-terminal domain A4G23_RS17790 981824463694f3d37df10b8c9e88adc6 274 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 89 130 - T 10-11-2016 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 A4G23_RS17790 981824463694f3d37df10b8c9e88adc6 274 Gene3D G3DSA:3.40.50.1580 15 273 5.1E-89 T 10-11-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A4G23_RS17790 981824463694f3d37df10b8c9e88adc6 274 Pfam PF01048 Phosphorylase superfamily 36 271 1.8E-39 T 10-11-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A4G23_RS17790 981824463694f3d37df10b8c9e88adc6 274 PIRSF PIRSF000477 8 274 3.4E-87 T 10-11-2016 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-74217|Reactome: R-HSA-74259 A4G23_RS17790 981824463694f3d37df10b8c9e88adc6 274 TIGRFAM TIGR01698 PUNP: purine nucleotide phosphorylase 36 270 2.0E-99 T 10-11-2016 IPR011269 Putative purine nucleotide phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 A4G23_RS17790 981824463694f3d37df10b8c9e88adc6 274 SUPERFAMILY SSF53167 19 274 2.5E-78 T 10-11-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A4G23_RS17790 981824463694f3d37df10b8c9e88adc6 274 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 36 271 2.2E-74 T 10-11-2016 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-74217|Reactome: R-HSA-74259 A4G23_RS05710 ba061b22c04d446a864ddfb531a72772 964 Hamap MF_00205 UvrABC system protein A [uvrA]. 2 944 22.784 T 10-11-2016 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 A4G23_RS05710 ba061b22c04d446a864ddfb531a72772 964 Gene3D G3DSA:3.30.1490.20 201 242 5.1E-24 T 10-11-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A4G23_RS05710 ba061b22c04d446a864ddfb531a72772 964 Gene3D G3DSA:3.30.1490.20 131 154 5.1E-24 T 10-11-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A4G23_RS05710 ba061b22c04d446a864ddfb531a72772 964 Gene3D G3DSA:1.20.1580.10 698 824 1.0E-55 T 10-11-2016 A4G23_RS05710 ba061b22c04d446a864ddfb531a72772 964 Gene3D G3DSA:1.20.1580.10 92 130 3.3E-56 T 10-11-2016 A4G23_RS05710 ba061b22c04d446a864ddfb531a72772 964 Gene3D G3DSA:1.20.1580.10 412 482 3.3E-56 T 10-11-2016 A4G23_RS05710 ba061b22c04d446a864ddfb531a72772 964 Gene3D G3DSA:1.20.1580.10 255 288 3.3E-56 T 10-11-2016 A4G23_RS05710 ba061b22c04d446a864ddfb531a72772 964 Gene3D G3DSA:3.40.50.300 616 684 6.9E-58 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05710 ba061b22c04d446a864ddfb531a72772 964 Gene3D G3DSA:3.40.50.300 6 90 6.1E-56 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05710 ba061b22c04d446a864ddfb531a72772 964 Gene3D G3DSA:3.40.50.300 483 601 6.1E-56 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05710 ba061b22c04d446a864ddfb531a72772 964 Gene3D G3DSA:3.40.50.300 825 942 6.9E-58 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05710 ba061b22c04d446a864ddfb531a72772 964 ProSitePatterns PS00211 ABC transporters family signature. 834 848 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS05710 ba061b22c04d446a864ddfb531a72772 964 Gene3D G3DSA:1.10.8.280 290 411 4.2E-37 T 10-11-2016 A4G23_RS05710 ba061b22c04d446a864ddfb531a72772 964 SUPERFAMILY SSF52540 619 913 6.91E-52 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05710 ba061b22c04d446a864ddfb531a72772 964 ProSitePatterns PS00211 ABC transporters family signature. 492 506 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS05710 ba061b22c04d446a864ddfb531a72772 964 SUPERFAMILY SSF52540 435 574 5.65E-45 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05710 ba061b22c04d446a864ddfb531a72772 964 SUPERFAMILY SSF52540 10 205 5.65E-45 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05710 ba061b22c04d446a864ddfb531a72772 964 Pfam PF00005 ABC transporter 628 864 3.0E-10 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS05710 ba061b22c04d446a864ddfb531a72772 964 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 5 929 0.0 T 10-11-2016 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 A4G23_RS13810 111999b367b00a9d97528ec52a1f5295 232 Pfam PF02630 SCO1/SenC 71 172 9.9E-22 T 10-11-2016 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS13810 111999b367b00a9d97528ec52a1f5295 232 SUPERFAMILY SSF52833 68 228 8.47E-36 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS13810 111999b367b00a9d97528ec52a1f5295 232 Gene3D G3DSA:3.40.30.10 25 229 1.3E-42 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS15835 053fccdb75805620622b9506d008e134 204 Pfam PF00578 AhpC/TSA family 63 178 1.1E-19 T 10-11-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A4G23_RS15835 053fccdb75805620622b9506d008e134 204 Gene3D G3DSA:3.40.30.10 10 200 2.9E-41 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS15835 053fccdb75805620622b9506d008e134 204 SUPERFAMILY SSF52833 62 198 6.8E-29 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS08690 198a17c2692a192ef052001b1cf4439a 385 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 103 121 7.0E-14 T 10-11-2016 A4G23_RS08690 198a17c2692a192ef052001b1cf4439a 385 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 150 168 7.0E-14 T 10-11-2016 A4G23_RS08690 198a17c2692a192ef052001b1cf4439a 385 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 7.0E-14 T 10-11-2016 A4G23_RS08690 198a17c2692a192ef052001b1cf4439a 385 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 259 281 7.0E-14 T 10-11-2016 A4G23_RS08690 198a17c2692a192ef052001b1cf4439a 385 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 304 3.6E-35 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS08690 198a17c2692a192ef052001b1cf4439a 385 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 104 112 3.1E-7 T 10-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4G23_RS08690 198a17c2692a192ef052001b1cf4439a 385 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 5 27 3.1E-7 T 10-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4G23_RS08690 198a17c2692a192ef052001b1cf4439a 385 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 146 170 3.1E-7 T 10-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4G23_RS08690 198a17c2692a192ef052001b1cf4439a 385 Gene3D G3DSA:3.50.50.60 164 311 1.9E-19 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS08690 198a17c2692a192ef052001b1cf4439a 385 SUPERFAMILY SSF51905 4 329 2.53E-27 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS08690 198a17c2692a192ef052001b1cf4439a 385 Gene3D G3DSA:3.50.50.60 3 163 2.8E-24 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS20860 5fb3a5bedfc80376949e9497d3346418 566 SUPERFAMILY SSF55681 407 478 3.19E-87 T 10-11-2016 A4G23_RS20860 5fb3a5bedfc80376949e9497d3346418 566 SUPERFAMILY SSF55681 14 241 3.19E-87 T 10-11-2016 A4G23_RS20860 5fb3a5bedfc80376949e9497d3346418 566 Pfam PF04073 Aminoacyl-tRNA editing domain 261 375 8.8E-28 T 10-11-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 A4G23_RS20860 5fb3a5bedfc80376949e9497d3346418 566 Gene3D G3DSA:3.30.930.10 389 469 3.3E-94 T 10-11-2016 A4G23_RS20860 5fb3a5bedfc80376949e9497d3346418 566 Gene3D G3DSA:3.30.930.10 15 238 3.3E-94 T 10-11-2016 A4G23_RS20860 5fb3a5bedfc80376949e9497d3346418 566 SUPERFAMILY SSF52954 461 564 6.34E-24 T 10-11-2016 IPR004154 Anticodon-binding A4G23_RS20860 5fb3a5bedfc80376949e9497d3346418 566 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 6 563 2.7E-172 T 10-11-2016 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A4G23_RS20860 5fb3a5bedfc80376949e9497d3346418 566 Gene3D G3DSA:3.40.50.800 470 565 6.1E-22 T 10-11-2016 IPR004154 Anticodon-binding A4G23_RS20860 5fb3a5bedfc80376949e9497d3346418 566 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 98 458 2.4E-41 T 10-11-2016 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4G23_RS20860 5fb3a5bedfc80376949e9497d3346418 566 Hamap MF_01569 Proline--tRNA ligase [proS]. 5 566 36.333 T 10-11-2016 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 A4G23_RS20860 5fb3a5bedfc80376949e9497d3346418 566 Gene3D G3DSA:3.90.960.10 260 371 1.9E-20 T 10-11-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 A4G23_RS20860 5fb3a5bedfc80376949e9497d3346418 566 SUPERFAMILY SSF55826 222 388 6.28E-22 T 10-11-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 A4G23_RS20860 5fb3a5bedfc80376949e9497d3346418 566 PRINTS PR01046 Prolyl-tRNA synthetase signature 108 119 1.5E-15 T 10-11-2016 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A4G23_RS20860 5fb3a5bedfc80376949e9497d3346418 566 PRINTS PR01046 Prolyl-tRNA synthetase signature 148 159 1.5E-15 T 10-11-2016 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A4G23_RS20860 5fb3a5bedfc80376949e9497d3346418 566 PRINTS PR01046 Prolyl-tRNA synthetase signature 72 90 1.5E-15 T 10-11-2016 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A4G23_RS20860 5fb3a5bedfc80376949e9497d3346418 566 PRINTS PR01046 Prolyl-tRNA synthetase signature 138 146 1.5E-15 T 10-11-2016 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A4G23_RS20860 5fb3a5bedfc80376949e9497d3346418 566 Pfam PF03129 Anticodon binding domain 476 564 6.5E-16 T 10-11-2016 IPR004154 Anticodon-binding A4G23_RS26625 cf98f3c371bf70c744d7eccc84ed130a 230 SUPERFAMILY SSF46689 3 79 3.84E-18 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS26625 cf98f3c371bf70c744d7eccc84ed130a 230 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 1.0E-7 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS26625 cf98f3c371bf70c744d7eccc84ed130a 230 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 1.0E-7 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS26625 cf98f3c371bf70c744d7eccc84ed130a 230 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 61 2.8E-13 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS26625 cf98f3c371bf70c744d7eccc84ed130a 230 Gene3D G3DSA:1.10.357.10 8 185 2.4E-27 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS09140 16a030033fca7a38210d4da7415e1bb5 153 SUPERFAMILY SSF54427 3 144 3.07E-68 T 10-11-2016 IPR032710 NTF2-like domain A4G23_RS09140 16a030033fca7a38210d4da7415e1bb5 153 Pfam PF07080 Protein of unknown function (DUF1348) 5 139 8.9E-66 T 10-11-2016 IPR009783 Protein of unknown function DUF1348 A4G23_RS09140 16a030033fca7a38210d4da7415e1bb5 153 Gene3D G3DSA:3.10.450.50 13 143 1.8E-64 T 10-11-2016 IPR032710 NTF2-like domain A4G23_RS06885 1cc9a8a6baab58155d2940ebda23e226 995 SUPERFAMILY SSF81301 553 835 1.31E-57 T 10-11-2016 A4G23_RS06885 1cc9a8a6baab58155d2940ebda23e226 995 SUPERFAMILY SSF81301 72 322 4.25E-67 T 10-11-2016 A4G23_RS06885 1cc9a8a6baab58155d2940ebda23e226 995 Gene3D G3DSA:3.30.460.10 677 835 5.1E-50 T 10-11-2016 A4G23_RS06885 1cc9a8a6baab58155d2940ebda23e226 995 Gene3D G3DSA:3.30.460.10 163 323 4.2E-55 T 10-11-2016 A4G23_RS06885 1cc9a8a6baab58155d2940ebda23e226 995 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 88 313 1.4E-48 T 10-11-2016 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 A4G23_RS06885 1cc9a8a6baab58155d2940ebda23e226 995 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 581 826 1.0E-40 T 10-11-2016 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 A4G23_RS06885 1cc9a8a6baab58155d2940ebda23e226 995 SUPERFAMILY SSF81593 840 993 5.81E-37 T 10-11-2016 A4G23_RS06885 1cc9a8a6baab58155d2940ebda23e226 995 Pfam PF08335 GlnD PII-uridylyltransferase 336 476 6.2E-36 T 10-11-2016 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 A4G23_RS06885 1cc9a8a6baab58155d2940ebda23e226 995 Pfam PF08335 GlnD PII-uridylyltransferase 850 992 3.9E-20 T 10-11-2016 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 A4G23_RS06885 1cc9a8a6baab58155d2940ebda23e226 995 Hamap MF_00802 Glutamate-ammonia-ligase adenylyltransferase [glnE]. 84 983 17.038 T 10-11-2016 IPR023057 Glutamate-ammonia-ligase adenylyltransferase GO:0008882 A4G23_RS06885 1cc9a8a6baab58155d2940ebda23e226 995 SUPERFAMILY SSF81593 329 477 1.41E-38 T 10-11-2016 A4G23_RS25990 f07e23b1ff52856e49a128c7e6ab93f4 131 Gene3D G3DSA:3.40.630.30 19 122 2.6E-12 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS25990 f07e23b1ff52856e49a128c7e6ab93f4 131 Pfam PF00583 Acetyltransferase (GNAT) family 48 122 1.5E-8 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS25990 f07e23b1ff52856e49a128c7e6ab93f4 131 SUPERFAMILY SSF55729 28 122 2.16E-12 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS08890 d582f009bfd77e7f1099f759b41c658f 1185 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 7 231 1.9E-15 T 10-11-2016 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 A4G23_RS08890 d582f009bfd77e7f1099f759b41c658f 1185 SUPERFAMILY SSF52540 465 523 9.14E-18 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS08890 d582f009bfd77e7f1099f759b41c658f 1185 SUPERFAMILY SSF52540 285 423 9.14E-18 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS08890 d582f009bfd77e7f1099f759b41c658f 1185 Pfam PF04851 Type III restriction enzyme, res subunit 306 510 1.2E-15 T 10-11-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 A4G23_RS08890 d582f009bfd77e7f1099f759b41c658f 1185 SMART SM00487 299 547 5.2E-6 T 10-11-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4G23_RS08890 d582f009bfd77e7f1099f759b41c658f 1185 Gene3D G3DSA:3.40.50.300 475 510 1.5E-14 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS08890 d582f009bfd77e7f1099f759b41c658f 1185 Gene3D G3DSA:3.40.50.300 305 432 1.5E-14 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS21910 5042383bf096b2b91ff0116f4ec3e148 126 Pfam PF01022 Bacterial regulatory protein, arsR family 17 59 2.4E-12 T 10-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4G23_RS21910 5042383bf096b2b91ff0116f4ec3e148 126 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 29 40 9.0E-5 T 10-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 A4G23_RS21910 5042383bf096b2b91ff0116f4ec3e148 126 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 40 59 9.0E-5 T 10-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 A4G23_RS21910 5042383bf096b2b91ff0116f4ec3e148 126 SMART SM00418 8 95 1.6E-6 T 10-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4G23_RS21910 5042383bf096b2b91ff0116f4ec3e148 126 SUPERFAMILY SSF46785 4 84 3.45E-20 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS21910 5042383bf096b2b91ff0116f4ec3e148 126 Gene3D G3DSA:1.10.10.10 2 78 3.1E-17 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS21755 151bbbfa7ad712e24a86bcb752dee898 499 Pfam PF00270 DEAD/DEAH box helicase 93 260 1.0E-43 T 10-11-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A4G23_RS21755 151bbbfa7ad712e24a86bcb752dee898 499 SUPERFAMILY SSF52540 141 419 4.61E-63 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS21755 151bbbfa7ad712e24a86bcb752dee898 499 Pfam PF00271 Helicase conserved C-terminal domain 305 403 2.0E-24 T 10-11-2016 IPR001650 Helicase, C-terminal A4G23_RS21755 151bbbfa7ad712e24a86bcb752dee898 499 SMART SM00487 88 288 3.1E-48 T 10-11-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4G23_RS21755 151bbbfa7ad712e24a86bcb752dee898 499 Gene3D G3DSA:3.40.50.300 278 429 2.1E-40 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS21755 151bbbfa7ad712e24a86bcb752dee898 499 Gene3D G3DSA:3.40.50.300 67 277 8.5E-69 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS21755 151bbbfa7ad712e24a86bcb752dee898 499 SMART SM00490 322 403 2.1E-28 T 10-11-2016 IPR001650 Helicase, C-terminal A4G23_RS08010 839b9f05a1f5573b772442c1140c3d10 490 SUPERFAMILY SSF56349 184 257 1.32E-12 T 10-11-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A4G23_RS08010 839b9f05a1f5573b772442c1140c3d10 490 SUPERFAMILY SSF56349 318 439 1.32E-12 T 10-11-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A4G23_RS08010 839b9f05a1f5573b772442c1140c3d10 490 SUPERFAMILY SSF56349 28 210 3.18E-6 T 10-11-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A4G23_RS08010 839b9f05a1f5573b772442c1140c3d10 490 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 43 116 1.9E-6 T 10-11-2016 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 A4G23_RS08010 839b9f05a1f5573b772442c1140c3d10 490 Gene3D G3DSA:1.10.443.10 184 270 5.7E-20 T 10-11-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 A4G23_RS08010 839b9f05a1f5573b772442c1140c3d10 490 Gene3D G3DSA:1.10.443.10 330 437 5.7E-20 T 10-11-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 A4G23_RS08010 839b9f05a1f5573b772442c1140c3d10 490 Gene3D G3DSA:1.10.150.130 42 125 1.7E-8 T 10-11-2016 IPR023109 Integrase/recombinase, N-terminal A4G23_RS03375 bdd4cb72048ba3dc406dac0cdabcc56c 200 SUPERFAMILY SSF63380 2 88 2.72E-25 T 10-11-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 A4G23_RS03375 bdd4cb72048ba3dc406dac0cdabcc56c 200 Pfam PF00677 Lumazine binding domain 3 85 3.0E-23 T 10-11-2016 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4G23_RS03375 bdd4cb72048ba3dc406dac0cdabcc56c 200 Pfam PF00677 Lumazine binding domain 99 183 7.4E-25 T 10-11-2016 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4G23_RS03375 bdd4cb72048ba3dc406dac0cdabcc56c 200 SUPERFAMILY SSF63380 92 194 4.0E-34 T 10-11-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 A4G23_RS03375 bdd4cb72048ba3dc406dac0cdabcc56c 200 PIRSF PIRSF000498 1 200 1.7E-70 T 10-11-2016 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4G23_RS03375 bdd4cb72048ba3dc406dac0cdabcc56c 200 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 2 193 2.2E-64 T 10-11-2016 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4G23_RS03375 bdd4cb72048ba3dc406dac0cdabcc56c 200 Gene3D G3DSA:2.40.30.20 104 195 3.7E-33 T 10-11-2016 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 A4G23_RS03375 bdd4cb72048ba3dc406dac0cdabcc56c 200 Gene3D G3DSA:2.40.30.20 5 103 1.6E-33 T 10-11-2016 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 A4G23_RS06210 9a208bf4fc67665cbdeaa3649fc4f73a 98 Pfam PF02325 YGGT family 10 90 1.9E-11 T 10-11-2016 IPR003425 CCB3/YggT GO:0016020 A4G23_RS06390 bfa936ce8122c7fc9ca3f00ac492703b 159 TIGRFAM TIGR00754 bfr: bacterioferritin 1 156 4.7E-63 T 10-11-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 A4G23_RS06390 bfa936ce8122c7fc9ca3f00ac492703b 159 Gene3D G3DSA:1.20.1260.10 1 156 1.1E-53 T 10-11-2016 IPR012347 Ferritin-related A4G23_RS06390 bfa936ce8122c7fc9ca3f00ac492703b 159 PIRSF PIRSF002560 1 157 6.7E-65 T 10-11-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 A4G23_RS06390 bfa936ce8122c7fc9ca3f00ac492703b 159 SUPERFAMILY SSF47240 1 155 2.71E-45 T 10-11-2016 IPR009078 Ferritin-like superfamily A4G23_RS06390 bfa936ce8122c7fc9ca3f00ac492703b 159 ProSitePatterns PS00549 Bacterioferritin signature. 1 19 - T 10-11-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 A4G23_RS06390 bfa936ce8122c7fc9ca3f00ac492703b 159 Pfam PF00210 Ferritin-like domain 8 143 1.1E-32 T 10-11-2016 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 A4G23_RS06390 bfa936ce8122c7fc9ca3f00ac492703b 159 PRINTS PR00601 Bacterioferritin signature 128 149 5.1E-55 T 10-11-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 A4G23_RS06390 bfa936ce8122c7fc9ca3f00ac492703b 159 PRINTS PR00601 Bacterioferritin signature 3 22 5.1E-55 T 10-11-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 A4G23_RS06390 bfa936ce8122c7fc9ca3f00ac492703b 159 PRINTS PR00601 Bacterioferritin signature 86 106 5.1E-55 T 10-11-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 A4G23_RS06390 bfa936ce8122c7fc9ca3f00ac492703b 159 PRINTS PR00601 Bacterioferritin signature 23 43 5.1E-55 T 10-11-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 A4G23_RS06390 bfa936ce8122c7fc9ca3f00ac492703b 159 PRINTS PR00601 Bacterioferritin signature 107 127 5.1E-55 T 10-11-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 A4G23_RS06390 bfa936ce8122c7fc9ca3f00ac492703b 159 PRINTS PR00601 Bacterioferritin signature 65 85 5.1E-55 T 10-11-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 A4G23_RS06390 bfa936ce8122c7fc9ca3f00ac492703b 159 PRINTS PR00601 Bacterioferritin signature 44 64 5.1E-55 T 10-11-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 A4G23_RS03895 ffdd769bb79c30cb8d7d0a0750dff8d1 419 Gene3D G3DSA:3.30.200.20 9 93 1.0E-16 T 10-11-2016 A4G23_RS03895 ffdd769bb79c30cb8d7d0a0750dff8d1 419 SMART SM00220 17 269 2.8E-48 T 10-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4G23_RS03895 ffdd769bb79c30cb8d7d0a0750dff8d1 419 Gene3D G3DSA:1.10.510.10 99 334 3.5E-39 T 10-11-2016 A4G23_RS03895 ffdd769bb79c30cb8d7d0a0750dff8d1 419 SUPERFAMILY SSF56112 13 261 2.02E-62 T 10-11-2016 IPR011009 Protein kinase-like domain A4G23_RS03895 ffdd769bb79c30cb8d7d0a0750dff8d1 419 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 23 45 - T 10-11-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 A4G23_RS03895 ffdd769bb79c30cb8d7d0a0750dff8d1 419 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 135 147 - T 10-11-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 A4G23_RS03895 ffdd769bb79c30cb8d7d0a0750dff8d1 419 Pfam PF00069 Protein kinase domain 18 261 1.1E-39 T 10-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4G23_RS12360 6339e7fb7b52afb252ddc04b818dc150 254 Pfam PF00440 Bacterial regulatory proteins, tetR family 39 82 4.1E-10 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS12360 6339e7fb7b52afb252ddc04b818dc150 254 Gene3D G3DSA:1.10.357.10 25 252 1.2E-57 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS12360 6339e7fb7b52afb252ddc04b818dc150 254 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 97 247 1.0E-14 T 10-11-2016 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 A4G23_RS12360 6339e7fb7b52afb252ddc04b818dc150 254 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 52 7.9E-5 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS12360 6339e7fb7b52afb252ddc04b818dc150 254 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 60 83 7.9E-5 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS12360 6339e7fb7b52afb252ddc04b818dc150 254 SUPERFAMILY SSF46689 29 89 6.48E-14 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS12360 6339e7fb7b52afb252ddc04b818dc150 254 SUPERFAMILY SSF48498 102 250 1.89E-22 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS12500 0762bcaef19ab160f3ba09540319ee25 89 SMART SM00345 19 71 3.4E-7 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS12500 0762bcaef19ab160f3ba09540319ee25 89 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 71 6.9E-11 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS12500 0762bcaef19ab160f3ba09540319ee25 89 SUPERFAMILY SSF46785 19 73 2.16E-13 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS12500 0762bcaef19ab160f3ba09540319ee25 89 Gene3D G3DSA:1.10.10.10 19 73 4.2E-16 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS24645 7bd2da5c8b7bf8a6c67828ec168f69b3 151 SUPERFAMILY SSF55874 46 140 3.33E-11 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS24645 7bd2da5c8b7bf8a6c67828ec168f69b3 151 Pfam PF13581 Histidine kinase-like ATPase domain 26 126 1.9E-13 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS24645 7bd2da5c8b7bf8a6c67828ec168f69b3 151 Gene3D G3DSA:3.30.565.10 31 121 1.5E-8 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS14555 4f465389266d8591b3a481bd499b5dca 219 Gene3D G3DSA:1.10.10.10 126 217 2.4E-31 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS14555 4f465389266d8591b3a481bd499b5dca 219 ProSitePatterns PS00622 LuxR-type HTH domain signature. 170 197 - T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS14555 4f465389266d8591b3a481bd499b5dca 219 Pfam PF00072 Response regulator receiver domain 5 114 2.9E-26 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS14555 4f465389266d8591b3a481bd499b5dca 219 Gene3D G3DSA:3.40.50.2300 2 125 3.2E-39 T 10-11-2016 A4G23_RS14555 4f465389266d8591b3a481bd499b5dca 219 SMART SM00448 3 116 1.9E-31 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS14555 4f465389266d8591b3a481bd499b5dca 219 Pfam PF00196 Bacterial regulatory proteins, luxR family 156 210 1.0E-17 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS14555 4f465389266d8591b3a481bd499b5dca 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 4.4E-14 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS14555 4f465389266d8591b3a481bd499b5dca 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 4.4E-14 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS14555 4f465389266d8591b3a481bd499b5dca 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 4.4E-14 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS14555 4f465389266d8591b3a481bd499b5dca 219 SUPERFAMILY SSF46894 141 216 9.52E-22 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS14555 4f465389266d8591b3a481bd499b5dca 219 SMART SM00421 153 210 2.8E-25 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS14555 4f465389266d8591b3a481bd499b5dca 219 SUPERFAMILY SSF52172 3 134 1.85E-34 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS00740 6c950eb239b59d567b1fec9263a8da3c 300 SUPERFAMILY SSF51735 57 297 9.21E-83 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS00740 6c950eb239b59d567b1fec9263a8da3c 300 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 188 196 1.5E-10 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS00740 6c950eb239b59d567b1fec9263a8da3c 300 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 208 227 1.5E-10 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS00740 6c950eb239b59d567b1fec9263a8da3c 300 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 146 1.5E-10 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS00740 6c950eb239b59d567b1fec9263a8da3c 300 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 227 7.6E-39 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS00740 6c950eb239b59d567b1fec9263a8da3c 300 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 261 281 7.6E-39 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS00740 6c950eb239b59d567b1fec9263a8da3c 300 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 59 76 7.6E-39 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS00740 6c950eb239b59d567b1fec9263a8da3c 300 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 198 7.6E-39 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS00740 6c950eb239b59d567b1fec9263a8da3c 300 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 146 7.6E-39 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS00740 6c950eb239b59d567b1fec9263a8da3c 300 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 229 246 7.6E-39 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS00740 6c950eb239b59d567b1fec9263a8da3c 300 Gene3D G3DSA:3.40.50.720 54 296 1.0E-85 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS00740 6c950eb239b59d567b1fec9263a8da3c 300 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 58 245 0.0024 T 10-11-2016 A4G23_RS00740 6c950eb239b59d567b1fec9263a8da3c 300 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 67 296 3.0E-62 T 10-11-2016 A4G23_RS00740 6c950eb239b59d567b1fec9263a8da3c 300 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 195 223 - T 10-11-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4G23_RS11575 c22b9ea94a41c69ae714c338e8ccb8d0 314 Pfam PF00892 EamA-like transporter family 172 302 1.0E-16 T 10-11-2016 IPR000620 EamA domain GO:0016020|GO:0016021 A4G23_RS11575 c22b9ea94a41c69ae714c338e8ccb8d0 314 SUPERFAMILY SSF103481 71 164 1.7E-6 T 10-11-2016 A4G23_RS11575 c22b9ea94a41c69ae714c338e8ccb8d0 314 SUPERFAMILY SSF103481 209 307 9.16E-11 T 10-11-2016 A4G23_RS06610 b5ff49755007fe0fd6393b755b686efd 1057 Gene3D G3DSA:3.30.2090.10 184 267 7.8E-11 T 10-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A4G23_RS06610 b5ff49755007fe0fd6393b755b686efd 1057 SUPERFAMILY SSF82714 184 267 3.4E-11 T 10-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A4G23_RS06610 b5ff49755007fe0fd6393b755b686efd 1057 Gene3D G3DSA:1.10.3850.10 276 494 4.9E-57 T 10-11-2016 A4G23_RS06610 b5ff49755007fe0fd6393b755b686efd 1057 Gene3D G3DSA:1.10.3850.10 796 1010 9.6E-58 T 10-11-2016 A4G23_RS06610 b5ff49755007fe0fd6393b755b686efd 1057 SUPERFAMILY SSF82693 565 653 1.5E-8 T 10-11-2016 A4G23_RS06610 b5ff49755007fe0fd6393b755b686efd 1057 Pfam PF00873 AcrB/AcrD/AcrF family 5 1009 5.1E-214 T 10-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A4G23_RS06610 b5ff49755007fe0fd6393b755b686efd 1057 SUPERFAMILY SSF82693 41 130 2.62E-20 T 10-11-2016 A4G23_RS06610 b5ff49755007fe0fd6393b755b686efd 1057 SUPERFAMILY SSF82693 271 326 5.23E-15 T 10-11-2016 A4G23_RS06610 b5ff49755007fe0fd6393b755b686efd 1057 SUPERFAMILY SSF82693 135 182 5.23E-15 T 10-11-2016 A4G23_RS06610 b5ff49755007fe0fd6393b755b686efd 1057 PRINTS PR00702 Acriflavin resistance protein family signature 11 35 1.7E-41 T 10-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A4G23_RS06610 b5ff49755007fe0fd6393b755b686efd 1057 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 1.7E-41 T 10-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A4G23_RS06610 b5ff49755007fe0fd6393b755b686efd 1057 PRINTS PR00702 Acriflavin resistance protein family signature 388 412 1.7E-41 T 10-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A4G23_RS06610 b5ff49755007fe0fd6393b755b686efd 1057 PRINTS PR00702 Acriflavin resistance protein family signature 466 489 1.7E-41 T 10-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A4G23_RS06610 b5ff49755007fe0fd6393b755b686efd 1057 PRINTS PR00702 Acriflavin resistance protein family signature 360 381 1.7E-41 T 10-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A4G23_RS06610 b5ff49755007fe0fd6393b755b686efd 1057 PRINTS PR00702 Acriflavin resistance protein family signature 441 464 1.7E-41 T 10-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A4G23_RS06610 b5ff49755007fe0fd6393b755b686efd 1057 PRINTS PR00702 Acriflavin resistance protein family signature 333 356 1.7E-41 T 10-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A4G23_RS06610 b5ff49755007fe0fd6393b755b686efd 1057 Gene3D G3DSA:3.30.70.1430 41 136 1.4E-22 T 10-11-2016 A4G23_RS06610 b5ff49755007fe0fd6393b755b686efd 1057 SUPERFAMILY SSF82866 295 494 7.19E-42 T 10-11-2016 A4G23_RS06610 b5ff49755007fe0fd6393b755b686efd 1057 Gene3D G3DSA:3.30.70.1430 567 651 2.2E-8 T 10-11-2016 A4G23_RS06610 b5ff49755007fe0fd6393b755b686efd 1057 SUPERFAMILY SSF82866 788 1013 1.57E-48 T 10-11-2016 A4G23_RS08440 44ef247a90315985f67c6fab9e3b5232 156 Gene3D G3DSA:1.10.10.10 4 153 1.2E-36 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS08440 44ef247a90315985f67c6fab9e3b5232 156 SUPERFAMILY SSF46785 9 153 1.16E-32 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS08440 44ef247a90315985f67c6fab9e3b5232 156 Pfam PF12802 MarR family 42 103 2.5E-12 T 10-11-2016 A4G23_RS08440 44ef247a90315985f67c6fab9e3b5232 156 SMART SM00347 36 139 1.4E-20 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS08440 44ef247a90315985f67c6fab9e3b5232 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 99 115 2.9E-15 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS08440 44ef247a90315985f67c6fab9e3b5232 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 130 150 2.9E-15 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS08440 44ef247a90315985f67c6fab9e3b5232 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 80 95 2.9E-15 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS08440 44ef247a90315985f67c6fab9e3b5232 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 63 79 2.9E-15 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS10610 2df0bd5e47f2e999c33535eb0d025fa7 316 Gene3D G3DSA:3.90.25.10 168 314 3.2E-43 T 10-11-2016 A4G23_RS10610 2df0bd5e47f2e999c33535eb0d025fa7 316 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 238 5.1E-54 T 10-11-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 A4G23_RS10610 2df0bd5e47f2e999c33535eb0d025fa7 316 Gene3D G3DSA:3.40.50.720 1 167 1.3E-44 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS10610 2df0bd5e47f2e999c33535eb0d025fa7 316 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 3 315 1.6E-111 T 10-11-2016 IPR005886 UDP-glucose 4-epimerase GalE GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 A4G23_RS10610 2df0bd5e47f2e999c33535eb0d025fa7 316 SUPERFAMILY SSF51735 1 314 7.38E-87 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS02655 bb1b063469cd541ac54b027084f0871f 452 SUPERFAMILY SSF53335 284 344 2.32E-58 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS02655 bb1b063469cd541ac54b027084f0871f 452 SUPERFAMILY SSF53335 9 251 2.32E-58 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS02655 bb1b063469cd541ac54b027084f0871f 452 Pfam PF00145 C-5 cytosine-specific DNA methylase 11 343 4.5E-51 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS02655 bb1b063469cd541ac54b027084f0871f 452 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 125 139 1.8E-11 T 10-11-2016 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 A4G23_RS02655 bb1b063469cd541ac54b027084f0871f 452 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 171 184 1.8E-11 T 10-11-2016 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 A4G23_RS02655 bb1b063469cd541ac54b027084f0871f 452 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 11 27 1.8E-11 T 10-11-2016 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 A4G23_RS02655 bb1b063469cd541ac54b027084f0871f 452 ProSitePatterns PS00094 C-5 cytosine-specific DNA methylases active site. 87 99 - T 10-11-2016 IPR018117 DNA methylase, C-5 cytosine-specific, active site KEGG: 00270+2.1.1.37|Reactome: R-HSA-212300|Reactome: R-HSA-5334118 A4G23_RS02655 bb1b063469cd541ac54b027084f0871f 452 ProSitePatterns PS00095 C-5 cytosine-specific DNA methylases C-terminal signature. 325 343 - T 10-11-2016 IPR031303 DNA methylase, C-5 cytosine-specific, conserved site KEGG: 00270+2.1.1.37 A4G23_RS02655 bb1b063469cd541ac54b027084f0871f 452 Gene3D G3DSA:3.40.50.150 6 219 1.5E-49 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS02655 bb1b063469cd541ac54b027084f0871f 452 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 12 208 1.1E-33 T 10-11-2016 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 A4G23_RS07225 083591824c56439771fcc9eeb82aab67 398 Gene3D G3DSA:1.10.101.10 325 393 1.4E-16 T 10-11-2016 IPR002477 Peptidoglycan binding-like A4G23_RS07225 083591824c56439771fcc9eeb82aab67 398 SUPERFAMILY SSF47090 326 392 5.49E-14 T 10-11-2016 IPR002477 Peptidoglycan binding-like A4G23_RS07225 083591824c56439771fcc9eeb82aab67 398 Pfam PF01471 Putative peptidoglycan binding domain 334 392 2.4E-10 T 10-11-2016 IPR002477 Peptidoglycan binding-like A4G23_RS02945 46fba8888ed2cca06b2324c181d89bfa 227 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 9 214 4.9E-78 T 10-11-2016 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4G23_RS02945 46fba8888ed2cca06b2324c181d89bfa 227 Pfam PF03167 Uracil DNA glycosylase superfamily 57 207 7.8E-22 T 10-11-2016 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4G23_RS02945 46fba8888ed2cca06b2324c181d89bfa 227 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 8 222 40.305 T 10-11-2016 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4G23_RS02945 46fba8888ed2cca06b2324c181d89bfa 227 SMART SM00987 52 211 9.2E-33 T 10-11-2016 A4G23_RS02945 46fba8888ed2cca06b2324c181d89bfa 227 SMART SM00986 52 211 9.2E-33 T 10-11-2016 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4G23_RS02945 46fba8888ed2cca06b2324c181d89bfa 227 SUPERFAMILY SSF52141 5 222 3.71E-88 T 10-11-2016 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4G23_RS02945 46fba8888ed2cca06b2324c181d89bfa 227 Gene3D G3DSA:3.40.470.10 6 223 3.3E-93 T 10-11-2016 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4G23_RS02945 46fba8888ed2cca06b2324c181d89bfa 227 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 60 69 - T 10-11-2016 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4G23_RS00250 96d4f659390e192f0668f7602d9b7c3b 95 Gene3D G3DSA:3.30.750.24 1 94 1.4E-26 T 10-11-2016 IPR002645 STAS domain A4G23_RS00250 96d4f659390e192f0668f7602d9b7c3b 95 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 1 89 1.0E-18 T 10-11-2016 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 A4G23_RS00250 96d4f659390e192f0668f7602d9b7c3b 95 Pfam PF13466 STAS domain 1 80 4.1E-14 T 10-11-2016 IPR002645 STAS domain A4G23_RS00250 96d4f659390e192f0668f7602d9b7c3b 95 SUPERFAMILY SSF52091 1 94 2.94E-21 T 10-11-2016 IPR002645 STAS domain A4G23_RS19595 e8d39b49801df15999dc2b1cc808f105 221 SUPERFAMILY SSF52172 2 130 1.32E-31 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS19595 e8d39b49801df15999dc2b1cc808f105 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 192 7.2E-13 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS19595 e8d39b49801df15999dc2b1cc808f105 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 192 204 7.2E-13 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS19595 e8d39b49801df15999dc2b1cc808f105 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 176 7.2E-13 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS19595 e8d39b49801df15999dc2b1cc808f105 221 Gene3D G3DSA:3.40.50.2300 2 121 3.2E-36 T 10-11-2016 A4G23_RS19595 e8d39b49801df15999dc2b1cc808f105 221 Pfam PF00072 Response regulator receiver domain 3 114 2.0E-23 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS19595 e8d39b49801df15999dc2b1cc808f105 221 SMART SM00448 1 113 2.1E-28 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS19595 e8d39b49801df15999dc2b1cc808f105 221 ProSitePatterns PS00622 LuxR-type HTH domain signature. 176 203 - T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS19595 e8d39b49801df15999dc2b1cc808f105 221 SMART SM00421 159 216 5.0E-25 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS19595 e8d39b49801df15999dc2b1cc808f105 221 Gene3D G3DSA:1.10.10.10 122 220 2.3E-29 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS19595 e8d39b49801df15999dc2b1cc808f105 221 Pfam PF00196 Bacterial regulatory proteins, luxR family 161 216 1.4E-18 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS19595 e8d39b49801df15999dc2b1cc808f105 221 SUPERFAMILY SSF46894 154 220 2.52E-20 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS14225 9585a82bf4ca03e0360503b0133e90f0 450 SMART SM00656 129 369 3.1E-38 T 10-11-2016 IPR002022 Pectate lyase/Amb allergen A4G23_RS14225 9585a82bf4ca03e0360503b0133e90f0 450 Pfam PF00544 Pectate lyase 146 362 7.7E-44 T 10-11-2016 IPR002022 Pectate lyase/Amb allergen A4G23_RS14225 9585a82bf4ca03e0360503b0133e90f0 450 SUPERFAMILY SSF51126 52 118 1.33E-64 T 10-11-2016 IPR011050 Pectin lyase fold/virulence factor A4G23_RS14225 9585a82bf4ca03e0360503b0133e90f0 450 SUPERFAMILY SSF51126 152 443 1.33E-64 T 10-11-2016 IPR011050 Pectin lyase fold/virulence factor A4G23_RS14225 9585a82bf4ca03e0360503b0133e90f0 450 Gene3D G3DSA:2.160.20.10 46 443 2.3E-103 T 10-11-2016 IPR012334 Pectin lyase fold A4G23_RS25095 2c41783cac5cd371b9458e964dcf2e64 517 Pfam PF01593 Flavin containing amine oxidoreductase 43 486 1.1E-39 T 10-11-2016 IPR002937 Amine oxidase GO:0016491|GO:0055114 A4G23_RS25095 2c41783cac5cd371b9458e964dcf2e64 517 SUPERFAMILY SSF51905 445 489 4.21E-42 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS25095 2c41783cac5cd371b9458e964dcf2e64 517 SUPERFAMILY SSF51905 32 346 4.21E-42 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS25095 2c41783cac5cd371b9458e964dcf2e64 517 PRINTS PR00419 Adrenodoxin reductase family signature 35 57 7.6E-6 T 10-11-2016 A4G23_RS25095 2c41783cac5cd371b9458e964dcf2e64 517 PRINTS PR00419 Adrenodoxin reductase family signature 58 71 7.6E-6 T 10-11-2016 A4G23_RS25095 2c41783cac5cd371b9458e964dcf2e64 517 Gene3D G3DSA:3.50.50.60 192 193 2.9E-27 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS25095 2c41783cac5cd371b9458e964dcf2e64 517 Gene3D G3DSA:3.50.50.60 432 486 2.9E-27 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS25095 2c41783cac5cd371b9458e964dcf2e64 517 Gene3D G3DSA:3.50.50.60 33 115 2.9E-27 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS25095 2c41783cac5cd371b9458e964dcf2e64 517 Gene3D G3DSA:3.50.50.60 237 329 2.9E-27 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS05310 103c3631800860856fb931179e797e35 504 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 309 489 4.2E-25 T 10-11-2016 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 A4G23_RS05310 103c3631800860856fb931179e797e35 504 SUPERFAMILY SSF52317 306 499 3.95E-30 T 10-11-2016 IPR029062 Class I glutamine amidotransferase-like A4G23_RS05310 103c3631800860856fb931179e797e35 504 Gene3D G3DSA:3.40.50.880 308 503 1.9E-29 T 10-11-2016 IPR029062 Class I glutamine amidotransferase-like A4G23_RS05310 103c3631800860856fb931179e797e35 504 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 192 2.5E-24 T 10-11-2016 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A4G23_RS05310 103c3631800860856fb931179e797e35 504 SUPERFAMILY SSF52540 4 196 1.12E-42 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05310 103c3631800860856fb931179e797e35 504 Gene3D G3DSA:3.40.50.300 4 193 2.2E-21 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05310 103c3631800860856fb931179e797e35 504 Hamap MF_00027 Cobyrinate a,c-diamide synthase [cbiA]. 2 492 41.936 T 10-11-2016 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 A4G23_RS26880 a8b3fffaa350abb141d86fe4d45f2f0d 515 SUPERFAMILY SSF56091 180 385 8.87E-46 T 10-11-2016 A4G23_RS26880 a8b3fffaa350abb141d86fe4d45f2f0d 515 Pfam PF04679 ATP dependent DNA ligase C terminal region 404 495 7.7E-14 T 10-11-2016 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 A4G23_RS26880 a8b3fffaa350abb141d86fe4d45f2f0d 515 SUPERFAMILY SSF117018 4 199 1.28E-28 T 10-11-2016 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 A4G23_RS26880 a8b3fffaa350abb141d86fe4d45f2f0d 515 Gene3D G3DSA:3.30.1490.70 185 212 5.6E-17 T 10-11-2016 A4G23_RS26880 a8b3fffaa350abb141d86fe4d45f2f0d 515 Gene3D G3DSA:3.30.1490.70 331 381 5.6E-17 T 10-11-2016 A4G23_RS26880 a8b3fffaa350abb141d86fe4d45f2f0d 515 TIGRFAM TIGR00574 dnl1: DNA ligase I, ATP-dependent (dnl1) 70 507 3.0E-75 T 10-11-2016 IPR000977 DNA ligase, ATP-dependent GO:0003910|GO:0005524|GO:0006281|GO:0006310|GO:0071897 A4G23_RS26880 a8b3fffaa350abb141d86fe4d45f2f0d 515 SUPERFAMILY SSF50249 387 506 2.17E-30 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS26880 a8b3fffaa350abb141d86fe4d45f2f0d 515 Gene3D G3DSA:2.40.50.140 388 506 6.0E-33 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS26880 a8b3fffaa350abb141d86fe4d45f2f0d 515 Gene3D G3DSA:1.10.3260.10 70 184 6.4E-18 T 10-11-2016 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 A4G23_RS26880 a8b3fffaa350abb141d86fe4d45f2f0d 515 Pfam PF01068 ATP dependent DNA ligase domain 186 385 1.2E-40 T 10-11-2016 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 A4G23_RS26880 a8b3fffaa350abb141d86fe4d45f2f0d 515 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 208 216 - T 10-11-2016 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 A4G23_RS26880 a8b3fffaa350abb141d86fe4d45f2f0d 515 Hamap MF_00407 DNA ligase [lig]. 1 511 26.014 T 10-11-2016 IPR022865 DNA ligase, ATP-dependent, bacterial/archaeal GO:0003910 A4G23_RS26880 a8b3fffaa350abb141d86fe4d45f2f0d 515 Gene3D G3DSA:3.30.470.30 213 327 7.1E-28 T 10-11-2016 A4G23_RS26880 a8b3fffaa350abb141d86fe4d45f2f0d 515 Pfam PF04675 DNA ligase N terminus 72 130 1.2E-6 T 10-11-2016 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 A4G23_RS04815 ed680474847e83215dfed6a079da6414 924 SMART SM00382 736 921 7.4E-8 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS04815 ed680474847e83215dfed6a079da6414 924 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 272 9.4E-19 T 10-11-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 A4G23_RS04815 ed680474847e83215dfed6a079da6414 924 Pfam PF02653 Branched-chain amino acid transport system / permease component 327 566 1.8E-19 T 10-11-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 A4G23_RS04815 ed680474847e83215dfed6a079da6414 924 Pfam PF00005 ABC transporter 727 872 4.3E-24 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS04815 ed680474847e83215dfed6a079da6414 924 Gene3D G3DSA:3.40.50.300 708 923 5.5E-57 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS04815 ed680474847e83215dfed6a079da6414 924 SUPERFAMILY SSF52540 711 923 4.71E-55 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS24105 1c3efcb65f51ddd6a7969e22b6bd8684 436 Gene3D G3DSA:3.40.640.10 68 317 4.3E-69 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS24105 1c3efcb65f51ddd6a7969e22b6bd8684 436 SUPERFAMILY SSF53383 23 433 1.9E-103 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS24105 1c3efcb65f51ddd6a7969e22b6bd8684 436 Pfam PF00202 Aminotransferase class-III 32 432 1.4E-85 T 10-11-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4G23_RS24105 1c3efcb65f51ddd6a7969e22b6bd8684 436 Gene3D G3DSA:3.90.1150.10 318 433 4.5E-35 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS19610 4c72655553bdd5e8b71082827d3029dd 190 Gene3D G3DSA:1.20.1200.10 16 188 4.8E-53 T 10-11-2016 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 A4G23_RS19610 4c72655553bdd5e8b71082827d3029dd 190 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 8 182 3.8E-47 T 10-11-2016 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 A4G23_RS19610 4c72655553bdd5e8b71082827d3029dd 190 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 13 184 2.0E-79 T 10-11-2016 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 A4G23_RS19610 4c72655553bdd5e8b71082827d3029dd 190 Pfam PF01923 Cobalamin adenosyltransferase 7 174 1.2E-51 T 10-11-2016 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 A4G23_RS19610 4c72655553bdd5e8b71082827d3029dd 190 SUPERFAMILY SSF89028 6 185 1.96E-53 T 10-11-2016 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 A4G23_RS07510 158a87bf691e4b7b103133ed6eb84963 420 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 6 253 1.4E-53 T 10-11-2016 IPR014030 Beta-ketoacyl synthase, N-terminal A4G23_RS07510 158a87bf691e4b7b103133ed6eb84963 420 SMART SM00825 Beta-ketoacyl synthase 8 411 5.7E-13 T 10-11-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4G23_RS07510 158a87bf691e4b7b103133ed6eb84963 420 Gene3D G3DSA:3.40.47.10 270 419 1.1E-49 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS07510 158a87bf691e4b7b103133ed6eb84963 420 SUPERFAMILY SSF53901 221 419 7.3E-62 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS07510 158a87bf691e4b7b103133ed6eb84963 420 Gene3D G3DSA:3.40.47.10 10 264 2.0E-65 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS07510 158a87bf691e4b7b103133ed6eb84963 420 SUPERFAMILY SSF53901 6 258 1.48E-66 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS07510 158a87bf691e4b7b103133ed6eb84963 420 PIRSF PIRSF000447 3 420 4.3E-143 T 10-11-2016 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 A4G23_RS07510 158a87bf691e4b7b103133ed6eb84963 420 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 261 375 5.5E-31 T 10-11-2016 IPR014031 Beta-ketoacyl synthase, C-terminal A4G23_RS07510 158a87bf691e4b7b103133ed6eb84963 420 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 6 418 4.5E-151 T 10-11-2016 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 A4G23_RS05940 564a45b7cf05d91907d2649b74429380 503 Pfam PF12796 Ankyrin repeats (3 copies) 56 135 2.7E-12 T 10-11-2016 IPR020683 Ankyrin repeat-containing domain A4G23_RS05940 564a45b7cf05d91907d2649b74429380 503 Gene3D G3DSA:1.25.10.10 265 499 3.7E-23 T 10-11-2016 IPR011989 Armadillo-like helical A4G23_RS05940 564a45b7cf05d91907d2649b74429380 503 Gene3D G3DSA:1.25.40.20 12 89 5.8E-18 T 10-11-2016 IPR020683 Ankyrin repeat-containing domain A4G23_RS05940 564a45b7cf05d91907d2649b74429380 503 Gene3D G3DSA:1.25.40.20 90 167 5.6E-21 T 10-11-2016 IPR020683 Ankyrin repeat-containing domain A4G23_RS05940 564a45b7cf05d91907d2649b74429380 503 SUPERFAMILY SSF48371 262 478 3.72E-20 T 10-11-2016 IPR016024 Armadillo-type fold GO:0005488 A4G23_RS05940 564a45b7cf05d91907d2649b74429380 503 SUPERFAMILY SSF48403 12 166 5.63E-34 T 10-11-2016 IPR020683 Ankyrin repeat-containing domain A4G23_RS05940 564a45b7cf05d91907d2649b74429380 503 SMART SM00248 40 69 0.011 T 10-11-2016 IPR002110 Ankyrin repeat GO:0005515 A4G23_RS05940 564a45b7cf05d91907d2649b74429380 503 SMART SM00248 141 172 79.0 T 10-11-2016 IPR002110 Ankyrin repeat GO:0005515 A4G23_RS05940 564a45b7cf05d91907d2649b74429380 503 SMART SM00248 108 137 0.0053 T 10-11-2016 IPR002110 Ankyrin repeat GO:0005515 A4G23_RS05940 564a45b7cf05d91907d2649b74429380 503 SMART SM00248 75 104 0.05 T 10-11-2016 IPR002110 Ankyrin repeat GO:0005515 A4G23_RS15385 149f4ac01b39f6c318b3d1aaaa537640 625 SUPERFAMILY SSF56425 240 357 1.5E-37 T 10-11-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4G23_RS15385 149f4ac01b39f6c318b3d1aaaa537640 625 Gene3D G3DSA:1.20.58.100 491 594 3.5E-23 T 10-11-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4G23_RS15385 149f4ac01b39f6c318b3d1aaaa537640 625 SUPERFAMILY SSF46977 491 614 7.98E-28 T 10-11-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4G23_RS15385 149f4ac01b39f6c318b3d1aaaa537640 625 Pfam PF00890 FAD binding domain 18 397 2.3E-98 T 10-11-2016 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4G23_RS15385 149f4ac01b39f6c318b3d1aaaa537640 625 Gene3D G3DSA:3.90.700.10 246 353 3.6E-36 T 10-11-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4G23_RS15385 149f4ac01b39f6c318b3d1aaaa537640 625 SUPERFAMILY SSF51905 5 269 1.59E-66 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS15385 149f4ac01b39f6c318b3d1aaaa537640 625 SUPERFAMILY SSF51905 361 427 1.59E-66 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS15385 149f4ac01b39f6c318b3d1aaaa537640 625 PIRSF PIRSF000171 13 606 1.2E-36 T 10-11-2016 IPR030664 Succinate dehydrogenase/fumarate reductase, alpha/adenylylsulphate reductase subunit Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4G23_RS15385 149f4ac01b39f6c318b3d1aaaa537640 625 Gene3D G3DSA:3.50.50.60 13 245 5.1E-100 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS15385 149f4ac01b39f6c318b3d1aaaa537640 625 Gene3D G3DSA:3.50.50.60 354 415 5.1E-100 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS15385 149f4ac01b39f6c318b3d1aaaa537640 625 Pfam PF02910 Fumarate reductase flavoprotein C-term 493 612 1.6E-19 T 10-11-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4G23_RS15385 149f4ac01b39f6c318b3d1aaaa537640 625 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 17 420 2.8E-151 T 10-11-2016 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 A4G23_RS15385 149f4ac01b39f6c318b3d1aaaa537640 625 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 18 40 2.9E-6 T 10-11-2016 A4G23_RS15385 149f4ac01b39f6c318b3d1aaaa537640 625 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 375 382 2.9E-6 T 10-11-2016 A4G23_RS15385 149f4ac01b39f6c318b3d1aaaa537640 625 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 360 382 1.4E-10 T 10-11-2016 A4G23_RS15385 149f4ac01b39f6c318b3d1aaaa537640 625 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 19 38 1.4E-10 T 10-11-2016 A4G23_RS10400 54dc8dae1d378b5512c6c868f85104fe 423 PRINTS PR00359 B-class P450 signature 199 221 1.4E-58 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS10400 54dc8dae1d378b5512c6c868f85104fe 423 PRINTS PR00359 B-class P450 signature 331 346 1.4E-58 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS10400 54dc8dae1d378b5512c6c868f85104fe 423 PRINTS PR00359 B-class P450 signature 303 330 1.4E-58 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS10400 54dc8dae1d378b5512c6c868f85104fe 423 PRINTS PR00359 B-class P450 signature 161 176 1.4E-58 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS10400 54dc8dae1d378b5512c6c868f85104fe 423 PRINTS PR00359 B-class P450 signature 361 372 1.4E-58 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS10400 54dc8dae1d378b5512c6c868f85104fe 423 PRINTS PR00359 B-class P450 signature 98 109 1.4E-58 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS10400 54dc8dae1d378b5512c6c868f85104fe 423 PRINTS PR00359 B-class P450 signature 352 361 1.4E-58 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS10400 54dc8dae1d378b5512c6c868f85104fe 423 PRINTS PR00359 B-class P450 signature 285 296 1.4E-58 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS10400 54dc8dae1d378b5512c6c868f85104fe 423 PRINTS PR00359 B-class P450 signature 144 160 1.4E-58 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS10400 54dc8dae1d378b5512c6c868f85104fe 423 SUPERFAMILY SSF48264 15 414 4.32E-102 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS10400 54dc8dae1d378b5512c6c868f85104fe 423 Gene3D G3DSA:1.10.630.10 12 416 3.1E-134 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS10400 54dc8dae1d378b5512c6c868f85104fe 423 Pfam PF00067 Cytochrome P450 192 381 6.9E-19 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS11110 eaa3afeea2c1e21669fdf7c02c87fb71 297 SUPERFAMILY SSF47413 7 73 3.84E-14 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS11110 eaa3afeea2c1e21669fdf7c02c87fb71 297 Pfam PF13560 Helix-turn-helix domain 13 69 1.5E-17 T 10-11-2016 A4G23_RS11110 eaa3afeea2c1e21669fdf7c02c87fb71 297 Gene3D G3DSA:1.10.260.40 6 73 7.8E-18 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS11110 eaa3afeea2c1e21669fdf7c02c87fb71 297 SMART SM00530 17 72 5.0E-14 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS02185 f98de268ef7ba3e520698875bb2610d1 480 SUPERFAMILY SSF75005 5 291 6.57E-81 T 10-11-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain A4G23_RS02185 f98de268ef7ba3e520698875bb2610d1 480 Gene3D G3DSA:2.115.10.20 7 295 4.4E-84 T 10-11-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain A4G23_RS02185 f98de268ef7ba3e520698875bb2610d1 480 Pfam PF04616 Glycosyl hydrolases family 43 6 284 3.7E-79 T 10-11-2016 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 A4G23_RS02185 f98de268ef7ba3e520698875bb2610d1 480 Gene3D G3DSA:2.60.120.200 299 475 1.7E-27 T 10-11-2016 IPR013320 Concanavalin A-like lectin/glucanase domain A4G23_RS02185 f98de268ef7ba3e520698875bb2610d1 480 SUPERFAMILY SSF49899 297 475 2.73E-28 T 10-11-2016 IPR013320 Concanavalin A-like lectin/glucanase domain A4G23_RS11840 11c0c1e6e9f14f8720db1b11ba3f654c 247 Pfam PF00005 ABC transporter 28 167 5.4E-26 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS11840 11c0c1e6e9f14f8720db1b11ba3f654c 247 Gene3D G3DSA:3.40.50.300 5 225 3.2E-63 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS11840 11c0c1e6e9f14f8720db1b11ba3f654c 247 SUPERFAMILY SSF52540 9 225 2.13E-59 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS11840 11c0c1e6e9f14f8720db1b11ba3f654c 247 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS11840 11c0c1e6e9f14f8720db1b11ba3f654c 247 SMART SM00382 36 215 6.8E-15 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS13075 f16c6572b26582ac85e4c34ec9ced896 709 Pfam PF13581 Histidine kinase-like ATPase domain 584 694 2.2E-9 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS13075 f16c6572b26582ac85e4c34ec9ced896 709 SMART SM00331 319 565 1.4E-38 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS13075 f16c6572b26582ac85e4c34ec9ced896 709 SMART SM00065 138 301 0.0037 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS13075 f16c6572b26582ac85e4c34ec9ced896 709 Gene3D G3DSA:3.30.450.40 136 294 5.3E-15 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS13075 f16c6572b26582ac85e4c34ec9ced896 709 Pfam PF13185 GAF domain 154 291 1.9E-11 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS13075 f16c6572b26582ac85e4c34ec9ced896 709 SUPERFAMILY SSF55785 8 118 4.82E-6 T 10-11-2016 IPR000014 PAS domain A4G23_RS13075 f16c6572b26582ac85e4c34ec9ced896 709 Gene3D G3DSA:3.30.450.20 4 115 2.4E-10 T 10-11-2016 A4G23_RS13075 f16c6572b26582ac85e4c34ec9ced896 709 SUPERFAMILY SSF81606 335 563 4.45E-8 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS13075 f16c6572b26582ac85e4c34ec9ced896 709 SUPERFAMILY SSF55781 155 303 5.02E-14 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS13075 f16c6572b26582ac85e4c34ec9ced896 709 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 348 565 9.1E-50 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS16650 eb511dcfb5cbf2fde779d985800eeaf1 94 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 14 92 25.046 T 10-11-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS16650 eb511dcfb5cbf2fde779d985800eeaf1 94 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 21 87 9.0E-32 T 10-11-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS16650 eb511dcfb5cbf2fde779d985800eeaf1 94 PRINTS PR00973 Ribosomal protein S17 family signature 35 58 1.3E-11 T 10-11-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS16650 eb511dcfb5cbf2fde779d985800eeaf1 94 PRINTS PR00973 Ribosomal protein S17 family signature 77 84 1.3E-11 T 10-11-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS16650 eb511dcfb5cbf2fde779d985800eeaf1 94 PRINTS PR00973 Ribosomal protein S17 family signature 67 77 1.3E-11 T 10-11-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS16650 eb511dcfb5cbf2fde779d985800eeaf1 94 Pfam PF00366 Ribosomal protein S17 21 88 1.9E-30 T 10-11-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS16650 eb511dcfb5cbf2fde779d985800eeaf1 94 Gene3D G3DSA:2.40.50.140 16 93 5.5E-35 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS16650 eb511dcfb5cbf2fde779d985800eeaf1 94 SUPERFAMILY SSF50249 16 93 1.29E-30 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS16650 eb511dcfb5cbf2fde779d985800eeaf1 94 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 16 87 1.2E-34 T 10-11-2016 IPR019984 Ribosomal protein S17, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS16650 eb511dcfb5cbf2fde779d985800eeaf1 94 ProSitePatterns PS00056 Ribosomal protein S17 signature. 67 79 - T 10-11-2016 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS16620 4d0fcfc9a28270d0acb8f16d4b2c2c13 278 SUPERFAMILY SSF50104 127 271 1.14E-56 T 10-11-2016 IPR008991 Translation protein SH3-like domain A4G23_RS16620 4d0fcfc9a28270d0acb8f16d4b2c2c13 278 ProSitePatterns PS00467 Ribosomal protein L2 signature. 219 230 - T 10-11-2016 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS16620 4d0fcfc9a28270d0acb8f16d4b2c2c13 278 Gene3D G3DSA:2.40.50.140 1 115 6.8E-52 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS16620 4d0fcfc9a28270d0acb8f16d4b2c2c13 278 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 126 251 1.2E-55 T 10-11-2016 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 A4G23_RS16620 4d0fcfc9a28270d0acb8f16d4b2c2c13 278 SMART SM01382 125 253 1.1E-89 T 10-11-2016 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 A4G23_RS16620 4d0fcfc9a28270d0acb8f16d4b2c2c13 278 PIRSF PIRSF002158 4 275 5.2E-96 T 10-11-2016 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS16620 4d0fcfc9a28270d0acb8f16d4b2c2c13 278 SMART SM01383 42 119 2.1E-40 T 10-11-2016 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS16620 4d0fcfc9a28270d0acb8f16d4b2c2c13 278 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 118 1.2E-32 T 10-11-2016 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS16620 4d0fcfc9a28270d0acb8f16d4b2c2c13 278 Gene3D G3DSA:2.30.30.30 120 196 5.7E-30 T 10-11-2016 IPR014722 Ribosomal protein L2 domain 2 A4G23_RS16620 4d0fcfc9a28270d0acb8f16d4b2c2c13 278 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 273 7.8E-128 T 10-11-2016 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS16620 4d0fcfc9a28270d0acb8f16d4b2c2c13 278 Gene3D G3DSA:4.10.950.10 197 273 4.5E-33 T 10-11-2016 IPR014726 Ribosomal protein L2, domain 3 A4G23_RS16620 4d0fcfc9a28270d0acb8f16d4b2c2c13 278 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 273 47.963 T 10-11-2016 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS16620 4d0fcfc9a28270d0acb8f16d4b2c2c13 278 SUPERFAMILY SSF50249 3 126 2.06E-49 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS13495 3324e98c04a411c5cbbe4429ef512ef4 236 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 27 197 8.1E-39 T 10-11-2016 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 A4G23_RS13495 3324e98c04a411c5cbbe4429ef512ef4 236 Pfam PF02527 rRNA small subunit methyltransferase G 25 198 2.0E-55 T 10-11-2016 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 A4G23_RS13495 3324e98c04a411c5cbbe4429ef512ef4 236 SUPERFAMILY SSF53335 25 208 3.13E-31 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS13495 3324e98c04a411c5cbbe4429ef512ef4 236 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 14 194 24.51 T 10-11-2016 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 A4G23_RS13495 3324e98c04a411c5cbbe4429ef512ef4 236 Gene3D G3DSA:3.40.50.150 26 212 2.5E-61 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS20090 b523de393e7f76e58e3c0312ea5132dc 804 Gene3D G3DSA:1.20.1640.10 549 768 3.4E-27 T 10-11-2016 A4G23_RS20090 b523de393e7f76e58e3c0312ea5132dc 804 Gene3D G3DSA:1.20.1640.10 221 407 7.2E-29 T 10-11-2016 A4G23_RS20090 b523de393e7f76e58e3c0312ea5132dc 804 Pfam PF03176 MMPL family 529 768 7.0E-29 T 10-11-2016 IPR004869 Membrane transport protein, MMPL domain GO:0016020 A4G23_RS20090 b523de393e7f76e58e3c0312ea5132dc 804 Pfam PF03176 MMPL family 44 436 2.5E-64 T 10-11-2016 IPR004869 Membrane transport protein, MMPL domain GO:0016020 A4G23_RS20090 b523de393e7f76e58e3c0312ea5132dc 804 SUPERFAMILY SSF82866 526 764 3.79E-25 T 10-11-2016 A4G23_RS20090 b523de393e7f76e58e3c0312ea5132dc 804 SUPERFAMILY SSF82866 182 399 1.44E-30 T 10-11-2016 A4G23_RS09145 76edb853853d8df6f93482a8904418ba 188 Gene3D G3DSA:1.10.357.10 7 175 1.4E-29 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS09145 76edb853853d8df6f93482a8904418ba 188 SUPERFAMILY SSF48498 84 185 1.48E-15 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS09145 76edb853853d8df6f93482a8904418ba 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 63 5.7E-10 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS09145 76edb853853d8df6f93482a8904418ba 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 8.9E-6 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS09145 76edb853853d8df6f93482a8904418ba 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 8.9E-6 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS09145 76edb853853d8df6f93482a8904418ba 188 SUPERFAMILY SSF46689 4 88 7.18E-16 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS00355 05aa420f67c22dd5bbbaa112c7d6d5dd 368 TIGRFAM TIGR04036 LLM_CE1758_fam: putative luciferase-like monooxygenase, FMN-dependent, CE1758 family 1 354 9.2E-213 T 10-11-2016 IPR023934 Luciferase-like monooxygenase, FMN-dependent, putative A4G23_RS00355 05aa420f67c22dd5bbbaa112c7d6d5dd 368 SUPERFAMILY SSF51679 1 333 4.97E-72 T 10-11-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4G23_RS00355 05aa420f67c22dd5bbbaa112c7d6d5dd 368 Gene3D G3DSA:3.20.20.30 1 336 6.3E-81 T 10-11-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4G23_RS00355 05aa420f67c22dd5bbbaa112c7d6d5dd 368 Pfam PF00296 Luciferase-like monooxygenase 1 297 2.3E-58 T 10-11-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4G23_RS13665 7f88f73a1baa1b54ccffe360f1f7e667 73 ProDom PD267558 MEMBRANE TRANSMEMBRANE SPANNING SCO3924 4 33 3.0E-7 T 10-11-2016 IPR020246 Uncharacterised protein family SCO3924 A4G23_RS15020 76994c725a8f675d6bbe2e4293061165 216 PIRSF PIRSF006324 3 209 1.6E-42 T 10-11-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 A4G23_RS15020 76994c725a8f675d6bbe2e4293061165 216 Pfam PF01810 LysE type translocator 17 206 4.2E-29 T 10-11-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 A4G23_RS23255 ee550b2a809d87dd2203b6235c24ba6e 517 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 60 264 9.4E-26 T 10-11-2016 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 A4G23_RS23255 ee550b2a809d87dd2203b6235c24ba6e 517 Gene3D G3DSA:2.40.37.10 311 491 1.4E-26 T 10-11-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A4G23_RS23255 ee550b2a809d87dd2203b6235c24ba6e 517 Gene3D G3DSA:3.20.20.10 45 274 6.9E-42 T 10-11-2016 IPR029066 PLP-binding barrel A4G23_RS23255 ee550b2a809d87dd2203b6235c24ba6e 517 SUPERFAMILY SSF51419 42 272 3.49E-36 T 10-11-2016 IPR029066 PLP-binding barrel A4G23_RS23255 ee550b2a809d87dd2203b6235c24ba6e 517 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 66 84 - T 10-11-2016 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site A4G23_RS23255 ee550b2a809d87dd2203b6235c24ba6e 517 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 337 356 5.1E-8 T 10-11-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A4G23_RS23255 ee550b2a809d87dd2203b6235c24ba6e 517 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 66 84 5.1E-8 T 10-11-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A4G23_RS23255 ee550b2a809d87dd2203b6235c24ba6e 517 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 90 102 5.1E-8 T 10-11-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A4G23_RS23255 ee550b2a809d87dd2203b6235c24ba6e 517 SUPERFAMILY SSF50621 428 492 2.62E-10 T 10-11-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A4G23_RS14145 cb2e69dd69c62bbe82df2baa38c65eba 150 SUPERFAMILY SSF49777 4 139 4.32E-37 T 10-11-2016 IPR008914 Phosphatidylethanolamine-binding protein A4G23_RS14145 cb2e69dd69c62bbe82df2baa38c65eba 150 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 21 148 4.2E-24 T 10-11-2016 IPR005247 YbhB/YbcL A4G23_RS14145 cb2e69dd69c62bbe82df2baa38c65eba 150 Pfam PF01161 Phosphatidylethanolamine-binding protein 17 148 6.3E-29 T 10-11-2016 IPR008914 Phosphatidylethanolamine-binding protein A4G23_RS14145 cb2e69dd69c62bbe82df2baa38c65eba 150 Gene3D G3DSA:3.90.280.10 4 150 1.7E-42 T 10-11-2016 IPR008914 Phosphatidylethanolamine-binding protein A4G23_RS17035 231c4cf10e4532e561fc0640c61d9855 332 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 292 328 0.0014 T 10-11-2016 IPR019931 LPXTG cell wall anchor domain A4G23_RS12880 9b42492d9ff55571cc042dc2aa4753c7 508 Gene3D G3DSA:3.40.50.2020 290 456 2.7E-44 T 10-11-2016 IPR029057 Phosphoribosyltransferase-like A4G23_RS12880 9b42492d9ff55571cc042dc2aa4753c7 508 SUPERFAMILY SSF56235 23 286 1.37E-63 T 10-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal A4G23_RS12880 9b42492d9ff55571cc042dc2aa4753c7 508 SUPERFAMILY SSF53271 268 482 6.03E-68 T 10-11-2016 IPR029057 Phosphoribosyltransferase-like A4G23_RS12880 9b42492d9ff55571cc042dc2aa4753c7 508 Pfam PF13522 Glutamine amidotransferase domain 83 227 8.2E-16 T 10-11-2016 A4G23_RS12880 9b42492d9ff55571cc042dc2aa4753c7 508 PIRSF PIRSF000485 19 485 1.8E-160 T 10-11-2016 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 A4G23_RS12880 9b42492d9ff55571cc042dc2aa4753c7 508 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 22 475 46.377 T 10-11-2016 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 A4G23_RS12880 9b42492d9ff55571cc042dc2aa4753c7 508 Pfam PF00156 Phosphoribosyl transferase domain 297 403 8.0E-7 T 10-11-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 A4G23_RS12880 9b42492d9ff55571cc042dc2aa4753c7 508 Gene3D G3DSA:3.60.20.10 23 274 1.4E-67 T 10-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal A4G23_RS12880 9b42492d9ff55571cc042dc2aa4753c7 508 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 23 474 1.6E-156 T 10-11-2016 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 A4G23_RS05770 dcde9adfd6dfc5aaabf93dbe0376d3e2 296 Gene3D G3DSA:3.40.1190.20 4 294 1.2E-65 T 10-11-2016 IPR029056 Ribokinase-like A4G23_RS05770 dcde9adfd6dfc5aaabf93dbe0376d3e2 296 Pfam PF00294 pfkB family carbohydrate kinase 5 293 8.6E-52 T 10-11-2016 IPR011611 Carbohydrate kinase PfkB A4G23_RS05770 dcde9adfd6dfc5aaabf93dbe0376d3e2 296 SUPERFAMILY SSF53613 4 295 1.08E-64 T 10-11-2016 IPR029056 Ribokinase-like A4G23_RS05770 dcde9adfd6dfc5aaabf93dbe0376d3e2 296 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 251 264 - T 10-11-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A4G23_RS15390 609b6685a1d86144e978b4a4b7f4ead5 347 SUPERFAMILY SSF51690 177 342 1.65E-58 T 10-11-2016 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 A4G23_RS15390 609b6685a1d86144e978b4a4b7f4ead5 347 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 177 341 4.9E-59 T 10-11-2016 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 A4G23_RS15390 609b6685a1d86144e978b4a4b7f4ead5 347 Gene3D G3DSA:3.20.20.70 198 332 3.6E-59 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS15390 609b6685a1d86144e978b4a4b7f4ead5 347 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 78 341 3.4E-93 T 10-11-2016 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 A4G23_RS15390 609b6685a1d86144e978b4a4b7f4ead5 347 Gene3D G3DSA:3.90.1170.20 67 197 7.1E-45 T 10-11-2016 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 A4G23_RS15390 609b6685a1d86144e978b4a4b7f4ead5 347 SUPERFAMILY SSF54675 67 176 1.88E-26 T 10-11-2016 A4G23_RS15390 609b6685a1d86144e978b4a4b7f4ead5 347 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 88 175 3.1E-23 T 10-11-2016 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 A4G23_RS16675 bb754e56f90ed697aa21d76ec810bf00 132 Pfam PF00410 Ribosomal protein S8 5 132 1.5E-49 T 10-11-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS16675 bb754e56f90ed697aa21d76ec810bf00 132 Gene3D G3DSA:3.30.1490.10 76 132 1.7E-28 T 10-11-2016 A4G23_RS16675 bb754e56f90ed697aa21d76ec810bf00 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 30.795 T 10-11-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS16675 bb754e56f90ed697aa21d76ec810bf00 132 SUPERFAMILY SSF56047 3 132 3.4E-44 T 10-11-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS16675 bb754e56f90ed697aa21d76ec810bf00 132 Gene3D G3DSA:3.30.1370.30 2 72 3.4E-28 T 10-11-2016 A4G23_RS02425 07cf9d05218cbb4be1a24d4be2099c53 162 Gene3D G3DSA:3.40.30.10 1 159 6.7E-61 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS02425 07cf9d05218cbb4be1a24d4be2099c53 162 SUPERFAMILY SSF52833 1 159 1.58E-54 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS02425 07cf9d05218cbb4be1a24d4be2099c53 162 Pfam PF00255 Glutathione peroxidase 3 109 1.5E-39 T 10-11-2016 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 A4G23_RS02425 07cf9d05218cbb4be1a24d4be2099c53 162 PIRSF PIRSF000303 1 162 3.9E-60 T 10-11-2016 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 A4G23_RS02425 07cf9d05218cbb4be1a24d4be2099c53 162 PRINTS PR01011 Glutathione peroxidase family signature 21 38 4.9E-20 T 10-11-2016 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 A4G23_RS02425 07cf9d05218cbb4be1a24d4be2099c53 162 PRINTS PR01011 Glutathione peroxidase family signature 56 72 4.9E-20 T 10-11-2016 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 A4G23_RS02425 07cf9d05218cbb4be1a24d4be2099c53 162 PRINTS PR01011 Glutathione peroxidase family signature 122 131 4.9E-20 T 10-11-2016 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 A4G23_RS02425 07cf9d05218cbb4be1a24d4be2099c53 162 ProSitePatterns PS00460 Glutathione peroxidases active site. 23 38 - T 10-11-2016 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 A4G23_RS05470 b11108d41a3ab04c05e1f0d395dc2b5e 229 Gene3D G3DSA:1.10.10.10 9 75 1.8E-22 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS05470 b11108d41a3ab04c05e1f0d395dc2b5e 229 SUPERFAMILY SSF48008 83 204 2.22E-23 T 10-11-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal A4G23_RS05470 b11108d41a3ab04c05e1f0d395dc2b5e 229 SUPERFAMILY SSF46785 11 100 2.56E-18 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS05470 b11108d41a3ab04c05e1f0d395dc2b5e 229 SMART SM00895 84 203 7.8E-17 T 10-11-2016 IPR011711 GntR, C-terminal A4G23_RS05470 b11108d41a3ab04c05e1f0d395dc2b5e 229 SMART SM00345 16 74 3.5E-15 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS05470 b11108d41a3ab04c05e1f0d395dc2b5e 229 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 74 6.3E-17 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS05470 b11108d41a3ab04c05e1f0d395dc2b5e 229 Pfam PF07729 FCD domain 84 203 9.8E-23 T 10-11-2016 IPR011711 GntR, C-terminal A4G23_RS05470 b11108d41a3ab04c05e1f0d395dc2b5e 229 Gene3D G3DSA:1.20.120.530 78 205 1.9E-30 T 10-11-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal A4G23_RS25865 87b417afb1ed57fa11e15d00516a38d1 415 Pfam PF13416 Bacterial extracellular solute-binding protein 53 349 4.4E-36 T 10-11-2016 A4G23_RS25865 87b417afb1ed57fa11e15d00516a38d1 415 Gene3D G3DSA:3.40.190.10 161 349 1.1E-40 T 10-11-2016 A4G23_RS25865 87b417afb1ed57fa11e15d00516a38d1 415 SUPERFAMILY SSF53850 33 410 5.72E-65 T 10-11-2016 A4G23_RS25865 87b417afb1ed57fa11e15d00516a38d1 415 Gene3D G3DSA:3.40.190.10 32 160 5.2E-20 T 10-11-2016 A4G23_RS18810 4453977e1e71a79cad70a459b568cd50 579 PRINTS PR01217 Proline rich extensin signature 199 215 6.9E-9 T 10-11-2016 A4G23_RS18810 4453977e1e71a79cad70a459b568cd50 579 PRINTS PR01217 Proline rich extensin signature 239 251 6.9E-9 T 10-11-2016 A4G23_RS18810 4453977e1e71a79cad70a459b568cd50 579 PRINTS PR01217 Proline rich extensin signature 252 273 6.9E-9 T 10-11-2016 A4G23_RS18810 4453977e1e71a79cad70a459b568cd50 579 PRINTS PR01217 Proline rich extensin signature 178 190 6.9E-9 T 10-11-2016 A4G23_RS18810 4453977e1e71a79cad70a459b568cd50 579 SUPERFAMILY SSF51219 379 578 1.05E-31 T 10-11-2016 IPR016031 Tryptophan RNA-binding attenuator protein-like domain A4G23_RS18810 4453977e1e71a79cad70a459b568cd50 579 Gene3D G3DSA:3.60.160.10 381 575 3.1E-27 T 10-11-2016 IPR002838 Mitochondrial biogenesis protein AIM24 A4G23_RS18810 4453977e1e71a79cad70a459b568cd50 579 Gene3D G3DSA:2.60.60.30 30 167 2.0E-29 T 10-11-2016 A4G23_RS18810 4453977e1e71a79cad70a459b568cd50 579 Pfam PF01987 Mitochondrial biogenesis AIM24 383 575 2.9E-21 T 10-11-2016 IPR002838 Mitochondrial biogenesis protein AIM24 A4G23_RS18810 4453977e1e71a79cad70a459b568cd50 579 Pfam PF02342 TerD domain 1 170 1.6E-37 T 10-11-2016 IPR003325 TerD domain GO:0006950 A4G23_RS21960 1d6a0effc07ec91ff2eb2c235b80107e 687 SUPERFAMILY SSF49452 595 686 1.67E-29 T 10-11-2016 IPR013784 Carbohydrate-binding-like fold GO:0030246 A4G23_RS21960 1d6a0effc07ec91ff2eb2c235b80107e 687 Pfam PF03423 Carbohydrate binding domain (family 25) 490 583 1.1E-30 T 10-11-2016 IPR005085 Carbohydrate binding module family 25 GO:2001070 A4G23_RS21960 1d6a0effc07ec91ff2eb2c235b80107e 687 Pfam PF00686 Starch binding domain 595 680 6.2E-27 T 10-11-2016 IPR002044 Carbohydrate binding module family 20 GO:2001070 A4G23_RS21960 1d6a0effc07ec91ff2eb2c235b80107e 687 SUPERFAMILY SSF51445 44 391 1.49E-79 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS21960 1d6a0effc07ec91ff2eb2c235b80107e 687 Gene3D G3DSA:2.60.40.10 595 686 9.8E-29 T 10-11-2016 IPR013783 Immunoglobulin-like fold A4G23_RS21960 1d6a0effc07ec91ff2eb2c235b80107e 687 Gene3D G3DSA:3.20.20.80 40 393 3.7E-96 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS21960 1d6a0effc07ec91ff2eb2c235b80107e 687 Gene3D G3DSA:2.60.40.1180 396 484 1.2E-31 T 10-11-2016 IPR013780 Glycosyl hydrolase, all-beta A4G23_RS21960 1d6a0effc07ec91ff2eb2c235b80107e 687 SMART SM00632 398 484 6.1E-43 T 10-11-2016 IPR031319 Alpha-amylase, C-terminal domain Reactome: R-HSA-189085 A4G23_RS21960 1d6a0effc07ec91ff2eb2c235b80107e 687 SMART SM01065 595 683 4.1E-27 T 10-11-2016 IPR002044 Carbohydrate binding module family 20 GO:2001070 A4G23_RS21960 1d6a0effc07ec91ff2eb2c235b80107e 687 SMART SM00642 46 389 2.5E-76 T 10-11-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A4G23_RS21960 1d6a0effc07ec91ff2eb2c235b80107e 687 SUPERFAMILY SSF51011 394 485 2.46E-31 T 10-11-2016 A4G23_RS21960 1d6a0effc07ec91ff2eb2c235b80107e 687 PRINTS PR00110 Alpha-amylase signature 89 106 5.7E-18 T 10-11-2016 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 A4G23_RS21960 1d6a0effc07ec91ff2eb2c235b80107e 687 PRINTS PR00110 Alpha-amylase signature 245 263 5.7E-18 T 10-11-2016 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 A4G23_RS21960 1d6a0effc07ec91ff2eb2c235b80107e 687 PRINTS PR00110 Alpha-amylase signature 216 227 5.7E-18 T 10-11-2016 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 A4G23_RS21960 1d6a0effc07ec91ff2eb2c235b80107e 687 PRINTS PR00110 Alpha-amylase signature 121 132 5.7E-18 T 10-11-2016 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 A4G23_RS21960 1d6a0effc07ec91ff2eb2c235b80107e 687 PRINTS PR00110 Alpha-amylase signature 303 315 5.7E-18 T 10-11-2016 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 A4G23_RS21960 1d6a0effc07ec91ff2eb2c235b80107e 687 Pfam PF00128 Alpha amylase, catalytic domain 98 356 1.5E-18 T 10-11-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A4G23_RS21960 1d6a0effc07ec91ff2eb2c235b80107e 687 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 401 481 1.5E-13 T 10-11-2016 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 A4G23_RS21960 1d6a0effc07ec91ff2eb2c235b80107e 687 SMART SM01066 491 570 9.0E-23 T 10-11-2016 IPR005085 Carbohydrate binding module family 25 GO:2001070 A4G23_RS02405 cf685c524df4fd7c7154edbe99ff7fa0 595 Pfam PF00664 ABC transporter transmembrane region 46 313 9.5E-26 T 10-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A4G23_RS02405 cf685c524df4fd7c7154edbe99ff7fa0 595 SMART SM00382 381 567 6.9E-14 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS02405 cf685c524df4fd7c7154edbe99ff7fa0 595 SUPERFAMILY SSF90123 32 343 1.22E-52 T 10-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A4G23_RS02405 cf685c524df4fd7c7154edbe99ff7fa0 595 Gene3D G3DSA:1.20.1560.10 33 343 5.2E-52 T 10-11-2016 A4G23_RS02405 cf685c524df4fd7c7154edbe99ff7fa0 595 Gene3D G3DSA:3.40.50.300 356 585 3.1E-59 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS02405 cf685c524df4fd7c7154edbe99ff7fa0 595 Pfam PF00005 ABC transporter 372 521 4.9E-24 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS02405 cf685c524df4fd7c7154edbe99ff7fa0 595 SUPERFAMILY SSF52540 353 591 4.26E-67 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS26055 fc6d39ecdbdff59ed3cab8f63eb7fd79 271 SUPERFAMILY SSF53335 91 249 6.97E-23 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS26055 fc6d39ecdbdff59ed3cab8f63eb7fd79 271 Pfam PF08242 Methyltransferase domain 103 204 8.9E-13 T 10-11-2016 IPR013217 Methyltransferase type 12 A4G23_RS26055 fc6d39ecdbdff59ed3cab8f63eb7fd79 271 Gene3D G3DSA:3.40.50.150 89 250 6.1E-19 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS22150 b5722a1f930d4656bbc0384485aa74b0 248 Pfam PF13649 Methyltransferase domain 47 142 1.5E-23 T 10-11-2016 A4G23_RS22150 b5722a1f930d4656bbc0384485aa74b0 248 SUPERFAMILY SSF53335 11 247 1.67E-44 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS22150 b5722a1f930d4656bbc0384485aa74b0 248 Gene3D G3DSA:3.40.50.150 15 227 4.6E-41 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS16935 9d7ad4add55bedeb5ac9b9ba4cab13da 295 SUPERFAMILY SSF53850 89 292 4.68E-44 T 10-11-2016 A4G23_RS16935 9d7ad4add55bedeb5ac9b9ba4cab13da 295 Gene3D G3DSA:1.10.10.10 1 84 3.1E-30 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS16935 9d7ad4add55bedeb5ac9b9ba4cab13da 295 Pfam PF03466 LysR substrate binding domain 88 289 6.7E-46 T 10-11-2016 IPR005119 LysR, substrate-binding A4G23_RS16935 9d7ad4add55bedeb5ac9b9ba4cab13da 295 Gene3D G3DSA:3.40.190.10 177 259 3.7E-26 T 10-11-2016 A4G23_RS16935 9d7ad4add55bedeb5ac9b9ba4cab13da 295 SUPERFAMILY SSF46785 1 84 6.03E-25 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS16935 9d7ad4add55bedeb5ac9b9ba4cab13da 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.4E-25 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS16935 9d7ad4add55bedeb5ac9b9ba4cab13da 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.3E-11 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS16935 9d7ad4add55bedeb5ac9b9ba4cab13da 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.3E-11 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS16935 9d7ad4add55bedeb5ac9b9ba4cab13da 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.3E-11 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS16935 9d7ad4add55bedeb5ac9b9ba4cab13da 295 Gene3D G3DSA:3.40.190.10 90 176 5.9E-24 T 10-11-2016 A4G23_RS03475 04d93d156009f63da8db8bd22940acd5 480 SUPERFAMILY SSF51412 12 93 5.1E-90 T 10-11-2016 A4G23_RS03475 04d93d156009f63da8db8bd22940acd5 480 SUPERFAMILY SSF51412 215 474 5.1E-90 T 10-11-2016 A4G23_RS03475 04d93d156009f63da8db8bd22940acd5 480 Gene3D G3DSA:3.20.20.70 11 475 4.4E-138 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS03475 04d93d156009f63da8db8bd22940acd5 480 TIGRFAM TIGR01303 IMP_DH_rel_1: IMP dehydrogenase family protein 2 477 2.8E-278 T 10-11-2016 IPR005991 IMP dehydrogenase-related 1 A4G23_RS03475 04d93d156009f63da8db8bd22940acd5 480 SMART SM00116 157 205 0.62 T 10-11-2016 IPR000644 CBS domain A4G23_RS03475 04d93d156009f63da8db8bd22940acd5 480 SMART SM00116 98 146 0.0077 T 10-11-2016 IPR000644 CBS domain A4G23_RS03475 04d93d156009f63da8db8bd22940acd5 480 PIRSF PIRSF000130 2 480 6.3E-148 T 10-11-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 A4G23_RS03475 04d93d156009f63da8db8bd22940acd5 480 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 13 474 9.5E-102 T 10-11-2016 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 A4G23_RS03475 04d93d156009f63da8db8bd22940acd5 480 SMART SM01240 11 475 4.2E-196 T 10-11-2016 A4G23_RS03475 04d93d156009f63da8db8bd22940acd5 480 Pfam PF00571 CBS domain 151 203 6.9E-6 T 10-11-2016 IPR000644 CBS domain A4G23_RS03475 04d93d156009f63da8db8bd22940acd5 480 Pfam PF00571 CBS domain 99 142 4.2E-7 T 10-11-2016 IPR000644 CBS domain A4G23_RS03475 04d93d156009f63da8db8bd22940acd5 480 SUPERFAMILY SSF54631 96 203 4.17E-22 T 10-11-2016 A4G23_RS21780 62a71d59acbb698f0126be5c300174d5 2614 SUPERFAMILY SSF52777 40 224 1.45E-46 T 10-11-2016 A4G23_RS21780 62a71d59acbb698f0126be5c300174d5 2614 Gene3D G3DSA:3.40.50.980 654 793 2.5E-35 T 10-11-2016 A4G23_RS21780 62a71d59acbb698f0126be5c300174d5 2614 Gene3D G3DSA:3.40.50.980 1719 1879 5.9E-29 T 10-11-2016 A4G23_RS21780 62a71d59acbb698f0126be5c300174d5 2614 SMART SM00823 Phosphopantetheine attachment site 2077 2145 0.002 T 10-11-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4G23_RS21780 62a71d59acbb698f0126be5c300174d5 2614 SMART SM00823 Phosphopantetheine attachment site 1000 1069 5.2E-10 T 10-11-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4G23_RS21780 62a71d59acbb698f0126be5c300174d5 2614 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1582 1994 4.4E-115 T 10-11-2016 IPR010071 Amino acid adenylation domain A4G23_RS21780 62a71d59acbb698f0126be5c300174d5 2614 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 526 915 1.8E-122 T 10-11-2016 IPR010071 Amino acid adenylation domain A4G23_RS21780 62a71d59acbb698f0126be5c300174d5 2614 SUPERFAMILY SSF52777 230 468 7.67E-55 T 10-11-2016 A4G23_RS21780 62a71d59acbb698f0126be5c300174d5 2614 SUPERFAMILY SSF52777 2156 2362 4.22E-34 T 10-11-2016 A4G23_RS21780 62a71d59acbb698f0126be5c300174d5 2614 Gene3D G3DSA:3.40.50.980 1559 1718 1.1E-42 T 10-11-2016 A4G23_RS21780 62a71d59acbb698f0126be5c300174d5 2614 Pfam PF00668 Condensation domain 2161 2463 8.7E-50 T 10-11-2016 IPR001242 Condensation domain A4G23_RS21780 62a71d59acbb698f0126be5c300174d5 2614 Pfam PF00668 Condensation domain 1093 1396 3.7E-77 T 10-11-2016 IPR001242 Condensation domain A4G23_RS21780 62a71d59acbb698f0126be5c300174d5 2614 Pfam PF00668 Condensation domain 36 341 1.6E-73 T 10-11-2016 IPR001242 Condensation domain A4G23_RS21780 62a71d59acbb698f0126be5c300174d5 2614 Gene3D G3DSA:3.40.50.980 498 653 3.8E-44 T 10-11-2016 A4G23_RS21780 62a71d59acbb698f0126be5c300174d5 2614 Pfam PF00501 AMP-binding enzyme 506 891 1.4E-89 T 10-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A4G23_RS21780 62a71d59acbb698f0126be5c300174d5 2614 Pfam PF00501 AMP-binding enzyme 1563 1970 3.2E-89 T 10-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A4G23_RS21780 62a71d59acbb698f0126be5c300174d5 2614 Pfam PF13745 HxxPF-repeated domain 1418 1508 5.6E-26 T 10-11-2016 A4G23_RS21780 62a71d59acbb698f0126be5c300174d5 2614 Pfam PF13745 HxxPF-repeated domain 364 455 2.6E-22 T 10-11-2016 A4G23_RS21780 62a71d59acbb698f0126be5c300174d5 2614 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2101 2116 - T 10-11-2016 IPR006162 Phosphopantetheine attachment site A4G23_RS21780 62a71d59acbb698f0126be5c300174d5 2614 SUPERFAMILY SSF47336 993 1065 2.62E-19 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS21780 62a71d59acbb698f0126be5c300174d5 2614 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1712 1723 - T 10-11-2016 IPR020845 AMP-binding, conserved site A4G23_RS21780 62a71d59acbb698f0126be5c300174d5 2614 Pfam PF00550 Phosphopantetheine attachment site 1002 1065 8.2E-14 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS21780 62a71d59acbb698f0126be5c300174d5 2614 Pfam PF00550 Phosphopantetheine attachment site 2079 2139 3.8E-10 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS21780 62a71d59acbb698f0126be5c300174d5 2614 Gene3D G3DSA:3.30.300.30 1965 2080 2.1E-42 T 10-11-2016 A4G23_RS21780 62a71d59acbb698f0126be5c300174d5 2614 Gene3D G3DSA:3.30.300.30 887 1003 7.9E-36 T 10-11-2016 A4G23_RS21780 62a71d59acbb698f0126be5c300174d5 2614 SUPERFAMILY SSF52777 2349 2598 1.33E-43 T 10-11-2016 A4G23_RS21780 62a71d59acbb698f0126be5c300174d5 2614 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 2472 2599 1.1E-24 T 10-11-2016 IPR010060 Non-ribosomal peptide synthase A4G23_RS21780 62a71d59acbb698f0126be5c300174d5 2614 Gene3D G3DSA:2.30.38.10 1881 1960 6.0E-27 T 10-11-2016 A4G23_RS21780 62a71d59acbb698f0126be5c300174d5 2614 Gene3D G3DSA:2.30.38.10 801 881 7.2E-26 T 10-11-2016 A4G23_RS21780 62a71d59acbb698f0126be5c300174d5 2614 ProSitePatterns PS00455 Putative AMP-binding domain signature. 644 655 - T 10-11-2016 IPR020845 AMP-binding, conserved site A4G23_RS21780 62a71d59acbb698f0126be5c300174d5 2614 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1024 1039 - T 10-11-2016 IPR006162 Phosphopantetheine attachment site A4G23_RS21780 62a71d59acbb698f0126be5c300174d5 2614 SUPERFAMILY SSF52777 1088 1298 3.56E-47 T 10-11-2016 A4G23_RS21780 62a71d59acbb698f0126be5c300174d5 2614 SUPERFAMILY SSF47336 2069 2141 7.72E-19 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS21780 62a71d59acbb698f0126be5c300174d5 2614 Pfam PF13193 AMP-binding enzyme C-terminal domain 899 973 7.3E-8 T 10-11-2016 IPR025110 AMP-binding enzyme C-terminal domain A4G23_RS21780 62a71d59acbb698f0126be5c300174d5 2614 Pfam PF13193 AMP-binding enzyme C-terminal domain 1978 2050 1.5E-12 T 10-11-2016 IPR025110 AMP-binding enzyme C-terminal domain A4G23_RS21780 62a71d59acbb698f0126be5c300174d5 2614 SUPERFAMILY SSF56801 495 1013 7.33E-145 T 10-11-2016 A4G23_RS21780 62a71d59acbb698f0126be5c300174d5 2614 Gene3D G3DSA:1.10.1200.10 2081 2143 6.8E-27 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS21780 62a71d59acbb698f0126be5c300174d5 2614 Gene3D G3DSA:1.10.1200.10 1004 1069 1.9E-25 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS21780 62a71d59acbb698f0126be5c300174d5 2614 SUPERFAMILY SSF56801 1526 2090 4.32E-143 T 10-11-2016 A4G23_RS21780 62a71d59acbb698f0126be5c300174d5 2614 SUPERFAMILY SSF52777 1285 1530 1.07E-59 T 10-11-2016 A4G23_RS05160 6010c0c1660739e9356ebf8f2636edb9 422 SUPERFAMILY SSF55174 327 418 7.2E-17 T 10-11-2016 A4G23_RS05160 6010c0c1660739e9356ebf8f2636edb9 422 Gene3D G3DSA:1.10.240.10 234 317 5.2E-40 T 10-11-2016 A4G23_RS05160 6010c0c1660739e9356ebf8f2636edb9 422 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 2 418 4.6E-114 T 10-11-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 A4G23_RS05160 6010c0c1660739e9356ebf8f2636edb9 422 Pfam PF00579 tRNA synthetases class I (W and Y) 30 324 2.5E-80 T 10-11-2016 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4G23_RS05160 6010c0c1660739e9356ebf8f2636edb9 422 SMART SM00363 354 415 2.1E-5 T 10-11-2016 IPR002942 RNA-binding S4 domain GO:0003723 A4G23_RS05160 6010c0c1660739e9356ebf8f2636edb9 422 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 2 419 44.943 T 10-11-2016 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 A4G23_RS05160 6010c0c1660739e9356ebf8f2636edb9 422 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 162 177 1.6E-26 T 10-11-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 A4G23_RS05160 6010c0c1660739e9356ebf8f2636edb9 422 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 183 205 1.6E-26 T 10-11-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 A4G23_RS05160 6010c0c1660739e9356ebf8f2636edb9 422 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 44 66 1.6E-26 T 10-11-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 A4G23_RS05160 6010c0c1660739e9356ebf8f2636edb9 422 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 217 229 1.6E-26 T 10-11-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 A4G23_RS05160 6010c0c1660739e9356ebf8f2636edb9 422 Gene3D G3DSA:3.40.50.620 2 233 3.6E-97 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS05160 6010c0c1660739e9356ebf8f2636edb9 422 SUPERFAMILY SSF52374 3 324 3.2E-101 T 10-11-2016 A4G23_RS05160 6010c0c1660739e9356ebf8f2636edb9 422 Gene3D G3DSA:3.10.290.10 318 419 5.5E-31 T 10-11-2016 IPR002942 RNA-binding S4 domain GO:0003723 A4G23_RS05160 6010c0c1660739e9356ebf8f2636edb9 422 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 40 50 - T 10-11-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4G23_RS02335 3744b7753e5f43cd285197c5b6c890a0 374 Pfam PF07690 Major Facilitator Superfamily 189 369 1.2E-12 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS02335 3744b7753e5f43cd285197c5b6c890a0 374 Gene3D G3DSA:1.20.1250.20 11 159 1.1E-9 T 10-11-2016 A4G23_RS02335 3744b7753e5f43cd285197c5b6c890a0 374 Gene3D G3DSA:1.20.1250.20 173 358 4.3E-21 T 10-11-2016 A4G23_RS02335 3744b7753e5f43cd285197c5b6c890a0 374 SUPERFAMILY SSF103473 2 362 4.19E-35 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS16725 0478ad6403b1f0167bc38c632efc622f 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 9 37 2.0E-9 T 10-11-2016 A4G23_RS16725 0478ad6403b1f0167bc38c632efc622f 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 17.021 T 10-11-2016 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS16725 0478ad6403b1f0167bc38c632efc622f 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 37 9.0E-22 T 10-11-2016 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS16725 0478ad6403b1f0167bc38c632efc622f 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 10-11-2016 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS16725 0478ad6403b1f0167bc38c632efc622f 37 Pfam PF00444 Ribosomal protein L36 1 37 4.2E-18 T 10-11-2016 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS16725 0478ad6403b1f0167bc38c632efc622f 37 SUPERFAMILY SSF57840 1 37 3.53E-16 T 10-11-2016 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS13925 3cdecee55aa7536ca66264415858ed04 257 SUPERFAMILY SSF46689 36 96 3.04E-12 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS13925 3cdecee55aa7536ca66264415858ed04 257 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 102 253 1.4E-13 T 10-11-2016 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 A4G23_RS13925 3cdecee55aa7536ca66264415858ed04 257 Gene3D G3DSA:1.10.357.10 29 256 1.4E-60 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS13925 3cdecee55aa7536ca66264415858ed04 257 Pfam PF00440 Bacterial regulatory proteins, tetR family 43 87 1.8E-9 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS13925 3cdecee55aa7536ca66264415858ed04 257 SUPERFAMILY SSF48498 107 255 8.78E-27 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS05035 271369a923a99006a98b49123c0012a0 186 Pfam PF14279 HNH endonuclease 84 134 6.3E-10 T 10-11-2016 IPR029471 HNH endonuclease 5 A4G23_RS05035 271369a923a99006a98b49123c0012a0 186 SMART SM00507 71 120 1.5E-12 T 10-11-2016 IPR003615 HNH nuclease A4G23_RS03830 19fc66620938e0aec9d1e8c0b5dc0697 137 Pfam PF04686 Streptomyces sporulation and cell division protein, SsgA 23 120 3.5E-38 T 10-11-2016 IPR006776 Sporulation-specific cell division protein SsgB GO:0051301 A4G23_RS26190 263e065fe8c1127c15421b1e894e2708 221 Gene3D G3DSA:3.40.630.30 2 195 2.2E-53 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS26190 263e065fe8c1127c15421b1e894e2708 221 SUPERFAMILY SSF55729 3 179 4.25E-27 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS26190 263e065fe8c1127c15421b1e894e2708 221 Pfam PF13302 Acetyltransferase (GNAT) domain 3 153 4.3E-14 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS25240 ed0d4fd63daca289cf5e0a029e1a6b20 454 Pfam PF02983 Alpha-lytic protease prodomain 132 188 5.6E-18 T 10-11-2016 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 A4G23_RS25240 ed0d4fd63daca289cf5e0a029e1a6b20 454 PIRSF PIRSF001134 2 396 2.1E-150 T 10-11-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A4G23_RS25240 ed0d4fd63daca289cf5e0a029e1a6b20 454 Gene3D G3DSA:2.40.10.10 207 291 1.9E-27 T 10-11-2016 A4G23_RS25240 ed0d4fd63daca289cf5e0a029e1a6b20 454 SUPERFAMILY SSF54806 52 117 9.15E-5 T 10-11-2016 A4G23_RS25240 ed0d4fd63daca289cf5e0a029e1a6b20 454 Gene3D G3DSA:2.10.10.20 410 454 2.2E-22 T 10-11-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 A4G23_RS25240 ed0d4fd63daca289cf5e0a029e1a6b20 454 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 315 332 2.1E-44 T 10-11-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A4G23_RS25240 ed0d4fd63daca289cf5e0a029e1a6b20 454 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 358 372 2.1E-44 T 10-11-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A4G23_RS25240 ed0d4fd63daca289cf5e0a029e1a6b20 454 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 234 248 2.1E-44 T 10-11-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A4G23_RS25240 ed0d4fd63daca289cf5e0a029e1a6b20 454 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 334 357 2.1E-44 T 10-11-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A4G23_RS25240 ed0d4fd63daca289cf5e0a029e1a6b20 454 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 294 314 2.1E-44 T 10-11-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A4G23_RS25240 ed0d4fd63daca289cf5e0a029e1a6b20 454 Gene3D G3DSA:3.30.300.50 47 130 1.2E-29 T 10-11-2016 A4G23_RS25240 ed0d4fd63daca289cf5e0a029e1a6b20 454 Gene3D G3DSA:2.40.10.10 292 380 5.0E-30 T 10-11-2016 A4G23_RS25240 ed0d4fd63daca289cf5e0a029e1a6b20 454 SMART SM00495 408 454 3.7E-13 T 10-11-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 A4G23_RS25240 ed0d4fd63daca289cf5e0a029e1a6b20 454 SUPERFAMILY SSF51055 411 453 1.18E-14 T 10-11-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 A4G23_RS25240 ed0d4fd63daca289cf5e0a029e1a6b20 454 SUPERFAMILY SSF50494 209 388 1.29E-32 T 10-11-2016 IPR009003 Peptidase S1, PA clan A4G23_RS25240 ed0d4fd63daca289cf5e0a029e1a6b20 454 Pfam PF02839 Carbohydrate binding domain 410 451 9.1E-9 T 10-11-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 A4G23_RS25240 ed0d4fd63daca289cf5e0a029e1a6b20 454 Gene3D G3DSA:3.30.300.50 131 200 6.2E-21 T 10-11-2016 A4G23_RS06495 6e395354e6a2854ed0a0bd9b9de0e1f0 347 SUPERFAMILY SSF54001 232 337 7.85E-38 T 10-11-2016 A4G23_RS06495 6e395354e6a2854ed0a0bd9b9de0e1f0 347 Gene3D G3DSA:3.90.1720.10 229 337 7.9E-42 T 10-11-2016 IPR000064 Endopeptidase, NLPC/P60 domain A4G23_RS06495 6e395354e6a2854ed0a0bd9b9de0e1f0 347 Pfam PF00877 NlpC/P60 family 248 335 5.7E-26 T 10-11-2016 IPR000064 Endopeptidase, NLPC/P60 domain A4G23_RS03680 5ce860f55d52e5898f5ac981b12e305c 266 Gene3D G3DSA:2.40.100.10 98 263 3.4E-33 T 10-11-2016 IPR029000 Cyclophilin-like domain A4G23_RS03680 5ce860f55d52e5898f5ac981b12e305c 266 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 102 262 1.8E-26 T 10-11-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 A4G23_RS03680 5ce860f55d52e5898f5ac981b12e305c 266 SUPERFAMILY SSF50891 103 263 1.13E-32 T 10-11-2016 IPR029000 Cyclophilin-like domain A4G23_RS00700 126c5d71d9049a38083f194218778a13 339 SMART SM00354 1 71 6.1E-27 T 10-11-2016 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4G23_RS00700 126c5d71d9049a38083f194218778a13 339 Gene3D G3DSA:3.40.50.2300 54 171 2.7E-26 T 10-11-2016 A4G23_RS00700 126c5d71d9049a38083f194218778a13 339 Gene3D G3DSA:3.40.50.2300 172 312 1.2E-24 T 10-11-2016 A4G23_RS00700 126c5d71d9049a38083f194218778a13 339 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 3.4E-18 T 10-11-2016 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4G23_RS00700 126c5d71d9049a38083f194218778a13 339 SUPERFAMILY SSF53822 58 324 1.09E-36 T 10-11-2016 IPR028082 Periplasmic binding protein-like I A4G23_RS00700 126c5d71d9049a38083f194218778a13 339 SUPERFAMILY SSF47413 1 60 3.66E-17 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS00700 126c5d71d9049a38083f194218778a13 339 Pfam PF13377 Periplasmic binding protein-like domain 168 330 3.2E-28 T 10-11-2016 A4G23_RS00700 126c5d71d9049a38083f194218778a13 339 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 10-11-2016 A4G23_RS00700 126c5d71d9049a38083f194218778a13 339 Gene3D G3DSA:1.10.260.40 2 53 5.5E-24 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS05055 6ce4c1e2e509fdec83a7c3772beb7013 263 SUPERFAMILY SSF52540 4 236 4.7E-50 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05055 6ce4c1e2e509fdec83a7c3772beb7013 263 Pfam PF00005 ABC transporter 21 171 3.3E-27 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS05055 6ce4c1e2e509fdec83a7c3772beb7013 263 SMART SM00382 29 222 8.0E-8 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS05055 6ce4c1e2e509fdec83a7c3772beb7013 263 Gene3D G3DSA:3.40.50.300 6 235 1.0E-50 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS18505 d8d95e6454ee053376c769adc5833e85 364 Pfam PF00155 Aminotransferase class I and II 30 363 7.6E-41 T 10-11-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4G23_RS18505 d8d95e6454ee053376c769adc5833e85 364 TIGRFAM TIGR03539 DapC_actino: succinyldiaminopimelate transaminase 8 363 2.1E-185 T 10-11-2016 IPR019880 Succinyldiaminopimelate transaminase, DapC, actinobacteria A4G23_RS18505 d8d95e6454ee053376c769adc5833e85 364 SUPERFAMILY SSF53383 5 363 2.55E-81 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS18505 d8d95e6454ee053376c769adc5833e85 364 Gene3D G3DSA:3.90.1150.10 242 363 9.1E-23 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS18505 d8d95e6454ee053376c769adc5833e85 364 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 221 234 - T 10-11-2016 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 A4G23_RS18505 d8d95e6454ee053376c769adc5833e85 364 Gene3D G3DSA:3.40.640.10 43 241 8.5E-42 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS05910 5b81d5d164784d327ef1159d92b6af99 475 SUPERFAMILY SSF50800 70 164 1.31E-26 T 10-11-2016 IPR011037 Pyruvate kinase-like, insert domain A4G23_RS05910 5b81d5d164784d327ef1159d92b6af99 475 Gene3D G3DSA:3.40.1380.20 323 470 1.0E-41 T 10-11-2016 IPR015794 Pyruvate kinase, alpha/beta GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4G23_RS05910 5b81d5d164784d327ef1159d92b6af99 475 Pfam PF00224 Pyruvate kinase, barrel domain 1 336 1.0E-120 T 10-11-2016 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4G23_RS05910 5b81d5d164784d327ef1159d92b6af99 475 Gene3D G3DSA:2.40.33.10 73 166 4.4E-29 T 10-11-2016 IPR015806 Pyruvate kinase, beta-barrel insert domain GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4G23_RS05910 5b81d5d164784d327ef1159d92b6af99 475 SUPERFAMILY SSF52935 320 470 2.22E-37 T 10-11-2016 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4G23_RS05910 5b81d5d164784d327ef1159d92b6af99 475 Pfam PF02887 Pyruvate kinase, alpha/beta domain 356 466 2.3E-27 T 10-11-2016 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4G23_RS05910 5b81d5d164784d327ef1159d92b6af99 475 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 2 470 7.1E-159 T 10-11-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4G23_RS05910 5b81d5d164784d327ef1159d92b6af99 475 PRINTS PR01050 Pyruvate kinase family signature 310 326 6.8E-65 T 10-11-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4G23_RS05910 5b81d5d164784d327ef1159d92b6af99 475 PRINTS PR01050 Pyruvate kinase family signature 266 290 6.8E-65 T 10-11-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4G23_RS05910 5b81d5d164784d327ef1159d92b6af99 475 PRINTS PR01050 Pyruvate kinase family signature 214 240 6.8E-65 T 10-11-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4G23_RS05910 5b81d5d164784d327ef1159d92b6af99 475 PRINTS PR01050 Pyruvate kinase family signature 184 198 6.8E-65 T 10-11-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4G23_RS05910 5b81d5d164784d327ef1159d92b6af99 475 PRINTS PR01050 Pyruvate kinase family signature 241 265 6.8E-65 T 10-11-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4G23_RS05910 5b81d5d164784d327ef1159d92b6af99 475 PRINTS PR01050 Pyruvate kinase family signature 291 309 6.8E-65 T 10-11-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4G23_RS05910 5b81d5d164784d327ef1159d92b6af99 475 PRINTS PR01050 Pyruvate kinase family signature 59 75 6.8E-65 T 10-11-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4G23_RS05910 5b81d5d164784d327ef1159d92b6af99 475 SUPERFAMILY SSF51621 1 75 4.54E-97 T 10-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A4G23_RS05910 5b81d5d164784d327ef1159d92b6af99 475 SUPERFAMILY SSF51621 165 336 4.54E-97 T 10-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A4G23_RS05910 5b81d5d164784d327ef1159d92b6af99 475 Gene3D G3DSA:3.20.20.60 167 322 3.5E-101 T 10-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A4G23_RS05910 5b81d5d164784d327ef1159d92b6af99 475 Gene3D G3DSA:3.20.20.60 2 72 3.5E-101 T 10-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A4G23_RS05910 5b81d5d164784d327ef1159d92b6af99 475 ProSitePatterns PS00110 Pyruvate kinase active site signature. 212 224 - T 10-11-2016 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4G23_RS00965 507b2a2ed3cd254091f80eb7925c1602 159 SUPERFAMILY SSF55811 4 153 2.44E-18 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS00965 507b2a2ed3cd254091f80eb7925c1602 159 Gene3D G3DSA:3.90.79.10 3 151 1.1E-26 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS00965 507b2a2ed3cd254091f80eb7925c1602 159 ProSitePatterns PS00893 Nudix box signature. 44 65 - T 10-11-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A4G23_RS00965 507b2a2ed3cd254091f80eb7925c1602 159 Pfam PF00293 NUDIX domain 4 148 7.2E-13 T 10-11-2016 IPR000086 NUDIX hydrolase domain GO:0016787 A4G23_RS15410 d024884df2b546dc9b6958ef41e96bb0 112 Gene3D G3DSA:1.10.10.10 1 68 1.6E-21 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS15410 d024884df2b546dc9b6958ef41e96bb0 112 Pfam PF03965 Penicillinase repressor 1 102 4.2E-20 T 10-11-2016 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 A4G23_RS15410 d024884df2b546dc9b6958ef41e96bb0 112 SUPERFAMILY SSF46785 1 103 1.88E-21 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS20720 e830524bd72a5cc1acde205434bfa111 78 Gene3D G3DSA:3.30.70.20 4 68 1.0E-9 T 10-11-2016 A4G23_RS20720 e830524bd72a5cc1acde205434bfa111 78 SUPERFAMILY SSF54862 3 65 3.64E-9 T 10-11-2016 A4G23_RS20720 e830524bd72a5cc1acde205434bfa111 78 Pfam PF13459 4Fe-4S single cluster domain 6 64 3.9E-9 T 10-11-2016 A4G23_RS20720 e830524bd72a5cc1acde205434bfa111 78 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 2.3E-6 T 10-11-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A4G23_RS20720 e830524bd72a5cc1acde205434bfa111 78 PRINTS PR00352 3Fe-4S ferredoxin signature 51 63 2.3E-6 T 10-11-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A4G23_RS20720 e830524bd72a5cc1acde205434bfa111 78 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 2.3E-6 T 10-11-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A4G23_RS13015 9166a8f4746c4efa2db887cf1c9f5c72 250 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 2 208 1.2E-40 T 10-11-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A4G23_RS13015 9166a8f4746c4efa2db887cf1c9f5c72 250 Gene3D G3DSA:3.40.1010.10 2 110 4.3E-36 T 10-11-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A4G23_RS13015 9166a8f4746c4efa2db887cf1c9f5c72 250 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 6 20 - T 10-11-2016 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 A4G23_RS13015 9166a8f4746c4efa2db887cf1c9f5c72 250 SUPERFAMILY SSF53790 2 233 2.36E-62 T 10-11-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A4G23_RS13015 9166a8f4746c4efa2db887cf1c9f5c72 250 Gene3D G3DSA:3.30.950.10 111 232 1.1E-32 T 10-11-2016 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A4G23_RS13015 9166a8f4746c4efa2db887cf1c9f5c72 250 TIGRFAM TIGR01465 cobM_cbiF: precorrin-4 C11-methyltransferase 3 244 2.9E-90 T 10-11-2016 IPR006362 Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase GO:0009236|GO:0046026 A4G23_RS13015 9166a8f4746c4efa2db887cf1c9f5c72 250 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 76 109 - T 10-11-2016 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 A4G23_RS25760 662c285f3bbe6c20c7ec83a82b283013 194 SUPERFAMILY SSF88659 94 172 1.4E-13 T 10-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS25760 662c285f3bbe6c20c7ec83a82b283013 194 SUPERFAMILY SSF88946 10 96 7.85E-18 T 10-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS25760 662c285f3bbe6c20c7ec83a82b283013 194 Gene3D G3DSA:1.10.10.10 113 173 2.6E-16 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS25760 662c285f3bbe6c20c7ec83a82b283013 194 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 42 74 - T 10-11-2016 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS25760 662c285f3bbe6c20c7ec83a82b283013 194 Pfam PF04542 Sigma-70 region 2 20 86 6.6E-15 T 10-11-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS25760 662c285f3bbe6c20c7ec83a82b283013 194 Gene3D G3DSA:1.10.1740.10 9 88 1.5E-19 T 10-11-2016 A4G23_RS25760 662c285f3bbe6c20c7ec83a82b283013 194 Pfam PF04545 Sigma-70, region 4 121 167 8.5E-12 T 10-11-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS25760 662c285f3bbe6c20c7ec83a82b283013 194 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 16 170 1.9E-21 T 10-11-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS10390 f5818b1714ad89eb1af4d9e6c77b6d2d 234 Pfam PF06737 Transglycosylase-like domain 41 117 1.7E-35 T 10-11-2016 IPR010618 Transglycosylase-like A4G23_RS10390 f5818b1714ad89eb1af4d9e6c77b6d2d 234 Gene3D G3DSA:3.10.350.10 187 233 9.4E-10 T 10-11-2016 IPR018392 LysM domain A4G23_RS10390 f5818b1714ad89eb1af4d9e6c77b6d2d 234 Gene3D G3DSA:1.10.530.10 21 121 5.4E-43 T 10-11-2016 A4G23_RS10390 f5818b1714ad89eb1af4d9e6c77b6d2d 234 SUPERFAMILY SSF53955 42 119 2.81E-32 T 10-11-2016 IPR023346 Lysozyme-like domain A4G23_RS10390 f5818b1714ad89eb1af4d9e6c77b6d2d 234 Pfam PF01476 LysM domain 187 233 5.0E-8 T 10-11-2016 IPR018392 LysM domain A4G23_RS10390 f5818b1714ad89eb1af4d9e6c77b6d2d 234 SUPERFAMILY SSF54106 186 233 1.24E-5 T 10-11-2016 IPR018392 LysM domain A4G23_RS10390 f5818b1714ad89eb1af4d9e6c77b6d2d 234 SMART SM00257 186 234 7.2E-7 T 10-11-2016 IPR018392 LysM domain A4G23_RS23670 4b73251d274319452e4624b6de3ae24c 289 SUPERFAMILY SSF52402 160 288 1.84E-19 T 10-11-2016 A4G23_RS23670 4b73251d274319452e4624b6de3ae24c 289 Pfam PF00582 Universal stress protein family 2 136 2.3E-24 T 10-11-2016 IPR006016 UspA GO:0006950 A4G23_RS23670 4b73251d274319452e4624b6de3ae24c 289 Pfam PF00582 Universal stress protein family 160 287 3.0E-14 T 10-11-2016 IPR006016 UspA GO:0006950 A4G23_RS23670 4b73251d274319452e4624b6de3ae24c 289 PRINTS PR01438 Universal stress protein signature 2 20 1.4E-7 T 10-11-2016 IPR006015 Universal stress protein A A4G23_RS23670 4b73251d274319452e4624b6de3ae24c 289 PRINTS PR01438 Universal stress protein signature 96 108 1.4E-7 T 10-11-2016 IPR006015 Universal stress protein A A4G23_RS23670 4b73251d274319452e4624b6de3ae24c 289 PRINTS PR01438 Universal stress protein signature 114 136 1.4E-7 T 10-11-2016 IPR006015 Universal stress protein A A4G23_RS23670 4b73251d274319452e4624b6de3ae24c 289 SUPERFAMILY SSF52402 4 140 2.51E-28 T 10-11-2016 A4G23_RS23670 4b73251d274319452e4624b6de3ae24c 289 Gene3D G3DSA:3.40.50.620 158 287 2.9E-21 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS23670 4b73251d274319452e4624b6de3ae24c 289 Gene3D G3DSA:3.40.50.620 1 136 1.3E-29 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS24800 e13bceeb8571a088acc6fe95a0a7b4b9 503 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 304 319 2.9E-38 T 10-11-2016 A4G23_RS24800 e13bceeb8571a088acc6fe95a0a7b4b9 503 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 319 335 2.9E-38 T 10-11-2016 A4G23_RS24800 e13bceeb8571a088acc6fe95a0a7b4b9 503 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 37 59 2.9E-38 T 10-11-2016 A4G23_RS24800 e13bceeb8571a088acc6fe95a0a7b4b9 503 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 181 196 2.9E-38 T 10-11-2016 A4G23_RS24800 e13bceeb8571a088acc6fe95a0a7b4b9 503 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 357 373 2.9E-38 T 10-11-2016 A4G23_RS24800 e13bceeb8571a088acc6fe95a0a7b4b9 503 Pfam PF01494 FAD binding domain 35 371 3.4E-87 T 10-11-2016 IPR002938 FAD-binding domain GO:0071949 A4G23_RS24800 e13bceeb8571a088acc6fe95a0a7b4b9 503 SUPERFAMILY SSF51905 36 202 4.32E-67 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS24800 e13bceeb8571a088acc6fe95a0a7b4b9 503 SUPERFAMILY SSF51905 300 418 4.32E-67 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS24800 e13bceeb8571a088acc6fe95a0a7b4b9 503 Gene3D G3DSA:3.50.50.60 292 375 3.2E-59 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS24800 e13bceeb8571a088acc6fe95a0a7b4b9 503 Gene3D G3DSA:3.50.50.60 36 207 3.2E-59 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS15480 8b08344b80e15c3c82a3c25b29c8e80b 373 Gene3D G3DSA:3.40.1700.10 30 153 2.0E-30 T 10-11-2016 A4G23_RS15480 8b08344b80e15c3c82a3c25b29c8e80b 373 SUPERFAMILY SSF47781 296 365 4.82E-13 T 10-11-2016 IPR010994 RuvA domain 2-like A4G23_RS15480 8b08344b80e15c3c82a3c25b29c8e80b 373 Gene3D G3DSA:1.10.150.20 310 360 5.5E-12 T 10-11-2016 A4G23_RS15480 8b08344b80e15c3c82a3c25b29c8e80b 373 SUPERFAMILY SSF143597 31 152 1.05E-26 T 10-11-2016 A4G23_RS15480 8b08344b80e15c3c82a3c25b29c8e80b 373 Pfam PF12826 Helix-hairpin-helix motif 323 360 1.1E-6 T 10-11-2016 A4G23_RS15480 8b08344b80e15c3c82a3c25b29c8e80b 373 Hamap MF_01438 DNA integrity scanning protein DisA [disA]. 21 370 43.994 T 10-11-2016 IPR023763 DNA integrity scanning protein, DisA A4G23_RS15480 8b08344b80e15c3c82a3c25b29c8e80b 373 Pfam PF10635 DisA bacterial checkpoint controller linker region 154 296 2.0E-52 T 10-11-2016 IPR018906 DNA integrity scanning, DisA, linker region A4G23_RS15480 8b08344b80e15c3c82a3c25b29c8e80b 373 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 37 150 4.3E-23 T 10-11-2016 IPR003390 DNA integrity scanning protein, DisA, N-terminal A4G23_RS01365 b6213ef3025e8cbc585fc02e1d6b3025 416 Pfam PF01569 PAP2 superfamily 279 410 2.1E-8 T 10-11-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A4G23_RS01365 b6213ef3025e8cbc585fc02e1d6b3025 416 Gene3D G3DSA:1.10.606.10 155 414 4.8E-61 T 10-11-2016 IPR016119 Bromoperoxidase/chloroperoxidase, C-terminal GO:0004601|GO:0055114 A4G23_RS01365 b6213ef3025e8cbc585fc02e1d6b3025 416 SUPERFAMILY SSF48317 58 412 1.7E-56 T 10-11-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A4G23_RS01365 b6213ef3025e8cbc585fc02e1d6b3025 416 Gene3D G3DSA:1.20.144.10 62 154 1.3E-14 T 10-11-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A4G23_RS22445 03f736c473bac50e8a5c22c501a7a4ac 593 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 412 422 - T 10-11-2016 IPR023828 Peptidase S8, subtilisin, Ser-active site A4G23_RS22445 03f736c473bac50e8a5c22c501a7a4ac 593 Gene3D G3DSA:3.40.50.200 131 469 5.1E-88 T 10-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4G23_RS22445 03f736c473bac50e8a5c22c501a7a4ac 593 SUPERFAMILY SSF49785 486 593 3.57E-22 T 10-11-2016 IPR008979 Galactose-binding domain-like A4G23_RS22445 03f736c473bac50e8a5c22c501a7a4ac 593 SUPERFAMILY SSF52743 113 192 8.64E-74 T 10-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4G23_RS22445 03f736c473bac50e8a5c22c501a7a4ac 593 SUPERFAMILY SSF52743 220 469 8.64E-74 T 10-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4G23_RS22445 03f736c473bac50e8a5c22c501a7a4ac 593 Gene3D G3DSA:3.30.70.80 42 130 3.1E-4 T 10-11-2016 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 A4G23_RS22445 03f736c473bac50e8a5c22c501a7a4ac 593 Pfam PF00082 Subtilase family 163 461 1.7E-49 T 10-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4G23_RS22445 03f736c473bac50e8a5c22c501a7a4ac 593 Pfam PF01483 Proprotein convertase P-domain 513 593 8.5E-19 T 10-11-2016 IPR002884 Proprotein convertase, P GO:0004252|GO:0006508 A4G23_RS22445 03f736c473bac50e8a5c22c501a7a4ac 593 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 234 244 - T 10-11-2016 IPR022398 Peptidase S8, subtilisin, His-active site A4G23_RS22445 03f736c473bac50e8a5c22c501a7a4ac 593 Gene3D G3DSA:2.60.120.260 491 593 3.9E-16 T 10-11-2016 IPR008979 Galactose-binding domain-like A4G23_RS22445 03f736c473bac50e8a5c22c501a7a4ac 593 PRINTS PR00723 Subtilisin serine protease family (S8) signature 230 243 1.1E-16 T 10-11-2016 IPR015500 Peptidase S8, subtilisin-related A4G23_RS22445 03f736c473bac50e8a5c22c501a7a4ac 593 PRINTS PR00723 Subtilisin serine protease family (S8) signature 411 427 1.1E-16 T 10-11-2016 IPR015500 Peptidase S8, subtilisin-related A4G23_RS22445 03f736c473bac50e8a5c22c501a7a4ac 593 PRINTS PR00723 Subtilisin serine protease family (S8) signature 163 182 1.1E-16 T 10-11-2016 IPR015500 Peptidase S8, subtilisin-related A4G23_RS26580 13c13b87f0d00895995b46b67cf31367 508 Gene3D G3DSA:2.60.40.10 364 442 3.8E-17 T 10-11-2016 IPR013783 Immunoglobulin-like fold A4G23_RS26580 13c13b87f0d00895995b46b67cf31367 508 SUPERFAMILY SSF49265 361 448 3.65E-14 T 10-11-2016 IPR003961 Fibronectin type III GO:0005515 A4G23_RS26580 13c13b87f0d00895995b46b67cf31367 508 TIGRFAM TIGR01840 esterase_phb: esterase, PHB depolymerase family 75 285 5.0E-70 T 10-11-2016 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 A4G23_RS26580 13c13b87f0d00895995b46b67cf31367 508 SUPERFAMILY SSF53474 65 317 8.73E-38 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS26580 13c13b87f0d00895995b46b67cf31367 508 Gene3D G3DSA:3.40.50.1820 29 336 1.1E-51 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS26580 13c13b87f0d00895995b46b67cf31367 508 Pfam PF10503 Esterase PHB depolymerase 78 279 3.4E-40 T 10-11-2016 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 A4G23_RS26580 13c13b87f0d00895995b46b67cf31367 508 SMART SM00060 362 432 4.3E-8 T 10-11-2016 IPR003961 Fibronectin type III GO:0005515 A4G23_RS14990 b0e5b68a243c4a723d0a7a5eff51dd61 250 SMART SM00422 3 82 7.8E-13 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS14990 b0e5b68a243c4a723d0a7a5eff51dd61 250 Pfam PF00376 MerR family regulatory protein 4 41 9.3E-12 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS14990 b0e5b68a243c4a723d0a7a5eff51dd61 250 SUPERFAMILY SSF46955 4 106 3.22E-20 T 10-11-2016 IPR009061 Putative DNA-binding domain A4G23_RS14990 b0e5b68a243c4a723d0a7a5eff51dd61 250 Gene3D G3DSA:1.10.1660.10 4 108 3.0E-23 T 10-11-2016 A4G23_RS24045 1bd3aeb90a0fff9789c2fca967e39b20 522 SUPERFAMILY SSF103473 7 203 2.49E-60 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS24045 1bd3aeb90a0fff9789c2fca967e39b20 522 SUPERFAMILY SSF103473 471 496 2.49E-60 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS24045 1bd3aeb90a0fff9789c2fca967e39b20 522 SUPERFAMILY SSF103473 250 421 2.49E-60 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS24045 1bd3aeb90a0fff9789c2fca967e39b20 522 Gene3D G3DSA:1.20.1250.20 472 497 2.8E-15 T 10-11-2016 A4G23_RS24045 1bd3aeb90a0fff9789c2fca967e39b20 522 Gene3D G3DSA:1.20.1250.20 259 422 2.8E-15 T 10-11-2016 A4G23_RS24045 1bd3aeb90a0fff9789c2fca967e39b20 522 Gene3D G3DSA:1.20.1250.20 14 198 1.1E-26 T 10-11-2016 A4G23_RS24045 1bd3aeb90a0fff9789c2fca967e39b20 522 PRINTS PR01035 Tetracycline resistance protein signature 331 354 9.3E-7 T 10-11-2016 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4G23_RS24045 1bd3aeb90a0fff9789c2fca967e39b20 522 PRINTS PR01035 Tetracycline resistance protein signature 29 45 9.3E-7 T 10-11-2016 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4G23_RS24045 1bd3aeb90a0fff9789c2fca967e39b20 522 PRINTS PR01035 Tetracycline resistance protein signature 142 164 9.3E-7 T 10-11-2016 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4G23_RS24045 1bd3aeb90a0fff9789c2fca967e39b20 522 PRINTS PR01035 Tetracycline resistance protein signature 59 78 9.3E-7 T 10-11-2016 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4G23_RS24045 1bd3aeb90a0fff9789c2fca967e39b20 522 Pfam PF07690 Major Facilitator Superfamily 24 411 2.0E-40 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS06695 9993ac0d1c64f1298d58caf7ef9734c8 626 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 10-11-2016 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 A4G23_RS06695 9993ac0d1c64f1298d58caf7ef9734c8 626 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 390 617 8.7E-72 T 10-11-2016 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A4G23_RS06695 9993ac0d1c64f1298d58caf7ef9734c8 626 TIGRFAM TIGR02927 SucB_Actino: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase 271 626 8.7E-135 T 10-11-2016 IPR014276 2-oxoglutarate dehydrogenase, E2 component KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12 A4G23_RS06695 9993ac0d1c64f1298d58caf7ef9734c8 626 Gene3D G3DSA:3.30.559.10 379 617 7.3E-78 T 10-11-2016 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 A4G23_RS06695 9993ac0d1c64f1298d58caf7ef9734c8 626 Gene3D G3DSA:4.10.320.10 317 366 1.1E-18 T 10-11-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A4G23_RS06695 9993ac0d1c64f1298d58caf7ef9734c8 626 PRINTS PR01217 Proline rich extensin signature 231 247 1.5E-10 T 10-11-2016 A4G23_RS06695 9993ac0d1c64f1298d58caf7ef9734c8 626 PRINTS PR01217 Proline rich extensin signature 251 268 1.5E-10 T 10-11-2016 A4G23_RS06695 9993ac0d1c64f1298d58caf7ef9734c8 626 PRINTS PR01217 Proline rich extensin signature 115 131 1.5E-10 T 10-11-2016 A4G23_RS06695 9993ac0d1c64f1298d58caf7ef9734c8 626 PRINTS PR01217 Proline rich extensin signature 273 298 1.5E-10 T 10-11-2016 A4G23_RS06695 9993ac0d1c64f1298d58caf7ef9734c8 626 SUPERFAMILY SSF52777 376 617 5.34E-77 T 10-11-2016 A4G23_RS06695 9993ac0d1c64f1298d58caf7ef9734c8 626 SUPERFAMILY SSF47005 315 359 8.37E-12 T 10-11-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A4G23_RS06695 9993ac0d1c64f1298d58caf7ef9734c8 626 SUPERFAMILY SSF51230 2 95 1.03E-26 T 10-11-2016 IPR011053 Single hybrid motif A4G23_RS06695 9993ac0d1c64f1298d58caf7ef9734c8 626 Gene3D G3DSA:2.40.50.100 147 239 1.7E-29 T 10-11-2016 A4G23_RS06695 9993ac0d1c64f1298d58caf7ef9734c8 626 Gene3D G3DSA:2.40.50.100 2 96 9.2E-30 T 10-11-2016 A4G23_RS06695 9993ac0d1c64f1298d58caf7ef9734c8 626 SUPERFAMILY SSF51230 147 240 1.31E-26 T 10-11-2016 IPR011053 Single hybrid motif A4G23_RS06695 9993ac0d1c64f1298d58caf7ef9734c8 626 Pfam PF00364 Biotin-requiring enzyme 148 220 1.2E-19 T 10-11-2016 IPR000089 Biotin/lipoyl attachment A4G23_RS06695 9993ac0d1c64f1298d58caf7ef9734c8 626 Pfam PF00364 Biotin-requiring enzyme 5 76 1.9E-21 T 10-11-2016 IPR000089 Biotin/lipoyl attachment A4G23_RS06695 9993ac0d1c64f1298d58caf7ef9734c8 626 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 171 200 - T 10-11-2016 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 A4G23_RS06695 9993ac0d1c64f1298d58caf7ef9734c8 626 Pfam PF02817 e3 binding domain 322 355 1.2E-13 T 10-11-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A4G23_RS10885 341d74d1ac7b726a03cdeb5590238fa2 303 Gene3D G3DSA:3.90.550.10 10 282 2.0E-72 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS10885 341d74d1ac7b726a03cdeb5590238fa2 303 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 8 273 2.2E-101 T 10-11-2016 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343 A4G23_RS10885 341d74d1ac7b726a03cdeb5590238fa2 303 SUPERFAMILY SSF53448 10 291 5.2E-63 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS10885 341d74d1ac7b726a03cdeb5590238fa2 303 Pfam PF00483 Nucleotidyl transferase 10 273 1.2E-26 T 10-11-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A4G23_RS14420 ccaf398dc3878669285d71e279fdf0e1 219 Gene3D G3DSA:3.90.20.20 47 137 1.1E-20 T 10-11-2016 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 A4G23_RS14420 ccaf398dc3878669285d71e279fdf0e1 219 Gene3D G3DSA:2.30.22.10 138 195 3.9E-22 T 10-11-2016 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 A4G23_RS14420 ccaf398dc3878669285d71e279fdf0e1 219 SUPERFAMILY SSF51064 140 195 4.84E-16 T 10-11-2016 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 A4G23_RS14420 ccaf398dc3878669285d71e279fdf0e1 219 Pfam PF01025 GrpE 42 194 1.6E-36 T 10-11-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A4G23_RS14420 ccaf398dc3878669285d71e279fdf0e1 219 PRINTS PR00773 GrpE protein signature 99 114 6.9E-25 T 10-11-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A4G23_RS14420 ccaf398dc3878669285d71e279fdf0e1 219 PRINTS PR00773 GrpE protein signature 173 192 6.9E-25 T 10-11-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A4G23_RS14420 ccaf398dc3878669285d71e279fdf0e1 219 PRINTS PR00773 GrpE protein signature 71 87 6.9E-25 T 10-11-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A4G23_RS14420 ccaf398dc3878669285d71e279fdf0e1 219 PRINTS PR00773 GrpE protein signature 146 161 6.9E-25 T 10-11-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A4G23_RS14420 ccaf398dc3878669285d71e279fdf0e1 219 Hamap MF_01151 Protein GrpE [grpE]. 3 194 17.489 T 10-11-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A4G23_RS14420 ccaf398dc3878669285d71e279fdf0e1 219 ProSitePatterns PS01071 grpE protein signature. 149 192 - T 10-11-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A4G23_RS14420 ccaf398dc3878669285d71e279fdf0e1 219 SUPERFAMILY SSF58014 53 138 3.27E-18 T 10-11-2016 A4G23_RS16020 db30d191852806a0760d14104d1d767d 179 Pfam PF13302 Acetyltransferase (GNAT) domain 19 157 2.1E-23 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS16020 db30d191852806a0760d14104d1d767d 179 SUPERFAMILY SSF55729 15 158 1.08E-29 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS16020 db30d191852806a0760d14104d1d767d 179 Gene3D G3DSA:3.40.630.30 16 167 1.7E-33 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS13720 fe81a17a35b206dd95076e7f7b83b634 1214 SUPERFAMILY SSF90123 639 955 1.96E-40 T 10-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A4G23_RS13720 fe81a17a35b206dd95076e7f7b83b634 1214 SUPERFAMILY SSF52540 327 544 2.31E-63 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS13720 fe81a17a35b206dd95076e7f7b83b634 1214 ProSitePatterns PS00211 ABC transporters family signature. 471 485 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS13720 fe81a17a35b206dd95076e7f7b83b634 1214 SMART SM00382 360 545 3.6E-17 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS13720 fe81a17a35b206dd95076e7f7b83b634 1214 SMART SM00382 995 1181 5.7E-14 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS13720 fe81a17a35b206dd95076e7f7b83b634 1214 Pfam PF00664 ABC transporter transmembrane region 653 904 4.2E-6 T 10-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A4G23_RS13720 fe81a17a35b206dd95076e7f7b83b634 1214 Pfam PF00664 ABC transporter transmembrane region 20 270 1.5E-28 T 10-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A4G23_RS13720 fe81a17a35b206dd95076e7f7b83b634 1214 ProSitePatterns PS00211 ABC transporters family signature. 1107 1121 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS13720 fe81a17a35b206dd95076e7f7b83b634 1214 Gene3D G3DSA:1.20.1560.10 6 322 8.2E-48 T 10-11-2016 A4G23_RS13720 fe81a17a35b206dd95076e7f7b83b634 1214 Gene3D G3DSA:1.20.1560.10 639 955 2.9E-32 T 10-11-2016 A4G23_RS13720 fe81a17a35b206dd95076e7f7b83b634 1214 SUPERFAMILY SSF52540 966 1202 4.09E-68 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS13720 fe81a17a35b206dd95076e7f7b83b634 1214 Pfam PF00005 ABC transporter 988 1134 1.5E-26 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS13720 fe81a17a35b206dd95076e7f7b83b634 1214 Pfam PF00005 ABC transporter 351 499 8.6E-30 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS13720 fe81a17a35b206dd95076e7f7b83b634 1214 Gene3D G3DSA:3.40.50.300 334 544 7.1E-63 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS13720 fe81a17a35b206dd95076e7f7b83b634 1214 Gene3D G3DSA:3.40.50.300 969 1196 4.4E-63 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS13720 fe81a17a35b206dd95076e7f7b83b634 1214 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 638 1165 1.1E-195 T 10-11-2016 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0006810|GO:0016021|GO:0042626 A4G23_RS13720 fe81a17a35b206dd95076e7f7b83b634 1214 SUPERFAMILY SSF90123 2 322 4.84E-56 T 10-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A4G23_RS13720 fe81a17a35b206dd95076e7f7b83b634 1214 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 17 541 1.8E-210 T 10-11-2016 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 A4G23_RS18955 cc26071dfbcf1f559a5ec25fc68437cd 216 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 47 203 6.6E-37 T 10-11-2016 IPR023635 Peptide deformylase A4G23_RS18955 cc26071dfbcf1f559a5ec25fc68437cd 216 PRINTS PR01576 Peptide deformylase signature 71 100 1.7E-31 T 10-11-2016 IPR023635 Peptide deformylase A4G23_RS18955 cc26071dfbcf1f559a5ec25fc68437cd 216 PRINTS PR01576 Peptide deformylase signature 164 193 1.7E-31 T 10-11-2016 IPR023635 Peptide deformylase A4G23_RS18955 cc26071dfbcf1f559a5ec25fc68437cd 216 PRINTS PR01576 Peptide deformylase signature 145 163 1.7E-31 T 10-11-2016 IPR023635 Peptide deformylase A4G23_RS18955 cc26071dfbcf1f559a5ec25fc68437cd 216 PRINTS PR01576 Peptide deformylase signature 133 144 1.7E-31 T 10-11-2016 IPR023635 Peptide deformylase A4G23_RS18955 cc26071dfbcf1f559a5ec25fc68437cd 216 Gene3D G3DSA:3.90.45.10 42 205 1.5E-55 T 10-11-2016 IPR023635 Peptide deformylase A4G23_RS18955 cc26071dfbcf1f559a5ec25fc68437cd 216 SUPERFAMILY SSF56420 40 203 1.83E-52 T 10-11-2016 IPR023635 Peptide deformylase A4G23_RS18955 cc26071dfbcf1f559a5ec25fc68437cd 216 Hamap MF_00163 Peptide deformylase [def]. 40 206 27.707 T 10-11-2016 IPR023635 Peptide deformylase A4G23_RS18955 cc26071dfbcf1f559a5ec25fc68437cd 216 Pfam PF01327 Polypeptide deformylase 42 196 7.2E-44 T 10-11-2016 IPR023635 Peptide deformylase A4G23_RS27260 098b0779d2718dce95faafc5f799b7fe 391 SUPERFAMILY SSF51569 8 296 5.49E-74 T 10-11-2016 A4G23_RS27260 098b0779d2718dce95faafc5f799b7fe 391 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 205 218 - T 10-11-2016 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A4G23_RS27260 098b0779d2718dce95faafc5f799b7fe 391 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 20 36 - T 10-11-2016 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A4G23_RS27260 098b0779d2718dce95faafc5f799b7fe 391 Gene3D G3DSA:3.20.20.70 5 351 2.2E-103 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS27260 098b0779d2718dce95faafc5f799b7fe 391 Pfam PF00682 HMGL-like 13 275 4.2E-69 T 10-11-2016 IPR000891 Pyruvate carboxyltransferase GO:0003824 A4G23_RS06715 dcd1ba02a264cdb3e165b0445e504a0b 315 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 103 114 6.2E-8 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS06715 dcd1ba02a264cdb3e165b0445e504a0b 315 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 173 6.2E-8 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS06715 dcd1ba02a264cdb3e165b0445e504a0b 315 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 204 6.2E-8 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS06715 dcd1ba02a264cdb3e165b0445e504a0b 315 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 18 35 6.2E-8 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS06715 dcd1ba02a264cdb3e165b0445e504a0b 315 SUPERFAMILY SSF51735 13 274 3.15E-33 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS06715 dcd1ba02a264cdb3e165b0445e504a0b 315 Gene3D G3DSA:3.40.50.720 14 275 1.4E-37 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS06715 dcd1ba02a264cdb3e165b0445e504a0b 315 Pfam PF00106 short chain dehydrogenase 18 221 9.0E-13 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS07045 deab0607cd4f84c6133afd270c4eed7a 122 SUPERFAMILY SSF101386 43 120 1.36E-9 T 10-11-2016 A4G23_RS07045 deab0607cd4f84c6133afd270c4eed7a 122 Gene3D G3DSA:1.10.287.1080 49 96 8.6E-5 T 10-11-2016 A4G23_RS03225 0c9b1ed798ad24ff1fe63ef646275876 130 SMART SM00248 44 73 0.0012 T 10-11-2016 IPR002110 Ankyrin repeat GO:0005515 A4G23_RS03225 0c9b1ed798ad24ff1fe63ef646275876 130 SMART SM00248 77 106 0.21 T 10-11-2016 IPR002110 Ankyrin repeat GO:0005515 A4G23_RS03225 0c9b1ed798ad24ff1fe63ef646275876 130 Pfam PF12796 Ankyrin repeats (3 copies) 21 105 8.5E-10 T 10-11-2016 IPR020683 Ankyrin repeat-containing domain A4G23_RS03225 0c9b1ed798ad24ff1fe63ef646275876 130 SUPERFAMILY SSF48403 16 127 8.55E-22 T 10-11-2016 IPR020683 Ankyrin repeat-containing domain A4G23_RS03225 0c9b1ed798ad24ff1fe63ef646275876 130 Gene3D G3DSA:1.25.40.20 15 125 5.2E-22 T 10-11-2016 IPR020683 Ankyrin repeat-containing domain A4G23_RS08755 070822f4ab4ff6e08c65c518ad7ae449 743 Gene3D G3DSA:3.40.50.300 647 711 1.2E-18 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS08755 070822f4ab4ff6e08c65c518ad7ae449 743 SUPERFAMILY SSF52540 446 513 2.48E-55 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS08755 070822f4ab4ff6e08c65c518ad7ae449 743 SUPERFAMILY SSF52540 554 722 2.48E-55 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS08755 070822f4ab4ff6e08c65c518ad7ae449 743 SUPERFAMILY SSF47781 85 162 9.14E-10 T 10-11-2016 IPR010994 RuvA domain 2-like A4G23_RS08755 070822f4ab4ff6e08c65c518ad7ae449 743 Pfam PF14520 Helix-hairpin-helix domain 94 138 4.0E-6 T 10-11-2016 A4G23_RS08755 070822f4ab4ff6e08c65c518ad7ae449 743 Gene3D G3DSA:3.40.50.300 311 513 5.0E-43 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS08755 070822f4ab4ff6e08c65c518ad7ae449 743 Hamap MF_01488 ATP-dependent RecD-like DNA helicase [recD2]. 4 742 28.851 T 10-11-2016 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 A4G23_RS08755 070822f4ab4ff6e08c65c518ad7ae449 743 Pfam PF14490 Helix-hairpin-helix containing domain 144 234 5.1E-30 T 10-11-2016 IPR029493 RecD helicase-like helix-hairpin-helix domain A4G23_RS08755 070822f4ab4ff6e08c65c518ad7ae449 743 Pfam PF13538 UvrD-like helicase C-terminal domain 659 707 2.3E-19 T 10-11-2016 IPR027785 UvrD-like helicase C-terminal domain A4G23_RS08755 070822f4ab4ff6e08c65c518ad7ae449 743 TIGRFAM TIGR01448 recD_rel: helicase, RecD/TraA family 8 732 5.1E-197 T 10-11-2016 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 A4G23_RS08755 070822f4ab4ff6e08c65c518ad7ae449 743 Gene3D G3DSA:1.10.150.20 94 162 8.4E-4 T 10-11-2016 A4G23_RS08755 070822f4ab4ff6e08c65c518ad7ae449 743 SUPERFAMILY SSF52540 333 484 2.67E-43 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS08755 070822f4ab4ff6e08c65c518ad7ae449 743 SUPERFAMILY SSF52540 184 298 2.67E-43 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS08755 070822f4ab4ff6e08c65c518ad7ae449 743 Pfam PF13604 AAA domain 337 515 5.5E-44 T 10-11-2016 A4G23_RS03430 dac891bb522520b75cc0bf289be626a3 490 PIRSF PIRSF006060 37 488 2.3E-93 T 10-11-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A4G23_RS03430 dac891bb522520b75cc0bf289be626a3 490 TIGRFAM TIGR00909 2A0306: amino acid transporter 48 478 5.7E-174 T 10-11-2016 IPR004758 Amino acid transporter A4G23_RS03430 dac891bb522520b75cc0bf289be626a3 490 Pfam PF13520 Amino acid permease 52 453 1.1E-56 T 10-11-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A4G23_RS23515 3cdd1e9d8fe9f5034eded5d2699921c2 512 Gene3D G3DSA:3.40.50.720 3 232 4.7E-43 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS23515 3cdd1e9d8fe9f5034eded5d2699921c2 512 Pfam PF13460 NAD(P)H-binding 6 149 6.6E-23 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS23515 3cdd1e9d8fe9f5034eded5d2699921c2 512 SUPERFAMILY SSF55961 338 487 5.18E-8 T 10-11-2016 A4G23_RS23515 3cdd1e9d8fe9f5034eded5d2699921c2 512 SUPERFAMILY SSF51735 3 243 2.31E-52 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS23515 3cdd1e9d8fe9f5034eded5d2699921c2 512 Pfam PF11066 Protein of unknown function (DUF2867) 331 476 1.9E-41 T 10-11-2016 IPR021295 Protein of unknown function DUF2867 A4G23_RS20060 5ce06fc8b5fe04d129eb5eb7a6a3c06a 734 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 640 709 1.1E-13 T 10-11-2016 IPR001357 BRCT domain A4G23_RS20060 5ce06fc8b5fe04d129eb5eb7a6a3c06a 734 Gene3D G3DSA:3.30.470.30 130 262 8.8E-51 T 10-11-2016 A4G23_RS20060 5ce06fc8b5fe04d129eb5eb7a6a3c06a 734 SUPERFAMILY SSF52113 639 716 6.17E-18 T 10-11-2016 IPR001357 BRCT domain A4G23_RS20060 5ce06fc8b5fe04d129eb5eb7a6a3c06a 734 Gene3D G3DSA:1.10.150.20 446 548 1.9E-8 T 10-11-2016 A4G23_RS20060 5ce06fc8b5fe04d129eb5eb7a6a3c06a 734 PIRSF PIRSF001604 7 718 1.5E-241 T 10-11-2016 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 A4G23_RS20060 5ce06fc8b5fe04d129eb5eb7a6a3c06a 734 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 341 356 - T 10-11-2016 IPR033136 NAD-dependent DNA ligase, conserved site A4G23_RS20060 5ce06fc8b5fe04d129eb5eb7a6a3c06a 734 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 417 445 2.6E-8 T 10-11-2016 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 A4G23_RS20060 5ce06fc8b5fe04d129eb5eb7a6a3c06a 734 Gene3D G3DSA:3.40.50.10190 640 717 3.1E-24 T 10-11-2016 IPR001357 BRCT domain A4G23_RS20060 5ce06fc8b5fe04d129eb5eb7a6a3c06a 734 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 23 502 3.2E-172 T 10-11-2016 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 A4G23_RS20060 5ce06fc8b5fe04d129eb5eb7a6a3c06a 734 SUPERFAMILY SSF56091 14 328 1.37E-110 T 10-11-2016 A4G23_RS20060 5ce06fc8b5fe04d129eb5eb7a6a3c06a 734 SMART SM00292 640 717 1.2E-11 T 10-11-2016 IPR001357 BRCT domain A4G23_RS20060 5ce06fc8b5fe04d129eb5eb7a6a3c06a 734 SMART SM00532 15 459 1.2E-257 T 10-11-2016 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 A4G23_RS20060 5ce06fc8b5fe04d129eb5eb7a6a3c06a 734 Pfam PF12826 Helix-hairpin-helix motif 556 619 7.2E-22 T 10-11-2016 A4G23_RS20060 5ce06fc8b5fe04d129eb5eb7a6a3c06a 734 Gene3D G3DSA:1.10.287.610 8 77 2.9E-25 T 10-11-2016 A4G23_RS20060 5ce06fc8b5fe04d129eb5eb7a6a3c06a 734 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 126 155 - T 10-11-2016 IPR018239 NAD-dependent DNA ligase, active site A4G23_RS20060 5ce06fc8b5fe04d129eb5eb7a6a3c06a 734 SUPERFAMILY SSF50249 328 410 1.11E-24 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS20060 5ce06fc8b5fe04d129eb5eb7a6a3c06a 734 SUPERFAMILY SSF47781 413 506 1.37E-47 T 10-11-2016 IPR010994 RuvA domain 2-like A4G23_RS20060 5ce06fc8b5fe04d129eb5eb7a6a3c06a 734 SUPERFAMILY SSF47781 537 630 1.37E-47 T 10-11-2016 IPR010994 RuvA domain 2-like A4G23_RS20060 5ce06fc8b5fe04d129eb5eb7a6a3c06a 734 Gene3D G3DSA:2.40.50.140 330 400 2.4E-27 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS20060 5ce06fc8b5fe04d129eb5eb7a6a3c06a 734 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 15 328 1.7E-121 T 10-11-2016 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 A4G23_RS20060 5ce06fc8b5fe04d129eb5eb7a6a3c06a 734 Gene3D G3DSA:1.10.150.20 550 631 4.1E-29 T 10-11-2016 A4G23_RS20060 5ce06fc8b5fe04d129eb5eb7a6a3c06a 734 Hamap MF_01588 DNA ligase [ligA]. 14 714 50.706 T 10-11-2016 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 A4G23_RS20060 5ce06fc8b5fe04d129eb5eb7a6a3c06a 734 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 332 407 6.8E-29 T 10-11-2016 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 A4G23_RS24920 c921667433116f066ddf6b45c87e29b8 340 Gene3D G3DSA:3.20.20.70 23 310 2.5E-38 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS24920 c921667433116f066ddf6b45c87e29b8 340 Pfam PF11946 Domain of unknown function (DUF3463) 196 328 2.6E-56 T 10-11-2016 IPR022563 Domain of unknown function DUF3463 A4G23_RS24920 c921667433116f066ddf6b45c87e29b8 340 TIGRFAM TIGR03470 HpnH: hopanoid biosynthesis associated radical SAM protein HpnH 1 318 1.9E-163 T 10-11-2016 IPR017833 Hopanoid biosynthesis associated radical SAM protein HpnH A4G23_RS24920 c921667433116f066ddf6b45c87e29b8 340 Pfam PF04055 Radical SAM superfamily 34 187 1.5E-15 T 10-11-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 A4G23_RS24920 c921667433116f066ddf6b45c87e29b8 340 SUPERFAMILY SSF102114 24 308 9.22E-47 T 10-11-2016 A4G23_RS08490 6489d309f532a5b1fbf907a62fafc903 422 Gene3D G3DSA:3.90.110.10 162 419 1.4E-85 T 10-11-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 A4G23_RS08490 6489d309f532a5b1fbf907a62fafc903 422 SUPERFAMILY SSF56327 165 419 2.33E-61 T 10-11-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 A4G23_RS08490 6489d309f532a5b1fbf907a62fafc903 422 Gene3D G3DSA:3.40.50.720 1 158 4.2E-56 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS08490 6489d309f532a5b1fbf907a62fafc903 422 PRINTS PR00732 Glycosyl hydrolase family 4 signature 92 105 3.4E-35 T 10-11-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A4G23_RS08490 6489d309f532a5b1fbf907a62fafc903 422 PRINTS PR00732 Glycosyl hydrolase family 4 signature 2 17 3.4E-35 T 10-11-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A4G23_RS08490 6489d309f532a5b1fbf907a62fafc903 422 PRINTS PR00732 Glycosyl hydrolase family 4 signature 71 87 3.4E-35 T 10-11-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A4G23_RS08490 6489d309f532a5b1fbf907a62fafc903 422 PRINTS PR00732 Glycosyl hydrolase family 4 signature 135 152 3.4E-35 T 10-11-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A4G23_RS08490 6489d309f532a5b1fbf907a62fafc903 422 PRINTS PR00732 Glycosyl hydrolase family 4 signature 106 126 3.4E-35 T 10-11-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A4G23_RS08490 6489d309f532a5b1fbf907a62fafc903 422 PRINTS PR00732 Glycosyl hydrolase family 4 signature 185 197 3.4E-35 T 10-11-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A4G23_RS08490 6489d309f532a5b1fbf907a62fafc903 422 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 190 398 8.2E-42 T 10-11-2016 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 A4G23_RS08490 6489d309f532a5b1fbf907a62fafc903 422 Pfam PF02056 Family 4 glycosyl hydrolase 2 178 2.7E-45 T 10-11-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A4G23_RS08490 6489d309f532a5b1fbf907a62fafc903 422 SUPERFAMILY SSF51735 1 156 2.12E-44 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS16340 244f4115c393150a102b1da76abf0382 299 ProSitePatterns PS01014 Transcription termination factor nusG signature. 282 291 - T 10-11-2016 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site A4G23_RS16340 244f4115c393150a102b1da76abf0382 299 Gene3D G3DSA:2.30.30.30 244 298 2.1E-25 T 10-11-2016 IPR014722 Ribosomal protein L2 domain 2 A4G23_RS16340 244f4115c393150a102b1da76abf0382 299 SUPERFAMILY SSF50104 244 298 5.21E-15 T 10-11-2016 IPR008991 Translation protein SH3-like domain A4G23_RS16340 244f4115c393150a102b1da76abf0382 299 PRINTS PR00338 Transcription termination factor NUSG signature 275 291 4.6E-18 T 10-11-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 A4G23_RS16340 244f4115c393150a102b1da76abf0382 299 PRINTS PR00338 Transcription termination factor NUSG signature 257 272 4.6E-18 T 10-11-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 A4G23_RS16340 244f4115c393150a102b1da76abf0382 299 PRINTS PR00338 Transcription termination factor NUSG signature 164 176 4.6E-18 T 10-11-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 A4G23_RS16340 244f4115c393150a102b1da76abf0382 299 SUPERFAMILY SSF82679 111 217 4.45E-34 T 10-11-2016 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A4G23_RS16340 244f4115c393150a102b1da76abf0382 299 SMART SM00739 245 272 3.5E-4 T 10-11-2016 IPR005824 KOW A4G23_RS16340 244f4115c393150a102b1da76abf0382 299 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 112 298 1.1E-53 T 10-11-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 A4G23_RS16340 244f4115c393150a102b1da76abf0382 299 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 109 299 22.617 T 10-11-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 A4G23_RS16340 244f4115c393150a102b1da76abf0382 299 Gene3D G3DSA:3.30.70.940 111 219 8.6E-41 T 10-11-2016 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A4G23_RS16340 244f4115c393150a102b1da76abf0382 299 Pfam PF02357 Transcription termination factor nusG 111 213 4.5E-22 T 10-11-2016 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A4G23_RS16340 244f4115c393150a102b1da76abf0382 299 SMART SM00738 109 217 2.7E-48 T 10-11-2016 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A4G23_RS23880 3b3f43fc008c27f165bc879dca874179 322 SUPERFAMILY SSF56112 50 289 2.33E-27 T 10-11-2016 IPR011009 Protein kinase-like domain A4G23_RS23880 3b3f43fc008c27f165bc879dca874179 322 Pfam PF04655 Aminoglycoside/hydroxyurea antibiotic resistance kinase 42 289 1.5E-74 T 10-11-2016 IPR006748 Aminoglycoside/hydroxyurea antibiotic resistance kinase GO:0006468|GO:0016773|GO:0019748 A4G23_RS23880 3b3f43fc008c27f165bc879dca874179 322 Gene3D G3DSA:3.90.1200.10 124 245 7.1E-4 T 10-11-2016 A4G23_RS01465 db2c4db1ed352440f9d17af88e0522c0 457 SUPERFAMILY SSF56601 72 394 6.44E-65 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS01465 db2c4db1ed352440f9d17af88e0522c0 457 Pfam PF00144 Beta-lactamase 81 392 1.6E-53 T 10-11-2016 IPR001466 Beta-lactamase-related A4G23_RS01465 db2c4db1ed352440f9d17af88e0522c0 457 Gene3D G3DSA:3.40.710.10 63 393 1.3E-66 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS04040 4ae938d4ea0c9d0eb247b3d933d4a5b4 570 Gene3D G3DSA:2.30.40.10 5 65 8.0E-19 T 10-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4G23_RS04040 4ae938d4ea0c9d0eb247b3d933d4a5b4 570 Gene3D G3DSA:2.30.40.10 533 566 8.0E-19 T 10-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4G23_RS04040 4ae938d4ea0c9d0eb247b3d933d4a5b4 570 SUPERFAMILY SSF51338 3 64 9.47E-25 T 10-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4G23_RS04040 4ae938d4ea0c9d0eb247b3d933d4a5b4 570 SUPERFAMILY SSF51338 524 567 9.47E-25 T 10-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4G23_RS04040 4ae938d4ea0c9d0eb247b3d933d4a5b4 570 Gene3D G3DSA:2.30.40.10 507 532 1.6E-4 T 10-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4G23_RS04040 4ae938d4ea0c9d0eb247b3d933d4a5b4 570 Pfam PF07969 Amidohydrolase family 52 565 3.7E-89 T 10-11-2016 IPR013108 Amidohydrolase 3 A4G23_RS04040 4ae938d4ea0c9d0eb247b3d933d4a5b4 570 SUPERFAMILY SSF51556 63 124 2.44E-24 T 10-11-2016 IPR032466 Metal-dependent hydrolase A4G23_RS04040 4ae938d4ea0c9d0eb247b3d933d4a5b4 570 SUPERFAMILY SSF51556 205 525 2.44E-24 T 10-11-2016 IPR032466 Metal-dependent hydrolase A4G23_RS04040 4ae938d4ea0c9d0eb247b3d933d4a5b4 570 Gene3D G3DSA:3.20.20.140 67 85 2.2E-23 T 10-11-2016 A4G23_RS04040 4ae938d4ea0c9d0eb247b3d933d4a5b4 570 Gene3D G3DSA:3.20.20.140 211 506 2.2E-23 T 10-11-2016 A4G23_RS21860 a41540985b41e9b2e0046644a11ee110 411 Gene3D G3DSA:1.10.630.10 5 406 1.1E-111 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS21860 a41540985b41e9b2e0046644a11ee110 411 PRINTS PR00385 P450 superfamily signature 269 280 1.6E-5 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS21860 a41540985b41e9b2e0046644a11ee110 411 PRINTS PR00385 P450 superfamily signature 345 354 1.6E-5 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS21860 a41540985b41e9b2e0046644a11ee110 411 PRINTS PR00385 P450 superfamily signature 234 251 1.6E-5 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS21860 a41540985b41e9b2e0046644a11ee110 411 PRINTS PR00385 P450 superfamily signature 354 365 1.6E-5 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS21860 a41540985b41e9b2e0046644a11ee110 411 Pfam PF00067 Cytochrome P450 33 143 1.8E-6 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS21860 a41540985b41e9b2e0046644a11ee110 411 Pfam PF00067 Cytochrome P450 181 372 2.8E-30 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS21860 a41540985b41e9b2e0046644a11ee110 411 SUPERFAMILY SSF48264 12 405 5.89E-93 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS21860 a41540985b41e9b2e0046644a11ee110 411 PRINTS PR00359 B-class P450 signature 354 365 8.8E-38 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS21860 a41540985b41e9b2e0046644a11ee110 411 PRINTS PR00359 B-class P450 signature 144 159 8.8E-38 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS21860 a41540985b41e9b2e0046644a11ee110 411 PRINTS PR00359 B-class P450 signature 286 313 8.8E-38 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS21860 a41540985b41e9b2e0046644a11ee110 411 PRINTS PR00359 B-class P450 signature 188 210 8.8E-38 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS21860 a41540985b41e9b2e0046644a11ee110 411 PRINTS PR00359 B-class P450 signature 269 280 8.8E-38 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS21860 a41540985b41e9b2e0046644a11ee110 411 PRINTS PR00359 B-class P450 signature 127 143 8.8E-38 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS21860 a41540985b41e9b2e0046644a11ee110 411 PRINTS PR00359 B-class P450 signature 314 329 8.8E-38 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS21860 a41540985b41e9b2e0046644a11ee110 411 PRINTS PR00359 B-class P450 signature 345 354 8.8E-38 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS05340 81cd4096850f6192046e5b737592456e 366 Gene3D G3DSA:3.20.20.140 57 327 6.5E-62 T 10-11-2016 A4G23_RS05340 81cd4096850f6192046e5b737592456e 366 Gene3D G3DSA:2.30.40.10 7 56 4.4E-9 T 10-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4G23_RS05340 81cd4096850f6192046e5b737592456e 366 Gene3D G3DSA:2.30.40.10 328 365 4.4E-9 T 10-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4G23_RS05340 81cd4096850f6192046e5b737592456e 366 SUPERFAMILY SSF51338 5 64 7.46E-5 T 10-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4G23_RS05340 81cd4096850f6192046e5b737592456e 366 Pfam PF01979 Amidohydrolase family 52 365 7.1E-16 T 10-11-2016 IPR006680 Amidohydrolase-related GO:0016787 A4G23_RS05340 81cd4096850f6192046e5b737592456e 366 SUPERFAMILY SSF51556 55 328 8.17E-60 T 10-11-2016 IPR032466 Metal-dependent hydrolase A4G23_RS05340 81cd4096850f6192046e5b737592456e 366 SUPERFAMILY SSF51338 310 365 2.72E-6 T 10-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4G23_RS16655 76388a1b3151578e5213a29bd888a8fd 122 Gene3D G3DSA:2.40.150.20 2 122 2.5E-53 T 10-11-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 A4G23_RS16655 76388a1b3151578e5213a29bd888a8fd 122 Pfam PF00238 Ribosomal protein L14p/L23e 2 122 1.2E-53 T 10-11-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 A4G23_RS16655 76388a1b3151578e5213a29bd888a8fd 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 27.175 T 10-11-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 A4G23_RS16655 76388a1b3151578e5213a29bd888a8fd 122 SUPERFAMILY SSF50193 2 122 4.84E-50 T 10-11-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 A4G23_RS16655 76388a1b3151578e5213a29bd888a8fd 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 10-11-2016 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS16655 76388a1b3151578e5213a29bd888a8fd 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 4.2E-57 T 10-11-2016 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 A4G23_RS16655 76388a1b3151578e5213a29bd888a8fd 122 SMART SM01374 1 122 1.2E-86 T 10-11-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 A4G23_RS18690 32a5f73f3ac28ec6d95341a90b3493ea 464 SUPERFAMILY SSF53756 116 429 2.32E-48 T 10-11-2016 A4G23_RS18690 32a5f73f3ac28ec6d95341a90b3493ea 464 Pfam PF11997 Domain of unknown function (DUF3492) 5 207 4.3E-12 T 10-11-2016 IPR022622 Domain of unknown function DUF3492 A4G23_RS18690 32a5f73f3ac28ec6d95341a90b3493ea 464 Pfam PF13692 Glycosyl transferases group 1 235 393 2.1E-19 T 10-11-2016 A4G23_RS18690 32a5f73f3ac28ec6d95341a90b3493ea 464 Gene3D G3DSA:3.40.50.2000 228 406 7.0E-17 T 10-11-2016 A4G23_RS23580 a495622e31d47ff78b6e9861f7cc0468 793 Gene3D G3DSA:2.70.98.40 3 262 2.1E-79 T 10-11-2016 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 A4G23_RS23580 a495622e31d47ff78b6e9861f7cc0468 793 Pfam PF03633 Glycosyl hydrolase family 65, C-terminal domain 730 779 7.4E-8 T 10-11-2016 IPR005194 Glycoside hydrolase family 65, C-terminal A4G23_RS23580 a495622e31d47ff78b6e9861f7cc0468 793 SUPERFAMILY SSF48208 268 772 3.91E-98 T 10-11-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 A4G23_RS23580 a495622e31d47ff78b6e9861f7cc0468 793 PIRSF PIRSF036289 1 793 1.2E-208 T 10-11-2016 IPR017045 Maltose phosphorylase/glycosyl hydrolase/vacuolar acid trehalase A4G23_RS23580 a495622e31d47ff78b6e9861f7cc0468 793 Gene3D G3DSA:1.50.10.10 308 710 1.2E-125 T 10-11-2016 IPR012341 Six-hairpin glycosidase GO:0003824 A4G23_RS23580 a495622e31d47ff78b6e9861f7cc0468 793 Pfam PF03632 Glycosyl hydrolase family 65 central catalytic domain 312 724 1.0E-145 T 10-11-2016 IPR005195 Glycoside hydrolase, family 65, central catalytic GO:0003824|GO:0005975 A4G23_RS23580 a495622e31d47ff78b6e9861f7cc0468 793 SUPERFAMILY SSF74650 3 261 2.54E-57 T 10-11-2016 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 A4G23_RS23580 a495622e31d47ff78b6e9861f7cc0468 793 Pfam PF03636 Glycosyl hydrolase family 65, N-terminal domain 9 260 1.3E-63 T 10-11-2016 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 A4G23_RS23580 a495622e31d47ff78b6e9861f7cc0468 793 Gene3D G3DSA:2.60.420.10 712 783 5.7E-4 T 10-11-2016 A4G23_RS05745 c640ba31d837f59bec8d5720b4d114ec 722 Pfam PF02151 UvrB/uvrC motif 680 712 4.0E-7 T 10-11-2016 IPR001943 UVR domain GO:0005515 A4G23_RS05745 c640ba31d837f59bec8d5720b4d114ec 722 SMART SM00487 18 433 2.0E-26 T 10-11-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4G23_RS05745 c640ba31d837f59bec8d5720b4d114ec 722 Hamap MF_00204 UvrABC system protein B [uvrB]. 12 712 42.358 T 10-11-2016 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 A4G23_RS05745 c640ba31d837f59bec8d5720b4d114ec 722 SUPERFAMILY SSF46600 673 715 2.48E-9 T 10-11-2016 IPR001943 UVR domain GO:0005515 A4G23_RS05745 c640ba31d837f59bec8d5720b4d114ec 722 Pfam PF04851 Type III restriction enzyme, res subunit 25 134 1.2E-8 T 10-11-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 A4G23_RS05745 c640ba31d837f59bec8d5720b4d114ec 722 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 14 710 0.0 T 10-11-2016 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 A4G23_RS05745 c640ba31d837f59bec8d5720b4d114ec 722 Pfam PF12344 Ultra-violet resistance protein B 559 600 4.6E-20 T 10-11-2016 IPR024759 UvrB, YAD/RRR-motif-containing domain A4G23_RS05745 c640ba31d837f59bec8d5720b4d114ec 722 Gene3D G3DSA:4.10.860.10 670 716 1.4E-12 T 10-11-2016 IPR001943 UVR domain GO:0005515 A4G23_RS05745 c640ba31d837f59bec8d5720b4d114ec 722 Gene3D G3DSA:3.40.50.300 426 588 8.8E-38 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05745 c640ba31d837f59bec8d5720b4d114ec 722 SMART SM00490 467 553 2.3E-18 T 10-11-2016 IPR001650 Helicase, C-terminal A4G23_RS05745 c640ba31d837f59bec8d5720b4d114ec 722 Pfam PF00271 Helicase conserved C-terminal domain 442 552 4.8E-19 T 10-11-2016 IPR001650 Helicase, C-terminal A4G23_RS05745 c640ba31d837f59bec8d5720b4d114ec 722 Gene3D G3DSA:3.30.2060.10 168 237 2.5E-11 T 10-11-2016 A4G23_RS05745 c640ba31d837f59bec8d5720b4d114ec 722 SUPERFAMILY SSF52540 42 91 3.11E-35 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05745 c640ba31d837f59bec8d5720b4d114ec 722 SUPERFAMILY SSF52540 466 588 3.11E-35 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05745 c640ba31d837f59bec8d5720b4d114ec 722 Gene3D G3DSA:3.40.50.300 15 98 3.2E-49 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05745 c640ba31d837f59bec8d5720b4d114ec 722 Gene3D G3DSA:3.40.50.300 286 346 3.2E-49 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05745 c640ba31d837f59bec8d5720b4d114ec 722 Gene3D G3DSA:3.40.50.300 396 417 3.2E-49 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05745 c640ba31d837f59bec8d5720b4d114ec 722 SUPERFAMILY SSF52540 13 422 2.58E-135 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS16860 1399ceabacbace16c34d639d689f1210 394 PRINTS PR00992 Alanine racemase signature 80 98 1.4E-61 T 10-11-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4G23_RS16860 1399ceabacbace16c34d639d689f1210 394 PRINTS PR00992 Alanine racemase signature 296 311 1.4E-61 T 10-11-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4G23_RS16860 1399ceabacbace16c34d639d689f1210 394 PRINTS PR00992 Alanine racemase signature 178 189 1.4E-61 T 10-11-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4G23_RS16860 1399ceabacbace16c34d639d689f1210 394 PRINTS PR00992 Alanine racemase signature 141 153 1.4E-61 T 10-11-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4G23_RS16860 1399ceabacbace16c34d639d689f1210 394 PRINTS PR00992 Alanine racemase signature 372 385 1.4E-61 T 10-11-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4G23_RS16860 1399ceabacbace16c34d639d689f1210 394 PRINTS PR00992 Alanine racemase signature 317 334 1.4E-61 T 10-11-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4G23_RS16860 1399ceabacbace16c34d639d689f1210 394 PRINTS PR00992 Alanine racemase signature 44 60 1.4E-61 T 10-11-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4G23_RS16860 1399ceabacbace16c34d639d689f1210 394 PRINTS PR00992 Alanine racemase signature 221 248 1.4E-61 T 10-11-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4G23_RS16860 1399ceabacbace16c34d639d689f1210 394 PRINTS PR00992 Alanine racemase signature 279 294 1.4E-61 T 10-11-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4G23_RS16860 1399ceabacbace16c34d639d689f1210 394 Pfam PF01168 Alanine racemase, N-terminal domain 24 248 2.9E-67 T 10-11-2016 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4G23_RS16860 1399ceabacbace16c34d639d689f1210 394 SMART SM01005 263 390 1.8E-63 T 10-11-2016 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4G23_RS16860 1399ceabacbace16c34d639d689f1210 394 Gene3D G3DSA:2.40.37.10 242 392 3.2E-57 T 10-11-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A4G23_RS16860 1399ceabacbace16c34d639d689f1210 394 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 49 59 - T 10-11-2016 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4G23_RS16860 1399ceabacbace16c34d639d689f1210 394 SUPERFAMILY SSF50621 256 391 9.07E-47 T 10-11-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A4G23_RS16860 1399ceabacbace16c34d639d689f1210 394 TIGRFAM TIGR00492 alr: alanine racemase 20 390 9.8E-93 T 10-11-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4G23_RS16860 1399ceabacbace16c34d639d689f1210 394 Hamap MF_01201 Alanine racemase. 17 390 32.544 T 10-11-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4G23_RS16860 1399ceabacbace16c34d639d689f1210 394 Pfam PF00842 Alanine racemase, C-terminal domain 263 388 6.0E-38 T 10-11-2016 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4G23_RS16860 1399ceabacbace16c34d639d689f1210 394 SUPERFAMILY SSF51419 24 264 5.52E-66 T 10-11-2016 IPR029066 PLP-binding barrel A4G23_RS16860 1399ceabacbace16c34d639d689f1210 394 Gene3D G3DSA:3.20.20.10 26 241 1.3E-72 T 10-11-2016 IPR029066 PLP-binding barrel A4G23_RS16745 14749788f162db8d88e9d74dadb315c8 164 Pfam PF01196 Ribosomal protein L17 20 116 1.4E-37 T 10-11-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS16745 14749788f162db8d88e9d74dadb315c8 164 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 27.005 T 10-11-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS16745 14749788f162db8d88e9d74dadb315c8 164 SUPERFAMILY SSF64263 1 118 7.33E-47 T 10-11-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS16745 14749788f162db8d88e9d74dadb315c8 164 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 10-11-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS16745 14749788f162db8d88e9d74dadb315c8 164 Gene3D G3DSA:3.90.1030.10 3 117 5.2E-46 T 10-11-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS16745 14749788f162db8d88e9d74dadb315c8 164 TIGRFAM TIGR00059 L17: ribosomal protein bL17 9 117 2.4E-41 T 10-11-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS03405 2639a622cf71c492a15cd5e38523b697 413 Gene3D G3DSA:1.20.1250.20 10 181 2.9E-18 T 10-11-2016 A4G23_RS03405 2639a622cf71c492a15cd5e38523b697 413 Pfam PF07690 Major Facilitator Superfamily 227 373 1.2E-9 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS03405 2639a622cf71c492a15cd5e38523b697 413 Pfam PF07690 Major Facilitator Superfamily 16 204 1.8E-14 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS03405 2639a622cf71c492a15cd5e38523b697 413 SUPERFAMILY SSF103473 9 384 3.53E-41 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS03405 2639a622cf71c492a15cd5e38523b697 413 Gene3D G3DSA:1.20.1250.20 205 380 1.3E-13 T 10-11-2016 A4G23_RS13160 99ec6811efd8eb4777bb920cc5a0cefc 326 SMART SM00861 6 181 3.2E-68 T 10-11-2016 IPR005475 Transketolase-like, pyrimidine-binding domain A4G23_RS13160 99ec6811efd8eb4777bb920cc5a0cefc 326 Gene3D G3DSA:3.40.50.970 4 194 1.1E-73 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS13160 99ec6811efd8eb4777bb920cc5a0cefc 326 Gene3D G3DSA:3.40.50.920 198 320 3.2E-45 T 10-11-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 A4G23_RS13160 99ec6811efd8eb4777bb920cc5a0cefc 326 Pfam PF02779 Transketolase, pyrimidine binding domain 5 179 8.9E-46 T 10-11-2016 IPR005475 Transketolase-like, pyrimidine-binding domain A4G23_RS13160 99ec6811efd8eb4777bb920cc5a0cefc 326 Pfam PF02780 Transketolase, C-terminal domain 196 315 3.0E-41 T 10-11-2016 IPR033248 Transketolase, C-terminal domain A4G23_RS13160 99ec6811efd8eb4777bb920cc5a0cefc 326 SUPERFAMILY SSF52518 5 185 1.47E-66 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS13160 99ec6811efd8eb4777bb920cc5a0cefc 326 SUPERFAMILY SSF52922 193 324 1.7E-40 T 10-11-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 A4G23_RS04375 41fb5880183b9a43b7574ca832902d76 253 ProSitePatterns PS00221 MIP family signature. 65 73 - T 10-11-2016 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 A4G23_RS04375 41fb5880183b9a43b7574ca832902d76 253 PRINTS PR00783 Major intrinsic protein family signature 5 24 7.7E-45 T 10-11-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 A4G23_RS04375 41fb5880183b9a43b7574ca832902d76 253 PRINTS PR00783 Major intrinsic protein family signature 230 250 7.7E-45 T 10-11-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 A4G23_RS04375 41fb5880183b9a43b7574ca832902d76 253 PRINTS PR00783 Major intrinsic protein family signature 47 71 7.7E-45 T 10-11-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 A4G23_RS04375 41fb5880183b9a43b7574ca832902d76 253 PRINTS PR00783 Major intrinsic protein family signature 183 205 7.7E-45 T 10-11-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 A4G23_RS04375 41fb5880183b9a43b7574ca832902d76 253 PRINTS PR00783 Major intrinsic protein family signature 83 102 7.7E-45 T 10-11-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 A4G23_RS04375 41fb5880183b9a43b7574ca832902d76 253 PRINTS PR00783 Major intrinsic protein family signature 150 168 7.7E-45 T 10-11-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 A4G23_RS04375 41fb5880183b9a43b7574ca832902d76 253 TIGRFAM TIGR00861 MIP: MIP family channel proteins 10 247 3.8E-54 T 10-11-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 A4G23_RS04375 41fb5880183b9a43b7574ca832902d76 253 SUPERFAMILY SSF81338 7 251 1.01E-64 T 10-11-2016 IPR023271 Aquaporin-like Reactome: R-HSA-432047 A4G23_RS04375 41fb5880183b9a43b7574ca832902d76 253 Gene3D G3DSA:1.20.1080.10 6 250 4.4E-82 T 10-11-2016 IPR023271 Aquaporin-like Reactome: R-HSA-432047 A4G23_RS04375 41fb5880183b9a43b7574ca832902d76 253 Pfam PF00230 Major intrinsic protein 6 247 5.4E-43 T 10-11-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 A4G23_RS18500 eb6b8815aeea1556ee01a752bdaf9428 106 SUPERFAMILY SSF54862 3 92 5.03E-22 T 10-11-2016 A4G23_RS18500 eb6b8815aeea1556ee01a752bdaf9428 106 Gene3D G3DSA:3.30.70.20 3 77 8.6E-20 T 10-11-2016 A4G23_RS18500 eb6b8815aeea1556ee01a752bdaf9428 106 Pfam PF00037 4Fe-4S binding domain 34 55 1.2E-8 T 10-11-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4G23_RS18500 eb6b8815aeea1556ee01a752bdaf9428 106 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 10-11-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4G23_RS18500 eb6b8815aeea1556ee01a752bdaf9428 106 PRINTS PR00354 7Fe ferredoxin signature 35 52 3.9E-18 T 10-11-2016 IPR000813 7Fe ferredoxin GO:0009055 A4G23_RS18500 eb6b8815aeea1556ee01a752bdaf9428 106 PRINTS PR00354 7Fe ferredoxin signature 19 29 3.9E-18 T 10-11-2016 IPR000813 7Fe ferredoxin GO:0009055 A4G23_RS18500 eb6b8815aeea1556ee01a752bdaf9428 106 PRINTS PR00354 7Fe ferredoxin signature 9 19 3.9E-18 T 10-11-2016 IPR000813 7Fe ferredoxin GO:0009055 A4G23_RS11130 513c7373da499232e6b473991c848079 366 Pfam PF01032 FecCD transport family 41 358 1.5E-96 T 10-11-2016 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 A4G23_RS11130 513c7373da499232e6b473991c848079 366 Gene3D G3DSA:1.10.3470.10 28 362 2.3E-108 T 10-11-2016 IPR029022 ABC transporter, BtuC-like A4G23_RS11130 513c7373da499232e6b473991c848079 366 SUPERFAMILY SSF81345 26 360 1.96E-82 T 10-11-2016 IPR029022 ABC transporter, BtuC-like A4G23_RS20180 ef55f0679055f303751110535fa46a6c 560 Pfam PF00449 Urease alpha-subunit, N-terminal domain 4 117 1.9E-37 T 10-11-2016 IPR011612 Urease alpha-subunit, N-terminal domain KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4G23_RS20180 ef55f0679055f303751110535fa46a6c 560 SUPERFAMILY SSF51338 2 127 2.06E-40 T 10-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4G23_RS20180 ef55f0679055f303751110535fa46a6c 560 SUPERFAMILY SSF51338 417 463 2.06E-40 T 10-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4G23_RS20180 ef55f0679055f303751110535fa46a6c 560 Pfam PF01979 Amidohydrolase family 123 444 5.9E-43 T 10-11-2016 IPR006680 Amidohydrolase-related GO:0016787 A4G23_RS20180 ef55f0679055f303751110535fa46a6c 560 Hamap MF_01953 Urease subunit alpha [ureC]. 1 560 45.73 T 10-11-2016 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4G23_RS20180 ef55f0679055f303751110535fa46a6c 560 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 396 411 7.5E-24 T 10-11-2016 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4G23_RS20180 ef55f0679055f303751110535fa46a6c 560 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 329 345 7.5E-24 T 10-11-2016 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4G23_RS20180 ef55f0679055f303751110535fa46a6c 560 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 290 307 7.5E-24 T 10-11-2016 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4G23_RS20180 ef55f0679055f303751110535fa46a6c 560 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 422 435 7.5E-24 T 10-11-2016 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4G23_RS20180 ef55f0679055f303751110535fa46a6c 560 SUPERFAMILY SSF51556 127 427 1.67E-140 T 10-11-2016 IPR032466 Metal-dependent hydrolase A4G23_RS20180 ef55f0679055f303751110535fa46a6c 560 SUPERFAMILY SSF51556 476 560 1.67E-140 T 10-11-2016 IPR032466 Metal-dependent hydrolase A4G23_RS20180 ef55f0679055f303751110535fa46a6c 560 ProSitePatterns PS01120 Urease nickel ligands signature. 125 138 - T 10-11-2016 IPR029754 Urease nickel binding site GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4G23_RS20180 ef55f0679055f303751110535fa46a6c 560 Gene3D G3DSA:2.30.40.10 1 140 6.4E-43 T 10-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4G23_RS20180 ef55f0679055f303751110535fa46a6c 560 Gene3D G3DSA:3.20.20.140 483 559 4.8E-141 T 10-11-2016 A4G23_RS20180 ef55f0679055f303751110535fa46a6c 560 Gene3D G3DSA:3.20.20.140 141 424 4.8E-141 T 10-11-2016 A4G23_RS20480 73abf65f92846dccc6e7b0de40ef9da7 854 SUPERFAMILY SSF81593 177 278 1.49E-8 T 10-11-2016 A4G23_RS20480 73abf65f92846dccc6e7b0de40ef9da7 854 PIRSF PIRSF006288 3 854 1.3E-189 T 10-11-2016 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 A4G23_RS20480 73abf65f92846dccc6e7b0de40ef9da7 854 Hamap MF_00277 Bifunctional uridylyltransferase/uridylyl-removing enzyme [glnD]. 1 854 97.659 T 10-11-2016 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 A4G23_RS20480 73abf65f92846dccc6e7b0de40ef9da7 854 SUPERFAMILY SSF81301 38 158 2.03E-17 T 10-11-2016 A4G23_RS20480 73abf65f92846dccc6e7b0de40ef9da7 854 SMART SM00471 432 564 8.8E-8 T 10-11-2016 IPR003607 HD/PDEase domain A4G23_RS20480 73abf65f92846dccc6e7b0de40ef9da7 854 Gene3D G3DSA:3.30.460.10 62 122 1.0E-4 T 10-11-2016 A4G23_RS20480 73abf65f92846dccc6e7b0de40ef9da7 854 Pfam PF01966 HD domain 437 554 3.7E-13 T 10-11-2016 IPR006674 HD domain A4G23_RS20480 73abf65f92846dccc6e7b0de40ef9da7 854 TIGRFAM TIGR01693 UTase_glnD: protein-P-II uridylyltransferase 24 852 5.5E-233 T 10-11-2016 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 A4G23_RS20480 73abf65f92846dccc6e7b0de40ef9da7 854 Gene3D G3DSA:1.10.3210.10 417 578 7.1E-21 T 10-11-2016 IPR006674 HD domain A4G23_RS20480 73abf65f92846dccc6e7b0de40ef9da7 854 SUPERFAMILY SSF55021 782 833 3.24E-8 T 10-11-2016 A4G23_RS20480 73abf65f92846dccc6e7b0de40ef9da7 854 SUPERFAMILY SSF109604 403 553 2.12E-16 T 10-11-2016 A4G23_RS20480 73abf65f92846dccc6e7b0de40ef9da7 854 Pfam PF08335 GlnD PII-uridylyltransferase 209 280 4.7E-9 T 10-11-2016 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 A4G23_RS20480 73abf65f92846dccc6e7b0de40ef9da7 854 Pfam PF01842 ACT domain 783 830 2.6E-7 T 10-11-2016 IPR002912 ACT domain GO:0008152|GO:0016597 A4G23_RS20480 73abf65f92846dccc6e7b0de40ef9da7 854 Gene3D G3DSA:3.30.70.260 783 833 4.2E-8 T 10-11-2016 A4G23_RS16645 498f23f42d382da90de4344d014e7b9f 74 SUPERFAMILY SSF46561 5 67 1.44E-24 T 10-11-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS16645 498f23f42d382da90de4344d014e7b9f 74 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 5 64 18.374 T 10-11-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS16645 498f23f42d382da90de4344d014e7b9f 74 ProSitePatterns PS00579 Ribosomal protein L29 signature. 43 57 - T 10-11-2016 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS16645 498f23f42d382da90de4344d014e7b9f 74 TIGRFAM TIGR00012 L29: ribosomal protein uL29 9 64 1.1E-22 T 10-11-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS16645 498f23f42d382da90de4344d014e7b9f 74 Pfam PF00831 Ribosomal L29 protein 8 64 3.1E-27 T 10-11-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS16645 498f23f42d382da90de4344d014e7b9f 74 Gene3D G3DSA:1.10.287.310 6 69 6.5E-33 T 10-11-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS08520 709dd2b418d045f1fda629c590422b11 687 Pfam PF00498 FHA domain 599 677 3.0E-14 T 10-11-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 A4G23_RS08520 709dd2b418d045f1fda629c590422b11 687 Gene3D G3DSA:2.60.200.20 576 684 1.3E-20 T 10-11-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 A4G23_RS08520 709dd2b418d045f1fda629c590422b11 687 SUPERFAMILY SSF49879 579 682 4.02E-21 T 10-11-2016 IPR008984 SMAD/FHA domain GO:0005515 A4G23_RS08520 709dd2b418d045f1fda629c590422b11 687 SMART SM00240 598 658 8.9E-4 T 10-11-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 A4G23_RS10910 95c63411c546f8df21aa5a9f51902a51 106 Pfam PF09723 Zinc ribbon domain 2 40 4.9E-13 T 10-11-2016 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain A4G23_RS10910 95c63411c546f8df21aa5a9f51902a51 106 SMART SM00834 2 41 1.2E-13 T 10-11-2016 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain A4G23_RS10910 95c63411c546f8df21aa5a9f51902a51 106 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 2 51 1.4E-19 T 10-11-2016 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain A4G23_RS13520 c9f74b91a831d0c8ab60bc7897d5ec12 324 Gene3D G3DSA:3.50.50.60 270 306 3.6E-9 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS13520 c9f74b91a831d0c8ab60bc7897d5ec12 324 Gene3D G3DSA:3.50.50.60 105 129 3.6E-9 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS13520 c9f74b91a831d0c8ab60bc7897d5ec12 324 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 234 255 4.2E-80 T 10-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4G23_RS13520 c9f74b91a831d0c8ab60bc7897d5ec12 324 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 196 212 4.2E-80 T 10-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4G23_RS13520 c9f74b91a831d0c8ab60bc7897d5ec12 324 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 107 115 4.2E-80 T 10-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4G23_RS13520 c9f74b91a831d0c8ab60bc7897d5ec12 324 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 269 287 4.2E-80 T 10-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4G23_RS13520 c9f74b91a831d0c8ab60bc7897d5ec12 324 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 40 55 4.2E-80 T 10-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4G23_RS13520 c9f74b91a831d0c8ab60bc7897d5ec12 324 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 61 71 4.2E-80 T 10-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4G23_RS13520 c9f74b91a831d0c8ab60bc7897d5ec12 324 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 129 141 4.2E-80 T 10-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4G23_RS13520 c9f74b91a831d0c8ab60bc7897d5ec12 324 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 144 168 4.2E-80 T 10-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4G23_RS13520 c9f74b91a831d0c8ab60bc7897d5ec12 324 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 6 28 4.2E-80 T 10-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4G23_RS13520 c9f74b91a831d0c8ab60bc7897d5ec12 324 Gene3D G3DSA:3.50.50.60 130 240 1.2E-35 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS13520 c9f74b91a831d0c8ab60bc7897d5ec12 324 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 295 2.7E-49 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS13520 c9f74b91a831d0c8ab60bc7897d5ec12 324 Gene3D G3DSA:3.50.50.60 5 104 1.5E-32 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS13520 c9f74b91a831d0c8ab60bc7897d5ec12 324 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 136 156 - T 10-11-2016 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 A4G23_RS13520 c9f74b91a831d0c8ab60bc7897d5ec12 324 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 6 306 1.0E-121 T 10-11-2016 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00240+1.8.1.9|KEGG: 00450+1.8.1.9 A4G23_RS13520 c9f74b91a831d0c8ab60bc7897d5ec12 324 SUPERFAMILY SSF51905 5 305 7.45E-54 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS13520 c9f74b91a831d0c8ab60bc7897d5ec12 324 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 259 281 2.3E-38 T 10-11-2016 A4G23_RS13520 c9f74b91a831d0c8ab60bc7897d5ec12 324 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 232 248 2.3E-38 T 10-11-2016 A4G23_RS13520 c9f74b91a831d0c8ab60bc7897d5ec12 324 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 2.3E-38 T 10-11-2016 A4G23_RS13520 c9f74b91a831d0c8ab60bc7897d5ec12 324 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 2.3E-38 T 10-11-2016 A4G23_RS13520 c9f74b91a831d0c8ab60bc7897d5ec12 324 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 148 166 2.3E-38 T 10-11-2016 A4G23_RS02855 38fb2d3b117a41a9ba9395e6433670f0 356 Gene3D G3DSA:3.40.50.2300 31 151 5.1E-27 T 10-11-2016 A4G23_RS02855 38fb2d3b117a41a9ba9395e6433670f0 356 Pfam PF13407 Periplasmic binding protein domain 33 291 5.3E-57 T 10-11-2016 IPR025997 Periplasmic binding protein A4G23_RS02855 38fb2d3b117a41a9ba9395e6433670f0 356 SUPERFAMILY SSF53822 31 327 5.55E-57 T 10-11-2016 IPR028082 Periplasmic binding protein-like I A4G23_RS02855 38fb2d3b117a41a9ba9395e6433670f0 356 Gene3D G3DSA:3.40.50.2300 152 327 2.0E-34 T 10-11-2016 A4G23_RS20115 2d95acc51b519fe08b430ced1a40337d 980 SUPERFAMILY SSF55785 363 461 2.23E-16 T 10-11-2016 IPR000014 PAS domain A4G23_RS20115 2d95acc51b519fe08b430ced1a40337d 980 SMART SM00052 683 930 1.4E-52 T 10-11-2016 IPR001633 EAL domain A4G23_RS20115 2d95acc51b519fe08b430ced1a40337d 980 Gene3D G3DSA:3.20.20.450 687 937 1.7E-76 T 10-11-2016 IPR001633 EAL domain A4G23_RS20115 2d95acc51b519fe08b430ced1a40337d 980 Pfam PF00990 Diguanylate cyclase, GGDEF domain 507 669 2.3E-42 T 10-11-2016 IPR000160 GGDEF domain A4G23_RS20115 2d95acc51b519fe08b430ced1a40337d 980 SUPERFAMILY SSF55073 512 674 6.98E-45 T 10-11-2016 IPR029787 Nucleotide cyclase A4G23_RS20115 2d95acc51b519fe08b430ced1a40337d 980 Pfam PF08448 PAS fold 379 498 3.3E-7 T 10-11-2016 IPR013656 PAS fold-4 A4G23_RS20115 2d95acc51b519fe08b430ced1a40337d 980 SUPERFAMILY SSF141868 690 935 1.7E-57 T 10-11-2016 IPR001633 EAL domain A4G23_RS20115 2d95acc51b519fe08b430ced1a40337d 980 Gene3D G3DSA:3.30.70.270 508 681 2.7E-56 T 10-11-2016 A4G23_RS20115 2d95acc51b519fe08b430ced1a40337d 980 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 503 672 8.3E-41 T 10-11-2016 IPR000160 GGDEF domain A4G23_RS20115 2d95acc51b519fe08b430ced1a40337d 980 SMART SM00091 372 438 2.1E-10 T 10-11-2016 IPR000014 PAS domain A4G23_RS20115 2d95acc51b519fe08b430ced1a40337d 980 Gene3D G3DSA:3.30.450.20 364 494 2.0E-17 T 10-11-2016 A4G23_RS20115 2d95acc51b519fe08b430ced1a40337d 980 SMART SM00267 496 673 1.9E-59 T 10-11-2016 IPR000160 GGDEF domain A4G23_RS20115 2d95acc51b519fe08b430ced1a40337d 980 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 369 503 2.2E-12 T 10-11-2016 IPR000014 PAS domain A4G23_RS20115 2d95acc51b519fe08b430ced1a40337d 980 Pfam PF00563 EAL domain 690 925 2.9E-55 T 10-11-2016 IPR001633 EAL domain A4G23_RS03910 37d196912fbbef0d2f7b62325e061336 1318 Gene3D G3DSA:1.10.1610.10 970 1041 2.1E-28 T 10-11-2016 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 A4G23_RS03910 37d196912fbbef0d2f7b62325e061336 1318 SUPERFAMILY SSF52733 972 1316 3.66E-112 T 10-11-2016 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 A4G23_RS03910 37d196912fbbef0d2f7b62325e061336 1318 Pfam PF02277 Phosphoribosyltransferase 978 1315 2.3E-125 T 10-11-2016 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 A4G23_RS03910 37d196912fbbef0d2f7b62325e061336 1318 Gene3D G3DSA:3.40.109.10 751 959 1.5E-51 T 10-11-2016 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4G23_RS03910 37d196912fbbef0d2f7b62325e061336 1318 SUPERFAMILY SSF55469 756 960 8.11E-53 T 10-11-2016 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4G23_RS03910 37d196912fbbef0d2f7b62325e061336 1318 PRINTS PR01217 Proline rich extensin signature 64 76 5.5E-9 T 10-11-2016 A4G23_RS03910 37d196912fbbef0d2f7b62325e061336 1318 PRINTS PR01217 Proline rich extensin signature 141 158 5.5E-9 T 10-11-2016 A4G23_RS03910 37d196912fbbef0d2f7b62325e061336 1318 PRINTS PR01217 Proline rich extensin signature 22 38 5.5E-9 T 10-11-2016 A4G23_RS03910 37d196912fbbef0d2f7b62325e061336 1318 PRINTS PR01217 Proline rich extensin signature 115 131 5.5E-9 T 10-11-2016 A4G23_RS03910 37d196912fbbef0d2f7b62325e061336 1318 PRINTS PR01217 Proline rich extensin signature 220 245 5.5E-9 T 10-11-2016 A4G23_RS03910 37d196912fbbef0d2f7b62325e061336 1318 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 980 1317 34.748 T 10-11-2016 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 A4G23_RS03910 37d196912fbbef0d2f7b62325e061336 1318 Gene3D G3DSA:3.40.50.10210 1042 1298 1.6E-110 T 10-11-2016 A4G23_RS03910 37d196912fbbef0d2f7b62325e061336 1318 TIGRFAM TIGR02476 BluB: 5,6-dimethylbenzimidazole synthase 748 953 1.3E-91 T 10-11-2016 IPR012825 5,6-dimethylbenzimidazole synthase BluB KEGG: 00740+1.13.11.79|MetaCyc: PWY-5508|MetaCyc: PWY-5523 A4G23_RS03910 37d196912fbbef0d2f7b62325e061336 1318 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 982 1315 1.9E-124 T 10-11-2016 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 A4G23_RS03910 37d196912fbbef0d2f7b62325e061336 1318 Pfam PF00881 Nitroreductase family 760 927 4.0E-32 T 10-11-2016 IPR029479 Nitroreductase Reactome: R-HSA-209968 A4G23_RS03165 d6c525be8b3353848aba143fb6d5881a 921 SMART SM00387 503 613 1.4E-4 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS03165 d6c525be8b3353848aba143fb6d5881a 921 Pfam PF00672 HAMP domain 303 387 7.4E-10 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS03165 d6c525be8b3353848aba143fb6d5881a 921 SUPERFAMILY SSF55874 489 611 1.96E-17 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS03165 d6c525be8b3353848aba143fb6d5881a 921 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 507 611 4.1E-6 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS03165 d6c525be8b3353848aba143fb6d5881a 921 Gene3D G3DSA:3.30.565.10 470 618 9.2E-14 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS03165 d6c525be8b3353848aba143fb6d5881a 921 Pfam PF08376 Nitrate and nitrite sensing 44 282 1.2E-34 T 10-11-2016 IPR013587 Nitrate/nitrite sensing protein A4G23_RS16125 fa7fc8ac3ff3d8abf6af16ec4d6c8589 275 Gene3D G3DSA:2.60.130.10 60 214 4.7E-45 T 10-11-2016 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 A4G23_RS16125 fa7fc8ac3ff3d8abf6af16ec4d6c8589 275 Pfam PF00775 Dioxygenase 68 211 2.6E-18 T 10-11-2016 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 A4G23_RS16125 fa7fc8ac3ff3d8abf6af16ec4d6c8589 275 Pfam PF02839 Carbohydrate binding domain 231 272 3.7E-6 T 10-11-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 A4G23_RS16125 fa7fc8ac3ff3d8abf6af16ec4d6c8589 275 SUPERFAMILY SSF49482 60 213 4.06E-46 T 10-11-2016 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 A4G23_RS16125 fa7fc8ac3ff3d8abf6af16ec4d6c8589 275 Gene3D G3DSA:2.10.10.20 231 273 1.3E-22 T 10-11-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 A4G23_RS16125 fa7fc8ac3ff3d8abf6af16ec4d6c8589 275 SMART SM00495 229 275 4.2E-9 T 10-11-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 A4G23_RS16125 fa7fc8ac3ff3d8abf6af16ec4d6c8589 275 SUPERFAMILY SSF51055 232 273 1.2E-15 T 10-11-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 A4G23_RS19970 c9837a253af4fbb6d2d00d1752a923f0 257 Pfam PF07179 SseB protein N-terminal domain 4 115 4.5E-14 T 10-11-2016 IPR009839 SseB protein N-terminal domain A4G23_RS19970 c9837a253af4fbb6d2d00d1752a923f0 257 Pfam PF14581 SseB protein C-terminal domain 143 253 8.3E-25 T 10-11-2016 IPR027945 SseB protein, C-terminal A4G23_RS22535 8dac1c89fb5adfc7f818f65a3f3072f5 166 Pfam PF13508 Acetyltransferase (GNAT) domain 66 141 5.3E-13 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS22535 8dac1c89fb5adfc7f818f65a3f3072f5 166 SUPERFAMILY SSF55729 16 161 1.4E-25 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS22535 8dac1c89fb5adfc7f818f65a3f3072f5 166 Gene3D G3DSA:3.40.630.30 17 164 2.7E-27 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS01225 252b49e043df9756abbb09bc4f5e674e 230 Pfam PF13560 Helix-turn-helix domain 10 67 2.0E-10 T 10-11-2016 A4G23_RS01225 252b49e043df9756abbb09bc4f5e674e 230 Gene3D G3DSA:1.10.260.40 11 81 4.4E-14 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS01225 252b49e043df9756abbb09bc4f5e674e 230 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 93 213 1.1E-22 T 10-11-2016 IPR024747 Pyridoxamine 5'-phosphate oxidase-related A4G23_RS01225 252b49e043df9756abbb09bc4f5e674e 230 Gene3D G3DSA:2.30.110.10 86 219 8.9E-40 T 10-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 A4G23_RS01225 252b49e043df9756abbb09bc4f5e674e 230 SMART SM00530 14 69 1.2E-10 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS01225 252b49e043df9756abbb09bc4f5e674e 230 SUPERFAMILY SSF50475 89 214 1.69E-20 T 10-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 A4G23_RS01225 252b49e043df9756abbb09bc4f5e674e 230 SUPERFAMILY SSF47413 9 75 3.66E-12 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS16335 6839bd80ca6f7f3f79d6bb2a8b46a30a 95 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 42 91 3.3E-20 T 10-11-2016 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A4G23_RS16335 6839bd80ca6f7f3f79d6bb2a8b46a30a 95 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 41 95 8.1E-22 T 10-11-2016 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 A4G23_RS16335 6839bd80ca6f7f3f79d6bb2a8b46a30a 95 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 42 70 - T 10-11-2016 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A4G23_RS16335 6839bd80ca6f7f3f79d6bb2a8b46a30a 95 Gene3D G3DSA:1.20.5.1030 37 94 1.1E-22 T 10-11-2016 A4G23_RS16335 6839bd80ca6f7f3f79d6bb2a8b46a30a 95 Hamap MF_00422 Protein translocase subunit SecE [secE]. 37 92 13.104 T 10-11-2016 IPR022943 Preprotein translocase subunit SecE Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A4G23_RS00930 d6b59fefdf70342acfd47bd33076d79c 677 SUPERFAMILY SSF51905 467 525 1.09E-21 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS00930 d6b59fefdf70342acfd47bd33076d79c 677 SUPERFAMILY SSF51905 561 655 1.09E-21 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS00930 d6b59fefdf70342acfd47bd33076d79c 677 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 13 337 1.7E-82 T 10-11-2016 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 A4G23_RS00930 d6b59fefdf70342acfd47bd33076d79c 677 Gene3D G3DSA:3.20.20.70 10 366 2.2E-122 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS00930 d6b59fefdf70342acfd47bd33076d79c 677 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 384 403 3.2E-12 T 10-11-2016 A4G23_RS00930 d6b59fefdf70342acfd47bd33076d79c 677 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 504 522 3.2E-12 T 10-11-2016 A4G23_RS00930 d6b59fefdf70342acfd47bd33076d79c 677 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 623 639 3.2E-12 T 10-11-2016 A4G23_RS00930 d6b59fefdf70342acfd47bd33076d79c 677 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 624 638 2.3E-6 T 10-11-2016 A4G23_RS00930 d6b59fefdf70342acfd47bd33076d79c 677 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 383 405 2.3E-6 T 10-11-2016 A4G23_RS00930 d6b59fefdf70342acfd47bd33076d79c 677 SUPERFAMILY SSF51395 7 369 4.51E-113 T 10-11-2016 A4G23_RS00930 d6b59fefdf70342acfd47bd33076d79c 677 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 382 653 8.9E-28 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS00930 d6b59fefdf70342acfd47bd33076d79c 677 SUPERFAMILY SSF51971 340 525 8.36E-41 T 10-11-2016 A4G23_RS00930 d6b59fefdf70342acfd47bd33076d79c 677 Gene3D G3DSA:3.50.50.60 476 630 4.6E-49 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS00930 d6b59fefdf70342acfd47bd33076d79c 677 Gene3D G3DSA:3.50.50.60 367 471 1.1E-27 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS25500 88529696c91fce9664c712cef00802f9 561 SUPERFAMILY SSF142984 392 474 1.96E-15 T 10-11-2016 A4G23_RS25500 88529696c91fce9664c712cef00802f9 561 SUPERFAMILY SSF140490 479 555 5.75E-13 T 10-11-2016 A4G23_RS25500 88529696c91fce9664c712cef00802f9 561 SMART SM00928 480 525 1.8E-4 T 10-11-2016 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS25500 88529696c91fce9664c712cef00802f9 561 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 25 133 8.0E-12 T 10-11-2016 A4G23_RS25500 88529696c91fce9664c712cef00802f9 561 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 482 554 1.2E-11 T 10-11-2016 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS25500 88529696c91fce9664c712cef00802f9 561 SUPERFAMILY SSF142019 184 391 7.72E-64 T 10-11-2016 A4G23_RS25500 88529696c91fce9664c712cef00802f9 561 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 202 370 2.6E-42 T 10-11-2016 IPR011538 NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS25500 88529696c91fce9664c712cef00802f9 561 SUPERFAMILY SSF52833 14 138 2.91E-15 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS25500 88529696c91fce9664c712cef00802f9 561 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 493 504 - T 10-11-2016 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS07895 e314ffff8a4bab189a3d1a4c245a846f 376 SUPERFAMILY SSF53613 36 329 4.68E-49 T 10-11-2016 IPR029056 Ribokinase-like A4G23_RS07895 e314ffff8a4bab189a3d1a4c245a846f 376 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 274 287 - T 10-11-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A4G23_RS07895 e314ffff8a4bab189a3d1a4c245a846f 376 Gene3D G3DSA:3.40.1190.20 36 331 3.8E-55 T 10-11-2016 IPR029056 Ribokinase-like A4G23_RS07895 e314ffff8a4bab189a3d1a4c245a846f 376 Pfam PF00294 pfkB family carbohydrate kinase 63 321 3.9E-34 T 10-11-2016 IPR011611 Carbohydrate kinase PfkB A4G23_RS21935 d5d641390ae9c2718f0126b4ddbf24a6 327 Gene3D G3DSA:3.30.1490.20 121 180 1.2E-5 T 10-11-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A4G23_RS21935 d5d641390ae9c2718f0126b4ddbf24a6 327 SUPERFAMILY SSF56059 116 316 3.54E-20 T 10-11-2016 A4G23_RS21935 d5d641390ae9c2718f0126b4ddbf24a6 327 Gene3D G3DSA:3.40.50.20 59 120 3.8E-4 T 10-11-2016 IPR016185 Pre-ATP-grasp domain A4G23_RS21935 d5d641390ae9c2718f0126b4ddbf24a6 327 Gene3D G3DSA:3.30.470.20 260 324 3.2E-4 T 10-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 A4G23_RS22875 b5a44fcff294a12e87fcb1b4511e962b 365 SUPERFAMILY SSF53822 39 338 5.55E-63 T 10-11-2016 IPR028082 Periplasmic binding protein-like I A4G23_RS22875 b5a44fcff294a12e87fcb1b4511e962b 365 Pfam PF13407 Periplasmic binding protein domain 42 301 3.3E-58 T 10-11-2016 IPR025997 Periplasmic binding protein A4G23_RS22875 b5a44fcff294a12e87fcb1b4511e962b 365 Gene3D G3DSA:3.40.50.2300 154 338 1.4E-39 T 10-11-2016 A4G23_RS22875 b5a44fcff294a12e87fcb1b4511e962b 365 Gene3D G3DSA:3.40.50.2300 40 153 1.1E-23 T 10-11-2016 A4G23_RS15110 428d775567fd35e594ad538ea6aea8eb 480 SUPERFAMILY SSF56059 127 338 4.6E-26 T 10-11-2016 A4G23_RS15110 428d775567fd35e594ad538ea6aea8eb 480 Gene3D G3DSA:3.30.1490.20 120 169 6.6E-6 T 10-11-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A4G23_RS15110 428d775567fd35e594ad538ea6aea8eb 480 Gene3D G3DSA:3.30.470.20 226 331 3.2E-11 T 10-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 A4G23_RS15460 38b32aaa1277df934af4088ef8ee03a0 173 Pfam PF08281 Sigma-70, region 4 104 155 1.9E-16 T 10-11-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS15460 38b32aaa1277df934af4088ef8ee03a0 173 SUPERFAMILY SSF88946 3 75 6.28E-12 T 10-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS15460 38b32aaa1277df934af4088ef8ee03a0 173 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 7 162 2.1E-60 T 10-11-2016 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 A4G23_RS15460 38b32aaa1277df934af4088ef8ee03a0 173 Gene3D G3DSA:1.10.1740.10 7 79 2.6E-13 T 10-11-2016 A4G23_RS15460 38b32aaa1277df934af4088ef8ee03a0 173 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 34 65 - T 10-11-2016 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS15460 38b32aaa1277df934af4088ef8ee03a0 173 Gene3D G3DSA:1.10.10.10 97 160 9.5E-22 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS15460 38b32aaa1277df934af4088ef8ee03a0 173 Pfam PF04542 Sigma-70 region 2 16 78 2.4E-7 T 10-11-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS15460 38b32aaa1277df934af4088ef8ee03a0 173 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 10 159 5.3E-26 T 10-11-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS15460 38b32aaa1277df934af4088ef8ee03a0 173 SUPERFAMILY SSF88659 89 162 5.98E-17 T 10-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS23745 ffa40625773bc96a1e21b116226e7599 1254 SUPERFAMILY SSF53706 9 350 0.0 T 10-11-2016 A4G23_RS23745 ffa40625773bc96a1e21b116226e7599 1254 SUPERFAMILY SSF53706 381 1086 0.0 T 10-11-2016 A4G23_RS23745 ffa40625773bc96a1e21b116226e7599 1254 TIGRFAM TIGR01580 narG: nitrate reductase, alpha subunit 14 1247 0.0 T 10-11-2016 IPR006468 Nitrate reductase, alpha subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.99.4 A4G23_RS23745 ffa40625773bc96a1e21b116226e7599 1254 Gene3D G3DSA:3.90.55.10 799 852 2.4E-4 T 10-11-2016 A4G23_RS23745 ffa40625773bc96a1e21b116226e7599 1254 Pfam PF01568 Molydopterin dinucleotide binding domain 1107 1216 7.4E-21 T 10-11-2016 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 A4G23_RS23745 ffa40625773bc96a1e21b116226e7599 1254 Pfam PF00384 Molybdopterin oxidoreductase 112 849 1.3E-140 T 10-11-2016 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS23745 ffa40625773bc96a1e21b116226e7599 1254 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 52 70 - T 10-11-2016 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 A4G23_RS23745 ffa40625773bc96a1e21b116226e7599 1254 SMART SM00926 47 109 9.0E-6 T 10-11-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS23745 ffa40625773bc96a1e21b116226e7599 1254 SUPERFAMILY SSF50692 1107 1247 4.07E-42 T 10-11-2016 IPR009010 Aspartate decarboxylase-like domain A4G23_RS23745 ffa40625773bc96a1e21b116226e7599 1254 Gene3D G3DSA:2.40.40.20 1076 1248 1.4E-37 T 10-11-2016 A4G23_RS23745 ffa40625773bc96a1e21b116226e7599 1254 Gene3D G3DSA:2.20.25.90 56 101 1.8E-29 T 10-11-2016 A4G23_RS23745 ffa40625773bc96a1e21b116226e7599 1254 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 795 812 - T 10-11-2016 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 A4G23_RS23745 ffa40625773bc96a1e21b116226e7599 1254 Gene3D G3DSA:3.40.50.740 153 195 1.0E-6 T 10-11-2016 A4G23_RS23745 ffa40625773bc96a1e21b116226e7599 1254 Gene3D G3DSA:3.40.50.740 614 798 1.3E-51 T 10-11-2016 A4G23_RS23745 ffa40625773bc96a1e21b116226e7599 1254 Gene3D G3DSA:3.40.228.10 225 340 3.7E-85 T 10-11-2016 A4G23_RS23745 ffa40625773bc96a1e21b116226e7599 1254 Gene3D G3DSA:3.40.228.10 512 613 3.7E-85 T 10-11-2016 A4G23_RS21195 10bc4a508c0b269a983879794af1ee54 224 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 31 220 5.1E-12 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS21195 10bc4a508c0b269a983879794af1ee54 224 Gene3D G3DSA:1.10.3720.10 11 220 4.2E-35 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS21195 10bc4a508c0b269a983879794af1ee54 224 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 114 2.8E-13 T 10-11-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 A4G23_RS21195 10bc4a508c0b269a983879794af1ee54 224 SUPERFAMILY SSF161098 12 205 9.38E-34 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS13725 dc4a2ba3b34e0b7982754f0fc0b7af72 368 Pfam PF01551 Peptidase family M23 256 343 1.6E-25 T 10-11-2016 IPR016047 Peptidase M23 A4G23_RS13725 dc4a2ba3b34e0b7982754f0fc0b7af72 368 Gene3D G3DSA:2.70.70.10 219 358 6.7E-39 T 10-11-2016 A4G23_RS13725 dc4a2ba3b34e0b7982754f0fc0b7af72 368 SUPERFAMILY SSF51261 236 357 2.04E-40 T 10-11-2016 IPR011055 Duplicated hybrid motif A4G23_RS08115 392d2dff6b58f05033d5e43c3da25237 503 PIRSF PIRSF036586 10 484 3.2E-169 T 10-11-2016 IPR012115 Bifunctional ribulose 5-phosphate reductase/CDP-ribitol pyrophosphorylase A4G23_RS08115 392d2dff6b58f05033d5e43c3da25237 503 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 386 414 - T 10-11-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4G23_RS08115 392d2dff6b58f05033d5e43c3da25237 503 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 16 246 4.3E-45 T 10-11-2016 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 A4G23_RS08115 392d2dff6b58f05033d5e43c3da25237 503 Gene3D G3DSA:3.90.550.10 12 249 9.3E-59 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS08115 392d2dff6b58f05033d5e43c3da25237 503 Gene3D G3DSA:3.40.50.720 268 477 3.5E-42 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS08115 392d2dff6b58f05033d5e43c3da25237 503 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 14 251 26.922 T 10-11-2016 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 A4G23_RS08115 392d2dff6b58f05033d5e43c3da25237 503 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 327 338 2.4E-17 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS08115 392d2dff6b58f05033d5e43c3da25237 503 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 399 418 2.4E-17 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS08115 392d2dff6b58f05033d5e43c3da25237 503 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 272 289 2.4E-17 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS08115 392d2dff6b58f05033d5e43c3da25237 503 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 420 437 2.4E-17 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS08115 392d2dff6b58f05033d5e43c3da25237 503 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 399 418 7.0E-6 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS08115 392d2dff6b58f05033d5e43c3da25237 503 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 327 338 7.0E-6 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS08115 392d2dff6b58f05033d5e43c3da25237 503 SUPERFAMILY SSF53448 15 249 1.4E-46 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS08115 392d2dff6b58f05033d5e43c3da25237 503 SUPERFAMILY SSF51735 268 475 1.55E-43 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS08115 392d2dff6b58f05033d5e43c3da25237 503 Pfam PF00106 short chain dehydrogenase 272 441 5.6E-27 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS20800 ab23eda3d639ba096f7ecb4641b7d06e 197 Gene3D G3DSA:1.20.144.10 10 172 4.1E-20 T 10-11-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A4G23_RS20800 ab23eda3d639ba096f7ecb4641b7d06e 197 SUPERFAMILY SSF48317 4 170 1.31E-21 T 10-11-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A4G23_RS20800 ab23eda3d639ba096f7ecb4641b7d06e 197 Pfam PF01569 PAP2 superfamily 96 172 5.6E-7 T 10-11-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A4G23_RS21030 0997126a918286d28e08710c4b7c4b92 299 PRINTS PR00146 Dihydrodipicolinate synthase signature 80 98 2.3E-31 T 10-11-2016 IPR002220 DapA-like GO:0008152|GO:0016829 A4G23_RS21030 0997126a918286d28e08710c4b7c4b92 299 PRINTS PR00146 Dihydrodipicolinate synthase signature 137 154 2.3E-31 T 10-11-2016 IPR002220 DapA-like GO:0008152|GO:0016829 A4G23_RS21030 0997126a918286d28e08710c4b7c4b92 299 PRINTS PR00146 Dihydrodipicolinate synthase signature 112 128 2.3E-31 T 10-11-2016 IPR002220 DapA-like GO:0008152|GO:0016829 A4G23_RS21030 0997126a918286d28e08710c4b7c4b92 299 PRINTS PR00146 Dihydrodipicolinate synthase signature 44 65 2.3E-31 T 10-11-2016 IPR002220 DapA-like GO:0008152|GO:0016829 A4G23_RS21030 0997126a918286d28e08710c4b7c4b92 299 Gene3D G3DSA:3.20.20.70 9 294 2.5E-108 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS21030 0997126a918286d28e08710c4b7c4b92 299 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 14 290 4.1E-87 T 10-11-2016 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4G23_RS21030 0997126a918286d28e08710c4b7c4b92 299 SUPERFAMILY SSF51569 7 294 5.55E-97 T 10-11-2016 A4G23_RS21030 0997126a918286d28e08710c4b7c4b92 299 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 142 172 - T 10-11-2016 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4G23_RS21030 0997126a918286d28e08710c4b7c4b92 299 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 47 64 - T 10-11-2016 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4G23_RS21030 0997126a918286d28e08710c4b7c4b92 299 PIRSF PIRSF001365 7 298 9.6E-82 T 10-11-2016 IPR002220 DapA-like GO:0008152|GO:0016829 A4G23_RS21030 0997126a918286d28e08710c4b7c4b92 299 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 10 294 58.203 T 10-11-2016 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4G23_RS21030 0997126a918286d28e08710c4b7c4b92 299 Pfam PF00701 Dihydrodipicolinate synthetase family 11 293 3.0E-83 T 10-11-2016 IPR002220 DapA-like GO:0008152|GO:0016829 A4G23_RS21030 0997126a918286d28e08710c4b7c4b92 299 SMART SM01130 10 295 1.6E-122 T 10-11-2016 IPR002220 DapA-like GO:0008152|GO:0016829 A4G23_RS19810 2142ec8a0b8e792878a84498e970df1f 645 Pfam PF13188 PAS domain 212 264 1.4E-5 T 10-11-2016 IPR000014 PAS domain A4G23_RS19810 2142ec8a0b8e792878a84498e970df1f 645 Gene3D G3DSA:3.30.565.10 381 527 3.0E-28 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS19810 2142ec8a0b8e792878a84498e970df1f 645 PRINTS PR00344 Bacterial sensor protein C-terminal signature 509 522 1.8E-9 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS19810 2142ec8a0b8e792878a84498e970df1f 645 PRINTS PR00344 Bacterial sensor protein C-terminal signature 456 470 1.8E-9 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS19810 2142ec8a0b8e792878a84498e970df1f 645 PRINTS PR00344 Bacterial sensor protein C-terminal signature 485 503 1.8E-9 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS19810 2142ec8a0b8e792878a84498e970df1f 645 SUPERFAMILY SSF55874 411 523 2.49E-26 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS19810 2142ec8a0b8e792878a84498e970df1f 645 SUPERFAMILY SSF55890 326 387 4.45E-5 T 10-11-2016 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 A4G23_RS19810 2142ec8a0b8e792878a84498e970df1f 645 Gene3D G3DSA:1.10.287.130 307 367 1.4E-11 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS19810 2142ec8a0b8e792878a84498e970df1f 645 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 420 524 9.0E-17 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS19810 2142ec8a0b8e792878a84498e970df1f 645 SUPERFAMILY SSF103190 40 168 1.14E-29 T 10-11-2016 IPR029151 Periplasmic sensor domain-like A4G23_RS19810 2142ec8a0b8e792878a84498e970df1f 645 SUPERFAMILY SSF55785 206 308 9.42E-7 T 10-11-2016 IPR000014 PAS domain A4G23_RS19810 2142ec8a0b8e792878a84498e970df1f 645 Gene3D G3DSA:3.30.450.20 208 306 7.1E-10 T 10-11-2016 A4G23_RS19810 2142ec8a0b8e792878a84498e970df1f 645 Pfam PF17203 Single cache domain 3 37 169 2.8E-29 T 10-11-2016 IPR033463 Single cache domain 3 A4G23_RS19810 2142ec8a0b8e792878a84498e970df1f 645 Gene3D G3DSA:3.30.450.20 35 170 6.2E-38 T 10-11-2016 A4G23_RS19810 2142ec8a0b8e792878a84498e970df1f 645 SMART SM00387 417 525 2.5E-25 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS06940 6e3d24da64a7ebe9b1de12732cfc2240 582 SUPERFAMILY SSF56317 3 254 2.62E-56 T 10-11-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 A4G23_RS06940 6e3d24da64a7ebe9b1de12732cfc2240 582 Gene3D G3DSA:3.60.110.10 3 253 1.9E-55 T 10-11-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 A4G23_RS06940 6e3d24da64a7ebe9b1de12732cfc2240 582 ProSitePatterns PS00920 Nitrilases / cyanide hydratase signature 1. 29 44 - T 10-11-2016 IPR000132 Nitrilase/cyanide hydratase, conserved site GO:0016810 A4G23_RS06940 6e3d24da64a7ebe9b1de12732cfc2240 582 Pfam PF00795 Carbon-nitrogen hydrolase 3 254 1.3E-23 T 10-11-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 A4G23_RS06940 6e3d24da64a7ebe9b1de12732cfc2240 582 Pfam PF02540 NAD synthase 302 549 2.3E-67 T 10-11-2016 IPR022310 NAD/GMP synthase A4G23_RS06940 6e3d24da64a7ebe9b1de12732cfc2240 582 SUPERFAMILY SSF52402 295 557 2.19E-73 T 10-11-2016 A4G23_RS06940 6e3d24da64a7ebe9b1de12732cfc2240 582 TIGRFAM TIGR00552 nadE: NAD+ synthetase 309 552 1.4E-54 T 10-11-2016 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 A4G23_RS06940 6e3d24da64a7ebe9b1de12732cfc2240 582 Gene3D G3DSA:3.40.50.620 295 557 4.4E-72 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS06940 6e3d24da64a7ebe9b1de12732cfc2240 582 PIRSF PIRSF006630 1 577 1.9E-209 T 10-11-2016 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: R-HSA-196807 A4G23_RS18200 21197ddd45951103de4b18018ce5ae4b 184 SUPERFAMILY SSF52833 2 177 3.09E-54 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS18200 21197ddd45951103de4b18018ce5ae4b 184 Pfam PF00578 AhpC/TSA family 4 136 8.6E-34 T 10-11-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A4G23_RS18200 21197ddd45951103de4b18018ce5ae4b 184 PIRSF PIRSF000239 1 184 3.2E-50 T 10-11-2016 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A4G23_RS18200 21197ddd45951103de4b18018ce5ae4b 184 Gene3D G3DSA:3.40.30.10 2 177 7.5E-62 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS16105 cc88837f80adf98374510aeefb350e3f 523 Pfam PF00361 Proton-conducting membrane transporter 139 443 2.3E-65 T 10-11-2016 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16105 cc88837f80adf98374510aeefb350e3f 523 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 6 509 3.9E-175 T 10-11-2016 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16105 cc88837f80adf98374510aeefb350e3f 523 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 261 285 7.3E-29 T 10-11-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16105 cc88837f80adf98374510aeefb350e3f 523 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 349 368 7.3E-29 T 10-11-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16105 cc88837f80adf98374510aeefb350e3f 523 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 186 210 7.3E-29 T 10-11-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16105 cc88837f80adf98374510aeefb350e3f 523 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 145 164 7.3E-29 T 10-11-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16105 cc88837f80adf98374510aeefb350e3f 523 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 401 427 7.3E-29 T 10-11-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS20075 b9beedd4847a071941f401e950b6cafb 499 Pfam PF01425 Amidase 27 473 5.0E-157 T 10-11-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4G23_RS20075 b9beedd4847a071941f401e950b6cafb 499 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 14 485 90.138 T 10-11-2016 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4G23_RS20075 b9beedd4847a071941f401e950b6cafb 499 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 16 484 4.4E-186 T 10-11-2016 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4G23_RS20075 b9beedd4847a071941f401e950b6cafb 499 Gene3D G3DSA:3.90.1300.10 3 486 6.0E-176 T 10-11-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4G23_RS20075 b9beedd4847a071941f401e950b6cafb 499 SUPERFAMILY SSF75304 3 483 2.22E-161 T 10-11-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4G23_RS20075 b9beedd4847a071941f401e950b6cafb 499 ProSitePatterns PS00571 Amidases signature. 155 186 - T 10-11-2016 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 A4G23_RS14025 9538a34cee0a42bc0729369fcd893396 436 SUPERFAMILY SSF56014 357 423 9.95E-7 T 10-11-2016 A4G23_RS14025 9538a34cee0a42bc0729369fcd893396 436 SUPERFAMILY SSF56014 118 223 1.6E-5 T 10-11-2016 A4G23_RS14025 9538a34cee0a42bc0729369fcd893396 436 Gene3D G3DSA:3.30.413.10 358 422 1.3E-4 T 10-11-2016 A4G23_RS14025 9538a34cee0a42bc0729369fcd893396 436 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 49 95 4.7E-10 T 10-11-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4G23_RS14025 9538a34cee0a42bc0729369fcd893396 436 SUPERFAMILY SSF55124 30 112 4.25E-17 T 10-11-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4G23_RS14025 9538a34cee0a42bc0729369fcd893396 436 SUPERFAMILY SSF55124 202 350 1.01E-10 T 10-11-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4G23_RS14025 9538a34cee0a42bc0729369fcd893396 436 Gene3D G3DSA:3.90.480.10 44 113 2.6E-15 T 10-11-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4G23_RS14025 9538a34cee0a42bc0729369fcd893396 436 Gene3D G3DSA:3.90.480.10 275 347 2.6E-15 T 10-11-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4G23_RS02605 0c8dd36131dfc96ed29d2ae525f263fe 83 SUPERFAMILY SSF47598 4 46 2.56E-6 T 10-11-2016 IPR010985 Ribbon-helix-helix GO:0006355 A4G23_RS25010 00eb08aeac577b4a8d2f99f88644f1c3 120 Pfam PF01899 Na+/H+ ion antiporter subunit 7 108 6.6E-19 T 10-11-2016 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 A4G23_RS04230 43756348641d4e7596a187111eae4128 942 SUPERFAMILY SSF52540 46 187 1.59E-43 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS04230 43756348641d4e7596a187111eae4128 942 SUPERFAMILY SSF52540 366 460 1.59E-43 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS04230 43756348641d4e7596a187111eae4128 942 SUPERFAMILY SSF52540 272 324 1.59E-43 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS04230 43756348641d4e7596a187111eae4128 942 Pfam PF13234 rRNA-processing arch domain 502 602 9.9E-5 T 10-11-2016 IPR025696 rRNA-processing arch domain A4G23_RS04230 43756348641d4e7596a187111eae4128 942 Gene3D G3DSA:3.40.50.300 33 216 1.0E-37 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS04230 43756348641d4e7596a187111eae4128 942 SMART SM01142 763 941 1.5E-60 T 10-11-2016 IPR012961 ATP-dependent RNA helicase Ski2, C-terminal A4G23_RS04230 43756348641d4e7596a187111eae4128 942 SMART SM00487 32 214 2.5E-32 T 10-11-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4G23_RS04230 43756348641d4e7596a187111eae4128 942 Pfam PF00271 Helicase conserved C-terminal domain 364 446 8.8E-5 T 10-11-2016 IPR001650 Helicase, C-terminal A4G23_RS04230 43756348641d4e7596a187111eae4128 942 Pfam PF00270 DEAD/DEAH box helicase 38 186 7.7E-20 T 10-11-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A4G23_RS04230 43756348641d4e7596a187111eae4128 942 SMART SM00490 357 446 2.9E-13 T 10-11-2016 IPR001650 Helicase, C-terminal A4G23_RS04230 43756348641d4e7596a187111eae4128 942 Gene3D G3DSA:3.40.50.300 369 456 2.1E-17 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS04230 43756348641d4e7596a187111eae4128 942 Gene3D G3DSA:3.40.50.300 295 327 2.1E-17 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS04230 43756348641d4e7596a187111eae4128 942 Pfam PF08148 DSHCT (NUC185) domain 766 936 2.9E-36 T 10-11-2016 IPR012961 ATP-dependent RNA helicase Ski2, C-terminal A4G23_RS16775 320c8e6a260f0f0209927ad395eed49c 452 SUPERFAMILY SSF55957 364 452 3.53E-22 T 10-11-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS16775 320c8e6a260f0f0209927ad395eed49c 452 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 379 447 7.0E-14 T 10-11-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS16775 320c8e6a260f0f0209927ad395eed49c 452 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 448 4.9E-169 T 10-11-2016 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS16775 320c8e6a260f0f0209927ad395eed49c 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 239 254 1.2E-11 T 10-11-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS16775 320c8e6a260f0f0209927ad395eed49c 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 179 198 1.2E-11 T 10-11-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS16775 320c8e6a260f0f0209927ad395eed49c 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 97 111 1.2E-11 T 10-11-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS16775 320c8e6a260f0f0209927ad395eed49c 452 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 450 43.96 T 10-11-2016 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS16775 320c8e6a260f0f0209927ad395eed49c 452 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 138 1.4E-37 T 10-11-2016 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS16775 320c8e6a260f0f0209927ad395eed49c 452 Gene3D G3DSA:3.30.310.50 368 448 4.2E-18 T 10-11-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS16775 320c8e6a260f0f0209927ad395eed49c 452 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 263 373 7.4E-32 T 10-11-2016 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS16775 320c8e6a260f0f0209927ad395eed49c 452 SUPERFAMILY SSF53738 163 260 3.37E-28 T 10-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS16775 320c8e6a260f0f0209927ad395eed49c 452 SUPERFAMILY SSF53738 4 185 1.02E-42 T 10-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS16775 320c8e6a260f0f0209927ad395eed49c 452 Gene3D G3DSA:3.40.120.10 256 367 3.7E-33 T 10-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS16775 320c8e6a260f0f0209927ad395eed49c 452 Gene3D G3DSA:3.40.120.10 181 255 2.7E-25 T 10-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS16775 320c8e6a260f0f0209927ad395eed49c 452 SUPERFAMILY SSF53738 263 369 4.32E-30 T 10-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS16775 320c8e6a260f0f0209927ad395eed49c 452 Gene3D G3DSA:3.40.120.10 4 156 4.1E-41 T 10-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS16775 320c8e6a260f0f0209927ad395eed49c 452 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 164 259 4.5E-20 T 10-11-2016 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS12540 07d37cc796d28095847f13beaa0ecb37 258 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 5 258 3.3E-114 T 10-11-2016 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 A4G23_RS12540 07d37cc796d28095847f13beaa0ecb37 258 SUPERFAMILY SSF52540 5 246 2.37E-58 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS12540 07d37cc796d28095847f13beaa0ecb37 258 SMART SM00382 29 229 3.9E-11 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS12540 07d37cc796d28095847f13beaa0ecb37 258 Pfam PF00005 ABC transporter 21 176 1.8E-29 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS12540 07d37cc796d28095847f13beaa0ecb37 258 Gene3D G3DSA:3.40.50.300 3 250 1.2E-65 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS12540 07d37cc796d28095847f13beaa0ecb37 258 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS22095 0bae4f507f169e97d16a5102698a5c30 368 PRINTS PR01270 Histone deacetylase superfamily signature 138 161 9.8E-15 T 10-11-2016 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A4G23_RS22095 0bae4f507f169e97d16a5102698a5c30 368 PRINTS PR01270 Histone deacetylase superfamily signature 171 186 9.8E-15 T 10-11-2016 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A4G23_RS22095 0bae4f507f169e97d16a5102698a5c30 368 PRINTS PR01270 Histone deacetylase superfamily signature 256 266 9.8E-15 T 10-11-2016 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A4G23_RS22095 0bae4f507f169e97d16a5102698a5c30 368 Pfam PF00850 Histone deacetylase domain 48 312 1.4E-71 T 10-11-2016 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A4G23_RS22095 0bae4f507f169e97d16a5102698a5c30 368 Gene3D G3DSA:3.40.800.20 4 334 2.0E-85 T 10-11-2016 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A4G23_RS22095 0bae4f507f169e97d16a5102698a5c30 368 SUPERFAMILY SSF52768 4 363 2.21E-89 T 10-11-2016 A4G23_RS13910 36e1fa4e7405fe5bba95adfba3b26c13 301 Pfam PF10977 Protein of unknown function (DUF2797) 33 282 5.7E-22 T 10-11-2016 IPR021246 Protein of unknown function DUF2797 A4G23_RS24240 bc252ec178bb46df7f41daf93cea3542 163 Pfam PF00293 NUDIX domain 18 130 8.0E-17 T 10-11-2016 IPR000086 NUDIX hydrolase domain GO:0016787 A4G23_RS24240 bc252ec178bb46df7f41daf93cea3542 163 SUPERFAMILY SSF55811 14 141 4.06E-24 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS24240 bc252ec178bb46df7f41daf93cea3542 163 PRINTS PR00502 NUDIX hydrolase family signature 42 56 4.0E-5 T 10-11-2016 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A4G23_RS24240 bc252ec178bb46df7f41daf93cea3542 163 PRINTS PR00502 NUDIX hydrolase family signature 58 73 4.0E-5 T 10-11-2016 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A4G23_RS24240 bc252ec178bb46df7f41daf93cea3542 163 Gene3D G3DSA:3.90.79.10 16 145 4.8E-23 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS27285 319485ac028c6206a3a490c2cc5d277c 100 Gene3D G3DSA:1.10.260.40 8 76 2.6E-25 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS27285 319485ac028c6206a3a490c2cc5d277c 100 SUPERFAMILY SSF47413 8 78 5.33E-15 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS27285 319485ac028c6206a3a490c2cc5d277c 100 Pfam PF13560 Helix-turn-helix domain 16 72 7.6E-9 T 10-11-2016 A4G23_RS27285 319485ac028c6206a3a490c2cc5d277c 100 SMART SM00530 20 74 3.3E-7 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS18340 e33667ceae507eeaeb0676c893ad1f4b 165 SUPERFAMILY SSF88659 106 156 1.65E-5 T 10-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS18340 e33667ceae507eeaeb0676c893ad1f4b 165 Gene3D G3DSA:1.10.10.10 108 156 3.2E-5 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS09635 63e02e52dfde21fc0bc16161877c9cfa 752 Gene3D G3DSA:1.10.150.120 622 701 2.3E-29 T 10-11-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 A4G23_RS09635 63e02e52dfde21fc0bc16161877c9cfa 752 SUPERFAMILY SSF54292 547 634 6.16E-18 T 10-11-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A4G23_RS09635 63e02e52dfde21fc0bc16161877c9cfa 752 Pfam PF01799 [2Fe-2S] binding domain 620 692 1.2E-23 T 10-11-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 A4G23_RS09635 63e02e52dfde21fc0bc16161877c9cfa 752 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 586 594 - T 10-11-2016 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 A4G23_RS09635 63e02e52dfde21fc0bc16161877c9cfa 752 Gene3D G3DSA:3.10.20.30 548 621 1.1E-24 T 10-11-2016 IPR012675 Beta-grasp domain A4G23_RS09635 63e02e52dfde21fc0bc16161877c9cfa 752 SUPERFAMILY SSF47741 631 699 1.96E-26 T 10-11-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 A4G23_RS01090 0817aa70b763468c2a4606fb8b7598f1 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 4.3E-9 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS01090 0817aa70b763468c2a4606fb8b7598f1 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 4.3E-9 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS01090 0817aa70b763468c2a4606fb8b7598f1 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 4.3E-9 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS01090 0817aa70b763468c2a4606fb8b7598f1 249 Pfam PF00106 short chain dehydrogenase 14 205 5.8E-45 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS01090 0817aa70b763468c2a4606fb8b7598f1 249 Gene3D G3DSA:3.40.50.720 8 241 3.1E-60 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS01090 0817aa70b763468c2a4606fb8b7598f1 249 SUPERFAMILY SSF51735 8 241 1.11E-59 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS01090 0817aa70b763468c2a4606fb8b7598f1 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 3.6E-24 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS01090 0817aa70b763468c2a4606fb8b7598f1 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 3.6E-24 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS01090 0817aa70b763468c2a4606fb8b7598f1 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 3.6E-24 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS01090 0817aa70b763468c2a4606fb8b7598f1 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 3.6E-24 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS01090 0817aa70b763468c2a4606fb8b7598f1 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 3.6E-24 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS01090 0817aa70b763468c2a4606fb8b7598f1 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 3.6E-24 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS01650 391a29ef4ffb47f007df8ff8a4cafeac 345 Gene3D G3DSA:3.40.50.2300 184 318 9.6E-33 T 10-11-2016 A4G23_RS01650 391a29ef4ffb47f007df8ff8a4cafeac 345 SMART SM00354 7 77 2.1E-20 T 10-11-2016 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4G23_RS01650 391a29ef4ffb47f007df8ff8a4cafeac 345 Gene3D G3DSA:3.40.50.2300 58 183 2.3E-24 T 10-11-2016 A4G23_RS01650 391a29ef4ffb47f007df8ff8a4cafeac 345 Pfam PF00356 Bacterial regulatory proteins, lacI family 9 54 1.2E-15 T 10-11-2016 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4G23_RS01650 391a29ef4ffb47f007df8ff8a4cafeac 345 Gene3D G3DSA:1.10.260.40 7 57 5.1E-23 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS01650 391a29ef4ffb47f007df8ff8a4cafeac 345 SUPERFAMILY SSF53822 82 322 8.58E-49 T 10-11-2016 IPR028082 Periplasmic binding protein-like I A4G23_RS01650 391a29ef4ffb47f007df8ff8a4cafeac 345 Pfam PF13377 Periplasmic binding protein-like domain 179 337 6.8E-33 T 10-11-2016 A4G23_RS01650 391a29ef4ffb47f007df8ff8a4cafeac 345 SUPERFAMILY SSF47413 7 64 5.06E-16 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS01470 4ae519fe49141fb0d08854efd385c4a5 350 SUPERFAMILY SSF117396 4 291 1.28E-67 T 10-11-2016 IPR002763 Protein of unknown function DUF72 A4G23_RS01470 4ae519fe49141fb0d08854efd385c4a5 350 Pfam PF01904 Protein of unknown function DUF72 22 287 6.1E-57 T 10-11-2016 IPR002763 Protein of unknown function DUF72 A4G23_RS01470 4ae519fe49141fb0d08854efd385c4a5 350 Gene3D G3DSA:3.20.20.410 4 299 7.8E-86 T 10-11-2016 IPR002763 Protein of unknown function DUF72 A4G23_RS02115 a2dab3655e4eadff61a732a1adcb5ac9 236 Pfam PF13489 Methyltransferase domain 26 198 2.0E-16 T 10-11-2016 A4G23_RS02115 a2dab3655e4eadff61a732a1adcb5ac9 236 SUPERFAMILY SSF53335 24 215 1.89E-33 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS02115 a2dab3655e4eadff61a732a1adcb5ac9 236 Gene3D G3DSA:3.40.50.150 23 235 9.4E-33 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS07745 9096f271f038e30335a32d3eb7942b96 211 Pfam PF04203 Sortase family 68 207 2.6E-18 T 10-11-2016 IPR005754 Sortase family A4G23_RS07745 9096f271f038e30335a32d3eb7942b96 211 SUPERFAMILY SSF63817 59 208 1.33E-16 T 10-11-2016 IPR023365 Sortase domain A4G23_RS07745 9096f271f038e30335a32d3eb7942b96 211 Gene3D G3DSA:2.40.260.10 68 188 3.8E-7 T 10-11-2016 IPR023365 Sortase domain A4G23_RS08345 29b3b2614f72ae484847a19c042360e7 382 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 198 380 1.8E-29 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS08345 29b3b2614f72ae484847a19c042360e7 382 SMART SM00331 171 380 2.5E-11 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS24950 387439fa14a3a2f8830b50e1a6f95f40 399 Gene3D G3DSA:3.60.15.10 83 366 1.8E-101 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS24950 387439fa14a3a2f8830b50e1a6f95f40 399 Pfam PF12706 Beta-lactamase superfamily domain 117 316 4.5E-49 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS24950 387439fa14a3a2f8830b50e1a6f95f40 399 SUPERFAMILY SSF56281 203 353 1.57E-34 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS24950 387439fa14a3a2f8830b50e1a6f95f40 399 SUPERFAMILY SSF56281 99 176 1.57E-34 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS22780 0fec09e215d37ccd0fd0e778ff439b5c 452 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 327 2.5E-11 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS22780 0fec09e215d37ccd0fd0e778ff439b5c 452 SUPERFAMILY SSF51905 76 396 7.56E-29 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS22780 0fec09e215d37ccd0fd0e778ff439b5c 452 SUPERFAMILY SSF51905 7 48 7.56E-29 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS22780 0fec09e215d37ccd0fd0e778ff439b5c 452 Gene3D G3DSA:3.50.50.60 205 309 6.6E-7 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS22780 0fec09e215d37ccd0fd0e778ff439b5c 452 Gene3D G3DSA:3.50.50.60 6 204 1.6E-23 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS22780 0fec09e215d37ccd0fd0e778ff439b5c 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 302 316 3.1E-7 T 10-11-2016 A4G23_RS22780 0fec09e215d37ccd0fd0e778ff439b5c 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 199 224 3.1E-7 T 10-11-2016 A4G23_RS22780 0fec09e215d37ccd0fd0e778ff439b5c 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 3.1E-7 T 10-11-2016 A4G23_RS22780 0fec09e215d37ccd0fd0e778ff439b5c 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 199 217 1.7E-8 T 10-11-2016 A4G23_RS22780 0fec09e215d37ccd0fd0e778ff439b5c 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 301 317 1.7E-8 T 10-11-2016 A4G23_RS22780 0fec09e215d37ccd0fd0e778ff439b5c 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 1.7E-8 T 10-11-2016 A4G23_RS13060 5dcabbb8130e17a37dbf8faa2be4da42 539 Pfam PF08264 Anticodon-binding domain of tRNA 405 496 3.0E-6 T 10-11-2016 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 A4G23_RS13060 5dcabbb8130e17a37dbf8faa2be4da42 539 Gene3D G3DSA:2.170.220.10 129 241 1.2E-44 T 10-11-2016 A4G23_RS13060 5dcabbb8130e17a37dbf8faa2be4da42 539 PRINTS PR01041 Methionyl-tRNA synthetase signature 51 65 4.0E-32 T 10-11-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A4G23_RS13060 5dcabbb8130e17a37dbf8faa2be4da42 539 PRINTS PR01041 Methionyl-tRNA synthetase signature 272 287 4.0E-32 T 10-11-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A4G23_RS13060 5dcabbb8130e17a37dbf8faa2be4da42 539 PRINTS PR01041 Methionyl-tRNA synthetase signature 240 251 4.0E-32 T 10-11-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A4G23_RS13060 5dcabbb8130e17a37dbf8faa2be4da42 539 PRINTS PR01041 Methionyl-tRNA synthetase signature 364 375 4.0E-32 T 10-11-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A4G23_RS13060 5dcabbb8130e17a37dbf8faa2be4da42 539 PRINTS PR01041 Methionyl-tRNA synthetase signature 19 32 4.0E-32 T 10-11-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A4G23_RS13060 5dcabbb8130e17a37dbf8faa2be4da42 539 PRINTS PR01041 Methionyl-tRNA synthetase signature 100 111 4.0E-32 T 10-11-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A4G23_RS13060 5dcabbb8130e17a37dbf8faa2be4da42 539 Gene3D G3DSA:1.10.730.10 353 532 4.4E-50 T 10-11-2016 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4G23_RS13060 5dcabbb8130e17a37dbf8faa2be4da42 539 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 17 498 3.6E-149 T 10-11-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A4G23_RS13060 5dcabbb8130e17a37dbf8faa2be4da42 539 SUPERFAMILY SSF47323 365 532 2.8E-36 T 10-11-2016 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4G23_RS13060 5dcabbb8130e17a37dbf8faa2be4da42 539 Pfam PF09334 tRNA synthetases class I (M) 17 376 3.3E-106 T 10-11-2016 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4G23_RS13060 5dcabbb8130e17a37dbf8faa2be4da42 539 SUPERFAMILY SSF52374 15 361 3.75E-105 T 10-11-2016 A4G23_RS13060 5dcabbb8130e17a37dbf8faa2be4da42 539 Gene3D G3DSA:3.40.50.620 15 126 8.1E-67 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS13060 5dcabbb8130e17a37dbf8faa2be4da42 539 Gene3D G3DSA:3.40.50.620 242 350 8.1E-67 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS13060 5dcabbb8130e17a37dbf8faa2be4da42 539 Hamap MF_01228 Methionine--tRNA ligase [metG]. 6 526 46.542 T 10-11-2016 IPR023457 Methionine-tRNA synthetase, type 2 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A4G23_RS00870 29b338e43e626d418d2897765f512ed4 534 Gene3D G3DSA:3.40.605.10 9 266 6.9E-42 T 10-11-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A4G23_RS00870 29b338e43e626d418d2897765f512ed4 534 Gene3D G3DSA:3.40.309.10 269 455 2.0E-48 T 10-11-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 A4G23_RS00870 29b338e43e626d418d2897765f512ed4 534 Pfam PF00171 Aldehyde dehydrogenase family 37 458 9.1E-48 T 10-11-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A4G23_RS00870 29b338e43e626d418d2897765f512ed4 534 SUPERFAMILY SSF53720 26 519 1.96E-95 T 10-11-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A4G23_RS15810 27b5a26139a37364773a033faed1b081 545 Gene3D G3DSA:1.20.1250.20 5 183 9.3E-27 T 10-11-2016 A4G23_RS15810 27b5a26139a37364773a033faed1b081 545 Gene3D G3DSA:1.20.1250.20 496 519 3.9E-19 T 10-11-2016 A4G23_RS15810 27b5a26139a37364773a033faed1b081 545 Gene3D G3DSA:1.20.1250.20 274 429 3.9E-19 T 10-11-2016 A4G23_RS15810 27b5a26139a37364773a033faed1b081 545 PRINTS PR01036 Tetracycline resistance protein TetB signature 69 91 6.6E-10 T 10-11-2016 A4G23_RS15810 27b5a26139a37364773a033faed1b081 545 PRINTS PR01036 Tetracycline resistance protein TetB signature 131 155 6.6E-10 T 10-11-2016 A4G23_RS15810 27b5a26139a37364773a033faed1b081 545 PRINTS PR01036 Tetracycline resistance protein TetB signature 156 180 6.6E-10 T 10-11-2016 A4G23_RS15810 27b5a26139a37364773a033faed1b081 545 PRINTS PR01036 Tetracycline resistance protein TetB signature 9 33 6.6E-10 T 10-11-2016 A4G23_RS15810 27b5a26139a37364773a033faed1b081 545 PRINTS PR01036 Tetracycline resistance protein TetB signature 101 121 6.6E-10 T 10-11-2016 A4G23_RS15810 27b5a26139a37364773a033faed1b081 545 Pfam PF07690 Major Facilitator Superfamily 12 418 6.0E-47 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS15810 27b5a26139a37364773a033faed1b081 545 SUPERFAMILY SSF103473 256 428 2.75E-59 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS15810 27b5a26139a37364773a033faed1b081 545 SUPERFAMILY SSF103473 495 519 2.75E-59 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS15810 27b5a26139a37364773a033faed1b081 545 SUPERFAMILY SSF103473 2 189 2.75E-59 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS00175 cd61c5eee63f06ce73121cf204584e05 860 Gene3D G3DSA:2.60.40.290 757 859 1.9E-35 T 10-11-2016 IPR012291 Cellulose-binding family II/chitobiase, carbohydrate-binding domain GO:0004553|GO:0030247 A4G23_RS00175 cd61c5eee63f06ce73121cf204584e05 860 Gene3D G3DSA:2.60.40.10 176 265 8.4E-26 T 10-11-2016 IPR013783 Immunoglobulin-like fold A4G23_RS00175 cd61c5eee63f06ce73121cf204584e05 860 Pfam PF02018 Carbohydrate binding domain 28 148 4.0E-13 T 10-11-2016 IPR003305 Carbohydrate-binding, CenC-like GO:0016798 A4G23_RS00175 cd61c5eee63f06ce73121cf204584e05 860 Pfam PF00553 Cellulose binding domain 758 857 3.8E-30 T 10-11-2016 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 A4G23_RS00175 cd61c5eee63f06ce73121cf204584e05 860 SUPERFAMILY SSF49785 25 164 2.21E-35 T 10-11-2016 IPR008979 Galactose-binding domain-like A4G23_RS00175 cd61c5eee63f06ce73121cf204584e05 860 SUPERFAMILY SSF49384 754 859 2.51E-31 T 10-11-2016 IPR008965 Carbohydrate-binding domain GO:0030246 A4G23_RS00175 cd61c5eee63f06ce73121cf204584e05 860 SUPERFAMILY SSF48208 268 744 5.53E-128 T 10-11-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 A4G23_RS00175 cd61c5eee63f06ce73121cf204584e05 860 Gene3D G3DSA:2.60.120.260 28 164 3.9E-36 T 10-11-2016 IPR008979 Galactose-binding domain-like A4G23_RS00175 cd61c5eee63f06ce73121cf204584e05 860 Pfam PF02927 Cellulase N-terminal ig-like domain 176 258 5.0E-22 T 10-11-2016 IPR004197 Cellulase, Ig-like domain GO:0005975|GO:0008810 A4G23_RS00175 cd61c5eee63f06ce73121cf204584e05 860 ProSitePatterns PS00561 CBM2a (carbohydrate-binding type-2) domain signature. 822 835 - T 10-11-2016 IPR018366 Carbohydrate-binding type-2, conserved site GO:0004553|GO:0005975|GO:0030246 A4G23_RS00175 cd61c5eee63f06ce73121cf204584e05 860 Pfam PF00759 Glycosyl hydrolase family 9 269 738 1.5E-100 T 10-11-2016 IPR001701 Glycoside hydrolase family 9 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 A4G23_RS00175 cd61c5eee63f06ce73121cf204584e05 860 SUPERFAMILY SSF81296 178 266 2.8E-19 T 10-11-2016 IPR014756 Immunoglobulin E-set A4G23_RS00175 cd61c5eee63f06ce73121cf204584e05 860 Gene3D G3DSA:1.50.10.10 268 745 2.4E-153 T 10-11-2016 IPR012341 Six-hairpin glycosidase GO:0003824 A4G23_RS00175 cd61c5eee63f06ce73121cf204584e05 860 ProSitePatterns PS00698 Glycosyl hydrolases family 9 active sites signature 2. 715 733 - T 10-11-2016 IPR033126 Glycosyl hydrolases family 9, Asp/Glu active sites KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 A4G23_RS00175 cd61c5eee63f06ce73121cf204584e05 860 SMART SM00637 758 857 1.5E-41 T 10-11-2016 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 A4G23_RS24330 9c1ebe463c4e0f13eda51003b52b6f57 187 Pfam PF01814 Hemerythrin HHE cation binding domain 7 125 1.3E-15 T 10-11-2016 IPR012312 Haemerythrin-like Reactome: R-HSA-390471 A4G23_RS24330 9c1ebe463c4e0f13eda51003b52b6f57 187 Gene3D G3DSA:1.20.120.520 15 143 8.2E-14 T 10-11-2016 A4G23_RS14200 67b0e592214a1bdc3daf09874a4afdd0 105 Gene3D G3DSA:1.10.1660.10 21 101 8.4E-13 T 10-11-2016 A4G23_RS14200 67b0e592214a1bdc3daf09874a4afdd0 105 SUPERFAMILY SSF46955 21 103 2.98E-11 T 10-11-2016 IPR009061 Putative DNA-binding domain A4G23_RS14200 67b0e592214a1bdc3daf09874a4afdd0 105 Pfam PF13411 MerR HTH family regulatory protein 21 84 1.8E-9 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS14200 67b0e592214a1bdc3daf09874a4afdd0 105 SMART SM00422 21 89 4.6E-6 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS21120 9784ef45d27833f4329903cb12e5aa7e 1541 Pfam PF08494 DEAD/H associated 667 876 1.7E-76 T 10-11-2016 IPR013701 DEAD/H associated GO:0005524|GO:0016818 A4G23_RS21120 9784ef45d27833f4329903cb12e5aa7e 1541 Pfam PF00271 Helicase conserved C-terminal domain 278 403 2.3E-11 T 10-11-2016 IPR001650 Helicase, C-terminal A4G23_RS21120 9784ef45d27833f4329903cb12e5aa7e 1541 SMART SM00490 291 403 6.1E-13 T 10-11-2016 IPR001650 Helicase, C-terminal A4G23_RS21120 9784ef45d27833f4329903cb12e5aa7e 1541 SUPERFAMILY SSF52540 334 410 9.07E-48 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS21120 9784ef45d27833f4329903cb12e5aa7e 1541 SUPERFAMILY SSF52540 34 210 9.07E-48 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS21120 9784ef45d27833f4329903cb12e5aa7e 1541 SUPERFAMILY SSF52540 260 303 9.07E-48 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS21120 9784ef45d27833f4329903cb12e5aa7e 1541 SMART SM00487 20 239 4.6E-36 T 10-11-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4G23_RS21120 9784ef45d27833f4329903cb12e5aa7e 1541 Gene3D G3DSA:3.40.50.300 9 214 3.3E-43 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS21120 9784ef45d27833f4329903cb12e5aa7e 1541 Pfam PF00270 DEAD/DEAH box helicase 25 208 1.2E-26 T 10-11-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A4G23_RS21120 9784ef45d27833f4329903cb12e5aa7e 1541 Gene3D G3DSA:3.40.50.300 270 432 8.5E-28 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS25635 51676c748d26a0ba6e22ed0b93935cf2 109 PIRSF PIRSF001658 2 109 1.3E-33 T 10-11-2016 IPR000833 Alpha-amylase inhibitor GO:0015066 A4G23_RS25635 51676c748d26a0ba6e22ed0b93935cf2 109 ProDom PD009058 INHIBITOR ALPHA-AMYLASE DIRECT SEQUENCING PAIM MICROBES PIG PANCREATIC I PROTEINACEOUS 40 103 2.0E-6 T 10-11-2016 IPR000833 Alpha-amylase inhibitor GO:0015066 A4G23_RS25635 51676c748d26a0ba6e22ed0b93935cf2 109 Pfam PF01356 Alpha amylase inhibitor 38 103 4.0E-29 T 10-11-2016 IPR000833 Alpha-amylase inhibitor GO:0015066 A4G23_RS25635 51676c748d26a0ba6e22ed0b93935cf2 109 Gene3D G3DSA:2.60.40.20 36 104 1.4E-30 T 10-11-2016 IPR000833 Alpha-amylase inhibitor GO:0015066 A4G23_RS25635 51676c748d26a0ba6e22ed0b93935cf2 109 SUPERFAMILY SSF49498 36 103 2.75E-26 T 10-11-2016 IPR000833 Alpha-amylase inhibitor GO:0015066 A4G23_RS25635 51676c748d26a0ba6e22ed0b93935cf2 109 SMART SM00783 35 103 1.1E-32 T 10-11-2016 IPR000833 Alpha-amylase inhibitor GO:0015066 A4G23_RS16825 b43effcb9c3e7ccad862edf13702a13d 224 SUPERFAMILY SSF141571 37 191 3.27E-26 T 10-11-2016 A4G23_RS16825 b43effcb9c3e7ccad862edf13702a13d 224 Pfam PF13599 Pentapeptide repeats (9 copies) 115 189 7.4E-10 T 10-11-2016 IPR001646 Pentapeptide repeat A4G23_RS18800 e618a00566d480da40c269bca4e4fa9d 296 SUPERFAMILY SSF69572 28 261 2.75E-11 T 10-11-2016 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 A4G23_RS18800 e618a00566d480da40c269bca4e4fa9d 296 TIGRFAM TIGR03882 cyclo_dehyd_2: bacteriocin biosynthesis cyclodehydratase domain 149 269 1.3E-10 T 10-11-2016 IPR022291 Bacteriocin biosynthesis, cyclodehydratase domain A4G23_RS18800 e618a00566d480da40c269bca4e4fa9d 296 Pfam PF00899 ThiF family 24 261 4.2E-14 T 10-11-2016 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 A4G23_RS18800 e618a00566d480da40c269bca4e4fa9d 296 Gene3D G3DSA:3.40.50.720 29 93 3.6E-5 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS17815 74e992e2aafb4eb7ad981b432b3c3e01 279 Gene3D G3DSA:1.10.260.40 21 78 1.0E-12 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS17815 74e992e2aafb4eb7ad981b432b3c3e01 279 SMART SM00530 24 79 1.0E-9 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS17815 74e992e2aafb4eb7ad981b432b3c3e01 279 Pfam PF13560 Helix-turn-helix domain 22 81 5.5E-10 T 10-11-2016 A4G23_RS17815 74e992e2aafb4eb7ad981b432b3c3e01 279 SUPERFAMILY SSF47413 17 78 2.39E-13 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS01710 aa23d0186f7be4d57b77f49efcad9ea4 202 Pfam PF00005 ABC transporter 16 144 1.3E-27 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS01710 aa23d0186f7be4d57b77f49efcad9ea4 202 SMART SM00382 25 199 9.9E-10 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS01710 aa23d0186f7be4d57b77f49efcad9ea4 202 Gene3D G3DSA:3.40.50.300 1 197 1.8E-51 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS01710 aa23d0186f7be4d57b77f49efcad9ea4 202 SUPERFAMILY SSF52540 1 197 4.51E-51 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS24510 a782d91d683828398e5b4ab098861428 276 Pfam PF13560 Helix-turn-helix domain 11 71 3.7E-13 T 10-11-2016 A4G23_RS24510 a782d91d683828398e5b4ab098861428 276 Gene3D G3DSA:1.10.260.40 10 67 1.9E-13 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS24510 a782d91d683828398e5b4ab098861428 276 SMART SM00530 13 68 5.1E-12 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS24510 a782d91d683828398e5b4ab098861428 276 SUPERFAMILY SSF47413 9 67 1.05E-13 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS23950 368b9a761f44f097e8ac451e9ede5c91 299 SMART SM00382 40 233 3.8E-12 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS23950 368b9a761f44f097e8ac451e9ede5c91 299 SUPERFAMILY SSF52540 14 243 2.46E-55 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS23950 368b9a761f44f097e8ac451e9ede5c91 299 Gene3D G3DSA:3.40.50.300 8 247 1.1E-55 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS23950 368b9a761f44f097e8ac451e9ede5c91 299 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS23950 368b9a761f44f097e8ac451e9ede5c91 299 Pfam PF00005 ABC transporter 31 185 1.2E-27 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS12065 9f6da2e5576d992c9380afac97592c86 599 SMART SM00091 212 282 6.8E-6 T 10-11-2016 IPR000014 PAS domain A4G23_RS12065 9f6da2e5576d992c9380afac97592c86 599 Gene3D G3DSA:3.30.450.20 204 321 4.8E-19 T 10-11-2016 A4G23_RS12065 9f6da2e5576d992c9380afac97592c86 599 SMART SM00065 29 194 0.0017 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS12065 9f6da2e5576d992c9380afac97592c86 599 SMART SM00267 448 597 2.0E-26 T 10-11-2016 IPR000160 GGDEF domain A4G23_RS12065 9f6da2e5576d992c9380afac97592c86 599 Pfam PF13426 PAS domain 233 321 4.0E-7 T 10-11-2016 IPR000014 PAS domain A4G23_RS12065 9f6da2e5576d992c9380afac97592c86 599 Gene3D G3DSA:3.30.70.270 337 362 7.8E-44 T 10-11-2016 A4G23_RS12065 9f6da2e5576d992c9380afac97592c86 599 Gene3D G3DSA:3.30.70.270 467 591 7.8E-44 T 10-11-2016 A4G23_RS12065 9f6da2e5576d992c9380afac97592c86 599 SUPERFAMILY SSF55785 200 320 5.76E-18 T 10-11-2016 IPR000014 PAS domain A4G23_RS12065 9f6da2e5576d992c9380afac97592c86 599 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 208 330 2.5E-14 T 10-11-2016 IPR000014 PAS domain A4G23_RS12065 9f6da2e5576d992c9380afac97592c86 599 SMART SM00086 282 324 3.7E-4 T 10-11-2016 IPR001610 PAC motif A4G23_RS12065 9f6da2e5576d992c9380afac97592c86 599 SUPERFAMILY SSF55073 469 591 1.83E-35 T 10-11-2016 IPR029787 Nucleotide cyclase A4G23_RS12065 9f6da2e5576d992c9380afac97592c86 599 SUPERFAMILY SSF55781 12 191 3.49E-15 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS12065 9f6da2e5576d992c9380afac97592c86 599 Pfam PF00990 Diguanylate cyclase, GGDEF domain 469 591 8.6E-31 T 10-11-2016 IPR000160 GGDEF domain A4G23_RS12065 9f6da2e5576d992c9380afac97592c86 599 Gene3D G3DSA:3.30.450.40 10 189 1.7E-15 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS12065 9f6da2e5576d992c9380afac97592c86 599 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 468 591 1.1E-29 T 10-11-2016 IPR000160 GGDEF domain A4G23_RS06865 8f9bc999459dcfc06ba184d829adff7b 426 Gene3D G3DSA:3.40.190.10 165 353 1.5E-49 T 10-11-2016 A4G23_RS06865 8f9bc999459dcfc06ba184d829adff7b 426 Gene3D G3DSA:3.40.190.10 45 164 5.4E-6 T 10-11-2016 A4G23_RS06865 8f9bc999459dcfc06ba184d829adff7b 426 Pfam PF13416 Bacterial extracellular solute-binding protein 54 359 1.1E-53 T 10-11-2016 A4G23_RS06865 8f9bc999459dcfc06ba184d829adff7b 426 PRINTS PR00181 Maltose binding protein signature 79 97 6.4E-6 T 10-11-2016 IPR006060 Maltose binding protein GO:0005363|GO:0015768 A4G23_RS06865 8f9bc999459dcfc06ba184d829adff7b 426 PRINTS PR00181 Maltose binding protein signature 246 265 6.4E-6 T 10-11-2016 IPR006060 Maltose binding protein GO:0005363|GO:0015768 A4G23_RS06865 8f9bc999459dcfc06ba184d829adff7b 426 PRINTS PR00181 Maltose binding protein signature 166 185 6.4E-6 T 10-11-2016 IPR006060 Maltose binding protein GO:0005363|GO:0015768 A4G23_RS06865 8f9bc999459dcfc06ba184d829adff7b 426 SUPERFAMILY SSF53850 33 415 8.98E-84 T 10-11-2016 A4G23_RS14180 6443a2937602de326872c7e303adb8dd 448 Pfam PF01494 FAD binding domain 37 102 1.3E-5 T 10-11-2016 IPR002938 FAD-binding domain GO:0071949 A4G23_RS14180 6443a2937602de326872c7e303adb8dd 448 Pfam PF01494 FAD binding domain 215 390 2.3E-11 T 10-11-2016 IPR002938 FAD-binding domain GO:0071949 A4G23_RS14180 6443a2937602de326872c7e303adb8dd 448 SUPERFAMILY SSF51905 34 171 2.16E-49 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS14180 6443a2937602de326872c7e303adb8dd 448 SUPERFAMILY SSF51905 332 423 2.16E-49 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS14180 6443a2937602de326872c7e303adb8dd 448 SUPERFAMILY SSF51905 206 233 2.16E-49 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS14180 6443a2937602de326872c7e303adb8dd 448 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 213 228 6.4E-21 T 10-11-2016 A4G23_RS14180 6443a2937602de326872c7e303adb8dd 448 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 37 59 6.4E-21 T 10-11-2016 A4G23_RS14180 6443a2937602de326872c7e303adb8dd 448 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 352 368 6.4E-21 T 10-11-2016 A4G23_RS14180 6443a2937602de326872c7e303adb8dd 448 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 337 352 6.4E-21 T 10-11-2016 A4G23_RS14180 6443a2937602de326872c7e303adb8dd 448 Gene3D G3DSA:3.50.50.60 205 239 6.2E-35 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS14180 6443a2937602de326872c7e303adb8dd 448 Gene3D G3DSA:3.50.50.60 37 173 6.2E-35 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS14180 6443a2937602de326872c7e303adb8dd 448 Gene3D G3DSA:3.50.50.60 325 399 6.2E-35 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS19850 35df8ac2a6549ce08ac4406f7e32db50 895 Pfam PF11897 Protein of unknown function (DUF3417) 13 141 7.5E-33 T 10-11-2016 IPR024517 Glycogen phosphorylase, domain of unknown function DUF3417 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 A4G23_RS19850 35df8ac2a6549ce08ac4406f7e32db50 895 TIGRFAM TIGR02094 more_P_ylases: alpha-glucan phosphorylases 128 740 1.1E-231 T 10-11-2016 IPR011834 Alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 A4G23_RS19850 35df8ac2a6549ce08ac4406f7e32db50 895 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 628 640 - T 10-11-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 A4G23_RS19850 35df8ac2a6549ce08ac4406f7e32db50 895 Gene3D G3DSA:3.40.50.2000 446 744 1.4E-91 T 10-11-2016 A4G23_RS19850 35df8ac2a6549ce08ac4406f7e32db50 895 SUPERFAMILY SSF53756 4 769 1.18E-194 T 10-11-2016 A4G23_RS19850 35df8ac2a6549ce08ac4406f7e32db50 895 Gene3D G3DSA:3.40.50.2000 24 445 3.0E-88 T 10-11-2016 A4G23_RS19850 35df8ac2a6549ce08ac4406f7e32db50 895 Pfam PF00343 Carbohydrate phosphorylase 292 650 4.8E-16 T 10-11-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 A4G23_RS19850 35df8ac2a6549ce08ac4406f7e32db50 895 Pfam PF00343 Carbohydrate phosphorylase 146 191 2.9E-6 T 10-11-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 A4G23_RS19850 35df8ac2a6549ce08ac4406f7e32db50 895 PIRSF PIRSF000460 1 823 6.0E-251 T 10-11-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 A4G23_RS05715 0a50a3e35435069312564a99aa3f468d 229 SUPERFAMILY SSF55718 148 228 1.88E-18 T 10-11-2016 IPR003033 SCP2 sterol-binding domain A4G23_RS05715 0a50a3e35435069312564a99aa3f468d 229 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 11 210 2.0E-40 T 10-11-2016 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type A4G23_RS05715 0a50a3e35435069312564a99aa3f468d 229 Pfam PF07398 MDMPI C-terminal domain 148 227 1.4E-7 T 10-11-2016 IPR010872 MDMPI C-terminal A4G23_RS05715 0a50a3e35435069312564a99aa3f468d 229 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 12 140 1.4E-21 T 10-11-2016 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 A4G23_RS05715 0a50a3e35435069312564a99aa3f468d 229 SUPERFAMILY SSF109854 1 146 1.03E-37 T 10-11-2016 A4G23_RS05715 0a50a3e35435069312564a99aa3f468d 229 Gene3D G3DSA:1.20.120.450 9 136 7.8E-6 T 10-11-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase A4G23_RS05820 a26a9e32cf0eb46d583ee62e8567ac48 123 SMART SM00028 43 76 61.0 T 10-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 A4G23_RS05820 a26a9e32cf0eb46d583ee62e8567ac48 123 SMART SM00028 77 110 0.6 T 10-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 A4G23_RS05820 a26a9e32cf0eb46d583ee62e8567ac48 123 Pfam PF14559 Tetratricopeptide repeat 19 76 1.1E-6 T 10-11-2016 A4G23_RS05820 a26a9e32cf0eb46d583ee62e8567ac48 123 Pfam PF07719 Tetratricopeptide repeat 77 109 1.0E-5 T 10-11-2016 IPR013105 Tetratricopeptide repeat 2 A4G23_RS05820 a26a9e32cf0eb46d583ee62e8567ac48 123 SUPERFAMILY SSF48452 6 111 2.78E-17 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS05820 a26a9e32cf0eb46d583ee62e8567ac48 123 Gene3D G3DSA:1.25.40.10 2 109 5.5E-17 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS17625 c6a558d11a44cd9d9a25bf12419a9a35 414 ProSitePatterns PS00216 Sugar transport proteins signature 1. 83 99 - T 10-11-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A4G23_RS17625 c6a558d11a44cd9d9a25bf12419a9a35 414 Pfam PF07690 Major Facilitator Superfamily 34 340 1.9E-29 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS17625 c6a558d11a44cd9d9a25bf12419a9a35 414 SUPERFAMILY SSF103473 13 403 1.44E-55 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS17625 c6a558d11a44cd9d9a25bf12419a9a35 414 Gene3D G3DSA:1.20.1250.20 28 208 1.1E-26 T 10-11-2016 A4G23_RS17625 c6a558d11a44cd9d9a25bf12419a9a35 414 Gene3D G3DSA:1.20.1250.20 230 409 6.3E-11 T 10-11-2016 A4G23_RS21285 e0de457c076f7ea77ca934d4ee2f0fec 268 Gene3D G3DSA:1.10.10.10 62 127 2.3E-32 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS21285 e0de457c076f7ea77ca934d4ee2f0fec 268 SUPERFAMILY SSF46785 62 127 4.2E-20 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS21285 e0de457c076f7ea77ca934d4ee2f0fec 268 Gene3D G3DSA:2.10.109.10 149 267 7.7E-45 T 10-11-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain A4G23_RS21285 e0de457c076f7ea77ca934d4ee2f0fec 268 TIGRFAM TIGR00498 lexA: repressor LexA 61 268 2.7E-75 T 10-11-2016 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 A4G23_RS21285 e0de457c076f7ea77ca934d4ee2f0fec 268 Pfam PF01726 LexA DNA binding domain 61 124 1.1E-29 T 10-11-2016 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 A4G23_RS21285 e0de457c076f7ea77ca934d4ee2f0fec 268 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 223 235 2.6E-11 T 10-11-2016 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 A4G23_RS21285 e0de457c076f7ea77ca934d4ee2f0fec 268 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 195 206 2.6E-11 T 10-11-2016 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 A4G23_RS21285 e0de457c076f7ea77ca934d4ee2f0fec 268 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 184 194 2.6E-11 T 10-11-2016 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 A4G23_RS21285 e0de457c076f7ea77ca934d4ee2f0fec 268 Hamap MF_00015 LexA repressor [lexA]. 62 268 34.255 T 10-11-2016 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 A4G23_RS21285 e0de457c076f7ea77ca934d4ee2f0fec 268 Pfam PF00717 Peptidase S24-like 187 251 1.5E-16 T 10-11-2016 IPR019759 Peptidase S24/S26A/S26B A4G23_RS21285 e0de457c076f7ea77ca934d4ee2f0fec 268 SUPERFAMILY SSF51306 148 266 2.27E-36 T 10-11-2016 IPR015927 Peptidase S24/S26A/S26B/S26C A4G23_RS20025 5e1dbde34d663fe369be456a80460f10 387 Pfam PF00266 Aminotransferase class-V 3 370 3.4E-61 T 10-11-2016 IPR000192 Aminotransferase class V domain A4G23_RS20025 5e1dbde34d663fe369be456a80460f10 387 PIRSF PIRSF005572 1 384 1.8E-108 T 10-11-2016 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 A4G23_RS20025 5e1dbde34d663fe369be456a80460f10 387 SUPERFAMILY SSF53383 2 379 1.6E-93 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS20025 5e1dbde34d663fe369be456a80460f10 387 Gene3D G3DSA:3.90.1150.10 252 374 1.8E-39 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS20025 5e1dbde34d663fe369be456a80460f10 387 Gene3D G3DSA:3.40.640.10 14 251 1.4E-72 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS12750 c3f54b29d5568a12a1a5bd2e915c38a5 301 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 128 300 3.7E-44 T 10-11-2016 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 A4G23_RS12750 c3f54b29d5568a12a1a5bd2e915c38a5 301 Gene3D G3DSA:3.40.50.150 129 257 4.5E-11 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS12750 c3f54b29d5568a12a1a5bd2e915c38a5 301 Pfam PF02390 Putative methyltransferase 128 295 7.3E-50 T 10-11-2016 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 A4G23_RS12750 c3f54b29d5568a12a1a5bd2e915c38a5 301 SUPERFAMILY SSF53335 79 299 5.22E-29 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS12750 c3f54b29d5568a12a1a5bd2e915c38a5 301 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 87 301 27.949 T 10-11-2016 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 A4G23_RS22815 06c4dcd8e11478be501b8118dbfc5c2b 315 Pfam PF01867 CRISPR associated protein Cas1 29 127 1.8E-7 T 10-11-2016 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 A4G23_RS22815 06c4dcd8e11478be501b8118dbfc5c2b 315 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 21 279 16.799 T 10-11-2016 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 A4G23_RS22815 06c4dcd8e11478be501b8118dbfc5c2b 315 TIGRFAM TIGR03638 cas1_ECOLI: CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI 14 278 7.3E-105 T 10-11-2016 IPR019851 CRISPR-associated protein Cas1, ECOLI subtype GO:0004520|GO:0043571|GO:0046872 A4G23_RS11090 feae625b92f790670246b55e5a7e9275 139 Gene3D G3DSA:3.10.180.10 18 130 2.2E-14 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS11090 feae625b92f790670246b55e5a7e9275 139 SUPERFAMILY SSF54593 19 129 5.09E-17 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS18895 ee5f5dd95e4cef06c6512f381a222663 266 TIGRFAM TIGR02067 his_9_HisN: histidinol-phosphatase 8 262 1.0E-90 T 10-11-2016 IPR011809 Histidinol-phosphate phosphatase, putative, inositol monophosphatase GO:0004401 KEGG: 00340+3.1.3.15 A4G23_RS18895 ee5f5dd95e4cef06c6512f381a222663 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 62 78 1.4E-12 T 10-11-2016 IPR000760 Inositol monophosphatase GO:0046854 A4G23_RS18895 ee5f5dd95e4cef06c6512f381a222663 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 40 60 1.4E-12 T 10-11-2016 IPR000760 Inositol monophosphatase GO:0046854 A4G23_RS18895 ee5f5dd95e4cef06c6512f381a222663 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 81 97 1.4E-12 T 10-11-2016 IPR000760 Inositol monophosphatase GO:0046854 A4G23_RS18895 ee5f5dd95e4cef06c6512f381a222663 266 SUPERFAMILY SSF56655 3 262 1.83E-75 T 10-11-2016 A4G23_RS18895 ee5f5dd95e4cef06c6512f381a222663 266 Pfam PF00459 Inositol monophosphatase family 8 260 3.5E-46 T 10-11-2016 IPR000760 Inositol monophosphatase GO:0046854 A4G23_RS18895 ee5f5dd95e4cef06c6512f381a222663 266 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 81 94 - T 10-11-2016 IPR020583 Inositol monophosphatase, metal-binding site A4G23_RS18895 ee5f5dd95e4cef06c6512f381a222663 266 Gene3D G3DSA:3.40.190.80 159 262 1.5E-22 T 10-11-2016 A4G23_RS18895 ee5f5dd95e4cef06c6512f381a222663 266 Gene3D G3DSA:3.30.540.10 3 158 1.5E-46 T 10-11-2016 A4G23_RS04175 9f250937b99c7111a26e64e59293bc16 254 SUPERFAMILY SSF48008 120 252 9.68E-19 T 10-11-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal A4G23_RS04175 9f250937b99c7111a26e64e59293bc16 254 SMART SM00895 123 244 4.5E-14 T 10-11-2016 IPR011711 GntR, C-terminal A4G23_RS04175 9f250937b99c7111a26e64e59293bc16 254 Gene3D G3DSA:1.10.10.10 23 90 3.1E-19 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS04175 9f250937b99c7111a26e64e59293bc16 254 SUPERFAMILY SSF46785 18 91 4.61E-17 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS04175 9f250937b99c7111a26e64e59293bc16 254 Gene3D G3DSA:1.20.120.530 120 252 7.1E-16 T 10-11-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal A4G23_RS04175 9f250937b99c7111a26e64e59293bc16 254 Pfam PF00392 Bacterial regulatory proteins, gntR family 25 87 5.1E-14 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS04175 9f250937b99c7111a26e64e59293bc16 254 Pfam PF07729 FCD domain 126 242 7.7E-16 T 10-11-2016 IPR011711 GntR, C-terminal A4G23_RS04175 9f250937b99c7111a26e64e59293bc16 254 SMART SM00345 26 87 4.2E-14 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS04175 9f250937b99c7111a26e64e59293bc16 254 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 59 2.0E-11 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS04175 9f250937b99c7111a26e64e59293bc16 254 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 59 75 2.0E-11 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS08245 4b009393fa82ec4521e4fe58e2039d2d 505 Pfam PF03703 Bacterial PH domain 259 329 1.6E-4 T 10-11-2016 IPR005182 Domain of unknown function DUF304 A4G23_RS08245 4b009393fa82ec4521e4fe58e2039d2d 505 Pfam PF03703 Bacterial PH domain 414 474 8.1E-5 T 10-11-2016 IPR005182 Domain of unknown function DUF304 A4G23_RS08245 4b009393fa82ec4521e4fe58e2039d2d 505 Pfam PF03703 Bacterial PH domain 67 146 8.4E-14 T 10-11-2016 IPR005182 Domain of unknown function DUF304 A4G23_RS08245 4b009393fa82ec4521e4fe58e2039d2d 505 PIRSF PIRSF026631 7 491 4.4E-64 T 10-11-2016 IPR014529 Uncharacterised conserved protein UCP026631 A4G23_RS01445 737abac1e3d58cd64acbe131dc7d9314 261 SUPERFAMILY SSF117396 3 237 3.01E-75 T 10-11-2016 IPR002763 Protein of unknown function DUF72 A4G23_RS01445 737abac1e3d58cd64acbe131dc7d9314 261 Pfam PF01904 Protein of unknown function DUF72 20 237 6.3E-58 T 10-11-2016 IPR002763 Protein of unknown function DUF72 A4G23_RS01445 737abac1e3d58cd64acbe131dc7d9314 261 Gene3D G3DSA:3.20.20.410 3 238 4.4E-74 T 10-11-2016 IPR002763 Protein of unknown function DUF72 A4G23_RS21280 8d1561a3d1947604acbb8809505cf1a1 655 Gene3D G3DSA:3.40.50.300 466 613 6.1E-4 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS21280 8d1561a3d1947604acbb8809505cf1a1 655 Pfam PF13307 Helicase C-terminal domain 471 629 1.7E-26 T 10-11-2016 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 A4G23_RS21280 8d1561a3d1947604acbb8809505cf1a1 655 SMART SM00491 488 617 2.2E-44 T 10-11-2016 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 A4G23_RS21280 8d1561a3d1947604acbb8809505cf1a1 655 SMART SM00487 17 299 7.6E-4 T 10-11-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4G23_RS21280 8d1561a3d1947604acbb8809505cf1a1 655 Gene3D G3DSA:3.40.50.300 394 403 1.8E-21 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS21280 8d1561a3d1947604acbb8809505cf1a1 655 Gene3D G3DSA:3.40.50.300 189 261 1.8E-21 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS21280 8d1561a3d1947604acbb8809505cf1a1 655 Gene3D G3DSA:3.40.50.300 130 131 1.8E-21 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS21280 8d1561a3d1947604acbb8809505cf1a1 655 Gene3D G3DSA:3.40.50.300 22 83 1.8E-21 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS21280 8d1561a3d1947604acbb8809505cf1a1 655 SUPERFAMILY SSF52540 189 260 1.68E-20 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS21280 8d1561a3d1947604acbb8809505cf1a1 655 SUPERFAMILY SSF52540 392 406 1.68E-20 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS21280 8d1561a3d1947604acbb8809505cf1a1 655 SUPERFAMILY SSF52540 445 600 1.68E-20 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS21280 8d1561a3d1947604acbb8809505cf1a1 655 SUPERFAMILY SSF52540 35 85 1.68E-20 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS02105 53978718920c4ed661c75e353dff0894 874 SUPERFAMILY SSF47336 522 565 3.66E-8 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS02105 53978718920c4ed661c75e353dff0894 874 Gene3D G3DSA:3.30.300.30 393 479 1.7E-4 T 10-11-2016 A4G23_RS02105 53978718920c4ed661c75e353dff0894 874 Gene3D G3DSA:3.40.50.980 30 156 4.2E-15 T 10-11-2016 A4G23_RS02105 53978718920c4ed661c75e353dff0894 874 Pfam PF00550 Phosphopantetheine attachment site 522 565 7.4E-8 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS02105 53978718920c4ed661c75e353dff0894 874 SUPERFAMILY SSF56801 30 482 2.22E-77 T 10-11-2016 A4G23_RS02105 53978718920c4ed661c75e353dff0894 874 Gene3D G3DSA:3.40.50.980 157 313 1.5E-25 T 10-11-2016 A4G23_RS02105 53978718920c4ed661c75e353dff0894 874 Gene3D G3DSA:1.10.1200.10 522 566 1.1E-8 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS02105 53978718920c4ed661c75e353dff0894 874 Gene3D G3DSA:2.30.38.10 315 388 1.3E-11 T 10-11-2016 A4G23_RS02105 53978718920c4ed661c75e353dff0894 874 Pfam PF00501 AMP-binding enzyme 30 394 1.4E-45 T 10-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A4G23_RS26480 10418cceac9fcb72a1ded533255609ad 223 SMART SM00257 173 220 3.4E-7 T 10-11-2016 IPR018392 LysM domain A4G23_RS26480 10418cceac9fcb72a1ded533255609ad 223 Pfam PF01476 LysM domain 174 220 1.8E-8 T 10-11-2016 IPR018392 LysM domain A4G23_RS26480 10418cceac9fcb72a1ded533255609ad 223 Gene3D G3DSA:3.10.350.10 173 220 4.0E-9 T 10-11-2016 IPR018392 LysM domain A4G23_RS26480 10418cceac9fcb72a1ded533255609ad 223 SUPERFAMILY SSF54106 173 220 1.23E-6 T 10-11-2016 IPR018392 LysM domain A4G23_RS24915 086ca2ec336a635c71bc9ff86fbee1f4 215 SUPERFAMILY SSF53167 36 179 3.53E-26 T 10-11-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A4G23_RS24915 086ca2ec336a635c71bc9ff86fbee1f4 215 Pfam PF01048 Phosphorylase superfamily 34 175 3.9E-18 T 10-11-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A4G23_RS24915 086ca2ec336a635c71bc9ff86fbee1f4 215 Gene3D G3DSA:3.40.50.1580 35 179 1.5E-22 T 10-11-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A4G23_RS16275 593d7fd3180c68e0976cde586688f82e 410 Gene3D G3DSA:3.20.20.140 90 343 7.9E-54 T 10-11-2016 A4G23_RS16275 593d7fd3180c68e0976cde586688f82e 410 Gene3D G3DSA:2.30.40.10 25 78 2.5E-6 T 10-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4G23_RS16275 593d7fd3180c68e0976cde586688f82e 410 SUPERFAMILY SSF51556 71 353 2.95E-44 T 10-11-2016 IPR032466 Metal-dependent hydrolase A4G23_RS16275 593d7fd3180c68e0976cde586688f82e 410 SUPERFAMILY SSF51338 20 87 1.54E-7 T 10-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4G23_RS12105 c1ed24ce2ad75f7c70dd7a46568ed234 204 Pfam PF00196 Bacterial regulatory proteins, luxR family 142 197 1.5E-18 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS12105 c1ed24ce2ad75f7c70dd7a46568ed234 204 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 185 2.1E-13 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS12105 c1ed24ce2ad75f7c70dd7a46568ed234 204 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 143 157 2.1E-13 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS12105 c1ed24ce2ad75f7c70dd7a46568ed234 204 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 173 2.1E-13 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS12105 c1ed24ce2ad75f7c70dd7a46568ed234 204 Gene3D G3DSA:3.40.50.2300 1 117 2.5E-34 T 10-11-2016 A4G23_RS12105 c1ed24ce2ad75f7c70dd7a46568ed234 204 Gene3D G3DSA:1.10.10.10 118 203 4.7E-27 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS12105 c1ed24ce2ad75f7c70dd7a46568ed234 204 SMART SM00421 140 197 4.0E-25 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS12105 c1ed24ce2ad75f7c70dd7a46568ed234 204 ProSitePatterns PS00622 LuxR-type HTH domain signature. 157 184 - T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS12105 c1ed24ce2ad75f7c70dd7a46568ed234 204 SUPERFAMILY SSF46894 137 202 1.63E-20 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS12105 c1ed24ce2ad75f7c70dd7a46568ed234 204 SUPERFAMILY SSF52172 1 124 9.82E-32 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS12105 c1ed24ce2ad75f7c70dd7a46568ed234 204 SMART SM00448 1 113 1.1E-33 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS12105 c1ed24ce2ad75f7c70dd7a46568ed234 204 Pfam PF00072 Response regulator receiver domain 3 114 2.4E-24 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS24180 213e113339be7575ea0450a23bd3cd3e 123 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 75 90 2.4E-17 T 10-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4G23_RS24180 213e113339be7575ea0450a23bd3cd3e 123 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 41 56 2.4E-17 T 10-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4G23_RS24180 213e113339be7575ea0450a23bd3cd3e 123 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 90 105 2.4E-17 T 10-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4G23_RS24180 213e113339be7575ea0450a23bd3cd3e 123 SMART SM00418 39 119 9.1E-31 T 10-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4G23_RS24180 213e113339be7575ea0450a23bd3cd3e 123 Gene3D G3DSA:1.10.10.10 20 117 5.9E-32 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS24180 213e113339be7575ea0450a23bd3cd3e 123 SUPERFAMILY SSF46785 22 117 1.32E-25 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS24180 213e113339be7575ea0450a23bd3cd3e 123 Pfam PF01022 Bacterial regulatory protein, arsR family 46 94 3.1E-15 T 10-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4G23_RS03575 15e4fd50afecf0e29b479335a7adfa69 166 Pfam PF01381 Helix-turn-helix 13 69 1.2E-8 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS03575 15e4fd50afecf0e29b479335a7adfa69 166 Gene3D G3DSA:1.10.260.40 3 75 4.7E-12 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS03575 15e4fd50afecf0e29b479335a7adfa69 166 SUPERFAMILY SSF47413 4 74 4.44E-9 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS03575 15e4fd50afecf0e29b479335a7adfa69 166 SMART SM00530 12 69 2.1E-6 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS12140 61d26958ee345de88b35591e9f4bc198 246 SUPERFAMILY SSF53448 6 235 1.19E-53 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS12140 61d26958ee345de88b35591e9f4bc198 246 Gene3D G3DSA:3.90.550.10 6 236 5.6E-55 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS12140 61d26958ee345de88b35591e9f4bc198 246 Pfam PF00483 Nucleotidyl transferase 8 234 3.3E-23 T 10-11-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A4G23_RS19095 545c3d66e250e0c08815de0414cdca97 313 Gene3D G3DSA:3.40.190.10 94 177 5.4E-13 T 10-11-2016 A4G23_RS19095 545c3d66e250e0c08815de0414cdca97 313 SUPERFAMILY SSF53850 91 287 4.16E-18 T 10-11-2016 A4G23_RS19095 545c3d66e250e0c08815de0414cdca97 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 2 59 1.5E-18 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS19095 545c3d66e250e0c08815de0414cdca97 313 Gene3D G3DSA:1.10.10.10 2 83 1.7E-21 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS19095 545c3d66e250e0c08815de0414cdca97 313 Gene3D G3DSA:3.40.190.10 178 262 1.6E-6 T 10-11-2016 A4G23_RS19095 545c3d66e250e0c08815de0414cdca97 313 SUPERFAMILY SSF46785 2 103 4.8E-20 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS19095 545c3d66e250e0c08815de0414cdca97 313 Pfam PF03466 LysR substrate binding domain 90 272 2.1E-20 T 10-11-2016 IPR005119 LysR, substrate-binding A4G23_RS19095 545c3d66e250e0c08815de0414cdca97 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 16 27 1.2E-7 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS19095 545c3d66e250e0c08815de0414cdca97 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 27 37 1.2E-7 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS19095 545c3d66e250e0c08815de0414cdca97 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 37 48 1.2E-7 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS23725 334e81543f607996ad2def41ba2e3d01 259 SUPERFAMILY SSF69754 20 115 1.09E-7 T 10-11-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 A4G23_RS23725 334e81543f607996ad2def41ba2e3d01 259 Gene3D G3DSA:3.30.160.100 20 101 1.7E-7 T 10-11-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 A4G23_RS23725 334e81543f607996ad2def41ba2e3d01 259 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 212 254 2.4E-8 T 10-11-2016 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal A4G23_RS23725 334e81543f607996ad2def41ba2e3d01 259 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 134 182 9.1E-12 T 10-11-2016 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal A4G23_RS23725 334e81543f607996ad2def41ba2e3d01 259 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 20 101 6.8E-5 T 10-11-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 A4G23_RS23395 a990c08325584f95eb28512370821d33 253 Gene3D G3DSA:1.25.40.10 56 234 1.8E-7 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS23395 a990c08325584f95eb28512370821d33 253 SUPERFAMILY SSF48452 91 200 4.74E-5 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS16015 37a8e1ae573e0a022fe47fcb22c3cb39 218 Pfam PF08241 Methyltransferase domain 52 147 4.7E-20 T 10-11-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 A4G23_RS16015 37a8e1ae573e0a022fe47fcb22c3cb39 218 SUPERFAMILY SSF53335 6 159 2.41E-38 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS16015 37a8e1ae573e0a022fe47fcb22c3cb39 218 Gene3D G3DSA:3.40.50.150 11 157 3.0E-34 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS25150 2fd384a10bf816d68a9040bce4420559 191 SUPERFAMILY SSF55781 35 186 2.62E-23 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS25150 2fd384a10bf816d68a9040bce4420559 191 SMART SM00065 33 189 9.2E-5 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS25150 2fd384a10bf816d68a9040bce4420559 191 Gene3D G3DSA:3.30.450.40 27 187 4.4E-17 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS25150 2fd384a10bf816d68a9040bce4420559 191 Pfam PF01590 GAF domain 35 178 2.9E-14 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS09150 843b6587adba8fe7810e50ab72e077f3 342 Pfam PF13377 Periplasmic binding protein-like domain 181 341 5.6E-39 T 10-11-2016 A4G23_RS09150 843b6587adba8fe7810e50ab72e077f3 342 Gene3D G3DSA:1.10.260.40 10 59 1.2E-21 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS09150 843b6587adba8fe7810e50ab72e077f3 342 ProSitePatterns PS00356 LacI-type HTH domain signature. 13 31 - T 10-11-2016 A4G23_RS09150 843b6587adba8fe7810e50ab72e077f3 342 SUPERFAMILY SSF47413 10 68 3.33E-16 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS09150 843b6587adba8fe7810e50ab72e077f3 342 Gene3D G3DSA:3.40.50.2300 60 187 1.2E-32 T 10-11-2016 A4G23_RS09150 843b6587adba8fe7810e50ab72e077f3 342 Gene3D G3DSA:3.40.50.2300 188 318 5.1E-50 T 10-11-2016 A4G23_RS09150 843b6587adba8fe7810e50ab72e077f3 342 SUPERFAMILY SSF53822 83 341 1.39E-71 T 10-11-2016 IPR028082 Periplasmic binding protein-like I A4G23_RS09150 843b6587adba8fe7810e50ab72e077f3 342 Pfam PF00356 Bacterial regulatory proteins, lacI family 12 57 2.5E-15 T 10-11-2016 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4G23_RS09150 843b6587adba8fe7810e50ab72e077f3 342 SMART SM00354 10 80 3.2E-26 T 10-11-2016 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4G23_RS04735 4c69376b2c2061695b6454b6790ee3c3 306 Gene3D G3DSA:3.40.50.1820 52 302 3.3E-80 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS04735 4c69376b2c2061695b6454b6790ee3c3 306 Pfam PF01674 Lipase (class 2) 71 248 4.0E-14 T 10-11-2016 IPR002918 Lipase EstA/Esterase EstB GO:0016787 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 A4G23_RS04735 4c69376b2c2061695b6454b6790ee3c3 306 SUPERFAMILY SSF53474 67 250 6.2E-29 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS23910 88cd04f3e366efa648c5592f57d798c3 206 Gene3D G3DSA:3.40.430.10 3 192 3.0E-29 T 10-11-2016 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 A4G23_RS23910 88cd04f3e366efa648c5592f57d798c3 206 SUPERFAMILY SSF53597 4 194 6.28E-30 T 10-11-2016 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 A4G23_RS23910 88cd04f3e366efa648c5592f57d798c3 206 Pfam PF01872 RibD C-terminal domain 4 186 8.0E-26 T 10-11-2016 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 A4G23_RS09885 3d7610853291fc8ad414fc3356fbae92 400 Pfam PF14258 Domain of unknown function (DUF4350) 52 122 4.0E-12 T 10-11-2016 IPR025646 Domain of unknown function DUF4350 A4G23_RS22040 c0d220441dac3411004893f9ccb74f6e 114 Gene3D G3DSA:1.10.10.10 9 91 6.6E-25 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS22040 c0d220441dac3411004893f9ccb74f6e 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 8.6E-9 T 10-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4G23_RS22040 c0d220441dac3411004893f9ccb74f6e 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 8.6E-9 T 10-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4G23_RS22040 c0d220441dac3411004893f9ccb74f6e 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 13 28 8.6E-9 T 10-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4G23_RS22040 c0d220441dac3411004893f9ccb74f6e 114 SUPERFAMILY SSF46785 3 88 2.81E-21 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS22040 c0d220441dac3411004893f9ccb74f6e 114 SMART SM00418 11 89 6.6E-26 T 10-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4G23_RS22040 c0d220441dac3411004893f9ccb74f6e 114 Pfam PF12840 Helix-turn-helix domain 11 68 2.7E-9 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS21245 c0d6b3391e5e79830ee695fe5b65c954 312 Gene3D G3DSA:3.40.50.300 7 176 2.6E-50 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS21245 c0d6b3391e5e79830ee695fe5b65c954 312 Pfam PF01715 IPP transferase 43 285 1.4E-72 T 10-11-2016 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 A4G23_RS21245 c0d6b3391e5e79830ee695fe5b65c954 312 SUPERFAMILY SSF52540 10 153 8.26E-17 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS21245 c0d6b3391e5e79830ee695fe5b65c954 312 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 10 311 27.535 T 10-11-2016 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 A4G23_RS21245 c0d6b3391e5e79830ee695fe5b65c954 312 Gene3D G3DSA:1.10.287.890 201 282 3.4E-26 T 10-11-2016 A4G23_RS21245 c0d6b3391e5e79830ee695fe5b65c954 312 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 10 289 1.1E-73 T 10-11-2016 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 A4G23_RS18050 a9bad96b5f34aa3f0045c0eb22cfa5b5 450 SUPERFAMILY SSF51419 47 260 1.47E-23 T 10-11-2016 IPR029066 PLP-binding barrel A4G23_RS18050 a9bad96b5f34aa3f0045c0eb22cfa5b5 450 SMART SM01119 304 437 6.2E-27 T 10-11-2016 IPR026956 D-serine dehydratase-like domain A4G23_RS18050 a9bad96b5f34aa3f0045c0eb22cfa5b5 450 Pfam PF01168 Alanine racemase, N-terminal domain 46 237 3.1E-11 T 10-11-2016 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4G23_RS18050 a9bad96b5f34aa3f0045c0eb22cfa5b5 450 Gene3D G3DSA:3.20.20.10 133 255 1.1E-12 T 10-11-2016 IPR029066 PLP-binding barrel A4G23_RS18050 a9bad96b5f34aa3f0045c0eb22cfa5b5 450 Pfam PF14031 Putative serine dehydratase domain 305 436 2.0E-12 T 10-11-2016 IPR026956 D-serine dehydratase-like domain A4G23_RS09660 1edeb3c47f0282f372f57e78ea100b10 446 SUPERFAMILY SSF55205 7 440 8.67E-111 T 10-11-2016 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 A4G23_RS09660 1edeb3c47f0282f372f57e78ea100b10 446 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 11 431 4.5E-57 T 10-11-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 A4G23_RS09660 1edeb3c47f0282f372f57e78ea100b10 446 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 7 439 2.0E-131 T 10-11-2016 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4G23_RS09660 1edeb3c47f0282f372f57e78ea100b10 446 Gene3D G3DSA:3.65.10.10 229 439 1.8E-47 T 10-11-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 A4G23_RS09660 1edeb3c47f0282f372f57e78ea100b10 446 Gene3D G3DSA:3.65.10.10 25 228 3.6E-52 T 10-11-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 A4G23_RS16915 2c404770db33b9dc8af89fabaf684dbb 305 Gene3D G3DSA:3.20.20.370 110 304 1.4E-38 T 10-11-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 A4G23_RS16915 2c404770db33b9dc8af89fabaf684dbb 305 SUPERFAMILY SSF88713 110 304 2.78E-39 T 10-11-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A4G23_RS16915 2c404770db33b9dc8af89fabaf684dbb 305 Pfam PF01522 Polysaccharide deacetylase 119 238 4.3E-26 T 10-11-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 A4G23_RS19335 cef9c5d633db9cd4c2c7961d2ea73773 227 SUPERFAMILY SSF52540 3 220 2.72E-64 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS19335 cef9c5d633db9cd4c2c7961d2ea73773 227 SMART SM00382 31 219 4.2E-14 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS19335 cef9c5d633db9cd4c2c7961d2ea73773 227 Pfam PF00005 ABC transporter 22 171 1.7E-35 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS19335 cef9c5d633db9cd4c2c7961d2ea73773 227 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS19335 cef9c5d633db9cd4c2c7961d2ea73773 227 Gene3D G3DSA:3.40.50.300 3 220 6.7E-67 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS10000 0651905d831c2fd803a371eed30462e7 319 SUPERFAMILY SSF48150 118 299 6.28E-26 T 10-11-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A4G23_RS10000 0651905d831c2fd803a371eed30462e7 319 Gene3D G3DSA:1.10.340.30 133 240 1.7E-17 T 10-11-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A4G23_RS00835 3a23716572f98c425ba69b2f6ab91abf 249 SMART SM00895 87 211 4.1E-14 T 10-11-2016 IPR011711 GntR, C-terminal A4G23_RS00835 3a23716572f98c425ba69b2f6ab91abf 249 SMART SM00345 19 77 2.3E-12 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS00835 3a23716572f98c425ba69b2f6ab91abf 249 Gene3D G3DSA:1.20.120.530 80 214 9.8E-26 T 10-11-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal A4G23_RS00835 3a23716572f98c425ba69b2f6ab91abf 249 Pfam PF07729 FCD domain 87 210 9.2E-22 T 10-11-2016 IPR011711 GntR, C-terminal A4G23_RS00835 3a23716572f98c425ba69b2f6ab91abf 249 SUPERFAMILY SSF48008 84 216 8.37E-25 T 10-11-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal A4G23_RS00835 3a23716572f98c425ba69b2f6ab91abf 249 Gene3D G3DSA:1.10.10.10 15 79 1.0E-20 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS00835 3a23716572f98c425ba69b2f6ab91abf 249 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 77 9.4E-16 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS00835 3a23716572f98c425ba69b2f6ab91abf 249 SUPERFAMILY SSF46785 14 81 1.93E-16 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS18890 bdae162b4a7f3ae9cf8a43b60161c4aa 483 Gene3D G3DSA:2.40.180.10 4 357 9.5E-182 T 10-11-2016 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 A4G23_RS18890 bdae162b4a7f3ae9cf8a43b60161c4aa 483 Pfam PF00199 Catalase 7 388 1.3E-188 T 10-11-2016 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 A4G23_RS18890 bdae162b4a7f3ae9cf8a43b60161c4aa 483 PRINTS PR00067 Catalase signature 20 43 1.9E-69 T 10-11-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 A4G23_RS18890 bdae162b4a7f3ae9cf8a43b60161c4aa 483 PRINTS PR00067 Catalase signature 123 141 1.9E-69 T 10-11-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 A4G23_RS18890 bdae162b4a7f3ae9cf8a43b60161c4aa 483 PRINTS PR00067 Catalase signature 288 315 1.9E-69 T 10-11-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 A4G23_RS18890 bdae162b4a7f3ae9cf8a43b60161c4aa 483 PRINTS PR00067 Catalase signature 83 101 1.9E-69 T 10-11-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 A4G23_RS18890 bdae162b4a7f3ae9cf8a43b60161c4aa 483 PRINTS PR00067 Catalase signature 104 121 1.9E-69 T 10-11-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 A4G23_RS18890 bdae162b4a7f3ae9cf8a43b60161c4aa 483 PRINTS PR00067 Catalase signature 320 346 1.9E-69 T 10-11-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 A4G23_RS18890 bdae162b4a7f3ae9cf8a43b60161c4aa 483 Pfam PF06628 Catalase-related immune-responsive 418 478 2.0E-20 T 10-11-2016 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 A4G23_RS18890 bdae162b4a7f3ae9cf8a43b60161c4aa 483 SUPERFAMILY SSF56634 5 479 6.15E-207 T 10-11-2016 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 A4G23_RS18890 bdae162b4a7f3ae9cf8a43b60161c4aa 483 PIRSF PIRSF038928 1 482 1.5E-219 T 10-11-2016 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 A4G23_RS18890 bdae162b4a7f3ae9cf8a43b60161c4aa 483 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 333 341 - T 10-11-2016 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 A4G23_RS18890 bdae162b4a7f3ae9cf8a43b60161c4aa 483 SMART SM01060 7 391 6.3E-283 T 10-11-2016 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 A4G23_RS18890 bdae162b4a7f3ae9cf8a43b60161c4aa 483 ProSitePatterns PS00438 Catalase proximal active site signature. 43 59 - T 10-11-2016 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 A4G23_RS06690 0645334d3b4386db2c7236039da359ae 462 SUPERFAMILY SSF55424 338 459 7.73E-29 T 10-11-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 A4G23_RS06690 0645334d3b4386db2c7236039da359ae 462 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 43 53 - T 10-11-2016 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 A4G23_RS06690 0645334d3b4386db2c7236039da359ae 462 Gene3D G3DSA:3.30.390.30 341 459 1.4E-27 T 10-11-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A4G23_RS06690 0645334d3b4386db2c7236039da359ae 462 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 341 449 2.8E-23 T 10-11-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A4G23_RS06690 0645334d3b4386db2c7236039da359ae 462 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 9 459 1.6E-137 T 10-11-2016 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 A4G23_RS06690 0645334d3b4386db2c7236039da359ae 462 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 9 321 1.2E-66 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS06690 0645334d3b4386db2c7236039da359ae 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 5.6E-64 T 10-11-2016 A4G23_RS06690 0645334d3b4386db2c7236039da359ae 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 174 199 5.6E-64 T 10-11-2016 A4G23_RS06690 0645334d3b4386db2c7236039da359ae 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 301 308 5.6E-64 T 10-11-2016 A4G23_RS06690 0645334d3b4386db2c7236039da359ae 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 259 273 5.6E-64 T 10-11-2016 A4G23_RS06690 0645334d3b4386db2c7236039da359ae 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 424 444 5.6E-64 T 10-11-2016 A4G23_RS06690 0645334d3b4386db2c7236039da359ae 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 138 147 5.6E-64 T 10-11-2016 A4G23_RS06690 0645334d3b4386db2c7236039da359ae 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 42 57 5.6E-64 T 10-11-2016 A4G23_RS06690 0645334d3b4386db2c7236039da359ae 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 337 358 5.6E-64 T 10-11-2016 A4G23_RS06690 0645334d3b4386db2c7236039da359ae 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 402 417 5.6E-64 T 10-11-2016 A4G23_RS06690 0645334d3b4386db2c7236039da359ae 462 Gene3D G3DSA:3.50.50.60 141 330 4.7E-47 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS06690 0645334d3b4386db2c7236039da359ae 462 PIRSF PIRSF000350 1 444 1.2E-69 T 10-11-2016 A4G23_RS06690 0645334d3b4386db2c7236039da359ae 462 Gene3D G3DSA:3.50.50.60 9 140 5.4E-39 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS06690 0645334d3b4386db2c7236039da359ae 462 SUPERFAMILY SSF51905 7 366 5.79E-59 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS06690 0645334d3b4386db2c7236039da359ae 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 286 308 2.8E-34 T 10-11-2016 A4G23_RS06690 0645334d3b4386db2c7236039da359ae 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 135 153 2.8E-34 T 10-11-2016 A4G23_RS06690 0645334d3b4386db2c7236039da359ae 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 174 192 2.8E-34 T 10-11-2016 A4G23_RS06690 0645334d3b4386db2c7236039da359ae 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 2.8E-34 T 10-11-2016 A4G23_RS06690 0645334d3b4386db2c7236039da359ae 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 274 2.8E-34 T 10-11-2016 A4G23_RS26060 a1abe7f4da6eb0df7477508da4059cf6 275 Pfam PF00805 Pentapeptide repeats (8 copies) 209 245 5.6E-12 T 10-11-2016 IPR001646 Pentapeptide repeat A4G23_RS26060 a1abe7f4da6eb0df7477508da4059cf6 275 SUPERFAMILY SSF141571 57 93 2.75E-23 T 10-11-2016 A4G23_RS26060 a1abe7f4da6eb0df7477508da4059cf6 275 SUPERFAMILY SSF141571 167 268 2.75E-23 T 10-11-2016 A4G23_RS05410 248742276a86dc76be627fa42330040f 216 SMART SM00421 150 207 3.9E-21 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS05410 248742276a86dc76be627fa42330040f 216 Gene3D G3DSA:3.40.50.2300 1 152 1.3E-37 T 10-11-2016 A4G23_RS05410 248742276a86dc76be627fa42330040f 216 SUPERFAMILY SSF46894 142 213 1.16E-20 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS05410 248742276a86dc76be627fa42330040f 216 Pfam PF00072 Response regulator receiver domain 3 116 9.8E-28 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS05410 248742276a86dc76be627fa42330040f 216 Gene3D G3DSA:1.10.10.10 153 211 1.1E-26 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS05410 248742276a86dc76be627fa42330040f 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 1.9E-12 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS05410 248742276a86dc76be627fa42330040f 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 1.9E-12 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS05410 248742276a86dc76be627fa42330040f 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 1.9E-12 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS05410 248742276a86dc76be627fa42330040f 216 ProSitePatterns PS00622 LuxR-type HTH domain signature. 167 194 - T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS05410 248742276a86dc76be627fa42330040f 216 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 206 9.9E-17 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS05410 248742276a86dc76be627fa42330040f 216 SMART SM00448 1 115 5.4E-29 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS05410 248742276a86dc76be627fa42330040f 216 SUPERFAMILY SSF52172 1 122 2.85E-31 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS02350 fbfe0bf8395e5cca2449b7ca4b08e81c 369 PIRSF PIRSF000390 5 369 1.7E-110 T 10-11-2016 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A4G23_RS02350 fbfe0bf8395e5cca2449b7ca4b08e81c 369 Gene3D G3DSA:3.90.1150.10 246 367 7.1E-40 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS02350 fbfe0bf8395e5cca2449b7ca4b08e81c 369 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 17 363 2.7E-126 T 10-11-2016 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A4G23_RS02350 fbfe0bf8395e5cca2449b7ca4b08e81c 369 SUPERFAMILY SSF53383 17 366 2.18E-109 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS02350 fbfe0bf8395e5cca2449b7ca4b08e81c 369 Gene3D G3DSA:3.40.640.10 18 243 1.7E-77 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS10615 5027c64a80a859d0c932da4e2cb5a485 349 SUPERFAMILY SSF54197 38 179 1.04E-45 T 10-11-2016 IPR011146 HIT-like domain GO:0003824 A4G23_RS10615 5027c64a80a859d0c932da4e2cb5a485 349 Gene3D G3DSA:3.30.428.10 64 177 1.5E-33 T 10-11-2016 IPR011146 HIT-like domain GO:0003824 A4G23_RS10615 5027c64a80a859d0c932da4e2cb5a485 349 TIGRFAM TIGR00209 galT_1: galactose-1-phosphate uridylyltransferase 103 346 1.9E-38 T 10-11-2016 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0006012|GO:0008108|GO:0008270 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 A4G23_RS10615 5027c64a80a859d0c932da4e2cb5a485 349 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 192 343 6.8E-16 T 10-11-2016 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 A4G23_RS10615 5027c64a80a859d0c932da4e2cb5a485 349 SUPERFAMILY SSF54197 182 346 1.19E-33 T 10-11-2016 IPR011146 HIT-like domain GO:0003824 A4G23_RS10615 5027c64a80a859d0c932da4e2cb5a485 349 Gene3D G3DSA:3.30.428.10 180 346 1.1E-49 T 10-11-2016 IPR011146 HIT-like domain GO:0003824 A4G23_RS10615 5027c64a80a859d0c932da4e2cb5a485 349 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 103 178 2.3E-26 T 10-11-2016 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 A4G23_RS10615 5027c64a80a859d0c932da4e2cb5a485 349 ProSitePatterns PS00117 Galactose-1-phosphate uridyl transferase family 1 active site signature. 154 171 - T 10-11-2016 IPR019779 Galactose-1-phosphate uridyl transferase, class I His-active site GO:0006012|GO:0008108|GO:0008270 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 A4G23_RS10615 5027c64a80a859d0c932da4e2cb5a485 349 PIRSF PIRSF000808 34 348 4.4E-101 T 10-11-2016 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0006012|GO:0008108|GO:0008270 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 A4G23_RS00595 1ee88735b601af29a16e14b368d27407 137 Pfam PF01479 S4 domain 19 64 4.3E-13 T 10-11-2016 IPR002942 RNA-binding S4 domain GO:0003723 A4G23_RS00595 1ee88735b601af29a16e14b368d27407 137 SMART SM00363 18 82 3.9E-7 T 10-11-2016 IPR002942 RNA-binding S4 domain GO:0003723 A4G23_RS00595 1ee88735b601af29a16e14b368d27407 137 Gene3D G3DSA:3.10.290.10 18 108 1.1E-29 T 10-11-2016 IPR002942 RNA-binding S4 domain GO:0003723 A4G23_RS00595 1ee88735b601af29a16e14b368d27407 137 SUPERFAMILY SSF55174 17 100 1.7E-23 T 10-11-2016 A4G23_RS00595 1ee88735b601af29a16e14b368d27407 137 PIRSF PIRSF016821 15 136 6.7E-45 T 10-11-2016 IPR025708 Heat shock protein 15 GO:0003677|GO:0003727|GO:0034605|GO:0043023 A4G23_RS21095 713de0ecd180bed899f8af748df53624 171 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 8 155 7.5E-34 T 10-11-2016 IPR008136 CinA, C-terminal A4G23_RS21095 713de0ecd180bed899f8af748df53624 171 Pfam PF02464 Competence-damaged protein 2 155 1.3E-48 T 10-11-2016 IPR008136 CinA, C-terminal A4G23_RS21095 713de0ecd180bed899f8af748df53624 171 SUPERFAMILY SSF142433 2 156 3.92E-46 T 10-11-2016 IPR008136 CinA, C-terminal A4G23_RS21095 713de0ecd180bed899f8af748df53624 171 Gene3D G3DSA:3.90.950.20 2 156 9.3E-57 T 10-11-2016 IPR008136 CinA, C-terminal A4G23_RS24470 99845f23ade9a1fb87dcd7b640a60f6f 255 Pfam PF12706 Beta-lactamase superfamily domain 19 204 8.9E-30 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS24470 99845f23ade9a1fb87dcd7b640a60f6f 255 Gene3D G3DSA:3.60.15.10 1 250 7.5E-51 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS24470 99845f23ade9a1fb87dcd7b640a60f6f 255 SUPERFAMILY SSF56281 1 208 3.5E-26 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS01945 47febdd1553a485d8c0fcfca438f0eb9 179 SMART SM00903 27 176 3.7E-50 T 10-11-2016 IPR002563 Flavin reductase like domain GO:0010181 A4G23_RS01945 47febdd1553a485d8c0fcfca438f0eb9 179 Pfam PF01613 Flavin reductase like domain 27 177 3.2E-41 T 10-11-2016 IPR002563 Flavin reductase like domain GO:0010181 A4G23_RS01945 47febdd1553a485d8c0fcfca438f0eb9 179 Gene3D G3DSA:2.30.110.10 20 175 2.2E-53 T 10-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 A4G23_RS01945 47febdd1553a485d8c0fcfca438f0eb9 179 SUPERFAMILY SSF50475 20 175 2.6E-44 T 10-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 A4G23_RS07830 20afd16d2ff6534b6b1d93a3a712b104 251 Hamap MF_00201 DNA repair protein RecO [recO]. 2 249 26.653 T 10-11-2016 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 A4G23_RS07830 20afd16d2ff6534b6b1d93a3a712b104 251 Pfam PF11967 Recombination protein O N terminal 1 85 8.9E-28 T 10-11-2016 IPR022572 DNA replication/recombination mediator RecO, N-terminal A4G23_RS07830 20afd16d2ff6534b6b1d93a3a712b104 251 Gene3D G3DSA:2.40.50.140 1 86 1.3E-34 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS07830 20afd16d2ff6534b6b1d93a3a712b104 251 SUPERFAMILY SSF50249 1 85 2.23E-18 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS07830 20afd16d2ff6534b6b1d93a3a712b104 251 SUPERFAMILY SSF57863 89 238 3.4E-39 T 10-11-2016 A4G23_RS07830 20afd16d2ff6534b6b1d93a3a712b104 251 Pfam PF02565 Recombination protein O C terminal 91 244 1.2E-33 T 10-11-2016 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 A4G23_RS07830 20afd16d2ff6534b6b1d93a3a712b104 251 TIGRFAM TIGR00613 reco: DNA repair protein RecO 5 242 7.8E-35 T 10-11-2016 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 A4G23_RS02530 22491d90783fe2d4c7858d9e897bb622 907 SUPERFAMILY SSF55874 48 157 2.61E-6 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS02530 22491d90783fe2d4c7858d9e897bb622 907 SMART SM00331 686 903 6.5E-26 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS02530 22491d90783fe2d4c7858d9e897bb622 907 SUPERFAMILY SSF55785 318 413 7.26E-15 T 10-11-2016 IPR000014 PAS domain A4G23_RS02530 22491d90783fe2d4c7858d9e897bb622 907 Pfam PF01590 GAF domain 537 657 8.0E-12 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS02530 22491d90783fe2d4c7858d9e897bb622 907 SUPERFAMILY SSF55781 510 671 3.49E-18 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS02530 22491d90783fe2d4c7858d9e897bb622 907 SMART SM00065 510 669 4.2E-9 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS02530 22491d90783fe2d4c7858d9e897bb622 907 Gene3D G3DSA:3.30.450.40 499 667 3.4E-28 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS02530 22491d90783fe2d4c7858d9e897bb622 907 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 311 414 2.3E-12 T 10-11-2016 IPR000014 PAS domain A4G23_RS02530 22491d90783fe2d4c7858d9e897bb622 907 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 716 902 1.1E-39 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS02530 22491d90783fe2d4c7858d9e897bb622 907 Pfam PF00989 PAS fold 311 408 1.3E-6 T 10-11-2016 IPR013767 PAS fold GO:0006355 A4G23_RS02530 22491d90783fe2d4c7858d9e897bb622 907 SMART SM00091 304 370 4.7E-5 T 10-11-2016 IPR000014 PAS domain A4G23_RS02530 22491d90783fe2d4c7858d9e897bb622 907 Gene3D G3DSA:3.30.450.20 311 413 4.3E-13 T 10-11-2016 A4G23_RS02930 fa34deaf0408d1b57d568ed22024ffd9 302 SUPERFAMILY SSF51735 1 137 9.85E-35 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS02930 fa34deaf0408d1b57d568ed22024ffd9 302 SUPERFAMILY SSF55347 123 258 1.48E-34 T 10-11-2016 A4G23_RS02930 fa34deaf0408d1b57d568ed22024ffd9 302 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 2 121 6.3E-15 T 10-11-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 A4G23_RS02930 fa34deaf0408d1b57d568ed22024ffd9 302 Gene3D G3DSA:3.30.360.10 128 299 1.4E-56 T 10-11-2016 A4G23_RS02930 fa34deaf0408d1b57d568ed22024ffd9 302 Gene3D G3DSA:3.40.50.720 1 127 3.5E-31 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS18700 ff564d36b30067106463e2d9e5341218 320 Gene3D G3DSA:3.90.25.10 189 313 1.3E-14 T 10-11-2016 A4G23_RS18700 ff564d36b30067106463e2d9e5341218 320 Gene3D G3DSA:3.40.50.720 1 188 3.9E-26 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS18700 ff564d36b30067106463e2d9e5341218 320 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 222 1.8E-32 T 10-11-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 A4G23_RS18700 ff564d36b30067106463e2d9e5341218 320 SUPERFAMILY SSF51735 284 313 4.76E-51 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS18700 ff564d36b30067106463e2d9e5341218 320 SUPERFAMILY SSF51735 1 256 4.76E-51 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS10125 60574d2ebe506351d1531cc6f2280759 499 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 159 171 - T 10-11-2016 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 A4G23_RS10125 60574d2ebe506351d1531cc6f2280759 499 SUPERFAMILY SSF103473 17 216 4.58E-29 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS10125 60574d2ebe506351d1531cc6f2280759 499 SUPERFAMILY SSF103473 276 492 4.58E-29 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS10125 60574d2ebe506351d1531cc6f2280759 499 Gene3D G3DSA:1.20.1250.20 28 212 2.1E-13 T 10-11-2016 A4G23_RS10125 60574d2ebe506351d1531cc6f2280759 499 Gene3D G3DSA:1.20.1250.20 294 490 5.1E-5 T 10-11-2016 A4G23_RS10125 60574d2ebe506351d1531cc6f2280759 499 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 16 495 4.3E-166 T 10-11-2016 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 A4G23_RS10125 60574d2ebe506351d1531cc6f2280759 499 Pfam PF00854 POT family 97 455 1.8E-60 T 10-11-2016 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 A4G23_RS13315 a83a339914dd4838878898ca9dea13da 490 Pfam PF10009 Uncharacterized protein conserved in bacteria (DUF2252) 87 477 2.6E-136 T 10-11-2016 IPR018721 Protein of unknown function DUF2252 A4G23_RS25085 e7e5432c3efa0aacafdaabf8ee9d8847 409 Gene3D G3DSA:3.50.50.60 241 311 2.0E-11 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS25085 e7e5432c3efa0aacafdaabf8ee9d8847 409 Gene3D G3DSA:3.50.50.60 13 166 2.0E-11 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS25085 e7e5432c3efa0aacafdaabf8ee9d8847 409 Pfam PF05834 Lycopene cyclase protein 14 387 2.0E-115 T 10-11-2016 A4G23_RS25085 e7e5432c3efa0aacafdaabf8ee9d8847 409 SUPERFAMILY SSF51905 264 326 1.84E-17 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS25085 e7e5432c3efa0aacafdaabf8ee9d8847 409 SUPERFAMILY SSF51905 12 178 1.84E-17 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS04360 6f7553c79b4699bd414580fe3949355c 233 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 92 199 1.5E-14 T 10-11-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A4G23_RS04360 6f7553c79b4699bd414580fe3949355c 233 Pfam PF13419 Haloacid dehalogenase-like hydrolase 23 199 3.2E-25 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS04360 6f7553c79b4699bd414580fe3949355c 233 SUPERFAMILY SSF56784 19 215 2.98E-46 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS04360 6f7553c79b4699bd414580fe3949355c 233 Gene3D G3DSA:3.40.50.1000 104 220 2.6E-41 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS04360 6f7553c79b4699bd414580fe3949355c 233 Gene3D G3DSA:3.40.50.1000 11 32 2.6E-41 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS04360 6f7553c79b4699bd414580fe3949355c 233 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 143 159 2.2E-5 T 10-11-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A4G23_RS04360 6f7553c79b4699bd414580fe3949355c 233 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 18 29 2.2E-5 T 10-11-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A4G23_RS04360 6f7553c79b4699bd414580fe3949355c 233 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 113 126 2.2E-5 T 10-11-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A4G23_RS04360 6f7553c79b4699bd414580fe3949355c 233 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 161 181 2.2E-5 T 10-11-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A4G23_RS20670 0d854616290f28eb2ba4255df7d400a1 230 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 9 220 3.3E-30 T 10-11-2016 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 A4G23_RS20670 0d854616290f28eb2ba4255df7d400a1 230 Gene3D G3DSA:3.20.20.190 3 226 1.9E-46 T 10-11-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 A4G23_RS20670 0d854616290f28eb2ba4255df7d400a1 230 SUPERFAMILY SSF51695 4 224 5.76E-48 T 10-11-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 A4G23_RS21505 d59a1d9ca2194c7f257469883cfdd141 412 SMART SM00388 193 259 4.1E-13 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS21505 d59a1d9ca2194c7f257469883cfdd141 412 SMART SM00387 301 412 6.7E-25 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS21505 d59a1d9ca2194c7f257469883cfdd141 412 PRINTS PR00344 Bacterial sensor protein C-terminal signature 374 392 3.2E-10 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS21505 d59a1d9ca2194c7f257469883cfdd141 412 PRINTS PR00344 Bacterial sensor protein C-terminal signature 357 367 3.2E-10 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS21505 d59a1d9ca2194c7f257469883cfdd141 412 PRINTS PR00344 Bacterial sensor protein C-terminal signature 339 353 3.2E-10 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS21505 d59a1d9ca2194c7f257469883cfdd141 412 PRINTS PR00344 Bacterial sensor protein C-terminal signature 398 411 3.2E-10 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS21505 d59a1d9ca2194c7f257469883cfdd141 412 Pfam PF00672 HAMP domain 120 189 5.8E-14 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS21505 d59a1d9ca2194c7f257469883cfdd141 412 SUPERFAMILY SSF55874 250 412 9.17E-34 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS21505 d59a1d9ca2194c7f257469883cfdd141 412 Gene3D G3DSA:1.10.287.130 183 255 7.0E-11 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS21505 d59a1d9ca2194c7f257469883cfdd141 412 Gene3D G3DSA:3.30.565.10 261 411 2.3E-36 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS21505 d59a1d9ca2194c7f257469883cfdd141 412 SUPERFAMILY SSF47384 176 258 6.08E-15 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS21505 d59a1d9ca2194c7f257469883cfdd141 412 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 305 411 3.6E-16 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS21505 d59a1d9ca2194c7f257469883cfdd141 412 SUPERFAMILY SSF158472 140 189 1.83E-9 T 10-11-2016 A4G23_RS21505 d59a1d9ca2194c7f257469883cfdd141 412 SMART SM00304 139 192 3.3E-12 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS21505 d59a1d9ca2194c7f257469883cfdd141 412 Pfam PF00512 His Kinase A (phospho-acceptor) domain 194 258 2.8E-10 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS09935 1d92c48a216a0e8d0a0f199aec8e3672 305 Gene3D G3DSA:1.20.1510.10 8 218 2.0E-33 T 10-11-2016 IPR027469 Cation efflux protein transmembrane domain A4G23_RS09935 1d92c48a216a0e8d0a0f199aec8e3672 305 SUPERFAMILY SSF160240 225 295 3.92E-7 T 10-11-2016 A4G23_RS09935 1d92c48a216a0e8d0a0f199aec8e3672 305 Gene3D G3DSA:3.30.70.1350 223 298 5.7E-6 T 10-11-2016 IPR027470 Cation efflux protein, cytoplasmic domain A4G23_RS09935 1d92c48a216a0e8d0a0f199aec8e3672 305 SUPERFAMILY SSF161111 6 219 1.44E-38 T 10-11-2016 A4G23_RS09935 1d92c48a216a0e8d0a0f199aec8e3672 305 Pfam PF01545 Cation efflux family 11 218 9.8E-34 T 10-11-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A4G23_RS09935 1d92c48a216a0e8d0a0f199aec8e3672 305 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 8 288 1.6E-39 T 10-11-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A4G23_RS04820 81d6054adea1aa081498f04a5ed6c35a 231 Pfam PF00005 ABC transporter 20 154 4.6E-21 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS04820 81d6054adea1aa081498f04a5ed6c35a 231 Gene3D G3DSA:3.40.50.300 5 213 1.7E-40 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS04820 81d6054adea1aa081498f04a5ed6c35a 231 SMART SM00382 29 203 4.7E-4 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS04820 81d6054adea1aa081498f04a5ed6c35a 231 ProSitePatterns PS00211 ABC transporters family signature. 127 141 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS04820 81d6054adea1aa081498f04a5ed6c35a 231 SUPERFAMILY SSF52540 5 213 1.15E-43 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS26000 41ff8c8b7e1868ddedda813b58221871 165 SUPERFAMILY SSF55811 19 147 1.62E-23 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS26000 41ff8c8b7e1868ddedda813b58221871 165 Gene3D G3DSA:3.90.79.10 20 145 8.5E-21 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS26000 41ff8c8b7e1868ddedda813b58221871 165 Pfam PF00293 NUDIX domain 15 131 6.3E-16 T 10-11-2016 IPR000086 NUDIX hydrolase domain GO:0016787 A4G23_RS20835 402f127faad6459139a807b92898d94c 419 Gene3D G3DSA:3.40.50.720 20 171 4.3E-52 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS20835 402f127faad6459139a807b92898d94c 419 PIRSF PIRSF006205 21 413 1.1E-139 T 10-11-2016 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 A4G23_RS20835 402f127faad6459139a807b92898d94c 419 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 24 406 43.909 T 10-11-2016 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 A4G23_RS20835 402f127faad6459139a807b92898d94c 419 Pfam PF13288 DXP reductoisomerase C-terminal domain 284 401 7.1E-31 T 10-11-2016 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 A4G23_RS20835 402f127faad6459139a807b92898d94c 419 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 24 155 1.1E-39 T 10-11-2016 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 A4G23_RS20835 402f127faad6459139a807b92898d94c 419 SUPERFAMILY SSF51735 22 171 1.02E-36 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS20835 402f127faad6459139a807b92898d94c 419 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 23 406 8.8E-111 T 10-11-2016 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 A4G23_RS20835 402f127faad6459139a807b92898d94c 419 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 167 250 7.5E-36 T 10-11-2016 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 A4G23_RS20835 402f127faad6459139a807b92898d94c 419 Gene3D G3DSA:1.10.1740.10 324 407 6.3E-30 T 10-11-2016 A4G23_RS20835 402f127faad6459139a807b92898d94c 419 SUPERFAMILY SSF55347 149 285 8.5E-53 T 10-11-2016 A4G23_RS20835 402f127faad6459139a807b92898d94c 419 SUPERFAMILY SSF69055 314 407 1.06E-25 T 10-11-2016 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 A4G23_RS00395 6670e576cd0e10fe6298d2fc57474cab 116 SUPERFAMILY SSF46785 17 108 5.16E-14 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS00395 6670e576cd0e10fe6298d2fc57474cab 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 64 79 2.7E-6 T 10-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4G23_RS00395 6670e576cd0e10fe6298d2fc57474cab 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 32 47 2.7E-6 T 10-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4G23_RS00395 6670e576cd0e10fe6298d2fc57474cab 116 Pfam PF12840 Helix-turn-helix domain 31 83 1.5E-7 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS00395 6670e576cd0e10fe6298d2fc57474cab 116 SMART SM00418 30 108 6.4E-9 T 10-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4G23_RS00395 6670e576cd0e10fe6298d2fc57474cab 116 Gene3D G3DSA:1.10.10.10 26 108 6.3E-15 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS08340 f8d00ce39b775f95bec2beb05a68f32d 149 SUPERFAMILY SSF109604 6 140 1.49E-24 T 10-11-2016 A4G23_RS08340 f8d00ce39b775f95bec2beb05a68f32d 149 Pfam PF13328 HD domain 12 86 9.9E-11 T 10-11-2016 IPR003607 HD/PDEase domain A4G23_RS07180 a61ed1073a5d2d3e1c90be4228c9023e 452 SUPERFAMILY SSF48239 288 354 2.3E-22 T 10-11-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A4G23_RS07180 a61ed1073a5d2d3e1c90be4228c9023e 452 SUPERFAMILY SSF48239 77 207 2.3E-22 T 10-11-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A4G23_RS07180 a61ed1073a5d2d3e1c90be4228c9023e 452 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 104 148 0.063 T 10-11-2016 IPR001330 PFTB repeat GO:0003824 A4G23_RS07180 a61ed1073a5d2d3e1c90be4228c9023e 452 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 162 203 1.8E-7 T 10-11-2016 IPR001330 PFTB repeat GO:0003824 A4G23_RS07180 a61ed1073a5d2d3e1c90be4228c9023e 452 Gene3D G3DSA:1.50.10.20 76 206 1.1E-18 T 10-11-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A4G23_RS08710 6b2f9098c7a17efcac41fb0afba7cd57 182 Gene3D G3DSA:1.20.1260.10 55 106 1.0E-4 T 10-11-2016 IPR012347 Ferritin-related A4G23_RS08710 6b2f9098c7a17efcac41fb0afba7cd57 182 Pfam PF13628 Domain of unknown function (DUF4142) 2 118 8.1E-22 T 10-11-2016 IPR025419 Domain of unknown function DUF4142 A4G23_RS07825 8ef9b90c6ded5dd7904d785edb1529fb 302 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 36 264 39.203 T 10-11-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A4G23_RS07825 8ef9b90c6ded5dd7904d785edb1529fb 302 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 36 263 4.3E-79 T 10-11-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A4G23_RS07825 8ef9b90c6ded5dd7904d785edb1529fb 302 SUPERFAMILY SSF64005 36 259 1.31E-85 T 10-11-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A4G23_RS07825 8ef9b90c6ded5dd7904d785edb1529fb 302 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 209 226 - T 10-11-2016 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 A4G23_RS07825 8ef9b90c6ded5dd7904d785edb1529fb 302 Gene3D G3DSA:3.40.1180.10 34 264 2.7E-94 T 10-11-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A4G23_RS07825 8ef9b90c6ded5dd7904d785edb1529fb 302 Pfam PF01255 Putative undecaprenyl diphosphate synthase 43 263 5.9E-76 T 10-11-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A4G23_RS00955 1a281dc5d5c72bcd929e48e80e1b81c0 259 SUPERFAMILY SSF46785 23 92 2.01E-19 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS00955 1a281dc5d5c72bcd929e48e80e1b81c0 259 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 63 5.5E-10 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS00955 1a281dc5d5c72bcd929e48e80e1b81c0 259 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 63 79 5.5E-10 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS00955 1a281dc5d5c72bcd929e48e80e1b81c0 259 SMART SM00345 30 88 1.8E-12 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS00955 1a281dc5d5c72bcd929e48e80e1b81c0 259 Gene3D G3DSA:1.10.10.10 23 92 9.9E-22 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS00955 1a281dc5d5c72bcd929e48e80e1b81c0 259 Pfam PF00392 Bacterial regulatory proteins, gntR family 26 85 5.1E-18 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS26540 f99743c0e134e68be7330ebb5e834e2e 631 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 410 535 1.1E-25 T 10-11-2016 IPR003959 ATPase, AAA-type, core GO:0005524 A4G23_RS26540 f99743c0e134e68be7330ebb5e834e2e 631 Gene3D G3DSA:3.40.50.300 362 549 7.8E-35 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS26540 f99743c0e134e68be7330ebb5e834e2e 631 Gene3D G3DSA:1.10.8.60 552 601 4.5E-4 T 10-11-2016 A4G23_RS26540 f99743c0e134e68be7330ebb5e834e2e 631 SUPERFAMILY SSF52540 361 600 2.03E-40 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS26540 f99743c0e134e68be7330ebb5e834e2e 631 SMART SM00382 405 537 6.4E-12 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS10105 1625cf87815ebb56fdfd25998a53340b 380 SUPERFAMILY SSF56059 102 301 3.36E-57 T 10-11-2016 A4G23_RS10105 1625cf87815ebb56fdfd25998a53340b 380 Gene3D G3DSA:3.30.1490.20 113 157 2.3E-11 T 10-11-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A4G23_RS10105 1625cf87815ebb56fdfd25998a53340b 380 Gene3D G3DSA:3.30.470.20 158 376 3.2E-81 T 10-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 A4G23_RS10105 1625cf87815ebb56fdfd25998a53340b 380 Pfam PF02222 ATP-grasp domain 111 281 4.4E-48 T 10-11-2016 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type A4G23_RS10105 1625cf87815ebb56fdfd25998a53340b 380 SUPERFAMILY SSF52440 4 97 8.34E-26 T 10-11-2016 IPR016185 Pre-ATP-grasp domain A4G23_RS10105 1625cf87815ebb56fdfd25998a53340b 380 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 5 360 39.286 T 10-11-2016 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 A4G23_RS10105 1625cf87815ebb56fdfd25998a53340b 380 Gene3D G3DSA:3.40.50.20 4 108 5.8E-29 T 10-11-2016 IPR016185 Pre-ATP-grasp domain A4G23_RS10105 1625cf87815ebb56fdfd25998a53340b 380 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 6 364 7.8E-115 T 10-11-2016 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 A4G23_RS10105 1625cf87815ebb56fdfd25998a53340b 380 SUPERFAMILY SSF51246 307 376 3.3E-17 T 10-11-2016 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4G23_RS16530 86345eeafb61cd54558e5d9c731faa46 592 SUPERFAMILY SSF52540 441 571 1.77E-15 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS16530 86345eeafb61cd54558e5d9c731faa46 592 SUPERFAMILY SSF56091 3 206 4.68E-37 T 10-11-2016 A4G23_RS16530 86345eeafb61cd54558e5d9c731faa46 592 Pfam PF13671 AAA domain 443 571 4.7E-18 T 10-11-2016 A4G23_RS16530 86345eeafb61cd54558e5d9c731faa46 592 Pfam PF09414 RNA ligase 33 183 3.8E-23 T 10-11-2016 IPR021122 RNA ligase domain, REL/Rln2 A4G23_RS16530 86345eeafb61cd54558e5d9c731faa46 592 Gene3D G3DSA:3.40.50.300 442 571 1.1E-18 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS08170 0f487124b493f2a2007e82fc8f04b4bf 371 Pfam PF13439 Glycosyltransferase Family 4 56 179 1.2E-9 T 10-11-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A4G23_RS08170 0f487124b493f2a2007e82fc8f04b4bf 371 Gene3D G3DSA:3.40.50.2000 193 333 2.5E-22 T 10-11-2016 A4G23_RS08170 0f487124b493f2a2007e82fc8f04b4bf 371 Pfam PF00534 Glycosyl transferases group 1 188 331 9.3E-27 T 10-11-2016 IPR001296 Glycosyl transferase, family 1 A4G23_RS08170 0f487124b493f2a2007e82fc8f04b4bf 371 SUPERFAMILY SSF53756 87 365 2.29E-51 T 10-11-2016 A4G23_RS12180 0f0ad2b72fb9d1edbdda3b6ea64cdf7a 217 SMART SM00554 120 217 8.5E-32 T 10-11-2016 IPR000782 FAS1 domain A4G23_RS12180 0f0ad2b72fb9d1edbdda3b6ea64cdf7a 217 SUPERFAMILY SSF82153 77 216 8.24E-36 T 10-11-2016 IPR000782 FAS1 domain A4G23_RS12180 0f0ad2b72fb9d1edbdda3b6ea64cdf7a 217 Pfam PF02469 Fasciclin domain 96 216 5.2E-31 T 10-11-2016 IPR000782 FAS1 domain A4G23_RS12180 0f0ad2b72fb9d1edbdda3b6ea64cdf7a 217 Gene3D G3DSA:2.30.180.10 87 215 4.7E-33 T 10-11-2016 IPR000782 FAS1 domain A4G23_RS19945 105ac9c18797eacd73e402db60a16d1c 419 SUPERFAMILY SSF53383 4 417 1.17E-170 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS19945 105ac9c18797eacd73e402db60a16d1c 419 PIRSF PIRSF000412 1 413 2.8E-157 T 10-11-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A4G23_RS19945 105ac9c18797eacd73e402db60a16d1c 419 Pfam PF00464 Serine hydroxymethyltransferase 9 389 3.2E-164 T 10-11-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A4G23_RS19945 105ac9c18797eacd73e402db60a16d1c 419 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 7 417 50.356 T 10-11-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A4G23_RS19945 105ac9c18797eacd73e402db60a16d1c 419 Gene3D G3DSA:3.90.1150.10 284 417 2.3E-45 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS19945 105ac9c18797eacd73e402db60a16d1c 419 Gene3D G3DSA:3.40.640.10 37 283 1.0E-106 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS19945 105ac9c18797eacd73e402db60a16d1c 419 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 222 238 - T 10-11-2016 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0004372|GO:0006544|GO:0006563|GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A4G23_RS07430 7291639db4f3823d89ff5896d5582b5f 535 Pfam PF07690 Major Facilitator Superfamily 36 428 1.6E-53 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS07430 7291639db4f3823d89ff5896d5582b5f 535 SUPERFAMILY SSF103473 267 438 7.85E-75 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS07430 7291639db4f3823d89ff5896d5582b5f 535 SUPERFAMILY SSF103473 498 523 7.85E-75 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS07430 7291639db4f3823d89ff5896d5582b5f 535 SUPERFAMILY SSF103473 12 214 7.85E-75 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS07430 7291639db4f3823d89ff5896d5582b5f 535 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 31 513 8.3E-87 T 10-11-2016 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 A4G23_RS07430 7291639db4f3823d89ff5896d5582b5f 535 Gene3D G3DSA:1.20.1250.20 499 523 3.9E-22 T 10-11-2016 A4G23_RS07430 7291639db4f3823d89ff5896d5582b5f 535 Gene3D G3DSA:1.20.1250.20 290 439 3.9E-22 T 10-11-2016 A4G23_RS07430 7291639db4f3823d89ff5896d5582b5f 535 Gene3D G3DSA:1.20.1250.20 25 216 5.9E-31 T 10-11-2016 A4G23_RS18750 2c59978c6ec4542647ee46bfe0c34b2c 1223 Pfam PF13361 UvrD-like helicase C-terminal domain 723 854 2.2E-20 T 10-11-2016 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 A4G23_RS18750 2c59978c6ec4542647ee46bfe0c34b2c 1223 Pfam PF00580 UvrD/REP helicase N-terminal domain 40 312 4.7E-46 T 10-11-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 A4G23_RS18750 2c59978c6ec4542647ee46bfe0c34b2c 1223 SUPERFAMILY SSF52540 650 870 3.59E-102 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS18750 2c59978c6ec4542647ee46bfe0c34b2c 1223 SUPERFAMILY SSF52540 37 459 3.59E-102 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS18750 2c59978c6ec4542647ee46bfe0c34b2c 1223 Gene3D G3DSA:3.40.50.300 38 176 1.1E-58 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS18750 2c59978c6ec4542647ee46bfe0c34b2c 1223 Gene3D G3DSA:3.40.50.300 222 316 1.1E-58 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS18750 2c59978c6ec4542647ee46bfe0c34b2c 1223 Pfam PF12705 PD-(D/E)XK nuclease superfamily 960 1212 3.4E-36 T 10-11-2016 A4G23_RS18750 2c59978c6ec4542647ee46bfe0c34b2c 1223 Gene3D G3DSA:3.40.50.300 329 450 4.9E-43 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS18750 2c59978c6ec4542647ee46bfe0c34b2c 1223 Gene3D G3DSA:3.40.50.300 772 871 4.9E-43 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS06990 8920365bd11dcfe95649cc9de2977d7d 221 Gene3D G3DSA:1.20.910.10 6 214 1.5E-65 T 10-11-2016 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 A4G23_RS06990 8920365bd11dcfe95649cc9de2977d7d 221 SUPERFAMILY SSF48613 8 215 8.39E-62 T 10-11-2016 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 A4G23_RS06990 8920365bd11dcfe95649cc9de2977d7d 221 Pfam PF01126 Heme oxygenase 9 212 1.4E-65 T 10-11-2016 IPR016053 Haem oxygenase-like GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: R-HSA-189483|Reactome: R-HSA-917937 A4G23_RS06990 8920365bd11dcfe95649cc9de2977d7d 221 PRINTS PR00088 Haem oxygenase signature 69 94 1.1E-33 T 10-11-2016 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: R-HSA-189483|Reactome: R-HSA-917937 A4G23_RS06990 8920365bd11dcfe95649cc9de2977d7d 221 PRINTS PR00088 Haem oxygenase signature 122 143 1.1E-33 T 10-11-2016 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: R-HSA-189483|Reactome: R-HSA-917937 A4G23_RS06990 8920365bd11dcfe95649cc9de2977d7d 221 PRINTS PR00088 Haem oxygenase signature 44 69 1.1E-33 T 10-11-2016 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: R-HSA-189483|Reactome: R-HSA-917937 A4G23_RS06990 8920365bd11dcfe95649cc9de2977d7d 221 PRINTS PR00088 Haem oxygenase signature 166 187 1.1E-33 T 10-11-2016 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: R-HSA-189483|Reactome: R-HSA-917937 A4G23_RS06990 8920365bd11dcfe95649cc9de2977d7d 221 PRINTS PR00088 Haem oxygenase signature 9 34 1.1E-33 T 10-11-2016 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: R-HSA-189483|Reactome: R-HSA-917937 A4G23_RS06990 8920365bd11dcfe95649cc9de2977d7d 221 PRINTS PR00088 Haem oxygenase signature 198 216 1.1E-33 T 10-11-2016 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: R-HSA-189483|Reactome: R-HSA-917937 A4G23_RS06990 8920365bd11dcfe95649cc9de2977d7d 221 PIRSF PIRSF000343 2 220 3.0E-70 T 10-11-2016 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: R-HSA-189483|Reactome: R-HSA-917937 A4G23_RS08630 099f7d93f881f84b46dad886d9b60b3a 815 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 186 200 2.6E-21 T 10-11-2016 A4G23_RS08630 099f7d93f881f84b46dad886d9b60b3a 815 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 292 316 2.6E-21 T 10-11-2016 A4G23_RS08630 099f7d93f881f84b46dad886d9b60b3a 815 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 158 174 2.6E-21 T 10-11-2016 A4G23_RS08630 099f7d93f881f84b46dad886d9b60b3a 815 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 257 269 2.6E-21 T 10-11-2016 A4G23_RS08630 099f7d93f881f84b46dad886d9b60b3a 815 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 260 266 - T 10-11-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A4G23_RS08630 099f7d93f881f84b46dad886d9b60b3a 815 TIGRFAM TIGR00497 hsdM: type I restriction-modification system, M subunit 87 446 1.3E-73 T 10-11-2016 IPR004546 Restriction endonuclease, type I, HsdM GO:0003677|GO:0009007|GO:0009307 A4G23_RS08630 099f7d93f881f84b46dad886d9b60b3a 815 Pfam PF12161 HsdM N-terminal domain 8 119 3.5E-16 T 10-11-2016 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain A4G23_RS08630 099f7d93f881f84b46dad886d9b60b3a 815 Gene3D G3DSA:3.40.50.150 136 348 3.9E-42 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS08630 099f7d93f881f84b46dad886d9b60b3a 815 Pfam PF02384 N-6 DNA Methylase 135 442 5.1E-101 T 10-11-2016 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 A4G23_RS08630 099f7d93f881f84b46dad886d9b60b3a 815 SUPERFAMILY SSF53335 6 488 3.72E-127 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS25890 25eefb0487e4bb057c37912d0edb5ee3 444 Pfam PF12867 DinB superfamily 20 152 1.8E-25 T 10-11-2016 IPR024775 DinB-like domain A4G23_RS25890 25eefb0487e4bb057c37912d0edb5ee3 444 Hamap MF_02035 Hercynine oxygenase [egtB]. 1 443 51.603 T 10-11-2016 IPR032890 Hercynine oxygenase, Actinobacteria GO:0016491|GO:0052699 KEGG: 00340+1.14.99.50|MetaCyc: PWY-7255 A4G23_RS25890 25eefb0487e4bb057c37912d0edb5ee3 444 SUPERFAMILY SSF56436 184 443 1.15E-76 T 10-11-2016 IPR016187 C-type lectin fold A4G23_RS25890 25eefb0487e4bb057c37912d0edb5ee3 444 SUPERFAMILY SSF109854 6 151 3.07E-22 T 10-11-2016 A4G23_RS25890 25eefb0487e4bb057c37912d0edb5ee3 444 Gene3D G3DSA:1.20.120.450 6 127 1.5E-7 T 10-11-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase A4G23_RS25890 25eefb0487e4bb057c37912d0edb5ee3 444 Gene3D G3DSA:3.90.1580.10 180 443 1.2E-75 T 10-11-2016 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 A4G23_RS25890 25eefb0487e4bb057c37912d0edb5ee3 444 Pfam PF03781 Sulfatase-modifying factor enzyme 1 181 441 1.9E-63 T 10-11-2016 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 A4G23_RS25890 25eefb0487e4bb057c37912d0edb5ee3 444 TIGRFAM TIGR03440 egtB_TIGR03440: ergothioneine biosynthesis protein EgtB 19 440 2.1E-135 T 10-11-2016 IPR017806 Ergothioneine biosynthesis protein EgtB GO:0052699 KEGG: 00340+1.14.99.50|MetaCyc: PWY-7255 A4G23_RS15605 58642b61c3b536d819394868702b20b3 238 SUPERFAMILY SSF88946 60 165 3.92E-27 T 10-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS15605 58642b61c3b536d819394868702b20b3 238 Gene3D G3DSA:1.10.1740.10 63 171 2.6E-29 T 10-11-2016 A4G23_RS15605 58642b61c3b536d819394868702b20b3 238 Pfam PF08281 Sigma-70, region 4 178 229 9.6E-14 T 10-11-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS15605 58642b61c3b536d819394868702b20b3 238 SUPERFAMILY SSF88659 163 233 1.81E-13 T 10-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS15605 58642b61c3b536d819394868702b20b3 238 Gene3D G3DSA:1.10.10.10 172 235 6.0E-15 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS15605 58642b61c3b536d819394868702b20b3 238 Pfam PF04542 Sigma-70 region 2 79 146 6.5E-18 T 10-11-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS15605 58642b61c3b536d819394868702b20b3 238 TIGRFAM TIGR02952 Sig70_famx2: RNA polymerase sigma-70 factor, TIGR02952 family 64 233 1.9E-78 T 10-11-2016 IPR014298 RNA polymerase sigma-X type A4G23_RS15605 58642b61c3b536d819394868702b20b3 238 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 74 231 1.1E-29 T 10-11-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS24740 458826f4421bcf739edb5224649f3f63 381 SUPERFAMILY SSF47203 233 381 7.57E-44 T 10-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4G23_RS24740 458826f4421bcf739edb5224649f3f63 381 Gene3D G3DSA:1.10.540.10 6 120 7.3E-36 T 10-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 A4G23_RS24740 458826f4421bcf739edb5224649f3f63 381 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 119 8.6E-35 T 10-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 A4G23_RS24740 458826f4421bcf739edb5224649f3f63 381 SUPERFAMILY SSF56645 5 242 4.45E-83 T 10-11-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 A4G23_RS24740 458826f4421bcf739edb5224649f3f63 381 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 338 357 - T 10-11-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A4G23_RS24740 458826f4421bcf739edb5224649f3f63 381 Gene3D G3DSA:2.40.110.10 123 218 3.0E-40 T 10-11-2016 A4G23_RS24740 458826f4421bcf739edb5224649f3f63 381 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 218 6.8E-26 T 10-11-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 A4G23_RS24740 458826f4421bcf739edb5224649f3f63 381 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 125 137 - T 10-11-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A4G23_RS24740 458826f4421bcf739edb5224649f3f63 381 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 236 380 1.6E-41 T 10-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4G23_RS24740 458826f4421bcf739edb5224649f3f63 381 Gene3D G3DSA:1.20.140.10 219 381 2.2E-55 T 10-11-2016 A4G23_RS16625 dc4acfa38aa75758c4a3c30950b54c45 93 Gene3D G3DSA:3.30.860.10 1 92 1.8E-41 T 10-11-2016 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS16625 dc4acfa38aa75758c4a3c30950b54c45 93 SUPERFAMILY SSF54570 3 84 2.09E-35 T 10-11-2016 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS16625 dc4acfa38aa75758c4a3c30950b54c45 93 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 2.1E-24 T 10-11-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS16625 dc4acfa38aa75758c4a3c30950b54c45 93 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 2.1E-24 T 10-11-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS16625 dc4acfa38aa75758c4a3c30950b54c45 93 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 2.1E-24 T 10-11-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS16625 dc4acfa38aa75758c4a3c30950b54c45 93 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.188 T 10-11-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS16625 dc4acfa38aa75758c4a3c30950b54c45 93 PIRSF PIRSF002144 1 93 6.9E-32 T 10-11-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS16625 dc4acfa38aa75758c4a3c30950b54c45 93 Pfam PF00203 Ribosomal protein S19 3 83 1.6E-37 T 10-11-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS16625 dc4acfa38aa75758c4a3c30950b54c45 93 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 92 6.2E-47 T 10-11-2016 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 A4G23_RS16625 dc4acfa38aa75758c4a3c30950b54c45 93 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 10-11-2016 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS05670 553bda70d1451f4413c4c64d8ff9a168 258 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 8 247 1.1E-53 T 10-11-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4G23_RS05670 553bda70d1451f4413c4c64d8ff9a168 258 Gene3D G3DSA:3.20.20.70 4 255 1.9E-107 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS05670 553bda70d1451f4413c4c64d8ff9a168 258 ProSitePatterns PS00171 Triosephosphate isomerase active site. 171 181 - T 10-11-2016 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4G23_RS05670 553bda70d1451f4413c4c64d8ff9a168 258 Pfam PF00121 Triosephosphate isomerase 7 253 4.0E-89 T 10-11-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4G23_RS05670 553bda70d1451f4413c4c64d8ff9a168 258 SUPERFAMILY SSF51351 3 255 7.33E-93 T 10-11-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4G23_RS05670 553bda70d1451f4413c4c64d8ff9a168 258 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 4 256 39.85 T 10-11-2016 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4G23_RS26010 b9fb64d3ddb67efcbdda33ac35287d79 484 PRINTS PR01036 Tetracycline resistance protein TetB signature 136 156 2.0E-6 T 10-11-2016 A4G23_RS26010 b9fb64d3ddb67efcbdda33ac35287d79 484 PRINTS PR01036 Tetracycline resistance protein TetB signature 166 190 2.0E-6 T 10-11-2016 A4G23_RS26010 b9fb64d3ddb67efcbdda33ac35287d79 484 PRINTS PR01036 Tetracycline resistance protein TetB signature 323 347 2.0E-6 T 10-11-2016 A4G23_RS26010 b9fb64d3ddb67efcbdda33ac35287d79 484 PRINTS PR01036 Tetracycline resistance protein TetB signature 45 69 2.0E-6 T 10-11-2016 A4G23_RS26010 b9fb64d3ddb67efcbdda33ac35287d79 484 SUPERFAMILY SSF103473 269 465 6.54E-56 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS26010 b9fb64d3ddb67efcbdda33ac35287d79 484 SUPERFAMILY SSF103473 37 225 6.54E-56 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS26010 b9fb64d3ddb67efcbdda33ac35287d79 484 Gene3D G3DSA:1.20.1250.20 294 462 2.2E-22 T 10-11-2016 A4G23_RS26010 b9fb64d3ddb67efcbdda33ac35287d79 484 Pfam PF07690 Major Facilitator Superfamily 48 431 1.1E-45 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS26010 b9fb64d3ddb67efcbdda33ac35287d79 484 Gene3D G3DSA:1.20.1250.20 39 221 1.2E-25 T 10-11-2016 A4G23_RS02155 bb22eacbff782f1e791e2f6d28450c91 489 Pfam PF03664 Glycosyl hydrolase family 62 186 459 2.9E-148 T 10-11-2016 IPR005193 Glycoside hydrolase, family 62, arabinosidase GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 A4G23_RS02155 bb22eacbff782f1e791e2f6d28450c91 489 SMART SM00458 41 177 2.4E-9 T 10-11-2016 IPR000772 Ricin B, lectin domain A4G23_RS02155 bb22eacbff782f1e791e2f6d28450c91 489 SUPERFAMILY SSF50370 38 176 1.39E-47 T 10-11-2016 IPR000772 Ricin B, lectin domain A4G23_RS02155 bb22eacbff782f1e791e2f6d28450c91 489 SUPERFAMILY SSF75005 205 480 4.08E-29 T 10-11-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain A4G23_RS02155 bb22eacbff782f1e791e2f6d28450c91 489 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 123 181 1.8E-15 T 10-11-2016 IPR000772 Ricin B, lectin domain A4G23_RS02155 bb22eacbff782f1e791e2f6d28450c91 489 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 37 117 6.1E-22 T 10-11-2016 IPR000772 Ricin B, lectin domain A4G23_RS02155 bb22eacbff782f1e791e2f6d28450c91 489 Gene3D G3DSA:2.80.10.50 42 177 2.1E-39 T 10-11-2016 A4G23_RS06850 edbea378c97d5564979a80b4cbfe88b5 550 SMART SM00642 27 418 2.0E-132 T 10-11-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A4G23_RS06850 edbea378c97d5564979a80b4cbfe88b5 550 Pfam PF11941 Domain of unknown function (DUF3459) 467 548 1.8E-7 T 10-11-2016 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) A4G23_RS06850 edbea378c97d5564979a80b4cbfe88b5 550 Gene3D G3DSA:3.90.400.10 119 191 5.6E-30 T 10-11-2016 A4G23_RS06850 edbea378c97d5564979a80b4cbfe88b5 550 Pfam PF00128 Alpha amylase, catalytic domain 42 396 8.3E-84 T 10-11-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A4G23_RS06850 edbea378c97d5564979a80b4cbfe88b5 550 Gene3D G3DSA:3.20.20.80 192 482 9.1E-112 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS06850 edbea378c97d5564979a80b4cbfe88b5 550 Gene3D G3DSA:3.20.20.80 19 118 9.1E-112 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS06850 edbea378c97d5564979a80b4cbfe88b5 550 SUPERFAMILY SSF51445 19 481 8.0E-133 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS08305 5e4439b51d2db146848b6c5ee4dd1a3c 219 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 20 211 39.758 T 10-11-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4G23_RS08305 5e4439b51d2db146848b6c5ee4dd1a3c 219 Gene3D G3DSA:3.90.226.10 30 214 5.6E-75 T 10-11-2016 IPR029045 ClpP/crotonase-like domain A4G23_RS08305 5e4439b51d2db146848b6c5ee4dd1a3c 219 SUPERFAMILY SSF52096 28 212 2.31E-62 T 10-11-2016 IPR029045 ClpP/crotonase-like domain A4G23_RS08305 5e4439b51d2db146848b6c5ee4dd1a3c 219 PRINTS PR00127 Clp protease catalytic subunit P signature 76 96 2.0E-43 T 10-11-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4G23_RS08305 5e4439b51d2db146848b6c5ee4dd1a3c 219 PRINTS PR00127 Clp protease catalytic subunit P signature 36 51 2.0E-43 T 10-11-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4G23_RS08305 5e4439b51d2db146848b6c5ee4dd1a3c 219 PRINTS PR00127 Clp protease catalytic subunit P signature 186 205 2.0E-43 T 10-11-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4G23_RS08305 5e4439b51d2db146848b6c5ee4dd1a3c 219 PRINTS PR00127 Clp protease catalytic subunit P signature 107 124 2.0E-43 T 10-11-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4G23_RS08305 5e4439b51d2db146848b6c5ee4dd1a3c 219 PRINTS PR00127 Clp protease catalytic subunit P signature 128 147 2.0E-43 T 10-11-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4G23_RS08305 5e4439b51d2db146848b6c5ee4dd1a3c 219 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 129 142 - T 10-11-2016 IPR033135 ClpP, histidine active site A4G23_RS08305 5e4439b51d2db146848b6c5ee4dd1a3c 219 Pfam PF00574 Clp protease 30 210 3.1E-77 T 10-11-2016 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA A4G23_RS08305 5e4439b51d2db146848b6c5ee4dd1a3c 219 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 107 118 - T 10-11-2016 IPR018215 ClpP, Ser active site A4G23_RS06425 f8fe1412cb2b41ee237ed508ba5a5e02 407 Gene3D G3DSA:3.30.565.10 301 402 7.7E-12 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS06425 f8fe1412cb2b41ee237ed508ba5a5e02 407 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 310 400 1.0E-7 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS06425 f8fe1412cb2b41ee237ed508ba5a5e02 407 Pfam PF07730 Histidine kinase 189 238 1.7E-7 T 10-11-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4G23_RS06425 f8fe1412cb2b41ee237ed508ba5a5e02 407 SUPERFAMILY SSF55874 285 401 1.07E-15 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS11170 458a1f11dc1f0b67aed7f4c83e2f0210 529 Gene3D G3DSA:1.20.1250.20 35 231 1.6E-24 T 10-11-2016 A4G23_RS11170 458a1f11dc1f0b67aed7f4c83e2f0210 529 Pfam PF07690 Major Facilitator Superfamily 44 298 1.1E-24 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS11170 458a1f11dc1f0b67aed7f4c83e2f0210 529 Pfam PF07690 Major Facilitator Superfamily 312 493 2.1E-12 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS11170 458a1f11dc1f0b67aed7f4c83e2f0210 529 Gene3D G3DSA:1.20.1250.20 301 478 1.0E-20 T 10-11-2016 A4G23_RS11170 458a1f11dc1f0b67aed7f4c83e2f0210 529 SUPERFAMILY SSF103473 281 479 1.7E-56 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS11170 458a1f11dc1f0b67aed7f4c83e2f0210 529 SUPERFAMILY SSF103473 20 232 1.7E-56 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS12480 d3a105cc04ad201c94203d073129360e 481 SUPERFAMILY SSF47384 235 321 2.35E-12 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS12480 d3a105cc04ad201c94203d073129360e 481 PRINTS PR00344 Bacterial sensor protein C-terminal signature 430 448 1.8E-12 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS12480 d3a105cc04ad201c94203d073129360e 481 PRINTS PR00344 Bacterial sensor protein C-terminal signature 454 467 1.8E-12 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS12480 d3a105cc04ad201c94203d073129360e 481 PRINTS PR00344 Bacterial sensor protein C-terminal signature 415 425 1.8E-12 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS12480 d3a105cc04ad201c94203d073129360e 481 PRINTS PR00344 Bacterial sensor protein C-terminal signature 397 411 1.8E-12 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS12480 d3a105cc04ad201c94203d073129360e 481 Pfam PF00672 HAMP domain 180 246 3.5E-15 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS12480 d3a105cc04ad201c94203d073129360e 481 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 367 467 1.3E-21 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS12480 d3a105cc04ad201c94203d073129360e 481 SMART SM00388 252 323 1.9E-11 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS12480 d3a105cc04ad201c94203d073129360e 481 Pfam PF00512 His Kinase A (phospho-acceptor) domain 253 322 1.2E-12 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS12480 d3a105cc04ad201c94203d073129360e 481 Gene3D G3DSA:3.30.565.10 329 473 2.9E-33 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS12480 d3a105cc04ad201c94203d073129360e 481 SMART SM00304 198 251 1.2E-13 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS12480 d3a105cc04ad201c94203d073129360e 481 SUPERFAMILY SSF158472 201 248 8.11E-8 T 10-11-2016 A4G23_RS12480 d3a105cc04ad201c94203d073129360e 481 Gene3D G3DSA:1.10.287.130 245 319 2.3E-13 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS12480 d3a105cc04ad201c94203d073129360e 481 SMART SM00387 364 470 5.8E-33 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS12480 d3a105cc04ad201c94203d073129360e 481 SUPERFAMILY SSF55874 327 471 1.03E-33 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS17445 05eb18250a2076b816e54760331fac3e 234 Pfam PF00106 short chain dehydrogenase 7 190 1.6E-34 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS17445 05eb18250a2076b816e54760331fac3e 234 Gene3D G3DSA:3.40.50.720 6 194 9.3E-46 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS17445 05eb18250a2076b816e54760331fac3e 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 6.7E-11 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS17445 05eb18250a2076b816e54760331fac3e 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 6.7E-11 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS17445 05eb18250a2076b816e54760331fac3e 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 6.7E-11 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS17445 05eb18250a2076b816e54760331fac3e 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 6.7E-11 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS17445 05eb18250a2076b816e54760331fac3e 234 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 10-11-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4G23_RS17445 05eb18250a2076b816e54760331fac3e 234 SUPERFAMILY SSF51735 5 213 1.69E-44 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS17240 8fe4f888782b12f65e4e479ef5481091 284 SUPERFAMILY SSF51735 122 281 1.51E-41 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS17240 8fe4f888782b12f65e4e479ef5481091 284 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 120 3.5E-31 T 10-11-2016 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A4G23_RS17240 8fe4f888782b12f65e4e479ef5481091 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 5.0E-60 T 10-11-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A4G23_RS17240 8fe4f888782b12f65e4e479ef5481091 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 205 234 5.0E-60 T 10-11-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A4G23_RS17240 8fe4f888782b12f65e4e479ef5481091 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 5.0E-60 T 10-11-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A4G23_RS17240 8fe4f888782b12f65e4e479ef5481091 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 256 274 5.0E-60 T 10-11-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A4G23_RS17240 8fe4f888782b12f65e4e479ef5481091 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 5.0E-60 T 10-11-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A4G23_RS17240 8fe4f888782b12f65e4e479ef5481091 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 5.0E-60 T 10-11-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A4G23_RS17240 8fe4f888782b12f65e4e479ef5481091 284 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 123 282 4.3E-61 T 10-11-2016 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A4G23_RS17240 8fe4f888782b12f65e4e479ef5481091 284 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 283 35.199 T 10-11-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A4G23_RS17240 8fe4f888782b12f65e4e479ef5481091 284 Gene3D G3DSA:3.40.50.720 139 264 7.9E-44 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS17240 8fe4f888782b12f65e4e479ef5481091 284 SUPERFAMILY SSF53223 1 121 3.45E-33 T 10-11-2016 A4G23_RS17240 8fe4f888782b12f65e4e479ef5481091 284 Gene3D G3DSA:3.40.192.10 7 138 2.8E-41 T 10-11-2016 A4G23_RS04645 39027bfd22c91a42a193e0e244f9918f 301 Pfam PF00892 EamA-like transporter family 159 292 5.3E-22 T 10-11-2016 IPR000620 EamA domain GO:0016020|GO:0016021 A4G23_RS04645 39027bfd22c91a42a193e0e244f9918f 301 Pfam PF00892 EamA-like transporter family 18 146 5.4E-17 T 10-11-2016 IPR000620 EamA domain GO:0016020|GO:0016021 A4G23_RS04645 39027bfd22c91a42a193e0e244f9918f 301 SUPERFAMILY SSF103481 59 148 3.01E-14 T 10-11-2016 A4G23_RS04645 39027bfd22c91a42a193e0e244f9918f 301 SUPERFAMILY SSF103481 196 296 5.36E-16 T 10-11-2016 A4G23_RS04650 a08b8b737a7013665ecda01fd01e1e37 360 Pfam PF00107 Zinc-binding dehydrogenase 190 310 1.9E-27 T 10-11-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A4G23_RS04650 a08b8b737a7013665ecda01fd01e1e37 360 SUPERFAMILY SSF51735 152 324 1.39E-41 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS04650 a08b8b737a7013665ecda01fd01e1e37 360 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 146 9.7E-24 T 10-11-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A4G23_RS04650 a08b8b737a7013665ecda01fd01e1e37 360 SMART SM00829 12 358 8.9E-10 T 10-11-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A4G23_RS04650 a08b8b737a7013665ecda01fd01e1e37 360 Gene3D G3DSA:3.40.50.720 183 302 7.3E-38 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS04650 a08b8b737a7013665ecda01fd01e1e37 360 SUPERFAMILY SSF50129 3 185 1.4E-50 T 10-11-2016 IPR011032 GroES-like A4G23_RS04650 a08b8b737a7013665ecda01fd01e1e37 360 Gene3D G3DSA:3.90.180.10 3 182 3.9E-55 T 10-11-2016 IPR011032 GroES-like A4G23_RS04650 a08b8b737a7013665ecda01fd01e1e37 360 SUPERFAMILY SSF50129 312 360 8.76E-5 T 10-11-2016 IPR011032 GroES-like A4G23_RS04650 a08b8b737a7013665ecda01fd01e1e37 360 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 60 74 - T 10-11-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 A4G23_RS25730 eef7c5e938af35023388532648d14abe 248 Gene3D G3DSA:2.40.50.40 140 206 2.6E-17 T 10-11-2016 A4G23_RS25730 eef7c5e938af35023388532648d14abe 248 SMART SM00850 148 243 1.7E-29 T 10-11-2016 IPR007492 LytTR DNA-binding domain GO:0003677 A4G23_RS25730 eef7c5e938af35023388532648d14abe 248 Pfam PF00072 Response regulator receiver domain 4 123 4.2E-16 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS25730 eef7c5e938af35023388532648d14abe 248 SMART SM00448 2 122 3.4E-16 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS25730 eef7c5e938af35023388532648d14abe 248 Pfam PF04397 LytTr DNA-binding domain 150 242 1.4E-22 T 10-11-2016 IPR007492 LytTR DNA-binding domain GO:0003677 A4G23_RS25730 eef7c5e938af35023388532648d14abe 248 SUPERFAMILY SSF52172 1 137 6.12E-25 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS25730 eef7c5e938af35023388532648d14abe 248 Gene3D G3DSA:3.40.50.2300 1 127 7.5E-25 T 10-11-2016 A4G23_RS17565 0400c4080a1511e257676b9c7b004f7d 407 Gene3D G3DSA:3.40.630.10 315 401 6.1E-88 T 10-11-2016 A4G23_RS17565 0400c4080a1511e257676b9c7b004f7d 407 Gene3D G3DSA:3.40.630.10 22 195 6.1E-88 T 10-11-2016 A4G23_RS17565 0400c4080a1511e257676b9c7b004f7d 407 Pfam PF07687 Peptidase dimerisation domain 203 294 1.6E-5 T 10-11-2016 IPR011650 Peptidase M20, dimerisation domain A4G23_RS17565 0400c4080a1511e257676b9c7b004f7d 407 SUPERFAMILY SSF55031 199 316 2.99E-23 T 10-11-2016 IPR011650 Peptidase M20, dimerisation domain A4G23_RS17565 0400c4080a1511e257676b9c7b004f7d 407 Gene3D G3DSA:3.30.70.360 199 314 1.3E-30 T 10-11-2016 IPR011650 Peptidase M20, dimerisation domain A4G23_RS17565 0400c4080a1511e257676b9c7b004f7d 407 Pfam PF01546 Peptidase family M20/M25/M40 86 399 5.4E-28 T 10-11-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A4G23_RS17565 0400c4080a1511e257676b9c7b004f7d 407 PIRSF PIRSF005962 17 405 9.9E-96 T 10-11-2016 IPR017439 Amidohydrolase GO:0016787 A4G23_RS17565 0400c4080a1511e257676b9c7b004f7d 407 SUPERFAMILY SSF53187 315 400 1.05E-65 T 10-11-2016 A4G23_RS17565 0400c4080a1511e257676b9c7b004f7d 407 SUPERFAMILY SSF53187 21 214 1.05E-65 T 10-11-2016 A4G23_RS17565 0400c4080a1511e257676b9c7b004f7d 407 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 28 392 1.3E-103 T 10-11-2016 IPR017439 Amidohydrolase GO:0016787 A4G23_RS22860 4dc20b89867f30b41410c5cd2c36839a 307 Gene3D G3DSA:1.10.3720.10 57 303 2.2E-58 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS22860 4dc20b89867f30b41410c5cd2c36839a 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 304 1.8E-12 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS22860 4dc20b89867f30b41410c5cd2c36839a 307 SUPERFAMILY SSF161098 52 294 5.76E-49 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS22400 a81f1b70d524d808d3d423bf430087df 554 SUPERFAMILY SSF55469 368 413 6.91E-13 T 10-11-2016 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4G23_RS22400 a81f1b70d524d808d3d423bf430087df 554 SUPERFAMILY SSF55469 454 546 6.91E-13 T 10-11-2016 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4G23_RS22400 a81f1b70d524d808d3d423bf430087df 554 Gene3D G3DSA:3.40.109.10 212 270 3.3E-4 T 10-11-2016 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4G23_RS22400 a81f1b70d524d808d3d423bf430087df 554 Gene3D G3DSA:3.40.109.10 455 546 3.3E-11 T 10-11-2016 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4G23_RS22400 a81f1b70d524d808d3d423bf430087df 554 Pfam PF00881 Nitroreductase family 438 541 2.8E-13 T 10-11-2016 IPR029479 Nitroreductase Reactome: R-HSA-209968 A4G23_RS22400 a81f1b70d524d808d3d423bf430087df 554 SUPERFAMILY SSF55469 208 267 4.97E-5 T 10-11-2016 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4G23_RS25400 ccdd85d385ed457f62392516fb7caaeb 321 Gene3D G3DSA:3.40.33.10 196 316 3.2E-12 T 10-11-2016 IPR014044 CAP domain A4G23_RS25400 ccdd85d385ed457f62392516fb7caaeb 321 SUPERFAMILY SSF55797 197 318 2.62E-23 T 10-11-2016 IPR014044 CAP domain A4G23_RS25400 ccdd85d385ed457f62392516fb7caaeb 321 Pfam PF00188 Cysteine-rich secretory protein family 203 317 9.7E-20 T 10-11-2016 IPR014044 CAP domain A4G23_RS11380 3ec87fcbe640e7dda8e7269bcd0d9e46 843 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 133 145 - T 10-11-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 A4G23_RS11380 3ec87fcbe640e7dda8e7269bcd0d9e46 843 Pfam PF13360 PQQ-like domain 689 835 8.8E-21 T 10-11-2016 IPR002372 Pyrrolo-quinoline quinone repeat A4G23_RS11380 3ec87fcbe640e7dda8e7269bcd0d9e46 843 Pfam PF13360 PQQ-like domain 519 675 4.9E-19 T 10-11-2016 IPR002372 Pyrrolo-quinoline quinone repeat A4G23_RS11380 3ec87fcbe640e7dda8e7269bcd0d9e46 843 Gene3D G3DSA:1.10.510.10 98 262 1.1E-39 T 10-11-2016 A4G23_RS11380 3ec87fcbe640e7dda8e7269bcd0d9e46 843 SMART SM00220 15 270 9.7E-40 T 10-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4G23_RS11380 3ec87fcbe640e7dda8e7269bcd0d9e46 843 SUPERFAMILY SSF50998 747 837 6.43E-12 T 10-11-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily A4G23_RS11380 3ec87fcbe640e7dda8e7269bcd0d9e46 843 Gene3D G3DSA:2.140.10.10 529 834 2.0E-61 T 10-11-2016 IPR027295 Quinoprotein alcohol dehydrogenase-like domain A4G23_RS11380 3ec87fcbe640e7dda8e7269bcd0d9e46 843 Gene3D G3DSA:2.140.10.10 448 495 2.0E-61 T 10-11-2016 IPR027295 Quinoprotein alcohol dehydrogenase-like domain A4G23_RS11380 3ec87fcbe640e7dda8e7269bcd0d9e46 843 SMART SM00564 555 587 11.0 T 10-11-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A4G23_RS11380 3ec87fcbe640e7dda8e7269bcd0d9e46 843 SMART SM00564 645 675 180.0 T 10-11-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A4G23_RS11380 3ec87fcbe640e7dda8e7269bcd0d9e46 843 SMART SM00564 810 841 4.1 T 10-11-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A4G23_RS11380 3ec87fcbe640e7dda8e7269bcd0d9e46 843 SMART SM00564 600 630 2.9E-5 T 10-11-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A4G23_RS11380 3ec87fcbe640e7dda8e7269bcd0d9e46 843 SMART SM00564 690 721 3.4E-6 T 10-11-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A4G23_RS11380 3ec87fcbe640e7dda8e7269bcd0d9e46 843 SMART SM00564 483 512 15.0 T 10-11-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A4G23_RS11380 3ec87fcbe640e7dda8e7269bcd0d9e46 843 SMART SM00564 513 548 140.0 T 10-11-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A4G23_RS11380 3ec87fcbe640e7dda8e7269bcd0d9e46 843 SMART SM00564 730 761 32.0 T 10-11-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A4G23_RS11380 3ec87fcbe640e7dda8e7269bcd0d9e46 843 SMART SM00564 770 801 1.0 T 10-11-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A4G23_RS11380 3ec87fcbe640e7dda8e7269bcd0d9e46 843 Pfam PF00069 Protein kinase domain 15 261 1.1E-37 T 10-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4G23_RS11380 3ec87fcbe640e7dda8e7269bcd0d9e46 843 SUPERFAMILY SSF50998 461 498 1.03E-38 T 10-11-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily A4G23_RS11380 3ec87fcbe640e7dda8e7269bcd0d9e46 843 SUPERFAMILY SSF50998 532 764 1.03E-38 T 10-11-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily A4G23_RS11380 3ec87fcbe640e7dda8e7269bcd0d9e46 843 Gene3D G3DSA:3.30.200.20 6 81 1.3E-12 T 10-11-2016 A4G23_RS11380 3ec87fcbe640e7dda8e7269bcd0d9e46 843 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 21 43 - T 10-11-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 A4G23_RS11380 3ec87fcbe640e7dda8e7269bcd0d9e46 843 Pfam PF13570 PQQ-like domain 471 504 7.5E-4 T 10-11-2016 IPR025666 Pyrrolo-quinoline quinone-like domain A4G23_RS11380 3ec87fcbe640e7dda8e7269bcd0d9e46 843 SUPERFAMILY SSF56112 11 318 2.02E-62 T 10-11-2016 IPR011009 Protein kinase-like domain A4G23_RS24295 d76a2d04320c07d411c4f6b8b3b0ead5 284 Pfam PF00440 Bacterial regulatory proteins, tetR family 44 83 3.8E-17 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS24295 d76a2d04320c07d411c4f6b8b3b0ead5 284 Gene3D G3DSA:1.10.10.60 38 81 3.5E-19 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS24295 d76a2d04320c07d411c4f6b8b3b0ead5 284 Gene3D G3DSA:1.10.357.10 82 222 6.5E-27 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS24295 d76a2d04320c07d411c4f6b8b3b0ead5 284 SUPERFAMILY SSF46689 32 88 3.45E-16 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS24295 d76a2d04320c07d411c4f6b8b3b0ead5 284 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 63 86 1.6E-9 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS24295 d76a2d04320c07d411c4f6b8b3b0ead5 284 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 55 1.6E-9 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS24295 d76a2d04320c07d411c4f6b8b3b0ead5 284 ProSitePatterns PS01081 TetR-type HTH domain signature. 54 85 - T 10-11-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A4G23_RS17160 db285ff6e4ac5d18419da4d69edd1505 296 Gene3D G3DSA:3.40.50.261 126 291 1.8E-67 T 10-11-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4G23_RS17160 db285ff6e4ac5d18419da4d69edd1505 296 Pfam PF02629 CoA binding domain 6 103 2.1E-26 T 10-11-2016 IPR003781 CoA-binding GO:0048037 A4G23_RS17160 db285ff6e4ac5d18419da4d69edd1505 296 SUPERFAMILY SSF52210 129 290 6.28E-47 T 10-11-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4G23_RS17160 db285ff6e4ac5d18419da4d69edd1505 296 PIRSF PIRSF001553 1 295 2.3E-115 T 10-11-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 A4G23_RS17160 db285ff6e4ac5d18419da4d69edd1505 296 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 240 253 - T 10-11-2016 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site A4G23_RS17160 db285ff6e4ac5d18419da4d69edd1505 296 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 3 292 2.4E-127 T 10-11-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 A4G23_RS17160 db285ff6e4ac5d18419da4d69edd1505 296 PRINTS PR01798 Succinyl-CoA synthase signature 86 103 1.6E-34 T 10-11-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 A4G23_RS17160 db285ff6e4ac5d18419da4d69edd1505 296 PRINTS PR01798 Succinyl-CoA synthase signature 212 225 1.6E-34 T 10-11-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 A4G23_RS17160 db285ff6e4ac5d18419da4d69edd1505 296 PRINTS PR01798 Succinyl-CoA synthase signature 244 261 1.6E-34 T 10-11-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 A4G23_RS17160 db285ff6e4ac5d18419da4d69edd1505 296 PRINTS PR01798 Succinyl-CoA synthase signature 181 199 1.6E-34 T 10-11-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 A4G23_RS17160 db285ff6e4ac5d18419da4d69edd1505 296 Pfam PF00549 CoA-ligase 158 275 2.0E-14 T 10-11-2016 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4G23_RS17160 db285ff6e4ac5d18419da4d69edd1505 296 SUPERFAMILY SSF51735 1 128 4.3E-37 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS17160 db285ff6e4ac5d18419da4d69edd1505 296 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 158 185 - T 10-11-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 A4G23_RS17160 db285ff6e4ac5d18419da4d69edd1505 296 SMART SM00881 4 104 7.9E-31 T 10-11-2016 IPR003781 CoA-binding GO:0048037 A4G23_RS17160 db285ff6e4ac5d18419da4d69edd1505 296 Gene3D G3DSA:3.40.50.720 3 125 2.5E-47 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS19250 a7669b9f314081cd7c4f24450be15587 356 Pfam PF13384 Homeodomain-like domain 301 334 8.0E-6 T 10-11-2016 A4G23_RS19250 a7669b9f314081cd7c4f24450be15587 356 Gene3D G3DSA:1.10.10.10 296 354 7.1E-12 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS19250 a7669b9f314081cd7c4f24450be15587 356 SUPERFAMILY SSF46894 296 355 4.08E-10 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS19250 a7669b9f314081cd7c4f24450be15587 356 Gene3D G3DSA:1.10.10.10 8 70 4.5E-6 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS19250 a7669b9f314081cd7c4f24450be15587 356 SMART SM00421 298 348 3.9E-6 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS19250 a7669b9f314081cd7c4f24450be15587 356 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 9 57 3.6E-8 T 10-11-2016 IPR002831 Transcription regulator TrmB, N-terminal A4G23_RS14620 dfb85e5cae24720abd3d40987b30b9c1 153 Pfam PF00583 Acetyltransferase (GNAT) family 54 132 4.0E-10 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS14620 dfb85e5cae24720abd3d40987b30b9c1 153 SUPERFAMILY SSF55729 21 152 1.42E-21 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS14620 dfb85e5cae24720abd3d40987b30b9c1 153 Gene3D G3DSA:3.40.630.30 22 138 3.7E-18 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS06520 fa2c1721c6d32d5ca448c31a2cf51712 93 Pfam PF01037 Lrp/AsnC ligand binding domain 6 77 1.5E-15 T 10-11-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A4G23_RS06520 fa2c1721c6d32d5ca448c31a2cf51712 93 Gene3D G3DSA:3.30.70.920 3 78 5.5E-25 T 10-11-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A4G23_RS06520 fa2c1721c6d32d5ca448c31a2cf51712 93 SUPERFAMILY SSF54909 2 78 1.21E-18 T 10-11-2016 IPR011008 Dimeric alpha-beta barrel A4G23_RS18335 74c348147f197827644769c24a9e2b5a 89 SUPERFAMILY SSF143120 7 57 1.83E-11 T 10-11-2016 A4G23_RS18335 74c348147f197827644769c24a9e2b5a 89 Gene3D G3DSA:3.40.1620.10 9 55 1.6E-16 T 10-11-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM A4G23_RS18335 74c348147f197827644769c24a9e2b5a 89 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 9 54 3.1E-11 T 10-11-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM A4G23_RS18335 74c348147f197827644769c24a9e2b5a 89 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 9 57 1.2E-12 T 10-11-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM A4G23_RS23200 63037a19bef8726085ccc47301afd910 189 Pfam PF13508 Acetyltransferase (GNAT) domain 76 166 3.1E-6 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS23200 63037a19bef8726085ccc47301afd910 189 Gene3D G3DSA:3.40.630.30 57 171 6.3E-14 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS23200 63037a19bef8726085ccc47301afd910 189 SUPERFAMILY SSF55729 47 171 1.39E-17 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS01685 255e503dd68ab9b5596456870f039107 222 Gene3D G3DSA:3.40.50.150 15 199 3.2E-36 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS01685 255e503dd68ab9b5596456870f039107 222 SUPERFAMILY SSF53335 15 208 1.22E-38 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS01685 255e503dd68ab9b5596456870f039107 222 Pfam PF13649 Methyltransferase domain 61 151 1.2E-19 T 10-11-2016 A4G23_RS11870 d9976af8bf13ad64c4a702104514b375 441 Gene3D G3DSA:1.20.1250.20 89 241 8.2E-4 T 10-11-2016 A4G23_RS11870 d9976af8bf13ad64c4a702104514b375 441 Pfam PF07690 Major Facilitator Superfamily 87 404 7.9E-10 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS11870 d9976af8bf13ad64c4a702104514b375 441 SUPERFAMILY SSF103473 88 432 2.75E-15 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS05775 f1778c3c2356e01ad7dd540bca24cf57 210 Gene3D G3DSA:3.40.50.300 20 197 3.1E-12 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS13110 cdeae7631678173c6adebc9a6c9e8c66 225 Gene3D G3DSA:3.40.1580.10 37 85 4.8E-5 T 10-11-2016 IPR018958 SMI1/KNR4-like domain A4G23_RS13110 cdeae7631678173c6adebc9a6c9e8c66 225 SUPERFAMILY SSF160631 132 211 1.57E-9 T 10-11-2016 A4G23_RS13110 cdeae7631678173c6adebc9a6c9e8c66 225 SUPERFAMILY SSF160631 35 84 1.57E-9 T 10-11-2016 A4G23_RS13110 cdeae7631678173c6adebc9a6c9e8c66 225 SMART SM00860 38 207 7.2E-7 T 10-11-2016 IPR018958 SMI1/KNR4-like domain A4G23_RS21640 4beb96dff4edb1d09be350510879380b 390 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 238 383 8.0E-33 T 10-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4G23_RS21640 4beb96dff4edb1d09be350510879380b 390 Gene3D G3DSA:1.10.540.10 3 119 4.3E-22 T 10-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 A4G23_RS21640 4beb96dff4edb1d09be350510879380b 390 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 226 5.2E-21 T 10-11-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 A4G23_RS21640 4beb96dff4edb1d09be350510879380b 390 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 6.9E-21 T 10-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 A4G23_RS21640 4beb96dff4edb1d09be350510879380b 390 SUPERFAMILY SSF56645 3 248 6.15E-59 T 10-11-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 A4G23_RS21640 4beb96dff4edb1d09be350510879380b 390 Gene3D G3DSA:2.40.110.10 122 227 9.5E-30 T 10-11-2016 A4G23_RS21640 4beb96dff4edb1d09be350510879380b 390 SUPERFAMILY SSF47203 238 384 2.26E-34 T 10-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4G23_RS21640 4beb96dff4edb1d09be350510879380b 390 Gene3D G3DSA:1.20.140.10 228 384 3.6E-43 T 10-11-2016 A4G23_RS23170 78f25e8724af6e81e6c0192392743ad5 447 Gene3D G3DSA:3.40.50.300 8 220 1.4E-62 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS23170 78f25e8724af6e81e6c0192392743ad5 447 SUPERFAMILY SSF52540 15 220 7.47E-53 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS23170 78f25e8724af6e81e6c0192392743ad5 447 Gene3D G3DSA:2.40.30.10 322 423 8.6E-6 T 10-11-2016 A4G23_RS23170 78f25e8724af6e81e6c0192392743ad5 447 PRINTS PR00315 GTP-binding elongation factor signature 96 106 1.4E-11 T 10-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4G23_RS23170 78f25e8724af6e81e6c0192392743ad5 447 PRINTS PR00315 GTP-binding elongation factor signature 76 84 1.4E-11 T 10-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4G23_RS23170 78f25e8724af6e81e6c0192392743ad5 447 PRINTS PR00315 GTP-binding elongation factor signature 149 158 1.4E-11 T 10-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4G23_RS23170 78f25e8724af6e81e6c0192392743ad5 447 PRINTS PR00315 GTP-binding elongation factor signature 17 30 1.4E-11 T 10-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4G23_RS23170 78f25e8724af6e81e6c0192392743ad5 447 PRINTS PR00315 GTP-binding elongation factor signature 112 123 1.4E-11 T 10-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4G23_RS23170 78f25e8724af6e81e6c0192392743ad5 447 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 16 423 5.6E-165 T 10-11-2016 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 A4G23_RS23170 78f25e8724af6e81e6c0192392743ad5 447 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 69 84 - T 10-11-2016 IPR031157 Tr-type G domain, conserved site A4G23_RS23170 78f25e8724af6e81e6c0192392743ad5 447 Gene3D G3DSA:2.40.30.10 231 317 2.8E-13 T 10-11-2016 A4G23_RS23170 78f25e8724af6e81e6c0192392743ad5 447 Pfam PF00009 Elongation factor Tu GTP binding domain 16 199 2.5E-39 T 10-11-2016 A4G23_RS23170 78f25e8724af6e81e6c0192392743ad5 447 SUPERFAMILY SSF50447 229 320 1.84E-17 T 10-11-2016 IPR009000 Translation protein, beta-barrel domain A4G23_RS23170 78f25e8724af6e81e6c0192392743ad5 447 SUPERFAMILY SSF50465 323 423 2.88E-25 T 10-11-2016 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal A4G23_RS01645 2f4453e8179ac0f7cd0141dfab93866a 450 ProSitePatterns PS00659 Glycosyl hydrolases family 5 signature. 158 167 - T 10-11-2016 IPR018087 Glycoside hydrolase, family 5, conserved site GO:0004553|GO:0005975 A4G23_RS01645 2f4453e8179ac0f7cd0141dfab93866a 450 SUPERFAMILY SSF49384 344 448 3.28E-32 T 10-11-2016 IPR008965 Carbohydrate-binding domain GO:0030246 A4G23_RS01645 2f4453e8179ac0f7cd0141dfab93866a 450 Gene3D G3DSA:3.20.20.80 40 335 3.6E-76 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS01645 2f4453e8179ac0f7cd0141dfab93866a 450 ProSitePatterns PS00561 CBM2a (carbohydrate-binding type-2) domain signature. 412 425 - T 10-11-2016 IPR018366 Carbohydrate-binding type-2, conserved site GO:0004553|GO:0005975|GO:0030246 A4G23_RS01645 2f4453e8179ac0f7cd0141dfab93866a 450 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 48 294 1.2E-33 T 10-11-2016 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 A4G23_RS01645 2f4453e8179ac0f7cd0141dfab93866a 450 SMART SM00637 348 447 3.3E-44 T 10-11-2016 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 A4G23_RS01645 2f4453e8179ac0f7cd0141dfab93866a 450 Pfam PF00553 Cellulose binding domain 348 447 4.6E-29 T 10-11-2016 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 A4G23_RS01645 2f4453e8179ac0f7cd0141dfab93866a 450 Gene3D G3DSA:2.60.40.290 347 449 6.8E-36 T 10-11-2016 IPR012291 Cellulose-binding family II/chitobiase, carbohydrate-binding domain GO:0004553|GO:0030247 A4G23_RS01645 2f4453e8179ac0f7cd0141dfab93866a 450 SUPERFAMILY SSF51445 39 333 1.18E-75 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS00680 c71056e8b8fee4103ee9e9d77bd728ef 743 Gene3D G3DSA:2.130.10.140 475 737 1.3E-36 T 10-11-2016 A4G23_RS00680 c71056e8b8fee4103ee9e9d77bd728ef 743 Gene3D G3DSA:2.130.10.140 67 459 6.3E-71 T 10-11-2016 A4G23_RS00680 c71056e8b8fee4103ee9e9d77bd728ef 743 Pfam PF02012 BNR/Asp-box repeat 507 516 0.059 T 10-11-2016 IPR002860 BNR repeat A4G23_RS00680 c71056e8b8fee4103ee9e9d77bd728ef 743 SUPERFAMILY SSF110296 57 424 1.1E-64 T 10-11-2016 A4G23_RS00680 c71056e8b8fee4103ee9e9d77bd728ef 743 SUPERFAMILY SSF110296 423 741 1.12E-40 T 10-11-2016 A4G23_RS16970 cd22a48d77795e75298528e1d5f6b710 501 Gene3D G3DSA:3.20.20.70 12 498 1.4E-193 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS16970 cd22a48d77795e75298528e1d5f6b710 501 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 16 499 82.457 T 10-11-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 A4G23_RS16970 cd22a48d77795e75298528e1d5f6b710 501 SUPERFAMILY SSF54631 76 211 7.71E-30 T 10-11-2016 A4G23_RS16970 cd22a48d77795e75298528e1d5f6b710 501 SMART SM01240 15 486 0.0 T 10-11-2016 A4G23_RS16970 cd22a48d77795e75298528e1d5f6b710 501 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 301 313 - T 10-11-2016 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 A4G23_RS16970 cd22a48d77795e75298528e1d5f6b710 501 Pfam PF00571 CBS domain 157 212 8.2E-6 T 10-11-2016 IPR000644 CBS domain A4G23_RS16970 cd22a48d77795e75298528e1d5f6b710 501 Pfam PF00571 CBS domain 101 148 5.2E-8 T 10-11-2016 IPR000644 CBS domain A4G23_RS16970 cd22a48d77795e75298528e1d5f6b710 501 PIRSF PIRSF000130 7 501 1.3E-200 T 10-11-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 A4G23_RS16970 cd22a48d77795e75298528e1d5f6b710 501 SUPERFAMILY SSF51412 11 98 6.54E-119 T 10-11-2016 A4G23_RS16970 cd22a48d77795e75298528e1d5f6b710 501 SUPERFAMILY SSF51412 224 490 6.54E-119 T 10-11-2016 A4G23_RS16970 cd22a48d77795e75298528e1d5f6b710 501 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 16 467 3.9E-181 T 10-11-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 A4G23_RS16970 cd22a48d77795e75298528e1d5f6b710 501 SMART SM00116 165 213 9.2E-6 T 10-11-2016 IPR000644 CBS domain A4G23_RS16970 cd22a48d77795e75298528e1d5f6b710 501 SMART SM00116 104 152 1.3E-8 T 10-11-2016 IPR000644 CBS domain A4G23_RS16970 cd22a48d77795e75298528e1d5f6b710 501 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 16 486 1.3E-156 T 10-11-2016 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 A4G23_RS14735 ad841512064910dfc178f1e0ee6fc882 423 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 64 407 3.5E-116 T 10-11-2016 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A4G23_RS14735 ad841512064910dfc178f1e0ee6fc882 423 SUPERFAMILY SSF55021 334 409 2.98E-21 T 10-11-2016 A4G23_RS14735 ad841512064910dfc178f1e0ee6fc882 423 SUPERFAMILY SSF55021 252 330 1.43E-18 T 10-11-2016 A4G23_RS14735 ad841512064910dfc178f1e0ee6fc882 423 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 10-11-2016 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A4G23_RS14735 ad841512064910dfc178f1e0ee6fc882 423 Pfam PF13840 ACT domain 342 403 6.5E-13 T 10-11-2016 IPR027795 GATS-like ACT domain A4G23_RS14735 ad841512064910dfc178f1e0ee6fc882 423 Gene3D G3DSA:3.40.1160.10 3 244 1.7E-71 T 10-11-2016 IPR001048 Aspartate/glutamate/uridylate kinase A4G23_RS14735 ad841512064910dfc178f1e0ee6fc882 423 Pfam PF01842 ACT domain 270 329 2.9E-9 T 10-11-2016 IPR002912 ACT domain GO:0008152|GO:0016597 A4G23_RS14735 ad841512064910dfc178f1e0ee6fc882 423 PIRSF PIRSF000726 59 415 3.7E-127 T 10-11-2016 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A4G23_RS14735 ad841512064910dfc178f1e0ee6fc882 423 Pfam PF00696 Amino acid kinase family 3 231 9.3E-56 T 10-11-2016 IPR001048 Aspartate/glutamate/uridylate kinase A4G23_RS14735 ad841512064910dfc178f1e0ee6fc882 423 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 2 407 1.2E-126 T 10-11-2016 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A4G23_RS14735 ad841512064910dfc178f1e0ee6fc882 423 Gene3D G3DSA:3.30.70.260 266 337 2.6E-4 T 10-11-2016 A4G23_RS14735 ad841512064910dfc178f1e0ee6fc882 423 SUPERFAMILY SSF53633 4 244 3.67E-72 T 10-11-2016 IPR001048 Aspartate/glutamate/uridylate kinase A4G23_RS21210 3b3a41294d2587f3b5e4de8b64a70853 245 SMART SM00448 1 117 2.2E-37 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS21210 3b3a41294d2587f3b5e4de8b64a70853 245 SMART SM00862 164 236 1.7E-24 T 10-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4G23_RS21210 3b3a41294d2587f3b5e4de8b64a70853 245 SUPERFAMILY SSF52172 1 198 7.26E-36 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS21210 3b3a41294d2587f3b5e4de8b64a70853 245 Gene3D G3DSA:3.40.50.2300 1 125 2.0E-35 T 10-11-2016 A4G23_RS21210 3b3a41294d2587f3b5e4de8b64a70853 245 Pfam PF00486 Transcriptional regulatory protein, C terminal 165 236 6.2E-25 T 10-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4G23_RS21210 3b3a41294d2587f3b5e4de8b64a70853 245 Pfam PF00072 Response regulator receiver domain 4 117 3.3E-24 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS21210 3b3a41294d2587f3b5e4de8b64a70853 245 Gene3D G3DSA:1.10.10.10 145 239 8.2E-31 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS10310 46d1e91905eccb7c89549adf26035e0f 406 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 403 9.8E-140 T 10-11-2016 IPR002155 Thiolase GO:0008152|GO:0016747 A4G23_RS10310 46d1e91905eccb7c89549adf26035e0f 406 PIRSF PIRSF000429 1 406 1.2E-127 T 10-11-2016 IPR002155 Thiolase GO:0008152|GO:0016747 A4G23_RS10310 46d1e91905eccb7c89549adf26035e0f 406 Gene3D G3DSA:3.40.47.10 210 288 5.0E-61 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS10310 46d1e91905eccb7c89549adf26035e0f 406 Gene3D G3DSA:3.40.47.10 4 125 5.0E-61 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS10310 46d1e91905eccb7c89549adf26035e0f 406 SUPERFAMILY SSF53901 3 282 3.26E-67 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS10310 46d1e91905eccb7c89549adf26035e0f 406 SUPERFAMILY SSF53901 283 404 4.57E-43 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS10310 46d1e91905eccb7c89549adf26035e0f 406 Gene3D G3DSA:3.40.47.10 170 209 1.6E-56 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS10310 46d1e91905eccb7c89549adf26035e0f 406 Gene3D G3DSA:3.40.47.10 289 404 1.6E-56 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS10310 46d1e91905eccb7c89549adf26035e0f 406 ProSitePatterns PS00737 Thiolases signature 2. 351 367 - T 10-11-2016 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 A4G23_RS10310 46d1e91905eccb7c89549adf26035e0f 406 Pfam PF02803 Thiolase, C-terminal domain 282 404 1.8E-47 T 10-11-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 A4G23_RS10310 46d1e91905eccb7c89549adf26035e0f 406 Pfam PF00108 Thiolase, N-terminal domain 5 274 1.7E-61 T 10-11-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 A4G23_RS14310 b778691c3f8740bef55ca31d6e725817 437 Pfam PF00571 CBS domain 223 273 5.1E-5 T 10-11-2016 IPR000644 CBS domain A4G23_RS14310 b778691c3f8740bef55ca31d6e725817 437 Pfam PF00571 CBS domain 289 338 2.3E-6 T 10-11-2016 IPR000644 CBS domain A4G23_RS14310 b778691c3f8740bef55ca31d6e725817 437 Pfam PF01595 Domain of unknown function DUF21 10 202 3.7E-34 T 10-11-2016 IPR002550 Domain of unknown function DUF21 A4G23_RS14310 b778691c3f8740bef55ca31d6e725817 437 Pfam PF03471 Transporter associated domain 355 429 3.5E-22 T 10-11-2016 IPR005170 Transporter-associated domain A4G23_RS14310 b778691c3f8740bef55ca31d6e725817 437 Gene3D G3DSA:3.30.465.10 333 429 6.6E-24 T 10-11-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 A4G23_RS14310 b778691c3f8740bef55ca31d6e725817 437 Gene3D G3DSA:3.10.580.10 208 332 4.8E-16 T 10-11-2016 A4G23_RS14310 b778691c3f8740bef55ca31d6e725817 437 SUPERFAMILY SSF56176 355 432 3.54E-19 T 10-11-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 A4G23_RS14310 b778691c3f8740bef55ca31d6e725817 437 SUPERFAMILY SSF54631 207 341 7.45E-28 T 10-11-2016 A4G23_RS14310 b778691c3f8740bef55ca31d6e725817 437 SMART SM00116 290 338 0.067 T 10-11-2016 IPR000644 CBS domain A4G23_RS14310 b778691c3f8740bef55ca31d6e725817 437 SMART SM00116 227 276 1.6 T 10-11-2016 IPR000644 CBS domain A4G23_RS14310 b778691c3f8740bef55ca31d6e725817 437 SMART SM01091 352 431 1.5E-22 T 10-11-2016 IPR005170 Transporter-associated domain A4G23_RS16780 80c43e292f2c30e3b90d890ee5c3a24b 315 Hamap MF_00215 Pantothenate kinase [coaA]. 1 315 170.405 T 10-11-2016 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 A4G23_RS16780 80c43e292f2c30e3b90d890ee5c3a24b 315 PIRSF PIRSF000545 1 315 1.8E-141 T 10-11-2016 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 A4G23_RS16780 80c43e292f2c30e3b90d890ee5c3a24b 315 Gene3D G3DSA:3.40.50.300 6 313 2.9E-104 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS16780 80c43e292f2c30e3b90d890ee5c3a24b 315 TIGRFAM TIGR00554 panK_bact: pantothenate kinase 6 314 2.5E-125 T 10-11-2016 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 A4G23_RS16780 80c43e292f2c30e3b90d890ee5c3a24b 315 SUPERFAMILY SSF52540 4 313 1.02E-70 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS16780 80c43e292f2c30e3b90d890ee5c3a24b 315 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 88 232 1.5E-10 T 10-11-2016 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 A4G23_RS12375 f1efe957fd7722e0fb1ca006a6e649ba 424 Pfam PF13530 Sterol carrier protein domain 193 421 2.1E-48 T 10-11-2016 IPR025559 Enhanced intracellular survival protein domain A4G23_RS12375 f1efe957fd7722e0fb1ca006a6e649ba 424 Pfam PF13527 Acetyltransferase (GNAT) domain 15 141 2.3E-29 T 10-11-2016 A4G23_RS12375 f1efe957fd7722e0fb1ca006a6e649ba 424 Gene3D G3DSA:3.40.630.30 139 315 9.9E-32 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS12375 f1efe957fd7722e0fb1ca006a6e649ba 424 SUPERFAMILY SSF55718 320 424 1.49E-18 T 10-11-2016 IPR003033 SCP2 sterol-binding domain A4G23_RS12375 f1efe957fd7722e0fb1ca006a6e649ba 424 Hamap MF_01812 UPF0256 protein . 7 424 45.303 T 10-11-2016 IPR022902 Uncharacterised protein family UPF0256 A4G23_RS12375 f1efe957fd7722e0fb1ca006a6e649ba 424 Gene3D G3DSA:3.40.630.30 14 138 2.5E-23 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS12375 f1efe957fd7722e0fb1ca006a6e649ba 424 Gene3D G3DSA:3.30.1050.10 321 411 7.3E-16 T 10-11-2016 IPR003033 SCP2 sterol-binding domain A4G23_RS12375 f1efe957fd7722e0fb1ca006a6e649ba 424 SUPERFAMILY SSF55729 15 319 1.48E-57 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS06515 980dbc09fa76b7b53496304d3a94193b 239 SUPERFAMILY SSF144091 15 226 1.07E-36 T 10-11-2016 A4G23_RS06515 980dbc09fa76b7b53496304d3a94193b 239 Gene3D G3DSA:1.20.1540.10 15 219 3.4E-36 T 10-11-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 A4G23_RS06515 980dbc09fa76b7b53496304d3a94193b 239 Pfam PF01694 Rhomboid family 76 222 1.9E-36 T 10-11-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 A4G23_RS02740 eba002ab95a9daf0b3a883e01b6ff1c3 392 Gene3D G3DSA:1.10.630.10 9 391 4.4E-87 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS02740 eba002ab95a9daf0b3a883e01b6ff1c3 392 PRINTS PR00385 P450 superfamily signature 341 352 1.4E-5 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS02740 eba002ab95a9daf0b3a883e01b6ff1c3 392 PRINTS PR00385 P450 superfamily signature 267 278 1.4E-5 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS02740 eba002ab95a9daf0b3a883e01b6ff1c3 392 PRINTS PR00385 P450 superfamily signature 234 251 1.4E-5 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS02740 eba002ab95a9daf0b3a883e01b6ff1c3 392 PRINTS PR00385 P450 superfamily signature 332 341 1.4E-5 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS02740 eba002ab95a9daf0b3a883e01b6ff1c3 392 PRINTS PR00359 B-class P450 signature 267 278 2.7E-27 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS02740 eba002ab95a9daf0b3a883e01b6ff1c3 392 PRINTS PR00359 B-class P450 signature 341 352 2.7E-27 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS02740 eba002ab95a9daf0b3a883e01b6ff1c3 392 PRINTS PR00359 B-class P450 signature 135 151 2.7E-27 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS02740 eba002ab95a9daf0b3a883e01b6ff1c3 392 PRINTS PR00359 B-class P450 signature 285 312 2.7E-27 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS02740 eba002ab95a9daf0b3a883e01b6ff1c3 392 PRINTS PR00359 B-class P450 signature 152 167 2.7E-27 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS02740 eba002ab95a9daf0b3a883e01b6ff1c3 392 PRINTS PR00359 B-class P450 signature 84 95 2.7E-27 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS02740 eba002ab95a9daf0b3a883e01b6ff1c3 392 PRINTS PR00359 B-class P450 signature 332 341 2.7E-27 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS02740 eba002ab95a9daf0b3a883e01b6ff1c3 392 SUPERFAMILY SSF48264 18 389 1.7E-66 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS02740 eba002ab95a9daf0b3a883e01b6ff1c3 392 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 334 343 - T 10-11-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A4G23_RS02740 eba002ab95a9daf0b3a883e01b6ff1c3 392 Pfam PF00067 Cytochrome P450 268 362 3.0E-15 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS11360 1df1e74feda8ec179941e8716fe3031f 960 Gene3D G3DSA:3.40.50.300 293 388 8.1E-6 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS11360 1df1e74feda8ec179941e8716fe3031f 960 SUPERFAMILY SSF48452 91 261 2.01E-34 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS11360 1df1e74feda8ec179941e8716fe3031f 960 SUPERFAMILY SSF52540 263 523 1.4E-29 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS11360 1df1e74feda8ec179941e8716fe3031f 960 SUPERFAMILY SSF48452 785 928 6.75E-16 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS11360 1df1e74feda8ec179941e8716fe3031f 960 SMART SM00862 15 87 6.3E-10 T 10-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4G23_RS11360 1df1e74feda8ec179941e8716fe3031f 960 SUPERFAMILY SSF46894 3 86 2.72E-12 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS11360 1df1e74feda8ec179941e8716fe3031f 960 Pfam PF13424 Tetratricopeptide repeat 752 821 2.3E-9 T 10-11-2016 A4G23_RS11360 1df1e74feda8ec179941e8716fe3031f 960 Pfam PF13424 Tetratricopeptide repeat 829 899 9.6E-9 T 10-11-2016 A4G23_RS11360 1df1e74feda8ec179941e8716fe3031f 960 Pfam PF00486 Transcriptional regulatory protein, C terminal 22 76 2.4E-7 T 10-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4G23_RS11360 1df1e74feda8ec179941e8716fe3031f 960 PRINTS PR00364 Disease resistance protein signature 457 471 2.7E-9 T 10-11-2016 A4G23_RS11360 1df1e74feda8ec179941e8716fe3031f 960 PRINTS PR00364 Disease resistance protein signature 295 310 2.7E-9 T 10-11-2016 A4G23_RS11360 1df1e74feda8ec179941e8716fe3031f 960 PRINTS PR00364 Disease resistance protein signature 372 386 2.7E-9 T 10-11-2016 A4G23_RS11360 1df1e74feda8ec179941e8716fe3031f 960 SUPERFAMILY SSF48452 709 823 4.38E-11 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS11360 1df1e74feda8ec179941e8716fe3031f 960 Pfam PF03704 Bacterial transcriptional activator domain 94 238 1.0E-44 T 10-11-2016 IPR005158 Bacterial transcriptional activator domain A4G23_RS11360 1df1e74feda8ec179941e8716fe3031f 960 Gene3D G3DSA:1.25.40.10 707 861 7.9E-20 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS11360 1df1e74feda8ec179941e8716fe3031f 960 Gene3D G3DSA:1.10.10.10 22 88 9.7E-7 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS11360 1df1e74feda8ec179941e8716fe3031f 960 Pfam PF00931 NB-ARC domain 278 477 4.3E-14 T 10-11-2016 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6803207 A4G23_RS11360 1df1e74feda8ec179941e8716fe3031f 960 SMART SM01043 94 238 6.6E-53 T 10-11-2016 IPR005158 Bacterial transcriptional activator domain A4G23_RS11360 1df1e74feda8ec179941e8716fe3031f 960 SMART SM00028 830 863 1.5 T 10-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 A4G23_RS11360 1df1e74feda8ec179941e8716fe3031f 960 SMART SM00028 790 823 130.0 T 10-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 A4G23_RS11360 1df1e74feda8ec179941e8716fe3031f 960 SMART SM00028 909 942 13.0 T 10-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 A4G23_RS02025 ebfe79445ac32f91c9acea13f7bc066a 337 SUPERFAMILY SSF51004 17 326 3.66E-44 T 10-11-2016 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain A4G23_RS02025 ebfe79445ac32f91c9acea13f7bc066a 337 Pfam PF10282 Lactonase, 7-bladed beta-propeller 1 335 1.8E-95 T 10-11-2016 IPR019405 Lactonase, 7-bladed beta propeller KEGG: 00030+3.1.1.31 A4G23_RS02025 ebfe79445ac32f91c9acea13f7bc066a 337 Gene3D G3DSA:2.130.10.10 1 336 3.7E-89 T 10-11-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 A4G23_RS03960 e0dd77df7442a2a21edd98648c909303 223 SMART SM00563 35 154 1.2E-33 T 10-11-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 A4G23_RS03960 e0dd77df7442a2a21edd98648c909303 223 Pfam PF01553 Acyltransferase 21 150 9.6E-24 T 10-11-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 A4G23_RS03960 e0dd77df7442a2a21edd98648c909303 223 Gene3D G3DSA:3.40.1130.10 8 207 1.5E-35 T 10-11-2016 A4G23_RS03960 e0dd77df7442a2a21edd98648c909303 223 SUPERFAMILY SSF69593 6 221 1.24E-50 T 10-11-2016 A4G23_RS22135 7abb2e5a8d8bed42a0201b7c07049bc8 275 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS22135 7abb2e5a8d8bed42a0201b7c07049bc8 275 Pfam PF00005 ABC transporter 22 170 1.6E-31 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS22135 7abb2e5a8d8bed42a0201b7c07049bc8 275 Gene3D G3DSA:3.40.50.300 4 229 4.1E-63 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS22135 7abb2e5a8d8bed42a0201b7c07049bc8 275 SUPERFAMILY SSF52540 6 227 2.87E-62 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS22135 7abb2e5a8d8bed42a0201b7c07049bc8 275 SMART SM00382 30 214 5.0E-18 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS26800 e22fcb0ad28ba45f540475c94d2b54d6 1133 Pfam PF00550 Phosphopantetheine attachment site 614 679 1.0E-11 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS26800 e22fcb0ad28ba45f540475c94d2b54d6 1133 Gene3D G3DSA:3.40.50.980 212 379 2.2E-22 T 10-11-2016 A4G23_RS26800 e22fcb0ad28ba45f540475c94d2b54d6 1133 SUPERFAMILY SSF51735 732 1049 8.26E-34 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS26800 e22fcb0ad28ba45f540475c94d2b54d6 1133 Pfam PF07993 Male sterility protein 736 994 6.2E-52 T 10-11-2016 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 A4G23_RS26800 e22fcb0ad28ba45f540475c94d2b54d6 1133 TIGRFAM TIGR01746 Thioester-redct: thioester reductase domain 733 1121 6.1E-84 T 10-11-2016 IPR010080 Thioester reductase-like domain A4G23_RS26800 e22fcb0ad28ba45f540475c94d2b54d6 1133 SMART SM00823 Phosphopantetheine attachment site 611 683 2.2E-8 T 10-11-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4G23_RS26800 e22fcb0ad28ba45f540475c94d2b54d6 1133 Gene3D G3DSA:1.10.1200.10 609 683 2.1E-13 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS26800 e22fcb0ad28ba45f540475c94d2b54d6 1133 Gene3D G3DSA:2.30.38.10 404 461 2.3E-12 T 10-11-2016 A4G23_RS26800 e22fcb0ad28ba45f540475c94d2b54d6 1133 Pfam PF00501 AMP-binding enzyme 28 469 6.9E-66 T 10-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A4G23_RS26800 e22fcb0ad28ba45f540475c94d2b54d6 1133 Gene3D G3DSA:3.40.50.720 733 1016 4.5E-29 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS26800 e22fcb0ad28ba45f540475c94d2b54d6 1133 SUPERFAMILY SSF47336 609 694 2.22E-14 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS26800 e22fcb0ad28ba45f540475c94d2b54d6 1133 ProSitePatterns PS00455 Putative AMP-binding domain signature. 205 216 - T 10-11-2016 IPR020845 AMP-binding, conserved site A4G23_RS26800 e22fcb0ad28ba45f540475c94d2b54d6 1133 SUPERFAMILY SSF56801 36 597 1.44E-84 T 10-11-2016 A4G23_RS26800 e22fcb0ad28ba45f540475c94d2b54d6 1133 Gene3D G3DSA:3.40.50.980 190 211 1.3E-23 T 10-11-2016 A4G23_RS26800 e22fcb0ad28ba45f540475c94d2b54d6 1133 Gene3D G3DSA:3.40.50.980 18 150 1.3E-23 T 10-11-2016 A4G23_RS20335 b0609cc1a5d689f222ec1fc639403d9f 223 SMART SM00411 1 89 6.3E-38 T 10-11-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 A4G23_RS20335 b0609cc1a5d689f222ec1fc639403d9f 223 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 45 64 - T 10-11-2016 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 A4G23_RS20335 b0609cc1a5d689f222ec1fc639403d9f 223 SUPERFAMILY SSF47729 1 92 1.13E-24 T 10-11-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 A4G23_RS20335 b0609cc1a5d689f222ec1fc639403d9f 223 Pfam PF00216 Bacterial DNA-binding protein 1 88 1.3E-23 T 10-11-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 A4G23_RS20335 b0609cc1a5d689f222ec1fc639403d9f 223 Gene3D G3DSA:4.10.520.10 1 89 2.8E-27 T 10-11-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 A4G23_RS20335 b0609cc1a5d689f222ec1fc639403d9f 223 PRINTS PR01727 Prokaryotic integration host factor signature 39 54 2.7E-13 T 10-11-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 A4G23_RS20335 b0609cc1a5d689f222ec1fc639403d9f 223 PRINTS PR01727 Prokaryotic integration host factor signature 73 87 2.7E-13 T 10-11-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 A4G23_RS20335 b0609cc1a5d689f222ec1fc639403d9f 223 PRINTS PR01727 Prokaryotic integration host factor signature 57 70 2.7E-13 T 10-11-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 A4G23_RS00890 49824f830d544be86005df8de74632b5 230 TIGRFAM TIGR00123 cbiM: cobalamin biosynthesis protein CbiM 1 205 5.0E-82 T 10-11-2016 IPR018024 Cobalamin (vitamin B12) biosynthesis protein CbiM GO:0006824|GO:0009236|GO:0016021|GO:0043190 A4G23_RS00890 49824f830d544be86005df8de74632b5 230 Hamap MF_01462 Cobalt transport protein CbiM [cbiM]. 1 216 27.998 T 10-11-2016 IPR018024 Cobalamin (vitamin B12) biosynthesis protein CbiM GO:0006824|GO:0009236|GO:0016021|GO:0043190 A4G23_RS00890 49824f830d544be86005df8de74632b5 230 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 2 207 3.6E-49 T 10-11-2016 IPR002751 Cobalamin (vitamin B12) biosynthesis CbiM family GO:0000041|GO:0016021 A4G23_RS00190 3f78cc899129056ee9cb4bcca6b823c8 346 SUPERFAMILY SSF53300 10 125 3.25E-10 T 10-11-2016 IPR002035 von Willebrand factor, type A A4G23_RS00190 3f78cc899129056ee9cb4bcca6b823c8 346 Gene3D G3DSA:3.40.50.410 11 125 8.3E-5 T 10-11-2016 IPR002035 von Willebrand factor, type A A4G23_RS24060 89823bbef30af0953d531be659dcf506 210 Gene3D G3DSA:3.60.15.10 1 177 4.1E-24 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS24060 89823bbef30af0953d531be659dcf506 210 SUPERFAMILY SSF56281 7 178 1.4E-17 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS24060 89823bbef30af0953d531be659dcf506 210 Pfam PF13483 Beta-lactamase superfamily domain 2 175 5.3E-20 T 10-11-2016 A4G23_RS19265 4969893fc803772d24192c849da2b823 371 SUPERFAMILY SSF55874 255 371 7.72E-12 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS19265 4969893fc803772d24192c849da2b823 371 Pfam PF07730 Histidine kinase 166 230 7.8E-13 T 10-11-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4G23_RS19265 4969893fc803772d24192c849da2b823 371 Gene3D G3DSA:3.30.565.10 276 371 2.9E-4 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS04075 531d95dd91c00253ec955b0e2620a2b3 67 SUPERFAMILY SSF50118 1 64 3.2E-25 T 10-11-2016 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor A4G23_RS04075 531d95dd91c00253ec955b0e2620a2b3 67 Pfam PF08940 Domain of unknown function (DUF1918) 1 58 6.7E-28 T 10-11-2016 IPR015035 Domain of unknown function DUF1918 A4G23_RS12260 0b2b97f97de1a729f6104e78fb0e4a0a 156 Gene3D G3DSA:3.40.630.30 55 156 4.0E-21 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS12260 0b2b97f97de1a729f6104e78fb0e4a0a 156 Pfam PF00583 Acetyltransferase (GNAT) family 56 123 1.0E-14 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS12260 0b2b97f97de1a729f6104e78fb0e4a0a 156 SUPERFAMILY SSF55729 3 133 1.5E-21 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS02005 8fdabbe008fe183a6f18e62db68ce8a0 361 SUPERFAMILY SSF110296 5 359 4.45E-55 T 10-11-2016 A4G23_RS02005 8fdabbe008fe183a6f18e62db68ce8a0 361 Gene3D G3DSA:2.130.10.10 6 359 5.6E-81 T 10-11-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 A4G23_RS23110 6fbe84cbf36e2e6c26a4e88346fa62e3 205 SUPERFAMILY SSF52833 6 165 2.01E-21 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS23110 6fbe84cbf36e2e6c26a4e88346fa62e3 205 Gene3D G3DSA:3.40.30.10 4 164 4.2E-13 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS23110 6fbe84cbf36e2e6c26a4e88346fa62e3 205 Pfam PF01323 DSBA-like thioredoxin domain 9 163 3.2E-10 T 10-11-2016 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 A4G23_RS19155 6b4bcf8d8e6946c294197dbea569af4b 407 Gene3D G3DSA:3.40.50.720 178 406 5.5E-68 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS19155 6b4bcf8d8e6946c294197dbea569af4b 407 SUPERFAMILY SSF51735 180 406 1.35E-66 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS19155 6b4bcf8d8e6946c294197dbea569af4b 407 PIRSF PIRSF000106 36 407 1.3E-71 T 10-11-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 A4G23_RS19155 6b4bcf8d8e6946c294197dbea569af4b 407 SMART SM00919 180 400 4.8E-106 T 10-11-2016 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 A4G23_RS19155 6b4bcf8d8e6946c294197dbea569af4b 407 Pfam PF00390 Malic enzyme, N-terminal domain 131 168 3.0E-6 T 10-11-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 A4G23_RS19155 6b4bcf8d8e6946c294197dbea569af4b 407 Pfam PF00390 Malic enzyme, N-terminal domain 37 130 3.2E-21 T 10-11-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 A4G23_RS19155 6b4bcf8d8e6946c294197dbea569af4b 407 Pfam PF03949 Malic enzyme, NAD binding domain 182 381 1.7E-18 T 10-11-2016 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 A4G23_RS19155 6b4bcf8d8e6946c294197dbea569af4b 407 SUPERFAMILY SSF53223 30 178 7.19E-56 T 10-11-2016 A4G23_RS19155 6b4bcf8d8e6946c294197dbea569af4b 407 SMART SM01274 35 168 3.0E-78 T 10-11-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 A4G23_RS19155 6b4bcf8d8e6946c294197dbea569af4b 407 Gene3D G3DSA:3.40.50.10380 33 177 1.1E-53 T 10-11-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 A4G23_RS13325 166033513119214b8a2074c5f29a320a 290 Pfam PF12401 Protein of unknown function (DUF2662) 4 118 6.9E-42 T 10-11-2016 IPR022128 Protein of unknown function DUF3662 A4G23_RS13325 166033513119214b8a2074c5f29a320a 290 SUPERFAMILY SSF49879 181 286 2.49E-22 T 10-11-2016 IPR008984 SMAD/FHA domain GO:0005515 A4G23_RS13325 166033513119214b8a2074c5f29a320a 290 SMART SM00240 216 265 4.7E-12 T 10-11-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 A4G23_RS13325 166033513119214b8a2074c5f29a320a 290 Pfam PF16697 Inner membrane component of T3SS, cytoplasmic domain 206 287 1.9E-14 T 10-11-2016 IPR032030 YscD, cytoplasmic domain A4G23_RS13325 166033513119214b8a2074c5f29a320a 290 Gene3D G3DSA:2.60.200.20 206 286 4.1E-24 T 10-11-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 A4G23_RS20155 fc5a6a5c408d91158106cacdb64001c5 357 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 307 318 - T 10-11-2016 IPR033116 Serine proteases, trypsin family, serine active site A4G23_RS20155 fc5a6a5c408d91158106cacdb64001c5 357 PIRSF PIRSF001134 1 357 3.1E-115 T 10-11-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A4G23_RS20155 fc5a6a5c408d91158106cacdb64001c5 357 Gene3D G3DSA:3.30.300.50 99 165 4.7E-12 T 10-11-2016 A4G23_RS20155 fc5a6a5c408d91158106cacdb64001c5 357 Gene3D G3DSA:3.30.300.50 44 97 9.4E-10 T 10-11-2016 A4G23_RS20155 fc5a6a5c408d91158106cacdb64001c5 357 Gene3D G3DSA:2.40.10.10 171 254 2.9E-28 T 10-11-2016 A4G23_RS20155 fc5a6a5c408d91158106cacdb64001c5 357 Pfam PF00089 Trypsin 183 347 2.1E-6 T 10-11-2016 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 A4G23_RS20155 fc5a6a5c408d91158106cacdb64001c5 357 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 197 211 6.2E-42 T 10-11-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A4G23_RS20155 fc5a6a5c408d91158106cacdb64001c5 357 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 322 336 6.2E-42 T 10-11-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A4G23_RS20155 fc5a6a5c408d91158106cacdb64001c5 357 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 258 278 6.2E-42 T 10-11-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A4G23_RS20155 fc5a6a5c408d91158106cacdb64001c5 357 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 279 296 6.2E-42 T 10-11-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A4G23_RS20155 fc5a6a5c408d91158106cacdb64001c5 357 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 298 321 6.2E-42 T 10-11-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A4G23_RS20155 fc5a6a5c408d91158106cacdb64001c5 357 SUPERFAMILY SSF50494 173 352 6.56E-37 T 10-11-2016 IPR009003 Peptidase S1, PA clan A4G23_RS20155 fc5a6a5c408d91158106cacdb64001c5 357 Gene3D G3DSA:2.40.10.10 255 353 4.5E-22 T 10-11-2016 A4G23_RS20155 fc5a6a5c408d91158106cacdb64001c5 357 Pfam PF02983 Alpha-lytic protease prodomain 99 153 3.6E-14 T 10-11-2016 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 A4G23_RS20155 fc5a6a5c408d91158106cacdb64001c5 357 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 199 204 - T 10-11-2016 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 A4G23_RS05450 92d7129ed04c7858460e776c50f9286f 302 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 293 1.7E-17 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS05450 92d7129ed04c7858460e776c50f9286f 302 Gene3D G3DSA:1.10.3720.10 32 289 2.1E-63 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS05450 92d7129ed04c7858460e776c50f9286f 302 SUPERFAMILY SSF161098 38 302 1.4E-67 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS27115 b490a4f9a579e97520e9a05298d3d40f 244 Pfam PF00196 Bacterial regulatory proteins, luxR family 167 221 2.3E-16 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS27115 b490a4f9a579e97520e9a05298d3d40f 244 Gene3D G3DSA:1.10.10.10 167 223 2.7E-25 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS27115 b490a4f9a579e97520e9a05298d3d40f 244 SMART SM00448 14 127 2.7E-25 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS27115 b490a4f9a579e97520e9a05298d3d40f 244 ProSitePatterns PS00622 LuxR-type HTH domain signature. 181 208 - T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS27115 b490a4f9a579e97520e9a05298d3d40f 244 Gene3D G3DSA:3.40.50.2300 12 166 1.1E-36 T 10-11-2016 A4G23_RS27115 b490a4f9a579e97520e9a05298d3d40f 244 Pfam PF00072 Response regulator receiver domain 16 128 4.4E-24 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS27115 b490a4f9a579e97520e9a05298d3d40f 244 SUPERFAMILY SSF52172 13 140 2.85E-29 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS27115 b490a4f9a579e97520e9a05298d3d40f 244 SUPERFAMILY SSF46894 156 223 3.74E-19 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS27115 b490a4f9a579e97520e9a05298d3d40f 244 SMART SM00421 164 221 2.4E-23 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS27115 b490a4f9a579e97520e9a05298d3d40f 244 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 197 5.9E-13 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS27115 b490a4f9a579e97520e9a05298d3d40f 244 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 197 209 5.9E-13 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS27115 b490a4f9a579e97520e9a05298d3d40f 244 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 181 5.9E-13 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS02575 5343fe4a58fff185566223d34e8bf9d4 423 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 232 321 5.3E-14 T 10-11-2016 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 A4G23_RS02575 5343fe4a58fff185566223d34e8bf9d4 423 Pfam PF04055 Radical SAM superfamily 65 220 3.2E-14 T 10-11-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 A4G23_RS02575 5343fe4a58fff185566223d34e8bf9d4 423 SMART SM00876 232 322 8.2E-33 T 10-11-2016 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 A4G23_RS02575 5343fe4a58fff185566223d34e8bf9d4 423 SMART SM00729 55 261 1.9E-39 T 10-11-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 A4G23_RS02575 5343fe4a58fff185566223d34e8bf9d4 423 Hamap MF_01694 Biotin synthase [bioB]. 15 323 40.011 T 10-11-2016 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 A4G23_RS02575 5343fe4a58fff185566223d34e8bf9d4 423 TIGRFAM TIGR00433 bioB: biotin synthase 28 321 5.0E-113 T 10-11-2016 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 A4G23_RS02575 5343fe4a58fff185566223d34e8bf9d4 423 SUPERFAMILY SSF102114 18 321 3.53E-77 T 10-11-2016 A4G23_RS02575 5343fe4a58fff185566223d34e8bf9d4 423 Gene3D G3DSA:3.20.20.70 17 322 5.7E-89 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS11395 342f560cae0537fd3600970217a798ce 209 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 167 209 3.3E-10 T 10-11-2016 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 A4G23_RS11395 342f560cae0537fd3600970217a798ce 209 Gene3D G3DSA:2.30.110.10 12 209 4.0E-54 T 10-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 A4G23_RS11395 342f560cae0537fd3600970217a798ce 209 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 31 109 2.3E-17 T 10-11-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 A4G23_RS11395 342f560cae0537fd3600970217a798ce 209 SUPERFAMILY SSF50475 9 209 8.45E-45 T 10-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 A4G23_RS11395 342f560cae0537fd3600970217a798ce 209 PIRSF PIRSF000190 5 209 7.5E-51 T 10-11-2016 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 A4G23_RS07515 2920bac794b183fb99346c37a584379d 164 Pfam PF11343 Protein of unknown function (DUF3145) 6 162 6.5E-73 T 10-11-2016 IPR021491 Protein of unknown function DUF3145 A4G23_RS15115 159e31fad05c7e08574dee06fd988ada 445 Gene3D G3DSA:3.40.50.720 4 49 1.2E-13 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS15115 159e31fad05c7e08574dee06fd988ada 445 Gene3D G3DSA:3.40.50.720 86 185 1.2E-13 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS15115 159e31fad05c7e08574dee06fd988ada 445 Gene3D G3DSA:3.50.50.60 186 220 2.6E-12 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS15115 159e31fad05c7e08574dee06fd988ada 445 Gene3D G3DSA:3.50.50.60 256 404 2.6E-12 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS15115 159e31fad05c7e08574dee06fd988ada 445 SUPERFAMILY SSF51905 258 403 2.96E-23 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS15115 159e31fad05c7e08574dee06fd988ada 445 SUPERFAMILY SSF51905 2 205 2.96E-23 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS15115 159e31fad05c7e08574dee06fd988ada 445 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 5 27 7.5E-14 T 10-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4G23_RS15115 159e31fad05c7e08574dee06fd988ada 445 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 170 194 7.5E-14 T 10-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4G23_RS15115 159e31fad05c7e08574dee06fd988ada 445 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 7 205 1.1E-12 T 10-11-2016 A4G23_RS15115 159e31fad05c7e08574dee06fd988ada 445 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 319 335 2.4E-8 T 10-11-2016 A4G23_RS15115 159e31fad05c7e08574dee06fd988ada 445 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 353 375 2.4E-8 T 10-11-2016 A4G23_RS15115 159e31fad05c7e08574dee06fd988ada 445 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 2.4E-8 T 10-11-2016 A4G23_RS25830 98f7de8a14588b9db068ca2f899ed5b0 296 Gene3D G3DSA:1.10.10.10 1 85 1.9E-31 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS25830 98f7de8a14588b9db068ca2f899ed5b0 296 Gene3D G3DSA:3.40.190.10 178 266 4.9E-24 T 10-11-2016 A4G23_RS25830 98f7de8a14588b9db068ca2f899ed5b0 296 SUPERFAMILY SSF46785 1 110 6.99E-27 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS25830 98f7de8a14588b9db068ca2f899ed5b0 296 SUPERFAMILY SSF53850 90 291 2.63E-40 T 10-11-2016 A4G23_RS25830 98f7de8a14588b9db068ca2f899ed5b0 296 Pfam PF03466 LysR substrate binding domain 88 290 1.6E-44 T 10-11-2016 IPR005119 LysR, substrate-binding A4G23_RS25830 98f7de8a14588b9db068ca2f899ed5b0 296 Gene3D G3DSA:3.40.190.10 90 177 3.0E-19 T 10-11-2016 A4G23_RS25830 98f7de8a14588b9db068ca2f899ed5b0 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 5.0E-24 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS25830 98f7de8a14588b9db068ca2f899ed5b0 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.6E-12 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS25830 98f7de8a14588b9db068ca2f899ed5b0 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.6E-12 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS25830 98f7de8a14588b9db068ca2f899ed5b0 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.6E-12 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS08950 5880fb21a5c7a1bf810a907be0ce9682 171 SUPERFAMILY SSF74853 20 110 3.4E-5 T 10-11-2016 IPR001322 Lamin Tail Domain A4G23_RS12435 b206f9bf18fb11b56f9155dc1106f32c 281 SUPERFAMILY SSF52821 151 278 6.16E-33 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS12435 b206f9bf18fb11b56f9155dc1106f32c 281 Gene3D G3DSA:3.40.250.10 152 278 2.0E-32 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS12435 b206f9bf18fb11b56f9155dc1106f32c 281 SMART SM00450 8 122 1.9E-19 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS12435 b206f9bf18fb11b56f9155dc1106f32c 281 SMART SM00450 146 273 2.8E-19 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS12435 b206f9bf18fb11b56f9155dc1106f32c 281 Pfam PF00581 Rhodanese-like domain 151 268 1.6E-15 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS12435 b206f9bf18fb11b56f9155dc1106f32c 281 Pfam PF00581 Rhodanese-like domain 10 118 3.4E-17 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS12435 b206f9bf18fb11b56f9155dc1106f32c 281 SUPERFAMILY SSF52821 4 130 7.2E-35 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS12435 b206f9bf18fb11b56f9155dc1106f32c 281 Gene3D G3DSA:3.40.250.10 4 132 2.8E-36 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS12435 b206f9bf18fb11b56f9155dc1106f32c 281 ProSitePatterns PS00683 Rhodanese C-terminal signature. 257 267 - T 10-11-2016 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 A4G23_RS27235 65413babb349d55465ee37557bb89d28 464 Gene3D G3DSA:3.30.499.10 327 463 8.0E-50 T 10-11-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 A4G23_RS27235 65413babb349d55465ee37557bb89d28 464 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 4 458 2.9E-179 T 10-11-2016 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 A4G23_RS27235 65413babb349d55465ee37557bb89d28 464 PRINTS PR00415 Aconitase family signature 83 96 9.3E-37 T 10-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4G23_RS27235 65413babb349d55465ee37557bb89d28 464 PRINTS PR00415 Aconitase family signature 109 117 9.3E-37 T 10-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4G23_RS27235 65413babb349d55465ee37557bb89d28 464 PRINTS PR00415 Aconitase family signature 210 223 9.3E-37 T 10-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4G23_RS27235 65413babb349d55465ee37557bb89d28 464 PRINTS PR00415 Aconitase family signature 284 298 9.3E-37 T 10-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4G23_RS27235 65413babb349d55465ee37557bb89d28 464 PRINTS PR00415 Aconitase family signature 398 411 9.3E-37 T 10-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4G23_RS27235 65413babb349d55465ee37557bb89d28 464 PRINTS PR00415 Aconitase family signature 341 352 9.3E-37 T 10-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4G23_RS27235 65413babb349d55465ee37557bb89d28 464 PRINTS PR00415 Aconitase family signature 196 209 9.3E-37 T 10-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4G23_RS27235 65413babb349d55465ee37557bb89d28 464 PRINTS PR00415 Aconitase family signature 120 133 9.3E-37 T 10-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4G23_RS27235 65413babb349d55465ee37557bb89d28 464 PRINTS PR00415 Aconitase family signature 134 149 9.3E-37 T 10-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4G23_RS27235 65413babb349d55465ee37557bb89d28 464 Pfam PF00330 Aconitase family (aconitate hydratase) 8 456 3.1E-131 T 10-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4G23_RS27235 65413babb349d55465ee37557bb89d28 464 ProSitePatterns PS00450 Aconitase family signature 1. 337 353 - T 10-11-2016 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 A4G23_RS27235 65413babb349d55465ee37557bb89d28 464 SUPERFAMILY SSF53732 3 462 2.09E-142 T 10-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4G23_RS27235 65413babb349d55465ee37557bb89d28 464 Gene3D G3DSA:3.40.1060.10 167 278 3.1E-33 T 10-11-2016 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 A4G23_RS27235 65413babb349d55465ee37557bb89d28 464 Gene3D G3DSA:3.30.499.10 8 164 7.8E-20 T 10-11-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 A4G23_RS18400 0a9a0d79efce82f77d23a3da79e86b7a 860 SUPERFAMILY SSF53850 53 287 1.32E-32 T 10-11-2016 A4G23_RS18400 0a9a0d79efce82f77d23a3da79e86b7a 860 Gene3D G3DSA:3.40.190.10 378 403 1.5E-22 T 10-11-2016 A4G23_RS18400 0a9a0d79efce82f77d23a3da79e86b7a 860 Gene3D G3DSA:3.40.190.10 221 292 1.5E-22 T 10-11-2016 A4G23_RS18400 0a9a0d79efce82f77d23a3da79e86b7a 860 SUPERFAMILY SSF53850 367 473 4.71E-13 T 10-11-2016 A4G23_RS18400 0a9a0d79efce82f77d23a3da79e86b7a 860 Gene3D G3DSA:3.90.76.10 66 220 3.7E-16 T 10-11-2016 A4G23_RS18400 0a9a0d79efce82f77d23a3da79e86b7a 860 Gene3D G3DSA:3.10.105.10 683 826 1.9E-62 T 10-11-2016 A4G23_RS18400 0a9a0d79efce82f77d23a3da79e86b7a 860 Gene3D G3DSA:3.10.105.10 404 468 1.9E-62 T 10-11-2016 A4G23_RS18400 0a9a0d79efce82f77d23a3da79e86b7a 860 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 115 286 7.7E-20 T 10-11-2016 IPR000914 Solute-binding protein family 5 domain A4G23_RS18400 0a9a0d79efce82f77d23a3da79e86b7a 860 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 641 755 3.6E-5 T 10-11-2016 IPR000914 Solute-binding protein family 5 domain A4G23_RS18400 0a9a0d79efce82f77d23a3da79e86b7a 860 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 348 473 4.6E-11 T 10-11-2016 IPR000914 Solute-binding protein family 5 domain A4G23_RS18400 0a9a0d79efce82f77d23a3da79e86b7a 860 SUPERFAMILY SSF53850 683 854 1.15E-23 T 10-11-2016 A4G23_RS01315 a45c62942e0f90f8d6d763e5b62aa4f0 400 Gene3D G3DSA:1.10.630.10 17 400 1.2E-106 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS01315 a45c62942e0f90f8d6d763e5b62aa4f0 400 PRINTS PR00359 B-class P450 signature 339 348 9.9E-44 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS01315 a45c62942e0f90f8d6d763e5b62aa4f0 400 PRINTS PR00359 B-class P450 signature 348 359 9.9E-44 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS01315 a45c62942e0f90f8d6d763e5b62aa4f0 400 PRINTS PR00359 B-class P450 signature 89 100 9.9E-44 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS01315 a45c62942e0f90f8d6d763e5b62aa4f0 400 PRINTS PR00359 B-class P450 signature 136 152 9.9E-44 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS01315 a45c62942e0f90f8d6d763e5b62aa4f0 400 PRINTS PR00359 B-class P450 signature 153 168 9.9E-44 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS01315 a45c62942e0f90f8d6d763e5b62aa4f0 400 PRINTS PR00359 B-class P450 signature 271 282 9.9E-44 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS01315 a45c62942e0f90f8d6d763e5b62aa4f0 400 PRINTS PR00359 B-class P450 signature 318 333 9.9E-44 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS01315 a45c62942e0f90f8d6d763e5b62aa4f0 400 PRINTS PR00359 B-class P450 signature 290 317 9.9E-44 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS01315 a45c62942e0f90f8d6d763e5b62aa4f0 400 Pfam PF00067 Cytochrome P450 248 368 1.2E-17 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS01315 a45c62942e0f90f8d6d763e5b62aa4f0 400 SUPERFAMILY SSF48264 3 400 9.82E-82 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS11490 faca7d324fdf4f4a87153ef0db664fae 230 SUPERFAMILY SSF46785 3 62 4.75E-13 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS11490 faca7d324fdf4f4a87153ef0db664fae 230 Gene3D G3DSA:1.10.60.10 75 133 7.0E-30 T 10-11-2016 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 A4G23_RS11490 faca7d324fdf4f4a87153ef0db664fae 230 SMART SM00529 26 125 9.7E-48 T 10-11-2016 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 A4G23_RS11490 faca7d324fdf4f4a87153ef0db664fae 230 Gene3D G3DSA:2.30.30.90 134 229 1.7E-32 T 10-11-2016 A4G23_RS11490 faca7d324fdf4f4a87153ef0db664fae 230 SUPERFAMILY SSF50037 130 229 2.2E-24 T 10-11-2016 IPR008988 Transcriptional repressor, C-terminal A4G23_RS11490 faca7d324fdf4f4a87153ef0db664fae 230 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 4 62 1.8E-19 T 10-11-2016 IPR022687 DTXR-type HTH domain GO:0003677 A4G23_RS11490 faca7d324fdf4f4a87153ef0db664fae 230 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 65 133 3.5E-29 T 10-11-2016 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 A4G23_RS11490 faca7d324fdf4f4a87153ef0db664fae 230 SMART SM00899 153 229 3.3E-6 T 10-11-2016 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 A4G23_RS11490 faca7d324fdf4f4a87153ef0db664fae 230 Gene3D G3DSA:1.10.10.10 2 73 3.0E-28 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS11490 faca7d324fdf4f4a87153ef0db664fae 230 SUPERFAMILY SSF47979 65 138 4.58E-26 T 10-11-2016 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 A4G23_RS11490 faca7d324fdf4f4a87153ef0db664fae 230 Pfam PF04023 FeoA domain 159 228 2.9E-7 T 10-11-2016 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 A4G23_RS07925 9192ae4b2f5afd58d77d8375d114ee0e 379 Gene3D G3DSA:2.60.260.20 104 137 9.3E-22 T 10-11-2016 A4G23_RS07925 9192ae4b2f5afd58d77d8375d114ee0e 379 Gene3D G3DSA:2.60.260.20 211 254 9.3E-22 T 10-11-2016 A4G23_RS07925 9192ae4b2f5afd58d77d8375d114ee0e 379 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 4 350 8.7E-120 T 10-11-2016 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 A4G23_RS07925 9192ae4b2f5afd58d77d8375d114ee0e 379 SUPERFAMILY SSF57938 131 211 2.62E-18 T 10-11-2016 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 A4G23_RS07925 9192ae4b2f5afd58d77d8375d114ee0e 379 Pfam PF00684 DnaJ central domain 144 208 1.6E-12 T 10-11-2016 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 A4G23_RS07925 9192ae4b2f5afd58d77d8375d114ee0e 379 SUPERFAMILY SSF49493 259 345 1.31E-20 T 10-11-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 A4G23_RS07925 9192ae4b2f5afd58d77d8375d114ee0e 379 Gene3D G3DSA:1.10.287.110 3 101 4.8E-33 T 10-11-2016 IPR001623 DnaJ domain A4G23_RS07925 9192ae4b2f5afd58d77d8375d114ee0e 379 PRINTS PR00625 DnaJ domain signature 24 39 3.1E-24 T 10-11-2016 IPR001623 DnaJ domain A4G23_RS07925 9192ae4b2f5afd58d77d8375d114ee0e 379 PRINTS PR00625 DnaJ domain signature 60 79 3.1E-24 T 10-11-2016 IPR001623 DnaJ domain A4G23_RS07925 9192ae4b2f5afd58d77d8375d114ee0e 379 PRINTS PR00625 DnaJ domain signature 6 24 3.1E-24 T 10-11-2016 IPR001623 DnaJ domain A4G23_RS07925 9192ae4b2f5afd58d77d8375d114ee0e 379 PRINTS PR00625 DnaJ domain signature 40 60 3.1E-24 T 10-11-2016 IPR001623 DnaJ domain A4G23_RS07925 9192ae4b2f5afd58d77d8375d114ee0e 379 Pfam PF00226 DnaJ domain 4 65 5.2E-26 T 10-11-2016 IPR001623 DnaJ domain A4G23_RS07925 9192ae4b2f5afd58d77d8375d114ee0e 379 Gene3D G3DSA:2.60.260.20 257 335 1.2E-20 T 10-11-2016 A4G23_RS07925 9192ae4b2f5afd58d77d8375d114ee0e 379 SMART SM00271 3 60 5.6E-31 T 10-11-2016 IPR001623 DnaJ domain A4G23_RS07925 9192ae4b2f5afd58d77d8375d114ee0e 379 SUPERFAMILY SSF46565 3 100 1.96E-32 T 10-11-2016 IPR001623 DnaJ domain A4G23_RS07925 9192ae4b2f5afd58d77d8375d114ee0e 379 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 1 375 38.042 T 10-11-2016 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 A4G23_RS07925 9192ae4b2f5afd58d77d8375d114ee0e 379 SUPERFAMILY SSF49493 214 258 4.19E-20 T 10-11-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 A4G23_RS07925 9192ae4b2f5afd58d77d8375d114ee0e 379 SUPERFAMILY SSF49493 116 149 4.19E-20 T 10-11-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 A4G23_RS07925 9192ae4b2f5afd58d77d8375d114ee0e 379 Pfam PF01556 DnaJ C terminal domain 119 334 5.3E-39 T 10-11-2016 IPR002939 Chaperone DnaJ, C-terminal A4G23_RS07925 9192ae4b2f5afd58d77d8375d114ee0e 379 Gene3D G3DSA:2.10.230.10 138 210 1.0E-19 T 10-11-2016 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 A4G23_RS07925 9192ae4b2f5afd58d77d8375d114ee0e 379 ProSitePatterns PS00636 Nt-dnaJ domain signature. 45 64 - T 10-11-2016 IPR018253 DnaJ domain, conserved site A4G23_RS20320 c429dd718c17581c0a98b69e45a27958 476 Gene3D G3DSA:3.40.1060.10 155 288 3.9E-41 T 10-11-2016 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 A4G23_RS20320 c429dd718c17581c0a98b69e45a27958 476 ProSitePatterns PS00450 Aconitase family signature 1. 339 355 - T 10-11-2016 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 A4G23_RS20320 c429dd718c17581c0a98b69e45a27958 476 SUPERFAMILY SSF53732 1 465 1.96E-164 T 10-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4G23_RS20320 c429dd718c17581c0a98b69e45a27958 476 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 1 466 59.628 T 10-11-2016 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 A4G23_RS20320 c429dd718c17581c0a98b69e45a27958 476 Gene3D G3DSA:3.30.499.10 330 466 5.1E-58 T 10-11-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 A4G23_RS20320 c429dd718c17581c0a98b69e45a27958 476 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 1 460 6.9E-228 T 10-11-2016 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 A4G23_RS20320 c429dd718c17581c0a98b69e45a27958 476 ProSitePatterns PS01244 Aconitase family signature 2. 399 412 - T 10-11-2016 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 A4G23_RS20320 c429dd718c17581c0a98b69e45a27958 476 PRINTS PR00415 Aconitase family signature 108 116 1.0E-46 T 10-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4G23_RS20320 c429dd718c17581c0a98b69e45a27958 476 PRINTS PR00415 Aconitase family signature 343 354 1.0E-46 T 10-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4G23_RS20320 c429dd718c17581c0a98b69e45a27958 476 PRINTS PR00415 Aconitase family signature 82 95 1.0E-46 T 10-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4G23_RS20320 c429dd718c17581c0a98b69e45a27958 476 PRINTS PR00415 Aconitase family signature 195 208 1.0E-46 T 10-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4G23_RS20320 c429dd718c17581c0a98b69e45a27958 476 PRINTS PR00415 Aconitase family signature 286 300 1.0E-46 T 10-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4G23_RS20320 c429dd718c17581c0a98b69e45a27958 476 PRINTS PR00415 Aconitase family signature 209 222 1.0E-46 T 10-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4G23_RS20320 c429dd718c17581c0a98b69e45a27958 476 PRINTS PR00415 Aconitase family signature 133 148 1.0E-46 T 10-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4G23_RS20320 c429dd718c17581c0a98b69e45a27958 476 PRINTS PR00415 Aconitase family signature 119 132 1.0E-46 T 10-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4G23_RS20320 c429dd718c17581c0a98b69e45a27958 476 PRINTS PR00415 Aconitase family signature 399 412 1.0E-46 T 10-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4G23_RS20320 c429dd718c17581c0a98b69e45a27958 476 Gene3D G3DSA:3.30.499.10 2 154 2.9E-22 T 10-11-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 A4G23_RS20320 c429dd718c17581c0a98b69e45a27958 476 Pfam PF00330 Aconitase family (aconitate hydratase) 7 457 3.2E-152 T 10-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A4G23_RS21985 c354919b63095f0bbb0605b421b7e7a7 289 SUPERFAMILY SSF47413 32 85 6.7E-9 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS21985 c354919b63095f0bbb0605b421b7e7a7 289 SMART SM00530 36 91 5.0E-8 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS21985 c354919b63095f0bbb0605b421b7e7a7 289 Gene3D G3DSA:1.10.260.40 33 84 5.7E-11 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS21985 c354919b63095f0bbb0605b421b7e7a7 289 Pfam PF13560 Helix-turn-helix domain 32 87 4.8E-15 T 10-11-2016 A4G23_RS16500 4e1e4f35492af8c73e4595e4aa32ed18 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 1.4E-59 T 10-11-2016 IPR023798 Ribosomal protein S7 domain A4G23_RS16500 4e1e4f35492af8c73e4595e4aa32ed18 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 2.4E-64 T 10-11-2016 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 A4G23_RS16500 4e1e4f35492af8c73e4595e4aa32ed18 156 SUPERFAMILY SSF47973 1 149 3.53E-57 T 10-11-2016 IPR023798 Ribosomal protein S7 domain A4G23_RS16500 4e1e4f35492af8c73e4595e4aa32ed18 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 34.679 T 10-11-2016 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 A4G23_RS16500 4e1e4f35492af8c73e4595e4aa32ed18 156 PIRSF PIRSF002122 7 156 1.7E-55 T 10-11-2016 IPR000235 Ribosomal protein S5/S7 GO:0006412 A4G23_RS16500 4e1e4f35492af8c73e4595e4aa32ed18 156 Gene3D G3DSA:1.10.455.10 8 156 2.8E-60 T 10-11-2016 IPR023798 Ribosomal protein S7 domain A4G23_RS16500 4e1e4f35492af8c73e4595e4aa32ed18 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 10-11-2016 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS05585 75e37333146801cae956359687a109f9 250 Pfam PF01022 Bacterial regulatory protein, arsR family 21 65 9.8E-7 T 10-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4G23_RS05585 75e37333146801cae956359687a109f9 250 SUPERFAMILY SSF46785 22 209 1.62E-29 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS05585 75e37333146801cae956359687a109f9 250 Gene3D G3DSA:1.10.10.10 24 120 3.2E-17 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS27175 2e51dd5b806242e0166c4ab132502cc2 78 Gene3D G3DSA:1.10.1200.10 2 73 9.9E-18 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS27175 2e51dd5b806242e0166c4ab132502cc2 78 Pfam PF00550 Phosphopantetheine attachment site 5 70 5.3E-12 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS27175 2e51dd5b806242e0166c4ab132502cc2 78 SUPERFAMILY SSF47336 3 73 4.84E-15 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS05620 3d9cb16785c191ceb744eab94696f761 372 TIGRFAM TIGR00876 tal_mycobact: transaldolase 12 358 7.3E-131 T 10-11-2016 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 A4G23_RS05620 3d9cb16785c191ceb744eab94696f761 372 Pfam PF00923 Transaldolase 15 359 2.8E-81 T 10-11-2016 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 A4G23_RS05620 3d9cb16785c191ceb744eab94696f761 372 Hamap MF_00493 Transaldolase [tal]. 1 370 160.302 T 10-11-2016 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 A4G23_RS05620 3d9cb16785c191ceb744eab94696f761 372 ProSitePatterns PS01054 Transaldolase signature 1. 41 49 - T 10-11-2016 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 A4G23_RS05620 3d9cb16785c191ceb744eab94696f761 372 SUPERFAMILY SSF51569 2 359 1.47E-74 T 10-11-2016 A4G23_RS05620 3d9cb16785c191ceb744eab94696f761 372 Gene3D G3DSA:3.20.20.70 1 359 2.0E-122 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS05620 3d9cb16785c191ceb744eab94696f761 372 PIRSF PIRSF036915 1 372 2.2E-175 T 10-11-2016 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 A4G23_RS07635 24d5b30960d1afc4b97ac4b809b90fa5 406 PRINTS PR00364 Disease resistance protein signature 168 182 4.6E-5 T 10-11-2016 A4G23_RS07635 24d5b30960d1afc4b97ac4b809b90fa5 406 PRINTS PR00364 Disease resistance protein signature 254 268 4.6E-5 T 10-11-2016 A4G23_RS07635 24d5b30960d1afc4b97ac4b809b90fa5 406 PRINTS PR00364 Disease resistance protein signature 87 102 4.6E-5 T 10-11-2016 A4G23_RS07635 24d5b30960d1afc4b97ac4b809b90fa5 406 Gene3D G3DSA:3.40.50.300 82 184 1.8E-11 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS07635 24d5b30960d1afc4b97ac4b809b90fa5 406 SMART SM00382 84 223 6.3E-9 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS07635 24d5b30960d1afc4b97ac4b809b90fa5 406 Pfam PF13245 Part of AAA domain 85 127 2.9E-7 T 10-11-2016 A4G23_RS07635 24d5b30960d1afc4b97ac4b809b90fa5 406 SUPERFAMILY SSF52540 64 268 6.0E-21 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS23510 ff10769ad54fa2a67151fe2a1d8ed2f5 163 SMART SM00347 42 143 1.4E-9 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS23510 ff10769ad54fa2a67151fe2a1d8ed2f5 163 Pfam PF12802 MarR family 48 106 6.9E-14 T 10-11-2016 A4G23_RS23510 ff10769ad54fa2a67151fe2a1d8ed2f5 163 Gene3D G3DSA:1.10.10.10 23 159 7.3E-29 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS23510 ff10769ad54fa2a67151fe2a1d8ed2f5 163 SUPERFAMILY SSF46785 20 157 2.73E-24 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS06325 bff4a22cd01c6e24a91b6c50f9f2b7bd 202 SUPERFAMILY SSF48498 88 191 1.14E-14 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS06325 bff4a22cd01c6e24a91b6c50f9f2b7bd 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 61 7.5E-20 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS06325 bff4a22cd01c6e24a91b6c50f9f2b7bd 202 Gene3D G3DSA:1.10.10.60 3 60 6.3E-23 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS06325 bff4a22cd01c6e24a91b6c50f9f2b7bd 202 SUPERFAMILY SSF46689 3 78 2.57E-21 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS06325 bff4a22cd01c6e24a91b6c50f9f2b7bd 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 6.4E-11 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS06325 bff4a22cd01c6e24a91b6c50f9f2b7bd 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 6.4E-11 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS06325 bff4a22cd01c6e24a91b6c50f9f2b7bd 202 Gene3D G3DSA:1.10.357.10 61 195 9.6E-29 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS08095 3c476f35e45778e7d9647b8f82cc91a8 433 Pfam PF00171 Aldehyde dehydrogenase family 19 298 2.4E-22 T 10-11-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A4G23_RS08095 3c476f35e45778e7d9647b8f82cc91a8 433 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 18 433 42.423 T 10-11-2016 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A4G23_RS08095 3c476f35e45778e7d9647b8f82cc91a8 433 Gene3D G3DSA:3.40.605.10 392 433 2.3E-104 T 10-11-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A4G23_RS08095 3c476f35e45778e7d9647b8f82cc91a8 433 Gene3D G3DSA:3.40.605.10 14 237 2.3E-104 T 10-11-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A4G23_RS08095 3c476f35e45778e7d9647b8f82cc91a8 433 PIRSF PIRSF000151 12 433 1.5E-175 T 10-11-2016 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 A4G23_RS08095 3c476f35e45778e7d9647b8f82cc91a8 433 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 340 361 - T 10-11-2016 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A4G23_RS08095 3c476f35e45778e7d9647b8f82cc91a8 433 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 26 423 3.1E-153 T 10-11-2016 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A4G23_RS08095 3c476f35e45778e7d9647b8f82cc91a8 433 SUPERFAMILY SSF53720 17 433 2.23E-118 T 10-11-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A4G23_RS08095 3c476f35e45778e7d9647b8f82cc91a8 433 Gene3D G3DSA:3.40.309.10 240 391 1.2E-42 T 10-11-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 A4G23_RS12245 7b80f36bfbbe7ef66c5a81177b09d0e6 401 Gene3D G3DSA:1.20.1250.20 223 399 6.1E-21 T 10-11-2016 A4G23_RS12245 7b80f36bfbbe7ef66c5a81177b09d0e6 401 Gene3D G3DSA:1.20.1250.20 22 200 6.1E-33 T 10-11-2016 A4G23_RS12245 7b80f36bfbbe7ef66c5a81177b09d0e6 401 ProSitePatterns PS00216 Sugar transport proteins signature 1. 74 90 - T 10-11-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A4G23_RS12245 7b80f36bfbbe7ef66c5a81177b09d0e6 401 Pfam PF07690 Major Facilitator Superfamily 24 282 3.0E-35 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS12245 7b80f36bfbbe7ef66c5a81177b09d0e6 401 SUPERFAMILY SSF103473 21 400 3.79E-63 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS24145 6a11ab7bf9c4ee134feaa4502709d0ad 84 SUPERFAMILY SSF47729 1 80 2.5E-6 T 10-11-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 A4G23_RS06400 bf3d82f3badb436462fb0018f25ffa29 451 Pfam PF01474 Class-II DAHP synthetase family 13 445 1.3E-200 T 10-11-2016 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 A4G23_RS06400 bf3d82f3badb436462fb0018f25ffa29 451 TIGRFAM TIGR01358 DAHP_synth_II: 3-deoxy-7-phosphoheptulonate synthase 13 450 4.5E-235 T 10-11-2016 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 A4G23_RS06400 bf3d82f3badb436462fb0018f25ffa29 451 SUPERFAMILY SSF51569 11 449 1.45E-197 T 10-11-2016 A4G23_RS15760 9bf599cc48464b780484226b31c45ef1 596 SMART SM00836 481 596 8.4E-39 T 10-11-2016 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 A4G23_RS15760 9bf599cc48464b780484226b31c45ef1 596 PRINTS PR01038 Arginyl-tRNA synthetase signature 118 133 2.1E-23 T 10-11-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A4G23_RS15760 9bf599cc48464b780484226b31c45ef1 596 PRINTS PR01038 Arginyl-tRNA synthetase signature 157 170 2.1E-23 T 10-11-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A4G23_RS15760 9bf599cc48464b780484226b31c45ef1 596 PRINTS PR01038 Arginyl-tRNA synthetase signature 133 149 2.1E-23 T 10-11-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A4G23_RS15760 9bf599cc48464b780484226b31c45ef1 596 PRINTS PR01038 Arginyl-tRNA synthetase signature 318 339 2.1E-23 T 10-11-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A4G23_RS15760 9bf599cc48464b780484226b31c45ef1 596 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 11 89 6.0E-17 T 10-11-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 A4G23_RS15760 9bf599cc48464b780484226b31c45ef1 596 Hamap MF_00123 Arginine--tRNA ligase [argS]. 9 596 25.846 T 10-11-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A4G23_RS15760 9bf599cc48464b780484226b31c45ef1 596 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 12 596 1.0E-130 T 10-11-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A4G23_RS15760 9bf599cc48464b780484226b31c45ef1 596 Pfam PF00750 tRNA synthetases class I (R) 107 466 1.4E-98 T 10-11-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A4G23_RS15760 9bf599cc48464b780484226b31c45ef1 596 Gene3D G3DSA:3.40.50.620 113 473 7.8E-99 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS15760 9bf599cc48464b780484226b31c45ef1 596 SUPERFAMILY SSF47323 475 596 3.6E-32 T 10-11-2016 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4G23_RS15760 9bf599cc48464b780484226b31c45ef1 596 SUPERFAMILY SSF52374 113 473 3.75E-83 T 10-11-2016 A4G23_RS15760 9bf599cc48464b780484226b31c45ef1 596 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 126 137 - T 10-11-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4G23_RS15760 9bf599cc48464b780484226b31c45ef1 596 SUPERFAMILY SSF55190 7 100 2.49E-15 T 10-11-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 A4G23_RS15760 9bf599cc48464b780484226b31c45ef1 596 Pfam PF05746 DALR anticodon binding domain 481 596 3.6E-32 T 10-11-2016 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 A4G23_RS15760 9bf599cc48464b780484226b31c45ef1 596 Gene3D G3DSA:1.10.730.10 475 596 6.0E-34 T 10-11-2016 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4G23_RS15760 9bf599cc48464b780484226b31c45ef1 596 Gene3D G3DSA:3.30.1360.70 6 108 6.8E-25 T 10-11-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 A4G23_RS15760 9bf599cc48464b780484226b31c45ef1 596 SMART SM01016 9 90 1.1E-24 T 10-11-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 A4G23_RS02250 447bb0078f410cecf00d7698f23ab483 139 SUPERFAMILY SSF50692 1 115 1.24E-48 T 10-11-2016 IPR009010 Aspartate decarboxylase-like domain A4G23_RS02250 447bb0078f410cecf00d7698f23ab483 139 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 121 5.7E-52 T 10-11-2016 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 A4G23_RS02250 447bb0078f410cecf00d7698f23ab483 139 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 130 73.51 T 10-11-2016 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 A4G23_RS02250 447bb0078f410cecf00d7698f23ab483 139 PIRSF PIRSF006246 1 129 1.5E-52 T 10-11-2016 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 A4G23_RS02250 447bb0078f410cecf00d7698f23ab483 139 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 114 5.0E-36 T 10-11-2016 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 A4G23_RS02250 447bb0078f410cecf00d7698f23ab483 139 Gene3D G3DSA:2.40.40.20 1 118 1.1E-55 T 10-11-2016 A4G23_RS02250 447bb0078f410cecf00d7698f23ab483 139 Pfam PF02261 Aspartate decarboxylase 1 114 7.5E-52 T 10-11-2016 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 A4G23_RS20920 600002077035877c9c8316ef9750e2ba 311 SUPERFAMILY SSF82114 172 307 3.27E-42 T 10-11-2016 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 A4G23_RS20920 600002077035877c9c8316ef9750e2ba 311 Gene3D G3DSA:2.40.30.30 178 307 6.3E-45 T 10-11-2016 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 Reactome: R-HSA-196843 A4G23_RS20920 600002077035877c9c8316ef9750e2ba 311 Gene3D G3DSA:3.40.50.620 2 177 3.0E-60 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS20920 600002077035877c9c8316ef9750e2ba 311 Pfam PF06574 FAD synthetase 6 152 3.8E-49 T 10-11-2016 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4G23_RS20920 600002077035877c9c8316ef9750e2ba 311 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 13 303 3.1E-63 T 10-11-2016 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4G23_RS20920 600002077035877c9c8316ef9750e2ba 311 SUPERFAMILY SSF52374 10 174 3.38E-32 T 10-11-2016 A4G23_RS20920 600002077035877c9c8316ef9750e2ba 311 SMART SM00904 181 306 2.9E-49 T 10-11-2016 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 A4G23_RS20920 600002077035877c9c8316ef9750e2ba 311 PIRSF PIRSF004491 2 310 1.9E-93 T 10-11-2016 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4G23_RS20920 600002077035877c9c8316ef9750e2ba 311 Pfam PF01687 Riboflavin kinase 182 303 3.1E-32 T 10-11-2016 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 A4G23_RS09790 c17a4129b95a09b6051bc392b3ec9317 277 SUPERFAMILY SSF52540 71 272 1.52E-40 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS09790 c17a4129b95a09b6051bc392b3ec9317 277 SMART SM00382 84 266 1.2E-14 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS09790 c17a4129b95a09b6051bc392b3ec9317 277 Gene3D G3DSA:3.40.50.300 63 271 1.2E-42 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS09790 c17a4129b95a09b6051bc392b3ec9317 277 Pfam PF00005 ABC transporter 76 209 8.2E-16 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS01770 2c5f32191fe0697a7ce43dd99c228c9a 812 SUPERFAMILY SSF51126 237 450 4.04E-15 T 10-11-2016 IPR011050 Pectin lyase fold/virulence factor A4G23_RS01770 2c5f32191fe0697a7ce43dd99c228c9a 812 SMART SM00382 589 728 3.7E-6 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS01770 2c5f32191fe0697a7ce43dd99c228c9a 812 Gene3D G3DSA:3.40.50.300 553 741 9.9E-26 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS01770 2c5f32191fe0697a7ce43dd99c228c9a 812 SMART SM00710 151 173 1200.0 T 10-11-2016 IPR006626 Parallel beta-helix repeat A4G23_RS01770 2c5f32191fe0697a7ce43dd99c228c9a 812 SMART SM00710 385 406 870.0 T 10-11-2016 IPR006626 Parallel beta-helix repeat A4G23_RS01770 2c5f32191fe0697a7ce43dd99c228c9a 812 SMART SM00710 453 475 5500.0 T 10-11-2016 IPR006626 Parallel beta-helix repeat A4G23_RS01770 2c5f32191fe0697a7ce43dd99c228c9a 812 SMART SM00710 174 196 54.0 T 10-11-2016 IPR006626 Parallel beta-helix repeat A4G23_RS01770 2c5f32191fe0697a7ce43dd99c228c9a 812 SMART SM00710 198 220 3200.0 T 10-11-2016 IPR006626 Parallel beta-helix repeat A4G23_RS01770 2c5f32191fe0697a7ce43dd99c228c9a 812 SMART SM00710 362 383 3600.0 T 10-11-2016 IPR006626 Parallel beta-helix repeat A4G23_RS01770 2c5f32191fe0697a7ce43dd99c228c9a 812 SMART SM00710 407 429 310.0 T 10-11-2016 IPR006626 Parallel beta-helix repeat A4G23_RS01770 2c5f32191fe0697a7ce43dd99c228c9a 812 SMART SM00710 339 361 6600.0 T 10-11-2016 IPR006626 Parallel beta-helix repeat A4G23_RS01770 2c5f32191fe0697a7ce43dd99c228c9a 812 SMART SM00710 244 266 4100.0 T 10-11-2016 IPR006626 Parallel beta-helix repeat A4G23_RS01770 2c5f32191fe0697a7ce43dd99c228c9a 812 SMART SM00710 267 289 4000.0 T 10-11-2016 IPR006626 Parallel beta-helix repeat A4G23_RS01770 2c5f32191fe0697a7ce43dd99c228c9a 812 SMART SM00710 221 243 5600.0 T 10-11-2016 IPR006626 Parallel beta-helix repeat A4G23_RS01770 2c5f32191fe0697a7ce43dd99c228c9a 812 SMART SM00710 430 452 380.0 T 10-11-2016 IPR006626 Parallel beta-helix repeat A4G23_RS01770 2c5f32191fe0697a7ce43dd99c228c9a 812 SMART SM00710 128 150 69.0 T 10-11-2016 IPR006626 Parallel beta-helix repeat A4G23_RS01770 2c5f32191fe0697a7ce43dd99c228c9a 812 SMART SM00722 313 474 1.7E-5 T 10-11-2016 IPR006633 Carbohydrate-binding/sugar hydrolysis domain A4G23_RS01770 2c5f32191fe0697a7ce43dd99c228c9a 812 SMART SM00722 41 172 21.0 T 10-11-2016 IPR006633 Carbohydrate-binding/sugar hydrolysis domain A4G23_RS01770 2c5f32191fe0697a7ce43dd99c228c9a 812 SUPERFAMILY SSF51126 20 241 5.54E-27 T 10-11-2016 IPR011050 Pectin lyase fold/virulence factor A4G23_RS01770 2c5f32191fe0697a7ce43dd99c228c9a 812 PRINTS PR00819 CbxX/CfqX superfamily signature 592 607 1.3E-50 T 10-11-2016 IPR000641 CbxX/CfqX GO:0005524 A4G23_RS01770 2c5f32191fe0697a7ce43dd99c228c9a 812 PRINTS PR00819 CbxX/CfqX superfamily signature 630 644 1.3E-50 T 10-11-2016 IPR000641 CbxX/CfqX GO:0005524 A4G23_RS01770 2c5f32191fe0697a7ce43dd99c228c9a 812 PRINTS PR00819 CbxX/CfqX superfamily signature 770 782 1.3E-50 T 10-11-2016 IPR000641 CbxX/CfqX GO:0005524 A4G23_RS01770 2c5f32191fe0697a7ce43dd99c228c9a 812 PRINTS PR00819 CbxX/CfqX superfamily signature 552 566 1.3E-50 T 10-11-2016 IPR000641 CbxX/CfqX GO:0005524 A4G23_RS01770 2c5f32191fe0697a7ce43dd99c228c9a 812 PRINTS PR00819 CbxX/CfqX superfamily signature 696 713 1.3E-50 T 10-11-2016 IPR000641 CbxX/CfqX GO:0005524 A4G23_RS01770 2c5f32191fe0697a7ce43dd99c228c9a 812 PRINTS PR00819 CbxX/CfqX superfamily signature 644 663 1.3E-50 T 10-11-2016 IPR000641 CbxX/CfqX GO:0005524 A4G23_RS01770 2c5f32191fe0697a7ce43dd99c228c9a 812 PRINTS PR00819 CbxX/CfqX superfamily signature 675 687 1.3E-50 T 10-11-2016 IPR000641 CbxX/CfqX GO:0005524 A4G23_RS01770 2c5f32191fe0697a7ce43dd99c228c9a 812 PRINTS PR00819 CbxX/CfqX superfamily signature 713 732 1.3E-50 T 10-11-2016 IPR000641 CbxX/CfqX GO:0005524 A4G23_RS01770 2c5f32191fe0697a7ce43dd99c228c9a 812 Gene3D G3DSA:2.160.20.10 336 471 2.2E-6 T 10-11-2016 IPR012334 Pectin lyase fold A4G23_RS01770 2c5f32191fe0697a7ce43dd99c228c9a 812 Gene3D G3DSA:2.160.20.10 3 255 1.6E-18 T 10-11-2016 IPR012334 Pectin lyase fold A4G23_RS01770 2c5f32191fe0697a7ce43dd99c228c9a 812 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 595 725 2.3E-16 T 10-11-2016 IPR003959 ATPase, AAA-type, core GO:0005524 A4G23_RS01770 2c5f32191fe0697a7ce43dd99c228c9a 812 Pfam PF13229 Right handed beta helix region 119 223 1.0E-10 T 10-11-2016 A4G23_RS01770 2c5f32191fe0697a7ce43dd99c228c9a 812 Pfam PF13229 Right handed beta helix region 238 395 1.9E-9 T 10-11-2016 A4G23_RS01770 2c5f32191fe0697a7ce43dd99c228c9a 812 Pfam PF13229 Right handed beta helix region 401 488 4.3E-7 T 10-11-2016 A4G23_RS01770 2c5f32191fe0697a7ce43dd99c228c9a 812 SUPERFAMILY SSF52540 552 763 6.14E-35 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS03005 be611d433309173e06889a06316ade7b 327 SUPERFAMILY SSF103481 44 140 7.98E-11 T 10-11-2016 A4G23_RS03005 be611d433309173e06889a06316ade7b 327 SUPERFAMILY SSF103481 217 300 7.59E-11 T 10-11-2016 A4G23_RS03005 be611d433309173e06889a06316ade7b 327 Pfam PF00892 EamA-like transporter family 10 139 3.0E-15 T 10-11-2016 IPR000620 EamA domain GO:0016020|GO:0016021 A4G23_RS03005 be611d433309173e06889a06316ade7b 327 Pfam PF00892 EamA-like transporter family 151 295 2.4E-13 T 10-11-2016 IPR000620 EamA domain GO:0016020|GO:0016021 A4G23_RS00195 ad47fcfc076b0a10597efe2d003577e6 458 Gene3D G3DSA:3.60.15.10 12 238 8.0E-45 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS00195 ad47fcfc076b0a10597efe2d003577e6 458 SMART SM00849 13 180 2.6E-19 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS00195 ad47fcfc076b0a10597efe2d003577e6 458 Pfam PF00581 Rhodanese-like domain 360 442 2.7E-5 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS00195 ad47fcfc076b0a10597efe2d003577e6 458 SUPERFAMILY SSF52821 220 352 1.92E-15 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS00195 ad47fcfc076b0a10597efe2d003577e6 458 SMART SM00450 356 450 4.9E-10 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS00195 ad47fcfc076b0a10597efe2d003577e6 458 Gene3D G3DSA:3.40.250.10 352 451 5.3E-15 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS00195 ad47fcfc076b0a10597efe2d003577e6 458 Pfam PF00753 Metallo-beta-lactamase superfamily 15 170 3.4E-8 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS00195 ad47fcfc076b0a10597efe2d003577e6 458 Gene3D G3DSA:3.40.250.10 252 350 7.5E-8 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS00195 ad47fcfc076b0a10597efe2d003577e6 458 SUPERFAMILY SSF52821 341 453 6.94E-20 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS00195 ad47fcfc076b0a10597efe2d003577e6 458 SUPERFAMILY SSF56281 8 243 4.48E-39 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS03485 3312a335c236ef9be4c56842c1197029 227 PIRSF PIRSF001461 1 223 7.0E-96 T 10-11-2016 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 A4G23_RS03485 3312a335c236ef9be4c56842c1197029 227 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 29 43 - T 10-11-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 A4G23_RS03485 3312a335c236ef9be4c56842c1197029 227 Gene3D G3DSA:3.20.20.70 2 218 4.0E-91 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS03485 3312a335c236ef9be4c56842c1197029 227 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 131 153 - T 10-11-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 A4G23_RS03485 3312a335c236ef9be4c56842c1197029 227 Pfam PF00834 Ribulose-phosphate 3 epimerase family 4 198 2.5E-77 T 10-11-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 A4G23_RS03485 3312a335c236ef9be4c56842c1197029 227 SUPERFAMILY SSF51366 2 213 1.36E-63 T 10-11-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 A4G23_RS03485 3312a335c236ef9be4c56842c1197029 227 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 4 211 6.3E-81 T 10-11-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 A4G23_RS23430 a377575fce5456313a5726db134ab1af 473 Gene3D G3DSA:2.60.120.260 306 461 6.3E-29 T 10-11-2016 IPR008979 Galactose-binding domain-like A4G23_RS23430 a377575fce5456313a5726db134ab1af 473 SUPERFAMILY SSF53474 11 238 3.32E-29 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS23430 a377575fce5456313a5726db134ab1af 473 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 325 443 1.2E-15 T 10-11-2016 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 A4G23_RS23430 a377575fce5456313a5726db134ab1af 473 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 14 158 5.9E-31 T 10-11-2016 IPR005674 CocE/Serine esterase GO:0016787 A4G23_RS23430 a377575fce5456313a5726db134ab1af 473 SUPERFAMILY SSF49785 278 456 8.5E-23 T 10-11-2016 IPR008979 Galactose-binding domain-like A4G23_RS23430 a377575fce5456313a5726db134ab1af 473 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 14 232 2.0E-30 T 10-11-2016 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 A4G23_RS23430 a377575fce5456313a5726db134ab1af 473 SMART SM00939 250 453 3.1E-9 T 10-11-2016 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 A4G23_RS23430 a377575fce5456313a5726db134ab1af 473 Gene3D G3DSA:3.40.50.1820 14 136 1.3E-44 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS23430 a377575fce5456313a5726db134ab1af 473 Gene3D G3DSA:3.40.50.1820 179 263 1.3E-44 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS20095 3da4427f4e5990406f3684a16d79335a 190 Pfam PF13302 Acetyltransferase (GNAT) domain 16 152 8.8E-18 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS20095 3da4427f4e5990406f3684a16d79335a 190 Gene3D G3DSA:3.40.630.30 13 182 6.2E-41 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS20095 3da4427f4e5990406f3684a16d79335a 190 SUPERFAMILY SSF55729 9 176 8.29E-36 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS23155 6402e7424da52aba65101ca889f80ac0 301 Gene3D G3DSA:1.10.3720.10 93 283 3.2E-23 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS23155 6402e7424da52aba65101ca889f80ac0 301 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 282 2.3E-18 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS23155 6402e7424da52aba65101ca889f80ac0 301 SUPERFAMILY SSF161098 93 281 1.02E-28 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS05370 e01390cd48848f849a4c22fd79833d41 286 Gene3D G3DSA:2.60.120.620 29 264 3.6E-50 T 10-11-2016 A4G23_RS05370 e01390cd48848f849a4c22fd79833d41 286 SUPERFAMILY SSF51197 29 284 3.85E-58 T 10-11-2016 A4G23_RS05370 e01390cd48848f849a4c22fd79833d41 286 TIGRFAM TIGR02408 ectoine_ThpD: ectoine hydroxylase 17 286 1.8E-147 T 10-11-2016 IPR012774 Ectoine dioxygenase GO:0016706|GO:0055114 A4G23_RS05370 e01390cd48848f849a4c22fd79833d41 286 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 34 249 5.7E-37 T 10-11-2016 IPR008775 Phytanoyl-CoA dioxygenase A4G23_RS21440 d4cba4a0a6f453fe582fc3ef29d50e9d 1112 SUPERFAMILY SSF52210 539 659 3.53E-14 T 10-11-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4G23_RS21440 d4cba4a0a6f453fe582fc3ef29d50e9d 1112 SMART SM00881 211 349 2.5E-16 T 10-11-2016 IPR003781 CoA-binding GO:0048037 A4G23_RS21440 d4cba4a0a6f453fe582fc3ef29d50e9d 1112 SUPERFAMILY SSF51735 313 378 1.65E-14 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS21440 d4cba4a0a6f453fe582fc3ef29d50e9d 1112 Pfam PF13380 CoA binding domain 216 384 6.9E-14 T 10-11-2016 IPR003781 CoA-binding GO:0048037 A4G23_RS21440 d4cba4a0a6f453fe582fc3ef29d50e9d 1112 Gene3D G3DSA:3.40.630.30 21 184 9.2E-24 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS21440 d4cba4a0a6f453fe582fc3ef29d50e9d 1112 SUPERFAMILY SSF55729 30 178 2.84E-24 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS21440 d4cba4a0a6f453fe582fc3ef29d50e9d 1112 SUPERFAMILY SSF56059 893 1096 9.42E-25 T 10-11-2016 A4G23_RS21440 d4cba4a0a6f453fe582fc3ef29d50e9d 1112 Pfam PF00583 Acetyltransferase (GNAT) family 87 170 2.5E-10 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS21440 d4cba4a0a6f453fe582fc3ef29d50e9d 1112 Gene3D G3DSA:3.40.50.261 380 534 5.7E-32 T 10-11-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4G23_RS21440 d4cba4a0a6f453fe582fc3ef29d50e9d 1112 SUPERFAMILY SSF52210 380 539 1.31E-31 T 10-11-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4G23_RS21440 d4cba4a0a6f453fe582fc3ef29d50e9d 1112 Pfam PF13549 ATP-grasp domain 885 1095 2.1E-55 T 10-11-2016 A4G23_RS21440 d4cba4a0a6f453fe582fc3ef29d50e9d 1112 Gene3D G3DSA:3.40.50.720 312 379 9.2E-31 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS21440 d4cba4a0a6f453fe582fc3ef29d50e9d 1112 Gene3D G3DSA:3.40.50.720 198 272 9.2E-31 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS21440 d4cba4a0a6f453fe582fc3ef29d50e9d 1112 SUPERFAMILY SSF51735 205 276 4.6E-10 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS21440 d4cba4a0a6f453fe582fc3ef29d50e9d 1112 Gene3D G3DSA:3.40.50.261 541 647 3.6E-8 T 10-11-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4G23_RS21440 d4cba4a0a6f453fe582fc3ef29d50e9d 1112 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 402 535 3.0E-41 T 10-11-2016 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain A4G23_RS25565 9a26fda38d5fc91c6217ed2baab85c06 168 SUPERFAMILY SSF52218 3 161 5.76E-16 T 10-11-2016 IPR029039 Flavoprotein-like domain A4G23_RS25565 9a26fda38d5fc91c6217ed2baab85c06 168 Gene3D G3DSA:3.40.50.360 3 162 2.8E-18 T 10-11-2016 IPR029039 Flavoprotein-like domain A4G23_RS25565 9a26fda38d5fc91c6217ed2baab85c06 168 Pfam PF12724 Flavodoxin domain 5 130 3.5E-25 T 10-11-2016 IPR026816 Flavodoxin domain A4G23_RS04010 60bfb6aaf35f78cef8070c468fe2ff31 342 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 141 157 - T 10-11-2016 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A4G23_RS04010 60bfb6aaf35f78cef8070c468fe2ff31 342 SUPERFAMILY SSF51735 3 170 8.85E-45 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS04010 60bfb6aaf35f78cef8070c468fe2ff31 342 Gene3D G3DSA:3.40.50.720 1 154 7.8E-53 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS04010 60bfb6aaf35f78cef8070c468fe2ff31 342 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 3 336 39.06 T 10-11-2016 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A4G23_RS04010 60bfb6aaf35f78cef8070c468fe2ff31 342 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 155 313 3.3E-24 T 10-11-2016 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A4G23_RS04010 60bfb6aaf35f78cef8070c468fe2ff31 342 SMART SM00859 4 136 5.1E-43 T 10-11-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 A4G23_RS04010 60bfb6aaf35f78cef8070c468fe2ff31 342 Gene3D G3DSA:3.30.360.10 155 310 1.7E-60 T 10-11-2016 A4G23_RS04010 60bfb6aaf35f78cef8070c468fe2ff31 342 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 3 342 4.7E-120 T 10-11-2016 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A4G23_RS04010 60bfb6aaf35f78cef8070c468fe2ff31 342 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 4 129 2.4E-25 T 10-11-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 A4G23_RS04010 60bfb6aaf35f78cef8070c468fe2ff31 342 SUPERFAMILY SSF55347 146 310 1.96E-50 T 10-11-2016 A4G23_RS10075 c122cd9fd7c2ad98e559e6c951268e85 292 SUPERFAMILY SSF103481 178 277 2.75E-13 T 10-11-2016 A4G23_RS10075 c122cd9fd7c2ad98e559e6c951268e85 292 SUPERFAMILY SSF103481 29 128 5.1E-6 T 10-11-2016 A4G23_RS10075 c122cd9fd7c2ad98e559e6c951268e85 292 Pfam PF00892 EamA-like transporter family 2 125 2.2E-11 T 10-11-2016 IPR000620 EamA domain GO:0016020|GO:0016021 A4G23_RS10075 c122cd9fd7c2ad98e559e6c951268e85 292 Pfam PF00892 EamA-like transporter family 134 272 1.2E-17 T 10-11-2016 IPR000620 EamA domain GO:0016020|GO:0016021 A4G23_RS20535 73ce9320e256125aaf0c41fceecdef3d 288 Gene3D G3DSA:2.10.109.10 54 146 1.0E-39 T 10-11-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain A4G23_RS20535 73ce9320e256125aaf0c41fceecdef3d 288 Gene3D G3DSA:2.10.109.10 186 238 1.0E-39 T 10-11-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain A4G23_RS20535 73ce9320e256125aaf0c41fceecdef3d 288 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 45 232 3.8E-42 T 10-11-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A4G23_RS20535 73ce9320e256125aaf0c41fceecdef3d 288 ProSitePatterns PS00761 Signal peptidases I signature 3. 191 204 - T 10-11-2016 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 A4G23_RS20535 73ce9320e256125aaf0c41fceecdef3d 288 Pfam PF00717 Peptidase S24-like 65 161 1.6E-15 T 10-11-2016 IPR019759 Peptidase S24/S26A/S26B A4G23_RS20535 73ce9320e256125aaf0c41fceecdef3d 288 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 136 148 1.1E-20 T 10-11-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A4G23_RS20535 73ce9320e256125aaf0c41fceecdef3d 288 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 58 74 1.1E-20 T 10-11-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A4G23_RS20535 73ce9320e256125aaf0c41fceecdef3d 288 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 186 205 1.1E-20 T 10-11-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A4G23_RS20535 73ce9320e256125aaf0c41fceecdef3d 288 SUPERFAMILY SSF51306 57 238 6.15E-47 T 10-11-2016 IPR015927 Peptidase S24/S26A/S26B/S26C A4G23_RS23460 825fd9e061aaa708c31bbe805c3d5721 365 Pfam PF13478 XdhC Rossmann domain 201 343 6.8E-43 T 10-11-2016 IPR027051 XdhC Rossmann domain A4G23_RS23460 825fd9e061aaa708c31bbe805c3d5721 365 Pfam PF02625 XdhC and CoxI family 114 178 2.4E-13 T 10-11-2016 IPR003777 XdhC- CoxI A4G23_RS23460 825fd9e061aaa708c31bbe805c3d5721 365 Pfam PF02625 XdhC and CoxI family 11 77 1.0E-23 T 10-11-2016 IPR003777 XdhC- CoxI A4G23_RS02080 0947b3fada51072464a03cc5cc19b43f 167 Pfam PF01037 Lrp/AsnC ligand binding domain 69 139 1.5E-20 T 10-11-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A4G23_RS02080 0947b3fada51072464a03cc5cc19b43f 167 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 50 9.9E-14 T 10-11-2016 A4G23_RS02080 0947b3fada51072464a03cc5cc19b43f 167 SUPERFAMILY SSF54909 64 148 4.29E-20 T 10-11-2016 IPR011008 Dimeric alpha-beta barrel A4G23_RS02080 0947b3fada51072464a03cc5cc19b43f 167 Gene3D G3DSA:3.30.70.920 56 134 2.7E-23 T 10-11-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A4G23_RS02080 0947b3fada51072464a03cc5cc19b43f 167 Gene3D G3DSA:1.10.10.10 2 52 1.9E-14 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS02080 0947b3fada51072464a03cc5cc19b43f 167 SMART SM00344 3 109 3.9E-26 T 10-11-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A4G23_RS02080 0947b3fada51072464a03cc5cc19b43f 167 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 7.7E-10 T 10-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 A4G23_RS02080 0947b3fada51072464a03cc5cc19b43f 167 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 7.7E-10 T 10-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 A4G23_RS02080 0947b3fada51072464a03cc5cc19b43f 167 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 7.7E-10 T 10-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 A4G23_RS02080 0947b3fada51072464a03cc5cc19b43f 167 SUPERFAMILY SSF46785 3 63 2.79E-11 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS09480 aaada114873a16f993b72d2a4d3098de 113 SUPERFAMILY SSF54736 34 108 3.56E-25 T 10-11-2016 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like A4G23_RS09480 aaada114873a16f993b72d2a4d3098de 113 Gene3D G3DSA:3.30.1390.10 22 111 1.5E-29 T 10-11-2016 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like A4G23_RS09480 aaada114873a16f993b72d2a4d3098de 113 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 24 112 17.431 T 10-11-2016 IPR022935 ATP-dependent Clp protease adaptor protein ClpS A4G23_RS09480 aaada114873a16f993b72d2a4d3098de 113 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 37 106 8.9E-23 T 10-11-2016 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 A4G23_RS21575 955b637c5bc2abb71b307b919df012a1 444 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 422 432 - T 10-11-2016 IPR030391 RNA methyltransferase TrmA, conserved site A4G23_RS21575 955b637c5bc2abb71b307b919df012a1 444 Gene3D G3DSA:2.40.50.140 8 87 3.7E-22 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS21575 955b637c5bc2abb71b307b919df012a1 444 SUPERFAMILY SSF53335 77 439 7.63E-57 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS21575 955b637c5bc2abb71b307b919df012a1 444 SUPERFAMILY SSF50249 5 59 1.26E-10 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS21575 955b637c5bc2abb71b307b919df012a1 444 Gene3D G3DSA:3.40.50.150 245 438 2.3E-50 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS21575 955b637c5bc2abb71b307b919df012a1 444 Pfam PF01938 TRAM domain 9 69 3.2E-14 T 10-11-2016 IPR002792 TRAM domain A4G23_RS21575 955b637c5bc2abb71b307b919df012a1 444 Pfam PF13847 Methyltransferase domain 293 385 1.8E-10 T 10-11-2016 IPR025714 Methyltransferase domain A4G23_RS12095 c2c714efeedd3607832dc21a7653103b 192 SUPERFAMILY SSF143744 57 189 1.7E-32 T 10-11-2016 A4G23_RS12095 c2c714efeedd3607832dc21a7653103b 192 Pfam PF03928 Haem-degrading 64 186 2.7E-30 T 10-11-2016 IPR005624 Haem-degrading A4G23_RS01380 39024827d5cd4078377f6abb354670d4 131 Pfam PF10025 Uncharacterized conserved protein (DUF2267) 6 122 8.2E-20 T 10-11-2016 IPR018727 Protein of unknown function DUF2267 A4G23_RS10240 d3e41abd527e297d581c832031fc93fc 552 TIGRFAM TIGR01228 hutU: urocanate hydratase 6 548 7.9E-272 T 10-11-2016 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A4G23_RS10240 d3e41abd527e297d581c832031fc93fc 552 ProSitePatterns PS01233 Urocanase signature. 436 451 - T 10-11-2016 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A4G23_RS10240 d3e41abd527e297d581c832031fc93fc 552 SUPERFAMILY SSF111326 4 549 4.84E-246 T 10-11-2016 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A4G23_RS10240 d3e41abd527e297d581c832031fc93fc 552 Gene3D G3DSA:3.40.1770.10 354 548 2.7E-151 T 10-11-2016 A4G23_RS10240 d3e41abd527e297d581c832031fc93fc 552 Gene3D G3DSA:3.40.1770.10 6 136 2.7E-151 T 10-11-2016 A4G23_RS10240 d3e41abd527e297d581c832031fc93fc 552 PIRSF PIRSF001423 1 552 1.4E-276 T 10-11-2016 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A4G23_RS10240 d3e41abd527e297d581c832031fc93fc 552 Gene3D G3DSA:3.40.50.10730 137 343 4.4E-83 T 10-11-2016 A4G23_RS10240 d3e41abd527e297d581c832031fc93fc 552 Pfam PF01175 Urocanase 7 541 4.8E-251 T 10-11-2016 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A4G23_RS10240 d3e41abd527e297d581c832031fc93fc 552 Hamap MF_00577 Urocanate hydratase [hutU]. 2 550 49.012 T 10-11-2016 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A4G23_RS17265 c543ef66cd197a3e47e4a94119bd466a 499 Pfam PF00732 GMC oxidoreductase 1 280 6.9E-54 T 10-11-2016 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 A4G23_RS17265 c543ef66cd197a3e47e4a94119bd466a 499 Gene3D G3DSA:3.50.50.60 169 297 3.1E-101 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS17265 c543ef66cd197a3e47e4a94119bd466a 499 Gene3D G3DSA:3.50.50.60 431 494 3.1E-101 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS17265 c543ef66cd197a3e47e4a94119bd466a 499 Gene3D G3DSA:3.50.50.60 1 117 3.1E-101 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS17265 c543ef66cd197a3e47e4a94119bd466a 499 Pfam PF05199 GMC oxidoreductase 350 490 3.1E-42 T 10-11-2016 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 A4G23_RS17265 c543ef66cd197a3e47e4a94119bd466a 499 SUPERFAMILY SSF54373 274 438 1.77E-41 T 10-11-2016 A4G23_RS17265 c543ef66cd197a3e47e4a94119bd466a 499 SUPERFAMILY SSF51905 437 497 1.3E-66 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS17265 c543ef66cd197a3e47e4a94119bd466a 499 SUPERFAMILY SSF51905 1 272 1.3E-66 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS17265 c543ef66cd197a3e47e4a94119bd466a 499 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 238 252 - T 10-11-2016 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 A4G23_RS06740 6df93a2df09955506e6e9c0eba743d76 430 PRINTS PR00419 Adrenodoxin reductase family signature 9 31 7.0E-5 T 10-11-2016 A4G23_RS06740 6df93a2df09955506e6e9c0eba743d76 430 PRINTS PR00419 Adrenodoxin reductase family signature 32 45 7.0E-5 T 10-11-2016 A4G23_RS06740 6df93a2df09955506e6e9c0eba743d76 430 Gene3D G3DSA:3.50.50.60 375 417 5.5E-31 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS06740 6df93a2df09955506e6e9c0eba743d76 430 Gene3D G3DSA:3.50.50.60 8 46 5.5E-31 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS06740 6df93a2df09955506e6e9c0eba743d76 430 Gene3D G3DSA:3.50.50.60 209 276 5.5E-31 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS06740 6df93a2df09955506e6e9c0eba743d76 430 Pfam PF01593 Flavin containing amine oxidoreductase 17 412 6.7E-36 T 10-11-2016 IPR002937 Amine oxidase GO:0016491|GO:0055114 A4G23_RS06740 6df93a2df09955506e6e9c0eba743d76 430 SUPERFAMILY SSF51905 7 273 2.02E-44 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS06740 6df93a2df09955506e6e9c0eba743d76 430 SUPERFAMILY SSF51905 372 415 2.02E-44 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS24685 ae59fd7c2eac362a6d6d208a17b25510 354 Pfam PF04679 ATP dependent DNA ligase C terminal region 215 329 5.1E-15 T 10-11-2016 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 A4G23_RS24685 ae59fd7c2eac362a6d6d208a17b25510 354 Gene3D G3DSA:3.30.1490.70 3 31 5.3E-11 T 10-11-2016 A4G23_RS24685 ae59fd7c2eac362a6d6d208a17b25510 354 Gene3D G3DSA:3.30.1490.70 156 198 5.3E-11 T 10-11-2016 A4G23_RS24685 ae59fd7c2eac362a6d6d208a17b25510 354 SUPERFAMILY SSF56091 6 197 1.63E-45 T 10-11-2016 A4G23_RS24685 ae59fd7c2eac362a6d6d208a17b25510 354 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 27 35 - T 10-11-2016 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 A4G23_RS24685 ae59fd7c2eac362a6d6d208a17b25510 354 SUPERFAMILY SSF50249 200 334 1.29E-13 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS24685 ae59fd7c2eac362a6d6d208a17b25510 354 Pfam PF01068 ATP dependent DNA ligase domain 11 197 1.4E-40 T 10-11-2016 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 A4G23_RS24685 ae59fd7c2eac362a6d6d208a17b25510 354 Gene3D G3DSA:2.40.50.140 200 334 1.9E-13 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS24685 ae59fd7c2eac362a6d6d208a17b25510 354 Gene3D G3DSA:3.30.470.30 32 149 4.4E-31 T 10-11-2016 A4G23_RS08810 9904fc88c1fd691fa1f3cbd7320b34f6 263 Gene3D G3DSA:3.20.20.150 1 254 3.0E-56 T 10-11-2016 IPR013022 Xylose isomerase-like, TIM barrel domain A4G23_RS08810 9904fc88c1fd691fa1f3cbd7320b34f6 263 Pfam PF01261 Xylose isomerase-like TIM barrel 20 212 1.3E-32 T 10-11-2016 IPR013022 Xylose isomerase-like, TIM barrel domain A4G23_RS08810 9904fc88c1fd691fa1f3cbd7320b34f6 263 SUPERFAMILY SSF51658 5 249 3.01E-42 T 10-11-2016 IPR013022 Xylose isomerase-like, TIM barrel domain A4G23_RS05495 3617e06e9dbb1eacfd7fcf84f56464df 463 Gene3D G3DSA:2.120.10.30 303 442 5.8E-6 T 10-11-2016 IPR011042 Six-bladed beta-propeller, TolB-like A4G23_RS05495 3617e06e9dbb1eacfd7fcf84f56464df 463 SUPERFAMILY SSF63829 184 259 1.11E-9 T 10-11-2016 A4G23_RS05495 3617e06e9dbb1eacfd7fcf84f56464df 463 SUPERFAMILY SSF63829 319 450 1.11E-9 T 10-11-2016 A4G23_RS05495 3617e06e9dbb1eacfd7fcf84f56464df 463 Pfam PF05787 Bacterial protein of unknown function (DUF839) 143 448 6.1E-61 T 10-11-2016 IPR008557 Protein of unknown function DUF839 A4G23_RS04050 1b821ce79b1b1aa841dd86d500a50670 500 SUPERFAMILY SSF103473 243 442 1.19E-23 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS04050 1b821ce79b1b1aa841dd86d500a50670 500 SUPERFAMILY SSF103473 10 170 1.19E-23 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS04050 1b821ce79b1b1aa841dd86d500a50670 500 Gene3D G3DSA:1.20.1250.20 259 436 1.0E-12 T 10-11-2016 A4G23_RS04050 1b821ce79b1b1aa841dd86d500a50670 500 Gene3D G3DSA:1.20.1250.20 16 156 4.5E-5 T 10-11-2016 A4G23_RS04050 1b821ce79b1b1aa841dd86d500a50670 500 Pfam PF07690 Major Facilitator Superfamily 14 402 3.7E-13 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS12210 d2bb9595dabd694520fc3ae54671b898 410 Gene3D G3DSA:3.30.565.10 208 379 3.3E-47 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS12210 d2bb9595dabd694520fc3ae54671b898 410 SUPERFAMILY SSF55874 211 380 1.06E-45 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS12210 d2bb9595dabd694520fc3ae54671b898 410 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 268 381 9.0E-23 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS12210 d2bb9595dabd694520fc3ae54671b898 410 SUPERFAMILY SSF47384 138 221 1.29E-16 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS12210 d2bb9595dabd694520fc3ae54671b898 410 SMART SM00388 155 221 8.4E-15 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS12210 d2bb9595dabd694520fc3ae54671b898 410 PRINTS PR00344 Bacterial sensor protein C-terminal signature 342 360 1.3E-21 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS12210 d2bb9595dabd694520fc3ae54671b898 410 PRINTS PR00344 Bacterial sensor protein C-terminal signature 325 335 1.3E-21 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS12210 d2bb9595dabd694520fc3ae54671b898 410 PRINTS PR00344 Bacterial sensor protein C-terminal signature 307 321 1.3E-21 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS12210 d2bb9595dabd694520fc3ae54671b898 410 PRINTS PR00344 Bacterial sensor protein C-terminal signature 366 379 1.3E-21 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS12210 d2bb9595dabd694520fc3ae54671b898 410 SMART SM00387 266 382 2.6E-38 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS12210 d2bb9595dabd694520fc3ae54671b898 410 Gene3D G3DSA:1.10.287.130 147 207 4.6E-14 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS12210 d2bb9595dabd694520fc3ae54671b898 410 Pfam PF00512 His Kinase A (phospho-acceptor) domain 156 219 1.5E-12 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS18060 4773a5d26f1db526bcbcdb5c3383794d 252 Gene3D G3DSA:1.10.10.10 2 71 8.9E-22 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS18060 4773a5d26f1db526bcbcdb5c3383794d 252 Pfam PF01614 Bacterial transcriptional regulator 117 238 9.1E-28 T 10-11-2016 IPR014757 Transcription regulator IclR, C-terminal A4G23_RS18060 4773a5d26f1db526bcbcdb5c3383794d 252 SUPERFAMILY SSF55781 57 239 2.22E-49 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS18060 4773a5d26f1db526bcbcdb5c3383794d 252 SUPERFAMILY SSF46785 3 72 2.38E-16 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS18060 4773a5d26f1db526bcbcdb5c3383794d 252 Gene3D G3DSA:3.30.450.40 72 246 1.0E-56 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS18060 4773a5d26f1db526bcbcdb5c3383794d 252 Pfam PF09339 IclR helix-turn-helix domain 4 52 6.2E-14 T 10-11-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4G23_RS18060 4773a5d26f1db526bcbcdb5c3383794d 252 SMART SM00346 2 89 2.8E-23 T 10-11-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4G23_RS24970 e1e0548bdcde6017293fdf5cda3edf19 211 PIRSF PIRSF001296 8 211 1.6E-68 T 10-11-2016 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 A4G23_RS24970 e1e0548bdcde6017293fdf5cda3edf19 211 Hamap MF_00276 Potassium-transporting ATPase KdpC subunit [kdpC]. 9 208 32.706 T 10-11-2016 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 A4G23_RS24970 e1e0548bdcde6017293fdf5cda3edf19 211 Pfam PF02669 K+-transporting ATPase, c chain 13 206 1.8E-67 T 10-11-2016 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 A4G23_RS24970 e1e0548bdcde6017293fdf5cda3edf19 211 TIGRFAM TIGR00681 kdpC: K+-transporting ATPase, C subunit 14 207 3.6E-51 T 10-11-2016 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 A4G23_RS02165 d266fc792e0e99fe568837eaf001bec7 329 Gene3D G3DSA:1.10.3720.10 86 317 4.8E-65 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS02165 d266fc792e0e99fe568837eaf001bec7 329 SUPERFAMILY SSF161098 80 309 8.11E-60 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS02165 d266fc792e0e99fe568837eaf001bec7 329 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 312 1.4E-16 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS14775 923ca384c2d9d3afbae35889adffbda6 333 Gene3D G3DSA:3.40.50.300 14 240 2.6E-68 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS14775 923ca384c2d9d3afbae35889adffbda6 333 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS14775 923ca384c2d9d3afbae35889adffbda6 333 Pfam PF00005 ABC transporter 36 179 4.1E-26 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS14775 923ca384c2d9d3afbae35889adffbda6 333 SMART SM00382 45 235 5.9E-11 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS14775 923ca384c2d9d3afbae35889adffbda6 333 SUPERFAMILY SSF52540 21 239 2.88E-58 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS14775 923ca384c2d9d3afbae35889adffbda6 333 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 28 320 5.4E-94 T 10-11-2016 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 A4G23_RS02000 42af4d1bf70eb23ce138a22236475ca5 202 SUPERFAMILY SSF46689 12 92 2.57E-17 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS02000 42af4d1bf70eb23ce138a22236475ca5 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 9.4E-8 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS02000 42af4d1bf70eb23ce138a22236475ca5 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 9.4E-8 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS02000 42af4d1bf70eb23ce138a22236475ca5 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 4.0E-15 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS02000 42af4d1bf70eb23ce138a22236475ca5 202 ProSitePatterns PS01081 TetR-type HTH domain signature. 32 63 - T 10-11-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A4G23_RS02000 42af4d1bf70eb23ce138a22236475ca5 202 Gene3D G3DSA:1.10.357.10 17 180 1.2E-29 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS08580 80ba25422e1f8b6310d94e09e5d7a124 65 Pfam PF12728 Helix-turn-helix domain 10 61 2.8E-13 T 10-11-2016 A4G23_RS08580 80ba25422e1f8b6310d94e09e5d7a124 65 SUPERFAMILY SSF46955 10 61 4.03E-7 T 10-11-2016 IPR009061 Putative DNA-binding domain A4G23_RS08580 80ba25422e1f8b6310d94e09e5d7a124 65 Gene3D G3DSA:1.10.10.10 10 62 2.6E-5 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS18645 43f4c2208b53be074104939907b48ece 710 Gene3D G3DSA:3.40.50.300 4 235 5.3E-73 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS18645 43f4c2208b53be074104939907b48ece 710 SUPERFAMILY SSF52540 87 375 9.87E-73 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS18645 43f4c2208b53be074104939907b48ece 710 Pfam PF00270 DEAD/DEAH box helicase 30 203 1.2E-49 T 10-11-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A4G23_RS18645 43f4c2208b53be074104939907b48ece 710 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 166 174 - T 10-11-2016 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site A4G23_RS18645 43f4c2208b53be074104939907b48ece 710 SMART SM00490 274 355 3.9E-32 T 10-11-2016 IPR001650 Helicase, C-terminal A4G23_RS18645 43f4c2208b53be074104939907b48ece 710 Pfam PF00271 Helicase conserved C-terminal domain 246 355 8.1E-28 T 10-11-2016 IPR001650 Helicase, C-terminal A4G23_RS18645 43f4c2208b53be074104939907b48ece 710 SMART SM00487 25 238 2.2E-53 T 10-11-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4G23_RS18645 43f4c2208b53be074104939907b48ece 710 Gene3D G3DSA:3.40.50.300 236 380 9.5E-49 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS01535 edf9d51dcc36b6df35707453836c1ac8 374 SUPERFAMILY SSF51445 67 364 5.55E-44 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS01535 edf9d51dcc36b6df35707453836c1ac8 374 Gene3D G3DSA:3.20.20.80 68 364 1.0E-41 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS01535 edf9d51dcc36b6df35707453836c1ac8 374 Pfam PF00704 Glycosyl hydrolases family 18 70 273 3.6E-21 T 10-11-2016 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0004553|GO:0005975 A4G23_RS01535 edf9d51dcc36b6df35707453836c1ac8 374 SMART SM00636 68 357 5.9E-4 T 10-11-2016 IPR011583 Chitinase II GO:0004568|GO:0006032 A4G23_RS01535 edf9d51dcc36b6df35707453836c1ac8 374 ProSitePatterns PS01095 Chitinases family 18 active site. 182 190 - T 10-11-2016 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 A4G23_RS27095 8552ca5ece4ffe8a712ed61ddcdc5090 142 Pfam PF13649 Methyltransferase domain 23 125 8.3E-15 T 10-11-2016 A4G23_RS27095 8552ca5ece4ffe8a712ed61ddcdc5090 142 SUPERFAMILY SSF53335 8 134 7.64E-27 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS27095 8552ca5ece4ffe8a712ed61ddcdc5090 142 Gene3D G3DSA:3.40.50.150 8 135 1.0E-23 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS23015 affc41cf5266f98b55c70c1ce00bc4ec 474 Pfam PF05787 Bacterial protein of unknown function (DUF839) 160 464 1.2E-68 T 10-11-2016 IPR008557 Protein of unknown function DUF839 A4G23_RS23015 affc41cf5266f98b55c70c1ce00bc4ec 474 Pfam PF05787 Bacterial protein of unknown function (DUF839) 59 151 1.4E-13 T 10-11-2016 IPR008557 Protein of unknown function DUF839 A4G23_RS23015 affc41cf5266f98b55c70c1ce00bc4ec 474 SUPERFAMILY SSF50956 352 462 5.49E-10 T 10-11-2016 A4G23_RS23015 affc41cf5266f98b55c70c1ce00bc4ec 474 Gene3D G3DSA:2.120.10.30 352 462 2.3E-5 T 10-11-2016 IPR011042 Six-bladed beta-propeller, TolB-like A4G23_RS03135 24d7dc1385103b122f5ee17e14df18fc 790 SUPERFAMILY SSF51011 628 707 4.75E-19 T 10-11-2016 A4G23_RS03135 24d7dc1385103b122f5ee17e14df18fc 790 SUPERFAMILY SSF74650 91 271 1.41E-13 T 10-11-2016 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 A4G23_RS03135 24d7dc1385103b122f5ee17e14df18fc 790 Pfam PF01055 Glycosyl hydrolases family 31 268 712 3.7E-122 T 10-11-2016 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 A4G23_RS03135 24d7dc1385103b122f5ee17e14df18fc 790 ProSitePatterns PS00129 Glycosyl hydrolases family 31 active site. 439 446 - T 10-11-2016 IPR030458 Glycosyl hydrolases family 31, active site A4G23_RS03135 24d7dc1385103b122f5ee17e14df18fc 790 Pfam PF13802 Galactose mutarotase-like 170 235 4.9E-8 T 10-11-2016 IPR025887 Glycoside hydrolase family 31, N-terminal domain A4G23_RS03135 24d7dc1385103b122f5ee17e14df18fc 790 SUPERFAMILY SSF51445 277 626 8.43E-82 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS01935 ee2d16b7268ea1d0530bce70903dc462 320 Pfam PF01012 Electron transfer flavoprotein domain 4 173 4.2E-29 T 10-11-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 A4G23_RS01935 ee2d16b7268ea1d0530bce70903dc462 320 SUPERFAMILY SSF52402 3 188 1.4E-36 T 10-11-2016 A4G23_RS01935 ee2d16b7268ea1d0530bce70903dc462 320 SMART SM00893 4 187 7.2E-26 T 10-11-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 A4G23_RS01935 ee2d16b7268ea1d0530bce70903dc462 320 Gene3D G3DSA:3.40.50.620 3 185 2.3E-37 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS01935 ee2d16b7268ea1d0530bce70903dc462 320 Gene3D G3DSA:3.40.50.1220 190 316 7.6E-59 T 10-11-2016 IPR029035 DHS-like NAD/FAD-binding domain A4G23_RS01935 ee2d16b7268ea1d0530bce70903dc462 320 PIRSF PIRSF000089 1 320 2.8E-98 T 10-11-2016 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 A4G23_RS01935 ee2d16b7268ea1d0530bce70903dc462 320 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 259 285 - T 10-11-2016 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 A4G23_RS01935 ee2d16b7268ea1d0530bce70903dc462 320 SUPERFAMILY SSF52467 194 314 1.7E-47 T 10-11-2016 IPR029035 DHS-like NAD/FAD-binding domain A4G23_RS01935 ee2d16b7268ea1d0530bce70903dc462 320 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 196 278 1.5E-35 T 10-11-2016 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 A4G23_RS20750 8e96aa1853eee776c68ad91bb254c015 445 Gene3D G3DSA:3.40.640.10 57 334 1.6E-78 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS20750 8e96aa1853eee776c68ad91bb254c015 445 PIRSF PIRSF000521 24 436 2.0E-32 T 10-11-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4G23_RS20750 8e96aa1853eee776c68ad91bb254c015 445 Gene3D G3DSA:3.90.1150.10 10 56 6.8E-33 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS20750 8e96aa1853eee776c68ad91bb254c015 445 Gene3D G3DSA:3.90.1150.10 337 436 6.8E-33 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS20750 8e96aa1853eee776c68ad91bb254c015 445 Pfam PF00202 Aminotransferase class-III 22 431 4.8E-99 T 10-11-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4G23_RS20750 8e96aa1853eee776c68ad91bb254c015 445 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 245 282 - T 10-11-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4G23_RS20750 8e96aa1853eee776c68ad91bb254c015 445 SUPERFAMILY SSF53383 11 433 1.14E-111 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS08300 cd4a6259f7ad7c3cc5689822b9823a7b 427 Gene3D G3DSA:3.40.50.300 62 256 5.3E-47 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS08300 cd4a6259f7ad7c3cc5689822b9823a7b 427 Gene3D G3DSA:3.40.50.300 295 312 5.3E-47 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS08300 cd4a6259f7ad7c3cc5689822b9823a7b 427 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 318 395 8.9E-15 T 10-11-2016 IPR019489 Clp ATPase, C-terminal A4G23_RS08300 cd4a6259f7ad7c3cc5689822b9823a7b 427 Gene3D G3DSA:1.10.8.60 317 413 8.0E-35 T 10-11-2016 A4G23_RS08300 cd4a6259f7ad7c3cc5689822b9823a7b 427 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 9 412 1.1E-196 T 10-11-2016 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 A4G23_RS08300 cd4a6259f7ad7c3cc5689822b9823a7b 427 Pfam PF06689 ClpX C4-type zinc finger 11 48 8.9E-21 T 10-11-2016 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 A4G23_RS08300 cd4a6259f7ad7c3cc5689822b9823a7b 427 SMART SM01086 318 412 8.6E-30 T 10-11-2016 IPR019489 Clp ATPase, C-terminal A4G23_RS08300 cd4a6259f7ad7c3cc5689822b9823a7b 427 SMART SM00382 114 266 4.2E-11 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS08300 cd4a6259f7ad7c3cc5689822b9823a7b 427 SUPERFAMILY SSF57716 11 46 1.37E-11 T 10-11-2016 A4G23_RS08300 cd4a6259f7ad7c3cc5689822b9823a7b 427 SUPERFAMILY SSF52540 58 403 6.19E-74 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS08300 cd4a6259f7ad7c3cc5689822b9823a7b 427 SMART SM00994 10 49 1.1E-23 T 10-11-2016 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 A4G23_RS08300 cd4a6259f7ad7c3cc5689822b9823a7b 427 Pfam PF07724 AAA domain (Cdc48 subfamily) 115 312 1.9E-51 T 10-11-2016 IPR003959 ATPase, AAA-type, core GO:0005524 A4G23_RS08300 cd4a6259f7ad7c3cc5689822b9823a7b 427 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 416 52.573 T 10-11-2016 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 A4G23_RS01480 eacf272dae44ed063273495e29741f24 363 SUPERFAMILY SSF55931 3 361 5.4E-90 T 10-11-2016 A4G23_RS01480 eacf272dae44ed063273495e29741f24 363 TIGRFAM TIGR02050 gshA_cyan_rel: carboxylate-amine ligase, YbdK family 4 289 2.9E-97 T 10-11-2016 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 A4G23_RS01480 eacf272dae44ed063273495e29741f24 363 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 4 284 5.2E-59 T 10-11-2016 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 A4G23_RS01480 eacf272dae44ed063273495e29741f24 363 Hamap MF_01609 Glutamate--cysteine ligase [gshA]. 1 363 75.662 T 10-11-2016 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 A4G23_RS05970 f4b3ff58bb9737da217743800f632124 308 Pfam PF00294 pfkB family carbohydrate kinase 10 294 2.1E-65 T 10-11-2016 IPR011611 Carbohydrate kinase PfkB A4G23_RS05970 f4b3ff58bb9737da217743800f632124 308 Gene3D G3DSA:3.40.1190.20 8 301 5.2E-99 T 10-11-2016 IPR029056 Ribokinase-like A4G23_RS05970 f4b3ff58bb9737da217743800f632124 308 Hamap MF_01987 Ribokinase [rbsK]. 9 301 26.97 T 10-11-2016 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15 A4G23_RS05970 f4b3ff58bb9737da217743800f632124 308 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 246 259 - T 10-11-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A4G23_RS05970 f4b3ff58bb9737da217743800f632124 308 SUPERFAMILY SSF53613 9 297 4.21E-78 T 10-11-2016 IPR029056 Ribokinase-like A4G23_RS05970 f4b3ff58bb9737da217743800f632124 308 PRINTS PR00990 Ribokinase signature 111 124 1.9E-37 T 10-11-2016 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 A4G23_RS05970 f4b3ff58bb9737da217743800f632124 308 PRINTS PR00990 Ribokinase signature 13 34 1.9E-37 T 10-11-2016 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 A4G23_RS05970 f4b3ff58bb9737da217743800f632124 308 PRINTS PR00990 Ribokinase signature 178 193 1.9E-37 T 10-11-2016 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 A4G23_RS05970 f4b3ff58bb9737da217743800f632124 308 PRINTS PR00990 Ribokinase signature 216 227 1.9E-37 T 10-11-2016 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 A4G23_RS05970 f4b3ff58bb9737da217743800f632124 308 PRINTS PR00990 Ribokinase signature 40 59 1.9E-37 T 10-11-2016 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 A4G23_RS05970 f4b3ff58bb9737da217743800f632124 308 TIGRFAM TIGR02152 D_ribokin_bact: ribokinase 11 299 5.8E-94 T 10-11-2016 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15 A4G23_RS15515 10b3653696861f16676d6358ab4138b7 816 Pfam PF00069 Protein kinase domain 23 269 2.7E-36 T 10-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4G23_RS15515 10b3653696861f16676d6358ab4138b7 816 Pfam PF13360 PQQ-like domain 450 602 1.4E-7 T 10-11-2016 IPR002372 Pyrrolo-quinoline quinone repeat A4G23_RS15515 10b3653696861f16676d6358ab4138b7 816 Pfam PF13360 PQQ-like domain 689 814 2.7E-8 T 10-11-2016 IPR002372 Pyrrolo-quinoline quinone repeat A4G23_RS15515 10b3653696861f16676d6358ab4138b7 816 Gene3D G3DSA:1.10.510.10 105 269 1.6E-42 T 10-11-2016 A4G23_RS15515 10b3653696861f16676d6358ab4138b7 816 SUPERFAMILY SSF56112 19 271 1.75E-62 T 10-11-2016 IPR011009 Protein kinase-like domain A4G23_RS15515 10b3653696861f16676d6358ab4138b7 816 Gene3D G3DSA:2.140.10.10 442 813 2.9E-31 T 10-11-2016 IPR027295 Quinoprotein alcohol dehydrogenase-like domain A4G23_RS15515 10b3653696861f16676d6358ab4138b7 816 SMART SM00220 22 273 7.0E-39 T 10-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4G23_RS15515 10b3653696861f16676d6358ab4138b7 816 Gene3D G3DSA:3.30.200.20 14 96 2.6E-13 T 10-11-2016 A4G23_RS15515 10b3653696861f16676d6358ab4138b7 816 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 140 152 - T 10-11-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 A4G23_RS15515 10b3653696861f16676d6358ab4138b7 816 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 28 50 - T 10-11-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 A4G23_RS15515 10b3653696861f16676d6358ab4138b7 816 SUPERFAMILY SSF50998 498 815 1.96E-27 T 10-11-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily A4G23_RS22790 da6c41fb50ba20510c22678c8f69f383 353 SUPERFAMILY SSF51905 234 346 9.71E-12 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS22790 da6c41fb50ba20510c22678c8f69f383 353 SUPERFAMILY SSF51905 166 202 9.71E-12 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS22790 da6c41fb50ba20510c22678c8f69f383 353 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 6 28 4.0E-15 T 10-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4G23_RS22790 da6c41fb50ba20510c22678c8f69f383 353 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 123 131 4.0E-15 T 10-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4G23_RS22790 da6c41fb50ba20510c22678c8f69f383 353 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 162 186 4.0E-15 T 10-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4G23_RS22790 da6c41fb50ba20510c22678c8f69f383 353 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 166 184 9.1E-12 T 10-11-2016 A4G23_RS22790 da6c41fb50ba20510c22678c8f69f383 353 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 9.1E-12 T 10-11-2016 A4G23_RS22790 da6c41fb50ba20510c22678c8f69f383 353 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 275 291 9.1E-12 T 10-11-2016 A4G23_RS22790 da6c41fb50ba20510c22678c8f69f383 353 Gene3D G3DSA:3.50.50.60 4 143 8.5E-29 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS22790 da6c41fb50ba20510c22678c8f69f383 353 Gene3D G3DSA:3.50.50.60 274 346 1.1E-6 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS22790 da6c41fb50ba20510c22678c8f69f383 353 Gene3D G3DSA:3.50.50.60 144 202 7.4E-23 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS22790 da6c41fb50ba20510c22678c8f69f383 353 Gene3D G3DSA:3.50.50.60 249 273 7.4E-23 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS22790 da6c41fb50ba20510c22678c8f69f383 353 SUPERFAMILY SSF51905 1 199 1.94E-42 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS22790 da6c41fb50ba20510c22678c8f69f383 353 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 8 197 5.9E-28 T 10-11-2016 A4G23_RS10830 369c5f5b813a65cfaff303b5e0dc87a5 206 Pfam PF08281 Sigma-70, region 4 136 188 4.9E-16 T 10-11-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS10830 369c5f5b813a65cfaff303b5e0dc87a5 206 SUPERFAMILY SSF88946 23 117 9.02E-24 T 10-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS10830 369c5f5b813a65cfaff303b5e0dc87a5 206 Pfam PF04542 Sigma-70 region 2 36 105 1.3E-16 T 10-11-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS10830 369c5f5b813a65cfaff303b5e0dc87a5 206 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 31 190 2.3E-27 T 10-11-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS10830 369c5f5b813a65cfaff303b5e0dc87a5 206 Gene3D G3DSA:1.10.10.10 130 192 2.3E-19 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS10830 369c5f5b813a65cfaff303b5e0dc87a5 206 SUPERFAMILY SSF88659 129 191 1.55E-15 T 10-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS10830 369c5f5b813a65cfaff303b5e0dc87a5 206 Gene3D G3DSA:1.10.1740.10 22 123 2.5E-28 T 10-11-2016 A4G23_RS21600 54795ced14beae95e93ee0d394618693 332 SUPERFAMILY SSF55961 112 331 3.85E-27 T 10-11-2016 A4G23_RS21600 54795ced14beae95e93ee0d394618693 332 SUPERFAMILY SSF50022 10 128 4.19E-31 T 10-11-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A4G23_RS21600 54795ced14beae95e93ee0d394618693 332 Gene3D G3DSA:2.102.10.10 13 128 1.5E-24 T 10-11-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A4G23_RS21600 54795ced14beae95e93ee0d394618693 332 Pfam PF00355 Rieske [2Fe-2S] domain 15 104 4.6E-17 T 10-11-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A4G23_RS24055 3e3b6aba33dc1c5d2e104f3ae2a0c5aa 428 SUPERFAMILY SSF53474 8 255 1.49E-51 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS24055 3e3b6aba33dc1c5d2e104f3ae2a0c5aa 428 PRINTS PR00111 Alpha/beta hydrolase fold signature 45 60 1.8E-5 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS24055 3e3b6aba33dc1c5d2e104f3ae2a0c5aa 428 PRINTS PR00111 Alpha/beta hydrolase fold signature 102 115 1.8E-5 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS24055 3e3b6aba33dc1c5d2e104f3ae2a0c5aa 428 PRINTS PR00111 Alpha/beta hydrolase fold signature 201 215 1.8E-5 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS24055 3e3b6aba33dc1c5d2e104f3ae2a0c5aa 428 SUPERFAMILY SSF69118 304 422 3.27E-33 T 10-11-2016 IPR029032 AhpD-like Reactome: R-HSA-5628897 A4G23_RS24055 3e3b6aba33dc1c5d2e104f3ae2a0c5aa 428 Gene3D G3DSA:1.20.1290.10 321 423 4.7E-26 T 10-11-2016 IPR029032 AhpD-like Reactome: R-HSA-5628897 A4G23_RS24055 3e3b6aba33dc1c5d2e104f3ae2a0c5aa 428 Gene3D G3DSA:3.40.50.1820 8 256 2.0E-50 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS24055 3e3b6aba33dc1c5d2e104f3ae2a0c5aa 428 Pfam PF02627 Carboxymuconolactone decarboxylase family 335 417 9.0E-25 T 10-11-2016 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A4G23_RS24055 3e3b6aba33dc1c5d2e104f3ae2a0c5aa 428 Pfam PF00561 alpha/beta hydrolase fold 20 122 1.1E-7 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS21400 e19cb17944ed50fadd7960e1a5eb361d 705 Pfam PF00204 DNA gyrase B 258 450 3.3E-55 T 10-11-2016 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4G23_RS21400 e19cb17944ed50fadd7960e1a5eb361d 705 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 634 691 7.8E-25 T 10-11-2016 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4G23_RS21400 e19cb17944ed50fadd7960e1a5eb361d 705 Gene3D G3DSA:3.40.50.670 464 684 2.4E-73 T 10-11-2016 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4G23_RS21400 e19cb17944ed50fadd7960e1a5eb361d 705 SUPERFAMILY SSF56719 454 695 1.23E-74 T 10-11-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 A4G23_RS21400 e19cb17944ed50fadd7960e1a5eb361d 705 Pfam PF01751 Toprim domain 479 586 6.2E-15 T 10-11-2016 IPR006171 Toprim domain A4G23_RS21400 e19cb17944ed50fadd7960e1a5eb361d 705 ProSitePatterns PS00177 DNA topoisomerase II signature. 482 490 - T 10-11-2016 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4G23_RS21400 e19cb17944ed50fadd7960e1a5eb361d 705 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 47 171 1.4E-21 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS21400 e19cb17944ed50fadd7960e1a5eb361d 705 Gene3D G3DSA:3.30.230.10 257 450 2.4E-49 T 10-11-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A4G23_RS21400 e19cb17944ed50fadd7960e1a5eb361d 705 PRINTS PR01159 DNA gyrase subunit B signature 228 241 3.0E-35 T 10-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4G23_RS21400 e19cb17944ed50fadd7960e1a5eb361d 705 PRINTS PR01159 DNA gyrase subunit B signature 530 539 3.0E-35 T 10-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4G23_RS21400 e19cb17944ed50fadd7960e1a5eb361d 705 PRINTS PR01159 DNA gyrase subunit B signature 656 668 3.0E-35 T 10-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4G23_RS21400 e19cb17944ed50fadd7960e1a5eb361d 705 PRINTS PR01159 DNA gyrase subunit B signature 257 279 3.0E-35 T 10-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4G23_RS21400 e19cb17944ed50fadd7960e1a5eb361d 705 PRINTS PR01159 DNA gyrase subunit B signature 368 384 3.0E-35 T 10-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4G23_RS21400 e19cb17944ed50fadd7960e1a5eb361d 705 PRINTS PR01159 DNA gyrase subunit B signature 213 228 3.0E-35 T 10-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4G23_RS21400 e19cb17944ed50fadd7960e1a5eb361d 705 PRINTS PR01159 DNA gyrase subunit B signature 434 454 3.0E-35 T 10-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4G23_RS21400 e19cb17944ed50fadd7960e1a5eb361d 705 PRINTS PR01159 DNA gyrase subunit B signature 22 32 3.0E-35 T 10-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4G23_RS21400 e19cb17944ed50fadd7960e1a5eb361d 705 PRINTS PR01159 DNA gyrase subunit B signature 672 688 3.0E-35 T 10-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4G23_RS21400 e19cb17944ed50fadd7960e1a5eb361d 705 SUPERFAMILY SSF54211 258 450 4.17E-39 T 10-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold A4G23_RS21400 e19cb17944ed50fadd7960e1a5eb361d 705 SMART SM00433 51 696 4.8E-282 T 10-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4G23_RS21400 e19cb17944ed50fadd7960e1a5eb361d 705 SMART SM00387 47 207 5.1E-23 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS21400 e19cb17944ed50fadd7960e1a5eb361d 705 SUPERFAMILY SSF55874 22 241 1.02E-59 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS21400 e19cb17944ed50fadd7960e1a5eb361d 705 Gene3D G3DSA:3.30.565.10 22 242 1.7E-82 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS21400 e19cb17944ed50fadd7960e1a5eb361d 705 PRINTS PR00418 DNA topoisomerase II family signature 324 337 4.0E-59 T 10-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4G23_RS21400 e19cb17944ed50fadd7960e1a5eb361d 705 PRINTS PR00418 DNA topoisomerase II family signature 584 596 4.0E-59 T 10-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4G23_RS21400 e19cb17944ed50fadd7960e1a5eb361d 705 PRINTS PR00418 DNA topoisomerase II family signature 564 581 4.0E-59 T 10-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4G23_RS21400 e19cb17944ed50fadd7960e1a5eb361d 705 PRINTS PR00418 DNA topoisomerase II family signature 635 651 4.0E-59 T 10-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4G23_RS21400 e19cb17944ed50fadd7960e1a5eb361d 705 PRINTS PR00418 DNA topoisomerase II family signature 480 494 4.0E-59 T 10-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4G23_RS21400 e19cb17944ed50fadd7960e1a5eb361d 705 PRINTS PR00418 DNA topoisomerase II family signature 129 143 4.0E-59 T 10-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4G23_RS21400 e19cb17944ed50fadd7960e1a5eb361d 705 PRINTS PR00418 DNA topoisomerase II family signature 546 562 4.0E-59 T 10-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4G23_RS21400 e19cb17944ed50fadd7960e1a5eb361d 705 PRINTS PR00418 DNA topoisomerase II family signature 51 66 4.0E-59 T 10-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4G23_RS21400 e19cb17944ed50fadd7960e1a5eb361d 705 PRINTS PR00418 DNA topoisomerase II family signature 86 99 4.0E-59 T 10-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4G23_RS25135 a499187c0c53beb8e292fe502c5856a4 143 Gene3D G3DSA:3.30.450.30 10 128 2.2E-21 T 10-11-2016 A4G23_RS25135 a499187c0c53beb8e292fe502c5856a4 143 Pfam PF03259 Roadblock/LC7 domain 13 104 9.5E-25 T 10-11-2016 IPR004942 Roadblock/LAMTOR2 domain A4G23_RS25135 a499187c0c53beb8e292fe502c5856a4 143 SMART SM00960 14 104 2.3E-26 T 10-11-2016 IPR004942 Roadblock/LAMTOR2 domain A4G23_RS25135 a499187c0c53beb8e292fe502c5856a4 143 SUPERFAMILY SSF103196 9 130 1.19E-24 T 10-11-2016 A4G23_RS15470 402cd407fd2bce9f11de0714fe753086 230 Gene3D G3DSA:1.20.144.10 13 170 1.9E-30 T 10-11-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A4G23_RS15470 402cd407fd2bce9f11de0714fe753086 230 SMART SM00014 54 168 2.3E-13 T 10-11-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A4G23_RS15470 402cd407fd2bce9f11de0714fe753086 230 Pfam PF01569 PAP2 superfamily 62 171 6.4E-19 T 10-11-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A4G23_RS15470 402cd407fd2bce9f11de0714fe753086 230 SUPERFAMILY SSF48317 14 173 6.02E-31 T 10-11-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A4G23_RS19350 219789af50963032138ffddf03225a32 370 Pfam PF11583 P-aminobenzoate N-oxygenase AurF 36 305 8.8E-10 T 10-11-2016 IPR025859 P-aminobenzoate N-oxygenase AurF A4G23_RS19350 219789af50963032138ffddf03225a32 370 Gene3D G3DSA:1.10.620.20 36 254 3.1E-18 T 10-11-2016 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: R-HSA-499943 A4G23_RS19350 219789af50963032138ffddf03225a32 370 SUPERFAMILY SSF47240 89 318 2.05E-69 T 10-11-2016 IPR009078 Ferritin-like superfamily A4G23_RS14135 7f7b1407aa8dd98f7270ff02eee84521 208 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 70 142 9.1E-14 T 10-11-2016 IPR000772 Ricin B, lectin domain A4G23_RS14135 7f7b1407aa8dd98f7270ff02eee84521 208 Gene3D G3DSA:2.80.10.50 74 196 3.0E-18 T 10-11-2016 A4G23_RS14135 7f7b1407aa8dd98f7270ff02eee84521 208 SMART SM00458 71 206 4.8E-5 T 10-11-2016 IPR000772 Ricin B, lectin domain A4G23_RS14135 7f7b1407aa8dd98f7270ff02eee84521 208 SUPERFAMILY SSF50370 68 195 3.15E-27 T 10-11-2016 IPR000772 Ricin B, lectin domain A4G23_RS22205 b866d6b58d8c00a453b6701c18867019 197 Pfam PF11127 Protein of unknown function (DUF2892) 122 175 1.1E-8 T 10-11-2016 IPR021309 Protein of unknown function DUF2892 A4G23_RS22205 b866d6b58d8c00a453b6701c18867019 197 Gene3D G3DSA:3.40.250.10 11 117 7.8E-30 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS22205 b866d6b58d8c00a453b6701c18867019 197 SUPERFAMILY SSF52821 9 116 4.85E-33 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS22205 b866d6b58d8c00a453b6701c18867019 197 SMART SM00450 15 112 3.4E-26 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS22205 b866d6b58d8c00a453b6701c18867019 197 Pfam PF00581 Rhodanese-like domain 16 108 3.0E-17 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS09780 4a91c7f0b48fa3ec4d92448d8785e734 186 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 54 2.9E-10 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS09780 4a91c7f0b48fa3ec4d92448d8785e734 186 Pfam PF16859 Bacterial transcriptional repressor C-terminal 68 179 5.8E-27 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS09780 4a91c7f0b48fa3ec4d92448d8785e734 186 SUPERFAMILY SSF48498 68 185 3.39E-22 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS09780 4a91c7f0b48fa3ec4d92448d8785e734 186 Gene3D G3DSA:1.10.10.60 4 48 1.3E-19 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS09780 4a91c7f0b48fa3ec4d92448d8785e734 186 Gene3D G3DSA:1.10.357.10 50 186 1.3E-34 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS09780 4a91c7f0b48fa3ec4d92448d8785e734 186 ProSitePatterns PS01081 TetR-type HTH domain signature. 22 53 - T 10-11-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A4G23_RS09780 4a91c7f0b48fa3ec4d92448d8785e734 186 SUPERFAMILY SSF46689 5 60 1.7E-11 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS21845 f441c32318199205d950a6148dd3f604 89 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 3 54 4.5E-13 T 10-11-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM A4G23_RS21845 f441c32318199205d950a6148dd3f604 89 Gene3D G3DSA:3.40.1620.10 4 49 2.2E-19 T 10-11-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM A4G23_RS21845 f441c32318199205d950a6148dd3f604 89 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 4 66 1.0E-15 T 10-11-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM A4G23_RS21845 f441c32318199205d950a6148dd3f604 89 SUPERFAMILY SSF143120 4 60 1.44E-13 T 10-11-2016 A4G23_RS22015 ef4134ebe7dbccca5ce6818ad01830ec 472 PRINTS PR00131 Glycosyl hydrolase family 1 signature 375 383 3.6E-21 T 10-11-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A4G23_RS22015 ef4134ebe7dbccca5ce6818ad01830ec 472 PRINTS PR00131 Glycosyl hydrolase family 1 signature 396 407 3.6E-21 T 10-11-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A4G23_RS22015 ef4134ebe7dbccca5ce6818ad01830ec 472 PRINTS PR00131 Glycosyl hydrolase family 1 signature 441 453 3.6E-21 T 10-11-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A4G23_RS22015 ef4134ebe7dbccca5ce6818ad01830ec 472 PRINTS PR00131 Glycosyl hydrolase family 1 signature 306 320 3.6E-21 T 10-11-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A4G23_RS22015 ef4134ebe7dbccca5ce6818ad01830ec 472 PRINTS PR00131 Glycosyl hydrolase family 1 signature 417 434 3.6E-21 T 10-11-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A4G23_RS22015 ef4134ebe7dbccca5ce6818ad01830ec 472 Gene3D G3DSA:3.20.20.80 23 471 2.2E-158 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS22015 ef4134ebe7dbccca5ce6818ad01830ec 472 Pfam PF00232 Glycosyl hydrolase family 1 23 471 9.8E-159 T 10-11-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A4G23_RS22015 ef4134ebe7dbccca5ce6818ad01830ec 472 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 28 42 - T 10-11-2016 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site A4G23_RS22015 ef4134ebe7dbccca5ce6818ad01830ec 472 TIGRFAM TIGR03356 BGL: beta-galactosidase 24 463 2.2E-183 T 10-11-2016 IPR017736 Glycoside hydrolase, family 1, beta-glucosidase GO:0008422|GO:0030245 KEGG: 00460+3.2.1.21|KEGG: 00500+3.2.1.21|KEGG: 00940+3.2.1.21|MetaCyc: PWY-3121|MetaCyc: PWY-5176|MetaCyc: PWY-6002|MetaCyc: PWY-6788|MetaCyc: PWY-7089|MetaCyc: PWY-7091|MetaCyc: PWY-7092 A4G23_RS22015 ef4134ebe7dbccca5ce6818ad01830ec 472 SUPERFAMILY SSF51445 23 471 6.85E-157 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS22015 ef4134ebe7dbccca5ce6818ad01830ec 472 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 375 383 - T 10-11-2016 IPR018120 Glycoside hydrolase family 1, active site A4G23_RS12240 3ddce04769ac5ff6bcfa2c548eee47d8 253 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 5 234 42.129 T 10-11-2016 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 A4G23_RS12240 3ddce04769ac5ff6bcfa2c548eee47d8 253 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 8 126 3.5E-25 T 10-11-2016 IPR013078 Histidine phosphatase superfamily, clade-1 A4G23_RS12240 3ddce04769ac5ff6bcfa2c548eee47d8 253 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 10 19 - T 10-11-2016 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 A4G23_RS12240 3ddce04769ac5ff6bcfa2c548eee47d8 253 SMART SM00855 7 193 1.9E-22 T 10-11-2016 IPR013078 Histidine phosphatase superfamily, clade-1 A4G23_RS12240 3ddce04769ac5ff6bcfa2c548eee47d8 253 Gene3D G3DSA:3.40.50.1240 5 253 8.0E-87 T 10-11-2016 IPR029033 Histidine phosphatase superfamily A4G23_RS12240 3ddce04769ac5ff6bcfa2c548eee47d8 253 SUPERFAMILY SSF53254 6 227 5.69E-70 T 10-11-2016 IPR029033 Histidine phosphatase superfamily A4G23_RS12240 3ddce04769ac5ff6bcfa2c548eee47d8 253 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 7 251 3.2E-110 T 10-11-2016 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 A4G23_RS25835 2c37e408f37957043408548c8e9ff65b 207 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 90 192 1.0E-6 T 10-11-2016 IPR000701 Succinate dehydrogenase/Fumarate reductase, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4G23_RS25835 2c37e408f37957043408548c8e9ff65b 207 SUPERFAMILY SSF81343 1 206 7.33E-47 T 10-11-2016 A4G23_RS25835 2c37e408f37957043408548c8e9ff65b 207 Gene3D G3DSA:1.20.950.10 3 203 7.3E-11 T 10-11-2016 A4G23_RS25835 2c37e408f37957043408548c8e9ff65b 207 TIGRFAM TIGR02046 sdhC_b558_fam: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family 1 206 2.8E-66 T 10-11-2016 IPR011138 Succinate dehydrogenase cytochrome b558 subunit A4G23_RS06915 db2969e93e04af555ab3babe199f2a88 139 SUPERFAMILY SSF54631 2 131 5.05E-33 T 10-11-2016 A4G23_RS06915 db2969e93e04af555ab3babe199f2a88 139 SMART SM00116 11 59 1.9E-5 T 10-11-2016 IPR000644 CBS domain A4G23_RS06915 db2969e93e04af555ab3babe199f2a88 139 SMART SM00116 77 124 5.9E-7 T 10-11-2016 IPR000644 CBS domain A4G23_RS06915 db2969e93e04af555ab3babe199f2a88 139 Gene3D G3DSA:3.10.580.10 2 121 3.1E-33 T 10-11-2016 A4G23_RS06915 db2969e93e04af555ab3babe199f2a88 139 Pfam PF00571 CBS domain 82 124 6.0E-10 T 10-11-2016 IPR000644 CBS domain A4G23_RS06915 db2969e93e04af555ab3babe199f2a88 139 Pfam PF00571 CBS domain 4 55 2.0E-12 T 10-11-2016 IPR000644 CBS domain A4G23_RS10920 cb0806adee5bf797fae366efaad92ef1 441 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 271 434 8.9E-39 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS10920 cb0806adee5bf797fae366efaad92ef1 441 Pfam PF01590 GAF domain 114 212 3.5E-13 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS10920 cb0806adee5bf797fae366efaad92ef1 441 Gene3D G3DSA:3.30.450.40 39 221 2.4E-33 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS10920 cb0806adee5bf797fae366efaad92ef1 441 SUPERFAMILY SSF81606 259 403 8.37E-6 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS10920 cb0806adee5bf797fae366efaad92ef1 441 SMART SM00065 15 224 1.5E-10 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS10920 cb0806adee5bf797fae366efaad92ef1 441 SMART SM00331 245 441 5.3E-37 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS10920 cb0806adee5bf797fae366efaad92ef1 441 SUPERFAMILY SSF55781 109 219 1.81E-16 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS26330 acd39f7eb53f1901d15fe1c6357518d3 500 Gene3D G3DSA:2.30.38.10 317 391 1.4E-22 T 10-11-2016 A4G23_RS26330 acd39f7eb53f1901d15fe1c6357518d3 500 Gene3D G3DSA:3.30.300.30 399 498 2.7E-26 T 10-11-2016 A4G23_RS26330 acd39f7eb53f1901d15fe1c6357518d3 500 Gene3D G3DSA:3.40.50.980 3 156 1.3E-29 T 10-11-2016 A4G23_RS26330 acd39f7eb53f1901d15fe1c6357518d3 500 Pfam PF00501 AMP-binding enzyme 10 405 3.5E-71 T 10-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A4G23_RS26330 acd39f7eb53f1901d15fe1c6357518d3 500 SUPERFAMILY SSF56801 3 498 8.37E-118 T 10-11-2016 A4G23_RS26330 acd39f7eb53f1901d15fe1c6357518d3 500 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 29 429 3.6E-103 T 10-11-2016 IPR010071 Amino acid adenylation domain A4G23_RS26330 acd39f7eb53f1901d15fe1c6357518d3 500 Gene3D G3DSA:3.40.50.980 157 309 3.5E-32 T 10-11-2016 A4G23_RS26330 acd39f7eb53f1901d15fe1c6357518d3 500 Pfam PF13193 AMP-binding enzyme C-terminal domain 413 487 2.3E-11 T 10-11-2016 IPR025110 AMP-binding enzyme C-terminal domain A4G23_RS12940 292c462d6c004015a9d34d418d392e40 202 SMART SM00448 3 116 3.1E-25 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS12940 292c462d6c004015a9d34d418d392e40 202 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 142 156 3.3E-9 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS12940 292c462d6c004015a9d34d418d392e40 202 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 172 3.3E-9 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS12940 292c462d6c004015a9d34d418d392e40 202 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 184 3.3E-9 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS12940 292c462d6c004015a9d34d418d392e40 202 Gene3D G3DSA:3.40.50.2300 3 145 1.0E-35 T 10-11-2016 A4G23_RS12940 292c462d6c004015a9d34d418d392e40 202 SUPERFAMILY SSF52172 3 130 1.02E-30 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS12940 292c462d6c004015a9d34d418d392e40 202 Pfam PF00072 Response regulator receiver domain 5 116 3.7E-25 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS12940 292c462d6c004015a9d34d418d392e40 202 SUPERFAMILY SSF46894 129 202 9.52E-19 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS12940 292c462d6c004015a9d34d418d392e40 202 Gene3D G3DSA:1.10.10.10 146 202 9.1E-21 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS12940 292c462d6c004015a9d34d418d392e40 202 SMART SM00421 139 196 3.4E-19 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS12940 292c462d6c004015a9d34d418d392e40 202 Pfam PF00196 Bacterial regulatory proteins, luxR family 141 196 1.5E-15 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS10380 3341b23c122cb4cb76e8797db244a759 162 Pfam PF04977 Septum formation initiator 46 123 8.0E-15 T 10-11-2016 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 A4G23_RS21465 7645d094bbb793b892f64d550b2313ac 287 SUPERFAMILY SSF52821 159 284 3.14E-30 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS21465 7645d094bbb793b892f64d550b2313ac 287 SMART SM00450 160 278 6.3E-10 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS21465 7645d094bbb793b892f64d550b2313ac 287 SMART SM00450 18 142 7.5E-24 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS21465 7645d094bbb793b892f64d550b2313ac 287 ProSitePatterns PS00683 Rhodanese C-terminal signature. 262 272 - T 10-11-2016 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 A4G23_RS21465 7645d094bbb793b892f64d550b2313ac 287 SUPERFAMILY SSF52821 7 153 3.93E-35 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS21465 7645d094bbb793b892f64d550b2313ac 287 ProSitePatterns PS00380 Rhodanese signature 1. 50 61 - T 10-11-2016 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 A4G23_RS21465 7645d094bbb793b892f64d550b2313ac 287 Gene3D G3DSA:3.40.250.10 3 154 1.3E-44 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS21465 7645d094bbb793b892f64d550b2313ac 287 Gene3D G3DSA:3.40.250.10 159 284 2.2E-36 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS21465 7645d094bbb793b892f64d550b2313ac 287 Pfam PF00581 Rhodanese-like domain 21 137 6.3E-18 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS21465 7645d094bbb793b892f64d550b2313ac 287 Pfam PF00581 Rhodanese-like domain 172 274 4.3E-10 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS17295 ade22327dd7822dac92a99fe68fbaabb 479 Pfam PF00392 Bacterial regulatory proteins, gntR family 31 88 1.3E-17 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS17295 ade22327dd7822dac92a99fe68fbaabb 479 SMART SM00345 29 88 2.9E-17 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS17295 ade22327dd7822dac92a99fe68fbaabb 479 Gene3D G3DSA:3.40.640.10 149 370 3.5E-49 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS17295 ade22327dd7822dac92a99fe68fbaabb 479 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 62 2.1E-6 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS17295 ade22327dd7822dac92a99fe68fbaabb 479 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 62 78 2.1E-6 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS17295 ade22327dd7822dac92a99fe68fbaabb 479 Gene3D G3DSA:1.10.10.10 30 93 1.3E-23 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS17295 ade22327dd7822dac92a99fe68fbaabb 479 Pfam PF00155 Aminotransferase class I and II 135 429 1.9E-18 T 10-11-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4G23_RS17295 ade22327dd7822dac92a99fe68fbaabb 479 SUPERFAMILY SSF53383 108 478 5.89E-79 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS17295 ade22327dd7822dac92a99fe68fbaabb 479 SUPERFAMILY SSF46785 28 98 3.63E-19 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS07845 725aa19a96ecaaa0d84c4ba8abbd9be3 589 Gene3D G3DSA:3.20.20.70 32 426 2.2E-142 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS07845 725aa19a96ecaaa0d84c4ba8abbd9be3 589 SUPERFAMILY SSF89000 421 470 3.69E-15 T 10-11-2016 A4G23_RS07845 725aa19a96ecaaa0d84c4ba8abbd9be3 589 TIGRFAM TIGR00970 leuA_yeast: 2-isopropylmalate synthase 28 589 6.2E-255 T 10-11-2016 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A4G23_RS07845 725aa19a96ecaaa0d84c4ba8abbd9be3 589 Pfam PF08502 LeuA allosteric (dimerisation) domain 455 586 1.2E-36 T 10-11-2016 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A4G23_RS07845 725aa19a96ecaaa0d84c4ba8abbd9be3 589 Hamap MF_00572 2-isopropylmalate synthase [leuA]. 29 589 54.207 T 10-11-2016 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A4G23_RS07845 725aa19a96ecaaa0d84c4ba8abbd9be3 589 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 266 279 - T 10-11-2016 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A4G23_RS07845 725aa19a96ecaaa0d84c4ba8abbd9be3 589 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 61 77 - T 10-11-2016 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A4G23_RS07845 725aa19a96ecaaa0d84c4ba8abbd9be3 589 Pfam PF00682 HMGL-like 54 334 6.8E-73 T 10-11-2016 IPR000891 Pyruvate carboxyltransferase GO:0003824 A4G23_RS07845 725aa19a96ecaaa0d84c4ba8abbd9be3 589 SMART SM00917 455 588 2.8E-39 T 10-11-2016 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A4G23_RS07845 725aa19a96ecaaa0d84c4ba8abbd9be3 589 SUPERFAMILY SSF51569 43 353 6.96E-94 T 10-11-2016 A4G23_RS07845 725aa19a96ecaaa0d84c4ba8abbd9be3 589 SUPERFAMILY SSF110921 485 586 1.44E-35 T 10-11-2016 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A4G23_RS26490 109155af9bd0796b411f9600fc246a85 233 Gene3D G3DSA:2.40.50.230 25 91 1.4E-21 T 10-11-2016 IPR006531 Gp5 N-terminal A4G23_RS26490 109155af9bd0796b411f9600fc246a85 233 SUPERFAMILY SSF69255 15 92 5.75E-21 T 10-11-2016 A4G23_RS00880 741cf0fe99057f7dff534ad95fe5d1cf 190 SMART SM01120 21 187 3.9E-67 T 10-11-2016 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 A4G23_RS00880 741cf0fe99057f7dff534ad95fe5d1cf 190 TIGRFAM TIGR02365 dha_L_ycgS: dihydroxyacetone kinase, L subunit 3 186 1.8E-63 T 10-11-2016 IPR012737 Dihydroxyacetone kinase, subunit L GO:0016772 A4G23_RS00880 741cf0fe99057f7dff534ad95fe5d1cf 190 Pfam PF02734 DAK2 domain 21 186 2.0E-50 T 10-11-2016 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 A4G23_RS00880 741cf0fe99057f7dff534ad95fe5d1cf 190 SUPERFAMILY SSF101473 6 188 2.62E-49 T 10-11-2016 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 A4G23_RS23365 75517e61885eeb1b55fbc2891efc9aaf 301 SUPERFAMILY SSF103481 182 284 2.35E-16 T 10-11-2016 A4G23_RS23365 75517e61885eeb1b55fbc2891efc9aaf 301 Pfam PF00892 EamA-like transporter family 147 280 1.2E-20 T 10-11-2016 IPR000620 EamA domain GO:0016020|GO:0016021 A4G23_RS23365 75517e61885eeb1b55fbc2891efc9aaf 301 Pfam PF00892 EamA-like transporter family 12 136 1.5E-13 T 10-11-2016 IPR000620 EamA domain GO:0016020|GO:0016021 A4G23_RS23365 75517e61885eeb1b55fbc2891efc9aaf 301 SUPERFAMILY SSF103481 49 139 4.97E-16 T 10-11-2016 A4G23_RS24225 d9fa33811856c83e09e8679a18f3ef70 164 SUPERFAMILY SSF46767 75 156 3.4E-33 T 10-11-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A4G23_RS24225 d9fa33811856c83e09e8679a18f3ef70 164 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 3 158 39.017 T 10-11-2016 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 A4G23_RS24225 d9fa33811856c83e09e8679a18f3ef70 164 SUPERFAMILY SSF53155 4 81 1.47E-17 T 10-11-2016 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A4G23_RS24225 d9fa33811856c83e09e8679a18f3ef70 164 Gene3D G3DSA:1.10.10.10 75 156 5.6E-36 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS24225 d9fa33811856c83e09e8679a18f3ef70 164 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 77 155 4.8E-34 T 10-11-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A4G23_RS24225 d9fa33811856c83e09e8679a18f3ef70 164 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 76 155 3.5E-35 T 10-11-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A4G23_RS24225 d9fa33811856c83e09e8679a18f3ef70 164 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 126 132 - T 10-11-2016 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A4G23_RS21340 7c1d03abc173ba7e0f17649b824a4852 720 Pfam PF16124 RecQ zinc-binding 440 486 1.3E-5 T 10-11-2016 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain A4G23_RS21340 7c1d03abc173ba7e0f17649b824a4852 720 ProSitePatterns PS00690 DEAH-box subfamily ATP-dependent helicases signature. 149 158 - T 10-11-2016 IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site GO:0003676|GO:0005524|GO:0008026 A4G23_RS21340 7c1d03abc173ba7e0f17649b824a4852 720 SMART SM00487 23 224 1.4E-22 T 10-11-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4G23_RS21340 7c1d03abc173ba7e0f17649b824a4852 720 Gene3D G3DSA:3.40.50.2020 603 718 4.5E-7 T 10-11-2016 IPR029057 Phosphoribosyltransferase-like A4G23_RS21340 7c1d03abc173ba7e0f17649b824a4852 720 Pfam PF00270 DEAD/DEAH box helicase 30 196 7.4E-15 T 10-11-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A4G23_RS21340 7c1d03abc173ba7e0f17649b824a4852 720 Gene3D G3DSA:1.10.10.10 436 499 5.6E-10 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS21340 7c1d03abc173ba7e0f17649b824a4852 720 Gene3D G3DSA:3.40.50.300 218 368 3.8E-28 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS21340 7c1d03abc173ba7e0f17649b824a4852 720 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 24 359 5.9E-67 T 10-11-2016 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 A4G23_RS21340 7c1d03abc173ba7e0f17649b824a4852 720 Gene3D G3DSA:3.40.50.300 23 206 4.0E-35 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS21340 7c1d03abc173ba7e0f17649b824a4852 720 Pfam PF00271 Helicase conserved C-terminal domain 247 343 5.3E-13 T 10-11-2016 IPR001650 Helicase, C-terminal A4G23_RS21340 7c1d03abc173ba7e0f17649b824a4852 720 SMART SM00490 263 344 1.8E-20 T 10-11-2016 IPR001650 Helicase, C-terminal A4G23_RS21340 7c1d03abc173ba7e0f17649b824a4852 720 SUPERFAMILY SSF53271 622 717 1.02E-6 T 10-11-2016 IPR029057 Phosphoribosyltransferase-like A4G23_RS21340 7c1d03abc173ba7e0f17649b824a4852 720 SUPERFAMILY SSF52540 37 353 3.8E-49 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS15755 9ddcb2957798e60641444a49a53c4cfd 415 SUPERFAMILY SSF56112 15 280 7.01E-78 T 10-11-2016 IPR011009 Protein kinase-like domain A4G23_RS15755 9ddcb2957798e60641444a49a53c4cfd 415 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 145 157 - T 10-11-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 A4G23_RS15755 9ddcb2957798e60641444a49a53c4cfd 415 Gene3D G3DSA:1.10.510.10 124 282 2.9E-47 T 10-11-2016 A4G23_RS15755 9ddcb2957798e60641444a49a53c4cfd 415 Gene3D G3DSA:3.30.200.20 15 123 7.0E-25 T 10-11-2016 A4G23_RS15755 9ddcb2957798e60641444a49a53c4cfd 415 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 25 48 - T 10-11-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 A4G23_RS15755 9ddcb2957798e60641444a49a53c4cfd 415 SMART SM00220 19 287 7.9E-66 T 10-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4G23_RS15755 9ddcb2957798e60641444a49a53c4cfd 415 Pfam PF00069 Protein kinase domain 19 240 1.5E-48 T 10-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4G23_RS00640 f37edfc93dda70f9ec68bc4c7ca9235a 533 SUPERFAMILY SSF51971 324 385 2.24E-36 T 10-11-2016 A4G23_RS00640 f37edfc93dda70f9ec68bc4c7ca9235a 533 SUPERFAMILY SSF51971 29 272 2.24E-36 T 10-11-2016 A4G23_RS00640 f37edfc93dda70f9ec68bc4c7ca9235a 533 Gene3D G3DSA:3.50.50.60 339 396 3.4E-45 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS00640 f37edfc93dda70f9ec68bc4c7ca9235a 533 Gene3D G3DSA:3.50.50.60 19 119 3.4E-45 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS00640 f37edfc93dda70f9ec68bc4c7ca9235a 533 Gene3D G3DSA:3.50.50.60 167 246 3.4E-45 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS00640 f37edfc93dda70f9ec68bc4c7ca9235a 533 Gene3D G3DSA:2.102.10.10 421 512 9.5E-31 T 10-11-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A4G23_RS00640 f37edfc93dda70f9ec68bc4c7ca9235a 533 Pfam PF00355 Rieske [2Fe-2S] domain 426 505 2.5E-16 T 10-11-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A4G23_RS00640 f37edfc93dda70f9ec68bc4c7ca9235a 533 Pfam PF01266 FAD dependent oxidoreductase 31 378 1.1E-46 T 10-11-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A4G23_RS00640 f37edfc93dda70f9ec68bc4c7ca9235a 533 PRINTS PR00162 Rieske 2Fe-2S subunit signature 480 492 6.3E-11 T 10-11-2016 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 A4G23_RS00640 f37edfc93dda70f9ec68bc4c7ca9235a 533 PRINTS PR00162 Rieske 2Fe-2S subunit signature 492 504 6.3E-11 T 10-11-2016 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 A4G23_RS00640 f37edfc93dda70f9ec68bc4c7ca9235a 533 PRINTS PR00162 Rieske 2Fe-2S subunit signature 459 470 6.3E-11 T 10-11-2016 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 A4G23_RS00640 f37edfc93dda70f9ec68bc4c7ca9235a 533 SUPERFAMILY SSF50022 424 519 5.37E-28 T 10-11-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A4G23_RS24430 4af3b7d3bfe42695f93bedc3782b9378 120 Pfam PF11387 Protein of unknown function (DUF2795) 69 113 1.9E-13 T 10-11-2016 IPR021527 Protein of unknown function DUF2795 A4G23_RS27090 e6a96e0bd733541a8c79e1f363e9aefa 349 SUPERFAMILY SSF109854 2 129 3.3E-6 T 10-11-2016 A4G23_RS27090 e6a96e0bd733541a8c79e1f363e9aefa 349 Pfam PF13302 Acetyltransferase (GNAT) domain 235 329 2.7E-20 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS27090 e6a96e0bd733541a8c79e1f363e9aefa 349 Gene3D G3DSA:3.40.630.30 186 340 1.9E-30 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS27090 e6a96e0bd733541a8c79e1f363e9aefa 349 SUPERFAMILY SSF55729 186 332 1.9E-27 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS27090 e6a96e0bd733541a8c79e1f363e9aefa 349 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 3 124 8.0E-7 T 10-11-2016 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 A4G23_RS00375 3fb0e9a4dff61dc8095235d8f326ae37 641 SUPERFAMILY SSF55909 248 511 5.49E-73 T 10-11-2016 A4G23_RS00375 3fb0e9a4dff61dc8095235d8f326ae37 641 SUPERFAMILY SSF55909 557 639 5.49E-73 T 10-11-2016 A4G23_RS00375 3fb0e9a4dff61dc8095235d8f326ae37 641 SUPERFAMILY SSF110083 37 213 1.1E-8 T 10-11-2016 IPR013733 Protein-arginine deiminase (PAD), central domain GO:0004668|GO:0005509|GO:0005737|GO:0018101 MetaCyc: PWY-4921|Reactome: R-HSA-3247509 A4G23_RS00375 3fb0e9a4dff61dc8095235d8f326ae37 641 Pfam PF03068 Protein-arginine deiminase (PAD) 205 640 4.4E-117 T 10-11-2016 IPR013530 Protein-arginine deiminase, C-terminal GO:0004668|GO:0005509|GO:0005737 MetaCyc: PWY-4921|Reactome: R-HSA-3247509 A4G23_RS13805 becdaf85d4d49b47dd14e5308c093b08 179 Pfam PF04314 Protein of unknown function (DUF461) 46 140 5.3E-31 T 10-11-2016 IPR007410 DR1885-like metal-binding protein A4G23_RS13805 becdaf85d4d49b47dd14e5308c093b08 179 SUPERFAMILY SSF110087 36 149 3.92E-36 T 10-11-2016 IPR007410 DR1885-like metal-binding protein A4G23_RS23225 623e3f9b88abca8d8a7190aa660628bd 253 Pfam PF12833 Helix-turn-helix domain 144 216 9.7E-13 T 10-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4G23_RS23225 623e3f9b88abca8d8a7190aa660628bd 253 SMART SM00342 137 219 1.4E-8 T 10-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4G23_RS02485 8360f6d1483d605c999184c0425aaeff 412 SUPERFAMILY SSF53623 47 281 4.06E-29 T 10-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4G23_RS02485 8360f6d1483d605c999184c0425aaeff 412 Gene3D G3DSA:3.40.1190.10 47 284 3.4E-38 T 10-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4G23_RS02485 8360f6d1483d605c999184c0425aaeff 412 Pfam PF08245 Mur ligase middle domain 65 266 1.7E-12 T 10-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4G23_RS02485 8360f6d1483d605c999184c0425aaeff 412 Pfam PF08353 Domain of unknown function (DUF1727) 304 403 1.9E-21 T 10-11-2016 IPR013564 Domain of unknown function DUF1727 A4G23_RS23795 9ce83ce86577ca6c3a14212983ef772d 429 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 4 358 2.6E-23 T 10-11-2016 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 A4G23_RS10985 0f605f65ff41390b2efd7fe600c382b3 437 Gene3D G3DSA:3.40.390.10 205 300 1.4E-7 T 10-11-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 A4G23_RS10985 0f605f65ff41390b2efd7fe600c382b3 437 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 101 365 2.9E-46 T 10-11-2016 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 A4G23_RS10985 0f605f65ff41390b2efd7fe600c382b3 437 SUPERFAMILY SSF55486 203 286 1.69E-5 T 10-11-2016 A4G23_RS10320 923981b9dee107ff2b12e6427e30114a 296 PIRSF PIRSF009160 1 296 3.9E-98 T 10-11-2016 IPR010539 Protein of unknown function UCP009160 A4G23_RS10320 923981b9dee107ff2b12e6427e30114a 296 Pfam PF12811 Bax inhibitor 1 like 5 293 1.4E-80 T 10-11-2016 IPR010539 Protein of unknown function UCP009160 A4G23_RS18940 a11a4dca90bb85a8a28987e57c7f15f3 365 Pfam PF01966 HD domain 188 308 5.9E-19 T 10-11-2016 IPR006674 HD domain A4G23_RS18940 a11a4dca90bb85a8a28987e57c7f15f3 365 Gene3D G3DSA:1.10.3210.10 183 341 2.4E-19 T 10-11-2016 IPR006674 HD domain A4G23_RS18940 a11a4dca90bb85a8a28987e57c7f15f3 365 SMART SM00471 182 317 1.9E-10 T 10-11-2016 IPR003607 HD/PDEase domain A4G23_RS18940 a11a4dca90bb85a8a28987e57c7f15f3 365 SUPERFAMILY SSF109604 172 345 1.46E-35 T 10-11-2016 A4G23_RS01855 3e7152f682b58fdf7a525c37b69f64fd 432 Gene3D G3DSA:3.50.50.60 19 172 1.3E-24 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS01855 3e7152f682b58fdf7a525c37b69f64fd 432 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 161 176 1.8E-12 T 10-11-2016 A4G23_RS01855 3e7152f682b58fdf7a525c37b69f64fd 432 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 21 43 1.8E-12 T 10-11-2016 A4G23_RS01855 3e7152f682b58fdf7a525c37b69f64fd 432 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 280 295 1.8E-12 T 10-11-2016 A4G23_RS01855 3e7152f682b58fdf7a525c37b69f64fd 432 SUPERFAMILY SSF51905 277 367 3.12E-40 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS01855 3e7152f682b58fdf7a525c37b69f64fd 432 SUPERFAMILY SSF51905 20 188 3.12E-40 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS01855 3e7152f682b58fdf7a525c37b69f64fd 432 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 20 315 1.1E-80 T 10-11-2016 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 A4G23_RS01855 3e7152f682b58fdf7a525c37b69f64fd 432 Pfam PF01494 FAD binding domain 108 301 2.4E-7 T 10-11-2016 IPR002938 FAD-binding domain GO:0071949 A4G23_RS01855 3e7152f682b58fdf7a525c37b69f64fd 432 Pfam PF00890 FAD binding domain 21 67 7.7E-7 T 10-11-2016 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4G23_RS01855 3e7152f682b58fdf7a525c37b69f64fd 432 Gene3D G3DSA:3.30.9.10 173 324 2.5E-26 T 10-11-2016 A4G23_RS08865 61c1ea8088da242cdcdc0e15cbe530f7 325 PRINTS PR00116 Arginase signature 125 140 1.6E-14 T 10-11-2016 IPR006035 Ureohydrolase GO:0046872 A4G23_RS08865 61c1ea8088da242cdcdc0e15cbe530f7 325 PRINTS PR00116 Arginase signature 238 267 1.6E-14 T 10-11-2016 IPR006035 Ureohydrolase GO:0046872 A4G23_RS08865 61c1ea8088da242cdcdc0e15cbe530f7 325 Gene3D G3DSA:3.40.800.10 13 315 2.6E-117 T 10-11-2016 IPR023696 Ureohydrolase domain A4G23_RS08865 61c1ea8088da242cdcdc0e15cbe530f7 325 ProSitePatterns PS01053 Arginase family signature. 241 262 - T 10-11-2016 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 A4G23_RS08865 61c1ea8088da242cdcdc0e15cbe530f7 325 SUPERFAMILY SSF52768 18 313 9.36E-99 T 10-11-2016 A4G23_RS08865 61c1ea8088da242cdcdc0e15cbe530f7 325 TIGRFAM TIGR01230 agmatinase: agmatinase 37 310 1.7E-69 T 10-11-2016 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 A4G23_RS08865 61c1ea8088da242cdcdc0e15cbe530f7 325 Pfam PF00491 Arginase family 38 309 1.4E-90 T 10-11-2016 IPR006035 Ureohydrolase GO:0046872 A4G23_RS08865 61c1ea8088da242cdcdc0e15cbe530f7 325 PIRSF PIRSF036979 16 317 3.8E-109 T 10-11-2016 IPR006035 Ureohydrolase GO:0046872 A4G23_RS24985 981e34266a3a431db0e0d35be7b64534 29 TIGRFAM TIGR02115 potass_kdpF: K+-transporting ATPase, F subunit 7 29 1.1E-10 T 10-11-2016 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 A4G23_RS24985 981e34266a3a431db0e0d35be7b64534 29 Pfam PF09604 F subunit of K+-transporting ATPase (Potass_KdpF) 6 29 1.3E-9 T 10-11-2016 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 A4G23_RS02705 87bf72900cdb6bd4b75bbf1d311224bb 290 SUPERFAMILY SSF53335 24 241 4.45E-52 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS02705 87bf72900cdb6bd4b75bbf1d311224bb 290 SMART SM00828 Methyltransferase in polyketide synthase (PKS) enzymes. 66 287 0.0099 T 10-11-2016 IPR020803 Polyketide synthase, methyltransferase domain A4G23_RS02705 87bf72900cdb6bd4b75bbf1d311224bb 290 Pfam PF08241 Methyltransferase domain 83 181 3.3E-24 T 10-11-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 A4G23_RS02705 87bf72900cdb6bd4b75bbf1d311224bb 290 Gene3D G3DSA:3.40.50.150 44 252 2.6E-52 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS25590 973c70b3c62f099cfb7fab45315e2d59 530 Gene3D G3DSA:2.60.40.1610 80 208 6.3E-42 T 10-11-2016 IPR010679 Domain of unknown function DUF1254 A4G23_RS25590 973c70b3c62f099cfb7fab45315e2d59 530 Gene3D G3DSA:1.10.3360.10 243 329 1.2E-26 T 10-11-2016 IPR023289 VPA0735-like domain A4G23_RS25590 973c70b3c62f099cfb7fab45315e2d59 530 Pfam PF06863 Protein of unknown function (DUF1254) 91 204 4.1E-22 T 10-11-2016 IPR010679 Domain of unknown function DUF1254 A4G23_RS25590 973c70b3c62f099cfb7fab45315e2d59 530 SUPERFAMILY SSF160935 242 527 1.18E-105 T 10-11-2016 A4G23_RS25590 973c70b3c62f099cfb7fab45315e2d59 530 SUPERFAMILY SSF160935 20 212 1.18E-105 T 10-11-2016 A4G23_RS25590 973c70b3c62f099cfb7fab45315e2d59 530 Pfam PF06742 Protein of unknown function (DUF1214) 404 512 3.5E-25 T 10-11-2016 IPR010621 Domain of unknown function DUF1214 A4G23_RS25590 973c70b3c62f099cfb7fab45315e2d59 530 Gene3D G3DSA:2.60.120.600 373 528 2.9E-44 T 10-11-2016 IPR010621 Domain of unknown function DUF1214 A4G23_RS03935 def21bfc044a953e85dc150c483166cc 378 Gene3D G3DSA:3.30.70.260 252 332 1.2E-20 T 10-11-2016 A4G23_RS03935 def21bfc044a953e85dc150c483166cc 378 SUPERFAMILY SSF55021 254 333 1.26E-16 T 10-11-2016 A4G23_RS03935 def21bfc044a953e85dc150c483166cc 378 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS03935 def21bfc044a953e85dc150c483166cc 378 Pfam PF00005 ABC transporter 21 175 2.5E-34 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS03935 def21bfc044a953e85dc150c483166cc 378 Gene3D G3DSA:3.40.50.300 2 242 2.9E-81 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS03935 def21bfc044a953e85dc150c483166cc 378 SMART SM00382 30 232 2.1E-11 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS03935 def21bfc044a953e85dc150c483166cc 378 SMART SM00930 257 332 1.5E-19 T 10-11-2016 IPR018449 NIL domain A4G23_RS03935 def21bfc044a953e85dc150c483166cc 378 SUPERFAMILY SSF52540 1 242 8.23E-79 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS03935 def21bfc044a953e85dc150c483166cc 378 Pfam PF09383 NIL domain 259 331 3.7E-17 T 10-11-2016 IPR018449 NIL domain A4G23_RS07815 5823e358a8145d49c852c19baf021e70 295 Gene3D G3DSA:1.10.3470.10 41 259 8.9E-10 T 10-11-2016 IPR029022 ABC transporter, BtuC-like A4G23_RS07815 5823e358a8145d49c852c19baf021e70 295 SUPERFAMILY SSF81345 4 258 6.28E-35 T 10-11-2016 IPR029022 ABC transporter, BtuC-like A4G23_RS07815 5823e358a8145d49c852c19baf021e70 295 Pfam PF00950 ABC 3 transport family 6 259 8.9E-63 T 10-11-2016 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 A4G23_RS13800 7aa50b1ff14af1bacf8914eb3288e3c9 638 Gene3D G3DSA:2.60.40.1220 25 123 8.8E-26 T 10-11-2016 IPR014755 Copper resistance protein CopC/internalin, immunoglobulin-like A4G23_RS13800 7aa50b1ff14af1bacf8914eb3288e3c9 638 Pfam PF05425 Copper resistance protein D 334 408 1.8E-18 T 10-11-2016 IPR008457 Copper resistance protein D GO:0016021 A4G23_RS13800 7aa50b1ff14af1bacf8914eb3288e3c9 638 Pfam PF04234 CopC domain 26 123 2.1E-23 T 10-11-2016 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 A4G23_RS13800 7aa50b1ff14af1bacf8914eb3288e3c9 638 SUPERFAMILY SSF81296 25 123 2.24E-21 T 10-11-2016 IPR014756 Immunoglobulin E-set A4G23_RS10620 fd2d7cd8476b6f359c7de3765cc57a03 230 SMART SM00421 153 210 3.2E-18 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS10620 fd2d7cd8476b6f359c7de3765cc57a03 230 SUPERFAMILY SSF46894 141 217 5.1E-18 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS10620 fd2d7cd8476b6f359c7de3765cc57a03 230 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 3.4E-9 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS10620 fd2d7cd8476b6f359c7de3765cc57a03 230 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 3.4E-9 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS10620 fd2d7cd8476b6f359c7de3765cc57a03 230 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 3.4E-9 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS10620 fd2d7cd8476b6f359c7de3765cc57a03 230 SUPERFAMILY SSF52172 2 123 7.12E-13 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS10620 fd2d7cd8476b6f359c7de3765cc57a03 230 Pfam PF00072 Response regulator receiver domain 6 106 3.4E-7 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS10620 fd2d7cd8476b6f359c7de3765cc57a03 230 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 210 1.2E-14 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS10620 fd2d7cd8476b6f359c7de3765cc57a03 230 Gene3D G3DSA:1.10.10.10 122 217 4.2E-20 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS10620 fd2d7cd8476b6f359c7de3765cc57a03 230 Gene3D G3DSA:3.40.50.2300 2 121 7.9E-15 T 10-11-2016 A4G23_RS00410 c9ced29796e8f42e49e4bcb1d6514f27 407 Pfam PF07690 Major Facilitator Superfamily 21 342 8.6E-17 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS00410 c9ced29796e8f42e49e4bcb1d6514f27 407 SUPERFAMILY SSF103473 5 377 4.19E-38 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS00410 c9ced29796e8f42e49e4bcb1d6514f27 407 Gene3D G3DSA:1.20.1250.20 4 178 4.1E-13 T 10-11-2016 A4G23_RS00410 c9ced29796e8f42e49e4bcb1d6514f27 407 Gene3D G3DSA:1.20.1250.20 203 381 1.5E-14 T 10-11-2016 A4G23_RS15785 33e490fd0bb0412473b2f2a6449356bf 397 Pfam PF01139 tRNA-splicing ligase RtcB 29 397 2.8E-128 T 10-11-2016 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 A4G23_RS15785 33e490fd0bb0412473b2f2a6449356bf 397 SUPERFAMILY SSF103365 11 397 2.48E-129 T 10-11-2016 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 A4G23_RS23735 9231f179c6508c5552f9185420f0bb84 307 Gene3D G3DSA:3.40.50.620 1 135 9.5E-31 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS23735 9231f179c6508c5552f9185420f0bb84 307 Gene3D G3DSA:3.40.50.620 166 305 1.2E-23 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS23735 9231f179c6508c5552f9185420f0bb84 307 Pfam PF00582 Universal stress protein family 168 305 4.8E-14 T 10-11-2016 IPR006016 UspA GO:0006950 A4G23_RS23735 9231f179c6508c5552f9185420f0bb84 307 Pfam PF00582 Universal stress protein family 1 135 1.6E-20 T 10-11-2016 IPR006016 UspA GO:0006950 A4G23_RS23735 9231f179c6508c5552f9185420f0bb84 307 SUPERFAMILY SSF52402 3 139 3.93E-27 T 10-11-2016 A4G23_RS23735 9231f179c6508c5552f9185420f0bb84 307 PRINTS PR01438 Universal stress protein signature 113 135 6.6E-11 T 10-11-2016 IPR006015 Universal stress protein A A4G23_RS23735 9231f179c6508c5552f9185420f0bb84 307 PRINTS PR01438 Universal stress protein signature 2 20 6.6E-11 T 10-11-2016 IPR006015 Universal stress protein A A4G23_RS23735 9231f179c6508c5552f9185420f0bb84 307 PRINTS PR01438 Universal stress protein signature 95 107 6.6E-11 T 10-11-2016 IPR006015 Universal stress protein A A4G23_RS23735 9231f179c6508c5552f9185420f0bb84 307 SUPERFAMILY SSF52402 168 306 3.93E-21 T 10-11-2016 A4G23_RS19735 161053d3b0ee9b70c6de1d391952e68e 110 Pfam PF12823 Domain of unknown function (DUF3817) 6 93 9.9E-27 T 10-11-2016 IPR023845 Domain of unknown function DUF3817, transmembrane A4G23_RS19735 161053d3b0ee9b70c6de1d391952e68e 110 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 9 92 2.9E-27 T 10-11-2016 IPR023845 Domain of unknown function DUF3817, transmembrane A4G23_RS03350 a801da42925a234c48a6640209569f0d 282 Pfam PF08029 HisG, C-terminal domain 207 278 2.7E-26 T 10-11-2016 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 A4G23_RS03350 a801da42925a234c48a6640209569f0d 282 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 2 182 1.5E-49 T 10-11-2016 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 A4G23_RS03350 a801da42925a234c48a6640209569f0d 282 Gene3D G3DSA:3.30.70.120 210 281 2.5E-29 T 10-11-2016 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal A4G23_RS03350 a801da42925a234c48a6640209569f0d 282 TIGRFAM TIGR03455 HisG_C-term: ATP phosphoribosyltransferase, C-terminal domain 192 281 3.2E-29 T 10-11-2016 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 A4G23_RS03350 a801da42925a234c48a6640209569f0d 282 SUPERFAMILY SSF53850 1 208 8.69E-59 T 10-11-2016 A4G23_RS03350 a801da42925a234c48a6640209569f0d 282 Pfam PF01634 ATP phosphoribosyltransferase 49 203 1.7E-38 T 10-11-2016 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 A4G23_RS03350 a801da42925a234c48a6640209569f0d 282 Gene3D G3DSA:3.40.190.10 109 173 1.5E-23 T 10-11-2016 A4G23_RS03350 a801da42925a234c48a6640209569f0d 282 Gene3D G3DSA:3.40.190.10 1 108 2.8E-32 T 10-11-2016 A4G23_RS03350 a801da42925a234c48a6640209569f0d 282 Hamap MF_00079 ATP phosphoribosyltransferase [hisG]. 1 282 31.866 T 10-11-2016 IPR020621 ATP phosphoribosyltransferase HisG, long form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 A4G23_RS03350 a801da42925a234c48a6640209569f0d 282 SUPERFAMILY SSF54913 210 281 7.45E-22 T 10-11-2016 IPR011322 Nitrogen regulatory PII-like, alpha/beta A4G23_RS15370 990299f47983803d54e7a17c2674b438 409 Gene3D G3DSA:3.40.640.10 50 279 4.9E-37 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS15370 990299f47983803d54e7a17c2674b438 409 SUPERFAMILY SSF53383 74 331 1.26E-58 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS15370 990299f47983803d54e7a17c2674b438 409 Pfam PF01212 Beta-eliminating lyase 77 302 4.5E-26 T 10-11-2016 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 A4G23_RS09940 cb08a555fc4fa05abe5cf0c4c84ac6f4 391 PIRSF PIRSF001480 1 391 1.3E-92 T 10-11-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 A4G23_RS09940 cb08a555fc4fa05abe5cf0c4c84ac6f4 391 Gene3D G3DSA:2.60.120.10 242 277 2.3E-57 T 10-11-2016 IPR014710 RmlC-like jelly roll fold A4G23_RS09940 cb08a555fc4fa05abe5cf0c4c84ac6f4 391 Gene3D G3DSA:2.60.120.10 7 143 2.3E-57 T 10-11-2016 IPR014710 RmlC-like jelly roll fold A4G23_RS09940 cb08a555fc4fa05abe5cf0c4c84ac6f4 391 Gene3D G3DSA:2.60.120.10 292 389 4.6E-11 T 10-11-2016 IPR014710 RmlC-like jelly roll fold A4G23_RS09940 cb08a555fc4fa05abe5cf0c4c84ac6f4 391 SUPERFAMILY SSF51182 2 383 1.48E-94 T 10-11-2016 IPR011051 RmlC-like cupin domain A4G23_RS09940 cb08a555fc4fa05abe5cf0c4c84ac6f4 391 Pfam PF01238 Phosphomannose isomerase type I 3 354 1.4E-61 T 10-11-2016 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 A4G23_RS09940 cb08a555fc4fa05abe5cf0c4c84ac6f4 391 Gene3D G3DSA:1.10.441.10 278 291 1.4E-20 T 10-11-2016 A4G23_RS09940 cb08a555fc4fa05abe5cf0c4c84ac6f4 391 Gene3D G3DSA:1.10.441.10 144 235 1.4E-20 T 10-11-2016 A4G23_RS09940 cb08a555fc4fa05abe5cf0c4c84ac6f4 391 PRINTS PR00714 Phosphomannose isomerase type I signature 129 152 2.0E-61 T 10-11-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 A4G23_RS09940 cb08a555fc4fa05abe5cf0c4c84ac6f4 391 PRINTS PR00714 Phosphomannose isomerase type I signature 278 297 2.0E-61 T 10-11-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 A4G23_RS09940 cb08a555fc4fa05abe5cf0c4c84ac6f4 391 PRINTS PR00714 Phosphomannose isomerase type I signature 31 46 2.0E-61 T 10-11-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 A4G23_RS09940 cb08a555fc4fa05abe5cf0c4c84ac6f4 391 PRINTS PR00714 Phosphomannose isomerase type I signature 240 259 2.0E-61 T 10-11-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 A4G23_RS09940 cb08a555fc4fa05abe5cf0c4c84ac6f4 391 PRINTS PR00714 Phosphomannose isomerase type I signature 259 278 2.0E-61 T 10-11-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 A4G23_RS09940 cb08a555fc4fa05abe5cf0c4c84ac6f4 391 PRINTS PR00714 Phosphomannose isomerase type I signature 224 239 2.0E-61 T 10-11-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 A4G23_RS09940 cb08a555fc4fa05abe5cf0c4c84ac6f4 391 PRINTS PR00714 Phosphomannose isomerase type I signature 4 22 2.0E-61 T 10-11-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 A4G23_RS09940 cb08a555fc4fa05abe5cf0c4c84ac6f4 391 PRINTS PR00714 Phosphomannose isomerase type I signature 84 105 2.0E-61 T 10-11-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 A4G23_RS09940 cb08a555fc4fa05abe5cf0c4c84ac6f4 391 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 4 384 1.8E-68 T 10-11-2016 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 A4G23_RS04500 370735627e932f6439eaafab4d3e76b6 176 Gene3D G3DSA:3.40.50.300 3 165 9.9E-63 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS04500 370735627e932f6439eaafab4d3e76b6 176 Pfam PF01202 Shikimate kinase 14 164 1.0E-8 T 10-11-2016 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 A4G23_RS04500 370735627e932f6439eaafab4d3e76b6 176 SUPERFAMILY SSF52540 1 166 2.62E-23 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS04500 370735627e932f6439eaafab4d3e76b6 176 TIGRFAM TIGR01313 therm_gnt_kin: carbohydrate kinase, thermoresistant glucokinase family 7 161 7.8E-55 T 10-11-2016 IPR006001 Carbohydrate kinase, thermoresistant glucokinase GO:0005975|GO:0016301 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530 A4G23_RS10995 1072af58c665b3126d15f4a0342b5f4a 826 Pfam PF00122 E1-E2 ATPase 262 482 3.9E-63 T 10-11-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 A4G23_RS10995 1072af58c665b3126d15f4a0342b5f4a 826 Gene3D G3DSA:3.40.1110.10 506 617 1.0E-20 T 10-11-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A4G23_RS10995 1072af58c665b3126d15f4a0342b5f4a 826 Pfam PF00702 haloacid dehalogenase-like hydrolase 487 704 4.9E-47 T 10-11-2016 A4G23_RS10995 1072af58c665b3126d15f4a0342b5f4a 826 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 213 800 1.2E-174 T 10-11-2016 A4G23_RS10995 1072af58c665b3126d15f4a0342b5f4a 826 Gene3D G3DSA:3.40.50.1000 462 505 9.0E-58 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS10995 1072af58c665b3126d15f4a0342b5f4a 826 Gene3D G3DSA:3.40.50.1000 618 758 9.0E-58 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS10995 1072af58c665b3126d15f4a0342b5f4a 826 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 340 354 1.7E-29 T 10-11-2016 A4G23_RS10995 1072af58c665b3126d15f4a0342b5f4a 826 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 713 725 1.7E-29 T 10-11-2016 A4G23_RS10995 1072af58c665b3126d15f4a0342b5f4a 826 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 690 709 1.7E-29 T 10-11-2016 A4G23_RS10995 1072af58c665b3126d15f4a0342b5f4a 826 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 637 647 1.7E-29 T 10-11-2016 A4G23_RS10995 1072af58c665b3126d15f4a0342b5f4a 826 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 491 505 1.7E-29 T 10-11-2016 A4G23_RS10995 1072af58c665b3126d15f4a0342b5f4a 826 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 615 626 1.7E-29 T 10-11-2016 A4G23_RS10995 1072af58c665b3126d15f4a0342b5f4a 826 SUPERFAMILY SSF56784 489 509 4.74E-59 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS10995 1072af58c665b3126d15f4a0342b5f4a 826 SUPERFAMILY SSF56784 548 797 4.74E-59 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS10995 1072af58c665b3126d15f4a0342b5f4a 826 Gene3D G3DSA:2.70.150.10 254 391 6.8E-30 T 10-11-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 A4G23_RS10995 1072af58c665b3126d15f4a0342b5f4a 826 SUPERFAMILY SSF81665 239 294 4.84E-14 T 10-11-2016 A4G23_RS10995 1072af58c665b3126d15f4a0342b5f4a 826 SUPERFAMILY SSF81665 391 485 4.84E-14 T 10-11-2016 A4G23_RS10995 1072af58c665b3126d15f4a0342b5f4a 826 SUPERFAMILY SSF81665 739 757 4.84E-14 T 10-11-2016 A4G23_RS10995 1072af58c665b3126d15f4a0342b5f4a 826 Pfam PF00403 Heavy-metal-associated domain 1 62 2.8E-8 T 10-11-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A4G23_RS10995 1072af58c665b3126d15f4a0342b5f4a 826 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 493 499 - T 10-11-2016 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 A4G23_RS10995 1072af58c665b3126d15f4a0342b5f4a 826 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 229 799 1.7E-183 T 10-11-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A4G23_RS10995 1072af58c665b3126d15f4a0342b5f4a 826 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 263 767 8.2E-86 T 10-11-2016 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A4G23_RS10995 1072af58c665b3126d15f4a0342b5f4a 826 SUPERFAMILY SSF81653 293 390 1.96E-27 T 10-11-2016 A4G23_RS10995 1072af58c665b3126d15f4a0342b5f4a 826 Gene3D G3DSA:3.30.70.100 2 64 4.5E-11 T 10-11-2016 A4G23_RS10995 1072af58c665b3126d15f4a0342b5f4a 826 SUPERFAMILY SSF55008 2 64 1.7E-11 T 10-11-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A4G23_RS10995 1072af58c665b3126d15f4a0342b5f4a 826 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 721 746 1.5E-5 T 10-11-2016 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A4G23_RS10995 1072af58c665b3126d15f4a0342b5f4a 826 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 690 706 1.5E-5 T 10-11-2016 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A4G23_RS18985 719ab680921742b7587ee0fac8cccf89 104 Gene3D G3DSA:2.30.30.110 2 102 1.6E-17 T 10-11-2016 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor A4G23_RS18985 719ab680921742b7587ee0fac8cccf89 104 SUPERFAMILY SSF50118 2 102 8.01E-17 T 10-11-2016 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor A4G23_RS18985 719ab680921742b7587ee0fac8cccf89 104 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 2 101 3.3E-14 T 10-11-2016 IPR003477 mRNA interferase PemK-like protein GO:0003677 A4G23_RS02110 ea3d5afffd3ebd90985b2558cffbb375 300 Pfam PF05653 Magnesium transporter NIPA 3 286 2.2E-7 T 10-11-2016 IPR008521 Magnesium transporter NIPA GO:0015095|GO:0015693|GO:0016021 Reactome: R-HSA-5223345 A4G23_RS02110 ea3d5afffd3ebd90985b2558cffbb375 300 SUPERFAMILY SSF103481 42 118 8.5E-6 T 10-11-2016 A4G23_RS13235 e7f16a6a642375dbccdd44a681039991 342 SUPERFAMILY SSF52922 205 335 1.23E-37 T 10-11-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 A4G23_RS13235 e7f16a6a642375dbccdd44a681039991 342 Gene3D G3DSA:3.40.50.920 212 333 1.2E-40 T 10-11-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 A4G23_RS13235 e7f16a6a642375dbccdd44a681039991 342 Pfam PF02779 Transketolase, pyrimidine binding domain 17 190 1.6E-46 T 10-11-2016 IPR005475 Transketolase-like, pyrimidine-binding domain A4G23_RS13235 e7f16a6a642375dbccdd44a681039991 342 Gene3D G3DSA:3.40.50.970 15 210 3.3E-76 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS13235 e7f16a6a642375dbccdd44a681039991 342 Pfam PF02780 Transketolase, C-terminal domain 208 329 1.1E-37 T 10-11-2016 IPR033248 Transketolase, C-terminal domain A4G23_RS13235 e7f16a6a642375dbccdd44a681039991 342 SMART SM00861 17 192 7.5E-68 T 10-11-2016 IPR005475 Transketolase-like, pyrimidine-binding domain A4G23_RS13235 e7f16a6a642375dbccdd44a681039991 342 SUPERFAMILY SSF52518 16 201 8.41E-68 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS20385 5a1154cb9363b18f7ae19984572a70c2 555 Pfam PF02734 DAK2 domain 35 212 1.3E-24 T 10-11-2016 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 A4G23_RS20385 5a1154cb9363b18f7ae19984572a70c2 555 SMART SM01121 247 555 1.5E-95 T 10-11-2016 IPR033470 Uncharacterised protein, DhaK domain A4G23_RS20385 5a1154cb9363b18f7ae19984572a70c2 555 Pfam PF13684 Dihydroxyacetone kinase family 249 555 3.2E-79 T 10-11-2016 IPR033470 Uncharacterised protein, DhaK domain A4G23_RS20385 5a1154cb9363b18f7ae19984572a70c2 555 SMART SM01120 35 213 9.4E-42 T 10-11-2016 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 A4G23_RS20385 5a1154cb9363b18f7ae19984572a70c2 555 TIGRFAM TIGR03599 YloV: DAK2 domain fusion protein YloV 11 555 5.0E-128 T 10-11-2016 IPR019986 DAK2 domain-containing protein YloV A4G23_RS20385 5a1154cb9363b18f7ae19984572a70c2 555 SUPERFAMILY SSF101473 6 215 1.57E-28 T 10-11-2016 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 A4G23_RS12895 aea1b275fc823912415a60bd66bcecc7 749 SUPERFAMILY SSF56042 583 748 2.39E-39 T 10-11-2016 IPR010918 AIR synthase-related protein, C-terminal domain A4G23_RS12895 aea1b275fc823912415a60bd66bcecc7 749 Gene3D G3DSA:3.30.1330.10 56 203 8.0E-52 T 10-11-2016 IPR016188 PurM-like, N-terminal domain A4G23_RS12895 aea1b275fc823912415a60bd66bcecc7 749 Gene3D G3DSA:3.30.1330.10 427 575 3.0E-54 T 10-11-2016 IPR016188 PurM-like, N-terminal domain A4G23_RS12895 aea1b275fc823912415a60bd66bcecc7 749 SUPERFAMILY SSF56042 209 439 5.08E-52 T 10-11-2016 IPR010918 AIR synthase-related protein, C-terminal domain A4G23_RS12895 aea1b275fc823912415a60bd66bcecc7 749 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 24 746 1.3E-261 T 10-11-2016 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A4G23_RS12895 aea1b275fc823912415a60bd66bcecc7 749 Pfam PF02769 AIR synthase related protein, C-terminal domain 211 366 3.0E-33 T 10-11-2016 IPR010918 AIR synthase-related protein, C-terminal domain A4G23_RS12895 aea1b275fc823912415a60bd66bcecc7 749 Pfam PF02769 AIR synthase related protein, C-terminal domain 585 722 1.4E-20 T 10-11-2016 IPR010918 AIR synthase-related protein, C-terminal domain A4G23_RS12895 aea1b275fc823912415a60bd66bcecc7 749 Gene3D G3DSA:3.90.650.10 259 364 2.8E-4 T 10-11-2016 IPR010918 AIR synthase-related protein, C-terminal domain A4G23_RS12895 aea1b275fc823912415a60bd66bcecc7 749 SUPERFAMILY SSF55326 19 204 1.18E-49 T 10-11-2016 A4G23_RS12895 aea1b275fc823912415a60bd66bcecc7 749 Pfam PF00586 AIR synthase related protein, N-terminal domain 96 198 4.3E-22 T 10-11-2016 IPR016188 PurM-like, N-terminal domain A4G23_RS12895 aea1b275fc823912415a60bd66bcecc7 749 Pfam PF00586 AIR synthase related protein, N-terminal domain 454 572 5.1E-23 T 10-11-2016 IPR016188 PurM-like, N-terminal domain A4G23_RS12895 aea1b275fc823912415a60bd66bcecc7 749 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 749 309.685 T 10-11-2016 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A4G23_RS12895 aea1b275fc823912415a60bd66bcecc7 749 PIRSF PIRSF001587 6 749 8.1E-289 T 10-11-2016 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A4G23_RS12895 aea1b275fc823912415a60bd66bcecc7 749 SUPERFAMILY SSF55326 409 578 1.44E-55 T 10-11-2016 A4G23_RS23890 9142a8f58e1ce126fce4a8930a837596 251 Pfam PF07730 Histidine kinase 172 238 8.9E-18 T 10-11-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4G23_RS25935 b8d2b3a1417a73bd41477f3e9477e391 186 SUPERFAMILY SSF46785 3 181 4.22E-41 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS25935 b8d2b3a1417a73bd41477f3e9477e391 186 Pfam PF10400 Virulence activator alpha C-term 92 179 2.8E-24 T 10-11-2016 IPR018309 Transcription regulator PadR, C-terminal A4G23_RS25935 b8d2b3a1417a73bd41477f3e9477e391 186 Gene3D G3DSA:1.10.10.10 1 87 5.5E-29 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS25935 b8d2b3a1417a73bd41477f3e9477e391 186 Pfam PF03551 Transcriptional regulator PadR-like family 7 80 2.6E-14 T 10-11-2016 IPR005149 Transcription regulator PadR, N-terminal A4G23_RS24495 931edc24f862c079009b668c9a82bcdc 397 Pfam PF00155 Aminotransferase class I and II 46 387 3.4E-71 T 10-11-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4G23_RS24495 931edc24f862c079009b668c9a82bcdc 397 TIGRFAM TIGR01822 2am3keto_CoA: glycine C-acetyltransferase 6 390 5.0E-193 T 10-11-2016 IPR011282 2-amino-3-ketobutyrate coenzyme A ligase GO:0006567|GO:0008890 KEGG: 00260+2.3.1.29|Reactome: R-HSA-8849175 A4G23_RS24495 931edc24f862c079009b668c9a82bcdc 397 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 242 251 - T 10-11-2016 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 A4G23_RS24495 931edc24f862c079009b668c9a82bcdc 397 SUPERFAMILY SSF53383 6 392 4.12E-119 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS24495 931edc24f862c079009b668c9a82bcdc 397 Gene3D G3DSA:3.90.1150.10 280 391 8.7E-31 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS24495 931edc24f862c079009b668c9a82bcdc 397 Gene3D G3DSA:3.40.640.10 63 279 3.1E-89 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS24495 931edc24f862c079009b668c9a82bcdc 397 Hamap MF_00985 2-amino-3-ketobutyrate coenzyme A ligase [kbl]. 2 396 54.165 T 10-11-2016 IPR011282 2-amino-3-ketobutyrate coenzyme A ligase GO:0006567|GO:0008890 KEGG: 00260+2.3.1.29|Reactome: R-HSA-8849175 A4G23_RS10695 8d5f6b46082803e5dd8e304f3be94bde 570 SUPERFAMILY SSF49265 262 452 3.73E-9 T 10-11-2016 IPR003961 Fibronectin type III GO:0005515 A4G23_RS10695 8d5f6b46082803e5dd8e304f3be94bde 570 Pfam PF07691 PA14 domain 34 141 1.7E-6 T 10-11-2016 IPR011658 PA14 domain A4G23_RS10695 8d5f6b46082803e5dd8e304f3be94bde 570 Gene3D G3DSA:3.90.182.10 19 170 7.7E-17 T 10-11-2016 IPR011658 PA14 domain A4G23_RS10695 8d5f6b46082803e5dd8e304f3be94bde 570 Gene3D G3DSA:2.60.40.10 171 254 2.9E-9 T 10-11-2016 IPR013783 Immunoglobulin-like fold A4G23_RS10695 8d5f6b46082803e5dd8e304f3be94bde 570 SMART SM00758 27 164 0.0065 T 10-11-2016 IPR011658 PA14 domain A4G23_RS10695 8d5f6b46082803e5dd8e304f3be94bde 570 SUPERFAMILY SSF49265 163 259 6.06E-5 T 10-11-2016 IPR003961 Fibronectin type III GO:0005515 A4G23_RS10695 8d5f6b46082803e5dd8e304f3be94bde 570 SUPERFAMILY SSF56988 34 199 3.14E-9 T 10-11-2016 A4G23_RS10695 8d5f6b46082803e5dd8e304f3be94bde 570 SMART SM00060 457 547 190.0 T 10-11-2016 IPR003961 Fibronectin type III GO:0005515 A4G23_RS10695 8d5f6b46082803e5dd8e304f3be94bde 570 SMART SM00060 164 246 27.0 T 10-11-2016 IPR003961 Fibronectin type III GO:0005515 A4G23_RS10695 8d5f6b46082803e5dd8e304f3be94bde 570 SMART SM00060 263 342 4.5 T 10-11-2016 IPR003961 Fibronectin type III GO:0005515 A4G23_RS10695 8d5f6b46082803e5dd8e304f3be94bde 570 SMART SM00060 358 441 2.0 T 10-11-2016 IPR003961 Fibronectin type III GO:0005515 A4G23_RS10695 8d5f6b46082803e5dd8e304f3be94bde 570 Gene3D G3DSA:2.60.40.10 360 445 1.5E-8 T 10-11-2016 IPR013783 Immunoglobulin-like fold A4G23_RS10695 8d5f6b46082803e5dd8e304f3be94bde 570 Gene3D G3DSA:2.60.40.10 265 350 4.0E-12 T 10-11-2016 IPR013783 Immunoglobulin-like fold A4G23_RS10695 8d5f6b46082803e5dd8e304f3be94bde 570 Gene3D G3DSA:2.60.40.10 463 547 7.6E-5 T 10-11-2016 IPR013783 Immunoglobulin-like fold A4G23_RS23920 b5839d9a6e8139fc918788a4c46bbdd8 409 Pfam PF07730 Histidine kinase 202 267 3.3E-14 T 10-11-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4G23_RS23920 b5839d9a6e8139fc918788a4c46bbdd8 409 SUPERFAMILY SSF55874 288 406 2.07E-9 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS25335 f777c3df784faee32aa99618b84f6d99 424 Gene3D G3DSA:3.40.640.10 22 270 1.1E-65 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS25335 f777c3df784faee32aa99618b84f6d99 424 SUPERFAMILY SSF53383 16 416 4.52E-84 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS25335 f777c3df784faee32aa99618b84f6d99 424 PIRSF PIRSF000390 14 406 6.7E-86 T 10-11-2016 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A4G23_RS25335 f777c3df784faee32aa99618b84f6d99 424 Gene3D G3DSA:3.90.1150.10 273 418 8.0E-30 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS25335 f777c3df784faee32aa99618b84f6d99 424 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 31 412 1.9E-103 T 10-11-2016 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A4G23_RS21490 c47753e56df8ce908ed0c2b21a4228ec 277 PRINTS PR00377 Inositol monophosphatase superfamily signature 191 212 1.4E-44 T 10-11-2016 IPR000760 Inositol monophosphatase GO:0046854 A4G23_RS21490 c47753e56df8ce908ed0c2b21a4228ec 277 PRINTS PR00377 Inositol monophosphatase superfamily signature 76 92 1.4E-44 T 10-11-2016 IPR000760 Inositol monophosphatase GO:0046854 A4G23_RS21490 c47753e56df8ce908ed0c2b21a4228ec 277 PRINTS PR00377 Inositol monophosphatase superfamily signature 222 246 1.4E-44 T 10-11-2016 IPR000760 Inositol monophosphatase GO:0046854 A4G23_RS21490 c47753e56df8ce908ed0c2b21a4228ec 277 PRINTS PR00377 Inositol monophosphatase superfamily signature 145 168 1.4E-44 T 10-11-2016 IPR000760 Inositol monophosphatase GO:0046854 A4G23_RS21490 c47753e56df8ce908ed0c2b21a4228ec 277 PRINTS PR00377 Inositol monophosphatase superfamily signature 54 74 1.4E-44 T 10-11-2016 IPR000760 Inositol monophosphatase GO:0046854 A4G23_RS21490 c47753e56df8ce908ed0c2b21a4228ec 277 PRINTS PR00377 Inositol monophosphatase superfamily signature 96 112 1.4E-44 T 10-11-2016 IPR000760 Inositol monophosphatase GO:0046854 A4G23_RS21490 c47753e56df8ce908ed0c2b21a4228ec 277 Pfam PF00459 Inositol monophosphatase family 17 240 4.6E-57 T 10-11-2016 IPR000760 Inositol monophosphatase GO:0046854 A4G23_RS21490 c47753e56df8ce908ed0c2b21a4228ec 277 SUPERFAMILY SSF56655 17 270 2.09E-72 T 10-11-2016 A4G23_RS21490 c47753e56df8ce908ed0c2b21a4228ec 277 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 225 239 - T 10-11-2016 IPR020550 Inositol monophosphatase, conserved site GO:0046854 A4G23_RS21490 c47753e56df8ce908ed0c2b21a4228ec 277 Gene3D G3DSA:3.30.540.10 16 166 7.9E-48 T 10-11-2016 A4G23_RS21490 c47753e56df8ce908ed0c2b21a4228ec 277 Gene3D G3DSA:3.40.190.80 167 271 2.9E-27 T 10-11-2016 A4G23_RS21490 c47753e56df8ce908ed0c2b21a4228ec 277 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 96 109 - T 10-11-2016 IPR020583 Inositol monophosphatase, metal-binding site A4G23_RS23105 06ca27230a5165c88fb57ad2cc2c6563 193 Pfam PF08002 Protein of unknown function (DUF1697) 5 140 8.0E-40 T 10-11-2016 IPR012545 Protein of unknown function DUF1697 A4G23_RS23105 06ca27230a5165c88fb57ad2cc2c6563 193 PIRSF PIRSF008502 4 185 1.3E-45 T 10-11-2016 IPR012545 Protein of unknown function DUF1697 A4G23_RS23105 06ca27230a5165c88fb57ad2cc2c6563 193 Gene3D G3DSA:3.30.70.1280 4 91 4.2E-27 T 10-11-2016 A4G23_RS23105 06ca27230a5165c88fb57ad2cc2c6563 193 SUPERFAMILY SSF160379 6 183 2.48E-49 T 10-11-2016 A4G23_RS01060 85d67281f86f7f3cd5821343253ce3ad 551 Pfam PF02543 Carbamoyltransferase N-terminus 2 74 5.7E-11 T 10-11-2016 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 A4G23_RS01060 85d67281f86f7f3cd5821343253ce3ad 551 Pfam PF02543 Carbamoyltransferase N-terminus 114 326 1.0E-41 T 10-11-2016 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 A4G23_RS01060 85d67281f86f7f3cd5821343253ce3ad 551 SUPERFAMILY SSF53067 122 329 6.09E-15 T 10-11-2016 A4G23_RS01060 85d67281f86f7f3cd5821343253ce3ad 551 SUPERFAMILY SSF53067 1 88 6.09E-15 T 10-11-2016 A4G23_RS01060 85d67281f86f7f3cd5821343253ce3ad 551 SUPERFAMILY SSF55821 366 541 1.13E-7 T 10-11-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain A4G23_RS01060 85d67281f86f7f3cd5821343253ce3ad 551 Pfam PF16861 Carbamoyltransferase C-terminus 375 542 8.6E-66 T 10-11-2016 IPR031730 Carbamoyltransferase, C-terminal A4G23_RS26125 a18978467bf3109b7f0a6f91be318bbc 397 Gene3D G3DSA:1.20.140.10 210 387 3.1E-27 T 10-11-2016 A4G23_RS26125 a18978467bf3109b7f0a6f91be318bbc 397 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 114 198 2.5E-20 T 10-11-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 A4G23_RS26125 a18978467bf3109b7f0a6f91be318bbc 397 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 110 1.4E-10 T 10-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 A4G23_RS26125 a18978467bf3109b7f0a6f91be318bbc 397 SUPERFAMILY SSF47203 221 380 1.26E-16 T 10-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4G23_RS26125 a18978467bf3109b7f0a6f91be318bbc 397 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 221 378 1.2E-18 T 10-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4G23_RS26125 a18978467bf3109b7f0a6f91be318bbc 397 SUPERFAMILY SSF56645 11 233 1.18E-60 T 10-11-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 A4G23_RS26125 a18978467bf3109b7f0a6f91be318bbc 397 Gene3D G3DSA:2.40.110.10 113 209 4.6E-31 T 10-11-2016 A4G23_RS26125 a18978467bf3109b7f0a6f91be318bbc 397 Gene3D G3DSA:1.10.540.10 11 111 3.5E-15 T 10-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 A4G23_RS08545 ccc4377f535671d19f8055b2758fab60 554 Pfam PF00005 ABC transporter 338 471 1.5E-21 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS08545 ccc4377f535671d19f8055b2758fab60 554 Pfam PF00005 ABC transporter 21 188 2.7E-26 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS08545 ccc4377f535671d19f8055b2758fab60 554 Gene3D G3DSA:3.40.50.300 319 529 1.5E-44 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS08545 ccc4377f535671d19f8055b2758fab60 554 ProSitePatterns PS00211 ABC transporters family signature. 443 457 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS08545 ccc4377f535671d19f8055b2758fab60 554 Gene3D G3DSA:3.40.50.300 8 105 8.9E-54 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS08545 ccc4377f535671d19f8055b2758fab60 554 Gene3D G3DSA:3.40.50.300 138 284 8.9E-54 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS08545 ccc4377f535671d19f8055b2758fab60 554 SUPERFAMILY SSF52540 306 514 1.29E-46 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS08545 ccc4377f535671d19f8055b2758fab60 554 Pfam PF12848 ABC transporter 227 303 7.8E-12 T 10-11-2016 IPR032781 ABC-transporter extension domain A4G23_RS08545 ccc4377f535671d19f8055b2758fab60 554 SUPERFAMILY SSF52540 11 241 3.2E-50 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS08545 ccc4377f535671d19f8055b2758fab60 554 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 3 551 2.1E-277 T 10-11-2016 IPR022374 ABC transporter, ATP-binding protein, ChvD A4G23_RS08545 ccc4377f535671d19f8055b2758fab60 554 SMART SM00382 30 233 3.6E-12 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS08545 ccc4377f535671d19f8055b2758fab60 554 SMART SM00382 346 516 1.9E-8 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS08545 ccc4377f535671d19f8055b2758fab60 554 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS26270 ed5cc0e61bd5503f48ec933dcd7d11a9 166 SMART SM00421 103 160 6.9E-18 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS26270 ed5cc0e61bd5503f48ec933dcd7d11a9 166 Gene3D G3DSA:1.10.10.10 100 165 1.2E-20 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS26270 ed5cc0e61bd5503f48ec933dcd7d11a9 166 SUPERFAMILY SSF46894 94 166 1.05E-17 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS26270 ed5cc0e61bd5503f48ec933dcd7d11a9 166 Pfam PF00196 Bacterial regulatory proteins, luxR family 105 160 3.1E-14 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS26270 ed5cc0e61bd5503f48ec933dcd7d11a9 166 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 106 120 5.8E-7 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS26270 ed5cc0e61bd5503f48ec933dcd7d11a9 166 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 136 148 5.8E-7 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS26270 ed5cc0e61bd5503f48ec933dcd7d11a9 166 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 120 136 5.8E-7 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS09800 b930a4a5591252bf222e13a495fb5799 1646 SUPERFAMILY SSF51735 975 1077 7.88E-30 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS09800 b930a4a5591252bf222e13a495fb5799 1646 SUPERFAMILY SSF51735 1115 1319 7.88E-30 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS09800 b930a4a5591252bf222e13a495fb5799 1646 PIRSF PIRSF036761 2 1646 0.0 T 10-11-2016 IPR007780 NAD-glutamate dehydrogenase, bacteria GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 A4G23_RS09800 b930a4a5591252bf222e13a495fb5799 1646 SUPERFAMILY SSF53223 784 970 4.12E-21 T 10-11-2016 A4G23_RS09800 b930a4a5591252bf222e13a495fb5799 1646 Pfam PF05088 Bacterial NAD-glutamate dehydrogenase 78 1639 0.0 T 10-11-2016 IPR028971 NAD-glutamate dehydrogenase GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 A4G23_RS09800 b930a4a5591252bf222e13a495fb5799 1646 Gene3D G3DSA:3.40.50.720 972 1083 7.8E-35 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS09800 b930a4a5591252bf222e13a495fb5799 1646 Gene3D G3DSA:3.40.50.720 1140 1228 7.8E-35 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS26630 fbd4119eb0a8847fff3cbb3d4fd15740 197 SUPERFAMILY SSF46689 1 77 3.59E-14 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS26630 fbd4119eb0a8847fff3cbb3d4fd15740 197 Gene3D G3DSA:1.10.357.10 1 195 7.3E-38 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS26630 fbd4119eb0a8847fff3cbb3d4fd15740 197 SUPERFAMILY SSF48498 98 196 1.65E-14 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS26630 fbd4119eb0a8847fff3cbb3d4fd15740 197 Pfam PF13977 Bacterial transcriptional repressor 92 196 1.7E-17 T 10-11-2016 A4G23_RS26630 fbd4119eb0a8847fff3cbb3d4fd15740 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 57 3.8E-8 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS07025 b8c23d9e1ad89b501910832a30e42ce4 502 ProSitePatterns PS00216 Sugar transport proteins signature 1. 155 171 - T 10-11-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A4G23_RS07025 b8c23d9e1ad89b501910832a30e42ce4 502 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 101 483 3.2E-102 T 10-11-2016 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 A4G23_RS07025 b8c23d9e1ad89b501910832a30e42ce4 502 Pfam PF07690 Major Facilitator Superfamily 113 451 3.2E-42 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS07025 b8c23d9e1ad89b501910832a30e42ce4 502 Gene3D G3DSA:1.20.1250.20 300 492 2.1E-7 T 10-11-2016 A4G23_RS07025 b8c23d9e1ad89b501910832a30e42ce4 502 Gene3D G3DSA:1.20.1250.20 104 285 1.1E-29 T 10-11-2016 A4G23_RS07025 b8c23d9e1ad89b501910832a30e42ce4 502 SUPERFAMILY SSF103473 87 490 1.57E-65 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS11655 ceeff6d92c32d27aca08ce1ecbd7c507 311 Gene3D G3DSA:3.40.190.10 89 175 1.8E-20 T 10-11-2016 A4G23_RS11655 ceeff6d92c32d27aca08ce1ecbd7c507 311 Gene3D G3DSA:3.40.190.10 176 262 2.7E-19 T 10-11-2016 A4G23_RS11655 ceeff6d92c32d27aca08ce1ecbd7c507 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.7E-8 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS11655 ceeff6d92c32d27aca08ce1ecbd7c507 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.7E-8 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS11655 ceeff6d92c32d27aca08ce1ecbd7c507 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.7E-8 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS11655 ceeff6d92c32d27aca08ce1ecbd7c507 311 SUPERFAMILY SSF46785 2 109 7.26E-21 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS11655 ceeff6d92c32d27aca08ce1ecbd7c507 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 7.5E-19 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS11655 ceeff6d92c32d27aca08ce1ecbd7c507 311 SUPERFAMILY SSF53850 87 295 2.95E-44 T 10-11-2016 A4G23_RS11655 ceeff6d92c32d27aca08ce1ecbd7c507 311 Pfam PF03466 LysR substrate binding domain 86 287 3.6E-49 T 10-11-2016 IPR005119 LysR, substrate-binding A4G23_RS11655 ceeff6d92c32d27aca08ce1ecbd7c507 311 Gene3D G3DSA:1.10.10.10 2 79 4.7E-25 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS08860 257a519cb7d4587ef97f4c26c49df0b1 562 SUPERFAMILY SSF52518 26 203 1.33E-39 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS08860 257a519cb7d4587ef97f4c26c49df0b1 562 Gene3D G3DSA:3.40.50.970 384 547 5.2E-47 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS08860 257a519cb7d4587ef97f4c26c49df0b1 562 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 220 348 1.0E-30 T 10-11-2016 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 A4G23_RS08860 257a519cb7d4587ef97f4c26c49df0b1 562 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 407 547 3.7E-34 T 10-11-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A4G23_RS08860 257a519cb7d4587ef97f4c26c49df0b1 562 SUPERFAMILY SSF52518 385 549 8.04E-46 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS08860 257a519cb7d4587ef97f4c26c49df0b1 562 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 27 197 1.9E-45 T 10-11-2016 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 A4G23_RS08860 257a519cb7d4587ef97f4c26c49df0b1 562 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 440 459 - T 10-11-2016 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 A4G23_RS08860 257a519cb7d4587ef97f4c26c49df0b1 562 Gene3D G3DSA:3.40.50.1220 211 362 2.1E-43 T 10-11-2016 IPR029035 DHS-like NAD/FAD-binding domain A4G23_RS08860 257a519cb7d4587ef97f4c26c49df0b1 562 SUPERFAMILY SSF52467 181 376 1.52E-36 T 10-11-2016 IPR029035 DHS-like NAD/FAD-binding domain A4G23_RS08860 257a519cb7d4587ef97f4c26c49df0b1 562 Gene3D G3DSA:3.40.50.970 26 201 1.4E-49 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS23350 af475f39a2de1d76afc9582cbcb3c282 208 Pfam PF00881 Nitroreductase family 5 184 7.1E-26 T 10-11-2016 IPR029479 Nitroreductase Reactome: R-HSA-209968 A4G23_RS23350 af475f39a2de1d76afc9582cbcb3c282 208 Gene3D G3DSA:3.40.109.10 3 195 2.3E-46 T 10-11-2016 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4G23_RS23350 af475f39a2de1d76afc9582cbcb3c282 208 SUPERFAMILY SSF55469 3 91 3.8E-43 T 10-11-2016 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4G23_RS23350 af475f39a2de1d76afc9582cbcb3c282 208 SUPERFAMILY SSF55469 120 207 3.8E-43 T 10-11-2016 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4G23_RS07800 5e415519020b3290781d90166f16b0f6 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 403 422 2.2E-50 T 10-11-2016 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A4G23_RS07800 5e415519020b3290781d90166f16b0f6 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 25 39 2.2E-50 T 10-11-2016 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A4G23_RS07800 5e415519020b3290781d90166f16b0f6 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 317 329 2.2E-50 T 10-11-2016 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A4G23_RS07800 5e415519020b3290781d90166f16b0f6 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 190 207 2.2E-50 T 10-11-2016 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A4G23_RS07800 5e415519020b3290781d90166f16b0f6 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 137 149 2.2E-50 T 10-11-2016 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A4G23_RS07800 5e415519020b3290781d90166f16b0f6 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 207 217 2.2E-50 T 10-11-2016 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A4G23_RS07800 5e415519020b3290781d90166f16b0f6 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 158 175 2.2E-50 T 10-11-2016 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A4G23_RS07800 5e415519020b3290781d90166f16b0f6 460 Gene3D G3DSA:3.30.930.10 7 361 4.5E-141 T 10-11-2016 A4G23_RS07800 5e415519020b3290781d90166f16b0f6 460 SUPERFAMILY SSF55681 5 369 4.3E-119 T 10-11-2016 A4G23_RS07800 5e415519020b3290781d90166f16b0f6 460 Gene3D G3DSA:3.40.50.800 362 456 1.9E-40 T 10-11-2016 IPR004154 Anticodon-binding A4G23_RS07800 5e415519020b3290781d90166f16b0f6 460 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 6 231 1.8E-81 T 10-11-2016 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A4G23_RS07800 5e415519020b3290781d90166f16b0f6 460 Pfam PF03129 Anticodon binding domain 366 454 4.2E-23 T 10-11-2016 IPR004154 Anticodon-binding A4G23_RS07800 5e415519020b3290781d90166f16b0f6 460 Hamap MF_00253_B Glycine--tRNA ligase [glyQS]. 3 458 49.502 T 10-11-2016 IPR022961 Glycine-tRNA ligase, bacterial GO:0004820 KEGG: 00970+6.1.1.14 A4G23_RS07800 5e415519020b3290781d90166f16b0f6 460 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 157 333 8.8E-10 T 10-11-2016 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4G23_RS07800 5e415519020b3290781d90166f16b0f6 460 SUPERFAMILY SSF52954 354 457 4.08E-34 T 10-11-2016 IPR004154 Anticodon-binding A4G23_RS16290 c5aa9391727b5d814fbe373ba0faa169 54 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 6 54 19.823 T 10-11-2016 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS16290 c5aa9391727b5d814fbe373ba0faa169 54 Pfam PF00471 Ribosomal protein L33 9 54 2.6E-23 T 10-11-2016 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS16290 c5aa9391727b5d814fbe373ba0faa169 54 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 2 54 2.6E-22 T 10-11-2016 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS16290 c5aa9391727b5d814fbe373ba0faa169 54 ProSitePatterns PS00582 Ribosomal protein L33 signature. 22 41 - T 10-11-2016 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS16290 c5aa9391727b5d814fbe373ba0faa169 54 SUPERFAMILY SSF57829 4 54 3.66E-20 T 10-11-2016 IPR011332 Zinc-binding ribosomal protein GO:0006412 A4G23_RS04685 e0ee1af3b2c97cccf54a20f45108ad60 235 SUPERFAMILY SSF48498 92 234 3.29E-20 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS04685 e0ee1af3b2c97cccf54a20f45108ad60 235 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 88 234 7.3E-15 T 10-11-2016 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 A4G23_RS04685 e0ee1af3b2c97cccf54a20f45108ad60 235 Pfam PF00440 Bacterial regulatory proteins, tetR family 31 75 1.7E-8 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS04685 e0ee1af3b2c97cccf54a20f45108ad60 235 SUPERFAMILY SSF46689 20 84 4.44E-15 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS04685 e0ee1af3b2c97cccf54a20f45108ad60 235 Gene3D G3DSA:1.10.357.10 17 234 6.0E-54 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS24345 e38dc2e7b7e7ccea0033cb62ff50b18b 295 SUPERFAMILY SSF103481 187 284 1.02E-11 T 10-11-2016 A4G23_RS24345 e38dc2e7b7e7ccea0033cb62ff50b18b 295 SUPERFAMILY SSF103481 34 134 2.88E-5 T 10-11-2016 A4G23_RS24345 e38dc2e7b7e7ccea0033cb62ff50b18b 295 Pfam PF00892 EamA-like transporter family 148 280 6.7E-12 T 10-11-2016 IPR000620 EamA domain GO:0016020|GO:0016021 A4G23_RS27125 c79828b8f5d275b048bd3d06916e15b7 113 SUPERFAMILY SSF48452 3 105 4.07E-13 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS27125 c79828b8f5d275b048bd3d06916e15b7 113 Pfam PF14559 Tetratricopeptide repeat 22 84 7.4E-12 T 10-11-2016 A4G23_RS27125 c79828b8f5d275b048bd3d06916e15b7 113 Gene3D G3DSA:1.25.40.10 16 106 6.7E-13 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS18145 8d36e250fa307ee9a02f45af8be3546b 211 PRINTS PR01021 OMPA domain signature 106 128 1.9E-6 T 10-11-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 A4G23_RS18145 8d36e250fa307ee9a02f45af8be3546b 211 PRINTS PR01021 OMPA domain signature 136 151 1.9E-6 T 10-11-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 A4G23_RS18145 8d36e250fa307ee9a02f45af8be3546b 211 PRINTS PR01021 OMPA domain signature 151 167 1.9E-6 T 10-11-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 A4G23_RS18145 8d36e250fa307ee9a02f45af8be3546b 211 Pfam PF00691 OmpA family 106 201 1.3E-14 T 10-11-2016 IPR006665 OmpA-like domain A4G23_RS18145 8d36e250fa307ee9a02f45af8be3546b 211 SUPERFAMILY SSF103088 94 207 1.23E-27 T 10-11-2016 IPR006665 OmpA-like domain A4G23_RS18145 8d36e250fa307ee9a02f45af8be3546b 211 Gene3D G3DSA:3.30.1330.60 89 207 4.0E-28 T 10-11-2016 IPR006665 OmpA-like domain A4G23_RS07860 20fb5fe39d1f473b96b7c481b79af9a6 316 TIGRFAM TIGR00436 era: GTP-binding protein Era 18 299 3.2E-65 T 10-11-2016 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 A4G23_RS07860 20fb5fe39d1f473b96b7c481b79af9a6 316 Gene3D G3DSA:3.30.300.20 203 313 3.0E-36 T 10-11-2016 IPR015946 K homology domain-like, alpha/beta A4G23_RS07860 20fb5fe39d1f473b96b7c481b79af9a6 316 Hamap MF_00367 GTPase Era [era]. 15 316 34.419 T 10-11-2016 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 A4G23_RS07860 20fb5fe39d1f473b96b7c481b79af9a6 316 Pfam PF01926 50S ribosome-binding GTPase 21 134 2.9E-20 T 10-11-2016 IPR006073 GTP binding domain GO:0005525 A4G23_RS07860 20fb5fe39d1f473b96b7c481b79af9a6 316 SUPERFAMILY SSF54814 197 316 8.5E-35 T 10-11-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 A4G23_RS07860 20fb5fe39d1f473b96b7c481b79af9a6 316 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 22 147 1.3E-15 T 10-11-2016 IPR005225 Small GTP-binding protein domain GO:0005525 A4G23_RS07860 20fb5fe39d1f473b96b7c481b79af9a6 316 Gene3D G3DSA:3.40.50.300 11 188 7.1E-36 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS07860 20fb5fe39d1f473b96b7c481b79af9a6 316 Pfam PF07650 KH domain 223 305 1.6E-16 T 10-11-2016 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS07860 20fb5fe39d1f473b96b7c481b79af9a6 316 SUPERFAMILY SSF52540 21 228 8.67E-40 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS09665 e841c94ea9453558781c0d7222ae6b24 93 Gene3D G3DSA:4.10.520.10 1 91 7.8E-29 T 10-11-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 A4G23_RS09665 e841c94ea9453558781c0d7222ae6b24 93 Pfam PF00216 Bacterial DNA-binding protein 1 90 1.5E-27 T 10-11-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 A4G23_RS09665 e841c94ea9453558781c0d7222ae6b24 93 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 47 66 - T 10-11-2016 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 A4G23_RS09665 e841c94ea9453558781c0d7222ae6b24 93 SUPERFAMILY SSF47729 1 91 5.45E-26 T 10-11-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 A4G23_RS09665 e841c94ea9453558781c0d7222ae6b24 93 PRINTS PR01727 Prokaryotic integration host factor signature 59 72 4.2E-8 T 10-11-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 A4G23_RS09665 e841c94ea9453558781c0d7222ae6b24 93 PRINTS PR01727 Prokaryotic integration host factor signature 41 56 4.2E-8 T 10-11-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 A4G23_RS09665 e841c94ea9453558781c0d7222ae6b24 93 PRINTS PR01727 Prokaryotic integration host factor signature 75 89 4.2E-8 T 10-11-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 A4G23_RS09665 e841c94ea9453558781c0d7222ae6b24 93 SMART SM00411 1 91 7.0E-38 T 10-11-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 A4G23_RS04415 bc0f8f52445722e23426940ef8d71f5a 330 SUPERFAMILY SSF144083 265 327 4.84E-19 T 10-11-2016 A4G23_RS04415 bc0f8f52445722e23426940ef8d71f5a 330 Pfam PF01544 CorA-like Mg2+ transporter protein 36 326 5.7E-66 T 10-11-2016 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 A4G23_RS04415 bc0f8f52445722e23426940ef8d71f5a 330 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 35 330 1.7E-62 T 10-11-2016 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 A4G23_RS04415 bc0f8f52445722e23426940ef8d71f5a 330 Gene3D G3DSA:1.20.58.340 138 251 1.5E-36 T 10-11-2016 A4G23_RS04415 bc0f8f52445722e23426940ef8d71f5a 330 Gene3D G3DSA:3.30.460.20 4 137 4.5E-42 T 10-11-2016 A4G23_RS04415 bc0f8f52445722e23426940ef8d71f5a 330 SUPERFAMILY SSF143865 5 262 1.57E-65 T 10-11-2016 A4G23_RS04415 bc0f8f52445722e23426940ef8d71f5a 330 Gene3D G3DSA:1.20.58.340 254 330 2.2E-25 T 10-11-2016 A4G23_RS18385 4c4a4bab6668c1b419e4c495641532c1 133 Pfam PF00293 NUDIX domain 14 110 3.1E-11 T 10-11-2016 IPR000086 NUDIX hydrolase domain GO:0016787 A4G23_RS18385 4c4a4bab6668c1b419e4c495641532c1 133 Gene3D G3DSA:3.90.79.10 8 128 2.5E-19 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS18385 4c4a4bab6668c1b419e4c495641532c1 133 ProSitePatterns PS00893 Nudix box signature. 34 55 - T 10-11-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A4G23_RS18385 4c4a4bab6668c1b419e4c495641532c1 133 SUPERFAMILY SSF55811 7 128 2.3E-21 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS08790 99cac33ddddace83e9993ef9e45aa3d4 183 Pfam PF13527 Acetyltransferase (GNAT) domain 3 129 1.8E-12 T 10-11-2016 A4G23_RS08790 99cac33ddddace83e9993ef9e45aa3d4 183 SUPERFAMILY SSF55729 1 132 1.65E-27 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS08790 99cac33ddddace83e9993ef9e45aa3d4 183 Gene3D G3DSA:3.40.630.30 1 129 3.7E-19 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS08740 0ed97ff9d618cb2bd6eeb65eebff04af 193 Pfam PF13302 Acetyltransferase (GNAT) domain 15 152 1.9E-18 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS08740 0ed97ff9d618cb2bd6eeb65eebff04af 193 SUPERFAMILY SSF55729 6 177 2.16E-43 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS08740 0ed97ff9d618cb2bd6eeb65eebff04af 193 Gene3D G3DSA:3.40.630.30 7 182 1.3E-48 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS17545 545273eb8af07fbe6e53828a351a8b46 531 SUPERFAMILY SSF53756 124 369 1.44E-10 T 10-11-2016 A4G23_RS10005 83174b0bd4f63e6ca50426a5c4127f4c 360 Gene3D G3DSA:3.90.550.10 2 238 1.9E-63 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS10005 83174b0bd4f63e6ca50426a5c4127f4c 360 Gene3D G3DSA:2.160.10.10 258 348 5.7E-16 T 10-11-2016 A4G23_RS10005 83174b0bd4f63e6ca50426a5c4127f4c 360 Pfam PF00483 Nucleotidyl transferase 4 236 4.8E-43 T 10-11-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A4G23_RS10005 83174b0bd4f63e6ca50426a5c4127f4c 360 SUPERFAMILY SSF53448 4 242 5.14E-66 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS10005 83174b0bd4f63e6ca50426a5c4127f4c 360 SUPERFAMILY SSF53448 279 328 5.14E-66 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS10005 83174b0bd4f63e6ca50426a5c4127f4c 360 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 307 333 2.9E-4 T 10-11-2016 IPR001451 Hexapeptide repeat A4G23_RS20125 dc5c81f08850f5f6975704e9b8b3e36d 174 Gene3D G3DSA:3.30.70.1150 84 163 3.2E-31 T 10-11-2016 A4G23_RS20125 dc5c81f08850f5f6975704e9b8b3e36d 174 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 3 158 3.2E-61 T 10-11-2016 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 A4G23_RS20125 dc5c81f08850f5f6975704e9b8b3e36d 174 SUPERFAMILY SSF55021 81 161 2.52E-26 T 10-11-2016 A4G23_RS20125 dc5c81f08850f5f6975704e9b8b3e36d 174 Gene3D G3DSA:3.30.70.260 1 78 4.5E-34 T 10-11-2016 A4G23_RS20125 dc5c81f08850f5f6975704e9b8b3e36d 174 SUPERFAMILY SSF55021 3 75 2.92E-22 T 10-11-2016 A4G23_RS20125 dc5c81f08850f5f6975704e9b8b3e36d 174 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 3 77 6.0E-35 T 10-11-2016 A4G23_RS20125 dc5c81f08850f5f6975704e9b8b3e36d 174 Pfam PF13710 ACT domain 13 74 4.4E-16 T 10-11-2016 A4G23_RS20125 dc5c81f08850f5f6975704e9b8b3e36d 174 Pfam PF10369 Small subunit of acetolactate synthase 85 158 6.3E-29 T 10-11-2016 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 A4G23_RS21995 94e14810787e71a09d422375a8f0f757 976 Pfam PF03639 Glycosyl hydrolase family 81 122 534 6.3E-67 T 10-11-2016 IPR005200 Endo-1,3(4)-beta-glucanase GO:0052861 A4G23_RS21995 94e14810787e71a09d422375a8f0f757 976 SUPERFAMILY SSF49265 633 816 4.15E-27 T 10-11-2016 IPR003961 Fibronectin type III GO:0005515 A4G23_RS21995 94e14810787e71a09d422375a8f0f757 976 Gene3D G3DSA:2.60.40.10 726 810 5.6E-21 T 10-11-2016 IPR013783 Immunoglobulin-like fold A4G23_RS21995 94e14810787e71a09d422375a8f0f757 976 Gene3D G3DSA:2.60.40.10 633 719 1.2E-21 T 10-11-2016 IPR013783 Immunoglobulin-like fold A4G23_RS21995 94e14810787e71a09d422375a8f0f757 976 SMART SM00060 635 709 2.9E-11 T 10-11-2016 IPR003961 Fibronectin type III GO:0005515 A4G23_RS21995 94e14810787e71a09d422375a8f0f757 976 SMART SM00060 727 800 8.7E-11 T 10-11-2016 IPR003961 Fibronectin type III GO:0005515 A4G23_RS13575 a589b18a1a94ab079360d706df427d65 475 PIRSF PIRSF010361 21 470 2.2E-143 T 10-11-2016 IPR016570 Uncharacterised conserved protein UCP010361, membrane A4G23_RS13575 a589b18a1a94ab079360d706df427d65 475 Pfam PF09594 Protein of unknown function (DUF2029) 126 357 1.1E-13 T 10-11-2016 IPR018584 Glycosyltransferase family 87 GO:0016758 A4G23_RS22495 6e6f95a6e11e3e4d55dbce9c7b572b18 159 SUPERFAMILY SSF46785 7 68 7.45E-17 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS22495 6e6f95a6e11e3e4d55dbce9c7b572b18 159 Gene3D G3DSA:3.30.70.920 62 141 6.3E-19 T 10-11-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A4G23_RS22495 6e6f95a6e11e3e4d55dbce9c7b572b18 159 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 35 54 2.2E-12 T 10-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 A4G23_RS22495 6e6f95a6e11e3e4d55dbce9c7b572b18 159 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 8 24 2.2E-12 T 10-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 A4G23_RS22495 6e6f95a6e11e3e4d55dbce9c7b572b18 159 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 24 35 2.2E-12 T 10-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 A4G23_RS22495 6e6f95a6e11e3e4d55dbce9c7b572b18 159 SMART SM00344 8 115 5.8E-39 T 10-11-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A4G23_RS22495 6e6f95a6e11e3e4d55dbce9c7b572b18 159 Pfam PF13404 AsnC-type helix-turn-helix domain 8 49 3.9E-17 T 10-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 A4G23_RS22495 6e6f95a6e11e3e4d55dbce9c7b572b18 159 Gene3D G3DSA:1.10.10.10 7 59 6.0E-21 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS22495 6e6f95a6e11e3e4d55dbce9c7b572b18 159 SUPERFAMILY SSF54909 69 146 6.3E-14 T 10-11-2016 IPR011008 Dimeric alpha-beta barrel A4G23_RS22495 6e6f95a6e11e3e4d55dbce9c7b572b18 159 Pfam PF01037 Lrp/AsnC ligand binding domain 74 143 3.8E-15 T 10-11-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A4G23_RS19950 5bc682812e2bf8c3769ec6043eced0fe 124 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 121 8.8E-45 T 10-11-2016 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 A4G23_RS19950 5bc682812e2bf8c3769ec6043eced0fe 124 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 4 124 29.212 T 10-11-2016 IPR002930 Glycine cleavage system H-protein A4G23_RS19950 5bc682812e2bf8c3769ec6043eced0fe 124 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 48 77 - T 10-11-2016 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 A4G23_RS19950 5bc682812e2bf8c3769ec6043eced0fe 124 Pfam PF01597 Glycine cleavage H-protein 7 122 1.8E-41 T 10-11-2016 IPR002930 Glycine cleavage system H-protein A4G23_RS19950 5bc682812e2bf8c3769ec6043eced0fe 124 Gene3D G3DSA:2.40.50.100 6 122 7.1E-45 T 10-11-2016 A4G23_RS19950 5bc682812e2bf8c3769ec6043eced0fe 124 SUPERFAMILY SSF51230 4 122 4.19E-38 T 10-11-2016 IPR011053 Single hybrid motif A4G23_RS02745 2ebb5014c180b073ffa31e427fcfb3aa 985 Pfam PF00196 Bacterial regulatory proteins, luxR family 929 983 6.2E-16 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS02745 2ebb5014c180b073ffa31e427fcfb3aa 985 SUPERFAMILY SSF46894 918 983 6.12E-17 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS02745 2ebb5014c180b073ffa31e427fcfb3aa 985 Gene3D G3DSA:1.25.40.10 569 820 4.8E-12 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS02745 2ebb5014c180b073ffa31e427fcfb3aa 985 SUPERFAMILY SSF48452 587 657 8.47E-7 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS02745 2ebb5014c180b073ffa31e427fcfb3aa 985 SUPERFAMILY SSF48452 703 735 8.47E-7 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS02745 2ebb5014c180b073ffa31e427fcfb3aa 985 Pfam PF13191 AAA ATPase domain 11 187 5.6E-9 T 10-11-2016 A4G23_RS02745 2ebb5014c180b073ffa31e427fcfb3aa 985 SMART SM00421 927 984 3.4E-18 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS02745 2ebb5014c180b073ffa31e427fcfb3aa 985 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 944 960 1.5E-7 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS02745 2ebb5014c180b073ffa31e427fcfb3aa 985 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 930 944 1.5E-7 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS02745 2ebb5014c180b073ffa31e427fcfb3aa 985 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 960 972 1.5E-7 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS02745 2ebb5014c180b073ffa31e427fcfb3aa 985 Gene3D G3DSA:1.10.10.10 916 982 2.6E-20 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS13540 72554e8a4fa15cbb5a366e7091c8ad72 776 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 240 766 1.6E-144 T 10-11-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ A4G23_RS13540 72554e8a4fa15cbb5a366e7091c8ad72 776 Pfam PF03023 MviN-like protein 268 740 1.2E-125 T 10-11-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ A4G23_RS13540 72554e8a4fa15cbb5a366e7091c8ad72 776 PRINTS PR01806 Virulence factor MviN signature 611 630 7.7E-19 T 10-11-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ A4G23_RS13540 72554e8a4fa15cbb5a366e7091c8ad72 776 PRINTS PR01806 Virulence factor MviN signature 289 305 7.7E-19 T 10-11-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ A4G23_RS13540 72554e8a4fa15cbb5a366e7091c8ad72 776 PRINTS PR01806 Virulence factor MviN signature 270 289 7.7E-19 T 10-11-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ A4G23_RS13540 72554e8a4fa15cbb5a366e7091c8ad72 776 PRINTS PR01806 Virulence factor MviN signature 369 393 7.7E-19 T 10-11-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ A4G23_RS13540 72554e8a4fa15cbb5a366e7091c8ad72 776 PRINTS PR01806 Virulence factor MviN signature 393 414 7.7E-19 T 10-11-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ A4G23_RS13540 72554e8a4fa15cbb5a366e7091c8ad72 776 PRINTS PR01806 Virulence factor MviN signature 667 684 7.7E-19 T 10-11-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ A4G23_RS11860 80845bdd8fbeccf3ac64c31715960707 127 PRINTS PR00050 Cold shock protein signature 38 56 1.5E-13 T 10-11-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4G23_RS11860 80845bdd8fbeccf3ac64c31715960707 127 PRINTS PR00050 Cold shock protein signature 24 33 1.5E-13 T 10-11-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4G23_RS11860 80845bdd8fbeccf3ac64c31715960707 127 PRINTS PR00050 Cold shock protein signature 4 19 1.5E-13 T 10-11-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4G23_RS11860 80845bdd8fbeccf3ac64c31715960707 127 SUPERFAMILY SSF50249 2 65 1.27E-18 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS11860 80845bdd8fbeccf3ac64c31715960707 127 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 10-11-2016 IPR019844 Cold-shock conserved site A4G23_RS11860 80845bdd8fbeccf3ac64c31715960707 127 SMART SM00357 3 65 1.0E-21 T 10-11-2016 IPR011129 Cold shock protein GO:0003676 A4G23_RS11860 80845bdd8fbeccf3ac64c31715960707 127 Pfam PF00313 'Cold-shock' DNA-binding domain 3 64 2.2E-20 T 10-11-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4G23_RS11860 80845bdd8fbeccf3ac64c31715960707 127 Gene3D G3DSA:2.40.50.140 3 64 4.8E-24 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS23100 c2f7eebaa107436b5c1ac27bc1b386af 287 Pfam PF01636 Phosphotransferase enzyme family 33 235 1.8E-18 T 10-11-2016 IPR002575 Aminoglycoside phosphotransferase A4G23_RS23100 c2f7eebaa107436b5c1ac27bc1b386af 287 SUPERFAMILY SSF56112 2 262 2.38E-34 T 10-11-2016 IPR011009 Protein kinase-like domain A4G23_RS23100 c2f7eebaa107436b5c1ac27bc1b386af 287 Gene3D G3DSA:3.90.1200.10 96 269 2.9E-14 T 10-11-2016 A4G23_RS08540 e907a02f7b00869b332317826d3c6ece 144 Pfam PF03061 Thioesterase superfamily 18 101 3.9E-17 T 10-11-2016 IPR006683 Thioesterase domain Reactome: R-HSA-75105 A4G23_RS08540 e907a02f7b00869b332317826d3c6ece 144 Gene3D G3DSA:3.10.129.10 3 134 1.1E-47 T 10-11-2016 IPR029069 HotDog domain A4G23_RS08540 e907a02f7b00869b332317826d3c6ece 144 SUPERFAMILY SSF54637 4 133 4.92E-35 T 10-11-2016 IPR029069 HotDog domain A4G23_RS21425 67d03a4363d5d5aa0ed3dd6138144715 256 Pfam PF01551 Peptidase family M23 148 244 2.5E-29 T 10-11-2016 IPR016047 Peptidase M23 A4G23_RS21425 67d03a4363d5d5aa0ed3dd6138144715 256 SUPERFAMILY SSF51261 98 249 5.75E-42 T 10-11-2016 IPR011055 Duplicated hybrid motif A4G23_RS21425 67d03a4363d5d5aa0ed3dd6138144715 256 Gene3D G3DSA:2.70.70.10 97 250 1.3E-43 T 10-11-2016 A4G23_RS23405 ad79c07952c4072440dc5bbb6291ba63 333 Gene3D G3DSA:3.40.50.1980 61 171 4.1E-13 T 10-11-2016 A4G23_RS23405 ad79c07952c4072440dc5bbb6291ba63 333 Gene3D G3DSA:3.40.50.1980 172 332 4.9E-18 T 10-11-2016 A4G23_RS23405 ad79c07952c4072440dc5bbb6291ba63 333 Pfam PF01497 Periplasmic binding protein 81 309 2.5E-16 T 10-11-2016 IPR002491 ABC transporter periplasmic binding domain GO:0005488 A4G23_RS23405 ad79c07952c4072440dc5bbb6291ba63 333 SUPERFAMILY SSF53807 62 325 4.32E-36 T 10-11-2016 A4G23_RS00360 97d8e9e9c520c787e562d497c130f6d7 337 Gene3D G3DSA:2.60.120.10 31 268 7.8E-61 T 10-11-2016 IPR014710 RmlC-like jelly roll fold A4G23_RS00360 97d8e9e9c520c787e562d497c130f6d7 337 SUPERFAMILY SSF51182 41 307 4.29E-70 T 10-11-2016 IPR011051 RmlC-like cupin domain A4G23_RS00360 97d8e9e9c520c787e562d497c130f6d7 337 Pfam PF05726 Pirin C-terminal cupin domain 193 292 3.8E-15 T 10-11-2016 IPR008778 Pirin, C-terminal domain A4G23_RS00360 97d8e9e9c520c787e562d497c130f6d7 337 PIRSF PIRSF006232 20 304 8.4E-79 T 10-11-2016 IPR012093 Pirin A4G23_RS00360 97d8e9e9c520c787e562d497c130f6d7 337 Pfam PF02678 Pirin 42 142 1.7E-30 T 10-11-2016 IPR003829 Pirin, N-terminal domain A4G23_RS10555 568e45098cbc40037f7528deb194b7b5 195 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 4 179 26.816 T 10-11-2016 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 A4G23_RS10555 568e45098cbc40037f7528deb194b7b5 195 Pfam PF01386 Ribosomal L25p family 6 90 2.9E-25 T 10-11-2016 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 A4G23_RS10555 568e45098cbc40037f7528deb194b7b5 195 Gene3D G3DSA:2.170.120.20 95 185 2.9E-22 T 10-11-2016 IPR020057 Ribosomal protein L25, beta domain A4G23_RS10555 568e45098cbc40037f7528deb194b7b5 195 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 99 178 4.7E-19 T 10-11-2016 IPR020057 Ribosomal protein L25, beta domain A4G23_RS10555 568e45098cbc40037f7528deb194b7b5 195 Gene3D G3DSA:2.40.240.10 4 92 1.6E-29 T 10-11-2016 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A4G23_RS10555 568e45098cbc40037f7528deb194b7b5 195 SUPERFAMILY SSF50715 4 185 5.41E-50 T 10-11-2016 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A4G23_RS10555 568e45098cbc40037f7528deb194b7b5 195 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 7 176 3.8E-44 T 10-11-2016 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 A4G23_RS10555 568e45098cbc40037f7528deb194b7b5 195 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 4 93 4.0E-39 T 10-11-2016 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 A4G23_RS17275 b3318fbc1bc7191ff6cd3cb29cffe0b1 641 SUPERFAMILY SSF161098 118 300 2.49E-36 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS17275 b3318fbc1bc7191ff6cd3cb29cffe0b1 641 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 470 627 1.5E-18 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS17275 b3318fbc1bc7191ff6cd3cb29cffe0b1 641 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 140 293 1.6E-19 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS17275 b3318fbc1bc7191ff6cd3cb29cffe0b1 641 SUPERFAMILY SSF161098 448 631 3.14E-33 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS17275 b3318fbc1bc7191ff6cd3cb29cffe0b1 641 Gene3D G3DSA:1.10.3720.10 117 295 3.4E-34 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS17275 b3318fbc1bc7191ff6cd3cb29cffe0b1 641 Gene3D G3DSA:1.10.3720.10 415 632 1.0E-30 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS05075 3ebb42f19a9eb0c8a3a80609a8eaf835 256 Pfam PF01464 Transglycosylase SLT domain 181 253 1.4E-8 T 10-11-2016 IPR008258 Transglycosylase SLT domain 1 A4G23_RS05075 3ebb42f19a9eb0c8a3a80609a8eaf835 256 Gene3D G3DSA:1.10.530.10 165 253 6.7E-10 T 10-11-2016 A4G23_RS05075 3ebb42f19a9eb0c8a3a80609a8eaf835 256 SUPERFAMILY SSF53955 142 250 2.53E-15 T 10-11-2016 IPR023346 Lysozyme-like domain A4G23_RS16205 3bb0e854600bfe66212bf58985a2a6e1 187 Pfam PF00037 4Fe-4S binding domain 95 115 2.4E-9 T 10-11-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4G23_RS16205 3bb0e854600bfe66212bf58985a2a6e1 187 Gene3D G3DSA:3.30.70.20 47 133 2.2E-16 T 10-11-2016 A4G23_RS16205 3bb0e854600bfe66212bf58985a2a6e1 187 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 3 170 23.955 T 10-11-2016 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16205 3bb0e854600bfe66212bf58985a2a6e1 187 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 51 62 - T 10-11-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4G23_RS16205 3bb0e854600bfe66212bf58985a2a6e1 187 SUPERFAMILY SSF54862 36 143 2.51E-19 T 10-11-2016 A4G23_RS16205 3bb0e854600bfe66212bf58985a2a6e1 187 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 100 111 - T 10-11-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4G23_RS00070 7798ef7c232479d68d47975e686fc46d 739 SUPERFAMILY SSF47413 25 71 1.96E-7 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS00070 7798ef7c232479d68d47975e686fc46d 739 Pfam PF01381 Helix-turn-helix 25 62 3.2E-8 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS00070 7798ef7c232479d68d47975e686fc46d 739 SMART SM00530 23 77 8.1E-5 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS00070 7798ef7c232479d68d47975e686fc46d 739 Gene3D G3DSA:1.10.260.40 25 72 1.2E-10 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS17470 9ecdcdb2ca79e753e412e2d6182fb074 373 Gene3D G3DSA:3.30.9.10 218 282 2.0E-8 T 10-11-2016 A4G23_RS17470 9ecdcdb2ca79e753e412e2d6182fb074 373 Gene3D G3DSA:3.30.9.10 77 143 2.0E-8 T 10-11-2016 A4G23_RS17470 9ecdcdb2ca79e753e412e2d6182fb074 373 Gene3D G3DSA:3.50.50.60 313 359 3.7E-45 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS17470 9ecdcdb2ca79e753e412e2d6182fb074 373 Gene3D G3DSA:3.50.50.60 144 217 3.7E-45 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS17470 9ecdcdb2ca79e753e412e2d6182fb074 373 Gene3D G3DSA:3.50.50.60 6 76 3.7E-45 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS17470 9ecdcdb2ca79e753e412e2d6182fb074 373 Pfam PF01266 FAD dependent oxidoreductase 8 351 4.4E-42 T 10-11-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A4G23_RS17470 9ecdcdb2ca79e753e412e2d6182fb074 373 SUPERFAMILY SSF51905 7 220 2.37E-47 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS17470 9ecdcdb2ca79e753e412e2d6182fb074 373 SUPERFAMILY SSF51905 313 361 2.37E-47 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS23500 3ceb4cda1d14678fa46c58d227f2b440 309 Hamap MF_00313 Glutaminase [glsA]. 9 309 43.971 T 10-11-2016 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 A4G23_RS23500 3ceb4cda1d14678fa46c58d227f2b440 309 TIGRFAM TIGR03814 Gln_ase: glutaminase A 13 309 1.5E-116 T 10-11-2016 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 A4G23_RS23500 3ceb4cda1d14678fa46c58d227f2b440 309 Pfam PF04960 Glutaminase 27 309 1.2E-105 T 10-11-2016 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 A4G23_RS23500 3ceb4cda1d14678fa46c58d227f2b440 309 Gene3D G3DSA:3.40.710.10 8 309 2.9E-112 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS23500 3ceb4cda1d14678fa46c58d227f2b440 309 SUPERFAMILY SSF56601 9 309 3.02E-100 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS03495 1d8ad5cc6edc7dda63702085c5b63ffc 310 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 2 301 1.1E-68 T 10-11-2016 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 A4G23_RS03495 1d8ad5cc6edc7dda63702085c5b63ffc 310 Gene3D G3DSA:3.40.50.170 2 206 1.5E-61 T 10-11-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A4G23_RS03495 1d8ad5cc6edc7dda63702085c5b63ffc 310 Pfam PF00551 Formyl transferase 3 177 3.8E-34 T 10-11-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A4G23_RS03495 1d8ad5cc6edc7dda63702085c5b63ffc 310 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 1 303 33.124 T 10-11-2016 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 A4G23_RS03495 1d8ad5cc6edc7dda63702085c5b63ffc 310 Pfam PF02911 Formyl transferase, C-terminal domain 204 300 1.8E-24 T 10-11-2016 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A4G23_RS03495 1d8ad5cc6edc7dda63702085c5b63ffc 310 SUPERFAMILY SSF50486 205 308 9.1E-29 T 10-11-2016 IPR011034 Formyl transferase, C-terminal-like GO:0003824 A4G23_RS03495 1d8ad5cc6edc7dda63702085c5b63ffc 310 Gene3D G3DSA:3.10.25.10 208 309 9.0E-32 T 10-11-2016 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A4G23_RS03495 1d8ad5cc6edc7dda63702085c5b63ffc 310 SUPERFAMILY SSF53328 2 204 1.7E-57 T 10-11-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A4G23_RS18365 3060e16a3a8c88fe02242a5c8ac249d3 524 Pfam PF00082 Subtilase family 155 384 9.3E-41 T 10-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4G23_RS18365 3060e16a3a8c88fe02242a5c8ac249d3 524 PRINTS PR00723 Subtilisin serine protease family (S8) signature 155 174 3.5E-20 T 10-11-2016 IPR015500 Peptidase S8, subtilisin-related A4G23_RS18365 3060e16a3a8c88fe02242a5c8ac249d3 524 PRINTS PR00723 Subtilisin serine protease family (S8) signature 346 362 3.5E-20 T 10-11-2016 IPR015500 Peptidase S8, subtilisin-related A4G23_RS18365 3060e16a3a8c88fe02242a5c8ac249d3 524 PRINTS PR00723 Subtilisin serine protease family (S8) signature 193 206 3.5E-20 T 10-11-2016 IPR015500 Peptidase S8, subtilisin-related A4G23_RS18365 3060e16a3a8c88fe02242a5c8ac249d3 524 Pfam PF01483 Proprotein convertase P-domain 445 524 8.4E-19 T 10-11-2016 IPR002884 Proprotein convertase, P GO:0004252|GO:0006508 A4G23_RS18365 3060e16a3a8c88fe02242a5c8ac249d3 524 Gene3D G3DSA:3.30.70.80 48 112 5.7E-20 T 10-11-2016 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 A4G23_RS18365 3060e16a3a8c88fe02242a5c8ac249d3 524 Pfam PF05922 Peptidase inhibitor I9 55 122 3.8E-12 T 10-11-2016 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 A4G23_RS18365 3060e16a3a8c88fe02242a5c8ac249d3 524 SUPERFAMILY SSF49785 420 524 2.55E-22 T 10-11-2016 IPR008979 Galactose-binding domain-like A4G23_RS18365 3060e16a3a8c88fe02242a5c8ac249d3 524 SUPERFAMILY SSF54897 54 123 5.27E-14 T 10-11-2016 IPR009020 Proteinase propeptide inhibitor A4G23_RS18365 3060e16a3a8c88fe02242a5c8ac249d3 524 Gene3D G3DSA:2.60.120.260 427 524 5.7E-14 T 10-11-2016 IPR008979 Galactose-binding domain-like A4G23_RS18365 3060e16a3a8c88fe02242a5c8ac249d3 524 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 347 357 - T 10-11-2016 IPR023828 Peptidase S8, subtilisin, Ser-active site A4G23_RS18365 3060e16a3a8c88fe02242a5c8ac249d3 524 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 197 207 - T 10-11-2016 IPR022398 Peptidase S8, subtilisin, His-active site A4G23_RS18365 3060e16a3a8c88fe02242a5c8ac249d3 524 SUPERFAMILY SSF52743 126 395 5.11E-77 T 10-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4G23_RS18365 3060e16a3a8c88fe02242a5c8ac249d3 524 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 160 171 - T 10-11-2016 IPR023827 Peptidase S8, subtilisin, Asp-active site A4G23_RS18365 3060e16a3a8c88fe02242a5c8ac249d3 524 Gene3D G3DSA:3.40.50.200 113 386 7.4E-88 T 10-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4G23_RS00160 dfcce6554b978f9cd60e330bd0a137c8 344 Gene3D G3DSA:1.10.10.10 262 327 8.1E-10 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS00160 dfcce6554b978f9cd60e330bd0a137c8 344 SMART SM00418 261 333 2.5E-5 T 10-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4G23_RS00160 dfcce6554b978f9cd60e330bd0a137c8 344 SUPERFAMILY SSF46785 261 333 4.04E-10 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS00160 dfcce6554b978f9cd60e330bd0a137c8 344 Pfam PF12840 Helix-turn-helix domain 262 318 4.0E-7 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS25765 7f22362afe5409fbe2005b5b74550b61 399 SMART SM00854 58 308 1.1E-80 T 10-11-2016 IPR019079 Capsule synthesis protein, CapA A4G23_RS25765 7f22362afe5409fbe2005b5b74550b61 399 Gene3D G3DSA:3.60.21.10 99 303 5.2E-16 T 10-11-2016 IPR029052 Metallo-dependent phosphatase-like A4G23_RS25765 7f22362afe5409fbe2005b5b74550b61 399 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 58 306 2.2E-69 T 10-11-2016 IPR019079 Capsule synthesis protein, CapA A4G23_RS25765 7f22362afe5409fbe2005b5b74550b61 399 SUPERFAMILY SSF56300 58 306 3.47E-35 T 10-11-2016 IPR029052 Metallo-dependent phosphatase-like A4G23_RS03040 c76fe16b4ef030b01e0d215094781a36 961 SUPERFAMILY SSF53383 20 446 2.23E-103 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS03040 c76fe16b4ef030b01e0d215094781a36 961 Pfam PF02347 Glycine cleavage system P-protein 454 736 1.2E-11 T 10-11-2016 IPR020580 Glycine cleavage system P-protein, N-terminal GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 A4G23_RS03040 c76fe16b4ef030b01e0d215094781a36 961 Pfam PF02347 Glycine cleavage system P-protein 19 447 4.5E-178 T 10-11-2016 IPR020580 Glycine cleavage system P-protein, N-terminal GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 A4G23_RS03040 c76fe16b4ef030b01e0d215094781a36 961 Gene3D G3DSA:3.40.640.10 505 741 8.4E-40 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS03040 c76fe16b4ef030b01e0d215094781a36 961 Gene3D G3DSA:3.40.640.10 94 310 1.7E-17 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS03040 c76fe16b4ef030b01e0d215094781a36 961 SUPERFAMILY SSF53383 478 890 1.85E-97 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS03040 c76fe16b4ef030b01e0d215094781a36 961 SUPERFAMILY SSF53383 932 955 1.85E-97 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS03040 c76fe16b4ef030b01e0d215094781a36 961 TIGRFAM TIGR00461 gcvP: glycine dehydrogenase 20 953 0.0 T 10-11-2016 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 A4G23_RS03040 c76fe16b4ef030b01e0d215094781a36 961 Hamap MF_00711 Glycine dehydrogenase (decarboxylating) [gcvP]. 11 959 25.678 T 10-11-2016 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 A4G23_RS19135 51aee71f82f4bf73b319e287f9663700 209 Pfam PF07336 Putative stress-induced transcription regulator 9 134 3.2E-16 T 10-11-2016 IPR010852 Putative stress-induced transcription regulator A4G23_RS19135 51aee71f82f4bf73b319e287f9663700 209 Gene3D G3DSA:1.10.3300.10 8 185 2.3E-45 T 10-11-2016 IPR023286 ABATE domain A4G23_RS19135 51aee71f82f4bf73b319e287f9663700 209 SUPERFAMILY SSF160904 8 182 2.75E-38 T 10-11-2016 A4G23_RS19135 51aee71f82f4bf73b319e287f9663700 209 Pfam PF11706 CGNR zinc finger 141 183 1.0E-14 T 10-11-2016 IPR021005 Zinc finger, CGNR A4G23_RS14550 b4dc35e1a7eef03dfb4ff9539ed4c585 432 Pfam PF07730 Histidine kinase 226 290 1.6E-18 T 10-11-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4G23_RS14550 b4dc35e1a7eef03dfb4ff9539ed4c585 432 SUPERFAMILY SSF55874 312 424 2.26E-7 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS06820 b00ab50e78be2b9bb6e86ad98eeb8a40 116 SUPERFAMILY SSF55331 2 113 1.12E-22 T 10-11-2016 IPR014347 Tautomerase/MIF superfamily A4G23_RS06820 b00ab50e78be2b9bb6e86ad98eeb8a40 116 Gene3D G3DSA:3.30.429.10 2 113 1.3E-25 T 10-11-2016 A4G23_RS02810 0a79e04ca97721a071ec6a87992190f1 177 Pfam PF00581 Rhodanese-like domain 64 147 1.4E-13 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS02810 0a79e04ca97721a071ec6a87992190f1 177 Gene3D G3DSA:3.40.250.10 52 153 7.9E-21 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS02810 0a79e04ca97721a071ec6a87992190f1 177 SUPERFAMILY SSF52821 49 154 4.71E-24 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS02810 0a79e04ca97721a071ec6a87992190f1 177 SMART SM00450 54 151 1.2E-17 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS07670 c014ebc3db8d3bcdf4ae567530b362fe 642 SUPERFAMILY SSF90123 110 380 8.76E-84 T 10-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A4G23_RS07670 c014ebc3db8d3bcdf4ae567530b362fe 642 SUPERFAMILY SSF90123 25 69 8.76E-84 T 10-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A4G23_RS07670 c014ebc3db8d3bcdf4ae567530b362fe 642 Gene3D G3DSA:1.20.1560.10 111 380 3.8E-86 T 10-11-2016 A4G23_RS07670 c014ebc3db8d3bcdf4ae567530b362fe 642 Gene3D G3DSA:1.20.1560.10 25 77 3.8E-86 T 10-11-2016 A4G23_RS07670 c014ebc3db8d3bcdf4ae567530b362fe 642 Pfam PF00005 ABC transporter 412 563 3.3E-30 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS07670 c014ebc3db8d3bcdf4ae567530b362fe 642 SMART SM00382 420 609 1.1E-15 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS07670 c014ebc3db8d3bcdf4ae567530b362fe 642 SUPERFAMILY SSF52540 388 634 4.78E-88 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS07670 c014ebc3db8d3bcdf4ae567530b362fe 642 Gene3D G3DSA:3.40.50.300 394 627 2.7E-78 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS07670 c014ebc3db8d3bcdf4ae567530b362fe 642 Pfam PF00664 ABC transporter transmembrane region 41 350 1.6E-55 T 10-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A4G23_RS07670 c014ebc3db8d3bcdf4ae567530b362fe 642 ProSitePatterns PS00211 ABC transporters family signature. 535 549 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS05680 6dc55751ae829836632ac372009033ce 334 PIRSF PIRSF000149 1 333 1.4E-135 T 10-11-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4G23_RS05680 6dc55751ae829836632ac372009033ce 334 SUPERFAMILY SSF51735 2 178 1.32E-63 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS05680 6dc55751ae829836632ac372009033ce 334 SMART SM00846 3 153 3.4E-96 T 10-11-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4G23_RS05680 6dc55751ae829836632ac372009033ce 334 Gene3D G3DSA:3.40.50.720 2 161 4.9E-77 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS05680 6dc55751ae829836632ac372009033ce 334 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 325 2.2E-139 T 10-11-2016 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4G23_RS05680 6dc55751ae829836632ac372009033ce 334 SUPERFAMILY SSF55347 153 314 7.74E-71 T 10-11-2016 A4G23_RS05680 6dc55751ae829836632ac372009033ce 334 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 153 1.4E-61 T 10-11-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4G23_RS05680 6dc55751ae829836632ac372009033ce 334 Gene3D G3DSA:3.30.360.10 162 315 2.8E-75 T 10-11-2016 A4G23_RS05680 6dc55751ae829836632ac372009033ce 334 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 158 313 6.4E-69 T 10-11-2016 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4G23_RS05680 6dc55751ae829836632ac372009033ce 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 270 285 6.5E-41 T 10-11-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4G23_RS05680 6dc55751ae829836632ac372009033ce 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 110 123 6.5E-41 T 10-11-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4G23_RS05680 6dc55751ae829836632ac372009033ce 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 147 165 6.5E-41 T 10-11-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4G23_RS05680 6dc55751ae829836632ac372009033ce 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 174 190 6.5E-41 T 10-11-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4G23_RS05680 6dc55751ae829836632ac372009033ce 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 230 247 6.5E-41 T 10-11-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4G23_RS05375 25d98402cd9d5590094110a70c56b82b 233 SUPERFAMILY SSF52833 1 211 4.63E-44 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS05375 25d98402cd9d5590094110a70c56b82b 233 Gene3D G3DSA:3.40.30.10 1 210 3.7E-48 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS05375 25d98402cd9d5590094110a70c56b82b 233 Pfam PF01323 DSBA-like thioredoxin domain 2 205 2.8E-41 T 10-11-2016 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 A4G23_RS01235 206f30bd274bff9c706f1b7b33b3a412 204 Pfam PF04972 BON domain 128 194 2.0E-10 T 10-11-2016 IPR007055 BON domain A4G23_RS01235 206f30bd274bff9c706f1b7b33b3a412 204 Pfam PF00571 CBS domain 6 58 2.2E-12 T 10-11-2016 IPR000644 CBS domain A4G23_RS01235 206f30bd274bff9c706f1b7b33b3a412 204 Pfam PF00571 CBS domain 73 124 4.3E-14 T 10-11-2016 IPR000644 CBS domain A4G23_RS01235 206f30bd274bff9c706f1b7b33b3a412 204 SMART SM00116 13 61 1.8E-8 T 10-11-2016 IPR000644 CBS domain A4G23_RS01235 206f30bd274bff9c706f1b7b33b3a412 204 SMART SM00116 77 125 1.8E-8 T 10-11-2016 IPR000644 CBS domain A4G23_RS01235 206f30bd274bff9c706f1b7b33b3a412 204 Gene3D G3DSA:3.20.20.70 4 155 5.3E-32 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS01235 206f30bd274bff9c706f1b7b33b3a412 204 SMART SM00749 133 196 0.0085 T 10-11-2016 IPR014004 Transport-associated and nodulation domain, bacteria A4G23_RS01235 206f30bd274bff9c706f1b7b33b3a412 204 SUPERFAMILY SSF54631 2 123 3.27E-34 T 10-11-2016 A4G23_RS12165 347735d391c51c6dfe669af28c9a3f7d 195 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 31 190 7.1E-22 T 10-11-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS12165 347735d391c51c6dfe669af28c9a3f7d 195 Pfam PF08281 Sigma-70, region 4 135 187 2.7E-13 T 10-11-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS12165 347735d391c51c6dfe669af28c9a3f7d 195 Gene3D G3DSA:1.10.1740.10 17 122 8.2E-24 T 10-11-2016 A4G23_RS12165 347735d391c51c6dfe669af28c9a3f7d 195 SUPERFAMILY SSF88946 15 119 4.32E-23 T 10-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS12165 347735d391c51c6dfe669af28c9a3f7d 195 Gene3D G3DSA:1.10.10.10 133 192 7.8E-18 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS12165 347735d391c51c6dfe669af28c9a3f7d 195 Pfam PF04542 Sigma-70 region 2 36 103 1.9E-17 T 10-11-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS12165 347735d391c51c6dfe669af28c9a3f7d 195 SUPERFAMILY SSF88659 129 191 1.2E-14 T 10-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS11550 5732fd11a90ffcbd662705cf2437526f 532 SUPERFAMILY SSF52096 269 524 1.27E-74 T 10-11-2016 IPR029045 ClpP/crotonase-like domain A4G23_RS11550 5732fd11a90ffcbd662705cf2437526f 532 Pfam PF01039 Carboxyl transferase domain 48 520 1.3E-132 T 10-11-2016 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4G23_RS11550 5732fd11a90ffcbd662705cf2437526f 532 SUPERFAMILY SSF52096 24 262 1.61E-61 T 10-11-2016 IPR029045 ClpP/crotonase-like domain A4G23_RS11550 5732fd11a90ffcbd662705cf2437526f 532 Gene3D G3DSA:3.90.226.10 30 266 2.0E-60 T 10-11-2016 IPR029045 ClpP/crotonase-like domain A4G23_RS11550 5732fd11a90ffcbd662705cf2437526f 532 Gene3D G3DSA:3.90.226.10 274 521 4.9E-77 T 10-11-2016 IPR029045 ClpP/crotonase-like domain A4G23_RS25410 6facccc86a1bd2620fbcfcc09de9bdd3 230 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 15 214 4.8E-24 T 10-11-2016 IPR013830 SGNH hydrolase-type esterase domain A4G23_RS25410 6facccc86a1bd2620fbcfcc09de9bdd3 230 Gene3D G3DSA:3.40.50.1110 9 223 1.0E-37 T 10-11-2016 IPR013830 SGNH hydrolase-type esterase domain A4G23_RS25410 6facccc86a1bd2620fbcfcc09de9bdd3 230 SUPERFAMILY SSF52266 7 223 1.31E-39 T 10-11-2016 IPR013830 SGNH hydrolase-type esterase domain A4G23_RS04880 ca9298ff0eab626e2d19bfab806b1ebb 368 SUPERFAMILY SSF55120 177 364 2.06E-43 T 10-11-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4G23_RS04880 ca9298ff0eab626e2d19bfab806b1ebb 368 Pfam PF00849 RNA pseudouridylate synthase 193 324 2.7E-23 T 10-11-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4G23_RS04880 ca9298ff0eab626e2d19bfab806b1ebb 368 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 197 355 1.0E-42 T 10-11-2016 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 A4G23_RS04880 ca9298ff0eab626e2d19bfab806b1ebb 368 SUPERFAMILY SSF55174 128 197 2.35E-11 T 10-11-2016 A4G23_RS04880 ca9298ff0eab626e2d19bfab806b1ebb 368 Gene3D G3DSA:3.10.290.10 130 191 4.5E-21 T 10-11-2016 IPR002942 RNA-binding S4 domain GO:0003723 A4G23_RS04880 ca9298ff0eab626e2d19bfab806b1ebb 368 Pfam PF01479 S4 domain 132 174 1.6E-10 T 10-11-2016 IPR002942 RNA-binding S4 domain GO:0003723 A4G23_RS04880 ca9298ff0eab626e2d19bfab806b1ebb 368 SMART SM00363 132 192 4.3E-9 T 10-11-2016 IPR002942 RNA-binding S4 domain GO:0003723 A4G23_RS04880 ca9298ff0eab626e2d19bfab806b1ebb 368 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 230 244 - T 10-11-2016 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 A4G23_RS12605 040bf4b9e71876a0731bd81ef283c421 283 Gene3D G3DSA:1.10.260.40 8 74 5.6E-11 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS12605 040bf4b9e71876a0731bd81ef283c421 283 SMART SM00530 17 72 3.1E-9 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS12605 040bf4b9e71876a0731bd81ef283c421 283 SUPERFAMILY SSF47413 10 73 2.2E-10 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS12605 040bf4b9e71876a0731bd81ef283c421 283 Pfam PF13560 Helix-turn-helix domain 13 69 8.2E-13 T 10-11-2016 A4G23_RS21390 1dbd582aa9a51c2e34c1b826bdb36709 276 SMART SM00020 38 276 4.5E-60 T 10-11-2016 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 A4G23_RS21390 1dbd582aa9a51c2e34c1b826bdb36709 276 Gene3D G3DSA:2.40.10.10 79 140 1.3E-12 T 10-11-2016 A4G23_RS21390 1dbd582aa9a51c2e34c1b826bdb36709 276 Pfam PF00089 Trypsin 39 273 1.6E-49 T 10-11-2016 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 A4G23_RS21390 1dbd582aa9a51c2e34c1b826bdb36709 276 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 72 87 1.2E-10 T 10-11-2016 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 A4G23_RS21390 1dbd582aa9a51c2e34c1b826bdb36709 276 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 135 149 1.2E-10 T 10-11-2016 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 A4G23_RS21390 1dbd582aa9a51c2e34c1b826bdb36709 276 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 230 242 1.2E-10 T 10-11-2016 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 A4G23_RS21390 1dbd582aa9a51c2e34c1b826bdb36709 276 Gene3D G3DSA:2.40.10.10 39 78 2.6E-11 T 10-11-2016 A4G23_RS21390 1dbd582aa9a51c2e34c1b826bdb36709 276 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 231 242 - T 10-11-2016 IPR033116 Serine proteases, trypsin family, serine active site A4G23_RS21390 1dbd582aa9a51c2e34c1b826bdb36709 276 Gene3D G3DSA:2.40.10.10 141 273 5.0E-37 T 10-11-2016 A4G23_RS21390 1dbd582aa9a51c2e34c1b826bdb36709 276 SUPERFAMILY SSF50494 16 273 1.19E-58 T 10-11-2016 IPR009003 Peptidase S1, PA clan A4G23_RS01870 84aceb56529a2720a0841b2c916985dd 346 PRINTS PR00502 NUDIX hydrolase family signature 226 240 3.7E-7 T 10-11-2016 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A4G23_RS01870 84aceb56529a2720a0841b2c916985dd 346 PRINTS PR00502 NUDIX hydrolase family signature 240 255 3.7E-7 T 10-11-2016 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A4G23_RS01870 84aceb56529a2720a0841b2c916985dd 346 Pfam PF00293 NUDIX domain 202 323 5.1E-17 T 10-11-2016 IPR000086 NUDIX hydrolase domain GO:0016787 A4G23_RS01870 84aceb56529a2720a0841b2c916985dd 346 SUPERFAMILY SSF52540 2 181 1.25E-19 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS01870 84aceb56529a2720a0841b2c916985dd 346 SUPERFAMILY SSF55811 192 330 5.96E-23 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS01870 84aceb56529a2720a0841b2c916985dd 346 Gene3D G3DSA:3.90.79.10 202 332 5.3E-23 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS01870 84aceb56529a2720a0841b2c916985dd 346 Gene3D G3DSA:3.40.50.300 2 183 3.2E-10 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS01870 84aceb56529a2720a0841b2c916985dd 346 ProSitePatterns PS00893 Nudix box signature. 231 252 - T 10-11-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A4G23_RS01870 84aceb56529a2720a0841b2c916985dd 346 Pfam PF13671 AAA domain 3 131 2.4E-7 T 10-11-2016 A4G23_RS14815 8d1bbd7c795058e81aafbeca589af95e 338 Gene3D G3DSA:3.40.50.300 6 231 8.3E-36 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS14815 8d1bbd7c795058e81aafbeca589af95e 338 SUPERFAMILY SSF52540 5 225 1.39E-29 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS14815 8d1bbd7c795058e81aafbeca589af95e 338 Pfam PF02374 Anion-transporting ATPase 6 171 2.0E-18 T 10-11-2016 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 A4G23_RS06230 dedb0dc6f0aa6d90a2a4befeaa476573 406 Gene3D G3DSA:3.40.50.1440 11 211 3.7E-92 T 10-11-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A4G23_RS06230 dedb0dc6f0aa6d90a2a4befeaa476573 406 Pfam PF12327 FtsZ family, C-terminal domain 219 313 4.5E-35 T 10-11-2016 IPR024757 Cell division protein FtsZ, C-terminal A4G23_RS06230 dedb0dc6f0aa6d90a2a4befeaa476573 406 SUPERFAMILY SSF55307 201 315 6.18E-44 T 10-11-2016 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 A4G23_RS06230 dedb0dc6f0aa6d90a2a4befeaa476573 406 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 11 170 4.1E-38 T 10-11-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A4G23_RS06230 dedb0dc6f0aa6d90a2a4befeaa476573 406 ProSitePatterns PS01135 FtsZ protein signature 2. 94 115 - T 10-11-2016 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 A4G23_RS06230 dedb0dc6f0aa6d90a2a4befeaa476573 406 Gene3D G3DSA:3.30.1330.20 212 314 3.5E-49 T 10-11-2016 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-983189 A4G23_RS06230 dedb0dc6f0aa6d90a2a4befeaa476573 406 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 6 350 38.957 T 10-11-2016 IPR000158 Cell division protein FtsZ GO:0005525 A4G23_RS06230 dedb0dc6f0aa6d90a2a4befeaa476573 406 SMART SM00864 10 202 2.8E-110 T 10-11-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A4G23_RS06230 dedb0dc6f0aa6d90a2a4befeaa476573 406 SMART SM00865 204 321 3.0E-57 T 10-11-2016 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-983189 A4G23_RS06230 dedb0dc6f0aa6d90a2a4befeaa476573 406 PRINTS PR00423 Cell division protein FtsZ signature 95 115 1.1E-51 T 10-11-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A4G23_RS06230 dedb0dc6f0aa6d90a2a4befeaa476573 406 PRINTS PR00423 Cell division protein FtsZ signature 209 230 1.1E-51 T 10-11-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A4G23_RS06230 dedb0dc6f0aa6d90a2a4befeaa476573 406 PRINTS PR00423 Cell division protein FtsZ signature 186 208 1.1E-51 T 10-11-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A4G23_RS06230 dedb0dc6f0aa6d90a2a4befeaa476573 406 PRINTS PR00423 Cell division protein FtsZ signature 123 144 1.1E-51 T 10-11-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A4G23_RS06230 dedb0dc6f0aa6d90a2a4befeaa476573 406 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 7 315 3.8E-128 T 10-11-2016 IPR000158 Cell division protein FtsZ GO:0005525 A4G23_RS06230 dedb0dc6f0aa6d90a2a4befeaa476573 406 SUPERFAMILY SSF52490 9 205 9.03E-68 T 10-11-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A4G23_RS06230 dedb0dc6f0aa6d90a2a4befeaa476573 406 ProSitePatterns PS01134 FtsZ protein signature 1. 41 75 - T 10-11-2016 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 A4G23_RS26385 f61a48ce081cce6db4ccd1ad9213481a 327 Gene3D G3DSA:3.30.470.20 118 300 7.8E-10 T 10-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 A4G23_RS26385 f61a48ce081cce6db4ccd1ad9213481a 327 SUPERFAMILY SSF56059 127 306 1.34E-25 T 10-11-2016 A4G23_RS26385 f61a48ce081cce6db4ccd1ad9213481a 327 Pfam PF02955 Prokaryotic glutathione synthetase, ATP-grasp domain 141 203 2.6E-5 T 10-11-2016 IPR004218 Prokaryotic glutathione synthetase, ATP-binding GO:0004363|GO:0005524|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 A4G23_RS08275 afbd526f242e2e9b95bb68fb513bae32 137 SMART SM00562 2 137 3.0E-76 T 10-11-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A4G23_RS08275 afbd526f242e2e9b95bb68fb513bae32 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 5 27 1.1E-41 T 10-11-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A4G23_RS08275 afbd526f242e2e9b95bb68fb513bae32 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 70 87 1.1E-41 T 10-11-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A4G23_RS08275 afbd526f242e2e9b95bb68fb513bae32 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 50 69 1.1E-41 T 10-11-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A4G23_RS08275 afbd526f242e2e9b95bb68fb513bae32 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 1.1E-41 T 10-11-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A4G23_RS08275 afbd526f242e2e9b95bb68fb513bae32 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 1.1E-41 T 10-11-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A4G23_RS08275 afbd526f242e2e9b95bb68fb513bae32 137 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 114 122 - T 10-11-2016 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A4G23_RS08275 afbd526f242e2e9b95bb68fb513bae32 137 Pfam PF00334 Nucleoside diphosphate kinase 3 134 4.4E-52 T 10-11-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A4G23_RS08275 afbd526f242e2e9b95bb68fb513bae32 137 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 2 136 32.327 T 10-11-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A4G23_RS08275 afbd526f242e2e9b95bb68fb513bae32 137 Gene3D G3DSA:3.30.70.141 2 134 4.5E-56 T 10-11-2016 A4G23_RS08275 afbd526f242e2e9b95bb68fb513bae32 137 SUPERFAMILY SSF54919 1 135 2.49E-52 T 10-11-2016 A4G23_RS16735 05e905e949700a55748efcb6419b1a92 134 Pfam PF00411 Ribosomal protein S11 24 133 1.3E-48 T 10-11-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 A4G23_RS16735 05e905e949700a55748efcb6419b1a92 134 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 6 134 34.428 T 10-11-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 A4G23_RS16735 05e905e949700a55748efcb6419b1a92 134 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 15 131 1.7E-59 T 10-11-2016 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS16735 05e905e949700a55748efcb6419b1a92 134 SUPERFAMILY SSF53137 19 134 4.8E-50 T 10-11-2016 A4G23_RS16735 05e905e949700a55748efcb6419b1a92 134 ProSitePatterns PS00054 Ribosomal protein S11 signature. 102 124 - T 10-11-2016 IPR018102 Ribosomal S11, conserved site A4G23_RS16735 05e905e949700a55748efcb6419b1a92 134 PIRSF PIRSF002131 4 134 3.6E-54 T 10-11-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 A4G23_RS16735 05e905e949700a55748efcb6419b1a92 134 Gene3D G3DSA:3.30.420.80 11 134 2.4E-58 T 10-11-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 A4G23_RS13600 2b576020c3b7af9880598ed7d214bb99 191 Hamap MF_00984 Single-stranded DNA-binding protein. 4 113 30.15 T 10-11-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 A4G23_RS13600 2b576020c3b7af9880598ed7d214bb99 191 Pfam PF00436 Single-strand binding protein family 7 106 8.7E-30 T 10-11-2016 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 A4G23_RS13600 2b576020c3b7af9880598ed7d214bb99 191 Gene3D G3DSA:2.40.50.140 4 116 5.5E-41 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS13600 2b576020c3b7af9880598ed7d214bb99 191 SUPERFAMILY SSF50249 6 191 9.79E-45 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS13600 2b576020c3b7af9880598ed7d214bb99 191 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 6 129 1.5E-29 T 10-11-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 A4G23_RS26175 c620ee2c19043f5e3c8a59d98ff3668d 310 SUPERFAMILY SSF50370 194 309 3.13E-15 T 10-11-2016 IPR000772 Ricin B, lectin domain A4G23_RS26175 c620ee2c19043f5e3c8a59d98ff3668d 310 SMART SM00530 19 74 5.4E-4 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS26175 c620ee2c19043f5e3c8a59d98ff3668d 310 Pfam PF00652 Ricin-type beta-trefoil lectin domain 196 309 1.4E-10 T 10-11-2016 IPR000772 Ricin B, lectin domain A4G23_RS26175 c620ee2c19043f5e3c8a59d98ff3668d 310 Gene3D G3DSA:2.80.10.50 195 309 2.8E-13 T 10-11-2016 A4G23_RS26175 c620ee2c19043f5e3c8a59d98ff3668d 310 Pfam PF13560 Helix-turn-helix domain 15 73 6.3E-11 T 10-11-2016 A4G23_RS26175 c620ee2c19043f5e3c8a59d98ff3668d 310 SUPERFAMILY SSF47413 14 71 1.16E-6 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS26175 c620ee2c19043f5e3c8a59d98ff3668d 310 Gene3D G3DSA:1.10.260.40 14 71 1.3E-7 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS12055 4ece6a200beb50eae228991be824b592 287 Gene3D G3DSA:3.20.20.70 1 284 5.4E-82 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS12055 4ece6a200beb50eae228991be824b592 287 Pfam PF01116 Fructose-bisphosphate aldolase class-II 5 281 9.2E-76 T 10-11-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A4G23_RS12055 4ece6a200beb50eae228991be824b592 287 PIRSF PIRSF001359 1 287 1.2E-64 T 10-11-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A4G23_RS12055 4ece6a200beb50eae228991be824b592 287 SUPERFAMILY SSF51569 2 281 1.36E-77 T 10-11-2016 A4G23_RS20045 c33f36e49856dce75e72e8076fb7679b 108 Pfam PF04248 Domain of unknown function (DUF427) 17 104 6.0E-31 T 10-11-2016 IPR007361 Domain of unknown function DUF427 A4G23_RS14725 9ed9ccc00eaaf5439ee14c4454256237 199 Pfam PF00633 Helix-hairpin-helix motif 2 27 3.5E-6 T 10-11-2016 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 A4G23_RS14725 9ed9ccc00eaaf5439ee14c4454256237 199 Pfam PF02132 RecR protein 38 77 8.6E-17 T 10-11-2016 IPR023628 Recombination protein RecR, C4-type zinc finger A4G23_RS14725 9ed9ccc00eaaf5439ee14c4454256237 199 Hamap MF_00017 Recombination protein RecR [recR]. 1 197 108.641 T 10-11-2016 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 A4G23_RS14725 9ed9ccc00eaaf5439ee14c4454256237 199 ProSitePatterns PS01300 RecR protein signature. 56 77 - T 10-11-2016 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 A4G23_RS14725 9ed9ccc00eaaf5439ee14c4454256237 199 SMART SM00493 79 164 8.2E-17 T 10-11-2016 IPR006171 Toprim domain A4G23_RS14725 9ed9ccc00eaaf5439ee14c4454256237 199 Pfam PF13662 Toprim domain 80 170 5.7E-26 T 10-11-2016 IPR006171 Toprim domain A4G23_RS14725 9ed9ccc00eaaf5439ee14c4454256237 199 TIGRFAM TIGR00615 recR: recombination protein RecR 2 195 5.3E-85 T 10-11-2016 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 A4G23_RS14725 9ed9ccc00eaaf5439ee14c4454256237 199 Gene3D G3DSA:3.40.50.140 115 169 7.5E-6 T 10-11-2016 IPR006171 Toprim domain A4G23_RS14725 9ed9ccc00eaaf5439ee14c4454256237 199 SUPERFAMILY SSF111304 3 197 3.92E-75 T 10-11-2016 IPR023627 Recombination protein RecR A4G23_RS00715 9e729e362b4c52754d70c32ff6a10e32 336 SMART SM00481 98 177 1.7E-17 T 10-11-2016 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 A4G23_RS00715 9e729e362b4c52754d70c32ff6a10e32 336 SUPERFAMILY SSF89550 97 329 1.31E-48 T 10-11-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A4G23_RS00715 9e729e362b4c52754d70c32ff6a10e32 336 Gene3D G3DSA:1.10.8.310 2 79 2.1E-8 T 10-11-2016 IPR027420 DNA polymerase beta, N-terminal domain A4G23_RS00715 9e729e362b4c52754d70c32ff6a10e32 336 Gene3D G3DSA:3.20.20.140 97 330 1.1E-47 T 10-11-2016 A4G23_RS00715 9e729e362b4c52754d70c32ff6a10e32 336 PIRSF PIRSF036978 1 333 6.5E-172 T 10-11-2016 IPR017078 Uncharacterised conserved protein UCP036978, histidinol phosphatase-related hydrolase, SCO0789 A4G23_RS00715 9e729e362b4c52754d70c32ff6a10e32 336 Pfam PF14716 Helix-hairpin-helix domain 1 66 1.1E-12 T 10-11-2016 IPR010996 DNA polymerase beta-like, N-terminal domain A4G23_RS00715 9e729e362b4c52754d70c32ff6a10e32 336 SUPERFAMILY SSF47802 2 79 4.06E-10 T 10-11-2016 IPR010996 DNA polymerase beta-like, N-terminal domain A4G23_RS04775 96774f1b92174a09f43eaa241a9f8ed5 339 Gene3D G3DSA:1.20.144.10 68 222 6.6E-17 T 10-11-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A4G23_RS04775 96774f1b92174a09f43eaa241a9f8ed5 339 SMART SM00014 104 220 2.7E-8 T 10-11-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A4G23_RS04775 96774f1b92174a09f43eaa241a9f8ed5 339 SUPERFAMILY SSF48317 37 236 7.06E-27 T 10-11-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A4G23_RS04775 96774f1b92174a09f43eaa241a9f8ed5 339 Pfam PF01569 PAP2 superfamily 107 222 7.5E-19 T 10-11-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A4G23_RS00320 112fde3f82827fb4901a3838bebff94f 410 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 196 384 8.7E-33 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS00320 112fde3f82827fb4901a3838bebff94f 410 SMART SM00331 169 384 4.4E-15 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS00320 112fde3f82827fb4901a3838bebff94f 410 SUPERFAMILY SSF81606 186 331 6.93E-10 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS10800 b8e20d298bef2d104bdcf4065d0c2fe7 339 Gene3D G3DSA:3.40.50.1170 3 196 3.0E-48 T 10-11-2016 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 A4G23_RS10800 b8e20d298bef2d104bdcf4065d0c2fe7 339 PIRSF PIRSF001220 1 326 3.7E-75 T 10-11-2016 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 A4G23_RS10800 b8e20d298bef2d104bdcf4065d0c2fe7 339 Pfam PF00710 Asparaginase, N-terminal 3 188 1.4E-46 T 10-11-2016 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 A4G23_RS10800 b8e20d298bef2d104bdcf4065d0c2fe7 339 PIRSF PIRSF500176 1 320 8.3E-79 T 10-11-2016 A4G23_RS10800 b8e20d298bef2d104bdcf4065d0c2fe7 339 SMART SM00870 3 317 2.4E-88 T 10-11-2016 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 A4G23_RS10800 b8e20d298bef2d104bdcf4065d0c2fe7 339 SUPERFAMILY SSF53774 2 316 1.05E-77 T 10-11-2016 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 A4G23_RS10800 b8e20d298bef2d104bdcf4065d0c2fe7 339 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 6 14 - T 10-11-2016 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 A4G23_RS10800 b8e20d298bef2d104bdcf4065d0c2fe7 339 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 79 89 - T 10-11-2016 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 A4G23_RS10800 b8e20d298bef2d104bdcf4065d0c2fe7 339 Gene3D G3DSA:3.40.50.40 206 313 1.1E-21 T 10-11-2016 IPR027473 L-asparaginase, C-terminal domain Reactome: R-HSA-70614 A4G23_RS10800 b8e20d298bef2d104bdcf4065d0c2fe7 339 PRINTS PR00139 Asparaginase/glutaminase family signature 78 96 9.3E-18 T 10-11-2016 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 A4G23_RS10800 b8e20d298bef2d104bdcf4065d0c2fe7 339 PRINTS PR00139 Asparaginase/glutaminase family signature 253 271 9.3E-18 T 10-11-2016 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 A4G23_RS10800 b8e20d298bef2d104bdcf4065d0c2fe7 339 PRINTS PR00139 Asparaginase/glutaminase family signature 4 15 9.3E-18 T 10-11-2016 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 A4G23_RS23925 222455d65f1ec5a715718928ff1a837c 229 ProSitePatterns PS00622 LuxR-type HTH domain signature. 177 204 - T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS23925 222455d65f1ec5a715718928ff1a837c 229 SMART SM00448 3 116 3.2E-29 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS23925 222455d65f1ec5a715718928ff1a837c 229 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 193 4.8E-11 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS23925 222455d65f1ec5a715718928ff1a837c 229 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 177 4.8E-11 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS23925 222455d65f1ec5a715718928ff1a837c 229 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 193 205 4.8E-11 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS23925 222455d65f1ec5a715718928ff1a837c 229 Pfam PF00196 Bacterial regulatory proteins, luxR family 163 216 2.3E-13 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS23925 222455d65f1ec5a715718928ff1a837c 229 Pfam PF00072 Response regulator receiver domain 6 116 1.4E-26 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS23925 222455d65f1ec5a715718928ff1a837c 229 SUPERFAMILY SSF46894 151 224 5.1E-19 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS23925 222455d65f1ec5a715718928ff1a837c 229 Gene3D G3DSA:3.40.50.2300 1 124 4.9E-35 T 10-11-2016 A4G23_RS23925 222455d65f1ec5a715718928ff1a837c 229 SUPERFAMILY SSF52172 2 134 1.01E-32 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS23925 222455d65f1ec5a715718928ff1a837c 229 Gene3D G3DSA:1.10.10.10 125 224 7.9E-28 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS23925 222455d65f1ec5a715718928ff1a837c 229 SMART SM00421 160 217 1.8E-18 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS25340 bf8c2a21da65e84958c47dab5a77db6d 340 Gene3D G3DSA:3.40.50.720 165 281 1.2E-21 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS25340 bf8c2a21da65e84958c47dab5a77db6d 340 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 24 129 8.6E-25 T 10-11-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A4G23_RS25340 bf8c2a21da65e84958c47dab5a77db6d 340 SUPERFAMILY SSF51735 139 300 3.18E-24 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS25340 bf8c2a21da65e84958c47dab5a77db6d 340 Pfam PF00107 Zinc-binding dehydrogenase 171 298 5.6E-15 T 10-11-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A4G23_RS25340 bf8c2a21da65e84958c47dab5a77db6d 340 SUPERFAMILY SSF50129 1 170 2.89E-44 T 10-11-2016 IPR011032 GroES-like A4G23_RS25340 bf8c2a21da65e84958c47dab5a77db6d 340 Gene3D G3DSA:3.90.180.10 1 164 2.9E-48 T 10-11-2016 IPR011032 GroES-like A4G23_RS16235 85e900fecdc0275cdf5c21633889fa17 287 Hamap MF_00188 Protease HtpX [htpX]. 7 282 28.045 T 10-11-2016 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 A4G23_RS16235 85e900fecdc0275cdf5c21633889fa17 287 Gene3D G3DSA:3.30.2010.10 59 149 5.4E-31 T 10-11-2016 A4G23_RS16235 85e900fecdc0275cdf5c21633889fa17 287 Pfam PF01435 Peptidase family M48 68 282 1.1E-35 T 10-11-2016 IPR001915 Peptidase M48 GO:0004222|GO:0006508 A4G23_RS10960 d66a1387baf7c33a216088c5ef79827f 349 SUPERFAMILY SSF46785 6 64 1.11E-9 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS10960 d66a1387baf7c33a216088c5ef79827f 349 Pfam PF13280 WYL domain 142 333 2.8E-26 T 10-11-2016 IPR026881 WYL domain A4G23_RS10960 d66a1387baf7c33a216088c5ef79827f 349 Gene3D G3DSA:1.10.10.10 7 66 1.7E-17 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS10960 d66a1387baf7c33a216088c5ef79827f 349 Pfam PF08279 HTH domain 7 62 3.2E-14 T 10-11-2016 IPR013196 Helix-turn-helix, type 11 A4G23_RS23165 7d59607f1b2751eb1d9143dbb1e798a4 371 Pfam PF13379 NMT1-like family 54 290 8.7E-27 T 10-11-2016 A4G23_RS23165 7d59607f1b2751eb1d9143dbb1e798a4 371 SUPERFAMILY SSF53850 54 285 8.08E-34 T 10-11-2016 A4G23_RS23165 7d59607f1b2751eb1d9143dbb1e798a4 371 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 56 348 8.8E-50 T 10-11-2016 IPR010067 Aliphatic sulfonates-binding protein GO:0006790|GO:0006810|GO:0016020 A4G23_RS23165 7d59607f1b2751eb1d9143dbb1e798a4 371 Gene3D G3DSA:3.40.190.10 139 270 1.7E-14 T 10-11-2016 A4G23_RS02535 9cd34259b0117f83bc1e0e4d64275da8 280 Pfam PF03631 Virulence factor BrkB 27 255 1.9E-9 T 10-11-2016 IPR017039 Virulence factor BrkB A4G23_RS18730 a82fb5b7bad95c1cad4158ae2b505692 262 Pfam PF13531 Bacterial extracellular solute-binding protein 45 260 1.4E-39 T 10-11-2016 A4G23_RS18730 a82fb5b7bad95c1cad4158ae2b505692 262 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 50 255 1.6E-35 T 10-11-2016 IPR005950 Molybdenum ABC transporter, periplasmic binding protein GO:0015412|GO:0015689|GO:0030288 A4G23_RS18730 a82fb5b7bad95c1cad4158ae2b505692 262 SUPERFAMILY SSF53850 44 262 2.06E-48 T 10-11-2016 A4G23_RS18730 a82fb5b7bad95c1cad4158ae2b505692 262 Gene3D G3DSA:3.40.190.10 44 169 2.5E-31 T 10-11-2016 A4G23_RS18730 a82fb5b7bad95c1cad4158ae2b505692 262 PIRSF PIRSF004846 2 262 5.0E-59 T 10-11-2016 IPR005950 Molybdenum ABC transporter, periplasmic binding protein GO:0015412|GO:0015689|GO:0030288 A4G23_RS12675 699291990c775c837de3431efd58d114 548 SMART SM00422 7 77 3.6E-8 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS12675 699291990c775c837de3431efd58d114 548 Gene3D G3DSA:1.10.1660.10 6 101 6.0E-19 T 10-11-2016 A4G23_RS12675 699291990c775c837de3431efd58d114 548 SUPERFAMILY SSF46955 6 104 1.47E-16 T 10-11-2016 IPR009061 Putative DNA-binding domain A4G23_RS12675 699291990c775c837de3431efd58d114 548 Pfam PF13411 MerR HTH family regulatory protein 7 76 6.7E-11 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS12675 699291990c775c837de3431efd58d114 548 Gene3D G3DSA:3.10.150.10 122 237 9.6E-12 T 10-11-2016 A4G23_RS12675 699291990c775c837de3431efd58d114 548 Pfam PF02767 DNA polymerase III beta subunit, central domain 123 235 2.6E-8 T 10-11-2016 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4G23_RS12675 699291990c775c837de3431efd58d114 548 SUPERFAMILY SSF55979 121 235 1.33E-8 T 10-11-2016 A4G23_RS04655 4782920bdcb68b1ef3c7c99ad6607e31 463 Gene3D G3DSA:3.40.309.10 259 436 2.7E-55 T 10-11-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 A4G23_RS04655 4782920bdcb68b1ef3c7c99ad6607e31 463 Pfam PF00171 Aldehyde dehydrogenase family 13 460 5.5E-156 T 10-11-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A4G23_RS04655 4782920bdcb68b1ef3c7c99ad6607e31 463 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 244 251 - T 10-11-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 A4G23_RS04655 4782920bdcb68b1ef3c7c99ad6607e31 463 Gene3D G3DSA:3.40.605.10 6 258 1.1E-86 T 10-11-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A4G23_RS04655 4782920bdcb68b1ef3c7c99ad6607e31 463 SUPERFAMILY SSF53720 4 461 1.7E-150 T 10-11-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A4G23_RS09350 9a86b1e61ccd94e7abd424334905ed87 201 Pfam PF08044 Domain of unknown function (DUF1707) 1 53 5.7E-24 T 10-11-2016 IPR012551 Protein of unknown function DUF1707 A4G23_RS23060 2fdb1ccb7ceb7a059de3ef6eac8cf9d0 290 SUPERFAMILY SSF46785 1 82 3.74E-15 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS23060 2fdb1ccb7ceb7a059de3ef6eac8cf9d0 290 Gene3D G3DSA:3.40.190.10 104 179 4.5E-6 T 10-11-2016 A4G23_RS23060 2fdb1ccb7ceb7a059de3ef6eac8cf9d0 290 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 59 2.9E-14 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS23060 2fdb1ccb7ceb7a059de3ef6eac8cf9d0 290 Gene3D G3DSA:3.40.190.10 180 264 3.2E-14 T 10-11-2016 A4G23_RS23060 2fdb1ccb7ceb7a059de3ef6eac8cf9d0 290 Gene3D G3DSA:1.10.10.10 1 80 3.6E-18 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS23060 2fdb1ccb7ceb7a059de3ef6eac8cf9d0 290 SUPERFAMILY SSF53850 88 277 2.17E-14 T 10-11-2016 A4G23_RS23060 2fdb1ccb7ceb7a059de3ef6eac8cf9d0 290 Pfam PF03466 LysR substrate binding domain 86 280 2.4E-13 T 10-11-2016 IPR005119 LysR, substrate-binding A4G23_RS18775 4e0c1e2ad28c2b421abc07de7759fcba 727 Gene3D G3DSA:1.10.150.80 648 712 2.3E-9 T 10-11-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 A4G23_RS18775 4e0c1e2ad28c2b421abc07de7759fcba 727 Gene3D G3DSA:3.40.50.300 503 586 4.1E-55 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS18775 4e0c1e2ad28c2b421abc07de7759fcba 727 Gene3D G3DSA:3.40.50.300 298 411 4.1E-55 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS18775 4e0c1e2ad28c2b421abc07de7759fcba 727 Pfam PF00570 HRDC domain 649 714 1.3E-17 T 10-11-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 A4G23_RS18775 4e0c1e2ad28c2b421abc07de7759fcba 727 SUPERFAMILY SSF47819 638 718 5.01E-18 T 10-11-2016 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 A4G23_RS18775 4e0c1e2ad28c2b421abc07de7759fcba 727 SUPERFAMILY SSF52540 20 586 2.18E-120 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS18775 4e0c1e2ad28c2b421abc07de7759fcba 727 Pfam PF00580 UvrD/REP helicase N-terminal domain 24 286 3.2E-45 T 10-11-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 A4G23_RS18775 4e0c1e2ad28c2b421abc07de7759fcba 727 SMART SM00341 645 725 7.0E-11 T 10-11-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 A4G23_RS18775 4e0c1e2ad28c2b421abc07de7759fcba 727 Pfam PF13361 UvrD-like helicase C-terminal domain 294 417 3.7E-15 T 10-11-2016 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 A4G23_RS18775 4e0c1e2ad28c2b421abc07de7759fcba 727 Pfam PF13361 UvrD-like helicase C-terminal domain 458 566 2.1E-23 T 10-11-2016 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 A4G23_RS18775 4e0c1e2ad28c2b421abc07de7759fcba 727 Gene3D G3DSA:3.40.50.300 23 292 5.3E-66 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS06315 8f5929c9a33a3261dde166b59fcb4234 354 SUPERFAMILY SSF52540 148 256 6.3E-21 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS06315 8f5929c9a33a3261dde166b59fcb4234 354 SUPERFAMILY SSF52540 20 120 6.3E-21 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS06315 8f5929c9a33a3261dde166b59fcb4234 354 Pfam PF00005 ABC transporter 39 199 2.3E-9 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS06315 8f5929c9a33a3261dde166b59fcb4234 354 Gene3D G3DSA:3.40.50.300 18 230 2.9E-22 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS06465 4304b5ad015ce7b1c3ac38c007c36f53 149 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 4 144 2.7E-15 T 10-11-2016 IPR019587 Polyketide cyclase/dehydrase A4G23_RS06465 4304b5ad015ce7b1c3ac38c007c36f53 149 SUPERFAMILY SSF55961 1 148 6.22E-32 T 10-11-2016 A4G23_RS06465 4304b5ad015ce7b1c3ac38c007c36f53 149 Gene3D G3DSA:3.30.530.20 4 146 1.4E-17 T 10-11-2016 IPR023393 START-like domain A4G23_RS14700 1783c2ee4a93763fe98f89728afc5081 441 Pfam PF00202 Aminotransferase class-III 24 431 1.1E-95 T 10-11-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4G23_RS14700 1783c2ee4a93763fe98f89728afc5081 441 Gene3D G3DSA:3.90.1150.10 309 432 1.7E-32 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS14700 1783c2ee4a93763fe98f89728afc5081 441 Gene3D G3DSA:3.40.640.10 56 308 1.2E-81 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS14700 1783c2ee4a93763fe98f89728afc5081 441 SUPERFAMILY SSF53383 4 431 2.66E-118 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS14700 1783c2ee4a93763fe98f89728afc5081 441 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 236 273 - T 10-11-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4G23_RS15620 1180d559bdb3cb0bb3f2819a5865397d 295 Pfam PF06971 Putative DNA-binding protein N-terminus 16 63 4.7E-19 T 10-11-2016 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 A4G23_RS15620 1180d559bdb3cb0bb3f2819a5865397d 295 SMART SM00881 89 190 1.2E-18 T 10-11-2016 IPR003781 CoA-binding GO:0048037 A4G23_RS15620 1180d559bdb3cb0bb3f2819a5865397d 295 SUPERFAMILY SSF46785 17 89 1.63E-18 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS15620 1180d559bdb3cb0bb3f2819a5865397d 295 Gene3D G3DSA:1.10.10.10 15 85 3.0E-30 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS15620 1180d559bdb3cb0bb3f2819a5865397d 295 Hamap MF_01131 Redox-sensing transcriptional repressor Rex [rex]. 11 219 36.537 T 10-11-2016 IPR022876 Redox-sensing transcriptional repressor Rex GO:0005737|GO:0045892|GO:0051775 A4G23_RS15620 1180d559bdb3cb0bb3f2819a5865397d 295 SUPERFAMILY SSF51735 93 214 3.86E-27 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS15620 1180d559bdb3cb0bb3f2819a5865397d 295 Pfam PF02629 CoA binding domain 91 188 9.2E-20 T 10-11-2016 IPR003781 CoA-binding GO:0048037 A4G23_RS15620 1180d559bdb3cb0bb3f2819a5865397d 295 Gene3D G3DSA:3.40.50.720 88 220 2.5E-49 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS24030 885ee4157a34d15303406bea6acad637 397 Pfam PF01494 FAD binding domain 7 341 2.5E-13 T 10-11-2016 IPR002938 FAD-binding domain GO:0071949 A4G23_RS24030 885ee4157a34d15303406bea6acad637 397 SUPERFAMILY SSF51905 267 371 1.53E-57 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS24030 885ee4157a34d15303406bea6acad637 397 SUPERFAMILY SSF51905 7 170 1.53E-57 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS24030 885ee4157a34d15303406bea6acad637 397 Gene3D G3DSA:3.50.50.60 268 347 1.3E-32 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS24030 885ee4157a34d15303406bea6acad637 397 Gene3D G3DSA:3.50.50.60 7 176 1.3E-32 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS24030 885ee4157a34d15303406bea6acad637 397 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 295 311 5.1E-15 T 10-11-2016 A4G23_RS24030 885ee4157a34d15303406bea6acad637 397 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 149 164 5.1E-15 T 10-11-2016 A4G23_RS24030 885ee4157a34d15303406bea6acad637 397 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 280 295 5.1E-15 T 10-11-2016 A4G23_RS24030 885ee4157a34d15303406bea6acad637 397 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 5.1E-15 T 10-11-2016 A4G23_RS12390 bf3e244c1f32667f6b9ec68596902584 327 Gene3D G3DSA:2.40.30.110 247 325 9.9E-4 T 10-11-2016 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 A4G23_RS12390 bf3e244c1f32667f6b9ec68596902584 327 Pfam PF01571 Aminomethyltransferase folate-binding domain 26 146 1.3E-19 T 10-11-2016 IPR006222 Glycine cleavage T-protein-like, N-terminal A4G23_RS12390 bf3e244c1f32667f6b9ec68596902584 327 SUPERFAMILY SSF101790 248 317 5.89E-5 T 10-11-2016 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain A4G23_RS12390 bf3e244c1f32667f6b9ec68596902584 327 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 191 255 1.5E-21 T 10-11-2016 IPR017703 YgfZ/GcvT conserved site A4G23_RS12390 bf3e244c1f32667f6b9ec68596902584 327 Gene3D G3DSA:3.30.70.1400 51 136 1.1E-12 T 10-11-2016 A4G23_RS12390 bf3e244c1f32667f6b9ec68596902584 327 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 229 315 1.4E-8 T 10-11-2016 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 A4G23_RS12390 bf3e244c1f32667f6b9ec68596902584 327 SUPERFAMILY SSF103025 27 245 2.35E-55 T 10-11-2016 A4G23_RS01190 a819ddd1080b5f646de816864be57e0e 918 SUPERFAMILY SSF103190 59 186 2.24E-31 T 10-11-2016 IPR029151 Periplasmic sensor domain-like A4G23_RS01190 a819ddd1080b5f646de816864be57e0e 918 Pfam PF13188 PAS domain 232 287 2.0E-7 T 10-11-2016 IPR000014 PAS domain A4G23_RS01190 a819ddd1080b5f646de816864be57e0e 918 Pfam PF13581 Histidine kinase-like ATPase domain 783 889 5.5E-10 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS01190 a819ddd1080b5f646de816864be57e0e 918 Gene3D G3DSA:3.30.450.20 227 331 6.6E-8 T 10-11-2016 A4G23_RS01190 a819ddd1080b5f646de816864be57e0e 918 Gene3D G3DSA:3.30.450.20 51 188 2.1E-42 T 10-11-2016 A4G23_RS01190 a819ddd1080b5f646de816864be57e0e 918 SMART SM00065 351 526 3.7E-8 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS01190 a819ddd1080b5f646de816864be57e0e 918 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 571 768 2.3E-53 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS01190 a819ddd1080b5f646de816864be57e0e 918 SMART SM00091 230 295 0.0011 T 10-11-2016 IPR000014 PAS domain A4G23_RS01190 a819ddd1080b5f646de816864be57e0e 918 SUPERFAMILY SSF55785 226 330 1.92E-7 T 10-11-2016 IPR000014 PAS domain A4G23_RS01190 a819ddd1080b5f646de816864be57e0e 918 SMART SM00331 544 768 1.4E-40 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS01190 a819ddd1080b5f646de816864be57e0e 918 SUPERFAMILY SSF55874 812 890 4.12E-7 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS01190 a819ddd1080b5f646de816864be57e0e 918 Pfam PF01590 GAF domain 424 516 1.8E-8 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS01190 a819ddd1080b5f646de816864be57e0e 918 Gene3D G3DSA:3.30.450.40 350 524 6.6E-37 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS01190 a819ddd1080b5f646de816864be57e0e 918 Pfam PF17203 Single cache domain 3 58 187 2.5E-25 T 10-11-2016 IPR033463 Single cache domain 3 A4G23_RS01190 a819ddd1080b5f646de816864be57e0e 918 SUPERFAMILY SSF55781 425 527 4.36E-15 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS01190 a819ddd1080b5f646de816864be57e0e 918 SUPERFAMILY SSF81606 558 767 4.97E-10 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS27055 f29b827004e9bcb0a0d5b0a59ea42139 349 Pfam PF10282 Lactonase, 7-bladed beta-propeller 9 347 4.9E-84 T 10-11-2016 IPR019405 Lactonase, 7-bladed beta propeller KEGG: 00030+3.1.1.31 A4G23_RS27055 f29b827004e9bcb0a0d5b0a59ea42139 349 Gene3D G3DSA:2.130.10.10 9 348 3.8E-79 T 10-11-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 A4G23_RS27055 f29b827004e9bcb0a0d5b0a59ea42139 349 SUPERFAMILY SSF51004 14 329 1.01E-35 T 10-11-2016 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain A4G23_RS25510 872fb2a50e72bce0d7985c44a8d635fd 628 Gene3D G3DSA:3.30.565.10 485 571 4.5E-7 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS25510 872fb2a50e72bce0d7985c44a8d635fd 628 SUPERFAMILY SSF55874 480 570 3.01E-15 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS25510 872fb2a50e72bce0d7985c44a8d635fd 628 SUPERFAMILY SSF55781 211 385 4.14E-17 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS25510 872fb2a50e72bce0d7985c44a8d635fd 628 SMART SM00065 221 368 0.01 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS25510 872fb2a50e72bce0d7985c44a8d635fd 628 SMART SM00065 53 200 2.0E-18 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS25510 872fb2a50e72bce0d7985c44a8d635fd 628 Gene3D G3DSA:3.30.450.40 200 365 1.5E-17 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS25510 872fb2a50e72bce0d7985c44a8d635fd 628 Gene3D G3DSA:3.30.450.40 33 199 2.1E-30 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS25510 872fb2a50e72bce0d7985c44a8d635fd 628 Pfam PF07730 Histidine kinase 376 436 1.2E-9 T 10-11-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4G23_RS25510 872fb2a50e72bce0d7985c44a8d635fd 628 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 486 544 8.2E-5 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS25510 872fb2a50e72bce0d7985c44a8d635fd 628 SMART SM00387 482 572 2.1E-6 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS25510 872fb2a50e72bce0d7985c44a8d635fd 628 SUPERFAMILY SSF55781 35 218 2.4E-38 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS25510 872fb2a50e72bce0d7985c44a8d635fd 628 Pfam PF13185 GAF domain 222 359 2.5E-11 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS25510 872fb2a50e72bce0d7985c44a8d635fd 628 Pfam PF13185 GAF domain 52 191 5.8E-18 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS13700 4378061ec48438e4d2cbccc115765abb 371 Gene3D G3DSA:1.10.260.40 23 77 1.8E-23 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS13700 4378061ec48438e4d2cbccc115765abb 371 Pfam PF13377 Periplasmic binding protein-like domain 194 353 1.3E-29 T 10-11-2016 A4G23_RS13700 4378061ec48438e4d2cbccc115765abb 371 Pfam PF00356 Bacterial regulatory proteins, lacI family 24 68 7.5E-14 T 10-11-2016 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4G23_RS13700 4378061ec48438e4d2cbccc115765abb 371 ProSitePatterns PS00356 LacI-type HTH domain signature. 24 42 - T 10-11-2016 A4G23_RS13700 4378061ec48438e4d2cbccc115765abb 371 Gene3D G3DSA:3.40.50.2300 192 354 2.9E-34 T 10-11-2016 A4G23_RS13700 4378061ec48438e4d2cbccc115765abb 371 Gene3D G3DSA:3.40.50.2300 78 191 4.0E-10 T 10-11-2016 A4G23_RS13700 4378061ec48438e4d2cbccc115765abb 371 SUPERFAMILY SSF47413 21 79 2.73E-16 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS13700 4378061ec48438e4d2cbccc115765abb 371 SMART SM00354 21 91 2.0E-20 T 10-11-2016 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A4G23_RS13700 4378061ec48438e4d2cbccc115765abb 371 SUPERFAMILY SSF53822 100 357 1.23E-35 T 10-11-2016 IPR028082 Periplasmic binding protein-like I A4G23_RS05305 b2b893aa7fb1fa5390bb02180a3b533c 202 Gene3D G3DSA:3.40.50.300 10 202 3.2E-67 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05305 b2b893aa7fb1fa5390bb02180a3b533c 202 SUPERFAMILY SSF52540 12 202 2.21E-60 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05305 b2b893aa7fb1fa5390bb02180a3b533c 202 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 19 202 5.0E-69 T 10-11-2016 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 A4G23_RS05305 b2b893aa7fb1fa5390bb02180a3b533c 202 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 22 202 6.7E-60 T 10-11-2016 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 A4G23_RS05305 b2b893aa7fb1fa5390bb02180a3b533c 202 PIRSF PIRSF015617 2 202 2.5E-65 T 10-11-2016 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 A4G23_RS10405 778338826c33481241ba1cb03a9a0d2d 322 SUPERFAMILY SSF101386 128 225 1.47E-22 T 10-11-2016 A4G23_RS10405 778338826c33481241ba1cb03a9a0d2d 322 SUPERFAMILY SSF53790 25 95 5.82E-6 T 10-11-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A4G23_RS10405 778338826c33481241ba1cb03a9a0d2d 322 Gene3D G3DSA:1.10.287.1080 128 198 5.2E-12 T 10-11-2016 A4G23_RS10405 778338826c33481241ba1cb03a9a0d2d 322 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 146 221 6.8E-26 T 10-11-2016 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core A4G23_RS13100 951fb4d7066036a0d17eb3ad1893c4c5 151 Pfam PF07179 SseB protein N-terminal domain 38 139 9.6E-8 T 10-11-2016 IPR009839 SseB protein N-terminal domain A4G23_RS22395 8734ba30db4f9120e72a6a69fa870399 1043 Pfam PF04738 Lantibiotic dehydratase, C terminus 722 981 1.4E-28 T 10-11-2016 IPR006827 Lantibiotic dehydratase, C-terminal A4G23_RS22395 8734ba30db4f9120e72a6a69fa870399 1043 Pfam PF04738 Lantibiotic dehydratase, C terminus 269 473 1.3E-10 T 10-11-2016 IPR006827 Lantibiotic dehydratase, C-terminal A4G23_RS22395 8734ba30db4f9120e72a6a69fa870399 1043 Pfam PF04738 Lantibiotic dehydratase, C terminus 170 242 1.9E-8 T 10-11-2016 IPR006827 Lantibiotic dehydratase, C-terminal A4G23_RS24270 b6a6d1f81ee9efc91f507353ae375892 401 PIRSF PIRSF016578 5 396 1.2E-17 T 10-11-2016 A4G23_RS24270 b6a6d1f81ee9efc91f507353ae375892 401 Gene3D G3DSA:2.40.110.10 125 231 2.4E-33 T 10-11-2016 A4G23_RS24270 b6a6d1f81ee9efc91f507353ae375892 401 SUPERFAMILY SSF47203 245 397 2.99E-53 T 10-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4G23_RS24270 b6a6d1f81ee9efc91f507353ae375892 401 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 11 122 1.1E-31 T 10-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 A4G23_RS24270 b6a6d1f81ee9efc91f507353ae375892 401 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 126 230 7.6E-21 T 10-11-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 A4G23_RS24270 b6a6d1f81ee9efc91f507353ae375892 401 Gene3D G3DSA:1.20.140.10 232 398 6.8E-60 T 10-11-2016 A4G23_RS24270 b6a6d1f81ee9efc91f507353ae375892 401 SUPERFAMILY SSF56645 9 253 5.63E-71 T 10-11-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 A4G23_RS24270 b6a6d1f81ee9efc91f507353ae375892 401 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 245 394 1.5E-46 T 10-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4G23_RS24270 b6a6d1f81ee9efc91f507353ae375892 401 Gene3D G3DSA:1.10.540.10 9 123 4.0E-38 T 10-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 A4G23_RS24565 bcd5a2a26749f2a51b7363b88d884276 314 Gene3D G3DSA:3.40.47.10 1 160 3.2E-58 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS24565 bcd5a2a26749f2a51b7363b88d884276 314 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 224 311 2.9E-25 T 10-11-2016 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A4G23_RS24565 bcd5a2a26749f2a51b7363b88d884276 314 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 2 313 58.342 T 10-11-2016 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A4G23_RS24565 bcd5a2a26749f2a51b7363b88d884276 314 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 4 312 1.7E-88 T 10-11-2016 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A4G23_RS24565 bcd5a2a26749f2a51b7363b88d884276 314 Gene3D G3DSA:3.40.47.10 161 311 3.9E-37 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS24565 bcd5a2a26749f2a51b7363b88d884276 314 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 107 180 3.5E-27 T 10-11-2016 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A4G23_RS24565 bcd5a2a26749f2a51b7363b88d884276 314 SUPERFAMILY SSF53901 4 311 2.24E-56 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS23445 5a4848fd21e49d32a1b6d22d35248d57 577 SUPERFAMILY SSF90123 6 298 1.44E-35 T 10-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A4G23_RS23445 5a4848fd21e49d32a1b6d22d35248d57 577 SUPERFAMILY SSF90123 476 484 1.44E-35 T 10-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A4G23_RS23445 5a4848fd21e49d32a1b6d22d35248d57 577 SUPERFAMILY SSF52540 330 568 1.28E-82 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS23445 5a4848fd21e49d32a1b6d22d35248d57 577 Pfam PF00664 ABC transporter transmembrane region 21 275 7.2E-12 T 10-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A4G23_RS23445 5a4848fd21e49d32a1b6d22d35248d57 577 ProSitePatterns PS00211 ABC transporters family signature. 472 486 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS23445 5a4848fd21e49d32a1b6d22d35248d57 577 Gene3D G3DSA:3.40.50.300 332 564 9.9E-77 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS23445 5a4848fd21e49d32a1b6d22d35248d57 577 Pfam PF00005 ABC transporter 351 500 3.4E-33 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS23445 5a4848fd21e49d32a1b6d22d35248d57 577 Gene3D G3DSA:1.20.1560.10 6 319 1.4E-31 T 10-11-2016 A4G23_RS23445 5a4848fd21e49d32a1b6d22d35248d57 577 SMART SM00382 360 546 6.2E-17 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS27265 7c01b2fe20a7cfc359504c094ca23111 215 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 208 4.0E-19 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS27265 7c01b2fe20a7cfc359504c094ca23111 215 Gene3D G3DSA:3.40.50.2300 8 123 1.2E-8 T 10-11-2016 A4G23_RS27265 7c01b2fe20a7cfc359504c094ca23111 215 SMART SM00421 152 209 3.2E-22 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS27265 7c01b2fe20a7cfc359504c094ca23111 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 3.6E-12 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS27265 7c01b2fe20a7cfc359504c094ca23111 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 3.6E-12 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS27265 7c01b2fe20a7cfc359504c094ca23111 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 3.6E-12 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS27265 7c01b2fe20a7cfc359504c094ca23111 215 SUPERFAMILY SSF52172 8 146 3.92E-7 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS27265 7c01b2fe20a7cfc359504c094ca23111 215 ProSitePatterns PS00622 LuxR-type HTH domain signature. 169 196 - T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS27265 7c01b2fe20a7cfc359504c094ca23111 215 SUPERFAMILY SSF46894 146 211 8.5E-20 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS27265 7c01b2fe20a7cfc359504c094ca23111 215 Gene3D G3DSA:1.10.10.10 124 211 2.9E-25 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS00915 a32901738b9e1556bf30a0401591360d 335 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 120 138 1.3E-8 T 10-11-2016 A4G23_RS00915 a32901738b9e1556bf30a0401591360d 335 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 20 39 1.3E-8 T 10-11-2016 A4G23_RS00915 a32901738b9e1556bf30a0401591360d 335 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 270 292 1.3E-8 T 10-11-2016 A4G23_RS00915 a32901738b9e1556bf30a0401591360d 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 280 298 2.2E-16 T 10-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4G23_RS00915 a32901738b9e1556bf30a0401591360d 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 19 41 2.2E-16 T 10-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4G23_RS00915 a32901738b9e1556bf30a0401591360d 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 158 182 2.2E-16 T 10-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4G23_RS00915 a32901738b9e1556bf30a0401591360d 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 121 129 2.2E-16 T 10-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4G23_RS00915 a32901738b9e1556bf30a0401591360d 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 143 155 2.2E-16 T 10-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4G23_RS00915 a32901738b9e1556bf30a0401591360d 335 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 19 304 1.4E-15 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS00915 a32901738b9e1556bf30a0401591360d 335 Gene3D G3DSA:3.50.50.60 18 145 3.0E-20 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS00915 a32901738b9e1556bf30a0401591360d 335 SUPERFAMILY SSF51905 17 323 8.64E-29 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS00915 a32901738b9e1556bf30a0401591360d 335 Gene3D G3DSA:3.50.50.60 146 243 5.9E-36 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS14655 6aef346df5cfe32b461a325984dbe7d6 81 Pfam PF04149 Domain of unknown function (DUF397) 26 77 1.3E-23 T 10-11-2016 IPR007278 Domain of unknown function DUF397 A4G23_RS14655 6aef346df5cfe32b461a325984dbe7d6 81 Pfam PF04149 Domain of unknown function (DUF397) 6 25 1.7E-8 T 10-11-2016 IPR007278 Domain of unknown function DUF397 A4G23_RS18950 3d0440416304d56f9d05682d6f4637a9 326 SUPERFAMILY SSF48452 19 109 4.98E-10 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS18950 3d0440416304d56f9d05682d6f4637a9 326 Gene3D G3DSA:1.25.40.10 21 110 4.0E-10 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS25255 568367c94c229cf69f40c29d4567dd1b 886 Pfam PF13191 AAA ATPase domain 14 184 6.6E-21 T 10-11-2016 A4G23_RS25255 568367c94c229cf69f40c29d4567dd1b 886 Gene3D G3DSA:3.40.50.300 145 210 4.4E-7 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS25255 568367c94c229cf69f40c29d4567dd1b 886 Gene3D G3DSA:3.40.50.300 17 109 4.4E-7 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS25255 568367c94c229cf69f40c29d4567dd1b 886 SMART SM00382 37 216 7.7E-4 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS25255 568367c94c229cf69f40c29d4567dd1b 886 SUPERFAMILY SSF52540 6 87 2.19E-12 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS25255 568367c94c229cf69f40c29d4567dd1b 886 SUPERFAMILY SSF52540 127 237 2.19E-12 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS25255 568367c94c229cf69f40c29d4567dd1b 886 SUPERFAMILY SSF48452 403 444 3.56E-7 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS25255 568367c94c229cf69f40c29d4567dd1b 886 SUPERFAMILY SSF48452 606 674 3.56E-7 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS25255 568367c94c229cf69f40c29d4567dd1b 886 Gene3D G3DSA:1.25.40.10 409 441 6.0E-15 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS25255 568367c94c229cf69f40c29d4567dd1b 886 Gene3D G3DSA:1.25.40.10 477 762 6.0E-15 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS03000 1ec6336b02645e976c19720e585309a2 319 Pfam PF00892 EamA-like transporter family 20 158 7.6E-11 T 10-11-2016 IPR000620 EamA domain GO:0016020|GO:0016021 A4G23_RS03000 1ec6336b02645e976c19720e585309a2 319 Pfam PF00892 EamA-like transporter family 170 306 1.4E-17 T 10-11-2016 IPR000620 EamA domain GO:0016020|GO:0016021 A4G23_RS03000 1ec6336b02645e976c19720e585309a2 319 SUPERFAMILY SSF103481 54 161 1.29E-9 T 10-11-2016 A4G23_RS03000 1ec6336b02645e976c19720e585309a2 319 SUPERFAMILY SSF103481 206 310 1.44E-12 T 10-11-2016 A4G23_RS18560 717aa1ccaef58cdc33ed3692fb5bc58d 235 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 48 205 4.4E-32 T 10-11-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS18560 717aa1ccaef58cdc33ed3692fb5bc58d 235 SUPERFAMILY SSF88946 48 128 6.28E-24 T 10-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS18560 717aa1ccaef58cdc33ed3692fb5bc58d 235 Pfam PF08281 Sigma-70, region 4 150 201 2.7E-16 T 10-11-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS18560 717aa1ccaef58cdc33ed3692fb5bc58d 235 SUPERFAMILY SSF88659 144 206 3.18E-17 T 10-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS18560 717aa1ccaef58cdc33ed3692fb5bc58d 235 Gene3D G3DSA:1.10.10.10 144 207 4.4E-25 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS18560 717aa1ccaef58cdc33ed3692fb5bc58d 235 Pfam PF04542 Sigma-70 region 2 52 117 5.0E-21 T 10-11-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS18560 717aa1ccaef58cdc33ed3692fb5bc58d 235 Gene3D G3DSA:1.10.1740.10 46 118 2.6E-26 T 10-11-2016 A4G23_RS05880 67d66c7b68dd6804c5b38d2573ea99db 289 Pfam PF00005 ABC transporter 30 195 5.4E-28 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS05880 67d66c7b68dd6804c5b38d2573ea99db 289 SMART SM00382 39 245 3.7E-7 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS05880 67d66c7b68dd6804c5b38d2573ea99db 289 Gene3D G3DSA:3.40.50.300 12 267 2.9E-63 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05880 67d66c7b68dd6804c5b38d2573ea99db 289 SUPERFAMILY SSF52540 9 118 1.81E-57 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05880 67d66c7b68dd6804c5b38d2573ea99db 289 SUPERFAMILY SSF52540 147 260 1.81E-57 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05880 67d66c7b68dd6804c5b38d2573ea99db 289 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 245 267 9.3E-12 T 10-11-2016 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal A4G23_RS26940 0d3e264719d1c7f42c8342e64b191e7d 183 Gene3D G3DSA:2.60.120.10 15 174 9.0E-24 T 10-11-2016 IPR014710 RmlC-like jelly roll fold A4G23_RS26940 0d3e264719d1c7f42c8342e64b191e7d 183 SUPERFAMILY SSF51182 39 155 1.48E-21 T 10-11-2016 IPR011051 RmlC-like cupin domain A4G23_RS26940 0d3e264719d1c7f42c8342e64b191e7d 183 Pfam PF00190 Cupin 34 138 3.9E-15 T 10-11-2016 IPR006045 Cupin 1 GO:0045735 A4G23_RS25530 bb2c0e3b88b234e901dce9df5ba89e56 222 Pfam PF14333 Domain of unknown function (DUF4389) 155 205 2.4E-7 T 10-11-2016 IPR025498 Protein of unknown function DUF4389 A4G23_RS25530 bb2c0e3b88b234e901dce9df5ba89e56 222 Pfam PF14333 Domain of unknown function (DUF4389) 27 98 4.6E-13 T 10-11-2016 IPR025498 Protein of unknown function DUF4389 A4G23_RS26375 8a4698f95a7429270678e10c3b16f0dd 314 Gene3D G3DSA:3.30.2010.10 118 183 1.3E-16 T 10-11-2016 A4G23_RS26375 8a4698f95a7429270678e10c3b16f0dd 314 Pfam PF01435 Peptidase family M48 104 187 4.7E-14 T 10-11-2016 IPR001915 Peptidase M48 GO:0004222|GO:0006508 A4G23_RS05790 ba56ff2513f5227dd97bf65d7d6236e4 403 Gene3D G3DSA:3.40.640.10 50 278 5.9E-68 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS05790 ba56ff2513f5227dd97bf65d7d6236e4 403 Pfam PF00155 Aminotransferase class I and II 34 393 2.9E-51 T 10-11-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4G23_RS05790 ba56ff2513f5227dd97bf65d7d6236e4 403 Gene3D G3DSA:3.90.1150.10 279 402 2.3E-39 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS05790 ba56ff2513f5227dd97bf65d7d6236e4 403 SUPERFAMILY SSF53383 4 399 2.02E-96 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS26915 3a8d5c7bd5c155537daf037aa3c70d4d 158 SMART SM00448 5 119 8.5E-20 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS26915 3a8d5c7bd5c155537daf037aa3c70d4d 158 SUPERFAMILY SSF52172 4 126 1.85E-30 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS26915 3a8d5c7bd5c155537daf037aa3c70d4d 158 Gene3D G3DSA:3.40.50.2300 5 128 3.6E-27 T 10-11-2016 A4G23_RS26915 3a8d5c7bd5c155537daf037aa3c70d4d 158 Pfam PF00072 Response regulator receiver domain 7 119 7.6E-20 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS22765 202c9325836282e81b209f52b830295f 223 Gene3D G3DSA:1.20.120.530 83 216 2.9E-27 T 10-11-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal A4G23_RS22765 202c9325836282e81b209f52b830295f 223 Pfam PF07729 FCD domain 91 211 7.9E-24 T 10-11-2016 IPR011711 GntR, C-terminal A4G23_RS22765 202c9325836282e81b209f52b830295f 223 SMART SM00345 21 79 5.6E-13 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS22765 202c9325836282e81b209f52b830295f 223 Pfam PF00392 Bacterial regulatory proteins, gntR family 18 79 1.4E-15 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS22765 202c9325836282e81b209f52b830295f 223 SMART SM00895 89 213 9.3E-14 T 10-11-2016 IPR011711 GntR, C-terminal A4G23_RS22765 202c9325836282e81b209f52b830295f 223 Gene3D G3DSA:1.10.10.10 12 80 1.1E-21 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS22765 202c9325836282e81b209f52b830295f 223 SUPERFAMILY SSF46785 15 83 3.55E-17 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS22765 202c9325836282e81b209f52b830295f 223 SUPERFAMILY SSF48008 86 218 1.99E-26 T 10-11-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal A4G23_RS09570 9bcfe57ab7a72670028054d9b5756d1e 491 Gene3D G3DSA:1.20.1250.20 39 208 3.8E-20 T 10-11-2016 A4G23_RS09570 9bcfe57ab7a72670028054d9b5756d1e 491 Gene3D G3DSA:1.20.1250.20 287 485 1.4E-6 T 10-11-2016 A4G23_RS09570 9bcfe57ab7a72670028054d9b5756d1e 491 Pfam PF07690 Major Facilitator Superfamily 41 426 2.5E-28 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS09570 9bcfe57ab7a72670028054d9b5756d1e 491 SUPERFAMILY SSF103473 267 484 1.11E-33 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS09570 9bcfe57ab7a72670028054d9b5756d1e 491 SUPERFAMILY SSF103473 31 217 1.11E-33 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS06285 e5f284c73249970e98473ba6933adbc7 178 SMART SM00947 37 175 1.2E-24 T 10-11-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A4G23_RS06285 e5f284c73249970e98473ba6933adbc7 178 Gene3D G3DSA:3.40.1050.10 17 175 8.4E-34 T 10-11-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A4G23_RS06285 e5f284c73249970e98473ba6933adbc7 178 SUPERFAMILY SSF53056 14 176 1.01E-34 T 10-11-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A4G23_RS06285 e5f284c73249970e98473ba6933adbc7 178 Pfam PF00484 Carbonic anhydrase 45 142 6.2E-11 T 10-11-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A4G23_RS02045 353a8f105ea76b20f8c42ddd5058cbee 373 Gene3D G3DSA:3.40.640.10 12 247 2.7E-71 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS02045 353a8f105ea76b20f8c42ddd5058cbee 373 PIRSF PIRSF000390 7 371 1.8E-84 T 10-11-2016 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A4G23_RS02045 353a8f105ea76b20f8c42ddd5058cbee 373 SUPERFAMILY SSF53383 7 366 1.22E-86 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS02045 353a8f105ea76b20f8c42ddd5058cbee 373 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 14 364 3.9E-91 T 10-11-2016 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A4G23_RS02045 353a8f105ea76b20f8c42ddd5058cbee 373 Gene3D G3DSA:3.90.1150.10 252 367 1.2E-10 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS11850 4e9c476b74b3f3acf07e51bb6bdfe1de 207 Gene3D G3DSA:3.40.50.1000 69 196 1.0E-23 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS11850 4e9c476b74b3f3acf07e51bb6bdfe1de 207 SUPERFAMILY SSF56784 4 195 5.33E-36 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS11850 4e9c476b74b3f3acf07e51bb6bdfe1de 207 Gene3D G3DSA:1.10.150.240 16 68 4.8E-12 T 10-11-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 A4G23_RS11850 4e9c476b74b3f3acf07e51bb6bdfe1de 207 Pfam PF12710 haloacid dehalogenase-like hydrolase 6 158 7.7E-12 T 10-11-2016 A4G23_RS11085 e50922d73c3cc3e69018c7bbd92353d9 77 Pfam PF00313 'Cold-shock' DNA-binding domain 4 53 7.3E-7 T 10-11-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4G23_RS11085 e50922d73c3cc3e69018c7bbd92353d9 77 SUPERFAMILY SSF50249 2 54 2.43E-7 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS11085 e50922d73c3cc3e69018c7bbd92353d9 77 Gene3D G3DSA:2.40.50.140 4 69 8.0E-11 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS03380 233bf5c8b4926b2a81b3ff5033370251 368 Pfam PF01872 RibD C-terminal domain 150 353 2.0E-49 T 10-11-2016 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 A4G23_RS03380 233bf5c8b4926b2a81b3ff5033370251 368 SUPERFAMILY SSF53597 148 357 2.42E-55 T 10-11-2016 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 A4G23_RS03380 233bf5c8b4926b2a81b3ff5033370251 368 Gene3D G3DSA:3.40.430.10 131 360 3.4E-71 T 10-11-2016 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 A4G23_RS03380 233bf5c8b4926b2a81b3ff5033370251 368 SUPERFAMILY SSF53927 6 144 7.72E-42 T 10-11-2016 IPR016193 Cytidine deaminase-like GO:0003824 A4G23_RS03380 233bf5c8b4926b2a81b3ff5033370251 368 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 54 92 - T 10-11-2016 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 A4G23_RS03380 233bf5c8b4926b2a81b3ff5033370251 368 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 6 103 1.7E-18 T 10-11-2016 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 A4G23_RS03380 233bf5c8b4926b2a81b3ff5033370251 368 PIRSF PIRSF006769 1 361 2.0E-122 T 10-11-2016 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 A4G23_RS03380 233bf5c8b4926b2a81b3ff5033370251 368 Gene3D G3DSA:3.40.140.10 6 130 1.6E-28 T 10-11-2016 A4G23_RS03380 233bf5c8b4926b2a81b3ff5033370251 368 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 149 358 2.6E-54 T 10-11-2016 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 A4G23_RS03380 233bf5c8b4926b2a81b3ff5033370251 368 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 10 354 4.5E-109 T 10-11-2016 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 A4G23_RS17325 4c663c5e0d854651c8d0c7e5238d8ef1 198 SUPERFAMILY SSF55144 5 173 1.83E-29 T 10-11-2016 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase A4G23_RS17325 4c663c5e0d854651c8d0c7e5238d8ef1 198 Pfam PF13563 2'-5' RNA ligase superfamily 14 158 1.0E-20 T 10-11-2016 A4G23_RS17325 4c663c5e0d854651c8d0c7e5238d8ef1 198 Gene3D G3DSA:3.90.1140.10 8 174 4.5E-24 T 10-11-2016 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase A4G23_RS13550 c29152f6a64703fe3849e0bc5ff93d50 481 Pfam PF01966 HD domain 270 364 2.6E-15 T 10-11-2016 IPR006674 HD domain A4G23_RS13550 c29152f6a64703fe3849e0bc5ff93d50 481 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 195 256 2.9E-20 T 10-11-2016 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 A4G23_RS13550 c29152f6a64703fe3849e0bc5ff93d50 481 TIGRFAM TIGR02692 tRNA_CCA_actino: CCA tRNA nucleotidyltransferase 18 477 4.0E-249 T 10-11-2016 IPR014065 tRNA adenylyltransferase A4G23_RS13550 c29152f6a64703fe3849e0bc5ff93d50 481 SUPERFAMILY SSF81301 26 165 8.17E-38 T 10-11-2016 A4G23_RS13550 c29152f6a64703fe3849e0bc5ff93d50 481 Gene3D G3DSA:1.10.3090.10 168 354 6.7E-60 T 10-11-2016 A4G23_RS13550 c29152f6a64703fe3849e0bc5ff93d50 481 Gene3D G3DSA:1.10.3090.10 422 444 6.7E-60 T 10-11-2016 A4G23_RS13550 c29152f6a64703fe3849e0bc5ff93d50 481 SMART SM00471 266 481 1.0E-6 T 10-11-2016 IPR003607 HD/PDEase domain A4G23_RS13550 c29152f6a64703fe3849e0bc5ff93d50 481 Pfam PF01743 Poly A polymerase head domain 46 168 1.8E-32 T 10-11-2016 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 A4G23_RS13550 c29152f6a64703fe3849e0bc5ff93d50 481 SUPERFAMILY SSF81891 166 478 1.57E-71 T 10-11-2016 A4G23_RS13550 c29152f6a64703fe3849e0bc5ff93d50 481 TIGRFAM TIGR00277 HDIG: HDIG domain 267 346 1.3E-17 T 10-11-2016 IPR006675 HDIG domain A4G23_RS13550 c29152f6a64703fe3849e0bc5ff93d50 481 Gene3D G3DSA:3.30.460.10 26 167 1.1E-45 T 10-11-2016 A4G23_RS18960 a4eeb24499370cfa0821ad97aa9344b5 245 SUPERFAMILY SSF47090 35 106 2.28E-19 T 10-11-2016 IPR002477 Peptidoglycan binding-like A4G23_RS18960 a4eeb24499370cfa0821ad97aa9344b5 245 Gene3D G3DSA:1.10.101.10 38 108 4.9E-22 T 10-11-2016 IPR002477 Peptidoglycan binding-like A4G23_RS18960 a4eeb24499370cfa0821ad97aa9344b5 245 SUPERFAMILY SSF55166 116 243 5.89E-27 T 10-11-2016 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 A4G23_RS18960 a4eeb24499370cfa0821ad97aa9344b5 245 Gene3D G3DSA:3.30.1380.10 117 240 3.0E-34 T 10-11-2016 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 A4G23_RS18960 a4eeb24499370cfa0821ad97aa9344b5 245 Pfam PF01471 Putative peptidoglycan binding domain 48 104 1.1E-15 T 10-11-2016 IPR002477 Peptidoglycan binding-like A4G23_RS18960 a4eeb24499370cfa0821ad97aa9344b5 245 Pfam PF08291 Peptidase M15 117 231 9.8E-34 T 10-11-2016 IPR013230 Peptidase M15A, C-terminal MetaCyc: PWY-6470 A4G23_RS17600 dfe79b77df3b86b014e9ade049d1d0e1 134 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 61 101 - T 10-11-2016 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 A4G23_RS17600 dfe79b77df3b86b014e9ade049d1d0e1 134 SUPERFAMILY SSF53927 8 133 4.52E-39 T 10-11-2016 IPR016193 Cytidine deaminase-like GO:0003824 A4G23_RS17600 dfe79b77df3b86b014e9ade049d1d0e1 134 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 14 105 1.1E-10 T 10-11-2016 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 A4G23_RS17600 dfe79b77df3b86b014e9ade049d1d0e1 134 Gene3D G3DSA:3.40.140.10 10 134 1.8E-40 T 10-11-2016 A4G23_RS17760 56562c87f5629e44434a9ca1d1187f9b 173 Pfam PF07883 Cupin domain 54 121 2.0E-16 T 10-11-2016 IPR013096 Cupin 2, conserved barrel A4G23_RS17760 56562c87f5629e44434a9ca1d1187f9b 173 SUPERFAMILY SSF51182 35 156 8.92E-26 T 10-11-2016 IPR011051 RmlC-like cupin domain A4G23_RS17760 56562c87f5629e44434a9ca1d1187f9b 173 Gene3D G3DSA:2.60.120.10 31 168 1.1E-31 T 10-11-2016 IPR014710 RmlC-like jelly roll fold A4G23_RS23995 023847d2fc93bef0a679bca9e00cd394 498 SUPERFAMILY SSF46894 400 467 2.35E-17 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS23995 023847d2fc93bef0a679bca9e00cd394 498 SMART SM00421 412 469 1.8E-16 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS23995 023847d2fc93bef0a679bca9e00cd394 498 SUPERFAMILY SSF52540 24 216 9.72E-9 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS23995 023847d2fc93bef0a679bca9e00cd394 498 Gene3D G3DSA:1.10.10.10 410 467 2.7E-19 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS23995 023847d2fc93bef0a679bca9e00cd394 498 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 415 429 3.8E-10 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS23995 023847d2fc93bef0a679bca9e00cd394 498 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 445 457 3.8E-10 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS23995 023847d2fc93bef0a679bca9e00cd394 498 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 429 445 3.8E-10 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS23995 023847d2fc93bef0a679bca9e00cd394 498 Pfam PF00196 Bacterial regulatory proteins, luxR family 415 467 1.1E-15 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS09255 682f5bda7392502f61e3403afeade7fb 219 TIGRFAM TIGR03004 ectoine_ehuC: ectoine/hydroxyectoine ABC transporter, permease protein EhuC 10 211 9.0E-66 T 10-11-2016 IPR014342 Ectoine/hydroxyectoine ABC transporter, permease protein EhuC A4G23_RS09255 682f5bda7392502f61e3403afeade7fb 219 Gene3D G3DSA:1.10.3720.10 8 210 1.1E-44 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS09255 682f5bda7392502f61e3403afeade7fb 219 SUPERFAMILY SSF161098 8 196 1.83E-40 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS09255 682f5bda7392502f61e3403afeade7fb 219 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 10 105 5.5E-23 T 10-11-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 A4G23_RS09255 682f5bda7392502f61e3403afeade7fb 219 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 31 211 6.9E-22 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS13155 2c9111f3265be3c6fd72a0c8b58ddc49 482 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 252 479 1.7E-76 T 10-11-2016 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A4G23_RS13155 2c9111f3265be3c6fd72a0c8b58ddc49 482 SUPERFAMILY SSF47005 157 200 2.49E-10 T 10-11-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A4G23_RS13155 2c9111f3265be3c6fd72a0c8b58ddc49 482 Gene3D G3DSA:3.30.559.10 241 479 6.3E-82 T 10-11-2016 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 A4G23_RS13155 2c9111f3265be3c6fd72a0c8b58ddc49 482 Gene3D G3DSA:2.40.50.100 1 89 1.5E-26 T 10-11-2016 A4G23_RS13155 2c9111f3265be3c6fd72a0c8b58ddc49 482 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 21 50 - T 10-11-2016 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 A4G23_RS13155 2c9111f3265be3c6fd72a0c8b58ddc49 482 SUPERFAMILY SSF52777 240 479 3.02E-75 T 10-11-2016 A4G23_RS13155 2c9111f3265be3c6fd72a0c8b58ddc49 482 Gene3D G3DSA:4.10.320.10 158 208 2.3E-16 T 10-11-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A4G23_RS13155 2c9111f3265be3c6fd72a0c8b58ddc49 482 SUPERFAMILY SSF51230 1 90 3.66E-26 T 10-11-2016 IPR011053 Single hybrid motif A4G23_RS13155 2c9111f3265be3c6fd72a0c8b58ddc49 482 Pfam PF02817 e3 binding domain 162 196 3.4E-13 T 10-11-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A4G23_RS13155 2c9111f3265be3c6fd72a0c8b58ddc49 482 Pfam PF00364 Biotin-requiring enzyme 1 68 3.7E-21 T 10-11-2016 IPR000089 Biotin/lipoyl attachment A4G23_RS19330 1ba74dfba5c6c8f083ce16814bbf5c6c 362 Pfam PF02687 FtsX-like permease family 246 354 7.0E-12 T 10-11-2016 IPR003838 ABC transporter permease protein domain GO:0016020 A4G23_RS24910 5461308d210b8dcc2fb01cea5961efb4 726 Pfam PF13243 Squalene-hopene cyclase C-terminal domain 401 716 2.6E-137 T 10-11-2016 IPR032696 Squalene cyclase, C-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 A4G23_RS24910 5461308d210b8dcc2fb01cea5961efb4 726 TIGRFAM TIGR01507 hopene_cyclase: squalene-hopene cyclase 99 717 5.4E-236 T 10-11-2016 IPR006400 Squalene hopene cyclase GO:0016866|GO:0019746 KEGG: 00030+4.2.1.12|KEGG: 00909+4.2.1.129+5.4.99.17|MetaCyc: PWY-6098|MetaCyc: PWY-7072 A4G23_RS24910 5461308d210b8dcc2fb01cea5961efb4 726 SUPERFAMILY SSF48239 129 395 2.67E-72 T 10-11-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A4G23_RS24910 5461308d210b8dcc2fb01cea5961efb4 726 TIGRFAM TIGR01787 squalene_cyclas: squalene/oxidosqualene cyclases 104 715 8.5E-179 T 10-11-2016 IPR018333 Squalene cyclase GO:0016866 Reactome: R-HSA-191273|Reactome: R-HSA-2426168 A4G23_RS24910 5461308d210b8dcc2fb01cea5961efb4 726 Gene3D G3DSA:1.50.10.20 127 385 8.5E-65 T 10-11-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A4G23_RS24910 5461308d210b8dcc2fb01cea5961efb4 726 Pfam PF13249 Squalene-hopene cyclase N-terminal domain 106 391 2.8E-120 T 10-11-2016 IPR032697 Squalene cyclase, N-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 A4G23_RS24910 5461308d210b8dcc2fb01cea5961efb4 726 Gene3D G3DSA:1.50.10.20 386 716 9.9E-116 T 10-11-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A4G23_RS24910 5461308d210b8dcc2fb01cea5961efb4 726 SUPERFAMILY SSF48239 387 717 2.43E-104 T 10-11-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A4G23_RS24210 aaff18636a47dae568bab73ee3bb1c56 211 SUPERFAMILY SSF48498 105 206 9.58E-7 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS24210 aaff18636a47dae568bab73ee3bb1c56 211 Gene3D G3DSA:1.10.357.10 15 203 4.8E-30 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS24210 aaff18636a47dae568bab73ee3bb1c56 211 SUPERFAMILY SSF46689 24 93 1.54E-16 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS24210 aaff18636a47dae568bab73ee3bb1c56 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 34 80 9.4E-13 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS24210 aaff18636a47dae568bab73ee3bb1c56 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 47 2.9E-5 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS24210 aaff18636a47dae568bab73ee3bb1c56 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 55 78 2.9E-5 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS09360 de3c63da888689b4128a85e6b4867ec4 271 Pfam PF06182 ABC-2 family transporter protein 39 270 4.1E-57 T 10-11-2016 IPR010390 Protein of unknown function DUF990 A4G23_RS20555 73d6967ed26c025bb1442696835113e4 120 Pfam PF02021 Uncharacterised protein family UPF0102 11 103 2.3E-25 T 10-11-2016 IPR003509 Uncharacterised protein family UPF0102 A4G23_RS20555 73d6967ed26c025bb1442696835113e4 120 Hamap MF_00048 UPF0102 protein YraN [yraN]. 4 116 20.119 T 10-11-2016 IPR003509 Uncharacterised protein family UPF0102 A4G23_RS20555 73d6967ed26c025bb1442696835113e4 120 SUPERFAMILY SSF52980 7 105 1.18E-17 T 10-11-2016 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A4G23_RS20555 73d6967ed26c025bb1442696835113e4 120 Gene3D G3DSA:3.40.1350.10 10 119 4.4E-33 T 10-11-2016 IPR011856 tRNA endonuclease-like domain GO:0003676|GO:0004518 Reactome: R-HSA-6784531 A4G23_RS00335 d28c8add5d167b67774d0b6dd6df5973 169 Pfam PF12802 MarR family 43 99 2.1E-11 T 10-11-2016 A4G23_RS00335 d28c8add5d167b67774d0b6dd6df5973 169 SUPERFAMILY SSF46785 25 151 1.37E-23 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS00335 d28c8add5d167b67774d0b6dd6df5973 169 ProSitePatterns PS01117 MarR-type HTH domain signature. 75 109 - T 10-11-2016 IPR023187 Transcriptional regulator MarR-type, conserved site A4G23_RS00335 d28c8add5d167b67774d0b6dd6df5973 169 Gene3D G3DSA:1.10.10.10 26 152 2.6E-26 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS00335 d28c8add5d167b67774d0b6dd6df5973 169 SMART SM00347 36 136 1.9E-16 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS27270 53f7656ccb847df5df47b8ff13e9e472 69 Gene3D G3DSA:3.90.820.10 10 62 6.0E-25 T 10-11-2016 A4G23_RS27270 53f7656ccb847df5df47b8ff13e9e472 69 SUPERFAMILY SSF160582 1 62 4.45E-27 T 10-11-2016 A4G23_RS27270 53f7656ccb847df5df47b8ff13e9e472 69 SMART SM00923 3 53 3.1E-28 T 10-11-2016 IPR005153 MbtH-like protein A4G23_RS27270 53f7656ccb847df5df47b8ff13e9e472 69 Pfam PF03621 MbtH-like protein 1 53 2.4E-25 T 10-11-2016 IPR005153 MbtH-like protein A4G23_RS17025 1ccdcecdceb62118abb7439516526015 465 SUPERFAMILY SSF56176 13 206 4.49E-58 T 10-11-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 A4G23_RS17025 1ccdcecdceb62118abb7439516526015 465 Pfam PF01565 FAD binding domain 40 174 2.1E-33 T 10-11-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 A4G23_RS17025 1ccdcecdceb62118abb7439516526015 465 Gene3D G3DSA:3.30.465.10 97 206 4.2E-18 T 10-11-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 A4G23_RS17025 1ccdcecdceb62118abb7439516526015 465 Pfam PF08031 Berberine and berberine like 413 457 1.4E-9 T 10-11-2016 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 A4G23_RS17025 1ccdcecdceb62118abb7439516526015 465 Gene3D G3DSA:3.30.43.10 26 96 1.9E-13 T 10-11-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 A4G23_RS19960 c3b9ec205c8b03b115ce39e0231ed0b6 217 Pfam PF13671 AAA domain 52 168 7.8E-12 T 10-11-2016 A4G23_RS19960 c3b9ec205c8b03b115ce39e0231ed0b6 217 Gene3D G3DSA:3.40.50.300 51 171 2.6E-9 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS19960 c3b9ec205c8b03b115ce39e0231ed0b6 217 SUPERFAMILY SSF52540 45 168 6.75E-13 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS17440 0e788b6270ba813a689609178a239070 245 Gene3D G3DSA:3.40.50.720 9 232 2.4E-46 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS17440 0e788b6270ba813a689609178a239070 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 3.8E-8 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS17440 0e788b6270ba813a689609178a239070 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 3.8E-8 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS17440 0e788b6270ba813a689609178a239070 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.8E-8 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS17440 0e788b6270ba813a689609178a239070 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 3.8E-8 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS17440 0e788b6270ba813a689609178a239070 245 Pfam PF00106 short chain dehydrogenase 10 201 6.7E-35 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS17440 0e788b6270ba813a689609178a239070 245 SUPERFAMILY SSF51735 2 232 3.8E-48 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS26350 50dac2f0cb28d9e312c1f413016a64f9 338 SUPERFAMILY SSF48613 138 303 1.51E-6 T 10-11-2016 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 A4G23_RS26350 50dac2f0cb28d9e312c1f413016a64f9 338 SMART SM01236 172 277 1.4E-31 T 10-11-2016 A4G23_RS26350 50dac2f0cb28d9e312c1f413016a64f9 338 Gene3D G3DSA:1.20.910.10 107 331 1.5E-56 T 10-11-2016 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 A4G23_RS26350 50dac2f0cb28d9e312c1f413016a64f9 338 Pfam PF14518 Iron-containing redox enzyme 140 315 1.8E-43 T 10-11-2016 IPR028201 PqqC-like protein A4G23_RS10545 d862f6ad5acb53afd0246188b7dcae7e 481 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 6 459 40.22 T 10-11-2016 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 A4G23_RS10545 d862f6ad5acb53afd0246188b7dcae7e 481 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 8 461 2.5E-167 T 10-11-2016 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 A4G23_RS10545 d862f6ad5acb53afd0246188b7dcae7e 481 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 401 436 3.8E-6 T 10-11-2016 IPR001451 Hexapeptide repeat A4G23_RS10545 d862f6ad5acb53afd0246188b7dcae7e 481 Gene3D G3DSA:3.90.550.10 6 252 1.6E-74 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS10545 d862f6ad5acb53afd0246188b7dcae7e 481 Gene3D G3DSA:2.160.10.10 253 330 3.5E-12 T 10-11-2016 A4G23_RS10545 d862f6ad5acb53afd0246188b7dcae7e 481 Pfam PF12804 MobA-like NTP transferase domain 9 139 8.0E-20 T 10-11-2016 IPR025877 MobA-like NTP transferase A4G23_RS10545 d862f6ad5acb53afd0246188b7dcae7e 481 SUPERFAMILY SSF51161 256 467 9.82E-41 T 10-11-2016 IPR011004 Trimeric LpxA-like A4G23_RS10545 d862f6ad5acb53afd0246188b7dcae7e 481 Gene3D G3DSA:2.160.10.10 331 458 1.5E-30 T 10-11-2016 A4G23_RS10545 d862f6ad5acb53afd0246188b7dcae7e 481 SUPERFAMILY SSF53448 8 260 2.29E-62 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS10750 33439cf6cb2409ba92571c294b0ab9d6 208 SUPERFAMILY SSF46955 2 70 1.1E-17 T 10-11-2016 IPR009061 Putative DNA-binding domain A4G23_RS10750 33439cf6cb2409ba92571c294b0ab9d6 208 Gene3D G3DSA:1.10.1660.10 2 71 1.8E-19 T 10-11-2016 A4G23_RS10750 33439cf6cb2409ba92571c294b0ab9d6 208 SMART SM00422 3 67 1.3E-12 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS10750 33439cf6cb2409ba92571c294b0ab9d6 208 Pfam PF13411 MerR HTH family regulatory protein 1 64 2.5E-19 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS00140 66a7596bdb0d07cc8016d0bbefcca99e 377 SUPERFAMILY SSF48264 39 346 3.14E-28 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS00140 66a7596bdb0d07cc8016d0bbefcca99e 377 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 315 324 - T 10-11-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A4G23_RS00140 66a7596bdb0d07cc8016d0bbefcca99e 377 Pfam PF00067 Cytochrome P450 251 337 6.8E-6 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS00140 66a7596bdb0d07cc8016d0bbefcca99e 377 Gene3D G3DSA:1.10.630.10 39 213 2.4E-10 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS00140 66a7596bdb0d07cc8016d0bbefcca99e 377 Gene3D G3DSA:1.10.630.10 214 368 9.1E-20 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS00140 66a7596bdb0d07cc8016d0bbefcca99e 377 PRINTS PR00359 B-class P450 signature 249 260 1.0E-10 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS00140 66a7596bdb0d07cc8016d0bbefcca99e 377 PRINTS PR00359 B-class P450 signature 266 293 1.0E-10 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS00140 66a7596bdb0d07cc8016d0bbefcca99e 377 PRINTS PR00359 B-class P450 signature 322 333 1.0E-10 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS00140 66a7596bdb0d07cc8016d0bbefcca99e 377 PRINTS PR00359 B-class P450 signature 313 322 1.0E-10 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS03210 73efb65f595d0aec245d0f07821d3e5a 205 SMART SM00796 1 192 8.5E-77 T 10-11-2016 IPR003833 Carboxyltransferase domain, subdomain C and D A4G23_RS03210 73efb65f595d0aec245d0f07821d3e5a 205 SUPERFAMILY SSF50891 81 202 4.17E-38 T 10-11-2016 IPR029000 Cyclophilin-like domain A4G23_RS03210 73efb65f595d0aec245d0f07821d3e5a 205 Pfam PF02682 Allophanate hydrolase subunit 1 1 192 6.7E-61 T 10-11-2016 IPR003833 Carboxyltransferase domain, subdomain C and D A4G23_RS03210 73efb65f595d0aec245d0f07821d3e5a 205 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 38 200 9.8E-44 T 10-11-2016 IPR010016 KipI family A4G23_RS03210 73efb65f595d0aec245d0f07821d3e5a 205 Gene3D G3DSA:2.40.100.10 81 202 2.5E-46 T 10-11-2016 IPR029000 Cyclophilin-like domain A4G23_RS15225 2dec792b8c77ac25041b5655aaf852e2 213 Gene3D G3DSA:1.10.10.10 4 91 1.2E-17 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS15225 2dec792b8c77ac25041b5655aaf852e2 213 Pfam PF03551 Transcriptional regulator PadR-like family 8 83 1.8E-11 T 10-11-2016 IPR005149 Transcription regulator PadR, N-terminal A4G23_RS15225 2dec792b8c77ac25041b5655aaf852e2 213 SUPERFAMILY SSF46785 4 178 5.45E-23 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS16305 2e2b4e806371fde4b3a313d603a343ab 351 Gene3D G3DSA:3.30.43.10 8 72 1.0E-23 T 10-11-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 A4G23_RS16305 2e2b4e806371fde4b3a313d603a343ab 351 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 351 78.476 T 10-11-2016 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4G23_RS16305 2e2b4e806371fde4b3a313d603a343ab 351 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 9 343 1.8E-46 T 10-11-2016 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4G23_RS16305 2e2b4e806371fde4b3a313d603a343ab 351 Pfam PF01565 FAD binding domain 22 139 2.8E-21 T 10-11-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 A4G23_RS16305 2e2b4e806371fde4b3a313d603a343ab 351 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 213 347 5.3E-38 T 10-11-2016 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4G23_RS16305 2e2b4e806371fde4b3a313d603a343ab 351 SUPERFAMILY SSF56194 210 349 5.49E-34 T 10-11-2016 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4G23_RS16305 2e2b4e806371fde4b3a313d603a343ab 351 Gene3D G3DSA:3.30.465.10 223 238 1.3E-47 T 10-11-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 A4G23_RS16305 2e2b4e806371fde4b3a313d603a343ab 351 Gene3D G3DSA:3.30.465.10 76 188 1.3E-47 T 10-11-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 A4G23_RS16305 2e2b4e806371fde4b3a313d603a343ab 351 SUPERFAMILY SSF56176 8 183 2.94E-36 T 10-11-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 A4G23_RS16305 2e2b4e806371fde4b3a313d603a343ab 351 Gene3D G3DSA:3.90.78.10 239 350 3.1E-44 T 10-11-2016 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4G23_RS06330 0987c5d111c3518f943fd0a2577f2018 503 SUPERFAMILY SSF51905 2 303 3.74E-47 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS06330 0987c5d111c3518f943fd0a2577f2018 503 SUPERFAMILY SSF51905 459 494 3.74E-47 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS06330 0987c5d111c3518f943fd0a2577f2018 503 Gene3D G3DSA:3.50.50.60 2 54 5.7E-32 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS06330 0987c5d111c3518f943fd0a2577f2018 503 Gene3D G3DSA:3.50.50.60 464 494 5.7E-32 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS06330 0987c5d111c3518f943fd0a2577f2018 503 Gene3D G3DSA:3.50.50.60 87 88 5.7E-32 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS06330 0987c5d111c3518f943fd0a2577f2018 503 Gene3D G3DSA:3.50.50.60 212 308 5.7E-32 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS06330 0987c5d111c3518f943fd0a2577f2018 503 Gene3D G3DSA:3.50.50.60 123 132 5.7E-32 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS06330 0987c5d111c3518f943fd0a2577f2018 503 Pfam PF01593 Flavin containing amine oxidoreductase 14 289 1.6E-18 T 10-11-2016 IPR002937 Amine oxidase GO:0016491|GO:0055114 A4G23_RS00940 cd2ffd16bf99b3c00d4ebf105633dc8c 469 Pfam PF01494 FAD binding domain 17 355 1.1E-9 T 10-11-2016 IPR002938 FAD-binding domain GO:0071949 A4G23_RS00940 cd2ffd16bf99b3c00d4ebf105633dc8c 469 SUPERFAMILY SSF51905 15 207 2.35E-23 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS00940 cd2ffd16bf99b3c00d4ebf105633dc8c 469 SUPERFAMILY SSF51905 315 365 2.35E-23 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS00940 cd2ffd16bf99b3c00d4ebf105633dc8c 469 Gene3D G3DSA:3.50.50.60 317 356 1.0E-17 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS00940 cd2ffd16bf99b3c00d4ebf105633dc8c 469 Gene3D G3DSA:3.50.50.60 17 204 1.0E-17 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS14015 662f42ee61f08808319a1d27928628f0 483 Gene3D G3DSA:3.40.1010.10 231 344 2.2E-26 T 10-11-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A4G23_RS14015 662f42ee61f08808319a1d27928628f0 483 Gene3D G3DSA:3.30.950.10 345 455 2.1E-12 T 10-11-2016 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A4G23_RS14015 662f42ee61f08808319a1d27928628f0 483 TIGRFAM TIGR01467 cobI_cbiL: precorrin-2 C(20)-methyltransferase 2 217 3.5E-53 T 10-11-2016 IPR006364 Precorrin-2 C(20)-methyltransferase domain GO:0008757|GO:0009236 A4G23_RS14015 662f42ee61f08808319a1d27928628f0 483 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 233 439 4.7E-34 T 10-11-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A4G23_RS14015 662f42ee61f08808319a1d27928628f0 483 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 1 200 1.1E-39 T 10-11-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A4G23_RS14015 662f42ee61f08808319a1d27928628f0 483 SUPERFAMILY SSF53790 1 222 4.19E-38 T 10-11-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A4G23_RS14015 662f42ee61f08808319a1d27928628f0 483 TIGRFAM TIGR01466 cobJ_cbiH: precorrin-3B C17-methyltransferase 233 475 1.4E-80 T 10-11-2016 IPR006363 Precorrin-3B C17-methyltransferase domain GO:0008168|GO:0009236 A4G23_RS14015 662f42ee61f08808319a1d27928628f0 483 SUPERFAMILY SSF53790 229 461 1.31E-51 T 10-11-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A4G23_RS14015 662f42ee61f08808319a1d27928628f0 483 Gene3D G3DSA:3.40.1010.10 1 117 1.7E-24 T 10-11-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A4G23_RS20620 46783bda74f3cc3c56850d1c0ebb1022 540 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 72 250 1.1E-14 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS20620 46783bda74f3cc3c56850d1c0ebb1022 540 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 352 526 1.7E-8 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS20620 46783bda74f3cc3c56850d1c0ebb1022 540 SUPERFAMILY SSF161098 277 536 1.31E-45 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS20620 46783bda74f3cc3c56850d1c0ebb1022 540 SUPERFAMILY SSF161098 4 258 1.7E-51 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS20620 46783bda74f3cc3c56850d1c0ebb1022 540 Gene3D G3DSA:1.10.3720.10 282 536 6.7E-45 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS20620 46783bda74f3cc3c56850d1c0ebb1022 540 Gene3D G3DSA:1.10.3720.10 7 259 8.6E-47 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS25230 70c4873b361c6b24a5137f21c8e31dac 739 PIRSF PIRSF009407 1 739 0.0 T 10-11-2016 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 A4G23_RS25230 70c4873b361c6b24a5137f21c8e31dac 739 Pfam PF03971 Monomeric isocitrate dehydrogenase 5 735 0.0 T 10-11-2016 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 A4G23_RS25230 70c4873b361c6b24a5137f21c8e31dac 739 SUPERFAMILY SSF53659 4 738 0.0 T 10-11-2016 A4G23_RS25230 70c4873b361c6b24a5137f21c8e31dac 739 Gene3D G3DSA:3.40.718.10 337 360 1.1E-32 T 10-11-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A4G23_RS25230 70c4873b361c6b24a5137f21c8e31dac 739 Gene3D G3DSA:3.40.718.10 536 643 1.1E-32 T 10-11-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A4G23_RS25230 70c4873b361c6b24a5137f21c8e31dac 739 Gene3D G3DSA:3.40.718.10 146 284 1.1E-32 T 10-11-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A4G23_RS25230 70c4873b361c6b24a5137f21c8e31dac 739 TIGRFAM TIGR00178 monomer_idh: isocitrate dehydrogenase, NADP-dependent 3 738 0.0 T 10-11-2016 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 A4G23_RS16535 4694374b39ac536cc0f209e5a7e4494d 380 Pfam PF01494 FAD binding domain 6 344 1.9E-21 T 10-11-2016 IPR002938 FAD-binding domain GO:0071949 A4G23_RS16535 4694374b39ac536cc0f209e5a7e4494d 380 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 151 166 2.8E-15 T 10-11-2016 A4G23_RS16535 4694374b39ac536cc0f209e5a7e4494d 380 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 300 316 2.8E-15 T 10-11-2016 A4G23_RS16535 4694374b39ac536cc0f209e5a7e4494d 380 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 285 300 2.8E-15 T 10-11-2016 A4G23_RS16535 4694374b39ac536cc0f209e5a7e4494d 380 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 2.8E-15 T 10-11-2016 A4G23_RS16535 4694374b39ac536cc0f209e5a7e4494d 380 SUPERFAMILY SSF51905 7 172 2.47E-51 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS16535 4694374b39ac536cc0f209e5a7e4494d 380 SUPERFAMILY SSF51905 272 350 2.47E-51 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS16535 4694374b39ac536cc0f209e5a7e4494d 380 Gene3D G3DSA:3.50.50.60 6 178 3.3E-32 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS16535 4694374b39ac536cc0f209e5a7e4494d 380 Gene3D G3DSA:3.50.50.60 273 349 3.3E-32 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS26835 05b77824cc0a0b0173fa039fb9054c2c 281 Gene3D G3DSA:3.40.50.720 135 257 2.1E-44 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS26835 05b77824cc0a0b0173fa039fb9054c2c 281 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 1 116 8.3E-37 T 10-11-2016 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A4G23_RS26835 05b77824cc0a0b0173fa039fb9054c2c 281 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 29 51 5.9E-48 T 10-11-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A4G23_RS26835 05b77824cc0a0b0173fa039fb9054c2c 281 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 70 97 5.9E-48 T 10-11-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A4G23_RS26835 05b77824cc0a0b0173fa039fb9054c2c 281 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 150 170 5.9E-48 T 10-11-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A4G23_RS26835 05b77824cc0a0b0173fa039fb9054c2c 281 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 232 248 5.9E-48 T 10-11-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A4G23_RS26835 05b77824cc0a0b0173fa039fb9054c2c 281 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 249 267 5.9E-48 T 10-11-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A4G23_RS26835 05b77824cc0a0b0173fa039fb9054c2c 281 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 105 126 5.9E-48 T 10-11-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A4G23_RS26835 05b77824cc0a0b0173fa039fb9054c2c 281 SUPERFAMILY SSF53223 1 117 1.06E-33 T 10-11-2016 A4G23_RS26835 05b77824cc0a0b0173fa039fb9054c2c 281 SUPERFAMILY SSF51735 129 275 1.6E-42 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS26835 05b77824cc0a0b0173fa039fb9054c2c 281 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 124 275 2.3E-57 T 10-11-2016 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A4G23_RS26835 05b77824cc0a0b0173fa039fb9054c2c 281 Hamap MF_01576 Bifunctional protein FolD [folD]. 1 276 32.85 T 10-11-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A4G23_RS26835 05b77824cc0a0b0173fa039fb9054c2c 281 Gene3D G3DSA:3.40.192.10 2 134 1.1E-39 T 10-11-2016 A4G23_RS26835 05b77824cc0a0b0173fa039fb9054c2c 281 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 253 261 - T 10-11-2016 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A4G23_RS13650 069cc63e3ec684b61bf6686968b3b883 380 Gene3D G3DSA:3.90.1150.10 252 375 3.7E-30 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS13650 069cc63e3ec684b61bf6686968b3b883 380 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 39 373 2.7E-78 T 10-11-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A4G23_RS13650 069cc63e3ec684b61bf6686968b3b883 380 Gene3D G3DSA:3.40.640.10 10 251 2.2E-59 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS13650 069cc63e3ec684b61bf6686968b3b883 380 SUPERFAMILY SSF53383 40 374 1.75E-77 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS13650 069cc63e3ec684b61bf6686968b3b883 380 PIRSF PIRSF001434 4 377 4.7E-103 T 10-11-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A4G23_RS26810 e44f579ba11c495b48474fce967eca19 216 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 58 1.8E-12 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS26810 e44f579ba11c495b48474fce967eca19 216 SUPERFAMILY SSF48498 77 203 2.02E-22 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS26810 e44f579ba11c495b48474fce967eca19 216 Gene3D G3DSA:1.10.357.10 4 185 2.3E-27 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS26810 e44f579ba11c495b48474fce967eca19 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 1.1E-8 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS26810 e44f579ba11c495b48474fce967eca19 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 1.1E-8 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS26810 e44f579ba11c495b48474fce967eca19 216 ProSitePatterns PS01081 TetR-type HTH domain signature. 26 56 - T 10-11-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A4G23_RS26810 e44f579ba11c495b48474fce967eca19 216 SUPERFAMILY SSF46689 4 66 8.21E-15 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS24390 4a834e6d882ec9cc43ed7724634313f0 124 SUPERFAMILY SSF54593 8 109 2.48E-14 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS24390 4a834e6d882ec9cc43ed7724634313f0 124 Gene3D G3DSA:3.10.180.10 3 109 5.4E-17 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS01675 ddcb4e471ed8ceaa327a62a5064e8f0e 157 Gene3D G3DSA:3.90.79.10 3 144 1.6E-24 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS01675 ddcb4e471ed8ceaa327a62a5064e8f0e 157 ProSitePatterns PS00893 Nudix box signature. 41 62 - T 10-11-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A4G23_RS01675 ddcb4e471ed8ceaa327a62a5064e8f0e 157 PRINTS PR00502 NUDIX hydrolase family signature 50 65 2.3E-7 T 10-11-2016 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A4G23_RS01675 ddcb4e471ed8ceaa327a62a5064e8f0e 157 PRINTS PR00502 NUDIX hydrolase family signature 36 50 2.3E-7 T 10-11-2016 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A4G23_RS01675 ddcb4e471ed8ceaa327a62a5064e8f0e 157 Pfam PF00293 NUDIX domain 6 128 2.4E-18 T 10-11-2016 IPR000086 NUDIX hydrolase domain GO:0016787 A4G23_RS01675 ddcb4e471ed8ceaa327a62a5064e8f0e 157 SUPERFAMILY SSF55811 4 131 2.71E-24 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS09450 9ccfa9f25f1abdb3d7583a04bdf3bf7c 316 Gene3D G3DSA:3.40.50.1100 42 143 2.2E-38 T 10-11-2016 A4G23_RS09450 9ccfa9f25f1abdb3d7583a04bdf3bf7c 316 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 32 50 - T 10-11-2016 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 A4G23_RS09450 9ccfa9f25f1abdb3d7583a04bdf3bf7c 316 Gene3D G3DSA:3.40.50.1100 1 41 4.7E-68 T 10-11-2016 A4G23_RS09450 9ccfa9f25f1abdb3d7583a04bdf3bf7c 316 Gene3D G3DSA:3.40.50.1100 149 299 4.7E-68 T 10-11-2016 A4G23_RS09450 9ccfa9f25f1abdb3d7583a04bdf3bf7c 316 TIGRFAM TIGR01136 cysKM: cysteine synthase 9 298 2.4E-111 T 10-11-2016 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 A4G23_RS09450 9ccfa9f25f1abdb3d7583a04bdf3bf7c 316 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 286 9.0E-69 T 10-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4G23_RS09450 9ccfa9f25f1abdb3d7583a04bdf3bf7c 316 SUPERFAMILY SSF53686 5 295 2.75E-88 T 10-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4G23_RS15280 220c15f2aa7b4d461aab6dbbecb2e986 161 Pfam PF11377 Protein of unknown function (DUF3180) 9 149 1.0E-35 T 10-11-2016 IPR021517 Protein of unknown function DUF3180 A4G23_RS18795 d503a5f3c0f3e833f7083d1586040bb4 449 SUPERFAMILY SSF56112 95 158 8.64E-23 T 10-11-2016 IPR011009 Protein kinase-like domain A4G23_RS18795 d503a5f3c0f3e833f7083d1586040bb4 449 SUPERFAMILY SSF56112 195 308 8.64E-23 T 10-11-2016 IPR011009 Protein kinase-like domain A4G23_RS18795 d503a5f3c0f3e833f7083d1586040bb4 449 Gene3D G3DSA:3.90.1200.10 276 308 0.001 T 10-11-2016 A4G23_RS18795 d503a5f3c0f3e833f7083d1586040bb4 449 Pfam PF03109 ABC1 family 113 227 1.1E-30 T 10-11-2016 IPR004147 UbiB domain A4G23_RS04115 aa8ffd6a2a66c4ee3d7f8879bfcc7fc7 128 Gene3D G3DSA:1.10.1900.20 56 117 1.2E-31 T 10-11-2016 A4G23_RS04115 aa8ffd6a2a66c4ee3d7f8879bfcc7fc7 128 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 2 113 2.7E-44 T 10-11-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS04115 aa8ffd6a2a66c4ee3d7f8879bfcc7fc7 128 PRINTS PR00062 Ribosomal protein L20 signature 12 41 3.9E-38 T 10-11-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS04115 aa8ffd6a2a66c4ee3d7f8879bfcc7fc7 128 PRINTS PR00062 Ribosomal protein L20 signature 75 101 3.9E-38 T 10-11-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS04115 aa8ffd6a2a66c4ee3d7f8879bfcc7fc7 128 PRINTS PR00062 Ribosomal protein L20 signature 42 71 3.9E-38 T 10-11-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS04115 aa8ffd6a2a66c4ee3d7f8879bfcc7fc7 128 SUPERFAMILY SSF74731 3 117 3.4E-45 T 10-11-2016 A4G23_RS04115 aa8ffd6a2a66c4ee3d7f8879bfcc7fc7 128 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 27.842 T 10-11-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS04115 aa8ffd6a2a66c4ee3d7f8879bfcc7fc7 128 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 10-11-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS04115 aa8ffd6a2a66c4ee3d7f8879bfcc7fc7 128 Pfam PF00453 Ribosomal protein L20 3 109 3.1E-44 T 10-11-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS04115 aa8ffd6a2a66c4ee3d7f8879bfcc7fc7 128 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 21 72 2.0E-23 T 10-11-2016 A4G23_RS03120 84757e61c7fb15c02a370670670150bb 556 Gene3D G3DSA:3.20.20.60 250 550 6.7E-90 T 10-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A4G23_RS03120 84757e61c7fb15c02a370670670150bb 556 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 252 524 4.6E-80 T 10-11-2016 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 A4G23_RS03120 84757e61c7fb15c02a370670670150bb 556 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 285 304 4.3E-18 T 10-11-2016 A4G23_RS03120 84757e61c7fb15c02a370670670150bb 556 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 484 496 4.3E-18 T 10-11-2016 A4G23_RS03120 84757e61c7fb15c02a370670670150bb 556 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 431 446 4.3E-18 T 10-11-2016 A4G23_RS03120 84757e61c7fb15c02a370670670150bb 556 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 448 463 4.3E-18 T 10-11-2016 A4G23_RS03120 84757e61c7fb15c02a370670670150bb 556 Pfam PF05524 PEP-utilising enzyme, N-terminal 6 123 1.5E-21 T 10-11-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 A4G23_RS03120 84757e61c7fb15c02a370670670150bb 556 Gene3D G3DSA:1.10.274.10 28 129 6.0E-21 T 10-11-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 A4G23_RS03120 84757e61c7fb15c02a370670670150bb 556 PIRSF PIRSF000732 1 556 1.2E-171 T 10-11-2016 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 A4G23_RS03120 84757e61c7fb15c02a370670670150bb 556 Pfam PF00391 PEP-utilising enzyme, mobile domain 150 221 2.0E-22 T 10-11-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A4G23_RS03120 84757e61c7fb15c02a370670670150bb 556 SUPERFAMILY SSF47831 29 140 1.15E-20 T 10-11-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 A4G23_RS03120 84757e61c7fb15c02a370670670150bb 556 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 5 545 2.9E-127 T 10-11-2016 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 A4G23_RS03120 84757e61c7fb15c02a370670670150bb 556 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 181 192 - T 10-11-2016 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 A4G23_RS03120 84757e61c7fb15c02a370670670150bb 556 Gene3D G3DSA:3.50.30.10 130 244 1.4E-34 T 10-11-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A4G23_RS03120 84757e61c7fb15c02a370670670150bb 556 SUPERFAMILY SSF52009 123 240 6.41E-31 T 10-11-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A4G23_RS03120 84757e61c7fb15c02a370670670150bb 556 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 431 449 - T 10-11-2016 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 A4G23_RS03120 84757e61c7fb15c02a370670670150bb 556 SUPERFAMILY SSF51621 246 533 6.54E-87 T 10-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A4G23_RS14940 fdee233e8f5d5539a4467848ec55a838 117 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 16 111 5.5E-32 T 10-11-2016 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 A4G23_RS14940 fdee233e8f5d5539a4467848ec55a838 117 Gene3D G3DSA:3.30.750.24 15 115 3.0E-39 T 10-11-2016 IPR002645 STAS domain A4G23_RS14940 fdee233e8f5d5539a4467848ec55a838 117 Pfam PF01740 STAS domain 14 112 4.0E-18 T 10-11-2016 IPR002645 STAS domain A4G23_RS14940 fdee233e8f5d5539a4467848ec55a838 117 SUPERFAMILY SSF52091 15 114 6.28E-30 T 10-11-2016 IPR002645 STAS domain A4G23_RS24200 83e04b1ae668bdfdf1a3a330a8eca782 489 Pfam PF02589 Uncharacterised ACR, YkgG family COG1556 73 299 8.4E-47 T 10-11-2016 IPR003741 LUD domain A4G23_RS24200 83e04b1ae668bdfdf1a3a330a8eca782 489 Pfam PF11870 Domain of unknown function (DUF3390) 393 484 2.3E-15 T 10-11-2016 IPR024569 4Fe-4S binding protein, C-terminal A4G23_RS24200 83e04b1ae668bdfdf1a3a330a8eca782 489 SUPERFAMILY SSF54862 296 397 3.77E-14 T 10-11-2016 A4G23_RS24200 83e04b1ae668bdfdf1a3a330a8eca782 489 SUPERFAMILY SSF100950 136 300 5.44E-36 T 10-11-2016 A4G23_RS24200 83e04b1ae668bdfdf1a3a330a8eca782 489 SUPERFAMILY SSF100950 66 90 5.44E-36 T 10-11-2016 A4G23_RS24200 83e04b1ae668bdfdf1a3a330a8eca782 489 Gene3D G3DSA:3.40.50.10420 66 129 1.3E-45 T 10-11-2016 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain A4G23_RS24200 83e04b1ae668bdfdf1a3a330a8eca782 489 Gene3D G3DSA:3.40.50.10420 197 300 1.3E-45 T 10-11-2016 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain A4G23_RS24200 83e04b1ae668bdfdf1a3a330a8eca782 489 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 318 329 - T 10-11-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4G23_RS24200 83e04b1ae668bdfdf1a3a330a8eca782 489 Gene3D G3DSA:1.10.1060.10 313 399 5.0E-12 T 10-11-2016 A4G23_RS24200 83e04b1ae668bdfdf1a3a330a8eca782 489 Pfam PF13183 4Fe-4S dicluster domain 315 384 2.9E-9 T 10-11-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4G23_RS23800 0d0459112650928eb308a3d7f281badc 117 Pfam PF00581 Rhodanese-like domain 6 107 2.5E-14 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS23800 0d0459112650928eb308a3d7f281badc 117 ProSitePatterns PS00380 Rhodanese signature 1. 30 41 - T 10-11-2016 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 A4G23_RS23800 0d0459112650928eb308a3d7f281badc 117 SUPERFAMILY SSF52821 3 114 1.7E-24 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS23800 0d0459112650928eb308a3d7f281badc 117 Gene3D G3DSA:3.40.250.10 3 112 7.0E-25 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS23800 0d0459112650928eb308a3d7f281badc 117 SMART SM00450 5 111 4.8E-11 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS24900 1a392a6e27c2f09d689d5483215bb959 457 Pfam PF01593 Flavin containing amine oxidoreductase 13 441 2.9E-49 T 10-11-2016 IPR002937 Amine oxidase GO:0016491|GO:0055114 A4G23_RS24900 1a392a6e27c2f09d689d5483215bb959 457 Gene3D G3DSA:3.50.50.60 380 442 4.0E-34 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS24900 1a392a6e27c2f09d689d5483215bb959 457 Gene3D G3DSA:3.50.50.60 225 280 4.0E-34 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS24900 1a392a6e27c2f09d689d5483215bb959 457 Gene3D G3DSA:3.50.50.60 155 171 4.0E-34 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS24900 1a392a6e27c2f09d689d5483215bb959 457 Gene3D G3DSA:3.50.50.60 4 93 4.0E-34 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS24900 1a392a6e27c2f09d689d5483215bb959 457 TIGRFAM TIGR03467 HpnE: squalene-associated FAD-dependent desaturase 7 442 2.8E-138 T 10-11-2016 IPR017830 Squalene-associated FAD-dependent desaturase A4G23_RS24900 1a392a6e27c2f09d689d5483215bb959 457 SUPERFAMILY SSF51905 2 313 1.17E-54 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS24900 1a392a6e27c2f09d689d5483215bb959 457 SUPERFAMILY SSF51905 402 445 1.17E-54 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS24900 1a392a6e27c2f09d689d5483215bb959 457 PRINTS PR00757 Flavin-containing amine oxidase signature 423 440 1.1E-5 T 10-11-2016 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 A4G23_RS24900 1a392a6e27c2f09d689d5483215bb959 457 PRINTS PR00757 Flavin-containing amine oxidase signature 5 24 1.1E-5 T 10-11-2016 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 A4G23_RS27120 2b6b78cd64ddb266b2d1758860e4a621 400 SUPERFAMILY SSF63380 154 261 4.77E-27 T 10-11-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 A4G23_RS27120 2b6b78cd64ddb266b2d1758860e4a621 400 Gene3D G3DSA:1.10.490.10 2 144 1.5E-40 T 10-11-2016 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 A4G23_RS27120 2b6b78cd64ddb266b2d1758860e4a621 400 Pfam PF00042 Globin 8 103 1.5E-5 T 10-11-2016 IPR000971 Globin GO:0019825|GO:0020037 A4G23_RS27120 2b6b78cd64ddb266b2d1758860e4a621 400 SUPERFAMILY SSF46458 1 144 8.15E-31 T 10-11-2016 IPR009050 Globin-like A4G23_RS27120 2b6b78cd64ddb266b2d1758860e4a621 400 Pfam PF00175 Oxidoreductase NAD-binding domain 270 371 5.8E-10 T 10-11-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 A4G23_RS27120 2b6b78cd64ddb266b2d1758860e4a621 400 PRINTS PR00410 Phenol hydroxylase reductase family signature 186 198 1.0E-4 T 10-11-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 A4G23_RS27120 2b6b78cd64ddb266b2d1758860e4a621 400 PRINTS PR00410 Phenol hydroxylase reductase family signature 357 365 1.0E-4 T 10-11-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 A4G23_RS27120 2b6b78cd64ddb266b2d1758860e4a621 400 PRINTS PR00410 Phenol hydroxylase reductase family signature 269 288 1.0E-4 T 10-11-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 A4G23_RS27120 2b6b78cd64ddb266b2d1758860e4a621 400 Gene3D G3DSA:3.40.50.80 262 393 2.0E-27 T 10-11-2016 A4G23_RS27120 2b6b78cd64ddb266b2d1758860e4a621 400 Gene3D G3DSA:2.40.30.10 154 261 7.2E-31 T 10-11-2016 A4G23_RS27120 2b6b78cd64ddb266b2d1758860e4a621 400 SUPERFAMILY SSF52343 262 391 1.57E-28 T 10-11-2016 A4G23_RS27120 2b6b78cd64ddb266b2d1758860e4a621 400 Pfam PF00970 Oxidoreductase FAD-binding domain 159 259 1.3E-8 T 10-11-2016 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 A4G23_RS05780 29e1637e01e80ae71a29966a907c8703 435 Pfam PF06742 Protein of unknown function (DUF1214) 311 419 2.6E-33 T 10-11-2016 IPR010621 Domain of unknown function DUF1214 A4G23_RS05780 29e1637e01e80ae71a29966a907c8703 435 Gene3D G3DSA:2.60.120.600 270 434 8.7E-54 T 10-11-2016 IPR010621 Domain of unknown function DUF1214 A4G23_RS05780 29e1637e01e80ae71a29966a907c8703 435 Pfam PF06863 Protein of unknown function (DUF1254) 47 175 4.8E-46 T 10-11-2016 IPR010679 Domain of unknown function DUF1254 A4G23_RS05780 29e1637e01e80ae71a29966a907c8703 435 Gene3D G3DSA:1.10.3360.10 204 265 4.2E-6 T 10-11-2016 IPR023289 VPA0735-like domain A4G23_RS05780 29e1637e01e80ae71a29966a907c8703 435 SUPERFAMILY SSF160935 8 434 1.12E-120 T 10-11-2016 A4G23_RS05780 29e1637e01e80ae71a29966a907c8703 435 Gene3D G3DSA:2.60.40.1610 62 174 1.7E-18 T 10-11-2016 IPR010679 Domain of unknown function DUF1254 A4G23_RS18740 6b108770c0d2fc1a2c1eab3f897d0d8c 895 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 593 882 7.3E-31 T 10-11-2016 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD A4G23_RS18740 6b108770c0d2fc1a2c1eab3f897d0d8c 895 SUPERFAMILY SSF56112 280 430 4.77E-8 T 10-11-2016 IPR011009 Protein kinase-like domain A4G23_RS18740 6b108770c0d2fc1a2c1eab3f897d0d8c 895 Gene3D G3DSA:1.10.510.10 364 430 6.0E-5 T 10-11-2016 A4G23_RS19880 2083ab2cf922d20667f4b87a37627342 414 SUPERFAMILY SSF141523 252 383 1.26E-19 T 10-11-2016 A4G23_RS19880 2083ab2cf922d20667f4b87a37627342 414 Pfam PF03734 L,D-transpeptidase catalytic domain 251 383 1.9E-10 T 10-11-2016 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 A4G23_RS19880 2083ab2cf922d20667f4b87a37627342 414 Gene3D G3DSA:2.40.440.10 253 385 1.8E-16 T 10-11-2016 A4G23_RS20370 956091f53e8f7eb1cc4b87840ca646a4 77 Pfam PF01037 Lrp/AsnC ligand binding domain 6 74 1.1E-12 T 10-11-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A4G23_RS20370 956091f53e8f7eb1cc4b87840ca646a4 77 SUPERFAMILY SSF54909 2 75 6.57E-15 T 10-11-2016 IPR011008 Dimeric alpha-beta barrel A4G23_RS20370 956091f53e8f7eb1cc4b87840ca646a4 77 Gene3D G3DSA:3.30.70.920 4 75 1.1E-17 T 10-11-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A4G23_RS04725 65739a3b324e934531356f99bdb2e39f 307 SUPERFAMILY SSF55729 1 137 6.86E-22 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS04725 65739a3b324e934531356f99bdb2e39f 307 SUPERFAMILY SSF55729 118 299 1.6E-19 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS04725 65739a3b324e934531356f99bdb2e39f 307 Pfam PF00583 Acetyltransferase (GNAT) family 52 130 1.8E-9 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS04725 65739a3b324e934531356f99bdb2e39f 307 Gene3D G3DSA:3.40.630.30 149 299 1.1E-13 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS04725 65739a3b324e934531356f99bdb2e39f 307 Gene3D G3DSA:3.40.630.30 1 136 9.8E-23 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS23385 bf5fe398e8f467cb325a08b3b966145b 356 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 3 331 2.9E-75 T 10-11-2016 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 A4G23_RS23385 bf5fe398e8f467cb325a08b3b966145b 356 SUPERFAMILY SSF51395 1 355 1.47E-108 T 10-11-2016 A4G23_RS23385 bf5fe398e8f467cb325a08b3b966145b 356 Gene3D G3DSA:3.20.20.70 1 353 1.4E-114 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS21560 d7ac76b4240af1d5aa265434de32ba7d 226 Gene3D G3DSA:3.30.70.1450 146 218 1.4E-11 T 10-11-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A4G23_RS21560 d7ac76b4240af1d5aa265434de32ba7d 226 SUPERFAMILY SSF51735 1 145 2.05E-28 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS21560 d7ac76b4240af1d5aa265434de32ba7d 226 Pfam PF02080 TrkA-C domain 149 216 3.1E-12 T 10-11-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A4G23_RS21560 d7ac76b4240af1d5aa265434de32ba7d 226 SUPERFAMILY SSF116726 133 216 4.97E-14 T 10-11-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A4G23_RS21560 d7ac76b4240af1d5aa265434de32ba7d 226 Gene3D G3DSA:3.40.50.720 1 132 1.2E-30 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS21560 d7ac76b4240af1d5aa265434de32ba7d 226 Pfam PF02254 TrkA-N domain 3 118 3.0E-24 T 10-11-2016 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 A4G23_RS00840 ef5324e9174ac6247be99c19530c7fa3 868 Pfam PF01752 Collagenase 368 655 4.5E-120 T 10-11-2016 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 A4G23_RS00840 ef5324e9174ac6247be99c19530c7fa3 868 Pfam PF04151 Bacterial pre-peptidase C-terminal domain 792 853 9.3E-6 T 10-11-2016 IPR007280 Peptidase, C-terminal, archaeal/bacterial A4G23_RS00840 ef5324e9174ac6247be99c19530c7fa3 868 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 528 546 2.0E-38 T 10-11-2016 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 A4G23_RS00840 ef5324e9174ac6247be99c19530c7fa3 868 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 551 566 2.0E-38 T 10-11-2016 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 A4G23_RS00840 ef5324e9174ac6247be99c19530c7fa3 868 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 193 211 2.0E-38 T 10-11-2016 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 A4G23_RS00840 ef5324e9174ac6247be99c19530c7fa3 868 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 467 481 2.0E-38 T 10-11-2016 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 A4G23_RS00840 ef5324e9174ac6247be99c19530c7fa3 868 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 485 501 2.0E-38 T 10-11-2016 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 A4G23_RS00840 ef5324e9174ac6247be99c19530c7fa3 868 Pfam PF00801 PKD domain 681 744 2.6E-12 T 10-11-2016 IPR000601 PKD domain A4G23_RS00840 ef5324e9174ac6247be99c19530c7fa3 868 Pfam PF08453 Peptidase family M9 N-terminal 127 308 8.9E-69 T 10-11-2016 IPR013661 Peptidase M9, collagenase, N-terminal domain A4G23_RS00840 ef5324e9174ac6247be99c19530c7fa3 868 SMART SM00089 677 755 8.4E-22 T 10-11-2016 IPR022409 PKD/Chitinase domain A4G23_RS00840 ef5324e9174ac6247be99c19530c7fa3 868 Gene3D G3DSA:2.60.40.670 673 754 2.7E-21 T 10-11-2016 IPR000601 PKD domain A4G23_RS00840 ef5324e9174ac6247be99c19530c7fa3 868 SUPERFAMILY SSF49299 673 753 7.06E-22 T 10-11-2016 IPR000601 PKD domain A4G23_RS22960 178a471588cc4b386203fd8dab7dfeed 466 Gene3D G3DSA:3.50.50.60 12 128 5.7E-22 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS22960 178a471588cc4b386203fd8dab7dfeed 466 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 345 446 1.8E-19 T 10-11-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A4G23_RS22960 178a471588cc4b386203fd8dab7dfeed 466 Gene3D G3DSA:3.50.50.60 129 331 5.0E-45 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS22960 178a471588cc4b386203fd8dab7dfeed 466 SUPERFAMILY SSF51905 12 209 1.02E-45 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS22960 178a471588cc4b386203fd8dab7dfeed 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 13 35 2.1E-16 T 10-11-2016 A4G23_RS22960 178a471588cc4b386203fd8dab7dfeed 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 292 299 2.1E-16 T 10-11-2016 A4G23_RS22960 178a471588cc4b386203fd8dab7dfeed 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 250 264 2.1E-16 T 10-11-2016 A4G23_RS22960 178a471588cc4b386203fd8dab7dfeed 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 164 189 2.1E-16 T 10-11-2016 A4G23_RS22960 178a471588cc4b386203fd8dab7dfeed 466 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 13 322 4.3E-58 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS22960 178a471588cc4b386203fd8dab7dfeed 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 164 182 1.3E-17 T 10-11-2016 A4G23_RS22960 178a471588cc4b386203fd8dab7dfeed 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 14 33 1.3E-17 T 10-11-2016 A4G23_RS22960 178a471588cc4b386203fd8dab7dfeed 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 249 265 1.3E-17 T 10-11-2016 A4G23_RS22960 178a471588cc4b386203fd8dab7dfeed 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 117 135 1.3E-17 T 10-11-2016 A4G23_RS22960 178a471588cc4b386203fd8dab7dfeed 466 SUPERFAMILY SSF55424 338 458 1.34E-31 T 10-11-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 A4G23_RS22960 178a471588cc4b386203fd8dab7dfeed 466 SUPERFAMILY SSF51905 163 331 2.34E-27 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS22960 178a471588cc4b386203fd8dab7dfeed 466 Gene3D G3DSA:3.30.390.30 350 459 3.8E-37 T 10-11-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A4G23_RS06345 efe375250cfe24e36f8403ef7d6ceb53 214 SUPERFAMILY SSF51391 8 210 2.22E-58 T 10-11-2016 IPR022998 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A4G23_RS06345 efe375250cfe24e36f8403ef7d6ceb53 214 Pfam PF02581 Thiamine monophosphate synthase/TENI 14 195 6.1E-48 T 10-11-2016 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A4G23_RS06345 efe375250cfe24e36f8403ef7d6ceb53 214 Gene3D G3DSA:3.20.20.70 8 213 3.4E-68 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS06345 efe375250cfe24e36f8403ef7d6ceb53 214 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 11 213 23.315 T 10-11-2016 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A4G23_RS06345 efe375250cfe24e36f8403ef7d6ceb53 214 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 13 207 1.1E-56 T 10-11-2016 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A4G23_RS05345 82282b27f6f2aa43aec422476aebddc6 369 SUPERFAMILY SSF53383 15 352 1.85E-63 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS05345 82282b27f6f2aa43aec422476aebddc6 369 Gene3D G3DSA:3.90.1150.10 241 353 7.2E-17 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS05345 82282b27f6f2aa43aec422476aebddc6 369 PIRSF PIRSF000524 14 367 2.5E-63 T 10-11-2016 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661 A4G23_RS05345 82282b27f6f2aa43aec422476aebddc6 369 Pfam PF00266 Aminotransferase class-V 20 342 3.0E-25 T 10-11-2016 IPR000192 Aminotransferase class V domain A4G23_RS05345 82282b27f6f2aa43aec422476aebddc6 369 Gene3D G3DSA:3.40.640.10 14 239 4.3E-43 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS20675 e551e7cf789b53634a2e5df72a82a5c8 341 SUPERFAMILY SSF51556 7 338 4.4E-78 T 10-11-2016 IPR032466 Metal-dependent hydrolase A4G23_RS20675 e551e7cf789b53634a2e5df72a82a5c8 341 Gene3D G3DSA:3.20.20.140 7 334 4.5E-96 T 10-11-2016 A4G23_RS20675 e551e7cf789b53634a2e5df72a82a5c8 341 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 11 329 3.5E-83 T 10-11-2016 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 A4G23_RS20675 e551e7cf789b53634a2e5df72a82a5c8 341 Pfam PF00962 Adenosine/AMP deaminase 11 328 5.6E-88 T 10-11-2016 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 A4G23_RS18650 8d4b09b80c9ca503bd1619f66cf27642 244 SUPERFAMILY SSF47240 34 155 4.82E-9 T 10-11-2016 IPR009078 Ferritin-like superfamily A4G23_RS18650 8d4b09b80c9ca503bd1619f66cf27642 244 Pfam PF13794 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like 28 212 1.4E-94 T 10-11-2016 A4G23_RS18650 8d4b09b80c9ca503bd1619f66cf27642 244 Gene3D G3DSA:1.20.1260.10 31 156 2.0E-6 T 10-11-2016 IPR012347 Ferritin-related A4G23_RS26570 f686aea43f992b69e50225bc1d51ee28 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 31 261 8.7E-48 T 10-11-2016 A4G23_RS26570 f686aea43f992b69e50225bc1d51ee28 263 Gene3D G3DSA:3.40.50.720 17 262 1.7E-72 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS26570 f686aea43f992b69e50225bc1d51ee28 263 SUPERFAMILY SSF51735 18 262 1.95E-70 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS26570 f686aea43f992b69e50225bc1d51ee28 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 1.8E-38 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS26570 f686aea43f992b69e50225bc1d51ee28 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.8E-38 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS26570 f686aea43f992b69e50225bc1d51ee28 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 23 40 1.8E-38 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS26570 f686aea43f992b69e50225bc1d51ee28 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 224 244 1.8E-38 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS26570 f686aea43f992b69e50225bc1d51ee28 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.8E-38 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS26570 f686aea43f992b69e50225bc1d51ee28 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 1.8E-38 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS26570 f686aea43f992b69e50225bc1d51ee28 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 1.2E-10 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS26570 f686aea43f992b69e50225bc1d51ee28 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 1.2E-10 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS26570 f686aea43f992b69e50225bc1d51ee28 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 1.2E-10 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS26570 f686aea43f992b69e50225bc1d51ee28 263 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 10-11-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4G23_RS26570 f686aea43f992b69e50225bc1d51ee28 263 TIGRFAM TIGR01963 PHB_DH: 3-hydroxybutyrate dehydrogenase 22 262 5.6E-93 T 10-11-2016 IPR011294 3-hydroxybutyrate dehydrogenase GO:0003858|GO:0055114 A4G23_RS05110 234d18319f1d240cb8f98309dc2b6079 237 SUPERFAMILY SSF46785 7 78 1.94E-23 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS05110 234d18319f1d240cb8f98309dc2b6079 237 Gene3D G3DSA:1.10.10.10 8 77 1.8E-27 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS05110 234d18319f1d240cb8f98309dc2b6079 237 SMART SM00895 95 218 8.1E-18 T 10-11-2016 IPR011711 GntR, C-terminal A4G23_RS05110 234d18319f1d240cb8f98309dc2b6079 237 SUPERFAMILY SSF48008 92 213 8.37E-23 T 10-11-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal A4G23_RS05110 234d18319f1d240cb8f98309dc2b6079 237 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 5.5E-9 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS05110 234d18319f1d240cb8f98309dc2b6079 237 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 5.5E-9 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS05110 234d18319f1d240cb8f98309dc2b6079 237 Pfam PF07729 FCD domain 97 212 2.0E-22 T 10-11-2016 IPR011711 GntR, C-terminal A4G23_RS05110 234d18319f1d240cb8f98309dc2b6079 237 Gene3D G3DSA:1.20.120.530 91 213 2.5E-23 T 10-11-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal A4G23_RS05110 234d18319f1d240cb8f98309dc2b6079 237 SMART SM00345 15 74 3.2E-20 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS05110 234d18319f1d240cb8f98309dc2b6079 237 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 74 1.6E-20 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS20755 b026c7834c2f962b008880b5be00aad3 245 Gene3D G3DSA:3.40.50.720 1 244 1.1E-69 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS20755 b026c7834c2f962b008880b5be00aad3 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 1 18 4.6E-39 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS20755 b026c7834c2f962b008880b5be00aad3 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 4.6E-39 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS20755 b026c7834c2f962b008880b5be00aad3 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 4.6E-39 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS20755 b026c7834c2f962b008880b5be00aad3 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 4.6E-39 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS20755 b026c7834c2f962b008880b5be00aad3 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 4.6E-39 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS20755 b026c7834c2f962b008880b5be00aad3 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 4.6E-39 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS20755 b026c7834c2f962b008880b5be00aad3 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 9 244 1.1E-53 T 10-11-2016 A4G23_RS20755 b026c7834c2f962b008880b5be00aad3 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 8.2E-8 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS20755 b026c7834c2f962b008880b5be00aad3 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 8.2E-8 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS20755 b026c7834c2f962b008880b5be00aad3 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 8.2E-8 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS20755 b026c7834c2f962b008880b5be00aad3 245 SUPERFAMILY SSF51735 1 244 2.39E-67 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS08850 a7abe743f120823f211214142ae7ddfc 412 TIGRFAM TIGR04541 thiaminase_BcmE: thiamine pyridinylase 21 368 6.1E-61 T 10-11-2016 IPR030901 Thiamine pyridinylase KEGG: 00730+2.5.1.2 A4G23_RS08850 a7abe743f120823f211214142ae7ddfc 412 SUPERFAMILY SSF53850 25 355 1.58E-20 T 10-11-2016 A4G23_RS08850 a7abe743f120823f211214142ae7ddfc 412 Gene3D G3DSA:3.40.190.10 136 316 9.3E-31 T 10-11-2016 A4G23_RS08850 a7abe743f120823f211214142ae7ddfc 412 Gene3D G3DSA:3.40.190.10 25 135 5.1E-15 T 10-11-2016 A4G23_RS04395 3d6ca5fafffec45dff2863f1651db513 409 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 40 51 3.3E-18 T 10-11-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A4G23_RS04395 3d6ca5fafffec45dff2863f1651db513 409 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 76 85 3.3E-18 T 10-11-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A4G23_RS04395 3d6ca5fafffec45dff2863f1651db513 409 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 241 262 3.3E-18 T 10-11-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A4G23_RS04395 3d6ca5fafffec45dff2863f1651db513 409 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 210 228 3.3E-18 T 10-11-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A4G23_RS04395 3d6ca5fafffec45dff2863f1651db513 409 Hamap MF_01697 L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase [mshC]. 9 409 53.897 T 10-11-2016 IPR017812 Mycothiol ligase MshC GO:0010125|GO:0035446 A4G23_RS04395 3d6ca5fafffec45dff2863f1651db513 409 TIGRFAM TIGR03447 mycothiol_MshC: cysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase 2 409 4.4E-204 T 10-11-2016 IPR017812 Mycothiol ligase MshC GO:0010125|GO:0035446 A4G23_RS04395 3d6ca5fafffec45dff2863f1651db513 409 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 39 333 6.5E-80 T 10-11-2016 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 A4G23_RS04395 3d6ca5fafffec45dff2863f1651db513 409 Gene3D G3DSA:1.20.120.640 332 379 5.3E-4 T 10-11-2016 A4G23_RS04395 3d6ca5fafffec45dff2863f1651db513 409 Gene3D G3DSA:3.40.50.620 37 326 4.9E-74 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS04395 3d6ca5fafffec45dff2863f1651db513 409 SUPERFAMILY SSF52374 33 333 1.26E-67 T 10-11-2016 A4G23_RS23130 3ba78ad3d2d4e7fa1e2ad1d1a0f5980c 372 Gene3D G3DSA:3.30.470.20 239 327 6.4E-5 T 10-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 A4G23_RS23130 3ba78ad3d2d4e7fa1e2ad1d1a0f5980c 372 Gene3D G3DSA:3.30.1490.20 110 178 3.6E-6 T 10-11-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A4G23_RS23130 3ba78ad3d2d4e7fa1e2ad1d1a0f5980c 372 SUPERFAMILY SSF56059 122 185 7.07E-10 T 10-11-2016 A4G23_RS23130 3ba78ad3d2d4e7fa1e2ad1d1a0f5980c 372 SUPERFAMILY SSF56059 213 328 7.07E-10 T 10-11-2016 A4G23_RS18410 ec7f34da9d1fe981063a86e69b101eb8 348 SUPERFAMILY SSF161098 128 332 1.1E-27 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS18410 ec7f34da9d1fe981063a86e69b101eb8 348 Gene3D G3DSA:1.10.3720.10 124 344 6.8E-28 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS18410 ec7f34da9d1fe981063a86e69b101eb8 348 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 39 75 6.8E-9 T 10-11-2016 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A4G23_RS18410 ec7f34da9d1fe981063a86e69b101eb8 348 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 151 346 9.3E-30 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS24195 31114c50af7ec08f235545ddcb1ee8e7 227 Gene3D G3DSA:3.40.50.10420 42 214 1.9E-52 T 10-11-2016 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain A4G23_RS24195 31114c50af7ec08f235545ddcb1ee8e7 227 Pfam PF02589 Uncharacterised ACR, YkgG family COG1556 104 213 5.6E-20 T 10-11-2016 IPR003741 LUD domain A4G23_RS24195 31114c50af7ec08f235545ddcb1ee8e7 227 SUPERFAMILY SSF100950 43 214 1.72E-36 T 10-11-2016 A4G23_RS24020 be340c856c45dc4b85b59b7d171fdf46 174 Pfam PF01613 Flavin reductase like domain 11 152 3.6E-30 T 10-11-2016 IPR002563 Flavin reductase like domain GO:0010181 A4G23_RS24020 be340c856c45dc4b85b59b7d171fdf46 174 SMART SM00903 11 153 5.1E-43 T 10-11-2016 IPR002563 Flavin reductase like domain GO:0010181 A4G23_RS24020 be340c856c45dc4b85b59b7d171fdf46 174 SUPERFAMILY SSF50475 3 152 5.4E-40 T 10-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 A4G23_RS24020 be340c856c45dc4b85b59b7d171fdf46 174 Gene3D G3DSA:2.30.110.10 2 152 4.7E-44 T 10-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 A4G23_RS25490 4583d018d9f8025a9ef95f0bb6a23e9a 105 Pfam PF12802 MarR family 17 65 1.8E-7 T 10-11-2016 A4G23_RS25490 4583d018d9f8025a9ef95f0bb6a23e9a 105 SUPERFAMILY SSF46785 17 73 5.3E-10 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS25490 4583d018d9f8025a9ef95f0bb6a23e9a 105 Gene3D G3DSA:1.10.10.10 17 72 3.6E-11 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS25280 ce855230683b596388a5baa635aa845d 660 SUPERFAMILY SSF53271 159 276 1.32E-7 T 10-11-2016 IPR029057 Phosphoribosyltransferase-like A4G23_RS25280 ce855230683b596388a5baa635aa845d 660 Gene3D G3DSA:3.40.50.2020 139 266 6.2E-4 T 10-11-2016 IPR029057 Phosphoribosyltransferase-like A4G23_RS07475 9fca80522fa8ef2ab56b7cd0a9f08f55 156 Pfam PF13411 MerR HTH family regulatory protein 33 94 3.6E-15 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS07475 9fca80522fa8ef2ab56b7cd0a9f08f55 156 Gene3D G3DSA:1.10.1660.10 33 149 2.0E-29 T 10-11-2016 A4G23_RS07475 9fca80522fa8ef2ab56b7cd0a9f08f55 156 ProSitePatterns PS00552 MerR-type HTH domain signature. 36 58 - T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS07475 9fca80522fa8ef2ab56b7cd0a9f08f55 156 SMART SM00422 33 102 2.5E-17 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS07475 9fca80522fa8ef2ab56b7cd0a9f08f55 156 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 69 89 7.6E-5 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS07475 9fca80522fa8ef2ab56b7cd0a9f08f55 156 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 45 58 7.6E-5 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS07475 9fca80522fa8ef2ab56b7cd0a9f08f55 156 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 34 45 7.6E-5 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS07475 9fca80522fa8ef2ab56b7cd0a9f08f55 156 SUPERFAMILY SSF46955 33 147 1.1E-28 T 10-11-2016 IPR009061 Putative DNA-binding domain A4G23_RS25325 63df0aa21280073f65e82727d634d16d 421 SUPERFAMILY SSF53756 24 402 1.4E-67 T 10-11-2016 A4G23_RS25325 63df0aa21280073f65e82727d634d16d 421 Pfam PF13579 Glycosyl transferase 4-like domain 26 203 2.1E-20 T 10-11-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A4G23_RS25325 63df0aa21280073f65e82727d634d16d 421 Pfam PF00534 Glycosyl transferases group 1 219 382 4.8E-26 T 10-11-2016 IPR001296 Glycosyl transferase, family 1 A4G23_RS25325 63df0aa21280073f65e82727d634d16d 421 Gene3D G3DSA:3.40.50.2000 216 385 2.7E-31 T 10-11-2016 A4G23_RS02125 caa9bcb13ff6f9e3bcaaa3c4b6e19d1d 1455 Pfam PF11847 Domain of unknown function (DUF3367) 39 693 1.5E-218 T 10-11-2016 IPR021798 Protein of unknown function DUF3367 MetaCyc: PWY-6397 A4G23_RS02125 caa9bcb13ff6f9e3bcaaa3c4b6e19d1d 1455 Gene3D G3DSA:2.60.120.260 721 854 1.1E-7 T 10-11-2016 IPR008979 Galactose-binding domain-like A4G23_RS02125 caa9bcb13ff6f9e3bcaaa3c4b6e19d1d 1455 SUPERFAMILY SSF49785 725 855 3.87E-7 T 10-11-2016 IPR008979 Galactose-binding domain-like A4G23_RS20545 e5fc1c75422fb7fbced594da4ee2c6ef 170 ProSitePatterns PS00893 Nudix box signature. 48 69 - T 10-11-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A4G23_RS20545 e5fc1c75422fb7fbced594da4ee2c6ef 170 Gene3D G3DSA:3.90.79.10 12 157 1.4E-27 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS20545 e5fc1c75422fb7fbced594da4ee2c6ef 170 SUPERFAMILY SSF55811 10 136 3.79E-22 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS20545 e5fc1c75422fb7fbced594da4ee2c6ef 170 Pfam PF00293 NUDIX domain 12 137 1.0E-20 T 10-11-2016 IPR000086 NUDIX hydrolase domain GO:0016787 A4G23_RS20545 e5fc1c75422fb7fbced594da4ee2c6ef 170 PRINTS PR00502 NUDIX hydrolase family signature 43 57 1.7E-6 T 10-11-2016 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A4G23_RS20545 e5fc1c75422fb7fbced594da4ee2c6ef 170 PRINTS PR00502 NUDIX hydrolase family signature 57 72 1.7E-6 T 10-11-2016 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A4G23_RS24600 45f34785e05cfe721be39e95a280dc8a 225 SUPERFAMILY SSF49695 130 220 7.44E-6 T 10-11-2016 IPR011024 Gamma-crystallin-related A4G23_RS24600 45f34785e05cfe721be39e95a280dc8a 225 Gene3D G3DSA:2.60.20.10 131 220 1.4E-7 T 10-11-2016 A4G23_RS15990 18fea35bda003f481a2ff8b3d164ab66 345 Gene3D G3DSA:3.40.50.1820 65 338 8.8E-34 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS15990 18fea35bda003f481a2ff8b3d164ab66 345 Pfam PF00756 Putative esterase 97 290 3.9E-14 T 10-11-2016 IPR000801 Putative esterase Reactome: R-HSA-156590 A4G23_RS15990 18fea35bda003f481a2ff8b3d164ab66 345 SUPERFAMILY SSF53474 86 319 1.74E-24 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS09515 6a9ad091b00d1900449974876eedbb29 537 Pfam PF10708 Protein of unknown function (DUF2510) 15 45 3.2E-9 T 10-11-2016 IPR018929 Domain of unknown function DUF2510 A4G23_RS09515 6a9ad091b00d1900449974876eedbb29 537 Pfam PF06271 RDD family 380 531 2.1E-23 T 10-11-2016 IPR010432 RDD A4G23_RS19025 d6b754ac2b46fa0cb3f758c2dc555aec 507 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 43 330 2.7E-76 T 10-11-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4G23_RS19025 d6b754ac2b46fa0cb3f758c2dc555aec 507 Gene3D G3DSA:3.20.20.300 20 334 2.3E-95 T 10-11-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4G23_RS19025 d6b754ac2b46fa0cb3f758c2dc555aec 507 SUPERFAMILY SSF51445 40 335 6.0E-82 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS19025 d6b754ac2b46fa0cb3f758c2dc555aec 507 PRINTS PR00133 Glycosyl hydrolase family 3 signature 247 265 6.7E-6 T 10-11-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4G23_RS19025 d6b754ac2b46fa0cb3f758c2dc555aec 507 PRINTS PR00133 Glycosyl hydrolase family 3 signature 93 112 6.7E-6 T 10-11-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4G23_RS19025 d6b754ac2b46fa0cb3f758c2dc555aec 507 PRINTS PR00133 Glycosyl hydrolase family 3 signature 171 187 6.7E-6 T 10-11-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A4G23_RS18555 de8c1f506c7b17d762716304a606e99e 233 Gene3D G3DSA:3.40.50.150 35 232 1.4E-52 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS18555 de8c1f506c7b17d762716304a606e99e 233 Pfam PF01596 O-methyltransferase 58 230 1.5E-24 T 10-11-2016 IPR002935 O-methyltransferase, family 3 GO:0008171 A4G23_RS18555 de8c1f506c7b17d762716304a606e99e 233 SUPERFAMILY SSF53335 45 232 1.14E-35 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS24440 56fc8c7ec535c8fa3678bde09066b2a2 263 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 37 256 3.5E-28 T 10-11-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS24440 56fc8c7ec535c8fa3678bde09066b2a2 263 Gene3D G3DSA:1.10.10.10 201 258 5.0E-9 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS24440 56fc8c7ec535c8fa3678bde09066b2a2 263 Gene3D G3DSA:1.10.601.10 17 107 1.8E-19 T 10-11-2016 A4G23_RS24440 56fc8c7ec535c8fa3678bde09066b2a2 263 SUPERFAMILY SSF88659 182 258 2.06E-15 T 10-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS24440 56fc8c7ec535c8fa3678bde09066b2a2 263 Pfam PF04542 Sigma-70 region 2 41 109 1.3E-16 T 10-11-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS24440 56fc8c7ec535c8fa3678bde09066b2a2 263 Gene3D G3DSA:1.10.10.10 109 163 5.5E-17 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS24440 56fc8c7ec535c8fa3678bde09066b2a2 263 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 34 258 1.7E-85 T 10-11-2016 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS24440 56fc8c7ec535c8fa3678bde09066b2a2 263 PRINTS PR00046 Major sigma-70 factor signature 228 243 3.1E-6 T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS24440 56fc8c7ec535c8fa3678bde09066b2a2 263 PRINTS PR00046 Major sigma-70 factor signature 64 77 3.1E-6 T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS24440 56fc8c7ec535c8fa3678bde09066b2a2 263 PRINTS PR00046 Major sigma-70 factor signature 211 223 3.1E-6 T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS24440 56fc8c7ec535c8fa3678bde09066b2a2 263 Pfam PF04545 Sigma-70, region 4 208 256 3.8E-17 T 10-11-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS24440 56fc8c7ec535c8fa3678bde09066b2a2 263 SUPERFAMILY SSF88659 113 189 2.53E-10 T 10-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS24440 56fc8c7ec535c8fa3678bde09066b2a2 263 SUPERFAMILY SSF88946 31 110 1.57E-25 T 10-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS24960 e9edb8d0680df8511efc348efcb6b29f 209 Gene3D G3DSA:3.40.50.720 1 135 2.8E-31 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS24960 e9edb8d0680df8511efc348efcb6b29f 209 SUPERFAMILY SSF51735 1 126 2.97E-30 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS24960 e9edb8d0680df8511efc348efcb6b29f 209 Pfam PF02080 TrkA-C domain 144 207 1.6E-12 T 10-11-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A4G23_RS24960 e9edb8d0680df8511efc348efcb6b29f 209 SUPERFAMILY SSF116726 123 207 9.68E-17 T 10-11-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A4G23_RS24960 e9edb8d0680df8511efc348efcb6b29f 209 Gene3D G3DSA:3.30.70.1450 145 207 1.4E-12 T 10-11-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A4G23_RS24960 e9edb8d0680df8511efc348efcb6b29f 209 Pfam PF02254 TrkA-N domain 1 113 8.3E-25 T 10-11-2016 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 A4G23_RS13845 d2b1a419a2621d4ab8b1dde54b4f4b8d 323 Pfam PF02810 SEC-C motif 28 44 5.4E-8 T 10-11-2016 IPR004027 SEC-C motif A4G23_RS13845 d2b1a419a2621d4ab8b1dde54b4f4b8d 323 SUPERFAMILY SSF103642 25 44 9.32E-7 T 10-11-2016 A4G23_RS13845 d2b1a419a2621d4ab8b1dde54b4f4b8d 323 Gene3D G3DSA:3.10.450.50 9 44 2.2E-8 T 10-11-2016 IPR032710 NTF2-like domain A4G23_RS20610 9c55ae082cbcebf24adf23bc37d9cf5d 370 Pfam PF04055 Radical SAM superfamily 126 297 3.1E-16 T 10-11-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 A4G23_RS20610 9c55ae082cbcebf24adf23bc37d9cf5d 370 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 21 370 67.108 T 10-11-2016 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A4G23_RS20610 9c55ae082cbcebf24adf23bc37d9cf5d 370 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 22 369 1.8E-96 T 10-11-2016 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A4G23_RS20610 9c55ae082cbcebf24adf23bc37d9cf5d 370 PIRSF PIRSF006004 16 370 6.0E-123 T 10-11-2016 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A4G23_RS20610 9c55ae082cbcebf24adf23bc37d9cf5d 370 SUPERFAMILY SSF102114 115 344 1.31E-17 T 10-11-2016 A4G23_RS20610 9c55ae082cbcebf24adf23bc37d9cf5d 370 Gene3D G3DSA:3.20.20.70 122 341 4.7E-16 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS03705 8893ce129a124a91670c7924caf4b6ce 362 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 18 305 23.465 T 10-11-2016 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 A4G23_RS03705 8893ce129a124a91670c7924caf4b6ce 362 Pfam PF02355 Protein export membrane protein 115 303 2.9E-64 T 10-11-2016 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial A4G23_RS03705 8893ce129a124a91670c7924caf4b6ce 362 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 46 294 3.4E-71 T 10-11-2016 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 A4G23_RS03705 8893ce129a124a91670c7924caf4b6ce 362 Gene3D G3DSA:1.20.1640.10 103 309 1.8E-19 T 10-11-2016 A4G23_RS03705 8893ce129a124a91670c7924caf4b6ce 362 Pfam PF07549 SecD/SecF GG Motif 41 61 3.0E-5 T 10-11-2016 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site A4G23_RS03705 8893ce129a124a91670c7924caf4b6ce 362 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 71 291 1.0E-50 T 10-11-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A4G23_RS03705 8893ce129a124a91670c7924caf4b6ce 362 PRINTS PR01755 Bacterial translocase SecF protein signature 154 168 6.7E-22 T 10-11-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A4G23_RS03705 8893ce129a124a91670c7924caf4b6ce 362 PRINTS PR01755 Bacterial translocase SecF protein signature 45 60 6.7E-22 T 10-11-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A4G23_RS03705 8893ce129a124a91670c7924caf4b6ce 362 PRINTS PR01755 Bacterial translocase SecF protein signature 237 252 6.7E-22 T 10-11-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A4G23_RS03705 8893ce129a124a91670c7924caf4b6ce 362 PRINTS PR01755 Bacterial translocase SecF protein signature 202 220 6.7E-22 T 10-11-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A4G23_RS03705 8893ce129a124a91670c7924caf4b6ce 362 SUPERFAMILY SSF82866 119 304 1.96E-27 T 10-11-2016 A4G23_RS16630 02233cfd975fce3b12709b9a46c1fbf2 115 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 111 30.192 T 10-11-2016 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS16630 02233cfd975fce3b12709b9a46c1fbf2 115 ProSitePatterns PS00464 Ribosomal protein L22 signature. 84 108 - T 10-11-2016 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS16630 02233cfd975fce3b12709b9a46c1fbf2 115 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 108 4.0E-45 T 10-11-2016 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS16630 02233cfd975fce3b12709b9a46c1fbf2 115 Pfam PF00237 Ribosomal protein L22p/L17e 8 108 3.6E-33 T 10-11-2016 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 A4G23_RS16630 02233cfd975fce3b12709b9a46c1fbf2 115 Gene3D G3DSA:3.90.470.10 1 112 7.6E-43 T 10-11-2016 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 A4G23_RS16630 02233cfd975fce3b12709b9a46c1fbf2 115 SUPERFAMILY SSF54843 1 112 1.44E-42 T 10-11-2016 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 A4G23_RS20565 1a90841d9c91e5ffc0351a0789192341 379 SUPERFAMILY SSF102405 80 287 8.09E-36 T 10-11-2016 A4G23_RS20565 1a90841d9c91e5ffc0351a0789192341 379 Pfam PF02481 DNA recombination-mediator protein A 73 279 2.4E-65 T 10-11-2016 IPR003488 DNA recombination-mediator protein A GO:0009294 A4G23_RS20565 1a90841d9c91e5ffc0351a0789192341 379 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 71 286 6.1E-61 T 10-11-2016 IPR003488 DNA recombination-mediator protein A GO:0009294 A4G23_RS20565 1a90841d9c91e5ffc0351a0789192341 379 Gene3D G3DSA:3.40.50.450 114 258 3.7E-12 T 10-11-2016 A4G23_RS21665 fe884948022a3ee85cda437001227b4d 458 Gene3D G3DSA:1.20.1250.20 45 224 8.2E-18 T 10-11-2016 A4G23_RS21665 fe884948022a3ee85cda437001227b4d 458 Gene3D G3DSA:1.20.1250.20 252 425 5.2E-6 T 10-11-2016 A4G23_RS21665 fe884948022a3ee85cda437001227b4d 458 SUPERFAMILY SSF103473 42 427 1.44E-38 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS21665 fe884948022a3ee85cda437001227b4d 458 Pfam PF05977 Transmembrane secretion effector 42 336 9.0E-19 T 10-11-2016 IPR010290 Transmembrane secretion effector A4G23_RS09655 edb9fb875c22004552b6e9a0f375687e 186 Gene3D G3DSA:3.40.1740.10 127 173 8.8E-28 T 10-11-2016 A4G23_RS09655 edb9fb875c22004552b6e9a0f375687e 186 Gene3D G3DSA:3.40.1740.10 2 44 8.8E-28 T 10-11-2016 A4G23_RS09655 edb9fb875c22004552b6e9a0f375687e 186 Pfam PF02622 Uncharacterized ACR, COG1678 16 169 8.4E-35 T 10-11-2016 IPR003774 Protein of unknown function UPF0301 A4G23_RS09655 edb9fb875c22004552b6e9a0f375687e 186 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 5 183 26.682 T 10-11-2016 IPR003774 Protein of unknown function UPF0301 A4G23_RS09655 edb9fb875c22004552b6e9a0f375687e 186 SUPERFAMILY SSF143456 4 180 1.44E-46 T 10-11-2016 A4G23_RS13880 b6ac404feb8e74f77f02bd77ffea1b13 1542 Gene3D G3DSA:3.40.50.2300 1416 1513 7.3E-12 T 10-11-2016 A4G23_RS13880 b6ac404feb8e74f77f02bd77ffea1b13 1542 SUPERFAMILY SSF47384 277 360 4.32E-5 T 10-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4G23_RS13880 b6ac404feb8e74f77f02bd77ffea1b13 1542 Pfam PF00989 PAS fold 113 224 6.2E-14 T 10-11-2016 IPR013767 PAS fold GO:0006355 A4G23_RS13880 b6ac404feb8e74f77f02bd77ffea1b13 1542 Pfam PF00072 Response regulator receiver domain 1420 1501 8.4E-5 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS13880 b6ac404feb8e74f77f02bd77ffea1b13 1542 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 112 224 3.1E-10 T 10-11-2016 IPR000014 PAS domain A4G23_RS13880 b6ac404feb8e74f77f02bd77ffea1b13 1542 SUPERFAMILY SSF52172 1415 1505 4.7E-12 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS13880 b6ac404feb8e74f77f02bd77ffea1b13 1542 SUPERFAMILY SSF55785 100 224 1.92E-19 T 10-11-2016 IPR000014 PAS domain A4G23_RS13880 b6ac404feb8e74f77f02bd77ffea1b13 1542 Gene3D G3DSA:3.30.450.20 104 224 1.3E-22 T 10-11-2016 A4G23_RS13880 b6ac404feb8e74f77f02bd77ffea1b13 1542 SMART SM00091 109 177 5.1E-7 T 10-11-2016 IPR000014 PAS domain A4G23_RS23780 345d62e1064f8c15544e054f1ccf4ac0 310 SUPERFAMILY SSF46785 3 106 4.13E-21 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS23780 345d62e1064f8c15544e054f1ccf4ac0 310 Gene3D G3DSA:3.40.190.10 151 191 2.9E-4 T 10-11-2016 A4G23_RS23780 345d62e1064f8c15544e054f1ccf4ac0 310 Pfam PF03466 LysR substrate binding domain 147 305 4.5E-11 T 10-11-2016 IPR005119 LysR, substrate-binding A4G23_RS23780 345d62e1064f8c15544e054f1ccf4ac0 310 Gene3D G3DSA:3.40.190.10 192 276 9.0E-8 T 10-11-2016 A4G23_RS23780 345d62e1064f8c15544e054f1ccf4ac0 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 6.3E-18 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS23780 345d62e1064f8c15544e054f1ccf4ac0 310 SUPERFAMILY SSF53850 146 306 7.96E-10 T 10-11-2016 A4G23_RS23780 345d62e1064f8c15544e054f1ccf4ac0 310 Gene3D G3DSA:1.10.10.10 2 80 3.4E-21 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS11105 92b61d8b9f18a8252d47a928db22dda3 246 Gene3D G3DSA:1.10.3630.10 3 212 3.8E-41 T 10-11-2016 A4G23_RS11105 92b61d8b9f18a8252d47a928db22dda3 246 Pfam PF05719 Golgi phosphoprotein 3 (GPP34) 8 202 5.4E-48 T 10-11-2016 IPR008628 Golgi phosphoprotein 3 GO:0048193|GO:0070273 A4G23_RS08470 fd6bc683c0236d2951c4f7f74f026fda 343 Gene3D G3DSA:2.30.30.60 149 195 6.8E-11 T 10-11-2016 A4G23_RS08470 fd6bc683c0236d2951c4f7f74f026fda 343 SUPERFAMILY SSF50182 134 193 4.9E-10 T 10-11-2016 IPR010920 LSM domain A4G23_RS08470 fd6bc683c0236d2951c4f7f74f026fda 343 SUPERFAMILY SSF82689 198 291 4.97E-10 T 10-11-2016 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 A4G23_RS08470 fd6bc683c0236d2951c4f7f74f026fda 343 SUPERFAMILY SSF82861 70 132 1.83E-9 T 10-11-2016 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 A4G23_RS08470 fd6bc683c0236d2951c4f7f74f026fda 343 Pfam PF00924 Mechanosensitive ion channel 92 291 4.7E-37 T 10-11-2016 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 A4G23_RS08470 fd6bc683c0236d2951c4f7f74f026fda 343 Gene3D G3DSA:3.30.70.100 205 289 2.5E-6 T 10-11-2016 A4G23_RS21170 b5a470af87fdc07bfa65354f3e5adb56 417 Pfam PF07730 Histidine kinase 194 265 1.6E-15 T 10-11-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4G23_RS21170 b5a470af87fdc07bfa65354f3e5adb56 417 Gene3D G3DSA:3.30.565.10 314 397 4.1E-5 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS21170 b5a470af87fdc07bfa65354f3e5adb56 417 SUPERFAMILY SSF55874 289 396 9.51E-14 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS21170 b5a470af87fdc07bfa65354f3e5adb56 417 SMART SM00387 308 398 1.6E-4 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS12430 4c93ab08f8f9326bd84176db691e0139 95 Gene3D G3DSA:2.60.40.10 19 83 1.9E-6 T 10-11-2016 IPR013783 Immunoglobulin-like fold A4G23_RS12430 4c93ab08f8f9326bd84176db691e0139 95 SUPERFAMILY SSF49452 17 92 2.55E-5 T 10-11-2016 IPR013784 Carbohydrate-binding-like fold GO:0030246 A4G23_RS12430 4c93ab08f8f9326bd84176db691e0139 95 Pfam PF07210 Protein of unknown function (DUF1416) 2 95 1.4E-35 T 10-11-2016 IPR010814 Protein of unknown function DUF1416 A4G23_RS00685 9fddfc3b15597496f41cadb08df37287 658 Gene3D G3DSA:3.40.50.880 392 595 3.9E-58 T 10-11-2016 IPR029062 Class I glutamine amidotransferase-like A4G23_RS00685 9fddfc3b15597496f41cadb08df37287 658 Pfam PF08532 Beta-galactosidase trimerisation domain 395 592 1.0E-52 T 10-11-2016 IPR013738 Beta-galactosidase trimerisation GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 A4G23_RS00685 9fddfc3b15597496f41cadb08df37287 658 PIRSF PIRSF001084 5 656 9.5E-243 T 10-11-2016 IPR003476 Glycoside hydrolase, family 42 GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 A4G23_RS00685 9fddfc3b15597496f41cadb08df37287 658 Gene3D G3DSA:2.60.40.1180 600 655 7.1E-6 T 10-11-2016 IPR013780 Glycosyl hydrolase, all-beta A4G23_RS00685 9fddfc3b15597496f41cadb08df37287 658 SUPERFAMILY SSF52317 392 592 4.73E-46 T 10-11-2016 IPR029062 Class I glutamine amidotransferase-like A4G23_RS00685 9fddfc3b15597496f41cadb08df37287 658 Gene3D G3DSA:3.20.20.80 14 385 3.2E-133 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS00685 9fddfc3b15597496f41cadb08df37287 658 SUPERFAMILY SSF51445 9 365 4.49E-115 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS00685 9fddfc3b15597496f41cadb08df37287 658 Pfam PF08533 Beta-galactosidase C-terminal domain 602 655 3.1E-10 T 10-11-2016 IPR013739 Beta-galactosidase C-terminal GO:0004565|GO:0006012 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 A4G23_RS00685 9fddfc3b15597496f41cadb08df37287 658 Pfam PF02449 Beta-galactosidase 17 383 8.1E-143 T 10-11-2016 IPR013529 Glycoside hydrolase, family 42, N-terminal GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 A4G23_RS20975 23b955fb5cff9a573b3cbb09773647ec 99 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 9 96 1.6E-18 T 10-11-2016 IPR010310 Type VII secretion system ESAT-6-like A4G23_RS20975 23b955fb5cff9a573b3cbb09773647ec 99 Gene3D G3DSA:1.10.287.1060 8 98 1.1E-22 T 10-11-2016 A4G23_RS20975 23b955fb5cff9a573b3cbb09773647ec 99 SUPERFAMILY SSF140453 7 98 9.55E-20 T 10-11-2016 IPR010310 Type VII secretion system ESAT-6-like A4G23_RS20975 23b955fb5cff9a573b3cbb09773647ec 99 Pfam PF06013 Proteins of 100 residues with WXG 10 91 2.6E-16 T 10-11-2016 IPR010310 Type VII secretion system ESAT-6-like A4G23_RS11190 439dbbe864958a6b09e1aa9ca7c90591 289 Gene3D G3DSA:3.40.50.1820 13 271 3.0E-19 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS11190 439dbbe864958a6b09e1aa9ca7c90591 289 Pfam PF12697 Alpha/beta hydrolase family 33 248 2.0E-10 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS11190 439dbbe864958a6b09e1aa9ca7c90591 289 SUPERFAMILY SSF53474 2 273 2.38E-26 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS25595 e4c4d703f2e912f0d6c1febeab4197fd 310 Pfam PF12710 haloacid dehalogenase-like hydrolase 41 248 8.0E-17 T 10-11-2016 A4G23_RS25595 e4c4d703f2e912f0d6c1febeab4197fd 310 Gene3D G3DSA:3.40.50.1000 143 269 2.1E-7 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS25595 e4c4d703f2e912f0d6c1febeab4197fd 310 Gene3D G3DSA:3.40.50.1000 39 56 2.1E-7 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS25595 e4c4d703f2e912f0d6c1febeab4197fd 310 SUPERFAMILY SSF56784 39 257 1.58E-17 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS07090 d9dcec71873fb53a3d70668005183058 332 Pfam PF13411 MerR HTH family regulatory protein 1 68 1.6E-15 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS07090 d9dcec71873fb53a3d70668005183058 332 SMART SM00422 1 70 7.9E-21 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS07090 d9dcec71873fb53a3d70668005183058 332 SUPERFAMILY SSF46955 1 107 1.47E-23 T 10-11-2016 IPR009061 Putative DNA-binding domain A4G23_RS07090 d9dcec71873fb53a3d70668005183058 332 Gene3D G3DSA:1.10.1660.10 1 113 8.9E-28 T 10-11-2016 A4G23_RS07090 d9dcec71873fb53a3d70668005183058 332 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 2.4E-5 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS07090 d9dcec71873fb53a3d70668005183058 332 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 2.4E-5 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS07090 d9dcec71873fb53a3d70668005183058 332 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 2.4E-5 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS22315 5f933cbfe456eac7af93b134567de592 355 Pfam PF00348 Polyprenyl synthetase 45 302 5.1E-56 T 10-11-2016 IPR000092 Polyprenyl synthetase GO:0008299 A4G23_RS22315 5f933cbfe456eac7af93b134567de592 355 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 93 107 - T 10-11-2016 IPR000092 Polyprenyl synthetase GO:0008299 A4G23_RS22315 5f933cbfe456eac7af93b134567de592 355 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 233 245 - T 10-11-2016 IPR000092 Polyprenyl synthetase GO:0008299 A4G23_RS22315 5f933cbfe456eac7af93b134567de592 355 Gene3D G3DSA:1.10.600.10 20 354 2.3E-84 T 10-11-2016 IPR008949 Isoprenoid synthase domain A4G23_RS22315 5f933cbfe456eac7af93b134567de592 355 SUPERFAMILY SSF48576 27 354 1.76E-74 T 10-11-2016 IPR008949 Isoprenoid synthase domain A4G23_RS22280 7e4e2402ffb7b9e3accddf80af53039a 111 Gene3D G3DSA:1.25.40.20 5 102 2.8E-7 T 10-11-2016 IPR020683 Ankyrin repeat-containing domain A4G23_RS22280 7e4e2402ffb7b9e3accddf80af53039a 111 SUPERFAMILY SSF48403 5 102 1.8E-5 T 10-11-2016 IPR020683 Ankyrin repeat-containing domain A4G23_RS20530 658052f423b07be3977beffb988bf9f4 354 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 202 221 7.4E-20 T 10-11-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A4G23_RS20530 658052f423b07be3977beffb988bf9f4 354 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 70 86 7.4E-20 T 10-11-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A4G23_RS20530 658052f423b07be3977beffb988bf9f4 354 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 154 166 7.4E-20 T 10-11-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A4G23_RS20530 658052f423b07be3977beffb988bf9f4 354 Gene3D G3DSA:2.10.109.10 67 116 1.4E-37 T 10-11-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain A4G23_RS20530 658052f423b07be3977beffb988bf9f4 354 Gene3D G3DSA:2.10.109.10 148 164 1.4E-37 T 10-11-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain A4G23_RS20530 658052f423b07be3977beffb988bf9f4 354 Gene3D G3DSA:2.10.109.10 202 254 1.4E-37 T 10-11-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain A4G23_RS20530 658052f423b07be3977beffb988bf9f4 354 SUPERFAMILY SSF51306 149 254 1.05E-46 T 10-11-2016 IPR015927 Peptidase S24/S26A/S26B/S26C A4G23_RS20530 658052f423b07be3977beffb988bf9f4 354 SUPERFAMILY SSF51306 69 117 1.05E-46 T 10-11-2016 IPR015927 Peptidase S24/S26A/S26B/S26C A4G23_RS20530 658052f423b07be3977beffb988bf9f4 354 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 56 248 1.4E-38 T 10-11-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A4G23_RS20530 658052f423b07be3977beffb988bf9f4 354 Pfam PF10502 Signal peptidase, peptidase S26 133 241 2.1E-8 T 10-11-2016 IPR019533 Peptidase S26 A4G23_RS20530 658052f423b07be3977beffb988bf9f4 354 Pfam PF00717 Peptidase S24-like 77 119 4.3E-11 T 10-11-2016 IPR019759 Peptidase S24/S26A/S26B A4G23_RS20530 658052f423b07be3977beffb988bf9f4 354 ProSitePatterns PS00761 Signal peptidases I signature 3. 207 220 - T 10-11-2016 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 A4G23_RS22520 526260a5e4a8ff7629d299da5f79fbde 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 3.0E-10 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS22520 526260a5e4a8ff7629d299da5f79fbde 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 3.0E-10 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS22520 526260a5e4a8ff7629d299da5f79fbde 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 3.0E-10 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS22520 526260a5e4a8ff7629d299da5f79fbde 221 Pfam PF00072 Response regulator receiver domain 4 102 5.8E-14 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS22520 526260a5e4a8ff7629d299da5f79fbde 221 SUPERFAMILY SSF52172 2 164 5.97E-17 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS22520 526260a5e4a8ff7629d299da5f79fbde 221 SMART SM00421 152 213 1.0E-11 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS22520 526260a5e4a8ff7629d299da5f79fbde 221 Gene3D G3DSA:1.10.10.10 153 213 6.6E-22 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS22520 526260a5e4a8ff7629d299da5f79fbde 221 ProSitePatterns PS00622 LuxR-type HTH domain signature. 169 196 - T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS22520 526260a5e4a8ff7629d299da5f79fbde 221 SUPERFAMILY SSF46894 149 200 9.35E-13 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS22520 526260a5e4a8ff7629d299da5f79fbde 221 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 199 1.5E-13 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS22520 526260a5e4a8ff7629d299da5f79fbde 221 SMART SM00448 2 124 2.0E-6 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS22520 526260a5e4a8ff7629d299da5f79fbde 221 Gene3D G3DSA:3.40.50.2300 2 152 8.8E-26 T 10-11-2016 A4G23_RS12080 9471b3fcd772e5c2129127ac93867cca 191 Pfam PF02342 TerD domain 1 187 8.6E-85 T 10-11-2016 IPR003325 TerD domain GO:0006950 A4G23_RS12080 9471b3fcd772e5c2129127ac93867cca 191 Gene3D G3DSA:2.60.60.30 18 185 3.9E-73 T 10-11-2016 A4G23_RS22525 e736173d43683bfd6353f525089d61e2 280 Gene3D G3DSA:3.40.50.1820 3 270 2.8E-33 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS22525 e736173d43683bfd6353f525089d61e2 280 Pfam PF00561 alpha/beta hydrolase fold 22 128 9.9E-11 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS22525 e736173d43683bfd6353f525089d61e2 280 SUPERFAMILY SSF53474 3 270 4.05E-32 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS19720 ca7ef1110e1a3cb8df884507c8f22397 96 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 1 94 1.6E-17 T 10-11-2016 IPR002767 Thiamine-binding protein A4G23_RS19720 ca7ef1110e1a3cb8df884507c8f22397 96 Pfam PF01910 Thiamine-binding protein 3 91 5.0E-29 T 10-11-2016 IPR002767 Thiamine-binding protein A4G23_RS19720 ca7ef1110e1a3cb8df884507c8f22397 96 Gene3D G3DSA:3.30.70.930 1 91 1.8E-34 T 10-11-2016 IPR029756 MTH1187/YkoF-like A4G23_RS19720 ca7ef1110e1a3cb8df884507c8f22397 96 SUPERFAMILY SSF89957 1 95 1.44E-28 T 10-11-2016 IPR029756 MTH1187/YkoF-like A4G23_RS09845 e7814de6eccc8cd9209e68112945f86f 229 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 100 8.2E-20 T 10-11-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 A4G23_RS09845 e7814de6eccc8cd9209e68112945f86f 229 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 153 207 2.8E-21 T 10-11-2016 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal A4G23_RS09845 e7814de6eccc8cd9209e68112945f86f 229 SUPERFAMILY SSF69754 3 115 4.45E-23 T 10-11-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 A4G23_RS09845 e7814de6eccc8cd9209e68112945f86f 229 Gene3D G3DSA:3.30.160.100 2 101 1.2E-26 T 10-11-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 A4G23_RS09845 e7814de6eccc8cd9209e68112945f86f 229 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 2 104 3.3E-22 T 10-11-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 A4G23_RS09530 226651978f0911f1e14f54c593761a60 506 SUPERFAMILY SSF48452 417 485 4.93E-14 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS09530 226651978f0911f1e14f54c593761a60 506 SUPERFAMILY SSF48452 218 378 4.93E-14 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS09530 226651978f0911f1e14f54c593761a60 506 SUPERFAMILY SSF48452 118 262 5.84E-8 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS09530 226651978f0911f1e14f54c593761a60 506 Gene3D G3DSA:1.25.40.10 386 485 2.1E-8 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS09530 226651978f0911f1e14f54c593761a60 506 SMART SM00028 309 342 190.0 T 10-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 A4G23_RS09530 226651978f0911f1e14f54c593761a60 506 SMART SM00028 448 481 1.0 T 10-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 A4G23_RS09530 226651978f0911f1e14f54c593761a60 506 SMART SM00028 275 308 98.0 T 10-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 A4G23_RS09530 226651978f0911f1e14f54c593761a60 506 Gene3D G3DSA:1.25.40.10 107 368 2.9E-21 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS12090 a6bc133fc307e403386a17628a7e6ef2 463 Gene3D G3DSA:1.10.390.10 330 460 4.6E-22 T 10-11-2016 A4G23_RS12090 a6bc133fc307e403386a17628a7e6ef2 463 Pfam PF01433 Peptidase family M1 55 285 8.9E-21 T 10-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4G23_RS12090 a6bc133fc307e403386a17628a7e6ef2 463 Pfam PF01433 Peptidase family M1 316 358 1.2E-15 T 10-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4G23_RS12090 a6bc133fc307e403386a17628a7e6ef2 463 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 316 331 5.7E-12 T 10-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4G23_RS12090 a6bc133fc307e403386a17628a7e6ef2 463 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 169 184 5.7E-12 T 10-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4G23_RS12090 a6bc133fc307e403386a17628a7e6ef2 463 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 216 231 5.7E-12 T 10-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4G23_RS12090 a6bc133fc307e403386a17628a7e6ef2 463 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 335 347 5.7E-12 T 10-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A4G23_RS12090 a6bc133fc307e403386a17628a7e6ef2 463 SUPERFAMILY SSF63737 39 232 6.41E-38 T 10-11-2016 A4G23_RS12090 a6bc133fc307e403386a17628a7e6ef2 463 SUPERFAMILY SSF55486 243 460 1.47E-49 T 10-11-2016 A4G23_RS03365 a1d63714617a36b24146cfe3ce5ffe52 456 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 14 218 38.645 T 10-11-2016 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4G23_RS03365 a1d63714617a36b24146cfe3ce5ffe52 456 SUPERFAMILY SSF142695 249 418 1.09E-65 T 10-11-2016 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 A4G23_RS03365 a1d63714617a36b24146cfe3ce5ffe52 456 Hamap MF_01283 Riboflavin biosynthesis protein RibBA [ribBA]. 15 439 49.994 T 10-11-2016 IPR016299 Riboflavin biosynthesis protein RibBA GO:0009231 KEGG: 00740+3.5.4.25+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7539 A4G23_RS03365 a1d63714617a36b24146cfe3ce5ffe52 456 Pfam PF00925 GTP cyclohydrolase II 251 415 1.7E-69 T 10-11-2016 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 A4G23_RS03365 a1d63714617a36b24146cfe3ce5ffe52 456 Gene3D G3DSA:3.90.870.10 14 218 3.0E-93 T 10-11-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain A4G23_RS03365 a1d63714617a36b24146cfe3ce5ffe52 456 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 20 213 5.6E-83 T 10-11-2016 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4G23_RS03365 a1d63714617a36b24146cfe3ce5ffe52 456 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 247 443 40.308 T 10-11-2016 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 A4G23_RS03365 a1d63714617a36b24146cfe3ce5ffe52 456 SUPERFAMILY SSF55821 13 216 6.87E-81 T 10-11-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain A4G23_RS03365 a1d63714617a36b24146cfe3ce5ffe52 456 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 17 214 2.4E-73 T 10-11-2016 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4G23_RS03365 a1d63714617a36b24146cfe3ce5ffe52 456 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 252 440 3.3E-71 T 10-11-2016 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 A4G23_RS22335 fbacfc6f9d4c8b4d8b68a3fe8a7afc8b 496 SUPERFAMILY SSF52540 104 280 5.38E-11 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS22335 fbacfc6f9d4c8b4d8b68a3fe8a7afc8b 496 Gene3D G3DSA:3.40.50.300 106 250 3.7E-6 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS22335 fbacfc6f9d4c8b4d8b68a3fe8a7afc8b 496 Pfam PF05729 NACHT domain 131 279 1.7E-10 T 10-11-2016 A4G23_RS22515 0323112f196c821896934b9dd2ee2b0e 425 Gene3D G3DSA:3.30.565.10 343 423 2.4E-7 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS22515 0323112f196c821896934b9dd2ee2b0e 425 SUPERFAMILY SSF55874 316 422 2.6E-15 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS22515 0323112f196c821896934b9dd2ee2b0e 425 Pfam PF07730 Histidine kinase 235 302 2.2E-14 T 10-11-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4G23_RS22515 0323112f196c821896934b9dd2ee2b0e 425 SMART SM00387 335 425 7.7E-6 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS22515 0323112f196c821896934b9dd2ee2b0e 425 Pfam PF13796 Putative sensor 28 207 6.0E-27 T 10-11-2016 IPR025828 Putative sensor domain A4G23_RS11745 93011ace62fef479ceb408c6ccfd608a 357 Pfam PF01418 Helix-turn-helix domain, rpiR family 69 140 1.1E-13 T 10-11-2016 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 A4G23_RS11745 93011ace62fef479ceb408c6ccfd608a 357 Gene3D G3DSA:1.10.10.10 67 141 3.4E-22 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS11745 93011ace62fef479ceb408c6ccfd608a 357 Gene3D G3DSA:3.40.50.10490 171 329 3.2E-41 T 10-11-2016 A4G23_RS11745 93011ace62fef479ceb408c6ccfd608a 357 SUPERFAMILY SSF46689 68 139 5.73E-15 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS11745 93011ace62fef479ceb408c6ccfd608a 357 SUPERFAMILY SSF53697 161 328 1.27E-39 T 10-11-2016 A4G23_RS11745 93011ace62fef479ceb408c6ccfd608a 357 Pfam PF01380 SIS domain 194 323 3.0E-24 T 10-11-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 A4G23_RS13025 a41c3b41214fb89102f521d2906a5015 323 Gene3D G3DSA:1.10.260.40 11 58 4.3E-6 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS13025 a41c3b41214fb89102f521d2906a5015 323 Pfam PF13560 Helix-turn-helix domain 11 64 4.2E-7 T 10-11-2016 A4G23_RS13025 a41c3b41214fb89102f521d2906a5015 323 Gene3D G3DSA:1.25.40.10 143 304 3.3E-6 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS13025 a41c3b41214fb89102f521d2906a5015 323 SUPERFAMILY SSF47413 10 59 1.24E-6 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS13025 a41c3b41214fb89102f521d2906a5015 323 SUPERFAMILY SSF48452 143 294 1.52E-5 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS13025 a41c3b41214fb89102f521d2906a5015 323 SMART SM00530 8 63 0.0062 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS02835 d634c001f2d9e37102fc0f100c250fb9 142 SUPERFAMILY SSF54909 13 102 1.25E-8 T 10-11-2016 IPR011008 Dimeric alpha-beta barrel A4G23_RS02835 d634c001f2d9e37102fc0f100c250fb9 142 Gene3D G3DSA:3.30.70.900 42 101 8.7E-4 T 10-11-2016 A4G23_RS02835 d634c001f2d9e37102fc0f100c250fb9 142 Pfam PF11695 Domain of unknown function (DUF3291) 58 127 1.4E-6 T 10-11-2016 IPR021708 Domain of unknown function DUF3291 A4G23_RS24450 f56689394a10338e3539e1b7d2b0e4d1 232 PIRSF PIRSF036625 14 228 3.4E-35 T 10-11-2016 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative A4G23_RS24450 f56689394a10338e3539e1b7d2b0e4d1 232 Gene3D G3DSA:1.10.10.10 168 223 3.4E-15 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS24450 f56689394a10338e3539e1b7d2b0e4d1 232 SMART SM01012 165 220 3.4E-20 T 10-11-2016 IPR005561 ANTAR domain GO:0003723 A4G23_RS24450 f56689394a10338e3539e1b7d2b0e4d1 232 SUPERFAMILY SSF52172 90 220 1.89E-9 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS24450 f56689394a10338e3539e1b7d2b0e4d1 232 SUPERFAMILY SSF55781 18 160 1.92E-10 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS24450 f56689394a10338e3539e1b7d2b0e4d1 232 Pfam PF03861 ANTAR domain 168 220 4.8E-17 T 10-11-2016 IPR005561 ANTAR domain GO:0003723 A4G23_RS07765 ecabd0546b9bc065d0c2a9f876889977 107 SUPERFAMILY SSF50022 10 105 2.1E-30 T 10-11-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A4G23_RS07765 ecabd0546b9bc065d0c2a9f876889977 107 Gene3D G3DSA:2.102.10.10 9 106 8.9E-35 T 10-11-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A4G23_RS07765 ecabd0546b9bc065d0c2a9f876889977 107 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 11 106 6.1E-28 T 10-11-2016 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 A4G23_RS07765 ecabd0546b9bc065d0c2a9f876889977 107 Pfam PF13806 Rieske-like [2Fe-2S] domain 11 106 1.9E-33 T 10-11-2016 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 A4G23_RS24790 c68229a1d303b13ebb3c5790067598e6 453 Gene3D G3DSA:3.40.630.10 71 344 1.3E-35 T 10-11-2016 A4G23_RS24790 c68229a1d303b13ebb3c5790067598e6 453 SUPERFAMILY SSF53187 65 273 2.28E-40 T 10-11-2016 A4G23_RS24790 c68229a1d303b13ebb3c5790067598e6 453 SMART SM00631 65 285 1.9E-5 T 10-11-2016 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 A4G23_RS24790 c68229a1d303b13ebb3c5790067598e6 453 Pfam PF00246 Zinc carboxypeptidase 73 187 3.0E-20 T 10-11-2016 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 A4G23_RS01840 48aba153389b6a713374dcb5c494133e 410 SUPERFAMILY SSF103473 26 407 3.53E-37 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS01840 48aba153389b6a713374dcb5c494133e 410 Pfam PF07690 Major Facilitator Superfamily 239 405 3.4E-8 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS01840 48aba153389b6a713374dcb5c494133e 410 Pfam PF07690 Major Facilitator Superfamily 37 226 3.8E-11 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS01840 48aba153389b6a713374dcb5c494133e 410 Gene3D G3DSA:1.20.1250.20 229 402 1.1E-16 T 10-11-2016 A4G23_RS01840 48aba153389b6a713374dcb5c494133e 410 Gene3D G3DSA:1.20.1250.20 31 197 1.2E-12 T 10-11-2016 A4G23_RS17040 6907044c8ac573510243f137e496753f 562 Pfam PF14431 YwqJ-like deaminase 425 554 1.6E-15 T 10-11-2016 IPR025968 YwqJ-like deaminase A4G23_RS24360 19f8025edb9830c283533f2b0aeb523c 462 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 99 108 - T 10-11-2016 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 A4G23_RS24360 19f8025edb9830c283533f2b0aeb523c 462 SUPERFAMILY SSF55031 311 349 1.28E-8 T 10-11-2016 IPR011650 Peptidase M20, dimerisation domain A4G23_RS24360 19f8025edb9830c283533f2b0aeb523c 462 SUPERFAMILY SSF55031 220 262 1.28E-8 T 10-11-2016 IPR011650 Peptidase M20, dimerisation domain A4G23_RS24360 19f8025edb9830c283533f2b0aeb523c 462 Pfam PF01546 Peptidase family M20/M25/M40 100 460 1.6E-35 T 10-11-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A4G23_RS24360 19f8025edb9830c283533f2b0aeb523c 462 Pfam PF07687 Peptidase dimerisation domain 218 348 1.9E-12 T 10-11-2016 IPR011650 Peptidase M20, dimerisation domain A4G23_RS24360 19f8025edb9830c283533f2b0aeb523c 462 SUPERFAMILY SSF53187 29 209 2.03E-52 T 10-11-2016 A4G23_RS24360 19f8025edb9830c283533f2b0aeb523c 462 SUPERFAMILY SSF53187 372 459 2.03E-52 T 10-11-2016 A4G23_RS24360 19f8025edb9830c283533f2b0aeb523c 462 Gene3D G3DSA:3.30.70.360 230 269 1.1E-20 T 10-11-2016 IPR011650 Peptidase M20, dimerisation domain A4G23_RS24360 19f8025edb9830c283533f2b0aeb523c 462 Gene3D G3DSA:3.30.70.360 312 355 1.1E-20 T 10-11-2016 IPR011650 Peptidase M20, dimerisation domain A4G23_RS24360 19f8025edb9830c283533f2b0aeb523c 462 Gene3D G3DSA:3.40.630.10 30 229 1.4E-55 T 10-11-2016 A4G23_RS24360 19f8025edb9830c283533f2b0aeb523c 462 Gene3D G3DSA:3.40.630.10 397 460 1.4E-55 T 10-11-2016 A4G23_RS14530 4f63c4ced95900528060b7c78e400b0b 303 SUPERFAMILY SSF55486 158 278 8.38E-10 T 10-11-2016 A4G23_RS14530 4f63c4ced95900528060b7c78e400b0b 303 Pfam PF11350 Protein of unknown function (DUF3152) 114 280 1.5E-35 T 10-11-2016 IPR022603 Domain of unknown function DUF3152 A4G23_RS10460 c46b27074d400a5de264c088479ee87e 278 Gene3D G3DSA:2.60.40.1240 156 277 2.2E-13 T 10-11-2016 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain A4G23_RS10460 c46b27074d400a5de264c088479ee87e 278 Pfam PF11611 Domain of unknown function (DUF4352) 162 267 2.5E-10 T 10-11-2016 IPR029051 Domain of unknown function DUF4352 A4G23_RS00490 f6f3d3414f9909ce92318642d8d0986f 133 ProSitePatterns PS00669 Gas vesicles protein GVPa signature 2. 52 65 - T 10-11-2016 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 A4G23_RS00490 f6f3d3414f9909ce92318642d8d0986f 133 Hamap MF_00576 Gas vesicle structural protein [gvpA]. 7 93 27.3 T 10-11-2016 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 A4G23_RS00490 f6f3d3414f9909ce92318642d8d0986f 133 Pfam PF00741 Gas vesicle protein 19 56 2.6E-12 T 10-11-2016 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 A4G23_RS00490 f6f3d3414f9909ce92318642d8d0986f 133 ProSitePatterns PS00234 Gas vesicles protein GVPa signature 1. 19 33 - T 10-11-2016 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 A4G23_RS16100 d525afbacf8affa3ae7921df65bfa35a 646 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 3 640 7.8E-233 T 10-11-2016 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16100 d525afbacf8affa3ae7921df65bfa35a 646 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 66 123 3.2E-24 T 10-11-2016 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16100 d525afbacf8affa3ae7921df65bfa35a 646 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 86 106 2.5E-9 T 10-11-2016 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 A4G23_RS16100 d525afbacf8affa3ae7921df65bfa35a 646 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 264 286 2.5E-9 T 10-11-2016 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 A4G23_RS16100 d525afbacf8affa3ae7921df65bfa35a 646 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 420 442 2.5E-9 T 10-11-2016 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 A4G23_RS16100 d525afbacf8affa3ae7921df65bfa35a 646 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 60 84 2.5E-9 T 10-11-2016 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 A4G23_RS16100 d525afbacf8affa3ae7921df65bfa35a 646 Pfam PF00361 Proton-conducting membrane transporter 135 418 1.0E-81 T 10-11-2016 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16100 d525afbacf8affa3ae7921df65bfa35a 646 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 159 180 1.4E-59 T 10-11-2016 A4G23_RS16100 d525afbacf8affa3ae7921df65bfa35a 646 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 421 440 1.4E-59 T 10-11-2016 A4G23_RS16100 d525afbacf8affa3ae7921df65bfa35a 646 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 224 245 1.4E-59 T 10-11-2016 A4G23_RS16100 d525afbacf8affa3ae7921df65bfa35a 646 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 84 109 1.4E-59 T 10-11-2016 A4G23_RS16100 d525afbacf8affa3ae7921df65bfa35a 646 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 112 132 1.4E-59 T 10-11-2016 A4G23_RS16100 d525afbacf8affa3ae7921df65bfa35a 646 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 246 272 1.4E-59 T 10-11-2016 A4G23_RS16100 d525afbacf8affa3ae7921df65bfa35a 646 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 314 326 1.4E-59 T 10-11-2016 A4G23_RS14360 4663835a54389f71dbf8f30abc67d20c 311 Pfam PF08223 PaaX-like protein C-terminal domain 106 273 1.7E-25 T 10-11-2016 IPR013225 PaaX-like, C-terminal A4G23_RS14360 4663835a54389f71dbf8f30abc67d20c 311 Pfam PF07848 PaaX-like protein 26 76 4.4E-5 T 10-11-2016 IPR012906 PaaX-like, N-terminal A4G23_RS14360 4663835a54389f71dbf8f30abc67d20c 311 PIRSF PIRSF020623 8 279 9.5E-32 T 10-11-2016 IPR011965 Phenylacetic acid degradation operon negative regulatory protein PaaX GO:0006351 A4G23_RS14010 b78e3711089c4ac798d8a3dab9c3745c 247 TIGRFAM TIGR00715 precor6x_red: precorrin-6x reductase 1 242 1.8E-43 T 10-11-2016 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 A4G23_RS14010 b78e3711089c4ac798d8a3dab9c3745c 247 Pfam PF02571 Precorrin-6x reductase CbiJ/CobK 2 240 4.7E-72 T 10-11-2016 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 A4G23_RS14010 b78e3711089c4ac798d8a3dab9c3745c 247 Gene3D G3DSA:3.40.50.2300 182 237 3.7E-4 T 10-11-2016 A4G23_RS11685 bc7f5369738ef0094a65526e99aa6030 205 SUPERFAMILY SSF160631 3 129 2.09E-6 T 10-11-2016 A4G23_RS11685 bc7f5369738ef0094a65526e99aa6030 205 Pfam PF11774 Lsr2 169 200 2.4E-7 T 10-11-2016 IPR024412 Lsr2 A4G23_RS07835 299515fec9ee12db03be957b5fa9cd09 455 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 171 3.4E-8 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS07835 299515fec9ee12db03be957b5fa9cd09 455 PIRSF PIRSF000362 1 453 2.1E-164 T 10-11-2016 IPR021163 Ferredoxin-NADP+ reductase, adrenodoxin-type GO:0016491|GO:0055114 Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 A4G23_RS07835 299515fec9ee12db03be957b5fa9cd09 455 SUPERFAMILY SSF51971 4 215 2.47E-57 T 10-11-2016 A4G23_RS07835 299515fec9ee12db03be957b5fa9cd09 455 SUPERFAMILY SSF51971 264 321 2.47E-57 T 10-11-2016 A4G23_RS07835 299515fec9ee12db03be957b5fa9cd09 455 Gene3D G3DSA:3.40.50.720 4 99 6.6E-75 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS07835 299515fec9ee12db03be957b5fa9cd09 455 Gene3D G3DSA:3.40.50.720 321 449 6.6E-75 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS07835 299515fec9ee12db03be957b5fa9cd09 455 Gene3D G3DSA:3.50.50.60 100 320 2.5E-67 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS07835 299515fec9ee12db03be957b5fa9cd09 455 PRINTS PR00419 Adrenodoxin reductase family signature 6 28 4.7E-13 T 10-11-2016 A4G23_RS07835 299515fec9ee12db03be957b5fa9cd09 455 PRINTS PR00419 Adrenodoxin reductase family signature 149 163 4.7E-13 T 10-11-2016 A4G23_RS00155 aaf9c128357839fb2d5c9081dd00e72a 285 SUPERFAMILY SSF53474 3 273 7.6E-39 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS00155 aaf9c128357839fb2d5c9081dd00e72a 285 Gene3D G3DSA:3.40.50.1820 5 273 1.6E-37 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS11640 64ba27c003428f10b85604111e4af244 327 Gene3D G3DSA:3.40.190.10 24 116 6.6E-10 T 10-11-2016 A4G23_RS11640 64ba27c003428f10b85604111e4af244 327 Gene3D G3DSA:3.40.190.10 220 239 6.6E-10 T 10-11-2016 A4G23_RS11640 64ba27c003428f10b85604111e4af244 327 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 49 62 - T 10-11-2016 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 A4G23_RS11640 64ba27c003428f10b85604111e4af244 327 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 38 236 1.5E-25 T 10-11-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A4G23_RS11640 64ba27c003428f10b85604111e4af244 327 SMART SM00062 26 249 2.1E-34 T 10-11-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A4G23_RS11640 64ba27c003428f10b85604111e4af244 327 SUPERFAMILY SSF53850 17 245 1.55E-42 T 10-11-2016 A4G23_RS11640 64ba27c003428f10b85604111e4af244 327 Gene3D G3DSA:3.40.190.10 117 219 1.4E-14 T 10-11-2016 A4G23_RS03200 5c56d9f74b714629f1ee47be4d46c9cb 426 Pfam PF07690 Major Facilitator Superfamily 39 383 1.2E-43 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS03200 5c56d9f74b714629f1ee47be4d46c9cb 426 SUPERFAMILY SSF103473 15 424 7.59E-79 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS03200 5c56d9f74b714629f1ee47be4d46c9cb 426 Gene3D G3DSA:1.20.1250.20 240 424 3.8E-23 T 10-11-2016 A4G23_RS03200 5c56d9f74b714629f1ee47be4d46c9cb 426 ProSitePatterns PS00217 Sugar transport proteins signature 2. 130 155 - T 10-11-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A4G23_RS03200 5c56d9f74b714629f1ee47be4d46c9cb 426 Gene3D G3DSA:1.20.1250.20 32 212 1.3E-32 T 10-11-2016 A4G23_RS01505 46c5ef2a44e91fefe7e89eb71b2fde62 147 SUPERFAMILY SSF46785 2 132 4.2E-25 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS01505 46c5ef2a44e91fefe7e89eb71b2fde62 147 Pfam PF02082 Transcriptional regulator 2 81 9.6E-15 T 10-11-2016 IPR000944 Transcription regulator Rrf2-type A4G23_RS01505 46c5ef2a44e91fefe7e89eb71b2fde62 147 Gene3D G3DSA:1.10.10.10 2 131 1.1E-27 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS01505 46c5ef2a44e91fefe7e89eb71b2fde62 147 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 2 130 3.0E-23 T 10-11-2016 IPR000944 Transcription regulator Rrf2-type A4G23_RS08685 22dfc630c248ee80eb2cf7e5d15c21fe 314 Pfam PF04542 Sigma-70 region 2 15 73 2.3E-13 T 10-11-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS08685 22dfc630c248ee80eb2cf7e5d15c21fe 314 Pfam PF08281 Sigma-70, region 4 111 161 2.2E-13 T 10-11-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS08685 22dfc630c248ee80eb2cf7e5d15c21fe 314 Gene3D G3DSA:1.10.1740.10 12 76 2.5E-12 T 10-11-2016 A4G23_RS08685 22dfc630c248ee80eb2cf7e5d15c21fe 314 Gene3D G3DSA:1.10.10.10 111 163 3.6E-13 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS08685 22dfc630c248ee80eb2cf7e5d15c21fe 314 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 14 162 3.3E-14 T 10-11-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS08685 22dfc630c248ee80eb2cf7e5d15c21fe 314 SUPERFAMILY SSF88659 87 162 2.06E-11 T 10-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS08685 22dfc630c248ee80eb2cf7e5d15c21fe 314 SUPERFAMILY SSF54427 172 296 5.15E-11 T 10-11-2016 IPR032710 NTF2-like domain A4G23_RS08685 22dfc630c248ee80eb2cf7e5d15c21fe 314 SUPERFAMILY SSF88946 15 90 2.94E-12 T 10-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS08685 22dfc630c248ee80eb2cf7e5d15c21fe 314 Gene3D G3DSA:3.10.450.50 172 296 4.0E-11 T 10-11-2016 IPR032710 NTF2-like domain A4G23_RS14630 8784fe851d45d39c61e2b10604bf292b 421 SUPERFAMILY SSF51905 1 188 1.85E-35 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS14630 8784fe851d45d39c61e2b10604bf292b 421 SUPERFAMILY SSF51905 317 413 1.85E-35 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS14630 8784fe851d45d39c61e2b10604bf292b 421 Pfam PF13450 NAD(P)-binding Rossmann-like domain 5 35 4.1E-6 T 10-11-2016 A4G23_RS14630 8784fe851d45d39c61e2b10604bf292b 421 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 167 182 3.6E-20 T 10-11-2016 A4G23_RS14630 8784fe851d45d39c61e2b10604bf292b 421 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 330 345 3.6E-20 T 10-11-2016 A4G23_RS14630 8784fe851d45d39c61e2b10604bf292b 421 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 3.6E-20 T 10-11-2016 A4G23_RS14630 8784fe851d45d39c61e2b10604bf292b 421 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 345 361 3.6E-20 T 10-11-2016 A4G23_RS14630 8784fe851d45d39c61e2b10604bf292b 421 Pfam PF01494 FAD binding domain 320 370 1.3E-7 T 10-11-2016 IPR002938 FAD-binding domain GO:0071949 A4G23_RS14630 8784fe851d45d39c61e2b10604bf292b 421 Gene3D G3DSA:3.50.50.60 1 194 3.2E-27 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS14630 8784fe851d45d39c61e2b10604bf292b 421 Gene3D G3DSA:3.50.50.60 318 399 3.2E-27 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS22330 60d678cf1c31ae6ab4db6efe1277e166 452 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 394 403 - T 10-11-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A4G23_RS22330 60d678cf1c31ae6ab4db6efe1277e166 452 Pfam PF00067 Cytochrome P450 18 440 3.7E-75 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS22330 60d678cf1c31ae6ab4db6efe1277e166 452 PRINTS PR00385 P450 superfamily signature 401 412 4.7E-12 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS22330 60d678cf1c31ae6ab4db6efe1277e166 452 PRINTS PR00385 P450 superfamily signature 317 328 4.7E-12 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS22330 60d678cf1c31ae6ab4db6efe1277e166 452 PRINTS PR00385 P450 superfamily signature 392 401 4.7E-12 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS22330 60d678cf1c31ae6ab4db6efe1277e166 452 PRINTS PR00385 P450 superfamily signature 265 282 4.7E-12 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS22330 60d678cf1c31ae6ab4db6efe1277e166 452 Gene3D G3DSA:1.10.630.10 18 452 8.2E-114 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS22330 60d678cf1c31ae6ab4db6efe1277e166 452 PRINTS PR00463 E-class P450 group I signature 41 60 7.2E-23 T 10-11-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS22330 60d678cf1c31ae6ab4db6efe1277e166 452 PRINTS PR00463 E-class P450 group I signature 254 271 7.2E-23 T 10-11-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS22330 60d678cf1c31ae6ab4db6efe1277e166 452 PRINTS PR00463 E-class P450 group I signature 391 401 7.2E-23 T 10-11-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS22330 60d678cf1c31ae6ab4db6efe1277e166 452 PRINTS PR00463 E-class P450 group I signature 356 380 7.2E-23 T 10-11-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS22330 60d678cf1c31ae6ab4db6efe1277e166 452 PRINTS PR00463 E-class P450 group I signature 274 300 7.2E-23 T 10-11-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS22330 60d678cf1c31ae6ab4db6efe1277e166 452 PRINTS PR00463 E-class P450 group I signature 401 424 7.2E-23 T 10-11-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS22330 60d678cf1c31ae6ab4db6efe1277e166 452 SUPERFAMILY SSF48264 17 452 1.11E-107 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS04190 0e3e7ec5e267ca627bf21f3b6324900c 298 SUPERFAMILY SSF46785 5 115 7.17E-26 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS04190 0e3e7ec5e267ca627bf21f3b6324900c 298 Gene3D G3DSA:1.10.10.10 7 91 3.2E-24 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS04190 0e3e7ec5e267ca627bf21f3b6324900c 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 2.6E-6 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS04190 0e3e7ec5e267ca627bf21f3b6324900c 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 2.6E-6 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS04190 0e3e7ec5e267ca627bf21f3b6324900c 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 2.6E-6 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS04190 0e3e7ec5e267ca627bf21f3b6324900c 298 Gene3D G3DSA:3.40.190.10 97 181 3.8E-16 T 10-11-2016 A4G23_RS04190 0e3e7ec5e267ca627bf21f3b6324900c 298 Gene3D G3DSA:3.40.190.10 182 268 2.4E-19 T 10-11-2016 A4G23_RS04190 0e3e7ec5e267ca627bf21f3b6324900c 298 Pfam PF03466 LysR substrate binding domain 94 297 4.6E-46 T 10-11-2016 IPR005119 LysR, substrate-binding A4G23_RS04190 0e3e7ec5e267ca627bf21f3b6324900c 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 66 3.6E-21 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS04190 0e3e7ec5e267ca627bf21f3b6324900c 298 SUPERFAMILY SSF53850 96 294 1.66E-40 T 10-11-2016 A4G23_RS01270 117f75d67f4f85376dd172ad68605f97 395 PRINTS PR00463 E-class P450 group I signature 216 242 4.9E-27 T 10-11-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS01270 117f75d67f4f85376dd172ad68605f97 395 PRINTS PR00463 E-class P450 group I signature 342 365 4.9E-27 T 10-11-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS01270 117f75d67f4f85376dd172ad68605f97 395 PRINTS PR00463 E-class P450 group I signature 196 213 4.9E-27 T 10-11-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS01270 117f75d67f4f85376dd172ad68605f97 395 PRINTS PR00463 E-class P450 group I signature 332 342 4.9E-27 T 10-11-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS01270 117f75d67f4f85376dd172ad68605f97 395 PRINTS PR00463 E-class P450 group I signature 297 321 4.9E-27 T 10-11-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS01270 117f75d67f4f85376dd172ad68605f97 395 SUPERFAMILY SSF48264 2 393 1.27E-97 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS01270 117f75d67f4f85376dd172ad68605f97 395 Gene3D G3DSA:1.10.630.10 2 394 3.6E-106 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS01270 117f75d67f4f85376dd172ad68605f97 395 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 335 344 - T 10-11-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A4G23_RS01270 117f75d67f4f85376dd172ad68605f97 395 Pfam PF00067 Cytochrome P450 2 375 2.4E-79 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS01270 117f75d67f4f85376dd172ad68605f97 395 PRINTS PR00385 P450 superfamily signature 342 353 1.1E-13 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS01270 117f75d67f4f85376dd172ad68605f97 395 PRINTS PR00385 P450 superfamily signature 259 270 1.1E-13 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS01270 117f75d67f4f85376dd172ad68605f97 395 PRINTS PR00385 P450 superfamily signature 333 342 1.1E-13 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS01270 117f75d67f4f85376dd172ad68605f97 395 PRINTS PR00385 P450 superfamily signature 207 224 1.1E-13 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS25385 8585631204683597ed829e559928125c 342 Gene3D G3DSA:1.10.1040.10 178 317 3.4E-27 T 10-11-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A4G23_RS25385 8585631204683597ed829e559928125c 342 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 181 316 2.7E-21 T 10-11-2016 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 A4G23_RS25385 8585631204683597ed829e559928125c 342 SUPERFAMILY SSF48179 178 317 1.9E-22 T 10-11-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A4G23_RS25385 8585631204683597ed829e559928125c 342 Pfam PF02558 Ketopantoate reductase PanE/ApbA 5 155 6.9E-33 T 10-11-2016 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 A4G23_RS25385 8585631204683597ed829e559928125c 342 Gene3D G3DSA:3.40.50.720 2 173 3.2E-34 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS25385 8585631204683597ed829e559928125c 342 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 4 318 1.2E-61 T 10-11-2016 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 A4G23_RS25385 8585631204683597ed829e559928125c 342 SUPERFAMILY SSF51735 4 125 8.54E-16 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS14090 e09f113d84b80b1296b6b362feed9dff 119 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 3 116 18.532 T 10-11-2016 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 A4G23_RS14090 e09f113d84b80b1296b6b362feed9dff 119 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 4 111 4.3E-23 T 10-11-2016 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 A4G23_RS06360 a55bd9aee1fa28a9211b787992d92d2b 383 SUPERFAMILY SSF51905 6 226 1.02E-44 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS06360 a55bd9aee1fa28a9211b787992d92d2b 383 SUPERFAMILY SSF51905 321 378 1.02E-44 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS06360 a55bd9aee1fa28a9211b787992d92d2b 383 Pfam PF01266 FAD dependent oxidoreductase 7 358 4.2E-64 T 10-11-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A4G23_RS06360 a55bd9aee1fa28a9211b787992d92d2b 383 Gene3D G3DSA:3.50.50.60 321 379 5.6E-44 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS06360 a55bd9aee1fa28a9211b787992d92d2b 383 Gene3D G3DSA:3.50.50.60 147 225 5.6E-44 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS06360 a55bd9aee1fa28a9211b787992d92d2b 383 Gene3D G3DSA:3.50.50.60 4 85 5.6E-44 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS06360 a55bd9aee1fa28a9211b787992d92d2b 383 SUPERFAMILY SSF54373 227 319 9.81E-22 T 10-11-2016 A4G23_RS06360 a55bd9aee1fa28a9211b787992d92d2b 383 TIGRFAM TIGR02352 thiamin_ThiO: glycine oxidase ThiO 8 363 5.0E-119 T 10-11-2016 IPR012727 Glycine oxidase ThiO GO:0016491|GO:0050660 A4G23_RS06360 a55bd9aee1fa28a9211b787992d92d2b 383 Gene3D G3DSA:3.30.9.10 95 146 2.2E-10 T 10-11-2016 A4G23_RS06360 a55bd9aee1fa28a9211b787992d92d2b 383 Gene3D G3DSA:3.30.9.10 226 317 2.2E-10 T 10-11-2016 A4G23_RS00400 933514f42f5a3e2362078bf57ed5ee99 359 SUPERFAMILY SSF51395 2 348 4.23E-119 T 10-11-2016 A4G23_RS00400 933514f42f5a3e2362078bf57ed5ee99 359 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 343 8.1E-74 T 10-11-2016 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 A4G23_RS00400 933514f42f5a3e2362078bf57ed5ee99 359 Gene3D G3DSA:3.20.20.70 2 348 2.9E-134 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS00285 9a9cb93567edf6fec7885bba2e5f90d6 67 PIRSF PIRSF002599 1 67 1.3E-25 T 10-11-2016 IPR012156 Cold shock, CspA GO:0003676 A4G23_RS00285 9a9cb93567edf6fec7885bba2e5f90d6 67 SMART SM00357 3 67 2.6E-30 T 10-11-2016 IPR011129 Cold shock protein GO:0003676 A4G23_RS00285 9a9cb93567edf6fec7885bba2e5f90d6 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 2.1E-30 T 10-11-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4G23_RS00285 9a9cb93567edf6fec7885bba2e5f90d6 67 PRINTS PR00050 Cold shock protein signature 25 34 3.5E-17 T 10-11-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4G23_RS00285 9a9cb93567edf6fec7885bba2e5f90d6 67 PRINTS PR00050 Cold shock protein signature 4 19 3.5E-17 T 10-11-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4G23_RS00285 9a9cb93567edf6fec7885bba2e5f90d6 67 PRINTS PR00050 Cold shock protein signature 40 58 3.5E-17 T 10-11-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4G23_RS00285 9a9cb93567edf6fec7885bba2e5f90d6 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 10-11-2016 IPR019844 Cold-shock conserved site A4G23_RS00285 9a9cb93567edf6fec7885bba2e5f90d6 67 Gene3D G3DSA:2.40.50.140 1 65 7.2E-30 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS00285 9a9cb93567edf6fec7885bba2e5f90d6 67 SUPERFAMILY SSF50249 1 66 2.23E-24 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS02075 578aa1e0b4da00b8a5cbc589fa36527b 675 Gene3D G3DSA:2.120.10.30 55 303 2.7E-13 T 10-11-2016 IPR011042 Six-bladed beta-propeller, TolB-like A4G23_RS02075 578aa1e0b4da00b8a5cbc589fa36527b 675 Gene3D G3DSA:2.120.10.30 341 428 6.7E-7 T 10-11-2016 IPR011042 Six-bladed beta-propeller, TolB-like A4G23_RS02075 578aa1e0b4da00b8a5cbc589fa36527b 675 Gene3D G3DSA:2.120.10.30 488 612 6.7E-7 T 10-11-2016 IPR011042 Six-bladed beta-propeller, TolB-like A4G23_RS02075 578aa1e0b4da00b8a5cbc589fa36527b 675 SUPERFAMILY SSF50998 332 412 4.32E-11 T 10-11-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily A4G23_RS02075 578aa1e0b4da00b8a5cbc589fa36527b 675 SUPERFAMILY SSF50998 470 635 4.32E-11 T 10-11-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily A4G23_RS02075 578aa1e0b4da00b8a5cbc589fa36527b 675 SUPERFAMILY SSF75011 53 302 1.57E-16 T 10-11-2016 A4G23_RS22235 4ca987fed0614f2c19488e3ab6fb1eaa 255 Gene3D G3DSA:3.40.50.1820 43 234 4.0E-20 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS22235 4ca987fed0614f2c19488e3ab6fb1eaa 255 SMART SM01110 35 241 4.2E-5 T 10-11-2016 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 A4G23_RS22235 4ca987fed0614f2c19488e3ab6fb1eaa 255 SUPERFAMILY SSF53474 28 233 1.66E-16 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS22235 4ca987fed0614f2c19488e3ab6fb1eaa 255 Pfam PF08237 PE-PPE domain 75 194 1.2E-13 T 10-11-2016 IPR013228 PE-PPE, C-terminal A4G23_RS19975 df53ce8910813f74e54bc5fb60b4242a 257 Pfam PF14581 SseB protein C-terminal domain 135 239 4.4E-18 T 10-11-2016 IPR027945 SseB protein, C-terminal A4G23_RS06545 d10d28c692340d07c288cae469194d10 269 Gene3D G3DSA:1.10.760.10 48 133 2.2E-18 T 10-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4G23_RS06545 d10d28c692340d07c288cae469194d10 269 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 142 216 4.0E-13 T 10-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4G23_RS06545 d10d28c692340d07c288cae469194d10 269 PIRSF PIRSF000007 1 263 1.9E-127 T 10-11-2016 IPR009152 Ubiquinol-cytochrome-c reductase, cytochrome c subunit GO:0005506|GO:0009055|GO:0016021|GO:0020037 A4G23_RS06545 d10d28c692340d07c288cae469194d10 269 Pfam PF00034 Cytochrome c 50 125 3.8E-9 T 10-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4G23_RS06545 d10d28c692340d07c288cae469194d10 269 SUPERFAMILY SSF46626 124 217 2.62E-27 T 10-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4G23_RS06545 d10d28c692340d07c288cae469194d10 269 SUPERFAMILY SSF46626 13 132 4.3E-19 T 10-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4G23_RS06545 d10d28c692340d07c288cae469194d10 269 Gene3D G3DSA:1.10.760.10 142 223 8.3E-21 T 10-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4G23_RS02230 012949323ec235f8303cbe8434c7ad4a 1004 SUPERFAMILY SSF48452 692 876 2.58E-7 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS02230 012949323ec235f8303cbe8434c7ad4a 1004 SUPERFAMILY SSF48452 606 752 2.81E-11 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS02230 012949323ec235f8303cbe8434c7ad4a 1004 Gene3D G3DSA:1.25.40.10 600 881 4.0E-13 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS12875 9559fe7f152fbf7d56aebfc986879523 359 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 11 356 39.93 T 10-11-2016 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A4G23_RS12875 9559fe7f152fbf7d56aebfc986879523 359 Pfam PF00586 AIR synthase related protein, N-terminal domain 67 170 7.9E-16 T 10-11-2016 IPR016188 PurM-like, N-terminal domain A4G23_RS12875 9559fe7f152fbf7d56aebfc986879523 359 Gene3D G3DSA:3.90.650.10 179 346 5.1E-62 T 10-11-2016 IPR010918 AIR synthase-related protein, C-terminal domain A4G23_RS12875 9559fe7f152fbf7d56aebfc986879523 359 SUPERFAMILY SSF55326 12 175 4.64E-45 T 10-11-2016 A4G23_RS12875 9559fe7f152fbf7d56aebfc986879523 359 Pfam PF02769 AIR synthase related protein, C-terminal domain 183 346 1.6E-30 T 10-11-2016 IPR010918 AIR synthase-related protein, C-terminal domain A4G23_RS12875 9559fe7f152fbf7d56aebfc986879523 359 Gene3D G3DSA:3.30.1330.10 27 175 1.5E-51 T 10-11-2016 IPR016188 PurM-like, N-terminal domain A4G23_RS12875 9559fe7f152fbf7d56aebfc986879523 359 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 12 343 9.9E-125 T 10-11-2016 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A4G23_RS12875 9559fe7f152fbf7d56aebfc986879523 359 SUPERFAMILY SSF56042 179 346 9.12E-52 T 10-11-2016 IPR010918 AIR synthase-related protein, C-terminal domain A4G23_RS24110 e7914c56929becffaa4fb9c109cc429b 467 Gene3D G3DSA:2.30.40.10 4 74 5.2E-28 T 10-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4G23_RS24110 e7914c56929becffaa4fb9c109cc429b 467 SUPERFAMILY SSF51338 363 462 1.34E-32 T 10-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4G23_RS24110 e7914c56929becffaa4fb9c109cc429b 467 SUPERFAMILY SSF51556 60 388 2.22E-104 T 10-11-2016 IPR032466 Metal-dependent hydrolase A4G23_RS24110 e7914c56929becffaa4fb9c109cc429b 467 SUPERFAMILY SSF51338 5 72 7.56E-13 T 10-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4G23_RS24110 e7914c56929becffaa4fb9c109cc429b 467 Gene3D G3DSA:3.20.20.140 75 382 4.5E-114 T 10-11-2016 A4G23_RS24110 e7914c56929becffaa4fb9c109cc429b 467 TIGRFAM TIGR02033 D-hydantoinase: dihydropyrimidinase 6 459 5.7E-167 T 10-11-2016 IPR011778 Hydantoinase/dihydropyrimidinase GO:0005737 Reactome: R-HSA-399956 A4G23_RS24110 e7914c56929becffaa4fb9c109cc429b 467 Pfam PF01979 Amidohydrolase family 56 442 4.1E-24 T 10-11-2016 IPR006680 Amidohydrolase-related GO:0016787 A4G23_RS24110 e7914c56929becffaa4fb9c109cc429b 467 Gene3D G3DSA:2.30.40.10 383 458 1.1E-14 T 10-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A4G23_RS01820 83b81bdd80ea879a64c2be65c6e65b35 254 Pfam PF13847 Methyltransferase domain 38 166 5.9E-12 T 10-11-2016 IPR025714 Methyltransferase domain A4G23_RS01820 83b81bdd80ea879a64c2be65c6e65b35 254 SUPERFAMILY SSF53335 16 247 9.53E-33 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS01820 83b81bdd80ea879a64c2be65c6e65b35 254 Gene3D G3DSA:3.40.50.150 14 249 4.0E-36 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS16170 d986e9aa50a89fb9f2365bdc53f3b289 223 Pfam PF00196 Bacterial regulatory proteins, luxR family 160 204 6.3E-13 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS16170 d986e9aa50a89fb9f2365bdc53f3b289 223 SUPERFAMILY SSF52172 4 175 1.39E-14 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS16170 d986e9aa50a89fb9f2365bdc53f3b289 223 SMART SM00421 157 219 2.1E-13 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS16170 d986e9aa50a89fb9f2365bdc53f3b289 223 SMART SM00448 5 129 1.8E-8 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS16170 d986e9aa50a89fb9f2365bdc53f3b289 223 Pfam PF00072 Response regulator receiver domain 7 117 3.5E-13 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS16170 d986e9aa50a89fb9f2365bdc53f3b289 223 Gene3D G3DSA:3.40.50.2300 4 157 2.2E-24 T 10-11-2016 A4G23_RS16170 d986e9aa50a89fb9f2365bdc53f3b289 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 190 202 3.4E-10 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS16170 d986e9aa50a89fb9f2365bdc53f3b289 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 174 3.4E-10 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS16170 d986e9aa50a89fb9f2365bdc53f3b289 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 174 190 3.4E-10 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS16170 d986e9aa50a89fb9f2365bdc53f3b289 223 Gene3D G3DSA:1.10.10.10 158 222 9.1E-24 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS03990 4a4e9e7e803a79577b35e35794ed84f5 178 Hamap MF_00173 Arginine repressor [argR]. 1 177 56.979 T 10-11-2016 IPR001669 Arginine repressor GO:0003700|GO:0006355 A4G23_RS03990 4a4e9e7e803a79577b35e35794ed84f5 178 SUPERFAMILY SSF55252 107 172 2.49E-18 T 10-11-2016 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 A4G23_RS03990 4a4e9e7e803a79577b35e35794ed84f5 178 TIGRFAM TIGR01529 argR_whole: arginine repressor 20 173 5.4E-43 T 10-11-2016 IPR001669 Arginine repressor GO:0003700|GO:0006355 A4G23_RS03990 4a4e9e7e803a79577b35e35794ed84f5 178 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 117 152 2.0E-12 T 10-11-2016 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 A4G23_RS03990 4a4e9e7e803a79577b35e35794ed84f5 178 Pfam PF02863 Arginine repressor, C-terminal domain 107 170 5.3E-23 T 10-11-2016 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 A4G23_RS03990 4a4e9e7e803a79577b35e35794ed84f5 178 Pfam PF01316 Arginine repressor, DNA binding domain 17 84 1.1E-24 T 10-11-2016 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 A4G23_RS03990 4a4e9e7e803a79577b35e35794ed84f5 178 SUPERFAMILY SSF46785 16 85 5.79E-20 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS03990 4a4e9e7e803a79577b35e35794ed84f5 178 Gene3D G3DSA:1.10.10.10 14 87 8.4E-28 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS03990 4a4e9e7e803a79577b35e35794ed84f5 178 PRINTS PR01467 Bacterial arginine repressor signature 143 158 2.5E-26 T 10-11-2016 IPR001669 Arginine repressor GO:0003700|GO:0006355 A4G23_RS03990 4a4e9e7e803a79577b35e35794ed84f5 178 PRINTS PR01467 Bacterial arginine repressor signature 113 126 2.5E-26 T 10-11-2016 IPR001669 Arginine repressor GO:0003700|GO:0006355 A4G23_RS03990 4a4e9e7e803a79577b35e35794ed84f5 178 PRINTS PR01467 Bacterial arginine repressor signature 52 67 2.5E-26 T 10-11-2016 IPR001669 Arginine repressor GO:0003700|GO:0006355 A4G23_RS03990 4a4e9e7e803a79577b35e35794ed84f5 178 PRINTS PR01467 Bacterial arginine repressor signature 36 49 2.5E-26 T 10-11-2016 IPR001669 Arginine repressor GO:0003700|GO:0006355 A4G23_RS03990 4a4e9e7e803a79577b35e35794ed84f5 178 Gene3D G3DSA:3.30.1360.40 98 173 1.1E-27 T 10-11-2016 IPR024946 Arginine repressor C-terminal-like domain A4G23_RS22100 0acd9fdbd7767437d898dbdb45b65126 278 Gene3D G3DSA:3.40.50.1820 15 252 1.1E-31 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS22100 0acd9fdbd7767437d898dbdb45b65126 278 Pfam PF00975 Thioesterase domain 31 248 1.1E-37 T 10-11-2016 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 A4G23_RS22100 0acd9fdbd7767437d898dbdb45b65126 278 SUPERFAMILY SSF53474 25 252 1.66E-38 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS21645 3f558e5527d2676452ac1f7bedac884a 541 Pfam PF00550 Phosphopantetheine attachment site 16 76 6.9E-14 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS21645 3f558e5527d2676452ac1f7bedac884a 541 Gene3D G3DSA:1.10.1200.10 16 79 5.1E-17 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS21645 3f558e5527d2676452ac1f7bedac884a 541 SMART SM00823 Phosphopantetheine attachment site 8 80 4.9E-13 T 10-11-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4G23_RS21645 3f558e5527d2676452ac1f7bedac884a 541 SUPERFAMILY SSF52777 109 288 5.78E-38 T 10-11-2016 A4G23_RS21645 3f558e5527d2676452ac1f7bedac884a 541 Pfam PF13745 HxxPF-repeated domain 429 520 4.1E-15 T 10-11-2016 A4G23_RS21645 3f558e5527d2676452ac1f7bedac884a 541 Pfam PF00668 Condensation domain 106 405 4.3E-49 T 10-11-2016 IPR001242 Condensation domain A4G23_RS21645 3f558e5527d2676452ac1f7bedac884a 541 SUPERFAMILY SSF52777 303 534 1.45E-38 T 10-11-2016 A4G23_RS21645 3f558e5527d2676452ac1f7bedac884a 541 ProSitePatterns PS00012 Phosphopantetheine attachment site. 35 50 - T 10-11-2016 IPR006162 Phosphopantetheine attachment site A4G23_RS21645 3f558e5527d2676452ac1f7bedac884a 541 SUPERFAMILY SSF47336 10 119 1.7E-18 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS25130 bd0a5e767e7a2fd610c67466ccef7b5d 411 Gene3D G3DSA:3.30.565.10 297 404 3.7E-12 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS25130 bd0a5e767e7a2fd610c67466ccef7b5d 411 SUPERFAMILY SSF55874 291 404 1.96E-13 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS25130 bd0a5e767e7a2fd610c67466ccef7b5d 411 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 299 401 7.0E-5 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS17550 82b9c23dea0bb48e6b4d471f50095149 465 SUPERFAMILY SSF56784 292 440 2.23E-30 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS17550 82b9c23dea0bb48e6b4d471f50095149 465 Gene3D G3DSA:3.90.550.10 200 278 2.5E-68 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS17550 82b9c23dea0bb48e6b4d471f50095149 465 Gene3D G3DSA:3.90.550.10 6 143 2.5E-68 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS17550 82b9c23dea0bb48e6b4d471f50095149 465 Gene3D G3DSA:3.40.50.1000 291 439 6.8E-33 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS17550 82b9c23dea0bb48e6b4d471f50095149 465 SUPERFAMILY SSF53448 203 278 9.97E-49 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS17550 82b9c23dea0bb48e6b4d471f50095149 465 SUPERFAMILY SSF53448 6 143 9.97E-49 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS17550 82b9c23dea0bb48e6b4d471f50095149 465 Pfam PF08282 haloacid dehalogenase-like hydrolase 367 425 2.3E-9 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS17550 82b9c23dea0bb48e6b4d471f50095149 465 Pfam PF02348 Cytidylyltransferase 9 134 7.7E-22 T 10-11-2016 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 A4G23_RS01220 5b6b0eafeb024dafd06bcb974322f3d8 325 PRINTS PR01438 Universal stress protein signature 7 25 1.2E-8 T 10-11-2016 IPR006015 Universal stress protein A A4G23_RS01220 5b6b0eafeb024dafd06bcb974322f3d8 325 PRINTS PR01438 Universal stress protein signature 99 111 1.2E-8 T 10-11-2016 IPR006015 Universal stress protein A A4G23_RS01220 5b6b0eafeb024dafd06bcb974322f3d8 325 PRINTS PR01438 Universal stress protein signature 117 139 1.2E-8 T 10-11-2016 IPR006015 Universal stress protein A A4G23_RS01220 5b6b0eafeb024dafd06bcb974322f3d8 325 Gene3D G3DSA:3.40.50.620 134 284 4.9E-20 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS01220 5b6b0eafeb024dafd06bcb974322f3d8 325 Gene3D G3DSA:3.40.50.620 8 133 3.4E-27 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS01220 5b6b0eafeb024dafd06bcb974322f3d8 325 SUPERFAMILY SSF52402 9 140 8.37E-24 T 10-11-2016 A4G23_RS01220 5b6b0eafeb024dafd06bcb974322f3d8 325 Pfam PF00582 Universal stress protein family 9 139 2.2E-18 T 10-11-2016 IPR006016 UspA GO:0006950 A4G23_RS01220 5b6b0eafeb024dafd06bcb974322f3d8 325 Pfam PF00582 Universal stress protein family 152 284 3.7E-15 T 10-11-2016 IPR006016 UspA GO:0006950 A4G23_RS01220 5b6b0eafeb024dafd06bcb974322f3d8 325 SUPERFAMILY SSF52402 149 287 3.93E-19 T 10-11-2016 A4G23_RS21220 0c0eea936db951bcdcee260cdf26f4e2 340 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 19 338 4.6E-77 T 10-11-2016 IPR011852 TRAP transporter solute receptor, TAXI family A4G23_RS21220 0c0eea936db951bcdcee260cdf26f4e2 340 SUPERFAMILY SSF53850 50 336 7.56E-56 T 10-11-2016 A4G23_RS21220 0c0eea936db951bcdcee260cdf26f4e2 340 Gene3D G3DSA:3.40.190.10 134 271 3.0E-34 T 10-11-2016 A4G23_RS21220 0c0eea936db951bcdcee260cdf26f4e2 340 Gene3D G3DSA:3.40.190.10 272 336 1.5E-27 T 10-11-2016 A4G23_RS21220 0c0eea936db951bcdcee260cdf26f4e2 340 Gene3D G3DSA:3.40.190.10 51 130 1.5E-27 T 10-11-2016 A4G23_RS21220 0c0eea936db951bcdcee260cdf26f4e2 340 Pfam PF16868 NMT1-like family 55 336 1.4E-50 T 10-11-2016 IPR011852 TRAP transporter solute receptor, TAXI family A4G23_RS08120 11fbe0f76ab2da46d196fc44eace1e18 404 SUPERFAMILY SSF53756 2 377 8.48E-69 T 10-11-2016 A4G23_RS08120 11fbe0f76ab2da46d196fc44eace1e18 404 Pfam PF13439 Glycosyltransferase Family 4 13 191 5.4E-9 T 10-11-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A4G23_RS08120 11fbe0f76ab2da46d196fc44eace1e18 404 Gene3D G3DSA:3.40.50.2000 197 357 7.2E-25 T 10-11-2016 A4G23_RS08120 11fbe0f76ab2da46d196fc44eace1e18 404 Pfam PF00534 Glycosyl transferases group 1 204 357 4.7E-37 T 10-11-2016 IPR001296 Glycosyl transferase, family 1 A4G23_RS22580 175f6e927df31818f77d3a19e27cccd4 248 Gene3D G3DSA:3.20.20.140 67 247 8.4E-12 T 10-11-2016 A4G23_RS22580 175f6e927df31818f77d3a19e27cccd4 248 SUPERFAMILY SSF51556 23 247 2.04E-16 T 10-11-2016 IPR032466 Metal-dependent hydrolase A4G23_RS05660 6153673074a448c23fb24028f90a5df2 95 Pfam PF13397 RNA polymerase-binding protein 1 92 1.4E-36 T 10-11-2016 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 A4G23_RS05660 6153673074a448c23fb24028f90a5df2 95 ProSitePatterns PS00202 Rubredoxin signature. 35 45 - T 10-11-2016 IPR018527 Rubredoxin, iron-binding site GO:0046872 A4G23_RS05660 6153673074a448c23fb24028f90a5df2 95 Hamap MF_01483 RNA polymerase-binding protein RbpA [rbpA]. 1 94 23.84 T 10-11-2016 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 A4G23_RS15610 1f314868f51ca4a0ae6be01777ecaf9f 312 Pfam PF12710 haloacid dehalogenase-like hydrolase 62 248 4.7E-28 T 10-11-2016 A4G23_RS15610 1f314868f51ca4a0ae6be01777ecaf9f 312 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 61 251 7.0E-16 T 10-11-2016 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 A4G23_RS15610 1f314868f51ca4a0ae6be01777ecaf9f 312 SUPERFAMILY SSF56784 60 274 1.28E-30 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS15610 1f314868f51ca4a0ae6be01777ecaf9f 312 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 61 263 9.4E-55 T 10-11-2016 IPR006385 HAD-superfamily hydrolase, subfamily IB, PSPase-like, bacterial A4G23_RS15610 1f314868f51ca4a0ae6be01777ecaf9f 312 Gene3D G3DSA:3.40.50.1000 134 278 3.9E-48 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS06180 aa4d5a01a84288b985cdf767e0adfdc8 155 SUPERFAMILY SSF55729 4 153 1.54E-38 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS06180 aa4d5a01a84288b985cdf767e0adfdc8 155 Pfam PF13673 Acetyltransferase (GNAT) domain 25 154 5.1E-18 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS06180 aa4d5a01a84288b985cdf767e0adfdc8 155 Gene3D G3DSA:3.40.630.30 10 153 1.4E-37 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS09435 9612a68e090732b1811756fa2d478d8f 421 Pfam PF02378 Phosphotransferase system, EIIC 27 340 5.7E-73 T 10-11-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 A4G23_RS10870 1b6e176a259ed93756b01a93e13b08c1 162 Pfam PF00994 Probable molybdopterin binding domain 7 145 1.4E-28 T 10-11-2016 IPR001453 MoaB/Mog domain A4G23_RS10870 1b6e176a259ed93756b01a93e13b08c1 162 Gene3D G3DSA:3.40.980.10 3 154 3.6E-51 T 10-11-2016 IPR001453 MoaB/Mog domain A4G23_RS10870 1b6e176a259ed93756b01a93e13b08c1 162 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 64 77 - T 10-11-2016 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 A4G23_RS10870 1b6e176a259ed93756b01a93e13b08c1 162 SMART SM00852 6 148 5.5E-21 T 10-11-2016 IPR001453 MoaB/Mog domain A4G23_RS10870 1b6e176a259ed93756b01a93e13b08c1 162 SUPERFAMILY SSF53218 3 153 2.88E-41 T 10-11-2016 IPR001453 MoaB/Mog domain A4G23_RS10870 1b6e176a259ed93756b01a93e13b08c1 162 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 3 140 1.2E-30 T 10-11-2016 IPR001453 MoaB/Mog domain A4G23_RS16770 5a9d2d1bbf473ad27e4f292e63385c56 172 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 42 172 32.773 T 10-11-2016 IPR023035 Ribosomal protein S9, bacterial/plastid A4G23_RS16770 5a9d2d1bbf473ad27e4f292e63385c56 172 Gene3D G3DSA:3.30.230.10 48 172 6.7E-47 T 10-11-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A4G23_RS16770 5a9d2d1bbf473ad27e4f292e63385c56 172 SUPERFAMILY SSF54211 48 172 3.79E-42 T 10-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold A4G23_RS16770 5a9d2d1bbf473ad27e4f292e63385c56 172 ProSitePatterns PS00360 Ribosomal protein S9 signature. 110 128 - T 10-11-2016 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 A4G23_RS16770 5a9d2d1bbf473ad27e4f292e63385c56 172 Pfam PF00380 Ribosomal protein S9/S16 51 172 5.3E-43 T 10-11-2016 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 A4G23_RS18290 65513a1a10c5ac2ff69d0a3091e8d84c 67 SUPERFAMILY SSF116842 2 60 2.22E-15 T 10-11-2016 A4G23_RS18290 65513a1a10c5ac2ff69d0a3091e8d84c 67 Gene3D G3DSA:1.10.287.1040 2 61 3.2E-21 T 10-11-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 A4G23_RS18290 65513a1a10c5ac2ff69d0a3091e8d84c 67 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 2 62 13.525 T 10-11-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 A4G23_RS18290 65513a1a10c5ac2ff69d0a3091e8d84c 67 PIRSF PIRSF006488 1 67 9.2E-22 T 10-11-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 A4G23_RS18290 65513a1a10c5ac2ff69d0a3091e8d84c 67 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 3 57 6.1E-20 T 10-11-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 A4G23_RS18290 65513a1a10c5ac2ff69d0a3091e8d84c 67 Pfam PF02609 Exonuclease VII small subunit 3 52 3.5E-17 T 10-11-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 A4G23_RS18290 65513a1a10c5ac2ff69d0a3091e8d84c 67 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 1 41 6.0E-14 T 10-11-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 A4G23_RS08035 03e6eb226b87adb8143ac5d6857a9845 955 SUPERFAMILY SSF47323 770 953 1.79E-28 T 10-11-2016 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4G23_RS08035 03e6eb226b87adb8143ac5d6857a9845 955 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 18 954 21.282 T 10-11-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A4G23_RS08035 03e6eb226b87adb8143ac5d6857a9845 955 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 221 953 4.0E-213 T 10-11-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A4G23_RS08035 03e6eb226b87adb8143ac5d6857a9845 955 Gene3D G3DSA:1.10.730.10 755 890 2.5E-34 T 10-11-2016 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4G23_RS08035 03e6eb226b87adb8143ac5d6857a9845 955 PRINTS PR00985 Leucyl-tRNA synthetase signature 643 665 1.8E-52 T 10-11-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A4G23_RS08035 03e6eb226b87adb8143ac5d6857a9845 955 PRINTS PR00985 Leucyl-tRNA synthetase signature 595 613 1.8E-52 T 10-11-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A4G23_RS08035 03e6eb226b87adb8143ac5d6857a9845 955 PRINTS PR00985 Leucyl-tRNA synthetase signature 676 686 1.8E-52 T 10-11-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A4G23_RS08035 03e6eb226b87adb8143ac5d6857a9845 955 PRINTS PR00985 Leucyl-tRNA synthetase signature 226 242 1.8E-52 T 10-11-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A4G23_RS08035 03e6eb226b87adb8143ac5d6857a9845 955 PRINTS PR00985 Leucyl-tRNA synthetase signature 288 307 1.8E-52 T 10-11-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A4G23_RS08035 03e6eb226b87adb8143ac5d6857a9845 955 PRINTS PR00985 Leucyl-tRNA synthetase signature 259 272 1.8E-52 T 10-11-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A4G23_RS08035 03e6eb226b87adb8143ac5d6857a9845 955 PRINTS PR00985 Leucyl-tRNA synthetase signature 152 169 1.8E-52 T 10-11-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A4G23_RS08035 03e6eb226b87adb8143ac5d6857a9845 955 SUPERFAMILY SSF50677 299 510 6.8E-44 T 10-11-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A4G23_RS08035 03e6eb226b87adb8143ac5d6857a9845 955 Gene3D G3DSA:3.40.50.620 520 692 7.2E-136 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS08035 03e6eb226b87adb8143ac5d6857a9845 955 Gene3D G3DSA:3.40.50.620 725 754 7.2E-136 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS08035 03e6eb226b87adb8143ac5d6857a9845 955 Gene3D G3DSA:3.40.50.620 220 296 7.2E-136 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS08035 03e6eb226b87adb8143ac5d6857a9845 955 Gene3D G3DSA:3.40.50.620 22 171 7.2E-136 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS08035 03e6eb226b87adb8143ac5d6857a9845 955 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 294 499 1.7E-56 T 10-11-2016 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 A4G23_RS08035 03e6eb226b87adb8143ac5d6857a9845 955 Gene3D G3DSA:3.90.740.10 297 519 6.9E-51 T 10-11-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A4G23_RS08035 03e6eb226b87adb8143ac5d6857a9845 955 Pfam PF09334 tRNA synthetases class I (M) 65 167 2.0E-13 T 10-11-2016 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4G23_RS08035 03e6eb226b87adb8143ac5d6857a9845 955 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 68 78 - T 10-11-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4G23_RS08035 03e6eb226b87adb8143ac5d6857a9845 955 SUPERFAMILY SSF52374 23 172 1.28E-114 T 10-11-2016 A4G23_RS08035 03e6eb226b87adb8143ac5d6857a9845 955 SUPERFAMILY SSF52374 511 774 1.28E-114 T 10-11-2016 A4G23_RS08035 03e6eb226b87adb8143ac5d6857a9845 955 SUPERFAMILY SSF52374 221 299 1.28E-114 T 10-11-2016 A4G23_RS08035 03e6eb226b87adb8143ac5d6857a9845 955 Pfam PF08264 Anticodon-binding domain of tRNA 804 916 1.1E-15 T 10-11-2016 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 A4G23_RS06905 bbb77756905e7afd95771a2b25b1870d 218 Pfam PF11303 Protein of unknown function (DUF3105) 85 207 9.0E-44 T 10-11-2016 IPR021454 Protein of unknown function DUF3105 A4G23_RS18455 b5516711dc43a4f799302ea7f570de7e 391 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 237 313 4.7E-23 T 10-11-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A4G23_RS18455 b5516711dc43a4f799302ea7f570de7e 391 Pfam PF00005 ABC transporter 36 187 2.1E-33 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS18455 b5516711dc43a4f799302ea7f570de7e 391 SUPERFAMILY SSF52540 7 259 3.19E-77 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS18455 b5516711dc43a4f799302ea7f570de7e 391 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 239 306 1.3E-17 T 10-11-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A4G23_RS18455 b5516711dc43a4f799302ea7f570de7e 391 Gene3D G3DSA:3.40.50.300 6 261 2.2E-85 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS18455 b5516711dc43a4f799302ea7f570de7e 391 SMART SM00382 44 237 2.4E-15 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS18455 b5516711dc43a4f799302ea7f570de7e 391 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS09195 3ba6b22c5bc79eb9edd6476e598b8e37 198 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 193 3.1E-49 T 10-11-2016 IPR013078 Histidine phosphatase superfamily, clade-1 A4G23_RS09195 3ba6b22c5bc79eb9edd6476e598b8e37 198 SUPERFAMILY SSF53254 1 197 6.85E-49 T 10-11-2016 IPR029033 Histidine phosphatase superfamily A4G23_RS09195 3ba6b22c5bc79eb9edd6476e598b8e37 198 Gene3D G3DSA:3.40.50.1240 1 197 1.9E-47 T 10-11-2016 IPR029033 Histidine phosphatase superfamily A4G23_RS09195 3ba6b22c5bc79eb9edd6476e598b8e37 198 SMART SM00855 4 153 3.7E-22 T 10-11-2016 IPR013078 Histidine phosphatase superfamily, clade-1 A4G23_RS15905 ec3a13e3e1d49521314820296c145b2f 387 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 52 368 7.3E-92 T 10-11-2016 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 A4G23_RS15905 ec3a13e3e1d49521314820296c145b2f 387 SUPERFAMILY SSF102114 16 361 2.62E-44 T 10-11-2016 A4G23_RS15905 ec3a13e3e1d49521314820296c145b2f 387 Pfam PF04055 Radical SAM superfamily 61 229 3.7E-10 T 10-11-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 A4G23_RS15905 ec3a13e3e1d49521314820296c145b2f 387 TIGRFAM TIGR03700 mena_SCO4494: putative menaquinone biosynthesis radical SAM enzyme, SCO4494 family 10 367 1.9E-163 T 10-11-2016 IPR022432 Aminodeoxyfutalosine synthase GO:0009234 KEGG: 00130+2.5.1.120|MetaCyc: PWY-7371|MetaCyc: PWY-7374 A4G23_RS15905 ec3a13e3e1d49521314820296c145b2f 387 Gene3D G3DSA:3.20.20.70 17 360 9.1E-56 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS15905 ec3a13e3e1d49521314820296c145b2f 387 Hamap MF_00993 Aminodeoxyfutalosine synthase [mqnE]. 7 371 48.399 T 10-11-2016 IPR022432 Aminodeoxyfutalosine synthase GO:0009234 KEGG: 00130+2.5.1.120|MetaCyc: PWY-7371|MetaCyc: PWY-7374 A4G23_RS15905 ec3a13e3e1d49521314820296c145b2f 387 PIRSF PIRSF004762 1 381 1.0E-101 T 10-11-2016 IPR005244 FO synthase, subunit 2-like GO:0016765|GO:0051188|GO:0051539 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 A4G23_RS04355 cddb4895750c6979c7ac8529d1d71c0a 533 Gene3D G3DSA:3.10.105.10 288 500 1.2E-41 T 10-11-2016 A4G23_RS04355 cddb4895750c6979c7ac8529d1d71c0a 533 Gene3D G3DSA:3.90.76.10 50 204 1.3E-30 T 10-11-2016 A4G23_RS04355 cddb4895750c6979c7ac8529d1d71c0a 533 PIRSF PIRSF002741 2 525 3.1E-60 T 10-11-2016 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A4G23_RS04355 cddb4895750c6979c7ac8529d1d71c0a 533 SUPERFAMILY SSF53850 46 527 2.17E-96 T 10-11-2016 A4G23_RS04355 cddb4895750c6979c7ac8529d1d71c0a 533 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 84 450 4.6E-66 T 10-11-2016 IPR000914 Solute-binding protein family 5 domain A4G23_RS15715 0f3543fc1f1e30f00ffc638d1620dce1 331 SMART SM01004 7 329 2.2E-211 T 10-11-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4G23_RS15715 0f3543fc1f1e30f00ffc638d1620dce1 331 SUPERFAMILY SSF51569 5 330 5.86E-130 T 10-11-2016 A4G23_RS15715 0f3543fc1f1e30f00ffc638d1620dce1 331 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 128 142 5.8E-56 T 10-11-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4G23_RS15715 0f3543fc1f1e30f00ffc638d1620dce1 331 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 197 216 5.8E-56 T 10-11-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4G23_RS15715 0f3543fc1f1e30f00ffc638d1620dce1 331 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 273 288 5.8E-56 T 10-11-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4G23_RS15715 0f3543fc1f1e30f00ffc638d1620dce1 331 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 303 322 5.8E-56 T 10-11-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4G23_RS15715 0f3543fc1f1e30f00ffc638d1620dce1 331 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 159 178 5.8E-56 T 10-11-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4G23_RS15715 0f3543fc1f1e30f00ffc638d1620dce1 331 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 248 264 5.8E-56 T 10-11-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4G23_RS15715 0f3543fc1f1e30f00ffc638d1620dce1 331 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 248 260 - T 10-11-2016 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4G23_RS15715 0f3543fc1f1e30f00ffc638d1620dce1 331 Gene3D G3DSA:3.20.20.70 7 330 1.8E-142 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS15715 0f3543fc1f1e30f00ffc638d1620dce1 331 PIRSF PIRSF001415 1 331 1.8E-146 T 10-11-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4G23_RS15715 0f3543fc1f1e30f00ffc638d1620dce1 331 Pfam PF00490 Delta-aminolevulinic acid dehydratase 10 327 1.9E-137 T 10-11-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4G23_RS09825 549f74120201f505d10cdfa77f2ae392 193 Pfam PF13302 Acetyltransferase (GNAT) domain 10 151 4.9E-26 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS09825 549f74120201f505d10cdfa77f2ae392 193 Gene3D G3DSA:3.40.630.30 1 178 4.4E-46 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS09825 549f74120201f505d10cdfa77f2ae392 193 SUPERFAMILY SSF55729 1 175 1.56E-38 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS21685 5f7d671819c886249b0e9f66d717ab6c 2095 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1609 1624 - T 10-11-2016 IPR006162 Phosphopantetheine attachment site A4G23_RS21685 5f7d671819c886249b0e9f66d717ab6c 2095 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1090 1491 4.3E-132 T 10-11-2016 IPR010071 Amino acid adenylation domain A4G23_RS21685 5f7d671819c886249b0e9f66d717ab6c 2095 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 26 437 7.1E-129 T 10-11-2016 IPR010071 Amino acid adenylation domain A4G23_RS21685 5f7d671819c886249b0e9f66d717ab6c 2095 SUPERFAMILY SSF56801 1024 1597 2.88E-156 T 10-11-2016 A4G23_RS21685 5f7d671819c886249b0e9f66d717ab6c 2095 Gene3D G3DSA:3.30.300.30 1462 1564 2.9E-33 T 10-11-2016 A4G23_RS21685 5f7d671819c886249b0e9f66d717ab6c 2095 Gene3D G3DSA:3.30.300.30 407 503 2.5E-25 T 10-11-2016 A4G23_RS21685 5f7d671819c886249b0e9f66d717ab6c 2095 SUPERFAMILY SSF56801 1 505 3.27E-146 T 10-11-2016 A4G23_RS21685 5f7d671819c886249b0e9f66d717ab6c 2095 SUPERFAMILY SSF52777 606 778 8.12E-37 T 10-11-2016 A4G23_RS21685 5f7d671819c886249b0e9f66d717ab6c 2095 SUPERFAMILY SSF52777 1675 1846 1.22E-38 T 10-11-2016 A4G23_RS21685 5f7d671819c886249b0e9f66d717ab6c 2095 Gene3D G3DSA:3.40.50.980 1057 1216 1.9E-45 T 10-11-2016 A4G23_RS21685 5f7d671819c886249b0e9f66d717ab6c 2095 Gene3D G3DSA:3.40.50.980 1 165 1.4E-50 T 10-11-2016 A4G23_RS21685 5f7d671819c886249b0e9f66d717ab6c 2095 ProSitePatterns PS00455 Putative AMP-binding domain signature. 157 168 - T 10-11-2016 IPR020845 AMP-binding, conserved site A4G23_RS21685 5f7d671819c886249b0e9f66d717ab6c 2095 Gene3D G3DSA:1.10.1200.10 516 588 2.1E-16 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS21685 5f7d671819c886249b0e9f66d717ab6c 2095 Gene3D G3DSA:1.10.1200.10 1584 1652 6.2E-21 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS21685 5f7d671819c886249b0e9f66d717ab6c 2095 SUPERFAMILY SSF52777 787 1031 4.34E-49 T 10-11-2016 A4G23_RS21685 5f7d671819c886249b0e9f66d717ab6c 2095 SUPERFAMILY SSF52777 1852 2089 5.0E-42 T 10-11-2016 A4G23_RS21685 5f7d671819c886249b0e9f66d717ab6c 2095 Pfam PF00501 AMP-binding enzyme 1064 1468 4.9E-97 T 10-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A4G23_RS21685 5f7d671819c886249b0e9f66d717ab6c 2095 Pfam PF00501 AMP-binding enzyme 7 412 2.4E-99 T 10-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A4G23_RS21685 5f7d671819c886249b0e9f66d717ab6c 2095 Pfam PF13193 AMP-binding enzyme C-terminal domain 421 492 1.8E-6 T 10-11-2016 IPR025110 AMP-binding enzyme C-terminal domain A4G23_RS21685 5f7d671819c886249b0e9f66d717ab6c 2095 Pfam PF13193 AMP-binding enzyme C-terminal domain 1476 1552 2.4E-11 T 10-11-2016 IPR025110 AMP-binding enzyme C-terminal domain A4G23_RS21685 5f7d671819c886249b0e9f66d717ab6c 2095 SUPERFAMILY SSF47336 515 586 2.88E-14 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS21685 5f7d671819c886249b0e9f66d717ab6c 2095 Gene3D G3DSA:3.40.50.980 166 316 5.7E-43 T 10-11-2016 A4G23_RS21685 5f7d671819c886249b0e9f66d717ab6c 2095 Gene3D G3DSA:3.40.50.980 1217 1379 4.8E-47 T 10-11-2016 A4G23_RS21685 5f7d671819c886249b0e9f66d717ab6c 2095 SMART SM00823 Phosphopantetheine attachment site 1585 1659 0.015 T 10-11-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4G23_RS21685 5f7d671819c886249b0e9f66d717ab6c 2095 SMART SM00823 Phosphopantetheine attachment site 521 590 3.9E-4 T 10-11-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4G23_RS21685 5f7d671819c886249b0e9f66d717ab6c 2095 Gene3D G3DSA:2.30.38.10 324 402 2.7E-22 T 10-11-2016 A4G23_RS21685 5f7d671819c886249b0e9f66d717ab6c 2095 Gene3D G3DSA:2.30.38.10 1380 1457 2.2E-26 T 10-11-2016 A4G23_RS21685 5f7d671819c886249b0e9f66d717ab6c 2095 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1211 1222 - T 10-11-2016 IPR020845 AMP-binding, conserved site A4G23_RS21685 5f7d671819c886249b0e9f66d717ab6c 2095 SUPERFAMILY SSF47336 1585 1650 2.49E-16 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS21685 5f7d671819c886249b0e9f66d717ab6c 2095 Pfam PF13745 HxxPF-repeated domain 1982 2071 1.6E-11 T 10-11-2016 A4G23_RS21685 5f7d671819c886249b0e9f66d717ab6c 2095 Pfam PF13745 HxxPF-repeated domain 920 1010 5.2E-20 T 10-11-2016 A4G23_RS21685 5f7d671819c886249b0e9f66d717ab6c 2095 Pfam PF00668 Condensation domain 1671 1959 1.1E-50 T 10-11-2016 IPR001242 Condensation domain A4G23_RS21685 5f7d671819c886249b0e9f66d717ab6c 2095 Pfam PF00668 Condensation domain 605 897 1.4E-45 T 10-11-2016 IPR001242 Condensation domain A4G23_RS21685 5f7d671819c886249b0e9f66d717ab6c 2095 Pfam PF00550 Phosphopantetheine attachment site 1587 1650 6.6E-13 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS21685 5f7d671819c886249b0e9f66d717ab6c 2095 Pfam PF00550 Phosphopantetheine attachment site 523 586 5.8E-9 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS13265 979830267ca8c291773209b2a3a47509 225 Pfam PF00588 SpoU rRNA Methylase family 75 211 4.0E-21 T 10-11-2016 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 A4G23_RS13265 979830267ca8c291773209b2a3a47509 225 Gene3D G3DSA:3.40.1280.10 55 216 1.6E-38 T 10-11-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A4G23_RS13265 979830267ca8c291773209b2a3a47509 225 SUPERFAMILY SSF75217 59 217 2.62E-35 T 10-11-2016 IPR029028 Alpha/beta knot methyltransferases A4G23_RS22450 765214e13356623e2be3cfde619de663 164 SUPERFAMILY SSF55874 66 159 5.24E-11 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS22450 765214e13356623e2be3cfde619de663 164 Pfam PF13581 Histidine kinase-like ATPase domain 45 160 1.2E-15 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS22450 765214e13356623e2be3cfde619de663 164 Gene3D G3DSA:3.30.565.10 54 158 5.3E-7 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS00325 54c3a43d6cb546bbbbd646f0806cc2ee 806 Gene3D G3DSA:3.30.450.20 423 547 1.4E-14 T 10-11-2016 A4G23_RS00325 54c3a43d6cb546bbbbd646f0806cc2ee 806 SUPERFAMILY SSF81606 613 801 6.8E-9 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS00325 54c3a43d6cb546bbbbd646f0806cc2ee 806 Pfam PF03861 ANTAR domain 45 97 2.0E-10 T 10-11-2016 IPR005561 ANTAR domain GO:0003723 A4G23_RS00325 54c3a43d6cb546bbbbd646f0806cc2ee 806 SMART SM01012 42 97 1.0E-10 T 10-11-2016 IPR005561 ANTAR domain GO:0003723 A4G23_RS00325 54c3a43d6cb546bbbbd646f0806cc2ee 806 SMART SM00331 597 805 2.8E-33 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS00325 54c3a43d6cb546bbbbd646f0806cc2ee 806 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 624 804 1.0E-46 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS00325 54c3a43d6cb546bbbbd646f0806cc2ee 806 Pfam PF08447 PAS fold 456 541 5.1E-7 T 10-11-2016 IPR013655 PAS fold-3 GO:0005515 A4G23_RS00325 54c3a43d6cb546bbbbd646f0806cc2ee 806 Gene3D G3DSA:1.10.10.10 46 100 9.6E-6 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS00325 54c3a43d6cb546bbbbd646f0806cc2ee 806 SUPERFAMILY SSF55781 148 287 1.18E-6 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS00325 54c3a43d6cb546bbbbd646f0806cc2ee 806 SUPERFAMILY SSF55785 450 547 3.84E-10 T 10-11-2016 IPR000014 PAS domain A4G23_RS00325 54c3a43d6cb546bbbbd646f0806cc2ee 806 Gene3D G3DSA:3.30.450.40 141 283 1.3E-5 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS16310 ddfadc0383bd84c9ebc8e12bf579bb8e 177 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 18 163 4.8E-23 T 10-11-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS16310 ddfadc0383bd84c9ebc8e12bf579bb8e 177 SUPERFAMILY SSF88659 105 164 7.48E-17 T 10-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS16310 ddfadc0383bd84c9ebc8e12bf579bb8e 177 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 9 165 3.7E-51 T 10-11-2016 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 A4G23_RS16310 ddfadc0383bd84c9ebc8e12bf579bb8e 177 Gene3D G3DSA:1.10.10.10 107 164 5.7E-22 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS16310 ddfadc0383bd84c9ebc8e12bf579bb8e 177 Pfam PF08281 Sigma-70, region 4 109 162 4.5E-18 T 10-11-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS16310 ddfadc0383bd84c9ebc8e12bf579bb8e 177 Gene3D G3DSA:1.10.1740.10 9 83 5.1E-13 T 10-11-2016 A4G23_RS16310 ddfadc0383bd84c9ebc8e12bf579bb8e 177 Pfam PF04542 Sigma-70 region 2 22 83 9.2E-8 T 10-11-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS16310 ddfadc0383bd84c9ebc8e12bf579bb8e 177 SUPERFAMILY SSF88946 9 93 1.96E-12 T 10-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS20515 484c9d6133ca7bd641cceb6851f17d23 273 SUPERFAMILY SSF75217 1 247 1.13E-83 T 10-11-2016 IPR029028 Alpha/beta knot methyltransferases A4G23_RS20515 484c9d6133ca7bd641cceb6851f17d23 273 Gene3D G3DSA:1.10.1270.20 168 255 7.2E-29 T 10-11-2016 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 A4G23_RS20515 484c9d6133ca7bd641cceb6851f17d23 273 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 273 98.801 T 10-11-2016 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 A4G23_RS20515 484c9d6133ca7bd641cceb6851f17d23 273 Gene3D G3DSA:3.40.1280.10 1 167 2.9E-61 T 10-11-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A4G23_RS20515 484c9d6133ca7bd641cceb6851f17d23 273 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 22 232 2.6E-70 T 10-11-2016 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 A4G23_RS20515 484c9d6133ca7bd641cceb6851f17d23 273 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 238 8.2E-65 T 10-11-2016 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 A4G23_RS20515 484c9d6133ca7bd641cceb6851f17d23 273 PIRSF PIRSF000386 1 259 1.6E-93 T 10-11-2016 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 A4G23_RS02320 fad98a614f636a9d199f3591d7566aec 387 Gene3D G3DSA:1.10.540.10 7 122 2.3E-7 T 10-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 A4G23_RS02320 fad98a614f636a9d199f3591d7566aec 387 SUPERFAMILY SSF47203 239 381 1.77E-17 T 10-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4G23_RS02320 fad98a614f636a9d199f3591d7566aec 387 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 241 374 3.9E-15 T 10-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4G23_RS02320 fad98a614f636a9d199f3591d7566aec 387 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 129 223 2.8E-17 T 10-11-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 A4G23_RS02320 fad98a614f636a9d199f3591d7566aec 387 Gene3D G3DSA:1.20.140.10 225 380 3.6E-22 T 10-11-2016 A4G23_RS02320 fad98a614f636a9d199f3591d7566aec 387 SUPERFAMILY SSF56645 5 242 1.7E-39 T 10-11-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 A4G23_RS02320 fad98a614f636a9d199f3591d7566aec 387 Gene3D G3DSA:2.40.110.10 129 224 2.2E-25 T 10-11-2016 A4G23_RS18785 836913cd633c07575f70903d09941c7e 122 Pfam PF02467 Transcription factor WhiB 49 97 1.1E-14 T 10-11-2016 IPR003482 Transcription factor WhiB A4G23_RS18785 836913cd633c07575f70903d09941c7e 122 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 43 111 14.691 T 10-11-2016 IPR003482 Transcription factor WhiB A4G23_RS18785 836913cd633c07575f70903d09941c7e 122 ProSitePatterns PS00354 HMG-I and HMG-Y DNA-binding domain (A+T-hook). 107 117 - T 10-11-2016 IPR000637 HMG-I/HMG-Y, DNA-binding, conserved site GO:0006355 A4G23_RS21535 62ab5899f70b614c302a6faa84589f9f 256 Pfam PF12502 Protein of unknown function (DUF3710) 49 222 2.4E-61 T 10-11-2016 IPR022183 Protein of unknown function DUF3710 A4G23_RS24290 18eaf69df9e94e04300feaa8c67cb8fe 445 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 113 189 1.8E-6 T 10-11-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A4G23_RS24290 18eaf69df9e94e04300feaa8c67cb8fe 445 SUPERFAMILY SSF50129 49 230 2.43E-28 T 10-11-2016 IPR011032 GroES-like A4G23_RS24290 18eaf69df9e94e04300feaa8c67cb8fe 445 SMART SM00829 49 415 3.5E-11 T 10-11-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A4G23_RS24290 18eaf69df9e94e04300feaa8c67cb8fe 445 Gene3D G3DSA:3.90.180.10 43 231 2.5E-30 T 10-11-2016 IPR011032 GroES-like A4G23_RS24290 18eaf69df9e94e04300feaa8c67cb8fe 445 Gene3D G3DSA:3.40.50.720 232 364 3.6E-23 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS24290 18eaf69df9e94e04300feaa8c67cb8fe 445 TIGRFAM TIGR01751 crot-CoA-red: crotonyl-CoA carboxylase/reductase 31 428 5.4E-192 T 10-11-2016 IPR010085 Crotonyl-CoA reductase GO:0043880 KEGG: 00650+1.3.1.86 A4G23_RS24290 18eaf69df9e94e04300feaa8c67cb8fe 445 Pfam PF00107 Zinc-binding dehydrogenase 236 380 3.5E-38 T 10-11-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A4G23_RS24290 18eaf69df9e94e04300feaa8c67cb8fe 445 SUPERFAMILY SSF51735 198 391 6.91E-37 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS03690 d80b4797d088c79c222239eb681681a7 833 Gene3D G3DSA:3.10.20.30 492 554 4.3E-23 T 10-11-2016 IPR012675 Beta-grasp domain A4G23_RS03690 d80b4797d088c79c222239eb681681a7 833 SUPERFAMILY SSF81271 480 552 3.71E-21 T 10-11-2016 IPR012676 TGS-like KEGG: 00970+6.1.1.3 A4G23_RS03690 d80b4797d088c79c222239eb681681a7 833 SUPERFAMILY SSF55021 749 830 1.58E-15 T 10-11-2016 A4G23_RS03690 d80b4797d088c79c222239eb681681a7 833 SMART SM00471 135 245 9.7E-13 T 10-11-2016 IPR003607 HD/PDEase domain A4G23_RS03690 d80b4797d088c79c222239eb681681a7 833 Pfam PF04607 Region found in RelA / SpoT proteins 327 436 4.1E-37 T 10-11-2016 IPR007685 RelA/SpoT GO:0015969 A4G23_RS03690 d80b4797d088c79c222239eb681681a7 833 Pfam PF13328 HD domain 120 267 1.2E-51 T 10-11-2016 IPR003607 HD/PDEase domain A4G23_RS03690 d80b4797d088c79c222239eb681681a7 833 SUPERFAMILY SSF81301 272 497 1.8E-63 T 10-11-2016 A4G23_RS03690 d80b4797d088c79c222239eb681681a7 833 SMART SM00954 327 437 2.2E-64 T 10-11-2016 IPR007685 RelA/SpoT GO:0015969 A4G23_RS03690 d80b4797d088c79c222239eb681681a7 833 SUPERFAMILY SSF109604 109 282 1.07E-70 T 10-11-2016 A4G23_RS03690 d80b4797d088c79c222239eb681681a7 833 Pfam PF02824 TGS domain 493 552 1.2E-21 T 10-11-2016 IPR004095 TGS KEGG: 00970+6.1.1.3 A4G23_RS03690 d80b4797d088c79c222239eb681681a7 833 Gene3D G3DSA:3.30.460.10 270 416 5.0E-49 T 10-11-2016 A4G23_RS03690 d80b4797d088c79c222239eb681681a7 833 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 120 826 2.4E-260 T 10-11-2016 IPR004811 RelA/SpoT family GO:0015969 A4G23_RS03690 d80b4797d088c79c222239eb681681a7 833 Pfam PF13291 ACT domain 750 826 3.9E-17 T 10-11-2016 IPR002912 ACT domain GO:0008152|GO:0016597 A4G23_RS03690 d80b4797d088c79c222239eb681681a7 833 Gene3D G3DSA:3.30.70.260 752 824 5.6E-15 T 10-11-2016 A4G23_RS02685 4c4972cdd61e0120c6222796266555b9 135 Gene3D G3DSA:3.40.960.10 8 124 1.1E-43 T 10-11-2016 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 A4G23_RS02685 4c4972cdd61e0120c6222796266555b9 135 TIGRFAM TIGR00632 vsr: DNA mismatch endonuclease Vsr 2 107 4.4E-37 T 10-11-2016 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 A4G23_RS02685 4c4972cdd61e0120c6222796266555b9 135 SUPERFAMILY SSF52980 1 114 5.2E-36 T 10-11-2016 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A4G23_RS02685 4c4972cdd61e0120c6222796266555b9 135 Pfam PF03852 DNA mismatch endonuclease Vsr 1 60 6.5E-17 T 10-11-2016 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 A4G23_RS11240 7a210488537a7e70cca20e5d11c883be 1042 PRINTS PR00364 Disease resistance protein signature 328 343 6.0E-8 T 10-11-2016 A4G23_RS11240 7a210488537a7e70cca20e5d11c883be 1042 PRINTS PR00364 Disease resistance protein signature 492 506 6.0E-8 T 10-11-2016 A4G23_RS11240 7a210488537a7e70cca20e5d11c883be 1042 PRINTS PR00364 Disease resistance protein signature 407 421 6.0E-8 T 10-11-2016 A4G23_RS11240 7a210488537a7e70cca20e5d11c883be 1042 SUPERFAMILY SSF48452 883 1021 2.53E-12 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS11240 7a210488537a7e70cca20e5d11c883be 1042 Gene3D G3DSA:1.25.40.10 700 809 8.8E-6 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS11240 7a210488537a7e70cca20e5d11c883be 1042 Gene3D G3DSA:1.25.40.10 810 1022 1.0E-19 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS11240 7a210488537a7e70cca20e5d11c883be 1042 Pfam PF03704 Bacterial transcriptional activator domain 18 159 2.8E-34 T 10-11-2016 IPR005158 Bacterial transcriptional activator domain A4G23_RS11240 7a210488537a7e70cca20e5d11c883be 1042 SUPERFAMILY SSF52540 325 560 5.33E-26 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS11240 7a210488537a7e70cca20e5d11c883be 1042 SMART SM00028 920 953 37.0 T 10-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 A4G23_RS11240 7a210488537a7e70cca20e5d11c883be 1042 SMART SM00028 760 793 86.0 T 10-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 A4G23_RS11240 7a210488537a7e70cca20e5d11c883be 1042 SMART SM00028 800 833 2.0 T 10-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 A4G23_RS11240 7a210488537a7e70cca20e5d11c883be 1042 SMART SM00028 880 913 380.0 T 10-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 A4G23_RS11240 7a210488537a7e70cca20e5d11c883be 1042 SMART SM00028 960 993 29.0 T 10-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 A4G23_RS11240 7a210488537a7e70cca20e5d11c883be 1042 SMART SM00028 840 873 260.0 T 10-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 A4G23_RS11240 7a210488537a7e70cca20e5d11c883be 1042 Gene3D G3DSA:3.40.50.300 327 420 4.1E-4 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS11240 7a210488537a7e70cca20e5d11c883be 1042 SUPERFAMILY SSF48452 13 183 3.8E-27 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS11240 7a210488537a7e70cca20e5d11c883be 1042 SUPERFAMILY SSF48452 704 862 5.48E-15 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS11240 7a210488537a7e70cca20e5d11c883be 1042 SMART SM01043 18 159 2.0E-38 T 10-11-2016 IPR005158 Bacterial transcriptional activator domain A4G23_RS11240 7a210488537a7e70cca20e5d11c883be 1042 Pfam PF00931 NB-ARC domain 326 557 2.2E-9 T 10-11-2016 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6803207 A4G23_RS26065 0c2e08f30326e11e0050ff34c816a2f7 198 PRINTS PR00449 Transforming protein P21 ras signature 15 36 3.8E-5 T 10-11-2016 A4G23_RS26065 0c2e08f30326e11e0050ff34c816a2f7 198 PRINTS PR00449 Transforming protein P21 ras signature 74 96 3.8E-5 T 10-11-2016 A4G23_RS26065 0c2e08f30326e11e0050ff34c816a2f7 198 Gene3D G3DSA:3.40.50.300 13 118 5.7E-13 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS26065 0c2e08f30326e11e0050ff34c816a2f7 198 SUPERFAMILY SSF52540 14 190 3.5E-20 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS26065 0c2e08f30326e11e0050ff34c816a2f7 198 Pfam PF03029 Conserved hypothetical ATP binding protein 19 150 3.8E-22 T 10-11-2016 IPR004130 GPN-loop GTPase A4G23_RS06785 a3b204c7b79315e336ff9ccd4a0ae349 306 SUPERFAMILY SSF53474 33 296 1.88E-38 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS06785 a3b204c7b79315e336ff9ccd4a0ae349 306 Pfam PF12697 Alpha/beta hydrolase family 64 280 6.3E-20 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS06785 a3b204c7b79315e336ff9ccd4a0ae349 306 Gene3D G3DSA:3.40.50.1820 32 296 1.5E-46 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS04690 51af512021a05e07a3310d11c4f2888b 318 SMART SM00382 31 234 7.3E-9 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS04690 51af512021a05e07a3310d11c4f2888b 318 SUPERFAMILY SSF52540 9 225 8.45E-57 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS04690 51af512021a05e07a3310d11c4f2888b 318 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS04690 51af512021a05e07a3310d11c4f2888b 318 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 14 306 1.5E-102 T 10-11-2016 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 A4G23_RS04690 51af512021a05e07a3310d11c4f2888b 318 Gene3D G3DSA:3.40.50.300 6 223 4.0E-65 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS04690 51af512021a05e07a3310d11c4f2888b 318 Pfam PF00005 ABC transporter 22 161 1.1E-26 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS15590 a6c4e35f27723f8aeb01bfb2954e2c66 338 SUPERFAMILY SSF51735 3 318 6.93E-36 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS15590 a6c4e35f27723f8aeb01bfb2954e2c66 338 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 237 1.4E-15 T 10-11-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 A4G23_RS15590 a6c4e35f27723f8aeb01bfb2954e2c66 338 Gene3D G3DSA:3.40.50.720 4 317 8.9E-27 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS00820 63153d83faa370013e7e7f58e6c10432 325 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 4.2E-6 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS00820 63153d83faa370013e7e7f58e6c10432 325 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 4.2E-6 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS00820 63153d83faa370013e7e7f58e6c10432 325 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 4.2E-6 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS00820 63153d83faa370013e7e7f58e6c10432 325 SUPERFAMILY SSF46785 3 113 1.54E-21 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS00820 63153d83faa370013e7e7f58e6c10432 325 Gene3D G3DSA:1.10.10.10 3 81 9.9E-23 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS00820 63153d83faa370013e7e7f58e6c10432 325 Gene3D G3DSA:3.40.190.10 92 180 2.7E-11 T 10-11-2016 A4G23_RS00820 63153d83faa370013e7e7f58e6c10432 325 Gene3D G3DSA:3.40.190.10 181 266 9.3E-19 T 10-11-2016 A4G23_RS00820 63153d83faa370013e7e7f58e6c10432 325 Pfam PF03466 LysR substrate binding domain 91 292 1.4E-30 T 10-11-2016 IPR005119 LysR, substrate-binding A4G23_RS00820 63153d83faa370013e7e7f58e6c10432 325 SUPERFAMILY SSF53850 92 299 5.19E-25 T 10-11-2016 A4G23_RS00820 63153d83faa370013e7e7f58e6c10432 325 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 1.4E-18 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS16700 0e597c55d54c088d02f2c363b8949acf 151 ProSitePatterns PS00475 Ribosomal protein L15 signature. 114 144 - T 10-11-2016 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS16700 0e597c55d54c088d02f2c363b8949acf 151 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 8 147 1.7E-45 T 10-11-2016 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS16700 0e597c55d54c088d02f2c363b8949acf 151 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 9 150 18.839 T 10-11-2016 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 A4G23_RS16700 0e597c55d54c088d02f2c363b8949acf 151 Gene3D G3DSA:3.100.10.10 37 150 3.7E-32 T 10-11-2016 A4G23_RS16700 0e597c55d54c088d02f2c363b8949acf 151 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 32 148 2.9E-33 T 10-11-2016 IPR021131 Ribosomal protein L18e/L15P A4G23_RS16700 0e597c55d54c088d02f2c363b8949acf 151 SUPERFAMILY SSF52080 10 149 3.01E-40 T 10-11-2016 IPR021131 Ribosomal protein L18e/L15P A4G23_RS20280 f3573110443c5bcf211990870493892c 494 SUPERFAMILY SSF52374 9 322 2.23E-103 T 10-11-2016 A4G23_RS20280 f3573110443c5bcf211990870493892c 494 Gene3D G3DSA:1.10.1160.10 256 337 1.1E-28 T 10-11-2016 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 A4G23_RS20280 f3573110443c5bcf211990870493892c 494 Hamap MF_00022_B Glutamate--tRNA ligase [gltX]. 9 489 31.863 T 10-11-2016 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 A4G23_RS20280 f3573110443c5bcf211990870493892c 494 Gene3D G3DSA:3.40.50.620 199 253 1.0E-43 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS20280 f3573110443c5bcf211990870493892c 494 Gene3D G3DSA:3.40.50.620 9 73 1.0E-43 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS20280 f3573110443c5bcf211990870493892c 494 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 9 487 4.4E-139 T 10-11-2016 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 A4G23_RS20280 f3573110443c5bcf211990870493892c 494 Gene3D G3DSA:1.10.10.350 394 489 1.6E-21 T 10-11-2016 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 A4G23_RS20280 f3573110443c5bcf211990870493892c 494 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 9 326 2.8E-90 T 10-11-2016 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 A4G23_RS20280 f3573110443c5bcf211990870493892c 494 PRINTS PR00987 Glutamyl-tRNA synthetase signature 197 207 2.9E-22 T 10-11-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 A4G23_RS20280 f3573110443c5bcf211990870493892c 494 PRINTS PR00987 Glutamyl-tRNA synthetase signature 41 54 2.9E-22 T 10-11-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 A4G23_RS20280 f3573110443c5bcf211990870493892c 494 PRINTS PR00987 Glutamyl-tRNA synthetase signature 12 24 2.9E-22 T 10-11-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 A4G23_RS20280 f3573110443c5bcf211990870493892c 494 PRINTS PR00987 Glutamyl-tRNA synthetase signature 26 37 2.9E-22 T 10-11-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 A4G23_RS20280 f3573110443c5bcf211990870493892c 494 PRINTS PR00987 Glutamyl-tRNA synthetase signature 213 221 2.9E-22 T 10-11-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 A4G23_RS20280 f3573110443c5bcf211990870493892c 494 SUPERFAMILY SSF48163 323 489 9.81E-34 T 10-11-2016 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 A4G23_RS20280 f3573110443c5bcf211990870493892c 494 Gene3D G3DSA:3.90.800.10 74 197 1.3E-39 T 10-11-2016 A4G23_RS20510 2c56ac2f02b579826e930a6df3e6bc42 226 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 3 165 7.6E-43 T 10-11-2016 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 A4G23_RS20510 2c56ac2f02b579826e930a6df3e6bc42 226 SUPERFAMILY SSF50447 3 85 2.4E-18 T 10-11-2016 IPR009000 Translation protein, beta-barrel domain A4G23_RS20510 2c56ac2f02b579826e930a6df3e6bc42 226 Gene3D G3DSA:2.30.30.240 96 166 5.5E-18 T 10-11-2016 A4G23_RS20510 2c56ac2f02b579826e930a6df3e6bc42 226 Pfam PF01782 RimM N-terminal domain 5 83 6.3E-23 T 10-11-2016 IPR002676 RimM protein GO:0006364 A4G23_RS20510 2c56ac2f02b579826e930a6df3e6bc42 226 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 2 166 22.888 T 10-11-2016 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 A4G23_RS20510 2c56ac2f02b579826e930a6df3e6bc42 226 Gene3D G3DSA:2.40.30.60 3 83 1.1E-21 T 10-11-2016 IPR002676 RimM protein GO:0006364 A4G23_RS20510 2c56ac2f02b579826e930a6df3e6bc42 226 Pfam PF05239 PRC-barrel domain 93 165 1.0E-7 T 10-11-2016 IPR027275 PRC-barrel domain A4G23_RS20510 2c56ac2f02b579826e930a6df3e6bc42 226 SUPERFAMILY SSF50346 96 166 4.71E-16 T 10-11-2016 IPR011033 PRC-barrel-like A4G23_RS02845 72d97d7b895c952355d5ca4af3c82254 399 Pfam PF02653 Branched-chain amino acid transport system / permease component 54 383 2.9E-35 T 10-11-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 A4G23_RS20780 080be5d0f0a3160c8bfde4816865c626 103 SUPERFAMILY SSF56281 2 93 3.38E-5 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS20780 080be5d0f0a3160c8bfde4816865c626 103 Gene3D G3DSA:3.60.15.10 1 90 4.6E-12 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS15205 d55adef685b060b66297d4aab42c0ec2 167 Pfam PF13581 Histidine kinase-like ATPase domain 32 144 1.1E-12 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS15205 d55adef685b060b66297d4aab42c0ec2 167 SUPERFAMILY SSF55874 49 149 1.24E-8 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS14245 a07cc67545778ec951574c51b3548a21 278 SUPERFAMILY SSF103481 184 277 6.54E-10 T 10-11-2016 A4G23_RS14245 a07cc67545778ec951574c51b3548a21 278 Pfam PF00892 EamA-like transporter family 146 275 1.1E-7 T 10-11-2016 IPR000620 EamA domain GO:0016020|GO:0016021 A4G23_RS14245 a07cc67545778ec951574c51b3548a21 278 SUPERFAMILY SSF103481 41 135 4.58E-6 T 10-11-2016 A4G23_RS05015 8609dbe56fed2b1f11a4e46577c578d2 203 Gene3D G3DSA:3.10.300.10 4 195 5.7E-67 T 10-11-2016 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 A4G23_RS05015 8609dbe56fed2b1f11a4e46577c578d2 203 Hamap MF_00527 Putative 3-methyladenine DNA glycosylase. 3 189 30.589 T 10-11-2016 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 A4G23_RS05015 8609dbe56fed2b1f11a4e46577c578d2 203 SUPERFAMILY SSF50486 2 195 3.61E-59 T 10-11-2016 IPR011034 Formyl transferase, C-terminal-like GO:0003824 A4G23_RS05015 8609dbe56fed2b1f11a4e46577c578d2 203 Pfam PF02245 Methylpurine-DNA glycosylase (MPG) 6 186 4.6E-64 T 10-11-2016 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 A4G23_RS05015 8609dbe56fed2b1f11a4e46577c578d2 203 TIGRFAM TIGR00567 3mg: DNA-3-methyladenine glycosylase 1 189 2.1E-57 T 10-11-2016 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 A4G23_RS01170 f3ed803dc957930cccadecebe116c8ef 306 Pfam PF01380 SIS domain 156 275 3.1E-8 T 10-11-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 A4G23_RS01170 f3ed803dc957930cccadecebe116c8ef 306 SUPERFAMILY SSF53697 117 301 4.89E-12 T 10-11-2016 A4G23_RS01170 f3ed803dc957930cccadecebe116c8ef 306 Gene3D G3DSA:3.40.50.10490 88 99 1.8E-10 T 10-11-2016 A4G23_RS01170 f3ed803dc957930cccadecebe116c8ef 306 Gene3D G3DSA:3.40.50.10490 131 265 1.8E-10 T 10-11-2016 A4G23_RS01170 f3ed803dc957930cccadecebe116c8ef 306 Pfam PF01418 Helix-turn-helix domain, rpiR family 38 97 9.8E-15 T 10-11-2016 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 A4G23_RS01170 f3ed803dc957930cccadecebe116c8ef 306 Gene3D G3DSA:1.10.10.10 38 87 2.2E-21 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS01170 f3ed803dc957930cccadecebe116c8ef 306 SUPERFAMILY SSF46689 38 97 3.23E-16 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS24130 13de1548fd0044325ce5e9b2ddf06a20 249 SUPERFAMILY SSF53335 71 207 1.59E-16 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS24130 13de1548fd0044325ce5e9b2ddf06a20 249 Gene3D G3DSA:3.40.50.150 72 242 5.0E-24 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS19465 8fad43414d0fd07833cdf9d927006d8a 412 Pfam PF05746 DALR anticodon binding domain 293 412 2.7E-22 T 10-11-2016 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 A4G23_RS19465 8fad43414d0fd07833cdf9d927006d8a 412 SUPERFAMILY SSF55190 15 99 1.29E-15 T 10-11-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 A4G23_RS19465 8fad43414d0fd07833cdf9d927006d8a 412 SUPERFAMILY SSF47323 287 412 7.85E-21 T 10-11-2016 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4G23_RS19465 8fad43414d0fd07833cdf9d927006d8a 412 Gene3D G3DSA:1.10.730.10 287 412 1.4E-26 T 10-11-2016 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4G23_RS19465 8fad43414d0fd07833cdf9d927006d8a 412 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 22 93 4.6E-14 T 10-11-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 A4G23_RS19465 8fad43414d0fd07833cdf9d927006d8a 412 SMART SM00836 293 412 3.4E-28 T 10-11-2016 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 A4G23_RS19465 8fad43414d0fd07833cdf9d927006d8a 412 SMART SM01016 4 93 7.8E-23 T 10-11-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 A4G23_RS19465 8fad43414d0fd07833cdf9d927006d8a 412 Gene3D G3DSA:3.30.1360.70 4 99 9.9E-21 T 10-11-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 A4G23_RS07030 f460fefe9223b45e870b353b4be5a6a8 340 SUPERFAMILY SSF55347 142 305 9.97E-43 T 10-11-2016 A4G23_RS07030 f460fefe9223b45e870b353b4be5a6a8 340 SUPERFAMILY SSF51735 12 169 1.53E-50 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS07030 f460fefe9223b45e870b353b4be5a6a8 340 Gene3D G3DSA:3.30.360.10 159 340 3.6E-53 T 10-11-2016 A4G23_RS07030 f460fefe9223b45e870b353b4be5a6a8 340 Gene3D G3DSA:3.40.50.720 14 158 5.7E-48 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS07030 f460fefe9223b45e870b353b4be5a6a8 340 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 150 213 7.1E-6 T 10-11-2016 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 A4G23_RS07030 f460fefe9223b45e870b353b4be5a6a8 340 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 18 134 1.8E-23 T 10-11-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 A4G23_RS04005 13f594a71cf39c96b426d7bf91dde6b5 383 SUPERFAMILY SSF56266 7 379 1.44E-126 T 10-11-2016 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A4G23_RS04005 13f594a71cf39c96b426d7bf91dde6b5 383 Pfam PF01960 ArgJ family 11 383 1.5E-127 T 10-11-2016 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A4G23_RS04005 13f594a71cf39c96b426d7bf91dde6b5 383 Gene3D G3DSA:3.60.70.12 2 259 7.0E-94 T 10-11-2016 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A4G23_RS04005 13f594a71cf39c96b426d7bf91dde6b5 383 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 2 382 2.3E-103 T 10-11-2016 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A4G23_RS04005 13f594a71cf39c96b426d7bf91dde6b5 383 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 383 133.085 T 10-11-2016 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A4G23_RS04005 13f594a71cf39c96b426d7bf91dde6b5 383 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 20 381 2.0E-171 T 10-11-2016 A4G23_RS17995 d8c032cb1719a56d7c965dd5820cb09f 387 Gene3D G3DSA:3.40.50.1580 6 240 1.5E-44 T 10-11-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A4G23_RS17995 d8c032cb1719a56d7c965dd5820cb09f 387 Pfam PF01048 Phosphorylase superfamily 6 241 6.2E-31 T 10-11-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A4G23_RS17995 d8c032cb1719a56d7c965dd5820cb09f 387 SUPERFAMILY SSF53167 6 248 4.45E-41 T 10-11-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A4G23_RS01620 0527dc554db2f41d47ac586ebec890cc 147 Pfam PF11292 Protein of unknown function (DUF3093) 4 142 3.0E-34 T 10-11-2016 IPR021443 Protein of unknown function DUF3093 A4G23_RS23310 b504bc040a2eb1e5a2760d1d2914c8df 140 Pfam PF13581 Histidine kinase-like ATPase domain 23 130 3.9E-9 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS23310 b504bc040a2eb1e5a2760d1d2914c8df 140 SUPERFAMILY SSF55874 52 121 2.48E-7 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS16250 287036a5f449f968ee6201a4abf251b5 231 Gene3D G3DSA:2.60.120.590 14 214 1.1E-52 T 10-11-2016 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like A4G23_RS16250 287036a5f449f968ee6201a4abf251b5 231 Pfam PF13532 2OG-Fe(II) oxygenase superfamily 18 213 7.9E-50 T 10-11-2016 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like A4G23_RS16250 287036a5f449f968ee6201a4abf251b5 231 SUPERFAMILY SSF51197 16 213 3.71E-46 T 10-11-2016 A4G23_RS11565 e937f230829987c9ceed7c9e264643bf 244 Gene3D G3DSA:3.90.226.10 3 177 1.5E-46 T 10-11-2016 IPR029045 ClpP/crotonase-like domain A4G23_RS11565 e937f230829987c9ceed7c9e264643bf 244 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 242 1.2E-48 T 10-11-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 A4G23_RS11565 e937f230829987c9ceed7c9e264643bf 244 Gene3D G3DSA:1.10.12.10 188 242 2.9E-12 T 10-11-2016 IPR014748 Crontonase, C-terminal A4G23_RS11565 e937f230829987c9ceed7c9e264643bf 244 SUPERFAMILY SSF52096 2 242 3.79E-63 T 10-11-2016 IPR029045 ClpP/crotonase-like domain A4G23_RS11565 e937f230829987c9ceed7c9e264643bf 244 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 89 109 - T 10-11-2016 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 A4G23_RS24340 be49a128e7759021164d3203bff136de 391 Pfam PF00155 Aminotransferase class I and II 29 382 2.1E-58 T 10-11-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4G23_RS24340 be49a128e7759021164d3203bff136de 391 SUPERFAMILY SSF53383 5 383 1.28E-90 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS24340 be49a128e7759021164d3203bff136de 391 PRINTS PR00799 Aspartate aminotransferase signature 196 208 3.2E-27 T 10-11-2016 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 A4G23_RS24340 be49a128e7759021164d3203bff136de 391 PRINTS PR00799 Aspartate aminotransferase signature 165 184 3.2E-27 T 10-11-2016 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 A4G23_RS24340 be49a128e7759021164d3203bff136de 391 PRINTS PR00799 Aspartate aminotransferase signature 331 349 3.2E-27 T 10-11-2016 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 A4G23_RS24340 be49a128e7759021164d3203bff136de 391 PRINTS PR00799 Aspartate aminotransferase signature 263 288 3.2E-27 T 10-11-2016 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 A4G23_RS24340 be49a128e7759021164d3203bff136de 391 Gene3D G3DSA:3.40.640.10 45 305 5.7E-78 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS04795 6140e74676bd75ad5896a4eb2349f69e 427 SUPERFAMILY SSF53756 7 384 5.83E-68 T 10-11-2016 A4G23_RS04795 6140e74676bd75ad5896a4eb2349f69e 427 Pfam PF13439 Glycosyltransferase Family 4 13 191 4.5E-9 T 10-11-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A4G23_RS04795 6140e74676bd75ad5896a4eb2349f69e 427 Pfam PF00534 Glycosyl transferases group 1 198 359 9.0E-35 T 10-11-2016 IPR001296 Glycosyl transferase, family 1 A4G23_RS04795 6140e74676bd75ad5896a4eb2349f69e 427 Gene3D G3DSA:3.40.50.2000 198 361 2.5E-25 T 10-11-2016 A4G23_RS06790 651dd3847ef9d6d0535248c1d92adcf9 167 Gene3D G3DSA:1.10.10.10 4 139 1.8E-21 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS06790 651dd3847ef9d6d0535248c1d92adcf9 167 SMART SM00347 27 131 3.2E-6 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS06790 651dd3847ef9d6d0535248c1d92adcf9 167 SUPERFAMILY SSF46785 8 139 2.54E-17 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS06790 651dd3847ef9d6d0535248c1d92adcf9 167 Pfam PF12802 MarR family 33 95 1.7E-8 T 10-11-2016 A4G23_RS22900 adf6ffc62f22e58e2abca649bceb5757 131 Gene3D G3DSA:3.40.50.1010 69 119 1.1E-5 T 10-11-2016 IPR029060 PIN domain-like A4G23_RS20870 2e1868d243956f5b34dbb454ccc8e799 307 Pfam PF04655 Aminoglycoside/hydroxyurea antibiotic resistance kinase 47 289 3.4E-57 T 10-11-2016 IPR006748 Aminoglycoside/hydroxyurea antibiotic resistance kinase GO:0006468|GO:0016773|GO:0019748 A4G23_RS20870 2e1868d243956f5b34dbb454ccc8e799 307 SUPERFAMILY SSF56112 38 288 5.1E-14 T 10-11-2016 IPR011009 Protein kinase-like domain A4G23_RS01075 80252df6a0393216df54793672091061 210 Pfam PF13580 SIS domain 4 133 1.4E-26 T 10-11-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 A4G23_RS01075 80252df6a0393216df54793672091061 210 Gene3D G3DSA:3.40.50.10490 3 175 2.7E-50 T 10-11-2016 A4G23_RS01075 80252df6a0393216df54793672091061 210 SUPERFAMILY SSF53697 3 174 9.1E-45 T 10-11-2016 A4G23_RS21715 a889855f3a0a2dce0aa38936b1f725a0 181 Pfam PF13359 DDE superfamily endonuclease 98 178 1.1E-13 T 10-11-2016 IPR027806 Harbinger transposase-derived nuclease domain A4G23_RS21715 a889855f3a0a2dce0aa38936b1f725a0 181 Pfam PF13613 Helix-turn-helix of DDE superfamily endonuclease 31 82 2.0E-15 T 10-11-2016 IPR027805 Transposase, Helix-turn-helix domain A4G23_RS13915 3f3d47c838247c47ec890b126fbbaa6c 102 SMART SM00862 24 98 2.8E-28 T 10-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4G23_RS13915 3f3d47c838247c47ec890b126fbbaa6c 102 Pfam PF00486 Transcriptional regulatory protein, C terminal 24 97 4.2E-26 T 10-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4G23_RS13915 3f3d47c838247c47ec890b126fbbaa6c 102 Gene3D G3DSA:1.10.10.10 2 101 4.5E-36 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS13915 3f3d47c838247c47ec890b126fbbaa6c 102 SUPERFAMILY SSF46894 3 99 7.65E-30 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS06375 3285cc6c848cb05977c9f0cb872ea2d1 675 Gene3D G3DSA:1.10.510.10 85 271 9.4E-49 T 10-11-2016 A4G23_RS06375 3285cc6c848cb05977c9f0cb872ea2d1 675 Pfam PF03793 PASTA domain 547 609 1.3E-11 T 10-11-2016 IPR005543 PASTA domain A4G23_RS06375 3285cc6c848cb05977c9f0cb872ea2d1 675 Pfam PF03793 PASTA domain 479 541 3.2E-11 T 10-11-2016 IPR005543 PASTA domain A4G23_RS06375 3285cc6c848cb05977c9f0cb872ea2d1 675 Pfam PF03793 PASTA domain 614 672 1.4E-10 T 10-11-2016 IPR005543 PASTA domain A4G23_RS06375 3285cc6c848cb05977c9f0cb872ea2d1 675 Pfam PF03793 PASTA domain 416 473 2.5E-7 T 10-11-2016 IPR005543 PASTA domain A4G23_RS06375 3285cc6c848cb05977c9f0cb872ea2d1 675 Pfam PF00069 Protein kinase domain 21 231 4.2E-46 T 10-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4G23_RS06375 3285cc6c848cb05977c9f0cb872ea2d1 675 SMART SM00740 543 609 1.8E-8 T 10-11-2016 IPR005543 PASTA domain A4G23_RS06375 3285cc6c848cb05977c9f0cb872ea2d1 675 SMART SM00740 405 474 8.8E-7 T 10-11-2016 IPR005543 PASTA domain A4G23_RS06375 3285cc6c848cb05977c9f0cb872ea2d1 675 SMART SM00740 610 674 5.1E-11 T 10-11-2016 IPR005543 PASTA domain A4G23_RS06375 3285cc6c848cb05977c9f0cb872ea2d1 675 SMART SM00740 475 542 8.9E-13 T 10-11-2016 IPR005543 PASTA domain A4G23_RS06375 3285cc6c848cb05977c9f0cb872ea2d1 675 SMART SM00220 18 275 3.1E-51 T 10-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4G23_RS06375 3285cc6c848cb05977c9f0cb872ea2d1 675 SUPERFAMILY SSF56112 9 271 4.45E-71 T 10-11-2016 IPR011009 Protein kinase-like domain A4G23_RS06375 3285cc6c848cb05977c9f0cb872ea2d1 675 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 137 149 - T 10-11-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 A4G23_RS06375 3285cc6c848cb05977c9f0cb872ea2d1 675 Gene3D G3DSA:3.30.200.20 10 84 6.5E-23 T 10-11-2016 A4G23_RS06375 3285cc6c848cb05977c9f0cb872ea2d1 675 SUPERFAMILY SSF54184 614 673 1.57E-6 T 10-11-2016 A4G23_RS22570 ee16ed753d052af66035ad8881bd099a 225 SUPERFAMILY SSF53271 2 211 7.55E-46 T 10-11-2016 IPR029057 Phosphoribosyltransferase-like A4G23_RS22570 ee16ed753d052af66035ad8881bd099a 225 Gene3D G3DSA:3.40.50.2020 2 65 2.0E-41 T 10-11-2016 IPR029057 Phosphoribosyltransferase-like A4G23_RS22570 ee16ed753d052af66035ad8881bd099a 225 Gene3D G3DSA:3.40.50.2020 101 206 2.0E-41 T 10-11-2016 IPR029057 Phosphoribosyltransferase-like A4G23_RS22570 ee16ed753d052af66035ad8881bd099a 225 Pfam PF00156 Phosphoribosyl transferase domain 8 192 2.4E-25 T 10-11-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 A4G23_RS07270 6534b750c80dc9c1ef69eae9c28beadc 549 Pfam PF09423 PhoD-like phosphatase 145 468 1.5E-14 T 10-11-2016 IPR018946 Alkaline phosphatase D-related A4G23_RS07270 6534b750c80dc9c1ef69eae9c28beadc 549 SUPERFAMILY SSF56300 302 368 4.27E-12 T 10-11-2016 IPR029052 Metallo-dependent phosphatase-like A4G23_RS07270 6534b750c80dc9c1ef69eae9c28beadc 549 SUPERFAMILY SSF56300 401 466 4.27E-12 T 10-11-2016 IPR029052 Metallo-dependent phosphatase-like A4G23_RS07270 6534b750c80dc9c1ef69eae9c28beadc 549 SUPERFAMILY SSF56300 129 228 4.27E-12 T 10-11-2016 IPR029052 Metallo-dependent phosphatase-like A4G23_RS07270 6534b750c80dc9c1ef69eae9c28beadc 549 Gene3D G3DSA:3.60.21.10 283 343 1.2E-7 T 10-11-2016 IPR029052 Metallo-dependent phosphatase-like A4G23_RS07270 6534b750c80dc9c1ef69eae9c28beadc 549 Gene3D G3DSA:3.60.21.10 118 232 1.2E-7 T 10-11-2016 IPR029052 Metallo-dependent phosphatase-like A4G23_RS20285 846a13591c4267202ffb93428ec8ba22 239 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 201 2.5E-19 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS20285 846a13591c4267202ffb93428ec8ba22 239 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 2.5E-7 T 10-11-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A4G23_RS20285 846a13591c4267202ffb93428ec8ba22 239 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 145 161 2.5E-7 T 10-11-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A4G23_RS20285 846a13591c4267202ffb93428ec8ba22 239 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 163 183 2.5E-7 T 10-11-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A4G23_RS20285 846a13591c4267202ffb93428ec8ba22 239 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 114 127 2.5E-7 T 10-11-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A4G23_RS20285 846a13591c4267202ffb93428ec8ba22 239 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 90 196 4.7E-11 T 10-11-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A4G23_RS20285 846a13591c4267202ffb93428ec8ba22 239 SUPERFAMILY SSF56784 3 227 1.95E-44 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS20285 846a13591c4267202ffb93428ec8ba22 239 Gene3D G3DSA:3.40.50.1000 1 222 1.0E-41 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS17455 003dcb9d42c860a24ae2f77a9fb637ce 340 SUPERFAMILY SSF51569 7 269 3.11E-36 T 10-11-2016 A4G23_RS17455 003dcb9d42c860a24ae2f77a9fb637ce 340 Gene3D G3DSA:3.20.20.70 7 253 3.6E-27 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS17455 003dcb9d42c860a24ae2f77a9fb637ce 340 Pfam PF00682 HMGL-like 129 255 1.5E-20 T 10-11-2016 IPR000891 Pyruvate carboxyltransferase GO:0003824 A4G23_RS00655 1393367a79eb1423dd1b5d38d4d68062 177 Gene3D G3DSA:1.10.1740.10 6 83 7.1E-14 T 10-11-2016 A4G23_RS00655 1393367a79eb1423dd1b5d38d4d68062 177 Gene3D G3DSA:1.10.10.10 108 164 2.7E-16 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS00655 1393367a79eb1423dd1b5d38d4d68062 177 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 163 4.7E-16 T 10-11-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS00655 1393367a79eb1423dd1b5d38d4d68062 177 Pfam PF08281 Sigma-70, region 4 109 159 2.6E-13 T 10-11-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS00655 1393367a79eb1423dd1b5d38d4d68062 177 SUPERFAMILY SSF88659 105 164 1.79E-12 T 10-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS00655 1393367a79eb1423dd1b5d38d4d68062 177 SUPERFAMILY SSF88946 8 93 2.94E-14 T 10-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS00655 1393367a79eb1423dd1b5d38d4d68062 177 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 7 166 7.0E-51 T 10-11-2016 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 A4G23_RS00655 1393367a79eb1423dd1b5d38d4d68062 177 Pfam PF04542 Sigma-70 region 2 15 81 2.0E-10 T 10-11-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS24860 3dfefabeaf301660ea9021fc18fac8b2 245 SUPERFAMILY SSF53448 1 237 6.31E-34 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS24860 3dfefabeaf301660ea9021fc18fac8b2 245 Pfam PF00483 Nucleotidyl transferase 3 122 2.9E-11 T 10-11-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A4G23_RS24860 3dfefabeaf301660ea9021fc18fac8b2 245 Gene3D G3DSA:3.90.550.10 2 239 3.2E-34 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS18765 6151499b82b5a7ba677de0a94a5b5699 311 ProSitePatterns PS00893 Nudix box signature. 206 227 - T 10-11-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A4G23_RS18765 6151499b82b5a7ba677de0a94a5b5699 311 Gene3D G3DSA:3.90.79.10 137 305 1.3E-51 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS18765 6151499b82b5a7ba677de0a94a5b5699 311 Pfam PF00293 NUDIX domain 174 283 1.2E-20 T 10-11-2016 IPR000086 NUDIX hydrolase domain GO:0016787 A4G23_RS18765 6151499b82b5a7ba677de0a94a5b5699 311 Pfam PF09296 NADH pyrophosphatase-like rudimentary NUDIX domain 43 137 2.0E-14 T 10-11-2016 IPR015375 NADH pyrophosphatase-like, N-terminal GO:0016787 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381 A4G23_RS18765 6151499b82b5a7ba677de0a94a5b5699 311 SUPERFAMILY SSF55811 123 305 2.3E-49 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS18765 6151499b82b5a7ba677de0a94a5b5699 311 Pfam PF09297 NADH pyrophosphatase zinc ribbon domain 140 170 1.1E-12 T 10-11-2016 IPR015376 Zinc ribbon, NADH pyrophosphatase GO:0016787|GO:0046872 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381 A4G23_RS23135 206a88f7477d698a32abfd9cbfd8ff94 268 Gene3D G3DSA:3.40.720.10 10 258 9.3E-15 T 10-11-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 A4G23_RS23135 206a88f7477d698a32abfd9cbfd8ff94 268 Pfam PF00884 Sulfatase 11 247 2.2E-7 T 10-11-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 A4G23_RS23135 206a88f7477d698a32abfd9cbfd8ff94 268 SUPERFAMILY SSF53649 9 259 4.91E-23 T 10-11-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 A4G23_RS17785 4842e9313db9b468d89b1806c330b101 556 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 225 310 3.8E-24 T 10-11-2016 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS17785 4842e9313db9b468d89b1806c330b101 556 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 148 157 - T 10-11-2016 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS17785 4842e9313db9b468d89b1806c330b101 556 Gene3D G3DSA:3.30.310.50 462 539 1.2E-18 T 10-11-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS17785 4842e9313db9b468d89b1806c330b101 556 Gene3D G3DSA:3.40.120.10 229 306 1.3E-21 T 10-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS17785 4842e9313db9b468d89b1806c330b101 556 Gene3D G3DSA:3.40.120.10 307 439 2.3E-33 T 10-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS17785 4842e9313db9b468d89b1806c330b101 556 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 52 189 2.1E-40 T 10-11-2016 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS17785 4842e9313db9b468d89b1806c330b101 556 SUPERFAMILY SSF53738 44 215 7.06E-42 T 10-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS17785 4842e9313db9b468d89b1806c330b101 556 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 325 432 1.5E-16 T 10-11-2016 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS17785 4842e9313db9b468d89b1806c330b101 556 SUPERFAMILY SSF55957 439 527 1.19E-14 T 10-11-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS17785 4842e9313db9b468d89b1806c330b101 556 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 470 535 6.6E-9 T 10-11-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS17785 4842e9313db9b468d89b1806c330b101 556 SUPERFAMILY SSF53738 302 437 1.65E-25 T 10-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS17785 4842e9313db9b468d89b1806c330b101 556 SUPERFAMILY SSF53738 209 313 6.28E-22 T 10-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS17785 4842e9313db9b468d89b1806c330b101 556 Gene3D G3DSA:3.40.120.10 25 215 2.7E-59 T 10-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4G23_RS08655 da95ce442debbe5a96b200ebc8dfda51 243 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 67 2.7E-18 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS08655 da95ce442debbe5a96b200ebc8dfda51 243 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 27 41 2.2E-6 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS08655 da95ce442debbe5a96b200ebc8dfda51 243 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 57 2.2E-6 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS08655 da95ce442debbe5a96b200ebc8dfda51 243 Gene3D G3DSA:1.10.10.10 3 70 3.7E-25 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS08655 da95ce442debbe5a96b200ebc8dfda51 243 Gene3D G3DSA:3.40.1410.10 84 227 1.6E-27 T 10-11-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain A4G23_RS08655 da95ce442debbe5a96b200ebc8dfda51 243 SMART SM00345 8 67 1.1E-18 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS08655 da95ce442debbe5a96b200ebc8dfda51 243 SUPERFAMILY SSF64288 55 231 9.89E-27 T 10-11-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain A4G23_RS08655 da95ce442debbe5a96b200ebc8dfda51 243 SMART SM00866 88 227 6.3E-14 T 10-11-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A4G23_RS08655 da95ce442debbe5a96b200ebc8dfda51 243 Pfam PF07702 UTRA domain 97 226 1.1E-22 T 10-11-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A4G23_RS08655 da95ce442debbe5a96b200ebc8dfda51 243 SUPERFAMILY SSF46785 3 70 4.39E-21 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS06165 c93d1814f6a21fed79942fa118904874 189 Gene3D G3DSA:3.40.50.1820 3 186 2.2E-24 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS06165 c93d1814f6a21fed79942fa118904874 189 Pfam PF01738 Dienelactone hydrolase family 3 187 9.1E-21 T 10-11-2016 IPR002925 Dienelactone hydrolase GO:0016787 A4G23_RS06165 c93d1814f6a21fed79942fa118904874 189 SUPERFAMILY SSF53474 3 186 2.36E-26 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS21905 1f9786b3094e5f14ce9fe2887d5f8c52 177 Pfam PF00440 Bacterial regulatory proteins, tetR family 2 45 2.3E-6 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS21905 1f9786b3094e5f14ce9fe2887d5f8c52 177 Gene3D G3DSA:1.10.10.60 1 47 7.5E-14 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS21905 1f9786b3094e5f14ce9fe2887d5f8c52 177 SUPERFAMILY SSF46689 2 63 1.03E-8 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS21905 1f9786b3094e5f14ce9fe2887d5f8c52 177 Gene3D G3DSA:1.10.357.10 48 175 2.5E-34 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS21905 1f9786b3094e5f14ce9fe2887d5f8c52 177 SUPERFAMILY SSF48498 68 174 8.9E-21 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS21905 1f9786b3094e5f14ce9fe2887d5f8c52 177 Pfam PF13305 WHG domain 74 151 2.8E-10 T 10-11-2016 IPR025996 WHG domain A4G23_RS00170 319a1d05c7380480fefa3f6cd493c86f 520 SUPERFAMILY SSF51126 36 359 9.1E-75 T 10-11-2016 IPR011050 Pectin lyase fold/virulence factor A4G23_RS00170 319a1d05c7380480fefa3f6cd493c86f 520 SMART SM00656 78 288 1.5E-18 T 10-11-2016 IPR002022 Pectate lyase/Amb allergen A4G23_RS00170 319a1d05c7380480fefa3f6cd493c86f 520 Pfam PF00544 Pectate lyase 79 282 6.2E-34 T 10-11-2016 IPR002022 Pectate lyase/Amb allergen A4G23_RS00170 319a1d05c7380480fefa3f6cd493c86f 520 Gene3D G3DSA:2.160.20.10 27 358 7.4E-82 T 10-11-2016 IPR012334 Pectin lyase fold A4G23_RS14615 2fce44d31a99dccbe759464cb1b6ab95 291 SUPERFAMILY SSF53474 7 287 1.5E-54 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS14615 2fce44d31a99dccbe759464cb1b6ab95 291 Pfam PF00561 alpha/beta hydrolase fold 26 131 4.6E-19 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS14615 2fce44d31a99dccbe759464cb1b6ab95 291 Pfam PF08386 TAP-like protein 216 272 1.5E-5 T 10-11-2016 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal A4G23_RS14615 2fce44d31a99dccbe759464cb1b6ab95 291 Gene3D G3DSA:3.40.50.1820 3 287 6.0E-61 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS04640 65137e1671abe41649b738c01bdffc27 236 SUPERFAMILY SSF46785 7 93 3.81E-16 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS04640 65137e1671abe41649b738c01bdffc27 236 Gene3D G3DSA:1.10.10.10 6 94 3.3E-19 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS04640 65137e1671abe41649b738c01bdffc27 236 Pfam PF12840 Helix-turn-helix domain 13 72 7.1E-10 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS04640 65137e1671abe41649b738c01bdffc27 236 SMART SM00418 13 92 2.1E-11 T 10-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4G23_RS09380 05d5f76540855ea3410797f0b8b01ea9 112 Pfam PF00166 Chaperonin 10 Kd subunit 10 96 5.7E-19 T 10-11-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A4G23_RS09380 05d5f76540855ea3410797f0b8b01ea9 112 Gene3D G3DSA:2.30.33.40 11 96 3.9E-19 T 10-11-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A4G23_RS09380 05d5f76540855ea3410797f0b8b01ea9 112 SUPERFAMILY SSF50129 10 97 1.89E-17 T 10-11-2016 IPR011032 GroES-like A4G23_RS09380 05d5f76540855ea3410797f0b8b01ea9 112 SMART SM00883 10 97 7.2E-25 T 10-11-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A4G23_RS09380 05d5f76540855ea3410797f0b8b01ea9 112 PRINTS PR00297 10kDa chaperonin signature 37 58 3.8E-8 T 10-11-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A4G23_RS09380 05d5f76540855ea3410797f0b8b01ea9 112 PRINTS PR00297 10kDa chaperonin signature 84 97 3.8E-8 T 10-11-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A4G23_RS09380 05d5f76540855ea3410797f0b8b01ea9 112 PRINTS PR00297 10kDa chaperonin signature 63 75 3.8E-8 T 10-11-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A4G23_RS09380 05d5f76540855ea3410797f0b8b01ea9 112 PRINTS PR00297 10kDa chaperonin signature 11 26 3.8E-8 T 10-11-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A4G23_RS25925 4f29e72c2cee729f65af4df99f6c8360 571 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 253 307 - T 10-11-2016 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS25925 4f29e72c2cee729f65af4df99f6c8360 571 Gene3D G3DSA:1.20.210.10 16 541 3.3E-197 T 10-11-2016 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS25925 4f29e72c2cee729f65af4df99f6c8360 571 SUPERFAMILY SSF81442 21 531 1.44E-177 T 10-11-2016 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS25925 4f29e72c2cee729f65af4df99f6c8360 571 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 24 529 2.4E-214 T 10-11-2016 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 A4G23_RS25925 4f29e72c2cee729f65af4df99f6c8360 571 PRINTS PR01165 Cytochrome c oxidase subunit I signature 354 372 3.5E-103 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS25925 4f29e72c2cee729f65af4df99f6c8360 571 PRINTS PR01165 Cytochrome c oxidase subunit I signature 297 312 3.5E-103 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS25925 4f29e72c2cee729f65af4df99f6c8360 571 PRINTS PR01165 Cytochrome c oxidase subunit I signature 140 152 3.5E-103 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS25925 4f29e72c2cee729f65af4df99f6c8360 571 PRINTS PR01165 Cytochrome c oxidase subunit I signature 70 93 3.5E-103 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS25925 4f29e72c2cee729f65af4df99f6c8360 571 PRINTS PR01165 Cytochrome c oxidase subunit I signature 230 251 3.5E-103 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS25925 4f29e72c2cee729f65af4df99f6c8360 571 PRINTS PR01165 Cytochrome c oxidase subunit I signature 251 272 3.5E-103 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS25925 4f29e72c2cee729f65af4df99f6c8360 571 PRINTS PR01165 Cytochrome c oxidase subunit I signature 97 121 3.5E-103 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS25925 4f29e72c2cee729f65af4df99f6c8360 571 PRINTS PR01165 Cytochrome c oxidase subunit I signature 23 48 3.5E-103 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS25925 4f29e72c2cee729f65af4df99f6c8360 571 PRINTS PR01165 Cytochrome c oxidase subunit I signature 382 401 3.5E-103 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS25925 4f29e72c2cee729f65af4df99f6c8360 571 PRINTS PR01165 Cytochrome c oxidase subunit I signature 172 190 3.5E-103 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS25925 4f29e72c2cee729f65af4df99f6c8360 571 PRINTS PR01165 Cytochrome c oxidase subunit I signature 201 220 3.5E-103 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS25925 4f29e72c2cee729f65af4df99f6c8360 571 PRINTS PR01165 Cytochrome c oxidase subunit I signature 319 340 3.5E-103 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS25925 4f29e72c2cee729f65af4df99f6c8360 571 PRINTS PR01165 Cytochrome c oxidase subunit I signature 432 453 3.5E-103 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS25925 4f29e72c2cee729f65af4df99f6c8360 571 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 32 476 1.9E-148 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS24725 1448b824236b1bbf569632d70cbd726d 234 Hamap MF_00801 Endonuclease V [nfi]. 13 227 32.694 T 10-11-2016 IPR007581 Endonuclease V GO:0004519|GO:0006281 A4G23_RS24725 1448b824236b1bbf569632d70cbd726d 234 Pfam PF04493 Endonuclease V 24 217 7.1E-64 T 10-11-2016 IPR007581 Endonuclease V GO:0004519|GO:0006281 A4G23_RS07960 4074b16d289034abfbe47fcdada294f9 88 Pfam PF01649 Ribosomal protein S20 2 83 1.9E-26 T 10-11-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS07960 4074b16d289034abfbe47fcdada294f9 88 Gene3D G3DSA:1.20.58.110 2 86 1.6E-28 T 10-11-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS07960 4074b16d289034abfbe47fcdada294f9 88 TIGRFAM TIGR00029 S20: ribosomal protein bS20 2 85 2.1E-21 T 10-11-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS07960 4074b16d289034abfbe47fcdada294f9 88 SUPERFAMILY SSF46992 3 86 7.19E-27 T 10-11-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS07960 4074b16d289034abfbe47fcdada294f9 88 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 14 68 1.0E-17 T 10-11-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS07960 4074b16d289034abfbe47fcdada294f9 88 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 16.941 T 10-11-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS08555 d64ca959d25288f503acdeedec8a5c93 149 Pfam PF00436 Single-strand binding protein family 6 85 1.1E-14 T 10-11-2016 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 A4G23_RS08555 d64ca959d25288f503acdeedec8a5c93 149 SUPERFAMILY SSF50249 5 130 1.34E-20 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS08555 d64ca959d25288f503acdeedec8a5c93 149 Gene3D G3DSA:2.40.50.140 3 120 1.1E-25 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS08555 d64ca959d25288f503acdeedec8a5c93 149 PIRSF PIRSF002070 1 146 5.1E-19 T 10-11-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 A4G23_RS07580 f1aa73e9d66fdccff0848c2be240a450 137 Gene3D G3DSA:2.20.25.10 1 43 1.3E-16 T 10-11-2016 A4G23_RS07580 f1aa73e9d66fdccff0848c2be240a450 137 Pfam PF02566 OsmC-like protein 37 134 4.9E-20 T 10-11-2016 IPR003718 OsmC/Ohr family A4G23_RS07580 f1aa73e9d66fdccff0848c2be240a450 137 SUPERFAMILY SSF82784 1 137 3.66E-39 T 10-11-2016 IPR003718 OsmC/Ohr family A4G23_RS07580 f1aa73e9d66fdccff0848c2be240a450 137 Gene3D G3DSA:3.30.300.20 44 136 3.8E-34 T 10-11-2016 IPR015946 K homology domain-like, alpha/beta A4G23_RS07580 f1aa73e9d66fdccff0848c2be240a450 137 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 5 135 1.9E-48 T 10-11-2016 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 A4G23_RS12425 b770a3c52119d0ffea4298ac33b326ed 88 Pfam PF11298 Protein of unknown function (DUF3099) 3 59 7.5E-6 T 10-11-2016 IPR021449 Protein of unknown function DUF3099 A4G23_RS01940 d77c61c311f0aa63c24fb85b4069ab0c 261 Pfam PF01012 Electron transfer flavoprotein domain 25 209 2.7E-46 T 10-11-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 A4G23_RS01940 d77c61c311f0aa63c24fb85b4069ab0c 261 PIRSF PIRSF000090 3 261 1.3E-83 T 10-11-2016 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105 A4G23_RS01940 d77c61c311f0aa63c24fb85b4069ab0c 261 SUPERFAMILY SSF52402 3 255 1.45E-71 T 10-11-2016 A4G23_RS01940 d77c61c311f0aa63c24fb85b4069ab0c 261 SMART SM00893 24 214 3.2E-58 T 10-11-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 A4G23_RS01940 d77c61c311f0aa63c24fb85b4069ab0c 261 Gene3D G3DSA:3.40.50.620 3 260 1.9E-85 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS00795 32ab93360129dd7eaf6f8ca928e04248 164 ProDom PD339375 PRECURSOR SIGNAL SCO3656 SCO2458 CGL2705 MB2629 RV2598/MT2673.1 1 164 3.0E-31 T 10-11-2016 IPR024486 Protein of unknown function DUF2617 A4G23_RS00795 32ab93360129dd7eaf6f8ca928e04248 164 Pfam PF10936 Protein of unknown function DUF2617 5 161 5.2E-51 T 10-11-2016 IPR024486 Protein of unknown function DUF2617 A4G23_RS14210 1a263f9f1985a8ab97e9d8c37ebff91b 497 Gene3D G3DSA:3.40.50.300 282 433 2.0E-40 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS14210 1a263f9f1985a8ab97e9d8c37ebff91b 497 SMART SM00490 326 407 2.9E-29 T 10-11-2016 IPR001650 Helicase, C-terminal A4G23_RS14210 1a263f9f1985a8ab97e9d8c37ebff91b 497 SUPERFAMILY SSF52540 144 424 3.46E-64 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS14210 1a263f9f1985a8ab97e9d8c37ebff91b 497 Pfam PF00271 Helicase conserved C-terminal domain 309 407 2.1E-24 T 10-11-2016 IPR001650 Helicase, C-terminal A4G23_RS14210 1a263f9f1985a8ab97e9d8c37ebff91b 497 Pfam PF00270 DEAD/DEAH box helicase 97 265 1.1E-42 T 10-11-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A4G23_RS14210 1a263f9f1985a8ab97e9d8c37ebff91b 497 SMART SM00487 92 292 2.0E-51 T 10-11-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4G23_RS14210 1a263f9f1985a8ab97e9d8c37ebff91b 497 Gene3D G3DSA:3.40.50.300 65 281 8.6E-67 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS18115 ae4b93fc39ca38578709951b5ba4d8ca 448 Gene3D G3DSA:3.40.50.300 185 407 2.1E-60 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS18115 ae4b93fc39ca38578709951b5ba4d8ca 448 Gene3D G3DSA:3.30.450.90 84 181 8.3E-38 T 10-11-2016 A4G23_RS18115 ae4b93fc39ca38578709951b5ba4d8ca 448 Pfam PF00437 Type II/IV secretion system protein 87 363 5.9E-88 T 10-11-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 A4G23_RS18115 ae4b93fc39ca38578709951b5ba4d8ca 448 SUPERFAMILY SSF52540 72 369 3.2E-58 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS24010 7807ccd466da9f555cf7c216e20a7978 131 SUPERFAMILY SSF51182 15 109 3.57E-15 T 10-11-2016 IPR011051 RmlC-like cupin domain A4G23_RS24010 7807ccd466da9f555cf7c216e20a7978 131 Pfam PF06249 Ethanolamine utilisation protein EutQ 24 102 2.3E-6 T 10-11-2016 IPR010424 Ethanolamine utilisation EutQ A4G23_RS24010 7807ccd466da9f555cf7c216e20a7978 131 Gene3D G3DSA:2.60.120.10 21 110 1.0E-13 T 10-11-2016 IPR014710 RmlC-like jelly roll fold A4G23_RS17105 8bb467e93c8b29b4eed5f148f95c796c 821 TIGRFAM TIGR01073 pcrA: ATP-dependent DNA helicase PcrA 69 819 0.0 T 10-11-2016 IPR005751 ATP-dependent DNA helicase PcrA GO:0004003|GO:0005737|GO:0006268 A4G23_RS17105 8bb467e93c8b29b4eed5f148f95c796c 821 Pfam PF13361 UvrD-like helicase C-terminal domain 349 693 3.9E-68 T 10-11-2016 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 A4G23_RS17105 8bb467e93c8b29b4eed5f148f95c796c 821 Gene3D G3DSA:3.40.50.300 252 357 2.6E-71 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS17105 8bb467e93c8b29b4eed5f148f95c796c 821 Gene3D G3DSA:3.40.50.300 69 173 2.6E-71 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS17105 8bb467e93c8b29b4eed5f148f95c796c 821 Pfam PF00580 UvrD/REP helicase N-terminal domain 73 343 1.3E-76 T 10-11-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 A4G23_RS17105 8bb467e93c8b29b4eed5f148f95c796c 821 Gene3D G3DSA:3.40.50.300 631 722 2.2E-71 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS17105 8bb467e93c8b29b4eed5f148f95c796c 821 Gene3D G3DSA:3.40.50.300 358 460 2.2E-71 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS17105 8bb467e93c8b29b4eed5f148f95c796c 821 SUPERFAMILY SSF52540 69 721 1.22E-177 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS17105 8bb467e93c8b29b4eed5f148f95c796c 821 Gene3D G3DSA:1.10.486.10 461 616 2.5E-47 T 10-11-2016 A4G23_RS17105 8bb467e93c8b29b4eed5f148f95c796c 821 Gene3D G3DSA:1.10.10.160 177 251 1.4E-24 T 10-11-2016 IPR013986 DExx box DNA helicase domain A4G23_RS21455 2557f1b195a05409352c132e0a28c0ec 243 SUPERFAMILY SSF52540 1 139 6.29E-27 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS21455 2557f1b195a05409352c132e0a28c0ec 243 SUPERFAMILY SSF57716 144 196 1.95E-8 T 10-11-2016 A4G23_RS21455 2557f1b195a05409352c132e0a28c0ec 243 Pfam PF00265 Thymidine kinase 4 191 1.7E-23 T 10-11-2016 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-73614 A4G23_RS21455 2557f1b195a05409352c132e0a28c0ec 243 Gene3D G3DSA:3.40.50.300 2 120 4.1E-5 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS21455 2557f1b195a05409352c132e0a28c0ec 243 Gene3D G3DSA:3.30.60.20 144 194 2.8E-5 T 10-11-2016 A4G23_RS16975 ea10f009eb4f6b86d684f3280a0df00d 374 SMART SM01240 14 372 8.4E-30 T 10-11-2016 A4G23_RS16975 ea10f009eb4f6b86d684f3280a0df00d 374 TIGRFAM TIGR01304 IMP_DH_rel_2: IMP dehydrogenase family protein 4 367 4.3E-194 T 10-11-2016 IPR005992 IMP dehydrogenase-related 2 GO:0016491|GO:0055114 A4G23_RS16975 ea10f009eb4f6b86d684f3280a0df00d 374 Gene3D G3DSA:3.20.20.70 13 368 2.1E-75 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS16975 ea10f009eb4f6b86d684f3280a0df00d 374 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 15 298 1.6E-43 T 10-11-2016 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 A4G23_RS16975 ea10f009eb4f6b86d684f3280a0df00d 374 SUPERFAMILY SSF51412 12 77 1.83E-69 T 10-11-2016 A4G23_RS16975 ea10f009eb4f6b86d684f3280a0df00d 374 SUPERFAMILY SSF51412 113 371 1.83E-69 T 10-11-2016 A4G23_RS00975 035fed4a9e2b09dedd92437a9205742f 494 SUPERFAMILY SSF53474 1 492 4.33E-99 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS00975 035fed4a9e2b09dedd92437a9205742f 494 Gene3D G3DSA:3.40.50.1820 1 493 7.2E-121 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS00975 035fed4a9e2b09dedd92437a9205742f 494 Pfam PF00135 Carboxylesterase family 8 468 2.4E-89 T 10-11-2016 IPR002018 Carboxylesterase, type B A4G23_RS04025 1094ffb1e6e1e594dc5e1d043ad24c5c 215 SUPERFAMILY SSF46894 143 212 3.74E-22 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS04025 1094ffb1e6e1e594dc5e1d043ad24c5c 215 Gene3D G3DSA:1.10.10.10 154 211 4.0E-27 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS04025 1094ffb1e6e1e594dc5e1d043ad24c5c 215 Pfam PF00072 Response regulator receiver domain 5 118 6.1E-25 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS04025 1094ffb1e6e1e594dc5e1d043ad24c5c 215 SUPERFAMILY SSF52172 1 133 2.85E-31 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS04025 1094ffb1e6e1e594dc5e1d043ad24c5c 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 2.6E-14 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS04025 1094ffb1e6e1e594dc5e1d043ad24c5c 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 2.6E-14 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS04025 1094ffb1e6e1e594dc5e1d043ad24c5c 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 2.6E-14 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS04025 1094ffb1e6e1e594dc5e1d043ad24c5c 215 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 209 5.6E-20 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS04025 1094ffb1e6e1e594dc5e1d043ad24c5c 215 SMART SM00421 152 209 2.5E-25 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS04025 1094ffb1e6e1e594dc5e1d043ad24c5c 215 ProSitePatterns PS00622 LuxR-type HTH domain signature. 169 196 - T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS04025 1094ffb1e6e1e594dc5e1d043ad24c5c 215 Gene3D G3DSA:3.40.50.2300 2 153 3.7E-37 T 10-11-2016 A4G23_RS04025 1094ffb1e6e1e594dc5e1d043ad24c5c 215 SMART SM00448 3 118 1.6E-27 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS27030 aa07cbec5d1701336bd6f351a4756ad5 224 Pfam PF03781 Sulfatase-modifying factor enzyme 1 3 211 9.2E-37 T 10-11-2016 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 A4G23_RS27030 aa07cbec5d1701336bd6f351a4756ad5 224 SUPERFAMILY SSF56436 1 213 1.65E-50 T 10-11-2016 IPR016187 C-type lectin fold A4G23_RS27030 aa07cbec5d1701336bd6f351a4756ad5 224 Gene3D G3DSA:3.90.1580.10 1 214 3.2E-48 T 10-11-2016 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 A4G23_RS15465 cbe6f7c1983d4af1cb4dc9d51e3e2ad1 319 ProSitePatterns PS01155 Endonuclease III family signature. 129 158 - T 10-11-2016 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 A4G23_RS15465 cbe6f7c1983d4af1cb4dc9d51e3e2ad1 319 Gene3D G3DSA:1.10.340.30 49 149 1.3E-33 T 10-11-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A4G23_RS15465 cbe6f7c1983d4af1cb4dc9d51e3e2ad1 319 SUPERFAMILY SSF48150 32 245 1.52E-59 T 10-11-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A4G23_RS15465 cbe6f7c1983d4af1cb4dc9d51e3e2ad1 319 Pfam PF00633 Helix-hairpin-helix motif 126 155 5.7E-8 T 10-11-2016 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 A4G23_RS15465 cbe6f7c1983d4af1cb4dc9d51e3e2ad1 319 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 62 176 1.1E-10 T 10-11-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A4G23_RS15465 cbe6f7c1983d4af1cb4dc9d51e3e2ad1 319 Gene3D G3DSA:1.10.1670.10 150 246 3.2E-32 T 10-11-2016 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 A4G23_RS15465 cbe6f7c1983d4af1cb4dc9d51e3e2ad1 319 SMART SM00478 66 218 7.2E-33 T 10-11-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A4G23_RS22510 3f8074f34a0a1afbd08a9ae0c5de6b1c 142 Gene3D G3DSA:3.10.180.10 8 140 3.6E-7 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS22510 3f8074f34a0a1afbd08a9ae0c5de6b1c 142 SUPERFAMILY SSF54593 8 141 1.02E-8 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS02235 f8fe2758002dd15867fdef0431ba862e 620 SUPERFAMILY SSF55874 8 205 1.06E-40 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS02235 f8fe2758002dd15867fdef0431ba862e 620 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 30 162 2.0E-9 T 10-11-2016 A4G23_RS02235 f8fe2758002dd15867fdef0431ba862e 620 SUPERFAMILY SSF54211 218 446 1.44E-38 T 10-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold A4G23_RS02235 f8fe2758002dd15867fdef0431ba862e 620 PIRSF PIRSF002583 2 611 6.3E-93 T 10-11-2016 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 A4G23_RS02235 f8fe2758002dd15867fdef0431ba862e 620 Gene3D G3DSA:3.30.565.10 7 221 2.0E-46 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS02235 f8fe2758002dd15867fdef0431ba862e 620 PRINTS PR00775 90kDa heat shock protein signature 27 49 5.6E-15 T 10-11-2016 IPR020575 Heat shock protein Hsp90, N-terminal A4G23_RS02235 f8fe2758002dd15867fdef0431ba862e 620 PRINTS PR00775 90kDa heat shock protein signature 6 26 5.6E-15 T 10-11-2016 IPR020575 Heat shock protein Hsp90, N-terminal A4G23_RS02235 f8fe2758002dd15867fdef0431ba862e 620 PRINTS PR00775 90kDa heat shock protein signature 112 134 5.6E-15 T 10-11-2016 IPR020575 Heat shock protein Hsp90, N-terminal A4G23_RS02235 f8fe2758002dd15867fdef0431ba862e 620 PRINTS PR00775 90kDa heat shock protein signature 167 184 5.6E-15 T 10-11-2016 IPR020575 Heat shock protein Hsp90, N-terminal A4G23_RS02235 f8fe2758002dd15867fdef0431ba862e 620 Pfam PF00183 Hsp90 protein 281 372 7.6E-6 T 10-11-2016 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 A4G23_RS19185 218ed46dfb4c408d8a1b52d4d506e74a 322 Pfam PF00107 Zinc-binding dehydrogenase 165 283 1.9E-17 T 10-11-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A4G23_RS19185 218ed46dfb4c408d8a1b52d4d506e74a 322 Gene3D G3DSA:3.90.180.10 15 158 2.1E-29 T 10-11-2016 IPR011032 GroES-like A4G23_RS19185 218ed46dfb4c408d8a1b52d4d506e74a 322 Gene3D G3DSA:3.40.50.720 159 267 3.7E-20 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS19185 218ed46dfb4c408d8a1b52d4d506e74a 322 SUPERFAMILY SSF50129 6 154 1.12E-30 T 10-11-2016 IPR011032 GroES-like A4G23_RS19185 218ed46dfb4c408d8a1b52d4d506e74a 322 SMART SM00829 13 318 2.0E-12 T 10-11-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A4G23_RS19185 218ed46dfb4c408d8a1b52d4d506e74a 322 SUPERFAMILY SSF51735 126 287 9.92E-37 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS03285 651842d10e00bab87afa018e6e664412 390 SUPERFAMILY SSF56645 13 249 1.57E-72 T 10-11-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 A4G23_RS03285 651842d10e00bab87afa018e6e664412 390 Gene3D G3DSA:2.40.110.10 130 225 1.2E-39 T 10-11-2016 A4G23_RS03285 651842d10e00bab87afa018e6e664412 390 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 130 224 5.8E-27 T 10-11-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 A4G23_RS03285 651842d10e00bab87afa018e6e664412 390 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 15 125 5.7E-22 T 10-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 A4G23_RS03285 651842d10e00bab87afa018e6e664412 390 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 343 362 - T 10-11-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A4G23_RS03285 651842d10e00bab87afa018e6e664412 390 Gene3D G3DSA:1.10.540.10 15 125 9.7E-28 T 10-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 A4G23_RS03285 651842d10e00bab87afa018e6e664412 390 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 236 384 4.6E-50 T 10-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4G23_RS03285 651842d10e00bab87afa018e6e664412 390 PIRSF PIRSF016578 4 389 2.1E-15 T 10-11-2016 A4G23_RS03285 651842d10e00bab87afa018e6e664412 390 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 132 144 - T 10-11-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A4G23_RS03285 651842d10e00bab87afa018e6e664412 390 Gene3D G3DSA:1.20.140.10 226 386 3.5E-71 T 10-11-2016 A4G23_RS03285 651842d10e00bab87afa018e6e664412 390 SUPERFAMILY SSF47203 234 386 4.35E-59 T 10-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4G23_RS02055 f4deb713aeb8008b2150231b3ee9111e 328 Pfam PF00296 Luciferase-like monooxygenase 14 294 6.7E-58 T 10-11-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4G23_RS02055 f4deb713aeb8008b2150231b3ee9111e 328 Gene3D G3DSA:3.20.20.30 2 326 9.2E-80 T 10-11-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4G23_RS02055 f4deb713aeb8008b2150231b3ee9111e 328 SUPERFAMILY SSF51679 8 326 1.06E-72 T 10-11-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4G23_RS10410 285c5076d19a3261fec6d1e5c19ec5f3 216 SUPERFAMILY SSF109998 32 153 3.14E-14 T 10-11-2016 IPR027304 Trigger factor/SurA domain A4G23_RS10410 285c5076d19a3261fec6d1e5c19ec5f3 216 Pfam PF13624 SurA N-terminal domain 27 149 1.1E-10 T 10-11-2016 A4G23_RS13620 7d86f9088f81e1c1f8e384a43b3df185 494 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 59 492 3.9E-168 T 10-11-2016 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 A4G23_RS13620 7d86f9088f81e1c1f8e384a43b3df185 494 Pfam PF03796 DnaB-like helicase C terminal domain 234 489 6.3E-109 T 10-11-2016 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 A4G23_RS13620 7d86f9088f81e1c1f8e384a43b3df185 494 Pfam PF00772 DnaB-like helicase N terminal domain 59 160 2.3E-36 T 10-11-2016 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 A4G23_RS13620 7d86f9088f81e1c1f8e384a43b3df185 494 SMART SM00382 251 450 6.3E-4 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS13620 7d86f9088f81e1c1f8e384a43b3df185 494 SUPERFAMILY SSF52540 232 483 4.41E-52 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS13620 7d86f9088f81e1c1f8e384a43b3df185 494 Gene3D G3DSA:3.40.50.300 219 493 3.6E-120 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS13620 7d86f9088f81e1c1f8e384a43b3df185 494 Gene3D G3DSA:1.10.860.10 59 161 1.4E-41 T 10-11-2016 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal A4G23_RS13620 7d86f9088f81e1c1f8e384a43b3df185 494 SUPERFAMILY SSF48024 57 168 1.96E-38 T 10-11-2016 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 A4G23_RS18905 718b66cfbb48e826deee32f2732e8a54 336 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 36 334 26.639 T 10-11-2016 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 A4G23_RS18905 718b66cfbb48e826deee32f2732e8a54 336 Pfam PF03193 Protein of unknown function, DUF258 96 271 8.3E-42 T 10-11-2016 IPR010914 RsgA type GTPase domain GO:0003924|GO:0005525 A4G23_RS18905 718b66cfbb48e826deee32f2732e8a54 336 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 71 325 1.4E-39 T 10-11-2016 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 A4G23_RS18905 718b66cfbb48e826deee32f2732e8a54 336 SUPERFAMILY SSF52540 113 332 7.57E-41 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS18905 718b66cfbb48e826deee32f2732e8a54 336 Gene3D G3DSA:1.10.40.50 273 333 2.0E-13 T 10-11-2016 A4G23_RS18905 718b66cfbb48e826deee32f2732e8a54 336 Gene3D G3DSA:3.40.50.300 113 271 4.0E-48 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS17485 3d21899df31bbd8aa30a9dc978f8a369 117 Pfam PF07883 Cupin domain 44 109 3.5E-14 T 10-11-2016 IPR013096 Cupin 2, conserved barrel A4G23_RS17485 3d21899df31bbd8aa30a9dc978f8a369 117 SUPERFAMILY SSF51182 35 111 1.47E-17 T 10-11-2016 IPR011051 RmlC-like cupin domain A4G23_RS17485 3d21899df31bbd8aa30a9dc978f8a369 117 Gene3D G3DSA:2.60.120.10 36 111 2.2E-16 T 10-11-2016 IPR014710 RmlC-like jelly roll fold A4G23_RS21800 dd52237a8da1f4eb9e5de8dc737f3c1d 316 Pfam PF07730 Histidine kinase 126 192 7.6E-13 T 10-11-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4G23_RS21800 dd52237a8da1f4eb9e5de8dc737f3c1d 316 SMART SM00387 226 316 3.8E-12 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS21800 dd52237a8da1f4eb9e5de8dc737f3c1d 316 SUPERFAMILY SSF55874 205 313 9.82E-18 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS21800 dd52237a8da1f4eb9e5de8dc737f3c1d 316 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 228 313 3.6E-8 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS21800 dd52237a8da1f4eb9e5de8dc737f3c1d 316 Gene3D G3DSA:3.30.565.10 231 314 1.7E-9 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS01150 ff2d3cc3163bf5206a5f0e304d6f8753 88 SUPERFAMILY SSF56349 6 84 3.53E-9 T 10-11-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A4G23_RS01150 ff2d3cc3163bf5206a5f0e304d6f8753 88 Gene3D G3DSA:1.10.443.10 4 74 5.9E-12 T 10-11-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 A4G23_RS07435 e0d7d4a14f2b6422573bd0596ff9f81c 234 Gene3D G3DSA:1.10.10.60 16 71 3.7E-18 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS07435 e0d7d4a14f2b6422573bd0596ff9f81c 234 SUPERFAMILY SSF46689 16 94 1.28E-17 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS07435 e0d7d4a14f2b6422573bd0596ff9f81c 234 Gene3D G3DSA:1.10.357.10 72 212 1.7E-29 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS07435 e0d7d4a14f2b6422573bd0596ff9f81c 234 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 71 5.8E-5 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS07435 e0d7d4a14f2b6422573bd0596ff9f81c 234 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 5.8E-5 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS07435 e0d7d4a14f2b6422573bd0596ff9f81c 234 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 68 3.1E-14 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS20710 32f573cf0359fcfc422a5652c75f53fe 266 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 251 3.9E-16 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS20710 32f573cf0359fcfc422a5652c75f53fe 266 Gene3D G3DSA:1.10.3720.10 8 262 4.0E-50 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS20710 32f573cf0359fcfc422a5652c75f53fe 266 SUPERFAMILY SSF161098 3 255 5.05E-50 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS08205 55d1eebd0a109f9ebf5c1875b89212a5 372 SUPERFAMILY SSF53383 8 368 1.63E-113 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS08205 55d1eebd0a109f9ebf5c1875b89212a5 372 Gene3D G3DSA:3.90.1150.10 246 368 5.3E-34 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS08205 55d1eebd0a109f9ebf5c1875b89212a5 372 Gene3D G3DSA:3.40.640.10 9 244 1.0E-86 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS08205 55d1eebd0a109f9ebf5c1875b89212a5 372 PIRSF PIRSF000390 4 371 1.5E-116 T 10-11-2016 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A4G23_RS08205 55d1eebd0a109f9ebf5c1875b89212a5 372 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 16 365 2.7E-126 T 10-11-2016 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A4G23_RS17345 56915cd89813bb6cf98af8e49ec32814 529 Gene3D G3DSA:3.60.21.10 307 479 4.3E-22 T 10-11-2016 IPR029052 Metallo-dependent phosphatase-like A4G23_RS17345 56915cd89813bb6cf98af8e49ec32814 529 SUPERFAMILY SSF56300 303 526 6.81E-35 T 10-11-2016 IPR029052 Metallo-dependent phosphatase-like A4G23_RS17345 56915cd89813bb6cf98af8e49ec32814 529 Pfam PF00149 Calcineurin-like phosphoesterase 308 469 1.5E-11 T 10-11-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 A4G23_RS17385 98856e594c55a37af526a9539c9219e4 177 Gene3D G3DSA:1.10.3330.10 91 163 3.4E-15 T 10-11-2016 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394 A4G23_RS17385 98856e594c55a37af526a9539c9219e4 177 Gene3D G3DSA:1.10.3330.10 22 76 1.4E-10 T 10-11-2016 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394 A4G23_RS17385 98856e594c55a37af526a9539c9219e4 177 Pfam PF09349 OHCU decarboxylase 19 76 1.6E-6 T 10-11-2016 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394 A4G23_RS17385 98856e594c55a37af526a9539c9219e4 177 Pfam PF09349 OHCU decarboxylase 92 157 1.8E-9 T 10-11-2016 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394 A4G23_RS17385 98856e594c55a37af526a9539c9219e4 177 SUPERFAMILY SSF158694 15 160 9.16E-27 T 10-11-2016 A4G23_RS07980 22174a20434a30b940de72205080bace 502 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 338 409 2.5E-12 T 10-11-2016 IPR003959 ATPase, AAA-type, core GO:0005524 A4G23_RS07980 22174a20434a30b940de72205080bace 502 Gene3D G3DSA:3.40.1140.10 185 240 7.8E-12 T 10-11-2016 A4G23_RS07980 22174a20434a30b940de72205080bace 502 Gene3D G3DSA:3.40.1140.10 342 422 7.8E-12 T 10-11-2016 A4G23_RS07980 22174a20434a30b940de72205080bace 502 SUPERFAMILY SSF52540 184 412 1.19E-14 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS03950 ee5e8abaf7f840e6a4015c81564b76a3 160 SUPERFAMILY SSF55729 1 145 4.12E-23 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS03950 ee5e8abaf7f840e6a4015c81564b76a3 160 Gene3D G3DSA:3.40.630.30 2 148 1.0E-25 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS03950 ee5e8abaf7f840e6a4015c81564b76a3 160 Pfam PF00583 Acetyltransferase (GNAT) family 62 140 4.3E-10 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS00135 d0cf5fac3151fd1c570ae4f2e2dbf166 492 Gene3D G3DSA:3.40.50.980 180 318 5.0E-10 T 10-11-2016 A4G23_RS00135 d0cf5fac3151fd1c570ae4f2e2dbf166 492 Gene3D G3DSA:2.30.38.10 335 382 4.9E-4 T 10-11-2016 A4G23_RS00135 d0cf5fac3151fd1c570ae4f2e2dbf166 492 Gene3D G3DSA:3.30.300.30 384 479 1.5E-7 T 10-11-2016 A4G23_RS00135 d0cf5fac3151fd1c570ae4f2e2dbf166 492 Gene3D G3DSA:3.40.50.980 3 179 1.5E-19 T 10-11-2016 A4G23_RS00135 d0cf5fac3151fd1c570ae4f2e2dbf166 492 Pfam PF00501 AMP-binding enzyme 7 388 3.8E-37 T 10-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A4G23_RS00135 d0cf5fac3151fd1c570ae4f2e2dbf166 492 SUPERFAMILY SSF56801 2 484 4.45E-61 T 10-11-2016 A4G23_RS18720 ea959fb662a6427cef48ab3a6a071239 541 SUPERFAMILY SSF53474 220 283 5.31E-23 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS18720 ea959fb662a6427cef48ab3a6a071239 541 SUPERFAMILY SSF53474 330 513 5.31E-23 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS18720 ea959fb662a6427cef48ab3a6a071239 541 SUPERFAMILY SSF53474 113 177 5.31E-23 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS18720 ea959fb662a6427cef48ab3a6a071239 541 Gene3D G3DSA:3.40.50.1820 95 179 1.1E-60 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS18720 ea959fb662a6427cef48ab3a6a071239 541 Gene3D G3DSA:3.40.50.1820 223 348 1.1E-60 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS18720 ea959fb662a6427cef48ab3a6a071239 541 Gene3D G3DSA:3.40.50.1820 407 528 1.1E-60 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS18720 ea959fb662a6427cef48ab3a6a071239 541 Pfam PF08386 TAP-like protein 436 540 8.3E-31 T 10-11-2016 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal A4G23_RS18465 83ac6f1d4f3fc20619e7b63dae70134c 251 Gene3D G3DSA:2.140.10.30 19 250 2.4E-37 T 10-11-2016 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 A4G23_RS18465 83ac6f1d4f3fc20619e7b63dae70134c 251 SUPERFAMILY SSF82171 23 250 1.55E-20 T 10-11-2016 A4G23_RS18465 83ac6f1d4f3fc20619e7b63dae70134c 251 Pfam PF00930 Dipeptidyl peptidase IV (DPP IV) N-terminal region 115 250 1.9E-18 T 10-11-2016 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 A4G23_RS16375 98b765b541ef51d57a61419cd1743887 1298 SMART SM00663 310 589 6.6E-174 T 10-11-2016 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4G23_RS16375 98b765b541ef51d57a61419cd1743887 1298 Pfam PF04983 RNA polymerase Rpb1, domain 3 564 731 6.4E-22 T 10-11-2016 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4G23_RS16375 98b765b541ef51d57a61419cd1743887 1298 SUPERFAMILY SSF64484 5 1250 0.0 T 10-11-2016 A4G23_RS16375 98b765b541ef51d57a61419cd1743887 1298 Pfam PF00623 RNA polymerase Rpb1, domain 2 468 560 9.6E-28 T 10-11-2016 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4G23_RS16375 98b765b541ef51d57a61419cd1743887 1298 Pfam PF00623 RNA polymerase Rpb1, domain 2 419 480 1.3E-8 T 10-11-2016 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4G23_RS16375 98b765b541ef51d57a61419cd1743887 1298 Gene3D G3DSA:2.40.40.20 492 564 3.7E-38 T 10-11-2016 A4G23_RS16375 98b765b541ef51d57a61419cd1743887 1298 Gene3D G3DSA:2.40.40.20 424 451 3.7E-38 T 10-11-2016 A4G23_RS16375 98b765b541ef51d57a61419cd1743887 1298 Pfam PF05000 RNA polymerase Rpb1, domain 4 760 824 8.0E-14 T 10-11-2016 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4G23_RS16375 98b765b541ef51d57a61419cd1743887 1298 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 5 1259 10.04 T 10-11-2016 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4G23_RS16375 98b765b541ef51d57a61419cd1743887 1298 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 10 1250 0.0 T 10-11-2016 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4G23_RS16375 98b765b541ef51d57a61419cd1743887 1298 Pfam PF04997 RNA polymerase Rpb1, domain 1 7 417 4.9E-82 T 10-11-2016 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4G23_RS16375 98b765b541ef51d57a61419cd1743887 1298 Gene3D G3DSA:2.40.50.100 1040 1094 1.4E-9 T 10-11-2016 A4G23_RS16375 98b765b541ef51d57a61419cd1743887 1298 Pfam PF04998 RNA polymerase Rpb1, domain 5 838 1198 4.7E-65 T 10-11-2016 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4G23_RS19070 77e233015cc3373baaa2b2141ce6bf72 474 SUPERFAMILY SSF51206 106 220 2.49E-20 T 10-11-2016 IPR018490 Cyclic nucleotide-binding-like A4G23_RS19070 77e233015cc3373baaa2b2141ce6bf72 474 SMART SM00100 100 223 2.2E-6 T 10-11-2016 IPR000595 Cyclic nucleotide-binding domain A4G23_RS19070 77e233015cc3373baaa2b2141ce6bf72 474 Gene3D G3DSA:2.60.120.10 97 220 5.2E-19 T 10-11-2016 IPR014710 RmlC-like jelly roll fold A4G23_RS19070 77e233015cc3373baaa2b2141ce6bf72 474 Pfam PF00027 Cyclic nucleotide-binding domain 120 206 4.6E-16 T 10-11-2016 IPR000595 Cyclic nucleotide-binding domain A4G23_RS01025 e0626b8a392946b005b04c8800f27589 339 Pfam PF13641 Glycosyltransferase like family 2 6 196 2.4E-11 T 10-11-2016 A4G23_RS01025 e0626b8a392946b005b04c8800f27589 339 Gene3D G3DSA:3.90.550.10 10 198 1.6E-20 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS01025 e0626b8a392946b005b04c8800f27589 339 SUPERFAMILY SSF53448 9 199 8.44E-32 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS19105 6fd3815b73a69a294011b25f415916c9 403 Gene3D G3DSA:3.40.190.10 138 223 3.9E-6 T 10-11-2016 A4G23_RS19105 6fd3815b73a69a294011b25f415916c9 403 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 35 94 3.0E-19 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS19105 6fd3815b73a69a294011b25f415916c9 403 Gene3D G3DSA:1.10.10.10 32 110 2.4E-24 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS19105 6fd3815b73a69a294011b25f415916c9 403 Pfam PF03466 LysR substrate binding domain 136 250 2.8E-6 T 10-11-2016 IPR005119 LysR, substrate-binding A4G23_RS19105 6fd3815b73a69a294011b25f415916c9 403 SUPERFAMILY SSF53850 134 255 1.9E-7 T 10-11-2016 A4G23_RS19105 6fd3815b73a69a294011b25f415916c9 403 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 60 70 1.9E-7 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS19105 6fd3815b73a69a294011b25f415916c9 403 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 70 81 1.9E-7 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS19105 6fd3815b73a69a294011b25f415916c9 403 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 49 60 1.9E-7 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS19105 6fd3815b73a69a294011b25f415916c9 403 SUPERFAMILY SSF46785 32 114 2.49E-19 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS03400 9521ca5a31d3af1908feddca268182fd 406 Gene3D G3DSA:3.30.420.40 81 219 1.4E-30 T 10-11-2016 A4G23_RS03400 9521ca5a31d3af1908feddca268182fd 406 SUPERFAMILY SSF53067 86 397 3.4E-33 T 10-11-2016 A4G23_RS03400 9521ca5a31d3af1908feddca268182fd 406 SUPERFAMILY SSF46785 13 76 2.81E-11 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS03400 9521ca5a31d3af1908feddca268182fd 406 Pfam PF12802 MarR family 16 69 1.2E-7 T 10-11-2016 A4G23_RS03400 9521ca5a31d3af1908feddca268182fd 406 Gene3D G3DSA:1.10.10.10 11 76 9.6E-11 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS03400 9521ca5a31d3af1908feddca268182fd 406 Gene3D G3DSA:3.30.420.40 220 372 1.7E-26 T 10-11-2016 A4G23_RS03400 9521ca5a31d3af1908feddca268182fd 406 Pfam PF00480 ROK family 137 393 2.0E-26 T 10-11-2016 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A4G23_RS24655 3c58346a34ceedcaee48e34ec832beb1 78 Pfam PF04149 Domain of unknown function (DUF397) 17 69 1.0E-15 T 10-11-2016 IPR007278 Domain of unknown function DUF397 A4G23_RS03905 12c02faad7054de2db94750cf92dbb65 410 Gene3D G3DSA:3.40.1010.10 169 282 1.7E-39 T 10-11-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A4G23_RS03905 12c02faad7054de2db94750cf92dbb65 410 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 168 402 2.4E-84 T 10-11-2016 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 A4G23_RS03905 12c02faad7054de2db94750cf92dbb65 410 Gene3D G3DSA:3.30.950.10 283 404 3.2E-43 T 10-11-2016 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A4G23_RS03905 12c02faad7054de2db94750cf92dbb65 410 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 11 135 6.8E-19 T 10-11-2016 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 A4G23_RS03905 12c02faad7054de2db94750cf92dbb65 410 SUPERFAMILY SSF53790 166 404 1.22E-71 T 10-11-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A4G23_RS03905 12c02faad7054de2db94750cf92dbb65 410 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 247 280 - T 10-11-2016 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 A4G23_RS03905 12c02faad7054de2db94750cf92dbb65 410 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 169 380 5.5E-47 T 10-11-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A4G23_RS03905 12c02faad7054de2db94750cf92dbb65 410 Pfam PF13241 Putative NAD(P)-binding 14 121 1.9E-20 T 10-11-2016 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 A4G23_RS03905 12c02faad7054de2db94750cf92dbb65 410 SUPERFAMILY SSF51735 10 113 1.02E-17 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS03905 12c02faad7054de2db94750cf92dbb65 410 Gene3D G3DSA:3.40.50.720 10 115 3.6E-31 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS24160 8089efdf2c4edd209c4c378d0df12f27 276 Pfam PF00459 Inositol monophosphatase family 12 249 2.4E-56 T 10-11-2016 IPR000760 Inositol monophosphatase GO:0046854 A4G23_RS24160 8089efdf2c4edd209c4c378d0df12f27 276 Gene3D G3DSA:3.30.540.10 11 171 5.9E-38 T 10-11-2016 A4G23_RS24160 8089efdf2c4edd209c4c378d0df12f27 276 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 223 237 - T 10-11-2016 IPR020550 Inositol monophosphatase, conserved site GO:0046854 A4G23_RS24160 8089efdf2c4edd209c4c378d0df12f27 276 Gene3D G3DSA:3.40.190.80 172 255 6.1E-16 T 10-11-2016 A4G23_RS24160 8089efdf2c4edd209c4c378d0df12f27 276 SUPERFAMILY SSF56655 11 255 9.29E-60 T 10-11-2016 A4G23_RS24160 8089efdf2c4edd209c4c378d0df12f27 276 PRINTS PR00377 Inositol monophosphatase superfamily signature 189 210 1.5E-22 T 10-11-2016 IPR000760 Inositol monophosphatase GO:0046854 A4G23_RS24160 8089efdf2c4edd209c4c378d0df12f27 276 PRINTS PR00377 Inositol monophosphatase superfamily signature 69 85 1.5E-22 T 10-11-2016 IPR000760 Inositol monophosphatase GO:0046854 A4G23_RS24160 8089efdf2c4edd209c4c378d0df12f27 276 PRINTS PR00377 Inositol monophosphatase superfamily signature 220 244 1.5E-22 T 10-11-2016 IPR000760 Inositol monophosphatase GO:0046854 A4G23_RS24160 8089efdf2c4edd209c4c378d0df12f27 276 PRINTS PR00377 Inositol monophosphatase superfamily signature 47 67 1.5E-22 T 10-11-2016 IPR000760 Inositol monophosphatase GO:0046854 A4G23_RS24160 8089efdf2c4edd209c4c378d0df12f27 276 PRINTS PR00377 Inositol monophosphatase superfamily signature 96 112 1.5E-22 T 10-11-2016 IPR000760 Inositol monophosphatase GO:0046854 A4G23_RS24160 8089efdf2c4edd209c4c378d0df12f27 276 PRINTS PR00377 Inositol monophosphatase superfamily signature 145 168 1.5E-22 T 10-11-2016 IPR000760 Inositol monophosphatase GO:0046854 A4G23_RS24160 8089efdf2c4edd209c4c378d0df12f27 276 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 96 109 - T 10-11-2016 IPR020583 Inositol monophosphatase, metal-binding site A4G23_RS18550 2e191e12eaca75bab2885d788b14a039 55 Pfam PF11314 Protein of unknown function (DUF3117) 4 53 1.5E-28 T 10-11-2016 IPR021465 Protein of unknown function DUF3117 A4G23_RS26825 3c3227163b3f419cc2745fd8bef1829d 507 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 295 306 - T 10-11-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 A4G23_RS26825 3c3227163b3f419cc2745fd8bef1829d 507 SUPERFAMILY SSF53720 14 499 4.71E-159 T 10-11-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A4G23_RS26825 3c3227163b3f419cc2745fd8bef1829d 507 Pfam PF00171 Aldehyde dehydrogenase family 32 494 1.1E-160 T 10-11-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A4G23_RS26825 3c3227163b3f419cc2745fd8bef1829d 507 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 262 269 - T 10-11-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 A4G23_RS26825 3c3227163b3f419cc2745fd8bef1829d 507 Gene3D G3DSA:3.40.605.10 19 270 2.0E-89 T 10-11-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A4G23_RS26825 3c3227163b3f419cc2745fd8bef1829d 507 Gene3D G3DSA:3.40.309.10 271 470 9.0E-58 T 10-11-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 A4G23_RS12545 52c6e19f91564da94920c60f05f7cb08 332 Pfam PF01384 Phosphate transporter family 20 160 1.1E-39 T 10-11-2016 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 A4G23_RS12545 52c6e19f91564da94920c60f05f7cb08 332 Pfam PF01384 Phosphate transporter family 165 320 2.7E-47 T 10-11-2016 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 A4G23_RS03085 fe5f681bd139acdaad15a8ac99d98db1 310 Pfam PF05949 Bacterial protein of unknown function (DUF881) 137 279 9.0E-37 T 10-11-2016 IPR010273 Protein of unknown function DUF881 A4G23_RS22460 8eabe7b61c747544cb49c89fe64cb645 485 Pfam PF13450 NAD(P)-binding Rossmann-like domain 63 129 2.6E-11 T 10-11-2016 A4G23_RS22460 8eabe7b61c747544cb49c89fe64cb645 485 Gene3D G3DSA:3.50.50.60 58 154 1.1E-23 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS22460 8eabe7b61c747544cb49c89fe64cb645 485 Gene3D G3DSA:3.50.50.60 246 353 1.1E-23 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS22460 8eabe7b61c747544cb49c89fe64cb645 485 Pfam PF01593 Flavin containing amine oxidoreductase 262 329 2.0E-5 T 10-11-2016 IPR002937 Amine oxidase GO:0016491|GO:0055114 A4G23_RS22460 8eabe7b61c747544cb49c89fe64cb645 485 SUPERFAMILY SSF51905 54 362 1.25E-28 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS22460 8eabe7b61c747544cb49c89fe64cb645 485 SUPERFAMILY SSF51905 431 465 1.25E-28 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS17320 36fe4f3e4a37a49fe24e09872e2a8565 337 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 14 24 - T 10-11-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4G23_RS17320 36fe4f3e4a37a49fe24e09872e2a8565 337 SUPERFAMILY SSF52374 7 332 2.97E-99 T 10-11-2016 A4G23_RS17320 36fe4f3e4a37a49fe24e09872e2a8565 337 Pfam PF00579 tRNA synthetases class I (W and Y) 4 286 8.3E-79 T 10-11-2016 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4G23_RS17320 36fe4f3e4a37a49fe24e09872e2a8565 337 Gene3D G3DSA:1.10.240.10 210 300 5.0E-18 T 10-11-2016 A4G23_RS17320 36fe4f3e4a37a49fe24e09872e2a8565 337 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 6 332 3.9E-106 T 10-11-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A4G23_RS17320 36fe4f3e4a37a49fe24e09872e2a8565 337 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 19 35 7.1E-27 T 10-11-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A4G23_RS17320 36fe4f3e4a37a49fe24e09872e2a8565 337 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 69 88 7.1E-27 T 10-11-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A4G23_RS17320 36fe4f3e4a37a49fe24e09872e2a8565 337 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 146 167 7.1E-27 T 10-11-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A4G23_RS17320 36fe4f3e4a37a49fe24e09872e2a8565 337 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 199 209 7.1E-27 T 10-11-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A4G23_RS17320 36fe4f3e4a37a49fe24e09872e2a8565 337 Gene3D G3DSA:3.40.50.620 6 209 2.9E-85 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS17320 36fe4f3e4a37a49fe24e09872e2a8565 337 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 5 333 42.093 T 10-11-2016 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 A4G23_RS15415 bff014200c7313397e4454390ab330e7 155 Pfam PF00583 Acetyltransferase (GNAT) family 39 108 3.1E-10 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS15415 bff014200c7313397e4454390ab330e7 155 SUPERFAMILY SSF55729 27 117 1.34E-19 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS15415 bff014200c7313397e4454390ab330e7 155 Gene3D G3DSA:3.40.630.30 2 133 3.3E-28 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS18315 43cc6f0bfe33e92fac03b26fa1091a7b 178 Gene3D G3DSA:3.90.79.10 34 153 6.5E-25 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS18315 43cc6f0bfe33e92fac03b26fa1091a7b 178 ProSitePatterns PS00893 Nudix box signature. 68 89 - T 10-11-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A4G23_RS18315 43cc6f0bfe33e92fac03b26fa1091a7b 178 SUPERFAMILY SSF55811 31 166 6.63E-25 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS18315 43cc6f0bfe33e92fac03b26fa1091a7b 178 PRINTS PR00502 NUDIX hydrolase family signature 63 77 6.9E-6 T 10-11-2016 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A4G23_RS18315 43cc6f0bfe33e92fac03b26fa1091a7b 178 PRINTS PR00502 NUDIX hydrolase family signature 77 92 6.9E-6 T 10-11-2016 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A4G23_RS18315 43cc6f0bfe33e92fac03b26fa1091a7b 178 Pfam PF00293 NUDIX domain 34 156 9.7E-19 T 10-11-2016 IPR000086 NUDIX hydrolase domain GO:0016787 A4G23_RS13625 5250fc9c61e8205acf8caf7fd47eef5f 144 Pfam PF05719 Golgi phosphoprotein 3 (GPP34) 1 137 1.2E-23 T 10-11-2016 IPR008628 Golgi phosphoprotein 3 GO:0048193|GO:0070273 A4G23_RS13625 5250fc9c61e8205acf8caf7fd47eef5f 144 Gene3D G3DSA:1.10.3630.10 1 135 6.5E-17 T 10-11-2016 A4G23_RS17475 e5a52b8888b7076fb90176c2faf97fa7 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 160 178 2.2E-6 T 10-11-2016 A4G23_RS17475 e5a52b8888b7076fb90176c2faf97fa7 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 204 222 2.2E-6 T 10-11-2016 A4G23_RS17475 e5a52b8888b7076fb90176c2faf97fa7 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 2.2E-6 T 10-11-2016 A4G23_RS17475 e5a52b8888b7076fb90176c2faf97fa7 468 SUPERFAMILY SSF51905 4 246 6.96E-23 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS17475 e5a52b8888b7076fb90176c2faf97fa7 468 Gene3D G3DSA:3.50.50.60 294 349 6.7E-12 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS17475 e5a52b8888b7076fb90176c2faf97fa7 468 Gene3D G3DSA:3.50.50.60 209 240 6.7E-12 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS17475 e5a52b8888b7076fb90176c2faf97fa7 468 SUPERFAMILY SSF51905 183 237 1.82E-15 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS17475 e5a52b8888b7076fb90176c2faf97fa7 468 SUPERFAMILY SSF51905 289 419 1.82E-15 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS17475 e5a52b8888b7076fb90176c2faf97fa7 468 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 5 351 1.9E-110 T 10-11-2016 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase A4G23_RS17475 e5a52b8888b7076fb90176c2faf97fa7 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 8 30 5.8E-5 T 10-11-2016 A4G23_RS17475 e5a52b8888b7076fb90176c2faf97fa7 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 204 229 5.8E-5 T 10-11-2016 A4G23_RS17475 e5a52b8888b7076fb90176c2faf97fa7 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 163 172 5.8E-5 T 10-11-2016 A4G23_RS17475 e5a52b8888b7076fb90176c2faf97fa7 468 Gene3D G3DSA:3.50.50.60 88 208 6.7E-14 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS12190 5d3fb5c92c15a580f434348b351f66bd 246 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 110 117 - T 10-11-2016 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 A4G23_RS12190 5d3fb5c92c15a580f434348b351f66bd 246 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 12 237 4.0E-69 T 10-11-2016 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 A4G23_RS12190 5d3fb5c92c15a580f434348b351f66bd 246 Gene3D G3DSA:3.90.550.10 9 242 6.4E-68 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS12190 5d3fb5c92c15a580f434348b351f66bd 246 SUPERFAMILY SSF53448 10 237 3.6E-54 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS12190 5d3fb5c92c15a580f434348b351f66bd 246 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 9 240 29.517 T 10-11-2016 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 A4G23_RS12190 5d3fb5c92c15a580f434348b351f66bd 246 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 11 238 3.2E-64 T 10-11-2016 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 A4G23_RS19445 2d9f9b13d2ced11244c5c798e78330d7 356 Gene3D G3DSA:3.40.50.300 2 344 3.2E-37 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS19445 2d9f9b13d2ced11244c5c798e78330d7 356 Pfam PF13614 AAA domain 2 213 1.3E-29 T 10-11-2016 IPR025669 AAA domain A4G23_RS19445 2d9f9b13d2ced11244c5c798e78330d7 356 SUPERFAMILY SSF52540 86 227 1.84E-30 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS19445 2d9f9b13d2ced11244c5c798e78330d7 356 SUPERFAMILY SSF52540 1 52 1.84E-30 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS04410 d852a0823dafb773140adc19d24c204d 235 TIGRFAM TIGR03848 MSMEG_4193: probable phosphomutase, MSMEG_4193 family 3 203 1.1E-94 T 10-11-2016 IPR022492 Phosphomutase MSMEG4193, putative A4G23_RS04410 d852a0823dafb773140adc19d24c204d 235 SMART SM00855 3 162 1.5E-20 T 10-11-2016 IPR013078 Histidine phosphatase superfamily, clade-1 A4G23_RS04410 d852a0823dafb773140adc19d24c204d 235 Gene3D G3DSA:3.40.50.1240 2 207 4.3E-45 T 10-11-2016 IPR029033 Histidine phosphatase superfamily A4G23_RS04410 d852a0823dafb773140adc19d24c204d 235 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 202 1.1E-47 T 10-11-2016 IPR013078 Histidine phosphatase superfamily, clade-1 A4G23_RS04410 d852a0823dafb773140adc19d24c204d 235 SUPERFAMILY SSF53254 1 208 1.5E-44 T 10-11-2016 IPR029033 Histidine phosphatase superfamily A4G23_RS14405 a6f46d42a78a28b07e98ba300d5a6078 759 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 399 410 - T 10-11-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4G23_RS14405 a6f46d42a78a28b07e98ba300d5a6078 759 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 308 319 - T 10-11-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4G23_RS14405 a6f46d42a78a28b07e98ba300d5a6078 759 Pfam PF02754 Cysteine-rich domain 622 709 1.0E-18 T 10-11-2016 IPR004017 Cysteine-rich domain A4G23_RS14405 a6f46d42a78a28b07e98ba300d5a6078 759 Pfam PF02754 Cysteine-rich domain 484 583 1.8E-13 T 10-11-2016 IPR004017 Cysteine-rich domain A4G23_RS14405 a6f46d42a78a28b07e98ba300d5a6078 759 SUPERFAMILY SSF46548 294 344 8.89E-21 T 10-11-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 A4G23_RS14405 a6f46d42a78a28b07e98ba300d5a6078 759 SUPERFAMILY SSF46548 381 427 8.89E-21 T 10-11-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 A4G23_RS14405 a6f46d42a78a28b07e98ba300d5a6078 759 Pfam PF13183 4Fe-4S dicluster domain 305 413 6.4E-14 T 10-11-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4G23_RS14405 a6f46d42a78a28b07e98ba300d5a6078 759 Gene3D G3DSA:1.10.1060.10 378 428 8.0E-32 T 10-11-2016 A4G23_RS14405 a6f46d42a78a28b07e98ba300d5a6078 759 Gene3D G3DSA:1.10.1060.10 280 341 8.0E-32 T 10-11-2016 A4G23_RS17580 05311f63fea00bf6141ec82ce194a739 349 Gene3D G3DSA:3.40.50.2300 36 170 4.0E-45 T 10-11-2016 A4G23_RS17580 05311f63fea00bf6141ec82ce194a739 349 Gene3D G3DSA:3.40.50.2300 171 248 9.7E-6 T 10-11-2016 A4G23_RS17580 05311f63fea00bf6141ec82ce194a739 349 Pfam PF02608 Basic membrane protein 46 331 8.4E-55 T 10-11-2016 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 A4G23_RS17580 05311f63fea00bf6141ec82ce194a739 349 SUPERFAMILY SSF53822 52 293 7.85E-9 T 10-11-2016 IPR028082 Periplasmic binding protein-like I A4G23_RS05270 e6d9f31c3dbee0e922c2a4521558c20d 376 SUPERFAMILY SSF53474 125 372 2.18E-31 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS05270 e6d9f31c3dbee0e922c2a4521558c20d 376 Gene3D G3DSA:3.40.50.1820 134 372 1.5E-27 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS15670 d11acba5e0d838a590a2c23f639069c1 147 Pfam PF09683 Bacteriocin (Lactococcin_972) 79 144 1.3E-14 T 10-11-2016 IPR006540 Bacteriocin, lactococcin 972 A4G23_RS20875 1046432d884c84c2feac5de9c481e1a6 138 Pfam PF14530 Domain of unknown function (DUF4439) 6 136 2.7E-42 T 10-11-2016 IPR029447 Domain of unknown function DUF4439 A4G23_RS20875 1046432d884c84c2feac5de9c481e1a6 138 Gene3D G3DSA:1.20.1260.10 3 126 5.8E-41 T 10-11-2016 IPR012347 Ferritin-related A4G23_RS20875 1046432d884c84c2feac5de9c481e1a6 138 SUPERFAMILY SSF47240 4 137 3.34E-34 T 10-11-2016 IPR009078 Ferritin-like superfamily A4G23_RS12120 effa35632fa562d7ae41adf4fd645e8d 142 Pfam PF00583 Acetyltransferase (GNAT) family 41 120 5.2E-18 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS12120 effa35632fa562d7ae41adf4fd645e8d 142 SUPERFAMILY SSF55729 2 134 3.09E-34 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS12120 effa35632fa562d7ae41adf4fd645e8d 142 Gene3D G3DSA:3.40.630.30 1 139 1.8E-53 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS19410 f9e0f7a4e3fc956eb6eec4eebc6fbaf2 458 Gene3D G3DSA:2.40.10.10 18 150 3.0E-6 T 10-11-2016 A4G23_RS19410 f9e0f7a4e3fc956eb6eec4eebc6fbaf2 458 Pfam PF13365 Trypsin-like peptidase domain 31 185 1.0E-13 T 10-11-2016 A4G23_RS19410 f9e0f7a4e3fc956eb6eec4eebc6fbaf2 458 SUPERFAMILY SSF50494 17 213 7.48E-18 T 10-11-2016 IPR009003 Peptidase S1, PA clan A4G23_RS19495 053de367fdf6886a6261ecf008497a0c 592 Gene3D G3DSA:2.40.10.10 139 209 3.2E-11 T 10-11-2016 A4G23_RS19495 053de367fdf6886a6261ecf008497a0c 592 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 296 307 - T 10-11-2016 IPR033116 Serine proteases, trypsin family, serine active site A4G23_RS19495 053de367fdf6886a6261ecf008497a0c 592 SMART SM00020 95 342 6.6E-43 T 10-11-2016 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 A4G23_RS19495 053de367fdf6886a6261ecf008497a0c 592 Gene3D G3DSA:2.40.10.10 210 344 3.0E-29 T 10-11-2016 A4G23_RS19495 053de367fdf6886a6261ecf008497a0c 592 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 492 554 2.7E-10 T 10-11-2016 A4G23_RS19495 053de367fdf6886a6261ecf008497a0c 592 SUPERFAMILY SSF50494 93 340 8.42E-53 T 10-11-2016 IPR009003 Peptidase S1, PA clan A4G23_RS19495 053de367fdf6886a6261ecf008497a0c 592 Gene3D G3DSA:2.40.10.10 96 138 1.1E-16 T 10-11-2016 A4G23_RS19495 053de367fdf6886a6261ecf008497a0c 592 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 199 213 1.4E-9 T 10-11-2016 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 A4G23_RS19495 053de367fdf6886a6261ecf008497a0c 592 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 295 307 1.4E-9 T 10-11-2016 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 A4G23_RS19495 053de367fdf6886a6261ecf008497a0c 592 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 133 148 1.4E-9 T 10-11-2016 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 A4G23_RS19495 053de367fdf6886a6261ecf008497a0c 592 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 143 148 - T 10-11-2016 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 A4G23_RS19495 053de367fdf6886a6261ecf008497a0c 592 SUPERFAMILY SSF69318 299 577 7.85E-25 T 10-11-2016 A4G23_RS19495 053de367fdf6886a6261ecf008497a0c 592 Gene3D G3DSA:2.115.10.10 350 375 1.6E-10 T 10-11-2016 IPR023294 Tachylectin 2 A4G23_RS19495 053de367fdf6886a6261ecf008497a0c 592 Gene3D G3DSA:2.115.10.10 410 537 1.6E-10 T 10-11-2016 IPR023294 Tachylectin 2 A4G23_RS19495 053de367fdf6886a6261ecf008497a0c 592 Gene3D G3DSA:2.115.10.10 543 591 1.4E-4 T 10-11-2016 IPR023294 Tachylectin 2 A4G23_RS19495 053de367fdf6886a6261ecf008497a0c 592 Pfam PF00089 Trypsin 96 338 5.0E-40 T 10-11-2016 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 A4G23_RS02365 39a2974e4fb320b99e7f9aa69b40fc4b 140 Pfam PF01894 Uncharacterised protein family UPF0047 22 136 4.1E-23 T 10-11-2016 IPR001602 Uncharacterised protein family UPF0047 A4G23_RS02365 39a2974e4fb320b99e7f9aa69b40fc4b 140 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 9 140 6.7E-22 T 10-11-2016 IPR001602 Uncharacterised protein family UPF0047 A4G23_RS02365 39a2974e4fb320b99e7f9aa69b40fc4b 140 PIRSF PIRSF004681 4 140 3.0E-29 T 10-11-2016 IPR001602 Uncharacterised protein family UPF0047 A4G23_RS02365 39a2974e4fb320b99e7f9aa69b40fc4b 140 SUPERFAMILY SSF111038 6 140 1.2E-32 T 10-11-2016 IPR001602 Uncharacterised protein family UPF0047 A4G23_RS02365 39a2974e4fb320b99e7f9aa69b40fc4b 140 Gene3D G3DSA:2.60.120.460 5 140 1.4E-33 T 10-11-2016 IPR001602 Uncharacterised protein family UPF0047 A4G23_RS09750 abe01697a1b0baa4da250fe09b6a7d03 414 Gene3D G3DSA:1.10.510.10 73 263 2.9E-47 T 10-11-2016 A4G23_RS09750 abe01697a1b0baa4da250fe09b6a7d03 414 Gene3D G3DSA:3.30.200.20 4 72 6.4E-16 T 10-11-2016 A4G23_RS09750 abe01697a1b0baa4da250fe09b6a7d03 414 SMART SM00220 9 270 7.5E-60 T 10-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4G23_RS09750 abe01697a1b0baa4da250fe09b6a7d03 414 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 126 138 - T 10-11-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 A4G23_RS09750 abe01697a1b0baa4da250fe09b6a7d03 414 SUPERFAMILY SSF56112 6 269 2.7E-66 T 10-11-2016 IPR011009 Protein kinase-like domain A4G23_RS09750 abe01697a1b0baa4da250fe09b6a7d03 414 Pfam PF00069 Protein kinase domain 9 263 2.8E-45 T 10-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4G23_RS03765 b1dc72b3882a263e2a4a9a45e7a6b666 303 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 9 293 4.8E-62 T 10-11-2016 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 A4G23_RS09485 c6156978fb7c50f99c9faabc97dfea4d 444 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 16 385 4.2E-128 T 10-11-2016 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 A4G23_RS09485 c6156978fb7c50f99c9faabc97dfea4d 444 SUPERFAMILY SSF54675 13 144 1.05E-43 T 10-11-2016 A4G23_RS09485 c6156978fb7c50f99c9faabc97dfea4d 444 PIRSF PIRSF000484 9 441 1.4E-99 T 10-11-2016 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 A4G23_RS09485 c6156978fb7c50f99c9faabc97dfea4d 444 SUPERFAMILY SSF51690 146 438 2.8E-76 T 10-11-2016 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 A4G23_RS09485 c6156978fb7c50f99c9faabc97dfea4d 444 Gene3D G3DSA:3.20.140.10 13 379 1.6E-89 T 10-11-2016 A4G23_RS08620 f8a7f6fac39dfea1bf99e93683c0bdc4 259 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 76 1.1E-17 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS08620 f8a7f6fac39dfea1bf99e93683c0bdc4 259 Pfam PF07702 UTRA domain 109 249 6.7E-28 T 10-11-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A4G23_RS08620 f8a7f6fac39dfea1bf99e93683c0bdc4 259 Gene3D G3DSA:3.40.1410.10 78 253 2.0E-53 T 10-11-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain A4G23_RS08620 f8a7f6fac39dfea1bf99e93683c0bdc4 259 SMART SM00866 108 250 1.2E-25 T 10-11-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A4G23_RS08620 f8a7f6fac39dfea1bf99e93683c0bdc4 259 SUPERFAMILY SSF46785 9 85 1.27E-20 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS08620 f8a7f6fac39dfea1bf99e93683c0bdc4 259 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 50 4.2E-5 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS08620 f8a7f6fac39dfea1bf99e93683c0bdc4 259 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 66 4.2E-5 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS08620 f8a7f6fac39dfea1bf99e93683c0bdc4 259 SMART SM00345 17 76 2.6E-19 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS08620 f8a7f6fac39dfea1bf99e93683c0bdc4 259 SUPERFAMILY SSF64288 64 255 2.57E-35 T 10-11-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain A4G23_RS08620 f8a7f6fac39dfea1bf99e93683c0bdc4 259 Gene3D G3DSA:1.10.10.10 10 77 6.9E-25 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS16555 3ee661898ab6549975b04015a8709dab 292 SMART SM00530 39 94 4.8E-6 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS16555 3ee661898ab6549975b04015a8709dab 292 Pfam PF13560 Helix-turn-helix domain 37 90 6.7E-12 T 10-11-2016 A4G23_RS16555 3ee661898ab6549975b04015a8709dab 292 SUPERFAMILY SSF47413 34 88 2.43E-7 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS16555 3ee661898ab6549975b04015a8709dab 292 Gene3D G3DSA:1.10.260.40 35 88 5.9E-8 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS09370 87c53a522f7524842fff16d1f2f4073b 872 Gene3D G3DSA:3.40.710.10 387 820 4.2E-93 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS09370 87c53a522f7524842fff16d1f2f4073b 872 Pfam PF00905 Penicillin binding protein transpeptidase domain 489 751 4.3E-30 T 10-11-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A4G23_RS09370 87c53a522f7524842fff16d1f2f4073b 872 Pfam PF00912 Transglycosylase 211 386 5.9E-59 T 10-11-2016 IPR001264 Glycosyl transferase, family 51 A4G23_RS09370 87c53a522f7524842fff16d1f2f4073b 872 SUPERFAMILY SSF56601 419 802 8.65E-78 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS09370 87c53a522f7524842fff16d1f2f4073b 872 SUPERFAMILY SSF56601 371 390 8.65E-78 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS09370 87c53a522f7524842fff16d1f2f4073b 872 SUPERFAMILY SSF53955 201 401 1.77E-65 T 10-11-2016 IPR023346 Lysozyme-like domain A4G23_RS09370 87c53a522f7524842fff16d1f2f4073b 872 Gene3D G3DSA:1.10.3810.10 212 386 4.0E-65 T 10-11-2016 A4G23_RS08495 e7103229e5aebbed9942dce3a4c4f9aa 279 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 22 242 1.6E-10 T 10-11-2016 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 A4G23_RS08495 e7103229e5aebbed9942dce3a4c4f9aa 279 Gene3D G3DSA:3.30.420.40 115 230 4.8E-4 T 10-11-2016 A4G23_RS08495 e7103229e5aebbed9942dce3a4c4f9aa 279 SUPERFAMILY SSF53067 55 246 5.98E-33 T 10-11-2016 A4G23_RS06470 1a3d4efcfbcb363fa20c6f685fc32803 258 Gene3D G3DSA:3.60.21.10 90 249 9.8E-21 T 10-11-2016 IPR029052 Metallo-dependent phosphatase-like A4G23_RS06470 1a3d4efcfbcb363fa20c6f685fc32803 258 Gene3D G3DSA:3.60.21.10 1 34 9.8E-21 T 10-11-2016 IPR029052 Metallo-dependent phosphatase-like A4G23_RS06470 1a3d4efcfbcb363fa20c6f685fc32803 258 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 246 2.0E-8 T 10-11-2016 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 A4G23_RS06470 1a3d4efcfbcb363fa20c6f685fc32803 258 SUPERFAMILY SSF56300 88 249 1.31E-34 T 10-11-2016 IPR029052 Metallo-dependent phosphatase-like A4G23_RS06470 1a3d4efcfbcb363fa20c6f685fc32803 258 SUPERFAMILY SSF56300 1 46 1.31E-34 T 10-11-2016 IPR029052 Metallo-dependent phosphatase-like A4G23_RS01750 448c9ecdb2d80d47205412b650ef20d6 415 SUPERFAMILY SSF53448 31 263 1.59E-32 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS01750 448c9ecdb2d80d47205412b650ef20d6 415 Pfam PF13641 Glycosyltransferase like family 2 43 262 1.7E-18 T 10-11-2016 A4G23_RS01750 448c9ecdb2d80d47205412b650ef20d6 415 Gene3D G3DSA:3.90.550.10 43 263 1.9E-22 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS01750 448c9ecdb2d80d47205412b650ef20d6 415 TIGRFAM TIGR03469 HpnB: hopene-associated glycosyltransferase HpnB 7 405 1.6E-140 T 10-11-2016 IPR017832 Glycosyl transferase, family 2, hopene-associated, HpnB A4G23_RS05590 68f9743429a0d821af091fb063bcd2a2 308 SMART SM00382 31 209 1.7E-13 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS05590 68f9743429a0d821af091fb063bcd2a2 308 Gene3D G3DSA:3.40.50.300 3 221 1.3E-62 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05590 68f9743429a0d821af091fb063bcd2a2 308 SUPERFAMILY SSF52540 5 220 1.59E-56 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05590 68f9743429a0d821af091fb063bcd2a2 308 Pfam PF00005 ABC transporter 23 161 1.3E-22 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS05590 68f9743429a0d821af091fb063bcd2a2 308 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS02710 dbd8922de4b1d104a68f91996470df26 274 Pfam PF08241 Methyltransferase domain 69 166 7.4E-22 T 10-11-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 A4G23_RS02710 dbd8922de4b1d104a68f91996470df26 274 Gene3D G3DSA:3.40.50.150 29 274 5.5E-49 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS02710 dbd8922de4b1d104a68f91996470df26 274 SUPERFAMILY SSF53335 12 274 7.03E-51 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS24775 d37ec8633ae9d328144f78efaf19940e 292 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 18 259 6.7E-52 T 10-11-2016 IPR018713 Domain of unknown function DUF2236 A4G23_RS10120 48cacd5e031440f31f6989955b88f803 226 SMART SM00448 2 113 1.0E-40 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS10120 48cacd5e031440f31f6989955b88f803 226 Pfam PF00072 Response regulator receiver domain 4 114 1.4E-27 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS10120 48cacd5e031440f31f6989955b88f803 226 Gene3D G3DSA:1.10.10.10 126 225 9.7E-36 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS10120 48cacd5e031440f31f6989955b88f803 226 Gene3D G3DSA:3.40.50.2300 2 121 8.8E-40 T 10-11-2016 A4G23_RS10120 48cacd5e031440f31f6989955b88f803 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 223 3.7E-28 T 10-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4G23_RS10120 48cacd5e031440f31f6989955b88f803 226 SMART SM00862 147 223 4.4E-29 T 10-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4G23_RS10120 48cacd5e031440f31f6989955b88f803 226 SUPERFAMILY SSF52172 1 185 1.4E-40 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS04125 45c0639b5ba5b8cd7ae6ca10e50eb143 198 SUPERFAMILY SSF55200 70 154 3.27E-32 T 10-11-2016 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 A4G23_RS04125 45c0639b5ba5b8cd7ae6ca10e50eb143 198 Gene3D G3DSA:3.30.110.10 64 156 1.5E-38 T 10-11-2016 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 A4G23_RS04125 45c0639b5ba5b8cd7ae6ca10e50eb143 198 Gene3D G3DSA:3.10.20.80 1 63 6.7E-28 T 10-11-2016 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 A4G23_RS04125 45c0639b5ba5b8cd7ae6ca10e50eb143 198 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 1 61 4.9E-24 T 10-11-2016 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 A4G23_RS04125 45c0639b5ba5b8cd7ae6ca10e50eb143 198 SUPERFAMILY SSF54364 1 63 4.58E-23 T 10-11-2016 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 A4G23_RS04125 45c0639b5ba5b8cd7ae6ca10e50eb143 198 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 1 155 5.3E-57 T 10-11-2016 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 A4G23_RS04125 45c0639b5ba5b8cd7ae6ca10e50eb143 198 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 69 152 5.1E-34 T 10-11-2016 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 A4G23_RS04125 45c0639b5ba5b8cd7ae6ca10e50eb143 198 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 1 155 25.629 T 10-11-2016 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 A4G23_RS16070 deb05fd79d8a679bdafb4378d1338dfd 449 SMART SM00928 339 384 2.9E-26 T 10-11-2016 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16070 deb05fd79d8a679bdafb4378d1338dfd 449 SUPERFAMILY SSF140490 335 434 3.01E-38 T 10-11-2016 A4G23_RS16070 deb05fd79d8a679bdafb4378d1338dfd 449 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 352 363 - T 10-11-2016 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16070 deb05fd79d8a679bdafb4378d1338dfd 449 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 178 193 - T 10-11-2016 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16070 deb05fd79d8a679bdafb4378d1338dfd 449 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 341 424 1.1E-32 T 10-11-2016 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16070 deb05fd79d8a679bdafb4378d1338dfd 449 TIGRFAM TIGR01959 nuoF_fam: NADH oxidoreductase (quinone), F subunit 23 425 7.7E-191 T 10-11-2016 IPR011537 NADH ubiquinone oxidoreductase, F subunit GO:0010181|GO:0016651|GO:0051287|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16070 deb05fd79d8a679bdafb4378d1338dfd 449 SUPERFAMILY SSF142984 253 334 3.27E-21 T 10-11-2016 A4G23_RS16070 deb05fd79d8a679bdafb4378d1338dfd 449 Pfam PF10531 SLBB domain 255 301 9.8E-8 T 10-11-2016 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16070 deb05fd79d8a679bdafb4378d1338dfd 449 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 59 230 2.6E-45 T 10-11-2016 IPR011538 NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16070 deb05fd79d8a679bdafb4378d1338dfd 449 SUPERFAMILY SSF142019 20 250 5.1E-86 T 10-11-2016 A4G23_RS26985 df9382b77ce9e358be4fec0373b6fab3 410 Gene3D G3DSA:3.40.50.80 278 398 2.0E-24 T 10-11-2016 A4G23_RS26985 df9382b77ce9e358be4fec0373b6fab3 410 Pfam PF00970 Oxidoreductase FAD-binding domain 190 269 7.9E-6 T 10-11-2016 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 A4G23_RS26985 df9382b77ce9e358be4fec0373b6fab3 410 PRINTS PR00410 Phenol hydroxylase reductase family signature 204 216 9.8E-8 T 10-11-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 A4G23_RS26985 df9382b77ce9e358be4fec0373b6fab3 410 PRINTS PR00410 Phenol hydroxylase reductase family signature 368 376 9.8E-8 T 10-11-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 A4G23_RS26985 df9382b77ce9e358be4fec0373b6fab3 410 PRINTS PR00410 Phenol hydroxylase reductase family signature 282 301 9.8E-8 T 10-11-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 A4G23_RS26985 df9382b77ce9e358be4fec0373b6fab3 410 SUPERFAMILY SSF46458 53 167 1.11E-22 T 10-11-2016 IPR009050 Globin-like A4G23_RS26985 df9382b77ce9e358be4fec0373b6fab3 410 Pfam PF00042 Globin 42 133 7.9E-7 T 10-11-2016 IPR000971 Globin GO:0019825|GO:0020037 A4G23_RS26985 df9382b77ce9e358be4fec0373b6fab3 410 SUPERFAMILY SSF63380 177 271 1.65E-17 T 10-11-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 A4G23_RS26985 df9382b77ce9e358be4fec0373b6fab3 410 Pfam PF00175 Oxidoreductase NAD-binding domain 284 381 1.6E-7 T 10-11-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 A4G23_RS26985 df9382b77ce9e358be4fec0373b6fab3 410 SUPERFAMILY SSF52343 275 398 2.75E-24 T 10-11-2016 A4G23_RS26985 df9382b77ce9e358be4fec0373b6fab3 410 Gene3D G3DSA:1.10.490.10 55 169 1.0E-25 T 10-11-2016 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 A4G23_RS26985 df9382b77ce9e358be4fec0373b6fab3 410 Gene3D G3DSA:2.40.30.10 177 272 4.8E-18 T 10-11-2016 A4G23_RS27150 4b882d354fe1484239129cd67defd389 74 PRINTS PR00352 3Fe-4S ferredoxin signature 49 61 4.5E-6 T 10-11-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A4G23_RS27150 4b882d354fe1484239129cd67defd389 74 PRINTS PR00352 3Fe-4S ferredoxin signature 10 21 4.5E-6 T 10-11-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A4G23_RS27150 4b882d354fe1484239129cd67defd389 74 PRINTS PR00352 3Fe-4S ferredoxin signature 21 31 4.5E-6 T 10-11-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A4G23_RS27150 4b882d354fe1484239129cd67defd389 74 SUPERFAMILY SSF54862 6 63 6.67E-9 T 10-11-2016 A4G23_RS27150 4b882d354fe1484239129cd67defd389 74 Pfam PF13459 4Fe-4S single cluster domain 8 63 3.2E-10 T 10-11-2016 A4G23_RS27150 4b882d354fe1484239129cd67defd389 74 Gene3D G3DSA:3.30.70.20 6 67 3.0E-13 T 10-11-2016 A4G23_RS18635 abdaa877c28f89c867a7a3712fd1646b 291 Pfam PF01936 NYN domain 27 171 1.0E-10 T 10-11-2016 IPR021139 NYN domain, limkain-b1-type A4G23_RS18635 abdaa877c28f89c867a7a3712fd1646b 291 Gene3D G3DSA:3.40.50.1010 21 169 6.4E-16 T 10-11-2016 IPR029060 PIN domain-like A4G23_RS06220 9866b26bdcb47683fc16372b4b442af5 242 PIRSF PIRSF004848 4 242 3.6E-64 T 10-11-2016 IPR011078 Uncharacterised protein family UPF0001 A4G23_RS06220 9866b26bdcb47683fc16372b4b442af5 242 Pfam PF01168 Alanine racemase, N-terminal domain 14 239 1.8E-24 T 10-11-2016 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4G23_RS06220 9866b26bdcb47683fc16372b4b442af5 242 Gene3D G3DSA:3.20.20.10 6 239 8.1E-82 T 10-11-2016 IPR029066 PLP-binding barrel A4G23_RS06220 9866b26bdcb47683fc16372b4b442af5 242 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 12 238 2.1E-45 T 10-11-2016 IPR011078 Uncharacterised protein family UPF0001 A4G23_RS06220 9866b26bdcb47683fc16372b4b442af5 242 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 83 97 - T 10-11-2016 IPR011078 Uncharacterised protein family UPF0001 A4G23_RS06220 9866b26bdcb47683fc16372b4b442af5 242 SUPERFAMILY SSF51419 8 236 7.71E-63 T 10-11-2016 IPR029066 PLP-binding barrel A4G23_RS20505 3d039c0f39754fae5ca3a7aa62e43f3f 79 Pfam PF13083 KH domain 3 64 4.2E-19 T 10-11-2016 A4G23_RS20505 3d039c0f39754fae5ca3a7aa62e43f3f 79 Hamap MF_00088 UPF0109 protein . 2 73 21.976 T 10-11-2016 IPR020627 Uncharacterised protein family UPF0109 A4G23_RS20505 3d039c0f39754fae5ca3a7aa62e43f3f 79 Gene3D G3DSA:3.30.300.120 5 63 9.9E-6 T 10-11-2016 A4G23_RS20505 3d039c0f39754fae5ca3a7aa62e43f3f 79 SUPERFAMILY SSF54814 16 62 2.55E-8 T 10-11-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 A4G23_RS11620 f629e93492032c0c672455bdff499fca 343 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 122 322 6.1E-8 T 10-11-2016 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 A4G23_RS11620 f629e93492032c0c672455bdff499fca 343 PIRSF PIRSF019543 11 343 6.8E-56 T 10-11-2016 IPR014503 Clavaminate synthase GO:0005506|GO:0017000|GO:0033758|GO:0055114 A4G23_RS11620 f629e93492032c0c672455bdff499fca 343 SUPERFAMILY SSF51197 41 337 1.19E-42 T 10-11-2016 A4G23_RS11620 f629e93492032c0c672455bdff499fca 343 Gene3D G3DSA:3.60.130.10 38 340 4.5E-46 T 10-11-2016 A4G23_RS23260 9e77d35da892c1be1a96a1ef6c4780fc 383 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 107 341 1.6E-43 T 10-11-2016 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 A4G23_RS23260 9e77d35da892c1be1a96a1ef6c4780fc 383 Gene3D G3DSA:1.10.40.50 290 352 1.6E-22 T 10-11-2016 A4G23_RS23260 9e77d35da892c1be1a96a1ef6c4780fc 383 SUPERFAMILY SSF52540 127 346 1.15E-47 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS23260 9e77d35da892c1be1a96a1ef6c4780fc 383 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 50 348 31.023 T 10-11-2016 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 A4G23_RS23260 9e77d35da892c1be1a96a1ef6c4780fc 383 Gene3D G3DSA:3.40.50.300 127 282 1.2E-40 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS23260 9e77d35da892c1be1a96a1ef6c4780fc 383 Pfam PF03193 Protein of unknown function, DUF258 109 284 2.2E-44 T 10-11-2016 IPR010914 RsgA type GTPase domain GO:0003924|GO:0005525 A4G23_RS08125 8fc7a48a0c867c40fcca517c97ceb7d5 478 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 356 429 1.3E-29 T 10-11-2016 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 A4G23_RS08125 8fc7a48a0c867c40fcca517c97ceb7d5 478 SUPERFAMILY SSF102741 354 430 8.76E-22 T 10-11-2016 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 A4G23_RS08125 8fc7a48a0c867c40fcca517c97ceb7d5 478 Hamap MF_01454 GTPase Obg [obg]. 3 330 44.079 T 10-11-2016 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 A4G23_RS08125 8fc7a48a0c867c40fcca517c97ceb7d5 478 Gene3D G3DSA:3.40.50.300 160 344 1.4E-48 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS08125 8fc7a48a0c867c40fcca517c97ceb7d5 478 ProSitePatterns PS00905 GTP1/OBG family signature. 212 225 - T 10-11-2016 IPR006074 GTP1/OBG, conserved site GO:0005525 A4G23_RS08125 8fc7a48a0c867c40fcca517c97ceb7d5 478 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 4 329 1.2E-125 T 10-11-2016 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 A4G23_RS08125 8fc7a48a0c867c40fcca517c97ceb7d5 478 Pfam PF09269 Domain of unknown function (DUF1967) 356 428 3.8E-26 T 10-11-2016 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 A4G23_RS08125 8fc7a48a0c867c40fcca517c97ceb7d5 478 Pfam PF01018 GTP1/OBG 4 157 5.9E-53 T 10-11-2016 IPR006169 GTP1/OBG domain GO:0005525 A4G23_RS08125 8fc7a48a0c867c40fcca517c97ceb7d5 478 Pfam PF01926 50S ribosome-binding GTPase 161 283 2.0E-22 T 10-11-2016 IPR006073 GTP binding domain GO:0005525 A4G23_RS08125 8fc7a48a0c867c40fcca517c97ceb7d5 478 SUPERFAMILY SSF82051 4 157 7.19E-48 T 10-11-2016 IPR006169 GTP1/OBG domain GO:0005525 A4G23_RS08125 8fc7a48a0c867c40fcca517c97ceb7d5 478 SUPERFAMILY SSF52540 161 337 1.21E-47 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS08125 8fc7a48a0c867c40fcca517c97ceb7d5 478 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 227 245 3.9E-35 T 10-11-2016 IPR006073 GTP binding domain GO:0005525 A4G23_RS08125 8fc7a48a0c867c40fcca517c97ceb7d5 478 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 3.9E-35 T 10-11-2016 IPR006073 GTP binding domain GO:0005525 A4G23_RS08125 8fc7a48a0c867c40fcca517c97ceb7d5 478 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 3.9E-35 T 10-11-2016 IPR006073 GTP binding domain GO:0005525 A4G23_RS08125 8fc7a48a0c867c40fcca517c97ceb7d5 478 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 210 225 3.9E-35 T 10-11-2016 IPR006073 GTP binding domain GO:0005525 A4G23_RS08125 8fc7a48a0c867c40fcca517c97ceb7d5 478 Gene3D G3DSA:2.70.210.12 3 156 1.5E-49 T 10-11-2016 IPR006169 GTP1/OBG domain GO:0005525 A4G23_RS10260 8d638c9952dc9b6390740afb99dd6216 131 Pfam PF03259 Roadblock/LC7 domain 10 96 1.7E-15 T 10-11-2016 IPR004942 Roadblock/LAMTOR2 domain A4G23_RS10260 8d638c9952dc9b6390740afb99dd6216 131 SMART SM00960 8 96 8.1E-17 T 10-11-2016 IPR004942 Roadblock/LAMTOR2 domain A4G23_RS10260 8d638c9952dc9b6390740afb99dd6216 131 Gene3D G3DSA:3.30.450.30 9 121 4.0E-29 T 10-11-2016 A4G23_RS10260 8d638c9952dc9b6390740afb99dd6216 131 SUPERFAMILY SSF103196 10 121 2.79E-22 T 10-11-2016 A4G23_RS24935 b5bc27aa888185a15ef25e0c091eff91 270 Gene3D G3DSA:3.90.190.10 16 101 6.4E-20 T 10-11-2016 IPR029021 Protein-tyrosine phosphatase-like A4G23_RS24935 b5bc27aa888185a15ef25e0c091eff91 270 Gene3D G3DSA:3.90.190.10 136 194 6.4E-20 T 10-11-2016 IPR029021 Protein-tyrosine phosphatase-like A4G23_RS24935 b5bc27aa888185a15ef25e0c091eff91 270 SUPERFAMILY SSF52799 15 268 1.12E-51 T 10-11-2016 IPR029021 Protein-tyrosine phosphatase-like A4G23_RS24935 b5bc27aa888185a15ef25e0c091eff91 270 Pfam PF13350 Tyrosine phosphatase family 15 268 6.3E-64 T 10-11-2016 IPR026893 Tyrosine/serine-protein phosphatase IphP-type A4G23_RS24300 1adc8d3bb7c63c55be6861c7b301ef38 594 Gene3D G3DSA:3.40.50.720 3 189 1.4E-52 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS24300 1adc8d3bb7c63c55be6861c7b301ef38 594 Gene3D G3DSA:3.40.50.720 308 496 4.9E-53 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS24300 1adc8d3bb7c63c55be6861c7b301ef38 594 SUPERFAMILY SSF48179 495 592 2.38E-28 T 10-11-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A4G23_RS24300 1adc8d3bb7c63c55be6861c7b301ef38 594 SUPERFAMILY SSF51735 310 492 1.43E-51 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS24300 1adc8d3bb7c63c55be6861c7b301ef38 594 Gene3D G3DSA:1.10.1040.10 190 284 1.5E-28 T 10-11-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A4G23_RS24300 1adc8d3bb7c63c55be6861c7b301ef38 594 Gene3D G3DSA:1.10.1040.10 497 591 2.2E-31 T 10-11-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A4G23_RS24300 1adc8d3bb7c63c55be6861c7b301ef38 594 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 315 492 1.1E-57 T 10-11-2016 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 A4G23_RS24300 1adc8d3bb7c63c55be6861c7b301ef38 594 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 7 185 1.3E-59 T 10-11-2016 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 A4G23_RS24300 1adc8d3bb7c63c55be6861c7b301ef38 594 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 188 284 4.5E-29 T 10-11-2016 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 A4G23_RS24300 1adc8d3bb7c63c55be6861c7b301ef38 594 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 495 591 1.3E-32 T 10-11-2016 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 A4G23_RS24300 1adc8d3bb7c63c55be6861c7b301ef38 594 SUPERFAMILY SSF51735 6 187 1.17E-50 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS24300 1adc8d3bb7c63c55be6861c7b301ef38 594 SUPERFAMILY SSF48179 187 289 1.28E-27 T 10-11-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A4G23_RS04605 678b1cf7c98d233e16ec2bed79f3c283 575 SUPERFAMILY SSF52402 415 540 9.08E-24 T 10-11-2016 A4G23_RS04605 678b1cf7c98d233e16ec2bed79f3c283 575 SUPERFAMILY SSF52402 169 315 9.08E-24 T 10-11-2016 A4G23_RS04605 678b1cf7c98d233e16ec2bed79f3c283 575 Pfam PF00733 Asparagine synthase 179 543 1.2E-25 T 10-11-2016 IPR001962 Asparagine synthase GO:0004066|GO:0006529 A4G23_RS04605 678b1cf7c98d233e16ec2bed79f3c283 575 Gene3D G3DSA:3.60.20.10 60 154 1.4E-5 T 10-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal A4G23_RS04605 678b1cf7c98d233e16ec2bed79f3c283 575 Gene3D G3DSA:3.40.50.620 410 558 4.9E-22 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS04605 678b1cf7c98d233e16ec2bed79f3c283 575 Gene3D G3DSA:3.40.50.620 169 311 4.9E-22 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS09125 a4143bf8227806ff9c4d09ba94a0a63a 577 Gene3D G3DSA:2.60.40.290 44 146 2.4E-39 T 10-11-2016 IPR012291 Cellulose-binding family II/chitobiase, carbohydrate-binding domain GO:0004553|GO:0030247 A4G23_RS09125 a4143bf8227806ff9c4d09ba94a0a63a 577 SMART SM00637 45 144 1.1E-49 T 10-11-2016 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 A4G23_RS09125 a4143bf8227806ff9c4d09ba94a0a63a 577 Gene3D G3DSA:3.20.20.40 162 577 1.1E-117 T 10-11-2016 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 A4G23_RS09125 a4143bf8227806ff9c4d09ba94a0a63a 577 PRINTS PR00733 Glycosyl hydrolase family 6 signature 376 386 2.9E-37 T 10-11-2016 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 A4G23_RS09125 a4143bf8227806ff9c4d09ba94a0a63a 577 PRINTS PR00733 Glycosyl hydrolase family 6 signature 182 201 2.9E-37 T 10-11-2016 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 A4G23_RS09125 a4143bf8227806ff9c4d09ba94a0a63a 577 PRINTS PR00733 Glycosyl hydrolase family 6 signature 264 279 2.9E-37 T 10-11-2016 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 A4G23_RS09125 a4143bf8227806ff9c4d09ba94a0a63a 577 PRINTS PR00733 Glycosyl hydrolase family 6 signature 503 517 2.9E-37 T 10-11-2016 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 A4G23_RS09125 a4143bf8227806ff9c4d09ba94a0a63a 577 PRINTS PR00733 Glycosyl hydrolase family 6 signature 480 500 2.9E-37 T 10-11-2016 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 A4G23_RS09125 a4143bf8227806ff9c4d09ba94a0a63a 577 PRINTS PR00733 Glycosyl hydrolase family 6 signature 439 452 2.9E-37 T 10-11-2016 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 A4G23_RS09125 a4143bf8227806ff9c4d09ba94a0a63a 577 PRINTS PR00733 Glycosyl hydrolase family 6 signature 336 349 2.9E-37 T 10-11-2016 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 A4G23_RS09125 a4143bf8227806ff9c4d09ba94a0a63a 577 PRINTS PR00733 Glycosyl hydrolase family 6 signature 232 245 2.9E-37 T 10-11-2016 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 A4G23_RS09125 a4143bf8227806ff9c4d09ba94a0a63a 577 ProSitePatterns PS00655 Glycosyl hydrolases family 6 signature 1. 237 253 - T 10-11-2016 IPR001524 Glycoside hydrolase, family 6, conserved site GO:0004553|GO:0005975 A4G23_RS09125 a4143bf8227806ff9c4d09ba94a0a63a 577 PIRSF PIRSF001100 18 577 1.5E-106 T 10-11-2016 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 A4G23_RS09125 a4143bf8227806ff9c4d09ba94a0a63a 577 SUPERFAMILY SSF49384 42 146 1.95E-34 T 10-11-2016 IPR008965 Carbohydrate-binding domain GO:0030246 A4G23_RS09125 a4143bf8227806ff9c4d09ba94a0a63a 577 SUPERFAMILY SSF51989 164 577 1.7E-102 T 10-11-2016 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 A4G23_RS09125 a4143bf8227806ff9c4d09ba94a0a63a 577 Pfam PF01341 Glycosyl hydrolases family 6 183 526 3.3E-93 T 10-11-2016 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 A4G23_RS09125 a4143bf8227806ff9c4d09ba94a0a63a 577 Pfam PF00553 Cellulose binding domain 45 144 2.0E-33 T 10-11-2016 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 A4G23_RS09125 a4143bf8227806ff9c4d09ba94a0a63a 577 ProSitePatterns PS00561 CBM2a (carbohydrate-binding type-2) domain signature. 109 122 - T 10-11-2016 IPR018366 Carbohydrate-binding type-2, conserved site GO:0004553|GO:0005975|GO:0030246 A4G23_RS05540 5f889768a35345f75a08ab728ad04ce3 327 Gene3D G3DSA:3.30.60.70 119 159 8.3E-14 T 10-11-2016 IPR032784 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, middle domain KEGG: 00300+2.3.1.117 A4G23_RS05540 5f889768a35345f75a08ab728ad04ce3 327 Hamap MF_02122 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 7 324 43.83 T 10-11-2016 IPR026586 Type 2 tetrahydrodipicolinate N-succinyltransferase family GO:0008666 KEGG: 00300+2.3.1.117 A4G23_RS05540 5f889768a35345f75a08ab728ad04ce3 327 Gene3D G3DSA:2.160.10.10 160 314 5.9E-33 T 10-11-2016 A4G23_RS05540 5f889768a35345f75a08ab728ad04ce3 327 SUPERFAMILY SSF51161 79 307 5.82E-39 T 10-11-2016 IPR011004 Trimeric LpxA-like A4G23_RS05540 5f889768a35345f75a08ab728ad04ce3 327 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 241 273 9.8E-14 T 10-11-2016 IPR001451 Hexapeptide repeat A4G23_RS05540 5f889768a35345f75a08ab728ad04ce3 327 TIGRFAM TIGR03535 DapD_actino: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 9 326 3.7E-153 T 10-11-2016 IPR019875 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, actinobacteria KEGG: 00300+2.3.1.117 A4G23_RS05540 5f889768a35345f75a08ab728ad04ce3 327 Pfam PF14789 Tetrahydrodipicolinate N-succinyltransferase middle 119 159 1.8E-17 T 10-11-2016 IPR032784 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, middle domain KEGG: 00300+2.3.1.117 A4G23_RS06945 0569e9578c3f8196697daba816f6acef 310 Gene3D G3DSA:3.60.10.10 96 247 2.1E-8 T 10-11-2016 IPR005135 Endonuclease/exonuclease/phosphatase A4G23_RS06945 0569e9578c3f8196697daba816f6acef 310 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 99 301 1.6E-18 T 10-11-2016 IPR005135 Endonuclease/exonuclease/phosphatase A4G23_RS06945 0569e9578c3f8196697daba816f6acef 310 SUPERFAMILY SSF56219 94 309 6.94E-28 T 10-11-2016 IPR005135 Endonuclease/exonuclease/phosphatase A4G23_RS13360 c42bf895654ef94fd99b8d85318aeec1 512 SUPERFAMILY SSF63817 352 498 3.14E-29 T 10-11-2016 IPR023365 Sortase domain A4G23_RS13360 c42bf895654ef94fd99b8d85318aeec1 512 Gene3D G3DSA:2.40.260.10 354 500 2.8E-28 T 10-11-2016 IPR023365 Sortase domain A4G23_RS13360 c42bf895654ef94fd99b8d85318aeec1 512 TIGRFAM TIGR01076 sortase_fam: sortase 359 498 1.3E-15 T 10-11-2016 IPR005754 Sortase family A4G23_RS13360 c42bf895654ef94fd99b8d85318aeec1 512 Pfam PF04203 Sortase family 360 497 3.7E-27 T 10-11-2016 IPR005754 Sortase family A4G23_RS26140 9973e21728bfc5274f9ecc8790865409 330 SUPERFAMILY SSF161098 102 310 1.7E-12 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS26140 9973e21728bfc5274f9ecc8790865409 330 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 125 326 2.9E-37 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS26140 9973e21728bfc5274f9ecc8790865409 330 Gene3D G3DSA:1.10.3720.10 100 319 5.2E-15 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS02040 d2866e2bf23a88a577068d0bba90e60f 410 Gene3D G3DSA:1.10.10.10 337 387 1.1E-4 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS01485 d2a2d6ef5f665556fd4035d19e683151 67 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 65 19.347 T 10-11-2016 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 A4G23_RS01485 d2a2d6ef5f665556fd4035d19e683151 67 Pfam PF02416 mttA/Hcf106 family 5 56 1.2E-16 T 10-11-2016 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 A4G23_RS01485 d2a2d6ef5f665556fd4035d19e683151 67 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 4 48 3.6E-18 T 10-11-2016 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 A4G23_RS01430 451d287a1a19c4d8908a965ed497cebc 459 SMART SM00028 358 391 31.0 T 10-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 A4G23_RS01430 451d287a1a19c4d8908a965ed497cebc 459 SMART SM00028 317 350 180.0 T 10-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 A4G23_RS01430 451d287a1a19c4d8908a965ed497cebc 459 SMART SM00028 116 149 69.0 T 10-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 A4G23_RS01430 451d287a1a19c4d8908a965ed497cebc 459 SMART SM00028 398 431 21.0 T 10-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 A4G23_RS01430 451d287a1a19c4d8908a965ed497cebc 459 SMART SM00028 237 270 500.0 T 10-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 A4G23_RS01430 451d287a1a19c4d8908a965ed497cebc 459 SUPERFAMILY SSF48452 85 184 4.17E-7 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS01430 451d287a1a19c4d8908a965ed497cebc 459 Pfam PF01381 Helix-turn-helix 12 64 1.6E-5 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS01430 451d287a1a19c4d8908a965ed497cebc 459 SUPERFAMILY SSF47413 5 67 1.38E-10 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS01430 451d287a1a19c4d8908a965ed497cebc 459 Gene3D G3DSA:1.25.40.10 125 183 2.9E-5 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS01430 451d287a1a19c4d8908a965ed497cebc 459 Gene3D G3DSA:1.25.40.10 207 423 8.4E-15 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS01430 451d287a1a19c4d8908a965ed497cebc 459 SUPERFAMILY SSF48452 316 426 2.74E-11 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS01430 451d287a1a19c4d8908a965ed497cebc 459 SMART SM00530 10 64 1.9E-6 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS01430 451d287a1a19c4d8908a965ed497cebc 459 SUPERFAMILY SSF48452 159 310 4.0E-7 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS01430 451d287a1a19c4d8908a965ed497cebc 459 Pfam PF13432 Tetratricopeptide repeat 323 386 0.0047 T 10-11-2016 A4G23_RS01430 451d287a1a19c4d8908a965ed497cebc 459 Pfam PF13432 Tetratricopeptide repeat 87 150 7.9E-6 T 10-11-2016 A4G23_RS01430 451d287a1a19c4d8908a965ed497cebc 459 Gene3D G3DSA:1.10.260.40 6 68 1.8E-11 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS01430 451d287a1a19c4d8908a965ed497cebc 459 Gene3D G3DSA:1.25.40.10 71 124 6.4E-5 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS05510 60400f81928ee9d0ced9294e0b25f936 249 SUPERFAMILY SSF54909 41 101 1.07E-10 T 10-11-2016 IPR011008 Dimeric alpha-beta barrel A4G23_RS05510 60400f81928ee9d0ced9294e0b25f936 249 SUPERFAMILY SSF54909 144 227 1.69E-9 T 10-11-2016 IPR011008 Dimeric alpha-beta barrel A4G23_RS05510 60400f81928ee9d0ced9294e0b25f936 249 Gene3D G3DSA:3.30.70.900 28 128 2.1E-25 T 10-11-2016 A4G23_RS05510 60400f81928ee9d0ced9294e0b25f936 249 Gene3D G3DSA:3.30.70.900 139 244 3.5E-29 T 10-11-2016 A4G23_RS05510 60400f81928ee9d0ced9294e0b25f936 249 Pfam PF03992 Antibiotic biosynthesis monooxygenase 42 100 1.0E-5 T 10-11-2016 IPR007138 Antibiotic biosynthesis monooxygenase domain A4G23_RS05510 60400f81928ee9d0ced9294e0b25f936 249 Pfam PF03992 Antibiotic biosynthesis monooxygenase 143 211 1.9E-10 T 10-11-2016 IPR007138 Antibiotic biosynthesis monooxygenase domain A4G23_RS26695 b67109e88deacddc264827f297152a4e 361 Gene3D G3DSA:3.90.180.10 2 182 1.9E-56 T 10-11-2016 IPR011032 GroES-like A4G23_RS26695 b67109e88deacddc264827f297152a4e 361 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 148 2.6E-27 T 10-11-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A4G23_RS26695 b67109e88deacddc264827f297152a4e 361 TIGRFAM TIGR03451 mycoS_dep_FDH: S-(hydroxymethyl)mycothiol dehydrogenase 5 361 8.5E-210 T 10-11-2016 IPR017816 S-(hydroxymethyl)mycothiol dehydrogenase KEGG: 00072+1.1.1.30|KEGG: 00650+1.1.1.30 A4G23_RS26695 b67109e88deacddc264827f297152a4e 361 Gene3D G3DSA:3.40.50.720 183 302 1.1E-42 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS26695 b67109e88deacddc264827f297152a4e 361 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 10-11-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 A4G23_RS26695 b67109e88deacddc264827f297152a4e 361 SMART SM00829 12 361 1.5E-4 T 10-11-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A4G23_RS26695 b67109e88deacddc264827f297152a4e 361 SUPERFAMILY SSF50129 4 186 7.15E-56 T 10-11-2016 IPR011032 GroES-like A4G23_RS26695 b67109e88deacddc264827f297152a4e 361 SUPERFAMILY SSF50129 310 360 2.26E-7 T 10-11-2016 IPR011032 GroES-like A4G23_RS26695 b67109e88deacddc264827f297152a4e 361 SUPERFAMILY SSF51735 152 326 5.26E-45 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS26695 b67109e88deacddc264827f297152a4e 361 Pfam PF00107 Zinc-binding dehydrogenase 190 316 2.4E-29 T 10-11-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A4G23_RS00570 333d53ed6f30c2ea039d9c57038ee576 344 Gene3D G3DSA:3.40.50.720 8 321 8.3E-41 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS00570 333d53ed6f30c2ea039d9c57038ee576 344 SUPERFAMILY SSF51735 6 328 1.88E-47 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS00570 333d53ed6f30c2ea039d9c57038ee576 344 Pfam PF01370 NAD dependent epimerase/dehydratase family 9 242 6.3E-20 T 10-11-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 A4G23_RS15880 a8d76effac08de085a0a82f46bdd81c2 281 TIGRFAM TIGR01475 ubiA_other: putative 4-hydroxybenzoate polyprenyltransferase 2 273 2.0E-84 T 10-11-2016 IPR006371 4-hydroxybenzoate polyprenyltransferase-related A4G23_RS15880 a8d76effac08de085a0a82f46bdd81c2 281 Pfam PF01040 UbiA prenyltransferase family 15 257 2.7E-51 T 10-11-2016 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 A4G23_RS00830 e3808d0e600ae240a862a4d11bd75f32 470 Pfam PF00557 Metallopeptidase family M24 206 445 6.5E-48 T 10-11-2016 IPR000994 Peptidase M24, structural domain A4G23_RS00830 e3808d0e600ae240a862a4d11bd75f32 470 Gene3D G3DSA:3.40.350.10 32 204 4.8E-28 T 10-11-2016 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A4G23_RS00830 e3808d0e600ae240a862a4d11bd75f32 470 Pfam PF05195 Aminopeptidase P, N-terminal domain 35 153 1.9E-15 T 10-11-2016 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 A4G23_RS00830 e3808d0e600ae240a862a4d11bd75f32 470 SUPERFAMILY SSF53092 32 200 2.56E-20 T 10-11-2016 IPR028980 Creatinase/Aminopeptidase P, N-terminal A4G23_RS00830 e3808d0e600ae240a862a4d11bd75f32 470 SMART SM01011 28 176 3.8E-23 T 10-11-2016 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 A4G23_RS00830 e3808d0e600ae240a862a4d11bd75f32 470 SUPERFAMILY SSF55920 203 466 9.94E-63 T 10-11-2016 IPR000994 Peptidase M24, structural domain A4G23_RS00830 e3808d0e600ae240a862a4d11bd75f32 470 Gene3D G3DSA:3.90.230.10 205 457 8.5E-61 T 10-11-2016 IPR000994 Peptidase M24, structural domain A4G23_RS20600 2f431c43b95bcb883004a231d5dc9b89 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 10 185 3.1E-62 T 10-11-2016 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 A4G23_RS20600 2f431c43b95bcb883004a231d5dc9b89 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 26.645 T 10-11-2016 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 A4G23_RS20600 2f431c43b95bcb883004a231d5dc9b89 185 Pfam PF01765 Ribosome recycling factor 21 183 2.0E-57 T 10-11-2016 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 A4G23_RS20600 2f431c43b95bcb883004a231d5dc9b89 185 SUPERFAMILY SSF55194 3 184 1.96E-66 T 10-11-2016 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 A4G23_RS20600 2f431c43b95bcb883004a231d5dc9b89 185 Gene3D G3DSA:1.10.132.20 66 185 2.1E-40 T 10-11-2016 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 A4G23_RS19665 ef0e51b7a0cd2b3c42168d93595ea6e0 314 SUPERFAMILY SSF52540 2 225 2.66E-56 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS19665 ef0e51b7a0cd2b3c42168d93595ea6e0 314 Gene3D G3DSA:3.40.50.300 1 226 3.0E-59 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS19665 ef0e51b7a0cd2b3c42168d93595ea6e0 314 Pfam PF00005 ABC transporter 18 156 1.5E-26 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS19665 ef0e51b7a0cd2b3c42168d93595ea6e0 314 SMART SM00382 26 204 2.6E-8 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS06530 8bbb7d6213533e03f992ff2b336d337d 354 Gene3D G3DSA:3.40.1030.10 86 353 1.5E-103 T 10-11-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A4G23_RS06530 8bbb7d6213533e03f992ff2b336d337d 354 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 19 351 35.105 T 10-11-2016 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 A4G23_RS06530 8bbb7d6213533e03f992ff2b336d337d 354 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 22 350 2.3E-108 T 10-11-2016 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 A4G23_RS06530 8bbb7d6213533e03f992ff2b336d337d 354 SUPERFAMILY SSF52418 87 353 1.44E-83 T 10-11-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A4G23_RS06530 8bbb7d6213533e03f992ff2b336d337d 354 Pfam PF02885 Glycosyl transferase family, helical bundle domain 21 80 1.2E-17 T 10-11-2016 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 A4G23_RS06530 8bbb7d6213533e03f992ff2b336d337d 354 SUPERFAMILY SSF47648 16 83 4.71E-19 T 10-11-2016 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 A4G23_RS06530 8bbb7d6213533e03f992ff2b336d337d 354 Gene3D G3DSA:1.20.970.10 16 80 1.6E-23 T 10-11-2016 A4G23_RS06530 8bbb7d6213533e03f992ff2b336d337d 354 Pfam PF00591 Glycosyl transferase family, a/b domain 89 341 1.8E-80 T 10-11-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A4G23_RS27100 c7d1ac72be7e877418192688d44f0b9c 195 Pfam PF04862 Protein of unknown function (DUF642) 34 187 1.7E-26 T 10-11-2016 IPR006946 Domain of unknown function DUF642 A4G23_RS27100 c7d1ac72be7e877418192688d44f0b9c 195 TIGRFAM TIGR04362 choice_anch_C: choice-of-anchor C domain 34 187 1.9E-47 T 10-11-2016 IPR027576 Choice-of-anchor C domain A4G23_RS02560 5be0e7795a0b0f311dbd33830daaab3a 166 Gene3D G3DSA:3.90.1720.10 47 156 1.4E-38 T 10-11-2016 IPR000064 Endopeptidase, NLPC/P60 domain A4G23_RS02560 5be0e7795a0b0f311dbd33830daaab3a 166 SUPERFAMILY SSF54001 49 156 1.13E-35 T 10-11-2016 A4G23_RS02560 5be0e7795a0b0f311dbd33830daaab3a 166 Pfam PF00877 NlpC/P60 family 65 147 3.5E-25 T 10-11-2016 IPR000064 Endopeptidase, NLPC/P60 domain A4G23_RS15325 3dd85c85e2fe9d45656f476b9504d6a5 227 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 46 208 7.3E-23 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS15325 3dd85c85e2fe9d45656f476b9504d6a5 227 Gene3D G3DSA:1.10.3720.10 21 204 1.6E-28 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS15325 3dd85c85e2fe9d45656f476b9504d6a5 227 SUPERFAMILY SSF161098 22 205 2.09E-34 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS26735 50813822ec92906e2d1878f91f31e93a 394 Gene3D G3DSA:3.60.150.10 4 390 9.5E-153 T 10-11-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A4G23_RS26735 50813822ec92906e2d1878f91f31e93a 394 Pfam PF01264 Chorismate synthase 4 368 2.3E-117 T 10-11-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A4G23_RS26735 50813822ec92906e2d1878f91f31e93a 394 ProSitePatterns PS00787 Chorismate synthase signature 1. 10 25 - T 10-11-2016 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A4G23_RS26735 50813822ec92906e2d1878f91f31e93a 394 ProSitePatterns PS00789 Chorismate synthase signature 3. 343 359 - T 10-11-2016 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A4G23_RS26735 50813822ec92906e2d1878f91f31e93a 394 ProSitePatterns PS00788 Chorismate synthase signature 2. 136 152 - T 10-11-2016 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A4G23_RS26735 50813822ec92906e2d1878f91f31e93a 394 TIGRFAM TIGR00033 aroC: chorismate synthase 4 374 1.5E-135 T 10-11-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A4G23_RS26735 50813822ec92906e2d1878f91f31e93a 394 PIRSF PIRSF001456 1 387 1.3E-126 T 10-11-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A4G23_RS26735 50813822ec92906e2d1878f91f31e93a 394 Hamap MF_00300 Chorismate synthase [aroC]. 4 376 34.458 T 10-11-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A4G23_RS26735 50813822ec92906e2d1878f91f31e93a 394 SUPERFAMILY SSF103263 3 391 1.57E-136 T 10-11-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A4G23_RS07280 45b92a9c4428e080f54e0518e37f6126 209 Pfam PF09335 SNARE associated Golgi protein 32 163 8.7E-9 T 10-11-2016 IPR032816 SNARE associated Golgi protein A4G23_RS21625 3577bdffa964f01dc2a7045c2e8b5f81 457 SUPERFAMILY SSF52777 199 436 3.0E-62 T 10-11-2016 A4G23_RS21625 3577bdffa964f01dc2a7045c2e8b5f81 457 SUPERFAMILY SSF52777 10 209 5.34E-44 T 10-11-2016 A4G23_RS21625 3577bdffa964f01dc2a7045c2e8b5f81 457 Pfam PF13745 HxxPF-repeated domain 332 419 2.6E-29 T 10-11-2016 A4G23_RS21625 3577bdffa964f01dc2a7045c2e8b5f81 457 Pfam PF00668 Condensation domain 10 307 3.8E-66 T 10-11-2016 IPR001242 Condensation domain A4G23_RS08270 057429a9d81f538c4d0560126938f1db 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 43 61 2.4E-62 T 10-11-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 A4G23_RS08270 057429a9d81f538c4d0560126938f1db 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 181 201 2.4E-62 T 10-11-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 A4G23_RS08270 057429a9d81f538c4d0560126938f1db 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 294 320 2.4E-62 T 10-11-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 A4G23_RS08270 057429a9d81f538c4d0560126938f1db 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 63 86 2.4E-62 T 10-11-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 A4G23_RS08270 057429a9d81f538c4d0560126938f1db 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 126 145 2.4E-62 T 10-11-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 A4G23_RS08270 057429a9d81f538c4d0560126938f1db 339 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 6 330 7.4E-153 T 10-11-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 A4G23_RS08270 057429a9d81f538c4d0560126938f1db 339 Gene3D G3DSA:3.90.640.10 181 253 1.0E-31 T 10-11-2016 A4G23_RS08270 057429a9d81f538c4d0560126938f1db 339 SUPERFAMILY SSF53067 144 322 7.78E-51 T 10-11-2016 A4G23_RS08270 057429a9d81f538c4d0560126938f1db 339 Gene3D G3DSA:3.30.420.40 154 180 5.5E-36 T 10-11-2016 A4G23_RS08270 057429a9d81f538c4d0560126938f1db 339 Gene3D G3DSA:3.30.420.40 257 311 5.5E-36 T 10-11-2016 A4G23_RS08270 057429a9d81f538c4d0560126938f1db 339 Gene3D G3DSA:3.30.420.40 6 153 5.5E-48 T 10-11-2016 A4G23_RS08270 057429a9d81f538c4d0560126938f1db 339 Pfam PF06723 MreB/Mbl protein 6 330 1.5E-155 T 10-11-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 A4G23_RS08270 057429a9d81f538c4d0560126938f1db 339 SUPERFAMILY SSF53067 5 142 1.58E-42 T 10-11-2016 A4G23_RS23705 df06de1b27a5fbe87f973c89cc81de93 295 Gene3D G3DSA:3.40.50.620 5 141 5.6E-28 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS23705 df06de1b27a5fbe87f973c89cc81de93 295 Gene3D G3DSA:3.40.50.620 145 289 2.1E-37 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS23705 df06de1b27a5fbe87f973c89cc81de93 295 Pfam PF00582 Universal stress protein family 5 141 4.5E-24 T 10-11-2016 IPR006016 UspA GO:0006950 A4G23_RS23705 df06de1b27a5fbe87f973c89cc81de93 295 Pfam PF00582 Universal stress protein family 150 289 8.8E-29 T 10-11-2016 IPR006016 UspA GO:0006950 A4G23_RS23705 df06de1b27a5fbe87f973c89cc81de93 295 SUPERFAMILY SSF52402 149 290 1.76E-32 T 10-11-2016 A4G23_RS23705 df06de1b27a5fbe87f973c89cc81de93 295 PRINTS PR01438 Universal stress protein signature 267 289 4.7E-16 T 10-11-2016 IPR006015 Universal stress protein A A4G23_RS23705 df06de1b27a5fbe87f973c89cc81de93 295 PRINTS PR01438 Universal stress protein signature 249 261 4.7E-16 T 10-11-2016 IPR006015 Universal stress protein A A4G23_RS23705 df06de1b27a5fbe87f973c89cc81de93 295 PRINTS PR01438 Universal stress protein signature 147 165 4.7E-16 T 10-11-2016 IPR006015 Universal stress protein A A4G23_RS23705 df06de1b27a5fbe87f973c89cc81de93 295 SUPERFAMILY SSF52402 5 143 5.11E-29 T 10-11-2016 A4G23_RS23245 02e88c5ff27c099397f8da0578f1df38 414 Gene3D G3DSA:3.40.640.10 47 282 1.6E-50 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS23245 02e88c5ff27c099397f8da0578f1df38 414 SUPERFAMILY SSF53383 20 405 1.24E-72 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS23245 02e88c5ff27c099397f8da0578f1df38 414 Pfam PF00266 Aminotransferase class-V 37 398 2.0E-65 T 10-11-2016 IPR000192 Aminotransferase class V domain A4G23_RS23245 02e88c5ff27c099397f8da0578f1df38 414 Gene3D G3DSA:3.90.1150.10 283 406 4.9E-21 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS23245 02e88c5ff27c099397f8da0578f1df38 414 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 238 257 - T 10-11-2016 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site A4G23_RS11250 c7b81446771fa617f2998fa8e3792d38 215 Gene3D G3DSA:2.60.120.10 2 187 3.5E-45 T 10-11-2016 IPR014710 RmlC-like jelly roll fold A4G23_RS11250 c7b81446771fa617f2998fa8e3792d38 215 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 7 177 3.9E-38 T 10-11-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 A4G23_RS11250 c7b81446771fa617f2998fa8e3792d38 215 SUPERFAMILY SSF51182 2 190 9.93E-49 T 10-11-2016 IPR011051 RmlC-like cupin domain A4G23_RS11250 c7b81446771fa617f2998fa8e3792d38 215 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 184 4.0E-44 T 10-11-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 A4G23_RS04470 3c07a69ecdeeaae1a970016613f90d65 442 Gene3D G3DSA:3.30.420.40 92 222 1.1E-28 T 10-11-2016 A4G23_RS04470 3c07a69ecdeeaae1a970016613f90d65 442 Gene3D G3DSA:1.10.10.10 17 84 1.5E-17 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS04470 3c07a69ecdeeaae1a970016613f90d65 442 Gene3D G3DSA:3.30.420.40 246 392 8.9E-44 T 10-11-2016 A4G23_RS04470 3c07a69ecdeeaae1a970016613f90d65 442 SUPERFAMILY SSF46785 17 81 4.72E-13 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS04470 3c07a69ecdeeaae1a970016613f90d65 442 SUPERFAMILY SSF53067 247 423 2.21E-37 T 10-11-2016 A4G23_RS04470 3c07a69ecdeeaae1a970016613f90d65 442 Pfam PF00480 ROK family 242 419 1.5E-31 T 10-11-2016 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A4G23_RS04470 3c07a69ecdeeaae1a970016613f90d65 442 SUPERFAMILY SSF53067 92 218 1.35E-14 T 10-11-2016 A4G23_RS26715 690ba2ff529bee08925a756a7a054bdd 169 Pfam PF12833 Helix-turn-helix domain 42 119 4.7E-17 T 10-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4G23_RS26715 690ba2ff529bee08925a756a7a054bdd 169 Gene3D G3DSA:1.10.10.60 75 121 9.2E-11 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS26715 690ba2ff529bee08925a756a7a054bdd 169 SMART SM00342 36 119 1.5E-22 T 10-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4G23_RS26715 690ba2ff529bee08925a756a7a054bdd 169 SUPERFAMILY SSF46689 72 121 9.41E-9 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS26715 690ba2ff529bee08925a756a7a054bdd 169 SUPERFAMILY SSF46689 20 69 1.34E-7 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS26715 690ba2ff529bee08925a756a7a054bdd 169 Gene3D G3DSA:1.10.10.60 20 74 1.1E-13 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS05575 5f977556640af2edc763852cf7162d1e 391 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 110 376 1.3E-75 T 10-11-2016 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 A4G23_RS05575 5f977556640af2edc763852cf7162d1e 391 Pfam PF01458 Uncharacterized protein family (UPF0051) 141 362 3.0E-73 T 10-11-2016 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 A4G23_RS05575 5f977556640af2edc763852cf7162d1e 391 SUPERFAMILY SSF101960 36 388 9.02E-92 T 10-11-2016 A4G23_RS10300 f1b9bf59910147d231db50cabfd812ab 461 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 10-11-2016 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 A4G23_RS10300 f1b9bf59910147d231db50cabfd812ab 461 Gene3D G3DSA:3.10.580.10 333 458 3.1E-20 T 10-11-2016 A4G23_RS10300 f1b9bf59910147d231db50cabfd812ab 461 Pfam PF00571 CBS domain 409 457 7.9E-4 T 10-11-2016 IPR000644 CBS domain A4G23_RS10300 f1b9bf59910147d231db50cabfd812ab 461 Pfam PF00571 CBS domain 336 394 3.7E-5 T 10-11-2016 IPR000644 CBS domain A4G23_RS10300 f1b9bf59910147d231db50cabfd812ab 461 Gene3D G3DSA:3.40.50.1100 153 313 1.4E-73 T 10-11-2016 A4G23_RS10300 f1b9bf59910147d231db50cabfd812ab 461 Gene3D G3DSA:3.40.50.1100 2 42 1.4E-73 T 10-11-2016 A4G23_RS10300 f1b9bf59910147d231db50cabfd812ab 461 SUPERFAMILY SSF54631 325 458 5.18E-16 T 10-11-2016 A4G23_RS10300 f1b9bf59910147d231db50cabfd812ab 461 TIGRFAM TIGR01137 cysta_beta: cystathionine beta-synthase 3 457 5.3E-213 T 10-11-2016 IPR005857 Cystathionine beta-synthase GO:0004122|GO:0005737|GO:0019343 KEGG: 00260+4.2.1.22|KEGG: 00270+4.2.1.22|MetaCyc: PWY-801 A4G23_RS10300 f1b9bf59910147d231db50cabfd812ab 461 SMART SM00116 412 457 5.4 T 10-11-2016 IPR000644 CBS domain A4G23_RS10300 f1b9bf59910147d231db50cabfd812ab 461 SMART SM00116 339 395 1.7 T 10-11-2016 IPR000644 CBS domain A4G23_RS10300 f1b9bf59910147d231db50cabfd812ab 461 Gene3D G3DSA:3.40.50.1100 43 147 1.4E-39 T 10-11-2016 A4G23_RS10300 f1b9bf59910147d231db50cabfd812ab 461 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 10 296 4.2E-73 T 10-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4G23_RS10300 f1b9bf59910147d231db50cabfd812ab 461 SUPERFAMILY SSF53686 2 317 2.75E-100 T 10-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4G23_RS02775 ac57a96aac6d5b0d7f8a2a0b2a9da6e2 302 Pfam PF00892 EamA-like transporter family 7 139 1.0E-10 T 10-11-2016 IPR000620 EamA domain GO:0016020|GO:0016021 A4G23_RS02775 ac57a96aac6d5b0d7f8a2a0b2a9da6e2 302 Pfam PF00892 EamA-like transporter family 164 283 1.8E-7 T 10-11-2016 IPR000620 EamA domain GO:0016020|GO:0016021 A4G23_RS02775 ac57a96aac6d5b0d7f8a2a0b2a9da6e2 302 SUPERFAMILY SSF103481 40 145 3.4E-10 T 10-11-2016 A4G23_RS02775 ac57a96aac6d5b0d7f8a2a0b2a9da6e2 302 SUPERFAMILY SSF103481 197 283 6.67E-8 T 10-11-2016 A4G23_RS12745 f13e72777313ee6308ea17a1517fcd2c 396 Pfam PF01266 FAD dependent oxidoreductase 5 388 4.7E-64 T 10-11-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A4G23_RS12745 f13e72777313ee6308ea17a1517fcd2c 396 SUPERFAMILY SSF51905 3 300 6.47E-44 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS12745 f13e72777313ee6308ea17a1517fcd2c 396 Gene3D G3DSA:3.30.9.10 89 139 1.4E-6 T 10-11-2016 A4G23_RS12745 f13e72777313ee6308ea17a1517fcd2c 396 Gene3D G3DSA:3.50.50.60 4 86 4.6E-29 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS12745 f13e72777313ee6308ea17a1517fcd2c 396 Gene3D G3DSA:3.50.50.60 140 215 4.6E-29 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS02580 0357dfcc2335db3a697af51a03599197 431 SUPERFAMILY SSF53383 10 429 9.64E-119 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS02580 0357dfcc2335db3a697af51a03599197 431 Gene3D G3DSA:3.40.640.10 72 334 1.7E-87 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS02580 0357dfcc2335db3a697af51a03599197 431 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 249 286 - T 10-11-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4G23_RS02580 0357dfcc2335db3a697af51a03599197 431 Hamap MF_00834 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [bioA]. 7 431 49.516 T 10-11-2016 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 A4G23_RS02580 0357dfcc2335db3a697af51a03599197 431 Pfam PF00202 Aminotransferase class-III 33 424 9.0E-117 T 10-11-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4G23_RS02580 0357dfcc2335db3a697af51a03599197 431 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 19 427 6.3E-167 T 10-11-2016 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 A4G23_RS02580 0357dfcc2335db3a697af51a03599197 431 Gene3D G3DSA:3.90.1150.10 10 71 6.6E-50 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS02580 0357dfcc2335db3a697af51a03599197 431 Gene3D G3DSA:3.90.1150.10 339 429 6.6E-50 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS10340 e321dbd32d3d3159e3145032a74b08a9 447 SMART SM00828 Methyltransferase in polyketide synthase (PKS) enzymes. 169 409 5.5E-4 T 10-11-2016 IPR020803 Polyketide synthase, methyltransferase domain A4G23_RS10340 e321dbd32d3d3159e3145032a74b08a9 447 Gene3D G3DSA:3.40.50.150 150 423 3.5E-94 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS10340 e321dbd32d3d3159e3145032a74b08a9 447 SUPERFAMILY SSF53335 160 425 4.6E-78 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS10340 e321dbd32d3d3159e3145032a74b08a9 447 PIRSF PIRSF003085 5 442 1.4E-130 T 10-11-2016 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 A4G23_RS10340 e321dbd32d3d3159e3145032a74b08a9 447 Pfam PF02353 Mycolic acid cyclopropane synthetase 151 421 6.1E-92 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS10190 6a356a39731d9809cdcc3b7d6ea086ad 336 Gene3D G3DSA:3.90.25.10 300 322 1.7E-10 T 10-11-2016 A4G23_RS10190 6a356a39731d9809cdcc3b7d6ea086ad 336 Gene3D G3DSA:3.90.25.10 226 247 1.7E-10 T 10-11-2016 A4G23_RS10190 6a356a39731d9809cdcc3b7d6ea086ad 336 Gene3D G3DSA:3.40.50.720 22 225 1.1E-65 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS10190 6a356a39731d9809cdcc3b7d6ea086ad 336 Pfam PF01370 NAD dependent epimerase/dehydratase family 23 253 3.2E-71 T 10-11-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 A4G23_RS10190 6a356a39731d9809cdcc3b7d6ea086ad 336 SUPERFAMILY SSF51735 21 322 7.55E-76 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS10190 6a356a39731d9809cdcc3b7d6ea086ad 336 Hamap MF_00956 GDP-L-fucose synthase [fcl]. 20 321 48.826 T 10-11-2016 IPR028614 GDP-L-fucose synthase/GDP-L-colitose synthase GO:0009226|GO:0016491 KEGG: 00010+1.1.1.27|KEGG: 00051+1.1.1.271|KEGG: 00270+1.1.1.27|KEGG: 00520+1.1.1.271|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-66|MetaCyc: PWY-6901|Reactome: R-HSA-6787639 A4G23_RS25850 9e885dad185351fed2fa1d0cc09cb9ef 351 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 5 325 6.9E-102 T 10-11-2016 IPR019949 Luciferase family oxidoreductase, group 1 A4G23_RS25850 9e885dad185351fed2fa1d0cc09cb9ef 351 Pfam PF00296 Luciferase-like monooxygenase 5 297 4.3E-36 T 10-11-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4G23_RS25850 9e885dad185351fed2fa1d0cc09cb9ef 351 Gene3D G3DSA:3.20.20.30 4 325 7.0E-74 T 10-11-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4G23_RS25850 9e885dad185351fed2fa1d0cc09cb9ef 351 SUPERFAMILY SSF51679 3 325 5.76E-63 T 10-11-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4G23_RS15575 8c0afc13394644811a1e0b82da93b58c 394 PRINTS PR01270 Histone deacetylase superfamily signature 161 176 2.1E-17 T 10-11-2016 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A4G23_RS15575 8c0afc13394644811a1e0b82da93b58c 394 PRINTS PR01270 Histone deacetylase superfamily signature 128 151 2.1E-17 T 10-11-2016 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A4G23_RS15575 8c0afc13394644811a1e0b82da93b58c 394 PRINTS PR01270 Histone deacetylase superfamily signature 248 258 2.1E-17 T 10-11-2016 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A4G23_RS15575 8c0afc13394644811a1e0b82da93b58c 394 SUPERFAMILY SSF52768 6 351 3.55E-98 T 10-11-2016 A4G23_RS15575 8c0afc13394644811a1e0b82da93b58c 394 Pfam PF00850 Histone deacetylase domain 22 319 2.9E-65 T 10-11-2016 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A4G23_RS15575 8c0afc13394644811a1e0b82da93b58c 394 PRINTS PR01272 Acetoin utilisation ACUC protein signature 313 332 3.4E-8 T 10-11-2016 IPR003085 Acetoin utilization protein AcuC GO:0045149 A4G23_RS15575 8c0afc13394644811a1e0b82da93b58c 394 PRINTS PR01272 Acetoin utilisation ACUC protein signature 16 36 3.4E-8 T 10-11-2016 IPR003085 Acetoin utilization protein AcuC GO:0045149 A4G23_RS15575 8c0afc13394644811a1e0b82da93b58c 394 PRINTS PR01272 Acetoin utilisation ACUC protein signature 84 98 3.4E-8 T 10-11-2016 IPR003085 Acetoin utilization protein AcuC GO:0045149 A4G23_RS15575 8c0afc13394644811a1e0b82da93b58c 394 PRINTS PR01272 Acetoin utilisation ACUC protein signature 105 118 3.4E-8 T 10-11-2016 IPR003085 Acetoin utilization protein AcuC GO:0045149 A4G23_RS15575 8c0afc13394644811a1e0b82da93b58c 394 Gene3D G3DSA:3.40.800.20 4 341 3.6E-85 T 10-11-2016 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A4G23_RS12225 cba8bc89c316d12a51b9ce8241427cea 824 SUPERFAMILY SSF55785 426 555 2.62E-27 T 10-11-2016 IPR000014 PAS domain A4G23_RS12225 cba8bc89c316d12a51b9ce8241427cea 824 SMART SM00331 592 814 2.8E-31 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS12225 cba8bc89c316d12a51b9ce8241427cea 824 SUPERFAMILY SSF55785 312 427 7.2E-21 T 10-11-2016 IPR000014 PAS domain A4G23_RS12225 cba8bc89c316d12a51b9ce8241427cea 824 SMART SM00086 517 557 0.0089 T 10-11-2016 IPR001610 PAC motif A4G23_RS12225 cba8bc89c316d12a51b9ce8241427cea 824 SMART SM00086 388 429 11.0 T 10-11-2016 IPR001610 PAC motif A4G23_RS12225 cba8bc89c316d12a51b9ce8241427cea 824 Gene3D G3DSA:3.30.450.20 313 427 1.2E-24 T 10-11-2016 A4G23_RS12225 cba8bc89c316d12a51b9ce8241427cea 824 Pfam PF08448 PAS fold 323 430 1.5E-21 T 10-11-2016 IPR013656 PAS fold-4 A4G23_RS12225 cba8bc89c316d12a51b9ce8241427cea 824 Pfam PF13426 PAS domain 451 556 1.0E-15 T 10-11-2016 IPR000014 PAS domain A4G23_RS12225 cba8bc89c316d12a51b9ce8241427cea 824 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 619 814 1.6E-41 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS12225 cba8bc89c316d12a51b9ce8241427cea 824 SMART SM00091 316 382 3.2E-8 T 10-11-2016 IPR000014 PAS domain A4G23_RS12225 cba8bc89c316d12a51b9ce8241427cea 824 SMART SM00091 441 507 6.2E-11 T 10-11-2016 IPR000014 PAS domain A4G23_RS12225 cba8bc89c316d12a51b9ce8241427cea 824 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 438 563 4.9E-24 T 10-11-2016 IPR000014 PAS domain A4G23_RS12225 cba8bc89c316d12a51b9ce8241427cea 824 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 314 435 2.5E-17 T 10-11-2016 IPR000014 PAS domain A4G23_RS12225 cba8bc89c316d12a51b9ce8241427cea 824 Gene3D G3DSA:3.30.450.20 428 555 1.0E-26 T 10-11-2016 A4G23_RS07450 571f62366286ba9f90b02714307ea4d4 419 SUPERFAMILY SSF55874 291 414 2.76E-10 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS07450 571f62366286ba9f90b02714307ea4d4 419 Pfam PF07730 Histidine kinase 211 276 7.7E-20 T 10-11-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4G23_RS12855 188ed25c7a92e6d4ba082823037fd3ee 68 SUPERFAMILY SSF46955 11 59 2.61E-11 T 10-11-2016 IPR009061 Putative DNA-binding domain A4G23_RS12855 188ed25c7a92e6d4ba082823037fd3ee 68 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 11 58 1.2E-8 T 10-11-2016 IPR010093 SinI-like, DNA-binding domain GO:0003677 A4G23_RS12855 188ed25c7a92e6d4ba082823037fd3ee 68 Pfam PF12728 Helix-turn-helix domain 11 59 1.3E-11 T 10-11-2016 A4G23_RS12855 188ed25c7a92e6d4ba082823037fd3ee 68 Gene3D G3DSA:1.10.1660.10 11 57 5.4E-7 T 10-11-2016 A4G23_RS04930 e609b6f735b4196087734aec4d34b7a9 538 Pfam PF13556 PucR C-terminal helix-turn-helix domain 476 534 1.9E-20 T 10-11-2016 IPR025736 PucR C-terminal helix-turn-helix domain A4G23_RS04930 e609b6f735b4196087734aec4d34b7a9 538 Pfam PF07905 Purine catabolism regulatory protein-like family 12 132 1.2E-37 T 10-11-2016 IPR012914 Purine catabolism PurC-like domain A4G23_RS04930 e609b6f735b4196087734aec4d34b7a9 538 Gene3D G3DSA:1.10.10.60 480 512 4.4E-6 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS15340 2bc081c6282072031fee5f7290da5ccc 386 Gene3D G3DSA:1.10.645.10 19 376 4.2E-61 T 10-11-2016 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS15340 2bc081c6282072031fee5f7290da5ccc 386 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 137 310 1.2E-46 T 10-11-2016 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS15340 2bc081c6282072031fee5f7290da5ccc 386 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 312 386 7.3E-20 T 10-11-2016 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS15340 2bc081c6282072031fee5f7290da5ccc 386 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 17 386 40.663 T 10-11-2016 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS15340 2bc081c6282072031fee5f7290da5ccc 386 SUPERFAMILY SSF56762 32 385 1.57E-102 T 10-11-2016 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS15340 2bc081c6282072031fee5f7290da5ccc 386 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 59 70 - T 10-11-2016 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS12970 bbee8d269403c15edb810743daacf274 813 Gene3D G3DSA:3.40.50.300 15 167 7.2E-60 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS12970 bbee8d269403c15edb810743daacf274 813 Gene3D G3DSA:1.20.272.10 246 364 2.1E-15 T 10-11-2016 A4G23_RS12970 bbee8d269403c15edb810743daacf274 813 SUPERFAMILY SSF48019 247 365 4.59E-22 T 10-11-2016 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 A4G23_RS12970 bbee8d269403c15edb810743daacf274 813 Pfam PF13177 DNA polymerase III, delta subunit 20 178 2.0E-37 T 10-11-2016 A4G23_RS12970 bbee8d269403c15edb810743daacf274 813 SMART SM00382 37 181 4.0E-10 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS12970 bbee8d269403c15edb810743daacf274 813 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 236 364 3.3E-14 T 10-11-2016 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 A4G23_RS12970 bbee8d269403c15edb810743daacf274 813 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 5 363 5.3E-116 T 10-11-2016 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 A4G23_RS12970 bbee8d269403c15edb810743daacf274 813 Gene3D G3DSA:1.10.8.60 168 245 7.3E-20 T 10-11-2016 A4G23_RS12970 bbee8d269403c15edb810743daacf274 813 SUPERFAMILY SSF52540 32 222 4.2E-51 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS16495 a0e41c2799cf2c613b8f5763b914b45c 123 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 2 123 2.9E-68 T 10-11-2016 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS16495 a0e41c2799cf2c613b8f5763b914b45c 123 PRINTS PR01034 Ribosomal protein S12 signature 58 77 8.4E-59 T 10-11-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS16495 a0e41c2799cf2c613b8f5763b914b45c 123 PRINTS PR01034 Ribosomal protein S12 signature 110 122 8.4E-59 T 10-11-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS16495 a0e41c2799cf2c613b8f5763b914b45c 123 PRINTS PR01034 Ribosomal protein S12 signature 94 110 8.4E-59 T 10-11-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS16495 a0e41c2799cf2c613b8f5763b914b45c 123 PRINTS PR01034 Ribosomal protein S12 signature 42 57 8.4E-59 T 10-11-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS16495 a0e41c2799cf2c613b8f5763b914b45c 123 PRINTS PR01034 Ribosomal protein S12 signature 77 94 8.4E-59 T 10-11-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS16495 a0e41c2799cf2c613b8f5763b914b45c 123 PRINTS PR01034 Ribosomal protein S12 signature 27 42 8.4E-59 T 10-11-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS16495 a0e41c2799cf2c613b8f5763b914b45c 123 PIRSF PIRSF002133 1 123 8.4E-55 T 10-11-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS16495 a0e41c2799cf2c613b8f5763b914b45c 123 Gene3D G3DSA:2.40.50.140 2 123 3.3E-65 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS16495 a0e41c2799cf2c613b8f5763b914b45c 123 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 10-11-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS16495 a0e41c2799cf2c613b8f5763b914b45c 123 Pfam PF00164 Ribosomal protein S12/S23 3 123 1.5E-44 T 10-11-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS16495 a0e41c2799cf2c613b8f5763b914b45c 123 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 39.977 T 10-11-2016 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS16495 a0e41c2799cf2c613b8f5763b914b45c 123 SUPERFAMILY SSF50249 2 123 6.77E-53 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS03760 f086e1f18234805ba59e61964d731ecb 403 Gene3D G3DSA:3.40.50.2000 164 355 5.9E-28 T 10-11-2016 A4G23_RS03760 f086e1f18234805ba59e61964d731ecb 403 Pfam PF13439 Glycosyltransferase Family 4 14 173 5.0E-34 T 10-11-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A4G23_RS03760 f086e1f18234805ba59e61964d731ecb 403 SUPERFAMILY SSF53756 2 379 4.08E-82 T 10-11-2016 A4G23_RS03760 f086e1f18234805ba59e61964d731ecb 403 Pfam PF13692 Glycosyl transferases group 1 204 344 6.6E-30 T 10-11-2016 A4G23_RS21160 86a41264d9af7b03f435a3c78d7bce36 439 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 11 262 3.6E-81 T 10-11-2016 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0016020 A4G23_RS21160 86a41264d9af7b03f435a3c78d7bce36 439 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 294 405 6.6E-24 T 10-11-2016 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0016020 A4G23_RS17170 ced2412021dc00a26bbe7050280cb830 300 SUPERFAMILY SSF88946 39 119 7.46E-8 T 10-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS17170 ced2412021dc00a26bbe7050280cb830 300 Gene3D G3DSA:1.10.10.10 127 182 6.0E-6 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS17170 ced2412021dc00a26bbe7050280cb830 300 SUPERFAMILY SSF88659 127 182 2.88E-6 T 10-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS17170 ced2412021dc00a26bbe7050280cb830 300 Pfam PF08281 Sigma-70, region 4 127 178 4.9E-6 T 10-11-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS17170 ced2412021dc00a26bbe7050280cb830 300 Gene3D G3DSA:1.10.1740.10 40 112 3.8E-7 T 10-11-2016 A4G23_RS07935 3b2d43128982354bfcfca649e7fc69ea 245 Pfam PF00753 Metallo-beta-lactamase superfamily 27 222 1.8E-13 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS07935 3b2d43128982354bfcfca649e7fc69ea 245 Gene3D G3DSA:3.60.15.10 6 241 4.5E-44 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS07935 3b2d43128982354bfcfca649e7fc69ea 245 SUPERFAMILY SSF56281 5 241 2.52E-37 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS07935 3b2d43128982354bfcfca649e7fc69ea 245 SMART SM00849 26 222 3.5E-17 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS10625 323cddc05008e0253504cd191dce0c91 632 SUPERFAMILY SSF50998 248 528 5.23E-11 T 10-11-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily A4G23_RS10625 323cddc05008e0253504cd191dce0c91 632 Pfam PF13360 PQQ-like domain 310 526 7.6E-10 T 10-11-2016 IPR002372 Pyrrolo-quinoline quinone repeat A4G23_RS14995 fe9d7ec5973f9480eccd74bf543f674b 503 SUPERFAMILY SSF53474 419 473 6.28E-22 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS14995 fe9d7ec5973f9480eccd74bf543f674b 503 SUPERFAMILY SSF53474 178 347 6.28E-22 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS14995 fe9d7ec5973f9480eccd74bf543f674b 503 SUPERFAMILY SSF53474 71 138 6.28E-22 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS14995 fe9d7ec5973f9480eccd74bf543f674b 503 Gene3D G3DSA:3.40.50.1820 368 488 2.2E-53 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS14995 fe9d7ec5973f9480eccd74bf543f674b 503 Gene3D G3DSA:3.40.50.1820 188 312 2.2E-53 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS14995 fe9d7ec5973f9480eccd74bf543f674b 503 Gene3D G3DSA:3.40.50.1820 57 143 2.2E-53 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS14995 fe9d7ec5973f9480eccd74bf543f674b 503 Pfam PF00561 alpha/beta hydrolase fold 93 474 9.3E-27 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS17520 91d9e21aedab0c919c0f53c299c235d8 526 Gene3D G3DSA:3.20.20.240 5 520 9.2E-228 T 10-11-2016 IPR014348 Cobalamin (vitamin B12)-dependent enzyme, catalytic subdomain GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A4G23_RS17520 91d9e21aedab0c919c0f53c299c235d8 526 Pfam PF01642 Methylmalonyl-CoA mutase 6 518 4.6E-224 T 10-11-2016 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A4G23_RS17520 91d9e21aedab0c919c0f53c299c235d8 526 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 5 522 5.1E-238 T 10-11-2016 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A4G23_RS17520 91d9e21aedab0c919c0f53c299c235d8 526 SUPERFAMILY SSF51703 3 520 6.67E-211 T 10-11-2016 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A4G23_RS05635 89e7cf51bc738ad09c11c1cfd9686069 261 TIGRFAM TIGR01198 pgl: 6-phosphogluconolactonase 8 249 6.0E-77 T 10-11-2016 IPR005900 6-phosphogluconolactonase, DevB-type GO:0005975|GO:0006098|GO:0017057 KEGG: 00030+3.1.1.31 A4G23_RS05635 89e7cf51bc738ad09c11c1cfd9686069 261 SUPERFAMILY SSF100950 5 252 1.88E-63 T 10-11-2016 A4G23_RS05635 89e7cf51bc738ad09c11c1cfd9686069 261 Gene3D G3DSA:3.40.50.1360 4 250 3.5E-75 T 10-11-2016 A4G23_RS05635 89e7cf51bc738ad09c11c1cfd9686069 261 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 11 240 1.0E-75 T 10-11-2016 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 A4G23_RS06035 878ea4996beff2657c038e73e541b978 128 Gene3D G3DSA:3.10.180.10 2 127 4.2E-20 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS06035 878ea4996beff2657c038e73e541b978 128 SUPERFAMILY SSF54593 3 126 2.55E-23 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS06035 878ea4996beff2657c038e73e541b978 128 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 122 4.2E-11 T 10-11-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4G23_RS19295 89e9cee26761b0072439b4895232a796 204 SUPERFAMILY SSF52540 27 201 2.13E-20 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS19295 89e9cee26761b0072439b4895232a796 204 Pfam PF03029 Conserved hypothetical ATP binding protein 32 199 2.8E-25 T 10-11-2016 IPR004130 GPN-loop GTPase A4G23_RS19295 89e9cee26761b0072439b4895232a796 204 Gene3D G3DSA:3.40.50.300 27 201 4.0E-14 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS00465 cb6382823e8fbb8c2f480a575b0c8540 271 Pfam PF06314 Acetoacetate decarboxylase (ADC) 12 105 3.2E-12 T 10-11-2016 IPR010451 Acetoacetate decarboxylase GO:0016829 KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 A4G23_RS00465 cb6382823e8fbb8c2f480a575b0c8540 271 SUPERFAMILY SSF160104 4 111 5.75E-17 T 10-11-2016 A4G23_RS00465 cb6382823e8fbb8c2f480a575b0c8540 271 Gene3D G3DSA:2.40.400.10 4 105 6.2E-12 T 10-11-2016 IPR023375 Acetoacetate decarboxylase beta barrel domain KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 A4G23_RS05800 dfbefdd41a13b569b8e8283ec2a85504 256 Pfam PF03777 Small secreted domain (DUF320) 116 168 8.1E-20 T 10-11-2016 IPR005528 Domain of unknown function DUF320, Streptomyces species A4G23_RS05800 dfbefdd41a13b569b8e8283ec2a85504 256 Pfam PF03777 Small secreted domain (DUF320) 24 79 1.7E-28 T 10-11-2016 IPR005528 Domain of unknown function DUF320, Streptomyces species A4G23_RS26935 c01a87a3281ef097392b2d75bd580f33 148 Pfam PF03779 SPW repeat 82 129 1.4E-13 T 10-11-2016 IPR005530 SPW repeat A4G23_RS26935 c01a87a3281ef097392b2d75bd580f33 148 Pfam PF03779 SPW repeat 30 66 7.1E-10 T 10-11-2016 IPR005530 SPW repeat A4G23_RS17095 b10340ff4d98eec8634d45dca9f840f3 367 SUPERFAMILY SSF54001 251 362 3.48E-41 T 10-11-2016 A4G23_RS17095 b10340ff4d98eec8634d45dca9f840f3 367 Gene3D G3DSA:3.90.1720.10 251 358 1.0E-43 T 10-11-2016 IPR000064 Endopeptidase, NLPC/P60 domain A4G23_RS17095 b10340ff4d98eec8634d45dca9f840f3 367 Pfam PF00877 NlpC/P60 family 267 362 2.7E-26 T 10-11-2016 IPR000064 Endopeptidase, NLPC/P60 domain A4G23_RS06460 22f61da5cdaa010ae5d69419a61149f5 420 SUPERFAMILY SSF52540 1 54 1.19E-24 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS06460 22f61da5cdaa010ae5d69419a61149f5 420 SUPERFAMILY SSF52540 87 297 1.19E-24 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS06460 22f61da5cdaa010ae5d69419a61149f5 420 Gene3D G3DSA:3.40.50.300 88 188 1.0E-26 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS06460 22f61da5cdaa010ae5d69419a61149f5 420 Gene3D G3DSA:3.40.50.300 3 51 1.0E-26 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS06460 22f61da5cdaa010ae5d69419a61149f5 420 Gene3D G3DSA:3.40.50.300 221 312 1.0E-26 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS06460 22f61da5cdaa010ae5d69419a61149f5 420 Pfam PF02374 Anion-transporting ATPase 1 43 2.0E-10 T 10-11-2016 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 A4G23_RS06460 22f61da5cdaa010ae5d69419a61149f5 420 Pfam PF02374 Anion-transporting ATPase 89 298 1.4E-9 T 10-11-2016 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 A4G23_RS18570 e28f1b70bc650bd42ab811c9b262b09c 584 SUPERFAMILY SSF50156 516 581 1.03E-18 T 10-11-2016 IPR001478 PDZ domain GO:0005515 A4G23_RS18570 e28f1b70bc650bd42ab811c9b262b09c 584 Pfam PF13365 Trypsin-like peptidase domain 295 441 1.4E-33 T 10-11-2016 A4G23_RS18570 e28f1b70bc650bd42ab811c9b262b09c 584 SUPERFAMILY SSF50494 258 494 1.43E-55 T 10-11-2016 IPR009003 Peptidase S1, PA clan A4G23_RS18570 e28f1b70bc650bd42ab811c9b262b09c 584 Gene3D G3DSA:2.30.42.10 492 580 1.5E-20 T 10-11-2016 IPR001478 PDZ domain GO:0005515 A4G23_RS18570 e28f1b70bc650bd42ab811c9b262b09c 584 Gene3D G3DSA:2.40.10.10 369 491 1.9E-42 T 10-11-2016 A4G23_RS18570 e28f1b70bc650bd42ab811c9b262b09c 584 PRINTS PR00834 HtrA/DegQ protease family signature 328 348 1.5E-42 T 10-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4G23_RS18570 e28f1b70bc650bd42ab811c9b262b09c 584 PRINTS PR00834 HtrA/DegQ protease family signature 527 539 1.5E-42 T 10-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4G23_RS18570 e28f1b70bc650bd42ab811c9b262b09c 584 PRINTS PR00834 HtrA/DegQ protease family signature 412 429 1.5E-42 T 10-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4G23_RS18570 e28f1b70bc650bd42ab811c9b262b09c 584 PRINTS PR00834 HtrA/DegQ protease family signature 434 451 1.5E-42 T 10-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4G23_RS18570 e28f1b70bc650bd42ab811c9b262b09c 584 PRINTS PR00834 HtrA/DegQ protease family signature 369 393 1.5E-42 T 10-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4G23_RS18570 e28f1b70bc650bd42ab811c9b262b09c 584 PRINTS PR00834 HtrA/DegQ protease family signature 304 316 1.5E-42 T 10-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4G23_RS18570 e28f1b70bc650bd42ab811c9b262b09c 584 Gene3D G3DSA:2.40.10.10 291 368 1.1E-26 T 10-11-2016 A4G23_RS18570 e28f1b70bc650bd42ab811c9b262b09c 584 Pfam PF13180 PDZ domain 489 572 3.1E-18 T 10-11-2016 IPR001478 PDZ domain GO:0005515 A4G23_RS18570 e28f1b70bc650bd42ab811c9b262b09c 584 SMART SM00228 489 569 2.4E-10 T 10-11-2016 IPR001478 PDZ domain GO:0005515 A4G23_RS08550 5da19c0776af0e87e15b477dfd57ade5 464 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 424 458 7.4E-5 T 10-11-2016 IPR019931 LPXTG cell wall anchor domain A4G23_RS08550 5da19c0776af0e87e15b477dfd57ade5 464 TIGRFAM TIGR03934 TQXA_dom: TQXA domain 104 152 1.9E-16 T 10-11-2016 IPR023849 Uncharacterised domain CHP03934, TQXA A4G23_RS06115 7f50692cb715941f540a461d93aac4fb 1179 Gene3D G3DSA:2.40.50.140 1016 1096 2.6E-4 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS06115 7f50692cb715941f540a461d93aac4fb 1179 Pfam PF01336 OB-fold nucleic acid binding domain 1020 1096 9.2E-7 T 10-11-2016 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A4G23_RS06115 7f50692cb715941f540a461d93aac4fb 1179 Pfam PF14579 Helix-hairpin-helix motif 829 918 3.1E-25 T 10-11-2016 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4G23_RS06115 7f50692cb715941f540a461d93aac4fb 1179 Pfam PF02811 PHP domain 8 194 2.0E-42 T 10-11-2016 IPR004013 PHP domain GO:0003824 A4G23_RS06115 7f50692cb715941f540a461d93aac4fb 1179 Gene3D G3DSA:3.20.20.140 7 268 3.4E-38 T 10-11-2016 A4G23_RS06115 7f50692cb715941f540a461d93aac4fb 1179 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 6 1057 0.0 T 10-11-2016 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4G23_RS06115 7f50692cb715941f540a461d93aac4fb 1179 SUPERFAMILY SSF89550 7 92 4.45E-29 T 10-11-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A4G23_RS06115 7f50692cb715941f540a461d93aac4fb 1179 SUPERFAMILY SSF89550 120 269 4.45E-29 T 10-11-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A4G23_RS06115 7f50692cb715941f540a461d93aac4fb 1179 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 316 756 1.4E-163 T 10-11-2016 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4G23_RS06115 7f50692cb715941f540a461d93aac4fb 1179 SMART SM00481 7 74 8.4E-29 T 10-11-2016 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 A4G23_RS25235 d6b0f5cfa6319332affbeee39fdd17c6 312 SUPERFAMILY SSF53850 94 278 3.41E-20 T 10-11-2016 A4G23_RS25235 d6b0f5cfa6319332affbeee39fdd17c6 312 Gene3D G3DSA:3.40.190.10 104 183 4.8E-11 T 10-11-2016 A4G23_RS25235 d6b0f5cfa6319332affbeee39fdd17c6 312 Gene3D G3DSA:1.10.10.10 1 84 2.2E-22 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS25235 d6b0f5cfa6319332affbeee39fdd17c6 312 Gene3D G3DSA:3.40.190.10 184 266 6.4E-17 T 10-11-2016 A4G23_RS25235 d6b0f5cfa6319332affbeee39fdd17c6 312 SUPERFAMILY SSF46785 1 112 3.86E-19 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS25235 d6b0f5cfa6319332affbeee39fdd17c6 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 37 48 5.8E-8 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS25235 d6b0f5cfa6319332affbeee39fdd17c6 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 16 27 5.8E-8 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS25235 d6b0f5cfa6319332affbeee39fdd17c6 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 27 37 5.8E-8 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS25235 d6b0f5cfa6319332affbeee39fdd17c6 312 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 1 60 2.9E-18 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS25235 d6b0f5cfa6319332affbeee39fdd17c6 312 Pfam PF03466 LysR substrate binding domain 94 291 5.3E-23 T 10-11-2016 IPR005119 LysR, substrate-binding A4G23_RS25650 ddd62325ea6a6444a67b6dd4fcabb804 862 Pfam PF03235 Protein of unknown function DUF262 9 230 2.2E-33 T 10-11-2016 IPR004919 Domain of unknown function DUF262 A4G23_RS25650 ddd62325ea6a6444a67b6dd4fcabb804 862 SUPERFAMILY SSF46767 581 639 2.09E-8 T 10-11-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A4G23_RS25650 ddd62325ea6a6444a67b6dd4fcabb804 862 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 585 641 4.2E-8 T 10-11-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A4G23_RS25650 ddd62325ea6a6444a67b6dd4fcabb804 862 Gene3D G3DSA:1.10.10.10 585 665 3.8E-8 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS25650 ddd62325ea6a6444a67b6dd4fcabb804 862 Pfam PF07510 Protein of unknown function (DUF1524) 416 558 5.2E-28 T 10-11-2016 IPR011089 Domain of unknown function DUF1524 A4G23_RS25285 269ede1ed1419d18dc293b936fadfea8 279 Pfam PF02585 GlcNAc-PI de-N-acetylase 26 167 2.7E-14 T 10-11-2016 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 A4G23_RS25285 269ede1ed1419d18dc293b936fadfea8 279 Gene3D G3DSA:3.40.50.10320 24 233 1.2E-23 T 10-11-2016 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 A4G23_RS25285 269ede1ed1419d18dc293b936fadfea8 279 SUPERFAMILY SSF102588 24 243 5.23E-32 T 10-11-2016 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 A4G23_RS13370 c796a2f1986b6bdd6e4b85ada3d9e470 255 Pfam PF05949 Bacterial protein of unknown function (DUF881) 99 252 7.3E-42 T 10-11-2016 IPR010273 Protein of unknown function DUF881 A4G23_RS19860 169737f0ad0cb3bfd3e69596e6cc1515 283 Gene3D G3DSA:3.40.710.10 22 224 2.7E-40 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS19860 169737f0ad0cb3bfd3e69596e6cc1515 283 SUPERFAMILY SSF56601 25 255 1.94E-43 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS19860 169737f0ad0cb3bfd3e69596e6cc1515 283 Pfam PF00144 Beta-lactamase 21 237 9.3E-38 T 10-11-2016 IPR001466 Beta-lactamase-related A4G23_RS10355 7979ffb0944661abd589397ac093201c 66 SUPERFAMILY SSF143011 2 62 1.83E-16 T 10-11-2016 A4G23_RS10355 7979ffb0944661abd589397ac093201c 66 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 3 61 4.8E-10 T 10-11-2016 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family A4G23_RS04870 ad1281d1e6a2fbbeb8e22737ec144688 347 Pfam PF03747 ADP-ribosylglycohydrolase 21 326 6.3E-58 T 10-11-2016 IPR005502 ADP-ribosylation/Crystallin J1 A4G23_RS04870 ad1281d1e6a2fbbeb8e22737ec144688 347 SUPERFAMILY SSF101478 19 234 2.75E-56 T 10-11-2016 IPR005502 ADP-ribosylation/Crystallin J1 A4G23_RS04870 ad1281d1e6a2fbbeb8e22737ec144688 347 SUPERFAMILY SSF101478 267 341 2.75E-56 T 10-11-2016 IPR005502 ADP-ribosylation/Crystallin J1 A4G23_RS01065 44408f83853e12fdab9cee1745ed2955 321 Gene3D G3DSA:3.40.50.2000 195 297 2.1E-6 T 10-11-2016 A4G23_RS01065 44408f83853e12fdab9cee1745ed2955 321 Pfam PF00534 Glycosyl transferases group 1 192 296 6.1E-9 T 10-11-2016 IPR001296 Glycosyl transferase, family 1 A4G23_RS01065 44408f83853e12fdab9cee1745ed2955 321 SUPERFAMILY SSF53756 192 319 2.2E-18 T 10-11-2016 A4G23_RS11535 11323c3dd8278d38dc6a0e73775b2baa 257 Pfam PF13847 Methyltransferase domain 42 158 7.4E-22 T 10-11-2016 IPR025714 Methyltransferase domain A4G23_RS11535 11323c3dd8278d38dc6a0e73775b2baa 257 SUPERFAMILY SSF53335 20 252 1.45E-38 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS11535 11323c3dd8278d38dc6a0e73775b2baa 257 Gene3D G3DSA:3.40.50.150 26 197 1.5E-37 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS08675 a0dbe24b040291128b1de850f3033879 252 SMART SM00866 98 242 3.0E-16 T 10-11-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A4G23_RS08675 a0dbe24b040291128b1de850f3033879 252 Gene3D G3DSA:3.40.1410.10 70 245 1.1E-55 T 10-11-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain A4G23_RS08675 a0dbe24b040291128b1de850f3033879 252 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 69 4.9E-15 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS08675 a0dbe24b040291128b1de850f3033879 252 SMART SM00345 10 69 1.5E-14 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS08675 a0dbe24b040291128b1de850f3033879 252 SUPERFAMILY SSF64288 57 248 1.26E-31 T 10-11-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain A4G23_RS08675 a0dbe24b040291128b1de850f3033879 252 SUPERFAMILY SSF46785 3 80 1.09E-17 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS08675 a0dbe24b040291128b1de850f3033879 252 Gene3D G3DSA:1.10.10.10 3 69 2.8E-21 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS08675 a0dbe24b040291128b1de850f3033879 252 Pfam PF07702 UTRA domain 112 240 1.7E-19 T 10-11-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A4G23_RS13150 de3dcab2e09186ed613c7c5aa50b6ad2 221 Gene3D G3DSA:1.10.10.10 5 77 1.3E-21 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS13150 de3dcab2e09186ed613c7c5aa50b6ad2 221 SUPERFAMILY SSF46785 10 81 2.18E-17 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS13150 de3dcab2e09186ed613c7c5aa50b6ad2 221 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 5.8E-8 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS13150 de3dcab2e09186ed613c7c5aa50b6ad2 221 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 5.8E-8 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS13150 de3dcab2e09186ed613c7c5aa50b6ad2 221 SMART SM00895 87 211 4.8E-16 T 10-11-2016 IPR011711 GntR, C-terminal A4G23_RS13150 de3dcab2e09186ed613c7c5aa50b6ad2 221 Pfam PF07729 FCD domain 87 209 3.2E-22 T 10-11-2016 IPR011711 GntR, C-terminal A4G23_RS13150 de3dcab2e09186ed613c7c5aa50b6ad2 221 Gene3D G3DSA:1.20.120.530 81 218 4.4E-29 T 10-11-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal A4G23_RS13150 de3dcab2e09186ed613c7c5aa50b6ad2 221 SUPERFAMILY SSF48008 83 217 1.44E-27 T 10-11-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal A4G23_RS13150 de3dcab2e09186ed613c7c5aa50b6ad2 221 SMART SM00345 19 77 2.9E-10 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS13150 de3dcab2e09186ed613c7c5aa50b6ad2 221 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 77 2.2E-16 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS19515 c9872b58874278659d53e3558c0ffc44 293 SUPERFAMILY SSF53335 21 287 1.41E-47 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS19515 c9872b58874278659d53e3558c0ffc44 293 Gene3D G3DSA:1.10.8.10 20 95 8.4E-18 T 10-11-2016 A4G23_RS19515 c9872b58874278659d53e3558c0ffc44 293 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 193 199 - T 10-11-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A4G23_RS19515 c9872b58874278659d53e3558c0ffc44 293 Gene3D G3DSA:3.40.50.150 97 290 1.6E-56 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS19515 c9872b58874278659d53e3558c0ffc44 293 Pfam PF05175 Methyltransferase small domain 126 199 1.8E-12 T 10-11-2016 IPR007848 Methyltransferase small domain GO:0008168 A4G23_RS19515 c9872b58874278659d53e3558c0ffc44 293 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 16 290 41.857 T 10-11-2016 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 A4G23_RS19515 c9872b58874278659d53e3558c0ffc44 293 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 65 291 5.5E-48 T 10-11-2016 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 A4G23_RS19515 c9872b58874278659d53e3558c0ffc44 293 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 38 286 2.5E-71 T 10-11-2016 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 A4G23_RS08870 cdfd4e09d8a9d8304ceae2d3031d1e4a 512 SUPERFAMILY SSF51658 44 145 6.08E-5 T 10-11-2016 IPR013022 Xylose isomerase-like, TIM barrel domain A4G23_RS08870 cdfd4e09d8a9d8304ceae2d3031d1e4a 512 Pfam PF07905 Purine catabolism regulatory protein-like family 2 106 6.3E-23 T 10-11-2016 IPR012914 Purine catabolism PurC-like domain A4G23_RS08870 cdfd4e09d8a9d8304ceae2d3031d1e4a 512 Pfam PF13556 PucR C-terminal helix-turn-helix domain 453 510 2.1E-19 T 10-11-2016 IPR025736 PucR C-terminal helix-turn-helix domain A4G23_RS22285 0b9867e1d709c5edccf75cc8879a7ce8 431 Gene3D G3DSA:2.120.10.20 16 428 8.7E-114 T 10-11-2016 IPR003431 Beta propeller phytase GO:0016158 KEGG: 00562+3.1.3.8|MetaCyc: PWY-4702 A4G23_RS22285 0b9867e1d709c5edccf75cc8879a7ce8 431 Pfam PF02333 Phytase 282 428 1.8E-35 T 10-11-2016 IPR003431 Beta propeller phytase GO:0016158 KEGG: 00562+3.1.3.8|MetaCyc: PWY-4702 A4G23_RS22285 0b9867e1d709c5edccf75cc8879a7ce8 431 Pfam PF02333 Phytase 21 147 2.2E-19 T 10-11-2016 IPR003431 Beta propeller phytase GO:0016158 KEGG: 00562+3.1.3.8|MetaCyc: PWY-4702 A4G23_RS22285 0b9867e1d709c5edccf75cc8879a7ce8 431 SUPERFAMILY SSF50956 17 281 1.7E-60 T 10-11-2016 A4G23_RS22285 0b9867e1d709c5edccf75cc8879a7ce8 431 SUPERFAMILY SSF50956 308 428 1.7E-60 T 10-11-2016 A4G23_RS14125 92547bcab0c7f4c9d7500385b0318de5 136 SUPERFAMILY SSF46955 9 130 1.03E-25 T 10-11-2016 IPR009061 Putative DNA-binding domain A4G23_RS14125 92547bcab0c7f4c9d7500385b0318de5 136 SMART SM00422 9 78 7.0E-22 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS14125 92547bcab0c7f4c9d7500385b0318de5 136 Pfam PF13411 MerR HTH family regulatory protein 9 76 3.2E-16 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS14125 92547bcab0c7f4c9d7500385b0318de5 136 Gene3D G3DSA:1.10.1660.10 9 131 1.1E-28 T 10-11-2016 A4G23_RS11320 3d867926a16e36f0a5a83cd26fb7cc11 559 Gene3D G3DSA:3.50.50.60 73 148 3.6E-18 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS11320 3d867926a16e36f0a5a83cd26fb7cc11 559 Gene3D G3DSA:3.50.50.60 270 312 3.6E-18 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS11320 3d867926a16e36f0a5a83cd26fb7cc11 559 Gene3D G3DSA:3.50.50.60 1 41 3.6E-18 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS11320 3d867926a16e36f0a5a83cd26fb7cc11 559 Pfam PF04820 Tryptophan halogenase 70 367 6.7E-19 T 10-11-2016 IPR006905 Tryptophan halogenase A4G23_RS11320 3d867926a16e36f0a5a83cd26fb7cc11 559 SUPERFAMILY SSF51905 2 146 9.32E-26 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS11320 3d867926a16e36f0a5a83cd26fb7cc11 559 SUPERFAMILY SSF51905 262 361 9.32E-26 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS08195 97e6c5df8e9ab7862e851414467663b4 542 SUPERFAMILY SSF53448 4 214 1.69E-43 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS08195 97e6c5df8e9ab7862e851414467663b4 542 Gene3D G3DSA:3.90.550.10 3 198 4.4E-42 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS08195 97e6c5df8e9ab7862e851414467663b4 542 Pfam PF00535 Glycosyl transferase family 2 7 135 7.9E-27 T 10-11-2016 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A4G23_RS19550 9160509a2d1bd942d6f25886ea2d647a 77 Pfam PF00137 ATP synthase subunit C 19 75 1.7E-12 T 10-11-2016 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 A4G23_RS19550 9160509a2d1bd942d6f25886ea2d647a 77 SUPERFAMILY SSF81333 17 76 1.7E-16 T 10-11-2016 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 A4G23_RS19550 9160509a2d1bd942d6f25886ea2d647a 77 ProSitePatterns PS00605 ATP synthase c subunit signature. 42 63 - T 10-11-2016 IPR020537 ATPase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210 A4G23_RS19550 9160509a2d1bd942d6f25886ea2d647a 77 Gene3D G3DSA:1.20.20.10 16 76 1.9E-22 T 10-11-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 A4G23_RS19550 9160509a2d1bd942d6f25886ea2d647a 77 PRINTS PR00124 ATP synthase C subunit signature 52 77 4.3E-18 T 10-11-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 A4G23_RS19550 9160509a2d1bd942d6f25886ea2d647a 77 PRINTS PR00124 ATP synthase C subunit signature 35 50 4.3E-18 T 10-11-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 A4G23_RS19550 9160509a2d1bd942d6f25886ea2d647a 77 PRINTS PR00124 ATP synthase C subunit signature 14 33 4.3E-18 T 10-11-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 A4G23_RS19550 9160509a2d1bd942d6f25886ea2d647a 77 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 22 75 5.3E-15 T 10-11-2016 IPR005953 ATPase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 A4G23_RS19550 9160509a2d1bd942d6f25886ea2d647a 77 Hamap MF_01396 ATP synthase subunit c [atpH]. 11 77 12.618 T 10-11-2016 A4G23_RS04280 44f8c69fd70a7b7a4896c323f3ea2395 427 Pfam PF07690 Major Facilitator Superfamily 43 335 8.5E-12 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS04280 44f8c69fd70a7b7a4896c323f3ea2395 427 Gene3D G3DSA:1.20.1250.20 211 390 1.2E-7 T 10-11-2016 A4G23_RS04280 44f8c69fd70a7b7a4896c323f3ea2395 427 Gene3D G3DSA:1.20.1250.20 19 202 6.8E-10 T 10-11-2016 A4G23_RS04280 44f8c69fd70a7b7a4896c323f3ea2395 427 SUPERFAMILY SSF103473 18 390 9.02E-26 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS23020 180ac77b3d909b695b8ceec74f8487e8 142 TIGRFAM TIGR03562 osmo_induc_OsmC: peroxiredoxin, OsmC subfamily 5 138 2.0E-52 T 10-11-2016 IPR019904 Peroxiredoxin OsmC GO:0004601|GO:0006979 KEGG: 00480+1.11.1.15 A4G23_RS23020 180ac77b3d909b695b8ceec74f8487e8 142 SUPERFAMILY SSF82784 4 132 3.4E-32 T 10-11-2016 IPR003718 OsmC/Ohr family A4G23_RS23020 180ac77b3d909b695b8ceec74f8487e8 142 Gene3D G3DSA:3.30.300.20 4 140 6.6E-45 T 10-11-2016 IPR015946 K homology domain-like, alpha/beta A4G23_RS23020 180ac77b3d909b695b8ceec74f8487e8 142 Pfam PF02566 OsmC-like protein 44 136 2.7E-19 T 10-11-2016 IPR003718 OsmC/Ohr family A4G23_RS09105 ed77a9cb7bcd100eebdcd474feb0faf8 193 Pfam PF14435 SUKH-4 immunity protein 8 184 2.2E-21 T 10-11-2016 IPR025851 SUKH-4 immunity protein A4G23_RS26255 d4dc04fcdccdcf0db4f9d88b1c7cdd62 493 Pfam PF00916 Sulfate permease family 13 380 3.4E-57 T 10-11-2016 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 A4G23_RS13775 d6ef2e34019fe68792e3e649233bed7a 467 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 328 6.7E-69 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS13775 d6ef2e34019fe68792e3e649233bed7a 467 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 348 456 8.3E-35 T 10-11-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A4G23_RS13775 d6ef2e34019fe68792e3e649233bed7a 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 293 315 4.5E-37 T 10-11-2016 A4G23_RS13775 d6ef2e34019fe68792e3e649233bed7a 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 138 156 4.5E-37 T 10-11-2016 A4G23_RS13775 d6ef2e34019fe68792e3e649233bed7a 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 264 280 4.5E-37 T 10-11-2016 A4G23_RS13775 d6ef2e34019fe68792e3e649233bed7a 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 4.5E-37 T 10-11-2016 A4G23_RS13775 d6ef2e34019fe68792e3e649233bed7a 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 176 194 4.5E-37 T 10-11-2016 A4G23_RS13775 d6ef2e34019fe68792e3e649233bed7a 467 Gene3D G3DSA:3.30.390.30 335 465 9.1E-45 T 10-11-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A4G23_RS13775 d6ef2e34019fe68792e3e649233bed7a 467 SUPERFAMILY SSF55424 344 466 7.39E-39 T 10-11-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 A4G23_RS13775 d6ef2e34019fe68792e3e649233bed7a 467 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 10-11-2016 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 A4G23_RS13775 d6ef2e34019fe68792e3e649233bed7a 467 Gene3D G3DSA:3.50.50.60 145 334 2.1E-54 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS13775 d6ef2e34019fe68792e3e649233bed7a 467 SUPERFAMILY SSF51905 1 337 2.99E-65 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS13775 d6ef2e34019fe68792e3e649233bed7a 467 Gene3D G3DSA:3.50.50.60 4 144 8.1E-39 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS13775 d6ef2e34019fe68792e3e649233bed7a 467 PIRSF PIRSF000350 1 463 2.3E-87 T 10-11-2016 A4G23_RS13775 d6ef2e34019fe68792e3e649233bed7a 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 141 150 1.0E-65 T 10-11-2016 A4G23_RS13775 d6ef2e34019fe68792e3e649233bed7a 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 265 279 1.0E-65 T 10-11-2016 A4G23_RS13775 d6ef2e34019fe68792e3e649233bed7a 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 431 451 1.0E-65 T 10-11-2016 A4G23_RS13775 d6ef2e34019fe68792e3e649233bed7a 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 1.0E-65 T 10-11-2016 A4G23_RS13775 d6ef2e34019fe68792e3e649233bed7a 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 176 201 1.0E-65 T 10-11-2016 A4G23_RS13775 d6ef2e34019fe68792e3e649233bed7a 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 409 424 1.0E-65 T 10-11-2016 A4G23_RS13775 d6ef2e34019fe68792e3e649233bed7a 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 1.0E-65 T 10-11-2016 A4G23_RS13775 d6ef2e34019fe68792e3e649233bed7a 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 344 365 1.0E-65 T 10-11-2016 A4G23_RS13775 d6ef2e34019fe68792e3e649233bed7a 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 308 315 1.0E-65 T 10-11-2016 A4G23_RS13775 d6ef2e34019fe68792e3e649233bed7a 467 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 5 466 9.3E-171 T 10-11-2016 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 A4G23_RS01495 04eac5a927d1aa1dc87e96c3aafd94aa 414 Pfam PF00999 Sodium/hydrogen exchanger family 19 371 1.3E-45 T 10-11-2016 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A4G23_RS26645 39301107fd1644af736fc6d5c0500464 271 Pfam PF12833 Helix-turn-helix domain 170 244 2.0E-14 T 10-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4G23_RS26645 39301107fd1644af736fc6d5c0500464 271 SUPERFAMILY SSF46689 200 246 1.21E-6 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS26645 39301107fd1644af736fc6d5c0500464 271 Gene3D G3DSA:1.10.10.60 202 244 6.9E-6 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS26645 39301107fd1644af736fc6d5c0500464 271 Gene3D G3DSA:1.10.10.60 148 201 2.8E-5 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS26645 39301107fd1644af736fc6d5c0500464 271 SMART SM00342 164 247 8.0E-7 T 10-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4G23_RS19715 7b3bba6881c6132c473ec7ec1ede190e 114 Pfam PF12823 Domain of unknown function (DUF3817) 9 95 1.7E-23 T 10-11-2016 IPR023845 Domain of unknown function DUF3817, transmembrane A4G23_RS19715 7b3bba6881c6132c473ec7ec1ede190e 114 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 13 93 1.3E-23 T 10-11-2016 IPR023845 Domain of unknown function DUF3817, transmembrane A4G23_RS16750 a86161eb34385d6d0e25c3bbaff6a34d 287 PIRSF PIRSF001430 10 276 3.7E-73 T 10-11-2016 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4G23_RS16750 a86161eb34385d6d0e25c3bbaff6a34d 287 Gene3D G3DSA:3.30.70.580 10 119 5.2E-33 T 10-11-2016 IPR020094 Pseudouridine synthase I, TruA, N-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4G23_RS16750 a86161eb34385d6d0e25c3bbaff6a34d 287 Pfam PF01416 tRNA pseudouridine synthase 158 260 1.6E-23 T 10-11-2016 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4G23_RS16750 a86161eb34385d6d0e25c3bbaff6a34d 287 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 10 259 30.309 T 10-11-2016 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4G23_RS16750 a86161eb34385d6d0e25c3bbaff6a34d 287 SUPERFAMILY SSF55120 9 266 5.47E-71 T 10-11-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4G23_RS16750 a86161eb34385d6d0e25c3bbaff6a34d 287 Gene3D G3DSA:3.30.70.660 121 257 3.9E-36 T 10-11-2016 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4G23_RS16750 a86161eb34385d6d0e25c3bbaff6a34d 287 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 12 253 2.8E-47 T 10-11-2016 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4G23_RS15235 b5dc4ed28f40b7e9cbde75a3be8c6fd4 235 Pfam PF09335 SNARE associated Golgi protein 39 167 2.9E-25 T 10-11-2016 IPR032816 SNARE associated Golgi protein A4G23_RS23685 69e4f35b81aab979b8be878090288661 276 Gene3D G3DSA:1.10.3480.10 29 154 1.3E-7 T 10-11-2016 IPR020945 DMSO/Nitrate reductase chaperone A4G23_RS23685 69e4f35b81aab979b8be878090288661 276 Pfam PF02613 Nitrate reductase delta subunit 74 184 1.5E-11 T 10-11-2016 IPR020945 DMSO/Nitrate reductase chaperone A4G23_RS23685 69e4f35b81aab979b8be878090288661 276 TIGRFAM TIGR00684 narJ: nitrate reductase molybdenum cofactor assembly chaperone 42 193 5.2E-34 T 10-11-2016 IPR003765 Nitrate reductase chaperone, NarJ GO:0051082|GO:0051131 A4G23_RS23685 69e4f35b81aab979b8be878090288661 276 SUPERFAMILY SSF89155 34 198 1.02E-28 T 10-11-2016 IPR020945 DMSO/Nitrate reductase chaperone A4G23_RS22700 f58f38b6267fec5df381730df7613da6 509 Pfam PF08242 Methyltransferase domain 303 404 1.5E-12 T 10-11-2016 IPR013217 Methyltransferase type 12 A4G23_RS22700 f58f38b6267fec5df381730df7613da6 509 TIGRFAM TIGR04074 bacter_Hen1: 3' terminal RNA ribose 2'-O-methyltransferase Hen1 3 477 4.4E-211 T 10-11-2016 IPR024026 3'-RNA ribose 2'-O-methyltransferase, Hen1, bacterial A4G23_RS22700 f58f38b6267fec5df381730df7613da6 509 SUPERFAMILY SSF53335 279 446 3.35E-22 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS22700 f58f38b6267fec5df381730df7613da6 509 Pfam PF12623 RNA repair, ligase-Pnkp-associating, region of Hen1 1 249 3.2E-114 T 10-11-2016 IPR024740 Hen1, N-terminal A4G23_RS22700 f58f38b6267fec5df381730df7613da6 509 Gene3D G3DSA:3.40.50.150 286 457 1.2E-21 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS18930 c16495cbc3a73a697548589e71774d6c 222 TIGRFAM TIGR02947 SigH_actino: RNA polymerase sigma-70 factor, TIGR02947 family 21 207 1.8E-107 T 10-11-2016 IPR014293 RNA polymerase sigma-70, actinobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS18930 c16495cbc3a73a697548589e71774d6c 222 Pfam PF08281 Sigma-70, region 4 143 192 1.8E-13 T 10-11-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS18930 c16495cbc3a73a697548589e71774d6c 222 Gene3D G3DSA:1.10.1740.10 26 102 2.3E-29 T 10-11-2016 A4G23_RS18930 c16495cbc3a73a697548589e71774d6c 222 SUPERFAMILY SSF88659 135 197 5.42E-16 T 10-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS18930 c16495cbc3a73a697548589e71774d6c 222 SUPERFAMILY SSF88946 29 115 1.05E-24 T 10-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS18930 c16495cbc3a73a697548589e71774d6c 222 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 55 86 - T 10-11-2016 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS18930 c16495cbc3a73a697548589e71774d6c 222 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 35 195 5.9E-27 T 10-11-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS18930 c16495cbc3a73a697548589e71774d6c 222 Pfam PF04542 Sigma-70 region 2 37 100 3.8E-19 T 10-11-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS18930 c16495cbc3a73a697548589e71774d6c 222 Gene3D G3DSA:1.10.10.10 135 199 6.5E-24 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS23070 2cf7718431cf8dc2fb9228dc2efaf0c8 183 Pfam PF08044 Domain of unknown function (DUF1707) 13 63 1.9E-13 T 10-11-2016 IPR012551 Protein of unknown function DUF1707 A4G23_RS23070 2cf7718431cf8dc2fb9228dc2efaf0c8 183 SMART SM00240 109 159 7.7E-12 T 10-11-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 A4G23_RS23070 2cf7718431cf8dc2fb9228dc2efaf0c8 183 Pfam PF00498 FHA domain 111 174 6.1E-17 T 10-11-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 A4G23_RS23070 2cf7718431cf8dc2fb9228dc2efaf0c8 183 SUPERFAMILY SSF49879 95 180 8.61E-24 T 10-11-2016 IPR008984 SMAD/FHA domain GO:0005515 A4G23_RS23070 2cf7718431cf8dc2fb9228dc2efaf0c8 183 Gene3D G3DSA:2.60.200.20 107 180 1.9E-23 T 10-11-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 A4G23_RS09115 081ea3ff4433ee75c8170870569d7dc0 585 SUPERFAMILY SSF69318 105 374 2.75E-13 T 10-11-2016 A4G23_RS09115 081ea3ff4433ee75c8170870569d7dc0 585 SUPERFAMILY SSF69318 456 530 2.75E-13 T 10-11-2016 A4G23_RS09115 081ea3ff4433ee75c8170870569d7dc0 585 Gene3D G3DSA:2.130.10.130 101 356 1.4E-7 T 10-11-2016 A4G23_RS10205 7b2f78927a778d3789d3ceda82db417f 122 SUPERFAMILY SSF52091 15 120 1.24E-25 T 10-11-2016 IPR002645 STAS domain A4G23_RS10205 7b2f78927a778d3789d3ceda82db417f 122 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 14 117 1.2E-23 T 10-11-2016 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 A4G23_RS10205 7b2f78927a778d3789d3ceda82db417f 122 Gene3D G3DSA:3.30.750.24 15 120 8.2E-34 T 10-11-2016 IPR002645 STAS domain A4G23_RS10205 7b2f78927a778d3789d3ceda82db417f 122 Pfam PF13466 STAS domain 30 105 6.7E-19 T 10-11-2016 IPR002645 STAS domain A4G23_RS13210 179a124cbc616e8b9615936aedce39bb 331 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 87 4.8E-7 T 10-11-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A4G23_RS13210 179a124cbc616e8b9615936aedce39bb 331 Gene3D G3DSA:3.40.50.720 147 259 5.3E-31 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS13210 179a124cbc616e8b9615936aedce39bb 331 Gene3D G3DSA:3.90.180.10 1 146 9.8E-48 T 10-11-2016 IPR011032 GroES-like A4G23_RS13210 179a124cbc616e8b9615936aedce39bb 331 SUPERFAMILY SSF51735 111 287 1.01E-48 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS13210 179a124cbc616e8b9615936aedce39bb 331 Pfam PF00107 Zinc-binding dehydrogenase 151 266 2.2E-26 T 10-11-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A4G23_RS13210 179a124cbc616e8b9615936aedce39bb 331 SMART SM00829 10 323 1.7E-48 T 10-11-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A4G23_RS13210 179a124cbc616e8b9615936aedce39bb 331 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 1 324 2.4E-141 T 10-11-2016 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 A4G23_RS13210 179a124cbc616e8b9615936aedce39bb 331 SUPERFAMILY SSF50129 1 140 1.38E-38 T 10-11-2016 IPR011032 GroES-like A4G23_RS04090 0cc41c16e1de0c1a0c6d016271b27d47 357 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 127 329 3.3E-34 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS04090 0cc41c16e1de0c1a0c6d016271b27d47 357 SMART SM00331 101 330 6.4E-24 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS20345 6fe5d584cd5e05f124428855dc828708 233 Pfam PF01983 Guanylyl transferase CofC like 24 184 8.7E-10 T 10-11-2016 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 A4G23_RS20345 6fe5d584cd5e05f124428855dc828708 233 Gene3D G3DSA:3.90.550.10 24 190 1.4E-25 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS20345 6fe5d584cd5e05f124428855dc828708 233 TIGRFAM TIGR03552 F420_cofC: 2-phospho-L-lactate guanylyltransferase 24 218 6.3E-50 T 10-11-2016 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 A4G23_RS20345 6fe5d584cd5e05f124428855dc828708 233 Hamap MF_02114 2-phospho-L-lactate guanylyltransferase [cofC]. 22 226 22.511 T 10-11-2016 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 A4G23_RS20345 6fe5d584cd5e05f124428855dc828708 233 SUPERFAMILY SSF53448 24 220 3.01E-30 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS22940 28f9b11cdbe1caf879e92488f03617f5 225 Pfam PF11452 Protein of unknown function (DUF3000) 28 201 3.8E-70 T 10-11-2016 IPR021555 Protein of unknown function DUF3000 A4G23_RS23655 d9ead3feccf7a70a4446ed371a9b0181 483 Pfam PF13520 Amino acid permease 40 460 6.6E-55 T 10-11-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A4G23_RS23655 d9ead3feccf7a70a4446ed371a9b0181 483 PIRSF PIRSF006060 19 480 1.1E-88 T 10-11-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A4G23_RS19305 a74a5fa2e97cf650f92bf290399e9f67 379 Pfam PF00877 NlpC/P60 family 243 330 3.9E-12 T 10-11-2016 IPR000064 Endopeptidase, NLPC/P60 domain A4G23_RS19305 a74a5fa2e97cf650f92bf290399e9f67 379 SUPERFAMILY SSF54001 227 332 1.77E-27 T 10-11-2016 A4G23_RS19305 a74a5fa2e97cf650f92bf290399e9f67 379 Gene3D G3DSA:3.90.1720.10 226 332 1.2E-29 T 10-11-2016 IPR000064 Endopeptidase, NLPC/P60 domain A4G23_RS24745 9512f49f5fb031ba0f54508e2d69c2ac 404 SUPERFAMILY SSF53901 3 278 1.85E-62 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS24745 9512f49f5fb031ba0f54508e2d69c2ac 404 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 402 4.6E-135 T 10-11-2016 IPR002155 Thiolase GO:0008152|GO:0016747 A4G23_RS24745 9512f49f5fb031ba0f54508e2d69c2ac 404 SUPERFAMILY SSF53901 282 403 2.39E-44 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS24745 9512f49f5fb031ba0f54508e2d69c2ac 404 ProSitePatterns PS00099 Thiolases active site. 385 398 - T 10-11-2016 IPR020610 Thiolase, active site GO:0008152|GO:0016747 A4G23_RS24745 9512f49f5fb031ba0f54508e2d69c2ac 404 PIRSF PIRSF000429 1 404 6.7E-110 T 10-11-2016 IPR002155 Thiolase GO:0008152|GO:0016747 A4G23_RS24745 9512f49f5fb031ba0f54508e2d69c2ac 404 ProSitePatterns PS00737 Thiolases signature 2. 350 366 - T 10-11-2016 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 A4G23_RS24745 9512f49f5fb031ba0f54508e2d69c2ac 404 Pfam PF00108 Thiolase, N-terminal domain 7 231 1.9E-44 T 10-11-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 A4G23_RS24745 9512f49f5fb031ba0f54508e2d69c2ac 404 Pfam PF02803 Thiolase, C-terminal domain 282 403 7.4E-47 T 10-11-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 A4G23_RS24745 9512f49f5fb031ba0f54508e2d69c2ac 404 Gene3D G3DSA:3.40.47.10 145 186 2.5E-58 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS24745 9512f49f5fb031ba0f54508e2d69c2ac 404 Gene3D G3DSA:3.40.47.10 288 403 2.5E-58 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS24745 9512f49f5fb031ba0f54508e2d69c2ac 404 Gene3D G3DSA:3.40.47.10 5 128 1.4E-55 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS24745 9512f49f5fb031ba0f54508e2d69c2ac 404 Gene3D G3DSA:3.40.47.10 187 287 1.4E-55 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS22370 d9c3b5375eee0ba8d404ae078cbaa13d 641 Pfam PF02624 YcaO cyclodehydratase, ATP-ad Mg2+-binding 255 596 5.4E-83 T 10-11-2016 IPR003776 YcaO-like domain A4G23_RS22370 d9c3b5375eee0ba8d404ae078cbaa13d 641 TIGRFAM TIGR03604 TOMM_cyclo_SagD: thiazole/oxazole-forming peptide maturase, SagD family component 260 641 7.6E-97 T 10-11-2016 IPR027624 Thiazole/oxazole-forming peptide maturase, SagD family component A4G23_RS22370 d9c3b5375eee0ba8d404ae078cbaa13d 641 TIGRFAM TIGR03882 cyclo_dehyd_2: bacteriocin biosynthesis cyclodehydratase domain 46 219 1.4E-22 T 10-11-2016 IPR022291 Bacteriocin biosynthesis, cyclodehydratase domain A4G23_RS00450 4ac25d4766d99f6d4f2fd00673861d9c 319 TIGRFAM TIGR03707 PPK2_P_aer: polyphosphate kinase 2 51 278 1.4E-113 T 10-11-2016 IPR022486 Polyphosphate kinase 2, PA0141 GO:0006793|GO:0008976 A4G23_RS00450 4ac25d4766d99f6d4f2fd00673861d9c 319 Gene3D G3DSA:3.40.50.300 43 296 1.3E-105 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS00450 4ac25d4766d99f6d4f2fd00673861d9c 319 SUPERFAMILY SSF52540 82 268 7.2E-28 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS00450 4ac25d4766d99f6d4f2fd00673861d9c 319 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 51 277 9.9E-102 T 10-11-2016 IPR022488 Polyphosphate kinase-2-related A4G23_RS20005 2fc7e3b3d1b715703327920630762bb9 226 Pfam PF03458 UPF0126 domain 14 87 1.2E-18 T 10-11-2016 IPR005115 Uncharacterised domain UPF0126 A4G23_RS20005 2fc7e3b3d1b715703327920630762bb9 226 Pfam PF03458 UPF0126 domain 99 173 1.6E-20 T 10-11-2016 IPR005115 Uncharacterised domain UPF0126 A4G23_RS17680 77df02cf9165affbb03be5c554f9a673 212 PRINTS PR00988 Uridine kinase signature 79 94 6.0E-7 T 10-11-2016 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 A4G23_RS17680 77df02cf9165affbb03be5c554f9a673 212 PRINTS PR00988 Uridine kinase signature 139 149 6.0E-7 T 10-11-2016 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 A4G23_RS17680 77df02cf9165affbb03be5c554f9a673 212 PRINTS PR00988 Uridine kinase signature 8 25 6.0E-7 T 10-11-2016 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 A4G23_RS17680 77df02cf9165affbb03be5c554f9a673 212 Gene3D G3DSA:3.40.50.300 9 173 2.8E-22 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS17680 77df02cf9165affbb03be5c554f9a673 212 SUPERFAMILY SSF52540 9 174 2.78E-10 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS07775 0061a8c23e8270e801bd0ca0ff73f7bf 385 Pfam PF05787 Bacterial protein of unknown function (DUF839) 108 147 2.2E-7 T 10-11-2016 IPR008557 Protein of unknown function DUF839 A4G23_RS07775 0061a8c23e8270e801bd0ca0ff73f7bf 385 Pfam PF05787 Bacterial protein of unknown function (DUF839) 150 242 3.0E-15 T 10-11-2016 IPR008557 Protein of unknown function DUF839 A4G23_RS07775 0061a8c23e8270e801bd0ca0ff73f7bf 385 Pfam PF07676 WD40-like Beta Propeller Repeat 349 371 1.3E-7 T 10-11-2016 IPR011659 WD40-like Beta Propeller A4G23_RS07775 0061a8c23e8270e801bd0ca0ff73f7bf 385 SUPERFAMILY SSF63825 251 365 2.2E-15 T 10-11-2016 A4G23_RS07775 0061a8c23e8270e801bd0ca0ff73f7bf 385 SUPERFAMILY SSF63825 150 208 2.2E-15 T 10-11-2016 A4G23_RS07775 0061a8c23e8270e801bd0ca0ff73f7bf 385 Gene3D G3DSA:2.120.10.30 317 366 9.2E-6 T 10-11-2016 IPR011042 Six-bladed beta-propeller, TolB-like A4G23_RS07775 0061a8c23e8270e801bd0ca0ff73f7bf 385 Gene3D G3DSA:2.130.10.10 261 289 1.9E-4 T 10-11-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 A4G23_RS14925 0cb250a7e93613b50c8fc84b0cf844bc 66 Pfam PF14029 Protein of unknown function (DUF4244) 13 63 9.4E-26 T 10-11-2016 IPR025338 Protein of unknown function DUF4244 A4G23_RS18075 cc716186313b3f110444e52699faf29f 450 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 321 334 3.2E-11 T 10-11-2016 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 A4G23_RS18075 cc716186313b3f110444e52699faf29f 450 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 180 194 3.2E-11 T 10-11-2016 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 A4G23_RS18075 cc716186313b3f110444e52699faf29f 450 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 155 167 3.2E-11 T 10-11-2016 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 A4G23_RS18075 cc716186313b3f110444e52699faf29f 450 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 262 270 3.2E-11 T 10-11-2016 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 A4G23_RS18075 cc716186313b3f110444e52699faf29f 450 Pfam PF00246 Zinc carboxypeptidase 136 423 8.6E-69 T 10-11-2016 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 A4G23_RS18075 cc716186313b3f110444e52699faf29f 450 SUPERFAMILY SSF53187 127 432 7.33E-82 T 10-11-2016 A4G23_RS18075 cc716186313b3f110444e52699faf29f 450 SMART SM00631 129 420 1.5E-96 T 10-11-2016 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 A4G23_RS18075 cc716186313b3f110444e52699faf29f 450 ProSitePatterns PS00133 Zinc carboxypeptidases, zinc-binding region 2 signature. 324 334 - T 10-11-2016 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 A4G23_RS18075 cc716186313b3f110444e52699faf29f 450 Gene3D G3DSA:3.40.630.10 126 438 3.0E-97 T 10-11-2016 A4G23_RS18075 cc716186313b3f110444e52699faf29f 450 ProSitePatterns PS00132 Zinc carboxypeptidases, zinc-binding region 1 signature. 180 202 - T 10-11-2016 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 A4G23_RS22730 1a80866739cae30661165561c1b86b54 829 Gene3D G3DSA:2.60.40.10 491 575 8.5E-4 T 10-11-2016 IPR013783 Immunoglobulin-like fold A4G23_RS22730 1a80866739cae30661165561c1b86b54 829 Gene3D G3DSA:3.40.50.410 47 260 3.3E-14 T 10-11-2016 IPR002035 von Willebrand factor, type A A4G23_RS22730 1a80866739cae30661165561c1b86b54 829 SMART SM00327 48 250 4.5E-9 T 10-11-2016 IPR002035 von Willebrand factor, type A A4G23_RS22730 1a80866739cae30661165561c1b86b54 829 Pfam PF00092 von Willebrand factor type A domain 50 229 9.4E-10 T 10-11-2016 IPR002035 von Willebrand factor, type A A4G23_RS22730 1a80866739cae30661165561c1b86b54 829 SUPERFAMILY SSF53300 48 230 3.12E-18 T 10-11-2016 IPR002035 von Willebrand factor, type A A4G23_RS09420 40eb5c8dcf3e0343875049e8714bac75 243 Pfam PF01138 3' exoribonuclease family, domain 1 11 141 9.7E-24 T 10-11-2016 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A4G23_RS09420 40eb5c8dcf3e0343875049e8714bac75 243 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 3 239 1.6E-116 T 10-11-2016 IPR002381 Ribonuclease phosphorolytic, bacterial-type GO:0000049|GO:0004549|GO:0008033 A4G23_RS09420 40eb5c8dcf3e0343875049e8714bac75 243 Pfam PF03725 3' exoribonuclease family, domain 2 162 225 1.2E-11 T 10-11-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A4G23_RS09420 40eb5c8dcf3e0343875049e8714bac75 243 Hamap MF_00564 Ribonuclease PH [rph]. 2 240 47.353 T 10-11-2016 IPR002381 Ribonuclease phosphorolytic, bacterial-type GO:0000049|GO:0004549|GO:0008033 A4G23_RS09420 40eb5c8dcf3e0343875049e8714bac75 243 SUPERFAMILY SSF55666 156 240 1.27E-25 T 10-11-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A4G23_RS09420 40eb5c8dcf3e0343875049e8714bac75 243 Gene3D G3DSA:3.30.230.70 2 240 8.8E-33 T 10-11-2016 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A4G23_RS09420 40eb5c8dcf3e0343875049e8714bac75 243 ProSitePatterns PS01277 Ribonuclease PH signature. 117 130 - T 10-11-2016 IPR018336 Ribonuclease PH, conserved site A4G23_RS09420 40eb5c8dcf3e0343875049e8714bac75 243 SUPERFAMILY SSF54211 3 183 1.92E-46 T 10-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold A4G23_RS11445 6ece014ce0f2de0bda96313cbb0cac65 283 SUPERFAMILY SSF53328 87 282 5.36E-64 T 10-11-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A4G23_RS11445 6ece014ce0f2de0bda96313cbb0cac65 283 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 6 282 6.1E-104 T 10-11-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 A4G23_RS11445 6ece014ce0f2de0bda96313cbb0cac65 283 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 2 282 48.499 T 10-11-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 A4G23_RS11445 6ece014ce0f2de0bda96313cbb0cac65 283 SUPERFAMILY SSF55021 4 84 3.83E-19 T 10-11-2016 A4G23_RS11445 6ece014ce0f2de0bda96313cbb0cac65 283 Gene3D G3DSA:3.30.70.260 1 83 2.2E-30 T 10-11-2016 A4G23_RS11445 6ece014ce0f2de0bda96313cbb0cac65 283 PIRSF PIRSF036480 2 283 2.1E-115 T 10-11-2016 A4G23_RS11445 6ece014ce0f2de0bda96313cbb0cac65 283 Pfam PF00551 Formyl transferase 87 264 2.7E-39 T 10-11-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A4G23_RS11445 6ece014ce0f2de0bda96313cbb0cac65 283 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 110 137 6.9E-52 T 10-11-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 A4G23_RS11445 6ece014ce0f2de0bda96313cbb0cac65 283 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 256 281 6.9E-52 T 10-11-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 A4G23_RS11445 6ece014ce0f2de0bda96313cbb0cac65 283 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 7 33 6.9E-52 T 10-11-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 A4G23_RS11445 6ece014ce0f2de0bda96313cbb0cac65 283 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 234 256 6.9E-52 T 10-11-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 A4G23_RS11445 6ece014ce0f2de0bda96313cbb0cac65 283 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 88 110 6.9E-52 T 10-11-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 A4G23_RS11445 6ece014ce0f2de0bda96313cbb0cac65 283 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 39 51 6.9E-52 T 10-11-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 A4G23_RS11445 6ece014ce0f2de0bda96313cbb0cac65 283 Gene3D G3DSA:3.40.50.170 87 282 1.2E-56 T 10-11-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A4G23_RS24875 d656a1fe74d777551b159b673b2faa36 290 Gene3D G3DSA:3.90.550.10 6 226 2.9E-24 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS24875 d656a1fe74d777551b159b673b2faa36 290 SUPERFAMILY SSF53448 5 219 3.56E-34 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS24875 d656a1fe74d777551b159b673b2faa36 290 Pfam PF00535 Glycosyl transferase family 2 6 162 7.6E-10 T 10-11-2016 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A4G23_RS10465 8a4750f049080ba880c6451060db8de7 249 SUPERFAMILY SSF55729 20 148 2.48E-8 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS10465 8a4750f049080ba880c6451060db8de7 249 Gene3D G3DSA:3.40.630.30 13 147 8.9E-7 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS02890 48e7d721af69b402ece3a1bed95e223f 434 SUPERFAMILY SSF103473 18 404 7.19E-38 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS02890 48e7d721af69b402ece3a1bed95e223f 434 Pfam PF07690 Major Facilitator Superfamily 27 356 3.4E-27 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS02890 48e7d721af69b402ece3a1bed95e223f 434 Gene3D G3DSA:1.20.1250.20 23 201 7.2E-21 T 10-11-2016 A4G23_RS02890 48e7d721af69b402ece3a1bed95e223f 434 Gene3D G3DSA:1.20.1250.20 229 405 6.0E-8 T 10-11-2016 A4G23_RS11135 c741c9e69cb2ed91648aabb4a71235e7 269 Gene3D G3DSA:3.40.50.300 3 227 1.9E-64 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS11135 c741c9e69cb2ed91648aabb4a71235e7 269 Pfam PF00005 ABC transporter 21 167 1.0E-29 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS11135 c741c9e69cb2ed91648aabb4a71235e7 269 SUPERFAMILY SSF52540 3 224 2.05E-62 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS11135 c741c9e69cb2ed91648aabb4a71235e7 269 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS11135 c741c9e69cb2ed91648aabb4a71235e7 269 SMART SM00382 27 212 6.4E-14 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS13305 03b308debd7bc08ef28e7fa48fdb4a74 114 Gene3D G3DSA:3.40.250.10 16 106 8.1E-26 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS13305 03b308debd7bc08ef28e7fa48fdb4a74 114 SUPERFAMILY SSF52821 15 105 5.63E-28 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS13305 03b308debd7bc08ef28e7fa48fdb4a74 114 Pfam PF00581 Rhodanese-like domain 18 98 1.8E-12 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS13305 03b308debd7bc08ef28e7fa48fdb4a74 114 SMART SM00450 4 102 2.8E-19 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS05845 d8f5aca7728a5597e5b91b287c5eddbf 897 Pfam PF08482 ATP-dependent helicase C-terminal 753 884 1.3E-47 T 10-11-2016 IPR013689 ATP-dependent RNA helicase HrpB, C-terminal A4G23_RS05845 d8f5aca7728a5597e5b91b287c5eddbf 897 Pfam PF00271 Helicase conserved C-terminal domain 221 335 1.7E-10 T 10-11-2016 IPR001650 Helicase, C-terminal A4G23_RS05845 d8f5aca7728a5597e5b91b287c5eddbf 897 SUPERFAMILY SSF52540 20 165 5.66E-46 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05845 d8f5aca7728a5597e5b91b287c5eddbf 897 SUPERFAMILY SSF52540 192 346 5.66E-46 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05845 d8f5aca7728a5597e5b91b287c5eddbf 897 Gene3D G3DSA:3.40.50.300 218 350 1.9E-11 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05845 d8f5aca7728a5597e5b91b287c5eddbf 897 SMART SM00487 7 189 1.7E-19 T 10-11-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4G23_RS05845 d8f5aca7728a5597e5b91b287c5eddbf 897 Gene3D G3DSA:3.40.50.300 9 164 5.7E-52 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05845 d8f5aca7728a5597e5b91b287c5eddbf 897 Pfam PF00270 DEAD/DEAH box helicase 20 162 2.6E-6 T 10-11-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A4G23_RS05845 d8f5aca7728a5597e5b91b287c5eddbf 897 SMART SM00847 397 490 1.0E-9 T 10-11-2016 IPR007502 Helicase-associated domain GO:0004386 A4G23_RS05845 d8f5aca7728a5597e5b91b287c5eddbf 897 Pfam PF04408 Helicase associated domain (HA2) 398 478 2.2E-9 T 10-11-2016 IPR007502 Helicase-associated domain GO:0004386 A4G23_RS05845 d8f5aca7728a5597e5b91b287c5eddbf 897 SMART SM00490 239 337 1.3E-11 T 10-11-2016 IPR001650 Helicase, C-terminal A4G23_RS09180 6b70a65dc52ec7caaaba6236bc35e836 290 SUPERFAMILY SSF53335 33 245 1.15E-30 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS09180 6b70a65dc52ec7caaaba6236bc35e836 290 Gene3D G3DSA:3.40.50.150 24 278 1.8E-66 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS09180 6b70a65dc52ec7caaaba6236bc35e836 290 Pfam PF01564 Spermine/spermidine synthase 59 187 1.9E-5 T 10-11-2016 A4G23_RS16895 2317389041464f0f69c9bc2671c6b6a0 368 SUPERFAMILY SSF53067 6 316 1.51E-38 T 10-11-2016 A4G23_RS16895 2317389041464f0f69c9bc2671c6b6a0 368 Gene3D G3DSA:3.30.420.40 6 162 8.6E-46 T 10-11-2016 A4G23_RS16895 2317389041464f0f69c9bc2671c6b6a0 368 ProSitePatterns PS01016 Glycoprotease family signature. 99 119 - T 10-11-2016 IPR017860 Peptidase M22, conserved site KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618|Reactome: R-HSA-6782315 A4G23_RS16895 2317389041464f0f69c9bc2671c6b6a0 368 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 271 280 8.1E-51 T 10-11-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A4G23_RS16895 2317389041464f0f69c9bc2671c6b6a0 368 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 134 146 8.1E-51 T 10-11-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A4G23_RS16895 2317389041464f0f69c9bc2671c6b6a0 368 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 158 179 8.1E-51 T 10-11-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A4G23_RS16895 2317389041464f0f69c9bc2671c6b6a0 368 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 8 21 8.1E-51 T 10-11-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A4G23_RS16895 2317389041464f0f69c9bc2671c6b6a0 368 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 100 119 8.1E-51 T 10-11-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A4G23_RS16895 2317389041464f0f69c9bc2671c6b6a0 368 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 79 99 8.1E-51 T 10-11-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A4G23_RS16895 2317389041464f0f69c9bc2671c6b6a0 368 Pfam PF00814 Glycoprotease family 27 314 4.3E-98 T 10-11-2016 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A4G23_RS16895 2317389041464f0f69c9bc2671c6b6a0 368 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 7 321 3.0E-127 T 10-11-2016 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A4G23_RS16895 2317389041464f0f69c9bc2671c6b6a0 368 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 8 314 3.0E-99 T 10-11-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A4G23_RS16895 2317389041464f0f69c9bc2671c6b6a0 368 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 5 340 62.28 T 10-11-2016 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A4G23_RS21605 176615172b738c8496f8ba274fd07994 287 Gene3D G3DSA:3.90.1200.10 94 240 1.4E-15 T 10-11-2016 A4G23_RS21605 176615172b738c8496f8ba274fd07994 287 Pfam PF01636 Phosphotransferase enzyme family 38 242 9.7E-24 T 10-11-2016 IPR002575 Aminoglycoside phosphotransferase A4G23_RS21605 176615172b738c8496f8ba274fd07994 287 SUPERFAMILY SSF56112 8 247 1.46E-27 T 10-11-2016 IPR011009 Protein kinase-like domain A4G23_RS24605 182f0db75ad7f3f528cba4e5f0454b52 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 3.2E-9 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS24605 182f0db75ad7f3f528cba4e5f0454b52 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 3.2E-9 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS24605 182f0db75ad7f3f528cba4e5f0454b52 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 7.8E-16 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS24605 182f0db75ad7f3f528cba4e5f0454b52 209 SUPERFAMILY SSF48498 86 198 7.63E-14 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS24605 182f0db75ad7f3f528cba4e5f0454b52 209 SUPERFAMILY SSF46689 8 89 9.48E-20 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS24605 182f0db75ad7f3f528cba4e5f0454b52 209 Gene3D G3DSA:1.10.357.10 9 198 2.2E-39 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS24605 182f0db75ad7f3f528cba4e5f0454b52 209 Pfam PF13977 Bacterial transcriptional repressor 126 191 5.9E-7 T 10-11-2016 A4G23_RS22000 0e557fb03baefa848fb4fd76d13e6e60 435 Pfam PF13416 Bacterial extracellular solute-binding protein 62 364 3.2E-31 T 10-11-2016 A4G23_RS22000 0e557fb03baefa848fb4fd76d13e6e60 435 SUPERFAMILY SSF53850 42 430 8.4E-57 T 10-11-2016 A4G23_RS22000 0e557fb03baefa848fb4fd76d13e6e60 435 Gene3D G3DSA:3.40.190.10 162 362 2.0E-28 T 10-11-2016 A4G23_RS16110 af5a4392caacf0c90767e81516bd4cff 549 Pfam PF00361 Proton-conducting membrane transporter 179 485 2.9E-72 T 10-11-2016 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16110 af5a4392caacf0c90767e81516bd4cff 549 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 25 538 17.998 T 10-11-2016 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 A4G23_RS16110 af5a4392caacf0c90767e81516bd4cff 549 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 154 537 1.3E-112 T 10-11-2016 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 A4G23_RS17940 6ba27bdafcda6abaf94caec235734f6d 183 SUPERFAMILY SSF88659 95 144 6.17E-9 T 10-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS17940 6ba27bdafcda6abaf94caec235734f6d 183 Gene3D G3DSA:1.10.10.10 95 143 3.2E-6 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS17940 6ba27bdafcda6abaf94caec235734f6d 183 Pfam PF04545 Sigma-70, region 4 95 142 2.0E-6 T 10-11-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS00985 6d44f08295790223d3eccb230c1fa99e 674 SUPERFAMILY SSF51735 111 180 4.63E-10 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS00985 6d44f08295790223d3eccb230c1fa99e 674 Gene3D G3DSA:3.40.50.720 423 575 1.5E-30 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS00985 6d44f08295790223d3eccb230c1fa99e 674 Gene3D G3DSA:3.40.50.720 114 181 1.8E-16 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS00985 6d44f08295790223d3eccb230c1fa99e 674 Gene3D G3DSA:3.40.50.720 1 47 1.8E-16 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS00985 6d44f08295790223d3eccb230c1fa99e 674 Pfam PF02254 TrkA-N domain 426 534 8.8E-20 T 10-11-2016 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 A4G23_RS00985 6d44f08295790223d3eccb230c1fa99e 674 Pfam PF02254 TrkA-N domain 113 181 4.4E-9 T 10-11-2016 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 A4G23_RS00985 6d44f08295790223d3eccb230c1fa99e 674 SUPERFAMILY SSF51735 422 536 5.45E-23 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS01670 850d6a60464849a2bbe41348a55d0e60 281 SUPERFAMILY SSF161098 8 281 2.75E-61 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS01670 850d6a60464849a2bbe41348a55d0e60 281 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 272 1.7E-8 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS01670 850d6a60464849a2bbe41348a55d0e60 281 Gene3D G3DSA:1.10.3720.10 8 269 3.8E-55 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS14505 a724961cdd1327ccc9636c3ee5ab25a8 182 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 182 24.682 T 10-11-2016 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|Reactome: R-HSA-500753 A4G23_RS14505 a724961cdd1327ccc9636c3ee5ab25a8 182 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 14 170 3.0E-35 T 10-11-2016 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|Reactome: R-HSA-500753 A4G23_RS14505 a724961cdd1327ccc9636c3ee5ab25a8 182 SUPERFAMILY SSF53271 8 178 3.93E-36 T 10-11-2016 IPR029057 Phosphoribosyltransferase-like A4G23_RS14505 a724961cdd1327ccc9636c3ee5ab25a8 182 Gene3D G3DSA:3.40.50.2020 7 179 1.2E-48 T 10-11-2016 IPR029057 Phosphoribosyltransferase-like A4G23_RS14505 a724961cdd1327ccc9636c3ee5ab25a8 182 Pfam PF00156 Phosphoribosyl transferase domain 63 161 2.5E-11 T 10-11-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 A4G23_RS23710 a4642699fe85be867c06d63598cb6add 159 PIRSF PIRSF005028 1 159 2.5E-59 T 10-11-2016 IPR026278 Potassium/proton antiporter subunit KhtT A4G23_RS23710 a4642699fe85be867c06d63598cb6add 159 Gene3D G3DSA:3.30.70.1450 86 156 3.6E-22 T 10-11-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A4G23_RS23710 a4642699fe85be867c06d63598cb6add 159 SUPERFAMILY SSF116726 85 156 1.96E-18 T 10-11-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A4G23_RS23710 a4642699fe85be867c06d63598cb6add 159 Pfam PF02080 TrkA-C domain 89 156 1.2E-17 T 10-11-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A4G23_RS02345 5e85617a1e2caf2b5a0e2944e344ddb7 144 Pfam PF05523 WxcM-like, C-terminal 16 140 4.1E-45 T 10-11-2016 IPR008894 WxcM-like, C-terminal MetaCyc: PWY-6953|MetaCyc: PWY-7688 A4G23_RS02345 5e85617a1e2caf2b5a0e2944e344ddb7 144 SUPERFAMILY SSF51182 15 138 2.07E-37 T 10-11-2016 IPR011051 RmlC-like cupin domain A4G23_RS25415 f12a5e7328f3298bc109621608b3eec9 251 SMART SM00644 68 231 0.0039 T 10-11-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 A4G23_RS25415 f12a5e7328f3298bc109621608b3eec9 251 Gene3D G3DSA:3.40.80.10 49 247 3.7E-48 T 10-11-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 A4G23_RS25415 f12a5e7328f3298bc109621608b3eec9 251 SUPERFAMILY SSF55846 54 242 5.1E-44 T 10-11-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 A4G23_RS25415 f12a5e7328f3298bc109621608b3eec9 251 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 78 231 7.0E-12 T 10-11-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 A4G23_RS25415 f12a5e7328f3298bc109621608b3eec9 251 SMART SM00701 54 203 2.4E-44 T 10-11-2016 IPR006619 Peptidoglycan recognition protein family domain, metazoa/bacteria GO:0008270|GO:0008745|GO:0009253 A4G23_RS10980 2800e5e529e620cc7a0d53184ce61f6e 178 PRINTS PR00598 Bacterial regulatory protein MarR family signature 91 106 2.8E-11 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS10980 2800e5e529e620cc7a0d53184ce61f6e 178 PRINTS PR00598 Bacterial regulatory protein MarR family signature 110 126 2.8E-11 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS10980 2800e5e529e620cc7a0d53184ce61f6e 178 PRINTS PR00598 Bacterial regulatory protein MarR family signature 141 161 2.8E-11 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS10980 2800e5e529e620cc7a0d53184ce61f6e 178 PRINTS PR00598 Bacterial regulatory protein MarR family signature 74 90 2.8E-11 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS10980 2800e5e529e620cc7a0d53184ce61f6e 178 SUPERFAMILY SSF46785 20 166 1.02E-29 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS10980 2800e5e529e620cc7a0d53184ce61f6e 178 Gene3D G3DSA:1.10.10.10 20 167 1.0E-36 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS10980 2800e5e529e620cc7a0d53184ce61f6e 178 Pfam PF12802 MarR family 54 114 1.8E-12 T 10-11-2016 A4G23_RS10980 2800e5e529e620cc7a0d53184ce61f6e 178 SMART SM00347 48 151 3.3E-18 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS02910 8ee62f979a0c60baddb54275af40998f 290 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 1 276 17.457 T 10-11-2016 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 A4G23_RS02910 8ee62f979a0c60baddb54275af40998f 290 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 7 269 2.8E-73 T 10-11-2016 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 A4G23_RS02910 8ee62f979a0c60baddb54275af40998f 290 Pfam PF02673 Bacitracin resistance protein BacA 7 271 1.6E-74 T 10-11-2016 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 A4G23_RS04845 9dcfecb7b22114baaae9b0919253c2fa 227 SMART SM00563 53 163 1.2E-24 T 10-11-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 A4G23_RS04845 9dcfecb7b22114baaae9b0919253c2fa 227 Gene3D G3DSA:3.40.1130.10 46 163 5.4E-15 T 10-11-2016 A4G23_RS04845 9dcfecb7b22114baaae9b0919253c2fa 227 SUPERFAMILY SSF69593 31 216 1.02E-31 T 10-11-2016 A4G23_RS04845 9dcfecb7b22114baaae9b0919253c2fa 227 Pfam PF01553 Acyltransferase 42 160 3.1E-18 T 10-11-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 A4G23_RS18345 b4e9d84b7b5787ed1e739064ed6cffd2 269 PIRSF PIRSF017393 2 266 2.3E-86 T 10-11-2016 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type A4G23_RS18345 b4e9d84b7b5787ed1e739064ed6cffd2 269 Gene3D G3DSA:3.40.50.150 5 265 3.7E-97 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS18345 b4e9d84b7b5787ed1e739064ed6cffd2 269 SUPERFAMILY SSF53335 12 251 3.03E-39 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS18345 b4e9d84b7b5787ed1e739064ed6cffd2 269 Pfam PF04672 S-adenosyl methyltransferase 4 265 1.6E-89 T 10-11-2016 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type A4G23_RS18250 d48069457839fd6bf74896cdbd96f19f 558 Pfam PF05683 Fumarase C-terminus 333 540 4.8E-93 T 10-11-2016 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 A4G23_RS18250 d48069457839fd6bf74896cdbd96f19f 558 Gene3D G3DSA:3.20.130.10 354 539 2.7E-75 T 10-11-2016 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 A4G23_RS18250 d48069457839fd6bf74896cdbd96f19f 558 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 376 539 4.7E-58 T 10-11-2016 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 A4G23_RS18250 d48069457839fd6bf74896cdbd96f19f 558 PIRSF PIRSF001394 31 553 1.0E-228 T 10-11-2016 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384 A4G23_RS18250 d48069457839fd6bf74896cdbd96f19f 558 SUPERFAMILY SSF117457 364 539 1.57E-62 T 10-11-2016 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 A4G23_RS18250 d48069457839fd6bf74896cdbd96f19f 558 Pfam PF05681 Fumarate hydratase (Fumerase) 50 327 4.2E-89 T 10-11-2016 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 A4G23_RS18250 d48069457839fd6bf74896cdbd96f19f 558 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 58 328 3.8E-34 T 10-11-2016 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 A4G23_RS18250 d48069457839fd6bf74896cdbd96f19f 558 ProSitePatterns PS00163 Fumarate lyases signature. 459 468 - T 10-11-2016 IPR020557 Fumarate lyase, conserved site GO:0003824 A4G23_RS16525 2fc83bf9ef36a10911c3196db23b07be 1063 SUPERFAMILY SSF81631 805 950 8.37E-18 T 10-11-2016 A4G23_RS16525 2fc83bf9ef36a10911c3196db23b07be 1063 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 155 389 1.2E-18 T 10-11-2016 IPR005135 Endonuclease/exonuclease/phosphatase A4G23_RS16525 2fc83bf9ef36a10911c3196db23b07be 1063 SUPERFAMILY SSF56219 151 397 1.83E-31 T 10-11-2016 IPR005135 Endonuclease/exonuclease/phosphatase A4G23_RS16525 2fc83bf9ef36a10911c3196db23b07be 1063 Pfam PF04928 Poly(A) polymerase central domain 789 950 6.2E-11 T 10-11-2016 IPR007012 Poly(A) polymerase, central domain GO:0004652|GO:0043631 A4G23_RS16525 2fc83bf9ef36a10911c3196db23b07be 1063 Gene3D G3DSA:3.90.1140.10 414 586 1.9E-21 T 10-11-2016 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase A4G23_RS16525 2fc83bf9ef36a10911c3196db23b07be 1063 Gene3D G3DSA:1.10.1410.10 754 951 9.3E-24 T 10-11-2016 A4G23_RS16525 2fc83bf9ef36a10911c3196db23b07be 1063 SUPERFAMILY SSF81301 671 762 4.25E-10 T 10-11-2016 A4G23_RS16525 2fc83bf9ef36a10911c3196db23b07be 1063 Gene3D G3DSA:3.60.10.10 152 396 6.3E-9 T 10-11-2016 IPR005135 Endonuclease/exonuclease/phosphatase A4G23_RS16525 2fc83bf9ef36a10911c3196db23b07be 1063 SUPERFAMILY SSF55144 414 581 5.23E-16 T 10-11-2016 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase A4G23_RS16525 2fc83bf9ef36a10911c3196db23b07be 1063 Pfam PF13563 2'-5' RNA ligase superfamily 421 569 4.4E-35 T 10-11-2016 A4G23_RS00540 f7232f8d0d963ef09037f6a252d4377a 243 SUPERFAMILY SSF81296 31 211 3.08E-48 T 10-11-2016 IPR014756 Immunoglobulin E-set A4G23_RS00540 f7232f8d0d963ef09037f6a252d4377a 243 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 31 208 3.5E-40 T 10-11-2016 IPR004302 Chitin-binding protein, N-terminal A4G23_RS00540 f7232f8d0d963ef09037f6a252d4377a 243 Gene3D G3DSA:2.70.50.50 31 209 5.1E-51 T 10-11-2016 A4G23_RS04920 07165e45b33822a51908978d7c8427c5 559 Pfam PF00117 Glutamine amidotransferase class-I 313 547 1.8E-47 T 10-11-2016 IPR017926 Glutamine amidotransferase A4G23_RS04920 07165e45b33822a51908978d7c8427c5 559 SUPERFAMILY SSF52317 300 552 9.32E-71 T 10-11-2016 IPR029062 Class I glutamine amidotransferase-like A4G23_RS04920 07165e45b33822a51908978d7c8427c5 559 Gene3D G3DSA:3.40.50.880 299 553 1.0E-85 T 10-11-2016 IPR029062 Class I glutamine amidotransferase-like A4G23_RS04920 07165e45b33822a51908978d7c8427c5 559 Pfam PF06418 CTP synthase N-terminus 15 278 2.1E-122 T 10-11-2016 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 A4G23_RS04920 07165e45b33822a51908978d7c8427c5 559 TIGRFAM TIGR00337 PyrG: CTP synthase 13 547 2.6E-229 T 10-11-2016 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 A4G23_RS04920 07165e45b33822a51908978d7c8427c5 559 Hamap MF_01227 CTP synthase [pyrG]. 14 552 50.637 T 10-11-2016 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 A4G23_RS04920 07165e45b33822a51908978d7c8427c5 559 SUPERFAMILY SSF52540 14 278 6.44E-118 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS04920 07165e45b33822a51908978d7c8427c5 559 Gene3D G3DSA:3.40.50.300 8 296 2.7E-131 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS07205 95391d622d80f0b26868d94ca0616cef 135 Pfam PF01464 Transglycosylase SLT domain 56 121 3.1E-7 T 10-11-2016 IPR008258 Transglycosylase SLT domain 1 A4G23_RS07205 95391d622d80f0b26868d94ca0616cef 135 SUPERFAMILY SSF53955 62 128 1.83E-10 T 10-11-2016 IPR023346 Lysozyme-like domain A4G23_RS07205 95391d622d80f0b26868d94ca0616cef 135 Gene3D G3DSA:1.10.530.10 59 122 3.2E-7 T 10-11-2016 A4G23_RS17640 ae44e095ca34a5bd8ff47c7c71327d58 385 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 18 354 3.7E-73 T 10-11-2016 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 A4G23_RS17640 ae44e095ca34a5bd8ff47c7c71327d58 385 Gene3D G3DSA:3.20.20.140 14 356 1.6E-103 T 10-11-2016 A4G23_RS17640 ae44e095ca34a5bd8ff47c7c71327d58 385 SUPERFAMILY SSF51556 12 351 3.16E-73 T 10-11-2016 IPR032466 Metal-dependent hydrolase A4G23_RS17640 ae44e095ca34a5bd8ff47c7c71327d58 385 Hamap MF_00540 Adenosine deaminase [add]. 12 357 55.806 T 10-11-2016 IPR028893 Adenosine deaminase GO:0004000|GO:0009168 KEGG: 00230+3.5.4.4|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-74217 A4G23_RS17640 ae44e095ca34a5bd8ff47c7c71327d58 385 Pfam PF00962 Adenosine/AMP deaminase 17 354 1.4E-88 T 10-11-2016 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 A4G23_RS11150 b3b57f12f8b6e69c517874e457dbd111 325 PIRSF PIRSF037196 4 316 4.4E-107 T 10-11-2016 IPR017133 Pyoverdine chromophore biosynthesis protein PvcA A4G23_RS11150 b3b57f12f8b6e69c517874e457dbd111 325 Pfam PF05141 Pyoverdine/dityrosine biosynthesis protein 44 293 1.1E-72 T 10-11-2016 IPR007817 Pyoverdine biosynthesis A4G23_RS14795 de4bac29aaca9ace8c8d6f8c77ecdd3f 154 SUPERFAMILY SSF89095 3 152 1.15E-37 T 10-11-2016 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 A4G23_RS14795 de4bac29aaca9ace8c8d6f8c77ecdd3f 154 Gene3D G3DSA:1.10.10.410 94 153 2.5E-21 T 10-11-2016 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal A4G23_RS14795 de4bac29aaca9ace8c8d6f8c77ecdd3f 154 Pfam PF09424 Yqey-like protein 5 152 1.7E-47 T 10-11-2016 IPR019004 Uncharacterised domain YOR215C, mitochondrial A4G23_RS14795 de4bac29aaca9ace8c8d6f8c77ecdd3f 154 Gene3D G3DSA:1.10.1510.10 3 93 8.8E-27 T 10-11-2016 A4G23_RS27065 1c8585ce3b070f863ea30989546510c9 159 SUPERFAMILY SSF54001 41 149 2.31E-37 T 10-11-2016 A4G23_RS27065 1c8585ce3b070f863ea30989546510c9 159 Gene3D G3DSA:3.90.1720.10 39 149 5.1E-40 T 10-11-2016 IPR000064 Endopeptidase, NLPC/P60 domain A4G23_RS27065 1c8585ce3b070f863ea30989546510c9 159 Pfam PF00877 NlpC/P60 family 58 145 6.2E-26 T 10-11-2016 IPR000064 Endopeptidase, NLPC/P60 domain A4G23_RS20220 9fad9f05f0c81c2bebce1590c0cc74da 527 SUPERFAMILY SSF52096 16 267 4.98E-75 T 10-11-2016 IPR029045 ClpP/crotonase-like domain A4G23_RS20220 9fad9f05f0c81c2bebce1590c0cc74da 527 Pfam PF01039 Carboxyl transferase domain 40 524 1.4E-200 T 10-11-2016 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4G23_RS20220 9fad9f05f0c81c2bebce1590c0cc74da 527 Gene3D G3DSA:3.90.226.10 266 526 1.1E-103 T 10-11-2016 IPR029045 ClpP/crotonase-like domain A4G23_RS20220 9fad9f05f0c81c2bebce1590c0cc74da 527 Gene3D G3DSA:3.90.226.10 20 265 2.0E-76 T 10-11-2016 IPR029045 ClpP/crotonase-like domain A4G23_RS20220 9fad9f05f0c81c2bebce1590c0cc74da 527 SUPERFAMILY SSF52096 265 527 3.04E-91 T 10-11-2016 IPR029045 ClpP/crotonase-like domain A4G23_RS00900 5f82b308252b3b48223273b2151e4713 248 Pfam PF02361 Cobalt transport protein 11 213 1.9E-47 T 10-11-2016 IPR003339 ABC/ECF transporter, transmembrane component A4G23_RS00900 5f82b308252b3b48223273b2151e4713 248 TIGRFAM TIGR02454 ECF_T_CbiQ: cobalt ECF transporter T component CbiQ 16 207 3.3E-46 T 10-11-2016 IPR012809 Cobalt ECF transporter T component CbiQ GO:0005887|GO:0006824|GO:0043190 A4G23_RS02980 908f20e660b9dad1747da761b069afc5 301 SUPERFAMILY SSF53850 91 297 3.26E-32 T 10-11-2016 A4G23_RS02980 908f20e660b9dad1747da761b069afc5 301 Gene3D G3DSA:1.10.10.10 2 87 1.2E-25 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS02980 908f20e660b9dad1747da761b069afc5 301 Gene3D G3DSA:3.40.190.10 183 266 1.1E-20 T 10-11-2016 A4G23_RS02980 908f20e660b9dad1747da761b069afc5 301 SUPERFAMILY SSF46785 2 111 6.32E-23 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS02980 908f20e660b9dad1747da761b069afc5 301 Gene3D G3DSA:3.40.190.10 91 182 1.7E-15 T 10-11-2016 A4G23_RS02980 908f20e660b9dad1747da761b069afc5 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 2.0E-21 T 10-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4G23_RS02980 908f20e660b9dad1747da761b069afc5 301 Pfam PF03466 LysR substrate binding domain 89 295 2.4E-36 T 10-11-2016 IPR005119 LysR, substrate-binding A4G23_RS13355 49ad8cfb7cba7e398817c76e5afdba12 224 SUPERFAMILY SSF63817 64 211 1.83E-30 T 10-11-2016 IPR023365 Sortase domain A4G23_RS13355 49ad8cfb7cba7e398817c76e5afdba12 224 TIGRFAM TIGR01076 sortase_fam: sortase 71 209 4.1E-13 T 10-11-2016 IPR005754 Sortase family A4G23_RS13355 49ad8cfb7cba7e398817c76e5afdba12 224 Gene3D G3DSA:2.40.260.10 66 211 3.5E-25 T 10-11-2016 IPR023365 Sortase domain A4G23_RS13355 49ad8cfb7cba7e398817c76e5afdba12 224 Pfam PF04203 Sortase family 73 208 1.6E-24 T 10-11-2016 IPR005754 Sortase family A4G23_RS11470 89003434f491077c488c5257ec91db57 226 SMART SM00943 28 209 2.2E-33 T 10-11-2016 IPR015330 DNA primase/polymerase, bifunctional, N-terminal A4G23_RS11470 89003434f491077c488c5257ec91db57 226 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 28 201 3.9E-25 T 10-11-2016 IPR015330 DNA primase/polymerase, bifunctional, N-terminal A4G23_RS12780 009f4c529f1eccac115f8869094bcf90 740 Gene3D G3DSA:3.40.50.300 53 270 1.2E-69 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS12780 009f4c529f1eccac115f8869094bcf90 740 SUPERFAMILY SSF52540 133 417 1.21E-63 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS12780 009f4c529f1eccac115f8869094bcf90 740 Pfam PF00271 Helicase conserved C-terminal domain 298 396 8.5E-23 T 10-11-2016 IPR001650 Helicase, C-terminal A4G23_RS12780 009f4c529f1eccac115f8869094bcf90 740 Gene3D G3DSA:3.40.50.300 271 420 1.3E-42 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS12780 009f4c529f1eccac115f8869094bcf90 740 Pfam PF00270 DEAD/DEAH box helicase 86 253 1.8E-44 T 10-11-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A4G23_RS12780 009f4c529f1eccac115f8869094bcf90 740 SMART SM00487 81 281 6.5E-49 T 10-11-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4G23_RS12780 009f4c529f1eccac115f8869094bcf90 740 SMART SM00490 315 396 6.3E-29 T 10-11-2016 IPR001650 Helicase, C-terminal A4G23_RS23755 3e47c7102c1b4c4f527e24b471bce995 220 SUPERFAMILY SSF89155 15 176 3.01E-28 T 10-11-2016 IPR020945 DMSO/Nitrate reductase chaperone A4G23_RS23755 3e47c7102c1b4c4f527e24b471bce995 220 Gene3D G3DSA:1.10.3480.10 21 135 9.0E-10 T 10-11-2016 IPR020945 DMSO/Nitrate reductase chaperone A4G23_RS23755 3e47c7102c1b4c4f527e24b471bce995 220 TIGRFAM TIGR00684 narJ: nitrate reductase molybdenum cofactor assembly chaperone 23 170 5.0E-34 T 10-11-2016 IPR003765 Nitrate reductase chaperone, NarJ GO:0051082|GO:0051131 A4G23_RS23755 3e47c7102c1b4c4f527e24b471bce995 220 Pfam PF02613 Nitrate reductase delta subunit 55 167 3.8E-15 T 10-11-2016 IPR020945 DMSO/Nitrate reductase chaperone A4G23_RS01455 7a4e6086a4b0252c6cdab4c7cd467edf 128 SMART SM00418 27 105 4.7E-25 T 10-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4G23_RS01455 7a4e6086a4b0252c6cdab4c7cd467edf 128 SUPERFAMILY SSF46785 20 107 7.49E-24 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS01455 7a4e6086a4b0252c6cdab4c7cd467edf 128 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 61 76 1.4E-10 T 10-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4G23_RS01455 7a4e6086a4b0252c6cdab4c7cd467edf 128 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 29 44 1.4E-10 T 10-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4G23_RS01455 7a4e6086a4b0252c6cdab4c7cd467edf 128 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 76 91 1.4E-10 T 10-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4G23_RS01455 7a4e6086a4b0252c6cdab4c7cd467edf 128 Gene3D G3DSA:1.10.10.10 11 109 2.2E-27 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS01455 7a4e6086a4b0252c6cdab4c7cd467edf 128 Pfam PF01022 Bacterial regulatory protein, arsR family 35 79 1.7E-12 T 10-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4G23_RS23865 d7a04dac75059206a13e7b6d96348a53 149 SUPERFAMILY SSF55874 40 134 1.35E-6 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS23865 d7a04dac75059206a13e7b6d96348a53 149 Pfam PF13581 Histidine kinase-like ATPase domain 24 129 1.9E-10 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS23865 d7a04dac75059206a13e7b6d96348a53 149 Gene3D G3DSA:3.30.565.10 31 132 9.2E-4 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS26340 6972896975d45eb7cc1ecebde856d134 72 Gene3D G3DSA:3.90.820.10 11 68 8.5E-30 T 10-11-2016 A4G23_RS26340 6972896975d45eb7cc1ecebde856d134 72 Pfam PF03621 MbtH-like protein 3 51 2.5E-20 T 10-11-2016 IPR005153 MbtH-like protein A4G23_RS26340 6972896975d45eb7cc1ecebde856d134 72 SMART SM00923 8 53 2.3E-16 T 10-11-2016 IPR005153 MbtH-like protein A4G23_RS26340 6972896975d45eb7cc1ecebde856d134 72 SUPERFAMILY SSF160582 7 68 1.01E-25 T 10-11-2016 A4G23_RS18350 c0ccd4490752c60c476d8de1623e4869 325 Gene3D G3DSA:1.10.260.40 33 87 4.8E-9 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS18350 c0ccd4490752c60c476d8de1623e4869 325 SUPERFAMILY SSF47413 27 83 6.76E-8 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS18350 c0ccd4490752c60c476d8de1623e4869 325 Pfam PF13560 Helix-turn-helix domain 29 91 1.4E-12 T 10-11-2016 A4G23_RS18350 c0ccd4490752c60c476d8de1623e4869 325 SMART SM00530 32 89 6.3E-8 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS08075 ac24b8ec83b93c1b63c66488d4c7c6f8 206 Pfam PF01467 Cytidylyltransferase-like 17 178 3.0E-28 T 10-11-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A4G23_RS08075 ac24b8ec83b93c1b63c66488d4c7c6f8 206 SUPERFAMILY SSF52374 13 205 3.0E-53 T 10-11-2016 A4G23_RS08075 ac24b8ec83b93c1b63c66488d4c7c6f8 206 Gene3D G3DSA:3.40.50.620 13 204 8.3E-65 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS08075 ac24b8ec83b93c1b63c66488d4c7c6f8 206 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 13 204 28.775 T 10-11-2016 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: R-HSA-196807 A4G23_RS08075 ac24b8ec83b93c1b63c66488d4c7c6f8 206 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 17 203 9.0E-54 T 10-11-2016 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: R-HSA-196807 A4G23_RS08075 ac24b8ec83b93c1b63c66488d4c7c6f8 206 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 16 79 6.9E-11 T 10-11-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A4G23_RS14790 23f91bbc09e5b809648651afa48d02a4 308 SUPERFAMILY SSF56300 41 302 2.37E-25 T 10-11-2016 IPR029052 Metallo-dependent phosphatase-like A4G23_RS14790 23f91bbc09e5b809648651afa48d02a4 308 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 48 239 4.0E-7 T 10-11-2016 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 A4G23_RS14790 23f91bbc09e5b809648651afa48d02a4 308 Gene3D G3DSA:3.60.21.10 149 252 4.3E-12 T 10-11-2016 IPR029052 Metallo-dependent phosphatase-like A4G23_RS14790 23f91bbc09e5b809648651afa48d02a4 308 Gene3D G3DSA:3.60.21.10 46 116 4.3E-12 T 10-11-2016 IPR029052 Metallo-dependent phosphatase-like A4G23_RS08820 3a479b57f9569a446f53ee293a01de49 259 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 151 179 - T 10-11-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4G23_RS08820 3a479b57f9569a446f53ee293a01de49 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 1.3E-33 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS08820 3a479b57f9569a446f53ee293a01de49 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 1.3E-33 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS08820 3a479b57f9569a446f53ee293a01de49 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 1.3E-33 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS08820 3a479b57f9569a446f53ee293a01de49 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 1.3E-33 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS08820 3a479b57f9569a446f53ee293a01de49 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 1.3E-33 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS08820 3a479b57f9569a446f53ee293a01de49 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 102 1.3E-33 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS08820 3a479b57f9569a446f53ee293a01de49 259 Gene3D G3DSA:3.40.50.720 9 258 1.2E-82 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS08820 3a479b57f9569a446f53ee293a01de49 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 164 183 6.2E-6 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS08820 3a479b57f9569a446f53ee293a01de49 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 152 6.2E-6 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS08820 3a479b57f9569a446f53ee293a01de49 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 91 102 6.2E-6 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS08820 3a479b57f9569a446f53ee293a01de49 259 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 16 185 0.0033 T 10-11-2016 A4G23_RS08820 3a479b57f9569a446f53ee293a01de49 259 SUPERFAMILY SSF51735 15 258 1.45E-78 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS08820 3a479b57f9569a446f53ee293a01de49 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 24 257 7.7E-59 T 10-11-2016 A4G23_RS16790 22f7ca40250c308eabea9e0162377c91 615 Pfam PF13522 Glutamine amidotransferase domain 66 194 1.5E-22 T 10-11-2016 A4G23_RS16790 22f7ca40250c308eabea9e0162377c91 615 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 615 40.943 T 10-11-2016 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 A4G23_RS16790 22f7ca40250c308eabea9e0162377c91 615 Gene3D G3DSA:3.40.50.10490 445 615 1.6E-59 T 10-11-2016 A4G23_RS16790 22f7ca40250c308eabea9e0162377c91 615 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 615 9.4E-246 T 10-11-2016 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 A4G23_RS16790 22f7ca40250c308eabea9e0162377c91 615 SUPERFAMILY SSF56235 2 234 1.46E-67 T 10-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal A4G23_RS16790 22f7ca40250c308eabea9e0162377c91 615 Gene3D G3DSA:3.60.20.10 2 242 2.0E-75 T 10-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal A4G23_RS16790 22f7ca40250c308eabea9e0162377c91 615 Pfam PF01380 SIS domain 464 596 3.1E-22 T 10-11-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 A4G23_RS16790 22f7ca40250c308eabea9e0162377c91 615 Pfam PF01380 SIS domain 292 418 8.5E-35 T 10-11-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 A4G23_RS16790 22f7ca40250c308eabea9e0162377c91 615 SUPERFAMILY SSF53697 247 615 2.97E-108 T 10-11-2016 A4G23_RS16790 22f7ca40250c308eabea9e0162377c91 615 Gene3D G3DSA:3.40.50.10490 246 444 1.5E-74 T 10-11-2016 A4G23_RS14545 faf4c55e3dbb0529a47691fc8b41d410 308 SUPERFAMILY SSF53474 9 94 4.09E-38 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS14545 faf4c55e3dbb0529a47691fc8b41d410 308 SUPERFAMILY SSF53474 125 302 4.09E-38 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS14545 faf4c55e3dbb0529a47691fc8b41d410 308 Gene3D G3DSA:3.40.50.1820 12 303 1.4E-42 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS14545 faf4c55e3dbb0529a47691fc8b41d410 308 Pfam PF00326 Prolyl oligopeptidase family 110 175 7.2E-6 T 10-11-2016 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 A4G23_RS22870 ef003380f8285f673fe1dec70206edf0 403 ProSitePatterns PS01125 ROK family signature. 215 242 - T 10-11-2016 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A4G23_RS22870 ef003380f8285f673fe1dec70206edf0 403 SUPERFAMILY SSF53067 79 383 6.48E-63 T 10-11-2016 A4G23_RS22870 ef003380f8285f673fe1dec70206edf0 403 Pfam PF00480 ROK family 82 378 4.1E-62 T 10-11-2016 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A4G23_RS22870 ef003380f8285f673fe1dec70206edf0 403 Gene3D G3DSA:3.30.420.40 77 219 6.4E-45 T 10-11-2016 A4G23_RS22870 ef003380f8285f673fe1dec70206edf0 403 Gene3D G3DSA:3.30.420.40 220 361 2.1E-51 T 10-11-2016 A4G23_RS22870 ef003380f8285f673fe1dec70206edf0 403 Gene3D G3DSA:1.10.10.10 11 74 1.6E-14 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS22870 ef003380f8285f673fe1dec70206edf0 403 SUPERFAMILY SSF46785 11 71 1.26E-11 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS22870 ef003380f8285f673fe1dec70206edf0 403 Pfam PF12802 MarR family 17 68 1.2E-8 T 10-11-2016 A4G23_RS16035 0ec36896e67891bb865ca59a2bea7afb 289 PIRSF PIRSF000103 2 289 3.1E-38 T 10-11-2016 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 A4G23_RS16035 0ec36896e67891bb865ca59a2bea7afb 289 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 5 154 1.6E-22 T 10-11-2016 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 A4G23_RS16035 0ec36896e67891bb865ca59a2bea7afb 289 SUPERFAMILY SSF51735 5 154 5.4E-33 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS16035 0ec36896e67891bb865ca59a2bea7afb 289 Gene3D G3DSA:1.10.1040.10 186 286 4.2E-4 T 10-11-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A4G23_RS16035 0ec36896e67891bb865ca59a2bea7afb 289 Gene3D G3DSA:3.40.50.720 1 155 9.0E-35 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS00255 1f2e1bb40e7e620bb26c156ae41ab7df 760 SUPERFAMILY SSF81606 551 748 4.97E-11 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS00255 1f2e1bb40e7e620bb26c156ae41ab7df 760 Gene3D G3DSA:3.30.450.40 13 149 4.8E-6 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS00255 1f2e1bb40e7e620bb26c156ae41ab7df 760 SUPERFAMILY SSF55785 187 271 4.89E-7 T 10-11-2016 IPR000014 PAS domain A4G23_RS00255 1f2e1bb40e7e620bb26c156ae41ab7df 760 SMART SM00331 534 749 1.2E-45 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS00255 1f2e1bb40e7e620bb26c156ae41ab7df 760 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 564 749 7.6E-53 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS00255 1f2e1bb40e7e620bb26c156ae41ab7df 760 Pfam PF08448 PAS fold 189 275 1.9E-8 T 10-11-2016 IPR013656 PAS fold-4 A4G23_RS00255 1f2e1bb40e7e620bb26c156ae41ab7df 760 Pfam PF13185 GAF domain 370 507 4.7E-13 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS00255 1f2e1bb40e7e620bb26c156ae41ab7df 760 Gene3D G3DSA:3.30.450.20 186 278 7.7E-9 T 10-11-2016 A4G23_RS00255 1f2e1bb40e7e620bb26c156ae41ab7df 760 SUPERFAMILY SSF55781 13 148 1.13E-8 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS00255 1f2e1bb40e7e620bb26c156ae41ab7df 760 SUPERFAMILY SSF55781 372 519 2.4E-17 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS00255 1f2e1bb40e7e620bb26c156ae41ab7df 760 Gene3D G3DSA:3.30.450.40 350 518 3.1E-16 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS00255 1f2e1bb40e7e620bb26c156ae41ab7df 760 SMART SM00065 369 516 0.0028 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS06985 4b5beb3fa5d70b941d074848a010f343 285 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 41 283 2.3E-92 T 10-11-2016 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 A4G23_RS06985 4b5beb3fa5d70b941d074848a010f343 285 Hamap MF_01974 Methionine aminopeptidase [map]. 39 285 40.22 T 10-11-2016 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 A4G23_RS06985 4b5beb3fa5d70b941d074848a010f343 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 104 117 8.6E-21 T 10-11-2016 IPR001714 Peptidase M24, methionine aminopeptidase A4G23_RS06985 4b5beb3fa5d70b941d074848a010f343 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 126 142 8.6E-21 T 10-11-2016 IPR001714 Peptidase M24, methionine aminopeptidase A4G23_RS06985 4b5beb3fa5d70b941d074848a010f343 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 227 239 8.6E-21 T 10-11-2016 IPR001714 Peptidase M24, methionine aminopeptidase A4G23_RS06985 4b5beb3fa5d70b941d074848a010f343 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 196 208 8.6E-21 T 10-11-2016 IPR001714 Peptidase M24, methionine aminopeptidase A4G23_RS06985 4b5beb3fa5d70b941d074848a010f343 285 Pfam PF00557 Metallopeptidase family M24 48 276 9.3E-54 T 10-11-2016 IPR000994 Peptidase M24, structural domain A4G23_RS06985 4b5beb3fa5d70b941d074848a010f343 285 SUPERFAMILY SSF55920 5 284 5.63E-86 T 10-11-2016 IPR000994 Peptidase M24, structural domain A4G23_RS06985 4b5beb3fa5d70b941d074848a010f343 285 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 202 220 - T 10-11-2016 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 A4G23_RS06985 4b5beb3fa5d70b941d074848a010f343 285 Gene3D G3DSA:3.90.230.10 41 284 4.4E-96 T 10-11-2016 IPR000994 Peptidase M24, structural domain A4G23_RS24215 e7c8543a2250a7644c4e58c50bde4293 189 Gene3D G3DSA:3.40.50.360 2 183 9.1E-48 T 10-11-2016 IPR029039 Flavoprotein-like domain A4G23_RS24215 e7c8543a2250a7644c4e58c50bde4293 189 Pfam PF03358 NADPH-dependent FMN reductase 4 149 3.1E-36 T 10-11-2016 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 A4G23_RS24215 e7c8543a2250a7644c4e58c50bde4293 189 SUPERFAMILY SSF52218 4 176 8.06E-43 T 10-11-2016 IPR029039 Flavoprotein-like domain A4G23_RS25445 5924c7f74ef0d58e79722137511f648b 207 Pfam PF04343 Protein of unknown function, DUF488 16 147 2.2E-22 T 10-11-2016 IPR007438 Protein of unknown function DUF488 A4G23_RS25445 5924c7f74ef0d58e79722137511f648b 207 PIRSF PIRSF024492 1 194 1.4E-41 T 10-11-2016 IPR014519 Uncharacterised conserved protein UCP024492 A4G23_RS10595 08119e679fc1df19386e4ef357aeff62 165 SMART SM00347 43 146 1.5E-22 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS10595 08119e679fc1df19386e4ef357aeff62 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 106 122 7.7E-11 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS10595 08119e679fc1df19386e4ef357aeff62 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 102 7.7E-11 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS10595 08119e679fc1df19386e4ef357aeff62 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 86 7.7E-11 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS10595 08119e679fc1df19386e4ef357aeff62 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 136 156 7.7E-11 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS10595 08119e679fc1df19386e4ef357aeff62 165 SUPERFAMILY SSF46785 11 160 1.21E-33 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS10595 08119e679fc1df19386e4ef357aeff62 165 Gene3D G3DSA:1.10.10.10 9 161 1.8E-37 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS10595 08119e679fc1df19386e4ef357aeff62 165 Pfam PF01047 MarR family 54 111 7.3E-13 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS10595 08119e679fc1df19386e4ef357aeff62 165 ProSitePatterns PS01117 MarR-type HTH domain signature. 85 119 - T 10-11-2016 IPR023187 Transcriptional regulator MarR-type, conserved site A4G23_RS06500 fc18c4ded02eb80dbb45a8a0da4adae4 341 Pfam PF00877 NlpC/P60 family 242 330 4.3E-22 T 10-11-2016 IPR000064 Endopeptidase, NLPC/P60 domain A4G23_RS06500 fc18c4ded02eb80dbb45a8a0da4adae4 341 SUPERFAMILY SSF54001 224 340 8.83E-36 T 10-11-2016 A4G23_RS06500 fc18c4ded02eb80dbb45a8a0da4adae4 341 Gene3D G3DSA:3.90.1720.10 223 331 2.5E-39 T 10-11-2016 IPR000064 Endopeptidase, NLPC/P60 domain A4G23_RS25110 ae90dcde99c1f22ca00c17d75b40ffc1 534 TIGRFAM TIGR02734 crtI_fam: phytoene desaturase 11 497 6.2E-177 T 10-11-2016 IPR014105 Carotenoid/retinoid oxidoreductase GO:0016117|GO:0055114 A4G23_RS25110 ae90dcde99c1f22ca00c17d75b40ffc1 534 ProSitePatterns PS00982 Bacterial-type phytoene dehydrogenase signature. 462 482 - T 10-11-2016 IPR008150 Phytoene dehydrogenase, bacterial-type, conserved site A4G23_RS25110 ae90dcde99c1f22ca00c17d75b40ffc1 534 Gene3D G3DSA:3.50.50.60 446 497 1.9E-37 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS25110 ae90dcde99c1f22ca00c17d75b40ffc1 534 Gene3D G3DSA:3.50.50.60 10 64 1.9E-37 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS25110 ae90dcde99c1f22ca00c17d75b40ffc1 534 Gene3D G3DSA:3.50.50.60 125 139 1.9E-37 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS25110 ae90dcde99c1f22ca00c17d75b40ffc1 534 Gene3D G3DSA:3.50.50.60 218 301 1.9E-37 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS25110 ae90dcde99c1f22ca00c17d75b40ffc1 534 Pfam PF01593 Flavin containing amine oxidoreductase 18 490 2.6E-56 T 10-11-2016 IPR002937 Amine oxidase GO:0016491|GO:0055114 A4G23_RS25110 ae90dcde99c1f22ca00c17d75b40ffc1 534 SUPERFAMILY SSF51905 10 319 9.19E-65 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS25110 ae90dcde99c1f22ca00c17d75b40ffc1 534 SUPERFAMILY SSF51905 452 490 9.19E-65 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS19730 6dc8a654f06af5685c07c5b0887305b4 169 Pfam PF01047 MarR family 62 113 9.6E-12 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS19730 6dc8a654f06af5685c07c5b0887305b4 169 SMART SM00347 48 149 4.8E-22 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS19730 6dc8a654f06af5685c07c5b0887305b4 169 Gene3D G3DSA:1.10.10.10 28 159 6.6E-31 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS19730 6dc8a654f06af5685c07c5b0887305b4 169 ProSitePatterns PS01117 MarR-type HTH domain signature. 89 123 - T 10-11-2016 IPR023187 Transcriptional regulator MarR-type, conserved site A4G23_RS19730 6dc8a654f06af5685c07c5b0887305b4 169 PRINTS PR00598 Bacterial regulatory protein MarR family signature 91 106 8.3E-5 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS19730 6dc8a654f06af5685c07c5b0887305b4 169 PRINTS PR00598 Bacterial regulatory protein MarR family signature 110 126 8.3E-5 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS19730 6dc8a654f06af5685c07c5b0887305b4 169 PRINTS PR00598 Bacterial regulatory protein MarR family signature 74 90 8.3E-5 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS19730 6dc8a654f06af5685c07c5b0887305b4 169 SUPERFAMILY SSF46785 26 159 6.45E-27 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS06450 becdc71f1367b1600342ab3846e31c96 313 Gene3D G3DSA:3.30.420.40 1 134 3.1E-48 T 10-11-2016 A4G23_RS06450 becdc71f1367b1600342ab3846e31c96 313 Pfam PF00480 ROK family 4 312 9.5E-104 T 10-11-2016 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A4G23_RS06450 becdc71f1367b1600342ab3846e31c96 313 Gene3D G3DSA:3.30.420.40 135 292 2.5E-51 T 10-11-2016 A4G23_RS06450 becdc71f1367b1600342ab3846e31c96 313 ProSitePatterns PS01125 ROK family signature. 130 157 - T 10-11-2016 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A4G23_RS06450 becdc71f1367b1600342ab3846e31c96 313 TIGRFAM TIGR00744 ROK_glcA_fam: ROK family protein (putative glucokinase) 5 311 1.6E-135 T 10-11-2016 IPR004654 Glucokinase ROK GO:0004340|GO:0005737|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 A4G23_RS06450 becdc71f1367b1600342ab3846e31c96 313 SUPERFAMILY SSF53067 2 312 7.78E-71 T 10-11-2016 A4G23_RS13255 bb80c1076751ad3d3b2aba8d18b95253 509 Gene3D G3DSA:3.40.50.720 18 202 8.2E-56 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS13255 bb80c1076751ad3d3b2aba8d18b95253 509 SUPERFAMILY SSF48179 200 315 8.5E-28 T 10-11-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A4G23_RS13255 bb80c1076751ad3d3b2aba8d18b95253 509 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 201 298 5.7E-28 T 10-11-2016 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 A4G23_RS13255 bb80c1076751ad3d3b2aba8d18b95253 509 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 426 500 5.7E-14 T 10-11-2016 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 A4G23_RS13255 bb80c1076751ad3d3b2aba8d18b95253 509 SUPERFAMILY SSF48179 425 505 8.16E-13 T 10-11-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A4G23_RS13255 bb80c1076751ad3d3b2aba8d18b95253 509 SUPERFAMILY SSF51735 19 200 1.89E-54 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS13255 bb80c1076751ad3d3b2aba8d18b95253 509 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 20 198 5.8E-60 T 10-11-2016 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 A4G23_RS13255 bb80c1076751ad3d3b2aba8d18b95253 509 Gene3D G3DSA:1.10.1040.10 426 501 2.9E-14 T 10-11-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A4G23_RS13255 bb80c1076751ad3d3b2aba8d18b95253 509 Gene3D G3DSA:1.10.1040.10 203 299 5.5E-27 T 10-11-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A4G23_RS05645 d07ada753e148d692311261de9a35717 510 PIRSF PIRSF026631 29 498 1.8E-61 T 10-11-2016 IPR014529 Uncharacterised conserved protein UCP026631 A4G23_RS05645 d07ada753e148d692311261de9a35717 510 Pfam PF03703 Bacterial PH domain 79 157 2.6E-8 T 10-11-2016 IPR005182 Domain of unknown function DUF304 A4G23_RS05645 d07ada753e148d692311261de9a35717 510 Pfam PF03703 Bacterial PH domain 419 478 9.3E-6 T 10-11-2016 IPR005182 Domain of unknown function DUF304 A4G23_RS08995 fb8bf74de0b8830656d636606cf9527a 480 SUPERFAMILY SSF53383 14 470 9.63E-119 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS08995 fb8bf74de0b8830656d636606cf9527a 480 Gene3D G3DSA:3.40.640.10 90 355 4.6E-92 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS08995 fb8bf74de0b8830656d636606cf9527a 480 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 341 356 4.4E-5 T 10-11-2016 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 A4G23_RS08995 fb8bf74de0b8830656d636606cf9527a 480 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 384 403 4.4E-5 T 10-11-2016 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 A4G23_RS08995 fb8bf74de0b8830656d636606cf9527a 480 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 80 99 4.4E-5 T 10-11-2016 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 A4G23_RS08995 fb8bf74de0b8830656d636606cf9527a 480 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 78 402 3.3E-57 T 10-11-2016 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 A4G23_RS08995 fb8bf74de0b8830656d636606cf9527a 480 Gene3D G3DSA:1.20.1650.10 4 79 1.4E-24 T 10-11-2016 A4G23_RS08995 fb8bf74de0b8830656d636606cf9527a 480 Gene3D G3DSA:3.90.1150.10 356 471 1.3E-41 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS22010 459f235bb1dca6acda8051f166bb37a1 304 Gene3D G3DSA:1.10.3720.10 31 290 4.4E-57 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS22010 459f235bb1dca6acda8051f166bb37a1 304 SUPERFAMILY SSF161098 37 304 7.98E-64 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS22010 459f235bb1dca6acda8051f166bb37a1 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 120 289 3.9E-17 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS03055 6ea405214da44b147fe0254b97b01fb2 212 SMART SM00422 53 125 9.4E-17 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS03055 6ea405214da44b147fe0254b97b01fb2 212 Pfam PF13411 MerR HTH family regulatory protein 57 123 9.7E-13 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS03055 6ea405214da44b147fe0254b97b01fb2 212 Gene3D G3DSA:1.10.1660.10 59 135 7.7E-13 T 10-11-2016 A4G23_RS03055 6ea405214da44b147fe0254b97b01fb2 212 SUPERFAMILY SSF46955 57 141 6.87E-14 T 10-11-2016 IPR009061 Putative DNA-binding domain A4G23_RS01295 3eae7e766dbeeca1f86cfff7c62bb652 136 SUPERFAMILY SSF103196 4 129 6.98E-30 T 10-11-2016 A4G23_RS01295 3eae7e766dbeeca1f86cfff7c62bb652 136 Gene3D G3DSA:3.30.450.30 4 127 1.8E-26 T 10-11-2016 A4G23_RS01295 3eae7e766dbeeca1f86cfff7c62bb652 136 Pfam PF03259 Roadblock/LC7 domain 8 100 1.2E-24 T 10-11-2016 IPR004942 Roadblock/LAMTOR2 domain A4G23_RS01295 3eae7e766dbeeca1f86cfff7c62bb652 136 SMART SM00960 9 100 4.4E-27 T 10-11-2016 IPR004942 Roadblock/LAMTOR2 domain A4G23_RS00855 961b7e3604d47f70c9c3fb9337d10f4c 494 Gene3D G3DSA:3.50.50.60 2 129 2.5E-17 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS00855 961b7e3604d47f70c9c3fb9337d10f4c 494 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 324 3.2E-21 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS00855 961b7e3604d47f70c9c3fb9337d10f4c 494 Pfam PF04324 BFD-like [2Fe-2S] binding domain 393 441 5.1E-11 T 10-11-2016 IPR007419 BFD-like [2Fe-2S]-binding domain A4G23_RS00855 961b7e3604d47f70c9c3fb9337d10f4c 494 PIRSF PIRSF037495 1 474 9.6E-145 T 10-11-2016 IPR017224 Opine oxidase, subunit A/hydrogen cyanide synthase, subunit B GO:0016491|GO:0055114 A4G23_RS00855 961b7e3604d47f70c9c3fb9337d10f4c 494 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 124 133 3.1E-12 T 10-11-2016 A4G23_RS00855 961b7e3604d47f70c9c3fb9337d10f4c 494 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 3.1E-12 T 10-11-2016 A4G23_RS00855 961b7e3604d47f70c9c3fb9337d10f4c 494 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 317 324 3.1E-12 T 10-11-2016 A4G23_RS00855 961b7e3604d47f70c9c3fb9337d10f4c 494 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 165 190 3.1E-12 T 10-11-2016 A4G23_RS00855 961b7e3604d47f70c9c3fb9337d10f4c 494 SUPERFAMILY SSF51905 5 368 2.76E-35 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS00855 961b7e3604d47f70c9c3fb9337d10f4c 494 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 302 324 1.4E-19 T 10-11-2016 A4G23_RS00855 961b7e3604d47f70c9c3fb9337d10f4c 494 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 121 139 1.4E-19 T 10-11-2016 A4G23_RS00855 961b7e3604d47f70c9c3fb9337d10f4c 494 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.4E-19 T 10-11-2016 A4G23_RS00855 961b7e3604d47f70c9c3fb9337d10f4c 494 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 165 183 1.4E-19 T 10-11-2016 A4G23_RS00855 961b7e3604d47f70c9c3fb9337d10f4c 494 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 271 287 1.4E-19 T 10-11-2016 A4G23_RS00855 961b7e3604d47f70c9c3fb9337d10f4c 494 Gene3D G3DSA:3.50.50.60 130 344 3.7E-25 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS21855 b1029d5bc391bb6620bbb7227be1ca93 118 SUPERFAMILY SSF52540 7 87 2.3E-14 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS21855 b1029d5bc391bb6620bbb7227be1ca93 118 Pfam PF13361 UvrD-like helicase C-terminal domain 7 77 4.4E-13 T 10-11-2016 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 A4G23_RS21855 b1029d5bc391bb6620bbb7227be1ca93 118 Gene3D G3DSA:3.40.50.300 6 90 5.8E-19 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS09760 3a6f9523ac9f36633c0a2ba6c1951c10 1206 SMART SM00240 120 171 2.9E-13 T 10-11-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 A4G23_RS09760 3a6f9523ac9f36633c0a2ba6c1951c10 1206 SUPERFAMILY SSF52540 939 950 3.22E-8 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS09760 3a6f9523ac9f36633c0a2ba6c1951c10 1206 SUPERFAMILY SSF52540 1027 1101 3.22E-8 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS09760 3a6f9523ac9f36633c0a2ba6c1951c10 1206 SUPERFAMILY SSF52540 855 900 3.22E-8 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS09760 3a6f9523ac9f36633c0a2ba6c1951c10 1206 Gene3D G3DSA:3.40.50.300 1023 1081 6.4E-7 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS09760 3a6f9523ac9f36633c0a2ba6c1951c10 1206 Gene3D G3DSA:3.40.50.300 859 937 6.4E-7 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS09760 3a6f9523ac9f36633c0a2ba6c1951c10 1206 Pfam PF16697 Inner membrane component of T3SS, cytoplasmic domain 104 194 4.0E-15 T 10-11-2016 IPR032030 YscD, cytoplasmic domain A4G23_RS09760 3a6f9523ac9f36633c0a2ba6c1951c10 1206 Gene3D G3DSA:2.60.200.20 96 194 9.5E-23 T 10-11-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 A4G23_RS09760 3a6f9523ac9f36633c0a2ba6c1951c10 1206 SUPERFAMILY SSF49879 87 193 3.44E-25 T 10-11-2016 IPR008984 SMAD/FHA domain GO:0005515 A4G23_RS09760 3a6f9523ac9f36633c0a2ba6c1951c10 1206 Pfam PF01580 FtsK/SpoIIIE family 851 952 1.8E-11 T 10-11-2016 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 A4G23_RS09760 3a6f9523ac9f36633c0a2ba6c1951c10 1206 SMART SM00382 859 1102 2.2E-4 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS00055 23299e947e8761f1dca5b27cdf8b43b7 282 Gene3D G3DSA:1.10.10.10 211 248 7.0E-5 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS06250 72173b180cc9ffffcbdf8985d2e35d2a 488 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 17 481 3.1E-119 T 10-11-2016 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4G23_RS06250 72173b180cc9ffffcbdf8985d2e35d2a 488 Gene3D G3DSA:3.90.190.20 340 480 3.6E-45 T 10-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4G23_RS06250 72173b180cc9ffffcbdf8985d2e35d2a 488 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 129 152 - T 10-11-2016 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 A4G23_RS06250 72173b180cc9ffffcbdf8985d2e35d2a 488 SUPERFAMILY SSF53623 125 336 2.88E-47 T 10-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4G23_RS06250 72173b180cc9ffffcbdf8985d2e35d2a 488 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 16 483 33.899 T 10-11-2016 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4G23_RS06250 72173b180cc9ffffcbdf8985d2e35d2a 488 SUPERFAMILY SSF53244 340 483 1.51E-37 T 10-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4G23_RS06250 72173b180cc9ffffcbdf8985d2e35d2a 488 Gene3D G3DSA:3.40.1190.10 109 337 7.6E-66 T 10-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4G23_RS06250 72173b180cc9ffffcbdf8985d2e35d2a 488 Gene3D G3DSA:3.40.50.720 12 108 1.6E-20 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS06250 72173b180cc9ffffcbdf8985d2e35d2a 488 Pfam PF08245 Mur ligase middle domain 131 319 1.8E-25 T 10-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4G23_RS06250 72173b180cc9ffffcbdf8985d2e35d2a 488 Pfam PF02875 Mur ligase family, glutamate ligase domain 341 406 7.3E-7 T 10-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4G23_RS06250 72173b180cc9ffffcbdf8985d2e35d2a 488 SUPERFAMILY SSF51984 12 109 6.8E-17 T 10-11-2016 A4G23_RS07625 d8031984b47521f6f0a08b9ce03efa14 480 Gene3D G3DSA:1.20.1250.20 66 252 1.4E-25 T 10-11-2016 A4G23_RS07625 d8031984b47521f6f0a08b9ce03efa14 480 Gene3D G3DSA:1.20.1250.20 268 451 2.1E-17 T 10-11-2016 A4G23_RS07625 d8031984b47521f6f0a08b9ce03efa14 480 SUPERFAMILY SSF103473 53 454 1.7E-52 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS07625 d8031984b47521f6f0a08b9ce03efa14 480 Pfam PF07690 Major Facilitator Superfamily 69 413 6.7E-35 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS01330 7d0626fd31a2b8bc3f08db61db4353dc 523 Pfam PF07690 Major Facilitator Superfamily 29 420 4.4E-55 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS01330 7d0626fd31a2b8bc3f08db61db4353dc 523 SUPERFAMILY SSF103473 258 430 2.88E-68 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS01330 7d0626fd31a2b8bc3f08db61db4353dc 523 SUPERFAMILY SSF103473 472 499 2.88E-68 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS01330 7d0626fd31a2b8bc3f08db61db4353dc 523 SUPERFAMILY SSF103473 22 208 2.88E-68 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS01330 7d0626fd31a2b8bc3f08db61db4353dc 523 Gene3D G3DSA:1.20.1250.20 473 501 2.3E-16 T 10-11-2016 A4G23_RS01330 7d0626fd31a2b8bc3f08db61db4353dc 523 Gene3D G3DSA:1.20.1250.20 281 431 2.3E-16 T 10-11-2016 A4G23_RS01330 7d0626fd31a2b8bc3f08db61db4353dc 523 PRINTS PR01036 Tetracycline resistance protein TetB signature 87 109 3.2E-5 T 10-11-2016 A4G23_RS01330 7d0626fd31a2b8bc3f08db61db4353dc 523 PRINTS PR01036 Tetracycline resistance protein TetB signature 27 51 3.2E-5 T 10-11-2016 A4G23_RS01330 7d0626fd31a2b8bc3f08db61db4353dc 523 PRINTS PR01036 Tetracycline resistance protein TetB signature 149 173 3.2E-5 T 10-11-2016 A4G23_RS01330 7d0626fd31a2b8bc3f08db61db4353dc 523 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 25 428 6.4E-69 T 10-11-2016 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 A4G23_RS01330 7d0626fd31a2b8bc3f08db61db4353dc 523 Gene3D G3DSA:1.20.1250.20 25 205 4.0E-29 T 10-11-2016 A4G23_RS09260 a7f6a0a13fa31cec2fdff300bf43ec48 216 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 109 9.4E-29 T 10-11-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 A4G23_RS09260 a7f6a0a13fa31cec2fdff300bf43ec48 216 Gene3D G3DSA:1.10.3720.10 13 214 2.0E-40 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS09260 a7f6a0a13fa31cec2fdff300bf43ec48 216 TIGRFAM TIGR03003 ectoine_ehuD: ectoine/hydroxyectoine ABC transporter, permease protein EhuD 3 214 1.5E-79 T 10-11-2016 IPR014341 Ectoine/hydroxyectoine ABC transporter, permease protein EhuD A4G23_RS09260 a7f6a0a13fa31cec2fdff300bf43ec48 216 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 36 214 5.9E-19 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS09260 a7f6a0a13fa31cec2fdff300bf43ec48 216 SUPERFAMILY SSF161098 13 200 3.53E-37 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS24485 dc3904f95e6e311f100c52153e82b206 500 PIRSF PIRSF006060 35 478 4.1E-67 T 10-11-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A4G23_RS24485 dc3904f95e6e311f100c52153e82b206 500 Pfam PF13520 Amino acid permease 48 454 2.1E-52 T 10-11-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A4G23_RS03235 71f0dcc22bf95e7cdf40b9ca29496d84 530 Gene3D G3DSA:3.40.50.300 264 478 7.7E-16 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS03235 71f0dcc22bf95e7cdf40b9ca29496d84 530 SUPERFAMILY SSF52540 244 448 2.96E-13 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS13695 97474acc07b29199d96b1d95730a5e32 424 Pfam PF00149 Calcineurin-like phosphoesterase 155 371 3.7E-10 T 10-11-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 A4G23_RS13695 97474acc07b29199d96b1d95730a5e32 424 PRINTS PR00114 Serine/threonine phosphatase family signature 155 182 9.0E-6 T 10-11-2016 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04660+3.1.3.16 A4G23_RS13695 97474acc07b29199d96b1d95730a5e32 424 PRINTS PR00114 Serine/threonine phosphatase family signature 192 219 9.0E-6 T 10-11-2016 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04660+3.1.3.16 A4G23_RS13695 97474acc07b29199d96b1d95730a5e32 424 Gene3D G3DSA:3.60.21.10 145 415 6.1E-34 T 10-11-2016 IPR029052 Metallo-dependent phosphatase-like A4G23_RS13695 97474acc07b29199d96b1d95730a5e32 424 SUPERFAMILY SSF56300 153 411 1.99E-33 T 10-11-2016 IPR029052 Metallo-dependent phosphatase-like A4G23_RS01610 26a90a53d4327e20787ca98144eed43b 296 Gene3D G3DSA:1.10.1660.10 19 123 2.8E-14 T 10-11-2016 A4G23_RS01610 26a90a53d4327e20787ca98144eed43b 296 Gene3D G3DSA:1.10.1660.10 187 293 1.3E-20 T 10-11-2016 A4G23_RS01610 26a90a53d4327e20787ca98144eed43b 296 Pfam PF00376 MerR family regulatory protein 19 53 1.2E-11 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS01610 26a90a53d4327e20787ca98144eed43b 296 SUPERFAMILY SSF46955 187 293 3.19E-17 T 10-11-2016 IPR009061 Putative DNA-binding domain A4G23_RS01610 26a90a53d4327e20787ca98144eed43b 296 SUPERFAMILY SSF46955 19 124 1.65E-11 T 10-11-2016 IPR009061 Putative DNA-binding domain A4G23_RS01610 26a90a53d4327e20787ca98144eed43b 296 Pfam PF13411 MerR HTH family regulatory protein 187 252 4.4E-15 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS01610 26a90a53d4327e20787ca98144eed43b 296 SMART SM00422 15 83 0.0059 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS01610 26a90a53d4327e20787ca98144eed43b 296 SMART SM00422 185 254 1.3E-9 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS05810 231e7aa4d021c128b5fc1467eccb3200 989 SUPERFAMILY SSF52540 515 733 1.52E-51 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05810 231e7aa4d021c128b5fc1467eccb3200 989 Gene3D G3DSA:3.40.50.300 521 685 2.6E-19 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05810 231e7aa4d021c128b5fc1467eccb3200 989 Gene3D G3DSA:3.40.50.300 815 964 1.5E-22 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05810 231e7aa4d021c128b5fc1467eccb3200 989 Pfam PF00176 SNF2 family N-terminal domain 545 801 8.4E-48 T 10-11-2016 IPR000330 SNF2-related, N-terminal domain GO:0005524 A4G23_RS05810 231e7aa4d021c128b5fc1467eccb3200 989 SMART SM00487 522 699 1.9E-26 T 10-11-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4G23_RS05810 231e7aa4d021c128b5fc1467eccb3200 989 SMART SM00490 847 929 1.1E-22 T 10-11-2016 IPR001650 Helicase, C-terminal A4G23_RS05810 231e7aa4d021c128b5fc1467eccb3200 989 Pfam PF00271 Helicase conserved C-terminal domain 819 929 9.9E-17 T 10-11-2016 IPR001650 Helicase, C-terminal A4G23_RS05810 231e7aa4d021c128b5fc1467eccb3200 989 SUPERFAMILY SSF52540 741 985 4.03E-66 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05810 231e7aa4d021c128b5fc1467eccb3200 989 Pfam PF12419 SNF2 Helicase protein 354 483 2.7E-34 T 10-11-2016 IPR022138 Helicase SWF/SNF-related A4G23_RS26730 ed426d8495349cd0209b629d64f21087 172 PRINTS PR01100 Shikimate kinase family signature 59 67 7.7E-12 T 10-11-2016 A4G23_RS26730 ed426d8495349cd0209b629d64f21087 172 PRINTS PR01100 Shikimate kinase family signature 77 86 7.7E-12 T 10-11-2016 A4G23_RS26730 ed426d8495349cd0209b629d64f21087 172 PRINTS PR01100 Shikimate kinase family signature 7 22 7.7E-12 T 10-11-2016 A4G23_RS26730 ed426d8495349cd0209b629d64f21087 172 PRINTS PR01100 Shikimate kinase family signature 97 114 7.7E-12 T 10-11-2016 A4G23_RS26730 ed426d8495349cd0209b629d64f21087 172 ProSitePatterns PS01128 Shikimate kinase signature. 60 85 - T 10-11-2016 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 A4G23_RS26730 ed426d8495349cd0209b629d64f21087 172 Hamap MF_00109 Shikimate kinase [aroK]. 4 168 24.91 T 10-11-2016 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 A4G23_RS26730 ed426d8495349cd0209b629d64f21087 172 SUPERFAMILY SSF52540 4 167 1.55E-24 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS26730 ed426d8495349cd0209b629d64f21087 172 Gene3D G3DSA:3.40.50.300 5 168 1.8E-46 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS26730 ed426d8495349cd0209b629d64f21087 172 Pfam PF01202 Shikimate kinase 14 166 1.7E-36 T 10-11-2016 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 A4G23_RS00015 e7b565bc9871a08612a2eb8c34311a75 750 SUPERFAMILY SSF53098 360 484 3.19E-11 T 10-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 A4G23_RS00015 e7b565bc9871a08612a2eb8c34311a75 750 Pfam PF00665 Integrase core domain 277 412 1.2E-8 T 10-11-2016 IPR001584 Integrase, catalytic core GO:0015074 A4G23_RS00015 e7b565bc9871a08612a2eb8c34311a75 750 Gene3D G3DSA:3.30.420.10 256 314 1.4E-19 T 10-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 A4G23_RS00015 e7b565bc9871a08612a2eb8c34311a75 750 Gene3D G3DSA:3.30.420.10 352 465 1.4E-19 T 10-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 A4G23_RS19560 f70b9e81bb2bcf320c5f3d13468e10bb 271 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 111 269 2.0E-22 T 10-11-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 A4G23_RS19560 f70b9e81bb2bcf320c5f3d13468e10bb 271 Pfam PF00213 ATP synthase delta (OSCP) subunit 108 268 3.0E-33 T 10-11-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 A4G23_RS19560 f70b9e81bb2bcf320c5f3d13468e10bb 271 SUPERFAMILY SSF47928 108 198 3.53E-5 T 10-11-2016 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210 A4G23_RS19560 f70b9e81bb2bcf320c5f3d13468e10bb 271 Hamap MF_01416 ATP synthase subunit delta [atpD]. 87 271 15.883 T 10-11-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 A4G23_RS19560 f70b9e81bb2bcf320c5f3d13468e10bb 271 PRINTS PR00125 ATP synthase delta subunit signature 229 244 2.0E-8 T 10-11-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 A4G23_RS19560 f70b9e81bb2bcf320c5f3d13468e10bb 271 PRINTS PR00125 ATP synthase delta subunit signature 244 262 2.0E-8 T 10-11-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 A4G23_RS19560 f70b9e81bb2bcf320c5f3d13468e10bb 271 Gene3D G3DSA:1.10.520.20 108 197 2.7E-5 T 10-11-2016 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210 A4G23_RS10055 d649c50704e74fda71997d704eff6230 453 Gene3D G3DSA:3.30.300.30 348 451 8.0E-28 T 10-11-2016 A4G23_RS10055 d649c50704e74fda71997d704eff6230 453 PRINTS PR00154 AMP-binding signature 85 96 3.8E-5 T 10-11-2016 IPR020459 AMP-binding A4G23_RS10055 d649c50704e74fda71997d704eff6230 453 PRINTS PR00154 AMP-binding signature 97 105 3.8E-5 T 10-11-2016 IPR020459 AMP-binding A4G23_RS10055 d649c50704e74fda71997d704eff6230 453 Gene3D G3DSA:3.40.50.980 99 261 3.3E-47 T 10-11-2016 A4G23_RS10055 d649c50704e74fda71997d704eff6230 453 ProSitePatterns PS00455 Putative AMP-binding domain signature. 90 101 - T 10-11-2016 IPR020845 AMP-binding, conserved site A4G23_RS10055 d649c50704e74fda71997d704eff6230 453 Gene3D G3DSA:3.40.50.980 5 98 2.6E-23 T 10-11-2016 A4G23_RS10055 d649c50704e74fda71997d704eff6230 453 Gene3D G3DSA:2.30.38.10 263 347 1.3E-22 T 10-11-2016 A4G23_RS10055 d649c50704e74fda71997d704eff6230 453 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 4 378 6.8E-111 T 10-11-2016 IPR010071 Amino acid adenylation domain A4G23_RS10055 d649c50704e74fda71997d704eff6230 453 Pfam PF00501 AMP-binding enzyme 3 354 1.3E-81 T 10-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A4G23_RS10055 d649c50704e74fda71997d704eff6230 453 Pfam PF13193 AMP-binding enzyme C-terminal domain 363 439 8.8E-9 T 10-11-2016 IPR025110 AMP-binding enzyme C-terminal domain A4G23_RS10055 d649c50704e74fda71997d704eff6230 453 SUPERFAMILY SSF56801 2 451 5.23E-124 T 10-11-2016 A4G23_RS17135 bbafe62d9b1e8e18d990fd80f2ad1501 386 Gene3D G3DSA:3.40.50.300 86 253 1.5E-17 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS17135 bbafe62d9b1e8e18d990fd80f2ad1501 386 Pfam PF07728 AAA domain (dynein-related subfamily) 104 242 8.0E-36 T 10-11-2016 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 A4G23_RS17135 bbafe62d9b1e8e18d990fd80f2ad1501 386 SUPERFAMILY SSF52540 81 366 4.75E-21 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS06410 6793792e4797d58273c79538e2c12af1 661 Pfam PF00425 chorismate binding enzyme 111 370 1.9E-41 T 10-11-2016 IPR015890 Chorismate-utilising enzyme, C-terminal A4G23_RS06410 6793792e4797d58273c79538e2c12af1 661 SUPERFAMILY SSF52317 459 647 5.42E-25 T 10-11-2016 IPR029062 Class I glutamine amidotransferase-like A4G23_RS06410 6793792e4797d58273c79538e2c12af1 661 Pfam PF00117 Glutamine amidotransferase class-I 461 642 7.3E-26 T 10-11-2016 IPR017926 Glutamine amidotransferase A4G23_RS06410 6793792e4797d58273c79538e2c12af1 661 SUPERFAMILY SSF56322 63 379 2.49E-60 T 10-11-2016 IPR005801 ADC synthase GO:0009058 A4G23_RS06410 6793792e4797d58273c79538e2c12af1 661 PRINTS PR00097 Anthranilate synthase component II signature 624 637 1.1E-10 T 10-11-2016 A4G23_RS06410 6793792e4797d58273c79538e2c12af1 661 PRINTS PR00097 Anthranilate synthase component II signature 459 473 1.1E-10 T 10-11-2016 A4G23_RS06410 6793792e4797d58273c79538e2c12af1 661 PRINTS PR00097 Anthranilate synthase component II signature 538 549 1.1E-10 T 10-11-2016 A4G23_RS06410 6793792e4797d58273c79538e2c12af1 661 PRINTS PR00096 Glutamine amidotransferase superfamily signature 538 549 7.4E-12 T 10-11-2016 A4G23_RS06410 6793792e4797d58273c79538e2c12af1 661 PRINTS PR00096 Glutamine amidotransferase superfamily signature 624 637 7.4E-12 T 10-11-2016 A4G23_RS06410 6793792e4797d58273c79538e2c12af1 661 PRINTS PR00096 Glutamine amidotransferase superfamily signature 504 513 7.4E-12 T 10-11-2016 A4G23_RS06410 6793792e4797d58273c79538e2c12af1 661 Gene3D G3DSA:3.40.50.880 459 645 5.3E-30 T 10-11-2016 IPR029062 Class I glutamine amidotransferase-like A4G23_RS06410 6793792e4797d58273c79538e2c12af1 661 Gene3D G3DSA:3.60.120.10 102 379 1.7E-54 T 10-11-2016 IPR005801 ADC synthase GO:0009058 A4G23_RS13555 81941343a0d8b277b8152b5533b38112 418 Pfam PF07690 Major Facilitator Superfamily 44 380 3.2E-11 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS13555 81941343a0d8b277b8152b5533b38112 418 Gene3D G3DSA:1.20.1250.20 240 414 1.0E-7 T 10-11-2016 A4G23_RS13555 81941343a0d8b277b8152b5533b38112 418 Gene3D G3DSA:1.20.1250.20 16 200 1.2E-7 T 10-11-2016 A4G23_RS13555 81941343a0d8b277b8152b5533b38112 418 SUPERFAMILY SSF103473 16 417 3.79E-26 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS26565 97a06fea819f1bf27d58f443b333a427 441 Pfam PF00083 Sugar (and other) transporter 19 436 2.1E-36 T 10-11-2016 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 A4G23_RS26565 97a06fea819f1bf27d58f443b333a427 441 ProSitePatterns PS00217 Sugar transport proteins signature 2. 126 151 - T 10-11-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A4G23_RS26565 97a06fea819f1bf27d58f443b333a427 441 SUPERFAMILY SSF103473 14 435 1.44E-66 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS26565 97a06fea819f1bf27d58f443b333a427 441 TIGRFAM TIGR00883 2A0106: MFS transporter, metabolite:H+ symporter (MHS) family protein 22 420 1.2E-133 T 10-11-2016 IPR004736 Citrate-proton symport GO:0005215|GO:0006810|GO:0016021 A4G23_RS26565 97a06fea819f1bf27d58f443b333a427 441 Gene3D G3DSA:1.20.1250.20 15 216 1.6E-20 T 10-11-2016 A4G23_RS26565 97a06fea819f1bf27d58f443b333a427 441 Gene3D G3DSA:1.20.1250.20 235 436 9.9E-25 T 10-11-2016 A4G23_RS05655 716e296321f0c431f778cbbf5049adc7 551 Pfam PF00342 Phosphoglucose isomerase 55 541 5.2E-218 T 10-11-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4G23_RS05655 716e296321f0c431f778cbbf5049adc7 551 Gene3D G3DSA:1.10.1390.10 508 549 4.4E-18 T 10-11-2016 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4G23_RS05655 716e296321f0c431f778cbbf5049adc7 551 SUPERFAMILY SSF53697 10 549 1.75E-207 T 10-11-2016 A4G23_RS05655 716e296321f0c431f778cbbf5049adc7 551 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 49 525 41.447 T 10-11-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4G23_RS05655 716e296321f0c431f778cbbf5049adc7 551 Gene3D G3DSA:3.40.50.10490 102 295 2.6E-82 T 10-11-2016 A4G23_RS05655 716e296321f0c431f778cbbf5049adc7 551 Gene3D G3DSA:3.40.50.10490 13 101 5.6E-134 T 10-11-2016 A4G23_RS05655 716e296321f0c431f778cbbf5049adc7 551 Gene3D G3DSA:3.40.50.10490 298 507 5.6E-134 T 10-11-2016 A4G23_RS05655 716e296321f0c431f778cbbf5049adc7 551 PRINTS PR00662 Glucose-6-phosphate isomerase signature 153 172 1.8E-53 T 10-11-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4G23_RS05655 716e296321f0c431f778cbbf5049adc7 551 PRINTS PR00662 Glucose-6-phosphate isomerase signature 484 498 1.8E-53 T 10-11-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4G23_RS05655 716e296321f0c431f778cbbf5049adc7 551 PRINTS PR00662 Glucose-6-phosphate isomerase signature 266 284 1.8E-53 T 10-11-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4G23_RS05655 716e296321f0c431f778cbbf5049adc7 551 PRINTS PR00662 Glucose-6-phosphate isomerase signature 343 364 1.8E-53 T 10-11-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4G23_RS05655 716e296321f0c431f778cbbf5049adc7 551 PRINTS PR00662 Glucose-6-phosphate isomerase signature 466 484 1.8E-53 T 10-11-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4G23_RS05655 716e296321f0c431f778cbbf5049adc7 551 PRINTS PR00662 Glucose-6-phosphate isomerase signature 498 511 1.8E-53 T 10-11-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4G23_RS05655 716e296321f0c431f778cbbf5049adc7 551 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 498 515 - T 10-11-2016 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4G23_RS05120 df96b828fca8a20a372707cd502d624e 263 PIRSF PIRSF000094 2 263 1.6E-79 T 10-11-2016 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 A4G23_RS05120 df96b828fca8a20a372707cd502d624e 263 Gene3D G3DSA:3.40.50.720 3 262 2.1E-54 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS05120 df96b828fca8a20a372707cd502d624e 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 259 5.9E-62 T 10-11-2016 A4G23_RS05120 df96b828fca8a20a372707cd502d624e 263 SUPERFAMILY SSF51735 6 261 3.75E-49 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS01400 cec8ca781c7a9eaf1352b5b8c44d8c39 321 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 309 3.6E-11 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS01400 cec8ca781c7a9eaf1352b5b8c44d8c39 321 Gene3D G3DSA:1.10.3720.10 34 305 7.9E-55 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS01400 cec8ca781c7a9eaf1352b5b8c44d8c39 321 SUPERFAMILY SSF161098 36 310 1.31E-49 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS15105 f03e2e1cdfa9536104e3412ef3cdd4ef 317 SUPERFAMILY SSF51445 38 316 6.84E-35 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS15105 f03e2e1cdfa9536104e3412ef3cdd4ef 317 Gene3D G3DSA:3.20.20.80 33 316 2.2E-45 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS15105 f03e2e1cdfa9536104e3412ef3cdd4ef 317 Pfam PF02156 Glycosyl hydrolase family 26 170 228 5.0E-7 T 10-11-2016 IPR022790 Glycosyl hydrolase family 26 domain GO:0004553 A4G23_RS18975 c42874de11cc9d2785383271e0dafb93 171 Pfam PF00583 Acetyltransferase (GNAT) family 64 148 1.4E-13 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS18975 c42874de11cc9d2785383271e0dafb93 171 SUPERFAMILY SSF55729 6 161 5.4E-24 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS18975 c42874de11cc9d2785383271e0dafb93 171 Gene3D G3DSA:3.40.630.30 2 155 5.0E-23 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS22625 e1b3442ae419bb1a36debd228e2bccf6 290 SMART SM00892 46 265 2.2E-47 T 10-11-2016 IPR001604 DNA/RNA non-specific endonuclease GO:0003676|GO:0016787|GO:0046872 A4G23_RS22625 e1b3442ae419bb1a36debd228e2bccf6 290 SMART SM00477 47 265 4.4E-14 T 10-11-2016 IPR020821 Extracellular Endonuclease, subunit A GO:0003676|GO:0016787|GO:0046872 A4G23_RS22625 e1b3442ae419bb1a36debd228e2bccf6 290 Pfam PF01223 DNA/RNA non-specific endonuclease 43 259 3.9E-44 T 10-11-2016 IPR001604 DNA/RNA non-specific endonuclease GO:0003676|GO:0016787|GO:0046872 A4G23_RS22625 e1b3442ae419bb1a36debd228e2bccf6 290 SUPERFAMILY SSF54060 29 259 9.42E-46 T 10-11-2016 A4G23_RS22625 e1b3442ae419bb1a36debd228e2bccf6 290 Gene3D G3DSA:3.40.570.10 37 265 8.9E-40 T 10-11-2016 IPR020821 Extracellular Endonuclease, subunit A GO:0003676|GO:0016787|GO:0046872 A4G23_RS20830 9edf7c6fad2834b548ad025edaa71c1b 194 SUPERFAMILY SSF160631 27 83 1.31E-8 T 10-11-2016 A4G23_RS20830 9edf7c6fad2834b548ad025edaa71c1b 194 SMART SM00860 37 164 6.4E-5 T 10-11-2016 IPR018958 SMI1/KNR4-like domain A4G23_RS20830 9edf7c6fad2834b548ad025edaa71c1b 194 Pfam PF09346 SMI1 / KNR4 family (SUKH-1) 37 81 5.4E-7 T 10-11-2016 IPR018958 SMI1/KNR4-like domain A4G23_RS18815 f60748cae0af7f9087a804eba2e47f3c 226 Pfam PF01987 Mitochondrial biogenesis AIM24 18 214 3.9E-36 T 10-11-2016 IPR002838 Mitochondrial biogenesis protein AIM24 A4G23_RS18815 f60748cae0af7f9087a804eba2e47f3c 226 SUPERFAMILY SSF51219 17 217 1.02E-47 T 10-11-2016 IPR016031 Tryptophan RNA-binding attenuator protein-like domain A4G23_RS18815 f60748cae0af7f9087a804eba2e47f3c 226 Gene3D G3DSA:3.60.160.10 15 216 5.3E-43 T 10-11-2016 IPR002838 Mitochondrial biogenesis protein AIM24 A4G23_RS17875 9c0ca5b0f12bf3575f18068923987c2a 513 Gene3D G3DSA:1.20.200.10 199 509 1.1E-110 T 10-11-2016 A4G23_RS17875 9c0ca5b0f12bf3575f18068923987c2a 513 Hamap MF_00229 Histidine ammonia-lyase [hutH]. 3 507 42.664 T 10-11-2016 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A4G23_RS17875 9c0ca5b0f12bf3575f18068923987c2a 513 Pfam PF00221 Aromatic amino acid lyase 12 472 1.5E-178 T 10-11-2016 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 A4G23_RS17875 9c0ca5b0f12bf3575f18068923987c2a 513 SUPERFAMILY SSF48557 3 505 2.28E-175 T 10-11-2016 IPR008948 L-Aspartase-like GO:0003824 A4G23_RS17875 9c0ca5b0f12bf3575f18068923987c2a 513 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 4 507 1.0E-207 T 10-11-2016 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A4G23_RS17875 9c0ca5b0f12bf3575f18068923987c2a 513 Gene3D G3DSA:1.10.275.10 2 198 2.1E-72 T 10-11-2016 IPR024083 Fumarase/histidase, N-terminal A4G23_RS17875 9c0ca5b0f12bf3575f18068923987c2a 513 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 139 155 - T 10-11-2016 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 A4G23_RS09960 ce74e93e7d17a856132a02af52ad9fb5 126 Pfam PF12005 Protein of unknown function (DUF3499) 4 122 2.5E-48 T 10-11-2016 IPR021888 Protein of unknown function DUF3499 A4G23_RS10725 ac2362db94439ad74675b0a14691f0ae 191 SUPERFAMILY SSF109854 20 186 3.36E-31 T 10-11-2016 A4G23_RS10725 ac2362db94439ad74675b0a14691f0ae 191 Pfam PF04978 Protein of unknown function (DUF664) 46 187 1.5E-32 T 10-11-2016 IPR007061 Protein of unknown function DUF664 A4G23_RS10725 ac2362db94439ad74675b0a14691f0ae 191 Gene3D G3DSA:1.20.120.450 29 190 4.2E-32 T 10-11-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase A4G23_RS20825 c2d03d54e0a517ef330295b38042d86e 481 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 248 255 - T 10-11-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 A4G23_RS20825 c2d03d54e0a517ef330295b38042d86e 481 Gene3D G3DSA:3.40.605.10 5 264 5.2E-73 T 10-11-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A4G23_RS20825 c2d03d54e0a517ef330295b38042d86e 481 Gene3D G3DSA:3.40.309.10 265 450 3.0E-54 T 10-11-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 A4G23_RS20825 c2d03d54e0a517ef330295b38042d86e 481 SUPERFAMILY SSF53720 3 475 2.88E-131 T 10-11-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A4G23_RS20825 c2d03d54e0a517ef330295b38042d86e 481 Pfam PF00171 Aldehyde dehydrogenase family 18 471 2.3E-132 T 10-11-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A4G23_RS17125 d06d7cbbef07dd1327ca4e66f8f17203 441 Pfam PF04434 SWIM zinc finger 58 83 7.8E-6 T 10-11-2016 IPR007527 Zinc finger, SWIM-type GO:0008270 A4G23_RS19180 2e302b0e8c37c003409983bc809b6de8 188 SUPERFAMILY SSF52980 12 168 9.65E-19 T 10-11-2016 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A4G23_RS19180 2e302b0e8c37c003409983bc809b6de8 188 Gene3D G3DSA:3.90.1570.10 13 167 9.5E-19 T 10-11-2016 IPR012296 Nuclease, putative, TT1808 A4G23_RS19180 2e302b0e8c37c003409983bc809b6de8 188 Pfam PF05685 Putative restriction endonuclease 18 144 6.4E-19 T 10-11-2016 IPR008538 Domain of unknown function DUF820 A4G23_RS12015 43d48a5975d74c675adde888fa27230b 468 Pfam PF00982 Glycosyltransferase family 20 5 460 1.0E-98 T 10-11-2016 IPR001830 Glycosyl transferase, family 20 GO:0003824|GO:0005992 A4G23_RS12015 43d48a5975d74c675adde888fa27230b 468 SUPERFAMILY SSF53756 3 461 1.07E-107 T 10-11-2016 A4G23_RS12015 43d48a5975d74c675adde888fa27230b 468 Gene3D G3DSA:3.40.50.2000 246 442 1.4E-56 T 10-11-2016 A4G23_RS12015 43d48a5975d74c675adde888fa27230b 468 Gene3D G3DSA:3.40.50.2000 4 231 9.3E-56 T 10-11-2016 A4G23_RS13675 762adb0becbdcc8f7d30886fb0b7ad48 144 Pfam PF04686 Streptomyces sporulation and cell division protein, SsgA 23 120 7.6E-32 T 10-11-2016 IPR006776 Sporulation-specific cell division protein SsgB GO:0051301 A4G23_RS25305 3d14d5e0d2c426ef1f9efa85a0076d7b 299 SUPERFAMILY SSF102114 14 179 3.14E-13 T 10-11-2016 A4G23_RS25305 3d14d5e0d2c426ef1f9efa85a0076d7b 299 Gene3D G3DSA:3.20.20.70 17 226 4.0E-15 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS25305 3d14d5e0d2c426ef1f9efa85a0076d7b 299 Pfam PF04055 Radical SAM superfamily 25 105 3.6E-8 T 10-11-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 A4G23_RS25305 3d14d5e0d2c426ef1f9efa85a0076d7b 299 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 22 33 - T 10-11-2016 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4G23_RS19270 89fcc27022150f485c7cfa6260daab42 139 SUPERFAMILY SSF46785 12 136 1.37E-28 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS19270 89fcc27022150f485c7cfa6260daab42 139 ProSitePatterns PS01117 MarR-type HTH domain signature. 64 98 - T 10-11-2016 IPR023187 Transcriptional regulator MarR-type, conserved site A4G23_RS19270 89fcc27022150f485c7cfa6260daab42 139 Pfam PF01047 MarR family 34 89 2.1E-12 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS19270 89fcc27022150f485c7cfa6260daab42 139 Gene3D G3DSA:1.10.10.10 7 136 9.8E-31 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS19270 89fcc27022150f485c7cfa6260daab42 139 SMART SM00347 25 125 1.8E-20 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS27105 6b02ff74cdbc109db4b811a469fc97f0 562 SUPERFAMILY SSF55781 212 373 2.18E-19 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS27105 6b02ff74cdbc109db4b811a469fc97f0 562 Pfam PF13185 GAF domain 38 178 7.7E-17 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS27105 6b02ff74cdbc109db4b811a469fc97f0 562 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 471 520 6.0E-7 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS27105 6b02ff74cdbc109db4b811a469fc97f0 562 Gene3D G3DSA:3.30.450.40 187 352 3.5E-19 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS27105 6b02ff74cdbc109db4b811a469fc97f0 562 Gene3D G3DSA:3.30.450.40 21 185 1.9E-32 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS27105 6b02ff74cdbc109db4b811a469fc97f0 562 Gene3D G3DSA:3.30.565.10 451 557 3.3E-11 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS27105 6b02ff74cdbc109db4b811a469fc97f0 562 Pfam PF13492 GAF domain 218 347 5.4E-10 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS27105 6b02ff74cdbc109db4b811a469fc97f0 562 SUPERFAMILY SSF55781 21 205 2.84E-41 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS27105 6b02ff74cdbc109db4b811a469fc97f0 562 SUPERFAMILY SSF55874 438 556 5.11E-16 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS27105 6b02ff74cdbc109db4b811a469fc97f0 562 Pfam PF07730 Histidine kinase 364 426 8.7E-11 T 10-11-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4G23_RS27105 6b02ff74cdbc109db4b811a469fc97f0 562 SMART SM00387 468 558 1.6E-11 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS27105 6b02ff74cdbc109db4b811a469fc97f0 562 SMART SM00065 208 356 0.013 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS27105 6b02ff74cdbc109db4b811a469fc97f0 562 SMART SM00065 39 187 2.4E-19 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS20660 89091847246aebed640ea06d950065e5 394 SUPERFAMILY SSF53901 189 392 4.55E-52 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS20660 89091847246aebed640ea06d950065e5 394 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 256 351 1.7E-20 T 10-11-2016 IPR014031 Beta-ketoacyl synthase, C-terminal A4G23_RS20660 89091847246aebed640ea06d950065e5 394 SUPERFAMILY SSF53901 13 225 2.13E-40 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS20660 89091847246aebed640ea06d950065e5 394 SMART SM00825 Beta-ketoacyl synthase 15 394 5.0E-10 T 10-11-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4G23_RS20660 89091847246aebed640ea06d950065e5 394 Gene3D G3DSA:3.40.47.10 15 234 5.8E-34 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS20660 89091847246aebed640ea06d950065e5 394 Gene3D G3DSA:3.40.47.10 258 393 1.2E-43 T 10-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 A4G23_RS20660 89091847246aebed640ea06d950065e5 394 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 72 221 1.8E-18 T 10-11-2016 IPR014030 Beta-ketoacyl synthase, N-terminal A4G23_RS24310 3578e00306fb5943bfb074d862979bb9 164 SUPERFAMILY SSF55729 1 162 1.61E-26 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS24310 3578e00306fb5943bfb074d862979bb9 164 Pfam PF00583 Acetyltransferase (GNAT) family 59 139 2.3E-13 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS24310 3578e00306fb5943bfb074d862979bb9 164 Gene3D G3DSA:3.40.630.30 1 162 2.6E-44 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS08465 69f1bd41f7c702fe51e01c8987c74e67 178 Pfam PF14279 HNH endonuclease 83 129 3.2E-13 T 10-11-2016 IPR029471 HNH endonuclease 5 A4G23_RS08465 69f1bd41f7c702fe51e01c8987c74e67 178 SMART SM00507 70 119 1.7E-13 T 10-11-2016 IPR003615 HNH nuclease A4G23_RS10745 3277adec6af33dc861e86ec18dcbceba 554 SUPERFAMILY SSF51905 285 486 2.14E-21 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS10745 3277adec6af33dc861e86ec18dcbceba 554 Pfam PF00743 Flavin-binding monooxygenase-like 22 229 4.8E-15 T 10-11-2016 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 A4G23_RS10745 3277adec6af33dc861e86ec18dcbceba 554 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 21 37 1.4E-6 T 10-11-2016 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 A4G23_RS10745 3277adec6af33dc861e86ec18dcbceba 554 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 46 70 1.4E-6 T 10-11-2016 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 A4G23_RS10745 3277adec6af33dc861e86ec18dcbceba 554 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 131 147 1.4E-6 T 10-11-2016 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 A4G23_RS10745 3277adec6af33dc861e86ec18dcbceba 554 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 340 367 1.4E-6 T 10-11-2016 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 A4G23_RS10745 3277adec6af33dc861e86ec18dcbceba 554 SUPERFAMILY SSF51905 20 236 7.13E-56 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS10745 3277adec6af33dc861e86ec18dcbceba 554 Gene3D G3DSA:3.50.50.60 338 502 1.0E-18 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS10745 3277adec6af33dc861e86ec18dcbceba 554 Gene3D G3DSA:3.50.50.60 17 231 7.1E-63 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS25380 2f54064e5c30401f87f219b9226e4c6f 323 Gene3D G3DSA:3.40.50.1820 170 280 2.9E-8 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS25380 2f54064e5c30401f87f219b9226e4c6f 323 Gene3D G3DSA:3.40.50.1820 2 40 2.9E-8 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS25380 2f54064e5c30401f87f219b9226e4c6f 323 SUPERFAMILY SSF53474 194 277 2.42E-7 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS04890 0a2fbec6ab0a2d1b19f9900c4e12169e 426 Pfam PF02616 Segregation and condensation protein ScpA 181 401 7.2E-49 T 10-11-2016 IPR003768 Segregation and condensation protein A A4G23_RS12070 cf71f51fdde8599835d29c24cc9ddbb7 154 Gene3D G3DSA:2.30.110.10 1 154 9.3E-50 T 10-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 A4G23_RS12070 cf71f51fdde8599835d29c24cc9ddbb7 154 SMART SM00903 1 152 3.5E-52 T 10-11-2016 IPR002563 Flavin reductase like domain GO:0010181 A4G23_RS12070 cf71f51fdde8599835d29c24cc9ddbb7 154 Pfam PF01613 Flavin reductase like domain 1 153 8.9E-39 T 10-11-2016 IPR002563 Flavin reductase like domain GO:0010181 A4G23_RS12070 cf71f51fdde8599835d29c24cc9ddbb7 154 SUPERFAMILY SSF50475 1 154 6.87E-40 T 10-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 A4G23_RS26130 1246faf9c25ef41d6f2d0b224a520e15 404 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 253 393 1.2E-27 T 10-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4G23_RS26130 1246faf9c25ef41d6f2d0b224a520e15 404 SUPERFAMILY SSF56645 6 127 1.18E-14 T 10-11-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 A4G23_RS26130 1246faf9c25ef41d6f2d0b224a520e15 404 Gene3D G3DSA:1.10.540.10 4 101 7.5E-15 T 10-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 A4G23_RS26130 1246faf9c25ef41d6f2d0b224a520e15 404 Gene3D G3DSA:1.20.140.10 253 394 8.9E-35 T 10-11-2016 A4G23_RS26130 1246faf9c25ef41d6f2d0b224a520e15 404 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 102 6.9E-14 T 10-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 A4G23_RS26130 1246faf9c25ef41d6f2d0b224a520e15 404 SUPERFAMILY SSF47203 259 394 1.59E-34 T 10-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4G23_RS26850 7fc1e91051c3decaa6d548bf8ba272e6 356 Pfam PF00487 Fatty acid desaturase 69 331 3.2E-35 T 10-11-2016 IPR005804 Fatty acid desaturase domain GO:0006629 A4G23_RS26850 7fc1e91051c3decaa6d548bf8ba272e6 356 PIRSF PIRSF015921 16 355 6.5E-69 T 10-11-2016 IPR012171 Fatty acid desaturase GO:0006629|GO:0016021|GO:0016491 A4G23_RS26045 24f31e6b62a62c0b2d515adc10d2f291 438 PRINTS PR00463 E-class P450 group I signature 258 284 2.3E-23 T 10-11-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS26045 24f31e6b62a62c0b2d515adc10d2f291 438 PRINTS PR00463 E-class P450 group I signature 339 363 2.3E-23 T 10-11-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS26045 24f31e6b62a62c0b2d515adc10d2f291 438 PRINTS PR00463 E-class P450 group I signature 386 409 2.3E-23 T 10-11-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS26045 24f31e6b62a62c0b2d515adc10d2f291 438 PRINTS PR00463 E-class P450 group I signature 238 255 2.3E-23 T 10-11-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS26045 24f31e6b62a62c0b2d515adc10d2f291 438 PRINTS PR00463 E-class P450 group I signature 376 386 2.3E-23 T 10-11-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS26045 24f31e6b62a62c0b2d515adc10d2f291 438 PRINTS PR00463 E-class P450 group I signature 26 45 2.3E-23 T 10-11-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS26045 24f31e6b62a62c0b2d515adc10d2f291 438 SUPERFAMILY SSF48264 3 437 2.62E-102 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS26045 24f31e6b62a62c0b2d515adc10d2f291 438 PRINTS PR00385 P450 superfamily signature 249 266 1.9E-10 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS26045 24f31e6b62a62c0b2d515adc10d2f291 438 PRINTS PR00385 P450 superfamily signature 386 397 1.9E-10 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS26045 24f31e6b62a62c0b2d515adc10d2f291 438 PRINTS PR00385 P450 superfamily signature 377 386 1.9E-10 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS26045 24f31e6b62a62c0b2d515adc10d2f291 438 PRINTS PR00385 P450 superfamily signature 301 312 1.9E-10 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS26045 24f31e6b62a62c0b2d515adc10d2f291 438 Pfam PF00067 Cytochrome P450 3 421 3.3E-77 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS26045 24f31e6b62a62c0b2d515adc10d2f291 438 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 379 388 - T 10-11-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A4G23_RS26045 24f31e6b62a62c0b2d515adc10d2f291 438 Gene3D G3DSA:1.10.630.10 3 437 1.4E-108 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS02065 94c3038941685aa4f9f897c29fce16ae 318 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 313 5.3E-17 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS02065 94c3038941685aa4f9f897c29fce16ae 318 Gene3D G3DSA:1.10.3720.10 88 316 3.9E-64 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS02065 94c3038941685aa4f9f897c29fce16ae 318 SUPERFAMILY SSF161098 83 309 4.19E-62 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS02975 1ec0eae729f7a1221fe9a5ef00ff112e 708 Pfam PF00930 Dipeptidyl peptidase IV (DPP IV) N-terminal region 114 321 1.3E-24 T 10-11-2016 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 A4G23_RS02975 1ec0eae729f7a1221fe9a5ef00ff112e 708 Gene3D G3DSA:2.140.10.30 16 453 3.8E-52 T 10-11-2016 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 A4G23_RS02975 1ec0eae729f7a1221fe9a5ef00ff112e 708 SUPERFAMILY SSF53474 464 707 1.31E-57 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS02975 1ec0eae729f7a1221fe9a5ef00ff112e 708 Pfam PF00326 Prolyl oligopeptidase family 508 707 1.3E-44 T 10-11-2016 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 A4G23_RS02975 1ec0eae729f7a1221fe9a5ef00ff112e 708 SUPERFAMILY SSF82171 95 391 7.32E-19 T 10-11-2016 A4G23_RS02975 1ec0eae729f7a1221fe9a5ef00ff112e 708 SUPERFAMILY SSF82171 16 34 7.32E-19 T 10-11-2016 A4G23_RS02975 1ec0eae729f7a1221fe9a5ef00ff112e 708 Gene3D G3DSA:3.40.50.1820 464 706 1.1E-68 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS15270 51d1de4f7e9121a16a40cb0f66e25978 677 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 119 610 3.0E-232 T 10-11-2016 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 A4G23_RS15270 51d1de4f7e9121a16a40cb0f66e25978 677 Pfam PF01434 Peptidase family M41 402 609 2.9E-80 T 10-11-2016 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 A4G23_RS15270 51d1de4f7e9121a16a40cb0f66e25978 677 SMART SM00382 203 342 6.2E-25 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS15270 51d1de4f7e9121a16a40cb0f66e25978 677 ProSitePatterns PS00674 AAA-protein family signature. 310 328 - T 10-11-2016 IPR003960 ATPase, AAA-type, conserved site GO:0005524 A4G23_RS15270 51d1de4f7e9121a16a40cb0f66e25978 677 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 5 619 37.228 T 10-11-2016 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 A4G23_RS15270 51d1de4f7e9121a16a40cb0f66e25978 677 SUPERFAMILY SSF52540 161 411 7.04E-71 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS15270 51d1de4f7e9121a16a40cb0f66e25978 677 SUPERFAMILY SSF140990 421 619 1.14E-73 T 10-11-2016 A4G23_RS15270 51d1de4f7e9121a16a40cb0f66e25978 677 Gene3D G3DSA:3.40.50.300 163 347 7.2E-62 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS15270 51d1de4f7e9121a16a40cb0f66e25978 677 Gene3D G3DSA:1.10.8.60 348 414 7.7E-24 T 10-11-2016 A4G23_RS15270 51d1de4f7e9121a16a40cb0f66e25978 677 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 207 339 9.6E-45 T 10-11-2016 IPR003959 ATPase, AAA-type, core GO:0005524 A4G23_RS25175 2fb205721c2229c8ad734bc5e7fd7234 179 Pfam PF01161 Phosphatidylethanolamine-binding protein 41 174 2.8E-31 T 10-11-2016 IPR008914 Phosphatidylethanolamine-binding protein A4G23_RS25175 2fb205721c2229c8ad734bc5e7fd7234 179 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 41 171 1.1E-35 T 10-11-2016 IPR005247 YbhB/YbcL A4G23_RS25175 2fb205721c2229c8ad734bc5e7fd7234 179 Gene3D G3DSA:3.90.280.10 20 175 6.6E-46 T 10-11-2016 IPR008914 Phosphatidylethanolamine-binding protein A4G23_RS25175 2fb205721c2229c8ad734bc5e7fd7234 179 SUPERFAMILY SSF49777 25 174 8.63E-43 T 10-11-2016 IPR008914 Phosphatidylethanolamine-binding protein A4G23_RS26135 f4c65a5b6c739179d942a0ea0b12a59e 538 Gene3D G3DSA:3.10.105.10 292 494 4.2E-43 T 10-11-2016 A4G23_RS26135 f4c65a5b6c739179d942a0ea0b12a59e 538 Gene3D G3DSA:3.40.190.10 160 291 2.6E-40 T 10-11-2016 A4G23_RS26135 f4c65a5b6c739179d942a0ea0b12a59e 538 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 83 439 9.9E-89 T 10-11-2016 IPR000914 Solute-binding protein family 5 domain A4G23_RS26135 f4c65a5b6c739179d942a0ea0b12a59e 538 PIRSF PIRSF002741 8 528 1.0E-101 T 10-11-2016 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A4G23_RS26135 f4c65a5b6c739179d942a0ea0b12a59e 538 SUPERFAMILY SSF53850 42 511 2.35E-118 T 10-11-2016 A4G23_RS26135 f4c65a5b6c739179d942a0ea0b12a59e 538 Gene3D G3DSA:3.90.76.10 72 159 7.8E-27 T 10-11-2016 A4G23_RS27010 677cb2058d4b2bd0ae812748953225dc 166 Pfam PF04542 Sigma-70 region 2 10 73 2.8E-12 T 10-11-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS27010 677cb2058d4b2bd0ae812748953225dc 166 Gene3D G3DSA:1.10.1740.10 3 73 2.6E-16 T 10-11-2016 A4G23_RS27010 677cb2058d4b2bd0ae812748953225dc 166 Pfam PF08281 Sigma-70, region 4 100 150 9.6E-14 T 10-11-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS27010 677cb2058d4b2bd0ae812748953225dc 166 SUPERFAMILY SSF88659 98 155 7.63E-14 T 10-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS27010 677cb2058d4b2bd0ae812748953225dc 166 Gene3D G3DSA:1.10.10.10 99 157 9.8E-17 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS27010 677cb2058d4b2bd0ae812748953225dc 166 SUPERFAMILY SSF88946 3 72 2.83E-15 T 10-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS27010 677cb2058d4b2bd0ae812748953225dc 166 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 5 154 1.0E-17 T 10-11-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS18970 e68ac19bf49e26c9e42498d0682db147 792 Gene3D G3DSA:3.20.70.20 604 649 6.6E-80 T 10-11-2016 A4G23_RS18970 e68ac19bf49e26c9e42498d0682db147 792 Gene3D G3DSA:3.20.70.20 400 559 6.6E-80 T 10-11-2016 A4G23_RS18970 e68ac19bf49e26c9e42498d0682db147 792 Gene3D G3DSA:3.20.70.20 149 350 6.6E-80 T 10-11-2016 A4G23_RS18970 e68ac19bf49e26c9e42498d0682db147 792 Pfam PF02867 Ribonucleotide reductase, barrel domain 228 749 1.0E-175 T 10-11-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4G23_RS18970 e68ac19bf49e26c9e42498d0682db147 792 PRINTS PR01183 Ribonucleotide reductase large chain signature 304 323 5.9E-50 T 10-11-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4G23_RS18970 e68ac19bf49e26c9e42498d0682db147 792 PRINTS PR01183 Ribonucleotide reductase large chain signature 473 496 5.9E-50 T 10-11-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4G23_RS18970 e68ac19bf49e26c9e42498d0682db147 792 PRINTS PR01183 Ribonucleotide reductase large chain signature 539 562 5.9E-50 T 10-11-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4G23_RS18970 e68ac19bf49e26c9e42498d0682db147 792 PRINTS PR01183 Ribonucleotide reductase large chain signature 604 631 5.9E-50 T 10-11-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4G23_RS18970 e68ac19bf49e26c9e42498d0682db147 792 PRINTS PR01183 Ribonucleotide reductase large chain signature 511 533 5.9E-50 T 10-11-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4G23_RS18970 e68ac19bf49e26c9e42498d0682db147 792 PRINTS PR01183 Ribonucleotide reductase large chain signature 436 447 5.9E-50 T 10-11-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4G23_RS18970 e68ac19bf49e26c9e42498d0682db147 792 SUPERFAMILY SSF51998 227 653 6.41E-176 T 10-11-2016 A4G23_RS18970 e68ac19bf49e26c9e42498d0682db147 792 SUPERFAMILY SSF51998 684 754 6.41E-176 T 10-11-2016 A4G23_RS18970 e68ac19bf49e26c9e42498d0682db147 792 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 151 753 2.9E-227 T 10-11-2016 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4G23_RS18970 e68ac19bf49e26c9e42498d0682db147 792 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 148 224 3.5E-21 T 10-11-2016 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4G23_RS18970 e68ac19bf49e26c9e42498d0682db147 792 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 593 615 - T 10-11-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4G23_RS18970 e68ac19bf49e26c9e42498d0682db147 792 SUPERFAMILY SSF48168 31 226 6.93E-47 T 10-11-2016 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4G23_RS04770 9b55dd07ee5af9399edaf44f48726582 604 Gene3D G3DSA:1.20.1250.20 24 203 4.3E-31 T 10-11-2016 A4G23_RS04770 9b55dd07ee5af9399edaf44f48726582 604 Gene3D G3DSA:1.20.1250.20 483 512 1.8E-13 T 10-11-2016 A4G23_RS04770 9b55dd07ee5af9399edaf44f48726582 604 Gene3D G3DSA:1.20.1250.20 280 431 1.8E-13 T 10-11-2016 A4G23_RS04770 9b55dd07ee5af9399edaf44f48726582 604 PRINTS PR01036 Tetracycline resistance protein TetB signature 148 172 1.2E-8 T 10-11-2016 A4G23_RS04770 9b55dd07ee5af9399edaf44f48726582 604 PRINTS PR01036 Tetracycline resistance protein TetB signature 26 50 1.2E-8 T 10-11-2016 A4G23_RS04770 9b55dd07ee5af9399edaf44f48726582 604 PRINTS PR01036 Tetracycline resistance protein TetB signature 86 108 1.2E-8 T 10-11-2016 A4G23_RS04770 9b55dd07ee5af9399edaf44f48726582 604 PRINTS PR01036 Tetracycline resistance protein TetB signature 411 430 1.2E-8 T 10-11-2016 A4G23_RS04770 9b55dd07ee5af9399edaf44f48726582 604 SUPERFAMILY SSF103473 482 511 6.54E-61 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS04770 9b55dd07ee5af9399edaf44f48726582 604 SUPERFAMILY SSF103473 259 430 6.54E-61 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS04770 9b55dd07ee5af9399edaf44f48726582 604 SUPERFAMILY SSF103473 15 207 6.54E-61 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS04770 9b55dd07ee5af9399edaf44f48726582 604 Pfam PF07690 Major Facilitator Superfamily 28 420 4.8E-45 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS16890 c9ef36a9eeed23a7b4b0042d2a3f4198 184 Gene3D G3DSA:3.40.630.30 5 182 2.2E-30 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS16890 c9ef36a9eeed23a7b4b0042d2a3f4198 184 Pfam PF00583 Acetyltransferase (GNAT) family 89 160 7.8E-15 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS16890 c9ef36a9eeed23a7b4b0042d2a3f4198 184 SUPERFAMILY SSF55729 5 181 4.61E-26 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS06665 cb12de4129d20dc855e25702b13274a4 363 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 17 344 6.0E-100 T 10-11-2016 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 A4G23_RS06665 cb12de4129d20dc855e25702b13274a4 363 SUPERFAMILY SSF52733 9 343 7.98E-91 T 10-11-2016 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 A4G23_RS06665 cb12de4129d20dc855e25702b13274a4 363 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 15 354 31.43 T 10-11-2016 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 A4G23_RS06665 cb12de4129d20dc855e25702b13274a4 363 Gene3D G3DSA:1.10.1610.10 16 68 3.6E-17 T 10-11-2016 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 A4G23_RS06665 cb12de4129d20dc855e25702b13274a4 363 Pfam PF02277 Phosphoribosyltransferase 13 343 2.2E-102 T 10-11-2016 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 A4G23_RS06665 cb12de4129d20dc855e25702b13274a4 363 Gene3D G3DSA:3.40.50.10210 69 335 1.9E-88 T 10-11-2016 A4G23_RS16255 be3be008263ff5d1971d999d65c375d8 167 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 82 162 5.3E-29 T 10-11-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A4G23_RS16255 be3be008263ff5d1971d999d65c375d8 167 SUPERFAMILY SSF46767 81 165 6.8E-28 T 10-11-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A4G23_RS16255 be3be008263ff5d1971d999d65c375d8 167 SUPERFAMILY SSF53155 3 87 1.35E-11 T 10-11-2016 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A4G23_RS16255 be3be008263ff5d1971d999d65c375d8 167 Gene3D G3DSA:1.10.10.10 81 165 4.5E-32 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS16255 be3be008263ff5d1971d999d65c375d8 167 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 83 163 1.4E-28 T 10-11-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A4G23_RS17280 5f5e6cc8345fd7dc7bf5fee9e1bc281a 329 SUPERFAMILY SSF53850 48 328 9.5E-59 T 10-11-2016 A4G23_RS17280 5f5e6cc8345fd7dc7bf5fee9e1bc281a 329 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 50 317 4.5E-48 T 10-11-2016 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 A4G23_RS17280 5f5e6cc8345fd7dc7bf5fee9e1bc281a 329 Gene3D G3DSA:3.40.190.10 47 144 1.9E-12 T 10-11-2016 A4G23_RS17280 5f5e6cc8345fd7dc7bf5fee9e1bc281a 329 Gene3D G3DSA:3.40.190.100 145 274 7.1E-25 T 10-11-2016 A4G23_RS20110 d3bf6753bf14ff0d9fe53b65cac24f84 312 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 105 277 8.1E-44 T 10-11-2016 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A4G23_RS20110 d3bf6753bf14ff0d9fe53b65cac24f84 312 SUPERFAMILY SSF52283 55 116 1.76E-5 T 10-11-2016 A4G23_RS20110 d3bf6753bf14ff0d9fe53b65cac24f84 312 Gene3D G3DSA:3.40.50.720 114 278 1.6E-49 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS20110 d3bf6753bf14ff0d9fe53b65cac24f84 312 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 50 308 2.1E-8 T 10-11-2016 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 A4G23_RS20110 d3bf6753bf14ff0d9fe53b65cac24f84 312 Gene3D G3DSA:3.40.50.720 34 113 7.8E-17 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS20110 d3bf6753bf14ff0d9fe53b65cac24f84 312 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 217 233 - T 10-11-2016 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A4G23_RS20110 d3bf6753bf14ff0d9fe53b65cac24f84 312 SUPERFAMILY SSF51735 98 278 5.64E-43 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS08065 7de783ca38735293749e8713a9a2591c 155 Pfam PF02410 Ribosomal silencing factor during starvation 14 109 2.0E-21 T 10-11-2016 A4G23_RS08065 7de783ca38735293749e8713a9a2591c 155 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 7 110 22.851 T 10-11-2016 IPR004394 Protein Iojap/ribosomal silencing factor RsfS A4G23_RS08065 7de783ca38735293749e8713a9a2591c 155 Gene3D G3DSA:3.30.460.10 7 113 1.8E-32 T 10-11-2016 A4G23_RS08065 7de783ca38735293749e8713a9a2591c 155 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 11 109 3.7E-29 T 10-11-2016 IPR004394 Protein Iojap/ribosomal silencing factor RsfS A4G23_RS08065 7de783ca38735293749e8713a9a2591c 155 SUPERFAMILY SSF81301 7 118 2.45E-34 T 10-11-2016 A4G23_RS02955 b0946271909c4e7af53a65c2d46db836 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 1.5E-11 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS02955 b0946271909c4e7af53a65c2d46db836 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 1.5E-11 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS02955 b0946271909c4e7af53a65c2d46db836 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 1.5E-11 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS02955 b0946271909c4e7af53a65c2d46db836 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 10-11-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4G23_RS02955 b0946271909c4e7af53a65c2d46db836 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 5.2E-40 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS02955 b0946271909c4e7af53a65c2d46db836 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 5.2E-40 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS02955 b0946271909c4e7af53a65c2d46db836 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 5.2E-40 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS02955 b0946271909c4e7af53a65c2d46db836 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 5.2E-40 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS02955 b0946271909c4e7af53a65c2d46db836 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 5.2E-40 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS02955 b0946271909c4e7af53a65c2d46db836 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 5.2E-40 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS02955 b0946271909c4e7af53a65c2d46db836 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 20 248 5.7E-53 T 10-11-2016 A4G23_RS02955 b0946271909c4e7af53a65c2d46db836 255 Gene3D G3DSA:3.40.50.720 10 250 3.5E-72 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS02955 b0946271909c4e7af53a65c2d46db836 255 SUPERFAMILY SSF51735 11 249 5.82E-73 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS04635 d87c4e3b1e97dc0d191efb137ff1617a 232 SUPERFAMILY SSF46689 2 69 3.29E-16 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS04635 d87c4e3b1e97dc0d191efb137ff1617a 232 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 77 206 6.7E-15 T 10-11-2016 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 A4G23_RS04635 d87c4e3b1e97dc0d191efb137ff1617a 232 Gene3D G3DSA:1.10.357.10 2 209 1.5E-61 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS04635 d87c4e3b1e97dc0d191efb137ff1617a 232 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 1.4E-13 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS04635 d87c4e3b1e97dc0d191efb137ff1617a 232 ProSitePatterns PS01081 TetR-type HTH domain signature. 26 57 - T 10-11-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A4G23_RS04635 d87c4e3b1e97dc0d191efb137ff1617a 232 PRINTS PR00400 Tetracycline repressor protein signature 26 49 4.6E-11 T 10-11-2016 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 A4G23_RS04635 d87c4e3b1e97dc0d191efb137ff1617a 232 PRINTS PR00400 Tetracycline repressor protein signature 81 100 4.6E-11 T 10-11-2016 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 A4G23_RS04635 d87c4e3b1e97dc0d191efb137ff1617a 232 PRINTS PR00400 Tetracycline repressor protein signature 190 204 4.6E-11 T 10-11-2016 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 A4G23_RS04635 d87c4e3b1e97dc0d191efb137ff1617a 232 SUPERFAMILY SSF48498 80 208 5.89E-27 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS04635 d87c4e3b1e97dc0d191efb137ff1617a 232 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 3.5E-7 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS04635 d87c4e3b1e97dc0d191efb137ff1617a 232 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 3.5E-7 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS12175 947fd1133615372874b9b8a9a59b8f43 633 Gene3D G3DSA:3.90.420.10 332 523 5.2E-45 T 10-11-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 A4G23_RS12175 947fd1133615372874b9b8a9a59b8f43 633 SUPERFAMILY SSF81296 518 627 2.45E-23 T 10-11-2016 IPR014756 Immunoglobulin E-set A4G23_RS12175 947fd1133615372874b9b8a9a59b8f43 633 Gene3D G3DSA:2.60.40.650 524 611 7.5E-20 T 10-11-2016 IPR005066 Moybdenum cofactor oxidoreductase, dimerisation GO:0016491|GO:0030151|GO:0055114 Reactome: R-HSA-1614517 A4G23_RS12175 947fd1133615372874b9b8a9a59b8f43 633 SUPERFAMILY SSF56524 333 525 3.4E-48 T 10-11-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 A4G23_RS12175 947fd1133615372874b9b8a9a59b8f43 633 Pfam PF00174 Oxidoreductase molybdopterin binding domain 349 500 1.0E-32 T 10-11-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 A4G23_RS20450 056d140e6c47669502c42febdd3bbf82 471 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 21 470 1.2E-97 T 10-11-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 A4G23_RS20450 056d140e6c47669502c42febdd3bbf82 471 ProSitePatterns PS00216 Sugar transport proteins signature 1. 327 344 - T 10-11-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A4G23_RS20450 056d140e6c47669502c42febdd3bbf82 471 Pfam PF00083 Sugar (and other) transporter 26 470 4.1E-103 T 10-11-2016 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 A4G23_RS20450 056d140e6c47669502c42febdd3bbf82 471 ProSitePatterns PS00217 Sugar transport proteins signature 2. 121 146 - T 10-11-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A4G23_RS20450 056d140e6c47669502c42febdd3bbf82 471 Gene3D G3DSA:1.20.1250.20 28 223 1.5E-22 T 10-11-2016 A4G23_RS20450 056d140e6c47669502c42febdd3bbf82 471 Gene3D G3DSA:1.20.1250.20 273 469 2.8E-18 T 10-11-2016 A4G23_RS20450 056d140e6c47669502c42febdd3bbf82 471 SUPERFAMILY SSF103473 19 470 6.54E-67 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS20450 056d140e6c47669502c42febdd3bbf82 471 PRINTS PR00171 Sugar transporter signature 116 135 3.4E-20 T 10-11-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 A4G23_RS20450 056d140e6c47669502c42febdd3bbf82 471 PRINTS PR00171 Sugar transporter signature 33 43 3.4E-20 T 10-11-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 A4G23_RS20450 056d140e6c47669502c42febdd3bbf82 471 PRINTS PR00171 Sugar transporter signature 399 411 3.4E-20 T 10-11-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 A4G23_RS20450 056d140e6c47669502c42febdd3bbf82 471 PRINTS PR00171 Sugar transporter signature 283 293 3.4E-20 T 10-11-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 A4G23_RS20450 056d140e6c47669502c42febdd3bbf82 471 PRINTS PR00171 Sugar transporter signature 376 397 3.4E-20 T 10-11-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 A4G23_RS13850 7626f17524fe26d97e51ce427323c8ce 114 SUPERFAMILY SSF55874 16 111 1.03E-7 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS13850 7626f17524fe26d97e51ce427323c8ce 114 Pfam PF13581 Histidine kinase-like ATPase domain 4 105 3.3E-12 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS13850 7626f17524fe26d97e51ce427323c8ce 114 Gene3D G3DSA:3.30.565.10 2 108 5.2E-4 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS05720 750249f94238ae86464e0a65134f945d 218 SMART SM00849 32 197 4.7E-30 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS05720 750249f94238ae86464e0a65134f945d 218 Gene3D G3DSA:3.60.15.10 25 203 1.4E-46 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS05720 750249f94238ae86464e0a65134f945d 218 Pfam PF00753 Metallo-beta-lactamase superfamily 29 197 6.4E-12 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS05720 750249f94238ae86464e0a65134f945d 218 SUPERFAMILY SSF56281 22 214 1.9E-42 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS01960 95b2333760fabb1fe19cce8d97dde657 359 Gene3D G3DSA:3.90.1150.10 269 355 4.7E-26 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS01960 95b2333760fabb1fe19cce8d97dde657 359 Pfam PF01212 Beta-eliminating lyase 22 307 2.7E-53 T 10-11-2016 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 A4G23_RS01960 95b2333760fabb1fe19cce8d97dde657 359 SUPERFAMILY SSF53383 20 355 3.62E-92 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS01960 95b2333760fabb1fe19cce8d97dde657 359 Gene3D G3DSA:3.40.640.10 14 266 1.2E-58 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS08510 e01b6fd1c551a930ec7466281feb8494 156 Pfam PF16918 Protein kinase G tetratricopeptide repeat 1 154 2.1E-11 T 10-11-2016 IPR031636 Protein kinase G, tetratricopeptide repeat containing domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 A4G23_RS06435 724a4ed3654cb577250b72e480b604e9 267 PIRSF PIRSF017388 1 248 1.0E-76 T 10-11-2016 IPR012354 Esterase/lipase GO:0052689 A4G23_RS06435 724a4ed3654cb577250b72e480b604e9 267 Pfam PF12146 Serine aminopeptidase, S33 19 229 1.4E-23 T 10-11-2016 IPR022742 Serine aminopeptidase, S33 A4G23_RS06435 724a4ed3654cb577250b72e480b604e9 267 Gene3D G3DSA:3.40.50.1820 12 245 3.4E-52 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS06435 724a4ed3654cb577250b72e480b604e9 267 SUPERFAMILY SSF53474 13 121 4.19E-37 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS06435 724a4ed3654cb577250b72e480b604e9 267 SUPERFAMILY SSF53474 174 245 4.19E-37 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS02620 55d0e02ce9e05d285f1599f036285f72 338 Pfam PF00571 CBS domain 284 333 2.3E-8 T 10-11-2016 IPR000644 CBS domain A4G23_RS02620 55d0e02ce9e05d285f1599f036285f72 338 Pfam PF00571 CBS domain 216 272 4.1E-5 T 10-11-2016 IPR000644 CBS domain A4G23_RS02620 55d0e02ce9e05d285f1599f036285f72 338 SMART SM00116 285 333 2.3E-4 T 10-11-2016 IPR000644 CBS domain A4G23_RS02620 55d0e02ce9e05d285f1599f036285f72 338 SMART SM00116 225 273 0.057 T 10-11-2016 IPR000644 CBS domain A4G23_RS02620 55d0e02ce9e05d285f1599f036285f72 338 Pfam PF01595 Domain of unknown function DUF21 8 198 1.2E-39 T 10-11-2016 IPR002550 Domain of unknown function DUF21 A4G23_RS02620 55d0e02ce9e05d285f1599f036285f72 338 Gene3D G3DSA:3.10.580.10 222 332 1.7E-20 T 10-11-2016 A4G23_RS02620 55d0e02ce9e05d285f1599f036285f72 338 SUPERFAMILY SSF54631 205 334 3.54E-27 T 10-11-2016 A4G23_RS13530 7582b0d5d4a3b3b62ef526436029b0bd 233 Pfam PF08281 Sigma-70, region 4 128 180 2.0E-15 T 10-11-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS13530 7582b0d5d4a3b3b62ef526436029b0bd 233 Gene3D G3DSA:1.10.1740.10 7 117 1.3E-30 T 10-11-2016 A4G23_RS13530 7582b0d5d4a3b3b62ef526436029b0bd 233 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 23 180 1.2E-28 T 10-11-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS13530 7582b0d5d4a3b3b62ef526436029b0bd 233 Gene3D G3DSA:1.10.10.10 122 184 3.2E-22 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS13530 7582b0d5d4a3b3b62ef526436029b0bd 233 SUPERFAMILY SSF88659 121 184 6.54E-16 T 10-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS13530 7582b0d5d4a3b3b62ef526436029b0bd 233 Pfam PF04542 Sigma-70 region 2 28 93 9.2E-17 T 10-11-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS13530 7582b0d5d4a3b3b62ef526436029b0bd 233 SUPERFAMILY SSF88946 7 113 1.45E-28 T 10-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS22320 b1c2c515ce76cb775630cac674ce9b3b 306 Gene3D G3DSA:1.10.600.10 168 239 4.9E-6 T 10-11-2016 IPR008949 Isoprenoid synthase domain A4G23_RS22320 b1c2c515ce76cb775630cac674ce9b3b 306 SUPERFAMILY SSF48576 95 296 3.74E-8 T 10-11-2016 IPR008949 Isoprenoid synthase domain A4G23_RS21990 e836d860a1c4207e2a0694bb7aa395b0 403 Pfam PF16483 Beta-1,3-glucanase 45 400 9.9E-98 T 10-11-2016 IPR032477 Beta-1,3-glucanase, N-terminal KEGG: 00500+3.2.1.39 A4G23_RS09540 0a5be10666d9265da687fe7716421016 161 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 50 2.1E-9 T 10-11-2016 A4G23_RS09540 0a5be10666d9265da687fe7716421016 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 1.6E-9 T 10-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 A4G23_RS09540 0a5be10666d9265da687fe7716421016 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 1.6E-9 T 10-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 A4G23_RS09540 0a5be10666d9265da687fe7716421016 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 1.6E-9 T 10-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 A4G23_RS09540 0a5be10666d9265da687fe7716421016 161 SUPERFAMILY SSF54909 63 148 2.15E-17 T 10-11-2016 IPR011008 Dimeric alpha-beta barrel A4G23_RS09540 0a5be10666d9265da687fe7716421016 161 Gene3D G3DSA:3.30.70.920 56 140 6.2E-19 T 10-11-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A4G23_RS09540 0a5be10666d9265da687fe7716421016 161 Gene3D G3DSA:1.10.10.10 3 53 3.0E-13 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS09540 0a5be10666d9265da687fe7716421016 161 Pfam PF01037 Lrp/AsnC ligand binding domain 72 138 1.2E-13 T 10-11-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A4G23_RS09540 0a5be10666d9265da687fe7716421016 161 SMART SM00344 3 109 4.3E-27 T 10-11-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A4G23_RS09540 0a5be10666d9265da687fe7716421016 161 SUPERFAMILY SSF46785 2 63 6.85E-11 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS21815 a124729b3f60d08c2b448dbcce5f3d08 290 Gene3D G3DSA:1.10.10.10 198 254 4.4E-10 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS21815 a124729b3f60d08c2b448dbcce5f3d08 290 SUPERFAMILY SSF46785 187 254 6.82E-9 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS21815 a124729b3f60d08c2b448dbcce5f3d08 290 SMART SM00418 194 262 0.0015 T 10-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4G23_RS21815 a124729b3f60d08c2b448dbcce5f3d08 290 Pfam PF12840 Helix-turn-helix domain 198 246 5.6E-7 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS19925 114ad55760dca6b2709856be7c3392c0 71 SUPERFAMILY SSF47473 4 67 1.3E-17 T 10-11-2016 IPR011992 EF-hand domain pair A4G23_RS19925 114ad55760dca6b2709856be7c3392c0 71 Gene3D G3DSA:1.10.238.10 5 70 4.4E-17 T 10-11-2016 IPR011992 EF-hand domain pair A4G23_RS19925 114ad55760dca6b2709856be7c3392c0 71 ProSitePatterns PS00018 EF-hand calcium-binding domain. 52 64 - T 10-11-2016 IPR018247 EF-Hand 1, calcium-binding site A4G23_RS19925 114ad55760dca6b2709856be7c3392c0 71 Pfam PF13499 EF-hand domain pair 7 64 8.0E-12 T 10-11-2016 IPR002048 EF-hand domain GO:0005509 A4G23_RS19925 114ad55760dca6b2709856be7c3392c0 71 ProSitePatterns PS00018 EF-hand calcium-binding domain. 15 27 - T 10-11-2016 IPR018247 EF-Hand 1, calcium-binding site A4G23_RS19925 114ad55760dca6b2709856be7c3392c0 71 SMART SM00054 6 34 1.8E-4 T 10-11-2016 IPR002048 EF-hand domain GO:0005509 A4G23_RS19925 114ad55760dca6b2709856be7c3392c0 71 SMART SM00054 43 71 86.0 T 10-11-2016 IPR002048 EF-hand domain GO:0005509 A4G23_RS26690 44c6b62ef8622a7261dfb72d09ee700b 209 SMART SM00849 24 188 9.6E-38 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS26690 44c6b62ef8622a7261dfb72d09ee700b 209 Pfam PF00753 Metallo-beta-lactamase superfamily 25 188 3.1E-24 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS26690 44c6b62ef8622a7261dfb72d09ee700b 209 Gene3D G3DSA:3.60.15.10 9 206 1.3E-45 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS26690 44c6b62ef8622a7261dfb72d09ee700b 209 SUPERFAMILY SSF56281 10 200 1.97E-47 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS21670 f200de40a89f2c76674a66e13b892d7d 369 Pfam PF00155 Aminotransferase class I and II 49 353 4.7E-40 T 10-11-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4G23_RS21670 f200de40a89f2c76674a66e13b892d7d 369 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 207 216 - T 10-11-2016 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 A4G23_RS21670 f200de40a89f2c76674a66e13b892d7d 369 Gene3D G3DSA:3.90.1150.10 230 355 6.9E-23 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS21670 f200de40a89f2c76674a66e13b892d7d 369 SUPERFAMILY SSF53383 38 355 1.6E-80 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS21670 f200de40a89f2c76674a66e13b892d7d 369 TIGRFAM TIGR03947 viomycin_VioD: capreomycidine synthase 1 357 2.4E-176 T 10-11-2016 IPR023965 Capreomycidine synthase A4G23_RS21670 f200de40a89f2c76674a66e13b892d7d 369 Gene3D G3DSA:3.40.640.10 46 229 1.1E-51 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS19065 8e0557cf899a43087b7acdc1fbe86121 292 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 11 282 1.2E-18 T 10-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4G23_RS19065 8e0557cf899a43087b7acdc1fbe86121 292 SUPERFAMILY SSF53686 2 282 1.44E-50 T 10-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4G23_RS19065 8e0557cf899a43087b7acdc1fbe86121 292 PIRSF PIRSF006278 1 288 7.9E-79 T 10-11-2016 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase A4G23_RS19065 8e0557cf899a43087b7acdc1fbe86121 292 Gene3D G3DSA:3.40.50.1100 90 282 2.0E-41 T 10-11-2016 A4G23_RS09990 19d302f5676d9d92abbe68bad4106088 318 TIGRFAM TIGR01819 F420_cofD: 2-phospho-L-lactate transferase 3 309 4.7E-133 T 10-11-2016 IPR010115 2-phospho-L-lactate transferase GO:0000287|GO:0016780|GO:0051188 KEGG: 00680+2.7.8.28|MetaCyc: PWY-5198 A4G23_RS09990 19d302f5676d9d92abbe68bad4106088 318 Gene3D G3DSA:3.40.50.10680 87 316 3.9E-81 T 10-11-2016 A4G23_RS09990 19d302f5676d9d92abbe68bad4106088 318 Hamap MF_01257 2-phospho-L-lactate transferase [cofD]. 1 318 137.484 T 10-11-2016 IPR010115 2-phospho-L-lactate transferase GO:0000287|GO:0016780|GO:0051188 KEGG: 00680+2.7.8.28|MetaCyc: PWY-5198 A4G23_RS09990 19d302f5676d9d92abbe68bad4106088 318 Pfam PF01933 Uncharacterised protein family UPF0052 4 278 4.0E-61 T 10-11-2016 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 A4G23_RS09990 19d302f5676d9d92abbe68bad4106088 318 SUPERFAMILY SSF142338 3 314 8.5E-86 T 10-11-2016 A4G23_RS22055 daf035b4ee5696c5488b49a36da70cd5 414 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 150 165 5.3E-7 T 10-11-2016 A4G23_RS22055 daf035b4ee5696c5488b49a36da70cd5 414 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 5.3E-7 T 10-11-2016 A4G23_RS22055 daf035b4ee5696c5488b49a36da70cd5 414 Pfam PF01494 FAD binding domain 2 344 2.5E-23 T 10-11-2016 IPR002938 FAD-binding domain GO:0071949 A4G23_RS22055 daf035b4ee5696c5488b49a36da70cd5 414 SUPERFAMILY SSF51905 1 171 1.35E-49 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS22055 daf035b4ee5696c5488b49a36da70cd5 414 SUPERFAMILY SSF51905 265 359 1.35E-49 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS22055 daf035b4ee5696c5488b49a36da70cd5 414 Gene3D G3DSA:3.50.50.60 274 337 2.4E-33 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS22055 daf035b4ee5696c5488b49a36da70cd5 414 Gene3D G3DSA:3.50.50.60 1 176 2.4E-33 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS24825 7b99dbf5d640e7977c455496bd4dcba1 247 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 244 1.2E-41 T 10-11-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 A4G23_RS24825 7b99dbf5d640e7977c455496bd4dcba1 247 Gene3D G3DSA:3.90.226.10 4 240 2.2E-65 T 10-11-2016 IPR029045 ClpP/crotonase-like domain A4G23_RS24825 7b99dbf5d640e7977c455496bd4dcba1 247 SUPERFAMILY SSF52096 4 244 7.4E-69 T 10-11-2016 IPR029045 ClpP/crotonase-like domain A4G23_RS17865 c906ab9900196bf8ca9beb7486415680 277 Gene3D G3DSA:1.10.12.10 219 277 1.8E-17 T 10-11-2016 IPR014748 Crontonase, C-terminal A4G23_RS17865 c906ab9900196bf8ca9beb7486415680 277 Pfam PF00378 Enoyl-CoA hydratase/isomerase 31 275 3.2E-57 T 10-11-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 A4G23_RS17865 c906ab9900196bf8ca9beb7486415680 277 Gene3D G3DSA:3.90.226.10 22 218 9.1E-64 T 10-11-2016 IPR029045 ClpP/crotonase-like domain A4G23_RS17865 c906ab9900196bf8ca9beb7486415680 277 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 119 139 - T 10-11-2016 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 A4G23_RS17865 c906ab9900196bf8ca9beb7486415680 277 SUPERFAMILY SSF52096 21 276 2.34E-78 T 10-11-2016 IPR029045 ClpP/crotonase-like domain A4G23_RS26755 30a59661ab53eb90e8e04ba70e2a1c1e 401 SUPERFAMILY SSF51569 9 389 2.27E-136 T 10-11-2016 A4G23_RS26755 30a59661ab53eb90e8e04ba70e2a1c1e 401 Pfam PF01474 Class-II DAHP synthetase family 181 384 4.6E-74 T 10-11-2016 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 A4G23_RS26755 30a59661ab53eb90e8e04ba70e2a1c1e 401 Pfam PF01474 Class-II DAHP synthetase family 9 166 8.7E-46 T 10-11-2016 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 A4G23_RS24520 446afe8ab62bf53f9a055d4e67370888 283 SUPERFAMILY SSF51735 9 263 1.16E-31 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS24520 446afe8ab62bf53f9a055d4e67370888 283 Gene3D G3DSA:3.40.50.720 8 210 2.0E-21 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS26215 420ed3a53d1a15c30196d274200dd420 320 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 4 301 2.9E-74 T 10-11-2016 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain A4G23_RS26215 420ed3a53d1a15c30196d274200dd420 320 Gene3D G3DSA:3.90.245.10 1 308 1.2E-109 T 10-11-2016 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain A4G23_RS26215 420ed3a53d1a15c30196d274200dd420 320 SUPERFAMILY SSF53590 2 308 3.66E-99 T 10-11-2016 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain A4G23_RS13750 af2588cf215bf7d1f9a5e871ef868986 589 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 459 487 - T 10-11-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4G23_RS13750 af2588cf215bf7d1f9a5e871ef868986 589 Gene3D G3DSA:3.40.50.720 321 562 8.0E-69 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS13750 af2588cf215bf7d1f9a5e871ef868986 589 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 322 508 0.0051 T 10-11-2016 A4G23_RS13750 af2588cf215bf7d1f9a5e871ef868986 589 Gene3D G3DSA:3.40.50.1820 5 295 3.9E-49 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS13750 af2588cf215bf7d1f9a5e871ef868986 589 SUPERFAMILY SSF53474 7 297 6.06E-45 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS13750 af2588cf215bf7d1f9a5e871ef868986 589 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 398 409 3.3E-28 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS13750 af2588cf215bf7d1f9a5e871ef868986 589 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 323 340 3.3E-28 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS13750 af2588cf215bf7d1f9a5e871ef868986 589 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 493 510 3.3E-28 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS13750 af2588cf215bf7d1f9a5e871ef868986 589 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 446 462 3.3E-28 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS13750 af2588cf215bf7d1f9a5e871ef868986 589 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 472 491 3.3E-28 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS13750 af2588cf215bf7d1f9a5e871ef868986 589 SUPERFAMILY SSF51735 318 585 1.19E-69 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS13750 af2588cf215bf7d1f9a5e871ef868986 589 Pfam PF00106 short chain dehydrogenase 323 513 1.3E-54 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS13750 af2588cf215bf7d1f9a5e871ef868986 589 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 452 460 2.1E-13 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS13750 af2588cf215bf7d1f9a5e871ef868986 589 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 472 491 2.1E-13 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS13750 af2588cf215bf7d1f9a5e871ef868986 589 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 398 409 2.1E-13 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS13750 af2588cf215bf7d1f9a5e871ef868986 589 Pfam PF00561 alpha/beta hydrolase fold 30 148 2.1E-19 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS10180 73028f3d938ff45a92101fa0fabdb91a 903 Gene3D G3DSA:2.60.40.10 412 503 1.4E-10 T 10-11-2016 IPR013783 Immunoglobulin-like fold A4G23_RS10180 73028f3d938ff45a92101fa0fabdb91a 903 SUPERFAMILY SSF49899 511 731 3.34E-30 T 10-11-2016 IPR013320 Concanavalin A-like lectin/glucanase domain A4G23_RS10180 73028f3d938ff45a92101fa0fabdb91a 903 Gene3D G3DSA:2.60.120.200 512 731 5.3E-26 T 10-11-2016 IPR013320 Concanavalin A-like lectin/glucanase domain A4G23_RS10180 73028f3d938ff45a92101fa0fabdb91a 903 SUPERFAMILY SSF49265 412 525 8.83E-8 T 10-11-2016 IPR003961 Fibronectin type III GO:0005515 A4G23_RS10180 73028f3d938ff45a92101fa0fabdb91a 903 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 573 726 1.3E-21 T 10-11-2016 A4G23_RS10180 73028f3d938ff45a92101fa0fabdb91a 903 SMART SM00560 584 723 0.002 T 10-11-2016 IPR006558 LamG-like jellyroll fold A4G23_RS10180 73028f3d938ff45a92101fa0fabdb91a 903 SUPERFAMILY SSF50998 286 303 3.22E-11 T 10-11-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily A4G23_RS10180 73028f3d938ff45a92101fa0fabdb91a 903 SUPERFAMILY SSF50998 35 254 3.22E-11 T 10-11-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily A4G23_RS20665 f1dc9f5031d65a0f479e3750e6920615 266 Pfam PF04672 S-adenosyl methyltransferase 5 266 2.5E-96 T 10-11-2016 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type A4G23_RS20665 f1dc9f5031d65a0f479e3750e6920615 266 SUPERFAMILY SSF53335 15 254 5.48E-45 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS20665 f1dc9f5031d65a0f479e3750e6920615 266 Gene3D G3DSA:3.40.50.150 5 266 3.2E-104 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS20665 f1dc9f5031d65a0f479e3750e6920615 266 PIRSF PIRSF017393 1 266 5.7E-95 T 10-11-2016 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type A4G23_RS16955 32b35f988a25f28a6fe1960f9e1d0aaf 104 Pfam PF02467 Transcription factor WhiB 17 87 5.4E-25 T 10-11-2016 IPR003482 Transcription factor WhiB A4G23_RS16955 32b35f988a25f28a6fe1960f9e1d0aaf 104 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 93 19.681 T 10-11-2016 IPR003482 Transcription factor WhiB A4G23_RS17555 b106f1542c4cc2db4eed8c55815d2596 296 Pfam PF03102 NeuB family 40 276 5.7E-79 T 10-11-2016 IPR013132 N-acetylneuraminic acid synthase, N-terminal GO:0016051 Reactome: R-HSA-4085001 A4G23_RS17555 b106f1542c4cc2db4eed8c55815d2596 296 Gene3D G3DSA:3.20.20.70 9 276 4.8E-98 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS17555 b106f1542c4cc2db4eed8c55815d2596 296 SUPERFAMILY SSF51569 9 286 1.83E-83 T 10-11-2016 A4G23_RS15825 55c66eb38a74d0c130dfc402488ea1d9 215 SUPERFAMILY SSF53254 1 188 2.21E-35 T 10-11-2016 IPR029033 Histidine phosphatase superfamily A4G23_RS15825 55c66eb38a74d0c130dfc402488ea1d9 215 SMART SM00855 1 149 5.4E-11 T 10-11-2016 IPR013078 Histidine phosphatase superfamily, clade-1 A4G23_RS15825 55c66eb38a74d0c130dfc402488ea1d9 215 Gene3D G3DSA:3.40.50.1240 1 185 3.1E-29 T 10-11-2016 IPR029033 Histidine phosphatase superfamily A4G23_RS15825 55c66eb38a74d0c130dfc402488ea1d9 215 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 1 185 1.6E-35 T 10-11-2016 IPR013078 Histidine phosphatase superfamily, clade-1 A4G23_RS21630 5e4941eaa0f4f20bf6bbe011b334ccb2 302 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 42 49 - T 10-11-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A4G23_RS21630 5e4941eaa0f4f20bf6bbe011b334ccb2 302 Gene3D G3DSA:3.40.50.1370 136 286 1.0E-38 T 10-11-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A4G23_RS21630 5e4941eaa0f4f20bf6bbe011b334ccb2 302 SUPERFAMILY SSF53671 2 300 2.88E-69 T 10-11-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A4G23_RS21630 5e4941eaa0f4f20bf6bbe011b334ccb2 302 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 2 136 4.0E-31 T 10-11-2016 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 A4G23_RS21630 5e4941eaa0f4f20bf6bbe011b334ccb2 302 PRINTS PR00102 Ornithine carbamoyltransferase signature 40 54 2.7E-12 T 10-11-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4G23_RS21630 5e4941eaa0f4f20bf6bbe011b334ccb2 302 PRINTS PR00102 Ornithine carbamoyltransferase signature 73 86 2.7E-12 T 10-11-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4G23_RS21630 5e4941eaa0f4f20bf6bbe011b334ccb2 302 PRINTS PR00102 Ornithine carbamoyltransferase signature 114 128 2.7E-12 T 10-11-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4G23_RS21630 5e4941eaa0f4f20bf6bbe011b334ccb2 302 PRINTS PR00102 Ornithine carbamoyltransferase signature 218 228 2.7E-12 T 10-11-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4G23_RS21630 5e4941eaa0f4f20bf6bbe011b334ccb2 302 Gene3D G3DSA:3.40.50.1370 2 135 8.5E-37 T 10-11-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A4G23_RS21630 5e4941eaa0f4f20bf6bbe011b334ccb2 302 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 125 136 2.5E-18 T 10-11-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A4G23_RS21630 5e4941eaa0f4f20bf6bbe011b334ccb2 302 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 253 262 2.5E-18 T 10-11-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A4G23_RS21630 5e4941eaa0f4f20bf6bbe011b334ccb2 302 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 265 288 2.5E-18 T 10-11-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A4G23_RS21630 5e4941eaa0f4f20bf6bbe011b334ccb2 302 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 42 61 2.5E-18 T 10-11-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A4G23_RS21630 5e4941eaa0f4f20bf6bbe011b334ccb2 302 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 144 298 1.5E-27 T 10-11-2016 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 A4G23_RS01635 da9a80c1552534763159c5556a387b60 307 Gene3D G3DSA:3.30.420.40 2 143 5.9E-36 T 10-11-2016 A4G23_RS01635 da9a80c1552534763159c5556a387b60 307 ProSitePatterns PS01125 ROK family signature. 139 166 - T 10-11-2016 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A4G23_RS01635 da9a80c1552534763159c5556a387b60 307 SUPERFAMILY SSF53067 3 307 1.07E-58 T 10-11-2016 A4G23_RS01635 da9a80c1552534763159c5556a387b60 307 Gene3D G3DSA:3.30.420.40 144 292 2.2E-49 T 10-11-2016 A4G23_RS01635 da9a80c1552534763159c5556a387b60 307 Pfam PF00480 ROK family 4 305 9.5E-65 T 10-11-2016 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A4G23_RS03050 f3e5b6ccdd5574624f6d18d47c867629 345 Gene3D G3DSA:3.30.1490.100 235 341 1.0E-30 T 10-11-2016 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A4G23_RS03050 f3e5b6ccdd5574624f6d18d47c867629 345 SUPERFAMILY SSF100879 232 332 1.73E-26 T 10-11-2016 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A4G23_RS03050 f3e5b6ccdd5574624f6d18d47c867629 345 Gene3D G3DSA:3.30.70.270 58 157 7.5E-25 T 10-11-2016 A4G23_RS03050 f3e5b6ccdd5574624f6d18d47c867629 345 Gene3D G3DSA:1.10.150.20 159 228 1.3E-20 T 10-11-2016 A4G23_RS03050 f3e5b6ccdd5574624f6d18d47c867629 345 SUPERFAMILY SSF56672 1 228 3.29E-70 T 10-11-2016 A4G23_RS03050 f3e5b6ccdd5574624f6d18d47c867629 345 Hamap MF_01113 DNA polymerase IV [dinB]. 1 341 32.698 T 10-11-2016 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 A4G23_RS03050 f3e5b6ccdd5574624f6d18d47c867629 345 Pfam PF11799 impB/mucB/samB family C-terminal domain 230 335 3.9E-20 T 10-11-2016 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A4G23_RS03050 f3e5b6ccdd5574624f6d18d47c867629 345 Pfam PF00817 impB/mucB/samB family 1 147 1.3E-43 T 10-11-2016 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A4G23_RS10895 f9f3d9746bf4d88a40f2810dd5ff5669 940 PIRSF PIRSF001227 20 940 8.0E-260 T 10-11-2016 IPR014395 Penicillin acylase GO:0016811 A4G23_RS10895 f9f3d9746bf4d88a40f2810dd5ff5669 940 Gene3D G3DSA:3.60.20.10 506 716 6.6E-119 T 10-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal A4G23_RS10895 f9f3d9746bf4d88a40f2810dd5ff5669 940 Gene3D G3DSA:3.60.20.10 333 414 6.6E-119 T 10-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal A4G23_RS10895 f9f3d9746bf4d88a40f2810dd5ff5669 940 Gene3D G3DSA:3.60.20.10 761 778 6.6E-119 T 10-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal A4G23_RS10895 f9f3d9746bf4d88a40f2810dd5ff5669 940 SUPERFAMILY SSF56235 321 940 9.0E-213 T 10-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal A4G23_RS10895 f9f3d9746bf4d88a40f2810dd5ff5669 940 SUPERFAMILY SSF56235 58 252 9.0E-213 T 10-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal A4G23_RS10895 f9f3d9746bf4d88a40f2810dd5ff5669 940 Pfam PF01804 Penicillin amidase 62 929 2.9E-243 T 10-11-2016 IPR002692 Penicillin/cephalosporin acylase GO:0016787|GO:0017000 A4G23_RS10895 f9f3d9746bf4d88a40f2810dd5ff5669 940 Gene3D G3DSA:2.30.120.10 415 497 2.2E-19 T 10-11-2016 A4G23_RS10895 f9f3d9746bf4d88a40f2810dd5ff5669 940 Gene3D G3DSA:1.10.439.10 47 222 3.9E-62 T 10-11-2016 IPR023343 Penicillin amidase type, domain1 GO:0016811 A4G23_RS12275 326b3dde5b7b087485ec315dec64e663 411 SMART SM00331 183 408 1.1E-13 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS12275 326b3dde5b7b087485ec315dec64e663 411 SUPERFAMILY SSF52172 22 150 5.27E-10 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS12275 326b3dde5b7b087485ec315dec64e663 411 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 212 408 7.5E-37 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS12275 326b3dde5b7b087485ec315dec64e663 411 Gene3D G3DSA:3.40.50.2300 24 150 2.1E-12 T 10-11-2016 A4G23_RS12275 326b3dde5b7b087485ec315dec64e663 411 Pfam PF00072 Response regulator receiver domain 27 130 2.7E-5 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS01950 c3e6c800c3f2a894a3835071422f74b7 101 Pfam PF00085 Thioredoxin 8 86 1.5E-8 T 10-11-2016 IPR013766 Thioredoxin domain GO:0045454 A4G23_RS01950 c3e6c800c3f2a894a3835071422f74b7 101 Gene3D G3DSA:3.40.30.10 8 96 4.5E-14 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS01950 c3e6c800c3f2a894a3835071422f74b7 101 SUPERFAMILY SSF52833 8 91 4.87E-16 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS09840 17751360c47a5824e49f408266c9f82a 256 Pfam PF00072 Response regulator receiver domain 42 153 2.0E-27 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS09840 17751360c47a5824e49f408266c9f82a 256 Gene3D G3DSA:3.40.50.2300 36 159 4.8E-38 T 10-11-2016 A4G23_RS09840 17751360c47a5824e49f408266c9f82a 256 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 207 223 8.4E-16 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS09840 17751360c47a5824e49f408266c9f82a 256 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 193 207 8.4E-16 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS09840 17751360c47a5824e49f408266c9f82a 256 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 223 235 8.4E-16 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS09840 17751360c47a5824e49f408266c9f82a 256 Gene3D G3DSA:1.10.10.10 160 254 9.3E-34 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS09840 17751360c47a5824e49f408266c9f82a 256 SMART SM00421 190 247 3.2E-28 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS09840 17751360c47a5824e49f408266c9f82a 256 SMART SM00448 40 153 2.4E-32 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS09840 17751360c47a5824e49f408266c9f82a 256 SUPERFAMILY SSF52172 39 171 3.42E-36 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS09840 17751360c47a5824e49f408266c9f82a 256 Pfam PF00196 Bacterial regulatory proteins, luxR family 192 247 4.8E-23 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS09840 17751360c47a5824e49f408266c9f82a 256 ProSitePatterns PS00622 LuxR-type HTH domain signature. 207 234 - T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS09840 17751360c47a5824e49f408266c9f82a 256 SUPERFAMILY SSF46894 176 253 4.08E-24 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS05950 4e77044af58c0f67afbc82b8b87c9582 244 Pfam PF10138 vWA found in TerF C terminus 35 237 2.9E-67 T 10-11-2016 IPR019303 vWA found in TerF C terminus A4G23_RS05950 4e77044af58c0f67afbc82b8b87c9582 244 Gene3D G3DSA:3.40.50.410 36 177 1.8E-8 T 10-11-2016 IPR002035 von Willebrand factor, type A A4G23_RS05950 4e77044af58c0f67afbc82b8b87c9582 244 SUPERFAMILY SSF53300 36 193 4.45E-18 T 10-11-2016 IPR002035 von Willebrand factor, type A A4G23_RS05950 4e77044af58c0f67afbc82b8b87c9582 244 SMART SM00327 35 209 1.7E-12 T 10-11-2016 IPR002035 von Willebrand factor, type A A4G23_RS26080 f12359cd377798be348b92597062df92 821 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 536 642 9.3E-8 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS26080 f12359cd377798be348b92597062df92 821 Gene3D G3DSA:3.30.565.10 498 641 1.4E-15 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS26080 f12359cd377798be348b92597062df92 821 Pfam PF08376 Nitrate and nitrite sensing 73 298 2.5E-26 T 10-11-2016 IPR013587 Nitrate/nitrite sensing protein A4G23_RS26080 f12359cd377798be348b92597062df92 821 SMART SM00387 532 644 2.5E-8 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS26080 f12359cd377798be348b92597062df92 821 SUPERFAMILY SSF55874 534 642 1.7E-16 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS07585 7e14ee844e3a01cdf6a233cdd95bfef7 409 Pfam PF07690 Major Facilitator Superfamily 22 318 2.0E-15 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS07585 7e14ee844e3a01cdf6a233cdd95bfef7 409 Gene3D G3DSA:1.20.1250.20 21 190 7.7E-12 T 10-11-2016 A4G23_RS07585 7e14ee844e3a01cdf6a233cdd95bfef7 409 Gene3D G3DSA:1.20.1250.20 210 394 1.5E-16 T 10-11-2016 A4G23_RS07585 7e14ee844e3a01cdf6a233cdd95bfef7 409 SUPERFAMILY SSF103473 19 389 1.96E-37 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS08610 20f32fe5d4938640a8d9b029c130018d 451 Gene3D G3DSA:3.40.50.300 164 362 2.7E-15 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS08610 20f32fe5d4938640a8d9b029c130018d 451 SUPERFAMILY SSF52540 153 365 6.77E-14 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS08610 20f32fe5d4938640a8d9b029c130018d 451 Pfam PF01580 FtsK/SpoIIIE family 140 333 1.8E-39 T 10-11-2016 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 A4G23_RS01860 4aed32cc8bfc6911f78caa37fc2bcd20 458 Gene3D G3DSA:3.40.630.10 364 453 5.4E-59 T 10-11-2016 A4G23_RS01860 4aed32cc8bfc6911f78caa37fc2bcd20 458 Gene3D G3DSA:3.40.630.10 10 197 5.4E-59 T 10-11-2016 A4G23_RS01860 4aed32cc8bfc6911f78caa37fc2bcd20 458 Pfam PF01546 Peptidase family M20/M25/M40 90 442 7.4E-35 T 10-11-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A4G23_RS01860 4aed32cc8bfc6911f78caa37fc2bcd20 458 SUPERFAMILY SSF53187 365 453 1.0E-53 T 10-11-2016 A4G23_RS01860 4aed32cc8bfc6911f78caa37fc2bcd20 458 SUPERFAMILY SSF53187 9 203 1.0E-53 T 10-11-2016 A4G23_RS01860 4aed32cc8bfc6911f78caa37fc2bcd20 458 Pfam PF07687 Peptidase dimerisation domain 203 351 6.8E-15 T 10-11-2016 IPR011650 Peptidase M20, dimerisation domain A4G23_RS01860 4aed32cc8bfc6911f78caa37fc2bcd20 458 Gene3D G3DSA:3.30.70.360 203 360 1.7E-38 T 10-11-2016 IPR011650 Peptidase M20, dimerisation domain A4G23_RS25870 9a981c6a30a1ea8b0f1be1c61a96dbb5 242 Pfam PF13444 Acetyltransferase (GNAT) domain 21 122 1.6E-32 T 10-11-2016 A4G23_RS25870 9a981c6a30a1ea8b0f1be1c61a96dbb5 242 SUPERFAMILY SSF55729 3 212 7.62E-40 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS25870 9a981c6a30a1ea8b0f1be1c61a96dbb5 242 Gene3D G3DSA:3.40.630.30 7 206 1.1E-29 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS24930 f1304d99e9e5a43777b6ef4eeb1a3fb9 203 Gene3D G3DSA:2.60.120.10 85 184 9.6E-17 T 10-11-2016 IPR014710 RmlC-like jelly roll fold A4G23_RS24930 f1304d99e9e5a43777b6ef4eeb1a3fb9 203 SUPERFAMILY SSF47413 14 76 3.22E-17 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS24930 f1304d99e9e5a43777b6ef4eeb1a3fb9 203 Pfam PF13560 Helix-turn-helix domain 15 73 6.1E-18 T 10-11-2016 A4G23_RS24930 f1304d99e9e5a43777b6ef4eeb1a3fb9 203 Gene3D G3DSA:1.10.260.40 15 84 4.4E-20 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS24930 f1304d99e9e5a43777b6ef4eeb1a3fb9 203 SMART SM00530 18 73 2.4E-18 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS24930 f1304d99e9e5a43777b6ef4eeb1a3fb9 203 Pfam PF07883 Cupin domain 127 182 3.8E-13 T 10-11-2016 IPR013096 Cupin 2, conserved barrel A4G23_RS24930 f1304d99e9e5a43777b6ef4eeb1a3fb9 203 SUPERFAMILY SSF51182 83 184 3.06E-22 T 10-11-2016 IPR011051 RmlC-like cupin domain A4G23_RS10890 f7257aea5b4fe4f525a73d91deb4fd30 197 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 4 185 3.4E-44 T 10-11-2016 IPR002698 5-formyltetrahydrofolate cyclo-ligase A4G23_RS10890 f7257aea5b4fe4f525a73d91deb4fd30 197 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 4 185 2.7E-40 T 10-11-2016 IPR002698 5-formyltetrahydrofolate cyclo-ligase A4G23_RS10890 f7257aea5b4fe4f525a73d91deb4fd30 197 Gene3D G3DSA:3.40.50.10420 3 191 2.2E-49 T 10-11-2016 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain A4G23_RS10890 f7257aea5b4fe4f525a73d91deb4fd30 197 PIRSF PIRSF006806 1 188 7.6E-34 T 10-11-2016 IPR002698 5-formyltetrahydrofolate cyclo-ligase A4G23_RS10890 f7257aea5b4fe4f525a73d91deb4fd30 197 SUPERFAMILY SSF100950 3 191 1.14E-42 T 10-11-2016 A4G23_RS13780 f6e80b548d9aca7dbd8d41716240ffb6 268 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 8 235 3.1E-23 T 10-11-2016 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 A4G23_RS13780 f6e80b548d9aca7dbd8d41716240ffb6 268 Pfam PF08282 haloacid dehalogenase-like hydrolase 9 260 1.3E-43 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS13780 f6e80b548d9aca7dbd8d41716240ffb6 268 SUPERFAMILY SSF56784 5 266 3.01E-57 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS13780 f6e80b548d9aca7dbd8d41716240ffb6 268 Gene3D G3DSA:3.40.50.1000 171 266 1.0E-48 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS13780 f6e80b548d9aca7dbd8d41716240ffb6 268 Gene3D G3DSA:3.40.50.1000 5 76 1.0E-48 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS24410 7cf56fa36e99da87ba8860a2b94caadb 618 SUPERFAMILY SSF52518 300 474 2.85E-53 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS24410 7cf56fa36e99da87ba8860a2b94caadb 618 Gene3D G3DSA:3.40.50.920 484 612 1.4E-34 T 10-11-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 A4G23_RS24410 7cf56fa36e99da87ba8860a2b94caadb 618 SMART SM00861 309 472 2.2E-44 T 10-11-2016 IPR005475 Transketolase-like, pyrimidine-binding domain A4G23_RS24410 7cf56fa36e99da87ba8860a2b94caadb 618 Pfam PF02779 Transketolase, pyrimidine binding domain 308 471 7.3E-37 T 10-11-2016 IPR005475 Transketolase-like, pyrimidine-binding domain A4G23_RS24410 7cf56fa36e99da87ba8860a2b94caadb 618 SUPERFAMILY SSF52518 4 264 4.79E-81 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS24410 7cf56fa36e99da87ba8860a2b94caadb 618 Gene3D G3DSA:3.40.50.970 304 483 4.6E-57 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS24410 7cf56fa36e99da87ba8860a2b94caadb 618 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 12 261 9.4E-51 T 10-11-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A4G23_RS24410 7cf56fa36e99da87ba8860a2b94caadb 618 Gene3D G3DSA:3.40.50.970 4 261 1.0E-85 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS24410 7cf56fa36e99da87ba8860a2b94caadb 618 SUPERFAMILY SSF52922 477 611 8.25E-31 T 10-11-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 A4G23_RS24410 7cf56fa36e99da87ba8860a2b94caadb 618 Pfam PF02780 Transketolase, C-terminal domain 486 605 5.0E-32 T 10-11-2016 IPR033248 Transketolase, C-terminal domain A4G23_RS24410 7cf56fa36e99da87ba8860a2b94caadb 618 ProSitePatterns PS00802 Transketolase signature 2. 415 431 - T 10-11-2016 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A4G23_RS09855 868308fe68ebce43ad52ab8b22e72733 620 SUPERFAMILY SSF63829 375 603 2.16E-10 T 10-11-2016 A4G23_RS09855 868308fe68ebce43ad52ab8b22e72733 620 Gene3D G3DSA:2.120.10.30 377 586 5.5E-10 T 10-11-2016 IPR011042 Six-bladed beta-propeller, TolB-like A4G23_RS09855 868308fe68ebce43ad52ab8b22e72733 620 Pfam PF10646 Sporulation and spore germination 202 322 3.0E-8 T 10-11-2016 IPR019606 GerMN domain A4G23_RS09855 868308fe68ebce43ad52ab8b22e72733 620 Pfam PF10647 Lipoprotein LpqB beta-propeller domain 369 619 1.2E-45 T 10-11-2016 IPR018910 Lipoprotein LpqB, beta-propeller domain, C-terminal A4G23_RS09855 868308fe68ebce43ad52ab8b22e72733 620 SMART SM00909 230 326 2.5E-11 T 10-11-2016 IPR019606 GerMN domain A4G23_RS09855 868308fe68ebce43ad52ab8b22e72733 620 Hamap MF_01373 Lipoprotein LpqB [lpqB]. 9 620 21.212 T 10-11-2016 IPR023959 Lipoprotein LpqB A4G23_RS05135 6c258cf42233df4391ebdd027b972d24 286 Gene3D G3DSA:1.10.260.40 21 79 5.1E-13 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS05135 6c258cf42233df4391ebdd027b972d24 286 SUPERFAMILY SSF47413 25 79 1.96E-11 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS05135 6c258cf42233df4391ebdd027b972d24 286 SMART SM00530 30 84 3.0E-8 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS05135 6c258cf42233df4391ebdd027b972d24 286 Pfam PF13560 Helix-turn-helix domain 27 78 1.5E-12 T 10-11-2016 A4G23_RS00590 26139776c53f1365505d2e19bef31e1e 753 SUPERFAMILY SSF48576 375 698 1.09E-61 T 10-11-2016 IPR008949 Isoprenoid synthase domain A4G23_RS00590 26139776c53f1365505d2e19bef31e1e 753 Gene3D G3DSA:1.10.600.10 363 703 1.1E-93 T 10-11-2016 IPR008949 Isoprenoid synthase domain A4G23_RS00590 26139776c53f1365505d2e19bef31e1e 753 Gene3D G3DSA:1.10.600.10 4 324 2.3E-111 T 10-11-2016 IPR008949 Isoprenoid synthase domain A4G23_RS00590 26139776c53f1365505d2e19bef31e1e 753 SUPERFAMILY SSF48576 3 331 3.17E-68 T 10-11-2016 IPR008949 Isoprenoid synthase domain A4G23_RS17190 b0a371c1af5329dbe6c85a145855c1de 247 SUPERFAMILY SSF56281 2 240 2.82E-17 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS17190 b0a371c1af5329dbe6c85a145855c1de 247 Gene3D G3DSA:3.60.15.10 3 236 9.3E-36 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS17190 b0a371c1af5329dbe6c85a145855c1de 247 Pfam PF12706 Beta-lactamase superfamily domain 19 216 1.0E-14 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS15545 b696267e27a98b9f9d0cca5947ea357c 333 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 1 330 37.155 T 10-11-2016 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 A4G23_RS15545 b696267e27a98b9f9d0cca5947ea357c 333 Pfam PF00579 tRNA synthetases class I (W and Y) 3 284 7.4E-65 T 10-11-2016 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4G23_RS15545 b696267e27a98b9f9d0cca5947ea357c 333 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 14 30 3.3E-22 T 10-11-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A4G23_RS15545 b696267e27a98b9f9d0cca5947ea357c 333 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 65 84 3.3E-22 T 10-11-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A4G23_RS15545 b696267e27a98b9f9d0cca5947ea357c 333 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 144 165 3.3E-22 T 10-11-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A4G23_RS15545 b696267e27a98b9f9d0cca5947ea357c 333 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 197 207 3.3E-22 T 10-11-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A4G23_RS15545 b696267e27a98b9f9d0cca5947ea357c 333 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 10 19 - T 10-11-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4G23_RS15545 b696267e27a98b9f9d0cca5947ea357c 333 Gene3D G3DSA:1.10.240.10 217 317 3.0E-12 T 10-11-2016 A4G23_RS15545 b696267e27a98b9f9d0cca5947ea357c 333 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 2 329 2.3E-93 T 10-11-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A4G23_RS15545 b696267e27a98b9f9d0cca5947ea357c 333 Gene3D G3DSA:3.40.50.620 2 216 5.5E-79 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS15545 b696267e27a98b9f9d0cca5947ea357c 333 SUPERFAMILY SSF52374 1 329 9.85E-79 T 10-11-2016 A4G23_RS04035 1d7736eb850fe4549ba9198a70a901b0 161 Gene3D G3DSA:1.10.357.10 11 88 9.7E-14 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS04035 1d7736eb850fe4549ba9198a70a901b0 161 SUPERFAMILY SSF48498 11 120 4.34E-14 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS04035 1d7736eb850fe4549ba9198a70a901b0 161 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 4 89 1.3E-5 T 10-11-2016 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 A4G23_RS15750 65df6e5b60293255ab6fe1efaa9d3878 641 Pfam PF13560 Helix-turn-helix domain 4 65 1.0E-13 T 10-11-2016 A4G23_RS15750 65df6e5b60293255ab6fe1efaa9d3878 641 SMART SM00530 7 63 6.6E-6 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS15750 65df6e5b60293255ab6fe1efaa9d3878 641 Gene3D G3DSA:1.10.260.40 4 65 2.4E-6 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS15750 65df6e5b60293255ab6fe1efaa9d3878 641 SUPERFAMILY SSF47413 4 64 1.76E-6 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS25220 68801b4f23fe4e619c6aeb23558972d7 113 Gene3D G3DSA:3.30.750.24 22 110 8.4E-5 T 10-11-2016 IPR002645 STAS domain A4G23_RS25220 68801b4f23fe4e619c6aeb23558972d7 113 SUPERFAMILY SSF52091 22 109 9.61E-7 T 10-11-2016 IPR002645 STAS domain A4G23_RS10245 de441dae8b646f16f7bfe217660c384f 443 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 61 79 1.0E-10 T 10-11-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A4G23_RS10245 de441dae8b646f16f7bfe217660c384f 443 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 194 207 1.0E-10 T 10-11-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A4G23_RS10245 de441dae8b646f16f7bfe217660c384f 443 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 81 93 1.0E-10 T 10-11-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A4G23_RS10245 de441dae8b646f16f7bfe217660c384f 443 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 280 299 1.0E-10 T 10-11-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A4G23_RS10245 de441dae8b646f16f7bfe217660c384f 443 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 385 398 1.0E-10 T 10-11-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A4G23_RS10245 de441dae8b646f16f7bfe217660c384f 443 SUPERFAMILY SSF50621 256 405 2.09E-29 T 10-11-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A4G23_RS10245 de441dae8b646f16f7bfe217660c384f 443 Gene3D G3DSA:2.40.37.10 277 430 9.5E-30 T 10-11-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A4G23_RS10245 de441dae8b646f16f7bfe217660c384f 443 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 341 401 2.5E-6 T 10-11-2016 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 A4G23_RS10245 de441dae8b646f16f7bfe217660c384f 443 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 57 290 1.3E-33 T 10-11-2016 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 A4G23_RS10245 de441dae8b646f16f7bfe217660c384f 443 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 230 247 - T 10-11-2016 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site A4G23_RS10245 de441dae8b646f16f7bfe217660c384f 443 Gene3D G3DSA:3.20.20.10 37 276 6.6E-59 T 10-11-2016 IPR029066 PLP-binding barrel A4G23_RS10245 de441dae8b646f16f7bfe217660c384f 443 SUPERFAMILY SSF51419 35 293 3.6E-52 T 10-11-2016 IPR029066 PLP-binding barrel A4G23_RS07875 30db18b49ade7b4f0aef3371dbbb7e89 118 SUPERFAMILY SSF142906 2 115 1.09E-38 T 10-11-2016 A4G23_RS07875 30db18b49ade7b4f0aef3371dbbb7e89 118 Pfam PF04237 YjbR 11 102 5.3E-28 T 10-11-2016 IPR007351 Uncharacterised protein YjbR A4G23_RS16095 638bf750574a568adeb1b85cb991dad9 99 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 1 99 19.406 T 10-11-2016 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 A4G23_RS16095 638bf750574a568adeb1b85cb991dad9 99 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 6 93 1.6E-22 T 10-11-2016 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 A4G23_RS07610 ac1355bad2df5d5b3978393bee361d81 410 SUPERFAMILY SSF53383 43 403 3.36E-111 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS07610 ac1355bad2df5d5b3978393bee361d81 410 Gene3D G3DSA:3.40.640.10 21 269 1.3E-79 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS07610 ac1355bad2df5d5b3978393bee361d81 410 Gene3D G3DSA:3.90.1150.10 270 405 4.0E-50 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS07610 ac1355bad2df5d5b3978393bee361d81 410 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 23 402 2.3E-124 T 10-11-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A4G23_RS07610 ac1355bad2df5d5b3978393bee361d81 410 PIRSF PIRSF001434 12 406 2.0E-123 T 10-11-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A4G23_RS23820 6d3a8e4135ea5476f596644c2327df5c 286 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 239 255 7.3E-8 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS23820 6d3a8e4135ea5476f596644c2327df5c 286 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 255 267 7.3E-8 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS23820 6d3a8e4135ea5476f596644c2327df5c 286 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 225 239 7.3E-8 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS23820 6d3a8e4135ea5476f596644c2327df5c 286 SUPERFAMILY SSF55781 2 129 1.41E-9 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS23820 6d3a8e4135ea5476f596644c2327df5c 286 Gene3D G3DSA:1.10.10.10 225 285 8.4E-19 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS23820 6d3a8e4135ea5476f596644c2327df5c 286 Pfam PF00196 Bacterial regulatory proteins, luxR family 224 278 4.1E-13 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS23820 6d3a8e4135ea5476f596644c2327df5c 286 SMART SM00421 222 279 4.1E-15 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS23820 6d3a8e4135ea5476f596644c2327df5c 286 Gene3D G3DSA:3.30.450.40 2 125 5.7E-8 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS23820 6d3a8e4135ea5476f596644c2327df5c 286 SUPERFAMILY SSF46894 221 285 1.7E-16 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS23820 6d3a8e4135ea5476f596644c2327df5c 286 Pfam PF01590 GAF domain 36 128 1.7E-4 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS16575 5f0c76d7d51c6952c77b04166e202b18 409 SMART SM00752 17 358 2.8E-70 T 10-11-2016 IPR011020 HTTM Reactome: R-HSA-159740 A4G23_RS26250 3d7eb444def2d1ed13f7a7a0e7963f36 244 Pfam PF09844 Uncharacterized conserved protein (COG2071) 23 233 5.9E-66 T 10-11-2016 IPR018644 Protein of unknown function DUF2071 A4G23_RS26250 3d7eb444def2d1ed13f7a7a0e7963f36 244 SUPERFAMILY SSF160104 18 152 4.71E-15 T 10-11-2016 A4G23_RS26575 7f788f70b794dba5a0ab65449ee55410 507 SUPERFAMILY SSF53474 165 293 8.19E-16 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS26575 7f788f70b794dba5a0ab65449ee55410 507 SUPERFAMILY SSF53474 392 448 8.19E-16 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS26575 7f788f70b794dba5a0ab65449ee55410 507 Pfam PF07519 Tannase and feruloyl esterase 152 271 4.1E-10 T 10-11-2016 IPR011118 Tannase/feruloyl esterase MetaCyc: PWY-6784 A4G23_RS26575 7f788f70b794dba5a0ab65449ee55410 507 Gene3D G3DSA:3.40.50.1820 165 281 2.2E-17 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS26575 7f788f70b794dba5a0ab65449ee55410 507 Gene3D G3DSA:3.40.50.1820 379 445 2.2E-17 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS04875 24f537d00dea881e1a69dd16d93b2589 249 Pfam PF00293 NUDIX domain 24 132 1.4E-18 T 10-11-2016 IPR000086 NUDIX hydrolase domain GO:0016787 A4G23_RS04875 24f537d00dea881e1a69dd16d93b2589 249 Gene3D G3DSA:1.10.10.10 155 229 2.5E-25 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS04875 24f537d00dea881e1a69dd16d93b2589 249 ProSitePatterns PS00893 Nudix box signature. 54 75 - T 10-11-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A4G23_RS04875 24f537d00dea881e1a69dd16d93b2589 249 SUPERFAMILY SSF46785 162 235 3.26E-16 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS04875 24f537d00dea881e1a69dd16d93b2589 249 Gene3D G3DSA:3.90.79.10 8 149 5.1E-46 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS04875 24f537d00dea881e1a69dd16d93b2589 249 SUPERFAMILY SSF55811 16 157 6.23E-30 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS04875 24f537d00dea881e1a69dd16d93b2589 249 PRINTS PR00502 NUDIX hydrolase family signature 49 63 7.9E-5 T 10-11-2016 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A4G23_RS04875 24f537d00dea881e1a69dd16d93b2589 249 PRINTS PR00502 NUDIX hydrolase family signature 63 78 7.9E-5 T 10-11-2016 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A4G23_RS10875 d1cd0e43deb742dcb3841e5f29f3a8ab 159 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 7 153 1.4E-62 T 10-11-2016 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 A4G23_RS10875 d1cd0e43deb742dcb3841e5f29f3a8ab 159 Gene3D G3DSA:3.30.70.640 6 158 2.6E-64 T 10-11-2016 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 A4G23_RS10875 d1cd0e43deb742dcb3841e5f29f3a8ab 159 SUPERFAMILY SSF55040 14 156 6.15E-57 T 10-11-2016 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 A4G23_RS10875 d1cd0e43deb742dcb3841e5f29f3a8ab 159 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase accessory protein [moaC]. 5 159 36.065 T 10-11-2016 IPR023046 Molybdenum cofactor biosynthesis C, bacterial-type Reactome: R-HSA-947581 A4G23_RS10875 d1cd0e43deb742dcb3841e5f29f3a8ab 159 Pfam PF01967 MoaC family 18 151 1.4E-51 T 10-11-2016 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 A4G23_RS01790 6b480411a10676456213ce876d10cd35 362 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 38 321 5.7E-46 T 10-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4G23_RS01790 6b480411a10676456213ce876d10cd35 362 Gene3D G3DSA:3.40.50.1100 54 150 2.2E-23 T 10-11-2016 A4G23_RS01790 6b480411a10676456213ce876d10cd35 362 SUPERFAMILY SSF53686 30 343 2.62E-67 T 10-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4G23_RS01790 6b480411a10676456213ce876d10cd35 362 Gene3D G3DSA:3.40.50.1100 151 342 6.9E-32 T 10-11-2016 A4G23_RS20805 b1ce4e3da7052aeece159803b5e5eae1 449 Pfam PF00202 Aminotransferase class-III 39 445 1.1E-114 T 10-11-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4G23_RS20805 b1ce4e3da7052aeece159803b5e5eae1 449 Gene3D G3DSA:3.90.1150.10 324 447 1.9E-38 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS20805 b1ce4e3da7052aeece159803b5e5eae1 449 SUPERFAMILY SSF53383 36 446 4.9E-122 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS20805 b1ce4e3da7052aeece159803b5e5eae1 449 TIGRFAM TIGR00700 GABAtrnsam: 4-aminobutyrate transaminase 25 446 2.7E-173 T 10-11-2016 IPR004632 4-aminobutyrate aminotransferase, bacterial GO:0003867|GO:0009448 A4G23_RS20805 b1ce4e3da7052aeece159803b5e5eae1 449 Gene3D G3DSA:3.40.640.10 75 323 2.4E-77 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS20805 b1ce4e3da7052aeece159803b5e5eae1 449 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 256 293 - T 10-11-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4G23_RS06860 6dcc09291e027fc329652ddbc83e2de5 306 Gene3D G3DSA:1.10.3720.10 2 296 1.7E-66 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS06860 6dcc09291e027fc329652ddbc83e2de5 306 SUPERFAMILY SSF160964 7 78 1.83E-5 T 10-11-2016 A4G23_RS06860 6dcc09291e027fc329652ddbc83e2de5 306 SUPERFAMILY SSF161098 64 293 2.62E-62 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS06860 6dcc09291e027fc329652ddbc83e2de5 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 301 2.3E-22 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS25405 85c1dfcc7ba8adbde655f3975e381eff 598 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 22 183 3.3E-21 T 10-11-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS25405 85c1dfcc7ba8adbde655f3975e381eff 598 Pfam PF04542 Sigma-70 region 2 26 92 4.9E-14 T 10-11-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS25405 85c1dfcc7ba8adbde655f3975e381eff 598 SUPERFAMILY SSF88946 4 109 2.67E-22 T 10-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS25405 85c1dfcc7ba8adbde655f3975e381eff 598 Gene3D G3DSA:1.10.1740.10 5 111 2.3E-23 T 10-11-2016 A4G23_RS25405 85c1dfcc7ba8adbde655f3975e381eff 598 Gene3D G3DSA:3.40.33.10 472 562 4.2E-8 T 10-11-2016 IPR014044 CAP domain A4G23_RS25405 85c1dfcc7ba8adbde655f3975e381eff 598 Gene3D G3DSA:1.10.10.10 136 180 2.6E-5 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS25405 85c1dfcc7ba8adbde655f3975e381eff 598 Pfam PF00188 Cysteine-rich secretory protein family 480 593 2.3E-17 T 10-11-2016 IPR014044 CAP domain A4G23_RS25405 85c1dfcc7ba8adbde655f3975e381eff 598 SUPERFAMILY SSF55797 472 591 4.01E-18 T 10-11-2016 IPR014044 CAP domain A4G23_RS02765 a2dbc8ff2d542971f17af92cbd9c3be4 385 Pfam PF00480 ROK family 89 367 4.9E-31 T 10-11-2016 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A4G23_RS02765 a2dbc8ff2d542971f17af92cbd9c3be4 385 Gene3D G3DSA:1.10.10.10 11 81 1.5E-13 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS02765 a2dbc8ff2d542971f17af92cbd9c3be4 385 Gene3D G3DSA:3.30.420.40 226 351 2.5E-21 T 10-11-2016 A4G23_RS02765 a2dbc8ff2d542971f17af92cbd9c3be4 385 SUPERFAMILY SSF46785 11 72 2.58E-10 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS02765 a2dbc8ff2d542971f17af92cbd9c3be4 385 SUPERFAMILY SSF53067 86 372 5.81E-42 T 10-11-2016 A4G23_RS02765 a2dbc8ff2d542971f17af92cbd9c3be4 385 Pfam PF09339 IclR helix-turn-helix domain 20 60 2.5E-5 T 10-11-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4G23_RS02765 a2dbc8ff2d542971f17af92cbd9c3be4 385 Gene3D G3DSA:3.30.420.40 84 225 1.2E-37 T 10-11-2016 A4G23_RS04405 e8707ff72aaa7d1e627550f86a9b7197 196 TIGRFAM TIGR03847 TIGR03847: conserved hypothetical protein 5 190 1.5E-78 T 10-11-2016 IPR021441 Protein of unknown function DUF3090 A4G23_RS04405 e8707ff72aaa7d1e627550f86a9b7197 196 Pfam PF11290 Protein of unknown function (DUF3090) 7 186 3.6E-68 T 10-11-2016 IPR021441 Protein of unknown function DUF3090 A4G23_RS08965 6b8e9f31d3d617fe1c8a66a1f4f3e2a9 543 SUPERFAMILY SSF52096 28 272 2.63E-74 T 10-11-2016 IPR029045 ClpP/crotonase-like domain A4G23_RS08965 6b8e9f31d3d617fe1c8a66a1f4f3e2a9 543 SUPERFAMILY SSF52096 240 520 5.29E-87 T 10-11-2016 IPR029045 ClpP/crotonase-like domain A4G23_RS08965 6b8e9f31d3d617fe1c8a66a1f4f3e2a9 543 Pfam PF01039 Carboxyl transferase domain 51 527 3.6E-152 T 10-11-2016 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4G23_RS08965 6b8e9f31d3d617fe1c8a66a1f4f3e2a9 543 Gene3D G3DSA:3.90.226.10 283 530 3.3E-93 T 10-11-2016 IPR029045 ClpP/crotonase-like domain A4G23_RS08965 6b8e9f31d3d617fe1c8a66a1f4f3e2a9 543 Gene3D G3DSA:3.90.226.10 32 270 4.4E-80 T 10-11-2016 IPR029045 ClpP/crotonase-like domain A4G23_RS22175 e2be3ac7f4d2f529f3c82705d779a844 282 PIRSF PIRSF033887 1 282 3.3E-82 T 10-11-2016 IPR012363 Propanediol utilisation/coumermycin biosynthesis, PduX-related KEGG: 00040+2.7.1.17|KEGG: 00860+2.7.1.177|MetaCyc: PWY-5443 A4G23_RS22175 e2be3ac7f4d2f529f3c82705d779a844 282 Gene3D G3DSA:3.30.230.10 58 145 3.6E-7 T 10-11-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A4G23_RS22175 e2be3ac7f4d2f529f3c82705d779a844 282 Pfam PF00288 GHMP kinases N terminal domain 77 109 1.2E-5 T 10-11-2016 IPR006204 GHMP kinase N-terminal domain GO:0005524 A4G23_RS22175 e2be3ac7f4d2f529f3c82705d779a844 282 SUPERFAMILY SSF54211 5 144 1.06E-14 T 10-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold A4G23_RS20200 dfef1ca712c5a261764b3c11c4f993a7 535 SUPERFAMILY SSF51569 6 299 8.61E-76 T 10-11-2016 A4G23_RS20200 dfef1ca712c5a261764b3c11c4f993a7 535 SMART SM00917 382 525 3.1E-40 T 10-11-2016 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A4G23_RS20200 dfef1ca712c5a261764b3c11c4f993a7 535 Pfam PF08502 LeuA allosteric (dimerisation) domain 382 523 1.8E-27 T 10-11-2016 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A4G23_RS20200 dfef1ca712c5a261764b3c11c4f993a7 535 ProSitePatterns PS00141 Eukaryotic and viral aspartyl proteases active site. 99 110 - T 10-11-2016 IPR001969 Aspartic peptidase, active site GO:0004190|GO:0006508 A4G23_RS20200 dfef1ca712c5a261764b3c11c4f993a7 535 TIGRFAM TIGR00977 citramal_synth: citramalate synthase 12 527 2.5E-190 T 10-11-2016 IPR005675 Citramalate synthase GO:0019752|GO:0046912 KEGG: 00290+2.3.1.182|KEGG: 00660+2.3.1.182|MetaCyc: PWY-5101 A4G23_RS20200 dfef1ca712c5a261764b3c11c4f993a7 535 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 18 34 - T 10-11-2016 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A4G23_RS20200 dfef1ca712c5a261764b3c11c4f993a7 535 Gene3D G3DSA:3.20.20.70 7 356 1.7E-112 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS20200 dfef1ca712c5a261764b3c11c4f993a7 535 SUPERFAMILY SSF110921 406 520 8.63E-24 T 10-11-2016 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A4G23_RS20200 dfef1ca712c5a261764b3c11c4f993a7 535 Pfam PF00682 HMGL-like 13 276 2.5E-45 T 10-11-2016 IPR000891 Pyruvate carboxyltransferase GO:0003824 A4G23_RS06480 8eccfd672d119311572b936af79cc25b 380 SUPERFAMILY SSF53756 5 380 9.03E-77 T 10-11-2016 A4G23_RS06480 8eccfd672d119311572b936af79cc25b 380 Gene3D G3DSA:3.40.50.2000 167 360 1.3E-37 T 10-11-2016 A4G23_RS06480 8eccfd672d119311572b936af79cc25b 380 Pfam PF13439 Glycosyltransferase Family 4 16 178 1.9E-8 T 10-11-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A4G23_RS06480 8eccfd672d119311572b936af79cc25b 380 Pfam PF00534 Glycosyl transferases group 1 194 362 2.9E-43 T 10-11-2016 IPR001296 Glycosyl transferase, family 1 A4G23_RS08880 4eacb8d74b1f8a779602130da0786adb 316 ProSitePatterns PS00894 DeoR-type HTH domain signature. 7 41 - T 10-11-2016 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 A4G23_RS08880 4eacb8d74b1f8a779602130da0786adb 316 Pfam PF08279 HTH domain 7 62 5.0E-14 T 10-11-2016 IPR013196 Helix-turn-helix, type 11 A4G23_RS08880 4eacb8d74b1f8a779602130da0786adb 316 SUPERFAMILY SSF46785 4 64 6.18E-10 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS08880 4eacb8d74b1f8a779602130da0786adb 316 Pfam PF13280 WYL domain 143 312 1.0E-27 T 10-11-2016 IPR026881 WYL domain A4G23_RS08880 4eacb8d74b1f8a779602130da0786adb 316 Gene3D G3DSA:1.10.10.10 3 65 1.0E-17 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS04985 562c28e850d16cbeb2890ebd05860ae5 427 PIRSF PIRSF033563 11 425 9.0E-114 T 10-11-2016 IPR008323 Uncharacterised conserved protein UCP033563 A4G23_RS04985 562c28e850d16cbeb2890ebd05860ae5 427 Pfam PF06245 Protein of unknown function (DUF1015) 14 421 1.8E-112 T 10-11-2016 IPR008323 Uncharacterised conserved protein UCP033563 A4G23_RS08600 148193f41307b766f851a871bdfd0cff 233 Pfam PF10935 Protein of unknown function (DUF2637) 6 119 6.1E-21 T 10-11-2016 IPR021235 Protein of unknown function DUF2637 A4G23_RS14605 9e8b210d337da74dc1783d14e7e0003f 321 SMART SM00829 15 318 2.3E-21 T 10-11-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A4G23_RS14605 9e8b210d337da74dc1783d14e7e0003f 321 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 32 94 1.8E-6 T 10-11-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A4G23_RS14605 9e8b210d337da74dc1783d14e7e0003f 321 SUPERFAMILY SSF50129 3 155 1.37E-33 T 10-11-2016 IPR011032 GroES-like A4G23_RS14605 9e8b210d337da74dc1783d14e7e0003f 321 SUPERFAMILY SSF51735 126 295 4.06E-28 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS14605 9e8b210d337da74dc1783d14e7e0003f 321 Gene3D G3DSA:3.40.50.720 157 240 4.0E-15 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS14605 9e8b210d337da74dc1783d14e7e0003f 321 Pfam PF13602 Zinc-binding dehydrogenase 192 318 8.2E-24 T 10-11-2016 A4G23_RS14605 9e8b210d337da74dc1783d14e7e0003f 321 Gene3D G3DSA:3.90.180.10 5 156 3.5E-39 T 10-11-2016 IPR011032 GroES-like A4G23_RS02820 0ab95a71a4ab96e38770b31a83f00db5 1057 Gene3D G3DSA:3.40.50.300 912 1049 1.2E-32 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS02820 0ab95a71a4ab96e38770b31a83f00db5 1057 Gene3D G3DSA:3.40.50.300 2 181 1.2E-32 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS02820 0ab95a71a4ab96e38770b31a83f00db5 1057 Gene3D G3DSA:3.40.50.300 312 313 1.2E-32 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS02820 0ab95a71a4ab96e38770b31a83f00db5 1057 Pfam PF13558 Putative exonuclease SbcCD, C subunit 948 1012 5.8E-13 T 10-11-2016 A4G23_RS02820 0ab95a71a4ab96e38770b31a83f00db5 1057 SUPERFAMILY SSF52540 901 1049 1.76E-34 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS02820 0ab95a71a4ab96e38770b31a83f00db5 1057 SUPERFAMILY SSF52540 2 225 1.76E-34 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS02820 0ab95a71a4ab96e38770b31a83f00db5 1057 SUPERFAMILY SSF52540 645 685 1.76E-34 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS02820 0ab95a71a4ab96e38770b31a83f00db5 1057 Pfam PF13476 AAA domain 5 204 5.7E-21 T 10-11-2016 A4G23_RS02070 cd16e4a495d56b766d63f243ff17692b 418 Pfam PF01547 Bacterial extracellular solute-binding protein 48 332 2.1E-44 T 10-11-2016 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 A4G23_RS02070 cd16e4a495d56b766d63f243ff17692b 418 Gene3D G3DSA:3.40.190.10 168 350 1.5E-38 T 10-11-2016 A4G23_RS02070 cd16e4a495d56b766d63f243ff17692b 418 SUPERFAMILY SSF53850 22 416 9.39E-76 T 10-11-2016 A4G23_RS02070 cd16e4a495d56b766d63f243ff17692b 418 Gene3D G3DSA:3.40.190.10 49 167 6.2E-25 T 10-11-2016 A4G23_RS10685 887bc3aac43d1d92251c7246fdf59523 610 Pfam PF16192 C-terminal four TMM region of protein-O-mannosyltransferase 395 609 7.2E-21 T 10-11-2016 IPR032421 Protein O-mannosyl-transferase, C-terminal four TM domain KEGG: 00500+2.4.1.10|KEGG: 00514+2.4.1.109|MetaCyc: PWY-822|Reactome: R-HSA-5173105 A4G23_RS10685 887bc3aac43d1d92251c7246fdf59523 610 Pfam PF02366 Dolichyl-phosphate-mannose-protein mannosyltransferase 95 319 8.2E-22 T 10-11-2016 IPR003342 Glycosyl transferase family 39/83 GO:0000030|GO:0006493|GO:0016020 Reactome: R-HSA-5173105 A4G23_RS18745 a05b173fa2295c1d207baad9d9f1c5d1 135 SUPERFAMILY SSF46767 11 72 4.32E-14 T 10-11-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A4G23_RS18745 a05b173fa2295c1d207baad9d9f1c5d1 135 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 13 73 2.9E-17 T 10-11-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A4G23_RS18745 a05b173fa2295c1d207baad9d9f1c5d1 135 Gene3D G3DSA:1.10.10.10 12 71 3.9E-13 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS08080 df179730886c1a085b5088d1a5fb8943 361 Pfam PF01435 Peptidase family M48 74 268 2.1E-24 T 10-11-2016 IPR001915 Peptidase M48 GO:0004222|GO:0006508 A4G23_RS08080 df179730886c1a085b5088d1a5fb8943 361 Gene3D G3DSA:3.30.2010.10 68 154 3.3E-20 T 10-11-2016 A4G23_RS18840 608858388598da6fcc0d0259f3f3e806 369 SUPERFAMILY SSF51735 21 324 3.72E-35 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS18840 608858388598da6fcc0d0259f3f3e806 369 Gene3D G3DSA:3.40.50.720 12 235 2.3E-30 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS18840 608858388598da6fcc0d0259f3f3e806 369 Pfam PF01370 NAD dependent epimerase/dehydratase family 26 234 3.3E-19 T 10-11-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 A4G23_RS00430 0dc97ff54a460f61de64e1711c1f3f1c 597 PIRSF PIRSF001589 1 597 1.3E-209 T 10-11-2016 A4G23_RS00430 0dc97ff54a460f61de64e1711c1f3f1c 597 TIGRFAM TIGR03104 trio_amidotrans: asparagine synthase family amidotransferase 1 594 1.1E-285 T 10-11-2016 IPR017535 Asparagine synthase family amidotransferase A4G23_RS00430 0dc97ff54a460f61de64e1711c1f3f1c 597 Pfam PF13537 Glutamine amidotransferase domain 47 170 2.0E-40 T 10-11-2016 IPR017932 Glutamine amidotransferase type 2 domain A4G23_RS00430 0dc97ff54a460f61de64e1711c1f3f1c 597 Pfam PF00733 Asparagine synthase 248 592 2.6E-86 T 10-11-2016 IPR001962 Asparagine synthase GO:0004066|GO:0006529 A4G23_RS00430 0dc97ff54a460f61de64e1711c1f3f1c 597 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 525 4.2E-129 T 10-11-2016 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 A4G23_RS00430 0dc97ff54a460f61de64e1711c1f3f1c 597 SUPERFAMILY SSF52402 237 391 1.08E-76 T 10-11-2016 A4G23_RS00430 0dc97ff54a460f61de64e1711c1f3f1c 597 SUPERFAMILY SSF52402 447 573 1.08E-76 T 10-11-2016 A4G23_RS00430 0dc97ff54a460f61de64e1711c1f3f1c 597 Gene3D G3DSA:3.60.20.10 20 228 8.7E-68 T 10-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal A4G23_RS00430 0dc97ff54a460f61de64e1711c1f3f1c 597 SUPERFAMILY SSF56235 1 228 3.09E-59 T 10-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal A4G23_RS00430 0dc97ff54a460f61de64e1711c1f3f1c 597 Gene3D G3DSA:3.40.50.620 229 388 9.0E-84 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS00430 0dc97ff54a460f61de64e1711c1f3f1c 597 Gene3D G3DSA:3.40.50.620 443 592 9.0E-84 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS20425 c378ed87cab0466e7337956dbf3a1023 290 SMART SM00898 2 123 1.8E-48 T 10-11-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 A4G23_RS20425 c378ed87cab0466e7337956dbf3a1023 290 SUPERFAMILY SSF46946 139 228 1.77E-24 T 10-11-2016 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 A4G23_RS20425 c378ed87cab0466e7337956dbf3a1023 290 Pfam PF06827 Zinc finger found in FPG and IleRS 253 279 1.1E-4 T 10-11-2016 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 A4G23_RS20425 c378ed87cab0466e7337956dbf3a1023 290 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 2 121 2.6E-34 T 10-11-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 A4G23_RS20425 c378ed87cab0466e7337956dbf3a1023 290 Gene3D G3DSA:1.10.8.50 141 280 2.0E-44 T 10-11-2016 A4G23_RS20425 c378ed87cab0466e7337956dbf3a1023 290 SMART SM01232 139 231 4.3E-39 T 10-11-2016 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 A4G23_RS20425 c378ed87cab0466e7337956dbf3a1023 290 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 280 41.192 T 10-11-2016 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 A4G23_RS20425 c378ed87cab0466e7337956dbf3a1023 290 SUPERFAMILY SSF57716 231 280 3.14E-16 T 10-11-2016 A4G23_RS20425 c378ed87cab0466e7337956dbf3a1023 290 SUPERFAMILY SSF81624 2 144 7.2E-36 T 10-11-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 A4G23_RS20425 c378ed87cab0466e7337956dbf3a1023 290 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 139 226 1.5E-19 T 10-11-2016 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 A4G23_RS20425 c378ed87cab0466e7337956dbf3a1023 290 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 279 1.2E-86 T 10-11-2016 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 A4G23_RS20425 c378ed87cab0466e7337956dbf3a1023 290 ProSitePatterns PS01242 Zinc finger FPG-type signature. 255 279 - T 10-11-2016 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 A4G23_RS20425 c378ed87cab0466e7337956dbf3a1023 290 Gene3D G3DSA:3.20.190.10 2 130 8.3E-39 T 10-11-2016 A4G23_RS08400 189e6b9bb0f088f3852060031dffc059 418 Gene3D G3DSA:3.40.710.10 67 389 1.7E-79 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS08400 189e6b9bb0f088f3852060031dffc059 418 Pfam PF00144 Beta-lactamase 61 386 6.1E-63 T 10-11-2016 IPR001466 Beta-lactamase-related A4G23_RS08400 189e6b9bb0f088f3852060031dffc059 418 SUPERFAMILY SSF56601 13 257 3.86E-78 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS08400 189e6b9bb0f088f3852060031dffc059 418 SUPERFAMILY SSF56601 289 391 3.86E-78 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS06580 0cf964073fa8a45fb486a3eac2d43419 462 Gene3D G3DSA:3.30.110.40 392 460 4.5E-19 T 10-11-2016 IPR001455 TusA-like domain A4G23_RS06580 0cf964073fa8a45fb486a3eac2d43419 462 Pfam PF01206 Sulfurtransferase TusA 393 460 6.0E-14 T 10-11-2016 IPR001455 TusA-like domain A4G23_RS06580 0cf964073fa8a45fb486a3eac2d43419 462 SUPERFAMILY SSF53383 2 365 6.6E-75 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS06580 0cf964073fa8a45fb486a3eac2d43419 462 Pfam PF00266 Aminotransferase class-V 3 358 8.8E-44 T 10-11-2016 IPR000192 Aminotransferase class V domain A4G23_RS06580 0cf964073fa8a45fb486a3eac2d43419 462 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 393 417 - T 10-11-2016 IPR001455 TusA-like domain A4G23_RS06580 0cf964073fa8a45fb486a3eac2d43419 462 SUPERFAMILY SSF64307 392 460 4.71E-16 T 10-11-2016 IPR001455 TusA-like domain A4G23_RS06580 0cf964073fa8a45fb486a3eac2d43419 462 PIRSF PIRSF005572 1 373 2.8E-125 T 10-11-2016 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 A4G23_RS06580 0cf964073fa8a45fb486a3eac2d43419 462 Gene3D G3DSA:3.90.1150.10 243 363 2.5E-33 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS06580 0cf964073fa8a45fb486a3eac2d43419 462 Gene3D G3DSA:3.40.640.10 14 242 2.0E-53 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS06955 fc01515dea3715e79a388acdb3f788ba 271 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 10 270 41.923 T 10-11-2016 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A4G23_RS06955 fc01515dea3715e79a388acdb3f788ba 271 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 14 271 3.9E-91 T 10-11-2016 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A4G23_RS06955 fc01515dea3715e79a388acdb3f788ba 271 SUPERFAMILY SSF51621 9 270 2.12E-99 T 10-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A4G23_RS06955 fc01515dea3715e79a388acdb3f788ba 271 Gene3D G3DSA:3.20.20.60 8 271 2.2E-110 T 10-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A4G23_RS06955 fc01515dea3715e79a388acdb3f788ba 271 PIRSF PIRSF000388 3 271 1.4E-106 T 10-11-2016 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A4G23_RS06955 fc01515dea3715e79a388acdb3f788ba 271 Pfam PF02548 Ketopantoate hydroxymethyltransferase 9 265 4.2E-106 T 10-11-2016 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A4G23_RS26410 52a4b30060e9a6f2c10a36397a412c64 308 Pfam PF00701 Dihydrodipicolinate synthetase family 7 294 1.6E-55 T 10-11-2016 IPR002220 DapA-like GO:0008152|GO:0016829 A4G23_RS26410 52a4b30060e9a6f2c10a36397a412c64 308 SUPERFAMILY SSF51569 5 295 2.51E-82 T 10-11-2016 A4G23_RS26410 52a4b30060e9a6f2c10a36397a412c64 308 PRINTS PR00146 Dihydrodipicolinate synthase signature 41 62 4.5E-11 T 10-11-2016 IPR002220 DapA-like GO:0008152|GO:0016829 A4G23_RS26410 52a4b30060e9a6f2c10a36397a412c64 308 PRINTS PR00146 Dihydrodipicolinate synthase signature 109 125 4.5E-11 T 10-11-2016 IPR002220 DapA-like GO:0008152|GO:0016829 A4G23_RS26410 52a4b30060e9a6f2c10a36397a412c64 308 PRINTS PR00146 Dihydrodipicolinate synthase signature 134 151 4.5E-11 T 10-11-2016 IPR002220 DapA-like GO:0008152|GO:0016829 A4G23_RS26410 52a4b30060e9a6f2c10a36397a412c64 308 PRINTS PR00146 Dihydrodipicolinate synthase signature 77 95 4.5E-11 T 10-11-2016 IPR002220 DapA-like GO:0008152|GO:0016829 A4G23_RS26410 52a4b30060e9a6f2c10a36397a412c64 308 Gene3D G3DSA:3.20.20.70 6 295 5.1E-90 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS26410 52a4b30060e9a6f2c10a36397a412c64 308 SMART SM01130 6 296 1.2E-90 T 10-11-2016 IPR002220 DapA-like GO:0008152|GO:0016829 A4G23_RS26410 52a4b30060e9a6f2c10a36397a412c64 308 PIRSF PIRSF001365 2 300 1.5E-79 T 10-11-2016 IPR002220 DapA-like GO:0008152|GO:0016829 A4G23_RS18035 045578f73914e5e0310d8b9768424b33 403 SUPERFAMILY SSF53383 7 398 2.39E-96 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS18035 045578f73914e5e0310d8b9768424b33 403 Pfam PF00155 Aminotransferase class I and II 34 385 1.1E-52 T 10-11-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4G23_RS18035 045578f73914e5e0310d8b9768424b33 403 Gene3D G3DSA:3.90.1150.10 279 400 1.5E-39 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS18035 045578f73914e5e0310d8b9768424b33 403 Gene3D G3DSA:3.40.640.10 54 278 9.0E-69 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS18495 4fcc4686981be35d27ba7d7911a1f888 351 SUPERFAMILY SSF55729 245 348 2.4E-17 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS18495 4fcc4686981be35d27ba7d7911a1f888 351 Pfam PF00583 Acetyltransferase (GNAT) family 282 339 5.4E-11 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS18495 4fcc4686981be35d27ba7d7911a1f888 351 Gene3D G3DSA:3.40.630.30 257 349 1.4E-16 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS22585 6b65e4e3f5d57d4f901ea410be41e98b 244 Pfam PF04909 Amidohydrolase 4 241 8.7E-27 T 10-11-2016 IPR006680 Amidohydrolase-related GO:0016787 A4G23_RS22585 6b65e4e3f5d57d4f901ea410be41e98b 244 Gene3D G3DSA:3.20.20.140 1 243 1.7E-45 T 10-11-2016 A4G23_RS22585 6b65e4e3f5d57d4f901ea410be41e98b 244 SUPERFAMILY SSF51556 2 243 2.13E-42 T 10-11-2016 IPR032466 Metal-dependent hydrolase A4G23_RS20350 7e584f56573a81f4924c11484ab0eee8 250 Pfam PF01553 Acyltransferase 30 155 4.2E-20 T 10-11-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 A4G23_RS20350 7e584f56573a81f4924c11484ab0eee8 250 SMART SM00563 41 159 7.3E-30 T 10-11-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 A4G23_RS20350 7e584f56573a81f4924c11484ab0eee8 250 Gene3D G3DSA:3.40.1130.10 32 223 1.8E-17 T 10-11-2016 A4G23_RS20350 7e584f56573a81f4924c11484ab0eee8 250 SUPERFAMILY SSF69593 4 225 3.53E-41 T 10-11-2016 A4G23_RS25300 25c4a3867140d89e44d8596885758efe 233 Gene3D G3DSA:3.40.50.1240 2 228 6.3E-28 T 10-11-2016 IPR029033 Histidine phosphatase superfamily A4G23_RS25300 25c4a3867140d89e44d8596885758efe 233 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 75 222 1.3E-19 T 10-11-2016 IPR013078 Histidine phosphatase superfamily, clade-1 A4G23_RS25300 25c4a3867140d89e44d8596885758efe 233 SUPERFAMILY SSF53254 5 230 6.55E-33 T 10-11-2016 IPR029033 Histidine phosphatase superfamily A4G23_RS25300 25c4a3867140d89e44d8596885758efe 233 SMART SM00855 6 183 7.5E-12 T 10-11-2016 IPR013078 Histidine phosphatase superfamily, clade-1 A4G23_RS26035 3d216debbd3646bbd8f8ddd2929b7d23 309 Pfam PF13411 MerR HTH family regulatory protein 8 75 4.6E-15 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS26035 3d216debbd3646bbd8f8ddd2929b7d23 309 SMART SM00422 7 76 7.5E-24 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS26035 3d216debbd3646bbd8f8ddd2929b7d23 309 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 8 19 9.2E-11 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS26035 3d216debbd3646bbd8f8ddd2929b7d23 309 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 43 63 9.2E-11 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS26035 3d216debbd3646bbd8f8ddd2929b7d23 309 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 19 32 9.2E-11 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS26035 3d216debbd3646bbd8f8ddd2929b7d23 309 SUPERFAMILY SSF46955 7 113 1.03E-22 T 10-11-2016 IPR009061 Putative DNA-binding domain A4G23_RS26035 3d216debbd3646bbd8f8ddd2929b7d23 309 Gene3D G3DSA:1.10.1660.10 63 122 2.9E-6 T 10-11-2016 A4G23_RS26035 3d216debbd3646bbd8f8ddd2929b7d23 309 Gene3D G3DSA:1.10.1660.10 6 62 6.6E-22 T 10-11-2016 A4G23_RS22505 8880f86a511070db3c5ffb1d208fe5e3 416 Pfam PF00202 Aminotransferase class-III 32 413 5.8E-109 T 10-11-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4G23_RS22505 8880f86a511070db3c5ffb1d208fe5e3 416 Gene3D G3DSA:3.40.640.10 75 320 4.8E-81 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS22505 8880f86a511070db3c5ffb1d208fe5e3 416 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 239 276 - T 10-11-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4G23_RS22505 8880f86a511070db3c5ffb1d208fe5e3 416 SUPERFAMILY SSF53383 19 414 8.48E-114 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS22505 8880f86a511070db3c5ffb1d208fe5e3 416 Gene3D G3DSA:3.90.1150.10 324 414 2.9E-33 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS22505 8880f86a511070db3c5ffb1d208fe5e3 416 Gene3D G3DSA:3.90.1150.10 18 74 2.9E-33 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS22505 8880f86a511070db3c5ffb1d208fe5e3 416 TIGRFAM TIGR01885 Orn_aminotrans: ornithine--oxo-acid transaminase 21 413 2.3E-142 T 10-11-2016 IPR010164 Ornithine aminotransferase GO:0008483|GO:0030170 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A4G23_RS19390 3e5aa895f6d4f21fb371c8c3d543cb18 298 Pfam PF01068 ATP dependent DNA ligase domain 16 191 2.1E-24 T 10-11-2016 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 A4G23_RS19390 3e5aa895f6d4f21fb371c8c3d543cb18 298 Gene3D G3DSA:3.30.470.30 27 143 4.7E-25 T 10-11-2016 A4G23_RS19390 3e5aa895f6d4f21fb371c8c3d543cb18 298 Gene3D G3DSA:3.30.1490.70 151 192 3.7E-12 T 10-11-2016 A4G23_RS19390 3e5aa895f6d4f21fb371c8c3d543cb18 298 Gene3D G3DSA:3.30.1490.70 2 26 3.7E-12 T 10-11-2016 A4G23_RS19390 3e5aa895f6d4f21fb371c8c3d543cb18 298 SUPERFAMILY SSF56091 7 190 8.92E-41 T 10-11-2016 A4G23_RS11545 2c10fb754c19f4ea66039090788ce076 562 Pfam PF07287 Protein of unknown function (DUF1446) 8 338 8.3E-117 T 10-11-2016 IPR010839 Protein of unknown function DUF1446 A4G23_RS10045 096bf77033aca1ed8d96dae4b0a93ad0 451 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 335 420 5.0E-14 T 10-11-2016 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain A4G23_RS10045 096bf77033aca1ed8d96dae4b0a93ad0 451 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 71 224 2.3E-44 T 10-11-2016 IPR004474 Cell envelope-related transcriptional attenuator domain A4G23_RS10045 096bf77033aca1ed8d96dae4b0a93ad0 451 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 71 223 2.1E-46 T 10-11-2016 IPR004474 Cell envelope-related transcriptional attenuator domain A4G23_RS10715 172cc1b4eb8f9f46bfa8497d2ffdcdd4 191 Pfam PF16859 Bacterial transcriptional repressor C-terminal 72 183 1.4E-27 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS10715 172cc1b4eb8f9f46bfa8497d2ffdcdd4 191 SUPERFAMILY SSF46689 2 66 2.1E-12 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS10715 172cc1b4eb8f9f46bfa8497d2ffdcdd4 191 Gene3D G3DSA:1.10.10.60 3 55 1.4E-14 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS10715 172cc1b4eb8f9f46bfa8497d2ffdcdd4 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 58 1.5E-10 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS10715 172cc1b4eb8f9f46bfa8497d2ffdcdd4 191 Gene3D G3DSA:1.10.357.10 56 187 1.1E-24 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS10715 172cc1b4eb8f9f46bfa8497d2ffdcdd4 191 SUPERFAMILY SSF48498 75 186 3.11E-16 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS25075 b88895e82a228eafefaf6e91ccedbe96 415 SUPERFAMILY SSF51905 9 289 3.37E-50 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS25075 b88895e82a228eafefaf6e91ccedbe96 415 SUPERFAMILY SSF51905 370 410 3.37E-50 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS25075 b88895e82a228eafefaf6e91ccedbe96 415 Pfam PF01593 Flavin containing amine oxidoreductase 18 409 9.1E-44 T 10-11-2016 IPR002937 Amine oxidase GO:0016491|GO:0055114 A4G23_RS25075 b88895e82a228eafefaf6e91ccedbe96 415 Gene3D G3DSA:3.50.50.60 372 411 5.1E-31 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS25075 b88895e82a228eafefaf6e91ccedbe96 415 Gene3D G3DSA:3.50.50.60 208 278 5.1E-31 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS25075 b88895e82a228eafefaf6e91ccedbe96 415 Gene3D G3DSA:3.50.50.60 10 47 5.1E-31 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS05865 63601d763ae002c7b1902b20e7ad5b1b 760 Gene3D G3DSA:3.40.50.740 395 629 4.4E-51 T 10-11-2016 A4G23_RS05865 63601d763ae002c7b1902b20e7ad5b1b 760 Gene3D G3DSA:3.40.50.740 120 193 4.4E-51 T 10-11-2016 A4G23_RS05865 63601d763ae002c7b1902b20e7ad5b1b 760 TIGRFAM TIGR01701 Fdhalpha-like: oxidoreductase alpha (molybdopterin) subunit 24 756 1.8E-279 T 10-11-2016 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 A4G23_RS05865 63601d763ae002c7b1902b20e7ad5b1b 760 Pfam PF00384 Molybdopterin oxidoreductase 120 488 4.0E-29 T 10-11-2016 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS05865 63601d763ae002c7b1902b20e7ad5b1b 760 SUPERFAMILY SSF53706 58 632 1.23E-138 T 10-11-2016 A4G23_RS05865 63601d763ae002c7b1902b20e7ad5b1b 760 Gene3D G3DSA:2.40.40.20 632 756 8.6E-11 T 10-11-2016 A4G23_RS05865 63601d763ae002c7b1902b20e7ad5b1b 760 Gene3D G3DSA:3.40.228.10 194 394 7.3E-55 T 10-11-2016 A4G23_RS05865 63601d763ae002c7b1902b20e7ad5b1b 760 Pfam PF01568 Molydopterin dinucleotide binding domain 643 750 3.7E-10 T 10-11-2016 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 A4G23_RS05865 63601d763ae002c7b1902b20e7ad5b1b 760 SUPERFAMILY SSF50692 634 757 3.16E-17 T 10-11-2016 IPR009010 Aspartate decarboxylase-like domain A4G23_RS05865 63601d763ae002c7b1902b20e7ad5b1b 760 PIRSF PIRSF000144 5 760 0.0 T 10-11-2016 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 A4G23_RS20575 7ad1619fb47241358ad01bbaf92f0d64 186 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 58 4.4E-13 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS20575 7ad1619fb47241358ad01bbaf92f0d64 186 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 1.7E-8 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS20575 7ad1619fb47241358ad01bbaf92f0d64 186 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 1.7E-8 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS20575 7ad1619fb47241358ad01bbaf92f0d64 186 SUPERFAMILY SSF48498 80 185 1.29E-6 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS20575 7ad1619fb47241358ad01bbaf92f0d64 186 Gene3D G3DSA:1.10.357.10 3 185 4.2E-27 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS20575 7ad1619fb47241358ad01bbaf92f0d64 186 SUPERFAMILY SSF46689 3 74 7.98E-13 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS10950 acc2506d7b285229bf0732ac7342ef1b 454 PRINTS PR01035 Tetracycline resistance protein signature 6 22 1.2E-5 T 10-11-2016 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4G23_RS10950 acc2506d7b285229bf0732ac7342ef1b 454 PRINTS PR01035 Tetracycline resistance protein signature 121 143 1.2E-5 T 10-11-2016 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A4G23_RS10950 acc2506d7b285229bf0732ac7342ef1b 454 Gene3D G3DSA:1.20.1250.20 251 451 9.5E-16 T 10-11-2016 A4G23_RS10950 acc2506d7b285229bf0732ac7342ef1b 454 Gene3D G3DSA:1.20.1250.20 3 182 1.6E-27 T 10-11-2016 A4G23_RS10950 acc2506d7b285229bf0732ac7342ef1b 454 SUPERFAMILY SSF103473 237 449 7.19E-60 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS10950 acc2506d7b285229bf0732ac7342ef1b 454 SUPERFAMILY SSF103473 3 186 7.19E-60 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS10950 acc2506d7b285229bf0732ac7342ef1b 454 Pfam PF07690 Major Facilitator Superfamily 3 402 3.6E-48 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS25205 3e90479b26753351d2017cf851f5ca16 499 SUPERFAMILY SSF103473 466 494 4.32E-52 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS25205 3e90479b26753351d2017cf851f5ca16 499 SUPERFAMILY SSF103473 237 409 4.32E-52 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS25205 3e90479b26753351d2017cf851f5ca16 499 SUPERFAMILY SSF103473 4 190 4.32E-52 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS25205 3e90479b26753351d2017cf851f5ca16 499 Pfam PF07690 Major Facilitator Superfamily 9 400 2.7E-36 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS25205 3e90479b26753351d2017cf851f5ca16 499 Gene3D G3DSA:1.20.1250.20 256 410 7.0E-17 T 10-11-2016 A4G23_RS25205 3e90479b26753351d2017cf851f5ca16 499 Gene3D G3DSA:1.20.1250.20 8 182 1.6E-22 T 10-11-2016 A4G23_RS25205 3e90479b26753351d2017cf851f5ca16 499 Gene3D G3DSA:1.20.1250.20 468 494 7.0E-17 T 10-11-2016 A4G23_RS03730 7da80b4be2591613714342fc8ace5e50 180 SUPERFAMILY SSF53098 2 156 2.31E-45 T 10-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 A4G23_RS03730 7da80b4be2591613714342fc8ace5e50 180 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 1 155 46.626 T 10-11-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 A4G23_RS03730 7da80b4be2591613714342fc8ace5e50 180 Gene3D G3DSA:3.30.420.10 1 156 3.4E-56 T 10-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 A4G23_RS03730 7da80b4be2591613714342fc8ace5e50 180 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 3 152 1.7E-53 T 10-11-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 A4G23_RS03730 7da80b4be2591613714342fc8ace5e50 180 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 114 149 - T 10-11-2016 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 A4G23_RS03730 7da80b4be2591613714342fc8ace5e50 180 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 140 152 7.0E-36 T 10-11-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 A4G23_RS03730 7da80b4be2591613714342fc8ace5e50 180 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 84 100 7.0E-36 T 10-11-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 A4G23_RS03730 7da80b4be2591613714342fc8ace5e50 180 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 62 78 7.0E-36 T 10-11-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 A4G23_RS03730 7da80b4be2591613714342fc8ace5e50 180 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 108 127 7.0E-36 T 10-11-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 A4G23_RS03730 7da80b4be2591613714342fc8ace5e50 180 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 4 17 7.0E-36 T 10-11-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 A4G23_RS03730 7da80b4be2591613714342fc8ace5e50 180 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 3 155 6.5E-35 T 10-11-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 A4G23_RS25535 5dbd5747c6715af2a16f0b968a3b4e1a 492 SUPERFAMILY SSF51690 395 474 1.71E-9 T 10-11-2016 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 A4G23_RS25535 5dbd5747c6715af2a16f0b968a3b4e1a 492 SUPERFAMILY SSF54675 5 131 1.85E-32 T 10-11-2016 A4G23_RS25535 5dbd5747c6715af2a16f0b968a3b4e1a 492 SUPERFAMILY SSF51690 133 355 5.45E-74 T 10-11-2016 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 A4G23_RS25535 5dbd5747c6715af2a16f0b968a3b4e1a 492 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 150 214 5.5E-7 T 10-11-2016 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 A4G23_RS25535 5dbd5747c6715af2a16f0b968a3b4e1a 492 Gene3D G3DSA:3.20.140.10 4 352 2.9E-84 T 10-11-2016 A4G23_RS25535 5dbd5747c6715af2a16f0b968a3b4e1a 492 PIRSF PIRSF000484 1 478 7.6E-111 T 10-11-2016 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 A4G23_RS25535 5dbd5747c6715af2a16f0b968a3b4e1a 492 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 6 353 2.6E-120 T 10-11-2016 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 A4G23_RS15485 8b42e9b10984a9d0c15de08c93627070 467 SUPERFAMILY SSF52540 73 294 1.02E-46 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS15485 8b42e9b10984a9d0c15de08c93627070 467 SMART SM00382 91 245 4.4E-8 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS15485 8b42e9b10984a9d0c15de08c93627070 467 Gene3D G3DSA:3.40.50.300 69 276 7.3E-46 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS15485 8b42e9b10984a9d0c15de08c93627070 467 Hamap MF_01498 DNA repair protein RadA [radA]. 27 455 42.255 T 10-11-2016 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 A4G23_RS15485 8b42e9b10984a9d0c15de08c93627070 467 Pfam PF13541 Subunit ChlI of Mg-chelatase 371 430 1.7E-8 T 10-11-2016 A4G23_RS15485 8b42e9b10984a9d0c15de08c93627070 467 TIGRFAM TIGR00416 sms: DNA repair protein RadA 9 451 3.7E-152 T 10-11-2016 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 A4G23_RS15485 8b42e9b10984a9d0c15de08c93627070 467 Pfam PF13481 AAA domain 82 223 8.3E-16 T 10-11-2016 A4G23_RS15485 8b42e9b10984a9d0c15de08c93627070 467 Gene3D G3DSA:3.30.230.10 285 454 5.9E-31 T 10-11-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A4G23_RS15485 8b42e9b10984a9d0c15de08c93627070 467 SUPERFAMILY SSF54211 294 454 3.68E-34 T 10-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold A4G23_RS15485 8b42e9b10984a9d0c15de08c93627070 467 PRINTS PR01874 DNA repair protein radA signature 214 242 8.0E-86 T 10-11-2016 A4G23_RS15485 8b42e9b10984a9d0c15de08c93627070 467 PRINTS PR01874 DNA repair protein radA signature 175 199 8.0E-86 T 10-11-2016 A4G23_RS15485 8b42e9b10984a9d0c15de08c93627070 467 PRINTS PR01874 DNA repair protein radA signature 16 40 8.0E-86 T 10-11-2016 A4G23_RS15485 8b42e9b10984a9d0c15de08c93627070 467 PRINTS PR01874 DNA repair protein radA signature 249 275 8.0E-86 T 10-11-2016 A4G23_RS15485 8b42e9b10984a9d0c15de08c93627070 467 PRINTS PR01874 DNA repair protein radA signature 323 346 8.0E-86 T 10-11-2016 A4G23_RS15485 8b42e9b10984a9d0c15de08c93627070 467 PRINTS PR01874 DNA repair protein radA signature 125 142 8.0E-86 T 10-11-2016 A4G23_RS15485 8b42e9b10984a9d0c15de08c93627070 467 PRINTS PR01874 DNA repair protein radA signature 83 111 8.0E-86 T 10-11-2016 A4G23_RS02090 802219f27a5667cb5ac7d70e4ecd1842 350 SUPERFAMILY SSF52540 4 240 3.82E-76 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS02090 802219f27a5667cb5ac7d70e4ecd1842 350 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS02090 802219f27a5667cb5ac7d70e4ecd1842 350 Pfam PF00005 ABC transporter 20 164 2.5E-30 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS02090 802219f27a5667cb5ac7d70e4ecd1842 350 SUPERFAMILY SSF50331 267 341 2.55E-7 T 10-11-2016 IPR008995 Molybdate/tungstate binding, C-terminal A4G23_RS02090 802219f27a5667cb5ac7d70e4ecd1842 350 Pfam PF08402 TOBE domain 273 343 1.1E-9 T 10-11-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 A4G23_RS02090 802219f27a5667cb5ac7d70e4ecd1842 350 SMART SM00382 29 222 1.3E-16 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS02090 802219f27a5667cb5ac7d70e4ecd1842 350 Gene3D G3DSA:3.40.50.300 3 236 6.8E-72 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS09680 1ccab76988c9a1b1f5322a6e793ce31f 236 SUPERFAMILY SSF160904 113 216 1.44E-27 T 10-11-2016 A4G23_RS09680 1ccab76988c9a1b1f5322a6e793ce31f 236 Pfam PF07336 Putative stress-induced transcription regulator 23 169 1.1E-14 T 10-11-2016 IPR010852 Putative stress-induced transcription regulator A4G23_RS09680 1ccab76988c9a1b1f5322a6e793ce31f 236 Gene3D G3DSA:1.10.3300.10 7 65 1.0E-33 T 10-11-2016 IPR023286 ABATE domain A4G23_RS09680 1ccab76988c9a1b1f5322a6e793ce31f 236 Gene3D G3DSA:1.10.3300.10 106 217 1.0E-33 T 10-11-2016 IPR023286 ABATE domain A4G23_RS09680 1ccab76988c9a1b1f5322a6e793ce31f 236 Pfam PF11706 CGNR zinc finger 174 216 7.2E-16 T 10-11-2016 IPR021005 Zinc finger, CGNR A4G23_RS22035 0b2cbb011a454f01b069140fbd0fb091 118 Pfam PF03831 PhnA domain 49 118 4.4E-31 T 10-11-2016 IPR013988 PhnA protein, C-terminal A4G23_RS22035 0b2cbb011a454f01b069140fbd0fb091 118 Gene3D G3DSA:2.20.25.10 3 39 1.3E-19 T 10-11-2016 A4G23_RS22035 0b2cbb011a454f01b069140fbd0fb091 118 Gene3D G3DSA:2.30.30.40 47 118 3.9E-33 T 10-11-2016 A4G23_RS22035 0b2cbb011a454f01b069140fbd0fb091 118 Pfam PF08274 PhnA Zinc-Ribbon 5 33 1.6E-13 T 10-11-2016 IPR013987 PhnA protein, N-terminal A4G23_RS22035 0b2cbb011a454f01b069140fbd0fb091 118 SUPERFAMILY SSF57783 4 36 5.61E-13 T 10-11-2016 A4G23_RS22035 0b2cbb011a454f01b069140fbd0fb091 118 SUPERFAMILY SSF82057 46 118 2.29E-24 T 10-11-2016 A4G23_RS22035 0b2cbb011a454f01b069140fbd0fb091 118 TIGRFAM TIGR00686 phnA: putative alkylphosphonate utilization operon protein PhnA 4 118 7.2E-37 T 10-11-2016 IPR004624 PhnA protein A4G23_RS26170 739cda8674f8307bffcc305095cd80fb 316 Gene3D G3DSA:3.40.1190.20 8 285 1.0E-40 T 10-11-2016 IPR029056 Ribokinase-like A4G23_RS26170 739cda8674f8307bffcc305095cd80fb 316 SUPERFAMILY SSF53613 7 296 9.04E-43 T 10-11-2016 IPR029056 Ribokinase-like A4G23_RS26170 739cda8674f8307bffcc305095cd80fb 316 Pfam PF00294 pfkB family carbohydrate kinase 51 288 8.7E-21 T 10-11-2016 IPR011611 Carbohydrate kinase PfkB A4G23_RS26170 739cda8674f8307bffcc305095cd80fb 316 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 243 256 - T 10-11-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A4G23_RS22220 8e7a62feb5a99eea40c785146bd8a8bd 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 46 1.7E-5 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS22220 8e7a62feb5a99eea40c785146bd8a8bd 189 SUPERFAMILY SSF48498 78 183 1.11E-18 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS22220 8e7a62feb5a99eea40c785146bd8a8bd 189 Gene3D G3DSA:1.10.10.60 3 49 2.8E-13 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS22220 8e7a62feb5a99eea40c785146bd8a8bd 189 SUPERFAMILY SSF46689 8 73 1.65E-9 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS22220 8e7a62feb5a99eea40c785146bd8a8bd 189 Pfam PF13305 WHG domain 84 160 1.1E-5 T 10-11-2016 IPR025996 WHG domain A4G23_RS22220 8e7a62feb5a99eea40c785146bd8a8bd 189 Gene3D G3DSA:1.10.357.10 51 184 1.9E-37 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS09165 839fc9f576734048e7f7e4cecc030afa 282 Gene3D G3DSA:1.10.3720.10 13 267 7.0E-51 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS09165 839fc9f576734048e7f7e4cecc030afa 282 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 96 271 4.8E-18 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS09165 839fc9f576734048e7f7e4cecc030afa 282 SUPERFAMILY SSF161098 15 281 5.67E-59 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS19650 e06aaf23b792e9c0192b2035baba2f67 274 Pfam PF12730 ABC-2 family transporter protein 24 193 2.0E-8 T 10-11-2016 IPR032688 ABC-2 family transporter protein GO:0006810 A4G23_RS12770 92b88a2c9389ff7cf87775950227b91c 118 Pfam PF05239 PRC-barrel domain 7 76 1.9E-6 T 10-11-2016 IPR027275 PRC-barrel domain A4G23_RS12770 92b88a2c9389ff7cf87775950227b91c 118 SUPERFAMILY SSF50346 3 105 1.41E-15 T 10-11-2016 IPR011033 PRC-barrel-like A4G23_RS15380 cbb70670bfdec2d2427af592b620fb22 314 Gene3D G3DSA:3.40.50.620 1 155 7.9E-68 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS15380 cbb70670bfdec2d2427af592b620fb22 314 Gene3D G3DSA:3.30.1300.10 156 200 1.1E-34 T 10-11-2016 A4G23_RS15380 cbb70670bfdec2d2427af592b620fb22 314 Gene3D G3DSA:3.30.1300.10 251 311 1.1E-34 T 10-11-2016 A4G23_RS15380 cbb70670bfdec2d2427af592b620fb22 314 SUPERFAMILY SSF52374 1 202 1.84E-82 T 10-11-2016 A4G23_RS15380 cbb70670bfdec2d2427af592b620fb22 314 Pfam PF02569 Pantoate-beta-alanine ligase 1 306 3.8E-90 T 10-11-2016 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 A4G23_RS15380 cbb70670bfdec2d2427af592b620fb22 314 SUPERFAMILY SSF52374 227 310 1.26E-6 T 10-11-2016 A4G23_RS15380 cbb70670bfdec2d2427af592b620fb22 314 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 1 196 8.0E-72 T 10-11-2016 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 A4G23_RS15380 cbb70670bfdec2d2427af592b620fb22 314 Hamap MF_00158 Pantothenate synthetase [panC]. 1 308 36.316 T 10-11-2016 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 A4G23_RS12525 a7fd0d845b0fcb74c5bd437534bee8ea 376 Gene3D G3DSA:3.40.190.10 53 118 5.0E-5 T 10-11-2016 A4G23_RS12525 a7fd0d845b0fcb74c5bd437534bee8ea 376 Gene3D G3DSA:3.40.190.10 140 301 2.6E-57 T 10-11-2016 A4G23_RS12525 a7fd0d845b0fcb74c5bd437534bee8ea 376 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 59 373 3.1E-88 T 10-11-2016 IPR005673 ABC transporter, phosphate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 A4G23_RS12525 a7fd0d845b0fcb74c5bd437534bee8ea 376 Pfam PF12849 PBP superfamily domain 53 347 6.3E-64 T 10-11-2016 IPR024370 PBP domain A4G23_RS12525 a7fd0d845b0fcb74c5bd437534bee8ea 376 SUPERFAMILY SSF53850 57 376 1.09E-90 T 10-11-2016 A4G23_RS12525 a7fd0d845b0fcb74c5bd437534bee8ea 376 Gene3D G3DSA:3.40.190.10 302 370 3.1E-5 T 10-11-2016 A4G23_RS12525 a7fd0d845b0fcb74c5bd437534bee8ea 376 PIRSF PIRSF002756 11 376 2.9E-117 T 10-11-2016 IPR005673 ABC transporter, phosphate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 A4G23_RS05360 4984faf1771dfe097a6d2a84a02910fe 413 SUPERFAMILY SSF53383 5 406 3.02E-109 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS05360 4984faf1771dfe097a6d2a84a02910fe 413 TIGRFAM TIGR00709 dat: 2,4-diaminobutyrate 4-transaminase 1 409 2.0E-133 T 10-11-2016 IPR004637 2,4-diaminobutyrate 4-transaminase GO:0008483|GO:0009058 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761 A4G23_RS05360 4984faf1771dfe097a6d2a84a02910fe 413 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 226 262 - T 10-11-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4G23_RS05360 4984faf1771dfe097a6d2a84a02910fe 413 Gene3D G3DSA:3.40.640.10 49 305 2.9E-61 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS05360 4984faf1771dfe097a6d2a84a02910fe 413 Pfam PF00202 Aminotransferase class-III 14 404 1.4E-75 T 10-11-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4G23_RS05360 4984faf1771dfe097a6d2a84a02910fe 413 TIGRFAM TIGR02407 ectoine_ectB: diaminobutyrate--2-oxoglutarate aminotransferase 1 406 6.7E-199 T 10-11-2016 IPR012773 Ectoine biosynthetic protein GO:0019491|GO:0030170|GO:0047307 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761 A4G23_RS05360 4984faf1771dfe097a6d2a84a02910fe 413 Gene3D G3DSA:3.90.1150.10 8 48 8.2E-32 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS05360 4984faf1771dfe097a6d2a84a02910fe 413 Gene3D G3DSA:3.90.1150.10 311 407 8.2E-32 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS07470 a01f00c6583ff402a7084c1035134d9e 342 Pfam PF00248 Aldo/keto reductase family 26 319 3.7E-63 T 10-11-2016 IPR023210 NADP-dependent oxidoreductase domain A4G23_RS07470 a01f00c6583ff402a7084c1035134d9e 342 SUPERFAMILY SSF51430 11 322 1.17E-89 T 10-11-2016 IPR023210 NADP-dependent oxidoreductase domain A4G23_RS07470 a01f00c6583ff402a7084c1035134d9e 342 Gene3D G3DSA:3.20.20.100 10 334 2.0E-100 T 10-11-2016 IPR023210 NADP-dependent oxidoreductase domain A4G23_RS07470 a01f00c6583ff402a7084c1035134d9e 342 PRINTS PR00069 Aldo-keto reductase signature 117 135 1.4E-5 T 10-11-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4G23_RS07470 a01f00c6583ff402a7084c1035134d9e 342 PRINTS PR00069 Aldo-keto reductase signature 51 75 1.4E-5 T 10-11-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4G23_RS07470 a01f00c6583ff402a7084c1035134d9e 342 PRINTS PR00069 Aldo-keto reductase signature 148 165 1.4E-5 T 10-11-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4G23_RS24765 fec5b49dc79f8c267207e7112dd92c5e 266 SUPERFAMILY SSF55729 74 256 2.3E-16 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS24765 fec5b49dc79f8c267207e7112dd92c5e 266 Pfam PF00583 Acetyltransferase (GNAT) family 165 249 4.8E-6 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS24765 fec5b49dc79f8c267207e7112dd92c5e 266 Gene3D G3DSA:3.40.630.30 123 254 8.5E-13 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS01985 3de5f00cb5c0a9cd9054b001af1c8477 311 SUPERFAMILY SSF49785 149 297 5.1E-5 T 10-11-2016 IPR008979 Galactose-binding domain-like A4G23_RS01985 3de5f00cb5c0a9cd9054b001af1c8477 311 Gene3D G3DSA:3.30.2010.10 109 198 3.9E-9 T 10-11-2016 A4G23_RS01985 3de5f00cb5c0a9cd9054b001af1c8477 311 Pfam PF01435 Peptidase family M48 141 223 2.8E-7 T 10-11-2016 IPR001915 Peptidase M48 GO:0004222|GO:0006508 A4G23_RS08770 98a3538c08aa515dbe291d9dbceaaa44 383 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 50 135 1.1E-6 T 10-11-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 A4G23_RS08770 98a3538c08aa515dbe291d9dbceaaa44 383 Gene3D G3DSA:3.30.360.10 159 374 2.1E-36 T 10-11-2016 A4G23_RS08770 98a3538c08aa515dbe291d9dbceaaa44 383 SUPERFAMILY SSF51735 4 173 1.75E-26 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS08770 98a3538c08aa515dbe291d9dbceaaa44 383 Gene3D G3DSA:3.40.50.720 50 158 1.8E-22 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS08770 98a3538c08aa515dbe291d9dbceaaa44 383 SUPERFAMILY SSF55347 146 343 4.41E-29 T 10-11-2016 A4G23_RS20010 d901634a986fc50505d4f0176e68e3c0 275 SUPERFAMILY SSF54637 24 96 1.15E-10 T 10-11-2016 IPR029069 HotDog domain A4G23_RS20010 d901634a986fc50505d4f0176e68e3c0 275 Pfam PF13622 Thioesterase-like superfamily 26 269 1.0E-40 T 10-11-2016 A4G23_RS20010 d901634a986fc50505d4f0176e68e3c0 275 SUPERFAMILY SSF54637 128 268 6.61E-9 T 10-11-2016 IPR029069 HotDog domain A4G23_RS23985 ea77fb4c25387bc757adfab83f487372 513 SUPERFAMILY SSF56801 10 512 5.63E-140 T 10-11-2016 A4G23_RS23985 ea77fb4c25387bc757adfab83f487372 513 Gene3D G3DSA:3.40.50.980 14 164 3.3E-45 T 10-11-2016 A4G23_RS23985 ea77fb4c25387bc757adfab83f487372 513 Gene3D G3DSA:3.30.300.30 414 511 1.2E-32 T 10-11-2016 A4G23_RS23985 ea77fb4c25387bc757adfab83f487372 513 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 39 444 1.1E-121 T 10-11-2016 IPR010071 Amino acid adenylation domain A4G23_RS23985 ea77fb4c25387bc757adfab83f487372 513 Gene3D G3DSA:2.30.38.10 332 410 2.5E-24 T 10-11-2016 A4G23_RS23985 ea77fb4c25387bc757adfab83f487372 513 Pfam PF00501 AMP-binding enzyme 18 420 5.7E-87 T 10-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A4G23_RS23985 ea77fb4c25387bc757adfab83f487372 513 ProSitePatterns PS00455 Putative AMP-binding domain signature. 159 170 - T 10-11-2016 IPR020845 AMP-binding, conserved site A4G23_RS23985 ea77fb4c25387bc757adfab83f487372 513 Pfam PF13193 AMP-binding enzyme C-terminal domain 428 503 1.1E-9 T 10-11-2016 IPR025110 AMP-binding enzyme C-terminal domain A4G23_RS23985 ea77fb4c25387bc757adfab83f487372 513 Gene3D G3DSA:3.40.50.980 165 331 2.0E-33 T 10-11-2016 A4G23_RS21435 20cf4bbcc8975a8ee1c421379499544d 93 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 10-11-2016 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site A4G23_RS21435 20cf4bbcc8975a8ee1c421379499544d 93 Gene3D G3DSA:3.30.1340.10 1 88 7.5E-23 T 10-11-2016 IPR000032 Phosphocarrier protein HPr-like A4G23_RS21435 20cf4bbcc8975a8ee1c421379499544d 93 PRINTS PR00107 Phosphocarrier protein signature 13 29 9.4E-10 T 10-11-2016 IPR000032 Phosphocarrier protein HPr-like A4G23_RS21435 20cf4bbcc8975a8ee1c421379499544d 93 PRINTS PR00107 Phosphocarrier protein signature 54 71 9.4E-10 T 10-11-2016 IPR000032 Phosphocarrier protein HPr-like A4G23_RS21435 20cf4bbcc8975a8ee1c421379499544d 93 PRINTS PR00107 Phosphocarrier protein signature 39 54 9.4E-10 T 10-11-2016 IPR000032 Phosphocarrier protein HPr-like A4G23_RS21435 20cf4bbcc8975a8ee1c421379499544d 93 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 82 5.8E-24 T 10-11-2016 IPR000032 Phosphocarrier protein HPr-like A4G23_RS21435 20cf4bbcc8975a8ee1c421379499544d 93 SUPERFAMILY SSF55594 1 88 2.75E-18 T 10-11-2016 IPR000032 Phosphocarrier protein HPr-like A4G23_RS21435 20cf4bbcc8975a8ee1c421379499544d 93 Pfam PF00381 PTS HPr component phosphorylation site 3 83 2.5E-20 T 10-11-2016 IPR000032 Phosphocarrier protein HPr-like A4G23_RS15725 13467b21df0a083be35c6441be0dc49e 163 Gene3D G3DSA:1.10.1740.10 8 80 3.7E-13 T 10-11-2016 A4G23_RS15725 13467b21df0a083be35c6441be0dc49e 163 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 7 162 8.8E-53 T 10-11-2016 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 A4G23_RS15725 13467b21df0a083be35c6441be0dc49e 163 Gene3D G3DSA:1.10.10.10 106 162 3.7E-20 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS15725 13467b21df0a083be35c6441be0dc49e 163 Pfam PF04542 Sigma-70 region 2 21 80 3.9E-7 T 10-11-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS15725 13467b21df0a083be35c6441be0dc49e 163 SUPERFAMILY SSF88946 11 89 4.71E-11 T 10-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS15725 13467b21df0a083be35c6441be0dc49e 163 Pfam PF08281 Sigma-70, region 4 108 160 6.4E-17 T 10-11-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS15725 13467b21df0a083be35c6441be0dc49e 163 SUPERFAMILY SSF88659 103 162 1.44E-16 T 10-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS15725 13467b21df0a083be35c6441be0dc49e 163 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 12 161 1.3E-19 T 10-11-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS21785 63e17f739be5ebf804fcbb6b0262c5b7 69 Pfam PF03621 MbtH-like protein 1 52 1.8E-26 T 10-11-2016 IPR005153 MbtH-like protein A4G23_RS21785 63e17f739be5ebf804fcbb6b0262c5b7 69 SMART SM00923 3 53 1.9E-27 T 10-11-2016 IPR005153 MbtH-like protein A4G23_RS21785 63e17f739be5ebf804fcbb6b0262c5b7 69 SUPERFAMILY SSF160582 1 68 2.48E-29 T 10-11-2016 A4G23_RS21785 63e17f739be5ebf804fcbb6b0262c5b7 69 Gene3D G3DSA:3.90.820.10 11 68 5.6E-29 T 10-11-2016 A4G23_RS23265 3ea7bc640316d339d57a9d253e4d88a2 313 Gene3D G3DSA:3.40.50.300 23 243 1.7E-63 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS23265 3ea7bc640316d339d57a9d253e4d88a2 313 SUPERFAMILY SSF52540 22 243 1.52E-63 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS23265 3ea7bc640316d339d57a9d253e4d88a2 313 Pfam PF00005 ABC transporter 42 193 1.9E-30 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS23265 3ea7bc640316d339d57a9d253e4d88a2 313 SMART SM00382 51 242 2.4E-14 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS23265 3ea7bc640316d339d57a9d253e4d88a2 313 ProSitePatterns PS00211 ABC transporters family signature. 166 180 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS11310 2401fec0abc4942767ff8b43222a2175 197 Pfam PF04542 Sigma-70 region 2 40 104 9.2E-14 T 10-11-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS11310 2401fec0abc4942767ff8b43222a2175 197 SUPERFAMILY SSF88946 15 116 5.49E-23 T 10-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS11310 2401fec0abc4942767ff8b43222a2175 197 SUPERFAMILY SSF88659 133 191 2.8E-13 T 10-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS11310 2401fec0abc4942767ff8b43222a2175 197 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 60 91 - T 10-11-2016 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS11310 2401fec0abc4942767ff8b43222a2175 197 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 34 188 4.6E-22 T 10-11-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS11310 2401fec0abc4942767ff8b43222a2175 197 Gene3D G3DSA:1.10.1740.10 15 122 1.2E-23 T 10-11-2016 A4G23_RS11310 2401fec0abc4942767ff8b43222a2175 197 Gene3D G3DSA:1.10.10.10 135 191 1.0E-17 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS11310 2401fec0abc4942767ff8b43222a2175 197 Pfam PF08281 Sigma-70, region 4 135 186 1.3E-13 T 10-11-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS03420 f32f5d293237700b7b5d8e1be115af37 265 Pfam PF00795 Carbon-nitrogen hydrolase 5 243 4.6E-46 T 10-11-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 A4G23_RS03420 f32f5d293237700b7b5d8e1be115af37 265 Gene3D G3DSA:3.60.110.10 2 264 3.1E-76 T 10-11-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 A4G23_RS03420 f32f5d293237700b7b5d8e1be115af37 265 SUPERFAMILY SSF56317 1 263 2.35E-72 T 10-11-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 A4G23_RS03420 f32f5d293237700b7b5d8e1be115af37 265 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 143 163 - T 10-11-2016 IPR001110 Uncharacterised protein family UPF0012, conserved site A4G23_RS09155 3f2513a643935a8f4d0e5eaa131711d7 453 Gene3D G3DSA:3.40.190.10 66 187 3.3E-9 T 10-11-2016 A4G23_RS09155 3f2513a643935a8f4d0e5eaa131711d7 453 SUPERFAMILY SSF53850 51 449 3.57E-45 T 10-11-2016 A4G23_RS09155 3f2513a643935a8f4d0e5eaa131711d7 453 Gene3D G3DSA:3.40.190.10 188 379 2.4E-21 T 10-11-2016 A4G23_RS09155 3f2513a643935a8f4d0e5eaa131711d7 453 Pfam PF13416 Bacterial extracellular solute-binding protein 73 384 1.0E-27 T 10-11-2016 A4G23_RS14260 88749acbba208b189523db9516637f13 217 Gene3D G3DSA:3.40.50.2300 2 160 1.6E-39 T 10-11-2016 A4G23_RS14260 88749acbba208b189523db9516637f13 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 2.2E-13 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS14260 88749acbba208b189523db9516637f13 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 2.2E-13 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS14260 88749acbba208b189523db9516637f13 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 2.2E-13 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS14260 88749acbba208b189523db9516637f13 217 SMART SM00448 5 118 5.0E-31 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS14260 88749acbba208b189523db9516637f13 217 SUPERFAMILY SSF46894 148 216 1.33E-20 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS14260 88749acbba208b189523db9516637f13 217 SMART SM00421 152 209 3.9E-22 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS14260 88749acbba208b189523db9516637f13 217 Pfam PF00072 Response regulator receiver domain 7 118 6.5E-29 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS14260 88749acbba208b189523db9516637f13 217 ProSitePatterns PS00622 LuxR-type HTH domain signature. 169 196 - T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS14260 88749acbba208b189523db9516637f13 217 SUPERFAMILY SSF52172 4 130 8.82E-35 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS14260 88749acbba208b189523db9516637f13 217 Gene3D G3DSA:1.10.10.10 161 216 3.2E-23 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS14260 88749acbba208b189523db9516637f13 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 209 7.5E-17 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS18295 c864fcfd34eb3b22108c06fed4bd2b63 196 Pfam PF00881 Nitroreductase family 16 173 8.3E-18 T 10-11-2016 IPR029479 Nitroreductase Reactome: R-HSA-209968 A4G23_RS18295 c864fcfd34eb3b22108c06fed4bd2b63 196 Gene3D G3DSA:3.40.109.10 13 194 1.1E-38 T 10-11-2016 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4G23_RS18295 c864fcfd34eb3b22108c06fed4bd2b63 196 SUPERFAMILY SSF55469 13 195 4.45E-39 T 10-11-2016 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4G23_RS01520 d85d23051ecd5ccdea14baf6977da637 120 SUPERFAMILY SSF142906 1 113 4.58E-20 T 10-11-2016 A4G23_RS01520 d85d23051ecd5ccdea14baf6977da637 120 Pfam PF04237 YjbR 12 99 6.7E-16 T 10-11-2016 IPR007351 Uncharacterised protein YjbR A4G23_RS17005 f0013c5a7682fb9515b68a36bf19b6dd 569 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 23 46 - T 10-11-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 A4G23_RS17005 f0013c5a7682fb9515b68a36bf19b6dd 569 Gene3D G3DSA:1.10.510.10 87 271 1.4E-45 T 10-11-2016 A4G23_RS17005 f0013c5a7682fb9515b68a36bf19b6dd 569 SUPERFAMILY SSF56112 13 274 3.94E-66 T 10-11-2016 IPR011009 Protein kinase-like domain A4G23_RS17005 f0013c5a7682fb9515b68a36bf19b6dd 569 Gene3D G3DSA:3.30.200.20 12 86 7.1E-24 T 10-11-2016 A4G23_RS17005 f0013c5a7682fb9515b68a36bf19b6dd 569 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 142 154 - T 10-11-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 A4G23_RS17005 f0013c5a7682fb9515b68a36bf19b6dd 569 SMART SM00220 17 277 3.4E-58 T 10-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4G23_RS17005 f0013c5a7682fb9515b68a36bf19b6dd 569 Pfam PF00069 Protein kinase domain 17 269 2.3E-45 T 10-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4G23_RS01080 4c9174285f8b12625b1824a75a4ba659 467 Pfam PF00294 pfkB family carbohydrate kinase 171 295 5.8E-17 T 10-11-2016 IPR011611 Carbohydrate kinase PfkB A4G23_RS01080 4c9174285f8b12625b1824a75a4ba659 467 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 328 387 6.7E-13 T 10-11-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A4G23_RS01080 4c9174285f8b12625b1824a75a4ba659 467 SUPERFAMILY SSF53613 7 299 2.65E-32 T 10-11-2016 IPR029056 Ribokinase-like A4G23_RS01080 4c9174285f8b12625b1824a75a4ba659 467 Pfam PF01467 Cytidylyltransferase-like 331 422 4.8E-14 T 10-11-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A4G23_RS01080 4c9174285f8b12625b1824a75a4ba659 467 Gene3D G3DSA:3.40.1190.20 6 291 1.7E-38 T 10-11-2016 IPR029056 Ribokinase-like A4G23_RS01080 4c9174285f8b12625b1824a75a4ba659 467 Gene3D G3DSA:3.40.50.620 327 446 7.0E-31 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS01080 4c9174285f8b12625b1824a75a4ba659 467 SUPERFAMILY SSF52374 329 458 3.1E-20 T 10-11-2016 A4G23_RS19240 f72cf3d0ce74505a59905a746114f7d8 166 Pfam PF08974 Domain of unknown function (DUF1877) 1 163 1.0E-40 T 10-11-2016 IPR015068 Protein of unknown function DUF1877 A4G23_RS19240 f72cf3d0ce74505a59905a746114f7d8 166 SUPERFAMILY SSF111069 3 164 1.57E-19 T 10-11-2016 IPR015068 Protein of unknown function DUF1877 A4G23_RS19240 f72cf3d0ce74505a59905a746114f7d8 166 Gene3D G3DSA:3.40.1760.10 1 164 7.9E-27 T 10-11-2016 IPR015068 Protein of unknown function DUF1877 A4G23_RS00980 1fa8550011b1252a01046bec60e49411 140 Gene3D G3DSA:2.40.50.140 3 70 1.0E-17 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS00980 1fa8550011b1252a01046bec60e49411 140 PRINTS PR00050 Cold shock protein signature 5 20 2.0E-5 T 10-11-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4G23_RS00980 1fa8550011b1252a01046bec60e49411 140 PRINTS PR00050 Cold shock protein signature 26 35 2.0E-5 T 10-11-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4G23_RS00980 1fa8550011b1252a01046bec60e49411 140 PRINTS PR00050 Cold shock protein signature 40 58 2.0E-5 T 10-11-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4G23_RS00980 1fa8550011b1252a01046bec60e49411 140 SUPERFAMILY SSF50249 2 67 2.29E-15 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS00980 1fa8550011b1252a01046bec60e49411 140 SMART SM00357 4 67 6.6E-9 T 10-11-2016 IPR011129 Cold shock protein GO:0003676 A4G23_RS00980 1fa8550011b1252a01046bec60e49411 140 Pfam PF00313 'Cold-shock' DNA-binding domain 4 65 1.9E-13 T 10-11-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4G23_RS10700 cd6654bfb4c6429192c53bc18e8c9b99 391 SUPERFAMILY SSF56601 8 386 1.15E-69 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS10700 cd6654bfb4c6429192c53bc18e8c9b99 391 Pfam PF00144 Beta-lactamase 19 382 2.7E-71 T 10-11-2016 IPR001466 Beta-lactamase-related A4G23_RS10700 cd6654bfb4c6429192c53bc18e8c9b99 391 Gene3D G3DSA:3.40.710.10 7 218 4.3E-80 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS10700 cd6654bfb4c6429192c53bc18e8c9b99 391 Gene3D G3DSA:3.40.710.10 252 388 4.3E-80 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS25275 a9aef10782d320f065422d68d29a7316 416 Gene3D G3DSA:3.40.640.10 59 273 7.8E-23 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS25275 a9aef10782d320f065422d68d29a7316 416 SUPERFAMILY SSF53383 21 371 1.95E-52 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS25275 a9aef10782d320f065422d68d29a7316 416 Gene3D G3DSA:3.90.1150.10 280 369 6.4E-11 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS25275 a9aef10782d320f065422d68d29a7316 416 Gene3D G3DSA:3.90.1150.10 18 58 6.4E-11 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS25275 a9aef10782d320f065422d68d29a7316 416 Pfam PF00202 Aminotransferase class-III 17 131 3.5E-9 T 10-11-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4G23_RS25275 a9aef10782d320f065422d68d29a7316 416 Pfam PF00202 Aminotransferase class-III 167 342 5.7E-15 T 10-11-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4G23_RS21235 99e40d09ef0aa4743d963c78a422d53e 93 Pfam PF14013 MT0933-like antitoxin protein 16 62 4.3E-16 T 10-11-2016 IPR028037 Antitoxin Rv0909/MT0933 A4G23_RS04400 333c7c48e183c02896c84664ea8119e1 277 TIGRFAM TIGR03843 TIGR03843: conserved hypothetical protein 22 277 6.9E-106 T 10-11-2016 IPR022292 Conserved hypothetical protein CHP03843 A4G23_RS07170 8db28a9235964b273c8f73433ba51b00 448 Pfam PF13439 Glycosyltransferase Family 4 36 247 1.6E-26 T 10-11-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A4G23_RS07170 8db28a9235964b273c8f73433ba51b00 448 SUPERFAMILY SSF53756 24 442 3.86E-78 T 10-11-2016 A4G23_RS07170 8db28a9235964b273c8f73433ba51b00 448 Pfam PF00534 Glycosyl transferases group 1 261 418 6.6E-26 T 10-11-2016 IPR001296 Glycosyl transferase, family 1 A4G23_RS07170 8db28a9235964b273c8f73433ba51b00 448 Gene3D G3DSA:3.40.50.2000 228 418 1.7E-26 T 10-11-2016 A4G23_RS20640 3faf8e58adf72eaa4f896a8fce6e0972 242 SUPERFAMILY SSF52540 9 231 1.09E-50 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS20640 3faf8e58adf72eaa4f896a8fce6e0972 242 Pfam PF00005 ABC transporter 27 174 6.9E-25 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS20640 3faf8e58adf72eaa4f896a8fce6e0972 242 Gene3D G3DSA:3.40.50.300 9 226 7.9E-54 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS20640 3faf8e58adf72eaa4f896a8fce6e0972 242 SMART SM00382 34 222 9.6E-17 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS09415 0567fdb899921db08403cbb5378ce395 125 Gene3D G3DSA:3.40.50.720 49 124 4.1E-4 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS01695 ad10088c9091b4a5202861a834acc0c6 308 Pfam PF04203 Sortase family 140 270 1.2E-11 T 10-11-2016 IPR005754 Sortase family A4G23_RS01695 ad10088c9091b4a5202861a834acc0c6 308 SUPERFAMILY SSF63817 132 269 1.83E-12 T 10-11-2016 IPR023365 Sortase domain A4G23_RS01695 ad10088c9091b4a5202861a834acc0c6 308 Gene3D G3DSA:2.40.260.10 182 268 8.9E-10 T 10-11-2016 IPR023365 Sortase domain A4G23_RS13745 37028c1dcd21c097a7ef973ab24e7665 303 SMART SM00422 14 82 1.2E-11 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS13745 37028c1dcd21c097a7ef973ab24e7665 303 Gene3D G3DSA:1.10.1660.10 14 109 5.8E-20 T 10-11-2016 A4G23_RS13745 37028c1dcd21c097a7ef973ab24e7665 303 Pfam PF13411 MerR HTH family regulatory protein 14 81 5.6E-17 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS13745 37028c1dcd21c097a7ef973ab24e7665 303 SUPERFAMILY SSF46955 14 85 2.01E-17 T 10-11-2016 IPR009061 Putative DNA-binding domain A4G23_RS24380 cf47f28450ab6c3b1eac3550beb9aa50 246 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 72 2.1E-17 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS24380 cf47f28450ab6c3b1eac3550beb9aa50 246 SUPERFAMILY SSF46785 8 76 6.13E-19 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS24380 cf47f28450ab6c3b1eac3550beb9aa50 246 Gene3D G3DSA:3.40.1410.10 100 226 1.4E-6 T 10-11-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain A4G23_RS24380 cf47f28450ab6c3b1eac3550beb9aa50 246 SMART SM00345 13 72 9.7E-19 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS24380 cf47f28450ab6c3b1eac3550beb9aa50 246 SUPERFAMILY SSF64288 60 234 6.75E-13 T 10-11-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain A4G23_RS24380 cf47f28450ab6c3b1eac3550beb9aa50 246 Gene3D G3DSA:1.10.10.10 9 77 7.4E-21 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS24380 cf47f28450ab6c3b1eac3550beb9aa50 246 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 32 46 5.1E-9 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS24380 cf47f28450ab6c3b1eac3550beb9aa50 246 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 62 5.1E-9 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS00270 6e26ade0ef5e74b86b98d64c2cbbeb94 499 Gene3D G3DSA:3.40.50.270 332 482 3.2E-24 T 10-11-2016 A4G23_RS00270 6e26ade0ef5e74b86b98d64c2cbbeb94 499 SUPERFAMILY SSF52788 332 481 4.32E-20 T 10-11-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily A4G23_RS00270 6e26ade0ef5e74b86b98d64c2cbbeb94 499 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 333 480 1.2E-11 T 10-11-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily A4G23_RS00270 6e26ade0ef5e74b86b98d64c2cbbeb94 499 SMART SM00226 331 486 1.1E-5 T 10-11-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily A4G23_RS22030 99713a6aa400b2cb9ab49dfc3095edea 1606 Gene3D G3DSA:3.40.50.300 1238 1365 1.9E-11 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS22030 99713a6aa400b2cb9ab49dfc3095edea 1606 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 1237 1285 2.4E-4 T 10-11-2016 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 A4G23_RS22030 99713a6aa400b2cb9ab49dfc3095edea 1606 SUPERFAMILY SSF52540 1244 1386 2.9E-13 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS22030 99713a6aa400b2cb9ab49dfc3095edea 1606 Pfam PF12458 ATPase involved in DNA repair 28 471 2.9E-158 T 10-11-2016 IPR020958 DUF3686 A4G23_RS12755 0d7e2f7601cdd5f942aa477f7045c44e 427 Pfam PF13367 Protease prsW family 90 286 7.1E-49 T 10-11-2016 IPR026898 Protease PrsW GO:0008233 A4G23_RS18220 ffc7664b9be796eca5aa26cc9da41546 295 SUPERFAMILY SSF117892 102 229 2.48E-8 T 10-11-2016 IPR001107 Band 7 domain A4G23_RS18220 ffc7664b9be796eca5aa26cc9da41546 295 Pfam PF01145 SPFH domain / Band 7 family 67 240 3.4E-24 T 10-11-2016 IPR001107 Band 7 domain A4G23_RS18220 ffc7664b9be796eca5aa26cc9da41546 295 SMART SM00244 63 227 1.7E-8 T 10-11-2016 IPR001107 Band 7 domain A4G23_RS15960 04663841b0ae39d6965b87dd420adf62 112 Pfam PF13560 Helix-turn-helix domain 38 95 9.2E-11 T 10-11-2016 A4G23_RS15960 04663841b0ae39d6965b87dd420adf62 112 SMART SM00530 41 96 2.8E-7 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS15960 04663841b0ae39d6965b87dd420adf62 112 SUPERFAMILY SSF47413 35 103 2.6E-14 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS15960 04663841b0ae39d6965b87dd420adf62 112 Gene3D G3DSA:1.10.260.40 35 103 2.3E-15 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS24840 45ffbe4cd9970b71419ca016f71b1e7b 197 Pfam PF00293 NUDIX domain 47 176 3.8E-24 T 10-11-2016 IPR000086 NUDIX hydrolase domain GO:0016787 A4G23_RS24840 45ffbe4cd9970b71419ca016f71b1e7b 197 Gene3D G3DSA:3.90.79.10 21 183 5.3E-49 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS24840 45ffbe4cd9970b71419ca016f71b1e7b 197 SUPERFAMILY SSF55811 22 182 5.28E-44 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS24840 45ffbe4cd9970b71419ca016f71b1e7b 197 PIRSF PIRSF018427 3 194 3.7E-53 T 10-11-2016 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 A4G23_RS24840 45ffbe4cd9970b71419ca016f71b1e7b 197 TIGRFAM TIGR02150 IPP_isom_1: isopentenyl-diphosphate delta-isomerase 24 179 2.2E-35 T 10-11-2016 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 A4G23_RS24840 45ffbe4cd9970b71419ca016f71b1e7b 197 Hamap MF_00202 Isopentenyl-diphosphate Delta-isomerase [idi]. 20 191 32.318 T 10-11-2016 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 A4G23_RS24615 ad4c17e413077f99204235feff0a7a4a 236 SUPERFAMILY SSF81923 100 233 3.43E-21 T 10-11-2016 IPR004176 Clp, N-terminal GO:0019538 A4G23_RS24615 ad4c17e413077f99204235feff0a7a4a 236 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 188 232 1.3E-8 T 10-11-2016 IPR004176 Clp, N-terminal GO:0019538 A4G23_RS24615 ad4c17e413077f99204235feff0a7a4a 236 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 113 163 9.8E-10 T 10-11-2016 IPR004176 Clp, N-terminal GO:0019538 A4G23_RS24615 ad4c17e413077f99204235feff0a7a4a 236 Gene3D G3DSA:1.10.1780.10 98 233 1.1E-30 T 10-11-2016 IPR004176 Clp, N-terminal GO:0019538 A4G23_RS07975 71feff6a078cc5747677e8cfc7f310a5 247 SMART SM00849 3 199 0.0011 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS07975 71feff6a078cc5747677e8cfc7f310a5 247 SUPERFAMILY SSF56281 2 236 6.94E-34 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS07975 71feff6a078cc5747677e8cfc7f310a5 247 Gene3D G3DSA:3.60.15.10 1 241 6.5E-22 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS07975 71feff6a078cc5747677e8cfc7f310a5 247 Pfam PF00753 Metallo-beta-lactamase superfamily 3 67 5.5E-9 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS19745 3176014cf41179ec5af7ac4d26dd12af 162 SUPERFAMILY SSF55729 1 148 1.18E-27 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS19745 3176014cf41179ec5af7ac4d26dd12af 162 Pfam PF00583 Acetyltransferase (GNAT) family 58 136 1.0E-11 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS19745 3176014cf41179ec5af7ac4d26dd12af 162 Gene3D G3DSA:3.40.630.30 1 147 1.6E-31 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS26650 c231a2581f1c73622266cf8d9cc4371f 260 Gene3D G3DSA:2.30.320.10 32 132 1.6E-12 T 10-11-2016 IPR015315 Protein of unknown function DUF1963 A4G23_RS26650 c231a2581f1c73622266cf8d9cc4371f 260 SUPERFAMILY SSF103032 32 256 9.15E-17 T 10-11-2016 IPR015315 Protein of unknown function DUF1963 A4G23_RS26650 c231a2581f1c73622266cf8d9cc4371f 260 Pfam PF09234 Domain of unknown function (DUF1963) 57 254 3.2E-16 T 10-11-2016 IPR015315 Protein of unknown function DUF1963 A4G23_RS13970 5a16a0183c968ee0c09588df4ac98685 174 TIGRFAM TIGR03941 tRNA_deam_assoc: putative tRNA adenosine deaminase-associated protein 2 172 4.7E-27 T 10-11-2016 IPR023869 tRNA adenosine deaminase-associated protein, putative A4G23_RS05395 e1d52f2d6d695bc161330314c6821ac6 158 Pfam PF13302 Acetyltransferase (GNAT) domain 8 134 4.4E-18 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS05395 e1d52f2d6d695bc161330314c6821ac6 158 Gene3D G3DSA:3.40.630.30 5 156 6.3E-26 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS05395 e1d52f2d6d695bc161330314c6821ac6 158 SUPERFAMILY SSF55729 6 155 6.31E-26 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS17970 e6cdbf29f73efb4902261b9e5ccbfb4f 133 Pfam PF14155 Domain of unknown function (DUF4307) 22 130 7.7E-33 T 10-11-2016 IPR025443 Protein of unknown function DUF4307 A4G23_RS15640 8a857e4784b02f848c4108b7fe838ec5 144 SUPERFAMILY SSF46785 12 141 4.95E-25 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS15640 8a857e4784b02f848c4108b7fe838ec5 144 Pfam PF01047 MarR family 42 96 1.6E-12 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS15640 8a857e4784b02f848c4108b7fe838ec5 144 Gene3D G3DSA:1.10.10.10 7 141 6.3E-29 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS15640 8a857e4784b02f848c4108b7fe838ec5 144 ProSitePatterns PS01117 MarR-type HTH domain signature. 71 105 - T 10-11-2016 IPR023187 Transcriptional regulator MarR-type, conserved site A4G23_RS15640 8a857e4784b02f848c4108b7fe838ec5 144 SMART SM00347 34 130 3.4E-13 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS10335 16e5f879af95848fae6ca2c6cd59e64c 843 Pfam PF02687 FtsX-like permease family 719 835 1.8E-21 T 10-11-2016 IPR003838 ABC transporter permease protein domain GO:0016020 A4G23_RS10335 16e5f879af95848fae6ca2c6cd59e64c 843 Pfam PF02687 FtsX-like permease family 269 389 2.9E-23 T 10-11-2016 IPR003838 ABC transporter permease protein domain GO:0016020 A4G23_RS10335 16e5f879af95848fae6ca2c6cd59e64c 843 Pfam PF12704 MacB-like periplasmic core domain 491 679 2.1E-8 T 10-11-2016 IPR025857 MacB-like periplasmic core domain A4G23_RS10335 16e5f879af95848fae6ca2c6cd59e64c 843 Pfam PF12704 MacB-like periplasmic core domain 17 232 1.7E-16 T 10-11-2016 IPR025857 MacB-like periplasmic core domain A4G23_RS22660 e23d6c7ac22aaad59b1668e72308ec77 122 PIRSF PIRSF029826 1 119 5.6E-40 T 10-11-2016 IPR011394 NTP Pyrophosphohydrolase MazG-related, RS21-C6 A4G23_RS22660 e23d6c7ac22aaad59b1668e72308ec77 122 Gene3D G3DSA:1.10.287.1080 5 98 1.8E-21 T 10-11-2016 A4G23_RS22660 e23d6c7ac22aaad59b1668e72308ec77 122 SUPERFAMILY SSF101386 7 113 1.89E-32 T 10-11-2016 A4G23_RS22660 e23d6c7ac22aaad59b1668e72308ec77 122 Pfam PF12643 MazG-like family 35 106 5.4E-13 T 10-11-2016 IPR025984 MazG-like domain KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 A4G23_RS21000 c09eeac31ad1fb210f12f4ecacf4a237 459 SUPERFAMILY SSF63411 264 450 3.51E-48 T 10-11-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A4G23_RS21000 c09eeac31ad1fb210f12f4ecacf4a237 459 Pfam PF00675 Insulinase (Peptidase family M16) 45 192 5.8E-37 T 10-11-2016 IPR011765 Peptidase M16, N-terminal A4G23_RS21000 c09eeac31ad1fb210f12f4ecacf4a237 459 SUPERFAMILY SSF63411 34 238 7.88E-61 T 10-11-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A4G23_RS21000 c09eeac31ad1fb210f12f4ecacf4a237 459 Gene3D G3DSA:3.30.830.10 263 448 4.0E-57 T 10-11-2016 IPR011237 Peptidase M16 domain GO:0046872 A4G23_RS21000 c09eeac31ad1fb210f12f4ecacf4a237 459 Pfam PF05193 Peptidase M16 inactive domain 199 380 6.6E-43 T 10-11-2016 IPR007863 Peptidase M16, C-terminal A4G23_RS21000 c09eeac31ad1fb210f12f4ecacf4a237 459 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 66 89 - T 10-11-2016 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 A4G23_RS21000 c09eeac31ad1fb210f12f4ecacf4a237 459 Gene3D G3DSA:3.30.830.10 35 240 3.9E-58 T 10-11-2016 IPR011237 Peptidase M16 domain GO:0046872 A4G23_RS12255 4385c4d5a40bddd8db37a9b22e37fdad 448 SUPERFAMILY SSF53756 47 437 7.22E-85 T 10-11-2016 A4G23_RS12255 4385c4d5a40bddd8db37a9b22e37fdad 448 TIGRFAM TIGR03449 mycothiol_MshA: D-inositol-3-phosphate glycosyltransferase 30 437 7.0E-200 T 10-11-2016 IPR017814 Mycothiol biosynthesis protein, MshA GO:0008375|GO:0010125 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 A4G23_RS12255 4385c4d5a40bddd8db37a9b22e37fdad 448 Hamap MF_01695 D-inositol-3-phosphate glycosyltransferase [mshA]. 29 440 51.583 T 10-11-2016 IPR017814 Mycothiol biosynthesis protein, MshA GO:0008375|GO:0010125 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 A4G23_RS12255 4385c4d5a40bddd8db37a9b22e37fdad 448 Gene3D G3DSA:3.40.50.2000 210 414 4.6E-42 T 10-11-2016 A4G23_RS12255 4385c4d5a40bddd8db37a9b22e37fdad 448 Pfam PF13439 Glycosyltransferase Family 4 49 230 5.9E-32 T 10-11-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A4G23_RS12255 4385c4d5a40bddd8db37a9b22e37fdad 448 Pfam PF00534 Glycosyl transferases group 1 241 413 4.6E-32 T 10-11-2016 IPR001296 Glycosyl transferase, family 1 A4G23_RS16220 4397bf3f5d17b46170d542e05c7f403e 663 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 425 447 5.4E-6 T 10-11-2016 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 A4G23_RS16220 4397bf3f5d17b46170d542e05c7f403e 663 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 261 283 5.4E-6 T 10-11-2016 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 A4G23_RS16220 4397bf3f5d17b46170d542e05c7f403e 663 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 83 103 5.4E-6 T 10-11-2016 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 A4G23_RS16220 4397bf3f5d17b46170d542e05c7f403e 663 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 68 119 1.7E-10 T 10-11-2016 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16220 4397bf3f5d17b46170d542e05c7f403e 663 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 6 486 3.1E-129 T 10-11-2016 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16220 4397bf3f5d17b46170d542e05c7f403e 663 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 243 269 3.9E-48 T 10-11-2016 A4G23_RS16220 4397bf3f5d17b46170d542e05c7f403e 663 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 81 106 3.9E-48 T 10-11-2016 A4G23_RS16220 4397bf3f5d17b46170d542e05c7f403e 663 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 109 129 3.9E-48 T 10-11-2016 A4G23_RS16220 4397bf3f5d17b46170d542e05c7f403e 663 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 426 445 3.9E-48 T 10-11-2016 A4G23_RS16220 4397bf3f5d17b46170d542e05c7f403e 663 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 156 177 3.9E-48 T 10-11-2016 A4G23_RS16220 4397bf3f5d17b46170d542e05c7f403e 663 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 221 242 3.9E-48 T 10-11-2016 A4G23_RS16220 4397bf3f5d17b46170d542e05c7f403e 663 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 311 323 3.9E-48 T 10-11-2016 A4G23_RS16220 4397bf3f5d17b46170d542e05c7f403e 663 Pfam PF00361 Proton-conducting membrane transporter 132 403 3.6E-73 T 10-11-2016 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS13990 498a827f16bb63663ecf9660f7662c7e 98 PIRSF PIRSF006909 1 98 1.6E-58 T 10-11-2016 IPR014447 Uncharacterised conserved protein UCP006909 A4G23_RS07295 c34a7e94f937178f36b0d31296c31776 185 Gene3D G3DSA:3.40.50.1950 5 148 3.1E-15 T 10-11-2016 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 A4G23_RS07295 c34a7e94f937178f36b0d31296c31776 185 Pfam PF02441 Flavoprotein 16 131 7.9E-6 T 10-11-2016 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 A4G23_RS07295 c34a7e94f937178f36b0d31296c31776 185 SUPERFAMILY SSF52507 2 157 1.15E-20 T 10-11-2016 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 A4G23_RS20560 57253b221ed00c139c4a067bfe92adbc 535 SUPERFAMILY SSF54211 6 169 1.02E-35 T 10-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold A4G23_RS20560 57253b221ed00c139c4a067bfe92adbc 535 Gene3D G3DSA:3.30.230.10 7 169 9.3E-38 T 10-11-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A4G23_RS20560 57253b221ed00c139c4a067bfe92adbc 535 SMART SM00382 231 415 3.3E-8 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS20560 57253b221ed00c139c4a067bfe92adbc 535 Pfam PF13541 Subunit ChlI of Mg-chelatase 21 141 1.4E-38 T 10-11-2016 A4G23_RS20560 57253b221ed00c139c4a067bfe92adbc 535 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 424 520 7.5E-21 T 10-11-2016 IPR025158 Mg chelatase-related protein, C-terminal domain A4G23_RS20560 57253b221ed00c139c4a067bfe92adbc 535 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 8 512 1.3E-134 T 10-11-2016 IPR004482 Mg chelatase-related protein A4G23_RS20560 57253b221ed00c139c4a067bfe92adbc 535 Gene3D G3DSA:3.40.50.300 211 411 6.7E-49 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS20560 57253b221ed00c139c4a067bfe92adbc 535 Pfam PF01078 Magnesium chelatase, subunit ChlI 211 417 7.9E-87 T 10-11-2016 IPR000523 Magnesium chelatase ChlI domain A4G23_RS20560 57253b221ed00c139c4a067bfe92adbc 535 SUPERFAMILY SSF52540 483 520 1.35E-42 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS20560 57253b221ed00c139c4a067bfe92adbc 535 SUPERFAMILY SSF52540 211 441 1.35E-42 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS01250 e74f022e9659940f0ff1b974e452b0bc 349 SUPERFAMILY SSF56059 1 342 6.83E-83 T 10-11-2016 A4G23_RS01250 e74f022e9659940f0ff1b974e452b0bc 349 Gene3D G3DSA:1.20.80.30 110 195 5.7E-22 T 10-11-2016 A4G23_RS01250 e74f022e9659940f0ff1b974e452b0bc 349 Gene3D G3DSA:3.30.1490.20 3 109 9.8E-38 T 10-11-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A4G23_RS01250 e74f022e9659940f0ff1b974e452b0bc 349 Gene3D G3DSA:3.30.1490.20 197 240 9.8E-38 T 10-11-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A4G23_RS01250 e74f022e9659940f0ff1b974e452b0bc 349 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 17 291 4.9E-15 T 10-11-2016 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 A4G23_RS01250 e74f022e9659940f0ff1b974e452b0bc 349 Gene3D G3DSA:3.30.470.20 242 341 5.8E-12 T 10-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 A4G23_RS09365 991702d431bf848c3734379d04ad4e4a 266 Pfam PF06182 ABC-2 family transporter protein 37 260 4.6E-17 T 10-11-2016 IPR010390 Protein of unknown function DUF990 A4G23_RS01515 598190a8938e2906321e226d513c1bae 215 SUPERFAMILY SSF53335 15 199 3.05E-36 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS01515 598190a8938e2906321e226d513c1bae 215 Gene3D G3DSA:3.40.50.150 13 189 4.7E-35 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS01515 598190a8938e2906321e226d513c1bae 215 Pfam PF13489 Methyltransferase domain 38 188 2.2E-17 T 10-11-2016 A4G23_RS10900 daf57c59d9b99597a92ba5d5e6d017cd 488 Gene3D G3DSA:3.30.70.1450 403 460 2.2E-7 T 10-11-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A4G23_RS10900 daf57c59d9b99597a92ba5d5e6d017cd 488 Pfam PF00999 Sodium/hydrogen exchanger family 6 376 1.5E-50 T 10-11-2016 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A4G23_RS10900 daf57c59d9b99597a92ba5d5e6d017cd 488 Pfam PF02080 TrkA-C domain 405 460 5.0E-10 T 10-11-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A4G23_RS10900 daf57c59d9b99597a92ba5d5e6d017cd 488 SUPERFAMILY SSF116726 400 468 8.11E-11 T 10-11-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A4G23_RS09005 2faadcfa59df9b6313a62540ed0c2036 182 Pfam PF13523 Acetyltransferase (GNAT) domain 15 158 2.2E-50 T 10-11-2016 A4G23_RS09005 2faadcfa59df9b6313a62540ed0c2036 182 SUPERFAMILY SSF55729 9 172 2.49E-41 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS09005 2faadcfa59df9b6313a62540ed0c2036 182 Gene3D G3DSA:3.40.630.30 9 178 3.3E-56 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS09005 2faadcfa59df9b6313a62540ed0c2036 182 SMART SM01006 12 59 9.3E-12 T 10-11-2016 IPR019432 Siderophore biosynthesis protein, conserved domain A4G23_RS24375 372722f450c2e7579c705a607021fe95 363 Hamap MF_00540 Adenosine deaminase [add]. 15 353 51.73 T 10-11-2016 IPR028893 Adenosine deaminase GO:0004000|GO:0009168 KEGG: 00230+3.5.4.4|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-74217 A4G23_RS24375 372722f450c2e7579c705a607021fe95 363 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 21 351 7.7E-77 T 10-11-2016 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 A4G23_RS24375 372722f450c2e7579c705a607021fe95 363 SUPERFAMILY SSF51556 15 345 7.49E-75 T 10-11-2016 IPR032466 Metal-dependent hydrolase A4G23_RS24375 372722f450c2e7579c705a607021fe95 363 Pfam PF00962 Adenosine/AMP deaminase 20 351 6.5E-83 T 10-11-2016 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 A4G23_RS24375 372722f450c2e7579c705a607021fe95 363 Gene3D G3DSA:3.20.20.140 16 352 8.2E-104 T 10-11-2016 A4G23_RS06755 f70f0f5cd216dc8393762cbf3716d178 322 PIRSF PIRSF005963 3 321 3.0E-120 T 10-11-2016 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 A4G23_RS06755 f70f0f5cd216dc8393762cbf3716d178 322 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 24 61 7.1E-7 T 10-11-2016 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 A4G23_RS06755 f70f0f5cd216dc8393762cbf3716d178 322 SUPERFAMILY SSF102114 36 312 1.16E-62 T 10-11-2016 A4G23_RS06755 f70f0f5cd216dc8393762cbf3716d178 322 Hamap MF_00206 Lipoyl synthase [lipA]. 1 313 136.869 T 10-11-2016 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 A4G23_RS06755 f70f0f5cd216dc8393762cbf3716d178 322 TIGRFAM TIGR00510 lipA: lipoyl synthase 18 310 5.6E-95 T 10-11-2016 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 A4G23_RS06755 f70f0f5cd216dc8393762cbf3716d178 322 Pfam PF04055 Radical SAM superfamily 82 241 1.9E-12 T 10-11-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 A4G23_RS06755 f70f0f5cd216dc8393762cbf3716d178 322 Gene3D G3DSA:3.20.20.70 39 310 3.0E-66 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS06755 f70f0f5cd216dc8393762cbf3716d178 322 SMART SM00729 72 286 4.0E-15 T 10-11-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 A4G23_RS24795 7c51fad1b68585cd8df29485b4070e6e 195 Gene3D G3DSA:1.10.10.60 10 68 4.9E-20 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS24795 7c51fad1b68585cd8df29485b4070e6e 195 SUPERFAMILY SSF46689 12 72 2.05E-16 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS24795 7c51fad1b68585cd8df29485b4070e6e 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 69 1.6E-12 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS24795 7c51fad1b68585cd8df29485b4070e6e 195 SUPERFAMILY SSF48498 86 192 1.29E-24 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS24795 7c51fad1b68585cd8df29485b4070e6e 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 2.7E-6 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS24795 7c51fad1b68585cd8df29485b4070e6e 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 2.7E-6 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS24795 7c51fad1b68585cd8df29485b4070e6e 195 Gene3D G3DSA:1.10.357.10 71 193 4.3E-34 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS06175 14fcfdf35873ee48f776dcc98bd9bda8 530 TIGRFAM TIGR00831 a_cpa1: Na+/H+ antiporter 10 527 2.4E-93 T 10-11-2016 IPR004705 Cation/H+ exchanger, CPA1 family, bacteria GO:0006812|GO:0015299|GO:0016021 A4G23_RS06175 14fcfdf35873ee48f776dcc98bd9bda8 530 Pfam PF00999 Sodium/hydrogen exchanger family 9 406 4.2E-53 T 10-11-2016 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A4G23_RS06975 92aab677164a20a06bdc6e15a20f412e 424 Gene3D G3DSA:1.20.1250.20 19 203 8.8E-18 T 10-11-2016 A4G23_RS06975 92aab677164a20a06bdc6e15a20f412e 424 Gene3D G3DSA:1.20.1250.20 240 402 8.0E-15 T 10-11-2016 A4G23_RS06975 92aab677164a20a06bdc6e15a20f412e 424 SUPERFAMILY SSF103473 19 403 8.11E-40 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS06975 92aab677164a20a06bdc6e15a20f412e 424 Pfam PF05977 Transmembrane secretion effector 13 404 3.4E-26 T 10-11-2016 IPR010290 Transmembrane secretion effector A4G23_RS03610 2350e9a89b7728dfbb749f290c359895 201 Gene3D G3DSA:3.40.50.300 4 168 9.9E-47 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS03610 2350e9a89b7728dfbb749f290c359895 201 Pfam PF01202 Shikimate kinase 13 167 8.9E-41 T 10-11-2016 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 A4G23_RS03610 2350e9a89b7728dfbb749f290c359895 201 PRINTS PR01100 Shikimate kinase family signature 7 22 9.3E-17 T 10-11-2016 A4G23_RS03610 2350e9a89b7728dfbb749f290c359895 201 PRINTS PR01100 Shikimate kinase family signature 97 114 9.3E-17 T 10-11-2016 A4G23_RS03610 2350e9a89b7728dfbb749f290c359895 201 PRINTS PR01100 Shikimate kinase family signature 31 44 9.3E-17 T 10-11-2016 A4G23_RS03610 2350e9a89b7728dfbb749f290c359895 201 PRINTS PR01100 Shikimate kinase family signature 59 67 9.3E-17 T 10-11-2016 A4G23_RS03610 2350e9a89b7728dfbb749f290c359895 201 PRINTS PR01100 Shikimate kinase family signature 77 86 9.3E-17 T 10-11-2016 A4G23_RS03610 2350e9a89b7728dfbb749f290c359895 201 ProSitePatterns PS01128 Shikimate kinase signature. 60 85 - T 10-11-2016 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 A4G23_RS03610 2350e9a89b7728dfbb749f290c359895 201 SUPERFAMILY SSF52540 5 167 1.58E-25 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS03610 2350e9a89b7728dfbb749f290c359895 201 Hamap MF_00109 Shikimate kinase [aroK]. 4 168 25.649 T 10-11-2016 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 A4G23_RS02440 4e16b63e86a9c47503697d6dd2173cc5 174 Pfam PF10400 Virulence activator alpha C-term 91 168 2.0E-10 T 10-11-2016 IPR018309 Transcription regulator PadR, C-terminal A4G23_RS02440 4e16b63e86a9c47503697d6dd2173cc5 174 Gene3D G3DSA:1.10.10.10 2 85 3.3E-28 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS02440 4e16b63e86a9c47503697d6dd2173cc5 174 Pfam PF03551 Transcriptional regulator PadR-like family 5 79 1.7E-20 T 10-11-2016 IPR005149 Transcription regulator PadR, N-terminal A4G23_RS02440 4e16b63e86a9c47503697d6dd2173cc5 174 SUPERFAMILY SSF46785 2 169 4.38E-38 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS20570 9db6a2423d85438484845d509907cdf9 279 Pfam PF04545 Sigma-70, region 4 223 272 2.0E-18 T 10-11-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS20570 9db6a2423d85438484845d509907cdf9 279 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 45 274 8.5E-35 T 10-11-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS20570 9db6a2423d85438484845d509907cdf9 279 Gene3D G3DSA:1.10.601.10 30 112 8.8E-17 T 10-11-2016 A4G23_RS20570 9db6a2423d85438484845d509907cdf9 279 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 76 89 - T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS20570 9db6a2423d85438484845d509907cdf9 279 PIRSF PIRSF000770 26 278 4.8E-73 T 10-11-2016 IPR016263 RNA polymerase sporulation-specific sigma factor GO:0003677|GO:0006351|GO:0016987|GO:0030435 A4G23_RS20570 9db6a2423d85438484845d509907cdf9 279 Gene3D G3DSA:1.10.10.10 212 276 2.0E-16 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS20570 9db6a2423d85438484845d509907cdf9 279 SUPERFAMILY SSF88659 122 201 2.79E-14 T 10-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS20570 9db6a2423d85438484845d509907cdf9 279 Pfam PF04539 Sigma-70 region 3 129 209 1.1E-7 T 10-11-2016 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS20570 9db6a2423d85438484845d509907cdf9 279 Gene3D G3DSA:1.10.10.10 121 166 4.3E-9 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS20570 9db6a2423d85438484845d509907cdf9 279 TIGRFAM TIGR02479 FliA_WhiG: RNA polymerase sigma factor, FliA/WhiG family 49 274 2.3E-86 T 10-11-2016 IPR012845 RNA polymerase sigma factor, FliA/WhiG GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 A4G23_RS20570 9db6a2423d85438484845d509907cdf9 279 SUPERFAMILY SSF88659 188 276 6.35E-24 T 10-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS20570 9db6a2423d85438484845d509907cdf9 279 SUPERFAMILY SSF88946 19 121 1.54E-26 T 10-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS20570 9db6a2423d85438484845d509907cdf9 279 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 244 270 - T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS20570 9db6a2423d85438484845d509907cdf9 279 PRINTS PR00046 Major sigma-70 factor signature 76 89 7.6E-12 T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS20570 9db6a2423d85438484845d509907cdf9 279 PRINTS PR00046 Major sigma-70 factor signature 227 239 7.6E-12 T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS20570 9db6a2423d85438484845d509907cdf9 279 PRINTS PR00046 Major sigma-70 factor signature 244 259 7.6E-12 T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS20570 9db6a2423d85438484845d509907cdf9 279 PRINTS PR00046 Major sigma-70 factor signature 259 270 7.6E-12 T 10-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS20570 9db6a2423d85438484845d509907cdf9 279 Pfam PF04542 Sigma-70 region 2 49 121 3.7E-16 T 10-11-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS14435 01c36f64293f94ad156ff4aee85f0702 194 Pfam PF14016 Protein of unknown function (DUF4232) 53 188 4.7E-27 T 10-11-2016 IPR025326 Protein of unknown function DUF4232 A4G23_RS16705 0b9c94dc9d55f4252a281349f333a54e 439 PIRSF PIRSF004557 1 439 2.3E-125 T 10-11-2016 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A4G23_RS16705 0b9c94dc9d55f4252a281349f333a54e 439 SUPERFAMILY SSF103491 2 429 1.96E-127 T 10-11-2016 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A4G23_RS16705 0b9c94dc9d55f4252a281349f333a54e 439 ProSitePatterns PS00756 Protein secY signature 2. 177 194 - T 10-11-2016 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A4G23_RS16705 0b9c94dc9d55f4252a281349f333a54e 439 Pfam PF00344 SecY translocase 74 422 1.2E-117 T 10-11-2016 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A4G23_RS16705 0b9c94dc9d55f4252a281349f333a54e 439 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 438 29.914 T 10-11-2016 IPR026593 Protein translocase subunit SecY A4G23_RS16705 0b9c94dc9d55f4252a281349f333a54e 439 Gene3D G3DSA:1.10.3370.10 2 439 1.6E-158 T 10-11-2016 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A4G23_RS16705 0b9c94dc9d55f4252a281349f333a54e 439 ProSitePatterns PS00755 Protein secY signature 1. 74 93 - T 10-11-2016 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A4G23_RS16705 0b9c94dc9d55f4252a281349f333a54e 439 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 434 3.7E-148 T 10-11-2016 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A4G23_RS16705 0b9c94dc9d55f4252a281349f333a54e 439 PRINTS PR00303 Preprotein translocase SecY subunit signature 317 339 5.6E-106 T 10-11-2016 A4G23_RS16705 0b9c94dc9d55f4252a281349f333a54e 439 PRINTS PR00303 Preprotein translocase SecY subunit signature 114 137 5.6E-106 T 10-11-2016 A4G23_RS16705 0b9c94dc9d55f4252a281349f333a54e 439 PRINTS PR00303 Preprotein translocase SecY subunit signature 73 93 5.6E-106 T 10-11-2016 A4G23_RS16705 0b9c94dc9d55f4252a281349f333a54e 439 PRINTS PR00303 Preprotein translocase SecY subunit signature 184 207 5.6E-106 T 10-11-2016 A4G23_RS16705 0b9c94dc9d55f4252a281349f333a54e 439 PRINTS PR00303 Preprotein translocase SecY subunit signature 275 294 5.6E-106 T 10-11-2016 A4G23_RS16705 0b9c94dc9d55f4252a281349f333a54e 439 PRINTS PR00303 Preprotein translocase SecY subunit signature 372 390 5.6E-106 T 10-11-2016 A4G23_RS16705 0b9c94dc9d55f4252a281349f333a54e 439 PRINTS PR00303 Preprotein translocase SecY subunit signature 158 183 5.6E-106 T 10-11-2016 A4G23_RS16705 0b9c94dc9d55f4252a281349f333a54e 439 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 5.6E-106 T 10-11-2016 A4G23_RS16705 0b9c94dc9d55f4252a281349f333a54e 439 PRINTS PR00303 Preprotein translocase SecY subunit signature 407 425 5.6E-106 T 10-11-2016 A4G23_RS20085 1bfb8f28135d38728b86001476140c45 504 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 165 179 - T 10-11-2016 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 A4G23_RS20085 1bfb8f28135d38728b86001476140c45 504 Gene3D G3DSA:1.10.10.410 443 499 1.7E-4 T 10-11-2016 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal A4G23_RS20085 1bfb8f28135d38728b86001476140c45 504 SUPERFAMILY SSF89095 352 499 8.72E-26 T 10-11-2016 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 A4G23_RS20085 1bfb8f28135d38728b86001476140c45 504 Pfam PF02934 GatB/GatE catalytic domain 20 314 8.6E-105 T 10-11-2016 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 A4G23_RS20085 1bfb8f28135d38728b86001476140c45 504 Pfam PF02637 GatB domain 352 499 7.2E-40 T 10-11-2016 IPR018027 Asn/Gln amidotransferase GO:0016884 A4G23_RS20085 1bfb8f28135d38728b86001476140c45 504 SMART SM00845 352 499 1.0E-57 T 10-11-2016 IPR018027 Asn/Gln amidotransferase GO:0016884 A4G23_RS20085 1bfb8f28135d38728b86001476140c45 504 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 16 500 36.27 T 10-11-2016 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 A4G23_RS20085 1bfb8f28135d38728b86001476140c45 504 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 16 499 1.3E-143 T 10-11-2016 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 A4G23_RS20085 1bfb8f28135d38728b86001476140c45 504 SUPERFAMILY SSF55931 19 321 8.5E-113 T 10-11-2016 A4G23_RS16010 5c73b53d100699a5ac95762668dfd8e1 233 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 4 229 34.649 T 10-11-2016 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 A4G23_RS16010 5c73b53d100699a5ac95762668dfd8e1 233 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 24 39 - T 10-11-2016 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 A4G23_RS16010 5c73b53d100699a5ac95762668dfd8e1 233 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 13 229 3.2E-71 T 10-11-2016 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 A4G23_RS16010 5c73b53d100699a5ac95762668dfd8e1 233 SUPERFAMILY SSF53335 5 228 1.19E-47 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS16010 5c73b53d100699a5ac95762668dfd8e1 233 Gene3D G3DSA:3.40.50.150 12 226 1.8E-47 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS16010 5c73b53d100699a5ac95762668dfd8e1 233 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 137 151 - T 10-11-2016 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 A4G23_RS16010 5c73b53d100699a5ac95762668dfd8e1 233 Pfam PF01209 ubiE/COQ5 methyltransferase family 11 229 7.1E-62 T 10-11-2016 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 A4G23_RS05170 87e33e9ded1fa6a870061c926737e613 163 Pfam PF11298 Protein of unknown function (DUF3099) 12 79 2.1E-22 T 10-11-2016 IPR021449 Protein of unknown function DUF3099 A4G23_RS19500 ee1c63255f389be8c07eb7d8f5a8dd06 370 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 109 265 3.1E-58 T 10-11-2016 IPR004474 Cell envelope-related transcriptional attenuator domain A4G23_RS19500 ee1c63255f389be8c07eb7d8f5a8dd06 370 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 110 265 9.7E-49 T 10-11-2016 IPR004474 Cell envelope-related transcriptional attenuator domain A4G23_RS05665 fbb915877eabf90ed026f3af55fe82a2 76 Pfam PF03840 Preprotein translocase SecG subunit 3 70 1.1E-18 T 10-11-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 A4G23_RS05665 fbb915877eabf90ed026f3af55fe82a2 76 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 3 71 1.4E-19 T 10-11-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 A4G23_RS14770 9d3b263f0ff1f10bfa59d7514699a2f8 280 Pfam PF13349 Putative adhesin 60 276 2.1E-8 T 10-11-2016 IPR025164 Putative adhesin A4G23_RS23900 eaa44461e9a9af2eb88635f1a196181b 234 Pfam PF00005 ABC transporter 22 182 3.0E-31 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS23900 eaa44461e9a9af2eb88635f1a196181b 234 SUPERFAMILY SSF52540 5 232 6.71E-61 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS23900 eaa44461e9a9af2eb88635f1a196181b 234 Gene3D G3DSA:3.40.50.300 4 232 1.4E-62 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS23900 eaa44461e9a9af2eb88635f1a196181b 234 SMART SM00382 31 232 2.6E-13 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS23900 eaa44461e9a9af2eb88635f1a196181b 234 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS25155 4e6964174671578ca451ee7adb2682f2 398 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 227 376 3.1E-31 T 10-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4G23_RS25155 4e6964174671578ca451ee7adb2682f2 398 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 10 118 5.1E-26 T 10-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 A4G23_RS25155 4e6964174671578ca451ee7adb2682f2 398 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 215 1.2E-20 T 10-11-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 A4G23_RS25155 4e6964174671578ca451ee7adb2682f2 398 Gene3D G3DSA:1.10.540.10 10 118 7.0E-31 T 10-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 A4G23_RS25155 4e6964174671578ca451ee7adb2682f2 398 Gene3D G3DSA:1.20.140.10 217 382 1.5E-40 T 10-11-2016 A4G23_RS25155 4e6964174671578ca451ee7adb2682f2 398 Gene3D G3DSA:2.40.110.10 123 216 5.0E-32 T 10-11-2016 A4G23_RS25155 4e6964174671578ca451ee7adb2682f2 398 SUPERFAMILY SSF56645 9 234 1.06E-66 T 10-11-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 A4G23_RS25155 4e6964174671578ca451ee7adb2682f2 398 SUPERFAMILY SSF47203 225 382 1.93E-32 T 10-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4G23_RS10590 2e47bb23c825e174eb2f0ad5198fef89 275 Gene3D G3DSA:3.40.50.150 9 188 1.6E-31 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS10590 2e47bb23c825e174eb2f0ad5198fef89 275 Pfam PF13649 Methyltransferase domain 44 124 3.8E-15 T 10-11-2016 A4G23_RS10590 2e47bb23c825e174eb2f0ad5198fef89 275 Gene3D G3DSA:1.10.150.290 198 255 1.3E-24 T 10-11-2016 IPR023149 Trans-aconitate 2-methyltransferase, C-terminal GO:0030798 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 A4G23_RS10590 2e47bb23c825e174eb2f0ad5198fef89 275 SUPERFAMILY SSF53335 4 215 1.51E-30 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS10590 2e47bb23c825e174eb2f0ad5198fef89 275 Hamap MF_00560 Trans-aconitate 2-methyltransferase [tam]. 5 274 42.025 T 10-11-2016 IPR023506 Trans-aconitate 2-methyltransferase GO:0030798 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 A4G23_RS02280 f966c6ca7fd4e52a7b3979e788a66449 196 Pfam PF13580 SIS domain 7 138 1.0E-19 T 10-11-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 A4G23_RS02280 f966c6ca7fd4e52a7b3979e788a66449 196 Gene3D G3DSA:3.40.50.10490 6 176 2.5E-43 T 10-11-2016 A4G23_RS02280 f966c6ca7fd4e52a7b3979e788a66449 196 SUPERFAMILY SSF53697 14 177 1.98E-35 T 10-11-2016 A4G23_RS13270 3fc37e603bff4621d8039497b4c6d310 409 ProDom PD031536 MEMBRANE TRANSMEMBRANE YVAX YITN 302 384 0.002 T 10-11-2016 A4G23_RS13270 3fc37e603bff4621d8039497b4c6d310 409 SMART SM00752 56 395 1.3E-88 T 10-11-2016 IPR011020 HTTM Reactome: R-HSA-159740 A4G23_RS06935 558f2cbc7160282cb1fa5e1d73451ce9 567 Pfam PF00394 Multicopper oxidase 316 416 2.3E-21 T 10-11-2016 IPR001117 Multicopper oxidase, type 1 GO:0016491|GO:0055114 A4G23_RS06935 558f2cbc7160282cb1fa5e1d73451ce9 567 Gene3D G3DSA:2.60.40.420 72 200 9.2E-33 T 10-11-2016 IPR008972 Cupredoxin A4G23_RS06935 558f2cbc7160282cb1fa5e1d73451ce9 567 SUPERFAMILY SSF49503 74 221 6.79E-36 T 10-11-2016 IPR008972 Cupredoxin A4G23_RS06935 558f2cbc7160282cb1fa5e1d73451ce9 567 ProSitePatterns PS00079 Multicopper oxidases signature 1. 543 563 - T 10-11-2016 IPR033138 Multicopper oxidases, conserved site A4G23_RS06935 558f2cbc7160282cb1fa5e1d73451ce9 567 SUPERFAMILY SSF49503 200 245 2.19E-31 T 10-11-2016 IPR008972 Cupredoxin A4G23_RS06935 558f2cbc7160282cb1fa5e1d73451ce9 567 SUPERFAMILY SSF49503 295 429 2.19E-31 T 10-11-2016 IPR008972 Cupredoxin A4G23_RS06935 558f2cbc7160282cb1fa5e1d73451ce9 567 SUPERFAMILY SSF49503 446 562 1.66E-35 T 10-11-2016 IPR008972 Cupredoxin A4G23_RS06935 558f2cbc7160282cb1fa5e1d73451ce9 567 ProSitePatterns PS00080 Multicopper oxidases signature 2. 548 559 - T 10-11-2016 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 A4G23_RS06935 558f2cbc7160282cb1fa5e1d73451ce9 567 Pfam PF07732 Multicopper oxidase 96 198 1.0E-33 T 10-11-2016 IPR011707 Multicopper oxidase, type 3 GO:0005507 A4G23_RS06935 558f2cbc7160282cb1fa5e1d73451ce9 567 Pfam PF07731 Multicopper oxidase 455 563 9.8E-26 T 10-11-2016 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 A4G23_RS06935 558f2cbc7160282cb1fa5e1d73451ce9 567 Gene3D G3DSA:2.60.40.420 203 243 7.5E-48 T 10-11-2016 IPR008972 Cupredoxin A4G23_RS06935 558f2cbc7160282cb1fa5e1d73451ce9 567 Gene3D G3DSA:2.60.40.420 293 447 7.5E-48 T 10-11-2016 IPR008972 Cupredoxin A4G23_RS06935 558f2cbc7160282cb1fa5e1d73451ce9 567 Gene3D G3DSA:2.60.40.420 448 565 1.1E-41 T 10-11-2016 IPR008972 Cupredoxin A4G23_RS08140 d497304f4bd857ab2bbbb1b6ddae4389 323 Gene3D G3DSA:3.90.1530.10 239 286 4.8E-5 T 10-11-2016 A4G23_RS08140 d497304f4bd857ab2bbbb1b6ddae4389 323 Pfam PF07591 Pretoxin HINT domain 82 210 1.2E-20 T 10-11-2016 A4G23_RS08140 d497304f4bd857ab2bbbb1b6ddae4389 323 SMART SM00306 66 168 2.1E-8 T 10-11-2016 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 A4G23_RS08140 d497304f4bd857ab2bbbb1b6ddae4389 323 SUPERFAMILY SSF110849 249 286 5.23E-6 T 10-11-2016 IPR003115 ParB/Sulfiredoxin A4G23_RS08140 d497304f4bd857ab2bbbb1b6ddae4389 323 SUPERFAMILY SSF51294 68 211 4.97E-20 T 10-11-2016 IPR028992 Hedgehog/Intein (Hint) domain A4G23_RS08140 d497304f4bd857ab2bbbb1b6ddae4389 323 Gene3D G3DSA:2.170.16.10 65 238 9.3E-27 T 10-11-2016 IPR028992 Hedgehog/Intein (Hint) domain A4G23_RS07410 bd533680e030583c0eb3b36f7a45ae57 152 Gene3D G3DSA:3.40.30.10 2 152 1.9E-50 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS07410 bd533680e030583c0eb3b36f7a45ae57 152 Pfam PF00578 AhpC/TSA family 5 130 7.7E-40 T 10-11-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A4G23_RS07410 bd533680e030583c0eb3b36f7a45ae57 152 PIRSF PIRSF000239 1 152 1.3E-30 T 10-11-2016 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A4G23_RS07410 bd533680e030583c0eb3b36f7a45ae57 152 SUPERFAMILY SSF52833 1 152 1.33E-49 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS15015 097bd32c26b86db1a940b8c612c29cae 447 SUPERFAMILY SSF53383 86 437 3.94E-62 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS15015 097bd32c26b86db1a940b8c612c29cae 447 Pfam PF00155 Aminotransferase class I and II 128 433 2.5E-13 T 10-11-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4G23_RS15015 097bd32c26b86db1a940b8c612c29cae 447 Pfam PF00392 Bacterial regulatory proteins, gntR family 5 67 6.0E-10 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS15015 097bd32c26b86db1a940b8c612c29cae 447 Gene3D G3DSA:3.40.640.10 125 331 2.8E-42 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS15015 097bd32c26b86db1a940b8c612c29cae 447 SUPERFAMILY SSF46785 4 71 2.07E-12 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS15015 097bd32c26b86db1a940b8c612c29cae 447 SMART SM00345 8 67 1.3E-6 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS15015 097bd32c26b86db1a940b8c612c29cae 447 Gene3D G3DSA:1.10.10.10 4 68 1.4E-16 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS02460 74d4b7806d4c173a199b1a7c51142b58 450 Gene3D G3DSA:1.20.58.370 23 54 2.6E-4 T 10-11-2016 A4G23_RS02460 74d4b7806d4c173a199b1a7c51142b58 450 SUPERFAMILY SSF49478 247 300 3.26E-8 T 10-11-2016 A4G23_RS02460 74d4b7806d4c173a199b1a7c51142b58 450 Gene3D G3DSA:2.60.40.10 245 299 1.3E-11 T 10-11-2016 IPR013783 Immunoglobulin-like fold A4G23_RS02460 74d4b7806d4c173a199b1a7c51142b58 450 SUPERFAMILY SSF161098 303 436 1.24E-41 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS02460 74d4b7806d4c173a199b1a7c51142b58 450 SUPERFAMILY SSF161098 67 155 1.24E-41 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS02460 74d4b7806d4c173a199b1a7c51142b58 450 Pfam PF13620 Carboxypeptidase regulatory-like domain 247 301 2.9E-8 T 10-11-2016 A4G23_RS02460 74d4b7806d4c173a199b1a7c51142b58 450 Gene3D G3DSA:1.10.3720.10 71 155 2.2E-59 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS02460 74d4b7806d4c173a199b1a7c51142b58 450 Gene3D G3DSA:1.10.3720.10 303 448 2.2E-59 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS02460 74d4b7806d4c173a199b1a7c51142b58 450 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 305 440 1.7E-17 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS02460 74d4b7806d4c173a199b1a7c51142b58 450 SUPERFAMILY SSF160964 23 63 3.27E-5 T 10-11-2016 A4G23_RS03855 8f133af4b43835e02145f340488fd8cc 270 Gene3D G3DSA:3.30.470.10 2 111 4.1E-31 T 10-11-2016 A4G23_RS03855 8f133af4b43835e02145f340488fd8cc 270 SUPERFAMILY SSF56752 3 265 2.09E-72 T 10-11-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 A4G23_RS03855 8f133af4b43835e02145f340488fd8cc 270 Gene3D G3DSA:3.20.10.10 124 258 1.6E-43 T 10-11-2016 A4G23_RS03855 8f133af4b43835e02145f340488fd8cc 270 Pfam PF01063 Amino-transferase class IV 29 242 2.0E-50 T 10-11-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 A4G23_RS03855 8f133af4b43835e02145f340488fd8cc 270 ProSitePatterns PS00770 Aminotransferases class-IV signature. 174 203 - T 10-11-2016 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 A4G23_RS01910 587d043ed579ca3fa3af73fe1d045b93 137 SUPERFAMILY SSF81324 47 132 4.06E-19 T 10-11-2016 A4G23_RS01910 587d043ed579ca3fa3af73fe1d045b93 137 Gene3D G3DSA:1.10.287.70 48 133 6.5E-16 T 10-11-2016 A4G23_RS01910 587d043ed579ca3fa3af73fe1d045b93 137 Pfam PF07885 Ion channel 52 131 3.0E-17 T 10-11-2016 IPR013099 Potassium channel domain A4G23_RS01055 282d2860eda9c2a873be223f1919f863 328 Gene3D G3DSA:3.90.25.10 180 317 3.8E-49 T 10-11-2016 A4G23_RS01055 282d2860eda9c2a873be223f1919f863 328 Gene3D G3DSA:3.40.50.720 10 179 4.7E-48 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS01055 282d2860eda9c2a873be223f1919f863 328 Pfam PF01370 NAD dependent epimerase/dehydratase family 12 246 5.7E-49 T 10-11-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 A4G23_RS01055 282d2860eda9c2a873be223f1919f863 328 SUPERFAMILY SSF51735 10 315 3.9E-85 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS24395 bf25e07a4c27ac0538d223cc9b96e991 267 Pfam PF08241 Methyltransferase domain 41 138 4.5E-26 T 10-11-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 A4G23_RS24395 bf25e07a4c27ac0538d223cc9b96e991 267 SUPERFAMILY SSF53335 6 247 1.7E-43 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS24395 bf25e07a4c27ac0538d223cc9b96e991 267 Gene3D G3DSA:3.40.50.150 5 252 5.4E-46 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS14055 0009f5609c59985a288c46b872820535 473 Gene3D G3DSA:3.40.710.10 75 327 4.6E-66 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS14055 0009f5609c59985a288c46b872820535 473 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 77 306 3.4E-33 T 10-11-2016 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 A4G23_RS14055 0009f5609c59985a288c46b872820535 473 SUPERFAMILY SSF56601 72 326 6.22E-49 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS14055 0009f5609c59985a288c46b872820535 473 SUPERFAMILY SSF56601 23 35 6.22E-49 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS03330 bc0a084b88980d95506d96098ae14b6d 478 Pfam PF13529 Peptidase_C39 like family 266 416 9.1E-27 T 10-11-2016 A4G23_RS23830 92cfc4e12a4bd94b80467e36d9b9580f 547 Gene3D G3DSA:3.40.50.980 211 356 2.6E-53 T 10-11-2016 A4G23_RS23830 92cfc4e12a4bd94b80467e36d9b9580f 547 ProSitePatterns PS00455 Putative AMP-binding domain signature. 196 207 - T 10-11-2016 IPR020845 AMP-binding, conserved site A4G23_RS23830 92cfc4e12a4bd94b80467e36d9b9580f 547 Pfam PF00501 AMP-binding enzyme 34 447 1.7E-115 T 10-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A4G23_RS23830 92cfc4e12a4bd94b80467e36d9b9580f 547 Gene3D G3DSA:3.40.50.980 28 210 4.8E-40 T 10-11-2016 A4G23_RS23830 92cfc4e12a4bd94b80467e36d9b9580f 547 SUPERFAMILY SSF56801 27 542 5.23E-166 T 10-11-2016 A4G23_RS23830 92cfc4e12a4bd94b80467e36d9b9580f 547 Gene3D G3DSA:3.30.300.30 442 542 1.6E-34 T 10-11-2016 A4G23_RS23830 92cfc4e12a4bd94b80467e36d9b9580f 547 Gene3D G3DSA:2.30.38.10 364 438 2.9E-29 T 10-11-2016 A4G23_RS23830 92cfc4e12a4bd94b80467e36d9b9580f 547 Pfam PF13193 AMP-binding enzyme C-terminal domain 456 532 9.1E-22 T 10-11-2016 IPR025110 AMP-binding enzyme C-terminal domain A4G23_RS15120 4c64b6d0e362d1cee20d54f2e2e4cbeb 77 Pfam PF03777 Small secreted domain (DUF320) 21 76 3.2E-29 T 10-11-2016 IPR005528 Domain of unknown function DUF320, Streptomyces species A4G23_RS18575 d10372912f56e49ce56758d9ed963b0b 151 Hamap MF_00237 Sec-independent protein translocase protein TatB [tatB]. 2 138 13.954 T 10-11-2016 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 A4G23_RS18575 d10372912f56e49ce56758d9ed963b0b 151 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 22 41 4.5E-9 T 10-11-2016 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 A4G23_RS18575 d10372912f56e49ce56758d9ed963b0b 151 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 41 59 4.5E-9 T 10-11-2016 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 A4G23_RS18575 d10372912f56e49ce56758d9ed963b0b 151 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 2 22 4.5E-9 T 10-11-2016 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 A4G23_RS03115 b39d5e63190aeb44e22b32efeb2da8c7 149 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 3 124 5.0E-38 T 10-11-2016 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 A4G23_RS03115 b39d5e63190aeb44e22b32efeb2da8c7 149 Gene3D G3DSA:2.70.70.10 3 148 8.2E-44 T 10-11-2016 A4G23_RS03115 b39d5e63190aeb44e22b32efeb2da8c7 149 SUPERFAMILY SSF51261 3 147 2.96E-36 T 10-11-2016 IPR011055 Duplicated hybrid motif A4G23_RS22955 9a7b5c40831a7dbd928fc5835e046d7e 222 PIRSF PIRSF000440 1 216 4.3E-76 T 10-11-2016 IPR001707 Chloramphenicol acetyltransferase GO:0008811 A4G23_RS22955 9a7b5c40831a7dbd928fc5835e046d7e 222 Pfam PF00302 Chloramphenicol acetyltransferase 5 207 2.2E-87 T 10-11-2016 IPR001707 Chloramphenicol acetyltransferase GO:0008811 A4G23_RS22955 9a7b5c40831a7dbd928fc5835e046d7e 222 SUPERFAMILY SSF52777 5 214 2.16E-65 T 10-11-2016 A4G23_RS22955 9a7b5c40831a7dbd928fc5835e046d7e 222 ProDom PD002660 TRANSFERASE CHLORAMPHENICOL ACYLTRANSFERASE ACETYLTRANSFERASE ANTIBIOTIC RESISTANCE PLASMID CAT O-ACETYLTRANSFERASE DIRECT 14 206 1.0E-93 T 10-11-2016 IPR001707 Chloramphenicol acetyltransferase GO:0008811 A4G23_RS22955 9a7b5c40831a7dbd928fc5835e046d7e 222 Gene3D G3DSA:3.30.559.10 5 210 1.7E-70 T 10-11-2016 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 A4G23_RS22955 9a7b5c40831a7dbd928fc5835e046d7e 222 ProSitePatterns PS00100 Chloramphenicol acetyltransferase active site. 188 198 - T 10-11-2016 IPR018372 Chloramphenicol acetyltransferase, active site GO:0008811 A4G23_RS22955 9a7b5c40831a7dbd928fc5835e046d7e 222 SMART SM01059 4 207 1.3E-74 T 10-11-2016 IPR001707 Chloramphenicol acetyltransferase GO:0008811 A4G23_RS26710 2c8b26dba439e0b174d9668a8bf8130e 163 SUPERFAMILY SSF159888 64 133 4.84E-11 T 10-11-2016 A4G23_RS08385 6726d6b368950944883a0c72c0959e6e 211 Gene3D G3DSA:3.40.30.10 5 169 6.8E-12 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS08385 6726d6b368950944883a0c72c0959e6e 211 SUPERFAMILY SSF52833 7 171 3.22E-22 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS08385 6726d6b368950944883a0c72c0959e6e 211 Pfam PF01323 DSBA-like thioredoxin domain 9 157 4.3E-7 T 10-11-2016 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 A4G23_RS12655 ddb6f2f7e3bf3db2af34ec3f2c164a4b 304 Gene3D G3DSA:3.40.50.300 1 224 3.4E-57 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS12655 ddb6f2f7e3bf3db2af34ec3f2c164a4b 304 SMART SM00382 26 204 1.2E-7 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS12655 ddb6f2f7e3bf3db2af34ec3f2c164a4b 304 Pfam PF00005 ABC transporter 18 156 1.5E-23 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS12655 ddb6f2f7e3bf3db2af34ec3f2c164a4b 304 SUPERFAMILY SSF52540 2 224 8.91E-55 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS26770 aecbf08404de0b5a08f414be48b55b51 292 Pfam PF03756 A-factor biosynthesis hotdog domain 182 236 2.0E-7 T 10-11-2016 IPR005509 A-factor biosynthesis hotdog domain A4G23_RS26770 aecbf08404de0b5a08f414be48b55b51 292 Pfam PF03756 A-factor biosynthesis hotdog domain 57 145 1.2E-8 T 10-11-2016 IPR005509 A-factor biosynthesis hotdog domain A4G23_RS09720 e3d147bd5ddb0d6ebf5ad9c92915e8bf 408 Gene3D G3DSA:3.90.226.10 216 395 1.8E-42 T 10-11-2016 IPR029045 ClpP/crotonase-like domain A4G23_RS09720 e3d147bd5ddb0d6ebf5ad9c92915e8bf 408 SUPERFAMILY SSF50156 109 222 9.86E-17 T 10-11-2016 IPR001478 PDZ domain GO:0005515 A4G23_RS09720 e3d147bd5ddb0d6ebf5ad9c92915e8bf 408 SUPERFAMILY SSF52096 225 394 4.31E-43 T 10-11-2016 IPR029045 ClpP/crotonase-like domain A4G23_RS09720 e3d147bd5ddb0d6ebf5ad9c92915e8bf 408 SUPERFAMILY SSF52096 79 144 4.31E-43 T 10-11-2016 IPR029045 ClpP/crotonase-like domain A4G23_RS09720 e3d147bd5ddb0d6ebf5ad9c92915e8bf 408 SMART SM00228 118 207 8.5E-9 T 10-11-2016 IPR001478 PDZ domain GO:0005515 A4G23_RS09720 e3d147bd5ddb0d6ebf5ad9c92915e8bf 408 Pfam PF13180 PDZ domain 134 213 1.8E-8 T 10-11-2016 IPR001478 PDZ domain GO:0005515 A4G23_RS09720 e3d147bd5ddb0d6ebf5ad9c92915e8bf 408 Pfam PF03572 Peptidase family S41 234 387 8.3E-37 T 10-11-2016 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 A4G23_RS09720 e3d147bd5ddb0d6ebf5ad9c92915e8bf 408 SMART SM00245 207 390 5.5E-35 T 10-11-2016 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 A4G23_RS09720 e3d147bd5ddb0d6ebf5ad9c92915e8bf 408 Gene3D G3DSA:2.30.42.10 125 215 2.5E-20 T 10-11-2016 IPR001478 PDZ domain GO:0005515 A4G23_RS01240 5c2fc7f240c531143d27af3b79347090 100 ProDom PD280340 RV1738/MT1780 MB2665C MB1767 SCO3163 RV2632C/MT2708 4 76 3.0E-10 T 10-11-2016 IPR015057 Protein of unknown function DUF1876 A4G23_RS01240 5c2fc7f240c531143d27af3b79347090 100 Pfam PF08962 Domain of unknown function (DUF1876) 6 79 5.9E-29 T 10-11-2016 IPR015057 Protein of unknown function DUF1876 A4G23_RS01240 5c2fc7f240c531143d27af3b79347090 100 SUPERFAMILY SSF143212 3 79 1.57E-24 T 10-11-2016 A4G23_RS14035 caabc1587c7742843657b6b64fd6a59c 293 SUPERFAMILY SSF51735 5 255 1.71E-47 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS14035 caabc1587c7742843657b6b64fd6a59c 293 Gene3D G3DSA:3.40.50.720 2 220 7.9E-38 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS14035 caabc1587c7742843657b6b64fd6a59c 293 Pfam PF13460 NAD(P)H-binding 10 182 1.0E-21 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS02615 a892254d7c6dfc1db7dd2238e4988a3c 442 SUPERFAMILY SSF56176 364 435 7.63E-15 T 10-11-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 A4G23_RS02615 a892254d7c6dfc1db7dd2238e4988a3c 442 Gene3D G3DSA:3.10.580.10 209 330 9.9E-17 T 10-11-2016 A4G23_RS02615 a892254d7c6dfc1db7dd2238e4988a3c 442 Gene3D G3DSA:3.30.465.10 331 431 5.4E-21 T 10-11-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 A4G23_RS02615 a892254d7c6dfc1db7dd2238e4988a3c 442 Pfam PF03471 Transporter associated domain 364 431 1.2E-14 T 10-11-2016 IPR005170 Transporter-associated domain A4G23_RS02615 a892254d7c6dfc1db7dd2238e4988a3c 442 SMART SM01091 357 434 4.9E-15 T 10-11-2016 IPR005170 Transporter-associated domain A4G23_RS02615 a892254d7c6dfc1db7dd2238e4988a3c 442 SUPERFAMILY SSF54631 213 347 9.1E-26 T 10-11-2016 A4G23_RS02615 a892254d7c6dfc1db7dd2238e4988a3c 442 Pfam PF00571 CBS domain 288 335 2.1E-5 T 10-11-2016 IPR000644 CBS domain A4G23_RS02615 a892254d7c6dfc1db7dd2238e4988a3c 442 Pfam PF01595 Domain of unknown function DUF21 9 201 8.7E-33 T 10-11-2016 IPR002550 Domain of unknown function DUF21 A4G23_RS17205 23a312c247a27e101fdafe6fcdd76891 517 Gene3D G3DSA:3.40.140.20 364 507 2.4E-51 T 10-11-2016 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4G23_RS17205 23a312c247a27e101fdafe6fcdd76891 517 SUPERFAMILY SSF52335 7 195 1.68E-63 T 10-11-2016 IPR011607 Methylglyoxal synthase-like domain A4G23_RS17205 23a312c247a27e101fdafe6fcdd76891 517 SMART SM00851 19 133 7.5E-49 T 10-11-2016 IPR011607 Methylglyoxal synthase-like domain A4G23_RS17205 23a312c247a27e101fdafe6fcdd76891 517 PIRSF PIRSF000414 1 517 3.4E-196 T 10-11-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4G23_RS17205 23a312c247a27e101fdafe6fcdd76891 517 Pfam PF01808 AICARFT/IMPCHase bienzyme 138 450 2.3E-112 T 10-11-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4G23_RS17205 23a312c247a27e101fdafe6fcdd76891 517 Pfam PF02142 MGS-like domain 19 132 2.1E-23 T 10-11-2016 IPR011607 Methylglyoxal synthase-like domain A4G23_RS17205 23a312c247a27e101fdafe6fcdd76891 517 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 8 517 1.7E-171 T 10-11-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4G23_RS17205 23a312c247a27e101fdafe6fcdd76891 517 Gene3D G3DSA:3.40.50.1380 6 188 4.6E-76 T 10-11-2016 IPR011607 Methylglyoxal synthase-like domain A4G23_RS17205 23a312c247a27e101fdafe6fcdd76891 517 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 7 517 42.183 T 10-11-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4G23_RS17205 23a312c247a27e101fdafe6fcdd76891 517 SUPERFAMILY SSF53927 215 517 5.82E-118 T 10-11-2016 IPR016193 Cytidine deaminase-like GO:0003824 A4G23_RS17205 23a312c247a27e101fdafe6fcdd76891 517 SMART SM00798 138 451 2.1E-184 T 10-11-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4G23_RS17205 23a312c247a27e101fdafe6fcdd76891 517 Gene3D G3DSA:3.40.140.20 243 360 1.0E-45 T 10-11-2016 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4G23_RS24730 6db6c2d4c461fbc34dbd62cc83b9464a 397 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 13 140 9.9E-13 T 10-11-2016 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 A4G23_RS24730 6db6c2d4c461fbc34dbd62cc83b9464a 397 SUPERFAMILY SSF51735 11 165 2.27E-15 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS24730 6db6c2d4c461fbc34dbd62cc83b9464a 397 Gene3D G3DSA:3.40.50.720 13 176 2.5E-19 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS01785 b88c5e9b553666024d74b4bc6bb8986d 147 Gene3D G3DSA:3.30.530.20 5 140 3.0E-11 T 10-11-2016 IPR023393 START-like domain A4G23_RS01785 b88c5e9b553666024d74b4bc6bb8986d 147 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 8 140 1.1E-6 T 10-11-2016 IPR019587 Polyketide cyclase/dehydrase A4G23_RS01785 b88c5e9b553666024d74b4bc6bb8986d 147 SUPERFAMILY SSF55961 4 140 1.68E-14 T 10-11-2016 A4G23_RS23825 f896ed57659a9c18e3bf382d2522e0a6 591 Gene3D G3DSA:3.30.300.30 479 582 1.6E-23 T 10-11-2016 A4G23_RS23825 f896ed57659a9c18e3bf382d2522e0a6 591 Gene3D G3DSA:3.40.50.980 240 398 1.8E-26 T 10-11-2016 A4G23_RS23825 f896ed57659a9c18e3bf382d2522e0a6 591 Gene3D G3DSA:3.40.50.980 48 170 9.1E-26 T 10-11-2016 A4G23_RS23825 f896ed57659a9c18e3bf382d2522e0a6 591 Gene3D G3DSA:3.40.50.980 208 239 9.1E-26 T 10-11-2016 A4G23_RS23825 f896ed57659a9c18e3bf382d2522e0a6 591 Pfam PF00501 AMP-binding enzyme 48 481 1.6E-73 T 10-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A4G23_RS23825 f896ed57659a9c18e3bf382d2522e0a6 591 Pfam PF13193 AMP-binding enzyme C-terminal domain 490 567 5.9E-20 T 10-11-2016 IPR025110 AMP-binding enzyme C-terminal domain A4G23_RS23825 f896ed57659a9c18e3bf382d2522e0a6 591 Gene3D G3DSA:2.30.38.10 399 475 5.7E-18 T 10-11-2016 A4G23_RS23825 f896ed57659a9c18e3bf382d2522e0a6 591 SUPERFAMILY SSF56801 18 578 6.02E-132 T 10-11-2016 A4G23_RS13215 73b314d2c007e60daeee949ffbdf4fcc 373 SUPERFAMILY SSF51735 141 284 4.19E-28 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS13215 73b314d2c007e60daeee949ffbdf4fcc 373 Pfam PF02254 TrkA-N domain 146 262 9.2E-28 T 10-11-2016 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 A4G23_RS13215 73b314d2c007e60daeee949ffbdf4fcc 373 SUPERFAMILY SSF81324 40 163 5.23E-19 T 10-11-2016 A4G23_RS13215 73b314d2c007e60daeee949ffbdf4fcc 373 Pfam PF07885 Ion channel 43 124 5.5E-13 T 10-11-2016 IPR013099 Potassium channel domain A4G23_RS13215 73b314d2c007e60daeee949ffbdf4fcc 373 Gene3D G3DSA:3.40.50.720 140 277 1.0E-33 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS13215 73b314d2c007e60daeee949ffbdf4fcc 373 Gene3D G3DSA:1.10.287.70 41 134 2.5E-14 T 10-11-2016 A4G23_RS02135 0f978c6396585c68b62a3b9e15cfe34d 399 Pfam PF00534 Glycosyl transferases group 1 215 363 5.0E-25 T 10-11-2016 IPR001296 Glycosyl transferase, family 1 A4G23_RS02135 0f978c6396585c68b62a3b9e15cfe34d 399 SUPERFAMILY SSF53756 53 383 9.81E-65 T 10-11-2016 A4G23_RS02135 0f978c6396585c68b62a3b9e15cfe34d 399 Gene3D G3DSA:3.40.50.2000 212 363 9.3E-30 T 10-11-2016 A4G23_RS02135 0f978c6396585c68b62a3b9e15cfe34d 399 Pfam PF13439 Glycosyltransferase Family 4 53 205 2.4E-15 T 10-11-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A4G23_RS08485 0ec4a430e0850da6118b0c7478318010 413 Gene3D G3DSA:1.10.10.10 16 83 2.8E-13 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS08485 0ec4a430e0850da6118b0c7478318010 413 Pfam PF00480 ROK family 92 373 1.3E-23 T 10-11-2016 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A4G23_RS08485 0ec4a430e0850da6118b0c7478318010 413 Pfam PF12802 MarR family 22 67 1.3E-6 T 10-11-2016 A4G23_RS08485 0ec4a430e0850da6118b0c7478318010 413 SUPERFAMILY SSF53067 88 403 2.11E-36 T 10-11-2016 A4G23_RS08485 0ec4a430e0850da6118b0c7478318010 413 Gene3D G3DSA:3.30.420.40 84 226 3.0E-36 T 10-11-2016 A4G23_RS08485 0ec4a430e0850da6118b0c7478318010 413 SUPERFAMILY SSF46785 17 82 1.39E-11 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS08485 0ec4a430e0850da6118b0c7478318010 413 Gene3D G3DSA:3.30.420.40 227 380 1.6E-29 T 10-11-2016 A4G23_RS03250 63bb90abea4f570e4c20702c785526d1 454 Pfam PF11700 Vacuole effluxer Atg22 like 21 445 2.9E-87 T 10-11-2016 IPR024671 Autophagy-related protein 22-like A4G23_RS03250 63bb90abea4f570e4c20702c785526d1 454 Gene3D G3DSA:1.20.1250.20 257 439 4.4E-20 T 10-11-2016 A4G23_RS03250 63bb90abea4f570e4c20702c785526d1 454 Gene3D G3DSA:1.20.1250.20 36 221 2.9E-11 T 10-11-2016 A4G23_RS03250 63bb90abea4f570e4c20702c785526d1 454 SUPERFAMILY SSF103473 22 441 5.62E-40 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS23905 7bccd162dd9584b07d7b3ee62814d694 268 SUPERFAMILY SSF46785 22 92 1.44E-19 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS23905 7bccd162dd9584b07d7b3ee62814d694 268 SUPERFAMILY SSF55781 79 261 1.63E-51 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS23905 7bccd162dd9584b07d7b3ee62814d694 268 Pfam PF01614 Bacterial transcriptional regulator 137 259 3.9E-32 T 10-11-2016 IPR014757 Transcription regulator IclR, C-terminal A4G23_RS23905 7bccd162dd9584b07d7b3ee62814d694 268 Gene3D G3DSA:3.30.450.40 96 262 1.8E-61 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS23905 7bccd162dd9584b07d7b3ee62814d694 268 Gene3D G3DSA:1.10.10.10 20 94 1.3E-26 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS23905 7bccd162dd9584b07d7b3ee62814d694 268 Pfam PF09339 IclR helix-turn-helix domain 24 75 2.7E-18 T 10-11-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4G23_RS23905 7bccd162dd9584b07d7b3ee62814d694 268 SMART SM00346 22 109 7.4E-23 T 10-11-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4G23_RS18475 6b185cb558fedd4569498476138b8a15 296 SUPERFAMILY SSF102588 7 293 3.66E-72 T 10-11-2016 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 A4G23_RS18475 6b185cb558fedd4569498476138b8a15 296 TIGRFAM TIGR03445 mycothiol_MshB: N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase 10 294 1.2E-120 T 10-11-2016 IPR017810 Mycothiol biosynthesis protein, MshB GO:0035595 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 A4G23_RS18475 6b185cb558fedd4569498476138b8a15 296 Hamap MF_01696 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase [mshB]. 9 294 39.881 T 10-11-2016 IPR017810 Mycothiol biosynthesis protein, MshB GO:0035595 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 A4G23_RS18475 6b185cb558fedd4569498476138b8a15 296 Pfam PF02585 GlcNAc-PI de-N-acetylase 10 160 8.9E-25 T 10-11-2016 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 A4G23_RS18475 6b185cb558fedd4569498476138b8a15 296 Gene3D G3DSA:3.40.50.10320 6 295 1.9E-91 T 10-11-2016 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 A4G23_RS12830 a2aad3cc8628d0d2df41997b8c85e651 246 Pfam PF13462 Thioredoxin 74 239 3.0E-29 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS12830 a2aad3cc8628d0d2df41997b8c85e651 246 Gene3D G3DSA:3.40.30.10 72 243 2.1E-44 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS12830 a2aad3cc8628d0d2df41997b8c85e651 246 SUPERFAMILY SSF52833 65 238 1.6E-39 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS27210 de57e7d08c57eb3e57fd4b325f66bce7 412 PRINTS PR00359 B-class P450 signature 97 108 7.1E-39 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS27210 de57e7d08c57eb3e57fd4b325f66bce7 412 PRINTS PR00359 B-class P450 signature 301 328 7.1E-39 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS27210 de57e7d08c57eb3e57fd4b325f66bce7 412 PRINTS PR00359 B-class P450 signature 350 359 7.1E-39 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS27210 de57e7d08c57eb3e57fd4b325f66bce7 412 PRINTS PR00359 B-class P450 signature 203 225 7.1E-39 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS27210 de57e7d08c57eb3e57fd4b325f66bce7 412 PRINTS PR00359 B-class P450 signature 284 295 7.1E-39 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS27210 de57e7d08c57eb3e57fd4b325f66bce7 412 PRINTS PR00359 B-class P450 signature 359 370 7.1E-39 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS27210 de57e7d08c57eb3e57fd4b325f66bce7 412 PRINTS PR00359 B-class P450 signature 159 174 7.1E-39 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS27210 de57e7d08c57eb3e57fd4b325f66bce7 412 PRINTS PR00359 B-class P450 signature 329 344 7.1E-39 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS27210 de57e7d08c57eb3e57fd4b325f66bce7 412 Pfam PF00067 Cytochrome P450 218 377 5.6E-20 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS27210 de57e7d08c57eb3e57fd4b325f66bce7 412 Gene3D G3DSA:1.10.630.10 10 411 9.3E-104 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS27210 de57e7d08c57eb3e57fd4b325f66bce7 412 SUPERFAMILY SSF48264 25 410 2.88E-82 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS27210 de57e7d08c57eb3e57fd4b325f66bce7 412 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 352 361 - T 10-11-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A4G23_RS01040 6dc33d833b851e056181b5a6a02902da 318 Gene3D G3DSA:3.40.50.2000 4 142 3.5E-10 T 10-11-2016 A4G23_RS01040 6dc33d833b851e056181b5a6a02902da 318 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 159 270 2.8E-22 T 10-11-2016 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 A4G23_RS01040 6dc33d833b851e056181b5a6a02902da 318 SUPERFAMILY SSF53756 4 314 4.71E-59 T 10-11-2016 A4G23_RS01040 6dc33d833b851e056181b5a6a02902da 318 Gene3D G3DSA:3.40.50.2000 145 314 5.0E-43 T 10-11-2016 A4G23_RS24150 6655df51e439a68c5812cd5d7d0f6466 255 Pfam PF00583 Acetyltransferase (GNAT) family 184 242 3.1E-5 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS24150 6655df51e439a68c5812cd5d7d0f6466 255 Gene3D G3DSA:3.40.630.30 125 248 5.5E-12 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS24150 6655df51e439a68c5812cd5d7d0f6466 255 SUPERFAMILY SSF55729 81 252 2.05E-14 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS09265 abb9758819083aa880729a333646d70b 259 SUPERFAMILY SSF52540 18 254 3.03E-80 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS09265 abb9758819083aa880729a333646d70b 259 Pfam PF00005 ABC transporter 34 183 5.8E-37 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS09265 abb9758819083aa880729a333646d70b 259 PIRSF PIRSF039085 15 259 1.4E-96 T 10-11-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 A4G23_RS09265 abb9758819083aa880729a333646d70b 259 Gene3D G3DSA:3.40.50.300 18 256 1.3E-86 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS09265 abb9758819083aa880729a333646d70b 259 TIGRFAM TIGR03005 ectoine_ehuA: ectoine/hydroxyectoine ABC transporter, ATP-binding protein EhuA 19 258 3.2E-107 T 10-11-2016 IPR014343 Ectoine/hydroxyectoine ABC transporter, ATP-binding protein A4G23_RS09265 abb9758819083aa880729a333646d70b 259 SMART SM00382 43 232 2.0E-20 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS09265 abb9758819083aa880729a333646d70b 259 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS21415 c6166a43648ce7fd28b0e540e4fdce7c 454 Pfam PF05193 Peptidase M16 inactive domain 185 364 6.7E-29 T 10-11-2016 IPR007863 Peptidase M16, C-terminal A4G23_RS21415 c6166a43648ce7fd28b0e540e4fdce7c 454 Gene3D G3DSA:3.30.830.10 18 235 2.8E-60 T 10-11-2016 IPR011237 Peptidase M16 domain GO:0046872 A4G23_RS21415 c6166a43648ce7fd28b0e540e4fdce7c 454 Pfam PF00675 Insulinase (Peptidase family M16) 26 145 1.1E-21 T 10-11-2016 IPR011765 Peptidase M16, N-terminal A4G23_RS21415 c6166a43648ce7fd28b0e540e4fdce7c 454 Gene3D G3DSA:3.30.830.10 275 427 2.1E-17 T 10-11-2016 IPR011237 Peptidase M16 domain GO:0046872 A4G23_RS21415 c6166a43648ce7fd28b0e540e4fdce7c 454 SUPERFAMILY SSF63411 249 433 1.32E-27 T 10-11-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A4G23_RS21415 c6166a43648ce7fd28b0e540e4fdce7c 454 SUPERFAMILY SSF63411 16 230 1.45E-60 T 10-11-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A4G23_RS11425 b8a13663dec39b977e80831c750ccb6e 132 Gene3D G3DSA:3.30.750.24 2 116 3.6E-35 T 10-11-2016 IPR002645 STAS domain A4G23_RS11425 b8a13663dec39b977e80831c750ccb6e 132 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 3 110 1.4E-17 T 10-11-2016 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 A4G23_RS11425 b8a13663dec39b977e80831c750ccb6e 132 SUPERFAMILY SSF52091 3 113 4.32E-21 T 10-11-2016 IPR002645 STAS domain A4G23_RS11425 b8a13663dec39b977e80831c750ccb6e 132 Pfam PF01740 STAS domain 10 80 5.2E-13 T 10-11-2016 IPR002645 STAS domain A4G23_RS19420 07fcfe0deaf1c36a8c8b8e5463cfff4a 482 SUPERFAMILY SSF53300 18 191 3.71E-22 T 10-11-2016 IPR002035 von Willebrand factor, type A A4G23_RS19420 07fcfe0deaf1c36a8c8b8e5463cfff4a 482 Pfam PF13768 von Willebrand factor type A domain 18 173 7.2E-13 T 10-11-2016 IPR002035 von Willebrand factor, type A A4G23_RS19420 07fcfe0deaf1c36a8c8b8e5463cfff4a 482 SMART SM00327 14 195 4.0E-10 T 10-11-2016 IPR002035 von Willebrand factor, type A A4G23_RS19420 07fcfe0deaf1c36a8c8b8e5463cfff4a 482 Gene3D G3DSA:3.40.50.410 18 182 5.0E-9 T 10-11-2016 IPR002035 von Willebrand factor, type A A4G23_RS13705 2ef4efa9d7ad0dbc538d7c78f4183c85 361 Pfam PF00155 Aminotransferase class I and II 34 342 2.2E-52 T 10-11-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4G23_RS13705 2ef4efa9d7ad0dbc538d7c78f4183c85 361 SUPERFAMILY SSF53383 15 351 1.86E-78 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS13705 2ef4efa9d7ad0dbc538d7c78f4183c85 361 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 10 352 3.0E-88 T 10-11-2016 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 A4G23_RS13705 2ef4efa9d7ad0dbc538d7c78f4183c85 361 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 221 230 - T 10-11-2016 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 A4G23_RS13705 2ef4efa9d7ad0dbc538d7c78f4183c85 361 Gene3D G3DSA:3.40.640.10 48 245 2.4E-48 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS13705 2ef4efa9d7ad0dbc538d7c78f4183c85 361 Hamap MF_01513 Putative phenylalanine aminotransferase [pat]. 8 358 49.294 T 10-11-2016 IPR024892 Putative phenylalanine aminotransferase A4G23_RS13705 2ef4efa9d7ad0dbc538d7c78f4183c85 361 Gene3D G3DSA:3.90.1150.10 246 355 5.3E-28 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS13705 2ef4efa9d7ad0dbc538d7c78f4183c85 361 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 7 357 50.919 T 10-11-2016 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 A4G23_RS02095 c1f046128e1a0d41510c907a0e96629d 504 SUPERFAMILY SSF161098 9 239 1.96E-42 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS02095 c1f046128e1a0d41510c907a0e96629d 504 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 328 494 1.2E-13 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS02095 c1f046128e1a0d41510c907a0e96629d 504 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 72 234 9.0E-15 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS02095 c1f046128e1a0d41510c907a0e96629d 504 SUPERFAMILY SSF161098 264 501 1.31E-34 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS02095 c1f046128e1a0d41510c907a0e96629d 504 Gene3D G3DSA:1.10.3720.10 11 244 6.1E-41 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS02095 c1f046128e1a0d41510c907a0e96629d 504 Gene3D G3DSA:1.10.3720.10 303 502 8.5E-27 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS10865 4cfab9bf18adb42f78ef474c17d4d789 207 Gene3D G3DSA:3.40.630.30 2 191 8.0E-60 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS10865 4cfab9bf18adb42f78ef474c17d4d789 207 SUPERFAMILY SSF55729 6 185 1.06E-41 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS10865 4cfab9bf18adb42f78ef474c17d4d789 207 Pfam PF13302 Acetyltransferase (GNAT) domain 14 161 7.9E-17 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS06090 a1847227544eac6d78cf8f14aed932a8 165 Gene3D G3DSA:3.90.960.10 9 163 2.0E-60 T 10-11-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 A4G23_RS06090 a1847227544eac6d78cf8f14aed932a8 165 Pfam PF04073 Aminoacyl-tRNA editing domain 41 153 1.0E-28 T 10-11-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 A4G23_RS06090 a1847227544eac6d78cf8f14aed932a8 165 PIRSF PIRSF006181 7 165 3.6E-53 T 10-11-2016 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC A4G23_RS06090 a1847227544eac6d78cf8f14aed932a8 165 SUPERFAMILY SSF55826 12 162 1.57E-44 T 10-11-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 A4G23_RS06090 a1847227544eac6d78cf8f14aed932a8 165 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 12 162 3.0E-55 T 10-11-2016 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC A4G23_RS11400 1087937954470d1eb71fa8686ab5aeac 390 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 138 156 5.6E-10 T 10-11-2016 A4G23_RS11400 1087937954470d1eb71fa8686ab5aeac 390 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 182 200 5.6E-10 T 10-11-2016 A4G23_RS11400 1087937954470d1eb71fa8686ab5aeac 390 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 20 39 5.6E-10 T 10-11-2016 A4G23_RS11400 1087937954470d1eb71fa8686ab5aeac 390 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 178 202 6.5E-13 T 10-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4G23_RS11400 1087937954470d1eb71fa8686ab5aeac 390 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 19 41 6.5E-13 T 10-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4G23_RS11400 1087937954470d1eb71fa8686ab5aeac 390 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 139 147 6.5E-13 T 10-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4G23_RS11400 1087937954470d1eb71fa8686ab5aeac 390 SUPERFAMILY SSF51905 20 225 2.37E-40 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS11400 1087937954470d1eb71fa8686ab5aeac 390 Gene3D G3DSA:3.50.50.60 7 218 1.2E-44 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS11400 1087937954470d1eb71fa8686ab5aeac 390 SUPERFAMILY SSF51905 181 390 3.63E-8 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS11400 1087937954470d1eb71fa8686ab5aeac 390 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 22 215 3.0E-27 T 10-11-2016 A4G23_RS23990 fb998c40959b98c63ba00335c4c59ef0 434 Pfam PF00999 Sodium/hydrogen exchanger family 18 408 1.9E-55 T 10-11-2016 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A4G23_RS03860 806748765a8236d8d63572f49829c408 351 SUPERFAMILY SSF56322 57 337 1.83E-88 T 10-11-2016 IPR005801 ADC synthase GO:0009058 A4G23_RS03860 806748765a8236d8d63572f49829c408 351 PRINTS PR00095 Anthranilate synthase component I signature 187 200 4.9E-9 T 10-11-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A4G23_RS03860 806748765a8236d8d63572f49829c408 351 PRINTS PR00095 Anthranilate synthase component I signature 267 281 4.9E-9 T 10-11-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A4G23_RS03860 806748765a8236d8d63572f49829c408 351 PRINTS PR00095 Anthranilate synthase component I signature 283 297 4.9E-9 T 10-11-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A4G23_RS03860 806748765a8236d8d63572f49829c408 351 Pfam PF00425 chorismate binding enzyme 79 330 7.0E-70 T 10-11-2016 IPR015890 Chorismate-utilising enzyme, C-terminal A4G23_RS03860 806748765a8236d8d63572f49829c408 351 Gene3D G3DSA:3.60.120.10 68 337 2.1E-96 T 10-11-2016 IPR005801 ADC synthase GO:0009058 A4G23_RS16865 a2ba1cda460ed8cc0ad8abe7fa451835 384 Gene3D G3DSA:3.40.50.1820 74 368 4.1E-61 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS16865 a2ba1cda460ed8cc0ad8abe7fa451835 384 Pfam PF00561 alpha/beta hydrolase fold 100 355 2.2E-23 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS16865 a2ba1cda460ed8cc0ad8abe7fa451835 384 SUPERFAMILY SSF53474 75 367 6.03E-56 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS25100 76043b382bf3e41069678ae3baab1fe8 336 Pfam PF00355 Rieske [2Fe-2S] domain 51 121 1.5E-11 T 10-11-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A4G23_RS25100 76043b382bf3e41069678ae3baab1fe8 336 Gene3D G3DSA:2.102.10.10 51 146 4.4E-16 T 10-11-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A4G23_RS25100 76043b382bf3e41069678ae3baab1fe8 336 SUPERFAMILY SSF50022 49 145 1.19E-19 T 10-11-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A4G23_RS10455 ca51208c43d71dd2c39adf294a1a798c 764 SUPERFAMILY SSF53335 204 490 3.53E-46 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS10455 ca51208c43d71dd2c39adf294a1a798c 764 SUPERFAMILY SSF116734 636 755 3.27E-6 T 10-11-2016 A4G23_RS10455 ca51208c43d71dd2c39adf294a1a798c 764 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 309 321 1.2E-11 T 10-11-2016 A4G23_RS10455 ca51208c43d71dd2c39adf294a1a798c 764 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 246 260 1.2E-11 T 10-11-2016 A4G23_RS10455 ca51208c43d71dd2c39adf294a1a798c 764 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 343 367 1.2E-11 T 10-11-2016 A4G23_RS10455 ca51208c43d71dd2c39adf294a1a798c 764 Gene3D G3DSA:3.40.50.150 218 398 8.1E-27 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS10455 ca51208c43d71dd2c39adf294a1a798c 764 Pfam PF02384 N-6 DNA Methylase 204 430 9.7E-29 T 10-11-2016 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 A4G23_RS10520 4d0a52fc9649976c898b73f48bc0f131 329 Pfam PF09346 SMI1 / KNR4 family (SUKH-1) 161 296 1.3E-8 T 10-11-2016 IPR018958 SMI1/KNR4-like domain A4G23_RS10520 4d0a52fc9649976c898b73f48bc0f131 329 Gene3D G3DSA:3.40.1580.10 160 193 6.9E-6 T 10-11-2016 IPR018958 SMI1/KNR4-like domain A4G23_RS10520 4d0a52fc9649976c898b73f48bc0f131 329 Pfam PF14414 A nuclease of the HNH/ENDO VII superfamily with conserved WHH 96 131 4.3E-13 T 10-11-2016 IPR032869 WHH domain-containing protein A4G23_RS10520 4d0a52fc9649976c898b73f48bc0f131 329 SMART SM00860 160 297 2.0E-4 T 10-11-2016 IPR018958 SMI1/KNR4-like domain A4G23_RS10520 4d0a52fc9649976c898b73f48bc0f131 329 SUPERFAMILY SSF160631 155 297 1.09E-15 T 10-11-2016 A4G23_RS05460 c304ea35cf5d243fe4a831de5578225c 566 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 117 127 - T 10-11-2016 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A4G23_RS05460 c304ea35cf5d243fe4a831de5578225c 566 SUPERFAMILY SSF143975 2 368 8.5E-122 T 10-11-2016 A4G23_RS05460 c304ea35cf5d243fe4a831de5578225c 566 SUPERFAMILY SSF52016 369 553 2.75E-58 T 10-11-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel A4G23_RS05460 c304ea35cf5d243fe4a831de5578225c 566 Pfam PF00920 Dehydratase family 34 549 7.5E-175 T 10-11-2016 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A4G23_RS14205 5a4d699c23234b17839c12acc2a0779b 67 SMART SM00357 3 67 3.9E-30 T 10-11-2016 IPR011129 Cold shock protein GO:0003676 A4G23_RS14205 5a4d699c23234b17839c12acc2a0779b 67 PRINTS PR00050 Cold shock protein signature 4 19 2.4E-17 T 10-11-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4G23_RS14205 5a4d699c23234b17839c12acc2a0779b 67 PRINTS PR00050 Cold shock protein signature 25 34 2.4E-17 T 10-11-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4G23_RS14205 5a4d699c23234b17839c12acc2a0779b 67 PRINTS PR00050 Cold shock protein signature 40 58 2.4E-17 T 10-11-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4G23_RS14205 5a4d699c23234b17839c12acc2a0779b 67 SUPERFAMILY SSF50249 1 65 4.29E-25 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS14205 5a4d699c23234b17839c12acc2a0779b 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 10-11-2016 IPR019844 Cold-shock conserved site A4G23_RS14205 5a4d699c23234b17839c12acc2a0779b 67 PIRSF PIRSF002599 1 67 8.4E-26 T 10-11-2016 IPR012156 Cold shock, CspA GO:0003676 A4G23_RS14205 5a4d699c23234b17839c12acc2a0779b 67 Gene3D G3DSA:2.40.50.140 1 64 2.2E-30 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS14205 5a4d699c23234b17839c12acc2a0779b 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 8.2E-31 T 10-11-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4G23_RS15490 f6b8d90f792b42ffd283ed8e851b1cda 699 Gene3D G3DSA:1.10.1740.10 47 122 5.0E-5 T 10-11-2016 A4G23_RS23340 aa889f7c03d64ed9319a4b212aef90fb 134 Pfam PF07498 Rho termination factor, N-terminal domain 96 123 1.9E-6 T 10-11-2016 IPR011112 Rho termination factor, N-terminal GO:0006353 A4G23_RS23340 aa889f7c03d64ed9319a4b212aef90fb 134 Pfam PF06150 ChaB 7 61 1.2E-17 T 10-11-2016 IPR009317 ChaB A4G23_RS23340 aa889f7c03d64ed9319a4b212aef90fb 134 SUPERFAMILY SSF140376 3 61 1.07E-15 T 10-11-2016 A4G23_RS07890 4bffc21ed78ec7599b366fc0374a1900 311 SUPERFAMILY SSF52540 93 278 6.44E-41 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS07890 4bffc21ed78ec7599b366fc0374a1900 311 Pfam PF02562 PhoH-like protein 100 303 5.0E-95 T 10-11-2016 IPR003714 PhoH-like protein GO:0005524 A4G23_RS07890 4bffc21ed78ec7599b366fc0374a1900 311 Gene3D G3DSA:3.40.50.300 99 303 1.3E-102 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS20740 80980e53e5afe551cf93348a5d69ba38 400 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 35 136 2.4E-11 T 10-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 A4G23_RS20740 80980e53e5afe551cf93348a5d69ba38 400 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 140 234 3.1E-18 T 10-11-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 A4G23_RS20740 80980e53e5afe551cf93348a5d69ba38 400 Gene3D G3DSA:1.10.540.10 35 136 1.2E-13 T 10-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 A4G23_RS20740 80980e53e5afe551cf93348a5d69ba38 400 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 246 394 7.3E-30 T 10-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4G23_RS20740 80980e53e5afe551cf93348a5d69ba38 400 SUPERFAMILY SSF56645 35 246 5.5E-50 T 10-11-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 A4G23_RS20740 80980e53e5afe551cf93348a5d69ba38 400 Gene3D G3DSA:1.20.140.10 235 399 3.8E-37 T 10-11-2016 A4G23_RS20740 80980e53e5afe551cf93348a5d69ba38 400 SUPERFAMILY SSF47203 245 399 1.51E-29 T 10-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4G23_RS20740 80980e53e5afe551cf93348a5d69ba38 400 Gene3D G3DSA:2.40.110.10 140 234 4.3E-27 T 10-11-2016 A4G23_RS18820 ccf46273d694d484f274a6a3a6e72fcc 251 SUPERFAMILY SSF51219 17 224 4.19E-41 T 10-11-2016 IPR016031 Tryptophan RNA-binding attenuator protein-like domain A4G23_RS18820 ccf46273d694d484f274a6a3a6e72fcc 251 Pfam PF01987 Mitochondrial biogenesis AIM24 21 215 3.9E-29 T 10-11-2016 IPR002838 Mitochondrial biogenesis protein AIM24 A4G23_RS18820 ccf46273d694d484f274a6a3a6e72fcc 251 Gene3D G3DSA:3.60.160.10 13 219 8.0E-35 T 10-11-2016 IPR002838 Mitochondrial biogenesis protein AIM24 A4G23_RS05335 9a9e48efbe4be4d85ab08aa363817c6b 187 SUPERFAMILY SSF55729 15 187 4.16E-34 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS05335 9a9e48efbe4be4d85ab08aa363817c6b 187 Gene3D G3DSA:3.40.630.30 6 187 7.0E-44 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS05335 9a9e48efbe4be4d85ab08aa363817c6b 187 Pfam PF13523 Acetyltransferase (GNAT) domain 23 164 4.6E-45 T 10-11-2016 A4G23_RS05335 9a9e48efbe4be4d85ab08aa363817c6b 187 SMART SM01006 20 68 8.9E-14 T 10-11-2016 IPR019432 Siderophore biosynthesis protein, conserved domain A4G23_RS23535 f8fdd3d2481d7d634e5f5f98ec0a3b61 615 Pfam PF04183 IucA / IucC family 165 412 2.9E-75 T 10-11-2016 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0015343|GO:0019290 A4G23_RS23535 f8fdd3d2481d7d634e5f5f98ec0a3b61 615 Pfam PF06276 Ferric iron reductase FhuF-like transporter 435 586 3.0E-34 T 10-11-2016 IPR022770 Ferric iron reductase FhuF domain A4G23_RS07495 81872cb5a6092416640b1643d31641d8 307 SUPERFAMILY SSF52151 2 116 7.06E-65 T 10-11-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 A4G23_RS07495 81872cb5a6092416640b1643d31641d8 307 SUPERFAMILY SSF52151 179 302 7.06E-65 T 10-11-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 A4G23_RS07495 81872cb5a6092416640b1643d31641d8 307 Gene3D G3DSA:3.40.366.10 2 116 5.3E-53 T 10-11-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 A4G23_RS07495 81872cb5a6092416640b1643d31641d8 307 Gene3D G3DSA:3.40.366.10 186 293 5.3E-53 T 10-11-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 A4G23_RS07495 81872cb5a6092416640b1643d31641d8 307 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5 305 5.3E-18 T 10-11-2016 IPR020801 Polyketide synthase, acyl transferase domain A4G23_RS07495 81872cb5a6092416640b1643d31641d8 307 Gene3D G3DSA:3.30.70.250 121 185 6.1E-22 T 10-11-2016 A4G23_RS07495 81872cb5a6092416640b1643d31641d8 307 Pfam PF00698 Acyl transferase domain 5 278 4.5E-20 T 10-11-2016 IPR014043 Acyl transferase A4G23_RS07495 81872cb5a6092416640b1643d31641d8 307 SUPERFAMILY SSF55048 124 177 1.19E-10 T 10-11-2016 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 A4G23_RS22910 873f2de502c7cfa7a8002365830d09c5 709 SUPERFAMILY SSF52096 253 327 7.33E-34 T 10-11-2016 IPR029045 ClpP/crotonase-like domain A4G23_RS22910 873f2de502c7cfa7a8002365830d09c5 709 SUPERFAMILY SSF52096 34 220 7.33E-34 T 10-11-2016 IPR029045 ClpP/crotonase-like domain A4G23_RS22910 873f2de502c7cfa7a8002365830d09c5 709 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 524 606 8.7E-12 T 10-11-2016 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 A4G23_RS22910 873f2de502c7cfa7a8002365830d09c5 709 Gene3D G3DSA:3.90.226.10 35 238 1.1E-35 T 10-11-2016 IPR029045 ClpP/crotonase-like domain A4G23_RS22910 873f2de502c7cfa7a8002365830d09c5 709 Gene3D G3DSA:1.10.1040.10 526 611 8.2E-11 T 10-11-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A4G23_RS22910 873f2de502c7cfa7a8002365830d09c5 709 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 340 520 4.9E-58 T 10-11-2016 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 A4G23_RS22910 873f2de502c7cfa7a8002365830d09c5 709 SUPERFAMILY SSF51735 338 522 3.69E-52 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS22910 873f2de502c7cfa7a8002365830d09c5 709 SUPERFAMILY SSF48179 634 694 4.85E-10 T 10-11-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A4G23_RS22910 873f2de502c7cfa7a8002365830d09c5 709 Gene3D G3DSA:3.40.50.720 335 525 4.7E-55 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS22910 873f2de502c7cfa7a8002365830d09c5 709 Pfam PF00378 Enoyl-CoA hydratase/isomerase 53 236 5.3E-19 T 10-11-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 A4G23_RS22910 873f2de502c7cfa7a8002365830d09c5 709 SUPERFAMILY SSF48179 522 615 1.79E-17 T 10-11-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A4G23_RS01825 918869333a1116a78a9648e1aa61c4f9 410 Gene3D G3DSA:1.10.10.10 23 83 3.0E-6 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS01825 918869333a1116a78a9648e1aa61c4f9 410 Gene3D G3DSA:3.30.420.40 231 378 2.2E-33 T 10-11-2016 A4G23_RS01825 918869333a1116a78a9648e1aa61c4f9 410 Pfam PF00480 ROK family 100 391 8.5E-33 T 10-11-2016 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A4G23_RS01825 918869333a1116a78a9648e1aa61c4f9 410 Gene3D G3DSA:3.30.420.40 86 230 4.5E-25 T 10-11-2016 A4G23_RS01825 918869333a1116a78a9648e1aa61c4f9 410 SUPERFAMILY SSF53067 88 216 3.5E-15 T 10-11-2016 A4G23_RS01825 918869333a1116a78a9648e1aa61c4f9 410 SUPERFAMILY SSF53067 224 400 5.28E-32 T 10-11-2016 A4G23_RS26635 1022bdca5d1a9b9661e2a363ee2f526d 471 Pfam PF01425 Amidase 26 450 1.7E-96 T 10-11-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4G23_RS26635 1022bdca5d1a9b9661e2a363ee2f526d 471 SUPERFAMILY SSF75304 5 467 6.67E-119 T 10-11-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4G23_RS26635 1022bdca5d1a9b9661e2a363ee2f526d 471 Gene3D G3DSA:3.90.1300.10 4 463 6.2E-123 T 10-11-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4G23_RS26635 1022bdca5d1a9b9661e2a363ee2f526d 471 ProSitePatterns PS00571 Amidases signature. 155 186 - T 10-11-2016 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 A4G23_RS04670 73d88840a5d7cc723035510370a78b0c 442 Pfam PF04209 homogentisate 1,2-dioxygenase 19 440 2.5E-211 T 10-11-2016 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|Reactome: R-HSA-71182 A4G23_RS04670 73d88840a5d7cc723035510370a78b0c 442 Gene3D G3DSA:2.60.120.10 207 232 2.6E-7 T 10-11-2016 IPR014710 RmlC-like jelly roll fold A4G23_RS04670 73d88840a5d7cc723035510370a78b0c 442 Gene3D G3DSA:2.60.120.10 256 410 2.8E-62 T 10-11-2016 IPR014710 RmlC-like jelly roll fold A4G23_RS04670 73d88840a5d7cc723035510370a78b0c 442 TIGRFAM TIGR01015 hmgA: homogentisate 1,2-dioxygenase 18 440 1.5E-216 T 10-11-2016 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|Reactome: R-HSA-71182 A4G23_RS04670 73d88840a5d7cc723035510370a78b0c 442 SUPERFAMILY SSF51182 18 442 1.26E-162 T 10-11-2016 IPR011051 RmlC-like cupin domain A4G23_RS04670 73d88840a5d7cc723035510370a78b0c 442 Hamap MF_00334 Homogentisate 1,2-dioxygenase [hmgA]. 19 442 71.991 T 10-11-2016 IPR022950 Homogentisate 1,2-dioxygenase, bacterial GO:0004411|GO:0006559|GO:0006572|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5 A4G23_RS19705 a5808a19647a720a235533338bf93987 216 Gene3D G3DSA:3.60.160.10 8 211 1.8E-43 T 10-11-2016 IPR002838 Mitochondrial biogenesis protein AIM24 A4G23_RS19705 a5808a19647a720a235533338bf93987 216 Pfam PF01987 Mitochondrial biogenesis AIM24 7 211 1.4E-33 T 10-11-2016 IPR002838 Mitochondrial biogenesis protein AIM24 A4G23_RS19705 a5808a19647a720a235533338bf93987 216 SUPERFAMILY SSF51219 7 213 5.75E-46 T 10-11-2016 IPR016031 Tryptophan RNA-binding attenuator protein-like domain A4G23_RS12155 37ddb56defa5a62f545d5bb3184c0dba 316 Gene3D G3DSA:3.30.1330.30 70 147 9.6E-19 T 10-11-2016 IPR029064 50S ribosomal protein L30e-like A4G23_RS12155 37ddb56defa5a62f545d5bb3184c0dba 316 Gene3D G3DSA:3.40.1280.10 163 315 1.5E-48 T 10-11-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A4G23_RS12155 37ddb56defa5a62f545d5bb3184c0dba 316 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 72 315 3.3E-58 T 10-11-2016 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 A4G23_RS12155 37ddb56defa5a62f545d5bb3184c0dba 316 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 75 151 7.3E-19 T 10-11-2016 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 A4G23_RS12155 37ddb56defa5a62f545d5bb3184c0dba 316 SUPERFAMILY SSF75217 139 315 2.75E-42 T 10-11-2016 IPR029028 Alpha/beta knot methyltransferases A4G23_RS12155 37ddb56defa5a62f545d5bb3184c0dba 316 SUPERFAMILY SSF55315 69 148 1.65E-14 T 10-11-2016 IPR029064 50S ribosomal protein L30e-like A4G23_RS12155 37ddb56defa5a62f545d5bb3184c0dba 316 Pfam PF00588 SpoU rRNA Methylase family 168 309 5.9E-34 T 10-11-2016 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 A4G23_RS12155 37ddb56defa5a62f545d5bb3184c0dba 316 SMART SM00967 74 151 1.1E-19 T 10-11-2016 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 A4G23_RS12395 d1a41aa6291740e0124dfdef8e76e7e3 149 Pfam PF01475 Ferric uptake regulator family 13 121 1.5E-24 T 10-11-2016 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 A4G23_RS12395 d1a41aa6291740e0124dfdef8e76e7e3 149 SUPERFAMILY SSF46785 6 134 5.24E-33 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS12395 d1a41aa6291740e0124dfdef8e76e7e3 149 Gene3D G3DSA:1.10.10.10 5 82 3.6E-21 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS14005 838e9b5f30166544e8dc0c042b2aec13 376 Gene3D G3DSA:3.30.2110.10 25 197 1.8E-58 T 10-11-2016 A4G23_RS14005 838e9b5f30166544e8dc0c042b2aec13 376 Pfam PF01888 CbiD 22 282 9.4E-89 T 10-11-2016 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 A4G23_RS14005 838e9b5f30166544e8dc0c042b2aec13 376 SUPERFAMILY SSF111342 16 299 2.62E-82 T 10-11-2016 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 A4G23_RS14005 838e9b5f30166544e8dc0c042b2aec13 376 TIGRFAM TIGR00312 cbiD: cobalamin biosynthesis protein CbiD 29 333 8.9E-53 T 10-11-2016 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 A4G23_RS14005 838e9b5f30166544e8dc0c042b2aec13 376 Hamap MF_00787 Cobalt-precorrin-5B C(1)-methyltransferase [cbiD]. 22 373 27.695 T 10-11-2016 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 A4G23_RS14005 838e9b5f30166544e8dc0c042b2aec13 376 PIRSF PIRSF026782 18 376 9.8E-127 T 10-11-2016 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 A4G23_RS03525 be4a71a5bcb78870d5f6562c1baab1b0 197 Gene3D G3DSA:3.40.50.300 99 194 2.7E-39 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS03525 be4a71a5bcb78870d5f6562c1baab1b0 197 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 18 194 6.2E-69 T 10-11-2016 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 A4G23_RS03525 be4a71a5bcb78870d5f6562c1baab1b0 197 SMART SM00072 16 197 4.6E-59 T 10-11-2016 IPR008145 Guanylate kinase/L-type calcium channel beta subunit A4G23_RS03525 be4a71a5bcb78870d5f6562c1baab1b0 197 Gene3D G3DSA:3.40.1140.10 14 62 9.8E-5 T 10-11-2016 A4G23_RS03525 be4a71a5bcb78870d5f6562c1baab1b0 197 ProSitePatterns PS00856 Guanylate kinase-like signature. 51 68 - T 10-11-2016 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 A4G23_RS03525 be4a71a5bcb78870d5f6562c1baab1b0 197 Pfam PF00625 Guanylate kinase 17 194 1.1E-43 T 10-11-2016 IPR008145 Guanylate kinase/L-type calcium channel beta subunit A4G23_RS03525 be4a71a5bcb78870d5f6562c1baab1b0 197 Hamap MF_00328 Guanylate kinase [gmk]. 15 197 33.958 T 10-11-2016 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 A4G23_RS03525 be4a71a5bcb78870d5f6562c1baab1b0 197 SUPERFAMILY SSF52540 14 195 2.67E-61 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS03525 be4a71a5bcb78870d5f6562c1baab1b0 197 Gene3D G3DSA:3.30.63.10 63 98 2.4E-26 T 10-11-2016 A4G23_RS09500 d098f90093e15a07fe16624186709965 813 SUPERFAMILY SSF55486 354 435 2.45E-16 T 10-11-2016 A4G23_RS09500 d098f90093e15a07fe16624186709965 813 SUPERFAMILY SSF55486 241 300 2.45E-16 T 10-11-2016 A4G23_RS09500 d098f90093e15a07fe16624186709965 813 Gene3D G3DSA:3.40.390.10 241 291 1.6E-26 T 10-11-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 A4G23_RS09500 d098f90093e15a07fe16624186709965 813 Gene3D G3DSA:3.40.390.10 354 435 1.6E-26 T 10-11-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 A4G23_RS09500 d098f90093e15a07fe16624186709965 813 PIRSF PIRSF007519 1 813 4.6E-215 T 10-11-2016 IPR012300 Peptidase M6, InhA A4G23_RS09500 d098f90093e15a07fe16624186709965 813 Pfam PF05547 Immune inhibitor A peptidase M6 106 806 1.8E-222 T 10-11-2016 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 A4G23_RS09500 d098f90093e15a07fe16624186709965 813 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 173 487 6.8E-82 T 10-11-2016 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 A4G23_RS17955 5cd5d382d036036e686c40ab6a7d6029 322 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS17955 5cd5d382d036036e686c40ab6a7d6029 322 SUPERFAMILY SSF52540 5 225 6.07E-61 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS17955 5cd5d382d036036e686c40ab6a7d6029 322 Pfam PF13732 Domain of unknown function (DUF4162) 217 308 3.0E-7 T 10-11-2016 IPR025302 Domain of unknown function DUF4162 A4G23_RS17955 5cd5d382d036036e686c40ab6a7d6029 322 SMART SM00382 29 218 5.8E-9 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS17955 5cd5d382d036036e686c40ab6a7d6029 322 Gene3D G3DSA:3.40.50.300 3 232 2.5E-71 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS17955 5cd5d382d036036e686c40ab6a7d6029 322 Pfam PF00005 ABC transporter 20 163 1.4E-27 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS17955 5cd5d382d036036e686c40ab6a7d6029 322 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 12 310 9.4E-109 T 10-11-2016 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 A4G23_RS10170 cd8fa9af364aeab0f9726650620acbd6 385 Gene3D G3DSA:3.40.50.2000 19 147 8.8E-6 T 10-11-2016 A4G23_RS10170 cd8fa9af364aeab0f9726650620acbd6 385 Pfam PF13439 Glycosyltransferase Family 4 21 175 8.8E-16 T 10-11-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A4G23_RS10170 cd8fa9af364aeab0f9726650620acbd6 385 Gene3D G3DSA:3.40.50.2000 195 341 1.3E-20 T 10-11-2016 A4G23_RS10170 cd8fa9af364aeab0f9726650620acbd6 385 Pfam PF00534 Glycosyl transferases group 1 193 340 2.3E-23 T 10-11-2016 IPR001296 Glycosyl transferase, family 1 A4G23_RS10170 cd8fa9af364aeab0f9726650620acbd6 385 SUPERFAMILY SSF53756 11 374 2.76E-63 T 10-11-2016 A4G23_RS16810 6a2970bf69b75a45310e33bb576bb46e 320 PIRSF PIRSF016838 2 320 1.3E-24 T 10-11-2016 IPR028349 Protein PafC A4G23_RS16810 6a2970bf69b75a45310e33bb576bb46e 320 Pfam PF08279 HTH domain 7 61 2.6E-15 T 10-11-2016 IPR013196 Helix-turn-helix, type 11 A4G23_RS16810 6a2970bf69b75a45310e33bb576bb46e 320 ProSitePatterns PS00894 DeoR-type HTH domain signature. 7 41 - T 10-11-2016 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 A4G23_RS16810 6a2970bf69b75a45310e33bb576bb46e 320 Pfam PF13280 WYL domain 141 312 1.4E-32 T 10-11-2016 IPR026881 WYL domain A4G23_RS16810 6a2970bf69b75a45310e33bb576bb46e 320 SUPERFAMILY SSF46785 5 62 5.17E-11 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS16810 6a2970bf69b75a45310e33bb576bb46e 320 Gene3D G3DSA:1.10.10.10 1 64 9.4E-20 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS01540 72cbf08382b5fad699b486a9c590f532 320 Pfam PF00583 Acetyltransferase (GNAT) family 231 297 4.2E-8 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS01540 72cbf08382b5fad699b486a9c590f532 320 SUPERFAMILY SSF55729 115 299 8.78E-20 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS01540 72cbf08382b5fad699b486a9c590f532 320 SUPERFAMILY SSF55729 6 147 1.6E-10 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS01540 72cbf08382b5fad699b486a9c590f532 320 Gene3D G3DSA:3.40.630.30 173 299 5.8E-18 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS01540 72cbf08382b5fad699b486a9c590f532 320 Gene3D G3DSA:3.40.630.30 5 151 2.3E-10 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS14430 d91cb6fbf3d38135a6541558b5fcc51e 150 SMART SM00422 18 87 8.3E-26 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS14430 d91cb6fbf3d38135a6541558b5fcc51e 150 SUPERFAMILY SSF46955 18 105 5.49E-19 T 10-11-2016 IPR009061 Putative DNA-binding domain A4G23_RS14430 d91cb6fbf3d38135a6541558b5fcc51e 150 Gene3D G3DSA:1.10.1660.10 19 117 1.6E-21 T 10-11-2016 A4G23_RS14430 d91cb6fbf3d38135a6541558b5fcc51e 150 ProSitePatterns PS00552 MerR-type HTH domain signature. 21 43 - T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS14430 d91cb6fbf3d38135a6541558b5fcc51e 150 Pfam PF13411 MerR HTH family regulatory protein 18 85 1.1E-16 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS25645 c1ba2ef8b9ce3ed99f4e8f689600dbfa 289 Pfam PF13560 Helix-turn-helix domain 27 81 6.3E-13 T 10-11-2016 A4G23_RS25645 c1ba2ef8b9ce3ed99f4e8f689600dbfa 289 SUPERFAMILY SSF47413 26 81 3.1E-11 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS25645 c1ba2ef8b9ce3ed99f4e8f689600dbfa 289 Gene3D G3DSA:1.10.260.40 26 81 1.6E-12 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS25645 c1ba2ef8b9ce3ed99f4e8f689600dbfa 289 SMART SM00530 31 86 5.9E-10 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS02285 41a24b3896057b5a528543dc2bbd406a 485 TIGRFAM TIGR02095 glgA: glycogen/starch synthase, ADP-glucose type 1 480 3.0E-106 T 10-11-2016 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 A4G23_RS02285 41a24b3896057b5a528543dc2bbd406a 485 SUPERFAMILY SSF53756 1 481 1.05E-71 T 10-11-2016 A4G23_RS02285 41a24b3896057b5a528543dc2bbd406a 485 Gene3D G3DSA:3.40.50.2000 256 461 2.2E-53 T 10-11-2016 A4G23_RS02285 41a24b3896057b5a528543dc2bbd406a 485 Pfam PF00534 Glycosyl transferases group 1 293 442 7.1E-14 T 10-11-2016 IPR001296 Glycosyl transferase, family 1 A4G23_RS02285 41a24b3896057b5a528543dc2bbd406a 485 Pfam PF08323 Starch synthase catalytic domain 4 242 5.7E-36 T 10-11-2016 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 A4G23_RS02285 41a24b3896057b5a528543dc2bbd406a 485 Hamap MF_00484 Glycogen synthase [glgA]. 1 481 30.736 T 10-11-2016 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 A4G23_RS11350 cdcc39ff302a7305cd1becaabc1458b4 259 SUPERFAMILY SSF51197 28 113 3.02E-8 T 10-11-2016 A4G23_RS11350 cdcc39ff302a7305cd1becaabc1458b4 259 SUPERFAMILY SSF51197 140 245 3.02E-8 T 10-11-2016 A4G23_RS11350 cdcc39ff302a7305cd1becaabc1458b4 259 Gene3D G3DSA:2.60.120.620 163 245 1.9E-7 T 10-11-2016 A4G23_RS16720 d9f5061010a88e214ddc08cdadbc6246 73 SMART SM00316 5 73 6.0E-5 T 10-11-2016 IPR022967 RNA-binding domain, S1 A4G23_RS16720 d9f5061010a88e214ddc08cdadbc6246 73 SUPERFAMILY SSF50249 4 72 9.06E-28 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS16720 d9f5061010a88e214ddc08cdadbc6246 73 Pfam PF01176 Translation initiation factor 1A / IF-1 8 71 3.4E-29 T 10-11-2016 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 A4G23_RS16720 d9f5061010a88e214ddc08cdadbc6246 73 Gene3D G3DSA:2.40.50.140 2 73 1.5E-39 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS16720 d9f5061010a88e214ddc08cdadbc6246 73 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 4 72 6.4E-38 T 10-11-2016 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 A4G23_RS16720 d9f5061010a88e214ddc08cdadbc6246 73 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 2 73 26.761 T 10-11-2016 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 A4G23_RS12315 a64ceac4f5fe2fb0f60d84cb67e78804 683 SUPERFAMILY SSF53098 363 469 2.75E-15 T 10-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 A4G23_RS12315 a64ceac4f5fe2fb0f60d84cb67e78804 683 SUPERFAMILY SSF53098 261 328 2.75E-15 T 10-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 A4G23_RS12315 a64ceac4f5fe2fb0f60d84cb67e78804 683 Gene3D G3DSA:3.30.420.10 263 321 1.1E-28 T 10-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 A4G23_RS12315 a64ceac4f5fe2fb0f60d84cb67e78804 683 Gene3D G3DSA:3.30.420.10 359 472 1.1E-28 T 10-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 A4G23_RS12315 a64ceac4f5fe2fb0f60d84cb67e78804 683 Pfam PF00665 Integrase core domain 348 417 2.2E-10 T 10-11-2016 IPR001584 Integrase, catalytic core GO:0015074 A4G23_RS12315 a64ceac4f5fe2fb0f60d84cb67e78804 683 Pfam PF09299 Mu transposase, C-terminal 506 571 7.0E-8 T 10-11-2016 IPR015378 Transposase-like, Mu, C-terminal A4G23_RS00365 a04df829e847b239a4fb35a7c60b437a 104 SUPERFAMILY SSF55729 5 81 5.22E-20 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS00365 a04df829e847b239a4fb35a7c60b437a 104 Pfam PF14542 GCN5-related N-acetyl-transferase 9 84 4.8E-20 T 10-11-2016 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase A4G23_RS00365 a04df829e847b239a4fb35a7c60b437a 104 Gene3D G3DSA:3.40.630.30 6 87 9.0E-19 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS03590 d448de265b7d3ea386ba8efed10e9644 370 Gene3D G3DSA:3.40.350.10 5 136 1.6E-12 T 10-11-2016 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A4G23_RS03590 d448de265b7d3ea386ba8efed10e9644 370 SUPERFAMILY SSF53092 5 139 1.22E-14 T 10-11-2016 IPR028980 Creatinase/Aminopeptidase P, N-terminal A4G23_RS03590 d448de265b7d3ea386ba8efed10e9644 370 Pfam PF01321 Creatinase/Prolidase N-terminal domain 8 140 1.5E-12 T 10-11-2016 IPR000587 Creatinase, N-terminal GO:0016787 A4G23_RS03590 d448de265b7d3ea386ba8efed10e9644 370 Gene3D G3DSA:3.90.230.10 140 367 3.7E-57 T 10-11-2016 IPR000994 Peptidase M24, structural domain A4G23_RS03590 d448de265b7d3ea386ba8efed10e9644 370 Pfam PF00557 Metallopeptidase family M24 148 350 2.1E-45 T 10-11-2016 IPR000994 Peptidase M24, structural domain A4G23_RS03590 d448de265b7d3ea386ba8efed10e9644 370 SUPERFAMILY SSF55920 139 368 5.36E-57 T 10-11-2016 IPR000994 Peptidase M24, structural domain A4G23_RS05850 f7aff0415c59943c311a95780a75e209 598 SUPERFAMILY SSF53955 88 256 1.83E-34 T 10-11-2016 IPR023346 Lysozyme-like domain A4G23_RS05850 f7aff0415c59943c311a95780a75e209 598 Gene3D G3DSA:2.60.40.920 383 471 7.4E-6 T 10-11-2016 IPR003344 Big-1 (bacterial Ig-like domain 1) domain A4G23_RS05850 f7aff0415c59943c311a95780a75e209 598 Gene3D G3DSA:1.10.530.10 113 134 7.2E-11 T 10-11-2016 A4G23_RS05850 f7aff0415c59943c311a95780a75e209 598 Gene3D G3DSA:1.10.530.10 171 256 7.2E-11 T 10-11-2016 A4G23_RS05850 f7aff0415c59943c311a95780a75e209 598 PRINTS PR01217 Proline rich extensin signature 275 287 2.8E-9 T 10-11-2016 A4G23_RS05850 f7aff0415c59943c311a95780a75e209 598 PRINTS PR01217 Proline rich extensin signature 324 345 2.8E-9 T 10-11-2016 A4G23_RS05850 f7aff0415c59943c311a95780a75e209 598 PRINTS PR01217 Proline rich extensin signature 308 320 2.8E-9 T 10-11-2016 A4G23_RS05850 f7aff0415c59943c311a95780a75e209 598 PRINTS PR01217 Proline rich extensin signature 349 365 2.8E-9 T 10-11-2016 A4G23_RS05850 f7aff0415c59943c311a95780a75e209 598 SUPERFAMILY SSF49373 382 470 3.4E-5 T 10-11-2016 IPR008964 Invasin/intimin cell-adhesion fragments A4G23_RS05850 f7aff0415c59943c311a95780a75e209 598 Pfam PF13406 Transglycosylase SLT domain 177 219 3.7E-6 T 10-11-2016 IPR031304 Transglycosylase SLT domain 2 A4G23_RS23565 bc9ad592cc11bee371cee1aaaa57bc0f 446 SUPERFAMILY SSF53383 18 443 3.21E-111 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS23565 bc9ad592cc11bee371cee1aaaa57bc0f 446 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 252 289 - T 10-11-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4G23_RS23565 bc9ad592cc11bee371cee1aaaa57bc0f 446 Pfam PF00202 Aminotransferase class-III 28 442 6.6E-91 T 10-11-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4G23_RS23565 bc9ad592cc11bee371cee1aaaa57bc0f 446 Gene3D G3DSA:3.40.640.10 65 332 8.2E-68 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS23565 bc9ad592cc11bee371cee1aaaa57bc0f 446 TIGRFAM TIGR00709 dat: 2,4-diaminobutyrate 4-transaminase 10 443 2.5E-145 T 10-11-2016 IPR004637 2,4-diaminobutyrate 4-transaminase GO:0008483|GO:0009058 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761 A4G23_RS23565 bc9ad592cc11bee371cee1aaaa57bc0f 446 Gene3D G3DSA:3.90.1150.10 335 443 3.7E-38 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS23565 bc9ad592cc11bee371cee1aaaa57bc0f 446 Gene3D G3DSA:3.90.1150.10 12 64 3.7E-38 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS23955 2bbc82f1e0b9f55d9ed8ea9867d3b5c7 389 ProSitePatterns PS01125 ROK family signature. 165 192 - T 10-11-2016 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A4G23_RS23955 2bbc82f1e0b9f55d9ed8ea9867d3b5c7 389 Gene3D G3DSA:3.30.420.40 171 319 2.1E-51 T 10-11-2016 A4G23_RS23955 2bbc82f1e0b9f55d9ed8ea9867d3b5c7 389 TIGRFAM TIGR00744 ROK_glcA_fam: ROK family protein (putative glucokinase) 37 346 5.6E-91 T 10-11-2016 IPR004654 Glucokinase ROK GO:0004340|GO:0005737|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 A4G23_RS23955 2bbc82f1e0b9f55d9ed8ea9867d3b5c7 389 Pfam PF00480 ROK family 36 346 2.2E-78 T 10-11-2016 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A4G23_RS23955 2bbc82f1e0b9f55d9ed8ea9867d3b5c7 389 SUPERFAMILY SSF53067 36 347 1.4E-67 T 10-11-2016 A4G23_RS23955 2bbc82f1e0b9f55d9ed8ea9867d3b5c7 389 Gene3D G3DSA:3.30.420.40 36 170 3.8E-44 T 10-11-2016 A4G23_RS13190 7a66af79e432b573a050db9743ec964e 212 Pfam PF03551 Transcriptional regulator PadR-like family 7 77 1.3E-14 T 10-11-2016 IPR005149 Transcription regulator PadR, N-terminal A4G23_RS13190 7a66af79e432b573a050db9743ec964e 212 Pfam PF10400 Virulence activator alpha C-term 91 176 6.5E-12 T 10-11-2016 IPR018309 Transcription regulator PadR, C-terminal A4G23_RS13190 7a66af79e432b573a050db9743ec964e 212 Gene3D G3DSA:1.10.10.10 1 84 7.4E-23 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS13190 7a66af79e432b573a050db9743ec964e 212 SUPERFAMILY SSF46785 3 176 2.16E-31 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS20820 3939d0fda2bb974b7737a4aa05d2c4ec 296 SUPERFAMILY SSF103481 216 295 5.75E-16 T 10-11-2016 A4G23_RS20820 3939d0fda2bb974b7737a4aa05d2c4ec 296 SUPERFAMILY SSF103481 44 147 7.45E-11 T 10-11-2016 A4G23_RS20820 3939d0fda2bb974b7737a4aa05d2c4ec 296 Pfam PF00892 EamA-like transporter family 16 143 2.9E-16 T 10-11-2016 IPR000620 EamA domain GO:0016020|GO:0016021 A4G23_RS20820 3939d0fda2bb974b7737a4aa05d2c4ec 296 Pfam PF00892 EamA-like transporter family 155 292 1.9E-21 T 10-11-2016 IPR000620 EamA domain GO:0016020|GO:0016021 A4G23_RS03785 e102964fdc328486bd58e5eeabb25a80 186 Gene3D G3DSA:3.30.428.10 46 184 1.3E-37 T 10-11-2016 IPR011146 HIT-like domain GO:0003824 A4G23_RS03785 e102964fdc328486bd58e5eeabb25a80 186 Pfam PF01230 HIT domain 60 151 1.3E-12 T 10-11-2016 IPR001310 Histidine triad (HIT) protein A4G23_RS03785 e102964fdc328486bd58e5eeabb25a80 186 SUPERFAMILY SSF54197 22 179 5.1E-41 T 10-11-2016 IPR011146 HIT-like domain GO:0003824 A4G23_RS22775 cac8ad6e81169882c0ab8840da99f3d9 388 Pfam PF01594 Domain of unknown function DUF20 25 345 2.1E-56 T 10-11-2016 IPR002549 Transmembrane protein TqsA-like A4G23_RS10020 a7ff6a53b78a6b87f59e1a6bd7ced042 399 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 102 257 1.1E-46 T 10-11-2016 IPR004474 Cell envelope-related transcriptional attenuator domain A4G23_RS10020 a7ff6a53b78a6b87f59e1a6bd7ced042 399 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 102 257 3.3E-46 T 10-11-2016 IPR004474 Cell envelope-related transcriptional attenuator domain A4G23_RS24420 2b3f64ff37c260611b71210b961440eb 191 Gene3D G3DSA:1.20.120.450 6 73 2.1E-5 T 10-11-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase A4G23_RS24420 2b3f64ff37c260611b71210b961440eb 191 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 10 189 3.2E-54 T 10-11-2016 IPR017520 Conserved hypothetical protein CHP03086 A4G23_RS24420 2b3f64ff37c260611b71210b961440eb 191 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 10 186 2.3E-29 T 10-11-2016 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type A4G23_RS24420 2b3f64ff37c260611b71210b961440eb 191 SUPERFAMILY SSF109854 4 138 2.93E-21 T 10-11-2016 A4G23_RS24420 2b3f64ff37c260611b71210b961440eb 191 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 12 133 1.1E-15 T 10-11-2016 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 A4G23_RS21760 87d8d495531b05833f93b9ebf50d656b 134 Pfam PF00571 CBS domain 31 70 5.9E-4 T 10-11-2016 IPR000644 CBS domain A4G23_RS21760 87d8d495531b05833f93b9ebf50d656b 134 Gene3D G3DSA:3.10.580.10 17 131 1.4E-11 T 10-11-2016 A4G23_RS21760 87d8d495531b05833f93b9ebf50d656b 134 SUPERFAMILY SSF54631 19 132 2.71E-14 T 10-11-2016 A4G23_RS24260 ff1e085967b51e409566f1784775449b 294 Pfam PF01066 CDP-alcohol phosphatidyltransferase 40 119 1.1E-11 T 10-11-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A4G23_RS24260 ff1e085967b51e409566f1784775449b 294 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 98 119 - T 10-11-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A4G23_RS24260 ff1e085967b51e409566f1784775449b 294 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 45 217 6.0E-34 T 10-11-2016 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 A4G23_RS05295 6ab6f2898175f39af98fffb8ba2134b5 501 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 262 432 4.0E-41 T 10-11-2016 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 A4G23_RS05295 6ab6f2898175f39af98fffb8ba2134b5 501 SUPERFAMILY SSF52540 5 241 2.79E-51 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05295 6ab6f2898175f39af98fffb8ba2134b5 501 SUPERFAMILY SSF52317 274 408 4.59E-35 T 10-11-2016 IPR029062 Class I glutamine amidotransferase-like A4G23_RS05295 6ab6f2898175f39af98fffb8ba2134b5 501 SUPERFAMILY SSF52317 193 239 4.59E-35 T 10-11-2016 IPR029062 Class I glutamine amidotransferase-like A4G23_RS05295 6ab6f2898175f39af98fffb8ba2134b5 501 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 5 479 8.0E-134 T 10-11-2016 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 A4G23_RS05295 6ab6f2898175f39af98fffb8ba2134b5 501 Gene3D G3DSA:3.40.50.880 262 444 5.7E-39 T 10-11-2016 IPR029062 Class I glutamine amidotransferase-like A4G23_RS05295 6ab6f2898175f39af98fffb8ba2134b5 501 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 6 214 4.2E-24 T 10-11-2016 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A4G23_RS05295 6ab6f2898175f39af98fffb8ba2134b5 501 Gene3D G3DSA:3.40.50.300 5 237 1.7E-42 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05295 6ab6f2898175f39af98fffb8ba2134b5 501 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 488 173.048 T 10-11-2016 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 A4G23_RS07260 99a0a70705d847089ad7eefc8ee6e828 275 Gene3D G3DSA:1.10.260.40 13 68 4.4E-14 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS07260 99a0a70705d847089ad7eefc8ee6e828 275 SMART SM00530 19 73 1.2E-11 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS07260 99a0a70705d847089ad7eefc8ee6e828 275 SUPERFAMILY SSF47413 15 68 2.59E-12 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS07260 99a0a70705d847089ad7eefc8ee6e828 275 Pfam PF13560 Helix-turn-helix domain 15 71 4.9E-13 T 10-11-2016 A4G23_RS23090 70216535f10b32a85d091009b13b782f 252 SMART SM00479 7 188 2.8E-19 T 10-11-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III A4G23_RS23090 70216535f10b32a85d091009b13b782f 252 SUPERFAMILY SSF53098 3 202 3.0E-45 T 10-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 A4G23_RS23090 70216535f10b32a85d091009b13b782f 252 Gene3D G3DSA:3.30.420.10 2 186 3.8E-40 T 10-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 A4G23_RS23090 70216535f10b32a85d091009b13b782f 252 Pfam PF00929 Exonuclease 9 176 6.4E-15 T 10-11-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III A4G23_RS21930 f6b855adede2422b0161bb086c996c81 805 Gene3D G3DSA:1.20.1640.10 131 342 3.6E-27 T 10-11-2016 A4G23_RS21930 f6b855adede2422b0161bb086c996c81 805 Gene3D G3DSA:1.20.1640.10 512 718 3.4E-29 T 10-11-2016 A4G23_RS21930 f6b855adede2422b0161bb086c996c81 805 SUPERFAMILY SSF82866 118 338 4.05E-23 T 10-11-2016 A4G23_RS21930 f6b855adede2422b0161bb086c996c81 805 SUPERFAMILY SSF82866 464 712 9.02E-24 T 10-11-2016 A4G23_RS21930 f6b855adede2422b0161bb086c996c81 805 Pfam PF03176 MMPL family 411 746 5.5E-33 T 10-11-2016 IPR004869 Membrane transport protein, MMPL domain GO:0016020 A4G23_RS21930 f6b855adede2422b0161bb086c996c81 805 Pfam PF03176 MMPL family 67 376 5.3E-32 T 10-11-2016 IPR004869 Membrane transport protein, MMPL domain GO:0016020 A4G23_RS19920 37156487bf04af18c7c4a69646b1d452 212 SUPERFAMILY SSF55729 72 103 1.37E-7 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS19920 37156487bf04af18c7c4a69646b1d452 212 SUPERFAMILY SSF55729 147 203 1.37E-7 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS19920 37156487bf04af18c7c4a69646b1d452 212 Pfam PF00583 Acetyltransferase (GNAT) family 142 201 8.9E-5 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS19920 37156487bf04af18c7c4a69646b1d452 212 Gene3D G3DSA:3.40.630.30 67 95 2.7E-6 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS19920 37156487bf04af18c7c4a69646b1d452 212 Gene3D G3DSA:3.40.630.30 142 203 2.7E-6 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS05735 0ac1b08a77976ebbc5722d000e051683 677 Gene3D G3DSA:2.60.60.30 68 162 1.9E-19 T 10-11-2016 A4G23_RS05735 0ac1b08a77976ebbc5722d000e051683 677 Pfam PF02342 TerD domain 66 162 9.7E-20 T 10-11-2016 IPR003325 TerD domain GO:0006950 A4G23_RS06195 8f06d1deb9e39491fba33eb622ced4af 418 SUPERFAMILY SSF109635 287 382 1.44E-9 T 10-11-2016 A4G23_RS06195 8f06d1deb9e39491fba33eb622ced4af 418 SUPERFAMILY SSF57716 383 417 5.7E-7 T 10-11-2016 A4G23_RS06195 8f06d1deb9e39491fba33eb622ced4af 418 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 381 416 6.5E-11 T 10-11-2016 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 A4G23_RS05320 1b478bfc02e89c581d4de802bf343257 367 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 213 226 - T 10-11-2016 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 A4G23_RS05320 1b478bfc02e89c581d4de802bf343257 367 Gene3D G3DSA:3.90.1150.10 256 358 5.7E-17 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS05320 1b478bfc02e89c581d4de802bf343257 367 SUPERFAMILY SSF53383 32 358 1.06E-59 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS05320 1b478bfc02e89c581d4de802bf343257 367 Gene3D G3DSA:3.40.640.10 47 255 3.4E-51 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS05320 1b478bfc02e89c581d4de802bf343257 367 Pfam PF00155 Aminotransferase class I and II 37 354 1.0E-29 T 10-11-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4G23_RS15985 8f36e4c9c834256adfff9e4700b07271 286 Hamap MF_00995 Chorismate dehydratase [mqnA]. 10 272 31.224 T 10-11-2016 IPR030868 Chorismate dehydratase GO:0009234|GO:0016829 KEGG: 00130+4.2.1.151|MetaCyc: PWY-7371|MetaCyc: PWY-7374 A4G23_RS15985 8f36e4c9c834256adfff9e4700b07271 286 Pfam PF02621 Menaquinone biosynthesis 10 266 9.1E-70 T 10-11-2016 IPR003773 Menaquinone biosynthesis enzyme A4G23_RS15985 8f36e4c9c834256adfff9e4700b07271 286 Gene3D G3DSA:3.40.190.10 185 282 6.6E-68 T 10-11-2016 A4G23_RS15985 8f36e4c9c834256adfff9e4700b07271 286 Gene3D G3DSA:3.40.190.10 5 82 6.6E-68 T 10-11-2016 A4G23_RS15985 8f36e4c9c834256adfff9e4700b07271 286 Gene3D G3DSA:3.40.190.10 83 184 6.3E-36 T 10-11-2016 A4G23_RS15985 8f36e4c9c834256adfff9e4700b07271 286 SUPERFAMILY SSF53850 9 265 2.17E-76 T 10-11-2016 A4G23_RS03805 b2d5479d725273fd98dc37b77ef7cf19 242 Gene3D G3DSA:3.30.420.10 3 187 6.6E-40 T 10-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 A4G23_RS03805 b2d5479d725273fd98dc37b77ef7cf19 242 SUPERFAMILY SSF53098 4 200 7.59E-43 T 10-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 A4G23_RS03805 b2d5479d725273fd98dc37b77ef7cf19 242 Pfam PF00929 Exonuclease 11 179 3.3E-16 T 10-11-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III A4G23_RS03805 b2d5479d725273fd98dc37b77ef7cf19 242 SMART SM00479 8 189 3.3E-24 T 10-11-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III A4G23_RS21325 1bacedc6bd9375d5b2c1d470601dc86d 236 SUPERFAMILY SSF53098 17 219 1.35E-56 T 10-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 A4G23_RS21325 1bacedc6bd9375d5b2c1d470601dc86d 236 Hamap MF_00052_B Ribonuclease HII [rnhB]. 22 205 33.986 T 10-11-2016 IPR022898 Ribonuclease HII GO:0004523 A4G23_RS21325 1bacedc6bd9375d5b2c1d470601dc86d 236 Pfam PF01351 Ribonuclease HII 24 203 2.6E-33 T 10-11-2016 IPR024567 Ribonuclease HII/HIII domain A4G23_RS21325 1bacedc6bd9375d5b2c1d470601dc86d 236 Gene3D G3DSA:3.30.420.10 22 162 1.0E-40 T 10-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 A4G23_RS12670 6beb8f3dbfbd9429f4a324fb82fab984 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 6.0E-13 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS12670 6beb8f3dbfbd9429f4a324fb82fab984 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 6.0E-13 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS12670 6beb8f3dbfbd9429f4a324fb82fab984 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 6.0E-13 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS12670 6beb8f3dbfbd9429f4a324fb82fab984 219 Pfam PF00072 Response regulator receiver domain 4 113 1.6E-26 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS12670 6beb8f3dbfbd9429f4a324fb82fab984 219 Pfam PF00196 Bacterial regulatory proteins, luxR family 157 212 3.9E-16 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS12670 6beb8f3dbfbd9429f4a324fb82fab984 219 Gene3D G3DSA:1.10.10.10 123 218 1.4E-30 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS12670 6beb8f3dbfbd9429f4a324fb82fab984 219 SUPERFAMILY SSF52172 1 133 1.38E-34 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS12670 6beb8f3dbfbd9429f4a324fb82fab984 219 Gene3D G3DSA:3.40.50.2300 1 122 7.4E-37 T 10-11-2016 A4G23_RS12670 6beb8f3dbfbd9429f4a324fb82fab984 219 ProSitePatterns PS00622 LuxR-type HTH domain signature. 172 199 - T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS12670 6beb8f3dbfbd9429f4a324fb82fab984 219 SMART SM00448 2 115 3.1E-33 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS12670 6beb8f3dbfbd9429f4a324fb82fab984 219 SMART SM00421 155 212 2.5E-23 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS12670 6beb8f3dbfbd9429f4a324fb82fab984 219 SUPERFAMILY SSF46894 147 218 1.26E-20 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS12060 63d90d8be52171b87e47d6afb1c81f9c 322 SUPERFAMILY SSF49785 207 313 1.22E-9 T 10-11-2016 IPR008979 Galactose-binding domain-like A4G23_RS12060 63d90d8be52171b87e47d6afb1c81f9c 322 Gene3D G3DSA:2.60.120.260 199 311 1.8E-11 T 10-11-2016 IPR008979 Galactose-binding domain-like A4G23_RS19535 c4b4b628728c90788b77fb4915071284 447 Pfam PF00953 Glycosyl transferase family 4 83 243 5.7E-35 T 10-11-2016 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 A4G23_RS17350 e7df18b4a95da7f22c40512de4e26759 519 Gene3D G3DSA:3.10.105.10 291 489 5.6E-36 T 10-11-2016 A4G23_RS17350 e7df18b4a95da7f22c40512de4e26759 519 SUPERFAMILY SSF53850 32 518 3.26E-86 T 10-11-2016 A4G23_RS17350 e7df18b4a95da7f22c40512de4e26759 519 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 78 439 1.2E-56 T 10-11-2016 IPR000914 Solute-binding protein family 5 domain A4G23_RS17350 e7df18b4a95da7f22c40512de4e26759 519 Gene3D G3DSA:3.40.190.10 162 290 2.6E-23 T 10-11-2016 A4G23_RS17350 e7df18b4a95da7f22c40512de4e26759 519 Gene3D G3DSA:3.90.76.10 68 161 2.6E-16 T 10-11-2016 A4G23_RS17350 e7df18b4a95da7f22c40512de4e26759 519 PIRSF PIRSF002741 25 518 5.4E-56 T 10-11-2016 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A4G23_RS20500 2da14a20fd066e9191e3870baf59e845 147 SUPERFAMILY SSF54565 2 94 5.36E-34 T 10-11-2016 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS20500 2da14a20fd066e9191e3870baf59e845 147 ProSitePatterns PS00732 Ribosomal protein S16 signature. 3 12 - T 10-11-2016 IPR020592 Ribosomal protein S16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS20500 2da14a20fd066e9191e3870baf59e845 147 Pfam PF00886 Ribosomal protein S16 9 67 8.8E-24 T 10-11-2016 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS20500 2da14a20fd066e9191e3870baf59e845 147 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 77 23.659 T 10-11-2016 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS20500 2da14a20fd066e9191e3870baf59e845 147 Gene3D G3DSA:3.30.1320.10 2 83 4.4E-33 T 10-11-2016 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS20500 2da14a20fd066e9191e3870baf59e845 147 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 79 5.9E-32 T 10-11-2016 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS25250 bf1b9eed903ab61dbf4b962fcb52c45e 173 SUPERFAMILY SSF140663 30 159 1.96E-24 T 10-11-2016 IPR023203 TTHA0068-like domain A4G23_RS25250 bf1b9eed903ab61dbf4b962fcb52c45e 173 Pfam PF03745 Domain of unknown function (DUF309) 49 111 6.7E-18 T 10-11-2016 IPR005500 Protein of unknown function DUF309 A4G23_RS25250 bf1b9eed903ab61dbf4b962fcb52c45e 173 Gene3D G3DSA:1.10.3450.10 19 160 4.4E-21 T 10-11-2016 IPR023203 TTHA0068-like domain A4G23_RS17460 b91e9d1b015a5ca54f3691ac2bd9c33b 128 SUPERFAMILY SSF54909 1 116 5.9E-15 T 10-11-2016 IPR011008 Dimeric alpha-beta barrel A4G23_RS17460 b91e9d1b015a5ca54f3691ac2bd9c33b 128 Pfam PF05336 Domain of unknown function (DUF718) 4 115 1.5E-17 T 10-11-2016 IPR008000 Rhamnose/fucose mutarotase GO:0005737|GO:0016857 A4G23_RS04720 9816bc70e94788120cb427845e193a8c 124 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 78 1.1E-15 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS04720 9816bc70e94788120cb427845e193a8c 124 SUPERFAMILY SSF46785 9 94 1.44E-20 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS04720 9816bc70e94788120cb427845e193a8c 124 SMART SM00345 19 78 3.0E-12 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS04720 9816bc70e94788120cb427845e193a8c 124 Gene3D G3DSA:1.10.10.10 5 79 1.8E-24 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS02985 9e74898b62dc5d8726db5a2c78cfdf9d 367 SUPERFAMILY SSF103481 243 336 2.09E-9 T 10-11-2016 A4G23_RS02985 9e74898b62dc5d8726db5a2c78cfdf9d 367 Pfam PF00892 EamA-like transporter family 60 187 1.4E-17 T 10-11-2016 IPR000620 EamA domain GO:0016020|GO:0016021 A4G23_RS02985 9e74898b62dc5d8726db5a2c78cfdf9d 367 Pfam PF00892 EamA-like transporter family 199 334 3.9E-15 T 10-11-2016 IPR000620 EamA domain GO:0016020|GO:0016021 A4G23_RS02985 9e74898b62dc5d8726db5a2c78cfdf9d 367 SUPERFAMILY SSF103481 88 188 3.92E-10 T 10-11-2016 A4G23_RS17405 e62b072c662321511c572343ebd501de 222 SUPERFAMILY SSF50475 11 192 1.12E-50 T 10-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 A4G23_RS17405 e62b072c662321511c572343ebd501de 222 Gene3D G3DSA:2.30.110.10 7 192 7.3E-64 T 10-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 A4G23_RS17405 e62b072c662321511c572343ebd501de 222 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 28 169 9.9E-43 T 10-11-2016 IPR024747 Pyridoxamine 5'-phosphate oxidase-related A4G23_RS05275 02d9f50549ca34f07d6a0faa5c52f824 233 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 29 200 4.5E-48 T 10-11-2016 IPR001303 Class II aldolase/adducin N-terminal A4G23_RS05275 02d9f50549ca34f07d6a0faa5c52f824 233 SMART SM01007 28 201 3.4E-60 T 10-11-2016 IPR001303 Class II aldolase/adducin N-terminal A4G23_RS05275 02d9f50549ca34f07d6a0faa5c52f824 233 Gene3D G3DSA:3.40.225.10 24 230 3.2E-66 T 10-11-2016 IPR001303 Class II aldolase/adducin N-terminal A4G23_RS05275 02d9f50549ca34f07d6a0faa5c52f824 233 SUPERFAMILY SSF53639 24 230 4.91E-60 T 10-11-2016 IPR001303 Class II aldolase/adducin N-terminal A4G23_RS19625 b8a348491cb326342e47e3f77d6498db 982 SUPERFAMILY SSF52540 100 305 7.67E-9 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS19625 b8a348491cb326342e47e3f77d6498db 982 Gene3D G3DSA:3.40.50.300 113 234 6.9E-6 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS23275 025da1d9442c4770f526f2937e163880 1136 Pfam PF02687 FtsX-like permease family 1003 1119 9.6E-10 T 10-11-2016 IPR003838 ABC transporter permease protein domain GO:0016020 A4G23_RS23275 025da1d9442c4770f526f2937e163880 1136 Pfam PF02687 FtsX-like permease family 316 427 1.4E-8 T 10-11-2016 IPR003838 ABC transporter permease protein domain GO:0016020 A4G23_RS04110 8a0f0cee693636bb0ec9fad7cb8df450 285 Gene3D G3DSA:3.40.1280.10 120 274 1.6E-47 T 10-11-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A4G23_RS04110 8a0f0cee693636bb0ec9fad7cb8df450 285 Gene3D G3DSA:3.30.1330.30 6 108 3.2E-28 T 10-11-2016 IPR029064 50S ribosomal protein L30e-like A4G23_RS04110 8a0f0cee693636bb0ec9fad7cb8df450 285 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 34 106 1.1E-9 T 10-11-2016 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 A4G23_RS04110 8a0f0cee693636bb0ec9fad7cb8df450 285 SUPERFAMILY SSF55315 6 108 1.77E-19 T 10-11-2016 IPR029064 50S ribosomal protein L30e-like A4G23_RS04110 8a0f0cee693636bb0ec9fad7cb8df450 285 SUPERFAMILY SSF75217 117 277 1.24E-40 T 10-11-2016 IPR029028 Alpha/beta knot methyltransferases A4G23_RS04110 8a0f0cee693636bb0ec9fad7cb8df450 285 Pfam PF00588 SpoU rRNA Methylase family 123 267 1.0E-35 T 10-11-2016 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 A4G23_RS04110 8a0f0cee693636bb0ec9fad7cb8df450 285 SMART SM00967 33 112 5.5E-10 T 10-11-2016 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 A4G23_RS12705 d8ba35a3e66de021a45b4fffaaa9384c 425 Gene3D G3DSA:1.20.1250.20 210 385 6.3E-13 T 10-11-2016 A4G23_RS12705 d8ba35a3e66de021a45b4fffaaa9384c 425 Pfam PF07690 Major Facilitator Superfamily 9 241 8.9E-18 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS12705 d8ba35a3e66de021a45b4fffaaa9384c 425 Gene3D G3DSA:1.20.1250.20 7 178 4.1E-20 T 10-11-2016 A4G23_RS12705 d8ba35a3e66de021a45b4fffaaa9384c 425 SUPERFAMILY SSF103473 6 387 8.11E-43 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS11580 d0b2c003aed50e14e83f8b90acc6edfe 946 SUPERFAMILY SSF55103 226 488 1.96E-55 T 10-11-2016 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 A4G23_RS11580 d0b2c003aed50e14e83f8b90acc6edfe 946 Pfam PF01565 FAD binding domain 39 176 1.4E-40 T 10-11-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 A4G23_RS11580 d0b2c003aed50e14e83f8b90acc6edfe 946 SUPERFAMILY SSF46548 473 611 1.99E-7 T 10-11-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 A4G23_RS11580 d0b2c003aed50e14e83f8b90acc6edfe 946 Gene3D G3DSA:3.30.465.10 94 251 2.8E-32 T 10-11-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 A4G23_RS11580 d0b2c003aed50e14e83f8b90acc6edfe 946 SUPERFAMILY SSF56176 6 251 4.07E-54 T 10-11-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 A4G23_RS11580 d0b2c003aed50e14e83f8b90acc6edfe 946 Gene3D G3DSA:3.30.43.10 5 89 1.9E-19 T 10-11-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 A4G23_RS11580 d0b2c003aed50e14e83f8b90acc6edfe 946 Gene3D G3DSA:1.10.1060.10 525 619 3.4E-11 T 10-11-2016 A4G23_RS11580 d0b2c003aed50e14e83f8b90acc6edfe 946 Pfam PF02913 FAD linked oxidases, C-terminal domain 251 486 1.9E-48 T 10-11-2016 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 A4G23_RS11580 d0b2c003aed50e14e83f8b90acc6edfe 946 Pfam PF13183 4Fe-4S dicluster domain 525 606 1.5E-9 T 10-11-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4G23_RS26560 14fd57f59b3d3a1786fc497a98219fda 204 Pfam PF04978 Protein of unknown function (DUF664) 8 159 2.7E-38 T 10-11-2016 IPR007061 Protein of unknown function DUF664 A4G23_RS26560 14fd57f59b3d3a1786fc497a98219fda 204 Gene3D G3DSA:1.20.120.450 6 161 1.4E-28 T 10-11-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase A4G23_RS26560 14fd57f59b3d3a1786fc497a98219fda 204 SUPERFAMILY SSF109854 2 158 4.76E-33 T 10-11-2016 A4G23_RS23550 018e5ae68264226e7096babf7270e986 596 Pfam PF06276 Ferric iron reductase FhuF-like transporter 414 575 1.4E-29 T 10-11-2016 IPR022770 Ferric iron reductase FhuF domain A4G23_RS23550 018e5ae68264226e7096babf7270e986 596 Pfam PF04183 IucA / IucC family 131 381 4.9E-61 T 10-11-2016 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0015343|GO:0019290 A4G23_RS17335 5ab30d3a4b4d3d8c20765e4432e9e7d1 420 Gene3D G3DSA:3.40.710.10 76 332 3.4E-68 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS17335 5ab30d3a4b4d3d8c20765e4432e9e7d1 420 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 77 311 2.3E-35 T 10-11-2016 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 A4G23_RS17335 5ab30d3a4b4d3d8c20765e4432e9e7d1 420 SUPERFAMILY SSF56601 11 32 4.33E-46 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS17335 5ab30d3a4b4d3d8c20765e4432e9e7d1 420 SUPERFAMILY SSF56601 79 331 4.33E-46 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS10165 f51fddf6b1de4700305b769560feb160 179 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 124 157 4.0E-6 T 10-11-2016 IPR001451 Hexapeptide repeat A4G23_RS10165 f51fddf6b1de4700305b769560feb160 179 Gene3D G3DSA:2.160.10.10 37 165 3.8E-30 T 10-11-2016 A4G23_RS10165 f51fddf6b1de4700305b769560feb160 179 SUPERFAMILY SSF51161 24 165 9.56E-31 T 10-11-2016 IPR011004 Trimeric LpxA-like A4G23_RS17060 66c0c10fcfe2bbc76052c93cb6ddcd3d 146 Gene3D G3DSA:1.20.59.10 64 123 1.8E-9 T 10-11-2016 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A4G23_RS17060 66c0c10fcfe2bbc76052c93cb6ddcd3d 146 Pfam PF01817 Chorismate mutase type II 75 126 2.0E-7 T 10-11-2016 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A4G23_RS17060 66c0c10fcfe2bbc76052c93cb6ddcd3d 146 SUPERFAMILY SSF48600 72 129 6.41E-10 T 10-11-2016 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A4G23_RS17060 66c0c10fcfe2bbc76052c93cb6ddcd3d 146 SMART SM00830 75 143 2.1E-4 T 10-11-2016 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A4G23_RS19505 f6dc2c4e8abe61b6725aa70dc6518fa5 73 SUPERFAMILY SSF143800 1 66 3.92E-24 T 10-11-2016 A4G23_RS19505 f6dc2c4e8abe61b6725aa70dc6518fa5 73 ProSitePatterns PS01143 Ribosomal protein L31 signature. 36 57 - T 10-11-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS19505 f6dc2c4e8abe61b6725aa70dc6518fa5 73 Pfam PF01197 Ribosomal protein L31 2 66 5.6E-30 T 10-11-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS19505 f6dc2c4e8abe61b6725aa70dc6518fa5 73 PRINTS PR01249 Ribosomal protein L31 signature 47 65 1.6E-20 T 10-11-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS19505 f6dc2c4e8abe61b6725aa70dc6518fa5 73 PRINTS PR01249 Ribosomal protein L31 signature 2 19 1.6E-20 T 10-11-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS19505 f6dc2c4e8abe61b6725aa70dc6518fa5 73 PRINTS PR01249 Ribosomal protein L31 signature 32 47 1.6E-20 T 10-11-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS19505 f6dc2c4e8abe61b6725aa70dc6518fa5 73 TIGRFAM TIGR00105 L31: ribosomal protein bL31 2 67 5.9E-33 T 10-11-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS19505 f6dc2c4e8abe61b6725aa70dc6518fa5 73 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 69 28.455 T 10-11-2016 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS23850 3c0f9b766184615d90208a3ea2aac9e9 199 Gene3D G3DSA:3.30.420.10 7 194 1.9E-18 T 10-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 A4G23_RS23850 3c0f9b766184615d90208a3ea2aac9e9 199 SUPERFAMILY SSF53098 7 195 1.58E-23 T 10-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 A4G23_RS23850 3c0f9b766184615d90208a3ea2aac9e9 199 Pfam PF00929 Exonuclease 18 190 7.9E-5 T 10-11-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III A4G23_RS24670 b0181ce3e66760dc2d522b3037f51906 603 SUPERFAMILY SSF51905 189 392 8.42E-33 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS24670 b0181ce3e66760dc2d522b3037f51906 603 SUPERFAMILY SSF51905 56 155 8.42E-33 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS24670 b0181ce3e66760dc2d522b3037f51906 603 SUPERFAMILY SSF51905 524 560 8.42E-33 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS24670 b0181ce3e66760dc2d522b3037f51906 603 Pfam PF01593 Flavin containing amine oxidoreductase 63 560 1.8E-20 T 10-11-2016 IPR002937 Amine oxidase GO:0016491|GO:0055114 A4G23_RS24670 b0181ce3e66760dc2d522b3037f51906 603 Gene3D G3DSA:3.50.50.60 283 357 2.6E-26 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS24670 b0181ce3e66760dc2d522b3037f51906 603 Gene3D G3DSA:3.50.50.60 56 102 2.6E-26 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS24670 b0181ce3e66760dc2d522b3037f51906 603 Gene3D G3DSA:3.50.50.60 496 563 2.6E-26 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS27160 6809ed9828ca015ee199e6e97ced38c1 178 Gene3D G3DSA:1.10.357.10 51 176 2.6E-21 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS27160 6809ed9828ca015ee199e6e97ced38c1 178 SUPERFAMILY SSF46689 1 51 3.69E-16 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS27160 6809ed9828ca015ee199e6e97ced38c1 178 SUPERFAMILY SSF48498 84 175 6.23E-13 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS27160 6809ed9828ca015ee199e6e97ced38c1 178 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 1 14 2.8E-12 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS27160 6809ed9828ca015ee199e6e97ced38c1 178 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 45 2.8E-12 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS27160 6809ed9828ca015ee199e6e97ced38c1 178 Pfam PF00440 Bacterial regulatory proteins, tetR family 1 46 2.6E-20 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS27160 6809ed9828ca015ee199e6e97ced38c1 178 ProSitePatterns PS01081 TetR-type HTH domain signature. 13 43 - T 10-11-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A4G23_RS27160 6809ed9828ca015ee199e6e97ced38c1 178 Gene3D G3DSA:1.10.10.60 1 47 1.8E-20 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS10740 c20b60cb603a4b9a321336cb7a048c9a 321 Gene3D G3DSA:3.40.50.1820 17 290 3.8E-52 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS10740 c20b60cb603a4b9a321336cb7a048c9a 321 Pfam PF12697 Alpha/beta hydrolase family 37 285 1.0E-20 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS10740 c20b60cb603a4b9a321336cb7a048c9a 321 SUPERFAMILY SSF53474 18 289 1.65E-49 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS10740 c20b60cb603a4b9a321336cb7a048c9a 321 PRINTS PR00111 Alpha/beta hydrolase fold signature 108 121 2.4E-5 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS10740 c20b60cb603a4b9a321336cb7a048c9a 321 PRINTS PR00111 Alpha/beta hydrolase fold signature 236 250 2.4E-5 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS10740 c20b60cb603a4b9a321336cb7a048c9a 321 PRINTS PR00111 Alpha/beta hydrolase fold signature 60 75 2.4E-5 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS18160 46f753325c52da85899751d515de0ae9 319 Pfam PF01478 Type IV leader peptidase family 173 279 1.2E-16 T 10-11-2016 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 A4G23_RS18160 46f753325c52da85899751d515de0ae9 319 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 249 260 1.5E-6 T 10-11-2016 IPR014032 Peptidase A24A, prepilin type IV, bacterial A4G23_RS18160 46f753325c52da85899751d515de0ae9 319 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 238 248 1.5E-6 T 10-11-2016 IPR014032 Peptidase A24A, prepilin type IV, bacterial A4G23_RS18160 46f753325c52da85899751d515de0ae9 319 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 181 198 1.5E-6 T 10-11-2016 IPR014032 Peptidase A24A, prepilin type IV, bacterial A4G23_RS09640 95e5ec50d111d022a270c1a82e382f7e 297 Gene3D G3DSA:3.30.390.50 181 260 1.1E-4 T 10-11-2016 A4G23_RS09640 95e5ec50d111d022a270c1a82e382f7e 297 SUPERFAMILY SSF55447 180 230 1.73E-5 T 10-11-2016 IPR005107 CO dehydrogenase flavoprotein, C-terminal A4G23_RS09640 95e5ec50d111d022a270c1a82e382f7e 297 SUPERFAMILY SSF56176 10 174 4.58E-42 T 10-11-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 A4G23_RS09640 95e5ec50d111d022a270c1a82e382f7e 297 Gene3D G3DSA:3.30.465.10 63 174 9.3E-30 T 10-11-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 A4G23_RS09640 95e5ec50d111d022a270c1a82e382f7e 297 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 12 174 9.4E-42 T 10-11-2016 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 A4G23_RS09640 95e5ec50d111d022a270c1a82e382f7e 297 Gene3D G3DSA:3.30.43.10 14 62 1.7E-7 T 10-11-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 A4G23_RS13475 d4f207367f24ee85cc466285fd1df953 45 ProSitePatterns PS00784 Ribosomal protein L34 signature. 3 22 - T 10-11-2016 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS13475 d4f207367f24ee85cc466285fd1df953 45 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 3 40 1.0E-13 T 10-11-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS13475 d4f207367f24ee85cc466285fd1df953 45 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 3 45 4.7E-20 T 10-11-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS13475 d4f207367f24ee85cc466285fd1df953 45 Pfam PF00468 Ribosomal protein L34 3 45 3.2E-20 T 10-11-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS13475 d4f207367f24ee85cc466285fd1df953 45 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 2 45 15.698 T 10-11-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS16550 d851f95d8e7a6718cc26bfc1ec7f2686 184 SUPERFAMILY SSF55874 40 130 2.8E-6 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS16550 d851f95d8e7a6718cc26bfc1ec7f2686 184 Pfam PF13581 Histidine kinase-like ATPase domain 26 124 6.3E-10 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS07605 710c9041541eed6fb081724f0f8a21c5 238 Gene3D G3DSA:1.20.910.10 2 235 2.7E-42 T 10-11-2016 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 A4G23_RS07605 710c9041541eed6fb081724f0f8a21c5 238 SUPERFAMILY SSF48613 7 230 1.39E-32 T 10-11-2016 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 A4G23_RS07605 710c9041541eed6fb081724f0f8a21c5 238 SMART SM01236 76 185 6.5E-21 T 10-11-2016 A4G23_RS07605 710c9041541eed6fb081724f0f8a21c5 238 Pfam PF14518 Iron-containing redox enzyme 43 223 3.5E-30 T 10-11-2016 IPR028201 PqqC-like protein A4G23_RS04695 4fc66f340999df5dc0ea48ab0272b1ac 260 PIRSF PIRSF006648 2 259 9.9E-63 T 10-11-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 A4G23_RS04695 4fc66f340999df5dc0ea48ab0272b1ac 260 Pfam PF01061 ABC-2 type transporter 10 215 1.0E-28 T 10-11-2016 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A4G23_RS12270 8725fa07ff265a856ffe28cca45adcd1 354 SUPERFAMILY SSF54001 238 347 1.67E-34 T 10-11-2016 A4G23_RS12270 8725fa07ff265a856ffe28cca45adcd1 354 Gene3D G3DSA:3.90.1720.10 236 341 1.8E-37 T 10-11-2016 IPR000064 Endopeptidase, NLPC/P60 domain A4G23_RS12270 8725fa07ff265a856ffe28cca45adcd1 354 Pfam PF00877 NlpC/P60 family 253 335 2.1E-20 T 10-11-2016 IPR000064 Endopeptidase, NLPC/P60 domain A4G23_RS20465 66e96d2cf9e90981b902348982c9f3da 489 Gene3D G3DSA:1.25.40.10 251 443 1.5E-8 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS20465 66e96d2cf9e90981b902348982c9f3da 489 SUPERFAMILY SSF48452 410 445 1.06E-9 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS20465 66e96d2cf9e90981b902348982c9f3da 489 SUPERFAMILY SSF48452 232 350 1.06E-9 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS25700 1d810af73094c816ad01abf268def518 488 Gene3D G3DSA:3.40.50.720 328 466 1.9E-43 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS25700 1d810af73094c816ad01abf268def518 488 Gene3D G3DSA:3.40.50.720 132 235 1.9E-43 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS25700 1d810af73094c816ad01abf268def518 488 SUPERFAMILY SSF51735 331 442 7.87E-27 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS25700 1d810af73094c816ad01abf268def518 488 SUPERFAMILY SSF51735 145 242 7.87E-27 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS25700 1d810af73094c816ad01abf268def518 488 Pfam PF00106 short chain dehydrogenase 151 244 8.0E-10 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS07485 4e3959d2e4fc03b94445b7e656465511 227 Gene3D G3DSA:2.60.120.10 18 223 8.7E-42 T 10-11-2016 IPR014710 RmlC-like jelly roll fold A4G23_RS07485 4e3959d2e4fc03b94445b7e656465511 227 Pfam PF02678 Pirin 18 119 3.7E-28 T 10-11-2016 IPR003829 Pirin, N-terminal domain A4G23_RS07485 4e3959d2e4fc03b94445b7e656465511 227 SUPERFAMILY SSF51182 17 223 8.92E-45 T 10-11-2016 IPR011051 RmlC-like cupin domain A4G23_RS07900 2b76435cf27b43cafb52866ee07ab21d 349 SUPERFAMILY SSF51556 21 335 7.09E-83 T 10-11-2016 IPR032466 Metal-dependent hydrolase A4G23_RS07900 2b76435cf27b43cafb52866ee07ab21d 349 Pfam PF00962 Adenosine/AMP deaminase 22 336 2.3E-71 T 10-11-2016 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 A4G23_RS07900 2b76435cf27b43cafb52866ee07ab21d 349 Gene3D G3DSA:3.20.20.140 21 338 5.4E-99 T 10-11-2016 A4G23_RS07900 2b76435cf27b43cafb52866ee07ab21d 349 Hamap MF_01962 Adenine deaminase. 18 330 82.334 T 10-11-2016 IPR028892 Adenine deaminase type 2 GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 A4G23_RS07900 2b76435cf27b43cafb52866ee07ab21d 349 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 22 340 2.9E-113 T 10-11-2016 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 A4G23_RS20380 80b94d9c29b02933744cc30daa7ab330 280 Pfam PF08543 Phosphomethylpyrimidine kinase 27 269 4.8E-90 T 10-11-2016 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-964975 A4G23_RS20380 80b94d9c29b02933744cc30daa7ab330 280 SUPERFAMILY SSF53613 17 272 2.81E-77 T 10-11-2016 IPR029056 Ribokinase-like A4G23_RS20380 80b94d9c29b02933744cc30daa7ab330 280 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 20 270 7.4E-94 T 10-11-2016 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A4G23_RS20380 80b94d9c29b02933744cc30daa7ab330 280 Gene3D G3DSA:3.40.1190.20 18 270 9.2E-100 T 10-11-2016 IPR029056 Ribokinase-like A4G23_RS08415 7e44e764129111da6e1f7de5feffdb37 180 Pfam PF07336 Putative stress-induced transcription regulator 13 129 1.3E-12 T 10-11-2016 IPR010852 Putative stress-induced transcription regulator A4G23_RS08415 7e44e764129111da6e1f7de5feffdb37 180 Pfam PF11706 CGNR zinc finger 134 176 2.8E-19 T 10-11-2016 IPR021005 Zinc finger, CGNR A4G23_RS08415 7e44e764129111da6e1f7de5feffdb37 180 SUPERFAMILY SSF160904 5 176 9.02E-41 T 10-11-2016 A4G23_RS08415 7e44e764129111da6e1f7de5feffdb37 180 Gene3D G3DSA:1.10.3300.10 5 178 1.1E-44 T 10-11-2016 IPR023286 ABATE domain A4G23_RS14255 eb671208a816f59cc9a87f91633cb552 235 SUPERFAMILY SSF56037 58 226 8.11E-28 T 10-11-2016 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 Reactome: R-HSA-379716 A4G23_RS14255 eb671208a816f59cc9a87f91633cb552 235 Pfam PF03483 B3/4 domain 65 194 1.3E-24 T 10-11-2016 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 A4G23_RS14255 eb671208a816f59cc9a87f91633cb552 235 Gene3D G3DSA:3.50.40.10 65 192 3.1E-16 T 10-11-2016 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 Reactome: R-HSA-379716 A4G23_RS14255 eb671208a816f59cc9a87f91633cb552 235 SMART SM00873 63 219 5.8E-14 T 10-11-2016 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 A4G23_RS18210 903c9d206eb9144fe4fda68ff891e5af 316 SUPERFAMILY SSF56219 101 314 8.51E-24 T 10-11-2016 IPR005135 Endonuclease/exonuclease/phosphatase A4G23_RS18210 903c9d206eb9144fe4fda68ff891e5af 316 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 106 307 9.2E-19 T 10-11-2016 IPR005135 Endonuclease/exonuclease/phosphatase A4G23_RS18210 903c9d206eb9144fe4fda68ff891e5af 316 Gene3D G3DSA:3.60.10.10 99 255 4.1E-7 T 10-11-2016 IPR005135 Endonuclease/exonuclease/phosphatase A4G23_RS15190 14739e8e0f97c8adeadc59f5d9e758f0 378 SMART SM00833 236 352 5.0E-39 T 10-11-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal A4G23_RS15190 14739e8e0f97c8adeadc59f5d9e758f0 378 Gene3D G3DSA:3.40.50.300 66 206 4.4E-9 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS15190 14739e8e0f97c8adeadc59f5d9e758f0 378 Gene3D G3DSA:3.30.1220.10 229 352 1.4E-7 T 10-11-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal A4G23_RS15190 14739e8e0f97c8adeadc59f5d9e758f0 378 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 65 172 3.3E-5 T 10-11-2016 IPR003495 CobW/HypB/UreG, nucleotide-binding domain A4G23_RS15190 14739e8e0f97c8adeadc59f5d9e758f0 378 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 237 352 4.3E-20 T 10-11-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal A4G23_RS15190 14739e8e0f97c8adeadc59f5d9e758f0 378 SUPERFAMILY SSF90002 237 352 6.15E-11 T 10-11-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal A4G23_RS15040 af60817cdd75cae956548957e4752815 288 PRINTS PR00092 Tyrosinase copper-binding domain signature 199 210 2.0E-18 T 10-11-2016 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 A4G23_RS15040 af60817cdd75cae956548957e4752815 288 PRINTS PR00092 Tyrosinase copper-binding domain signature 218 236 2.0E-18 T 10-11-2016 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 A4G23_RS15040 af60817cdd75cae956548957e4752815 288 PRINTS PR00092 Tyrosinase copper-binding domain signature 84 89 2.0E-18 T 10-11-2016 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 A4G23_RS15040 af60817cdd75cae956548957e4752815 288 PRINTS PR00092 Tyrosinase copper-binding domain signature 55 72 2.0E-18 T 10-11-2016 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 A4G23_RS15040 af60817cdd75cae956548957e4752815 288 Pfam PF00264 Common central domain of tyrosinase 31 238 6.4E-41 T 10-11-2016 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 A4G23_RS15040 af60817cdd75cae956548957e4752815 288 ProSitePatterns PS00497 Tyrosinase CuA-binding region signature. 55 72 - T 10-11-2016 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 A4G23_RS15040 af60817cdd75cae956548957e4752815 288 SUPERFAMILY SSF48056 3 287 4.41E-59 T 10-11-2016 IPR008922 Uncharacterised domain, di-copper centre A4G23_RS15040 af60817cdd75cae956548957e4752815 288 ProSitePatterns PS00498 Tyrosinase and hemocyanins CuB-binding region signature. 219 230 - T 10-11-2016 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 A4G23_RS15040 af60817cdd75cae956548957e4752815 288 Gene3D G3DSA:1.10.1280.10 3 283 1.4E-59 T 10-11-2016 IPR008922 Uncharacterised domain, di-copper centre A4G23_RS22500 81fb0b2939b52511594d7a6ba6fb42cd 258 Gene3D G3DSA:3.75.10.10 1 254 1.6E-66 T 10-11-2016 A4G23_RS22500 81fb0b2939b52511594d7a6ba6fb42cd 258 SUPERFAMILY SSF55909 1 256 3.53E-58 T 10-11-2016 A4G23_RS22500 81fb0b2939b52511594d7a6ba6fb42cd 258 Pfam PF02274 Amidinotransferase 1 255 8.0E-23 T 10-11-2016 A4G23_RS26510 154accbcbce39a84e681da8e66d6c5b9 670 TIGRFAM TIGR02242 tail_TIGR02242: phage tail protein domain 382 489 1.2E-19 T 10-11-2016 IPR011748 Uncharacterised protein family, phage tail-like A4G23_RS26510 154accbcbce39a84e681da8e66d6c5b9 670 Pfam PF09684 Phage tail protein (Tail_P2_I) 405 497 1.1E-14 T 10-11-2016 IPR006521 Tail protein I A4G23_RS26510 154accbcbce39a84e681da8e66d6c5b9 670 Gene3D G3DSA:2.120.10.30 104 227 2.6E-4 T 10-11-2016 IPR011042 Six-bladed beta-propeller, TolB-like A4G23_RS26510 154accbcbce39a84e681da8e66d6c5b9 670 SUPERFAMILY SSF63825 93 215 5.75E-6 T 10-11-2016 A4G23_RS26020 a0ae70afa5d61b6eba48d2a4a3c85d2e 277 ProSitePatterns PS00953 Glycosyl hydrolases family 25 active sites signature. 76 109 - T 10-11-2016 IPR008270 Glycoside hydrolase, family 25, active site GO:0003796|GO:0009253|GO:0016998 A4G23_RS26020 a0ae70afa5d61b6eba48d2a4a3c85d2e 277 SMART SM00641 72 181 6.5E-47 T 10-11-2016 IPR018077 Glycoside hydrolase, family 25 subgroup A4G23_RS26020 a0ae70afa5d61b6eba48d2a4a3c85d2e 277 Gene3D G3DSA:3.20.20.80 72 276 2.1E-69 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS26020 a0ae70afa5d61b6eba48d2a4a3c85d2e 277 SUPERFAMILY SSF51445 73 276 3.02E-62 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS26020 a0ae70afa5d61b6eba48d2a4a3c85d2e 277 Pfam PF01183 Glycosyl hydrolases family 25 75 259 8.0E-54 T 10-11-2016 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 A4G23_RS25670 f532c1a884619b8191d00a84dd766ba7 312 Pfam PF12146 Serine aminopeptidase, S33 105 201 5.1E-7 T 10-11-2016 IPR022742 Serine aminopeptidase, S33 A4G23_RS25670 f532c1a884619b8191d00a84dd766ba7 312 SUPERFAMILY SSF53474 55 301 4.57E-47 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS25670 f532c1a884619b8191d00a84dd766ba7 312 Gene3D G3DSA:3.40.50.1820 55 302 1.2E-68 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS25480 b0f49b058933af1a90e60d4c941a6046 347 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 9 308 5.0E-116 T 10-11-2016 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 A4G23_RS25480 b0f49b058933af1a90e60d4c941a6046 347 Pfam PF03741 Integral membrane protein TerC family 74 276 7.4E-53 T 10-11-2016 IPR005496 Integral membrane protein TerC GO:0016021 A4G23_RS17490 3842600c582a9126653d3fa78de29e50 530 Gene3D G3DSA:2.170.220.10 110 253 5.3E-25 T 10-11-2016 A4G23_RS17490 3842600c582a9126653d3fa78de29e50 530 Gene3D G3DSA:3.40.50.620 254 360 1.4E-33 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS17490 3842600c582a9126653d3fa78de29e50 530 Gene3D G3DSA:3.40.50.620 6 109 1.4E-33 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS17490 3842600c582a9126653d3fa78de29e50 530 PRINTS PR01041 Methionyl-tRNA synthetase signature 251 262 1.2E-6 T 10-11-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A4G23_RS17490 3842600c582a9126653d3fa78de29e50 530 PRINTS PR01041 Methionyl-tRNA synthetase signature 7 20 1.2E-6 T 10-11-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A4G23_RS17490 3842600c582a9126653d3fa78de29e50 530 PRINTS PR01041 Methionyl-tRNA synthetase signature 89 100 1.2E-6 T 10-11-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A4G23_RS17490 3842600c582a9126653d3fa78de29e50 530 PRINTS PR01041 Methionyl-tRNA synthetase signature 279 294 1.2E-6 T 10-11-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A4G23_RS17490 3842600c582a9126653d3fa78de29e50 530 PRINTS PR01041 Methionyl-tRNA synthetase signature 40 54 1.2E-6 T 10-11-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A4G23_RS17490 3842600c582a9126653d3fa78de29e50 530 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 12 23 - T 10-11-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4G23_RS17490 3842600c582a9126653d3fa78de29e50 530 Gene3D G3DSA:1.10.730.10 382 523 4.1E-5 T 10-11-2016 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4G23_RS17490 3842600c582a9126653d3fa78de29e50 530 SUPERFAMILY SSF52374 175 371 4.22E-68 T 10-11-2016 A4G23_RS17490 3842600c582a9126653d3fa78de29e50 530 SUPERFAMILY SSF52374 6 141 4.22E-68 T 10-11-2016 A4G23_RS17490 3842600c582a9126653d3fa78de29e50 530 Pfam PF09334 tRNA synthetases class I (M) 6 375 1.3E-67 T 10-11-2016 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4G23_RS01555 80d8bc04c873a07166c4006d845d7519 132 Pfam PF04471 Restriction endonuclease 6 118 9.0E-24 T 10-11-2016 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 A4G23_RS01555 80d8bc04c873a07166c4006d845d7519 132 SUPERFAMILY SSF52980 10 120 3.7E-20 T 10-11-2016 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A4G23_RS01555 80d8bc04c873a07166c4006d845d7519 132 Gene3D G3DSA:3.40.1350.10 7 120 1.7E-25 T 10-11-2016 IPR011856 tRNA endonuclease-like domain GO:0003676|GO:0004518 Reactome: R-HSA-6784531 A4G23_RS00415 e2795c0e2e2eddeb333293576ce3159d 250 SUPERFAMILY SSF46689 199 246 1.61E-9 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS00415 e2795c0e2e2eddeb333293576ce3159d 250 Gene3D G3DSA:1.10.10.60 201 243 3.3E-11 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS00415 e2795c0e2e2eddeb333293576ce3159d 250 SMART SM00342 163 245 5.9E-28 T 10-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4G23_RS00415 e2795c0e2e2eddeb333293576ce3159d 250 SUPERFAMILY SSF51182 14 170 3.93E-19 T 10-11-2016 IPR011051 RmlC-like cupin domain A4G23_RS00415 e2795c0e2e2eddeb333293576ce3159d 250 Gene3D G3DSA:2.60.120.10 15 82 7.2E-11 T 10-11-2016 IPR014710 RmlC-like jelly roll fold A4G23_RS00415 e2795c0e2e2eddeb333293576ce3159d 250 Pfam PF07883 Cupin domain 14 78 4.0E-7 T 10-11-2016 IPR013096 Cupin 2, conserved barrel A4G23_RS00415 e2795c0e2e2eddeb333293576ce3159d 250 Pfam PF12833 Helix-turn-helix domain 171 247 9.7E-24 T 10-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4G23_RS00415 e2795c0e2e2eddeb333293576ce3159d 250 Gene3D G3DSA:1.10.10.60 142 200 3.7E-14 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS09535 e716cef3b86abaf5f7edc43df16f31b1 381 TIGRFAM TIGR01263 4HPPD: 4-hydroxyphenylpyruvate dioxygenase 22 381 2.0E-137 T 10-11-2016 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 A4G23_RS09535 e716cef3b86abaf5f7edc43df16f31b1 381 SUPERFAMILY SSF54593 14 368 5.09E-93 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS09535 e716cef3b86abaf5f7edc43df16f31b1 381 Gene3D G3DSA:3.10.180.10 15 187 6.3E-44 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS09535 e716cef3b86abaf5f7edc43df16f31b1 381 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 185 335 1.5E-16 T 10-11-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4G23_RS09535 e716cef3b86abaf5f7edc43df16f31b1 381 PIRSF PIRSF009283 9 381 1.4E-136 T 10-11-2016 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 A4G23_RS09535 e716cef3b86abaf5f7edc43df16f31b1 381 Gene3D G3DSA:3.10.180.10 188 381 4.7E-80 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS09535 e716cef3b86abaf5f7edc43df16f31b1 381 Pfam PF14696 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal 15 157 1.6E-7 T 10-11-2016 A4G23_RS23185 e5d2f0db9a869716552c15636f4feebd 224 Gene3D G3DSA:3.40.50.620 6 196 1.1E-55 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS23185 e5d2f0db9a869716552c15636f4feebd 224 PIRSF PIRSF000857 1 224 3.1E-90 T 10-11-2016 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 A4G23_RS23185 e5d2f0db9a869716552c15636f4feebd 224 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 37 199 2.7E-41 T 10-11-2016 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 A4G23_RS23185 e5d2f0db9a869716552c15636f4feebd 224 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 18 223 6.6E-58 T 10-11-2016 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 A4G23_RS23185 e5d2f0db9a869716552c15636f4feebd 224 SUPERFAMILY SSF52402 8 185 2.3E-47 T 10-11-2016 A4G23_RS25660 73b4ac0b246d82c01c470cda54f0dfc3 379 SUPERFAMILY SSF53335 13 191 4.09E-24 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS25660 73b4ac0b246d82c01c470cda54f0dfc3 379 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 56 191 1.2E-22 T 10-11-2016 A4G23_RS25660 73b4ac0b246d82c01c470cda54f0dfc3 379 Gene3D G3DSA:3.40.50.150 15 227 5.7E-42 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS04390 60aac32e6edc96844f9dedeb63ee5037 319 PIRSF PIRSF028754 2 288 6.3E-123 T 10-11-2016 IPR008492 Protein of unknown function DUF774 A4G23_RS04390 60aac32e6edc96844f9dedeb63ee5037 319 SUPERFAMILY SSF159659 3 260 1.1E-88 T 10-11-2016 A4G23_RS04390 60aac32e6edc96844f9dedeb63ee5037 319 Pfam PF09754 PAC2 family 19 236 3.4E-53 T 10-11-2016 IPR019151 Proteasome assembly chaperone 2 A4G23_RS10365 27116f17cc01dc7e6032a5da75e91752 89 SUPERFAMILY SSF143011 3 85 2.62E-21 T 10-11-2016 A4G23_RS10365 27116f17cc01dc7e6032a5da75e91752 89 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 6 86 8.8E-11 T 10-11-2016 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family A4G23_RS06795 0de295948d5f5986d774e741d181f36d 343 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 5 82 2.1E-15 T 10-11-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4G23_RS06795 0de295948d5f5986d774e741d181f36d 343 Pfam PF00120 Glutamine synthetase, catalytic domain 94 236 7.1E-14 T 10-11-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4G23_RS06795 0de295948d5f5986d774e741d181f36d 343 SUPERFAMILY SSF55931 90 338 1.37E-65 T 10-11-2016 A4G23_RS06795 0de295948d5f5986d774e741d181f36d 343 SUPERFAMILY SSF54368 6 88 3.01E-13 T 10-11-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4G23_RS06795 0de295948d5f5986d774e741d181f36d 343 ProSitePatterns PS00180 Glutamine synthetase signature 1. 41 58 - T 10-11-2016 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 A4G23_RS06795 0de295948d5f5986d774e741d181f36d 343 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 219 235 - T 10-11-2016 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 A4G23_RS06795 0de295948d5f5986d774e741d181f36d 343 SMART SM01230 89 333 1.4E-52 T 10-11-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4G23_RS06795 0de295948d5f5986d774e741d181f36d 343 Gene3D G3DSA:3.30.590.10 94 339 4.4E-55 T 10-11-2016 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 A4G23_RS24370 997bbd705c63bd084003b17280ae6941 317 Gene3D G3DSA:3.50.30.60 182 311 3.5E-39 T 10-11-2016 IPR027461 LD-carboxypeptidase A, C-terminal domain A4G23_RS24370 997bbd705c63bd084003b17280ae6941 317 Pfam PF02016 LD-carboxypeptidase 25 301 7.3E-76 T 10-11-2016 IPR003507 Peptidase family S66 A4G23_RS24370 997bbd705c63bd084003b17280ae6941 317 SUPERFAMILY SSF52317 12 177 2.52E-45 T 10-11-2016 IPR029062 Class I glutamine amidotransferase-like A4G23_RS24370 997bbd705c63bd084003b17280ae6941 317 Gene3D G3DSA:3.40.50.10740 12 178 1.8E-51 T 10-11-2016 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal domain A4G23_RS24370 997bbd705c63bd084003b17280ae6941 317 PIRSF PIRSF028757 13 316 1.3E-71 T 10-11-2016 IPR003507 Peptidase family S66 A4G23_RS24370 997bbd705c63bd084003b17280ae6941 317 SUPERFAMILY SSF141986 169 308 1.1E-38 T 10-11-2016 IPR027461 LD-carboxypeptidase A, C-terminal domain A4G23_RS16710 96d3909eff41e500f23de447312af16f 219 TIGRFAM TIGR01351 adk: adenylate kinase 2 213 2.8E-78 T 10-11-2016 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219 A4G23_RS16710 96d3909eff41e500f23de447312af16f 219 Gene3D G3DSA:3.40.50.300 1 212 1.6E-77 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS16710 96d3909eff41e500f23de447312af16f 219 Pfam PF00406 Adenylate kinase 5 191 1.5E-60 T 10-11-2016 A4G23_RS16710 96d3909eff41e500f23de447312af16f 219 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 10-11-2016 A4G23_RS16710 96d3909eff41e500f23de447312af16f 219 PRINTS PR00094 Adenylate kinase signature 81 97 9.0E-36 T 10-11-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A4G23_RS16710 96d3909eff41e500f23de447312af16f 219 PRINTS PR00094 Adenylate kinase signature 32 46 9.0E-36 T 10-11-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A4G23_RS16710 96d3909eff41e500f23de447312af16f 219 PRINTS PR00094 Adenylate kinase signature 161 176 9.0E-36 T 10-11-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A4G23_RS16710 96d3909eff41e500f23de447312af16f 219 PRINTS PR00094 Adenylate kinase signature 4 17 9.0E-36 T 10-11-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A4G23_RS16710 96d3909eff41e500f23de447312af16f 219 PRINTS PR00094 Adenylate kinase signature 178 192 9.0E-36 T 10-11-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A4G23_RS16710 96d3909eff41e500f23de447312af16f 219 Pfam PF05191 Adenylate kinase, active site lid 127 163 1.1E-12 T 10-11-2016 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219 A4G23_RS16710 96d3909eff41e500f23de447312af16f 219 SUPERFAMILY SSF52540 1 214 2.07E-42 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS16710 96d3909eff41e500f23de447312af16f 219 Hamap MF_00235 Adenylate kinase [adk]. 1 214 50.966 T 10-11-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A4G23_RS08915 e7ba83e0882275438895e6c5bcef57ca 844 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 298 304 - T 10-11-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A4G23_RS08915 e7ba83e0882275438895e6c5bcef57ca 844 Gene3D G3DSA:3.40.50.150 195 427 2.5E-34 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS08915 e7ba83e0882275438895e6c5bcef57ca 844 Pfam PF12161 HsdM N-terminal domain 9 157 6.4E-23 T 10-11-2016 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain A4G23_RS08915 e7ba83e0882275438895e6c5bcef57ca 844 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 330 354 6.5E-17 T 10-11-2016 A4G23_RS08915 e7ba83e0882275438895e6c5bcef57ca 844 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 193 209 6.5E-17 T 10-11-2016 A4G23_RS08915 e7ba83e0882275438895e6c5bcef57ca 844 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 295 307 6.5E-17 T 10-11-2016 A4G23_RS08915 e7ba83e0882275438895e6c5bcef57ca 844 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 217 231 6.5E-17 T 10-11-2016 A4G23_RS08915 e7ba83e0882275438895e6c5bcef57ca 844 Pfam PF02384 N-6 DNA Methylase 171 480 1.7E-96 T 10-11-2016 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 A4G23_RS08915 e7ba83e0882275438895e6c5bcef57ca 844 SUPERFAMILY SSF53335 81 536 9.78E-129 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS08915 e7ba83e0882275438895e6c5bcef57ca 844 SUPERFAMILY SSF53335 8 46 9.78E-129 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS00865 036ef87d2759fa03eecf9995d3f0be53 388 Gene3D G3DSA:3.50.50.60 319 365 7.0E-52 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS00865 036ef87d2759fa03eecf9995d3f0be53 388 Gene3D G3DSA:3.50.50.60 134 202 7.0E-52 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS00865 036ef87d2759fa03eecf9995d3f0be53 388 Gene3D G3DSA:3.50.50.60 3 80 7.0E-52 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS00865 036ef87d2759fa03eecf9995d3f0be53 388 Gene3D G3DSA:3.30.9.10 203 317 7.4E-11 T 10-11-2016 A4G23_RS00865 036ef87d2759fa03eecf9995d3f0be53 388 SUPERFAMILY SSF54373 217 319 1.29E-12 T 10-11-2016 A4G23_RS00865 036ef87d2759fa03eecf9995d3f0be53 388 Pfam PF01266 FAD dependent oxidoreductase 4 356 2.5E-60 T 10-11-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A4G23_RS00865 036ef87d2759fa03eecf9995d3f0be53 388 SUPERFAMILY SSF51905 319 372 1.75E-49 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS00865 036ef87d2759fa03eecf9995d3f0be53 388 SUPERFAMILY SSF51905 4 217 1.75E-49 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS19150 22bce66a2e766f35e3e2e5aeaa89906d 329 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 76 314 6.2E-64 T 10-11-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A4G23_RS19150 22bce66a2e766f35e3e2e5aeaa89906d 329 Gene3D G3DSA:3.40.190.10 33 194 9.4E-44 T 10-11-2016 A4G23_RS19150 22bce66a2e766f35e3e2e5aeaa89906d 329 SUPERFAMILY SSF53850 24 314 1.5E-54 T 10-11-2016 A4G23_RS19150 22bce66a2e766f35e3e2e5aeaa89906d 329 SMART SM00062 75 317 2.6E-48 T 10-11-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A4G23_RS19150 22bce66a2e766f35e3e2e5aeaa89906d 329 Gene3D G3DSA:3.40.190.10 195 279 5.9E-19 T 10-11-2016 A4G23_RS17380 2da56547f29cebb812ff54af114efdfb 114 Gene3D G3DSA:1.20.1300.10 1 101 6.1E-27 T 10-11-2016 A4G23_RS17380 2da56547f29cebb812ff54af114efdfb 114 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 1 98 2.8E-26 T 10-11-2016 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4G23_RS17380 2da56547f29cebb812ff54af114efdfb 114 PIRSF PIRSF000178 1 104 1.5E-8 T 10-11-2016 A4G23_RS17380 2da56547f29cebb812ff54af114efdfb 114 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 1 96 2.9E-21 T 10-11-2016 IPR000701 Succinate dehydrogenase/Fumarate reductase, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4G23_RS17380 2da56547f29cebb812ff54af114efdfb 114 SUPERFAMILY SSF81343 1 101 5.89E-24 T 10-11-2016 A4G23_RS03320 82436df4f71a53dbb8bf2703010540cd 275 Pfam PF00106 short chain dehydrogenase 8 196 7.3E-43 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS03320 82436df4f71a53dbb8bf2703010540cd 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.1E-22 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS03320 82436df4f71a53dbb8bf2703010540cd 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 1.1E-22 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS03320 82436df4f71a53dbb8bf2703010540cd 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.1E-22 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS03320 82436df4f71a53dbb8bf2703010540cd 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 1.1E-22 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS03320 82436df4f71a53dbb8bf2703010540cd 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 1.1E-22 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS03320 82436df4f71a53dbb8bf2703010540cd 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 2.4E-9 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS03320 82436df4f71a53dbb8bf2703010540cd 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 2.4E-9 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS03320 82436df4f71a53dbb8bf2703010540cd 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 2.4E-9 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS03320 82436df4f71a53dbb8bf2703010540cd 275 Gene3D G3DSA:3.40.50.720 8 230 5.7E-58 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS03320 82436df4f71a53dbb8bf2703010540cd 275 SUPERFAMILY SSF51735 8 253 1.48E-57 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS23390 82e78676508b42f6804edb89a60c491a 324 Gene3D G3DSA:3.40.50.2020 168 288 3.3E-44 T 10-11-2016 IPR029057 Phosphoribosyltransferase-like A4G23_RS23390 82e78676508b42f6804edb89a60c491a 324 Pfam PF14572 Phosphoribosyl synthetase-associated domain 215 320 3.4E-24 T 10-11-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 A4G23_RS23390 82e78676508b42f6804edb89a60c491a 324 SUPERFAMILY SSF53271 77 313 3.72E-58 T 10-11-2016 IPR029057 Phosphoribosyltransferase-like A4G23_RS23390 82e78676508b42f6804edb89a60c491a 324 SMART SM01400 12 128 5.7E-71 T 10-11-2016 A4G23_RS23390 82e78676508b42f6804edb89a60c491a 324 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 14 321 2.0E-112 T 10-11-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 A4G23_RS23390 82e78676508b42f6804edb89a60c491a 324 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 13 128 1.9E-44 T 10-11-2016 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 A4G23_RS23390 82e78676508b42f6804edb89a60c491a 324 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 12 322 44.796 T 10-11-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 A4G23_RS23390 82e78676508b42f6804edb89a60c491a 324 Gene3D G3DSA:3.40.50.2020 10 167 9.7E-68 T 10-11-2016 IPR029057 Phosphoribosyltransferase-like A4G23_RS13980 6c4ef4d514e8aa8e8b02a9078b7b667a 211 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 3 209 2.0E-76 T 10-11-2016 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 A4G23_RS13980 6c4ef4d514e8aa8e8b02a9078b7b667a 211 Pfam PF14681 Uracil phosphoribosyltransferase 5 209 7.5E-64 T 10-11-2016 IPR029057 Phosphoribosyltransferase-like A4G23_RS13980 6c4ef4d514e8aa8e8b02a9078b7b667a 211 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 2 210 43.799 T 10-11-2016 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 A4G23_RS13980 6c4ef4d514e8aa8e8b02a9078b7b667a 211 Gene3D G3DSA:3.40.50.2020 2 208 3.4E-73 T 10-11-2016 IPR029057 Phosphoribosyltransferase-like A4G23_RS13980 6c4ef4d514e8aa8e8b02a9078b7b667a 211 SUPERFAMILY SSF53271 3 208 9.83E-64 T 10-11-2016 IPR029057 Phosphoribosyltransferase-like A4G23_RS14175 7c2912f9be64b71075377f876fea4764 227 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 3.2E-6 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS14175 7c2912f9be64b71075377f876fea4764 227 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 3.2E-6 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS14175 7c2912f9be64b71075377f876fea4764 227 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 66 2.4E-13 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS14175 7c2912f9be64b71075377f876fea4764 227 Gene3D G3DSA:1.10.357.10 9 221 5.7E-35 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS14175 7c2912f9be64b71075377f876fea4764 227 SUPERFAMILY SSF46689 10 82 5.49E-17 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS14175 7c2912f9be64b71075377f876fea4764 227 SUPERFAMILY SSF48498 87 197 6.35E-5 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS03600 1e3aa6daccea73327949fd4ef2fc2ae9 146 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 146 57.734 T 10-11-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A4G23_RS03600 1e3aa6daccea73327949fd4ef2fc2ae9 146 ProSitePatterns PS01029 Dehydroquinase class II signature. 8 25 - T 10-11-2016 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A4G23_RS03600 1e3aa6daccea73327949fd4ef2fc2ae9 146 Gene3D G3DSA:3.40.50.9100 3 144 1.9E-54 T 10-11-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A4G23_RS03600 1e3aa6daccea73327949fd4ef2fc2ae9 146 Pfam PF01220 Dehydroquinase class II 4 140 3.4E-49 T 10-11-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A4G23_RS03600 1e3aa6daccea73327949fd4ef2fc2ae9 146 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 4 143 2.5E-51 T 10-11-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A4G23_RS03600 1e3aa6daccea73327949fd4ef2fc2ae9 146 SUPERFAMILY SSF52304 4 144 5.1E-52 T 10-11-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A4G23_RS03600 1e3aa6daccea73327949fd4ef2fc2ae9 146 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 5 141 2.0E-38 T 10-11-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A4G23_RS03600 1e3aa6daccea73327949fd4ef2fc2ae9 146 PIRSF PIRSF001399 1 146 2.8E-54 T 10-11-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A4G23_RS24425 f1b41ada587120d7cab5cee0188462b4 185 Pfam PF01965 DJ-1/PfpI family 2 174 4.5E-52 T 10-11-2016 IPR002818 DJ-1/PfpI A4G23_RS24425 f1b41ada587120d7cab5cee0188462b4 185 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 6 172 5.3E-49 T 10-11-2016 IPR006286 Peptidase C56, PfpI A4G23_RS24425 f1b41ada587120d7cab5cee0188462b4 185 SUPERFAMILY SSF52317 2 175 2.15E-43 T 10-11-2016 IPR029062 Class I glutamine amidotransferase-like A4G23_RS24425 f1b41ada587120d7cab5cee0188462b4 185 Gene3D G3DSA:3.40.50.880 2 176 8.4E-54 T 10-11-2016 IPR029062 Class I glutamine amidotransferase-like A4G23_RS12825 6a20d52947c786fa3d0ad0aef8fb2772 289 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 9 176 8.1E-21 T 10-11-2016 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 A4G23_RS06920 5a0ede3de9b0f5c7e9d6e4339e427793 289 Gene3D G3DSA:3.40.50.1820 7 285 1.1E-39 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS06920 5a0ede3de9b0f5c7e9d6e4339e427793 289 SUPERFAMILY SSF53474 6 285 3.12E-42 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS06920 5a0ede3de9b0f5c7e9d6e4339e427793 289 Pfam PF12697 Alpha/beta hydrolase family 29 282 3.7E-19 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS17870 ad6d5fc09fb4093f2248bdf6db039af0 260 Gene3D G3DSA:3.30.70.270 73 224 1.0E-33 T 10-11-2016 A4G23_RS17870 ad6d5fc09fb4093f2248bdf6db039af0 260 SUPERFAMILY SSF55781 4 71 1.44E-9 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS17870 ad6d5fc09fb4093f2248bdf6db039af0 260 Gene3D G3DSA:3.30.450.40 4 65 6.8E-9 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS17870 ad6d5fc09fb4093f2248bdf6db039af0 260 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 69 223 4.4E-25 T 10-11-2016 IPR000160 GGDEF domain A4G23_RS17870 ad6d5fc09fb4093f2248bdf6db039af0 260 SUPERFAMILY SSF55073 76 224 4.47E-29 T 10-11-2016 IPR029787 Nucleotide cyclase A4G23_RS17870 ad6d5fc09fb4093f2248bdf6db039af0 260 Pfam PF01590 GAF domain 5 56 2.5E-4 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS17870 ad6d5fc09fb4093f2248bdf6db039af0 260 SMART SM00267 60 238 2.8E-48 T 10-11-2016 IPR000160 GGDEF domain A4G23_RS17870 ad6d5fc09fb4093f2248bdf6db039af0 260 Pfam PF00990 Diguanylate cyclase, GGDEF domain 71 223 1.4E-26 T 10-11-2016 IPR000160 GGDEF domain A4G23_RS16165 979f56eff10ba2481246a155dc99f950 624 SUPERFAMILY SSF52518 237 505 6.87E-61 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS16165 979f56eff10ba2481246a155dc99f950 624 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 522 592 4.3E-7 T 10-11-2016 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II A4G23_RS16165 979f56eff10ba2481246a155dc99f950 624 Gene3D G3DSA:3.40.920.10 15 214 1.0E-24 T 10-11-2016 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 A4G23_RS16165 979f56eff10ba2481246a155dc99f950 624 Gene3D G3DSA:3.40.50.970 235 428 2.5E-73 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS16165 979f56eff10ba2481246a155dc99f950 624 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 23 211 1.1E-26 T 10-11-2016 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 A4G23_RS16165 979f56eff10ba2481246a155dc99f950 624 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 15 616 1.4E-195 T 10-11-2016 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 A4G23_RS16165 979f56eff10ba2481246a155dc99f950 624 SUPERFAMILY SSF53323 17 240 3.66E-16 T 10-11-2016 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A4G23_RS16165 979f56eff10ba2481246a155dc99f950 624 SUPERFAMILY SSF52922 522 622 5.1E-13 T 10-11-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 A4G23_RS16165 979f56eff10ba2481246a155dc99f950 624 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 264 435 2.0E-51 T 10-11-2016 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 A4G23_RS16165 979f56eff10ba2481246a155dc99f950 624 Gene3D G3DSA:3.40.50.920 522 619 7.1E-10 T 10-11-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 A4G23_RS09575 240574a0f853a3530c328a4209bcd877 166 PIRSF PIRSF021700 1 157 2.0E-65 T 10-11-2016 IPR009725 Predicted 3-demethylubiquinone-9 3-methyltransferase A4G23_RS09575 240574a0f853a3530c328a4209bcd877 166 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 3 117 1.4E-48 T 10-11-2016 IPR028973 PhnB-like A4G23_RS09575 240574a0f853a3530c328a4209bcd877 166 SUPERFAMILY SSF54593 4 155 1.13E-51 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS09575 240574a0f853a3530c328a4209bcd877 166 Gene3D G3DSA:3.10.180.10 1 129 1.9E-49 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS19940 2971b549b2931b39ffa485fae8fe99a5 455 Pfam PF03313 Serine dehydratase alpha chain 188 449 1.8E-105 T 10-11-2016 IPR005130 Serine dehydratase-like, alpha subunit A4G23_RS19940 2971b549b2931b39ffa485fae8fe99a5 455 TIGRFAM TIGR00720 sda_mono: L-serine ammonia-lyase 3 452 8.1E-213 T 10-11-2016 IPR004644 Iron-sulphur-dependent L-serine dehydratase single chain form GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 A4G23_RS19940 2971b549b2931b39ffa485fae8fe99a5 455 SUPERFAMILY SSF143548 17 159 1.02E-47 T 10-11-2016 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 A4G23_RS19940 2971b549b2931b39ffa485fae8fe99a5 455 Pfam PF03315 Serine dehydratase beta chain 4 157 6.5E-60 T 10-11-2016 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 A4G23_RS19940 2971b549b2931b39ffa485fae8fe99a5 455 Gene3D G3DSA:3.30.1330.90 11 159 4.1E-56 T 10-11-2016 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 A4G23_RS00905 92094272cc680de9a9ac0fac2235645a 282 SMART SM00382 32 219 6.1E-14 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS00905 92094272cc680de9a9ac0fac2235645a 282 SUPERFAMILY SSF52540 20 218 4.42E-52 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS00905 92094272cc680de9a9ac0fac2235645a 282 Gene3D G3DSA:3.40.50.300 4 231 3.3E-58 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS00905 92094272cc680de9a9ac0fac2235645a 282 TIGRFAM TIGR01166 cbiO: cobalt ABC transporter, ATP-binding protein 16 205 5.6E-88 T 10-11-2016 IPR005876 Cobalt transport protein ATP-binding subunit GO:0006824 A4G23_RS00905 92094272cc680de9a9ac0fac2235645a 282 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS00905 92094272cc680de9a9ac0fac2235645a 282 Pfam PF00005 ABC transporter 23 171 2.5E-28 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS10710 a3c74297377a3a35959bb5d919eeb435 760 Gene3D G3DSA:1.20.1640.10 508 722 1.0E-30 T 10-11-2016 A4G23_RS10710 a3c74297377a3a35959bb5d919eeb435 760 Gene3D G3DSA:1.20.1640.10 134 339 2.3E-33 T 10-11-2016 A4G23_RS10710 a3c74297377a3a35959bb5d919eeb435 760 SUPERFAMILY SSF82866 492 716 5.36E-27 T 10-11-2016 A4G23_RS10710 a3c74297377a3a35959bb5d919eeb435 760 SUPERFAMILY SSF82866 118 334 4.58E-31 T 10-11-2016 A4G23_RS10710 a3c74297377a3a35959bb5d919eeb435 760 Pfam PF03176 MMPL family 503 718 6.9E-29 T 10-11-2016 IPR004869 Membrane transport protein, MMPL domain GO:0016020 A4G23_RS10710 a3c74297377a3a35959bb5d919eeb435 760 Pfam PF03176 MMPL family 45 399 1.0E-81 T 10-11-2016 IPR004869 Membrane transport protein, MMPL domain GO:0016020 A4G23_RS16160 0099cdd9c1f9ea07c28e8fa3fad67801 350 SUPERFAMILY SSF52518 26 349 6.08E-85 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS16160 0099cdd9c1f9ea07c28e8fa3fad67801 350 Gene3D G3DSA:3.40.50.970 26 243 1.5E-83 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS16160 0099cdd9c1f9ea07c28e8fa3fad67801 350 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 62 209 9.0E-30 T 10-11-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A4G23_RS07520 2f3260611e39dadcf2f70eb1cd46dda9 287 Gene3D G3DSA:3.40.50.1110 43 181 2.8E-21 T 10-11-2016 IPR013830 SGNH hydrolase-type esterase domain A4G23_RS07520 2f3260611e39dadcf2f70eb1cd46dda9 287 Gene3D G3DSA:3.40.50.1110 217 280 2.8E-21 T 10-11-2016 IPR013830 SGNH hydrolase-type esterase domain A4G23_RS07520 2f3260611e39dadcf2f70eb1cd46dda9 287 SUPERFAMILY SSF52266 42 182 1.83E-24 T 10-11-2016 IPR013830 SGNH hydrolase-type esterase domain A4G23_RS07520 2f3260611e39dadcf2f70eb1cd46dda9 287 SUPERFAMILY SSF52266 211 279 1.83E-24 T 10-11-2016 IPR013830 SGNH hydrolase-type esterase domain A4G23_RS07520 2f3260611e39dadcf2f70eb1cd46dda9 287 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 48 269 1.7E-19 T 10-11-2016 IPR013830 SGNH hydrolase-type esterase domain A4G23_RS17050 a3c34beecd36f8816f457b012f5a9749 129 Pfam PF14431 YwqJ-like deaminase 4 124 3.7E-19 T 10-11-2016 IPR025968 YwqJ-like deaminase A4G23_RS20145 a6ecf1bd7b9949751b98370f071b2dad 308 SUPERFAMILY SSF51730 35 304 1.37E-67 T 10-11-2016 IPR029041 FAD-linked oxidoreductase-like A4G23_RS20145 a6ecf1bd7b9949751b98370f071b2dad 308 Gene3D G3DSA:3.20.20.220 35 302 5.5E-66 T 10-11-2016 IPR029041 FAD-linked oxidoreductase-like A4G23_RS20145 a6ecf1bd7b9949751b98370f071b2dad 308 Pfam PF01619 Proline dehydrogenase 47 298 6.5E-30 T 10-11-2016 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 A4G23_RS20145 a6ecf1bd7b9949751b98370f071b2dad 308 PIRSF PIRSF000196 1 308 3.0E-112 T 10-11-2016 IPR008219 Proline dehydrogenase GO:0004657|GO:0010133 KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 A4G23_RS04370 4aae96d452ab6da81f66dffb614c86ef 254 Pfam PF01614 Bacterial transcriptional regulator 123 247 1.8E-33 T 10-11-2016 IPR014757 Transcription regulator IclR, C-terminal A4G23_RS04370 4aae96d452ab6da81f66dffb614c86ef 254 Pfam PF09339 IclR helix-turn-helix domain 7 57 1.2E-16 T 10-11-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4G23_RS04370 4aae96d452ab6da81f66dffb614c86ef 254 SUPERFAMILY SSF55781 71 250 1.24E-36 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS04370 4aae96d452ab6da81f66dffb614c86ef 254 SMART SM00346 5 95 9.9E-35 T 10-11-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4G23_RS04370 4aae96d452ab6da81f66dffb614c86ef 254 SUPERFAMILY SSF46785 5 77 1.17E-16 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS04370 4aae96d452ab6da81f66dffb614c86ef 254 Gene3D G3DSA:3.30.450.40 75 250 7.5E-44 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS04370 4aae96d452ab6da81f66dffb614c86ef 254 Gene3D G3DSA:1.10.10.10 3 74 9.0E-23 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS23315 04f2017ad0b7f29d152dcffb4f1f5c2f 355 Pfam PF10935 Protein of unknown function (DUF2637) 70 217 4.2E-23 T 10-11-2016 IPR021235 Protein of unknown function DUF2637 A4G23_RS00770 68357d804323c69fbe903d420de8c296 230 Gene3D G3DSA:3.40.109.10 38 228 9.8E-45 T 10-11-2016 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4G23_RS00770 68357d804323c69fbe903d420de8c296 230 SUPERFAMILY SSF55469 38 228 2.22E-42 T 10-11-2016 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4G23_RS00770 68357d804323c69fbe903d420de8c296 230 Pfam PF00881 Nitroreductase family 44 208 1.1E-24 T 10-11-2016 IPR029479 Nitroreductase Reactome: R-HSA-209968 A4G23_RS03070 715904ffcaf5f91e9e9ff6d3b381e433 176 Pfam PF00498 FHA domain 100 163 5.3E-18 T 10-11-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 A4G23_RS03070 715904ffcaf5f91e9e9ff6d3b381e433 176 SUPERFAMILY SSF49879 52 170 4.59E-31 T 10-11-2016 IPR008984 SMAD/FHA domain GO:0005515 A4G23_RS03070 715904ffcaf5f91e9e9ff6d3b381e433 176 Gene3D G3DSA:2.60.200.20 77 171 2.0E-28 T 10-11-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 A4G23_RS03070 715904ffcaf5f91e9e9ff6d3b381e433 176 Pfam PF13240 zinc-ribbon domain 3 24 9.5E-6 T 10-11-2016 IPR026870 Zinc-ribbon domain A4G23_RS03070 715904ffcaf5f91e9e9ff6d3b381e433 176 SMART SM00240 98 149 3.0E-12 T 10-11-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 A4G23_RS23300 b83986281476fc36e31c9edb21047dac 328 SUPERFAMILY SSF46894 270 326 1.02E-8 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS23300 b83986281476fc36e31c9edb21047dac 328 SUPERFAMILY SSF46785 2 83 1.41E-6 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS23300 b83986281476fc36e31c9edb21047dac 328 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 2 68 1.2E-8 T 10-11-2016 IPR002831 Transcription regulator TrmB, N-terminal A4G23_RS23300 b83986281476fc36e31c9edb21047dac 328 SMART SM00421 263 320 1.2E-5 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS23300 b83986281476fc36e31c9edb21047dac 328 Gene3D G3DSA:1.10.10.10 2 64 2.5E-8 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS23300 b83986281476fc36e31c9edb21047dac 328 Gene3D G3DSA:1.10.10.10 271 326 1.3E-8 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS04185 626f4450c52cc8c99f0110a55bd9efa5 231 Gene3D G3DSA:3.40.50.880 9 215 2.8E-37 T 10-11-2016 IPR029062 Class I glutamine amidotransferase-like A4G23_RS04185 626f4450c52cc8c99f0110a55bd9efa5 231 SUPERFAMILY SSF52317 9 224 6.82E-37 T 10-11-2016 IPR029062 Class I glutamine amidotransferase-like A4G23_RS04185 626f4450c52cc8c99f0110a55bd9efa5 231 Pfam PF07722 Peptidase C26 10 214 4.6E-59 T 10-11-2016 IPR011697 Peptidase C26 GO:0006541|GO:0016787 A4G23_RS05140 26c4e3755d916d5eefc6bce18652f6b2 66 Pfam PF04149 Domain of unknown function (DUF397) 8 57 5.7E-21 T 10-11-2016 IPR007278 Domain of unknown function DUF397 A4G23_RS01030 d6eba9de2a3b4f926ac6f4931cfe753f 179 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 4 143 1.6E-32 T 10-11-2016 IPR006543 Histidinol-phosphate phosphatase GO:0016791 A4G23_RS01030 d6eba9de2a3b4f926ac6f4931cfe753f 179 SUPERFAMILY SSF56784 4 160 3.08E-43 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS01030 d6eba9de2a3b4f926ac6f4931cfe753f 179 Gene3D G3DSA:3.40.50.1000 4 157 1.6E-48 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS01030 d6eba9de2a3b4f926ac6f4931cfe753f 179 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 4 143 8.5E-33 T 10-11-2016 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 A4G23_RS01030 d6eba9de2a3b4f926ac6f4931cfe753f 179 PIRSF PIRSF004682 2 167 1.9E-43 T 10-11-2016 IPR004446 D,D-heptose 1,7-bisphosphate phosphatase GO:0005975|GO:0016791 A4G23_RS01030 d6eba9de2a3b4f926ac6f4931cfe753f 179 Pfam PF13242 HAD-hyrolase-like 96 152 1.6E-11 T 10-11-2016 A4G23_RS03245 c22e286256d91dbdb56855785e7674cb 269 Pfam PF13653 Glycerophosphoryl diester phosphodiesterase family 227 255 4.0E-7 T 10-11-2016 A4G23_RS03245 c22e286256d91dbdb56855785e7674cb 269 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 34 175 2.4E-23 T 10-11-2016 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 A4G23_RS03245 c22e286256d91dbdb56855785e7674cb 269 SUPERFAMILY SSF51695 28 262 2.59E-61 T 10-11-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 A4G23_RS03245 c22e286256d91dbdb56855785e7674cb 269 Gene3D G3DSA:3.20.20.190 25 268 1.1E-71 T 10-11-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 A4G23_RS25525 65a134c2ae4eae06d3a4713acc7e7ec8 180 Pfam PF12724 Flavodoxin domain 6 150 2.3E-26 T 10-11-2016 IPR026816 Flavodoxin domain A4G23_RS25525 65a134c2ae4eae06d3a4713acc7e7ec8 180 Gene3D G3DSA:3.40.50.360 6 165 5.9E-10 T 10-11-2016 IPR029039 Flavoprotein-like domain A4G23_RS25525 65a134c2ae4eae06d3a4713acc7e7ec8 180 SUPERFAMILY SSF52218 143 165 3.46E-12 T 10-11-2016 IPR029039 Flavoprotein-like domain A4G23_RS25525 65a134c2ae4eae06d3a4713acc7e7ec8 180 SUPERFAMILY SSF52218 5 115 3.46E-12 T 10-11-2016 IPR029039 Flavoprotein-like domain A4G23_RS25525 65a134c2ae4eae06d3a4713acc7e7ec8 180 ProSitePatterns PS00201 Flavodoxin signature. 6 22 - T 10-11-2016 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 A4G23_RS11015 325bb3c975ecbbcc203746a38ba81f89 145 Pfam PF13581 Histidine kinase-like ATPase domain 24 136 1.9E-13 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS11015 325bb3c975ecbbcc203746a38ba81f89 145 SUPERFAMILY SSF55874 45 138 7.94E-10 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS11015 325bb3c975ecbbcc203746a38ba81f89 145 Gene3D G3DSA:3.30.565.10 46 118 2.0E-4 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS23815 1870fb88ae7e14cbc55b6eb755420655 330 Gene3D G3DSA:3.50.50.60 231 310 2.3E-11 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS23815 1870fb88ae7e14cbc55b6eb755420655 330 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 297 3.4E-44 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS23815 1870fb88ae7e14cbc55b6eb755420655 330 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 7 308 1.9E-107 T 10-11-2016 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00240+1.8.1.9|KEGG: 00450+1.8.1.9 A4G23_RS23815 1870fb88ae7e14cbc55b6eb755420655 330 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 136 156 - T 10-11-2016 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 A4G23_RS23815 1870fb88ae7e14cbc55b6eb755420655 330 Gene3D G3DSA:3.50.50.60 6 119 7.8E-28 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS23815 1870fb88ae7e14cbc55b6eb755420655 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 271 289 1.8E-70 T 10-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4G23_RS23815 1870fb88ae7e14cbc55b6eb755420655 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 129 141 1.8E-70 T 10-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4G23_RS23815 1870fb88ae7e14cbc55b6eb755420655 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 40 55 1.8E-70 T 10-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4G23_RS23815 1870fb88ae7e14cbc55b6eb755420655 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 7 29 1.8E-70 T 10-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4G23_RS23815 1870fb88ae7e14cbc55b6eb755420655 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 144 168 1.8E-70 T 10-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4G23_RS23815 1870fb88ae7e14cbc55b6eb755420655 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 107 115 1.8E-70 T 10-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4G23_RS23815 1870fb88ae7e14cbc55b6eb755420655 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 196 212 1.8E-70 T 10-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4G23_RS23815 1870fb88ae7e14cbc55b6eb755420655 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 61 71 1.8E-70 T 10-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4G23_RS23815 1870fb88ae7e14cbc55b6eb755420655 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 236 257 1.8E-70 T 10-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4G23_RS23815 1870fb88ae7e14cbc55b6eb755420655 330 SUPERFAMILY SSF51905 6 308 4.68E-44 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS23815 1870fb88ae7e14cbc55b6eb755420655 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 234 250 3.2E-37 T 10-11-2016 A4G23_RS23815 1870fb88ae7e14cbc55b6eb755420655 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 3.2E-37 T 10-11-2016 A4G23_RS23815 1870fb88ae7e14cbc55b6eb755420655 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 3.2E-37 T 10-11-2016 A4G23_RS23815 1870fb88ae7e14cbc55b6eb755420655 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 148 166 3.2E-37 T 10-11-2016 A4G23_RS23815 1870fb88ae7e14cbc55b6eb755420655 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 283 3.2E-37 T 10-11-2016 A4G23_RS23815 1870fb88ae7e14cbc55b6eb755420655 330 Gene3D G3DSA:3.50.50.60 120 230 1.1E-31 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS00605 59ca25d4e9db6d786f4147eca1a5c6b1 431 Pfam PF14535 AMP-binding enzyme C-terminal domain 334 427 7.5E-26 T 10-11-2016 IPR028154 AMP-dependent ligase, C-terminal A4G23_RS00605 59ca25d4e9db6d786f4147eca1a5c6b1 431 Gene3D G3DSA:3.30.300.30 324 428 1.5E-36 T 10-11-2016 A4G23_RS00605 59ca25d4e9db6d786f4147eca1a5c6b1 431 SUPERFAMILY SSF56801 18 423 1.96E-64 T 10-11-2016 A4G23_RS00605 59ca25d4e9db6d786f4147eca1a5c6b1 431 TIGRFAM TIGR02155 PA_CoA_ligase: phenylacetate-CoA ligase 10 427 2.0E-214 T 10-11-2016 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 A4G23_RS00605 59ca25d4e9db6d786f4147eca1a5c6b1 431 Gene3D G3DSA:3.40.50.980 91 244 1.3E-12 T 10-11-2016 A4G23_RS00605 59ca25d4e9db6d786f4147eca1a5c6b1 431 Pfam PF00501 AMP-binding enzyme 92 288 2.9E-15 T 10-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A4G23_RS00605 59ca25d4e9db6d786f4147eca1a5c6b1 431 PIRSF PIRSF006444 1 429 1.4E-202 T 10-11-2016 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 A4G23_RS08720 0f70937160590caac4093ff46ef8992e 285 Pfam PF12679 ABC-2 family transporter protein 24 283 2.6E-9 T 10-11-2016 IPR032688 ABC-2 family transporter protein GO:0006810 A4G23_RS19430 877c314885a513277bbaf9907d0d400c 439 SUPERFAMILY SSF53850 41 411 3.26E-23 T 10-11-2016 A4G23_RS19430 877c314885a513277bbaf9907d0d400c 439 Pfam PF01547 Bacterial extracellular solute-binding protein 50 198 2.1E-10 T 10-11-2016 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 A4G23_RS19430 877c314885a513277bbaf9907d0d400c 439 Gene3D G3DSA:3.40.190.10 47 162 1.6E-11 T 10-11-2016 A4G23_RS07530 703906d5e968d31a2581fc421f697d74 374 SUPERFAMILY SSF53182 297 371 6.41E-25 T 10-11-2016 A4G23_RS07530 703906d5e968d31a2581fc421f697d74 374 SUPERFAMILY SSF53182 129 269 6.41E-25 T 10-11-2016 A4G23_RS07530 703906d5e968d31a2581fc421f697d74 374 Gene3D G3DSA:3.40.630.20 129 368 1.6E-9 T 10-11-2016 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like A4G23_RS03260 a8fc45ea5f6175f1a09e9d04b4687b96 182 Pfam PF04186 FxsA cytoplasmic membrane protein 24 135 2.9E-28 T 10-11-2016 IPR007313 FxsA cytoplasmic membrane protein GO:0016020 A4G23_RS19035 8f4ebb9124eadf2d719235857ed8b70c 487 Pfam PF07568 Histidine kinase 290 361 2.3E-22 T 10-11-2016 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain A4G23_RS19035 8f4ebb9124eadf2d719235857ed8b70c 487 Pfam PF12282 Signal transduction histidine kinase 1 144 5.4E-61 T 10-11-2016 IPR022066 Signal transduction histidine kinase A4G23_RS19035 8f4ebb9124eadf2d719235857ed8b70c 487 Gene3D G3DSA:3.30.450.20 173 281 1.3E-6 T 10-11-2016 A4G23_RS19035 8f4ebb9124eadf2d719235857ed8b70c 487 Pfam PF08448 PAS fold 172 276 3.8E-12 T 10-11-2016 IPR013656 PAS fold-4 A4G23_RS19035 8f4ebb9124eadf2d719235857ed8b70c 487 PRINTS PR00344 Bacterial sensor protein C-terminal signature 425 439 3.8E-5 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS19035 8f4ebb9124eadf2d719235857ed8b70c 487 PRINTS PR00344 Bacterial sensor protein C-terminal signature 444 462 3.8E-5 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS19035 8f4ebb9124eadf2d719235857ed8b70c 487 PRINTS PR00344 Bacterial sensor protein C-terminal signature 469 482 3.8E-5 T 10-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4G23_RS19035 8f4ebb9124eadf2d719235857ed8b70c 487 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 386 483 6.4E-12 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS19035 8f4ebb9124eadf2d719235857ed8b70c 487 Gene3D G3DSA:3.30.565.10 345 484 2.6E-17 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS19035 8f4ebb9124eadf2d719235857ed8b70c 487 SMART SM00387 382 485 6.5E-11 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS19035 8f4ebb9124eadf2d719235857ed8b70c 487 SUPERFAMILY SSF55785 173 281 1.48E-6 T 10-11-2016 IPR000014 PAS domain A4G23_RS19035 8f4ebb9124eadf2d719235857ed8b70c 487 SUPERFAMILY SSF55874 362 484 6.55E-19 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS01345 26e10daaf46b73f392cfcc10f30afcf9 303 Pfam PF00294 pfkB family carbohydrate kinase 7 295 7.2E-51 T 10-11-2016 IPR011611 Carbohydrate kinase PfkB A4G23_RS01345 26e10daaf46b73f392cfcc10f30afcf9 303 SUPERFAMILY SSF53613 1 303 4.99E-75 T 10-11-2016 IPR029056 Ribokinase-like A4G23_RS01345 26e10daaf46b73f392cfcc10f30afcf9 303 TIGRFAM TIGR04382 myo_inos_iolC_N: 5-dehydro-2-deoxygluconokinase 1 303 2.9E-108 T 10-11-2016 IPR030830 5-dehydro-2-deoxygluconokinase KEGG: 00562+2.7.1.92 A4G23_RS01345 26e10daaf46b73f392cfcc10f30afcf9 303 Gene3D G3DSA:3.40.1190.20 1 303 3.5E-100 T 10-11-2016 IPR029056 Ribokinase-like A4G23_RS14165 a1ede08d545f9d0d9021a7d441320f7e 359 SUPERFAMILY SSF48452 227 310 1.04E-8 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS14165 a1ede08d545f9d0d9021a7d441320f7e 359 Gene3D G3DSA:1.25.40.10 45 300 1.1E-18 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS14165 a1ede08d545f9d0d9021a7d441320f7e 359 SUPERFAMILY SSF48452 71 250 9.1E-13 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS07020 235cb18e8943fbaef7987e681ca0ef98 364 SUPERFAMILY SSF53335 67 107 5.15E-8 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS07020 235cb18e8943fbaef7987e681ca0ef98 364 SUPERFAMILY SSF53335 141 246 5.15E-8 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS07020 235cb18e8943fbaef7987e681ca0ef98 364 Pfam PF09243 Mitochondrial small ribosomal subunit Rsm22 53 110 2.5E-14 T 10-11-2016 IPR015324 Ribosomal protein Rsm22, bacterial-type GO:0006412|GO:0008168 A4G23_RS07020 235cb18e8943fbaef7987e681ca0ef98 364 Pfam PF09243 Mitochondrial small ribosomal subunit Rsm22 146 362 1.6E-81 T 10-11-2016 IPR015324 Ribosomal protein Rsm22, bacterial-type GO:0006412|GO:0008168 A4G23_RS01490 6676c810263f972505624a38ff102445 156 Gene3D G3DSA:3.30.70.1450 81 154 1.4E-18 T 10-11-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A4G23_RS01490 6676c810263f972505624a38ff102445 156 SUPERFAMILY SSF116726 78 154 6.41E-16 T 10-11-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A4G23_RS01490 6676c810263f972505624a38ff102445 156 Pfam PF02080 TrkA-C domain 85 154 8.5E-15 T 10-11-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A4G23_RS01490 6676c810263f972505624a38ff102445 156 PIRSF PIRSF005028 1 156 1.9E-51 T 10-11-2016 IPR026278 Potassium/proton antiporter subunit KhtT A4G23_RS15910 2235c22b7feb46c2f5f0dbd4b79d5a13 191 SUPERFAMILY SSF55729 17 190 4.32E-23 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS15910 2235c22b7feb46c2f5f0dbd4b79d5a13 191 Pfam PF13508 Acetyltransferase (GNAT) domain 87 165 3.6E-7 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS15910 2235c22b7feb46c2f5f0dbd4b79d5a13 191 Gene3D G3DSA:3.40.630.30 16 190 5.7E-29 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS01425 e3537291c3f1dadf07fb51d512a6fa80 445 Gene3D G3DSA:3.40.390.10 189 251 1.6E-4 T 10-11-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 A4G23_RS01425 e3537291c3f1dadf07fb51d512a6fa80 445 Pfam PF09471 IgA Peptidase M64 82 338 1.8E-64 T 10-11-2016 IPR019026 Peptidase M64, IgA A4G23_RS01730 8e6ddbec4529d9f8f41b0e3a2d1fb7c4 158 SUPERFAMILY SSF55811 10 137 1.04E-30 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS01730 8e6ddbec4529d9f8f41b0e3a2d1fb7c4 158 Pfam PF00293 NUDIX domain 22 134 7.5E-20 T 10-11-2016 IPR000086 NUDIX hydrolase domain GO:0016787 A4G23_RS01730 8e6ddbec4529d9f8f41b0e3a2d1fb7c4 158 Gene3D G3DSA:3.90.79.10 11 147 4.1E-31 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS08285 71ecc71468761fb83b045cd6cb18f90b 520 ProSitePatterns PS01012 Folylpolyglutamate synthase signature 2. 219 234 - T 10-11-2016 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 A4G23_RS08285 71ecc71468761fb83b045cd6cb18f90b 520 TIGRFAM TIGR01499 folC: bifunctional protein FolC 102 514 1.3E-98 T 10-11-2016 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 A4G23_RS08285 71ecc71468761fb83b045cd6cb18f90b 520 Gene3D G3DSA:3.90.190.20 380 519 3.5E-37 T 10-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4G23_RS08285 71ecc71468761fb83b045cd6cb18f90b 520 Pfam PF02875 Mur ligase family, glutamate ligase domain 379 459 1.1E-13 T 10-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4G23_RS08285 71ecc71468761fb83b045cd6cb18f90b 520 SUPERFAMILY SSF53623 81 376 1.32E-87 T 10-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4G23_RS08285 71ecc71468761fb83b045cd6cb18f90b 520 Pfam PF08245 Mur ligase middle domain 123 350 2.1E-15 T 10-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4G23_RS08285 71ecc71468761fb83b045cd6cb18f90b 520 Gene3D G3DSA:3.40.1190.10 92 377 3.0E-92 T 10-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4G23_RS08285 71ecc71468761fb83b045cd6cb18f90b 520 SUPERFAMILY SSF53244 380 517 7.51E-27 T 10-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4G23_RS10065 f2d848ac764cbddbc1b8f4eeb150e8fe 318 Gene3D G3DSA:2.60.120.620 5 273 5.0E-55 T 10-11-2016 A4G23_RS10065 f2d848ac764cbddbc1b8f4eeb150e8fe 318 SUPERFAMILY SSF51197 9 305 4.67E-56 T 10-11-2016 A4G23_RS10065 f2d848ac764cbddbc1b8f4eeb150e8fe 318 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 19 249 1.8E-37 T 10-11-2016 IPR008775 Phytanoyl-CoA dioxygenase A4G23_RS10065 f2d848ac764cbddbc1b8f4eeb150e8fe 318 TIGRFAM TIGR01762 chlorin-enz: chlorinating enzyme 9 303 4.1E-135 T 10-11-2016 IPR010092 Chlorinating enzyme A4G23_RS04555 ffe81cd675638f0de23b6e499b2161c8 404 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 134 235 5.8E-21 T 10-11-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 A4G23_RS04555 ffe81cd675638f0de23b6e499b2161c8 404 Gene3D G3DSA:1.20.140.10 239 403 1.6E-44 T 10-11-2016 A4G23_RS04555 ffe81cd675638f0de23b6e499b2161c8 404 Gene3D G3DSA:1.10.540.10 1 132 1.3E-34 T 10-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 A4G23_RS04555 ffe81cd675638f0de23b6e499b2161c8 404 SUPERFAMILY SSF56645 1 262 2.49E-64 T 10-11-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 A4G23_RS04555 ffe81cd675638f0de23b6e499b2161c8 404 SUPERFAMILY SSF47203 247 403 2.26E-41 T 10-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4G23_RS04555 ffe81cd675638f0de23b6e499b2161c8 404 Gene3D G3DSA:2.40.110.10 133 238 4.3E-39 T 10-11-2016 A4G23_RS04555 ffe81cd675638f0de23b6e499b2161c8 404 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 249 399 5.1E-33 T 10-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4G23_RS04555 ffe81cd675638f0de23b6e499b2161c8 404 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 130 1.6E-15 T 10-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 A4G23_RS23175 646a22876952cb9ba2d8b50bdcf23ba6 312 Gene3D G3DSA:3.40.50.620 253 261 7.7E-55 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS23175 646a22876952cb9ba2d8b50bdcf23ba6 312 Gene3D G3DSA:3.40.50.620 5 220 7.7E-55 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS23175 646a22876952cb9ba2d8b50bdcf23ba6 312 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 21 312 1.1E-139 T 10-11-2016 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 A4G23_RS23175 646a22876952cb9ba2d8b50bdcf23ba6 312 SUPERFAMILY SSF52402 17 220 2.3E-65 T 10-11-2016 A4G23_RS23175 646a22876952cb9ba2d8b50bdcf23ba6 312 PIRSF PIRSF002936 12 312 4.8E-138 T 10-11-2016 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 A4G23_RS23175 646a22876952cb9ba2d8b50bdcf23ba6 312 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 42 266 1.2E-50 T 10-11-2016 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 A4G23_RS23175 646a22876952cb9ba2d8b50bdcf23ba6 312 Hamap MF_00064 Sulfate adenylyltransferase subunit 2 [cysD]. 16 312 54.092 T 10-11-2016 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 A4G23_RS04020 349d7c75262c623bb7564b40072727ea 381 Gene3D G3DSA:3.30.565.10 272 375 3.8E-5 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS04020 349d7c75262c623bb7564b40072727ea 381 SUPERFAMILY SSF55874 282 376 6.74E-15 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS04020 349d7c75262c623bb7564b40072727ea 381 Pfam PF07730 Histidine kinase 180 246 2.8E-16 T 10-11-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4G23_RS04275 e4713a8e1baafe466fb7444390ece8e2 453 TIGRFAM TIGR03686 pupylate_PafA: Pup--protein ligase 3 453 1.2E-233 T 10-11-2016 IPR022279 Pup--protein ligase GO:0010498|GO:0016879|GO:0019941 A4G23_RS04275 e4713a8e1baafe466fb7444390ece8e2 453 Hamap MF_02111 Pup--protein ligase [pafA]. 1 453 50.464 T 10-11-2016 IPR022279 Pup--protein ligase GO:0010498|GO:0016879|GO:0019941 A4G23_RS04275 e4713a8e1baafe466fb7444390ece8e2 453 PIRSF PIRSF018077 1 453 3.8E-183 T 10-11-2016 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 A4G23_RS04275 e4713a8e1baafe466fb7444390ece8e2 453 Pfam PF03136 Pup-ligase protein 4 423 4.2E-158 T 10-11-2016 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 A4G23_RS23180 a2fe7f2ae2d17c84180b168d38ab3de5 177 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 1 175 33.969 T 10-11-2016 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 A4G23_RS23180 a2fe7f2ae2d17c84180b168d38ab3de5 177 Pfam PF01583 Adenylylsulphate kinase 3 159 6.8E-59 T 10-11-2016 A4G23_RS23180 a2fe7f2ae2d17c84180b168d38ab3de5 177 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 3 169 5.8E-58 T 10-11-2016 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 A4G23_RS23180 a2fe7f2ae2d17c84180b168d38ab3de5 177 Gene3D G3DSA:3.40.50.300 3 176 9.0E-65 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS23180 a2fe7f2ae2d17c84180b168d38ab3de5 177 SUPERFAMILY SSF52540 3 174 9.69E-35 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS23080 d575cd7c65214c9b1c1f1db4bc40f528 746 SUPERFAMILY SSF51011 632 743 4.6E-23 T 10-11-2016 A4G23_RS23080 d575cd7c65214c9b1c1f1db4bc40f528 746 Pfam PF00128 Alpha amylase, catalytic domain 189 276 1.7E-7 T 10-11-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A4G23_RS23080 d575cd7c65214c9b1c1f1db4bc40f528 746 Gene3D G3DSA:2.60.40.1180 631 744 3.2E-32 T 10-11-2016 IPR013780 Glycosyl hydrolase, all-beta A4G23_RS23080 d575cd7c65214c9b1c1f1db4bc40f528 746 Gene3D G3DSA:2.60.40.10 5 151 2.1E-53 T 10-11-2016 IPR013783 Immunoglobulin-like fold A4G23_RS23080 d575cd7c65214c9b1c1f1db4bc40f528 746 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 10 96 6.1E-16 T 10-11-2016 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 A4G23_RS23080 d575cd7c65214c9b1c1f1db4bc40f528 746 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 6 551 4.8E-272 T 10-11-2016 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 A4G23_RS23080 d575cd7c65214c9b1c1f1db4bc40f528 746 SUPERFAMILY SSF81296 5 147 1.46E-42 T 10-11-2016 IPR014756 Immunoglobulin E-set A4G23_RS23080 d575cd7c65214c9b1c1f1db4bc40f528 746 SUPERFAMILY SSF51445 500 617 8.45E-129 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS23080 d575cd7c65214c9b1c1f1db4bc40f528 746 SUPERFAMILY SSF51445 133 471 8.45E-129 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS23080 d575cd7c65214c9b1c1f1db4bc40f528 746 SMART SM00642 132 596 2.9E-7 T 10-11-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A4G23_RS23080 d575cd7c65214c9b1c1f1db4bc40f528 746 Gene3D G3DSA:3.20.20.80 591 617 1.6E-118 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS23080 d575cd7c65214c9b1c1f1db4bc40f528 746 Gene3D G3DSA:3.20.20.80 152 549 1.6E-118 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS20865 03e4034343b40bdb90f24f2d5a2bf79c 356 PRINTS PR00721 Stomatin signature 77 98 6.0E-55 T 10-11-2016 IPR001972 Stomatin family GO:0016020 A4G23_RS20865 03e4034343b40bdb90f24f2d5a2bf79c 356 PRINTS PR00721 Stomatin signature 29 51 6.0E-55 T 10-11-2016 IPR001972 Stomatin family GO:0016020 A4G23_RS20865 03e4034343b40bdb90f24f2d5a2bf79c 356 PRINTS PR00721 Stomatin signature 200 223 6.0E-55 T 10-11-2016 IPR001972 Stomatin family GO:0016020 A4G23_RS20865 03e4034343b40bdb90f24f2d5a2bf79c 356 PRINTS PR00721 Stomatin signature 132 155 6.0E-55 T 10-11-2016 IPR001972 Stomatin family GO:0016020 A4G23_RS20865 03e4034343b40bdb90f24f2d5a2bf79c 356 PRINTS PR00721 Stomatin signature 112 129 6.0E-55 T 10-11-2016 IPR001972 Stomatin family GO:0016020 A4G23_RS20865 03e4034343b40bdb90f24f2d5a2bf79c 356 PRINTS PR00721 Stomatin signature 175 196 6.0E-55 T 10-11-2016 IPR001972 Stomatin family GO:0016020 A4G23_RS20865 03e4034343b40bdb90f24f2d5a2bf79c 356 PRINTS PR00721 Stomatin signature 156 174 6.0E-55 T 10-11-2016 IPR001972 Stomatin family GO:0016020 A4G23_RS20865 03e4034343b40bdb90f24f2d5a2bf79c 356 SUPERFAMILY SSF117892 54 187 4.97E-40 T 10-11-2016 IPR001107 Band 7 domain A4G23_RS20865 03e4034343b40bdb90f24f2d5a2bf79c 356 SMART SM00244 22 180 9.5E-63 T 10-11-2016 IPR001107 Band 7 domain A4G23_RS20865 03e4034343b40bdb90f24f2d5a2bf79c 356 Pfam PF01145 SPFH domain / Band 7 family 26 196 1.4E-33 T 10-11-2016 IPR001107 Band 7 domain A4G23_RS02595 3ef34b47c04fd3e56bda2d235818ae23 226 Pfam PF08241 Methyltransferase domain 53 145 1.4E-15 T 10-11-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 A4G23_RS02595 3ef34b47c04fd3e56bda2d235818ae23 226 Gene3D G3DSA:3.40.50.150 32 201 1.0E-24 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS02595 3ef34b47c04fd3e56bda2d235818ae23 226 SUPERFAMILY SSF53335 48 222 5.16E-31 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS14050 c53a1c000a47d3b4ab732187eea5c017 138 Gene3D G3DSA:3.10.180.10 4 126 1.0E-24 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS14050 c53a1c000a47d3b4ab732187eea5c017 138 SUPERFAMILY SSF54593 4 124 1.24E-20 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS14050 c53a1c000a47d3b4ab732187eea5c017 138 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 119 2.3E-6 T 10-11-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4G23_RS04730 516e7176fa6c887f7283935a343b6a51 157 SUPERFAMILY SSF159234 41 148 1.01E-14 T 10-11-2016 A4G23_RS04730 516e7176fa6c887f7283935a343b6a51 157 Pfam PF04167 Protein of unknown function (DUF402) 56 123 7.7E-20 T 10-11-2016 IPR007295 Domain of unknown function DUF402 A4G23_RS04730 516e7176fa6c887f7283935a343b6a51 157 Gene3D G3DSA:2.40.380.10 3 153 1.7E-40 T 10-11-2016 IPR007295 Domain of unknown function DUF402 A4G23_RS15845 3b96d10bb9d4c18c0b34539a2b880738 593 Pfam PF05140 ResB-like family 92 572 2.8E-127 T 10-11-2016 IPR007816 ResB-like domain A4G23_RS01245 ea6b22dccea8fcd60d95ba866745cfed 293 SUPERFAMILY SSF52402 160 292 5.86E-21 T 10-11-2016 A4G23_RS01245 ea6b22dccea8fcd60d95ba866745cfed 293 PRINTS PR01438 Universal stress protein signature 2 20 1.6E-10 T 10-11-2016 IPR006015 Universal stress protein A A4G23_RS01245 ea6b22dccea8fcd60d95ba866745cfed 293 PRINTS PR01438 Universal stress protein signature 114 136 1.6E-10 T 10-11-2016 IPR006015 Universal stress protein A A4G23_RS01245 ea6b22dccea8fcd60d95ba866745cfed 293 PRINTS PR01438 Universal stress protein signature 96 108 1.6E-10 T 10-11-2016 IPR006015 Universal stress protein A A4G23_RS01245 ea6b22dccea8fcd60d95ba866745cfed 293 Pfam PF00582 Universal stress protein family 153 291 8.0E-16 T 10-11-2016 IPR006016 UspA GO:0006950 A4G23_RS01245 ea6b22dccea8fcd60d95ba866745cfed 293 Pfam PF00582 Universal stress protein family 1 136 8.9E-22 T 10-11-2016 IPR006016 UspA GO:0006950 A4G23_RS01245 ea6b22dccea8fcd60d95ba866745cfed 293 Gene3D G3DSA:3.40.50.620 150 291 7.3E-23 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS01245 ea6b22dccea8fcd60d95ba866745cfed 293 Gene3D G3DSA:3.40.50.620 1 136 8.4E-31 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS01245 ea6b22dccea8fcd60d95ba866745cfed 293 SUPERFAMILY SSF52402 5 141 4.69E-26 T 10-11-2016 A4G23_RS23400 e593b50b679f166ad39a89476b67c4c2 407 Gene3D G3DSA:2.130.10.10 5 102 6.4E-9 T 10-11-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 A4G23_RS23400 e593b50b679f166ad39a89476b67c4c2 407 Gene3D G3DSA:2.130.10.10 264 393 6.4E-9 T 10-11-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 A4G23_RS23400 e593b50b679f166ad39a89476b67c4c2 407 SUPERFAMILY SSF51004 4 162 8.11E-10 T 10-11-2016 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain A4G23_RS23400 e593b50b679f166ad39a89476b67c4c2 407 SUPERFAMILY SSF51004 261 384 8.11E-10 T 10-11-2016 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain A4G23_RS13380 e7f26529e9da4581e1bdba4109e5edf8 292 Gene3D G3DSA:1.20.1540.10 79 256 5.6E-40 T 10-11-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 A4G23_RS13380 e7f26529e9da4581e1bdba4109e5edf8 292 Pfam PF01694 Rhomboid family 124 258 8.4E-37 T 10-11-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 A4G23_RS13380 e7f26529e9da4581e1bdba4109e5edf8 292 SUPERFAMILY SSF144091 79 261 9.55E-41 T 10-11-2016 A4G23_RS25515 177721609dcc819b36a3f1c4a5cb3f07 784 Pfam PF13549 ATP-grasp domain 613 770 1.5E-48 T 10-11-2016 A4G23_RS25515 177721609dcc819b36a3f1c4a5cb3f07 784 Gene3D G3DSA:3.40.50.720 183 310 6.0E-32 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS25515 177721609dcc819b36a3f1c4a5cb3f07 784 SMART SM00881 192 287 2.0E-27 T 10-11-2016 IPR003781 CoA-binding GO:0048037 A4G23_RS25515 177721609dcc819b36a3f1c4a5cb3f07 784 SUPERFAMILY SSF56059 606 770 5.3E-21 T 10-11-2016 A4G23_RS25515 177721609dcc819b36a3f1c4a5cb3f07 784 Gene3D G3DSA:3.40.50.261 468 569 2.9E-7 T 10-11-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4G23_RS25515 177721609dcc819b36a3f1c4a5cb3f07 784 Pfam PF13420 Acetyltransferase (GNAT) domain 20 157 4.5E-8 T 10-11-2016 A4G23_RS25515 177721609dcc819b36a3f1c4a5cb3f07 784 SUPERFAMILY SSF52210 310 478 4.19E-33 T 10-11-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4G23_RS25515 177721609dcc819b36a3f1c4a5cb3f07 784 SUPERFAMILY SSF55729 15 157 1.05E-23 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS25515 177721609dcc819b36a3f1c4a5cb3f07 784 Gene3D G3DSA:3.40.50.261 311 467 1.1E-24 T 10-11-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4G23_RS25515 177721609dcc819b36a3f1c4a5cb3f07 784 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 334 471 3.7E-40 T 10-11-2016 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain A4G23_RS25515 177721609dcc819b36a3f1c4a5cb3f07 784 Pfam PF13380 CoA binding domain 196 315 8.8E-18 T 10-11-2016 IPR003781 CoA-binding GO:0048037 A4G23_RS25515 177721609dcc819b36a3f1c4a5cb3f07 784 SUPERFAMILY SSF51735 185 318 2.41E-29 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS25515 177721609dcc819b36a3f1c4a5cb3f07 784 SUPERFAMILY SSF52210 477 598 8.63E-24 T 10-11-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A4G23_RS25515 177721609dcc819b36a3f1c4a5cb3f07 784 Gene3D G3DSA:3.40.630.30 13 163 9.1E-23 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS13965 b7062628cda7aebddf6d3b5c39d22041 142 SUPERFAMILY SSF53927 1 140 1.54E-53 T 10-11-2016 IPR016193 Cytidine deaminase-like GO:0003824 A4G23_RS13965 b7062628cda7aebddf6d3b5c39d22041 142 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 1 142 47.343 T 10-11-2016 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 A4G23_RS13965 b7062628cda7aebddf6d3b5c39d22041 142 Pfam PF14437 MafB19-like deaminase 1 140 2.4E-32 T 10-11-2016 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 A4G23_RS13965 b7062628cda7aebddf6d3b5c39d22041 142 Gene3D G3DSA:3.40.140.10 1 141 4.1E-61 T 10-11-2016 A4G23_RS13965 b7062628cda7aebddf6d3b5c39d22041 142 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 47 84 - T 10-11-2016 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 A4G23_RS18255 140f5da4569b89aa6459451e0960658d 234 Pfam PF09922 Cell wall-active antibiotics response 4TMS YvqF 132 190 2.1E-7 T 10-11-2016 IPR024425 Cell wall-active antibiotics response 4TMS YvqF A4G23_RS18255 140f5da4569b89aa6459451e0960658d 234 Pfam PF08044 Domain of unknown function (DUF1707) 26 78 3.3E-23 T 10-11-2016 IPR012551 Protein of unknown function DUF1707 A4G23_RS25800 3abf5a1df3df17445a6e802f48b5aace 270 Pfam PF04672 S-adenosyl methyltransferase 5 269 2.7E-101 T 10-11-2016 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type A4G23_RS25800 3abf5a1df3df17445a6e802f48b5aace 270 Gene3D G3DSA:3.40.50.150 2 269 3.8E-109 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS25800 3abf5a1df3df17445a6e802f48b5aace 270 PIRSF PIRSF017393 1 270 2.5E-98 T 10-11-2016 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type A4G23_RS25800 3abf5a1df3df17445a6e802f48b5aace 270 SUPERFAMILY SSF53335 16 257 3.24E-45 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS06160 82bce12c3bcc0d19bccba5f2e02bc646 335 Gene3D G3DSA:3.40.390.10 205 317 1.3E-11 T 10-11-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 A4G23_RS06160 82bce12c3bcc0d19bccba5f2e02bc646 335 Pfam PF05572 Pregnancy-associated plasma protein-A 210 327 3.2E-16 T 10-11-2016 IPR008754 Peptidase M43, pregnancy-associated plasma-A Reactome: R-HSA-381426 A4G23_RS06160 82bce12c3bcc0d19bccba5f2e02bc646 335 SUPERFAMILY SSF55486 163 328 1.87E-24 T 10-11-2016 A4G23_RS00100 6d18f87782b4eacf7bc5bd5168afdda8 66 Pfam PF00872 Transposase, Mutator family 1 33 1.6E-4 T 10-11-2016 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 A4G23_RS27340 6d18f87782b4eacf7bc5bd5168afdda8 66 Pfam PF00872 Transposase, Mutator family 1 33 1.6E-4 T 10-11-2016 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 A4G23_RS23490 334a54e65bffa9e14ae8761d29334c46 332 Gene3D G3DSA:3.30.465.10 157 219 8.5E-35 T 10-11-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 A4G23_RS23490 334a54e65bffa9e14ae8761d29334c46 332 Gene3D G3DSA:3.30.465.10 58 113 8.5E-35 T 10-11-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 A4G23_RS23490 334a54e65bffa9e14ae8761d29334c46 332 Gene3D G3DSA:3.30.390.50 225 323 2.8E-29 T 10-11-2016 A4G23_RS23490 334a54e65bffa9e14ae8761d29334c46 332 SUPERFAMILY SSF55447 225 323 4.19E-24 T 10-11-2016 IPR005107 CO dehydrogenase flavoprotein, C-terminal A4G23_RS23490 334a54e65bffa9e14ae8761d29334c46 332 SMART SM01092 226 325 1.2E-25 T 10-11-2016 IPR005107 CO dehydrogenase flavoprotein, C-terminal A4G23_RS23490 334a54e65bffa9e14ae8761d29334c46 332 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 3 219 3.2E-54 T 10-11-2016 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 A4G23_RS23490 334a54e65bffa9e14ae8761d29334c46 332 Gene3D G3DSA:3.30.43.10 2 51 1.3E-20 T 10-11-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 A4G23_RS23490 334a54e65bffa9e14ae8761d29334c46 332 SUPERFAMILY SSF56176 2 219 1.09E-61 T 10-11-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 A4G23_RS23490 334a54e65bffa9e14ae8761d29334c46 332 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 226 321 2.4E-17 T 10-11-2016 IPR005107 CO dehydrogenase flavoprotein, C-terminal A4G23_RS05290 162b19c2e2e8256c3082cc7d42f86e0f 316 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 311 92.654 T 10-11-2016 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 A4G23_RS05290 162b19c2e2e8256c3082cc7d42f86e0f 316 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 15 286 6.1E-50 T 10-11-2016 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 A4G23_RS05290 162b19c2e2e8256c3082cc7d42f86e0f 316 Pfam PF03186 CobD/Cbib protein 13 289 6.6E-85 T 10-11-2016 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 A4G23_RS08625 975d4a62f6a4e5cbb3c46d6363e407e2 154 ProSitePatterns PS00893 Nudix box signature. 48 69 - T 10-11-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A4G23_RS08625 975d4a62f6a4e5cbb3c46d6363e407e2 154 Gene3D G3DSA:3.90.79.10 13 123 1.4E-31 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS08625 975d4a62f6a4e5cbb3c46d6363e407e2 154 Pfam PF00293 NUDIX domain 18 124 3.9E-18 T 10-11-2016 IPR000086 NUDIX hydrolase domain GO:0016787 A4G23_RS08625 975d4a62f6a4e5cbb3c46d6363e407e2 154 SUPERFAMILY SSF55811 1 137 1.9E-32 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS08625 975d4a62f6a4e5cbb3c46d6363e407e2 154 PRINTS PR00502 NUDIX hydrolase family signature 43 57 9.3E-7 T 10-11-2016 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A4G23_RS08625 975d4a62f6a4e5cbb3c46d6363e407e2 154 PRINTS PR00502 NUDIX hydrolase family signature 57 72 9.3E-7 T 10-11-2016 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A4G23_RS17330 118dc5768cd3c25b75a6f31ae771de5a 331 Pfam PF03631 Virulence factor BrkB 33 283 8.7E-48 T 10-11-2016 IPR017039 Virulence factor BrkB A4G23_RS19585 71ef21b994dc3aae7601c94128abcb9f 148 Pfam PF10739 Protein of unknown function (DUF2550) 12 142 5.5E-44 T 10-11-2016 IPR019675 Protein of unknown function DUF2550 A4G23_RS16150 ea750b84e5453531d3aea3c2dd3f8a8b 151 Gene3D G3DSA:3.10.180.10 11 150 1.0E-11 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS16150 ea750b84e5453531d3aea3c2dd3f8a8b 151 SUPERFAMILY SSF54593 62 150 1.09E-10 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS16150 ea750b84e5453531d3aea3c2dd3f8a8b 151 SUPERFAMILY SSF54593 8 35 1.09E-10 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS07075 790da8e85625f26f6156afa9dfdd961b 288 Gene3D G3DSA:1.10.260.40 21 78 1.5E-13 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS07075 790da8e85625f26f6156afa9dfdd961b 288 SMART SM00530 29 84 1.1E-10 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS07075 790da8e85625f26f6156afa9dfdd961b 288 Pfam PF13560 Helix-turn-helix domain 26 85 9.4E-16 T 10-11-2016 A4G23_RS07075 790da8e85625f26f6156afa9dfdd961b 288 SUPERFAMILY SSF47413 23 78 2.15E-12 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS25090 fde3168ecc9f04d77d176e51ccd196e9 231 Gene3D G3DSA:3.40.50.150 11 213 1.0E-30 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS25090 fde3168ecc9f04d77d176e51ccd196e9 231 Pfam PF13847 Methyltransferase domain 48 157 1.3E-16 T 10-11-2016 IPR025714 Methyltransferase domain A4G23_RS25090 fde3168ecc9f04d77d176e51ccd196e9 231 SUPERFAMILY SSF53335 9 215 2.17E-37 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS10110 4ba2b9f67013139995d8d9b78aaee832 183 Pfam PF04138 GtrA-like protein 20 140 2.3E-23 T 10-11-2016 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 A4G23_RS00440 a66688f3d497e5a7c059d2e4c9b5711e 409 Gene3D G3DSA:3.40.50.2000 2 262 9.8E-53 T 10-11-2016 A4G23_RS00440 a66688f3d497e5a7c059d2e4c9b5711e 409 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 1 65 1.9E-7 T 10-11-2016 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4G23_RS00440 a66688f3d497e5a7c059d2e4c9b5711e 409 SUPERFAMILY SSF53756 2 408 1.08E-72 T 10-11-2016 A4G23_RS23695 b76602276e46646d629e0f5c840f37f3 1249 Gene3D G3DSA:3.40.50.740 608 792 2.3E-52 T 10-11-2016 A4G23_RS23695 b76602276e46646d629e0f5c840f37f3 1249 Gene3D G3DSA:3.90.55.10 793 849 3.2E-6 T 10-11-2016 A4G23_RS23695 b76602276e46646d629e0f5c840f37f3 1249 SMART SM00926 57 119 1.9E-5 T 10-11-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS23695 b76602276e46646d629e0f5c840f37f3 1249 Gene3D G3DSA:3.40.228.10 508 607 4.2E-84 T 10-11-2016 A4G23_RS23695 b76602276e46646d629e0f5c840f37f3 1249 Gene3D G3DSA:3.40.228.10 235 351 4.2E-84 T 10-11-2016 A4G23_RS23695 b76602276e46646d629e0f5c840f37f3 1249 Pfam PF01568 Molydopterin dinucleotide binding domain 1103 1213 8.1E-21 T 10-11-2016 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 A4G23_RS23695 b76602276e46646d629e0f5c840f37f3 1249 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 62 80 - T 10-11-2016 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 A4G23_RS23695 b76602276e46646d629e0f5c840f37f3 1249 TIGRFAM TIGR01580 narG: nitrate reductase, alpha subunit 29 1243 0.0 T 10-11-2016 IPR006468 Nitrate reductase, alpha subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.99.4 A4G23_RS23695 b76602276e46646d629e0f5c840f37f3 1249 Gene3D G3DSA:2.20.25.90 66 112 2.4E-29 T 10-11-2016 A4G23_RS23695 b76602276e46646d629e0f5c840f37f3 1249 Gene3D G3DSA:2.40.40.20 1071 1242 4.3E-39 T 10-11-2016 A4G23_RS23695 b76602276e46646d629e0f5c840f37f3 1249 Pfam PF00384 Molybdopterin oxidoreductase 122 845 2.3E-140 T 10-11-2016 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS23695 b76602276e46646d629e0f5c840f37f3 1249 Gene3D G3DSA:3.40.50.740 156 220 3.8E-5 T 10-11-2016 A4G23_RS23695 b76602276e46646d629e0f5c840f37f3 1249 SUPERFAMILY SSF50692 1097 1243 2.71E-43 T 10-11-2016 IPR009010 Aspartate decarboxylase-like domain A4G23_RS23695 b76602276e46646d629e0f5c840f37f3 1249 SUPERFAMILY SSF53706 23 1083 0.0 T 10-11-2016 A4G23_RS24305 d1ec21eff82635fce6ed8265dd075658 191 Gene3D G3DSA:1.25.10.10 48 169 1.6E-8 T 10-11-2016 IPR011989 Armadillo-like helical A4G23_RS24305 d1ec21eff82635fce6ed8265dd075658 191 SUPERFAMILY SSF48371 47 170 2.01E-8 T 10-11-2016 IPR016024 Armadillo-type fold GO:0005488 A4G23_RS24305 d1ec21eff82635fce6ed8265dd075658 191 SMART SM00567 E-Z type HEAT repeats 145 173 120.0 T 10-11-2016 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 A4G23_RS24305 d1ec21eff82635fce6ed8265dd075658 191 SMART SM00567 E-Z type HEAT repeats 45 74 4.3 T 10-11-2016 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 A4G23_RS24305 d1ec21eff82635fce6ed8265dd075658 191 SMART SM00567 E-Z type HEAT repeats 106 137 810.0 T 10-11-2016 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 A4G23_RS21350 75ff5fe030135354121d3243d9b0c77f 563 Gene3D G3DSA:1.20.1250.20 482 506 1.8E-11 T 10-11-2016 A4G23_RS21350 75ff5fe030135354121d3243d9b0c77f 563 Gene3D G3DSA:1.20.1250.20 266 428 1.8E-11 T 10-11-2016 A4G23_RS21350 75ff5fe030135354121d3243d9b0c77f 563 SUPERFAMILY SSF103473 481 506 1.31E-55 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS21350 75ff5fe030135354121d3243d9b0c77f 563 SUPERFAMILY SSF103473 12 206 1.31E-55 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS21350 75ff5fe030135354121d3243d9b0c77f 563 SUPERFAMILY SSF103473 256 427 1.31E-55 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS21350 75ff5fe030135354121d3243d9b0c77f 563 Pfam PF07690 Major Facilitator Superfamily 30 417 3.1E-45 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS21350 75ff5fe030135354121d3243d9b0c77f 563 Gene3D G3DSA:1.20.1250.20 17 202 1.0E-27 T 10-11-2016 A4G23_RS25710 036b955a5aec6950441fcd86020704cb 184 PIRSF PIRSF010260 2 184 3.3E-57 T 10-11-2016 IPR014457 Uncharacterised conserved protein UCP010260 A4G23_RS25710 036b955a5aec6950441fcd86020704cb 184 Pfam PF09348 Domain of unknown function (DUF1990) 20 176 1.2E-55 T 10-11-2016 IPR018960 Domain of unknown function DUF1990 A4G23_RS01600 361e04d91898d050c98e0f2a5f82e35b 173 SUPERFAMILY SSF46689 11 90 2.86E-15 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS01600 361e04d91898d050c98e0f2a5f82e35b 173 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 66 6.0E-12 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS01600 361e04d91898d050c98e0f2a5f82e35b 173 Gene3D G3DSA:1.10.357.10 13 144 6.7E-20 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS01600 361e04d91898d050c98e0f2a5f82e35b 173 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 3.5E-5 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS01600 361e04d91898d050c98e0f2a5f82e35b 173 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 3.5E-5 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS17000 a9710df149ba2212b350946adb354ef4 1012 Gene3D G3DSA:3.30.200.20 94 187 4.8E-9 T 10-11-2016 A4G23_RS17000 a9710df149ba2212b350946adb354ef4 1012 SUPERFAMILY SSF56112 599 733 2.76E-29 T 10-11-2016 IPR011009 Protein kinase-like domain A4G23_RS17000 a9710df149ba2212b350946adb354ef4 1012 SUPERFAMILY SSF56112 122 223 2.76E-29 T 10-11-2016 IPR011009 Protein kinase-like domain A4G23_RS17000 a9710df149ba2212b350946adb354ef4 1012 Pfam PF00069 Protein kinase domain 125 217 1.1E-7 T 10-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4G23_RS17000 a9710df149ba2212b350946adb354ef4 1012 SMART SM00220 60 694 1.4E-8 T 10-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4G23_RS17000 a9710df149ba2212b350946adb354ef4 1012 Gene3D G3DSA:1.10.510.10 586 706 5.4E-19 T 10-11-2016 A4G23_RS17000 a9710df149ba2212b350946adb354ef4 1012 Gene3D G3DSA:1.10.510.10 188 223 5.4E-19 T 10-11-2016 A4G23_RS04255 abb09ed6d66c096c50b5d7aa98d48faa 318 Pfam PF13280 WYL domain 144 311 6.8E-30 T 10-11-2016 IPR026881 WYL domain A4G23_RS04255 abb09ed6d66c096c50b5d7aa98d48faa 318 PIRSF PIRSF016838 2 318 3.9E-86 T 10-11-2016 IPR028349 Protein PafC A4G23_RS07315 2b55327246c6ba7e06fa8f884e7f34ce 427 SUPERFAMILY SSF47413 7 72 8.61E-8 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS07315 2b55327246c6ba7e06fa8f884e7f34ce 427 Gene3D G3DSA:1.10.260.40 11 73 3.8E-7 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS07315 2b55327246c6ba7e06fa8f884e7f34ce 427 Pfam PF13560 Helix-turn-helix domain 10 72 4.9E-12 T 10-11-2016 A4G23_RS07315 2b55327246c6ba7e06fa8f884e7f34ce 427 SMART SM00530 13 69 0.0031 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS07315 2b55327246c6ba7e06fa8f884e7f34ce 427 PRINTS PR01217 Proline rich extensin signature 143 164 2.3E-10 T 10-11-2016 A4G23_RS07315 2b55327246c6ba7e06fa8f884e7f34ce 427 PRINTS PR01217 Proline rich extensin signature 128 140 2.3E-10 T 10-11-2016 A4G23_RS07315 2b55327246c6ba7e06fa8f884e7f34ce 427 PRINTS PR01217 Proline rich extensin signature 108 124 2.3E-10 T 10-11-2016 A4G23_RS07315 2b55327246c6ba7e06fa8f884e7f34ce 427 PRINTS PR01217 Proline rich extensin signature 94 106 2.3E-10 T 10-11-2016 A4G23_RS18370 3e59f859113ebf04a943a6b09ac25921 347 Pfam PF13828 Domain of unknown function (DUF4190) 17 71 4.8E-14 T 10-11-2016 IPR025241 Domain of unknown function DUF4190 A4G23_RS18370 3e59f859113ebf04a943a6b09ac25921 347 Pfam PF13845 Septum formation 86 201 1.4E-11 T 10-11-2016 IPR026004 Septum formation-related domain A4G23_RS16615 0b871b761fe5991eb0d797d2f2ef7b14 107 ProSitePatterns PS00050 Ribosomal protein L23 signature. 87 102 - T 10-11-2016 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS16615 0b871b761fe5991eb0d797d2f2ef7b14 107 SUPERFAMILY SSF54189 12 104 9.35E-34 T 10-11-2016 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS16615 0b871b761fe5991eb0d797d2f2ef7b14 107 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 15 104 23.119 T 10-11-2016 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 A4G23_RS16615 0b871b761fe5991eb0d797d2f2ef7b14 107 Pfam PF00276 Ribosomal protein L23 16 101 6.8E-33 T 10-11-2016 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 A4G23_RS16615 0b871b761fe5991eb0d797d2f2ef7b14 107 Gene3D G3DSA:3.30.70.330 13 103 2.9E-37 T 10-11-2016 IPR012677 Nucleotide-binding alpha-beta plait domain GO:0000166 A4G23_RS05630 5f80c758a0b5f1e97943dcd067398cea 390 TIGRFAM TIGR00534 OpcA: glucose-6-phosphate dehydrogenase assembly protein OpcA 1 300 4.3E-95 T 10-11-2016 IPR004555 Glucose-6-phosphate dehydrogenase assembly protein OpcA A4G23_RS05630 5f80c758a0b5f1e97943dcd067398cea 390 Pfam PF10128 Glucose-6-phosphate dehydrogenase subunit 51 299 3.1E-81 T 10-11-2016 IPR004555 Glucose-6-phosphate dehydrogenase assembly protein OpcA A4G23_RS01420 e64083ac3cbfe99293f28b973cbe44f4 495 Gene3D G3DSA:3.40.50.1820 275 487 9.6E-24 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS01420 e64083ac3cbfe99293f28b973cbe44f4 495 Gene3D G3DSA:3.40.50.1820 3 240 4.2E-29 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS01420 e64083ac3cbfe99293f28b973cbe44f4 495 SUPERFAMILY SSF53474 5 238 2.62E-17 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS01420 e64083ac3cbfe99293f28b973cbe44f4 495 SUPERFAMILY SSF53474 276 483 9.73E-26 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS03410 994a37a3ee5fd0d9ea57fab7c4df1ae3 478 Pfam PF00860 Permease family 36 406 1.6E-70 T 10-11-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 A4G23_RS12185 6c12080dc66c05d23c044680fda56c74 164 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 9 162 30.519 T 10-11-2016 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 A4G23_RS12185 6c12080dc66c05d23c044680fda56c74 164 Pfam PF02542 YgbB family 11 160 6.3E-45 T 10-11-2016 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 A4G23_RS12185 6c12080dc66c05d23c044680fda56c74 164 Gene3D G3DSA:3.30.1330.50 10 162 1.1E-53 T 10-11-2016 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 A4G23_RS12185 6c12080dc66c05d23c044680fda56c74 164 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 44 59 - T 10-11-2016 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 A4G23_RS12185 6c12080dc66c05d23c044680fda56c74 164 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 11 161 6.0E-44 T 10-11-2016 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 A4G23_RS12185 6c12080dc66c05d23c044680fda56c74 164 SUPERFAMILY SSF69765 10 162 4.32E-48 T 10-11-2016 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 A4G23_RS06895 ee6ab4a723e8a111c52ee29f26b290cf 457 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 164 236 1.1E-10 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS06895 ee6ab4a723e8a111c52ee29f26b290cf 457 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 342 454 9.6E-21 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS06895 ee6ab4a723e8a111c52ee29f26b290cf 457 SMART SM00331 136 453 6.1E-13 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS12550 0ae3ca25af03598137219a4b04232e39 206 SUPERFAMILY SSF109755 42 199 1.83E-5 T 10-11-2016 A4G23_RS12550 0ae3ca25af03598137219a4b04232e39 206 Pfam PF01865 Protein of unknown function DUF47 7 203 3.7E-28 T 10-11-2016 IPR018445 Putative phosphate transport regulator A4G23_RS01660 ade7655886bc327c8420925591c0d5ac 439 Gene3D G3DSA:3.40.190.10 332 380 3.1E-14 T 10-11-2016 A4G23_RS01660 ade7655886bc327c8420925591c0d5ac 439 Gene3D G3DSA:3.40.190.10 4 146 3.1E-14 T 10-11-2016 A4G23_RS01660 ade7655886bc327c8420925591c0d5ac 439 SUPERFAMILY SSF53850 20 433 1.31E-44 T 10-11-2016 A4G23_RS01660 ade7655886bc327c8420925591c0d5ac 439 Gene3D G3DSA:3.40.190.10 153 331 1.6E-20 T 10-11-2016 A4G23_RS01660 ade7655886bc327c8420925591c0d5ac 439 Pfam PF01547 Bacterial extracellular solute-binding protein 60 343 5.8E-27 T 10-11-2016 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 A4G23_RS24170 733e5b019af26b402de32547d1f8d31d 173 Pfam PF01661 Macro domain 20 137 1.5E-37 T 10-11-2016 IPR002589 Macro domain A4G23_RS24170 733e5b019af26b402de32547d1f8d31d 173 SMART SM00506 3 137 1.8E-44 T 10-11-2016 IPR002589 Macro domain A4G23_RS24170 733e5b019af26b402de32547d1f8d31d 173 SUPERFAMILY SSF52949 7 168 9.08E-55 T 10-11-2016 A4G23_RS24170 733e5b019af26b402de32547d1f8d31d 173 Gene3D G3DSA:3.40.220.10 7 169 8.7E-59 T 10-11-2016 A4G23_RS15855 4397f992cdcd7fcb96c9d19372fa99ce 516 SUPERFAMILY SSF53822 97 494 2.59E-17 T 10-11-2016 IPR028082 Periplasmic binding protein-like I A4G23_RS15855 4397f992cdcd7fcb96c9d19372fa99ce 516 Gene3D G3DSA:3.40.50.2300 97 311 1.3E-8 T 10-11-2016 A4G23_RS24635 1975bb3088a2836de5370cbfebb51d7d 318 Gene3D G3DSA:3.20.20.330 5 311 7.3E-87 T 10-11-2016 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 A4G23_RS24635 1975bb3088a2836de5370cbfebb51d7d 318 Pfam PF02574 Homocysteine S-methyltransferase 19 304 4.1E-63 T 10-11-2016 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 A4G23_RS24635 1975bb3088a2836de5370cbfebb51d7d 318 PIRSF PIRSF037505 12 313 9.7E-6 T 10-11-2016 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 Reactome: R-HSA-1614635 A4G23_RS24635 1975bb3088a2836de5370cbfebb51d7d 318 SUPERFAMILY SSF82282 17 309 6.28E-77 T 10-11-2016 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 A4G23_RS27110 cac3c3f69d3864ca25a660d99f02efb8 154 Gene3D G3DSA:2.30.110.10 20 153 4.6E-30 T 10-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 A4G23_RS27110 cac3c3f69d3864ca25a660d99f02efb8 154 SUPERFAMILY SSF50475 21 151 2.03E-14 T 10-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 A4G23_RS27110 cac3c3f69d3864ca25a660d99f02efb8 154 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 26 149 5.3E-25 T 10-11-2016 IPR024747 Pyridoxamine 5'-phosphate oxidase-related A4G23_RS07850 73796da03dbc92c19714ffe691fe4e1f 358 Gene3D G3DSA:3.10.170.10 69 186 2.1E-40 T 10-11-2016 IPR013856 Peptidase M4 domain GO:0004222 A4G23_RS07850 73796da03dbc92c19714ffe691fe4e1f 358 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 185 354 2.7E-52 T 10-11-2016 IPR001570 Peptidase M4, C-terminal GO:0004222 A4G23_RS07850 73796da03dbc92c19714ffe691fe4e1f 358 Gene3D G3DSA:1.10.390.10 187 354 2.8E-53 T 10-11-2016 A4G23_RS07850 73796da03dbc92c19714ffe691fe4e1f 358 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 78 182 5.2E-25 T 10-11-2016 IPR013856 Peptidase M4 domain GO:0004222 A4G23_RS07850 73796da03dbc92c19714ffe691fe4e1f 358 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 173 189 8.8E-28 T 10-11-2016 IPR023612 Peptidase M4 GO:0004222|GO:0006508 A4G23_RS07850 73796da03dbc92c19714ffe691fe4e1f 358 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 194 205 8.8E-28 T 10-11-2016 IPR023612 Peptidase M4 GO:0004222|GO:0006508 A4G23_RS07850 73796da03dbc92c19714ffe691fe4e1f 358 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 275 291 8.8E-28 T 10-11-2016 IPR023612 Peptidase M4 GO:0004222|GO:0006508 A4G23_RS07850 73796da03dbc92c19714ffe691fe4e1f 358 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 137 157 8.8E-28 T 10-11-2016 IPR023612 Peptidase M4 GO:0004222|GO:0006508 A4G23_RS07850 73796da03dbc92c19714ffe691fe4e1f 358 SUPERFAMILY SSF55486 53 354 1.34E-80 T 10-11-2016 A4G23_RS27060 fe00476c643b9f2e007568c9de319ce3 331 Gene3D G3DSA:3.40.50.720 1 226 1.7E-19 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS27060 fe00476c643b9f2e007568c9de319ce3 331 SUPERFAMILY SSF51735 1 306 3.27E-30 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS13135 eab2190ce264ecf9c3c6a7459b7d6870 270 SUPERFAMILY SSF56317 1 254 1.31E-68 T 10-11-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 A4G23_RS13135 eab2190ce264ecf9c3c6a7459b7d6870 270 Gene3D G3DSA:3.60.110.10 1 258 7.5E-76 T 10-11-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 A4G23_RS13135 eab2190ce264ecf9c3c6a7459b7d6870 270 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 141 161 - T 10-11-2016 IPR001110 Uncharacterised protein family UPF0012, conserved site A4G23_RS13135 eab2190ce264ecf9c3c6a7459b7d6870 270 Pfam PF00795 Carbon-nitrogen hydrolase 21 245 1.4E-46 T 10-11-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 A4G23_RS23635 8789d70e3f6d1fc928b17b53b011b1a4 320 SUPERFAMILY SSF55874 194 314 3.01E-15 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS23635 8789d70e3f6d1fc928b17b53b011b1a4 320 SMART SM00387 227 317 2.5E-4 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS23635 8789d70e3f6d1fc928b17b53b011b1a4 320 SMART SM00304 60 112 1.0E-7 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS23635 8789d70e3f6d1fc928b17b53b011b1a4 320 Gene3D G3DSA:3.30.565.10 196 274 9.4E-7 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS23635 8789d70e3f6d1fc928b17b53b011b1a4 320 Pfam PF07730 Histidine kinase 125 189 5.1E-17 T 10-11-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4G23_RS23635 8789d70e3f6d1fc928b17b53b011b1a4 320 Pfam PF00672 HAMP domain 42 109 2.1E-7 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS03440 b94c05075a83b8b44c86eb831d4f5e3d 298 Gene3D G3DSA:3.30.750.24 166 258 2.0E-16 T 10-11-2016 IPR002645 STAS domain A4G23_RS03440 b94c05075a83b8b44c86eb831d4f5e3d 298 Pfam PF01740 STAS domain 174 271 3.3E-11 T 10-11-2016 IPR002645 STAS domain A4G23_RS03440 b94c05075a83b8b44c86eb831d4f5e3d 298 Pfam PF14361 RsbT co-antagonist protein rsbRD N-terminal domain 14 113 3.1E-15 T 10-11-2016 IPR025751 RsbT co-antagonist protein RsbRD, N-terminal domain A4G23_RS03440 b94c05075a83b8b44c86eb831d4f5e3d 298 SUPERFAMILY SSF52091 165 275 3.14E-20 T 10-11-2016 IPR002645 STAS domain A4G23_RS05750 928612889afc08bd407078c90d3f4ddd 319 Pfam PF03707 Bacterial signalling protein N terminal repeat 56 115 1.0E-11 T 10-11-2016 IPR005330 MHYT domain A4G23_RS05750 928612889afc08bd407078c90d3f4ddd 319 Pfam PF03707 Bacterial signalling protein N terminal repeat 120 172 1.2E-18 T 10-11-2016 IPR005330 MHYT domain A4G23_RS22240 41d8a94843317e660d72226e3de2f7f7 667 SUPERFAMILY SSF52540 75 245 7.25E-6 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05420 b6b85c41ff3ece4b6edd780e3885df2a 462 Pfam PF00544 Pectate lyase 170 381 2.4E-51 T 10-11-2016 IPR002022 Pectate lyase/Amb allergen A4G23_RS05420 b6b85c41ff3ece4b6edd780e3885df2a 462 Gene3D G3DSA:2.160.20.10 69 461 2.3E-107 T 10-11-2016 IPR012334 Pectin lyase fold A4G23_RS05420 b6b85c41ff3ece4b6edd780e3885df2a 462 SMART SM00656 148 387 3.8E-45 T 10-11-2016 IPR002022 Pectate lyase/Amb allergen A4G23_RS05420 b6b85c41ff3ece4b6edd780e3885df2a 462 SUPERFAMILY SSF51126 74 139 9.26E-69 T 10-11-2016 IPR011050 Pectin lyase fold/virulence factor A4G23_RS05420 b6b85c41ff3ece4b6edd780e3885df2a 462 SUPERFAMILY SSF51126 171 461 9.26E-69 T 10-11-2016 IPR011050 Pectin lyase fold/virulence factor A4G23_RS00085 67b76743aa2fccf1946a4cff78e3871a 247 Pfam PF13401 AAA domain 36 156 3.3E-12 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS00085 67b76743aa2fccf1946a4cff78e3871a 247 SUPERFAMILY SSF52540 20 245 6.75E-14 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS00085 67b76743aa2fccf1946a4cff78e3871a 247 Gene3D G3DSA:3.40.50.300 25 138 9.2E-7 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS26830 e054beb0e557773fd834fb98bdba0ed8 423 SMART SM00862 247 313 0.0051 T 10-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4G23_RS26830 e054beb0e557773fd834fb98bdba0ed8 423 Gene3D G3DSA:1.10.10.10 240 303 2.0E-4 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS26830 e054beb0e557773fd834fb98bdba0ed8 423 Pfam PF01590 GAF domain 101 214 4.7E-7 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS02490 0b0fdc05b2738b3d1bd4744831fe5d3f 242 SUPERFAMILY SSF52317 20 214 3.32E-20 T 10-11-2016 IPR029062 Class I glutamine amidotransferase-like A4G23_RS02490 0b0fdc05b2738b3d1bd4744831fe5d3f 242 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 9 202 6.4E-36 T 10-11-2016 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 A4G23_RS02490 0b0fdc05b2738b3d1bd4744831fe5d3f 242 Gene3D G3DSA:3.40.50.880 22 213 3.2E-19 T 10-11-2016 IPR029062 Class I glutamine amidotransferase-like A4G23_RS25310 22a5d0b09b24dfb0a30d34e92b770f8f 521 SUPERFAMILY SSF54373 383 454 4.32E-5 T 10-11-2016 A4G23_RS25310 22a5d0b09b24dfb0a30d34e92b770f8f 521 Gene3D G3DSA:3.50.50.60 414 512 4.3E-63 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS25310 22a5d0b09b24dfb0a30d34e92b770f8f 521 Gene3D G3DSA:3.50.50.60 202 309 4.3E-63 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS25310 22a5d0b09b24dfb0a30d34e92b770f8f 521 Gene3D G3DSA:3.50.50.60 15 139 4.3E-63 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS25310 22a5d0b09b24dfb0a30d34e92b770f8f 521 Pfam PF05199 GMC oxidoreductase 385 504 5.1E-24 T 10-11-2016 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 A4G23_RS25310 22a5d0b09b24dfb0a30d34e92b770f8f 521 Pfam PF00732 GMC oxidoreductase 19 305 4.2E-14 T 10-11-2016 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 A4G23_RS25310 22a5d0b09b24dfb0a30d34e92b770f8f 521 SUPERFAMILY SSF51905 450 513 3.58E-51 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS25310 22a5d0b09b24dfb0a30d34e92b770f8f 521 SUPERFAMILY SSF51905 16 307 3.58E-51 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS05020 e1f906a6c4e1517f0f65d901edc5d307 89 SUPERFAMILY SSF50486 9 80 2.04E-12 T 10-11-2016 IPR011034 Formyl transferase, C-terminal-like GO:0003824 A4G23_RS05020 e1f906a6c4e1517f0f65d901edc5d307 89 Gene3D G3DSA:3.10.300.10 9 79 2.5E-14 T 10-11-2016 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 A4G23_RS05020 e1f906a6c4e1517f0f65d901edc5d307 89 Pfam PF02245 Methylpurine-DNA glycosylase (MPG) 14 80 1.2E-13 T 10-11-2016 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 A4G23_RS02610 4daf564d0d14a1f63824af0e94c9e2a4 142 SUPERFAMILY SSF55729 2 134 8.81E-26 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS02610 4daf564d0d14a1f63824af0e94c9e2a4 142 Gene3D G3DSA:3.40.630.30 4 135 9.0E-27 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS02610 4daf564d0d14a1f63824af0e94c9e2a4 142 Pfam PF00583 Acetyltransferase (GNAT) family 58 127 3.3E-13 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS04225 041df2994a0f0d42678a0a5484dc62e9 223 Pfam PF13411 MerR HTH family regulatory protein 2 69 1.4E-17 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS04225 041df2994a0f0d42678a0a5484dc62e9 223 Gene3D G3DSA:1.10.1660.10 2 94 6.0E-21 T 10-11-2016 A4G23_RS04225 041df2994a0f0d42678a0a5484dc62e9 223 SMART SM00422 1 71 3.3E-10 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS04225 041df2994a0f0d42678a0a5484dc62e9 223 SUPERFAMILY SSF46955 2 93 2.6E-17 T 10-11-2016 IPR009061 Putative DNA-binding domain A4G23_RS04225 041df2994a0f0d42678a0a5484dc62e9 223 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 3.4E-11 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS04225 041df2994a0f0d42678a0a5484dc62e9 223 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 3.4E-11 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS04225 041df2994a0f0d42678a0a5484dc62e9 223 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 3.4E-11 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS16065 a99c51f89889c6bbdbeeed2826353834 280 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 22 164 3.7E-50 T 10-11-2016 A4G23_RS16065 a99c51f89889c6bbdbeeed2826353834 280 TIGRFAM TIGR01958 nuoE_fam: NADH-quinone oxidoreductase, E subunit 22 164 6.8E-44 T 10-11-2016 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16065 a99c51f89889c6bbdbeeed2826353834 280 ProSitePatterns PS01099 Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. 122 140 - T 10-11-2016 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16065 a99c51f89889c6bbdbeeed2826353834 280 SUPERFAMILY SSF52833 17 174 4.03E-49 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS16065 a99c51f89889c6bbdbeeed2826353834 280 Gene3D G3DSA:3.40.30.10 85 171 5.3E-11 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS22745 4194da5500d0f010251cbd761a57f13a 750 Gene3D G3DSA:1.10.510.10 126 220 3.3E-8 T 10-11-2016 A4G23_RS22745 4194da5500d0f010251cbd761a57f13a 750 SUPERFAMILY SSF52540 469 494 3.1E-11 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS22745 4194da5500d0f010251cbd761a57f13a 750 SUPERFAMILY SSF52540 524 652 3.1E-11 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS22745 4194da5500d0f010251cbd761a57f13a 750 Gene3D G3DSA:3.40.50.300 530 651 2.1E-6 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS22745 4194da5500d0f010251cbd761a57f13a 750 Gene3D G3DSA:3.40.50.300 470 493 2.1E-6 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS22745 4194da5500d0f010251cbd761a57f13a 750 SUPERFAMILY SSF56112 93 224 4.1E-11 T 10-11-2016 IPR011009 Protein kinase-like domain A4G23_RS11885 67979ed1d97cbde394d62540d2539f24 276 Gene3D G3DSA:3.40.190.10 73 175 1.7E-14 T 10-11-2016 A4G23_RS11885 67979ed1d97cbde394d62540d2539f24 276 Pfam PF02621 Menaquinone biosynthesis 1 260 2.5E-87 T 10-11-2016 IPR003773 Menaquinone biosynthesis enzyme A4G23_RS11885 67979ed1d97cbde394d62540d2539f24 276 SUPERFAMILY SSF53850 1 265 1.29E-81 T 10-11-2016 A4G23_RS11885 67979ed1d97cbde394d62540d2539f24 276 Hamap MF_00996 1,4-dihydroxy-6-naphtoate synthase [mqnD]. 1 266 37.086 T 10-11-2016 IPR030869 1,4-dihydroxy-6-naphtoate synthase GO:0009234|GO:0016829 A4G23_RS06800 fd7823497e54e74ff0aa2b9e3d8bb261 331 SUPERFAMILY SSF51735 1 299 7.81E-31 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS06800 fd7823497e54e74ff0aa2b9e3d8bb261 331 Gene3D G3DSA:3.40.50.720 1 299 2.1E-15 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS06585 fc73f860b67ff26a7f32e34f80923cc1 324 Pfam PF00294 pfkB family carbohydrate kinase 32 295 1.4E-37 T 10-11-2016 IPR011611 Carbohydrate kinase PfkB A4G23_RS06585 fc73f860b67ff26a7f32e34f80923cc1 324 SUPERFAMILY SSF53613 2 296 1.22E-53 T 10-11-2016 IPR029056 Ribokinase-like A4G23_RS06585 fc73f860b67ff26a7f32e34f80923cc1 324 Gene3D G3DSA:3.40.1190.20 2 309 6.3E-46 T 10-11-2016 IPR029056 Ribokinase-like A4G23_RS06585 fc73f860b67ff26a7f32e34f80923cc1 324 PRINTS PR00990 Ribokinase signature 184 199 7.7E-5 T 10-11-2016 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 A4G23_RS06585 fc73f860b67ff26a7f32e34f80923cc1 324 PRINTS PR00990 Ribokinase signature 42 61 7.7E-5 T 10-11-2016 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 A4G23_RS06585 fc73f860b67ff26a7f32e34f80923cc1 324 PRINTS PR00990 Ribokinase signature 220 231 7.7E-5 T 10-11-2016 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 A4G23_RS20395 ba32a01b674dabb59520a686477edc1e 194 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 119 125 - T 10-11-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A4G23_RS20395 ba32a01b674dabb59520a686477edc1e 194 Pfam PF03602 Conserved hypothetical protein 95 2 183 2.2E-50 T 10-11-2016 A4G23_RS20395 ba32a01b674dabb59520a686477edc1e 194 PIRSF PIRSF004553 1 187 1.0E-48 T 10-11-2016 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A4G23_RS20395 ba32a01b674dabb59520a686477edc1e 194 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 2 183 4.8E-42 T 10-11-2016 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A4G23_RS20395 ba32a01b674dabb59520a686477edc1e 194 SUPERFAMILY SSF53335 2 182 5.35E-42 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS20395 ba32a01b674dabb59520a686477edc1e 194 Gene3D G3DSA:3.40.50.150 1 186 3.4E-56 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS19995 1ca74d04223117848d5a01fd7ac48554 333 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 319 3.7E-19 T 10-11-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A4G23_RS19995 1ca74d04223117848d5a01fd7ac48554 333 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 299 7.4E-14 T 10-11-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A4G23_RS19995 1ca74d04223117848d5a01fd7ac48554 333 Gene3D G3DSA:3.40.50.300 2 256 4.0E-70 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS19995 1ca74d04223117848d5a01fd7ac48554 333 SUPERFAMILY SSF52540 33 305 2.13E-62 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS19995 1ca74d04223117848d5a01fd7ac48554 333 Pfam PF00005 ABC transporter 25 182 3.5E-25 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS19995 1ca74d04223117848d5a01fd7ac48554 333 SMART SM00382 33 231 4.7E-15 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS19995 1ca74d04223117848d5a01fd7ac48554 333 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS02505 ed53fb0ded3bf2492872214bd192d5ea 276 SUPERFAMILY SSF51126 60 234 1.88E-54 T 10-11-2016 IPR011050 Pectin lyase fold/virulence factor A4G23_RS02505 ed53fb0ded3bf2492872214bd192d5ea 276 Pfam PF03211 Pectate lyase 48 250 9.2E-80 T 10-11-2016 IPR004898 Pectate lyase, catalytic GO:0005576|GO:0030570 KEGG: 00040+4.2.2.2 A4G23_RS02505 ed53fb0ded3bf2492872214bd192d5ea 276 Gene3D G3DSA:2.160.20.10 60 275 1.3E-86 T 10-11-2016 IPR012334 Pectin lyase fold A4G23_RS20240 1304bec113ae880f6ec67ecef4380db0 137 Pfam PF03259 Roadblock/LC7 domain 9 99 5.5E-25 T 10-11-2016 IPR004942 Roadblock/LAMTOR2 domain A4G23_RS20240 1304bec113ae880f6ec67ecef4380db0 137 SUPERFAMILY SSF103196 2 125 9.42E-32 T 10-11-2016 A4G23_RS20240 1304bec113ae880f6ec67ecef4380db0 137 SMART SM00960 9 99 1.5E-31 T 10-11-2016 IPR004942 Roadblock/LAMTOR2 domain A4G23_RS20240 1304bec113ae880f6ec67ecef4380db0 137 Gene3D G3DSA:3.30.450.30 3 123 4.7E-25 T 10-11-2016 A4G23_RS14395 c5fff34e0c9265cf920ec75eee5bb569 165 Gene3D G3DSA:3.40.50.2020 9 153 2.6E-33 T 10-11-2016 IPR029057 Phosphoribosyltransferase-like A4G23_RS14395 c5fff34e0c9265cf920ec75eee5bb569 165 SUPERFAMILY SSF53271 8 153 3.02E-27 T 10-11-2016 IPR029057 Phosphoribosyltransferase-like A4G23_RS14395 c5fff34e0c9265cf920ec75eee5bb569 165 Pfam PF00156 Phosphoribosyl transferase domain 14 152 4.4E-25 T 10-11-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 A4G23_RS20315 064cac9d63b23f17391862e4d94f6085 238 Gene3D G3DSA:3.30.450.40 74 228 2.9E-39 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS20315 064cac9d63b23f17391862e4d94f6085 238 SUPERFAMILY SSF46785 7 75 8.95E-11 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS20315 064cac9d63b23f17391862e4d94f6085 238 SUPERFAMILY SSF55781 62 234 9.16E-34 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS20315 064cac9d63b23f17391862e4d94f6085 238 Pfam PF09339 IclR helix-turn-helix domain 10 57 1.5E-9 T 10-11-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4G23_RS20315 064cac9d63b23f17391862e4d94f6085 238 SMART SM00346 7 93 9.5E-15 T 10-11-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4G23_RS20315 064cac9d63b23f17391862e4d94f6085 238 Gene3D G3DSA:1.10.10.10 3 73 1.6E-16 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS20315 064cac9d63b23f17391862e4d94f6085 238 Pfam PF01614 Bacterial transcriptional regulator 125 231 1.4E-15 T 10-11-2016 IPR014757 Transcription regulator IclR, C-terminal A4G23_RS11030 f6ae2c8a87e4ce34da5e12c4f7cd6fd6 358 Pfam PF03235 Protein of unknown function DUF262 37 190 5.2E-30 T 10-11-2016 IPR004919 Domain of unknown function DUF262 A4G23_RS00245 e5280c52a1d58823951d91b10b7b398f 157 Pfam PF13581 Histidine kinase-like ATPase domain 38 139 1.3E-6 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS00245 e5280c52a1d58823951d91b10b7b398f 157 Gene3D G3DSA:3.30.565.10 50 103 4.9E-5 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS00245 e5280c52a1d58823951d91b10b7b398f 157 SUPERFAMILY SSF55874 44 104 2.17E-7 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS23125 5b03091fbb00db584a3d2072605dcf08 317 Gene3D G3DSA:3.80.10.10 33 299 3.2E-60 T 10-11-2016 IPR032675 Leucine-rich repeat domain, L domain-like A4G23_RS23125 5b03091fbb00db584a3d2072605dcf08 317 SUPERFAMILY SSF52047 149 285 1.52E-10 T 10-11-2016 A4G23_RS05245 8207d2764e68ea7733e16de113b53ac6 266 Pfam PF00378 Enoyl-CoA hydratase/isomerase 21 253 6.4E-40 T 10-11-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 A4G23_RS05245 8207d2764e68ea7733e16de113b53ac6 266 SUPERFAMILY SSF52096 13 258 6.84E-63 T 10-11-2016 IPR029045 ClpP/crotonase-like domain A4G23_RS05245 8207d2764e68ea7733e16de113b53ac6 266 Gene3D G3DSA:3.90.226.10 14 259 1.4E-60 T 10-11-2016 IPR029045 ClpP/crotonase-like domain A4G23_RS05245 8207d2764e68ea7733e16de113b53ac6 266 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 122 142 - T 10-11-2016 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 A4G23_RS04965 c8d4ff50a60cfd1f81452fe0d3c76e93 273 Gene3D G3DSA:3.40.50.300 12 246 2.2E-62 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS04965 c8d4ff50a60cfd1f81452fe0d3c76e93 273 SMART SM00382 34 223 3.4E-15 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS04965 c8d4ff50a60cfd1f81452fe0d3c76e93 273 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS04965 c8d4ff50a60cfd1f81452fe0d3c76e93 273 SUPERFAMILY SSF52540 10 235 3.04E-59 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS04965 c8d4ff50a60cfd1f81452fe0d3c76e93 273 Pfam PF00005 ABC transporter 27 173 4.4E-29 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS26435 75e4c1d93c9296ae8e07fb2cef348a55 246 Pfam PF03704 Bacterial transcriptional activator domain 99 226 1.6E-23 T 10-11-2016 IPR005158 Bacterial transcriptional activator domain A4G23_RS26435 75e4c1d93c9296ae8e07fb2cef348a55 246 SMART SM01043 90 230 1.3E-26 T 10-11-2016 IPR005158 Bacterial transcriptional activator domain A4G23_RS26435 75e4c1d93c9296ae8e07fb2cef348a55 246 SUPERFAMILY SSF48452 91 228 4.84E-19 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS20275 b0cd825866f3e37ce909800aa5c11199 262 SUPERFAMILY SSF56529 55 259 6.15E-80 T 10-11-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 A4G23_RS20275 b0cd825866f3e37ce909800aa5c11199 262 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 64 258 1.5E-69 T 10-11-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 A4G23_RS20275 b0cd825866f3e37ce909800aa5c11199 262 Gene3D G3DSA:3.90.850.10 55 260 2.2E-92 T 10-11-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 A4G23_RS20275 b0cd825866f3e37ce909800aa5c11199 262 Pfam PF10370 Domain of unknown function (DUF2437) 2 59 5.8E-10 T 10-11-2016 IPR018833 Domain of unknown function DUF2437 A4G23_RS06605 3e257b25cc51db48476efc76c3ff3401 392 SUPERFAMILY SSF142754 50 391 9.94E-94 T 10-11-2016 A4G23_RS06605 3e257b25cc51db48476efc76c3ff3401 392 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 46 391 6.1E-98 T 10-11-2016 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 A4G23_RS06605 3e257b25cc51db48476efc76c3ff3401 392 Pfam PF02445 Quinolinate synthetase A protein 52 390 2.5E-106 T 10-11-2016 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 A4G23_RS06605 3e257b25cc51db48476efc76c3ff3401 392 Hamap MF_00569 Quinolinate synthase A [nadA]. 41 391 56.995 T 10-11-2016 IPR023515 Quinolinate synthase A, type 3 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 A4G23_RS26655 34bf47093e7fa344c1458fc098ca1d27 462 Gene3D G3DSA:1.20.1440.30 186 319 2.7E-36 T 10-11-2016 A4G23_RS26655 34bf47093e7fa344c1458fc098ca1d27 462 Gene3D G3DSA:3.30.1870.10 107 181 1.3E-20 T 10-11-2016 A4G23_RS26655 34bf47093e7fa344c1458fc098ca1d27 462 PIRSF PIRSF036794 31 462 2.8E-127 T 10-11-2016 IPR014622 Uncharacterised conserved protein UCP036794, erythromycin esterase-type A4G23_RS26655 34bf47093e7fa344c1458fc098ca1d27 462 SUPERFAMILY SSF159501 42 458 1.15E-105 T 10-11-2016 A4G23_RS26655 34bf47093e7fa344c1458fc098ca1d27 462 Pfam PF05139 Erythromycin esterase 105 452 1.2E-75 T 10-11-2016 IPR007815 Erythromycin esterase GO:0046677 A4G23_RS26655 34bf47093e7fa344c1458fc098ca1d27 462 Gene3D G3DSA:3.40.1660.10 43 106 2.3E-52 T 10-11-2016 A4G23_RS26655 34bf47093e7fa344c1458fc098ca1d27 462 Gene3D G3DSA:3.40.1660.10 321 458 2.3E-52 T 10-11-2016 A4G23_RS18015 677ae681d0b0006b6a53d5a7af5a2369 231 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 72 83 1.9E-9 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS18015 677ae681d0b0006b6a53d5a7af5a2369 231 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 1.9E-9 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS18015 677ae681d0b0006b6a53d5a7af5a2369 231 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 126 134 1.9E-9 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS18015 677ae681d0b0006b6a53d5a7af5a2369 231 Gene3D G3DSA:3.40.50.720 1 229 2.8E-59 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS18015 677ae681d0b0006b6a53d5a7af5a2369 231 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 10-11-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4G23_RS18015 677ae681d0b0006b6a53d5a7af5a2369 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 3.4E-21 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS18015 677ae681d0b0006b6a53d5a7af5a2369 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 3.4E-21 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS18015 677ae681d0b0006b6a53d5a7af5a2369 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 3.4E-21 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS18015 677ae681d0b0006b6a53d5a7af5a2369 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 3.4E-21 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS18015 677ae681d0b0006b6a53d5a7af5a2369 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 3.4E-21 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS18015 677ae681d0b0006b6a53d5a7af5a2369 231 Pfam PF00106 short chain dehydrogenase 4 195 9.8E-39 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS18015 677ae681d0b0006b6a53d5a7af5a2369 231 SUPERFAMILY SSF51735 3 229 1.61E-49 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS06295 074c9b8bdac1370ea5c90bcee9548869 477 Pfam PF01882 Protein of unknown function DUF58 218 296 2.6E-22 T 10-11-2016 IPR002881 Domain of unknown function DUF58 A4G23_RS11430 55b204a9ec3ef351464b825bd1b5725d 194 Pfam PF04542 Sigma-70 region 2 28 96 1.1E-8 T 10-11-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS11430 55b204a9ec3ef351464b825bd1b5725d 194 Gene3D G3DSA:1.10.1740.10 9 113 1.6E-15 T 10-11-2016 A4G23_RS11430 55b204a9ec3ef351464b825bd1b5725d 194 SUPERFAMILY SSF88946 10 99 3.3E-13 T 10-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS11430 55b204a9ec3ef351464b825bd1b5725d 194 SUPERFAMILY SSF88659 122 175 1.83E-5 T 10-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS11430 55b204a9ec3ef351464b825bd1b5725d 194 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 24 174 2.3E-13 T 10-11-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS11430 55b204a9ec3ef351464b825bd1b5725d 194 Gene3D G3DSA:1.10.10.10 128 175 1.7E-4 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS11510 71cd14a5adb6df73b9eee4c05cd56562 367 Gene3D G3DSA:1.10.580.10 13 221 6.5E-48 T 10-11-2016 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 A4G23_RS11510 71cd14a5adb6df73b9eee4c05cd56562 367 PRINTS PR00143 Citrate synthase signature 182 210 2.7E-26 T 10-11-2016 IPR002020 Citrate synthase GO:0046912 A4G23_RS11510 71cd14a5adb6df73b9eee4c05cd56562 367 PRINTS PR00143 Citrate synthase signature 235 255 2.7E-26 T 10-11-2016 IPR002020 Citrate synthase GO:0046912 A4G23_RS11510 71cd14a5adb6df73b9eee4c05cd56562 367 PRINTS PR00143 Citrate synthase signature 294 310 2.7E-26 T 10-11-2016 IPR002020 Citrate synthase GO:0046912 A4G23_RS11510 71cd14a5adb6df73b9eee4c05cd56562 367 PRINTS PR00143 Citrate synthase signature 160 175 2.7E-26 T 10-11-2016 IPR002020 Citrate synthase GO:0046912 A4G23_RS11510 71cd14a5adb6df73b9eee4c05cd56562 367 PRINTS PR00143 Citrate synthase signature 314 328 2.7E-26 T 10-11-2016 IPR002020 Citrate synthase GO:0046912 A4G23_RS11510 71cd14a5adb6df73b9eee4c05cd56562 367 ProSitePatterns PS00480 Citrate synthase signature. 242 254 - T 10-11-2016 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 A4G23_RS11510 71cd14a5adb6df73b9eee4c05cd56562 367 SUPERFAMILY SSF48256 3 355 1.09E-96 T 10-11-2016 IPR002020 Citrate synthase GO:0046912 A4G23_RS11510 71cd14a5adb6df73b9eee4c05cd56562 367 Gene3D G3DSA:1.10.230.10 222 306 2.2E-25 T 10-11-2016 IPR016143 Citrate synthase-like, small alpha subdomain Reactome: R-HSA-163765|Reactome: R-HSA-75105 A4G23_RS11510 71cd14a5adb6df73b9eee4c05cd56562 367 Pfam PF00285 Citrate synthase, C-terminal domain 7 343 1.4E-86 T 10-11-2016 IPR002020 Citrate synthase GO:0046912 A4G23_RS16185 e610291f85f89ea43869a284d68da523 130 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 11 130 16.465 T 10-11-2016 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 A4G23_RS16185 e610291f85f89ea43869a284d68da523 130 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 30 129 4.7E-30 T 10-11-2016 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS20540 8148043c1f62fe43f81930ad8dec0d94 240 Pfam PF00717 Peptidase S24-like 45 114 4.1E-13 T 10-11-2016 IPR019759 Peptidase S24/S26A/S26B A4G23_RS20540 8148043c1f62fe43f81930ad8dec0d94 240 SUPERFAMILY SSF51306 40 192 4.97E-37 T 10-11-2016 IPR015927 Peptidase S24/S26A/S26B/S26C A4G23_RS20540 8148043c1f62fe43f81930ad8dec0d94 240 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 26 188 6.2E-36 T 10-11-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A4G23_RS20540 8148043c1f62fe43f81930ad8dec0d94 240 Gene3D G3DSA:2.10.109.10 142 192 3.1E-28 T 10-11-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain A4G23_RS20540 8148043c1f62fe43f81930ad8dec0d94 240 Gene3D G3DSA:2.10.109.10 39 99 3.1E-28 T 10-11-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain A4G23_RS20540 8148043c1f62fe43f81930ad8dec0d94 240 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 142 161 8.0E-19 T 10-11-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A4G23_RS20540 8148043c1f62fe43f81930ad8dec0d94 240 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 89 101 8.0E-19 T 10-11-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A4G23_RS20540 8148043c1f62fe43f81930ad8dec0d94 240 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 39 55 8.0E-19 T 10-11-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A4G23_RS21105 c509f9621160a779f2a0d3bb8c988fd7 156 Gene3D G3DSA:1.20.1260.10 3 153 3.5E-43 T 10-11-2016 IPR012347 Ferritin-related A4G23_RS21105 c509f9621160a779f2a0d3bb8c988fd7 156 Pfam PF00210 Ferritin-like domain 18 153 1.8E-20 T 10-11-2016 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 A4G23_RS21105 c509f9621160a779f2a0d3bb8c988fd7 156 PIRSF PIRSF005900 1 156 1.2E-41 T 10-11-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 A4G23_RS21105 c509f9621160a779f2a0d3bb8c988fd7 156 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 62 78 4.4E-11 T 10-11-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 A4G23_RS21105 c509f9621160a779f2a0d3bb8c988fd7 156 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 38 54 4.4E-11 T 10-11-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 A4G23_RS21105 c509f9621160a779f2a0d3bb8c988fd7 156 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 133 151 4.4E-11 T 10-11-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 A4G23_RS21105 c509f9621160a779f2a0d3bb8c988fd7 156 SUPERFAMILY SSF47240 3 153 4.96E-44 T 10-11-2016 IPR009078 Ferritin-like superfamily A4G23_RS14910 66d6e0e330876980b5355a5987403a97 383 TIGRFAM TIGR03819 heli_sec_ATPase: helicase/secretion neighborhood ATPase 5 343 2.5E-156 T 10-11-2016 IPR022399 Helicase/secretion neighbourhood ATPase A4G23_RS14910 66d6e0e330876980b5355a5987403a97 383 Pfam PF00437 Type II/IV secretion system protein 56 331 1.4E-79 T 10-11-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 A4G23_RS14910 66d6e0e330876980b5355a5987403a97 383 SUPERFAMILY SSF52540 38 337 1.07E-48 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS14910 66d6e0e330876980b5355a5987403a97 383 Gene3D G3DSA:3.30.450.90 53 148 4.6E-26 T 10-11-2016 A4G23_RS14910 66d6e0e330876980b5355a5987403a97 383 Gene3D G3DSA:3.40.50.300 155 370 2.8E-51 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS19790 09fc6573b9ba2937d0469e0cec436518 341 Pfam PF00365 Phosphofructokinase 2 297 1.7E-101 T 10-11-2016 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A4G23_RS19790 09fc6573b9ba2937d0469e0cec436518 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 2.8E-74 T 10-11-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A4G23_RS19790 09fc6573b9ba2937d0469e0cec436518 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 5 24 2.8E-74 T 10-11-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A4G23_RS19790 09fc6573b9ba2937d0469e0cec436518 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 120 137 2.8E-74 T 10-11-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A4G23_RS19790 09fc6573b9ba2937d0469e0cec436518 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 2.8E-74 T 10-11-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A4G23_RS19790 09fc6573b9ba2937d0469e0cec436518 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 158 174 2.8E-74 T 10-11-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A4G23_RS19790 09fc6573b9ba2937d0469e0cec436518 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 212 224 2.8E-74 T 10-11-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A4G23_RS19790 09fc6573b9ba2937d0469e0cec436518 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 262 284 2.8E-74 T 10-11-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A4G23_RS19790 09fc6573b9ba2937d0469e0cec436518 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 176 193 2.8E-74 T 10-11-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A4G23_RS19790 09fc6573b9ba2937d0469e0cec436518 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 138 156 2.8E-74 T 10-11-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A4G23_RS19790 09fc6573b9ba2937d0469e0cec436518 341 TIGRFAM TIGR02483 PFK_mixed: phosphofructokinase 2 322 8.2E-143 T 10-11-2016 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 A4G23_RS19790 09fc6573b9ba2937d0469e0cec436518 341 Gene3D G3DSA:3.40.50.450 1 213 9.9E-74 T 10-11-2016 A4G23_RS19790 09fc6573b9ba2937d0469e0cec436518 341 ProSitePatterns PS00433 Phosphofructokinase signature. 266 284 - T 10-11-2016 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A4G23_RS19790 09fc6573b9ba2937d0469e0cec436518 341 Hamap MF_01976 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 1 341 42.706 T 10-11-2016 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 A4G23_RS19790 09fc6573b9ba2937d0469e0cec436518 341 SUPERFAMILY SSF53784 1 332 9.94E-121 T 10-11-2016 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A4G23_RS19790 09fc6573b9ba2937d0469e0cec436518 341 PIRSF PIRSF000532 1 340 1.2E-115 T 10-11-2016 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 A4G23_RS07400 2c23df12bf6722cdea3e457e8b858cc8 191 Pfam PF02342 TerD domain 1 186 1.7E-81 T 10-11-2016 IPR003325 TerD domain GO:0006950 A4G23_RS07400 2c23df12bf6722cdea3e457e8b858cc8 191 Gene3D G3DSA:2.60.60.30 18 183 3.0E-72 T 10-11-2016 A4G23_RS13640 1eb693329fad5220d0c33d6383504017 159 SUPERFAMILY SSF55811 4 112 5.82E-20 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS13640 1eb693329fad5220d0c33d6383504017 159 Pfam PF00293 NUDIX domain 9 111 6.5E-13 T 10-11-2016 IPR000086 NUDIX hydrolase domain GO:0016787 A4G23_RS13640 1eb693329fad5220d0c33d6383504017 159 Gene3D G3DSA:3.90.79.10 2 112 3.9E-19 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS21840 c2d0ca04843c3d70f4730a65390b4bbe 195 SUPERFAMILY SSF55874 68 171 5.07E-8 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS21840 c2d0ca04843c3d70f4730a65390b4bbe 195 Gene3D G3DSA:3.30.565.10 61 127 1.9E-4 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS21840 c2d0ca04843c3d70f4730a65390b4bbe 195 Pfam PF13581 Histidine kinase-like ATPase domain 52 164 3.7E-11 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS20415 5d7962f25304a4521f1b448414f3b6e2 57 SUPERFAMILY SSF57829 2 55 1.71E-20 T 10-11-2016 IPR011332 Zinc-binding ribosomal protein GO:0006412 A4G23_RS20415 5d7962f25304a4521f1b448414f3b6e2 57 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 55 3.6E-25 T 10-11-2016 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS20415 5d7962f25304a4521f1b448414f3b6e2 57 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 2 55 18.826 T 10-11-2016 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS20415 5d7962f25304a4521f1b448414f3b6e2 57 Pfam PF01783 Ribosomal L32p protein family 2 56 8.0E-25 T 10-11-2016 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS21940 7f6716dffec630f8744390dc367c120c 600 PRINTS PR01036 Tetracycline resistance protein TetB signature 104 126 5.8E-10 T 10-11-2016 A4G23_RS21940 7f6716dffec630f8744390dc367c120c 600 PRINTS PR01036 Tetracycline resistance protein TetB signature 44 68 5.8E-10 T 10-11-2016 A4G23_RS21940 7f6716dffec630f8744390dc367c120c 600 PRINTS PR01036 Tetracycline resistance protein TetB signature 166 190 5.8E-10 T 10-11-2016 A4G23_RS21940 7f6716dffec630f8744390dc367c120c 600 PRINTS PR01036 Tetracycline resistance protein TetB signature 191 215 5.8E-10 T 10-11-2016 A4G23_RS21940 7f6716dffec630f8744390dc367c120c 600 PRINTS PR01036 Tetracycline resistance protein TetB signature 407 426 5.8E-10 T 10-11-2016 A4G23_RS21940 7f6716dffec630f8744390dc367c120c 600 PRINTS PR01036 Tetracycline resistance protein TetB signature 136 156 5.8E-10 T 10-11-2016 A4G23_RS21940 7f6716dffec630f8744390dc367c120c 600 Gene3D G3DSA:1.20.1250.20 40 216 1.3E-21 T 10-11-2016 A4G23_RS21940 7f6716dffec630f8744390dc367c120c 600 Pfam PF07690 Major Facilitator Superfamily 47 467 2.9E-44 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS21940 7f6716dffec630f8744390dc367c120c 600 SUPERFAMILY SSF103473 39 231 6.15E-46 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS21940 7f6716dffec630f8744390dc367c120c 600 SUPERFAMILY SSF103473 301 477 6.15E-46 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS21940 7f6716dffec630f8744390dc367c120c 600 SUPERFAMILY SSF103473 544 571 6.15E-46 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS21940 7f6716dffec630f8744390dc367c120c 600 Gene3D G3DSA:1.20.1250.20 313 478 4.0E-12 T 10-11-2016 A4G23_RS11915 3cf0cd87dc2868feb67fb19eb2411089 60 SUPERFAMILY SSF47598 6 39 4.2E-7 T 10-11-2016 IPR010985 Ribbon-helix-helix GO:0006355 A4G23_RS20580 d3aa414e486f34e5f09e000f90356e48 141 SUPERFAMILY SSF51261 17 129 3.45E-16 T 10-11-2016 IPR011055 Duplicated hybrid motif A4G23_RS20580 d3aa414e486f34e5f09e000f90356e48 141 Gene3D G3DSA:2.70.70.10 2 130 8.7E-23 T 10-11-2016 A4G23_RS20580 d3aa414e486f34e5f09e000f90356e48 141 Pfam PF01551 Peptidase family M23 26 125 1.5E-13 T 10-11-2016 IPR016047 Peptidase M23 A4G23_RS21545 415622a6021393b59604e2b6ddaad564 227 SMART SM00448 2 112 2.3E-40 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS21545 415622a6021393b59604e2b6ddaad564 227 Pfam PF00072 Response regulator receiver domain 4 112 6.6E-28 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS21545 415622a6021393b59604e2b6ddaad564 227 Gene3D G3DSA:1.10.10.10 130 226 1.4E-29 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS21545 415622a6021393b59604e2b6ddaad564 227 Gene3D G3DSA:3.40.50.2300 1 121 1.6E-38 T 10-11-2016 A4G23_RS21545 415622a6021393b59604e2b6ddaad564 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 225 3.8E-23 T 10-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4G23_RS21545 415622a6021393b59604e2b6ddaad564 227 SMART SM00862 149 225 3.5E-23 T 10-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4G23_RS21545 415622a6021393b59604e2b6ddaad564 227 SUPERFAMILY SSF52172 1 181 1.57E-39 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS13735 9a0eaaed3e7fab2538f54b1fd903b159 301 Pfam PF00296 Luciferase-like monooxygenase 22 237 3.4E-44 T 10-11-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4G23_RS13735 9a0eaaed3e7fab2538f54b1fd903b159 301 SUPERFAMILY SSF51679 15 285 1.27E-53 T 10-11-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4G23_RS13735 9a0eaaed3e7fab2538f54b1fd903b159 301 Gene3D G3DSA:3.20.20.30 2 237 6.4E-59 T 10-11-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4G23_RS27300 9886c10009f97598aa253f81267c8bfb 395 Gene3D G3DSA:3.30.870.10 235 370 1.7E-29 T 10-11-2016 A4G23_RS27300 9886c10009f97598aa253f81267c8bfb 395 SUPERFAMILY SSF56024 211 378 2.92E-34 T 10-11-2016 A4G23_RS27300 9886c10009f97598aa253f81267c8bfb 395 SUPERFAMILY SSF56024 29 219 9.1E-43 T 10-11-2016 A4G23_RS27300 9886c10009f97598aa253f81267c8bfb 395 SMART SM00155 131 158 16.0 T 10-11-2016 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 A4G23_RS27300 9886c10009f97598aa253f81267c8bfb 395 SMART SM00155 308 335 0.0034 T 10-11-2016 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 A4G23_RS27300 9886c10009f97598aa253f81267c8bfb 395 Pfam PF13091 PLD-like domain 50 153 1.5E-13 T 10-11-2016 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148 A4G23_RS27300 9886c10009f97598aa253f81267c8bfb 395 Pfam PF13091 PLD-like domain 237 362 1.1E-24 T 10-11-2016 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148 A4G23_RS27300 9886c10009f97598aa253f81267c8bfb 395 Gene3D G3DSA:3.30.870.10 27 220 3.6E-41 T 10-11-2016 A4G23_RS16215 d5d1fd176d615ac8ad8d17e5a0dc233b 149 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 1 102 18.565 T 10-11-2016 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 A4G23_RS16215 d5d1fd176d615ac8ad8d17e5a0dc233b 149 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 8 97 8.6E-27 T 10-11-2016 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 A4G23_RS24405 03347347b99381548a1111d6d8e4524c 451 Gene3D G3DSA:3.50.50.60 175 354 2.2E-28 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS24405 03347347b99381548a1111d6d8e4524c 451 Gene3D G3DSA:3.50.50.60 8 110 2.6E-17 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS24405 03347347b99381548a1111d6d8e4524c 451 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 10 333 1.8E-58 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS24405 03347347b99381548a1111d6d8e4524c 451 Gene3D G3DSA:3.40.50.720 164 174 4.1E-4 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS24405 03347347b99381548a1111d6d8e4524c 451 Gene3D G3DSA:3.40.50.720 111 131 4.1E-4 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS24405 03347347b99381548a1111d6d8e4524c 451 SUPERFAMILY SSF51905 5 342 3.65E-32 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS24405 03347347b99381548a1111d6d8e4524c 451 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 1.4E-5 T 10-11-2016 A4G23_RS24405 03347347b99381548a1111d6d8e4524c 451 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 250 264 1.4E-5 T 10-11-2016 A4G23_RS24405 03347347b99381548a1111d6d8e4524c 451 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 303 310 1.4E-5 T 10-11-2016 A4G23_RS24405 03347347b99381548a1111d6d8e4524c 451 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 167 192 1.4E-5 T 10-11-2016 A4G23_RS24405 03347347b99381548a1111d6d8e4524c 451 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 2.1E-14 T 10-11-2016 A4G23_RS24405 03347347b99381548a1111d6d8e4524c 451 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 167 185 2.1E-14 T 10-11-2016 A4G23_RS24405 03347347b99381548a1111d6d8e4524c 451 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 107 125 2.1E-14 T 10-11-2016 A4G23_RS24405 03347347b99381548a1111d6d8e4524c 451 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 288 310 2.1E-14 T 10-11-2016 A4G23_RS23415 88ef595537e6eb22b2e43633bcfbe772 339 SUPERFAMILY SSF81345 8 334 9.02E-59 T 10-11-2016 IPR029022 ABC transporter, BtuC-like A4G23_RS23415 88ef595537e6eb22b2e43633bcfbe772 339 Gene3D G3DSA:1.10.3470.10 8 336 3.7E-75 T 10-11-2016 IPR029022 ABC transporter, BtuC-like A4G23_RS23415 88ef595537e6eb22b2e43633bcfbe772 339 Pfam PF01032 FecCD transport family 21 334 1.4E-66 T 10-11-2016 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 A4G23_RS24700 5a368c833c4a563609edfde720aa4fb9 68 Pfam PF02467 Transcription factor WhiB 2 59 1.9E-21 T 10-11-2016 IPR003482 Transcription factor WhiB A4G23_RS24700 5a368c833c4a563609edfde720aa4fb9 68 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 64 16.085 T 10-11-2016 IPR003482 Transcription factor WhiB A4G23_RS21080 e59be9a00a70cd179fb81a09a4050e04 282 Pfam PF13413 Helix-turn-helix domain 36 95 5.5E-21 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS21080 e59be9a00a70cd179fb81a09a4050e04 282 Gene3D G3DSA:1.10.260.40 25 101 1.4E-6 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS21080 e59be9a00a70cd179fb81a09a4050e04 282 Pfam PF13464 Domain of unknown function (DUF4115) 201 273 9.5E-17 T 10-11-2016 IPR025194 Domain of unknown function DUF4115 A4G23_RS23875 a86269e5ea45a95a3a7911b55ea56ae9 632 Gene3D G3DSA:1.10.510.10 123 336 9.5E-42 T 10-11-2016 A4G23_RS23875 a86269e5ea45a95a3a7911b55ea56ae9 632 Pfam PF00069 Protein kinase domain 27 271 2.1E-38 T 10-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4G23_RS23875 a86269e5ea45a95a3a7911b55ea56ae9 632 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 144 156 - T 10-11-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 A4G23_RS23875 a86269e5ea45a95a3a7911b55ea56ae9 632 SUPERFAMILY SSF56112 25 359 2.97E-65 T 10-11-2016 IPR011009 Protein kinase-like domain A4G23_RS23875 a86269e5ea45a95a3a7911b55ea56ae9 632 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 32 54 - T 10-11-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 A4G23_RS23875 a86269e5ea45a95a3a7911b55ea56ae9 632 Gene3D G3DSA:3.30.200.20 16 122 1.2E-14 T 10-11-2016 A4G23_RS23875 a86269e5ea45a95a3a7911b55ea56ae9 632 SMART SM00220 26 278 2.0E-43 T 10-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4G23_RS06995 0c658213f7eb22a071d448619c0527ba 224 Pfam PF02567 Phenazine biosynthesis-like protein 21 89 8.2E-11 T 10-11-2016 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 A4G23_RS06995 0c658213f7eb22a071d448619c0527ba 224 Gene3D G3DSA:3.10.310.10 8 119 1.7E-18 T 10-11-2016 A4G23_RS06995 0c658213f7eb22a071d448619c0527ba 224 SUPERFAMILY SSF54506 7 220 1.14E-27 T 10-11-2016 A4G23_RS06995 0c658213f7eb22a071d448619c0527ba 224 Gene3D G3DSA:3.10.310.10 133 192 1.3E-6 T 10-11-2016 A4G23_RS27155 8058f84075b9eae25a5f820219a9877d 397 PRINTS PR00385 P450 superfamily signature 272 283 1.6E-7 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS27155 8058f84075b9eae25a5f820219a9877d 397 PRINTS PR00385 P450 superfamily signature 237 254 1.6E-7 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS27155 8058f84075b9eae25a5f820219a9877d 397 PRINTS PR00385 P450 superfamily signature 340 349 1.6E-7 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS27155 8058f84075b9eae25a5f820219a9877d 397 PRINTS PR00385 P450 superfamily signature 349 360 1.6E-7 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS27155 8058f84075b9eae25a5f820219a9877d 397 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 342 351 - T 10-11-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A4G23_RS27155 8058f84075b9eae25a5f820219a9877d 397 PRINTS PR00359 B-class P450 signature 291 318 7.8E-61 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS27155 8058f84075b9eae25a5f820219a9877d 397 PRINTS PR00359 B-class P450 signature 136 152 7.8E-61 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS27155 8058f84075b9eae25a5f820219a9877d 397 PRINTS PR00359 B-class P450 signature 319 334 7.8E-61 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS27155 8058f84075b9eae25a5f820219a9877d 397 PRINTS PR00359 B-class P450 signature 89 100 7.8E-61 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS27155 8058f84075b9eae25a5f820219a9877d 397 PRINTS PR00359 B-class P450 signature 191 213 7.8E-61 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS27155 8058f84075b9eae25a5f820219a9877d 397 PRINTS PR00359 B-class P450 signature 153 168 7.8E-61 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS27155 8058f84075b9eae25a5f820219a9877d 397 PRINTS PR00359 B-class P450 signature 349 360 7.8E-61 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS27155 8058f84075b9eae25a5f820219a9877d 397 PRINTS PR00359 B-class P450 signature 272 283 7.8E-61 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS27155 8058f84075b9eae25a5f820219a9877d 397 PRINTS PR00359 B-class P450 signature 340 349 7.8E-61 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS27155 8058f84075b9eae25a5f820219a9877d 397 Gene3D G3DSA:1.10.630.10 11 397 5.6E-129 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS27155 8058f84075b9eae25a5f820219a9877d 397 SUPERFAMILY SSF48264 20 397 2.88E-100 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS27155 8058f84075b9eae25a5f820219a9877d 397 Pfam PF00067 Cytochrome P450 177 371 3.4E-23 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS20855 3dc33728accb936a0618423faee48a5a 192 Pfam PF00583 Acetyltransferase (GNAT) family 59 151 3.2E-11 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS20855 3dc33728accb936a0618423faee48a5a 192 Gene3D G3DSA:3.40.630.30 22 172 2.5E-18 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS20855 3dc33728accb936a0618423faee48a5a 192 SUPERFAMILY SSF55729 26 158 6.69E-18 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS12520 27d5b334348717901e09a6b168a0a18f 127 Gene3D G3DSA:3.90.79.10 2 124 1.5E-33 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS12520 27d5b334348717901e09a6b168a0a18f 127 ProSitePatterns PS00893 Nudix box signature. 34 55 - T 10-11-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A4G23_RS12520 27d5b334348717901e09a6b168a0a18f 127 SUPERFAMILY SSF55811 2 124 1.07E-30 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS12520 27d5b334348717901e09a6b168a0a18f 127 Pfam PF00293 NUDIX domain 2 123 6.2E-20 T 10-11-2016 IPR000086 NUDIX hydrolase domain GO:0016787 A4G23_RS06445 f02935512b3f6e08228738bb56bde42a 251 SUPERFAMILY SSF56219 16 248 1.13E-25 T 10-11-2016 IPR005135 Endonuclease/exonuclease/phosphatase A4G23_RS06445 f02935512b3f6e08228738bb56bde42a 251 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 22 238 3.0E-12 T 10-11-2016 IPR005135 Endonuclease/exonuclease/phosphatase A4G23_RS06445 f02935512b3f6e08228738bb56bde42a 251 Gene3D G3DSA:3.60.10.10 18 245 1.9E-8 T 10-11-2016 IPR005135 Endonuclease/exonuclease/phosphatase A4G23_RS20730 7b876ff084c5ce99363178d47a9bdb7d 146 PIRSF PIRSF014972 14 143 6.1E-30 T 10-11-2016 IPR025540 Fluoroacetyl-CoA thioesterase A4G23_RS20730 7b876ff084c5ce99363178d47a9bdb7d 146 Gene3D G3DSA:3.10.129.10 13 139 8.6E-30 T 10-11-2016 IPR029069 HotDog domain A4G23_RS20730 7b876ff084c5ce99363178d47a9bdb7d 146 SUPERFAMILY SSF54637 16 135 5.14E-33 T 10-11-2016 IPR029069 HotDog domain A4G23_RS04100 9c5bf0bcc612db43035f16a082e94405 375 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 25 371 45.453 T 10-11-2016 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 A4G23_RS04100 9c5bf0bcc612db43035f16a082e94405 375 SUPERFAMILY SSF46589 29 115 1.46E-13 T 10-11-2016 IPR010978 tRNA-binding arm GO:0000166 A4G23_RS04100 9c5bf0bcc612db43035f16a082e94405 375 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 37 104 4.9E-15 T 10-11-2016 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 A4G23_RS04100 9c5bf0bcc612db43035f16a082e94405 375 Gene3D G3DSA:3.30.930.10 25 372 3.1E-118 T 10-11-2016 A4G23_RS04100 9c5bf0bcc612db43035f16a082e94405 375 SUPERFAMILY SSF55681 109 372 4.68E-76 T 10-11-2016 A4G23_RS04100 9c5bf0bcc612db43035f16a082e94405 375 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 67 369 2.0E-86 T 10-11-2016 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 A4G23_RS04100 9c5bf0bcc612db43035f16a082e94405 375 Pfam PF01409 tRNA synthetases class II core domain (F) 109 370 4.9E-102 T 10-11-2016 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 A4G23_RS14830 d409b46d57bbfc915ea82cab4e6a58b2 276 Pfam PF00753 Metallo-beta-lactamase superfamily 37 204 3.0E-13 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS14830 d409b46d57bbfc915ea82cab4e6a58b2 276 SMART SM00849 39 204 3.2E-25 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS14830 d409b46d57bbfc915ea82cab4e6a58b2 276 Gene3D G3DSA:3.60.15.10 23 234 4.6E-46 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS14830 d409b46d57bbfc915ea82cab4e6a58b2 276 SUPERFAMILY SSF56281 28 275 6.16E-49 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS19080 895d23df202fd1ff738b6ff48410f818 195 SUPERFAMILY SSF53597 2 194 6.54E-25 T 10-11-2016 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 A4G23_RS19080 895d23df202fd1ff738b6ff48410f818 195 Gene3D G3DSA:3.40.430.10 3 193 4.6E-25 T 10-11-2016 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 A4G23_RS19080 895d23df202fd1ff738b6ff48410f818 195 Pfam PF01872 RibD C-terminal domain 3 188 1.7E-9 T 10-11-2016 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 A4G23_RS23765 3a2619860434683f5019e82236d596d9 400 Gene3D G3DSA:3.50.50.60 259 331 1.1E-49 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS23765 3a2619860434683f5019e82236d596d9 400 Gene3D G3DSA:3.50.50.60 5 119 1.1E-49 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS23765 3a2619860434683f5019e82236d596d9 400 SUPERFAMILY SSF51905 6 104 3.69E-30 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS23765 3a2619860434683f5019e82236d596d9 400 SUPERFAMILY SSF51905 201 331 3.69E-30 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS23765 3a2619860434683f5019e82236d596d9 400 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 305 5.0E-19 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS23765 3a2619860434683f5019e82236d596d9 400 Gene3D G3DSA:3.50.50.60 202 252 2.2E-6 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS06750 d19deb6ed92f68b30eb2832ddea0c580 304 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 77 129 7.0E-21 T 10-11-2016 A4G23_RS06750 d19deb6ed92f68b30eb2832ddea0c580 304 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 73 88 - T 10-11-2016 IPR020605 Octanoyltransferase, conserved site GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 A4G23_RS06750 d19deb6ed92f68b30eb2832ddea0c580 304 Hamap MF_00013 Octanoyltransferase [lipB]. 3 253 33.36 T 10-11-2016 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 A4G23_RS06750 d19deb6ed92f68b30eb2832ddea0c580 304 SUPERFAMILY SSF55681 14 132 1.99E-61 T 10-11-2016 A4G23_RS06750 d19deb6ed92f68b30eb2832ddea0c580 304 SUPERFAMILY SSF55681 178 252 1.99E-61 T 10-11-2016 A4G23_RS06750 d19deb6ed92f68b30eb2832ddea0c580 304 Gene3D G3DSA:3.90.1550.10 14 136 7.7E-77 T 10-11-2016 A4G23_RS06750 d19deb6ed92f68b30eb2832ddea0c580 304 Gene3D G3DSA:3.90.1550.10 179 250 7.7E-77 T 10-11-2016 A4G23_RS10070 c88359c23cb82eb19039917b771fbbb5 217 SUPERFAMILY SSF50447 4 87 5.65E-9 T 10-11-2016 IPR009000 Translation protein, beta-barrel domain A4G23_RS10070 c88359c23cb82eb19039917b771fbbb5 217 SUPERFAMILY SSF55186 89 214 1.57E-20 T 10-11-2016 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 A4G23_RS10070 c88359c23cb82eb19039917b771fbbb5 217 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 170 199 2.3E-4 T 10-11-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 A4G23_RS04840 a6c62dc1f744e93b25965a3d1b25e5f9 482 SUPERFAMILY SSF52540 179 477 2.6E-60 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS04840 a6c62dc1f744e93b25965a3d1b25e5f9 482 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 395 473 7.5E-24 T 10-11-2016 IPR032859 GTPase Der, C-terminal KH-domain-like A4G23_RS04840 a6c62dc1f744e93b25965a3d1b25e5f9 482 PIRSF PIRSF006485 43 481 1.5E-158 T 10-11-2016 IPR016484 GTP-binding protein EngA GO:0005525 A4G23_RS04840 a6c62dc1f744e93b25965a3d1b25e5f9 482 SMART SM00382 218 363 0.013 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS04840 a6c62dc1f744e93b25965a3d1b25e5f9 482 SMART SM00382 43 179 0.051 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS04840 a6c62dc1f744e93b25965a3d1b25e5f9 482 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 47 198 1.8E-23 T 10-11-2016 IPR005225 Small GTP-binding protein domain GO:0005525 A4G23_RS04840 a6c62dc1f744e93b25965a3d1b25e5f9 482 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 220 386 2.1E-21 T 10-11-2016 IPR005225 Small GTP-binding protein domain GO:0005525 A4G23_RS04840 a6c62dc1f744e93b25965a3d1b25e5f9 482 Gene3D G3DSA:3.30.300.20 401 475 7.9E-27 T 10-11-2016 IPR015946 K homology domain-like, alpha/beta A4G23_RS04840 a6c62dc1f744e93b25965a3d1b25e5f9 482 Gene3D G3DSA:3.40.50.300 220 400 5.7E-45 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS04840 a6c62dc1f744e93b25965a3d1b25e5f9 482 Gene3D G3DSA:3.40.50.300 45 210 1.6E-42 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS04840 a6c62dc1f744e93b25965a3d1b25e5f9 482 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 222 242 6.8E-6 T 10-11-2016 IPR006073 GTP binding domain GO:0005525 A4G23_RS04840 a6c62dc1f744e93b25965a3d1b25e5f9 482 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 271 286 6.8E-6 T 10-11-2016 IPR006073 GTP binding domain GO:0005525 A4G23_RS04840 a6c62dc1f744e93b25965a3d1b25e5f9 482 Pfam PF01926 50S ribosome-binding GTPase 47 161 1.9E-24 T 10-11-2016 IPR006073 GTP binding domain GO:0005525 A4G23_RS04840 a6c62dc1f744e93b25965a3d1b25e5f9 482 Pfam PF01926 50S ribosome-binding GTPase 221 339 2.3E-21 T 10-11-2016 IPR006073 GTP binding domain GO:0005525 A4G23_RS04840 a6c62dc1f744e93b25965a3d1b25e5f9 482 SUPERFAMILY SSF52540 46 209 3.88E-44 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS04840 a6c62dc1f744e93b25965a3d1b25e5f9 482 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 45 473 2.9E-158 T 10-11-2016 IPR016484 GTP-binding protein EngA GO:0005525 A4G23_RS04840 a6c62dc1f744e93b25965a3d1b25e5f9 482 Hamap MF_00195 GTPase Der [der]. 44 476 35.587 T 10-11-2016 IPR016484 GTP-binding protein EngA GO:0005525 A4G23_RS19355 0bd2ee304d2b96f08f7ad4a6b3a252fe 203 SUPERFAMILY SSF52980 18 167 3.65E-14 T 10-11-2016 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A4G23_RS19355 0bd2ee304d2b96f08f7ad4a6b3a252fe 203 Pfam PF05685 Putative restriction endonuclease 26 193 1.5E-20 T 10-11-2016 IPR008538 Domain of unknown function DUF820 A4G23_RS19355 0bd2ee304d2b96f08f7ad4a6b3a252fe 203 Gene3D G3DSA:3.90.1570.10 18 168 5.9E-14 T 10-11-2016 IPR012296 Nuclease, putative, TT1808 A4G23_RS08235 9506ce30c754b771c36100044d062d1e 208 Gene3D G3DSA:1.10.357.10 2 205 5.0E-39 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS08235 9506ce30c754b771c36100044d062d1e 208 SUPERFAMILY SSF48498 87 204 6.53E-15 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS08235 9506ce30c754b771c36100044d062d1e 208 SUPERFAMILY SSF46689 2 73 5.49E-14 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS08235 9506ce30c754b771c36100044d062d1e 208 Pfam PF13977 Bacterial transcriptional repressor 89 203 2.6E-12 T 10-11-2016 A4G23_RS08235 9506ce30c754b771c36100044d062d1e 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 57 5.7E-8 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS25450 4e930f309c28a809cdee770b632f8a8c 352 Pfam PF16912 Glucose dehydrogenase C-terminus 145 348 5.2E-63 T 10-11-2016 IPR031640 Glucose dehydrogenase, C-terminal KEGG: 00030+1.1.1.47 A4G23_RS25450 4e930f309c28a809cdee770b632f8a8c 352 SUPERFAMILY SSF51735 173 297 8.64E-13 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS25450 4e930f309c28a809cdee770b632f8a8c 352 Gene3D G3DSA:3.90.180.10 1 189 2.8E-28 T 10-11-2016 IPR011032 GroES-like A4G23_RS25450 4e930f309c28a809cdee770b632f8a8c 352 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 137 3.9E-12 T 10-11-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A4G23_RS25450 4e930f309c28a809cdee770b632f8a8c 352 Gene3D G3DSA:3.40.50.720 190 277 4.8E-12 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS25450 4e930f309c28a809cdee770b632f8a8c 352 SUPERFAMILY SSF50129 4 183 8.52E-31 T 10-11-2016 IPR011032 GroES-like A4G23_RS01725 649b207def8141db6439c2f0446274e0 672 Pfam PF13185 GAF domain 87 230 3.2E-17 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS01725 649b207def8141db6439c2f0446274e0 672 Gene3D G3DSA:3.30.450.40 65 245 1.5E-34 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS01725 649b207def8141db6439c2f0446274e0 672 SMART SM00065 88 239 1.1E-18 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS01725 649b207def8141db6439c2f0446274e0 672 SUPERFAMILY SSF55781 71 254 5.23E-29 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS01725 649b207def8141db6439c2f0446274e0 672 Pfam PF13556 PucR C-terminal helix-turn-helix domain 605 663 1.7E-15 T 10-11-2016 IPR025736 PucR C-terminal helix-turn-helix domain A4G23_RS12460 92cbe6b443319a3f5183128476c45348 278 SUPERFAMILY SSF46894 125 221 4.25E-30 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS12460 92cbe6b443319a3f5183128476c45348 278 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 219 1.3E-28 T 10-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4G23_RS12460 92cbe6b443319a3f5183128476c45348 278 Gene3D G3DSA:1.10.10.10 125 222 1.5E-36 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS12460 92cbe6b443319a3f5183128476c45348 278 SMART SM00862 145 219 2.2E-30 T 10-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4G23_RS24675 966912b5b7452d348af88dc566cd6299 163 Hamap MF_00612 UPF0225 protein YchJ [ychJ]. 38 161 27.89 T 10-11-2016 IPR023006 Uncharacterised protein family UPF0225 A4G23_RS24675 966912b5b7452d348af88dc566cd6299 163 SUPERFAMILY SSF54427 62 162 2.1E-31 T 10-11-2016 IPR032710 NTF2-like domain A4G23_RS24675 966912b5b7452d348af88dc566cd6299 163 Gene3D G3DSA:3.10.450.50 41 162 8.0E-41 T 10-11-2016 IPR032710 NTF2-like domain A4G23_RS14780 e8106506bb242a9bfb38e7f14e760253 262 PRINTS PR00164 ABC-2 type transport system membrane protein signature 204 223 1.2E-5 T 10-11-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 A4G23_RS14780 e8106506bb242a9bfb38e7f14e760253 262 PRINTS PR00164 ABC-2 type transport system membrane protein signature 107 132 1.2E-5 T 10-11-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 A4G23_RS14780 e8106506bb242a9bfb38e7f14e760253 262 PRINTS PR00164 ABC-2 type transport system membrane protein signature 184 203 1.2E-5 T 10-11-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 A4G23_RS14780 e8106506bb242a9bfb38e7f14e760253 262 PRINTS PR00164 ABC-2 type transport system membrane protein signature 29 50 1.2E-5 T 10-11-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 A4G23_RS14780 e8106506bb242a9bfb38e7f14e760253 262 PIRSF PIRSF006648 2 261 8.4E-67 T 10-11-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 A4G23_RS14780 e8106506bb242a9bfb38e7f14e760253 262 Pfam PF01061 ABC-2 type transporter 13 226 5.7E-26 T 10-11-2016 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A4G23_RS14520 caefca9135bde8656f27353261748ade 139 Pfam PF11349 Protein of unknown function (DUF3151) 10 135 8.8E-58 T 10-11-2016 IPR014487 Protein of unknown function DUF3151 A4G23_RS14520 caefca9135bde8656f27353261748ade 139 PIRSF PIRSF017349 1 139 4.3E-59 T 10-11-2016 IPR014487 Protein of unknown function DUF3151 A4G23_RS12490 f0f32ab3b2008c3d584ce92413ddc531 327 Gene3D G3DSA:3.40.630.30 182 323 3.4E-30 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS12490 f0f32ab3b2008c3d584ce92413ddc531 327 Hamap MF_01698 Mycothiol acetyltransferase [mshD]. 16 325 36.173 T 10-11-2016 IPR017813 Mycothiol acetyltransferase GO:0016747 A4G23_RS12490 f0f32ab3b2008c3d584ce92413ddc531 327 Gene3D G3DSA:3.40.630.30 20 161 1.1E-11 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS12490 f0f32ab3b2008c3d584ce92413ddc531 327 Pfam PF00583 Acetyltransferase (GNAT) family 238 315 2.1E-12 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS12490 f0f32ab3b2008c3d584ce92413ddc531 327 Pfam PF00583 Acetyltransferase (GNAT) family 86 154 1.2E-5 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS12490 f0f32ab3b2008c3d584ce92413ddc531 327 TIGRFAM TIGR03448 mycothiol_MshD: mycothiol synthase 21 323 2.6E-111 T 10-11-2016 IPR017813 Mycothiol acetyltransferase GO:0016747 A4G23_RS12490 f0f32ab3b2008c3d584ce92413ddc531 327 PIRSF PIRSF021524 10 327 1.0E-104 T 10-11-2016 IPR017813 Mycothiol acetyltransferase GO:0016747 A4G23_RS12490 f0f32ab3b2008c3d584ce92413ddc531 327 SUPERFAMILY SSF55729 16 322 3.59E-45 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS10350 ccd9aa5a538e1b26b9767695f33aaf45 90 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 3 71 3.3E-16 T 10-11-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM A4G23_RS10350 ccd9aa5a538e1b26b9767695f33aaf45 90 Gene3D G3DSA:3.40.1620.10 3 52 4.6E-22 T 10-11-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM A4G23_RS10350 ccd9aa5a538e1b26b9767695f33aaf45 90 SUPERFAMILY SSF143120 4 63 3.66E-13 T 10-11-2016 A4G23_RS10350 ccd9aa5a538e1b26b9767695f33aaf45 90 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 5 52 2.7E-13 T 10-11-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM A4G23_RS10215 7e6f99140b42ce1e72b6c03faf75ba15 68 Pfam PF14117 Domain of unknown function (DUF4287) 7 63 1.9E-29 T 10-11-2016 IPR025629 Protein of unknown function DUF4287 A4G23_RS07145 e8d4feddcb19e0794f438f368808f336 306 SMART SM00646 169 301 2.8E-10 T 10-11-2016 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A4G23_RS07145 e8d4feddcb19e0794f438f368808f336 306 SUPERFAMILY SSF53187 83 304 5.96E-28 T 10-11-2016 A4G23_RS07145 e8d4feddcb19e0794f438f368808f336 306 Gene3D G3DSA:3.40.630.40 83 304 5.9E-33 T 10-11-2016 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A4G23_RS07145 e8d4feddcb19e0794f438f368808f336 306 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 86 300 1.2E-30 T 10-11-2016 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A4G23_RS03655 20cfddec6bfb946046e8bc8938d556cc 234 Gene3D G3DSA:3.20.180.10 138 231 1.5E-8 T 10-11-2016 IPR019595 Domain of unknown function DUF2470 A4G23_RS03655 20cfddec6bfb946046e8bc8938d556cc 234 SUPERFAMILY SSF50475 69 230 3.02E-14 T 10-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 A4G23_RS03655 20cfddec6bfb946046e8bc8938d556cc 234 Pfam PF10615 Protein of unknown function (DUF2470) 143 225 2.8E-6 T 10-11-2016 IPR019595 Domain of unknown function DUF2470 A4G23_RS21480 9df2a5e525fe6252096d6f20d8c35fff 401 SUPERFAMILY SSF103473 13 394 7.98E-33 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS21480 9df2a5e525fe6252096d6f20d8c35fff 401 Gene3D G3DSA:1.20.1250.20 217 391 4.4E-18 T 10-11-2016 A4G23_RS21480 9df2a5e525fe6252096d6f20d8c35fff 401 Gene3D G3DSA:1.20.1250.20 17 193 2.0E-8 T 10-11-2016 A4G23_RS21480 9df2a5e525fe6252096d6f20d8c35fff 401 Pfam PF07690 Major Facilitator Superfamily 30 294 3.8E-14 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS04340 39e6cef1979daf7cd3757b8bcb0bafe9 301 Pfam PF12705 PD-(D/E)XK nuclease superfamily 25 273 1.2E-38 T 10-11-2016 A4G23_RS04340 39e6cef1979daf7cd3757b8bcb0bafe9 301 SUPERFAMILY SSF52980 51 208 1.34E-9 T 10-11-2016 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A4G23_RS21420 1726725b12f8853bbd3623efa5dab05d 455 SUPERFAMILY SSF63411 17 218 3.67E-37 T 10-11-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A4G23_RS21420 1726725b12f8853bbd3623efa5dab05d 455 Gene3D G3DSA:3.30.830.10 22 227 2.4E-32 T 10-11-2016 IPR011237 Peptidase M16 domain GO:0046872 A4G23_RS21420 1726725b12f8853bbd3623efa5dab05d 455 Pfam PF00675 Insulinase (Peptidase family M16) 33 163 3.2E-13 T 10-11-2016 IPR011765 Peptidase M16, N-terminal A4G23_RS21420 1726725b12f8853bbd3623efa5dab05d 455 Pfam PF05193 Peptidase M16 inactive domain 185 368 1.9E-21 T 10-11-2016 IPR007863 Peptidase M16, C-terminal A4G23_RS21420 1726725b12f8853bbd3623efa5dab05d 455 Gene3D G3DSA:3.30.830.10 247 435 3.1E-12 T 10-11-2016 IPR011237 Peptidase M16 domain GO:0046872 A4G23_RS21420 1726725b12f8853bbd3623efa5dab05d 455 SUPERFAMILY SSF63411 247 446 2.62E-22 T 10-11-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A4G23_RS12335 d8b014465622828102d9ddccdbb3d88b 388 SUPERFAMILY SSF103473 8 376 9.81E-40 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS12335 d8b014465622828102d9ddccdbb3d88b 388 Gene3D G3DSA:1.20.1250.20 12 186 1.3E-23 T 10-11-2016 A4G23_RS12335 d8b014465622828102d9ddccdbb3d88b 388 Gene3D G3DSA:1.20.1250.20 210 375 3.9E-6 T 10-11-2016 A4G23_RS12335 d8b014465622828102d9ddccdbb3d88b 388 Pfam PF07690 Major Facilitator Superfamily 16 343 8.7E-29 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS06660 94cace2c05d99c9fc912539a4ca9d671 399 Gene3D G3DSA:3.60.15.10 2 75 1.8E-12 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS06660 94cace2c05d99c9fc912539a4ca9d671 399 SUPERFAMILY SSF56281 2 136 6.09E-6 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS06660 94cace2c05d99c9fc912539a4ca9d671 399 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 224 395 4.7E-51 T 10-11-2016 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 A4G23_RS06660 94cace2c05d99c9fc912539a4ca9d671 399 Gene3D G3DSA:3.40.50.300 224 397 4.7E-53 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS06660 94cace2c05d99c9fc912539a4ca9d671 399 SUPERFAMILY SSF52540 224 396 1.46E-37 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05740 130b721a81d4387c522c96e69a132a10 192 Gene3D G3DSA:2.60.60.30 21 182 1.2E-46 T 10-11-2016 A4G23_RS05740 130b721a81d4387c522c96e69a132a10 192 Pfam PF02342 TerD domain 2 179 2.5E-43 T 10-11-2016 IPR003325 TerD domain GO:0006950 A4G23_RS10665 0ce93bb3c8cd679937df496392c5295e 412 SMART SM01208 198 276 2.7E-18 T 10-11-2016 IPR011098 G5 domain A4G23_RS10665 0ce93bb3c8cd679937df496392c5295e 412 Pfam PF06737 Transglycosylase-like domain 333 406 2.6E-23 T 10-11-2016 IPR010618 Transglycosylase-like A4G23_RS10665 0ce93bb3c8cd679937df496392c5295e 412 SUPERFAMILY SSF53955 333 409 1.48E-24 T 10-11-2016 IPR023346 Lysozyme-like domain A4G23_RS10665 0ce93bb3c8cd679937df496392c5295e 412 Pfam PF07501 G5 domain 203 274 2.1E-17 T 10-11-2016 IPR011098 G5 domain A4G23_RS10665 0ce93bb3c8cd679937df496392c5295e 412 Gene3D G3DSA:1.10.530.10 326 410 4.4E-29 T 10-11-2016 A4G23_RS10665 0ce93bb3c8cd679937df496392c5295e 412 Pfam PF03990 Domain of unknown function (DUF348) 89 125 8.3E-6 T 10-11-2016 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 A4G23_RS10665 0ce93bb3c8cd679937df496392c5295e 412 Pfam PF03990 Domain of unknown function (DUF348) 145 183 1.7E-9 T 10-11-2016 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 A4G23_RS10665 0ce93bb3c8cd679937df496392c5295e 412 Pfam PF03990 Domain of unknown function (DUF348) 31 71 1.7E-12 T 10-11-2016 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 A4G23_RS20230 2d60b6050b49f08f00a303c9ed64edb1 193 SUPERFAMILY SSF52540 16 190 3.3E-22 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS20230 2d60b6050b49f08f00a303c9ed64edb1 193 Gene3D G3DSA:3.40.50.300 11 186 1.3E-14 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS20230 2d60b6050b49f08f00a303c9ed64edb1 193 Pfam PF03029 Conserved hypothetical ATP binding protein 21 188 5.9E-28 T 10-11-2016 IPR004130 GPN-loop GTPase A4G23_RS21980 31d63b4161ddf6aa55eabe0866f54895 65 Pfam PF04149 Domain of unknown function (DUF397) 14 65 6.5E-22 T 10-11-2016 IPR007278 Domain of unknown function DUF397 A4G23_RS27200 6c514c422555e3032d91c2136f53694d 454 SUPERFAMILY SSF56059 107 322 1.34E-28 T 10-11-2016 A4G23_RS27200 6c514c422555e3032d91c2136f53694d 454 Gene3D G3DSA:3.30.470.20 106 319 2.0E-20 T 10-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 A4G23_RS21580 cb85ec6d853d998547a3d0edca54e4c9 255 Pfam PF13359 DDE superfamily endonuclease 102 249 1.5E-23 T 10-11-2016 IPR027806 Harbinger transposase-derived nuclease domain A4G23_RS21580 cb85ec6d853d998547a3d0edca54e4c9 255 Pfam PF13613 Helix-turn-helix of DDE superfamily endonuclease 34 85 2.1E-13 T 10-11-2016 IPR027805 Transposase, Helix-turn-helix domain A4G23_RS21580 cb85ec6d853d998547a3d0edca54e4c9 255 Gene3D G3DSA:1.10.10.60 49 73 2.8E-6 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS08715 c5e7fc64babd8ace1249570585a7e105 249 SMART SM00421 186 243 0.0013 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS08715 c5e7fc64babd8ace1249570585a7e105 249 Gene3D G3DSA:1.10.10.10 182 248 3.8E-9 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS08715 c5e7fc64babd8ace1249570585a7e105 249 SUPERFAMILY SSF46894 176 249 1.63E-7 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS15920 ed033048ef034fcceab81d59e590c2bb 438 Pfam PF00375 Sodium:dicarboxylate symporter family 17 405 4.1E-113 T 10-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4G23_RS15920 ed033048ef034fcceab81d59e590c2bb 438 Gene3D G3DSA:1.10.3860.10 13 408 2.6E-111 T 10-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4G23_RS15920 ed033048ef034fcceab81d59e590c2bb 438 PRINTS PR00173 Glutamate-aspartate symporter signature 299 325 9.5E-29 T 10-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4G23_RS15920 ed033048ef034fcceab81d59e590c2bb 438 PRINTS PR00173 Glutamate-aspartate symporter signature 334 353 9.5E-29 T 10-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4G23_RS15920 ed033048ef034fcceab81d59e590c2bb 438 PRINTS PR00173 Glutamate-aspartate symporter signature 360 380 9.5E-29 T 10-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4G23_RS15920 ed033048ef034fcceab81d59e590c2bb 438 PRINTS PR00173 Glutamate-aspartate symporter signature 197 216 9.5E-29 T 10-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4G23_RS15920 ed033048ef034fcceab81d59e590c2bb 438 PRINTS PR00173 Glutamate-aspartate symporter signature 87 112 9.5E-29 T 10-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4G23_RS15920 ed033048ef034fcceab81d59e590c2bb 438 PRINTS PR00173 Glutamate-aspartate symporter signature 15 35 9.5E-29 T 10-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4G23_RS15920 ed033048ef034fcceab81d59e590c2bb 438 PRINTS PR00173 Glutamate-aspartate symporter signature 57 77 9.5E-29 T 10-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4G23_RS15920 ed033048ef034fcceab81d59e590c2bb 438 SUPERFAMILY SSF118215 17 405 4.84E-103 T 10-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4G23_RS13615 d1d2834da5ab08565a27647c5803eb67 445 PIRSF PIRSF006603 1 445 1.2E-62 T 10-11-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A4G23_RS13615 d1d2834da5ab08565a27647c5803eb67 445 Pfam PF01554 MatE 243 398 5.2E-21 T 10-11-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A4G23_RS13615 d1d2834da5ab08565a27647c5803eb67 445 Pfam PF01554 MatE 25 185 7.5E-25 T 10-11-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A4G23_RS13615 d1d2834da5ab08565a27647c5803eb67 445 TIGRFAM TIGR00797 matE: MATE efflux family protein 25 415 1.2E-103 T 10-11-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A4G23_RS19930 8a0964654ddc01cf827ffbf5b81a0a26 130 Gene3D G3DSA:3.40.50.1010 6 126 8.7E-8 T 10-11-2016 IPR029060 PIN domain-like A4G23_RS19930 8a0964654ddc01cf827ffbf5b81a0a26 130 SUPERFAMILY SSF88723 5 124 2.94E-12 T 10-11-2016 IPR029060 PIN domain-like A4G23_RS09675 0978088f8fb4892feb695b788c8430c3 765 Gene3D G3DSA:3.40.50.300 608 750 8.2E-22 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS09675 0978088f8fb4892feb695b788c8430c3 765 Pfam PF13538 UvrD-like helicase C-terminal domain 705 747 3.2E-8 T 10-11-2016 IPR027785 UvrD-like helicase C-terminal domain A4G23_RS09675 0978088f8fb4892feb695b788c8430c3 765 Pfam PF13245 Part of AAA domain 234 290 2.4E-13 T 10-11-2016 A4G23_RS09675 0978088f8fb4892feb695b788c8430c3 765 Pfam PF00580 UvrD/REP helicase N-terminal domain 532 582 3.5E-6 T 10-11-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 A4G23_RS09675 0978088f8fb4892feb695b788c8430c3 765 Gene3D G3DSA:3.40.50.300 227 294 2.1E-40 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS09675 0978088f8fb4892feb695b788c8430c3 765 Gene3D G3DSA:3.40.50.300 427 584 2.1E-40 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS09675 0978088f8fb4892feb695b788c8430c3 765 SUPERFAMILY SSF52540 516 752 1.73E-49 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS09675 0978088f8fb4892feb695b788c8430c3 765 SUPERFAMILY SSF52540 220 298 1.73E-49 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS09675 0978088f8fb4892feb695b788c8430c3 765 SUPERFAMILY SSF52540 381 435 1.73E-49 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS21230 b5d1fe6458c1d8093c5e6a954567b24e 244 SUPERFAMILY SSF53213 29 243 7.72E-9 T 10-11-2016 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 A4G23_RS04300 b2f08fe0ededc4fccd59a78df8ced395 198 Pfam PF02945 Recombination endonuclease VII 108 180 8.7E-22 T 10-11-2016 IPR004211 Recombination endonuclease VII A4G23_RS04300 b2f08fe0ededc4fccd59a78df8ced395 198 SUPERFAMILY SSF54060 110 184 2.71E-17 T 10-11-2016 A4G23_RS14810 33ebca2c27dd5b6f8f452d26e8898463 424 Pfam PF02374 Anion-transporting ATPase 12 283 3.7E-26 T 10-11-2016 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 A4G23_RS14810 33ebca2c27dd5b6f8f452d26e8898463 424 Gene3D G3DSA:3.40.50.300 8 170 5.8E-51 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS14810 33ebca2c27dd5b6f8f452d26e8898463 424 Gene3D G3DSA:3.40.50.300 211 288 5.8E-51 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS14810 33ebca2c27dd5b6f8f452d26e8898463 424 SUPERFAMILY SSF52540 224 285 1.66E-35 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS14810 33ebca2c27dd5b6f8f452d26e8898463 424 SUPERFAMILY SSF52540 9 182 1.66E-35 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS13770 fc33067114f12f4a49ebc772a0b7e9cf 240 Pfam PF12679 ABC-2 family transporter protein 55 163 1.1E-8 T 10-11-2016 IPR032688 ABC-2 family transporter protein GO:0006810 A4G23_RS12400 d9b7a6b36e291fd92a13c290cc9a99a9 190 Pfam PF08768 Domain of unknown function (DUF1794) 12 164 2.3E-48 T 10-11-2016 IPR014878 Domain of unknown function DUF1794 A4G23_RS12400 d9b7a6b36e291fd92a13c290cc9a99a9 190 SUPERFAMILY SSF50814 7 165 1.71E-41 T 10-11-2016 IPR011038 Calycin-like A4G23_RS12400 d9b7a6b36e291fd92a13c290cc9a99a9 190 Hamap MF_01297 UPF0678 fatty acid-binding protein-like protein . 4 166 32.479 T 10-11-2016 IPR022939 Uncharacterised protein family UPF0678 A4G23_RS19130 f03ccc69866d867493fd9c66b94c83ea 142 Gene3D G3DSA:2.10.109.10 14 105 7.1E-19 T 10-11-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain A4G23_RS19130 f03ccc69866d867493fd9c66b94c83ea 142 TIGRFAM TIGR02754 sod_Ni_protease: nickel-type superoxide dismutase maturation protease 17 101 6.8E-27 T 10-11-2016 IPR014124 Peptidase S26A, superoxide dismutase maturation protease, nickel-type A4G23_RS19130 f03ccc69866d867493fd9c66b94c83ea 142 SUPERFAMILY SSF51306 13 105 4.84E-23 T 10-11-2016 IPR015927 Peptidase S24/S26A/S26B/S26C A4G23_RS19130 f03ccc69866d867493fd9c66b94c83ea 142 Pfam PF00717 Peptidase S24-like 17 77 1.1E-11 T 10-11-2016 IPR019759 Peptidase S24/S26A/S26B A4G23_RS12250 3f8449ca7319001a4c92c453b70c7536 162 Pfam PF10722 Putative bacterial sensory transduction regulator 5 127 2.2E-17 T 10-11-2016 IPR019660 Putative sensory transduction regulator YbjN A4G23_RS12250 3f8449ca7319001a4c92c453b70c7536 162 SUPERFAMILY SSF69635 6 129 5.23E-30 T 10-11-2016 A4G23_RS12250 3f8449ca7319001a4c92c453b70c7536 162 Gene3D G3DSA:3.30.1460.10 7 138 5.8E-15 T 10-11-2016 A4G23_RS12085 8b9128d046bc609597c8094a47a63428 170 Pfam PF00583 Acetyltransferase (GNAT) family 70 148 7.1E-9 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS12085 8b9128d046bc609597c8094a47a63428 170 Gene3D G3DSA:3.40.630.30 39 169 3.5E-21 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS12085 8b9128d046bc609597c8094a47a63428 170 SUPERFAMILY SSF55729 22 168 2.7E-21 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS26465 1650b32c4f4c596955de0d9731f2419b 506 Pfam PF04984 Phage tail sheath protein 302 494 4.9E-28 T 10-11-2016 IPR007067 Tail sheath protein A4G23_RS26465 1650b32c4f4c596955de0d9731f2419b 506 Pfam PF04984 Phage tail sheath protein 2 128 5.9E-10 T 10-11-2016 IPR007067 Tail sheath protein A4G23_RS26050 66a0d256098c1d3f0b6258697cf35daa 966 SUPERFAMILY SSF48452 731 767 4.08E-5 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS26050 66a0d256098c1d3f0b6258697cf35daa 966 SUPERFAMILY SSF48452 831 871 4.08E-5 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS26050 66a0d256098c1d3f0b6258697cf35daa 966 SUPERFAMILY SSF48452 653 684 4.08E-5 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS26050 66a0d256098c1d3f0b6258697cf35daa 966 SUPERFAMILY SSF48452 417 452 4.08E-5 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS26050 66a0d256098c1d3f0b6258697cf35daa 966 Gene3D G3DSA:1.10.10.10 890 956 4.3E-10 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS26050 66a0d256098c1d3f0b6258697cf35daa 966 SUPERFAMILY SSF52540 14 81 5.25E-12 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS26050 66a0d256098c1d3f0b6258697cf35daa 966 SUPERFAMILY SSF52540 124 243 5.25E-12 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS26050 66a0d256098c1d3f0b6258697cf35daa 966 Gene3D G3DSA:3.40.50.300 16 87 1.3E-5 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS26050 66a0d256098c1d3f0b6258697cf35daa 966 Gene3D G3DSA:3.40.50.300 135 199 1.3E-5 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS26050 66a0d256098c1d3f0b6258697cf35daa 966 SMART SM00421 908 964 0.0012 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS26050 66a0d256098c1d3f0b6258697cf35daa 966 Gene3D G3DSA:1.25.40.10 570 885 1.7E-11 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS26050 66a0d256098c1d3f0b6258697cf35daa 966 Pfam PF13191 AAA ATPase domain 15 185 6.4E-18 T 10-11-2016 A4G23_RS26050 66a0d256098c1d3f0b6258697cf35daa 966 SUPERFAMILY SSF46894 899 956 3.37E-7 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS27195 2151a901e882642cddbb1ba97ab1790f 115 Gene3D G3DSA:3.10.450.50 8 110 2.2E-15 T 10-11-2016 IPR032710 NTF2-like domain A4G23_RS27195 2151a901e882642cddbb1ba97ab1790f 115 Pfam PF12680 SnoaL-like domain 6 105 3.2E-14 T 10-11-2016 IPR009959 Polyketide cyclase SnoaL-like domain A4G23_RS27195 2151a901e882642cddbb1ba97ab1790f 115 SUPERFAMILY SSF54427 6 110 3.91E-19 T 10-11-2016 IPR032710 NTF2-like domain A4G23_RS18435 17efeddc3b06096e0b906b61a856c494 541 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 84 462 2.4E-49 T 10-11-2016 IPR000914 Solute-binding protein family 5 domain A4G23_RS18435 17efeddc3b06096e0b906b61a856c494 541 Gene3D G3DSA:3.10.105.10 322 512 2.0E-36 T 10-11-2016 A4G23_RS18435 17efeddc3b06096e0b906b61a856c494 541 Gene3D G3DSA:3.40.190.10 206 321 1.8E-26 T 10-11-2016 A4G23_RS18435 17efeddc3b06096e0b906b61a856c494 541 PIRSF PIRSF002741 12 536 2.2E-59 T 10-11-2016 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A4G23_RS18435 17efeddc3b06096e0b906b61a856c494 541 SUPERFAMILY SSF53850 35 538 1.39E-88 T 10-11-2016 A4G23_RS18435 17efeddc3b06096e0b906b61a856c494 541 Gene3D G3DSA:3.90.76.10 49 205 3.2E-31 T 10-11-2016 A4G23_RS22930 744249a3f9e9775d194607a7f956a231 432 SMART SM00474 46 212 1.7E-39 T 10-11-2016 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 A4G23_RS22930 744249a3f9e9775d194607a7f956a231 432 SUPERFAMILY SSF47819 232 342 1.18E-26 T 10-11-2016 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 A4G23_RS22930 744249a3f9e9775d194607a7f956a231 432 SUPERFAMILY SSF53098 32 249 7.59E-51 T 10-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 A4G23_RS22930 744249a3f9e9775d194607a7f956a231 432 Gene3D G3DSA:3.30.420.10 48 219 3.3E-7 T 10-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 A4G23_RS22930 744249a3f9e9775d194607a7f956a231 432 Gene3D G3DSA:1.10.150.80 260 308 4.5E-4 T 10-11-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 A4G23_RS22930 744249a3f9e9775d194607a7f956a231 432 Pfam PF01612 3'-5' exonuclease 49 212 9.2E-34 T 10-11-2016 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 A4G23_RS22930 744249a3f9e9775d194607a7f956a231 432 SMART SM00341 251 331 3.0E-17 T 10-11-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 A4G23_RS22930 744249a3f9e9775d194607a7f956a231 432 Pfam PF00570 HRDC domain 254 320 5.7E-15 T 10-11-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 A4G23_RS24590 6a6ae688a47453e829c5f0c6ee7d3511 401 SUPERFAMILY SSF48452 157 317 9.49E-7 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS24590 6a6ae688a47453e829c5f0c6ee7d3511 401 Gene3D G3DSA:1.10.260.40 1 41 6.0E-8 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS24590 6a6ae688a47453e829c5f0c6ee7d3511 401 Gene3D G3DSA:1.25.40.10 284 362 3.8E-4 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS24590 6a6ae688a47453e829c5f0c6ee7d3511 401 Gene3D G3DSA:1.25.40.10 160 235 3.8E-4 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS24590 6a6ae688a47453e829c5f0c6ee7d3511 401 SUPERFAMILY SSF47413 1 41 7.11E-6 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS24590 6a6ae688a47453e829c5f0c6ee7d3511 401 Pfam PF01381 Helix-turn-helix 1 41 4.2E-5 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS00385 7111e54ea7390ff571495633bb72adcd 165 Pfam PF11188 Protein of unknown function (DUF2975) 31 165 2.2E-31 T 10-11-2016 IPR021354 Protein of unknown function DUF2975 A4G23_RS25030 39d085d8b8dd61c55a7435e7a19ea59a 208 PRINTS PR01438 Universal stress protein signature 72 90 7.8E-14 T 10-11-2016 IPR006015 Universal stress protein A A4G23_RS25030 39d085d8b8dd61c55a7435e7a19ea59a 208 PRINTS PR01438 Universal stress protein signature 178 200 7.8E-14 T 10-11-2016 IPR006015 Universal stress protein A A4G23_RS25030 39d085d8b8dd61c55a7435e7a19ea59a 208 PRINTS PR01438 Universal stress protein signature 161 173 7.8E-14 T 10-11-2016 IPR006015 Universal stress protein A A4G23_RS25030 39d085d8b8dd61c55a7435e7a19ea59a 208 Gene3D G3DSA:3.40.50.620 74 198 8.2E-23 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS25030 39d085d8b8dd61c55a7435e7a19ea59a 208 Pfam PF00582 Universal stress protein family 74 199 9.4E-20 T 10-11-2016 IPR006016 UspA GO:0006950 A4G23_RS25030 39d085d8b8dd61c55a7435e7a19ea59a 208 SUPERFAMILY SSF52402 74 200 1.0E-20 T 10-11-2016 A4G23_RS24355 cc1b4ab338b251685ecc7e9ffaf3a49b 277 SUPERFAMILY SSF63992 1 267 1.29E-83 T 10-11-2016 IPR007035 Peptidase M55, D-aminopeptidase A4G23_RS24355 cc1b4ab338b251685ecc7e9ffaf3a49b 277 PIRSF PIRSF015853 1 274 2.2E-95 T 10-11-2016 IPR007035 Peptidase M55, D-aminopeptidase A4G23_RS24355 cc1b4ab338b251685ecc7e9ffaf3a49b 277 Gene3D G3DSA:3.40.50.10780 1 212 4.1E-75 T 10-11-2016 IPR027476 D-aminopeptidase, N-terminal A4G23_RS24355 cc1b4ab338b251685ecc7e9ffaf3a49b 277 Pfam PF04951 D-aminopeptidase 1 262 1.8E-92 T 10-11-2016 IPR007035 Peptidase M55, D-aminopeptidase A4G23_RS24355 cc1b4ab338b251685ecc7e9ffaf3a49b 277 Gene3D G3DSA:3.30.1360.130 216 267 7.4E-9 T 10-11-2016 A4G23_RS23010 1a8ebe007b3062334ef75f5de63ff90c 305 SUPERFAMILY SSF88713 82 303 3.71E-43 T 10-11-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A4G23_RS23010 1a8ebe007b3062334ef75f5de63ff90c 305 Pfam PF01522 Polysaccharide deacetylase 93 232 6.8E-25 T 10-11-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 A4G23_RS23010 1a8ebe007b3062334ef75f5de63ff90c 305 Gene3D G3DSA:3.20.20.370 88 303 4.8E-43 T 10-11-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 A4G23_RS18665 065ef5e0920d138643d60c769daeaa68 213 Gene3D G3DSA:1.10.10.60 11 54 1.1E-19 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS18665 065ef5e0920d138643d60c769daeaa68 213 SUPERFAMILY SSF46689 12 94 2.24E-21 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS18665 065ef5e0920d138643d60c769daeaa68 213 Gene3D G3DSA:1.10.10.60 55 78 6.4E-6 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS18665 065ef5e0920d138643d60c769daeaa68 213 Gene3D G3DSA:1.10.357.10 79 202 2.0E-19 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS18665 065ef5e0920d138643d60c769daeaa68 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 72 9.6E-17 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS18665 065ef5e0920d138643d60c769daeaa68 213 SUPERFAMILY SSF48498 92 204 8.9E-28 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS18665 065ef5e0920d138643d60c769daeaa68 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 3.8E-10 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS18665 065ef5e0920d138643d60c769daeaa68 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 3.8E-10 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS26865 18d5cfaa9b6bc2fa0a20708cc67d535c 135 SMART SM00960 8 98 1.8E-27 T 10-11-2016 IPR004942 Roadblock/LAMTOR2 domain A4G23_RS26865 18d5cfaa9b6bc2fa0a20708cc67d535c 135 Gene3D G3DSA:3.30.450.30 5 123 4.1E-27 T 10-11-2016 A4G23_RS26865 18d5cfaa9b6bc2fa0a20708cc67d535c 135 SUPERFAMILY SSF103196 6 126 8.55E-34 T 10-11-2016 A4G23_RS26865 18d5cfaa9b6bc2fa0a20708cc67d535c 135 Pfam PF03259 Roadblock/LC7 domain 7 98 2.5E-26 T 10-11-2016 IPR004942 Roadblock/LAMTOR2 domain A4G23_RS12910 a821b188aa3dd59dfe46daabd704a4c3 103 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 1 103 3.0E-38 T 10-11-2016 IPR024412 Lsr2 A4G23_RS12910 a821b188aa3dd59dfe46daabd704a4c3 103 Pfam PF11774 Lsr2 1 102 1.0E-34 T 10-11-2016 IPR024412 Lsr2 A4G23_RS19825 bf1eeb143c827a1f28c5d078406ea311 737 SUPERFAMILY SSF52540 168 247 1.11E-45 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS19825 bf1eeb143c827a1f28c5d078406ea311 737 SUPERFAMILY SSF52540 507 729 1.11E-45 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS19825 bf1eeb143c827a1f28c5d078406ea311 737 SUPERFAMILY SSF52540 346 405 1.11E-45 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS19825 bf1eeb143c827a1f28c5d078406ea311 737 Gene3D G3DSA:3.40.50.300 595 729 2.5E-18 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS19825 bf1eeb143c827a1f28c5d078406ea311 737 Pfam PF13538 UvrD-like helicase C-terminal domain 689 730 4.5E-9 T 10-11-2016 IPR027785 UvrD-like helicase C-terminal domain A4G23_RS19825 bf1eeb143c827a1f28c5d078406ea311 737 Pfam PF13245 Part of AAA domain 182 243 3.4E-16 T 10-11-2016 A4G23_RS19825 bf1eeb143c827a1f28c5d078406ea311 737 Gene3D G3DSA:3.40.50.300 169 277 2.6E-29 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS19825 bf1eeb143c827a1f28c5d078406ea311 737 Gene3D G3DSA:3.40.50.300 502 594 2.6E-29 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS14825 8bae6a5ebfb253ed805cc3351ee95fef 282 SUPERFAMILY SSF55811 25 78 1.93E-15 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS14825 8bae6a5ebfb253ed805cc3351ee95fef 282 SUPERFAMILY SSF55811 161 231 1.93E-15 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS14825 8bae6a5ebfb253ed805cc3351ee95fef 282 SUPERFAMILY SSF55811 105 116 1.93E-15 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS14825 8bae6a5ebfb253ed805cc3351ee95fef 282 Gene3D G3DSA:3.90.79.10 160 234 8.3E-18 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS14825 8bae6a5ebfb253ed805cc3351ee95fef 282 Gene3D G3DSA:3.90.79.10 27 115 8.3E-18 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS20760 4724b0f3cd7a7a6f46d5682191939f64 332 SUPERFAMILY SSF51197 8 309 2.7E-18 T 10-11-2016 A4G23_RS20760 4724b0f3cd7a7a6f46d5682191939f64 332 Gene3D G3DSA:3.60.130.10 9 309 9.7E-21 T 10-11-2016 A4G23_RS10575 01b12d16d3bdb4b0e6eb758a1262be7a 909 SUPERFAMILY SSF51621 16 909 1.27E-273 T 10-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A4G23_RS10575 01b12d16d3bdb4b0e6eb758a1262be7a 909 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 556 576 2.6E-57 T 10-11-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 A4G23_RS10575 01b12d16d3bdb4b0e6eb758a1262be7a 909 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 130 143 2.6E-57 T 10-11-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 A4G23_RS10575 01b12d16d3bdb4b0e6eb758a1262be7a 909 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 735 761 2.6E-57 T 10-11-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 A4G23_RS10575 01b12d16d3bdb4b0e6eb758a1262be7a 909 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 237 252 2.6E-57 T 10-11-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 A4G23_RS10575 01b12d16d3bdb4b0e6eb758a1262be7a 909 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 598 627 2.6E-57 T 10-11-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 A4G23_RS10575 01b12d16d3bdb4b0e6eb758a1262be7a 909 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 392 412 2.6E-57 T 10-11-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 A4G23_RS10575 01b12d16d3bdb4b0e6eb758a1262be7a 909 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 179 195 2.6E-57 T 10-11-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 A4G23_RS10575 01b12d16d3bdb4b0e6eb758a1262be7a 909 ProSitePatterns PS00393 Phosphoenolpyruvate carboxylase active site 2. 558 570 - T 10-11-2016 IPR033129 Phosphoenolpyruvate carboxylase, His active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 A4G23_RS10575 01b12d16d3bdb4b0e6eb758a1262be7a 909 Pfam PF00311 Phosphoenolpyruvate carboxylase 126 909 6.8E-286 T 10-11-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 A4G23_RS10575 01b12d16d3bdb4b0e6eb758a1262be7a 909 Hamap MF_00595 Phosphoenolpyruvate carboxylase [ppc]. 3 909 18.144 T 10-11-2016 IPR022805 Phosphoenolpyruvate carboxylase, bacterial/plant-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 A4G23_RS10575 01b12d16d3bdb4b0e6eb758a1262be7a 909 Gene3D G3DSA:1.20.1440.90 272 394 1.5E-24 T 10-11-2016 A4G23_RS10575 01b12d16d3bdb4b0e6eb758a1262be7a 909 ProSitePatterns PS00781 Phosphoenolpyruvate carboxylase active site 1. 131 142 - T 10-11-2016 IPR018129 Phosphoenolpyruvate carboxylase, Lys active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 A4G23_RS01630 326679a452af5d17675448984eb3bcde 207 SUPERFAMILY SSF55729 24 187 1.33E-33 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS01630 326679a452af5d17675448984eb3bcde 207 Pfam PF13302 Acetyltransferase (GNAT) domain 33 161 3.2E-20 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS01630 326679a452af5d17675448984eb3bcde 207 Gene3D G3DSA:3.40.630.30 24 192 1.7E-38 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS03145 18dc7fa4cec085b71f33231cbb154c80 220 SUPERFAMILY SSF55166 1 207 1.22E-58 T 10-11-2016 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 A4G23_RS03145 18dc7fa4cec085b71f33231cbb154c80 220 Hamap MF_01924 D-alanyl-D-alanine dipeptidase [ddpX]. 1 206 28.057 T 10-11-2016 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 A4G23_RS03145 18dc7fa4cec085b71f33231cbb154c80 220 Gene3D G3DSA:3.30.1380.10 1 207 2.3E-68 T 10-11-2016 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 A4G23_RS03145 18dc7fa4cec085b71f33231cbb154c80 220 Pfam PF01427 D-ala-D-ala dipeptidase 140 207 3.7E-14 T 10-11-2016 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 A4G23_RS03145 18dc7fa4cec085b71f33231cbb154c80 220 Pfam PF01427 D-ala-D-ala dipeptidase 2 109 8.0E-17 T 10-11-2016 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 A4G23_RS03145 18dc7fa4cec085b71f33231cbb154c80 220 PIRSF PIRSF026671 1 212 6.9E-67 T 10-11-2016 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 A4G23_RS25270 38947f3a26ee2571b684841942193c64 1295 Gene3D G3DSA:3.30.1490.20 126 206 2.8E-7 T 10-11-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A4G23_RS20985 4c05a7c626019fb9397e8e26f62fe6a5 500 PIRSF PIRSF017804 17 500 4.0E-138 T 10-11-2016 IPR006707 Type VII secretion system membrane protein EccD A4G23_RS20985 4c05a7c626019fb9397e8e26f62fe6a5 500 Pfam PF08817 WXG100 protein secretion system (Wss), protein YukD 25 99 5.0E-19 T 10-11-2016 IPR024962 YukD-like A4G23_RS20985 4c05a7c626019fb9397e8e26f62fe6a5 500 TIGRFAM TIGR03920 T7SS_EccD: type VII secretion integral membrane protein EccD 28 496 3.9E-51 T 10-11-2016 IPR006707 Type VII secretion system membrane protein EccD A4G23_RS15930 8c71f305b9b82928be67d06e08411211 2358 SUPERFAMILY SSF51294 2100 2242 3.27E-19 T 10-11-2016 IPR028992 Hedgehog/Intein (Hint) domain A4G23_RS15930 8c71f305b9b82928be67d06e08411211 2358 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1346 1382 5.8E-9 T 10-11-2016 IPR006530 YD repeat A4G23_RS15930 8c71f305b9b82928be67d06e08411211 2358 Pfam PF14428 SCP1.201-like deaminase 2274 2348 4.0E-9 T 10-11-2016 IPR032724 Deaminase, SCP1.201-like A4G23_RS15930 8c71f305b9b82928be67d06e08411211 2358 Pfam PF05593 RHS Repeat 1346 1380 2.8E-8 T 10-11-2016 IPR031325 RHS repeat A4G23_RS15930 8c71f305b9b82928be67d06e08411211 2358 SMART SM00306 2098 2199 2.8E-10 T 10-11-2016 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 A4G23_RS15930 8c71f305b9b82928be67d06e08411211 2358 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1864 1944 9.7E-15 T 10-11-2016 IPR022385 Rhs repeat-associated core GO:0097264 A4G23_RS15930 8c71f305b9b82928be67d06e08411211 2358 Gene3D G3DSA:2.170.16.10 2098 2244 1.1E-23 T 10-11-2016 IPR028992 Hedgehog/Intein (Hint) domain A4G23_RS15930 8c71f305b9b82928be67d06e08411211 2358 Pfam PF07591 Pretoxin HINT domain 2109 2242 1.4E-22 T 10-11-2016 A4G23_RS04295 28de84ce16f08e5df6f738996c2790a2 281 TIGRFAM TIGR03690 20S_bact_beta: proteasome, beta subunit 50 269 8.2E-119 T 10-11-2016 IPR022483 Peptidase T1A, proteasome beta-subunit, actinobacteria GO:0004298|GO:0005839|GO:0010498 A4G23_RS04295 28de84ce16f08e5df6f738996c2790a2 281 Pfam PF00227 Proteasome subunit 51 231 1.1E-38 T 10-11-2016 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5687128|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-983168 A4G23_RS04295 28de84ce16f08e5df6f738996c2790a2 281 SUPERFAMILY SSF56235 47 262 7.73E-60 T 10-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal A4G23_RS04295 28de84ce16f08e5df6f738996c2790a2 281 Gene3D G3DSA:3.60.20.10 54 259 3.7E-57 T 10-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal A4G23_RS04295 28de84ce16f08e5df6f738996c2790a2 281 Hamap MF_02113_B Proteasome subunit beta [prcB]. 7 275 50.965 T 10-11-2016 IPR022483 Peptidase T1A, proteasome beta-subunit, actinobacteria GO:0004298|GO:0005839|GO:0010498 A4G23_RS03220 12e88b03a18d5cbd1a236354890a69ae 472 SUPERFAMILY SSF48371 234 431 9.87E-8 T 10-11-2016 IPR016024 Armadillo-type fold GO:0005488 A4G23_RS04000 93ccb649951c70ba540d8983160d7afd 309 Hamap MF_00082_B Acetylglutamate kinase [argB]. 35 302 34.564 T 10-11-2016 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A4G23_RS04000 93ccb649951c70ba540d8983160d7afd 309 Gene3D G3DSA:3.40.1160.10 35 301 2.6E-98 T 10-11-2016 IPR001048 Aspartate/glutamate/uridylate kinase A4G23_RS04000 93ccb649951c70ba540d8983160d7afd 309 SUPERFAMILY SSF53633 16 304 5.89E-86 T 10-11-2016 IPR001048 Aspartate/glutamate/uridylate kinase A4G23_RS04000 93ccb649951c70ba540d8983160d7afd 309 PRINTS PR00474 Glutamate 5-kinase family signature 68 82 4.4E-9 T 10-11-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 A4G23_RS04000 93ccb649951c70ba540d8983160d7afd 309 PRINTS PR00474 Glutamate 5-kinase family signature 201 228 4.4E-9 T 10-11-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 A4G23_RS04000 93ccb649951c70ba540d8983160d7afd 309 PRINTS PR00474 Glutamate 5-kinase family signature 252 272 4.4E-9 T 10-11-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 A4G23_RS04000 93ccb649951c70ba540d8983160d7afd 309 Pfam PF00696 Amino acid kinase family 37 278 3.7E-48 T 10-11-2016 IPR001048 Aspartate/glutamate/uridylate kinase A4G23_RS04000 93ccb649951c70ba540d8983160d7afd 309 TIGRFAM TIGR00761 argB: acetylglutamate kinase 38 276 5.2E-73 T 10-11-2016 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A4G23_RS04000 93ccb649951c70ba540d8983160d7afd 309 PIRSF PIRSF000728 22 302 4.2E-97 T 10-11-2016 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A4G23_RS06290 075a35a29c1d22b1a9515698fd5824d9 339 Gene3D G3DSA:1.10.8.300 209 311 9.5E-34 T 10-11-2016 A4G23_RS06290 075a35a29c1d22b1a9515698fd5824d9 339 Gene3D G3DSA:3.40.50.300 33 193 3.6E-42 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS06290 075a35a29c1d22b1a9515698fd5824d9 339 PIRSF PIRSF002849 2 320 3.3E-126 T 10-11-2016 IPR016366 ATPase chaperone, AAA-type, MoxR, predicted A4G23_RS06290 075a35a29c1d22b1a9515698fd5824d9 339 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 47 176 5.1E-64 T 10-11-2016 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 A4G23_RS06290 075a35a29c1d22b1a9515698fd5824d9 339 SUPERFAMILY SSF52540 27 291 1.92E-42 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS18235 b60f0a445adcda049848a7ee2bb231e4 206 Gene3D G3DSA:2.40.380.10 1 187 2.7E-72 T 10-11-2016 IPR007295 Domain of unknown function DUF402 A4G23_RS18235 b60f0a445adcda049848a7ee2bb231e4 206 SUPERFAMILY SSF159234 19 188 2.35E-46 T 10-11-2016 A4G23_RS18235 b60f0a445adcda049848a7ee2bb231e4 206 Pfam PF04167 Protein of unknown function (DUF402) 76 140 1.0E-13 T 10-11-2016 IPR007295 Domain of unknown function DUF402 A4G23_RS09045 c06c1216ab26a115c0b690cbb9309cf7 203 Hamap MF_00045 Oligoribonuclease [orn]. 1 179 37.838 T 10-11-2016 IPR022894 Oligoribonuclease GO:0016788 A4G23_RS09045 c06c1216ab26a115c0b690cbb9309cf7 203 SMART SM00479 4 178 2.4E-25 T 10-11-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III A4G23_RS09045 c06c1216ab26a115c0b690cbb9309cf7 203 Gene3D G3DSA:3.30.420.10 1 177 4.2E-66 T 10-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 A4G23_RS09045 c06c1216ab26a115c0b690cbb9309cf7 203 Pfam PF00929 Exonuclease 6 168 2.6E-24 T 10-11-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III A4G23_RS09045 c06c1216ab26a115c0b690cbb9309cf7 203 SUPERFAMILY SSF53098 3 177 7.06E-41 T 10-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 A4G23_RS15970 83e180d4ba4ed6b7312d5f688eb17cf8 423 Gene3D G3DSA:3.30.2010.10 141 224 2.8E-11 T 10-11-2016 A4G23_RS15970 83e180d4ba4ed6b7312d5f688eb17cf8 423 Pfam PF01435 Peptidase family M48 143 378 1.0E-9 T 10-11-2016 IPR001915 Peptidase M48 GO:0004222|GO:0006508 A4G23_RS15025 2108d33624882cb7212e48f0c32a5fba 181 Pfam PF07884 Vitamin K epoxide reductase family 2 130 1.1E-30 T 10-11-2016 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 A4G23_RS15025 2108d33624882cb7212e48f0c32a5fba 181 SMART SM00756 1 136 6.9E-48 T 10-11-2016 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 A4G23_RS02500 c0b483d815b67aea6db9cb7dcfe0e3a0 317 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 38 280 1.0E-83 T 10-11-2016 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related A4G23_RS11275 b6e6a755ddce5c2c9c63d1bb05c66c23 286 Pfam PF01061 ABC-2 type transporter 46 252 4.8E-33 T 10-11-2016 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A4G23_RS11275 b6e6a755ddce5c2c9c63d1bb05c66c23 286 PIRSF PIRSF006648 19 286 5.3E-71 T 10-11-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 A4G23_RS00845 aaea83967cdc49e60e1ecd70b8c8260d 333 Gene3D G3DSA:3.10.310.10 1 155 2.7E-68 T 10-11-2016 A4G23_RS00845 aaea83967cdc49e60e1ecd70b8c8260d 333 Gene3D G3DSA:3.10.310.10 156 320 3.3E-64 T 10-11-2016 A4G23_RS00845 aaea83967cdc49e60e1ecd70b8c8260d 333 Pfam PF05544 Proline racemase 10 332 1.2E-137 T 10-11-2016 IPR008794 Proline racemase family A4G23_RS00845 aaea83967cdc49e60e1ecd70b8c8260d 333 PIRSF PIRSF029792 1 333 7.3E-132 T 10-11-2016 IPR008794 Proline racemase family A4G23_RS00845 aaea83967cdc49e60e1ecd70b8c8260d 333 SUPERFAMILY SSF54506 1 331 2.22E-121 T 10-11-2016 A4G23_RS18685 b6d484cde9aec6e639e2acf7cb7bb0f9 437 SUPERFAMILY SSF55486 290 419 1.63E-11 T 10-11-2016 A4G23_RS18685 b6d484cde9aec6e639e2acf7cb7bb0f9 437 Pfam PF11350 Protein of unknown function (DUF3152) 254 435 5.7E-56 T 10-11-2016 IPR022603 Domain of unknown function DUF3152 A4G23_RS20065 55b9fc94ba3f3722d66c83260cca0941 705 SUPERFAMILY SSF55073 267 418 1.65E-42 T 10-11-2016 IPR029787 Nucleotide cyclase A4G23_RS20065 55b9fc94ba3f3722d66c83260cca0941 705 SMART SM00267 256 422 4.9E-47 T 10-11-2016 IPR000160 GGDEF domain A4G23_RS20065 55b9fc94ba3f3722d66c83260cca0941 705 Gene3D G3DSA:3.30.70.270 264 425 6.5E-50 T 10-11-2016 A4G23_RS20065 55b9fc94ba3f3722d66c83260cca0941 705 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 262 416 1.9E-34 T 10-11-2016 IPR000160 GGDEF domain A4G23_RS20065 55b9fc94ba3f3722d66c83260cca0941 705 Pfam PF00563 EAL domain 439 669 2.6E-71 T 10-11-2016 IPR001633 EAL domain A4G23_RS20065 55b9fc94ba3f3722d66c83260cca0941 705 Gene3D G3DSA:3.20.20.450 438 683 5.7E-92 T 10-11-2016 IPR001633 EAL domain A4G23_RS20065 55b9fc94ba3f3722d66c83260cca0941 705 SUPERFAMILY SSF141868 438 684 3.27E-83 T 10-11-2016 IPR001633 EAL domain A4G23_RS20065 55b9fc94ba3f3722d66c83260cca0941 705 Pfam PF00990 Diguanylate cyclase, GGDEF domain 264 416 7.9E-40 T 10-11-2016 IPR000160 GGDEF domain A4G23_RS20065 55b9fc94ba3f3722d66c83260cca0941 705 SMART SM00052 432 676 7.1E-103 T 10-11-2016 IPR001633 EAL domain A4G23_RS13985 e2c0c7d9aab55ed85781aa66a4151857 214 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 93 183 3.5E-15 T 10-11-2016 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain A4G23_RS01925 72d43b54e27993a2d65d92386d0a6aab 237 SUPERFAMILY SSF46955 124 232 5.95E-16 T 10-11-2016 IPR009061 Putative DNA-binding domain A4G23_RS01925 72d43b54e27993a2d65d92386d0a6aab 237 Gene3D G3DSA:1.10.1660.10 8 108 3.2E-16 T 10-11-2016 A4G23_RS01925 72d43b54e27993a2d65d92386d0a6aab 237 Gene3D G3DSA:1.10.1660.10 124 234 1.4E-17 T 10-11-2016 A4G23_RS01925 72d43b54e27993a2d65d92386d0a6aab 237 Pfam PF00376 MerR family regulatory protein 9 43 2.2E-9 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS01925 72d43b54e27993a2d65d92386d0a6aab 237 SMART SM00422 5 73 1.3E-4 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS01925 72d43b54e27993a2d65d92386d0a6aab 237 SMART SM00422 124 193 7.8E-5 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS01925 72d43b54e27993a2d65d92386d0a6aab 237 Pfam PF13411 MerR HTH family regulatory protein 125 191 1.5E-13 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS01925 72d43b54e27993a2d65d92386d0a6aab 237 ProSitePatterns PS00552 MerR-type HTH domain signature. 127 149 - T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS01925 72d43b54e27993a2d65d92386d0a6aab 237 SUPERFAMILY SSF46955 8 107 5.49E-14 T 10-11-2016 IPR009061 Putative DNA-binding domain A4G23_RS12535 b43e9c180ea17c65bd3ad8c73f2a6d02 362 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 88 354 1.5E-83 T 10-11-2016 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 A4G23_RS12535 b43e9c180ea17c65bd3ad8c73f2a6d02 362 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 161 360 1.6E-24 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS12535 b43e9c180ea17c65bd3ad8c73f2a6d02 362 Gene3D G3DSA:1.10.3720.10 86 356 1.2E-42 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS12535 b43e9c180ea17c65bd3ad8c73f2a6d02 362 SUPERFAMILY SSF161098 95 349 7.33E-40 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS18330 d039ff1d4e8d5c1c2b7ab321c8741822 87 SUPERFAMILY SSF143011 4 83 1.12E-19 T 10-11-2016 A4G23_RS18330 d039ff1d4e8d5c1c2b7ab321c8741822 87 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 8 85 5.4E-13 T 10-11-2016 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family A4G23_RS16175 d7b8aba9f8f19759b96eba2de5e32587 443 Pfam PF07730 Histidine kinase 255 319 1.2E-12 T 10-11-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4G23_RS16175 d7b8aba9f8f19759b96eba2de5e32587 443 SUPERFAMILY SSF55874 353 440 2.1E-13 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS16175 d7b8aba9f8f19759b96eba2de5e32587 443 Gene3D G3DSA:3.30.565.10 361 441 5.0E-5 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS16175 d7b8aba9f8f19759b96eba2de5e32587 443 Pfam PF13796 Putative sensor 38 227 2.0E-41 T 10-11-2016 IPR025828 Putative sensor domain A4G23_RS25770 60eac650c1a664b2943aab415900fe24 310 Pfam PF01522 Polysaccharide deacetylase 125 242 9.4E-33 T 10-11-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 A4G23_RS25770 60eac650c1a664b2943aab415900fe24 310 SUPERFAMILY SSF88713 117 305 8.23E-57 T 10-11-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A4G23_RS25770 60eac650c1a664b2943aab415900fe24 310 Gene3D G3DSA:3.20.20.370 122 305 7.5E-56 T 10-11-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 A4G23_RS17515 ff40087444e671c1acbade65f485f8f2 206 SUPERFAMILY SSF141523 92 204 5.62E-20 T 10-11-2016 A4G23_RS17515 ff40087444e671c1acbade65f485f8f2 206 Pfam PF03734 L,D-transpeptidase catalytic domain 93 204 2.7E-15 T 10-11-2016 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 A4G23_RS17515 ff40087444e671c1acbade65f485f8f2 206 Pfam PF01471 Putative peptidoglycan binding domain 7 62 6.6E-15 T 10-11-2016 IPR002477 Peptidoglycan binding-like A4G23_RS17515 ff40087444e671c1acbade65f485f8f2 206 SUPERFAMILY SSF47090 3 66 5.97E-17 T 10-11-2016 IPR002477 Peptidoglycan binding-like A4G23_RS17515 ff40087444e671c1acbade65f485f8f2 206 Gene3D G3DSA:2.40.440.10 93 204 6.7E-16 T 10-11-2016 A4G23_RS17515 ff40087444e671c1acbade65f485f8f2 206 Gene3D G3DSA:1.10.101.10 2 66 6.2E-17 T 10-11-2016 IPR002477 Peptidoglycan binding-like A4G23_RS18965 e8f3494fcdc8cb78744ae3f4dd623e3a 337 Gene3D G3DSA:1.10.620.20 16 304 3.4E-95 T 10-11-2016 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: R-HSA-499943 A4G23_RS18965 e8f3494fcdc8cb78744ae3f4dd623e3a 337 SUPERFAMILY SSF47240 17 336 4.99E-87 T 10-11-2016 IPR009078 Ferritin-like superfamily A4G23_RS18965 e8f3494fcdc8cb78744ae3f4dd623e3a 337 Pfam PF00268 Ribonucleotide reductase, small chain 16 300 1.9E-78 T 10-11-2016 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4G23_RS18965 e8f3494fcdc8cb78744ae3f4dd623e3a 337 PIRSF PIRSF000355 8 335 3.5E-96 T 10-11-2016 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4G23_RS06025 1f1387dc3a52cc0064a155b8155abd64 116 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 9 112 31.597 T 10-11-2016 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 A4G23_RS06025 1f1387dc3a52cc0064a155b8155abd64 116 SUPERFAMILY SSF141734 8 111 1.14E-46 T 10-11-2016 A4G23_RS06025 1f1387dc3a52cc0064a155b8155abd64 116 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 58 112 5.0E-23 T 10-11-2016 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 A4G23_RS06025 1f1387dc3a52cc0064a155b8155abd64 116 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 35 107 1.1E-33 T 10-11-2016 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 A4G23_RS26360 7883481cf84459edf642810f43fd8d6c 227 TIGRFAM TIGR00537 hemK_rel_arch: putative methylase 20 195 2.3E-34 T 10-11-2016 IPR004557 Eukaryotic/archaeal PrmC-related GO:0008276 Reactome: R-HSA-156581|Reactome: R-HSA-72764 A4G23_RS26360 7883481cf84459edf642810f43fd8d6c 227 SUPERFAMILY SSF53335 11 188 2.54E-36 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS26360 7883481cf84459edf642810f43fd8d6c 227 Gene3D G3DSA:3.40.50.150 17 187 2.6E-42 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS26360 7883481cf84459edf642810f43fd8d6c 227 Pfam PF05175 Methyltransferase small domain 27 115 4.1E-14 T 10-11-2016 IPR007848 Methyltransferase small domain GO:0008168 A4G23_RS26360 7883481cf84459edf642810f43fd8d6c 227 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 109 115 - T 10-11-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A4G23_RS20925 3f09e4dea403407c011c5373aab17920 1175 Pfam PF13614 AAA domain 751 897 1.5E-10 T 10-11-2016 IPR025669 AAA domain A4G23_RS20925 3f09e4dea403407c011c5373aab17920 1175 SUPERFAMILY SSF52540 749 988 1.66E-25 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS20925 3f09e4dea403407c011c5373aab17920 1175 Gene3D G3DSA:3.40.50.300 750 987 1.5E-27 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS25775 c9b6d8fbbf48c57b29ec31ea42f90703 225 SUPERFAMILY SSF63817 80 223 5.49E-16 T 10-11-2016 IPR023365 Sortase domain A4G23_RS25775 c9b6d8fbbf48c57b29ec31ea42f90703 225 Gene3D G3DSA:2.40.260.10 81 222 3.5E-6 T 10-11-2016 IPR023365 Sortase domain A4G23_RS25775 c9b6d8fbbf48c57b29ec31ea42f90703 225 Pfam PF04203 Sortase family 82 222 7.0E-17 T 10-11-2016 IPR005754 Sortase family A4G23_RS22620 d148f4a9b73fdbc4c331e896edb517fb 389 SUPERFAMILY SSF53474 221 386 1.01E-7 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS22620 d148f4a9b73fdbc4c331e896edb517fb 389 Gene3D G3DSA:3.40.50.1820 244 330 2.3E-6 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS19160 f6694075358602aba220336f04baafd4 94 Gene3D G3DSA:1.10.10.10 10 82 4.5E-20 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS19160 f6694075358602aba220336f04baafd4 94 SUPERFAMILY SSF46785 8 82 6.22E-16 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS19160 f6694075358602aba220336f04baafd4 94 SMART SM00345 20 79 7.1E-7 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS19160 f6694075358602aba220336f04baafd4 94 Pfam PF00392 Bacterial regulatory proteins, gntR family 18 79 1.2E-10 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS22880 c5ac505b87d306314697002e47dcf252 264 Gene3D G3DSA:3.40.50.300 7 238 2.0E-64 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS22880 c5ac505b87d306314697002e47dcf252 264 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS22880 c5ac505b87d306314697002e47dcf252 264 Pfam PF00005 ABC transporter 25 175 3.0E-31 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS22880 c5ac505b87d306314697002e47dcf252 264 SMART SM00382 34 223 6.7E-11 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS22880 c5ac505b87d306314697002e47dcf252 264 SUPERFAMILY SSF52540 8 230 3.37E-59 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS07240 5ddb5ea4d7c1f192f649cd745cfe8bb6 218 Pfam PF07510 Protein of unknown function (DUF1524) 118 211 1.5E-10 T 10-11-2016 IPR011089 Domain of unknown function DUF1524 A4G23_RS06760 229869cbf7122e605b89d9289ba0810b 235 Pfam PF13829 Domain of unknown function (DUF4191) 14 230 1.0E-84 T 10-11-2016 IPR025445 Protein of unknown function DUF4191 A4G23_RS06760 229869cbf7122e605b89d9289ba0810b 235 ProDom PD037701 MEMBRANE INTEGRAL TRANSMEMBRANE RV2219/MT2276 NARROWLY PROBABLE PRECURSOR SIGNAL MLCB22.21 1 217 7.0E-67 T 10-11-2016 A4G23_RS02570 4607a54fc25f6d1ee4eae3c22c22e2da 381 SUPERFAMILY SSF53383 30 374 2.82E-93 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS02570 4607a54fc25f6d1ee4eae3c22c22e2da 381 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 229 238 - T 10-11-2016 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 A4G23_RS02570 4607a54fc25f6d1ee4eae3c22c22e2da 381 Gene3D G3DSA:3.40.640.10 51 265 6.7E-80 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS02570 4607a54fc25f6d1ee4eae3c22c22e2da 381 Gene3D G3DSA:3.90.1150.10 266 374 2.5E-16 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS02570 4607a54fc25f6d1ee4eae3c22c22e2da 381 Pfam PF00155 Aminotransferase class I and II 33 373 7.5E-57 T 10-11-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4G23_RS19690 428f46adc61d3f729a8e3fa0d1200413 318 Pfam PF03308 ArgK protein 20 280 9.5E-100 T 10-11-2016 A4G23_RS19690 428f46adc61d3f729a8e3fa0d1200413 318 SUPERFAMILY SSF52540 3 312 1.93E-78 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS19690 428f46adc61d3f729a8e3fa0d1200413 318 Gene3D G3DSA:3.40.50.300 46 251 3.2E-51 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS19690 428f46adc61d3f729a8e3fa0d1200413 318 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 15 312 2.3E-107 T 10-11-2016 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A4G23_RS08875 35762f62b3c9106025d8381ed5faf918 124 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 15 117 2.6E-4 T 10-11-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4G23_RS08875 35762f62b3c9106025d8381ed5faf918 124 Gene3D G3DSA:3.10.180.10 7 123 3.0E-18 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS08875 35762f62b3c9106025d8381ed5faf918 124 SUPERFAMILY SSF54593 8 123 2.82E-18 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS06020 901ae69fb5e27258db72c87be1f65f23 504 Pfam PF00425 chorismate binding enzyme 235 487 2.7E-98 T 10-11-2016 IPR015890 Chorismate-utilising enzyme, C-terminal A4G23_RS06020 901ae69fb5e27258db72c87be1f65f23 504 Pfam PF04715 Anthranilate synthase component I, N terminal region 26 176 8.6E-30 T 10-11-2016 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058|GO:0016833 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A4G23_RS06020 901ae69fb5e27258db72c87be1f65f23 504 PRINTS PR00095 Anthranilate synthase component I signature 335 348 1.5E-23 T 10-11-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A4G23_RS06020 901ae69fb5e27258db72c87be1f65f23 504 PRINTS PR00095 Anthranilate synthase component I signature 444 458 1.5E-23 T 10-11-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A4G23_RS06020 901ae69fb5e27258db72c87be1f65f23 504 PRINTS PR00095 Anthranilate synthase component I signature 349 362 1.5E-23 T 10-11-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A4G23_RS06020 901ae69fb5e27258db72c87be1f65f23 504 PRINTS PR00095 Anthranilate synthase component I signature 429 443 1.5E-23 T 10-11-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A4G23_RS06020 901ae69fb5e27258db72c87be1f65f23 504 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 25 496 2.7E-172 T 10-11-2016 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A4G23_RS06020 901ae69fb5e27258db72c87be1f65f23 504 Gene3D G3DSA:3.60.120.10 13 499 2.8E-174 T 10-11-2016 IPR005801 ADC synthase GO:0009058 A4G23_RS06020 901ae69fb5e27258db72c87be1f65f23 504 SUPERFAMILY SSF56322 14 496 6.54E-157 T 10-11-2016 IPR005801 ADC synthase GO:0009058 A4G23_RS23220 fb1875f9b8e9c2de6a132ef88aa47906 400 Pfam PF03631 Virulence factor BrkB 74 327 2.5E-45 T 10-11-2016 IPR017039 Virulence factor BrkB A4G23_RS13740 9e35b2869283cfa1a09c6cbdf5181d04 180 Pfam PF01885 RNA 2'-phosphotransferase, Tpt1 / KptA family 5 169 3.0E-43 T 10-11-2016 IPR002745 Phosphotransferase KptA/Tpt1 GO:0006388|GO:0016772 A4G23_RS13740 9e35b2869283cfa1a09c6cbdf5181d04 180 SUPERFAMILY SSF56399 7 177 3.16E-62 T 10-11-2016 A4G23_RS13740 9e35b2869283cfa1a09c6cbdf5181d04 180 Hamap MF_00299 Probable RNA 2'-phosphotransferase [kptA]. 5 176 34.814 T 10-11-2016 IPR022928 RNA 2'-phosphotransferase KptA, putative GO:0016773 A4G23_RS13310 f047a01ad3e13859ff180bcb3a34b266 309 SUPERFAMILY SSF46565 165 205 2.36E-5 T 10-11-2016 IPR001623 DnaJ domain A4G23_RS13310 f047a01ad3e13859ff180bcb3a34b266 309 Gene3D G3DSA:1.10.287.110 167 205 2.7E-5 T 10-11-2016 IPR001623 DnaJ domain A4G23_RS24065 0d0039ebcdea622aa2f7ae87f7747234 259 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 257 3.4E-78 T 10-11-2016 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 A4G23_RS24065 0d0039ebcdea622aa2f7ae87f7747234 259 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 256 1.8E-57 T 10-11-2016 A4G23_RS24065 0d0039ebcdea622aa2f7ae87f7747234 259 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 250 1.1E-21 T 10-11-2016 IPR005135 Endonuclease/exonuclease/phosphatase A4G23_RS24065 0d0039ebcdea622aa2f7ae87f7747234 259 Gene3D G3DSA:3.60.10.10 1 258 4.8E-77 T 10-11-2016 IPR005135 Endonuclease/exonuclease/phosphatase A4G23_RS24065 0d0039ebcdea622aa2f7ae87f7747234 259 SUPERFAMILY SSF56219 1 258 1.24E-68 T 10-11-2016 IPR005135 Endonuclease/exonuclease/phosphatase A4G23_RS14950 078ca1966cc39f25cb9aa1ecd22952e4 798 TIGRFAM TIGR01104 V_PPase: V-type H(+)-translocating pyrophosphatase 31 741 8.9E-203 T 10-11-2016 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1 A4G23_RS14950 078ca1966cc39f25cb9aa1ecd22952e4 798 Hamap MF_01129 Putative K(+)-stimulated pyrophosphate-energized sodium pump [hppA]. 26 740 24.478 T 10-11-2016 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1 A4G23_RS14950 078ca1966cc39f25cb9aa1ecd22952e4 798 PIRSF PIRSF001265 21 747 1.4E-259 T 10-11-2016 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1 A4G23_RS14950 078ca1966cc39f25cb9aa1ecd22952e4 798 Pfam PF03030 Inorganic H+ pyrophosphatase 37 735 1.4E-236 T 10-11-2016 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1 A4G23_RS22610 6e1b95a78220d8b477b33e1209e5021f 921 Pfam PF13191 AAA ATPase domain 194 405 1.9E-11 T 10-11-2016 A4G23_RS22610 6e1b95a78220d8b477b33e1209e5021f 921 SUPERFAMILY SSF52540 366 491 1.83E-10 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS22610 6e1b95a78220d8b477b33e1209e5021f 921 SUPERFAMILY SSF52540 271 301 1.83E-10 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS22610 6e1b95a78220d8b477b33e1209e5021f 921 SUPERFAMILY SSF52540 193 243 1.83E-10 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS22610 6e1b95a78220d8b477b33e1209e5021f 921 Gene3D G3DSA:3.40.50.300 195 427 1.1E-6 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS21895 5a6ee9bab224e8f934e69d3114166e1a 145 Gene3D G3DSA:2.40.50.140 81 140 8.1E-23 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS21895 5a6ee9bab224e8f934e69d3114166e1a 145 SUPERFAMILY SSF141322 79 138 6.67E-7 T 10-11-2016 A4G23_RS21895 5a6ee9bab224e8f934e69d3114166e1a 145 Pfam PF01957 NfeD-like C-terminal, partner-binding 5 140 2.9E-17 T 10-11-2016 IPR002810 NfeD-like, C-terminal domain A4G23_RS20260 e00d12f55e2923b409d87cea2a98fbdb 137 SMART SM00960 9 99 3.4E-33 T 10-11-2016 IPR004942 Roadblock/LAMTOR2 domain A4G23_RS20260 e00d12f55e2923b409d87cea2a98fbdb 137 Gene3D G3DSA:3.30.450.30 3 123 3.7E-25 T 10-11-2016 A4G23_RS20260 e00d12f55e2923b409d87cea2a98fbdb 137 SUPERFAMILY SSF103196 2 125 5.36E-32 T 10-11-2016 A4G23_RS20260 e00d12f55e2923b409d87cea2a98fbdb 137 Pfam PF03259 Roadblock/LC7 domain 9 99 1.5E-25 T 10-11-2016 IPR004942 Roadblock/LAMTOR2 domain A4G23_RS13565 cbb008ae8e897a79d9b9d95c62705038 230 Pfam PF03551 Transcriptional regulator PadR-like family 12 94 4.0E-14 T 10-11-2016 IPR005149 Transcription regulator PadR, N-terminal A4G23_RS13565 cbb008ae8e897a79d9b9d95c62705038 230 Gene3D G3DSA:1.10.10.10 4 99 1.6E-29 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS13565 cbb008ae8e897a79d9b9d95c62705038 230 SUPERFAMILY SSF46785 8 184 1.44E-33 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS05240 a66214dfe8c2aa38da17a5d43bcabf5c 251 SUPERFAMILY SSF51735 1 247 1.11E-59 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS05240 a66214dfe8c2aa38da17a5d43bcabf5c 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 247 6.0E-45 T 10-11-2016 A4G23_RS05240 a66214dfe8c2aa38da17a5d43bcabf5c 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 1.4E-17 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS05240 a66214dfe8c2aa38da17a5d43bcabf5c 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.4E-17 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS05240 a66214dfe8c2aa38da17a5d43bcabf5c 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 1.4E-17 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS05240 a66214dfe8c2aa38da17a5d43bcabf5c 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 1.4E-17 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS05240 a66214dfe8c2aa38da17a5d43bcabf5c 251 Gene3D G3DSA:3.40.50.720 1 246 1.7E-59 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS09770 e10525e24d1b15b1db6d13632880a30f 464 SUPERFAMILY SSF160964 39 97 1.96E-6 T 10-11-2016 A4G23_RS09770 e10525e24d1b15b1db6d13632880a30f 464 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 320 451 3.6E-18 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS09770 e10525e24d1b15b1db6d13632880a30f 464 SUPERFAMILY SSF161098 316 452 1.38E-43 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS09770 e10525e24d1b15b1db6d13632880a30f 464 SUPERFAMILY SSF161098 84 174 1.38E-43 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS09770 e10525e24d1b15b1db6d13632880a30f 464 Gene3D G3DSA:1.10.3720.10 319 455 4.1E-66 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS09770 e10525e24d1b15b1db6d13632880a30f 464 Gene3D G3DSA:1.10.3720.10 43 167 4.1E-66 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS07220 38db4d9635db845591bae413bceb78e8 682 SUPERFAMILY SSF103473 261 432 1.14E-70 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS07220 38db4d9635db845591bae413bceb78e8 682 SUPERFAMILY SSF103473 27 214 1.14E-70 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS07220 38db4d9635db845591bae413bceb78e8 682 SUPERFAMILY SSF103473 480 507 1.14E-70 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS07220 38db4d9635db845591bae413bceb78e8 682 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 27 497 2.9E-81 T 10-11-2016 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 A4G23_RS07220 38db4d9635db845591bae413bceb78e8 682 Gene3D G3DSA:1.10.10.10 560 663 1.0E-6 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS07220 38db4d9635db845591bae413bceb78e8 682 Gene3D G3DSA:1.20.1250.20 275 430 3.4E-19 T 10-11-2016 A4G23_RS07220 38db4d9635db845591bae413bceb78e8 682 Gene3D G3DSA:1.20.1250.20 27 204 2.9E-35 T 10-11-2016 A4G23_RS07220 38db4d9635db845591bae413bceb78e8 682 Gene3D G3DSA:1.20.1250.20 476 508 3.4E-19 T 10-11-2016 A4G23_RS07220 38db4d9635db845591bae413bceb78e8 682 PRINTS PR01036 Tetracycline resistance protein TetB signature 413 432 1.2E-6 T 10-11-2016 A4G23_RS07220 38db4d9635db845591bae413bceb78e8 682 PRINTS PR01036 Tetracycline resistance protein TetB signature 314 338 1.2E-6 T 10-11-2016 A4G23_RS07220 38db4d9635db845591bae413bceb78e8 682 PRINTS PR01036 Tetracycline resistance protein TetB signature 29 53 1.2E-6 T 10-11-2016 A4G23_RS07220 38db4d9635db845591bae413bceb78e8 682 PRINTS PR01036 Tetracycline resistance protein TetB signature 149 173 1.2E-6 T 10-11-2016 A4G23_RS07220 38db4d9635db845591bae413bceb78e8 682 PRINTS PR01036 Tetracycline resistance protein TetB signature 119 139 1.2E-6 T 10-11-2016 A4G23_RS07220 38db4d9635db845591bae413bceb78e8 682 SUPERFAMILY SSF46785 560 660 2.97E-7 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS07220 38db4d9635db845591bae413bceb78e8 682 Pfam PF07690 Major Facilitator Superfamily 30 422 5.5E-54 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS20255 abbdb9916b10d06eb62f7290489ce84c 136 Pfam PF05331 Protein of unknown function (DUF742) 25 136 6.8E-41 T 10-11-2016 IPR007995 Protein of unknown function DUF742 A4G23_RS04270 fbb78652abe14b7c46b8ff4009f22768 329 Gene3D G3DSA:3.10.50.40 60 191 1.8E-25 T 10-11-2016 A4G23_RS04270 fbb78652abe14b7c46b8ff4009f22768 329 Gene3D G3DSA:3.10.50.40 214 326 5.9E-31 T 10-11-2016 A4G23_RS04270 fbb78652abe14b7c46b8ff4009f22768 329 SUPERFAMILY SSF54534 68 180 1.06E-24 T 10-11-2016 A4G23_RS04270 fbb78652abe14b7c46b8ff4009f22768 329 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 240 325 3.0E-19 T 10-11-2016 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 A4G23_RS04270 fbb78652abe14b7c46b8ff4009f22768 329 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 93 180 4.1E-16 T 10-11-2016 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 A4G23_RS04270 fbb78652abe14b7c46b8ff4009f22768 329 SUPERFAMILY SSF54534 219 326 4.52E-32 T 10-11-2016 A4G23_RS21650 fee102bb6e832ddd99acc1932f6019e9 262 Pfam PF00975 Thioesterase domain 25 249 4.8E-29 T 10-11-2016 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 A4G23_RS21650 fee102bb6e832ddd99acc1932f6019e9 262 Gene3D G3DSA:3.40.50.1820 18 253 5.0E-27 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS21650 fee102bb6e832ddd99acc1932f6019e9 262 SUPERFAMILY SSF53474 18 249 1.46E-36 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS13715 390121aabc0d58a83c70bb50d98cdcb4 333 PIRSF PIRSF000267 1 333 3.1E-123 T 10-11-2016 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 A4G23_RS13715 390121aabc0d58a83c70bb50d98cdcb4 333 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 3 215 2.3E-76 T 10-11-2016 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 A4G23_RS13715 390121aabc0d58a83c70bb50d98cdcb4 333 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 3 320 1.2E-114 T 10-11-2016 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 A4G23_RS13510 fef6772b3db34f017ab1937916316d7e 205 Pfam PF00583 Acetyltransferase (GNAT) family 65 139 4.0E-9 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS13510 fef6772b3db34f017ab1937916316d7e 205 Gene3D G3DSA:3.40.630.30 5 135 9.4E-12 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS13510 fef6772b3db34f017ab1937916316d7e 205 SUPERFAMILY SSF55729 29 140 5.32E-13 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS18535 fe378c951ceda5b13d84dc586db353a0 114 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 48 80 2.4E-9 T 10-11-2016 IPR019933 DivIVA domain A4G23_RS14410 52d6cd2bc8876ef3060bd4e40a294b00 148 Pfam PF02397 Bacterial sugar transferase 2 146 1.6E-18 T 10-11-2016 IPR003362 Bacterial sugar transferase A4G23_RS24755 c48c14c05b1d9f04dcb628de7df99d53 248 Pfam PF13411 MerR HTH family regulatory protein 11 79 6.3E-20 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS24755 c48c14c05b1d9f04dcb628de7df99d53 248 Gene3D G3DSA:1.10.1660.10 11 82 1.4E-19 T 10-11-2016 A4G23_RS24755 c48c14c05b1d9f04dcb628de7df99d53 248 SUPERFAMILY SSF46955 11 86 1.79E-18 T 10-11-2016 IPR009061 Putative DNA-binding domain A4G23_RS24755 c48c14c05b1d9f04dcb628de7df99d53 248 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 23 36 7.3E-10 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS24755 c48c14c05b1d9f04dcb628de7df99d53 248 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 12 23 7.3E-10 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS24755 c48c14c05b1d9f04dcb628de7df99d53 248 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 47 67 7.3E-10 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS24755 c48c14c05b1d9f04dcb628de7df99d53 248 SMART SM00422 11 80 1.2E-22 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS14495 0c975a1d24308812cdfee78ad841ba5c 387 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 10 138 5.2E-11 T 10-11-2016 IPR010419 Carbon monoxide dehydrogenase subunit G A4G23_RS14495 0c975a1d24308812cdfee78ad841ba5c 387 SUPERFAMILY SSF55961 2 137 8.24E-19 T 10-11-2016 A4G23_RS14495 0c975a1d24308812cdfee78ad841ba5c 387 Gene3D G3DSA:3.30.530.20 2 139 2.4E-24 T 10-11-2016 IPR023393 START-like domain A4G23_RS09160 cfb9ce23f49be3a5d3ef5bfeee4cda8e 335 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 121 318 1.8E-12 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS09160 cfb9ce23f49be3a5d3ef5bfeee4cda8e 335 Gene3D G3DSA:1.10.3720.10 95 318 1.1E-56 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS09160 cfb9ce23f49be3a5d3ef5bfeee4cda8e 335 SUPERFAMILY SSF161098 89 318 4.45E-59 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS04590 c63c3d821cf51816c3d3461442ea6a7f 218 SUPERFAMILY SSF46689 17 97 4.41E-18 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS04590 c63c3d821cf51816c3d3461442ea6a7f 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 3.9E-10 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS04590 c63c3d821cf51816c3d3461442ea6a7f 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 3.9E-10 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS04590 c63c3d821cf51816c3d3461442ea6a7f 218 SUPERFAMILY SSF48498 92 205 1.55E-17 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS04590 c63c3d821cf51816c3d3461442ea6a7f 218 Gene3D G3DSA:1.10.357.10 67 206 1.2E-34 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS04590 c63c3d821cf51816c3d3461442ea6a7f 218 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 70 9.6E-18 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS04590 c63c3d821cf51816c3d3461442ea6a7f 218 Gene3D G3DSA:1.10.10.60 20 66 7.6E-19 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS04155 e557c5540528480fc82367bba6d6aa9b 334 PRINTS PR01217 Proline rich extensin signature 40 61 9.6E-11 T 10-11-2016 A4G23_RS04155 e557c5540528480fc82367bba6d6aa9b 334 PRINTS PR01217 Proline rich extensin signature 2 14 9.6E-11 T 10-11-2016 A4G23_RS04155 e557c5540528480fc82367bba6d6aa9b 334 PRINTS PR01217 Proline rich extensin signature 119 144 9.6E-11 T 10-11-2016 A4G23_RS04155 e557c5540528480fc82367bba6d6aa9b 334 PRINTS PR01217 Proline rich extensin signature 95 112 9.6E-11 T 10-11-2016 A4G23_RS04155 e557c5540528480fc82367bba6d6aa9b 334 Pfam PF10708 Protein of unknown function (DUF2510) 5 37 3.4E-11 T 10-11-2016 IPR018929 Domain of unknown function DUF2510 A4G23_RS10360 e2207037c3027696b1c93f9065bc61cc 90 SUPERFAMILY SSF143120 4 68 2.75E-13 T 10-11-2016 A4G23_RS10360 e2207037c3027696b1c93f9065bc61cc 90 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 5 52 2.2E-14 T 10-11-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM A4G23_RS10360 e2207037c3027696b1c93f9065bc61cc 90 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 4 72 1.5E-17 T 10-11-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM A4G23_RS10360 e2207037c3027696b1c93f9065bc61cc 90 Gene3D G3DSA:3.40.1620.10 3 52 2.8E-23 T 10-11-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM A4G23_RS23475 d445227f08324ccc0e23fe629f3a3b82 57 SUPERFAMILY SSF69047 6 56 1.15E-7 T 10-11-2016 IPR008462 CsbD-like A4G23_RS23475 d445227f08324ccc0e23fe629f3a3b82 57 Pfam PF05532 CsbD-like 6 57 6.2E-17 T 10-11-2016 IPR008462 CsbD-like A4G23_RS23475 d445227f08324ccc0e23fe629f3a3b82 57 Gene3D G3DSA:1.10.1470.10 4 57 3.0E-11 T 10-11-2016 IPR008462 CsbD-like A4G23_RS13450 7a32e8352243d0623148c22c1fbff39d 209 Hamap MF_00630 UPF0232 protein . 8 195 29.897 T 10-11-2016 IPR023007 Uncharacterised protein family UPF0232, actinobacteria A4G23_RS13450 7a32e8352243d0623148c22c1fbff39d 209 Pfam PF05258 Protein of unknown function (DUF721) 92 183 2.0E-26 T 10-11-2016 IPR007922 Protein of unknown function DUF721/UPF0232 A4G23_RS24530 fd8741370be289d7ef65410cf3e30208 284 SUPERFAMILY SSF53335 21 275 2.37E-31 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS24530 fd8741370be289d7ef65410cf3e30208 284 Pfam PF13649 Methyltransferase domain 47 141 5.0E-13 T 10-11-2016 A4G23_RS24530 fd8741370be289d7ef65410cf3e30208 284 Gene3D G3DSA:3.40.50.150 25 240 6.9E-27 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS13660 1c2f9d62242f5e9f817947587f138c49 105 SUPERFAMILY SSF51182 18 103 6.57E-22 T 10-11-2016 IPR011051 RmlC-like cupin domain A4G23_RS13660 1c2f9d62242f5e9f817947587f138c49 105 Gene3D G3DSA:2.60.120.10 2 104 5.6E-23 T 10-11-2016 IPR014710 RmlC-like jelly roll fold A4G23_RS13660 1c2f9d62242f5e9f817947587f138c49 105 Pfam PF07883 Cupin domain 33 100 7.9E-16 T 10-11-2016 IPR013096 Cupin 2, conserved barrel A4G23_RS06550 6e1a7af34ffc2da540f54e8924ae8d76 206 Gene3D G3DSA:1.20.120.80 25 205 1.4E-54 T 10-11-2016 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS06550 6e1a7af34ffc2da540f54e8924ae8d76 206 SUPERFAMILY SSF81452 12 204 2.88E-55 T 10-11-2016 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS06550 6e1a7af34ffc2da540f54e8924ae8d76 206 Pfam PF00510 Cytochrome c oxidase subunit III 26 204 1.5E-25 T 10-11-2016 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS19655 ab6d62c1450b85bc3fe40182c2591951 371 SUPERFAMILY SSF52540 2 217 8.81E-55 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS19655 ab6d62c1450b85bc3fe40182c2591951 371 Gene3D G3DSA:3.40.50.300 1 224 1.3E-57 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS19655 ab6d62c1450b85bc3fe40182c2591951 371 Pfam PF00005 ABC transporter 18 156 8.4E-24 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS19655 ab6d62c1450b85bc3fe40182c2591951 371 SMART SM00382 26 204 1.1E-9 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS13260 611771bcec97ec39e8454a668b160648 564 Gene3D G3DSA:3.40.605.10 93 328 4.7E-27 T 10-11-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A4G23_RS13260 611771bcec97ec39e8454a668b160648 564 SUPERFAMILY SSF53720 73 540 1.23E-55 T 10-11-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A4G23_RS13260 611771bcec97ec39e8454a668b160648 564 TIGRFAM TIGR02288 PaaN_2: phenylacetic acid degradation protein paaN 9 564 1.2E-292 T 10-11-2016 IPR011975 Phenylacetic acid degradation protein PaaN2 A4G23_RS13260 611771bcec97ec39e8454a668b160648 564 Pfam PF00171 Aldehyde dehydrogenase family 94 478 2.6E-31 T 10-11-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A4G23_RS13260 611771bcec97ec39e8454a668b160648 564 Gene3D G3DSA:3.40.309.10 329 525 1.2E-29 T 10-11-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 A4G23_RS03080 5bc296952b603c8329bd65db9e88705d 110 Pfam PF06947 Protein of unknown function (DUF1290) 21 108 2.4E-33 T 10-11-2016 IPR009709 Protein of unknown function DUF1290 A4G23_RS03080 5bc296952b603c8329bd65db9e88705d 110 PIRSF PIRSF018579 1 110 5.8E-46 T 10-11-2016 IPR009709 Protein of unknown function DUF1290 A4G23_RS10440 8ea8721f06d6f8a644ee488e8704af9d 203 SUPERFAMILY SSF48498 76 193 1.2E-18 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS10440 8ea8721f06d6f8a644ee488e8704af9d 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 51 1.3E-9 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS10440 8ea8721f06d6f8a644ee488e8704af9d 203 SUPERFAMILY SSF46689 3 77 3.99E-14 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS10440 8ea8721f06d6f8a644ee488e8704af9d 203 Pfam PF16925 Bacterial transcriptional repressor C-terminal 76 174 4.0E-8 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS10440 8ea8721f06d6f8a644ee488e8704af9d 203 Gene3D G3DSA:1.10.357.10 3 194 1.7E-36 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS18445 9e25fd82f26feecacca1c8c0190b754f 320 SUPERFAMILY SSF161098 115 305 1.44E-21 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS18445 9e25fd82f26feecacca1c8c0190b754f 320 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 136 320 4.8E-25 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS18445 9e25fd82f26feecacca1c8c0190b754f 320 Gene3D G3DSA:1.10.3720.10 112 317 5.9E-24 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS18445 9e25fd82f26feecacca1c8c0190b754f 320 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 43 83 2.4E-10 T 10-11-2016 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A4G23_RS19195 ef0688be04e14937686e02b71dc8f9e4 382 Gene3D G3DSA:1.10.10.10 4 100 2.5E-29 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS19195 ef0688be04e14937686e02b71dc8f9e4 382 SUPERFAMILY SSF46785 4 97 2.35E-24 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS19195 ef0688be04e14937686e02b71dc8f9e4 382 Gene3D G3DSA:1.20.1050.10 171 222 3.6E-4 T 10-11-2016 IPR010987 Glutathione S-transferase, C-terminal-like A4G23_RS19195 ef0688be04e14937686e02b71dc8f9e4 382 Pfam PF03551 Transcriptional regulator PadR-like family 14 82 4.5E-21 T 10-11-2016 IPR005149 Transcription regulator PadR, N-terminal A4G23_RS23435 b20c9e662a78262e1558dbe693e988fd 455 Pfam PF02624 YcaO cyclodehydratase, ATP-ad Mg2+-binding 64 411 2.8E-44 T 10-11-2016 IPR003776 YcaO-like domain A4G23_RS21320 a3e01917595fc7a23b15c15ecb915b1f 303 SUPERFAMILY SSF101478 10 293 2.62E-53 T 10-11-2016 IPR005502 ADP-ribosylation/Crystallin J1 A4G23_RS21320 a3e01917595fc7a23b15c15ecb915b1f 303 Pfam PF03747 ADP-ribosylglycohydrolase 17 276 1.2E-47 T 10-11-2016 IPR005502 ADP-ribosylation/Crystallin J1 A4G23_RS06870 a607c8b27fe9a2425cfcfe1a173db663 497 Gene3D G3DSA:3.20.20.80 23 124 4.1E-106 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS06870 a607c8b27fe9a2425cfcfe1a173db663 497 Gene3D G3DSA:3.20.20.80 194 479 4.1E-106 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS06870 a607c8b27fe9a2425cfcfe1a173db663 497 Pfam PF00128 Alpha amylase, catalytic domain 48 391 1.4E-72 T 10-11-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A4G23_RS06870 a607c8b27fe9a2425cfcfe1a173db663 497 Gene3D G3DSA:3.90.400.10 125 193 5.0E-28 T 10-11-2016 A4G23_RS06870 a607c8b27fe9a2425cfcfe1a173db663 497 SMART SM00642 33 415 4.0E-121 T 10-11-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A4G23_RS06870 a607c8b27fe9a2425cfcfe1a173db663 497 SUPERFAMILY SSF51445 23 478 3.87E-128 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS24620 c8378b04a5942d761989b7d4bfe709a6 149 SUPERFAMILY SSF55729 1 134 2.23E-21 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS24620 c8378b04a5942d761989b7d4bfe709a6 149 Pfam PF13673 Acetyltransferase (GNAT) domain 48 128 6.7E-14 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS24620 c8378b04a5942d761989b7d4bfe709a6 149 Gene3D G3DSA:3.40.630.30 3 133 2.0E-20 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS07335 2cc7867eed5566e16f7c5b9b34658acb 232 Gene3D G3DSA:3.40.50.150 37 158 8.2E-26 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS07335 2cc7867eed5566e16f7c5b9b34658acb 232 Pfam PF13489 Methyltransferase domain 40 141 6.2E-13 T 10-11-2016 A4G23_RS07335 2cc7867eed5566e16f7c5b9b34658acb 232 SUPERFAMILY SSF53335 37 215 5.47E-26 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS22200 61d10cc02f3d8117a0d2e2ea2c00828e 462 SUPERFAMILY SSF56281 12 238 9.66E-44 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS22200 61d10cc02f3d8117a0d2e2ea2c00828e 462 Gene3D G3DSA:3.40.250.10 351 456 4.0E-25 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS22200 61d10cc02f3d8117a0d2e2ea2c00828e 462 Gene3D G3DSA:3.60.15.10 10 237 1.0E-51 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS22200 61d10cc02f3d8117a0d2e2ea2c00828e 462 Gene3D G3DSA:3.40.250.10 258 339 3.9E-12 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS22200 61d10cc02f3d8117a0d2e2ea2c00828e 462 Pfam PF00753 Metallo-beta-lactamase superfamily 10 185 9.7E-8 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS22200 61d10cc02f3d8117a0d2e2ea2c00828e 462 SMART SM00450 259 358 8.0 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS22200 61d10cc02f3d8117a0d2e2ea2c00828e 462 SMART SM00450 363 459 5.8E-19 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS22200 61d10cc02f3d8117a0d2e2ea2c00828e 462 SMART SM00849 12 185 5.6E-21 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS22200 61d10cc02f3d8117a0d2e2ea2c00828e 462 SUPERFAMILY SSF52821 350 456 1.1E-27 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS22200 61d10cc02f3d8117a0d2e2ea2c00828e 462 SUPERFAMILY SSF52821 230 338 8.91E-14 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS22200 61d10cc02f3d8117a0d2e2ea2c00828e 462 Pfam PF00581 Rhodanese-like domain 365 455 2.5E-10 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS22200 61d10cc02f3d8117a0d2e2ea2c00828e 462 Pfam PF00581 Rhodanese-like domain 260 322 7.2E-5 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS07445 4310663ba7fc5ff8d889d48a8b7d0fb9 289 Pfam PF14472 Domain of unknown function (DUF4429) 142 231 1.4E-37 T 10-11-2016 IPR027860 Domain of unknown function DUF4429 A4G23_RS07445 4310663ba7fc5ff8d889d48a8b7d0fb9 289 Pfam PF14472 Domain of unknown function (DUF4429) 15 109 1.3E-13 T 10-11-2016 IPR027860 Domain of unknown function DUF4429 A4G23_RS07445 4310663ba7fc5ff8d889d48a8b7d0fb9 289 Pfam PF09851 Short C-terminal domain 259 286 8.7E-7 T 10-11-2016 IPR018649 SHOCT domain A4G23_RS04885 8e7a3d6515cdac78af9687e9f7a718b5 204 Gene3D G3DSA:1.10.10.10 85 158 4.4E-31 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS04885 8e7a3d6515cdac78af9687e9f7a718b5 204 PIRSF PIRSF019345 2 203 1.2E-52 T 10-11-2016 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 A4G23_RS04885 8e7a3d6515cdac78af9687e9f7a718b5 204 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 6 170 8.1E-32 T 10-11-2016 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 A4G23_RS04885 8e7a3d6515cdac78af9687e9f7a718b5 204 SUPERFAMILY SSF46785 4 80 4.76E-18 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS04885 8e7a3d6515cdac78af9687e9f7a718b5 204 Gene3D G3DSA:1.10.10.10 6 81 4.1E-28 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS04885 8e7a3d6515cdac78af9687e9f7a718b5 204 SUPERFAMILY SSF46785 85 158 7.11E-21 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS04885 8e7a3d6515cdac78af9687e9f7a718b5 204 Pfam PF04079 Segregation and condensation complex subunit ScpB 10 167 2.1E-56 T 10-11-2016 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 A4G23_RS27220 20520a6ddcfa376e7780e6c146d18dbb 242 Gene3D G3DSA:3.40.50.1820 9 126 4.3E-22 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS27220 20520a6ddcfa376e7780e6c146d18dbb 242 Gene3D G3DSA:3.40.50.1820 177 232 4.3E-22 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS27220 20520a6ddcfa376e7780e6c146d18dbb 242 SUPERFAMILY SSF53474 4 241 2.64E-32 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS27220 20520a6ddcfa376e7780e6c146d18dbb 242 Pfam PF00975 Thioesterase domain 19 230 9.4E-22 T 10-11-2016 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 A4G23_RS07695 ca66fc7aec13da92d21198806746f7e4 453 SUPERFAMILY SSF109604 223 443 5.56E-54 T 10-11-2016 A4G23_RS07695 ca66fc7aec13da92d21198806746f7e4 453 SUPERFAMILY SSF109604 26 192 5.56E-54 T 10-11-2016 A4G23_RS07695 ca66fc7aec13da92d21198806746f7e4 453 Hamap MF_01212 Deoxyguanosinetriphosphate triphosphohydrolase-like protein. 8 444 30.383 T 10-11-2016 IPR023023 Deoxyguanosinetriphosphate triphosphohydrolase, type 2 A4G23_RS07695 ca66fc7aec13da92d21198806746f7e4 453 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 83 444 5.0E-58 T 10-11-2016 IPR006261 Deoxyguanosinetriphosphate triphosphohydrolase GO:0000287|GO:0008832|GO:0046039 A4G23_RS07695 ca66fc7aec13da92d21198806746f7e4 453 Gene3D G3DSA:1.10.3410.10 239 371 4.0E-19 T 10-11-2016 IPR023293 Deoxyguanosinetriphosphate triphosphohydrolase, central domain A4G23_RS07695 ca66fc7aec13da92d21198806746f7e4 453 Pfam PF13286 Phosphohydrolase-associated domain 351 442 2.9E-19 T 10-11-2016 IPR026875 Phosphohydrolase-associated domain A4G23_RS07695 ca66fc7aec13da92d21198806746f7e4 453 SMART SM00471 83 252 4.1E-11 T 10-11-2016 IPR003607 HD/PDEase domain A4G23_RS07695 ca66fc7aec13da92d21198806746f7e4 453 Gene3D G3DSA:1.10.3210.10 17 238 4.0E-62 T 10-11-2016 IPR006674 HD domain A4G23_RS07695 ca66fc7aec13da92d21198806746f7e4 453 Pfam PF01966 HD domain 87 241 3.9E-15 T 10-11-2016 IPR006674 HD domain A4G23_RS16300 e5cac0bd36bb4f889091f9396de89622 142 Pfam PF01575 MaoC like domain 20 112 1.8E-26 T 10-11-2016 IPR002539 MaoC-like domain A4G23_RS16300 e5cac0bd36bb4f889091f9396de89622 142 PRINTS PR01483 Fatty acid synthase signature 47 68 2.9E-8 T 10-11-2016 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 A4G23_RS16300 e5cac0bd36bb4f889091f9396de89622 142 PRINTS PR01483 Fatty acid synthase signature 25 47 2.9E-8 T 10-11-2016 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 A4G23_RS16300 e5cac0bd36bb4f889091f9396de89622 142 Gene3D G3DSA:3.10.129.10 7 141 7.2E-40 T 10-11-2016 IPR029069 HotDog domain A4G23_RS16300 e5cac0bd36bb4f889091f9396de89622 142 SUPERFAMILY SSF54637 4 138 3.44E-31 T 10-11-2016 IPR029069 HotDog domain A4G23_RS20170 2324e110ca45fb3ef87bd9bb5712e94a 363 Gene3D G3DSA:3.20.10.10 181 348 6.9E-65 T 10-11-2016 A4G23_RS20170 2324e110ca45fb3ef87bd9bb5712e94a 363 Gene3D G3DSA:3.30.470.10 20 180 1.4E-73 T 10-11-2016 A4G23_RS20170 2324e110ca45fb3ef87bd9bb5712e94a 363 ProSitePatterns PS00770 Aminotransferases class-IV signature. 239 268 - T 10-11-2016 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 A4G23_RS20170 2324e110ca45fb3ef87bd9bb5712e94a 363 PIRSF PIRSF006468 5 363 6.2E-133 T 10-11-2016 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|Reactome: R-HSA-70895 A4G23_RS20170 2324e110ca45fb3ef87bd9bb5712e94a 363 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 49 360 1.3E-131 T 10-11-2016 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|Reactome: R-HSA-70895 A4G23_RS20170 2324e110ca45fb3ef87bd9bb5712e94a 363 SUPERFAMILY SSF56752 11 359 3.14E-118 T 10-11-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 A4G23_RS20170 2324e110ca45fb3ef87bd9bb5712e94a 363 Pfam PF01063 Amino-transferase class IV 75 317 7.3E-32 T 10-11-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 A4G23_RS15160 6ece7b61413cc11c2b5af8f5f4892d8c 389 ProDom PD120223 SCO3432 GENE ML2604 GP79 GP77 CGL2230 MB0190 148 347 2.0E-67 T 10-11-2016 A4G23_RS15160 6ece7b61413cc11c2b5af8f5f4892d8c 389 Pfam PF10979 Protein of unknown function (DUF2786) 146 185 2.4E-16 T 10-11-2016 IPR024498 Domain of unknown function DUF2786 A4G23_RS13050 f83776b328645cf4bc39796a73620633 688 Gene3D G3DSA:2.120.10.30 467 522 6.7E-5 T 10-11-2016 IPR011042 Six-bladed beta-propeller, TolB-like A4G23_RS13050 f83776b328645cf4bc39796a73620633 688 Gene3D G3DSA:2.120.10.30 674 685 6.7E-5 T 10-11-2016 IPR011042 Six-bladed beta-propeller, TolB-like A4G23_RS13050 f83776b328645cf4bc39796a73620633 688 Gene3D G3DSA:2.120.10.30 576 598 6.7E-5 T 10-11-2016 IPR011042 Six-bladed beta-propeller, TolB-like A4G23_RS13050 f83776b328645cf4bc39796a73620633 688 Pfam PF05787 Bacterial protein of unknown function (DUF839) 106 649 9.4E-173 T 10-11-2016 IPR008557 Protein of unknown function DUF839 A4G23_RS13050 f83776b328645cf4bc39796a73620633 688 SUPERFAMILY SSF63829 547 599 1.16E-7 T 10-11-2016 A4G23_RS13050 f83776b328645cf4bc39796a73620633 688 SUPERFAMILY SSF63829 414 508 1.16E-7 T 10-11-2016 A4G23_RS05965 128b2497e7f6d8f1ee114a9f74435168 242 Pfam PF01988 VIT family 28 235 2.4E-62 T 10-11-2016 IPR008217 Ccc1 family A4G23_RS09460 40286b5202fe94570087ab543946d3fb 140 SUPERFAMILY SSF102712 1 133 4.32E-28 T 10-11-2016 A4G23_RS09460 40286b5202fe94570087ab543946d3fb 140 SMART SM00232 1 134 1.5E-25 T 10-11-2016 IPR000555 JAB1/MPN/MOV34 metalloenzyme domain GO:0005515 A4G23_RS09460 40286b5202fe94570087ab543946d3fb 140 Pfam PF14464 Prokaryotic homologs of the JAB domain 7 110 2.7E-27 T 10-11-2016 IPR028090 JAB domain, prokaryotic A4G23_RS09460 40286b5202fe94570087ab543946d3fb 140 Gene3D G3DSA:3.40.140.10 1 136 8.3E-36 T 10-11-2016 A4G23_RS21305 0f644a820bd3a675f9f73fb14a443dc1 201 SUPERFAMILY SSF54909 16 77 5.36E-5 T 10-11-2016 IPR011008 Dimeric alpha-beta barrel A4G23_RS21305 0f644a820bd3a675f9f73fb14a443dc1 201 Pfam PF16291 Domain of unknown function (DUF4937 2 86 3.7E-28 T 10-11-2016 IPR032555 Domain of unknown function DUF4937 A4G23_RS20840 4aa558c8672b80c1714e96506b988dee 433 SUPERFAMILY SSF50156 128 235 2.23E-14 T 10-11-2016 IPR001478 PDZ domain GO:0005515 A4G23_RS20840 4aa558c8672b80c1714e96506b988dee 433 Gene3D G3DSA:2.30.42.10 122 236 1.5E-20 T 10-11-2016 IPR001478 PDZ domain GO:0005515 A4G23_RS20840 4aa558c8672b80c1714e96506b988dee 433 SMART SM00228 149 230 3.2E-4 T 10-11-2016 IPR001478 PDZ domain GO:0005515 A4G23_RS20840 4aa558c8672b80c1714e96506b988dee 433 Pfam PF02163 Peptidase family M50 13 385 2.6E-45 T 10-11-2016 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033 A4G23_RS06340 bfe1af04575b14a5723d0ec85e350a8c 304 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 26 298 4.4E-95 T 10-11-2016 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841 A4G23_RS06340 bfe1af04575b14a5723d0ec85e350a8c 304 Gene3D G3DSA:3.20.20.220 14 302 6.8E-103 T 10-11-2016 IPR029041 FAD-linked oxidoreductase-like A4G23_RS06340 bfe1af04575b14a5723d0ec85e350a8c 304 Pfam PF02219 Methylenetetrahydrofolate reductase 22 299 1.3E-106 T 10-11-2016 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 A4G23_RS06340 bfe1af04575b14a5723d0ec85e350a8c 304 SUPERFAMILY SSF51730 18 301 4.51E-92 T 10-11-2016 IPR029041 FAD-linked oxidoreductase-like A4G23_RS03505 5269cb3255432d56e23cc9e024652e75 714 Hamap MF_00983 Probable primosomal protein N' [priA]. 56 713 20.977 T 10-11-2016 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 A4G23_RS03505 5269cb3255432d56e23cc9e024652e75 714 SUPERFAMILY SSF52540 226 304 2.13E-5 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS03505 5269cb3255432d56e23cc9e024652e75 714 Gene3D G3DSA:3.40.50.300 226 316 8.4E-6 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS20910 b8fce9d2fd93355660af9690d77d9305 309 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 41 197 2.6E-46 T 10-11-2016 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 A4G23_RS20910 b8fce9d2fd93355660af9690d77d9305 309 SUPERFAMILY SSF88697 253 308 5.47E-11 T 10-11-2016 IPR015947 PUA-like domain A4G23_RS20910 b8fce9d2fd93355660af9690d77d9305 309 Pfam PF09142 tRNA Pseudouridine synthase II, C terminal 253 308 4.3E-19 T 10-11-2016 IPR015225 tRNA pseudouridine synthase II, TruB, subfamily 2, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4G23_RS20910 b8fce9d2fd93355660af9690d77d9305 309 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 198 240 2.7E-12 T 10-11-2016 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 A4G23_RS20910 b8fce9d2fd93355660af9690d77d9305 309 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 19 236 5.6E-64 T 10-11-2016 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4G23_RS20910 b8fce9d2fd93355660af9690d77d9305 309 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 18 308 16.67 T 10-11-2016 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4G23_RS20910 b8fce9d2fd93355660af9690d77d9305 309 SUPERFAMILY SSF55120 19 242 1.58E-68 T 10-11-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4G23_RS19990 1fb1b88b92f04e45293744cc668f067f 317 SUPERFAMILY SSF161098 102 297 1.3E-28 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS19990 1fb1b88b92f04e45293744cc668f067f 317 Gene3D G3DSA:1.10.3720.10 100 313 8.0E-27 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS19990 1fb1b88b92f04e45293744cc668f067f 317 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 133 316 4.8E-26 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS19990 1fb1b88b92f04e45293744cc668f067f 317 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 25 70 5.0E-15 T 10-11-2016 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A4G23_RS07125 d833c58394a36a8254fe0ec9101d1a8d 279 SUPERFAMILY SSF102705 3 261 7.72E-80 T 10-11-2016 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 A4G23_RS07125 d833c58394a36a8254fe0ec9101d1a8d 279 Gene3D G3DSA:3.40.1390.30 115 212 8.6E-33 T 10-11-2016 A4G23_RS07125 d833c58394a36a8254fe0ec9101d1a8d 279 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 7 240 2.5E-67 T 10-11-2016 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 A4G23_RS07125 d833c58394a36a8254fe0ec9101d1a8d 279 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 4 243 8.0E-47 T 10-11-2016 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 A4G23_RS07125 d833c58394a36a8254fe0ec9101d1a8d 279 Gene3D G3DSA:3.40.1390.30 3 114 2.5E-41 T 10-11-2016 A4G23_RS05560 e9b32e368cc0db39429cf2024daf965c 418 Gene3D G3DSA:3.40.640.10 42 293 1.0E-86 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS05560 e9b32e368cc0db39429cf2024daf965c 418 SUPERFAMILY SSF53383 9 413 1.97E-125 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS05560 e9b32e368cc0db39429cf2024daf965c 418 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 12 418 1.4E-183 T 10-11-2016 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 A4G23_RS05560 e9b32e368cc0db39429cf2024daf965c 418 Gene3D G3DSA:3.90.1150.10 294 412 8.4E-31 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS05560 e9b32e368cc0db39429cf2024daf965c 418 Pfam PF00266 Aminotransferase class-V 31 406 2.4E-150 T 10-11-2016 IPR000192 Aminotransferase class V domain A4G23_RS16325 fa15941e382e7fb27b940c91d4d638e8 408 Gene3D G3DSA:3.90.1150.10 282 405 4.4E-36 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS16325 fa15941e382e7fb27b940c91d4d638e8 408 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 238 262 4.3E-11 T 10-11-2016 A4G23_RS16325 fa15941e382e7fb27b940c91d4d638e8 408 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 171 195 4.3E-11 T 10-11-2016 A4G23_RS16325 fa15941e382e7fb27b940c91d4d638e8 408 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 124 145 4.3E-11 T 10-11-2016 A4G23_RS16325 fa15941e382e7fb27b940c91d4d638e8 408 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 207 230 4.3E-11 T 10-11-2016 A4G23_RS16325 fa15941e382e7fb27b940c91d4d638e8 408 Pfam PF00155 Aminotransferase class I and II 40 396 1.1E-74 T 10-11-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4G23_RS16325 fa15941e382e7fb27b940c91d4d638e8 408 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 244 257 - T 10-11-2016 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 A4G23_RS16325 fa15941e382e7fb27b940c91d4d638e8 408 SUPERFAMILY SSF53383 12 405 1.77E-114 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS16325 fa15941e382e7fb27b940c91d4d638e8 408 Gene3D G3DSA:3.40.640.10 52 281 1.7E-77 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS10550 3c4219800e0f4d32f496f0b0f0b71875 325 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 12 322 46.672 T 10-11-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 A4G23_RS10550 3c4219800e0f4d32f496f0b0f0b71875 325 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 136 151 - T 10-11-2016 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 A4G23_RS10550 3c4219800e0f4d32f496f0b0f0b71875 325 SMART SM01400 12 128 3.8E-71 T 10-11-2016 A4G23_RS10550 3c4219800e0f4d32f496f0b0f0b71875 325 Gene3D G3DSA:3.40.50.2020 9 167 3.2E-69 T 10-11-2016 IPR029057 Phosphoribosyltransferase-like A4G23_RS10550 3c4219800e0f4d32f496f0b0f0b71875 325 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 13 322 1.1E-114 T 10-11-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 A4G23_RS10550 3c4219800e0f4d32f496f0b0f0b71875 325 SUPERFAMILY SSF53271 77 313 7.85E-62 T 10-11-2016 IPR029057 Phosphoribosyltransferase-like A4G23_RS10550 3c4219800e0f4d32f496f0b0f0b71875 325 Gene3D G3DSA:3.40.50.2020 168 293 2.0E-46 T 10-11-2016 IPR029057 Phosphoribosyltransferase-like A4G23_RS10550 3c4219800e0f4d32f496f0b0f0b71875 325 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 12 128 1.4E-44 T 10-11-2016 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 A4G23_RS10550 3c4219800e0f4d32f496f0b0f0b71875 325 Pfam PF14572 Phosphoribosyl synthetase-associated domain 215 321 1.3E-23 T 10-11-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 A4G23_RS23375 1c663a8b0f1b635be7da463adac39bda 84 Pfam PF01361 Tautomerase enzyme 2 53 2.7E-7 T 10-11-2016 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 A4G23_RS23375 1c663a8b0f1b635be7da463adac39bda 84 Gene3D G3DSA:3.30.429.20 2 52 5.0E-9 T 10-11-2016 A4G23_RS23375 1c663a8b0f1b635be7da463adac39bda 84 SUPERFAMILY SSF55331 2 74 1.02E-14 T 10-11-2016 IPR014347 Tautomerase/MIF superfamily A4G23_RS25580 91e794b59523f2f290655e8440db91a1 328 Gene3D G3DSA:3.40.50.1980 37 157 6.5E-28 T 10-11-2016 A4G23_RS25580 91e794b59523f2f290655e8440db91a1 328 SUPERFAMILY SSF53807 39 321 1.49E-50 T 10-11-2016 A4G23_RS25580 91e794b59523f2f290655e8440db91a1 328 Pfam PF01497 Periplasmic binding protein 58 302 8.2E-22 T 10-11-2016 IPR002491 ABC transporter periplasmic binding domain GO:0005488 A4G23_RS25580 91e794b59523f2f290655e8440db91a1 328 Gene3D G3DSA:3.40.50.1980 158 327 4.6E-40 T 10-11-2016 A4G23_RS26275 81be72a083050c60b180fb71737efc0b 208 Gene3D G3DSA:3.40.50.2300 36 119 9.1E-6 T 10-11-2016 A4G23_RS26275 81be72a083050c60b180fb71737efc0b 208 Gene3D G3DSA:1.10.10.10 148 208 3.9E-20 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS26275 81be72a083050c60b180fb71737efc0b 208 SUPERFAMILY SSF46894 143 208 1.84E-16 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS26275 81be72a083050c60b180fb71737efc0b 208 SMART SM00421 145 202 6.9E-17 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS26275 81be72a083050c60b180fb71737efc0b 208 Pfam PF00196 Bacterial regulatory proteins, luxR family 147 202 1.9E-15 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS26275 81be72a083050c60b180fb71737efc0b 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 148 162 1.3E-5 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS26275 81be72a083050c60b180fb71737efc0b 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 178 1.3E-5 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS00495 cb3cc338cc6c78b0cfde2fa5b9db52c9 238 Pfam PF06386 Gas vesicle synthesis protein GvpL/GvpF 3 237 6.3E-66 T 10-11-2016 IPR009430 Gas vesicle protein GvpL/GvpF GO:0031411|GO:0031412 A4G23_RS18520 4b4ac8fd41019e65f31e79ff8276fe96 367 SUPERFAMILY SSF55031 178 278 3.14E-21 T 10-11-2016 IPR011650 Peptidase M20, dimerisation domain A4G23_RS18520 4b4ac8fd41019e65f31e79ff8276fe96 367 TIGRFAM TIGR01900 dapE-gram_pos: succinyl-diaminopimelate desuccinylase 22 366 4.7E-157 T 10-11-2016 IPR010174 Succinyl-diaminopimelate desuccinylase, DapE GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 A4G23_RS18520 4b4ac8fd41019e65f31e79ff8276fe96 367 Gene3D G3DSA:3.40.630.10 23 178 3.4E-42 T 10-11-2016 A4G23_RS18520 4b4ac8fd41019e65f31e79ff8276fe96 367 Gene3D G3DSA:3.40.630.10 288 365 3.4E-42 T 10-11-2016 A4G23_RS18520 4b4ac8fd41019e65f31e79ff8276fe96 367 Pfam PF07687 Peptidase dimerisation domain 178 276 2.9E-16 T 10-11-2016 IPR011650 Peptidase M20, dimerisation domain A4G23_RS18520 4b4ac8fd41019e65f31e79ff8276fe96 367 Gene3D G3DSA:3.30.70.360 179 278 1.1E-24 T 10-11-2016 IPR011650 Peptidase M20, dimerisation domain A4G23_RS18520 4b4ac8fd41019e65f31e79ff8276fe96 367 Pfam PF01546 Peptidase family M20/M25/M40 77 360 8.2E-21 T 10-11-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A4G23_RS18520 4b4ac8fd41019e65f31e79ff8276fe96 367 SUPERFAMILY SSF53187 288 365 5.74E-40 T 10-11-2016 A4G23_RS18520 4b4ac8fd41019e65f31e79ff8276fe96 367 SUPERFAMILY SSF53187 24 190 5.74E-40 T 10-11-2016 A4G23_RS05580 207a321c3f95c6a354f5aa30dc33b2a6 471 Pfam PF01458 Uncharacterized protein family (UPF0051) 217 442 9.6E-76 T 10-11-2016 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 A4G23_RS05580 207a321c3f95c6a354f5aa30dc33b2a6 471 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 15 462 3.7E-221 T 10-11-2016 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 A4G23_RS05580 207a321c3f95c6a354f5aa30dc33b2a6 471 SUPERFAMILY SSF101960 37 468 3.14E-141 T 10-11-2016 A4G23_RS14265 bc53e9b48567aa6e4f067ed94cd32286 316 Pfam PF00672 HAMP domain 37 104 1.5E-10 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS14265 bc53e9b48567aa6e4f067ed94cd32286 316 Pfam PF07730 Histidine kinase 120 184 2.0E-16 T 10-11-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4G23_RS14265 bc53e9b48567aa6e4f067ed94cd32286 316 Gene3D G3DSA:3.30.565.10 149 174 3.1E-6 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS14265 bc53e9b48567aa6e4f067ed94cd32286 316 Gene3D G3DSA:3.30.565.10 219 311 3.1E-6 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS14265 bc53e9b48567aa6e4f067ed94cd32286 316 SUPERFAMILY SSF55874 193 308 1.81E-13 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS14265 bc53e9b48567aa6e4f067ed94cd32286 316 SMART SM00304 55 107 1.1E-10 T 10-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A4G23_RS16945 f1fffa1947ea5f4a64eebf970d20525e 235 SUPERFAMILY SSF50800 1 199 7.32E-52 T 10-11-2016 IPR011037 Pyruvate kinase-like, insert domain A4G23_RS16945 f1fffa1947ea5f4a64eebf970d20525e 235 Gene3D G3DSA:2.40.33.20 1 213 1.6E-66 T 10-11-2016 IPR015808 Molybdenum cofactor sulfurase, C-terminal-like A4G23_RS16945 f1fffa1947ea5f4a64eebf970d20525e 235 Pfam PF03473 MOSC domain 57 170 1.6E-20 T 10-11-2016 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 A4G23_RS26725 3ab826ed7774b50e5351f1b361aa0b4a 140 SUPERFAMILY SSF54427 11 138 8.32E-28 T 10-11-2016 IPR032710 NTF2-like domain A4G23_RS26725 3ab826ed7774b50e5351f1b361aa0b4a 140 Gene3D G3DSA:3.10.450.50 9 138 1.5E-29 T 10-11-2016 IPR032710 NTF2-like domain A4G23_RS26725 3ab826ed7774b50e5351f1b361aa0b4a 140 Pfam PF12680 SnoaL-like domain 15 125 6.5E-14 T 10-11-2016 IPR009959 Polyketide cyclase SnoaL-like domain A4G23_RS18230 bd586e28bc2dd5cad5ddefc495e4acc3 573 SUPERFAMILY SSF55874 486 570 1.32E-6 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS18230 bd586e28bc2dd5cad5ddefc495e4acc3 573 Pfam PF13581 Histidine kinase-like ATPase domain 467 553 3.4E-9 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS18230 bd586e28bc2dd5cad5ddefc495e4acc3 573 SMART SM00331 228 445 8.1E-38 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS18230 bd586e28bc2dd5cad5ddefc495e4acc3 573 SUPERFAMILY SSF81606 242 446 1.39E-8 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS18230 bd586e28bc2dd5cad5ddefc495e4acc3 573 SUPERFAMILY SSF55781 153 214 3.29E-6 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS18230 bd586e28bc2dd5cad5ddefc495e4acc3 573 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 254 446 1.7E-53 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS18230 bd586e28bc2dd5cad5ddefc495e4acc3 573 Gene3D G3DSA:3.30.450.40 17 204 8.2E-24 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS08410 fb0d7515eb4646afaf8c511bc120f9db 154 Gene3D G3DSA:3.10.180.10 11 134 1.4E-29 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS08410 fb0d7515eb4646afaf8c511bc120f9db 154 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 10 132 7.9E-16 T 10-11-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4G23_RS08410 fb0d7515eb4646afaf8c511bc120f9db 154 SUPERFAMILY SSF54593 6 142 4.56E-30 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS08410 fb0d7515eb4646afaf8c511bc120f9db 154 ProSitePatterns PS00934 Glyoxalase I signature 1. 11 32 - T 10-11-2016 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 A4G23_RS27075 bbd7cdebbb2599c91e161bdc2ecd8859 206 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 7 200 1.6E-53 T 10-11-2016 IPR006070 YrdC-like domain GO:0003725 A4G23_RS27075 bbd7cdebbb2599c91e161bdc2ecd8859 206 SUPERFAMILY SSF55821 1 204 2.2E-60 T 10-11-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain A4G23_RS27075 bbd7cdebbb2599c91e161bdc2ecd8859 206 Pfam PF01300 Telomere recombination 22 198 7.2E-44 T 10-11-2016 IPR006070 YrdC-like domain GO:0003725 A4G23_RS27075 bbd7cdebbb2599c91e161bdc2ecd8859 206 Gene3D G3DSA:3.90.870.10 2 204 2.2E-61 T 10-11-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain A4G23_RS22785 e649d40b4757fb972dd8e4080b5abd10 162 SUPERFAMILY SSF55729 1 156 9.81E-31 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS22785 e649d40b4757fb972dd8e4080b5abd10 162 Pfam PF00583 Acetyltransferase (GNAT) family 54 133 2.4E-12 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS22785 e649d40b4757fb972dd8e4080b5abd10 162 Gene3D G3DSA:3.40.630.30 1 158 2.2E-36 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS22290 1445baa4291955a8da2eac097014fe54 56 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 52 13.273 T 10-11-2016 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS22290 1445baa4291955a8da2eac097014fe54 56 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 37 1.1E-11 T 10-11-2016 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS22290 1445baa4291955a8da2eac097014fe54 56 Pfam PF01783 Ribosomal L32p protein family 2 46 6.9E-14 T 10-11-2016 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS22290 1445baa4291955a8da2eac097014fe54 56 SUPERFAMILY SSF57829 1 38 1.34E-9 T 10-11-2016 IPR011332 Zinc-binding ribosomal protein GO:0006412 A4G23_RS08530 61dac4c9b507a299a75776451a062962 134 SUPERFAMILY SSF46458 12 132 2.67E-37 T 10-11-2016 IPR009050 Globin-like A4G23_RS08530 61dac4c9b507a299a75776451a062962 134 Pfam PF01152 Bacterial-like globin 13 130 4.2E-36 T 10-11-2016 IPR001486 Truncated hemoglobin GO:0019825 A4G23_RS08530 61dac4c9b507a299a75776451a062962 134 Gene3D G3DSA:1.10.490.10 11 132 4.8E-46 T 10-11-2016 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 A4G23_RS11615 5232d2b3b6d15b362e1765e01943e73d 251 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 11 210 1.7E-16 T 10-11-2016 IPR013830 SGNH hydrolase-type esterase domain A4G23_RS11615 5232d2b3b6d15b362e1765e01943e73d 251 SUPERFAMILY SSF52266 7 31 4.43E-22 T 10-11-2016 IPR013830 SGNH hydrolase-type esterase domain A4G23_RS11615 5232d2b3b6d15b362e1765e01943e73d 251 SUPERFAMILY SSF52266 77 224 4.43E-22 T 10-11-2016 IPR013830 SGNH hydrolase-type esterase domain A4G23_RS11615 5232d2b3b6d15b362e1765e01943e73d 251 Gene3D G3DSA:3.40.50.1110 5 224 1.2E-21 T 10-11-2016 IPR013830 SGNH hydrolase-type esterase domain A4G23_RS18420 ea27d17dd57c3eb262e26baf3dbbb2dd 325 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 124 323 4.8E-33 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS18420 ea27d17dd57c3eb262e26baf3dbbb2dd 325 SUPERFAMILY SSF161098 99 310 1.9E-10 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS18420 ea27d17dd57c3eb262e26baf3dbbb2dd 325 Gene3D G3DSA:1.10.3720.10 97 318 3.7E-10 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS08310 eaf145a746924dea3ded4e54570e1714 201 Pfam PF00574 Clp protease 17 188 2.5E-75 T 10-11-2016 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA A4G23_RS08310 eaf145a746924dea3ded4e54570e1714 201 Gene3D G3DSA:3.90.226.10 18 189 4.0E-74 T 10-11-2016 IPR029045 ClpP/crotonase-like domain A4G23_RS08310 eaf145a746924dea3ded4e54570e1714 201 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 1 190 38.327 T 10-11-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4G23_RS08310 eaf145a746924dea3ded4e54570e1714 201 SUPERFAMILY SSF52096 17 189 6.7E-66 T 10-11-2016 IPR029045 ClpP/crotonase-like domain A4G23_RS08310 eaf145a746924dea3ded4e54570e1714 201 PRINTS PR00127 Clp protease catalytic subunit P signature 165 184 5.1E-45 T 10-11-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4G23_RS08310 eaf145a746924dea3ded4e54570e1714 201 PRINTS PR00127 Clp protease catalytic subunit P signature 108 127 5.1E-45 T 10-11-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4G23_RS08310 eaf145a746924dea3ded4e54570e1714 201 PRINTS PR00127 Clp protease catalytic subunit P signature 87 104 5.1E-45 T 10-11-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4G23_RS08310 eaf145a746924dea3ded4e54570e1714 201 PRINTS PR00127 Clp protease catalytic subunit P signature 56 76 5.1E-45 T 10-11-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4G23_RS08310 eaf145a746924dea3ded4e54570e1714 201 PRINTS PR00127 Clp protease catalytic subunit P signature 17 32 5.1E-45 T 10-11-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4G23_RS09975 78d5e4bf041db8437773b2c649ebde09 1273 Gene3D G3DSA:3.90.550.10 24 103 1.2E-31 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS09975 78d5e4bf041db8437773b2c649ebde09 1273 Gene3D G3DSA:3.90.550.10 140 277 1.2E-31 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS09975 78d5e4bf041db8437773b2c649ebde09 1273 SUPERFAMILY SSF53448 139 280 3.86E-34 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS09975 78d5e4bf041db8437773b2c649ebde09 1273 SUPERFAMILY SSF53448 23 100 3.86E-34 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS09975 78d5e4bf041db8437773b2c649ebde09 1273 Pfam PF13641 Glycosyltransferase like family 2 32 277 6.5E-17 T 10-11-2016 A4G23_RS02755 7c331215c8682b6449256b2272b57f77 187 Gene3D G3DSA:3.40.470.10 19 180 7.8E-57 T 10-11-2016 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4G23_RS02755 7c331215c8682b6449256b2272b57f77 187 SMART SM00986 20 181 1.9E-8 T 10-11-2016 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4G23_RS02755 7c331215c8682b6449256b2272b57f77 187 SUPERFAMILY SSF52141 18 178 1.05E-46 T 10-11-2016 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4G23_RS02755 7c331215c8682b6449256b2272b57f77 187 Pfam PF03167 Uracil DNA glycosylase superfamily 22 174 2.7E-26 T 10-11-2016 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4G23_RS02755 7c331215c8682b6449256b2272b57f77 187 SMART SM00987 20 181 1.9E-8 T 10-11-2016 A4G23_RS23455 2609780a3141fb9108c870c7fda4302e 617 Pfam PF07905 Purine catabolism regulatory protein-like family 6 120 1.1E-26 T 10-11-2016 IPR012914 Purine catabolism PurC-like domain A4G23_RS23455 2609780a3141fb9108c870c7fda4302e 617 Pfam PF13556 PucR C-terminal helix-turn-helix domain 558 615 1.1E-21 T 10-11-2016 IPR025736 PucR C-terminal helix-turn-helix domain A4G23_RS02850 31a801b20337bff408f10608c1a64167 262 SMART SM00382 31 220 4.6E-10 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS02850 31a801b20337bff408f10608c1a64167 262 SUPERFAMILY SSF52540 5 226 1.74E-55 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS02850 31a801b20337bff408f10608c1a64167 262 Pfam PF00005 ABC transporter 22 172 7.2E-30 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS02850 31a801b20337bff408f10608c1a64167 262 Gene3D G3DSA:3.40.50.300 5 221 7.9E-58 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS18325 0d73e37ef8f0d9120615b1ad493ae388 521 Pfam PF01939 Protein of unknown function DUF91 1 80 5.0E-7 T 10-11-2016 IPR002793 Endonuclease NucS A4G23_RS23885 e8f5474253622c77fac0b06461330b6a 209 Pfam PF00072 Response regulator receiver domain 6 119 6.0E-22 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS23885 e8f5474253622c77fac0b06461330b6a 209 Pfam PF00196 Bacterial regulatory proteins, luxR family 147 201 1.1E-19 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS23885 e8f5474253622c77fac0b06461330b6a 209 SMART SM00448 3 119 2.8E-27 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS23885 e8f5474253622c77fac0b06461330b6a 209 SUPERFAMILY SSF52172 2 137 1.57E-27 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS23885 e8f5474253622c77fac0b06461330b6a 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 190 6.2E-14 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS23885 e8f5474253622c77fac0b06461330b6a 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 148 162 6.2E-14 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS23885 e8f5474253622c77fac0b06461330b6a 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 178 6.2E-14 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS23885 e8f5474253622c77fac0b06461330b6a 209 Gene3D G3DSA:3.40.50.2300 2 124 9.7E-30 T 10-11-2016 A4G23_RS23885 e8f5474253622c77fac0b06461330b6a 209 SUPERFAMILY SSF46894 134 208 9.86E-21 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS23885 e8f5474253622c77fac0b06461330b6a 209 ProSitePatterns PS00622 LuxR-type HTH domain signature. 162 189 - T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS23885 e8f5474253622c77fac0b06461330b6a 209 SMART SM00421 145 202 3.1E-22 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS23885 e8f5474253622c77fac0b06461330b6a 209 Gene3D G3DSA:1.10.10.10 125 208 3.5E-26 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS05315 ce3ce46bba62147086a28739690d26af 99 Gene3D G3DSA:3.30.420.180 5 99 2.1E-27 T 10-11-2016 IPR002750 CobE/GbiG C-terminal domain GO:0009236 A4G23_RS05315 ce3ce46bba62147086a28739690d26af 99 Pfam PF01890 Cobalamin synthesis G C-terminus 6 99 3.7E-27 T 10-11-2016 IPR002750 CobE/GbiG C-terminal domain GO:0009236 A4G23_RS05315 ce3ce46bba62147086a28739690d26af 99 SUPERFAMILY SSF159664 5 99 6.41E-27 T 10-11-2016 IPR002750 CobE/GbiG C-terminal domain GO:0009236 A4G23_RS15265 28f112f5c4e800a2319fb61e3addfdcb 179 SUPERFAMILY SSF53271 4 177 9.83E-55 T 10-11-2016 IPR029057 Phosphoribosyltransferase-like A4G23_RS15265 28f112f5c4e800a2319fb61e3addfdcb 179 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 8 172 5.9E-65 T 10-11-2016 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 A4G23_RS15265 28f112f5c4e800a2319fb61e3addfdcb 179 Pfam PF00156 Phosphoribosyl transferase domain 14 159 2.0E-24 T 10-11-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 A4G23_RS15265 28f112f5c4e800a2319fb61e3addfdcb 179 Gene3D G3DSA:3.40.50.2020 3 177 8.5E-80 T 10-11-2016 IPR029057 Phosphoribosyltransferase-like A4G23_RS14585 dad83cdbab568da95901997ca9b928ef 333 SUPERFAMILY SSF111331 4 130 8.28E-7 T 10-11-2016 IPR016064 NAD kinase/diacylglycerol kinase-like domain A4G23_RS14585 dad83cdbab568da95901997ca9b928ef 333 SUPERFAMILY SSF111331 213 325 8.28E-7 T 10-11-2016 IPR016064 NAD kinase/diacylglycerol kinase-like domain A4G23_RS19090 737d642246811c274f93720338a4a0a9 224 PIRSF PIRSF016573 1 224 3.2E-106 T 10-11-2016 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 A4G23_RS19090 737d642246811c274f93720338a4a0a9 224 SUPERFAMILY SSF55486 85 213 1.04E-30 T 10-11-2016 A4G23_RS19090 737d642246811c274f93720338a4a0a9 224 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 123 147 3.8E-62 T 10-11-2016 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 A4G23_RS19090 737d642246811c274f93720338a4a0a9 224 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 91 117 3.8E-62 T 10-11-2016 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 A4G23_RS19090 737d642246811c274f93720338a4a0a9 224 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 200 214 3.8E-62 T 10-11-2016 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 A4G23_RS19090 737d642246811c274f93720338a4a0a9 224 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 173 197 3.8E-62 T 10-11-2016 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 A4G23_RS19090 737d642246811c274f93720338a4a0a9 224 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 148 172 3.8E-62 T 10-11-2016 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 A4G23_RS19090 737d642246811c274f93720338a4a0a9 224 Gene3D G3DSA:3.40.390.10 86 213 3.6E-37 T 10-11-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 A4G23_RS19090 737d642246811c274f93720338a4a0a9 224 Pfam PF02031 Streptomyces extracellular neutral proteinase (M7) family 84 215 2.1E-78 T 10-11-2016 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 A4G23_RS19090 737d642246811c274f93720338a4a0a9 224 ProDom PD016028 PROTEASE METALLOPROTEASE EXTRACELLULAR NEUTRAL SMALL METAL-BINDING ZINC HYDROLASE SNAPALYSIN ZYMOGEN 93 215 2.0E-54 T 10-11-2016 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 A4G23_RS25355 23bba45bab2931dea3fa9269d0a6237e 268 SUPERFAMILY SSF56112 9 268 5.23E-58 T 10-11-2016 IPR011009 Protein kinase-like domain A4G23_RS25355 23bba45bab2931dea3fa9269d0a6237e 268 Gene3D G3DSA:3.90.1200.10 92 268 2.1E-50 T 10-11-2016 A4G23_RS25355 23bba45bab2931dea3fa9269d0a6237e 268 Pfam PF01636 Phosphotransferase enzyme family 28 253 7.3E-35 T 10-11-2016 IPR002575 Aminoglycoside phosphotransferase A4G23_RS25355 23bba45bab2931dea3fa9269d0a6237e 268 PIRSF PIRSF000706 3 268 3.1E-98 T 10-11-2016 IPR024165 Aminoglycoside 3-phosphotransferase GO:0005524|GO:0016773|GO:0046677 A4G23_RS25355 23bba45bab2931dea3fa9269d0a6237e 268 Gene3D G3DSA:3.30.200.20 4 91 1.5E-25 T 10-11-2016 A4G23_RS09775 436e8ddbd1729d39a5df90848f0676b8 272 Gene3D G3DSA:1.10.3720.10 7 260 2.5E-55 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS09775 436e8ddbd1729d39a5df90848f0676b8 272 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 256 7.4E-13 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS09775 436e8ddbd1729d39a5df90848f0676b8 272 SUPERFAMILY SSF161098 7 272 7.85E-64 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS25795 e289de68d4deb59100a2d16b2f49fbb4 215 PRINTS PR01218 Pistil-specific extensin-like signature 107 130 2.1E-5 T 10-11-2016 IPR003882 Pistil-specific extensin-like protein GO:0005199 A4G23_RS25795 e289de68d4deb59100a2d16b2f49fbb4 215 PRINTS PR01218 Pistil-specific extensin-like signature 141 159 2.1E-5 T 10-11-2016 IPR003882 Pistil-specific extensin-like protein GO:0005199 A4G23_RS02545 d0fec4ccebe3e2bb8cf9532aea163848 91 Gene3D G3DSA:3.40.1620.10 3 51 1.4E-14 T 10-11-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM A4G23_RS02545 d0fec4ccebe3e2bb8cf9532aea163848 91 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 5 51 6.1E-14 T 10-11-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM A4G23_RS02545 d0fec4ccebe3e2bb8cf9532aea163848 91 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 4 50 1.4E-16 T 10-11-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM A4G23_RS02545 d0fec4ccebe3e2bb8cf9532aea163848 91 SUPERFAMILY SSF143120 5 51 1.06E-11 T 10-11-2016 A4G23_RS05445 aea3af413aec602a16203257a46cbc18 357 SUPERFAMILY SSF55347 114 274 8.5E-12 T 10-11-2016 A4G23_RS05445 aea3af413aec602a16203257a46cbc18 357 Gene3D G3DSA:3.30.360.10 123 306 1.0E-17 T 10-11-2016 A4G23_RS05445 aea3af413aec602a16203257a46cbc18 357 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 33 106 1.7E-10 T 10-11-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 A4G23_RS05445 aea3af413aec602a16203257a46cbc18 357 Gene3D G3DSA:3.40.50.720 6 122 4.4E-20 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS05445 aea3af413aec602a16203257a46cbc18 357 SUPERFAMILY SSF51735 5 134 8.3E-23 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS01850 986d09db162d489c900dfba238239ef5 276 Pfam PF07398 MDMPI C-terminal domain 145 265 2.2E-10 T 10-11-2016 IPR010872 MDMPI C-terminal A4G23_RS01850 986d09db162d489c900dfba238239ef5 276 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 10 196 1.5E-24 T 10-11-2016 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type A4G23_RS01850 986d09db162d489c900dfba238239ef5 276 SUPERFAMILY SSF109854 2 134 1.83E-10 T 10-11-2016 A4G23_RS01850 986d09db162d489c900dfba238239ef5 276 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 12 129 7.3E-21 T 10-11-2016 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 A4G23_RS17975 9a6ef638c58580b8cb6779b2cdc90caf 293 Gene3D G3DSA:3.40.50.10320 3 291 8.7E-86 T 10-11-2016 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 A4G23_RS17975 9a6ef638c58580b8cb6779b2cdc90caf 293 Pfam PF02585 GlcNAc-PI de-N-acetylase 8 154 5.9E-26 T 10-11-2016 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 A4G23_RS17975 9a6ef638c58580b8cb6779b2cdc90caf 293 SUPERFAMILY SSF102588 4 291 8.76E-74 T 10-11-2016 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 A4G23_RS17975 9a6ef638c58580b8cb6779b2cdc90caf 293 Hamap MF_01482 Mycothiol S-conjugate amidase [mca]. 8 290 51.645 T 10-11-2016 IPR017811 Mycothiol S-conjugate amidase Mca GO:0010126 KEGG: 00311+3.5.1.11 A4G23_RS17975 9a6ef638c58580b8cb6779b2cdc90caf 293 TIGRFAM TIGR03446 mycothiol_Mca: mycothiol conjugate amidase Mca 5 289 1.9E-147 T 10-11-2016 IPR017811 Mycothiol S-conjugate amidase Mca GO:0010126 KEGG: 00311+3.5.1.11 A4G23_RS26505 eaacdbda1dc106d59e95249fae8a64d4 682 Pfam PF04865 Baseplate J-like protein 437 607 4.9E-11 T 10-11-2016 IPR006949 Baseplate protein J-like A4G23_RS26505 eaacdbda1dc106d59e95249fae8a64d4 682 TIGRFAM TIGR02243 TIGR02243: putative baseplate assembly protein 42 647 6.2E-70 T 10-11-2016 IPR011749 Conserved hypothetical protein CHP02243 A4G23_RS01565 eb9ed5bb61c908f949a4cf3edbc97eed 135 Pfam PF01042 Endoribonuclease L-PSP 13 133 1.9E-17 T 10-11-2016 IPR006175 YjgF/YER057c/UK114 family A4G23_RS01565 eb9ed5bb61c908f949a4cf3edbc97eed 135 SUPERFAMILY SSF55298 13 135 3.3E-25 T 10-11-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like A4G23_RS01565 eb9ed5bb61c908f949a4cf3edbc97eed 135 Gene3D G3DSA:3.30.1330.40 2 135 2.7E-30 T 10-11-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like A4G23_RS06535 2ad0b097d4ba967a6a90785f7a77bd7a 541 Pfam PF13631 Cytochrome b(N-terminal)/b6/petB 120 293 1.6E-58 T 10-11-2016 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 A4G23_RS06535 2ad0b097d4ba967a6a90785f7a77bd7a 541 SUPERFAMILY SSF81342 19 298 1.88E-62 T 10-11-2016 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 A4G23_RS06535 2ad0b097d4ba967a6a90785f7a77bd7a 541 Gene3D G3DSA:1.20.810.10 19 440 9.6E-90 T 10-11-2016 IPR027387 Cytochrome b/b6-like domain Reactome: R-HSA-611105 A4G23_RS18545 55856a0a4b0aa60708b84933c4401190 260 SUPERFAMILY SSF52096 2 259 1.12E-77 T 10-11-2016 IPR029045 ClpP/crotonase-like domain A4G23_RS18545 55856a0a4b0aa60708b84933c4401190 260 Gene3D G3DSA:1.10.12.10 202 260 2.1E-16 T 10-11-2016 IPR014748 Crontonase, C-terminal A4G23_RS18545 55856a0a4b0aa60708b84933c4401190 260 Gene3D G3DSA:3.90.226.10 3 200 2.4E-61 T 10-11-2016 IPR029045 ClpP/crotonase-like domain A4G23_RS18545 55856a0a4b0aa60708b84933c4401190 260 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 258 7.6E-57 T 10-11-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 A4G23_RS18545 55856a0a4b0aa60708b84933c4401190 260 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 101 121 - T 10-11-2016 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 A4G23_RS12035 588a92682f2f94f987e72aa8cfbabd23 324 Gene3D G3DSA:3.40.50.10490 189 321 1.6E-28 T 10-11-2016 A4G23_RS12035 588a92682f2f94f987e72aa8cfbabd23 324 SUPERFAMILY SSF53697 55 321 6.01E-42 T 10-11-2016 A4G23_RS12035 588a92682f2f94f987e72aa8cfbabd23 324 Gene3D G3DSA:3.40.50.10490 4 173 8.6E-15 T 10-11-2016 A4G23_RS21820 9adfa5f09d736be0602cdb7ac0afe1f4 267 PIRSF PIRSF006648 3 267 7.0E-77 T 10-11-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 A4G23_RS21820 9adfa5f09d736be0602cdb7ac0afe1f4 267 Pfam PF01061 ABC-2 type transporter 24 230 7.1E-32 T 10-11-2016 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A4G23_RS19435 4bb43cb618e77507367caeef59c292fa 322 Gene3D G3DSA:3.40.50.300 77 310 6.9E-16 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS19435 4bb43cb618e77507367caeef59c292fa 322 SUPERFAMILY SSF52540 77 311 8.86E-18 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS19435 4bb43cb618e77507367caeef59c292fa 322 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 80 235 1.5E-5 T 10-11-2016 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A4G23_RS08280 af70df1a37a21b1965a83aa02544fd4b 117 Pfam PF14017 Protein of unknown function (DUF4233) 2 105 4.1E-33 T 10-11-2016 IPR025327 Protein of unknown function DUF4233 A4G23_RS25115 b495e20a6abae998b50493167b1949c3 380 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 105 119 - T 10-11-2016 IPR000092 Polyprenyl synthetase GO:0008299 A4G23_RS25115 b495e20a6abae998b50493167b1949c3 380 Gene3D G3DSA:1.10.600.10 25 367 1.8E-68 T 10-11-2016 IPR008949 Isoprenoid synthase domain A4G23_RS25115 b495e20a6abae998b50493167b1949c3 380 SUPERFAMILY SSF48576 33 365 2.26E-62 T 10-11-2016 IPR008949 Isoprenoid synthase domain A4G23_RS25115 b495e20a6abae998b50493167b1949c3 380 Pfam PF00348 Polyprenyl synthetase 58 308 3.9E-40 T 10-11-2016 IPR000092 Polyprenyl synthetase GO:0008299 A4G23_RS04180 e200c856796d4fb1f664ea63b3c0d0b6 489 PIRSF PIRSF006060 22 487 2.3E-64 T 10-11-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A4G23_RS04180 e200c856796d4fb1f664ea63b3c0d0b6 489 TIGRFAM TIGR00908 2A0305: ethanolamine permease 28 475 4.8E-148 T 10-11-2016 IPR004757 Ethanolamine permease A4G23_RS04180 e200c856796d4fb1f664ea63b3c0d0b6 489 Pfam PF13520 Amino acid permease 38 444 2.2E-38 T 10-11-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A4G23_RS01955 674b35d57b2c3a2f1b91d8320dfbf133 237 Gene3D G3DSA:3.40.1130.10 29 205 1.3E-25 T 10-11-2016 A4G23_RS01955 674b35d57b2c3a2f1b91d8320dfbf133 237 SUPERFAMILY SSF69593 17 205 1.57E-39 T 10-11-2016 A4G23_RS01955 674b35d57b2c3a2f1b91d8320dfbf133 237 SMART SM00563 38 152 1.3E-37 T 10-11-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 A4G23_RS01955 674b35d57b2c3a2f1b91d8320dfbf133 237 Pfam PF01553 Acyltransferase 23 149 4.4E-30 T 10-11-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 A4G23_RS19075 6dc4373ab30c2595bfeaa879533c17d2 345 SUPERFAMILY SSF48576 58 344 8.96E-72 T 10-11-2016 IPR008949 Isoprenoid synthase domain A4G23_RS19075 6dc4373ab30c2595bfeaa879533c17d2 345 Pfam PF00348 Polyprenyl synthetase 59 283 2.7E-57 T 10-11-2016 IPR000092 Polyprenyl synthetase GO:0008299 A4G23_RS19075 6dc4373ab30c2595bfeaa879533c17d2 345 Gene3D G3DSA:1.10.600.10 13 344 6.5E-82 T 10-11-2016 IPR008949 Isoprenoid synthase domain A4G23_RS19075 6dc4373ab30c2595bfeaa879533c17d2 345 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 97 111 - T 10-11-2016 IPR000092 Polyprenyl synthetase GO:0008299 A4G23_RS00115 7de0bd659935b1add12f998466f559b7 609 Gene3D G3DSA:3.40.50.300 212 388 9.6E-27 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS00115 7de0bd659935b1add12f998466f559b7 609 Gene3D G3DSA:3.40.50.300 2 165 9.6E-27 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS00115 7de0bd659935b1add12f998466f559b7 609 SUPERFAMILY SSF52540 4 161 3.89E-18 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS00115 7de0bd659935b1add12f998466f559b7 609 SUPERFAMILY SSF52540 212 383 3.89E-18 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS27325 7de0bd659935b1add12f998466f559b7 609 Gene3D G3DSA:3.40.50.300 212 388 9.6E-27 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS27325 7de0bd659935b1add12f998466f559b7 609 Gene3D G3DSA:3.40.50.300 2 165 9.6E-27 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS27325 7de0bd659935b1add12f998466f559b7 609 SUPERFAMILY SSF52540 4 161 3.89E-18 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS27325 7de0bd659935b1add12f998466f559b7 609 SUPERFAMILY SSF52540 212 383 3.89E-18 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS11990 2646808b4cf53a4dc71a6590c55f78d5 67 SMART SM00357 3 66 1.0E-30 T 10-11-2016 IPR011129 Cold shock protein GO:0003676 A4G23_RS11990 2646808b4cf53a4dc71a6590c55f78d5 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 10-11-2016 IPR019844 Cold-shock conserved site A4G23_RS11990 2646808b4cf53a4dc71a6590c55f78d5 67 PIRSF PIRSF002599 1 67 9.7E-26 T 10-11-2016 IPR012156 Cold shock, CspA GO:0003676 A4G23_RS11990 2646808b4cf53a4dc71a6590c55f78d5 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 64 7.7E-31 T 10-11-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4G23_RS11990 2646808b4cf53a4dc71a6590c55f78d5 67 Gene3D G3DSA:2.40.50.140 1 65 1.6E-32 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS11990 2646808b4cf53a4dc71a6590c55f78d5 67 PRINTS PR00050 Cold shock protein signature 4 19 1.2E-19 T 10-11-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4G23_RS11990 2646808b4cf53a4dc71a6590c55f78d5 67 PRINTS PR00050 Cold shock protein signature 39 57 1.2E-19 T 10-11-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4G23_RS11990 2646808b4cf53a4dc71a6590c55f78d5 67 PRINTS PR00050 Cold shock protein signature 24 33 1.2E-19 T 10-11-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4G23_RS11990 2646808b4cf53a4dc71a6590c55f78d5 67 SUPERFAMILY SSF50249 1 64 1.03E-24 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS01570 4ad2689ffb444bcd56ce1431ae896515 132 Pfam PF14534 Domain of unknown function (DUF4440) 22 115 7.4E-7 T 10-11-2016 IPR027843 Domain of unknown function DUF4440 A4G23_RS01570 4ad2689ffb444bcd56ce1431ae896515 132 SUPERFAMILY SSF54427 21 128 1.93E-10 T 10-11-2016 IPR032710 NTF2-like domain A4G23_RS11485 fec9d9e325092de9e4574ec2ba6f40bd 288 PRINTS PR00412 Epoxide hydrolase signature 260 282 3.2E-10 T 10-11-2016 IPR000639 Epoxide hydrolase-like GO:0003824 A4G23_RS11485 fec9d9e325092de9e4574ec2ba6f40bd 288 PRINTS PR00412 Epoxide hydrolase signature 61 76 3.2E-10 T 10-11-2016 IPR000639 Epoxide hydrolase-like GO:0003824 A4G23_RS11485 fec9d9e325092de9e4574ec2ba6f40bd 288 PRINTS PR00412 Epoxide hydrolase signature 106 119 3.2E-10 T 10-11-2016 IPR000639 Epoxide hydrolase-like GO:0003824 A4G23_RS11485 fec9d9e325092de9e4574ec2ba6f40bd 288 PRINTS PR00412 Epoxide hydrolase signature 120 133 3.2E-10 T 10-11-2016 IPR000639 Epoxide hydrolase-like GO:0003824 A4G23_RS11485 fec9d9e325092de9e4574ec2ba6f40bd 288 Gene3D G3DSA:3.40.50.1820 6 285 4.7E-60 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS11485 fec9d9e325092de9e4574ec2ba6f40bd 288 Pfam PF12697 Alpha/beta hydrolase family 38 277 9.0E-23 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS11485 fec9d9e325092de9e4574ec2ba6f40bd 288 PRINTS PR00111 Alpha/beta hydrolase fold signature 230 244 2.8E-8 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS11485 fec9d9e325092de9e4574ec2ba6f40bd 288 PRINTS PR00111 Alpha/beta hydrolase fold signature 61 76 2.8E-8 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS11485 fec9d9e325092de9e4574ec2ba6f40bd 288 PRINTS PR00111 Alpha/beta hydrolase fold signature 106 119 2.8E-8 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS11485 fec9d9e325092de9e4574ec2ba6f40bd 288 PRINTS PR00111 Alpha/beta hydrolase fold signature 120 133 2.8E-8 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS11485 fec9d9e325092de9e4574ec2ba6f40bd 288 SUPERFAMILY SSF53474 10 283 8.73E-54 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS19380 62ed8d168593d653e77733ea8433d76f 472 SUPERFAMILY SSF48371 268 417 3.7E-14 T 10-11-2016 IPR016024 Armadillo-type fold GO:0005488 A4G23_RS19380 62ed8d168593d653e77733ea8433d76f 472 SUPERFAMILY SSF48371 184 227 3.7E-14 T 10-11-2016 IPR016024 Armadillo-type fold GO:0005488 A4G23_RS19380 62ed8d168593d653e77733ea8433d76f 472 SUPERFAMILY SSF48371 75 142 3.7E-14 T 10-11-2016 IPR016024 Armadillo-type fold GO:0005488 A4G23_RS19380 62ed8d168593d653e77733ea8433d76f 472 Gene3D G3DSA:1.25.10.10 175 434 7.3E-16 T 10-11-2016 IPR011989 Armadillo-like helical A4G23_RS16695 9c5c97221b14498eb9a9b06f60a6fd9c 60 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 1 58 19.034 T 10-11-2016 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 A4G23_RS16695 9c5c97221b14498eb9a9b06f60a6fd9c 60 Pfam PF00327 Ribosomal protein L30p/L7e 4 54 1.6E-16 T 10-11-2016 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain A4G23_RS16695 9c5c97221b14498eb9a9b06f60a6fd9c 60 Gene3D G3DSA:3.30.1390.20 1 59 5.6E-27 T 10-11-2016 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain A4G23_RS16695 9c5c97221b14498eb9a9b06f60a6fd9c 60 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 4 58 3.7E-27 T 10-11-2016 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 A4G23_RS16695 9c5c97221b14498eb9a9b06f60a6fd9c 60 SUPERFAMILY SSF55129 1 60 1.02E-20 T 10-11-2016 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain A4G23_RS16695 9c5c97221b14498eb9a9b06f60a6fd9c 60 ProSitePatterns PS00634 Ribosomal protein L30 signature. 22 54 - T 10-11-2016 IPR018038 Ribosomal protein L30, conserved site A4G23_RS16695 9c5c97221b14498eb9a9b06f60a6fd9c 60 PIRSF PIRSF002211 1 60 5.0E-28 T 10-11-2016 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 A4G23_RS01755 c8f17c51c7dc9c151723563ebdb5b1ac 525 Gene3D G3DSA:2.60.60.30 340 450 2.5E-5 T 10-11-2016 A4G23_RS01755 c8f17c51c7dc9c151723563ebdb5b1ac 525 Gene3D G3DSA:2.60.60.30 13 164 6.4E-34 T 10-11-2016 A4G23_RS01755 c8f17c51c7dc9c151723563ebdb5b1ac 525 Pfam PF02342 TerD domain 3 166 4.5E-44 T 10-11-2016 IPR003325 TerD domain GO:0006950 A4G23_RS08480 31815c53edd0098ba0e92b336bdb6160 557 SUPERFAMILY SSF49899 140 310 7.52E-20 T 10-11-2016 IPR013320 Concanavalin A-like lectin/glucanase domain A4G23_RS08480 31815c53edd0098ba0e92b336bdb6160 557 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 141 308 2.7E-22 T 10-11-2016 A4G23_RS08480 31815c53edd0098ba0e92b336bdb6160 557 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 368 546 1.7E-11 T 10-11-2016 A4G23_RS08480 31815c53edd0098ba0e92b336bdb6160 557 SMART SM00560 385 546 8.2E-11 T 10-11-2016 IPR006558 LamG-like jellyroll fold A4G23_RS08480 31815c53edd0098ba0e92b336bdb6160 557 SMART SM00560 153 305 2.3E-22 T 10-11-2016 IPR006558 LamG-like jellyroll fold A4G23_RS08480 31815c53edd0098ba0e92b336bdb6160 557 Gene3D G3DSA:2.60.120.200 361 551 7.9E-17 T 10-11-2016 IPR013320 Concanavalin A-like lectin/glucanase domain A4G23_RS08480 31815c53edd0098ba0e92b336bdb6160 557 Gene3D G3DSA:2.60.120.200 122 310 1.3E-23 T 10-11-2016 IPR013320 Concanavalin A-like lectin/glucanase domain A4G23_RS08480 31815c53edd0098ba0e92b336bdb6160 557 SUPERFAMILY SSF49899 354 550 4.12E-14 T 10-11-2016 IPR013320 Concanavalin A-like lectin/glucanase domain A4G23_RS18830 f62c9726a1ca66a2f01c48328249a6e5 171 Gene3D G3DSA:3.90.79.10 43 156 8.0E-17 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS18830 f62c9726a1ca66a2f01c48328249a6e5 171 SUPERFAMILY SSF55811 17 159 1.02E-19 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS18830 f62c9726a1ca66a2f01c48328249a6e5 171 Pfam PF00293 NUDIX domain 43 152 6.4E-11 T 10-11-2016 IPR000086 NUDIX hydrolase domain GO:0016787 A4G23_RS22115 dd6f5a1de2112360564bca7e5ecdc75e 118 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 113 1.7E-8 T 10-11-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4G23_RS22115 dd6f5a1de2112360564bca7e5ecdc75e 118 Gene3D G3DSA:3.10.180.10 3 116 1.1E-20 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS22115 dd6f5a1de2112360564bca7e5ecdc75e 118 SUPERFAMILY SSF54593 7 117 2.28E-18 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS25015 bd16e82a756123519724c08741917a7b 494 Pfam PF00361 Proton-conducting membrane transporter 127 404 2.5E-50 T 10-11-2016 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS25015 bd16e82a756123519724c08741917a7b 494 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 131 150 1.2E-11 T 10-11-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS25015 bd16e82a756123519724c08741917a7b 494 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 230 254 1.2E-11 T 10-11-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS25015 bd16e82a756123519724c08741917a7b 494 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 161 185 1.2E-11 T 10-11-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS25015 bd16e82a756123519724c08741917a7b 494 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 368 394 1.2E-11 T 10-11-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS25015 bd16e82a756123519724c08741917a7b 494 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 316 335 1.2E-11 T 10-11-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS17410 c58c4411108966fcf75fb6da4ce5aef7 272 Gene3D G3DSA:3.75.10.10 9 269 2.2E-58 T 10-11-2016 A4G23_RS17410 c58c4411108966fcf75fb6da4ce5aef7 272 Pfam PF02274 Amidinotransferase 14 269 5.0E-12 T 10-11-2016 A4G23_RS17410 c58c4411108966fcf75fb6da4ce5aef7 272 SUPERFAMILY SSF55909 10 270 2.55E-50 T 10-11-2016 A4G23_RS19895 ab5089e1f91402ab2767e72bb956d679 168 Pfam PF13581 Histidine kinase-like ATPase domain 47 157 6.6E-12 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS19895 ab5089e1f91402ab2767e72bb956d679 168 SUPERFAMILY SSF55874 73 160 8.58E-10 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS08200 998492f5582807cceeb56a8da88f1145 321 Gene3D G3DSA:3.40.50.720 1 118 5.0E-23 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS08200 998492f5582807cceeb56a8da88f1145 321 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 2 105 3.5E-14 T 10-11-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 A4G23_RS08200 998492f5582807cceeb56a8da88f1145 321 Gene3D G3DSA:3.30.360.10 119 227 2.7E-28 T 10-11-2016 A4G23_RS08200 998492f5582807cceeb56a8da88f1145 321 Gene3D G3DSA:3.30.360.10 262 316 2.7E-28 T 10-11-2016 A4G23_RS08200 998492f5582807cceeb56a8da88f1145 321 SUPERFAMILY SSF51735 1 131 1.67E-29 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS08200 998492f5582807cceeb56a8da88f1145 321 SUPERFAMILY SSF55347 110 228 6.05E-18 T 10-11-2016 A4G23_RS08200 998492f5582807cceeb56a8da88f1145 321 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 119 198 6.4E-5 T 10-11-2016 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 A4G23_RS04565 f1ffcc05df7f5c03587af5f70a40a092 257 Gene3D G3DSA:3.40.50.720 5 209 3.8E-43 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS04565 f1ffcc05df7f5c03587af5f70a40a092 257 Pfam PF00106 short chain dehydrogenase 12 188 1.9E-33 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS04565 f1ffcc05df7f5c03587af5f70a40a092 257 SUPERFAMILY SSF51735 7 248 1.35E-47 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS04565 f1ffcc05df7f5c03587af5f70a40a092 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 5.6E-20 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS04565 f1ffcc05df7f5c03587af5f70a40a092 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 5.6E-20 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS04565 f1ffcc05df7f5c03587af5f70a40a092 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 5.6E-20 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS04565 f1ffcc05df7f5c03587af5f70a40a092 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 5.6E-20 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS04565 f1ffcc05df7f5c03587af5f70a40a092 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 5.6E-20 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS04565 f1ffcc05df7f5c03587af5f70a40a092 257 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 134 162 - T 10-11-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4G23_RS16190 e8e8aa53c14eb97ab9beeb001411b11a 200 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 50 159 1.7E-24 T 10-11-2016 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16190 e8e8aa53c14eb97ab9beeb001411b11a 200 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 2 164 40.483 T 10-11-2016 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16190 e8e8aa53c14eb97ab9beeb001411b11a 200 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 29 165 6.2E-67 T 10-11-2016 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16190 e8e8aa53c14eb97ab9beeb001411b11a 200 Gene3D G3DSA:3.40.50.700 33 165 2.0E-37 T 10-11-2016 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16190 e8e8aa53c14eb97ab9beeb001411b11a 200 SUPERFAMILY SSF56770 28 168 2.62E-62 T 10-11-2016 A4G23_RS23360 35d3e24b987710841cbf472a4dff3619 215 SUPERFAMILY SSF53271 2 207 2.56E-58 T 10-11-2016 IPR029057 Phosphoribosyltransferase-like A4G23_RS23360 35d3e24b987710841cbf472a4dff3619 215 Pfam PF14681 Uracil phosphoribosyltransferase 5 208 1.5E-69 T 10-11-2016 IPR029057 Phosphoribosyltransferase-like A4G23_RS23360 35d3e24b987710841cbf472a4dff3619 215 Gene3D G3DSA:3.40.50.2020 1 209 4.3E-86 T 10-11-2016 IPR029057 Phosphoribosyltransferase-like A4G23_RS10915 b4fa9e1c609c3bded251c49e660b55ca 278 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 7 252 4.8E-91 T 10-11-2016 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112 A4G23_RS10915 b4fa9e1c609c3bded251c49e660b55ca 278 Pfam PF01048 Phosphorylase superfamily 7 250 2.8E-41 T 10-11-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A4G23_RS10915 b4fa9e1c609c3bded251c49e660b55ca 278 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 5 273 42.117 T 10-11-2016 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112 A4G23_RS10915 b4fa9e1c609c3bded251c49e660b55ca 278 Gene3D G3DSA:3.40.50.1580 3 269 1.5E-86 T 10-11-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A4G23_RS10915 b4fa9e1c609c3bded251c49e660b55ca 278 SUPERFAMILY SSF53167 5 270 2.67E-84 T 10-11-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A4G23_RS18590 419a5d79c8e484ee00053ba7af1fab0d 210 Pfam PF06210 Protein of unknown function (DUF1003) 76 177 2.2E-40 T 10-11-2016 IPR010406 Protein of unknown function DUF1003 A4G23_RS14120 43d8e733f77f91d6a68b7b27a52a1768 231 Pfam PF07366 SnoaL-like polyketide cyclase 102 226 4.8E-25 T 10-11-2016 IPR009959 Polyketide cyclase SnoaL-like domain A4G23_RS14120 43d8e733f77f91d6a68b7b27a52a1768 231 Gene3D G3DSA:3.10.450.50 99 229 4.8E-36 T 10-11-2016 IPR032710 NTF2-like domain A4G23_RS14120 43d8e733f77f91d6a68b7b27a52a1768 231 SUPERFAMILY SSF54427 99 229 3.33E-32 T 10-11-2016 IPR032710 NTF2-like domain A4G23_RS24895 1cdf426adb6c987745836f7c2b1d29ae 316 Gene3D G3DSA:1.10.600.10 13 309 1.8E-81 T 10-11-2016 IPR008949 Isoprenoid synthase domain A4G23_RS24895 1cdf426adb6c987745836f7c2b1d29ae 316 ProSitePatterns PS01044 Squalene and phytoene synthases signature 1. 141 156 - T 10-11-2016 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A4G23_RS24895 1cdf426adb6c987745836f7c2b1d29ae 316 TIGRFAM TIGR03465 HpnD: squalene synthase HpnD 26 298 3.9E-92 T 10-11-2016 IPR017828 Squalene/phytoene synthase HpnD GO:0016117|GO:0016767 A4G23_RS24895 1cdf426adb6c987745836f7c2b1d29ae 316 ProSitePatterns PS01045 Squalene and phytoene synthases signature 2. 176 201 - T 10-11-2016 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A4G23_RS24895 1cdf426adb6c987745836f7c2b1d29ae 316 SUPERFAMILY SSF48576 18 304 4.32E-74 T 10-11-2016 IPR008949 Isoprenoid synthase domain A4G23_RS24895 1cdf426adb6c987745836f7c2b1d29ae 316 Pfam PF00494 Squalene/phytoene synthase 28 287 1.1E-72 T 10-11-2016 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 A4G23_RS19885 6918569bcea9af6b11723c1412da10a0 420 Gene3D G3DSA:2.40.440.10 267 395 4.1E-19 T 10-11-2016 A4G23_RS19885 6918569bcea9af6b11723c1412da10a0 420 SUPERFAMILY SSF141523 267 394 1.57E-22 T 10-11-2016 A4G23_RS19885 6918569bcea9af6b11723c1412da10a0 420 Pfam PF03734 L,D-transpeptidase catalytic domain 265 394 4.9E-13 T 10-11-2016 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 A4G23_RS11420 3e7f77e7a32aeb3f45a93b4426b46488 151 SUPERFAMILY SSF55874 28 121 1.44E-5 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS11420 3e7f77e7a32aeb3f45a93b4426b46488 151 Pfam PF13581 Histidine kinase-like ATPase domain 5 115 2.7E-9 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS21460 3781dc654257d9f83e547b3b5cfd5b29 257 Gene3D G3DSA:3.10.180.10 139 252 5.1E-25 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS21460 3781dc654257d9f83e547b3b5cfd5b29 257 Gene3D G3DSA:3.10.180.10 11 125 6.3E-31 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS21460 3781dc654257d9f83e547b3b5cfd5b29 257 SUPERFAMILY SSF54593 141 251 1.75E-17 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS21460 3781dc654257d9f83e547b3b5cfd5b29 257 SUPERFAMILY SSF54593 12 122 1.02E-17 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS06005 60e53c4bab739531e2b8464e9633cba7 150 Pfam PF10825 Protein of unknown function (DUF2752) 56 104 2.3E-16 T 10-11-2016 IPR021215 Protein of unknown function DUF2752 A4G23_RS15450 b7b9c08f80626e38b4a3246fb15a6a51 235 Gene3D G3DSA:3.40.50.2300 3 121 1.3E-40 T 10-11-2016 A4G23_RS15450 b7b9c08f80626e38b4a3246fb15a6a51 235 Gene3D G3DSA:1.10.10.10 141 234 2.0E-31 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS15450 b7b9c08f80626e38b4a3246fb15a6a51 235 SMART SM00448 4 114 7.4E-42 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS15450 b7b9c08f80626e38b4a3246fb15a6a51 235 SMART SM00862 162 233 7.3E-26 T 10-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4G23_RS15450 b7b9c08f80626e38b4a3246fb15a6a51 235 Pfam PF00072 Response regulator receiver domain 6 115 1.8E-28 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS15450 b7b9c08f80626e38b4a3246fb15a6a51 235 SUPERFAMILY SSF52172 3 122 8.82E-41 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS15450 b7b9c08f80626e38b4a3246fb15a6a51 235 SUPERFAMILY SSF46894 136 234 3.97E-28 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS15450 b7b9c08f80626e38b4a3246fb15a6a51 235 Pfam PF00486 Transcriptional regulatory protein, C terminal 162 233 1.6E-23 T 10-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4G23_RS03925 4dee099c6ed44d8fc0ccf99f2e8ef635 285 Pfam PF03180 NLPA lipoprotein 45 281 9.0E-92 T 10-11-2016 IPR004872 Lipoprotein NlpA family A4G23_RS03925 4dee099c6ed44d8fc0ccf99f2e8ef635 285 PIRSF PIRSF002854 2 282 3.4E-104 T 10-11-2016 IPR004872 Lipoprotein NlpA family A4G23_RS03925 4dee099c6ed44d8fc0ccf99f2e8ef635 285 SUPERFAMILY SSF53850 45 281 2.86E-81 T 10-11-2016 A4G23_RS03925 4dee099c6ed44d8fc0ccf99f2e8ef635 285 Gene3D G3DSA:3.40.190.10 42 174 3.1E-55 T 10-11-2016 A4G23_RS06130 b3ba1aa652675a5ab66f980a62b19d58 271 Gene3D G3DSA:3.40.30.10 84 270 1.0E-26 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS06130 b3ba1aa652675a5ab66f980a62b19d58 271 Pfam PF13462 Thioredoxin 82 266 1.6E-38 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS06130 b3ba1aa652675a5ab66f980a62b19d58 271 SUPERFAMILY SSF52833 80 249 8.0E-19 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS01290 2048bbfcd8edbf9258218e57a6a27d87 120 Pfam PF05331 Protein of unknown function (DUF742) 11 120 9.9E-37 T 10-11-2016 IPR007995 Protein of unknown function DUF742 A4G23_RS13930 4621fd1ec260d24092282a7f36420f28 522 Pfam PF07690 Major Facilitator Superfamily 34 429 6.0E-47 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS13930 4621fd1ec260d24092282a7f36420f28 522 Gene3D G3DSA:1.20.1250.20 34 203 9.6E-30 T 10-11-2016 A4G23_RS13930 4621fd1ec260d24092282a7f36420f28 522 Gene3D G3DSA:1.20.1250.20 282 451 4.1E-20 T 10-11-2016 A4G23_RS13930 4621fd1ec260d24092282a7f36420f28 522 Gene3D G3DSA:1.20.1250.20 494 518 4.1E-20 T 10-11-2016 A4G23_RS13930 4621fd1ec260d24092282a7f36420f28 522 PRINTS PR01036 Tetracycline resistance protein TetB signature 420 439 6.7E-11 T 10-11-2016 A4G23_RS13930 4621fd1ec260d24092282a7f36420f28 522 PRINTS PR01036 Tetracycline resistance protein TetB signature 154 178 6.7E-11 T 10-11-2016 A4G23_RS13930 4621fd1ec260d24092282a7f36420f28 522 PRINTS PR01036 Tetracycline resistance protein TetB signature 124 144 6.7E-11 T 10-11-2016 A4G23_RS13930 4621fd1ec260d24092282a7f36420f28 522 PRINTS PR01036 Tetracycline resistance protein TetB signature 33 57 6.7E-11 T 10-11-2016 A4G23_RS13930 4621fd1ec260d24092282a7f36420f28 522 SUPERFAMILY SSF103473 8 218 1.23E-65 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS13930 4621fd1ec260d24092282a7f36420f28 522 SUPERFAMILY SSF103473 487 513 1.23E-65 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS13930 4621fd1ec260d24092282a7f36420f28 522 SUPERFAMILY SSF103473 267 439 1.23E-65 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS15615 74cb71de54dd2d31f416b408302fc31b 93 Gene3D G3DSA:3.40.30.10 17 90 6.5E-27 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS15615 74cb71de54dd2d31f416b408302fc31b 93 SUPERFAMILY SSF52833 13 90 6.87E-18 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS15615 74cb71de54dd2d31f416b408302fc31b 93 Pfam PF05768 Glutaredoxin-like domain (DUF836) 17 90 3.8E-19 T 10-11-2016 IPR008554 Glutaredoxin-like A4G23_RS18900 27f26f43cf5f111efa8d3f08ce6afa3f 107 Pfam PF00893 Small Multidrug Resistance protein 1 93 4.9E-24 T 10-11-2016 IPR000390 Small multidrug resistance protein family GO:0016021 A4G23_RS18900 27f26f43cf5f111efa8d3f08ce6afa3f 107 SUPERFAMILY SSF103481 6 105 3.66E-18 T 10-11-2016 A4G23_RS06630 adadd5966f6b56a456ac0db4f4e053dc 261 Pfam PF04012 PspA/IM30 family 2 224 2.5E-28 T 10-11-2016 IPR007157 PspA/IM30 A4G23_RS12290 fa66fc982a66b16c59d5ba931a7b2dfd 133 SMART SM00530 12 67 9.9E-16 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS12290 fa66fc982a66b16c59d5ba931a7b2dfd 133 Pfam PF01381 Helix-turn-helix 13 65 1.4E-14 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS12290 fa66fc982a66b16c59d5ba931a7b2dfd 133 Gene3D G3DSA:1.10.260.40 8 108 8.6E-22 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS12290 fa66fc982a66b16c59d5ba931a7b2dfd 133 SUPERFAMILY SSF47413 8 69 8.31E-17 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS22540 ec938c5fa989772d652bd653a9132434 209 SUPERFAMILY SSF55729 24 47 8.06E-25 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS22540 ec938c5fa989772d652bd653a9132434 209 SUPERFAMILY SSF55729 77 207 8.06E-25 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS22540 ec938c5fa989772d652bd653a9132434 209 Pfam PF00583 Acetyltransferase (GNAT) family 105 182 5.5E-16 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS22540 ec938c5fa989772d652bd653a9132434 209 Gene3D G3DSA:3.40.630.30 78 208 5.6E-29 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS13840 c75fc387bba9d05dbb947dc2c442551c 237 SMART SM00943 25 221 2.8E-21 T 10-11-2016 IPR015330 DNA primase/polymerase, bifunctional, N-terminal A4G23_RS13840 c75fc387bba9d05dbb947dc2c442551c 237 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 25 206 7.8E-18 T 10-11-2016 IPR015330 DNA primase/polymerase, bifunctional, N-terminal A4G23_RS10370 f38991b4312a7f6ed7401f096cb126f3 308 Gene3D G3DSA:3.30.420.150 129 301 7.2E-61 T 10-11-2016 A4G23_RS10370 f38991b4312a7f6ed7401f096cb126f3 308 SUPERFAMILY SSF53067 3 125 1.04E-31 T 10-11-2016 A4G23_RS10370 f38991b4312a7f6ed7401f096cb126f3 308 Gene3D G3DSA:3.30.420.40 1 125 4.4E-48 T 10-11-2016 A4G23_RS10370 f38991b4312a7f6ed7401f096cb126f3 308 Pfam PF02541 Ppx/GppA phosphatase family 24 294 2.6E-61 T 10-11-2016 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 A4G23_RS10370 f38991b4312a7f6ed7401f096cb126f3 308 SUPERFAMILY SSF53067 130 301 6.35E-41 T 10-11-2016 A4G23_RS08960 5fe06b0b79346040cb8e2402293e1549 200 SUPERFAMILY SSF48498 82 167 1.4E-7 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS08960 5fe06b0b79346040cb8e2402293e1549 200 Gene3D G3DSA:1.10.357.10 61 166 9.2E-24 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS08960 5fe06b0b79346040cb8e2402293e1549 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 4.9E-9 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS08960 5fe06b0b79346040cb8e2402293e1549 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 4.9E-9 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS08960 5fe06b0b79346040cb8e2402293e1549 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 2.9E-16 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS08960 5fe06b0b79346040cb8e2402293e1549 200 Gene3D G3DSA:1.10.10.60 3 60 2.8E-20 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS08960 5fe06b0b79346040cb8e2402293e1549 200 SUPERFAMILY SSF46689 2 71 2.1E-17 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS01035 8f7c6295cb9d00b844ee0f75d50800c9 335 Gene3D G3DSA:3.40.50.2000 165 332 6.2E-56 T 10-11-2016 A4G23_RS01035 8f7c6295cb9d00b844ee0f75d50800c9 335 Gene3D G3DSA:3.40.50.2000 1 153 1.1E-20 T 10-11-2016 A4G23_RS01035 8f7c6295cb9d00b844ee0f75d50800c9 335 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 74 308 1.1E-25 T 10-11-2016 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 A4G23_RS01035 8f7c6295cb9d00b844ee0f75d50800c9 335 SUPERFAMILY SSF53756 1 332 6.59E-72 T 10-11-2016 A4G23_RS16465 a426b39a75b8edc3b3969cc917c6628c 65 Gene3D G3DSA:1.10.10.10 15 59 2.3E-4 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS16465 a426b39a75b8edc3b3969cc917c6628c 65 SUPERFAMILY SSF46955 12 57 3.53E-6 T 10-11-2016 IPR009061 Putative DNA-binding domain A4G23_RS04700 84a06a8df38ed5d8a1ffc893883158f5 408 Gene3D G3DSA:3.40.50.10540 15 227 5.7E-97 T 10-11-2016 IPR023606 CoA-transferase family III domain A4G23_RS04700 84a06a8df38ed5d8a1ffc893883158f5 408 Gene3D G3DSA:3.40.50.10540 318 407 5.7E-97 T 10-11-2016 IPR023606 CoA-transferase family III domain A4G23_RS04700 84a06a8df38ed5d8a1ffc893883158f5 408 Gene3D G3DSA:3.30.1540.10 233 317 6.0E-28 T 10-11-2016 A4G23_RS04700 84a06a8df38ed5d8a1ffc893883158f5 408 Pfam PF02515 CoA-transferase family III 18 384 3.3E-111 T 10-11-2016 IPR003673 CoA-transferase family III GO:0003824 A4G23_RS04700 84a06a8df38ed5d8a1ffc893883158f5 408 SUPERFAMILY SSF89796 13 407 3.14E-122 T 10-11-2016 IPR023606 CoA-transferase family III domain A4G23_RS06925 719b15df18d391d6f3d91da90a7a7ddf 206 Pfam PF06197 Protein of unknown function (DUF998) 4 206 2.4E-28 T 10-11-2016 IPR009339 Protein of unknown function DUF998 A4G23_RS07275 6f04a63df3efddabdb2e15a3c44da7cb 156 Pfam PF07681 DoxX 22 101 1.7E-10 T 10-11-2016 IPR032808 DoxX family A4G23_RS19700 6c2d7b7bbfa5de4b71e734c755027b19 264 SUPERFAMILY SSF51219 19 212 4.97E-29 T 10-11-2016 IPR016031 Tryptophan RNA-binding attenuator protein-like domain A4G23_RS19700 6c2d7b7bbfa5de4b71e734c755027b19 264 Pfam PF01987 Mitochondrial biogenesis AIM24 29 210 9.7E-10 T 10-11-2016 IPR002838 Mitochondrial biogenesis protein AIM24 A4G23_RS19700 6c2d7b7bbfa5de4b71e734c755027b19 264 Gene3D G3DSA:3.60.160.10 21 211 2.3E-22 T 10-11-2016 IPR002838 Mitochondrial biogenesis protein AIM24 A4G23_RS14150 8be3296c48a71eba27db68e37bea6eec 148 Pfam PF01951 Archease protein family (MTH1598/TM1083) 16 148 1.7E-24 T 10-11-2016 IPR023572 Archease domain Reactome: R-HSA-6784531 A4G23_RS14150 8be3296c48a71eba27db68e37bea6eec 148 Gene3D G3DSA:3.55.10.10 16 148 9.8E-21 T 10-11-2016 IPR023572 Archease domain Reactome: R-HSA-6784531 A4G23_RS14150 8be3296c48a71eba27db68e37bea6eec 148 SUPERFAMILY SSF69819 14 148 1.23E-23 T 10-11-2016 IPR023572 Archease domain Reactome: R-HSA-6784531 A4G23_RS04975 da16d8072386669eb4edd5b3640ef530 350 SUPERFAMILY SSF81345 26 344 2.62E-76 T 10-11-2016 IPR029022 ABC transporter, BtuC-like A4G23_RS04975 da16d8072386669eb4edd5b3640ef530 350 Gene3D G3DSA:1.10.3470.10 26 346 2.8E-96 T 10-11-2016 IPR029022 ABC transporter, BtuC-like A4G23_RS04975 da16d8072386669eb4edd5b3640ef530 350 Pfam PF01032 FecCD transport family 37 344 3.7E-88 T 10-11-2016 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 A4G23_RS27135 cc10fb7c1c6a73b458a0a66a24f22d87 294 Gene3D G3DSA:2.40.10.10 194 240 9.7E-7 T 10-11-2016 A4G23_RS27135 cc10fb7c1c6a73b458a0a66a24f22d87 294 SUPERFAMILY SSF50494 21 251 3.53E-15 T 10-11-2016 IPR009003 Peptidase S1, PA clan A4G23_RS27135 cc10fb7c1c6a73b458a0a66a24f22d87 294 Pfam PF13365 Trypsin-like peptidase domain 78 232 1.9E-9 T 10-11-2016 A4G23_RS23450 b4d0f83710e3cb88743bb1fd22dce89e 571 Pfam PF00005 ABC transporter 348 502 3.8E-26 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS23450 b4d0f83710e3cb88743bb1fd22dce89e 571 SUPERFAMILY SSF90123 15 308 1.96E-32 T 10-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A4G23_RS23450 b4d0f83710e3cb88743bb1fd22dce89e 571 Gene3D G3DSA:3.40.50.300 332 563 8.8E-67 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS23450 b4d0f83710e3cb88743bb1fd22dce89e 571 Pfam PF00664 ABC transporter transmembrane region 57 261 5.0E-9 T 10-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A4G23_RS23450 b4d0f83710e3cb88743bb1fd22dce89e 571 SMART SM00382 357 548 1.7E-15 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS23450 b4d0f83710e3cb88743bb1fd22dce89e 571 Gene3D G3DSA:1.20.1560.10 19 307 6.2E-28 T 10-11-2016 A4G23_RS23450 b4d0f83710e3cb88743bb1fd22dce89e 571 SUPERFAMILY SSF52540 325 569 1.47E-70 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS23450 b4d0f83710e3cb88743bb1fd22dce89e 571 ProSitePatterns PS00211 ABC transporters family signature. 474 488 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS10975 ecc3f3c0c7987e3eb3843e3a5dec36f5 253 PIRSF PIRSF006157 1 253 3.0E-80 T 10-11-2016 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA type GO:0008270|GO:0016701|GO:0055114 A4G23_RS10975 ecc3f3c0c7987e3eb3843e3a5dec36f5 253 Gene3D G3DSA:3.40.830.10 1 252 1.5E-80 T 10-11-2016 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 A4G23_RS10975 ecc3f3c0c7987e3eb3843e3a5dec36f5 253 SUPERFAMILY SSF53213 1 253 1.09E-78 T 10-11-2016 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 A4G23_RS10975 ecc3f3c0c7987e3eb3843e3a5dec36f5 253 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 21 228 4.0E-40 T 10-11-2016 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 A4G23_RS17740 06e98d0904e564c9cdb6c95d4cd87767 462 Gene3D G3DSA:1.10.260.40 18 81 1.3E-8 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS17740 06e98d0904e564c9cdb6c95d4cd87767 462 SMART SM00530 25 81 1.2E-6 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS17740 06e98d0904e564c9cdb6c95d4cd87767 462 Pfam PF13560 Helix-turn-helix domain 22 80 1.1E-7 T 10-11-2016 A4G23_RS17740 06e98d0904e564c9cdb6c95d4cd87767 462 SUPERFAMILY SSF47413 21 81 4.15E-8 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS01625 dcbb27af3516fe8a532eca2e8978819f 288 SUPERFAMILY SSF55729 149 278 4.95E-16 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS01625 dcbb27af3516fe8a532eca2e8978819f 288 Gene3D G3DSA:3.40.630.30 149 274 4.7E-16 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS14865 712030a41848cd162e409451545a58a7 318 SUPERFAMILY SSF53474 20 313 1.96E-65 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS14865 712030a41848cd162e409451545a58a7 318 Gene3D G3DSA:3.40.50.1820 14 313 4.5E-71 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS14865 712030a41848cd162e409451545a58a7 318 Pfam PF12697 Alpha/beta hydrolase family 44 303 1.5E-20 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS14865 712030a41848cd162e409451545a58a7 318 PRINTS PR00111 Alpha/beta hydrolase fold signature 126 139 1.1E-5 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS14865 712030a41848cd162e409451545a58a7 318 PRINTS PR00111 Alpha/beta hydrolase fold signature 112 125 1.1E-5 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS14865 712030a41848cd162e409451545a58a7 318 PRINTS PR00111 Alpha/beta hydrolase fold signature 68 83 1.1E-5 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS14865 712030a41848cd162e409451545a58a7 318 PRINTS PR00412 Epoxide hydrolase signature 112 125 1.7E-22 T 10-11-2016 IPR000639 Epoxide hydrolase-like GO:0003824 A4G23_RS14865 712030a41848cd162e409451545a58a7 318 PRINTS PR00412 Epoxide hydrolase signature 48 66 1.7E-22 T 10-11-2016 IPR000639 Epoxide hydrolase-like GO:0003824 A4G23_RS14865 712030a41848cd162e409451545a58a7 318 PRINTS PR00412 Epoxide hydrolase signature 288 310 1.7E-22 T 10-11-2016 IPR000639 Epoxide hydrolase-like GO:0003824 A4G23_RS14865 712030a41848cd162e409451545a58a7 318 PRINTS PR00412 Epoxide hydrolase signature 254 270 1.7E-22 T 10-11-2016 IPR000639 Epoxide hydrolase-like GO:0003824 A4G23_RS14865 712030a41848cd162e409451545a58a7 318 PRINTS PR00412 Epoxide hydrolase signature 126 139 1.7E-22 T 10-11-2016 IPR000639 Epoxide hydrolase-like GO:0003824 A4G23_RS14865 712030a41848cd162e409451545a58a7 318 PRINTS PR00412 Epoxide hydrolase signature 68 83 1.7E-22 T 10-11-2016 IPR000639 Epoxide hydrolase-like GO:0003824 A4G23_RS07535 aee2bfc5f767194fc784606691c8ff45 239 Gene3D G3DSA:3.60.110.10 3 238 7.3E-46 T 10-11-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 A4G23_RS07535 aee2bfc5f767194fc784606691c8ff45 239 Pfam PF00795 Carbon-nitrogen hydrolase 3 236 3.1E-26 T 10-11-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 A4G23_RS07535 aee2bfc5f767194fc784606691c8ff45 239 SUPERFAMILY SSF56317 2 238 6.54E-49 T 10-11-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 A4G23_RS27015 2adab8ce7bb02f8c5ad04616a6bb5c79 153 Gene3D G3DSA:3.30.530.20 3 137 1.3E-9 T 10-11-2016 IPR023393 START-like domain A4G23_RS27015 2adab8ce7bb02f8c5ad04616a6bb5c79 153 SUPERFAMILY SSF55961 1 145 2.04E-25 T 10-11-2016 A4G23_RS27015 2adab8ce7bb02f8c5ad04616a6bb5c79 153 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 10 129 5.1E-17 T 10-11-2016 IPR005031 Coenzyme Q-binding protein COQ10, START domain A4G23_RS03900 8371449cf83691a8bc285e867a44270e 272 Gene3D G3DSA:3.30.1330.30 7 105 1.2E-16 T 10-11-2016 IPR029064 50S ribosomal protein L30e-like A4G23_RS03900 8371449cf83691a8bc285e867a44270e 272 Gene3D G3DSA:3.40.1280.10 118 266 8.4E-51 T 10-11-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A4G23_RS03900 8371449cf83691a8bc285e867a44270e 272 SUPERFAMILY SSF55315 6 105 2.21E-16 T 10-11-2016 IPR029064 50S ribosomal protein L30e-like A4G23_RS03900 8371449cf83691a8bc285e867a44270e 272 Pfam PF00588 SpoU rRNA Methylase family 121 263 4.1E-32 T 10-11-2016 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 A4G23_RS03900 8371449cf83691a8bc285e867a44270e 272 SUPERFAMILY SSF75217 107 266 4.38E-38 T 10-11-2016 IPR029028 Alpha/beta knot methyltransferases A4G23_RS09850 07dd5ce3db074133b70096f8ebbc73e9 345 Pfam PF00156 Phosphoribosyl transferase domain 108 192 4.0E-7 T 10-11-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 A4G23_RS09850 07dd5ce3db074133b70096f8ebbc73e9 345 SUPERFAMILY SSF53271 107 193 9.28E-14 T 10-11-2016 IPR029057 Phosphoribosyltransferase-like A4G23_RS09850 07dd5ce3db074133b70096f8ebbc73e9 345 Gene3D G3DSA:3.40.50.2020 85 193 3.8E-14 T 10-11-2016 IPR029057 Phosphoribosyltransferase-like A4G23_RS05830 ae54e8bed5ff8f9f247090730eafbff3 313 SUPERFAMILY SSF159659 25 278 7.85E-74 T 10-11-2016 A4G23_RS05830 ae54e8bed5ff8f9f247090730eafbff3 313 Pfam PF09754 PAC2 family 35 253 2.3E-38 T 10-11-2016 IPR019151 Proteasome assembly chaperone 2 A4G23_RS05830 ae54e8bed5ff8f9f247090730eafbff3 313 Gene3D G3DSA:1.10.287.100 238 275 1.7E-8 T 10-11-2016 IPR013028 Transcription factor IIA, alpha subunit, N-terminal GO:0006367 A4G23_RS05830 ae54e8bed5ff8f9f247090730eafbff3 313 PIRSF PIRSF028754 12 313 1.0E-107 T 10-11-2016 IPR008492 Protein of unknown function DUF774 A4G23_RS02315 f477ef5976918bef5e66df10ad2d87e5 226 SUPERFAMILY SSF47203 105 216 1.5E-10 T 10-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4G23_RS02315 f477ef5976918bef5e66df10ad2d87e5 226 Gene3D G3DSA:1.20.140.10 108 200 7.6E-7 T 10-11-2016 A4G23_RS13825 a0986199068ba516cbd4ea15e2bf83b6 148 SUPERFAMILY SSF55874 29 128 1.83E-13 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS13825 a0986199068ba516cbd4ea15e2bf83b6 148 Gene3D G3DSA:3.30.565.10 20 127 2.7E-13 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS13825 a0986199068ba516cbd4ea15e2bf83b6 148 Pfam PF13581 Histidine kinase-like ATPase domain 13 131 1.7E-22 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS26295 d27857a9d3d59586c0ba609bbaf7aebd 418 Gene3D G3DSA:1.20.1250.20 17 204 1.7E-18 T 10-11-2016 A4G23_RS26295 d27857a9d3d59586c0ba609bbaf7aebd 418 Pfam PF05977 Transmembrane secretion effector 13 337 1.2E-24 T 10-11-2016 IPR010290 Transmembrane secretion effector A4G23_RS26295 d27857a9d3d59586c0ba609bbaf7aebd 418 SUPERFAMILY SSF103473 17 412 4.05E-34 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS26295 d27857a9d3d59586c0ba609bbaf7aebd 418 PRINTS PR01988 Putative bacilysin exporter bacE signature 23 45 1.2E-5 T 10-11-2016 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A4G23_RS26295 d27857a9d3d59586c0ba609bbaf7aebd 418 PRINTS PR01988 Putative bacilysin exporter bacE signature 152 173 1.2E-5 T 10-11-2016 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A4G23_RS26295 d27857a9d3d59586c0ba609bbaf7aebd 418 PRINTS PR01988 Putative bacilysin exporter bacE signature 59 77 1.2E-5 T 10-11-2016 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A4G23_RS26295 d27857a9d3d59586c0ba609bbaf7aebd 418 PRINTS PR01988 Putative bacilysin exporter bacE signature 359 382 1.2E-5 T 10-11-2016 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A4G23_RS26295 d27857a9d3d59586c0ba609bbaf7aebd 418 PRINTS PR01988 Putative bacilysin exporter bacE signature 179 196 1.2E-5 T 10-11-2016 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A4G23_RS17415 519f85c1074e0767a316a1ac25af871b 474 SUPERFAMILY SSF56059 114 330 1.69E-26 T 10-11-2016 A4G23_RS17415 519f85c1074e0767a316a1ac25af871b 474 Pfam PF13535 ATP-grasp domain 152 299 4.5E-11 T 10-11-2016 A4G23_RS17415 519f85c1074e0767a316a1ac25af871b 474 Gene3D G3DSA:3.30.470.20 108 409 1.3E-20 T 10-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 A4G23_RS07810 92bb1e064a7a9d56e476be1dcf13df23 268 Gene3D G3DSA:3.40.50.300 15 244 8.4E-60 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS07810 92bb1e064a7a9d56e476be1dcf13df23 268 SMART SM00382 45 239 3.3E-14 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS07810 92bb1e064a7a9d56e476be1dcf13df23 268 Pfam PF00005 ABC transporter 36 183 1.1E-25 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS07810 92bb1e064a7a9d56e476be1dcf13df23 268 SUPERFAMILY SSF52540 14 247 7.56E-56 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS23740 376ac3d6fca8bf324ec82ce203b42943 402 SUPERFAMILY SSF103473 2 378 6.93E-57 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS23740 376ac3d6fca8bf324ec82ce203b42943 402 Gene3D G3DSA:1.20.1250.20 199 371 1.9E-20 T 10-11-2016 A4G23_RS23740 376ac3d6fca8bf324ec82ce203b42943 402 Pfam PF07690 Major Facilitator Superfamily 7 340 2.8E-41 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS23740 376ac3d6fca8bf324ec82ce203b42943 402 Gene3D G3DSA:1.20.1250.20 2 181 3.5E-23 T 10-11-2016 A4G23_RS22155 2738ef3c6e4ecd0217d15d185706cd49 179 Gene3D G3DSA:1.20.1250.20 5 170 1.2E-5 T 10-11-2016 A4G23_RS22155 2738ef3c6e4ecd0217d15d185706cd49 179 SUPERFAMILY SSF103473 7 175 2.49E-8 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS26260 0c85d8faabba98201de4c2983bc9618c 193 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 34 41 - T 10-11-2016 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A4G23_RS26260 0c85d8faabba98201de4c2983bc9618c 193 Pfam PF00484 Carbonic anhydrase 30 180 4.9E-43 T 10-11-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A4G23_RS26260 0c85d8faabba98201de4c2983bc9618c 193 SMART SM00947 22 184 3.5E-58 T 10-11-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A4G23_RS26260 0c85d8faabba98201de4c2983bc9618c 193 Gene3D G3DSA:3.40.1050.10 9 191 5.0E-60 T 10-11-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A4G23_RS26260 0c85d8faabba98201de4c2983bc9618c 193 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 78 98 - T 10-11-2016 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A4G23_RS26260 0c85d8faabba98201de4c2983bc9618c 193 SUPERFAMILY SSF53056 4 192 3.53E-54 T 10-11-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A4G23_RS07575 af658c95f865ee7677750dc85118077f 168 Gene3D G3DSA:1.10.10.10 9 153 1.8E-43 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS07575 af658c95f865ee7677750dc85118077f 168 SMART SM00347 39 137 4.2E-25 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS07575 af658c95f865ee7677750dc85118077f 168 Pfam PF01047 MarR family 46 104 5.1E-18 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS07575 af658c95f865ee7677750dc85118077f 168 SUPERFAMILY SSF46785 9 153 2.1E-36 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS07575 af658c95f865ee7677750dc85118077f 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 80 95 3.5E-5 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS07575 af658c95f865ee7677750dc85118077f 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 99 115 3.5E-5 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS07575 af658c95f865ee7677750dc85118077f 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 63 79 3.5E-5 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS04455 de32ee8fcf71eee548038866592dcc4b 77 Pfam PF03777 Small secreted domain (DUF320) 21 76 6.1E-30 T 10-11-2016 IPR005528 Domain of unknown function DUF320, Streptomyces species A4G23_RS15975 6af488d909221e6b4a66b690572d637c 141 Pfam PF09350 Domain of unknown function (DUF1992) 14 79 5.6E-20 T 10-11-2016 IPR018961 DnaJ homologue, subfamily C, member 28, conserved domain A4G23_RS05515 4fe6ae209eaf1434c8900aa204982c2d 96 Pfam PF14019 Protein of unknown function (DUF4235) 14 90 8.9E-27 T 10-11-2016 IPR025329 Protein of unknown function DUF4235 A4G23_RS14485 350d45ae0802eb6713b2cdac59f97963 179 Pfam PF10936 Protein of unknown function DUF2617 3 163 1.4E-61 T 10-11-2016 IPR024486 Protein of unknown function DUF2617 A4G23_RS14485 350d45ae0802eb6713b2cdac59f97963 179 ProDom PD339375 PRECURSOR SIGNAL SCO3656 SCO2458 CGL2705 MB2629 RV2598/MT2673.1 4 166 6.0E-68 T 10-11-2016 IPR024486 Protein of unknown function DUF2617 A4G23_RS25855 0e7d8887c9f7e841978d90e3060ac499 162 Gene3D G3DSA:3.40.50.1000 7 142 1.4E-16 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS25855 0e7d8887c9f7e841978d90e3060ac499 162 SUPERFAMILY SSF56784 4 142 3.16E-19 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS09390 f0b000dd2b9feb344c10ecfcf3c1db30 155 Pfam PF00578 AhpC/TSA family 8 134 1.8E-35 T 10-11-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A4G23_RS09390 f0b000dd2b9feb344c10ecfcf3c1db30 155 SUPERFAMILY SSF52833 4 153 1.07E-46 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS09390 f0b000dd2b9feb344c10ecfcf3c1db30 155 Gene3D G3DSA:3.40.30.10 2 153 2.0E-48 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS18525 0d524749dc9b5a654a821f75dc07fc11 251 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 73 246 4.7E-42 T 10-11-2016 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG A4G23_RS18525 0d524749dc9b5a654a821f75dc07fc11 251 SUPERFAMILY SSF102405 43 244 2.29E-62 T 10-11-2016 A4G23_RS18525 0d524749dc9b5a654a821f75dc07fc11 251 Gene3D G3DSA:3.40.50.450 52 247 7.9E-63 T 10-11-2016 A4G23_RS18525 0d524749dc9b5a654a821f75dc07fc11 251 Pfam PF03641 Possible lysine decarboxylase 115 243 6.1E-33 T 10-11-2016 IPR031100 LOG family A4G23_RS04615 4fc58437b534161761fe1dc3a0ff64c9 115 Pfam PF13471 Transglutaminase-like superfamily 3 99 1.2E-11 T 10-11-2016 IPR032708 Microcin J25-processing protein McjB, C-terminal A4G23_RS23025 9faa7acf1c5db02e73278f0d2216048f 355 Pfam PF03969 AFG1-like ATPase 250 346 3.2E-14 T 10-11-2016 IPR005654 ATPase, AFG1-like GO:0005524 A4G23_RS23025 9faa7acf1c5db02e73278f0d2216048f 355 Pfam PF03969 AFG1-like ATPase 50 235 3.0E-40 T 10-11-2016 IPR005654 ATPase, AFG1-like GO:0005524 A4G23_RS23025 9faa7acf1c5db02e73278f0d2216048f 355 SUPERFAMILY SSF52540 88 197 1.4E-7 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS23025 9faa7acf1c5db02e73278f0d2216048f 355 Gene3D G3DSA:3.40.50.300 24 214 4.1E-24 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS15090 faf5947bb838aadd286c1557edeb9295 370 Pfam PF13439 Glycosyltransferase Family 4 12 171 3.1E-25 T 10-11-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A4G23_RS15090 faf5947bb838aadd286c1557edeb9295 370 SUPERFAMILY SSF53756 1 362 1.74E-68 T 10-11-2016 A4G23_RS15090 faf5947bb838aadd286c1557edeb9295 370 Pfam PF00534 Glycosyl transferases group 1 181 291 1.2E-21 T 10-11-2016 IPR001296 Glycosyl transferase, family 1 A4G23_RS15090 faf5947bb838aadd286c1557edeb9295 370 Gene3D G3DSA:3.40.50.2000 152 337 1.8E-28 T 10-11-2016 A4G23_RS24850 2f1bea13ab1f1f98f13c812f3fbf7363 313 SUPERFAMILY SSF161111 24 220 6.93E-54 T 10-11-2016 A4G23_RS24850 2f1bea13ab1f1f98f13c812f3fbf7363 313 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 27 303 3.0E-92 T 10-11-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A4G23_RS24850 2f1bea13ab1f1f98f13c812f3fbf7363 313 SUPERFAMILY SSF160240 222 301 4.32E-11 T 10-11-2016 A4G23_RS24850 2f1bea13ab1f1f98f13c812f3fbf7363 313 Gene3D G3DSA:1.20.1510.10 25 219 2.0E-58 T 10-11-2016 IPR027469 Cation efflux protein transmembrane domain A4G23_RS24850 2f1bea13ab1f1f98f13c812f3fbf7363 313 Pfam PF01545 Cation efflux family 28 219 2.8E-47 T 10-11-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A4G23_RS24610 e4c3fc1fe5a2b3bddb6dcad9a2948329 292 Gene3D G3DSA:3.40.50.1820 2 289 2.4E-64 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS24610 e4c3fc1fe5a2b3bddb6dcad9a2948329 292 SUPERFAMILY SSF53474 2 289 2.2E-57 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS24610 e4c3fc1fe5a2b3bddb6dcad9a2948329 292 Pfam PF12697 Alpha/beta hydrolase family 23 278 3.0E-14 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS06620 984c308e900d7d2ebd64a38de3b469e8 359 Pfam PF07730 Histidine kinase 199 264 1.4E-18 T 10-11-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4G23_RS06620 984c308e900d7d2ebd64a38de3b469e8 359 SUPERFAMILY SSF55874 282 354 1.05E-6 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS27295 e9e2651f2be71d7b7583f8343ae6d84e 392 SUPERFAMILY SSF81606 190 383 1.57E-13 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS27295 e9e2651f2be71d7b7583f8343ae6d84e 392 SMART SM00331 176 382 1.3E-15 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS27295 e9e2651f2be71d7b7583f8343ae6d84e 392 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 202 382 1.3E-33 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS27295 e9e2651f2be71d7b7583f8343ae6d84e 392 Gene3D G3DSA:3.60.40.10 302 382 1.3E-6 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS00960 acbb14651b816d243da5b0f080486474 232 SMART SM00986 40 218 5.1E-29 T 10-11-2016 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4G23_RS00960 acbb14651b816d243da5b0f080486474 232 Pfam PF03167 Uracil DNA glycosylase superfamily 40 218 1.5E-26 T 10-11-2016 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4G23_RS00960 acbb14651b816d243da5b0f080486474 232 SUPERFAMILY SSF52141 8 222 7.52E-42 T 10-11-2016 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4G23_RS00960 acbb14651b816d243da5b0f080486474 232 Gene3D G3DSA:3.40.470.10 1 226 2.2E-52 T 10-11-2016 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4G23_RS00960 acbb14651b816d243da5b0f080486474 232 SMART SM00987 40 218 5.1E-29 T 10-11-2016 A4G23_RS05890 e6f87d3d17b962b79112a583a669d20a 307 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 291 1.4E-40 T 10-11-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 A4G23_RS12040 1946df4ccc8c4ad9a2f8340fc95d61e3 312 Pfam PF00480 ROK family 5 300 5.3E-59 T 10-11-2016 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A4G23_RS12040 1946df4ccc8c4ad9a2f8340fc95d61e3 312 Gene3D G3DSA:3.30.420.40 2 142 2.8E-33 T 10-11-2016 A4G23_RS12040 1946df4ccc8c4ad9a2f8340fc95d61e3 312 SUPERFAMILY SSF53067 4 304 6.67E-55 T 10-11-2016 A4G23_RS12040 1946df4ccc8c4ad9a2f8340fc95d61e3 312 Gene3D G3DSA:3.30.420.40 143 286 5.7E-49 T 10-11-2016 A4G23_RS24660 d50bae26716f4f75b9ddddff71d204a7 276 PIRSF PIRSF017393 1 276 1.3E-97 T 10-11-2016 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type A4G23_RS24660 d50bae26716f4f75b9ddddff71d204a7 276 SUPERFAMILY SSF53335 23 262 1.82E-47 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS24660 d50bae26716f4f75b9ddddff71d204a7 276 Pfam PF04672 S-adenosyl methyltransferase 14 276 2.0E-109 T 10-11-2016 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type A4G23_RS24660 d50bae26716f4f75b9ddddff71d204a7 276 Gene3D G3DSA:3.40.50.150 13 276 1.4E-111 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS06225 507bf3613a8529a26c087907ac7c7e7a 260 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 21 242 1.1E-44 T 10-11-2016 IPR003730 Multi-copper polyphenol oxidoreductase, laccase A4G23_RS06225 507bf3613a8529a26c087907ac7c7e7a 260 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 16 241 1.0E-66 T 10-11-2016 IPR003730 Multi-copper polyphenol oxidoreductase, laccase A4G23_RS06225 507bf3613a8529a26c087907ac7c7e7a 260 Gene3D G3DSA:3.60.140.10 7 243 2.8E-81 T 10-11-2016 IPR003730 Multi-copper polyphenol oxidoreductase, laccase A4G23_RS06225 507bf3613a8529a26c087907ac7c7e7a 260 SUPERFAMILY SSF64438 9 243 2.44E-71 T 10-11-2016 IPR011324 Cytotoxic necrotizing factor-like, catalytic A4G23_RS20100 9b06f558cc2a722fa882784de3403e31 385 SUPERFAMILY SSF50952 48 367 1.96E-47 T 10-11-2016 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 A4G23_RS20100 9b06f558cc2a722fa882784de3403e31 385 Gene3D G3DSA:2.120.10.30 59 382 3.6E-88 T 10-11-2016 IPR011042 Six-bladed beta-propeller, TolB-like A4G23_RS20100 9b06f558cc2a722fa882784de3403e31 385 Pfam PF07995 Glucose / Sorbosone dehydrogenase 69 368 3.9E-69 T 10-11-2016 IPR012938 Glucose/Sorbosone dehydrogenase GO:0005975|GO:0016901|GO:0048038 A4G23_RS22990 d3f8290c17da03a6d98afb908f2a8cd8 224 Gene3D G3DSA:3.60.160.10 25 218 4.1E-39 T 10-11-2016 IPR002838 Mitochondrial biogenesis protein AIM24 A4G23_RS22990 d3f8290c17da03a6d98afb908f2a8cd8 224 Pfam PF01987 Mitochondrial biogenesis AIM24 33 214 1.4E-31 T 10-11-2016 IPR002838 Mitochondrial biogenesis protein AIM24 A4G23_RS22990 d3f8290c17da03a6d98afb908f2a8cd8 224 SUPERFAMILY SSF51219 32 217 3.14E-44 T 10-11-2016 IPR016031 Tryptophan RNA-binding attenuator protein-like domain A4G23_RS14850 9db71daa8a8f6dbcd685a9bacbcdd828 221 Gene3D G3DSA:3.90.79.10 35 203 3.5E-34 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS14850 9db71daa8a8f6dbcd685a9bacbcdd828 221 SUPERFAMILY SSF55811 38 200 2.03E-23 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS14850 9db71daa8a8f6dbcd685a9bacbcdd828 221 Pfam PF00293 NUDIX domain 41 120 5.3E-9 T 10-11-2016 IPR000086 NUDIX hydrolase domain GO:0016787 A4G23_RS21355 6955c015706c4ec005bdf9f5d00f5801 246 Gene3D G3DSA:3.30.70.900 140 233 1.2E-16 T 10-11-2016 A4G23_RS21355 6955c015706c4ec005bdf9f5d00f5801 246 Gene3D G3DSA:3.30.70.900 10 83 2.3E-9 T 10-11-2016 A4G23_RS21355 6955c015706c4ec005bdf9f5d00f5801 246 Pfam PF03992 Antibiotic biosynthesis monooxygenase 141 210 2.1E-6 T 10-11-2016 IPR007138 Antibiotic biosynthesis monooxygenase domain A4G23_RS21355 6955c015706c4ec005bdf9f5d00f5801 246 SUPERFAMILY SSF54909 9 92 8.29E-5 T 10-11-2016 IPR011008 Dimeric alpha-beta barrel A4G23_RS21355 6955c015706c4ec005bdf9f5d00f5801 246 SUPERFAMILY SSF54909 135 224 2.62E-10 T 10-11-2016 IPR011008 Dimeric alpha-beta barrel A4G23_RS09440 8d0fa7aa3c40addee02f523e52ccb20b 249 Gene3D G3DSA:3.60.15.10 1 248 9.9E-56 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS09440 8d0fa7aa3c40addee02f523e52ccb20b 249 Pfam PF12706 Beta-lactamase superfamily domain 30 217 4.9E-20 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS09440 8d0fa7aa3c40addee02f523e52ccb20b 249 SMART SM00849 18 198 0.0011 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS09440 8d0fa7aa3c40addee02f523e52ccb20b 249 SUPERFAMILY SSF56281 1 249 1.97E-50 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS04935 da2f64556f49bb66ee52c6e71c3eb031 332 Pfam PF13579 Glycosyl transferase 4-like domain 1 122 1.1E-15 T 10-11-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A4G23_RS04935 da2f64556f49bb66ee52c6e71c3eb031 332 SUPERFAMILY SSF53756 13 321 7.33E-49 T 10-11-2016 A4G23_RS04935 da2f64556f49bb66ee52c6e71c3eb031 332 Pfam PF13692 Glycosyl transferases group 1 150 286 1.6E-16 T 10-11-2016 A4G23_RS04935 da2f64556f49bb66ee52c6e71c3eb031 332 Gene3D G3DSA:3.40.50.2000 139 298 9.0E-16 T 10-11-2016 A4G23_RS16805 37ee84e1b9e4ac992b874751fd699a87 432 SUPERFAMILY SSF53474 364 430 1.54E-9 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS16805 37ee84e1b9e4ac992b874751fd699a87 432 Pfam PF06441 Epoxide hydrolase N terminus 9 114 1.2E-36 T 10-11-2016 IPR010497 Epoxide hydrolase, N-terminal KEGG: 00980+3.3.2.9|Reactome: R-HSA-211945 A4G23_RS16805 37ee84e1b9e4ac992b874751fd699a87 432 SUPERFAMILY SSF53474 5 315 2.97E-83 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS16805 37ee84e1b9e4ac992b874751fd699a87 432 Gene3D G3DSA:3.40.50.1820 363 431 2.6E-135 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS16805 37ee84e1b9e4ac992b874751fd699a87 432 Gene3D G3DSA:3.40.50.1820 5 319 2.6E-135 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS16805 37ee84e1b9e4ac992b874751fd699a87 432 PRINTS PR00412 Epoxide hydrolase signature 105 123 5.2E-13 T 10-11-2016 IPR000639 Epoxide hydrolase-like GO:0003824 A4G23_RS16805 37ee84e1b9e4ac992b874751fd699a87 432 PRINTS PR00412 Epoxide hydrolase signature 134 149 5.2E-13 T 10-11-2016 IPR000639 Epoxide hydrolase-like GO:0003824 A4G23_RS16805 37ee84e1b9e4ac992b874751fd699a87 432 PRINTS PR00412 Epoxide hydrolase signature 405 427 5.2E-13 T 10-11-2016 IPR000639 Epoxide hydrolase-like GO:0003824 A4G23_RS16805 37ee84e1b9e4ac992b874751fd699a87 432 PRINTS PR00412 Epoxide hydrolase signature 179 192 5.2E-13 T 10-11-2016 IPR000639 Epoxide hydrolase-like GO:0003824 A4G23_RS16805 37ee84e1b9e4ac992b874751fd699a87 432 PRINTS PR00412 Epoxide hydrolase signature 193 206 5.2E-13 T 10-11-2016 IPR000639 Epoxide hydrolase-like GO:0003824 A4G23_RS15660 8ff79af49726410dcddc336d5b026570 135 Pfam PF13581 Histidine kinase-like ATPase domain 14 115 3.4E-8 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS15660 8ff79af49726410dcddc336d5b026570 135 SUPERFAMILY SSF55874 35 126 9.83E-7 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS15745 d5d788c5f0812c46229c7cd955880689 256 Pfam PF14016 Protein of unknown function (DUF4232) 119 247 8.1E-16 T 10-11-2016 IPR025326 Protein of unknown function DUF4232 A4G23_RS07105 5d0e0181affb6f22c0caf3e7418d82fe 260 Pfam PF03883 Protein of unknown function (DUF328) 2 239 3.0E-38 T 10-11-2016 IPR005583 Peroxide stress protein YaaA A4G23_RS07105 5d0e0181affb6f22c0caf3e7418d82fe 260 Hamap MF_00652 UPF0246 protein YaaA [yaaA]. 1 257 20.837 T 10-11-2016 IPR005583 Peroxide stress protein YaaA A4G23_RS00220 194a0a5088c788272ee2cf101dfd7abc 111 Pfam PF02694 Uncharacterised BCR, YnfA/UPF0060 family 5 110 4.0E-42 T 10-11-2016 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 A4G23_RS00220 194a0a5088c788272ee2cf101dfd7abc 111 SUPERFAMILY SSF103481 10 109 9.15E-10 T 10-11-2016 A4G23_RS00220 194a0a5088c788272ee2cf101dfd7abc 111 Hamap MF_00010 UPF0060 membrane protein YnfA [ynfA]. 4 109 20.196 T 10-11-2016 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 A4G23_RS23640 2055d49c4fd0a33a6952e793b5ecf720 110 SUPERFAMILY SSF57716 78 107 1.01E-6 T 10-11-2016 A4G23_RS23640 2055d49c4fd0a33a6952e793b5ecf720 110 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 76 107 5.0E-11 T 10-11-2016 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 A4G23_RS26365 cdf6842a7deaa75b491bba6d948939a5 131 SUPERFAMILY SSF54593 9 125 1.93E-12 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS26365 cdf6842a7deaa75b491bba6d948939a5 131 Gene3D G3DSA:3.10.180.10 4 125 5.4E-14 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS04515 9b5311ac5ea355e9aec025384586bfdb 551 Gene3D G3DSA:3.50.50.60 484 548 1.2E-60 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS04515 9b5311ac5ea355e9aec025384586bfdb 551 Gene3D G3DSA:3.50.50.60 3 274 1.2E-60 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS04515 9b5311ac5ea355e9aec025384586bfdb 551 SUPERFAMILY SSF51905 3 279 1.73E-31 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS04515 9b5311ac5ea355e9aec025384586bfdb 551 SUPERFAMILY SSF51905 487 549 1.73E-31 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS04515 9b5311ac5ea355e9aec025384586bfdb 551 Pfam PF00890 FAD binding domain 6 532 2.2E-107 T 10-11-2016 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4G23_RS04515 9b5311ac5ea355e9aec025384586bfdb 551 PIRSF PIRSF036654 1 550 3.7E-291 T 10-11-2016 IPR014614 Uncharacterised conserved protein UCP036654 GO:0016627|GO:0055114 A4G23_RS09945 5bca6d654279b20b4124c85a8a05bdb9 379 Gene3D G3DSA:3.40.50.10490 225 374 1.8E-8 T 10-11-2016 A4G23_RS09945 5bca6d654279b20b4124c85a8a05bdb9 379 SUPERFAMILY SSF53697 98 375 2.45E-44 T 10-11-2016 A4G23_RS09945 5bca6d654279b20b4124c85a8a05bdb9 379 Pfam PF10432 Bacterial phospho-glucose isomerase C-terminal SIS domain 226 375 7.2E-22 T 10-11-2016 IPR019490 Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase, C-terminal GO:0004347|GO:0004476|GO:0005975 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00051+5.3.1.8|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.8+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 A4G23_RS09945 5bca6d654279b20b4124c85a8a05bdb9 379 Gene3D G3DSA:3.40.50.10490 50 164 4.0E-4 T 10-11-2016 A4G23_RS05190 e6b2e83a3178057f91c1ac4d3487b071 127 Pfam PF04341 Protein of unknown function, DUF485 28 114 6.0E-31 T 10-11-2016 IPR007436 Protein of unknown function DUF485 A4G23_RS08745 08d53d862a5984a0e88c96aa09ed84a5 78 Pfam PF00403 Heavy-metal-associated domain 13 72 2.3E-16 T 10-11-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A4G23_RS08745 08d53d862a5984a0e88c96aa09ed84a5 78 PRINTS PR00944 Copper ion binding protein signature 22 35 8.4E-6 T 10-11-2016 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 A4G23_RS08745 08d53d862a5984a0e88c96aa09ed84a5 78 PRINTS PR00944 Copper ion binding protein signature 48 60 8.4E-6 T 10-11-2016 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 A4G23_RS08745 08d53d862a5984a0e88c96aa09ed84a5 78 PRINTS PR00944 Copper ion binding protein signature 10 22 8.4E-6 T 10-11-2016 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 A4G23_RS08745 08d53d862a5984a0e88c96aa09ed84a5 78 PRINTS PR00944 Copper ion binding protein signature 60 73 8.4E-6 T 10-11-2016 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 A4G23_RS08745 08d53d862a5984a0e88c96aa09ed84a5 78 Gene3D G3DSA:3.30.70.100 10 73 1.9E-21 T 10-11-2016 A4G23_RS08745 08d53d862a5984a0e88c96aa09ed84a5 78 SUPERFAMILY SSF55008 7 73 2.88E-17 T 10-11-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A4G23_RS19775 3d0015598d25d8b046ecf6dd28be6904 476 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 2 469 3.1E-165 T 10-11-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4G23_RS19775 3d0015598d25d8b046ecf6dd28be6904 476 Pfam PF00224 Pyruvate kinase, barrel domain 1 337 5.7E-127 T 10-11-2016 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4G23_RS19775 3d0015598d25d8b046ecf6dd28be6904 476 Gene3D G3DSA:3.40.1380.20 323 469 4.3E-42 T 10-11-2016 IPR015794 Pyruvate kinase, alpha/beta GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4G23_RS19775 3d0015598d25d8b046ecf6dd28be6904 476 Gene3D G3DSA:3.20.20.60 2 72 4.9E-104 T 10-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A4G23_RS19775 3d0015598d25d8b046ecf6dd28be6904 476 Gene3D G3DSA:3.20.20.60 167 322 4.9E-104 T 10-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A4G23_RS19775 3d0015598d25d8b046ecf6dd28be6904 476 Pfam PF02887 Pyruvate kinase, alpha/beta domain 356 468 5.2E-28 T 10-11-2016 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4G23_RS19775 3d0015598d25d8b046ecf6dd28be6904 476 Gene3D G3DSA:2.40.33.10 73 166 4.3E-30 T 10-11-2016 IPR015806 Pyruvate kinase, beta-barrel insert domain GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4G23_RS19775 3d0015598d25d8b046ecf6dd28be6904 476 PRINTS PR01050 Pyruvate kinase family signature 241 265 1.7E-62 T 10-11-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4G23_RS19775 3d0015598d25d8b046ecf6dd28be6904 476 PRINTS PR01050 Pyruvate kinase family signature 59 75 1.7E-62 T 10-11-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4G23_RS19775 3d0015598d25d8b046ecf6dd28be6904 476 PRINTS PR01050 Pyruvate kinase family signature 214 240 1.7E-62 T 10-11-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4G23_RS19775 3d0015598d25d8b046ecf6dd28be6904 476 PRINTS PR01050 Pyruvate kinase family signature 291 309 1.7E-62 T 10-11-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4G23_RS19775 3d0015598d25d8b046ecf6dd28be6904 476 PRINTS PR01050 Pyruvate kinase family signature 266 290 1.7E-62 T 10-11-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4G23_RS19775 3d0015598d25d8b046ecf6dd28be6904 476 PRINTS PR01050 Pyruvate kinase family signature 184 198 1.7E-62 T 10-11-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4G23_RS19775 3d0015598d25d8b046ecf6dd28be6904 476 PRINTS PR01050 Pyruvate kinase family signature 310 326 1.7E-62 T 10-11-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4G23_RS19775 3d0015598d25d8b046ecf6dd28be6904 476 SUPERFAMILY SSF50800 71 164 5.06E-26 T 10-11-2016 IPR011037 Pyruvate kinase-like, insert domain A4G23_RS19775 3d0015598d25d8b046ecf6dd28be6904 476 ProSitePatterns PS00110 Pyruvate kinase active site signature. 212 224 - T 10-11-2016 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4G23_RS19775 3d0015598d25d8b046ecf6dd28be6904 476 SUPERFAMILY SSF52935 320 470 8.9E-38 T 10-11-2016 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4G23_RS19775 3d0015598d25d8b046ecf6dd28be6904 476 SUPERFAMILY SSF51621 1 74 3.28E-97 T 10-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A4G23_RS19775 3d0015598d25d8b046ecf6dd28be6904 476 SUPERFAMILY SSF51621 154 337 3.28E-97 T 10-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A4G23_RS09400 b2329f4f7939c5c917047cfc9e9f1511 283 Pfam PF13392 HNH endonuclease 239 262 3.9E-6 T 10-11-2016 IPR003615 HNH nuclease A4G23_RS09400 b2329f4f7939c5c917047cfc9e9f1511 283 SMART SM00507 221 265 0.002 T 10-11-2016 IPR003615 HNH nuclease A4G23_RS26760 faa3c22c450ad22a15ee0f1b9ba122c3 351 Pfam PF13546 DDE superfamily endonuclease 2 204 3.9E-38 T 10-11-2016 A4G23_RS26030 9f0f1a3a87af492db401bde4b1cb7e47 536 SUPERFAMILY SSF51905 1 326 7.69E-38 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS26030 9f0f1a3a87af492db401bde4b1cb7e47 536 SUPERFAMILY SSF51905 473 505 7.69E-38 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS26030 9f0f1a3a87af492db401bde4b1cb7e47 536 Pfam PF01593 Flavin containing amine oxidoreductase 13 504 2.4E-11 T 10-11-2016 IPR002937 Amine oxidase GO:0016491|GO:0055114 A4G23_RS26030 9f0f1a3a87af492db401bde4b1cb7e47 536 Gene3D G3DSA:3.50.50.60 2 53 2.2E-28 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS26030 9f0f1a3a87af492db401bde4b1cb7e47 536 Gene3D G3DSA:3.50.50.60 457 516 2.2E-28 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS26030 9f0f1a3a87af492db401bde4b1cb7e47 536 Gene3D G3DSA:3.50.50.60 220 290 2.2E-28 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS05895 b132af8bac8e2840b30ee9ae3033d1a6 385 SUPERFAMILY SSF53822 31 375 2.83E-84 T 10-11-2016 IPR028082 Periplasmic binding protein-like I A4G23_RS05895 b132af8bac8e2840b30ee9ae3033d1a6 385 Pfam PF13458 Periplasmic binding protein 32 373 2.0E-59 T 10-11-2016 IPR028081 Leucine-binding protein domain A4G23_RS05895 b132af8bac8e2840b30ee9ae3033d1a6 385 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 262 280 4.9E-5 T 10-11-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 A4G23_RS05895 b132af8bac8e2840b30ee9ae3033d1a6 385 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 55 71 4.9E-5 T 10-11-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 A4G23_RS05895 b132af8bac8e2840b30ee9ae3033d1a6 385 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 33 49 4.9E-5 T 10-11-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 A4G23_RS05895 b132af8bac8e2840b30ee9ae3033d1a6 385 Gene3D G3DSA:3.40.50.2300 31 231 2.6E-54 T 10-11-2016 A4G23_RS10970 c61cfb20e0b8787e6a62e460f26a207e 409 Pfam PF14027 Protein of unknown function (DUF4243) 43 384 1.9E-33 T 10-11-2016 IPR025337 Domain of unknown function DUF4243 A4G23_RS16640 d25b10e6a93fdec536f1bfe19ad98187 139 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 38.018 T 10-11-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS16640 d25b10e6a93fdec536f1bfe19ad98187 139 SUPERFAMILY SSF54686 1 135 1.31E-55 T 10-11-2016 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 A4G23_RS16640 d25b10e6a93fdec536f1bfe19ad98187 139 PRINTS PR00060 Ribosomal protein L16 signature 88 117 1.4E-38 T 10-11-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS16640 d25b10e6a93fdec536f1bfe19ad98187 139 PRINTS PR00060 Ribosomal protein L16 signature 58 87 1.4E-38 T 10-11-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS16640 d25b10e6a93fdec536f1bfe19ad98187 139 PRINTS PR00060 Ribosomal protein L16 signature 24 36 1.4E-38 T 10-11-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS16640 d25b10e6a93fdec536f1bfe19ad98187 139 PRINTS PR00060 Ribosomal protein L16 signature 42 53 1.4E-38 T 10-11-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS16640 d25b10e6a93fdec536f1bfe19ad98187 139 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 1.4E-54 T 10-11-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS16640 d25b10e6a93fdec536f1bfe19ad98187 139 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 5.7E-48 T 10-11-2016 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 A4G23_RS16640 d25b10e6a93fdec536f1bfe19ad98187 139 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 10-11-2016 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS16640 d25b10e6a93fdec536f1bfe19ad98187 139 Gene3D G3DSA:3.90.1170.10 23 136 8.0E-53 T 10-11-2016 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 A4G23_RS16640 d25b10e6a93fdec536f1bfe19ad98187 139 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 10-11-2016 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS10145 10044ac385324d85749e8c42b52a4f15 396 Gene3D G3DSA:3.40.50.2000 200 371 1.4E-10 T 10-11-2016 A4G23_RS10145 10044ac385324d85749e8c42b52a4f15 396 Pfam PF13579 Glycosyl transferase 4-like domain 11 196 3.3E-19 T 10-11-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A4G23_RS10145 10044ac385324d85749e8c42b52a4f15 396 SUPERFAMILY SSF53756 2 395 2.96E-44 T 10-11-2016 A4G23_RS10145 10044ac385324d85749e8c42b52a4f15 396 Pfam PF13692 Glycosyl transferases group 1 221 360 2.3E-14 T 10-11-2016 A4G23_RS14040 1838e54e764fcd5cf15da63ae1dd2038 178 Pfam PF16571 FBP C-terminal treble-clef zinc-finger 8 172 1.9E-58 T 10-11-2016 IPR032330 Elongation factor G-binding protein, C-terminal treble-clef zinc-finger A4G23_RS00920 01af7144316d9417f6a6669bd7bd559c 201 Pfam PF01381 Helix-turn-helix 16 70 4.8E-16 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS00920 01af7144316d9417f6a6669bd7bd559c 201 SUPERFAMILY SSF51182 23 179 1.63E-14 T 10-11-2016 IPR011051 RmlC-like cupin domain A4G23_RS00920 01af7144316d9417f6a6669bd7bd559c 201 Gene3D G3DSA:1.10.260.40 13 81 1.5E-19 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS00920 01af7144316d9417f6a6669bd7bd559c 201 Gene3D G3DSA:2.60.120.10 88 175 4.4E-14 T 10-11-2016 IPR014710 RmlC-like jelly roll fold A4G23_RS00920 01af7144316d9417f6a6669bd7bd559c 201 Pfam PF07883 Cupin domain 117 172 1.4E-8 T 10-11-2016 IPR013096 Cupin 2, conserved barrel A4G23_RS00920 01af7144316d9417f6a6669bd7bd559c 201 SUPERFAMILY SSF47413 11 74 6.19E-17 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS00920 01af7144316d9417f6a6669bd7bd559c 201 SMART SM00530 15 70 9.6E-18 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS17305 4eec27197a4d72bb53037089725f6a81 393 SUPERFAMILY SSF56059 278 391 1.06E-71 T 10-11-2016 A4G23_RS17305 4eec27197a4d72bb53037089725f6a81 393 SUPERFAMILY SSF56059 1 169 1.06E-71 T 10-11-2016 A4G23_RS17305 4eec27197a4d72bb53037089725f6a81 393 SUPERFAMILY SSF52440 176 291 4.03E-34 T 10-11-2016 IPR016185 Pre-ATP-grasp domain A4G23_RS17305 4eec27197a4d72bb53037089725f6a81 393 Pfam PF03738 Glutathionylspermidine synthase preATP-grasp 12 392 6.1E-138 T 10-11-2016 IPR005494 Glutathionylspermidine synthase, pre-ATP-grasp-like domain A4G23_RS01965 4a9656d6f385f5d197fcc2783c221235 252 Pfam PF00106 short chain dehydrogenase 14 183 1.5E-20 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS01965 4a9656d6f385f5d197fcc2783c221235 252 SUPERFAMILY SSF51735 10 248 1.28E-34 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS01965 4a9656d6f385f5d197fcc2783c221235 252 Gene3D G3DSA:3.40.50.720 11 249 4.1E-35 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS20630 37dd5917dfb9e5b24795e27869c0596d 118 Gene3D G3DSA:3.40.1260.10 3 118 1.7E-30 T 10-11-2016 IPR027396 DsrEFH-like A4G23_RS20630 37dd5917dfb9e5b24795e27869c0596d 118 Pfam PF02635 DsrE/DsrF-like family 5 118 6.8E-21 T 10-11-2016 IPR003787 Sulphur relay, DsrE/F-like protein A4G23_RS20630 37dd5917dfb9e5b24795e27869c0596d 118 SUPERFAMILY SSF75169 4 118 1.16E-24 T 10-11-2016 IPR027396 DsrEFH-like A4G23_RS02940 f55d9e7524755215b0a3ec23842b64e6 417 Gene3D G3DSA:1.20.1250.20 23 191 7.2E-13 T 10-11-2016 A4G23_RS02940 f55d9e7524755215b0a3ec23842b64e6 417 Gene3D G3DSA:1.20.1250.20 215 392 1.1E-7 T 10-11-2016 A4G23_RS02940 f55d9e7524755215b0a3ec23842b64e6 417 SUPERFAMILY SSF103473 22 401 6.93E-30 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS02940 f55d9e7524755215b0a3ec23842b64e6 417 Pfam PF07690 Major Facilitator Superfamily 24 365 1.2E-22 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS24890 63604c2bec497882fde84864ddcd4697 316 SUPERFAMILY SSF48576 13 311 1.06E-57 T 10-11-2016 IPR008949 Isoprenoid synthase domain A4G23_RS24890 63604c2bec497882fde84864ddcd4697 316 TIGRFAM TIGR03464 HpnC: squalene synthase HpnC 12 305 3.0E-95 T 10-11-2016 IPR017827 Squalene synthase HpnC A4G23_RS24890 63604c2bec497882fde84864ddcd4697 316 Pfam PF00494 Squalene/phytoene synthase 13 295 2.0E-67 T 10-11-2016 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 A4G23_RS24890 63604c2bec497882fde84864ddcd4697 316 Gene3D G3DSA:1.10.600.10 17 306 2.5E-51 T 10-11-2016 IPR008949 Isoprenoid synthase domain A4G23_RS24835 43ea0bb72438c38a1b22a390fc323a59 147 SUPERFAMILY SSF55874 40 147 4.11E-12 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS24835 43ea0bb72438c38a1b22a390fc323a59 147 Gene3D G3DSA:3.30.565.10 26 146 2.2E-8 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS24835 43ea0bb72438c38a1b22a390fc323a59 147 Pfam PF13581 Histidine kinase-like ATPase domain 26 122 8.0E-13 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS11270 8376b304444ac236561776fd3d3d83f3 330 Pfam PF02195 ParB-like nuclease domain 8 92 2.6E-7 T 10-11-2016 IPR003115 ParB/Sulfiredoxin A4G23_RS11270 8376b304444ac236561776fd3d3d83f3 330 SUPERFAMILY SSF110849 5 84 7.67E-9 T 10-11-2016 IPR003115 ParB/Sulfiredoxin A4G23_RS11270 8376b304444ac236561776fd3d3d83f3 330 Gene3D G3DSA:3.90.1530.10 29 94 6.0E-5 T 10-11-2016 A4G23_RS11270 8376b304444ac236561776fd3d3d83f3 330 SMART SM00470 8 92 1.8E-7 T 10-11-2016 IPR003115 ParB/Sulfiredoxin A4G23_RS02550 d557ddd854d24102ee26f5e9e3f9236b 205 SUPERFAMILY SSF52096 19 202 9.95E-51 T 10-11-2016 IPR029045 ClpP/crotonase-like domain A4G23_RS02550 d557ddd854d24102ee26f5e9e3f9236b 205 Pfam PF00574 Clp protease 22 202 3.4E-60 T 10-11-2016 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA A4G23_RS02550 d557ddd854d24102ee26f5e9e3f9236b 205 Gene3D G3DSA:3.90.226.10 12 201 1.2E-60 T 10-11-2016 IPR029045 ClpP/crotonase-like domain A4G23_RS02550 d557ddd854d24102ee26f5e9e3f9236b 205 PRINTS PR00127 Clp protease catalytic subunit P signature 67 87 2.0E-34 T 10-11-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4G23_RS02550 d557ddd854d24102ee26f5e9e3f9236b 205 PRINTS PR00127 Clp protease catalytic subunit P signature 178 197 2.0E-34 T 10-11-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4G23_RS02550 d557ddd854d24102ee26f5e9e3f9236b 205 PRINTS PR00127 Clp protease catalytic subunit P signature 27 42 2.0E-34 T 10-11-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4G23_RS02550 d557ddd854d24102ee26f5e9e3f9236b 205 PRINTS PR00127 Clp protease catalytic subunit P signature 119 138 2.0E-34 T 10-11-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4G23_RS02550 d557ddd854d24102ee26f5e9e3f9236b 205 PRINTS PR00127 Clp protease catalytic subunit P signature 98 115 2.0E-34 T 10-11-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4G23_RS02550 d557ddd854d24102ee26f5e9e3f9236b 205 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 11 203 34.345 T 10-11-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4G23_RS13435 10822a311963c50df4d679373408d2f8 188 Pfam PF12089 Transmembrane domain of unknown function (DUF3566) 68 186 5.6E-42 T 10-11-2016 IPR021949 Domain of unknown function DUF3566. transmembrane A4G23_RS07405 6b10ea9cd85a713f9abe27a0a6815e72 191 Pfam PF02342 TerD domain 3 187 2.0E-86 T 10-11-2016 IPR003325 TerD domain GO:0006950 A4G23_RS07405 6b10ea9cd85a713f9abe27a0a6815e72 191 Gene3D G3DSA:2.60.60.30 18 185 1.1E-76 T 10-11-2016 A4G23_RS22490 d98a8cf0b037e997643e3ff1dc7091f1 89 Gene3D G3DSA:1.10.10.10 2 48 1.1E-16 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS22490 d98a8cf0b037e997643e3ff1dc7091f1 89 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 23 35 2.6E-6 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS22490 d98a8cf0b037e997643e3ff1dc7091f1 89 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 7 23 2.6E-6 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS22490 d98a8cf0b037e997643e3ff1dc7091f1 89 ProSitePatterns PS00622 LuxR-type HTH domain signature. 7 34 - T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS22490 d98a8cf0b037e997643e3ff1dc7091f1 89 SUPERFAMILY SSF46894 2 48 6.8E-14 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS22490 d98a8cf0b037e997643e3ff1dc7091f1 89 SMART SM00421 1 47 1.5E-8 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS22490 d98a8cf0b037e997643e3ff1dc7091f1 89 Pfam PF00196 Bacterial regulatory proteins, luxR family 2 45 8.3E-14 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS17690 b3a7db0f4dabfbf192ec4378d8abc8f0 303 Pfam PF00171 Aldehyde dehydrogenase family 28 259 3.5E-40 T 10-11-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A4G23_RS17690 b3a7db0f4dabfbf192ec4378d8abc8f0 303 Gene3D G3DSA:3.40.605.10 7 259 4.8E-54 T 10-11-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A4G23_RS17690 b3a7db0f4dabfbf192ec4378d8abc8f0 303 SUPERFAMILY SSF53720 10 260 3.8E-45 T 10-11-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A4G23_RS18240 c3425ad990de38ed5fd9a4697caeae26 467 Pfam PF00206 Lyase 17 342 1.8E-102 T 10-11-2016 IPR022761 Fumarate lyase, N-terminal A4G23_RS18240 c3425ad990de38ed5fd9a4697caeae26 467 ProSitePatterns PS00163 Fumarate lyases signature. 317 326 - T 10-11-2016 IPR020557 Fumarate lyase, conserved site GO:0003824 A4G23_RS18240 c3425ad990de38ed5fd9a4697caeae26 467 PRINTS PR00145 Argininosuccinate lyase family signature 317 333 4.8E-5 T 10-11-2016 A4G23_RS18240 c3425ad990de38ed5fd9a4697caeae26 467 PRINTS PR00145 Argininosuccinate lyase family signature 175 195 4.8E-5 T 10-11-2016 A4G23_RS18240 c3425ad990de38ed5fd9a4697caeae26 467 Gene3D G3DSA:1.10.275.10 9 138 3.2E-53 T 10-11-2016 IPR024083 Fumarase/histidase, N-terminal A4G23_RS18240 c3425ad990de38ed5fd9a4697caeae26 467 Gene3D G3DSA:1.10.40.30 408 467 2.5E-22 T 10-11-2016 A4G23_RS18240 c3425ad990de38ed5fd9a4697caeae26 467 PRINTS PR00149 Fumarate lyase superfamily signature 317 333 9.4E-34 T 10-11-2016 IPR000362 Fumarate lyase family A4G23_RS18240 c3425ad990de38ed5fd9a4697caeae26 467 PRINTS PR00149 Fumarate lyase superfamily signature 271 298 9.4E-34 T 10-11-2016 IPR000362 Fumarate lyase family A4G23_RS18240 c3425ad990de38ed5fd9a4697caeae26 467 PRINTS PR00149 Fumarate lyase superfamily signature 134 152 9.4E-34 T 10-11-2016 IPR000362 Fumarate lyase family A4G23_RS18240 c3425ad990de38ed5fd9a4697caeae26 467 PRINTS PR00149 Fumarate lyase superfamily signature 180 198 9.4E-34 T 10-11-2016 IPR000362 Fumarate lyase family A4G23_RS18240 c3425ad990de38ed5fd9a4697caeae26 467 Pfam PF10415 Fumarase C C-terminus 408 466 7.2E-21 T 10-11-2016 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A4G23_RS18240 c3425ad990de38ed5fd9a4697caeae26 467 Gene3D G3DSA:1.20.200.10 139 403 4.4E-97 T 10-11-2016 A4G23_RS18240 c3425ad990de38ed5fd9a4697caeae26 467 Hamap MF_00743 Fumarate hydratase class II [fumC]. 9 467 82.035 T 10-11-2016 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A4G23_RS18240 c3425ad990de38ed5fd9a4697caeae26 467 SUPERFAMILY SSF48557 9 466 5.34E-146 T 10-11-2016 IPR008948 L-Aspartase-like GO:0003824 A4G23_RS00345 0170217d17309c80af02ed181f99b2a3 500 Gene3D G3DSA:1.20.1250.20 25 222 8.9E-26 T 10-11-2016 A4G23_RS00345 0170217d17309c80af02ed181f99b2a3 500 Pfam PF00083 Sugar (and other) transporter 59 477 1.0E-40 T 10-11-2016 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 A4G23_RS00345 0170217d17309c80af02ed181f99b2a3 500 Gene3D G3DSA:1.20.1250.20 280 474 4.6E-14 T 10-11-2016 A4G23_RS00345 0170217d17309c80af02ed181f99b2a3 500 SUPERFAMILY SSF103473 15 476 3.66E-67 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS02100 0693a080ecab004c72b41bbd28a50c14 339 SUPERFAMILY SSF53850 32 327 1.51E-62 T 10-11-2016 A4G23_RS02100 0693a080ecab004c72b41bbd28a50c14 339 Pfam PF13343 Bacterial extracellular solute-binding protein 83 311 2.4E-27 T 10-11-2016 A4G23_RS02100 0693a080ecab004c72b41bbd28a50c14 339 Gene3D G3DSA:3.40.190.10 138 285 5.0E-48 T 10-11-2016 A4G23_RS02100 0693a080ecab004c72b41bbd28a50c14 339 Gene3D G3DSA:3.40.190.10 32 137 3.0E-10 T 10-11-2016 A4G23_RS02100 0693a080ecab004c72b41bbd28a50c14 339 PIRSF PIRSF002825 3 339 4.9E-92 T 10-11-2016 IPR026045 Ferric binding protein A4G23_RS23680 7c877040390805726438791e4c42d7b3 250 Gene3D G3DSA:1.20.950.20 15 227 3.0E-75 T 10-11-2016 A4G23_RS23680 7c877040390805726438791e4c42d7b3 250 TIGRFAM TIGR00351 narI: respiratory nitrate reductase, gamma subunit 15 235 9.2E-59 T 10-11-2016 IPR003816 Nitrate reductase, gamma subunit GO:0008940|GO:0009325|GO:0055114 KEGG: 00910+1.7.99.4 A4G23_RS23680 7c877040390805726438791e4c42d7b3 250 SUPERFAMILY SSF103501 14 235 1.96E-65 T 10-11-2016 IPR023234 NarG-like domain A4G23_RS23680 7c877040390805726438791e4c42d7b3 250 Pfam PF02665 Nitrate reductase gamma subunit 16 235 3.9E-82 T 10-11-2016 IPR023234 NarG-like domain A4G23_RS17500 d0496c776f98e61f484ef2554dfad863 142 SUPERFAMILY SSF54427 8 130 4.91E-10 T 10-11-2016 IPR032710 NTF2-like domain A4G23_RS17500 d0496c776f98e61f484ef2554dfad863 142 Gene3D G3DSA:3.10.450.50 15 132 9.7E-4 T 10-11-2016 IPR032710 NTF2-like domain A4G23_RS03160 3189fe1ae379b2a9a378168fb3f9f280 142 SUPERFAMILY SSF103196 10 135 4.01E-35 T 10-11-2016 A4G23_RS03160 3189fe1ae379b2a9a378168fb3f9f280 142 Gene3D G3DSA:3.30.450.30 11 132 8.0E-27 T 10-11-2016 A4G23_RS03160 3189fe1ae379b2a9a378168fb3f9f280 142 Pfam PF03259 Roadblock/LC7 domain 15 106 8.3E-26 T 10-11-2016 IPR004942 Roadblock/LAMTOR2 domain A4G23_RS03160 3189fe1ae379b2a9a378168fb3f9f280 142 SMART SM00960 16 106 8.1E-29 T 10-11-2016 IPR004942 Roadblock/LAMTOR2 domain A4G23_RS09700 e1154c77fbcf2b2f3a3c86c2bb56a6e8 388 SUPERFAMILY SSF103473 10 381 1.31E-20 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS09700 e1154c77fbcf2b2f3a3c86c2bb56a6e8 388 Gene3D G3DSA:1.20.1250.20 9 183 8.0E-7 T 10-11-2016 A4G23_RS09700 e1154c77fbcf2b2f3a3c86c2bb56a6e8 388 Gene3D G3DSA:1.20.1250.20 216 377 2.3E-5 T 10-11-2016 A4G23_RS02160 f0ca1bde1114ae846ce9bab49e4e2db7 276 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 258 5.9E-20 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS02160 f0ca1bde1114ae846ce9bab49e4e2db7 276 Gene3D G3DSA:1.10.3720.10 4 263 5.8E-64 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS02160 f0ca1bde1114ae846ce9bab49e4e2db7 276 SUPERFAMILY SSF161098 4 276 1.09E-72 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS16940 89179cac57ed5f80495e3582026776bf 257 PIRSF PIRSF000126 1 253 2.8E-65 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS16940 89179cac57ed5f80495e3582026776bf 257 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2 179 0.0046 T 10-11-2016 A4G23_RS16940 89179cac57ed5f80495e3582026776bf 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 2.2E-27 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS16940 89179cac57ed5f80495e3582026776bf 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 2.2E-27 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS16940 89179cac57ed5f80495e3582026776bf 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 2.2E-27 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS16940 89179cac57ed5f80495e3582026776bf 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 2.2E-27 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS16940 89179cac57ed5f80495e3582026776bf 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 2.2E-27 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS16940 89179cac57ed5f80495e3582026776bf 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 1.5E-11 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS16940 89179cac57ed5f80495e3582026776bf 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 1.5E-11 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS16940 89179cac57ed5f80495e3582026776bf 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 1.5E-11 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS16940 89179cac57ed5f80495e3582026776bf 257 Pfam PF00106 short chain dehydrogenase 4 188 1.6E-43 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS16940 89179cac57ed5f80495e3582026776bf 257 Gene3D G3DSA:3.40.50.720 4 213 2.3E-56 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS16940 89179cac57ed5f80495e3582026776bf 257 SUPERFAMILY SSF51735 4 221 2.59E-55 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS17635 f5e23164fee1d55514cf9e3d22deab59 257 SUPERFAMILY SSF53474 32 218 4.69E-20 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS17635 f5e23164fee1d55514cf9e3d22deab59 257 Pfam PF01738 Dienelactone hydrolase family 80 209 1.4E-4 T 10-11-2016 IPR002925 Dienelactone hydrolase GO:0016787 A4G23_RS17635 f5e23164fee1d55514cf9e3d22deab59 257 Gene3D G3DSA:3.40.50.1820 56 217 6.2E-17 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS09100 bae23a851e5871b2be4d78b9450b5b51 534 Pfam PF14440 Xanthomonas XOO_2897-like deaminase 405 492 1.0E-17 T 10-11-2016 IPR032722 Deaminase, Xanthomonas XOO_2897-like A4G23_RS03435 c2747d24cb88f249b51ae6e51e973d68 355 Pfam PF14606 GDSL-like Lipase/Acylhydrolase family 170 345 1.0E-23 T 10-11-2016 IPR013830 SGNH hydrolase-type esterase domain A4G23_RS03435 c2747d24cb88f249b51ae6e51e973d68 355 Gene3D G3DSA:3.40.50.1110 170 349 7.8E-19 T 10-11-2016 IPR013830 SGNH hydrolase-type esterase domain A4G23_RS03435 c2747d24cb88f249b51ae6e51e973d68 355 SUPERFAMILY SSF52266 165 349 9.01E-27 T 10-11-2016 IPR013830 SGNH hydrolase-type esterase domain A4G23_RS10305 e6f673d10c5f77d0bec02d1d38cc659f 322 SUPERFAMILY SSF52266 61 260 8.86E-31 T 10-11-2016 IPR013830 SGNH hydrolase-type esterase domain A4G23_RS10305 e6f673d10c5f77d0bec02d1d38cc659f 322 Gene3D G3DSA:3.40.50.1110 62 256 9.0E-26 T 10-11-2016 IPR013830 SGNH hydrolase-type esterase domain A4G23_RS10305 e6f673d10c5f77d0bec02d1d38cc659f 322 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 67 245 2.7E-24 T 10-11-2016 IPR013830 SGNH hydrolase-type esterase domain A4G23_RS13205 130284efd5b1e5efb484a4caaece78f0 183 Pfam PF10759 Protein of unknown function (DUF2587) 33 181 8.4E-80 T 10-11-2016 IPR019695 Bacterial proteasome activator GO:0061136 A4G23_RS17845 7542c5f04572b112cc70c85954c294ca 70 Pfam PF13822 Acyl-CoA carboxylase epsilon subunit 2 63 2.7E-16 T 10-11-2016 IPR032716 Acyl-CoA carboxylase epsilon subunit A4G23_RS05765 d3d31a7ff84293f838895ea08d50b240 303 SUPERFAMILY SSF110581 7 302 6.15E-98 T 10-11-2016 A4G23_RS05765 d3d31a7ff84293f838895ea08d50b240 303 Hamap MF_01876 Pseudouridine-5'-phosphate glycosidase [psuG]. 11 303 38.016 T 10-11-2016 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 A4G23_RS05765 d3d31a7ff84293f838895ea08d50b240 303 Pfam PF04227 Indigoidine synthase A like protein 12 300 1.3E-110 T 10-11-2016 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 A4G23_RS12870 aaf3427c11888d5e1b3db4324e701b95 83 Pfam PF11273 Protein of unknown function (DUF3073) 2 62 2.9E-21 T 10-11-2016 IPR021426 Protein of unknown function DUF3073 A4G23_RS10040 c95588d2505060a037af96e4c0be67f8 177 Pfam PF03061 Thioesterase superfamily 32 102 4.1E-20 T 10-11-2016 IPR006683 Thioesterase domain Reactome: R-HSA-75105 A4G23_RS10040 c95588d2505060a037af96e4c0be67f8 177 SUPERFAMILY SSF54637 11 166 1.37E-45 T 10-11-2016 IPR029069 HotDog domain A4G23_RS10040 c95588d2505060a037af96e4c0be67f8 177 Gene3D G3DSA:3.10.129.10 11 165 2.4E-55 T 10-11-2016 IPR029069 HotDog domain A4G23_RS13870 3bfb7792e1492e7ac576bc9d605f421b 181 SUPERFAMILY SSF88946 22 110 1.41E-13 T 10-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS13870 3bfb7792e1492e7ac576bc9d605f421b 181 Gene3D G3DSA:1.10.10.10 113 173 4.4E-21 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS13870 3bfb7792e1492e7ac576bc9d605f421b 181 SUPERFAMILY SSF88659 111 173 2.62E-16 T 10-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS13870 3bfb7792e1492e7ac576bc9d605f421b 181 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 20 176 3.0E-63 T 10-11-2016 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 A4G23_RS13870 3bfb7792e1492e7ac576bc9d605f421b 181 Pfam PF08281 Sigma-70, region 4 119 171 3.0E-17 T 10-11-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS13870 3bfb7792e1492e7ac576bc9d605f421b 181 Pfam PF04542 Sigma-70 region 2 27 91 1.7E-9 T 10-11-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS13870 3bfb7792e1492e7ac576bc9d605f421b 181 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 30 173 5.0E-22 T 10-11-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4G23_RS13870 3bfb7792e1492e7ac576bc9d605f421b 181 Gene3D G3DSA:1.10.1740.10 20 92 9.3E-14 T 10-11-2016 A4G23_RS26995 d671dada9e645610eaa9c1a402f9a707 323 TIGRFAM TIGR03557 F420_G6P_family: F420-dependent oxidoreductase, G6PDH family 3 317 6.2E-141 T 10-11-2016 IPR019945 F420-dependent glucose-6-phosphate dehydrogenase-related A4G23_RS26995 d671dada9e645610eaa9c1a402f9a707 323 Gene3D G3DSA:3.20.20.30 1 308 1.4E-69 T 10-11-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4G23_RS26995 d671dada9e645610eaa9c1a402f9a707 323 SUPERFAMILY SSF51679 1 308 1.57E-67 T 10-11-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4G23_RS26995 d671dada9e645610eaa9c1a402f9a707 323 Pfam PF00296 Luciferase-like monooxygenase 7 289 6.4E-52 T 10-11-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4G23_RS15665 d21f34e0617ec1c7eb7b6e007d8eeb8f 221 Pfam PF08241 Methyltransferase domain 53 148 1.1E-10 T 10-11-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 A4G23_RS15665 d21f34e0617ec1c7eb7b6e007d8eeb8f 221 Gene3D G3DSA:3.40.50.150 44 199 7.2E-22 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS15665 d21f34e0617ec1c7eb7b6e007d8eeb8f 221 SUPERFAMILY SSF53335 46 206 3.47E-28 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS18925 9ca95922c70e44eef7df6e5b5dd11652 213 Gene3D G3DSA:3.40.50.1820 25 200 9.7E-16 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS18925 9ca95922c70e44eef7df6e5b5dd11652 213 SUPERFAMILY SSF53474 2 208 1.8E-16 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS15540 98e68cc197cefed9d154c112f3f4bd22 321 Pfam PF12833 Helix-turn-helix domain 230 308 2.5E-20 T 10-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4G23_RS15540 98e68cc197cefed9d154c112f3f4bd22 321 SUPERFAMILY SSF46689 209 258 1.7E-9 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS15540 98e68cc197cefed9d154c112f3f4bd22 321 Gene3D G3DSA:1.10.10.60 211 261 3.4E-16 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS15540 98e68cc197cefed9d154c112f3f4bd22 321 SMART SM00342 224 307 2.3E-24 T 10-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4G23_RS15540 98e68cc197cefed9d154c112f3f4bd22 321 SUPERFAMILY SSF46689 261 311 8.06E-8 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS15540 98e68cc197cefed9d154c112f3f4bd22 321 SUPERFAMILY SSF52317 1 188 5.5E-44 T 10-11-2016 IPR029062 Class I glutamine amidotransferase-like A4G23_RS15540 98e68cc197cefed9d154c112f3f4bd22 321 Gene3D G3DSA:1.10.10.60 262 311 3.9E-9 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS15540 98e68cc197cefed9d154c112f3f4bd22 321 Pfam PF01965 DJ-1/PfpI family 48 167 1.8E-15 T 10-11-2016 IPR002818 DJ-1/PfpI A4G23_RS15540 98e68cc197cefed9d154c112f3f4bd22 321 Gene3D G3DSA:3.40.50.880 1 210 6.4E-45 T 10-11-2016 IPR029062 Class I glutamine amidotransferase-like A4G23_RS08735 9c9813b39611c97bec526b3b7a47ebcd 65 Pfam PF13411 MerR HTH family regulatory protein 9 47 1.2E-4 T 10-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4G23_RS08735 9c9813b39611c97bec526b3b7a47ebcd 65 SUPERFAMILY SSF46955 7 56 2.43E-7 T 10-11-2016 IPR009061 Putative DNA-binding domain A4G23_RS08735 9c9813b39611c97bec526b3b7a47ebcd 65 Gene3D G3DSA:1.10.1660.10 8 48 2.5E-5 T 10-11-2016 A4G23_RS09190 5226f152514c488e6fbc6347bd28ce0d 464 SUPERFAMILY SSF48452 348 385 9.87E-6 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS09190 5226f152514c488e6fbc6347bd28ce0d 464 SUPERFAMILY SSF48452 217 299 9.87E-6 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS09190 5226f152514c488e6fbc6347bd28ce0d 464 Gene3D G3DSA:1.25.40.10 207 295 1.9E-5 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS23975 3a74bc742aac43c4930ced54ed8d87e8 318 SUPERFAMILY SSF51197 8 303 2.2E-54 T 10-11-2016 A4G23_RS23975 3a74bc742aac43c4930ced54ed8d87e8 318 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 18 249 4.2E-35 T 10-11-2016 IPR008775 Phytanoyl-CoA dioxygenase A4G23_RS23975 3a74bc742aac43c4930ced54ed8d87e8 318 TIGRFAM TIGR01762 chlorin-enz: chlorinating enzyme 8 302 4.5E-128 T 10-11-2016 IPR010092 Chlorinating enzyme A4G23_RS23975 3a74bc742aac43c4930ced54ed8d87e8 318 Gene3D G3DSA:2.60.120.620 3 270 7.0E-54 T 10-11-2016 A4G23_RS09030 ca84dce8bd28b3fa22fec36885c70cb5 434 SUPERFAMILY SSF53474 172 413 8.84E-24 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS09030 ca84dce8bd28b3fa22fec36885c70cb5 434 SUPERFAMILY SSF53474 109 126 8.84E-24 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS09030 ca84dce8bd28b3fa22fec36885c70cb5 434 Pfam PF03403 Platelet-activating factor acetylhydrolase, isoform II 80 216 2.2E-8 T 10-11-2016 IPR005065 Platelet-activating factor acetylhydrolase GO:0003847|GO:0016042 KEGG: 00565+3.1.1.47 A4G23_RS09030 ca84dce8bd28b3fa22fec36885c70cb5 434 Pfam PF03403 Platelet-activating factor acetylhydrolase, isoform II 272 408 4.5E-5 T 10-11-2016 IPR005065 Platelet-activating factor acetylhydrolase GO:0003847|GO:0016042 KEGG: 00565+3.1.1.47 A4G23_RS09030 ca84dce8bd28b3fa22fec36885c70cb5 434 Gene3D G3DSA:3.40.50.1820 83 128 1.7E-50 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS09030 ca84dce8bd28b3fa22fec36885c70cb5 434 Gene3D G3DSA:3.40.50.1820 174 430 1.7E-50 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS06365 026b1a723db302b645d86ceabd804ec5 74 Pfam PF02597 ThiS family 11 74 6.2E-16 T 10-11-2016 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 A4G23_RS06365 026b1a723db302b645d86ceabd804ec5 74 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 11 74 2.5E-22 T 10-11-2016 IPR010035 ThiS, thiamine-biosynthesis A4G23_RS06365 026b1a723db302b645d86ceabd804ec5 74 SUPERFAMILY SSF54285 11 73 1.38E-16 T 10-11-2016 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp A4G23_RS06365 026b1a723db302b645d86ceabd804ec5 74 Gene3D G3DSA:3.10.20.30 10 74 9.2E-26 T 10-11-2016 IPR012675 Beta-grasp domain A4G23_RS11635 6eebe5e5bfd8205080f82ee84eb0aab1 302 Pfam PF00892 EamA-like transporter family 163 292 8.8E-18 T 10-11-2016 IPR000620 EamA domain GO:0016020|GO:0016021 A4G23_RS11635 6eebe5e5bfd8205080f82ee84eb0aab1 302 Pfam PF00892 EamA-like transporter family 17 144 1.4E-12 T 10-11-2016 IPR000620 EamA domain GO:0016020|GO:0016021 A4G23_RS11635 6eebe5e5bfd8205080f82ee84eb0aab1 302 SUPERFAMILY SSF103481 45 146 4.32E-13 T 10-11-2016 A4G23_RS11635 6eebe5e5bfd8205080f82ee84eb0aab1 302 SUPERFAMILY SSF103481 196 295 2.35E-14 T 10-11-2016 A4G23_RS17965 ce09cde0fdb97b2365c051b4f7ba2523 165 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 10 160 5.8E-45 T 10-11-2016 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 A4G23_RS17965 ce09cde0fdb97b2365c051b4f7ba2523 165 SUPERFAMILY SSF46557 8 82 6.93E-23 T 10-11-2016 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 A4G23_RS17965 ce09cde0fdb97b2365c051b4f7ba2523 165 Gene3D G3DSA:3.10.50.30 81 163 6.9E-17 T 10-11-2016 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 A4G23_RS17965 ce09cde0fdb97b2365c051b4f7ba2523 165 Pfam PF03449 Transcription elongation factor, N-terminal 10 79 8.0E-25 T 10-11-2016 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 A4G23_RS17965 ce09cde0fdb97b2365c051b4f7ba2523 165 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 86 161 4.0E-14 T 10-11-2016 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 A4G23_RS17965 ce09cde0fdb97b2365c051b4f7ba2523 165 Hamap MF_00105 Transcription elongation factor GreA [greA]. 7 161 28.518 T 10-11-2016 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 A4G23_RS17965 ce09cde0fdb97b2365c051b4f7ba2523 165 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 22 53 - T 10-11-2016 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 A4G23_RS17965 ce09cde0fdb97b2365c051b4f7ba2523 165 Gene3D G3DSA:1.10.287.180 8 79 5.4E-27 T 10-11-2016 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 A4G23_RS17965 ce09cde0fdb97b2365c051b4f7ba2523 165 SUPERFAMILY SSF54534 84 160 1.15E-11 T 10-11-2016 A4G23_RS17965 ce09cde0fdb97b2365c051b4f7ba2523 165 PIRSF PIRSF006092 3 164 9.2E-35 T 10-11-2016 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 A4G23_RS15210 7c10c6d3c4bb0325606dd67f87fbd141 294 SMART SM00530 25 80 3.5E-5 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS15210 7c10c6d3c4bb0325606dd67f87fbd141 294 Pfam PF13560 Helix-turn-helix domain 22 84 4.8E-14 T 10-11-2016 A4G23_RS15210 7c10c6d3c4bb0325606dd67f87fbd141 294 SUPERFAMILY SSF47413 19 76 5.07E-7 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS15210 7c10c6d3c4bb0325606dd67f87fbd141 294 Gene3D G3DSA:1.10.260.40 21 76 1.5E-6 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS08135 44ae0307394c9921cdb908c8f26724c3 106 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 103 22.358 T 10-11-2016 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS08135 44ae0307394c9921cdb908c8f26724c3 106 ProSitePatterns PS01169 Ribosomal protein L21 signature. 72 94 - T 10-11-2016 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS08135 44ae0307394c9921cdb908c8f26724c3 106 SUPERFAMILY SSF141091 1 101 1.09E-29 T 10-11-2016 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS08135 44ae0307394c9921cdb908c8f26724c3 106 Pfam PF00829 Ribosomal prokaryotic L21 protein 2 101 3.7E-31 T 10-11-2016 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS08135 44ae0307394c9921cdb908c8f26724c3 106 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 101 2.4E-26 T 10-11-2016 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS22835 b261ccb7827174252c66d59b3e42aba1 288 TIGRFAM TIGR02548 casB_cse2: CRISPR type I-E/ECOLI-associated protein CasB/Cse2 101 253 1.4E-18 T 10-11-2016 IPR013382 CRISPR-associated protein Cse2 A4G23_RS22835 b261ccb7827174252c66d59b3e42aba1 288 Pfam PF09485 CRISPR-associated protein Cse2 (CRISPR_cse2) 53 252 1.6E-25 T 10-11-2016 IPR013382 CRISPR-associated protein Cse2 A4G23_RS25470 2b8d3ac770ebd96bf4af96cc7d349a80 287 SUPERFAMILY SSF144091 10 63 2.62E-41 T 10-11-2016 A4G23_RS25470 2b8d3ac770ebd96bf4af96cc7d349a80 287 SUPERFAMILY SSF144091 93 255 2.62E-41 T 10-11-2016 A4G23_RS25470 2b8d3ac770ebd96bf4af96cc7d349a80 287 Pfam PF01694 Rhomboid family 102 251 6.5E-41 T 10-11-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 A4G23_RS25470 2b8d3ac770ebd96bf4af96cc7d349a80 287 Gene3D G3DSA:1.20.1540.10 13 250 5.1E-45 T 10-11-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 A4G23_RS11295 f307a39e452ef9e9ab95c2c19eccaa56 114 Pfam PF03551 Transcriptional regulator PadR-like family 14 86 4.3E-23 T 10-11-2016 IPR005149 Transcription regulator PadR, N-terminal A4G23_RS11295 f307a39e452ef9e9ab95c2c19eccaa56 114 Gene3D G3DSA:1.10.10.10 2 103 6.7E-30 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS11295 f307a39e452ef9e9ab95c2c19eccaa56 114 SUPERFAMILY SSF46785 3 104 6.34E-24 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS11455 1c835aadd7d8a1af74d0c8e97dd9e66c 422 Gene3D G3DSA:3.40.50.2300 308 374 1.2E-16 T 10-11-2016 A4G23_RS11455 1c835aadd7d8a1af74d0c8e97dd9e66c 422 Gene3D G3DSA:3.40.50.2300 43 161 1.2E-16 T 10-11-2016 A4G23_RS11455 1c835aadd7d8a1af74d0c8e97dd9e66c 422 Pfam PF13458 Periplasmic binding protein 56 374 1.6E-22 T 10-11-2016 IPR028081 Leucine-binding protein domain A4G23_RS11455 1c835aadd7d8a1af74d0c8e97dd9e66c 422 SUPERFAMILY SSF53822 60 377 1.04E-23 T 10-11-2016 IPR028082 Periplasmic binding protein-like I A4G23_RS24015 8bf82edd3d34e012181862b1fd4808ce 402 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 13 110 7.9E-7 T 10-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 A4G23_RS24015 8bf82edd3d34e012181862b1fd4808ce 402 Gene3D G3DSA:2.40.110.10 122 208 7.3E-27 T 10-11-2016 A4G23_RS24015 8bf82edd3d34e012181862b1fd4808ce 402 SUPERFAMILY SSF47203 249 393 1.66E-7 T 10-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4G23_RS24015 8bf82edd3d34e012181862b1fd4808ce 402 SUPERFAMILY SSF56645 13 215 1.57E-33 T 10-11-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 A4G23_RS24015 8bf82edd3d34e012181862b1fd4808ce 402 Gene3D G3DSA:1.10.540.10 5 119 3.3E-36 T 10-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 A4G23_RS24015 8bf82edd3d34e012181862b1fd4808ce 402 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 249 379 2.7E-23 T 10-11-2016 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain A4G23_RS24015 8bf82edd3d34e012181862b1fd4808ce 402 PIRSF PIRSF016578 1 401 2.0E-114 T 10-11-2016 A4G23_RS24015 8bf82edd3d34e012181862b1fd4808ce 402 Gene3D G3DSA:1.20.140.10 209 396 5.6E-35 T 10-11-2016 A4G23_RS06765 3fb845853626ab0e4878f13067eff061 156 Pfam PF06271 RDD family 42 148 4.4E-14 T 10-11-2016 IPR010432 RDD A4G23_RS06765 3fb845853626ab0e4878f13067eff061 156 PIRSF PIRSF021697 3 155 2.9E-53 T 10-11-2016 IPR016795 Uncharacterised conserved protein UCP021697, membrane A4G23_RS02015 11823c944e81dfbf65e8539a45ac5953 315 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 31 291 1.6E-16 T 10-11-2016 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 A4G23_RS02015 11823c944e81dfbf65e8539a45ac5953 315 Gene3D G3DSA:3.30.420.40 185 276 1.9E-6 T 10-11-2016 A4G23_RS02015 11823c944e81dfbf65e8539a45ac5953 315 SUPERFAMILY SSF53067 115 297 6.48E-38 T 10-11-2016 A4G23_RS21870 98bfa70d0618de3396492bf872cbf988 205 Pfam PF03029 Conserved hypothetical ATP binding protein 27 194 2.3E-24 T 10-11-2016 IPR004130 GPN-loop GTPase A4G23_RS21870 98bfa70d0618de3396492bf872cbf988 205 Gene3D G3DSA:3.40.50.300 22 196 1.5E-19 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS21870 98bfa70d0618de3396492bf872cbf988 205 SUPERFAMILY SSF52540 23 195 2.5E-26 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS26120 10e5eefcd8164a014001d4b99c4a0c94 316 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 133 154 - T 10-11-2016 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 A4G23_RS26120 10e5eefcd8164a014001d4b99c4a0c94 316 SUPERFAMILY SSF50129 1 133 7.3E-29 T 10-11-2016 IPR011032 GroES-like A4G23_RS26120 10e5eefcd8164a014001d4b99c4a0c94 316 SMART SM00829 11 315 1.0E-27 T 10-11-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A4G23_RS26120 10e5eefcd8164a014001d4b99c4a0c94 316 Gene3D G3DSA:3.90.180.10 1 138 5.0E-35 T 10-11-2016 IPR011032 GroES-like A4G23_RS26120 10e5eefcd8164a014001d4b99c4a0c94 316 SUPERFAMILY SSF51735 105 264 2.23E-46 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS26120 10e5eefcd8164a014001d4b99c4a0c94 316 Pfam PF00107 Zinc-binding dehydrogenase 144 267 2.6E-30 T 10-11-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A4G23_RS26120 10e5eefcd8164a014001d4b99c4a0c94 316 Gene3D G3DSA:3.40.50.720 139 254 2.7E-30 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS02140 ca66731cab034221c7e08adef0091969 318 Pfam PF11271 Protein of unknown function (DUF3068) 8 304 2.1E-66 T 10-11-2016 IPR021424 Protein of unknown function DUF3068 A4G23_RS10130 9a4656fc2febb92600a6f5e70f7acedb 353 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 99 255 2.8E-45 T 10-11-2016 IPR004474 Cell envelope-related transcriptional attenuator domain A4G23_RS10130 9a4656fc2febb92600a6f5e70f7acedb 353 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 98 255 3.9E-53 T 10-11-2016 IPR004474 Cell envelope-related transcriptional attenuator domain A4G23_RS22435 5cac239cffe271da92474fb6fc47cfdc 560 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 254 308 - T 10-11-2016 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS22435 5cac239cffe271da92474fb6fc47cfdc 560 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 25 529 1.3E-213 T 10-11-2016 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 A4G23_RS22435 5cac239cffe271da92474fb6fc47cfdc 560 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 34 477 2.6E-145 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS22435 5cac239cffe271da92474fb6fc47cfdc 560 Gene3D G3DSA:1.20.210.10 19 543 1.0E-193 T 10-11-2016 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS22435 5cac239cffe271da92474fb6fc47cfdc 560 PRINTS PR01165 Cytochrome c oxidase subunit I signature 71 94 1.2E-102 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS22435 5cac239cffe271da92474fb6fc47cfdc 560 PRINTS PR01165 Cytochrome c oxidase subunit I signature 24 49 1.2E-102 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS22435 5cac239cffe271da92474fb6fc47cfdc 560 PRINTS PR01165 Cytochrome c oxidase subunit I signature 433 454 1.2E-102 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS22435 5cac239cffe271da92474fb6fc47cfdc 560 PRINTS PR01165 Cytochrome c oxidase subunit I signature 320 341 1.2E-102 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS22435 5cac239cffe271da92474fb6fc47cfdc 560 PRINTS PR01165 Cytochrome c oxidase subunit I signature 383 402 1.2E-102 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS22435 5cac239cffe271da92474fb6fc47cfdc 560 PRINTS PR01165 Cytochrome c oxidase subunit I signature 202 221 1.2E-102 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS22435 5cac239cffe271da92474fb6fc47cfdc 560 PRINTS PR01165 Cytochrome c oxidase subunit I signature 231 252 1.2E-102 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS22435 5cac239cffe271da92474fb6fc47cfdc 560 PRINTS PR01165 Cytochrome c oxidase subunit I signature 141 153 1.2E-102 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS22435 5cac239cffe271da92474fb6fc47cfdc 560 PRINTS PR01165 Cytochrome c oxidase subunit I signature 98 122 1.2E-102 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS22435 5cac239cffe271da92474fb6fc47cfdc 560 PRINTS PR01165 Cytochrome c oxidase subunit I signature 355 373 1.2E-102 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS22435 5cac239cffe271da92474fb6fc47cfdc 560 PRINTS PR01165 Cytochrome c oxidase subunit I signature 252 273 1.2E-102 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS22435 5cac239cffe271da92474fb6fc47cfdc 560 PRINTS PR01165 Cytochrome c oxidase subunit I signature 298 313 1.2E-102 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS22435 5cac239cffe271da92474fb6fc47cfdc 560 PRINTS PR01165 Cytochrome c oxidase subunit I signature 173 191 1.2E-102 T 10-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS22435 5cac239cffe271da92474fb6fc47cfdc 560 SUPERFAMILY SSF81442 21 532 2.49E-176 T 10-11-2016 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS12420 5283c992b9e73580cb40fdca61b1c796 120 SUPERFAMILY SSF75169 3 114 6.39E-18 T 10-11-2016 IPR027396 DsrEFH-like A4G23_RS12420 5283c992b9e73580cb40fdca61b1c796 120 Gene3D G3DSA:3.40.1260.10 3 112 2.2E-16 T 10-11-2016 IPR027396 DsrEFH-like A4G23_RS12420 5283c992b9e73580cb40fdca61b1c796 120 Pfam PF02635 DsrE/DsrF-like family 3 114 9.8E-12 T 10-11-2016 IPR003787 Sulphur relay, DsrE/F-like protein A4G23_RS22555 2a88e04812004206ae73b8d6072588fe 215 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 102 187 7.1E-13 T 10-11-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 A4G23_RS22555 2a88e04812004206ae73b8d6072588fe 215 Gene3D G3DSA:3.90.470.20 102 211 8.0E-7 T 10-11-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 A4G23_RS22555 2a88e04812004206ae73b8d6072588fe 215 PRINTS PR01399 Enterobactin synthetase component D signature 37 57 3.4E-25 T 10-11-2016 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 A4G23_RS22555 2a88e04812004206ae73b8d6072588fe 215 PRINTS PR01399 Enterobactin synthetase component D signature 67 85 3.4E-25 T 10-11-2016 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 A4G23_RS22555 2a88e04812004206ae73b8d6072588fe 215 PRINTS PR01399 Enterobactin synthetase component D signature 144 160 3.4E-25 T 10-11-2016 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 A4G23_RS22555 2a88e04812004206ae73b8d6072588fe 215 SUPERFAMILY SSF56214 100 211 3.45E-16 T 10-11-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 A4G23_RS25550 99d93e0fc16bd66bad3bc17d8c1ede13 68 SUPERFAMILY SSF50118 1 65 2.88E-23 T 10-11-2016 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor A4G23_RS25550 99d93e0fc16bd66bad3bc17d8c1ede13 68 Pfam PF08940 Domain of unknown function (DUF1918) 1 58 2.0E-26 T 10-11-2016 IPR015035 Domain of unknown function DUF1918 A4G23_RS22405 78deea95ca2684f12733431d2208c557 637 TIGRFAM TIGR03604 TOMM_cyclo_SagD: thiazole/oxazole-forming peptide maturase, SagD family component 251 637 8.4E-91 T 10-11-2016 IPR027624 Thiazole/oxazole-forming peptide maturase, SagD family component A4G23_RS22405 78deea95ca2684f12733431d2208c557 637 TIGRFAM TIGR03882 cyclo_dehyd_2: bacteriocin biosynthesis cyclodehydratase domain 46 216 1.7E-30 T 10-11-2016 IPR022291 Bacteriocin biosynthesis, cyclodehydratase domain A4G23_RS22405 78deea95ca2684f12733431d2208c557 637 Pfam PF02624 YcaO cyclodehydratase, ATP-ad Mg2+-binding 251 592 5.0E-81 T 10-11-2016 IPR003776 YcaO-like domain A4G23_RS10570 1ab92ddfd8b486f2d610b329f0b04522 257 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 221 253 5.2E-5 T 10-11-2016 IPR019931 LPXTG cell wall anchor domain A4G23_RS16960 5e671cd532bc3faaca485869e5a8630e 203 Pfam PF00072 Response regulator receiver domain 4 115 1.1E-25 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS16960 5e671cd532bc3faaca485869e5a8630e 203 SMART SM00448 2 115 4.9E-26 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS16960 5e671cd532bc3faaca485869e5a8630e 203 Pfam PF00196 Bacterial regulatory proteins, luxR family 141 194 3.5E-18 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS16960 5e671cd532bc3faaca485869e5a8630e 203 Gene3D G3DSA:1.10.10.10 144 201 7.9E-23 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS16960 5e671cd532bc3faaca485869e5a8630e 203 SUPERFAMILY SSF46894 128 202 2.79E-20 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS16960 5e671cd532bc3faaca485869e5a8630e 203 SMART SM00421 139 196 1.2E-22 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS16960 5e671cd532bc3faaca485869e5a8630e 203 Gene3D G3DSA:3.40.50.2300 1 143 5.2E-34 T 10-11-2016 A4G23_RS16960 5e671cd532bc3faaca485869e5a8630e 203 SUPERFAMILY SSF52172 1 127 1.37E-29 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS16960 5e671cd532bc3faaca485869e5a8630e 203 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 142 156 3.2E-12 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS16960 5e671cd532bc3faaca485869e5a8630e 203 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 172 3.2E-12 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS16960 5e671cd532bc3faaca485869e5a8630e 203 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 184 3.2E-12 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS16960 5e671cd532bc3faaca485869e5a8630e 203 ProSitePatterns PS00622 LuxR-type HTH domain signature. 156 183 - T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS09870 6326c866a11a836ea466cfc4a43dee1f 383 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 30 363 7.7E-106 T 10-11-2016 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A4G23_RS09870 6326c866a11a836ea466cfc4a43dee1f 383 Pfam PF01008 Initiation factor 2 subunit family 63 364 1.0E-61 T 10-11-2016 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 A4G23_RS09870 6326c866a11a836ea466cfc4a43dee1f 383 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 16 374 35.101 T 10-11-2016 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A4G23_RS09870 6326c866a11a836ea466cfc4a43dee1f 383 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 48 364 1.5E-83 T 10-11-2016 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A4G23_RS09870 6326c866a11a836ea466cfc4a43dee1f 383 Gene3D G3DSA:3.40.50.10470 173 365 2.1E-61 T 10-11-2016 A4G23_RS09870 6326c866a11a836ea466cfc4a43dee1f 383 SUPERFAMILY SSF100950 27 364 1.51E-95 T 10-11-2016 A4G23_RS09870 6326c866a11a836ea466cfc4a43dee1f 383 Gene3D G3DSA:1.20.120.420 30 172 9.6E-36 T 10-11-2016 IPR027363 Methylthioribose-1-phosphate isomerase-like, N-terminal domain KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A4G23_RS25200 8ba34f1d515785b203065d691af8664a 87 Pfam PF09851 Short C-terminal domain 54 78 2.4E-8 T 10-11-2016 IPR018649 SHOCT domain A4G23_RS03955 1c8c27f9c6ccef1a234353a9c6c2daaa 394 Gene3D G3DSA:3.20.20.190 62 384 8.1E-92 T 10-11-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 A4G23_RS03955 1c8c27f9c6ccef1a234353a9c6c2daaa 394 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 67 383 8.7E-45 T 10-11-2016 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 A4G23_RS03955 1c8c27f9c6ccef1a234353a9c6c2daaa 394 SUPERFAMILY SSF51695 61 383 1.94E-80 T 10-11-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 A4G23_RS09895 504616fd9cc82a5fa73bd1b0927fb33f 436 Pfam PF01882 Protein of unknown function DUF58 192 277 2.8E-19 T 10-11-2016 IPR002881 Domain of unknown function DUF58 A4G23_RS14890 25626b9f23fae0aa2781abc07304f004 327 SUPERFAMILY SSF52540 99 245 2.85E-21 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS14890 25626b9f23fae0aa2781abc07304f004 327 SUPERFAMILY SSF52540 1 51 2.85E-21 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS14890 25626b9f23fae0aa2781abc07304f004 327 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 6 223 5.5E-11 T 10-11-2016 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A4G23_RS14890 25626b9f23fae0aa2781abc07304f004 327 Gene3D G3DSA:3.40.50.300 1 251 2.2E-28 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS09630 6f7741184447b2bc975f7c74c060e235 772 SUPERFAMILY SSF56003 151 767 2.49E-123 T 10-11-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 A4G23_RS09630 6f7741184447b2bc975f7c74c060e235 772 Gene3D G3DSA:3.30.365.10 371 474 2.1E-40 T 10-11-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 A4G23_RS09630 6f7741184447b2bc975f7c74c060e235 772 Gene3D G3DSA:3.30.365.10 642 767 2.1E-40 T 10-11-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 A4G23_RS09630 6f7741184447b2bc975f7c74c060e235 772 SMART SM01008 44 150 2.9E-43 T 10-11-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead A4G23_RS09630 6f7741184447b2bc975f7c74c060e235 772 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 45 149 1.8E-27 T 10-11-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead A4G23_RS09630 6f7741184447b2bc975f7c74c060e235 772 Gene3D G3DSA:3.30.365.10 482 641 3.2E-23 T 10-11-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 A4G23_RS09630 6f7741184447b2bc975f7c74c060e235 772 Gene3D G3DSA:3.30.365.10 294 368 9.2E-30 T 10-11-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 A4G23_RS09630 6f7741184447b2bc975f7c74c060e235 772 Gene3D G3DSA:3.30.365.10 139 198 9.2E-30 T 10-11-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 A4G23_RS09630 6f7741184447b2bc975f7c74c060e235 772 Gene3D G3DSA:3.30.365.10 201 291 1.7E-20 T 10-11-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 A4G23_RS09630 6f7741184447b2bc975f7c74c060e235 772 Gene3D G3DSA:3.90.1170.50 17 138 2.7E-41 T 10-11-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead A4G23_RS09630 6f7741184447b2bc975f7c74c060e235 772 SUPERFAMILY SSF54665 19 151 6.54E-39 T 10-11-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead A4G23_RS09630 6f7741184447b2bc975f7c74c060e235 772 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 172 713 6.7E-111 T 10-11-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 A4G23_RS21295 c7e357fb3ec454e9c7c1cd087201722c 964 Pfam PF08471 Class II vitamin B12-dependent ribonucleotide reductase 55 138 1.6E-19 T 10-11-2016 IPR013678 Ribonucleotide reductase class II vitamin B12-dependent, N-terminal domain GO:0004748|GO:0050897|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A4G23_RS21295 c7e357fb3ec454e9c7c1cd087201722c 964 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 94 708 1.1E-190 T 10-11-2016 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A4G23_RS21295 c7e357fb3ec454e9c7c1cd087201722c 964 Gene3D G3DSA:3.20.70.20 69 485 3.7E-101 T 10-11-2016 A4G23_RS21295 c7e357fb3ec454e9c7c1cd087201722c 964 Gene3D G3DSA:3.20.70.20 544 590 3.7E-101 T 10-11-2016 A4G23_RS21295 c7e357fb3ec454e9c7c1cd087201722c 964 Gene3D G3DSA:3.20.70.20 657 702 3.7E-101 T 10-11-2016 A4G23_RS21295 c7e357fb3ec454e9c7c1cd087201722c 964 PRINTS PR01183 Ribonucleotide reductase large chain signature 437 459 1.5E-16 T 10-11-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4G23_RS21295 c7e357fb3ec454e9c7c1cd087201722c 964 PRINTS PR01183 Ribonucleotide reductase large chain signature 234 253 1.5E-16 T 10-11-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4G23_RS21295 c7e357fb3ec454e9c7c1cd087201722c 964 PRINTS PR01183 Ribonucleotide reductase large chain signature 465 488 1.5E-16 T 10-11-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4G23_RS21295 c7e357fb3ec454e9c7c1cd087201722c 964 PRINTS PR01183 Ribonucleotide reductase large chain signature 361 372 1.5E-16 T 10-11-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4G23_RS21295 c7e357fb3ec454e9c7c1cd087201722c 964 PRINTS PR01183 Ribonucleotide reductase large chain signature 544 571 1.5E-16 T 10-11-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4G23_RS21295 c7e357fb3ec454e9c7c1cd087201722c 964 PRINTS PR01183 Ribonucleotide reductase large chain signature 399 422 1.5E-16 T 10-11-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4G23_RS21295 c7e357fb3ec454e9c7c1cd087201722c 964 SUPERFAMILY SSF51998 159 594 5.8E-133 T 10-11-2016 A4G23_RS21295 c7e357fb3ec454e9c7c1cd087201722c 964 SUPERFAMILY SSF51998 628 702 5.8E-133 T 10-11-2016 A4G23_RS21295 c7e357fb3ec454e9c7c1cd087201722c 964 Pfam PF02867 Ribonucleotide reductase, barrel domain 159 698 4.0E-149 T 10-11-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4G23_RS25945 aee5d360301f725af535ee2639c7d036 226 Pfam PF12277 Protein of unknown function (DUF3618) 3 47 1.0E-14 T 10-11-2016 IPR022062 Protein of unknown function DUF3618 A4G23_RS26400 443c418537dca2f573b603b6ba4b39d0 207 Pfam PF07883 Cupin domain 122 190 4.0E-15 T 10-11-2016 IPR013096 Cupin 2, conserved barrel A4G23_RS26400 443c418537dca2f573b603b6ba4b39d0 207 SUPERFAMILY SSF47413 17 80 3.38E-17 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS26400 443c418537dca2f573b603b6ba4b39d0 207 Gene3D G3DSA:2.60.120.10 70 193 7.4E-19 T 10-11-2016 IPR014710 RmlC-like jelly roll fold A4G23_RS26400 443c418537dca2f573b603b6ba4b39d0 207 Gene3D G3DSA:1.10.260.40 17 69 5.0E-19 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS26400 443c418537dca2f573b603b6ba4b39d0 207 SMART SM00530 21 76 5.7E-15 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS26400 443c418537dca2f573b603b6ba4b39d0 207 Pfam PF01381 Helix-turn-helix 22 75 2.7E-15 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS26400 443c418537dca2f573b603b6ba4b39d0 207 SUPERFAMILY SSF51182 69 197 4.21E-23 T 10-11-2016 IPR011051 RmlC-like cupin domain A4G23_RS01680 7a762b568c4a36e26f95fe9182faeac3 342 Pfam PF00756 Putative esterase 56 255 2.6E-19 T 10-11-2016 IPR000801 Putative esterase Reactome: R-HSA-156590 A4G23_RS01680 7a762b568c4a36e26f95fe9182faeac3 342 Gene3D G3DSA:3.40.50.1820 46 336 5.9E-53 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS01680 7a762b568c4a36e26f95fe9182faeac3 342 SUPERFAMILY SSF53474 49 334 5.97E-35 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS10235 3920ea0b4a47eb27651c728938121607 418 SUPERFAMILY SSF53187 18 231 9.71E-71 T 10-11-2016 A4G23_RS10235 3920ea0b4a47eb27651c728938121607 418 SUPERFAMILY SSF53187 342 416 9.71E-71 T 10-11-2016 A4G23_RS10235 3920ea0b4a47eb27651c728938121607 418 Gene3D G3DSA:3.40.630.10 19 234 5.3E-93 T 10-11-2016 A4G23_RS10235 3920ea0b4a47eb27651c728938121607 418 Gene3D G3DSA:3.40.630.10 358 416 5.3E-93 T 10-11-2016 A4G23_RS10235 3920ea0b4a47eb27651c728938121607 418 Pfam PF01546 Peptidase family M20/M25/M40 85 413 1.4E-25 T 10-11-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A4G23_RS10235 3920ea0b4a47eb27651c728938121607 418 PIRSF PIRSF001235 15 418 2.5E-121 T 10-11-2016 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 A4G23_RS10235 3920ea0b4a47eb27651c728938121607 418 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 22 411 1.1E-85 T 10-11-2016 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 A4G23_RS10235 3920ea0b4a47eb27651c728938121607 418 Gene3D G3DSA:3.30.70.360 235 335 1.7E-28 T 10-11-2016 IPR011650 Peptidase M20, dimerisation domain A4G23_RS10235 3920ea0b4a47eb27651c728938121607 418 SUPERFAMILY SSF55031 224 333 6.11E-19 T 10-11-2016 IPR011650 Peptidase M20, dimerisation domain A4G23_RS18845 3d331497e99d164d8d35d8405fc35cd3 153 Gene3D G3DSA:3.90.1170.40 17 151 1.0E-46 T 10-11-2016 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4G23_RS18845 3d331497e99d164d8d35d8405fc35cd3 153 Pfam PF02391 MoaE protein 22 133 3.2E-36 T 10-11-2016 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4G23_RS18845 3d331497e99d164d8d35d8405fc35cd3 153 SUPERFAMILY SSF54690 20 151 1.96E-40 T 10-11-2016 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4G23_RS12650 20ed8e5fa11298eed956c2f6b3cf5da8 200 SUPERFAMILY SSF55729 5 166 4.43E-18 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS12650 20ed8e5fa11298eed956c2f6b3cf5da8 200 Pfam PF00583 Acetyltransferase (GNAT) family 71 160 8.2E-11 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS12650 20ed8e5fa11298eed956c2f6b3cf5da8 200 Gene3D G3DSA:3.40.630.30 3 164 9.1E-21 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS19680 04abd8e3c1d3baa80e6ebc6c43c64660 146 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 122 6.0E-20 T 10-11-2016 A4G23_RS19680 04abd8e3c1d3baa80e6ebc6c43c64660 146 Gene3D G3DSA:3.10.180.10 1 136 5.9E-38 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS19680 04abd8e3c1d3baa80e6ebc6c43c64660 146 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 4 136 3.0E-44 T 10-11-2016 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|Reactome: R-HSA-71032 A4G23_RS19680 04abd8e3c1d3baa80e6ebc6c43c64660 146 SUPERFAMILY SSF54593 1 138 5.91E-34 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS18460 1cb22b64018c00ec8d96f9eb4b0d8d4d 453 ProSitePatterns PS00708 Prolyl endopeptidase family serine active site. 289 319 - T 10-11-2016 IPR002471 Peptidase S9, serine active site GO:0004252|GO:0006508 A4G23_RS18460 1cb22b64018c00ec8d96f9eb4b0d8d4d 453 Gene3D G3DSA:3.40.50.1820 204 450 3.3E-67 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS18460 1cb22b64018c00ec8d96f9eb4b0d8d4d 453 Gene3D G3DSA:2.140.10.30 2 184 2.2E-18 T 10-11-2016 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 A4G23_RS18460 1cb22b64018c00ec8d96f9eb4b0d8d4d 453 SUPERFAMILY SSF53474 202 451 5.54E-53 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS18460 1cb22b64018c00ec8d96f9eb4b0d8d4d 453 SUPERFAMILY SSF82171 12 183 1.71E-7 T 10-11-2016 A4G23_RS18460 1cb22b64018c00ec8d96f9eb4b0d8d4d 453 Pfam PF00326 Prolyl oligopeptidase family 249 451 1.5E-39 T 10-11-2016 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 A4G23_RS12740 d7f2c5f01536365a3c5f084a9a5e92cd 543 SUPERFAMILY SSF48452 301 516 4.55E-5 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS18120 3532ce120fadeab205715ed14e094b49 312 Pfam PF00482 Type II secretion system (T2SS), protein F 145 269 4.5E-17 T 10-11-2016 IPR018076 Type II secretion system F domain A4G23_RS08830 cd0873a4ead52fb7791685fa967cd1ae 484 Pfam PF05576 PS-10 peptidase S37 44 482 1.1E-227 T 10-11-2016 IPR008761 Peptidase S37, tripeptidyl aminopeptidase A4G23_RS08830 cd0873a4ead52fb7791685fa967cd1ae 484 SUPERFAMILY SSF53474 278 311 5.73E-16 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS08830 cd0873a4ead52fb7791685fa967cd1ae 484 SUPERFAMILY SSF53474 376 444 5.73E-16 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS08830 cd0873a4ead52fb7791685fa967cd1ae 484 SUPERFAMILY SSF53474 97 210 5.73E-16 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS08830 cd0873a4ead52fb7791685fa967cd1ae 484 Gene3D G3DSA:3.40.50.1820 326 327 4.4E-10 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS08830 cd0873a4ead52fb7791685fa967cd1ae 484 Gene3D G3DSA:3.40.50.1820 383 428 4.4E-10 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS08830 cd0873a4ead52fb7791685fa967cd1ae 484 Gene3D G3DSA:3.40.50.1820 75 259 4.4E-10 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS17655 b7cc1e3e42cf8acdc3755470c3278740 197 Pfam PF04892 VanZ like family 15 134 1.5E-16 T 10-11-2016 IPR006976 VanZ-like A4G23_RS26195 4ee6720b879c9b822d202c072b84fb59 74 Pfam PF17196 Protein of unknown function (DUF5133) 1 64 1.8E-26 T 10-11-2016 IPR033457 Protein of unknown function DUF5133 A4G23_RS17705 a5f12a46bf02b920642e747fe945f1b3 729 Gene3D G3DSA:3.40.50.300 195 304 8.3E-26 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS17705 a5f12a46bf02b920642e747fe945f1b3 729 Gene3D G3DSA:3.40.50.300 510 605 8.3E-26 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS17705 a5f12a46bf02b920642e747fe945f1b3 729 SUPERFAMILY SSF52540 194 274 2.67E-37 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS17705 a5f12a46bf02b920642e747fe945f1b3 729 SUPERFAMILY SSF52540 500 728 2.67E-37 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS17705 a5f12a46bf02b920642e747fe945f1b3 729 Gene3D G3DSA:3.40.50.300 666 728 5.8E-8 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS17705 a5f12a46bf02b920642e747fe945f1b3 729 Pfam PF13245 Part of AAA domain 208 277 5.0E-12 T 10-11-2016 A4G23_RS25245 f67d2e737275bbba433e901b84c8acbf 126 Pfam PF04343 Protein of unknown function, DUF488 10 123 2.0E-31 T 10-11-2016 IPR007438 Protein of unknown function DUF488 A4G23_RS21700 f4b8808e43c2bc541e3b27ce719e2b69 295 SUPERFAMILY SSF53098 120 290 1.52E-36 T 10-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 A4G23_RS21700 f4b8808e43c2bc541e3b27ce719e2b69 295 Pfam PF13276 HTH-like domain 46 103 8.3E-18 T 10-11-2016 IPR025948 HTH-like domain A4G23_RS21700 f4b8808e43c2bc541e3b27ce719e2b69 295 Gene3D G3DSA:3.30.420.10 122 281 7.4E-36 T 10-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 A4G23_RS21700 f4b8808e43c2bc541e3b27ce719e2b69 295 Pfam PF00665 Integrase core domain 127 242 4.2E-30 T 10-11-2016 IPR001584 Integrase, catalytic core GO:0015074 A4G23_RS24455 1cf12c82898162dd07cb50b6a93d93de 419 SUPERFAMILY SSF53383 6 363 3.07E-30 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS24455 1cf12c82898162dd07cb50b6a93d93de 419 Pfam PF00155 Aminotransferase class I and II 45 210 1.3E-8 T 10-11-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4G23_RS24455 1cf12c82898162dd07cb50b6a93d93de 419 Gene3D G3DSA:3.40.640.10 44 214 6.0E-19 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS14440 1268757d991ea245a0abcacf20b6386e 296 SUPERFAMILY SSF46894 206 279 1.16E-9 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS14440 1268757d991ea245a0abcacf20b6386e 296 SMART SM00421 216 273 8.6E-5 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS14440 1268757d991ea245a0abcacf20b6386e 296 Gene3D G3DSA:1.10.10.10 217 279 6.9E-10 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS23160 912b047bad7d99132c00bd7da489f6ff 265 Gene3D G3DSA:3.40.50.300 23 228 3.1E-63 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS23160 912b047bad7d99132c00bd7da489f6ff 265 SUPERFAMILY SSF52540 24 239 8.42E-63 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS23160 912b047bad7d99132c00bd7da489f6ff 265 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS23160 912b047bad7d99132c00bd7da489f6ff 265 Pfam PF00005 ABC transporter 41 173 7.9E-28 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS23160 912b047bad7d99132c00bd7da489f6ff 265 SMART SM00382 50 223 1.7E-14 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS20235 a5c9099183cdd433d2628927b85b6a74 167 Pfam PF05331 Protein of unknown function (DUF742) 55 167 1.1E-39 T 10-11-2016 IPR007995 Protein of unknown function DUF742 A4G23_RS03095 488c45e32cd53139b076f7e91cfa87a7 202 Pfam PF01066 CDP-alcohol phosphatidyltransferase 16 85 6.8E-15 T 10-11-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A4G23_RS03095 488c45e32cd53139b076f7e91cfa87a7 202 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 63 85 - T 10-11-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A4G23_RS03095 488c45e32cd53139b076f7e91cfa87a7 202 PIRSF PIRSF000847 11 202 4.8E-44 T 10-11-2016 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668 A4G23_RS04330 67c7b39e517f66bef3d23bbb9f72a239 295 PIRSF PIRSF017269 7 277 1.3E-85 T 10-11-2016 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829 A4G23_RS04330 67c7b39e517f66bef3d23bbb9f72a239 295 Pfam PF14801 tRNA methyltransferase complex GCD14 subunit N-term 11 61 2.8E-28 T 10-11-2016 A4G23_RS04330 67c7b39e517f66bef3d23bbb9f72a239 295 Gene3D G3DSA:3.40.50.150 77 283 4.2E-66 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS04330 67c7b39e517f66bef3d23bbb9f72a239 295 Gene3D G3DSA:3.10.330.20 2 75 8.1E-33 T 10-11-2016 A4G23_RS04330 67c7b39e517f66bef3d23bbb9f72a239 295 SUPERFAMILY SSF53335 13 266 2.81E-70 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS04330 67c7b39e517f66bef3d23bbb9f72a239 295 Pfam PF08704 tRNA methyltransferase complex GCD14 subunit 80 244 1.1E-20 T 10-11-2016 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829 A4G23_RS00935 7db18d76b4d2fc89a4c87eeb2d8dc82f 182 SUPERFAMILY SSF46785 2 176 1.61E-34 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS00935 7db18d76b4d2fc89a4c87eeb2d8dc82f 182 Pfam PF10400 Virulence activator alpha C-term 93 175 4.3E-23 T 10-11-2016 IPR018309 Transcription regulator PadR, C-terminal A4G23_RS00935 7db18d76b4d2fc89a4c87eeb2d8dc82f 182 Pfam PF03551 Transcriptional regulator PadR-like family 7 82 1.4E-10 T 10-11-2016 IPR005149 Transcription regulator PadR, N-terminal A4G23_RS00935 7db18d76b4d2fc89a4c87eeb2d8dc82f 182 Gene3D G3DSA:1.10.10.10 1 86 6.0E-23 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS15035 d622d8b8eda0c88bce28f2f1cb4fd4ef 203 Pfam PF06236 Tyrosinase co-factor MelC1 84 173 3.2E-26 T 10-11-2016 IPR010928 Tyrosinase co-factor MelC1 GO:0005507|GO:0042438 A4G23_RS09330 f9c318c6e4f6e6cf9e668f9c38eb3ba5 338 SUPERFAMILY SSF48452 12 127 2.47E-5 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS09330 f9c318c6e4f6e6cf9e668f9c38eb3ba5 338 Pfam PF02810 SEC-C motif 317 335 1.5E-5 T 10-11-2016 IPR004027 SEC-C motif A4G23_RS09330 f9c318c6e4f6e6cf9e668f9c38eb3ba5 338 Gene3D G3DSA:1.25.40.10 34 128 8.0E-4 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS09330 f9c318c6e4f6e6cf9e668f9c38eb3ba5 338 Gene3D G3DSA:1.25.40.10 290 307 8.0E-4 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS19525 5a46a760c5b137c46817fa3fada0b10e 212 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 17 153 2.4E-15 T 10-11-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily A4G23_RS19525 5a46a760c5b137c46817fa3fada0b10e 212 SUPERFAMILY SSF52788 175 203 1.96E-22 T 10-11-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily A4G23_RS19525 5a46a760c5b137c46817fa3fada0b10e 212 SUPERFAMILY SSF52788 14 137 1.96E-22 T 10-11-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily A4G23_RS19525 5a46a760c5b137c46817fa3fada0b10e 212 Gene3D G3DSA:3.40.50.270 15 128 1.8E-30 T 10-11-2016 A4G23_RS19525 5a46a760c5b137c46817fa3fada0b10e 212 Gene3D G3DSA:3.40.50.270 168 205 1.8E-30 T 10-11-2016 A4G23_RS19525 5a46a760c5b137c46817fa3fada0b10e 212 SMART SM00226 15 204 1.9E-6 T 10-11-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily A4G23_RS03045 636257a5605d8e800615625fccb9fe9d 125 SUPERFAMILY SSF50346 6 106 5.65E-24 T 10-11-2016 IPR011033 PRC-barrel-like A4G23_RS03045 636257a5605d8e800615625fccb9fe9d 125 Pfam PF05239 PRC-barrel domain 10 74 1.5E-9 T 10-11-2016 IPR027275 PRC-barrel domain A4G23_RS03045 636257a5605d8e800615625fccb9fe9d 125 Gene3D G3DSA:3.90.50.10 1 69 1.8E-4 T 10-11-2016 IPR014747 Bacterial photosynthetic reaction centre, H-chain, C-terminal GO:0019684|GO:0030077|GO:0045156 A4G23_RS22225 40344715084f285e4b0c79ba055e9f2c 392 Gene3D G3DSA:3.40.50.1110 162 378 3.1E-11 T 10-11-2016 IPR013830 SGNH hydrolase-type esterase domain A4G23_RS22225 40344715084f285e4b0c79ba055e9f2c 392 SUPERFAMILY SSF52266 172 379 2.9E-26 T 10-11-2016 IPR013830 SGNH hydrolase-type esterase domain A4G23_RS22225 40344715084f285e4b0c79ba055e9f2c 392 Pfam PF14606 GDSL-like Lipase/Acylhydrolase family 178 277 7.9E-13 T 10-11-2016 IPR013830 SGNH hydrolase-type esterase domain A4G23_RS26495 6e9e77686efb0486a7c7e41d343fc473 140 Pfam PF04965 Gene 25-like lysozyme 27 116 1.1E-18 T 10-11-2016 IPR007048 GpW/Gp25/anti-adapter protein IraD A4G23_RS26495 6e9e77686efb0486a7c7e41d343fc473 140 Gene3D G3DSA:3.10.450.40 2 127 1.8E-35 T 10-11-2016 A4G23_RS26495 6e9e77686efb0486a7c7e41d343fc473 140 SUPERFAMILY SSF160719 24 127 1.83E-24 T 10-11-2016 A4G23_RS23030 9c8bf6772dfa1ad6bfb943b3f853b56a 318 Pfam PF01872 RibD C-terminal domain 84 281 8.8E-31 T 10-11-2016 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 A4G23_RS23030 9c8bf6772dfa1ad6bfb943b3f853b56a 318 SUPERFAMILY SSF53597 84 300 4.98E-38 T 10-11-2016 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 A4G23_RS23030 9c8bf6772dfa1ad6bfb943b3f853b56a 318 Gene3D G3DSA:3.40.430.10 76 301 3.4E-62 T 10-11-2016 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 A4G23_RS21025 a0570f8ad0c522a77af8bc9689428879 238 TIGRFAM TIGR02170 thyX: thymidylate synthase, flavin-dependent 11 230 2.3E-62 T 10-11-2016 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 A4G23_RS21025 a0570f8ad0c522a77af8bc9689428879 238 Hamap MF_01408 Thymidylate synthase ThyX [thyX]. 7 238 27.271 T 10-11-2016 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 A4G23_RS21025 a0570f8ad0c522a77af8bc9689428879 238 SUPERFAMILY SSF69796 6 231 2.62E-52 T 10-11-2016 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 A4G23_RS21025 a0570f8ad0c522a77af8bc9689428879 238 Pfam PF02511 Thymidylate synthase complementing protein 12 224 8.8E-50 T 10-11-2016 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 A4G23_RS16195 0109934b73a9d79128899b28665fdab1 412 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 90 138 3.0E-14 T 10-11-2016 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16195 0109934b73a9d79128899b28665fdab1 412 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 31 150 3.6E-32 T 10-11-2016 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16195 0109934b73a9d79128899b28665fdab1 412 SUPERFAMILY SSF143243 18 157 3.53E-37 T 10-11-2016 A4G23_RS16195 0109934b73a9d79128899b28665fdab1 412 PRINTS PR01217 Proline rich extensin signature 230 251 1.7E-11 T 10-11-2016 A4G23_RS16195 0109934b73a9d79128899b28665fdab1 412 PRINTS PR01217 Proline rich extensin signature 253 269 1.7E-11 T 10-11-2016 A4G23_RS16195 0109934b73a9d79128899b28665fdab1 412 PRINTS PR01217 Proline rich extensin signature 342 367 1.7E-11 T 10-11-2016 A4G23_RS12485 f4792813c286d8768ac025444f0a5b75 607 Pfam PF00149 Calcineurin-like phosphoesterase 62 317 2.7E-5 T 10-11-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 A4G23_RS12485 f4792813c286d8768ac025444f0a5b75 607 Pfam PF02872 5'-nucleotidase, C-terminal domain 397 565 6.0E-41 T 10-11-2016 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 A4G23_RS12485 f4792813c286d8768ac025444f0a5b75 607 SUPERFAMILY SSF56300 53 393 4.32E-67 T 10-11-2016 IPR029052 Metallo-dependent phosphatase-like A4G23_RS12485 f4792813c286d8768ac025444f0a5b75 607 Gene3D G3DSA:3.90.780.10 397 605 7.6E-51 T 10-11-2016 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 A4G23_RS12485 f4792813c286d8768ac025444f0a5b75 607 Gene3D G3DSA:3.60.21.10 52 391 4.8E-78 T 10-11-2016 IPR029052 Metallo-dependent phosphatase-like A4G23_RS12485 f4792813c286d8768ac025444f0a5b75 607 PRINTS PR01607 Apyrase family signature 540 559 2.1E-18 T 10-11-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 A4G23_RS12485 f4792813c286d8768ac025444f0a5b75 607 PRINTS PR01607 Apyrase family signature 55 73 2.1E-18 T 10-11-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 A4G23_RS12485 f4792813c286d8768ac025444f0a5b75 607 PRINTS PR01607 Apyrase family signature 464 487 2.1E-18 T 10-11-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 A4G23_RS12485 f4792813c286d8768ac025444f0a5b75 607 PRINTS PR01607 Apyrase family signature 300 323 2.1E-18 T 10-11-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 A4G23_RS12485 f4792813c286d8768ac025444f0a5b75 607 SUPERFAMILY SSF55816 395 605 1.31E-48 T 10-11-2016 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 A4G23_RS25950 fbfdc50fc5d6855545cee8fae9912ca5 147 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 28 143 2.5E-33 T 10-11-2016 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III A4G23_RS04925 7029a737a7b69e039219e112b2f27002 600 SUPERFAMILY SSF48208 193 593 6.43E-112 T 10-11-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 A4G23_RS04925 7029a737a7b69e039219e112b2f27002 600 Gene3D G3DSA:1.50.10.10 216 593 4.3E-85 T 10-11-2016 IPR012341 Six-hairpin glycosidase GO:0003824 A4G23_RS04925 7029a737a7b69e039219e112b2f27002 600 Pfam PF00723 Glycosyl hydrolases family 15 220 589 7.6E-75 T 10-11-2016 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: R-HSA-70221 A4G23_RS23630 a514a838cc71323a13111ed7b8a02572 221 Gene3D G3DSA:1.10.10.10 165 220 2.6E-25 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS23630 a514a838cc71323a13111ed7b8a02572 221 SUPERFAMILY SSF52172 8 132 4.7E-34 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS23630 a514a838cc71323a13111ed7b8a02572 221 Gene3D G3DSA:3.40.50.2300 7 164 8.4E-39 T 10-11-2016 A4G23_RS23630 a514a838cc71323a13111ed7b8a02572 221 Pfam PF00196 Bacterial regulatory proteins, luxR family 158 213 2.5E-18 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS23630 a514a838cc71323a13111ed7b8a02572 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 173 4.6E-14 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS23630 a514a838cc71323a13111ed7b8a02572 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 189 201 4.6E-14 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS23630 a514a838cc71323a13111ed7b8a02572 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 189 4.6E-14 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS23630 a514a838cc71323a13111ed7b8a02572 221 Pfam PF00072 Response regulator receiver domain 11 122 3.2E-28 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS23630 a514a838cc71323a13111ed7b8a02572 221 SMART SM00421 156 213 5.3E-24 T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS23630 a514a838cc71323a13111ed7b8a02572 221 SMART SM00448 9 122 2.2E-31 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS23630 a514a838cc71323a13111ed7b8a02572 221 ProSitePatterns PS00622 LuxR-type HTH domain signature. 173 200 - T 10-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4G23_RS23630 a514a838cc71323a13111ed7b8a02572 221 SUPERFAMILY SSF46894 151 220 7.14E-22 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS17030 3b3cf40c58719a5343cf54347af23f1c 271 Pfam PF01909 Nucleotidyltransferase domain 5 48 2.9E-6 T 10-11-2016 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 A4G23_RS17030 3b3cf40c58719a5343cf54347af23f1c 271 Gene3D G3DSA:3.30.460.10 3 62 2.6E-9 T 10-11-2016 A4G23_RS17030 3b3cf40c58719a5343cf54347af23f1c 271 SUPERFAMILY SSF81301 2 74 1.89E-9 T 10-11-2016 A4G23_RS08000 83dc1e4494e4d7d10262b44a0163c513 704 Gene3D G3DSA:1.10.443.10 345 537 3.3E-5 T 10-11-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 A4G23_RS08000 83dc1e4494e4d7d10262b44a0163c513 704 SUPERFAMILY SSF56349 335 536 3.24E-7 T 10-11-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A4G23_RS19890 599b187bb64850d702db64a9bbcc013c 255 SUPERFAMILY SSF52096 2 250 2.34E-81 T 10-11-2016 IPR029045 ClpP/crotonase-like domain A4G23_RS19890 599b187bb64850d702db64a9bbcc013c 255 Gene3D G3DSA:3.90.226.10 2 247 6.5E-86 T 10-11-2016 IPR029045 ClpP/crotonase-like domain A4G23_RS19890 599b187bb64850d702db64a9bbcc013c 255 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 96 116 - T 10-11-2016 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 A4G23_RS19890 599b187bb64850d702db64a9bbcc013c 255 Pfam PF00378 Enoyl-CoA hydratase/isomerase 7 249 1.5E-69 T 10-11-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 A4G23_RS15865 937660ea4394208b2992ae0dc6f83fb9 145 Pfam PF13396 Phospholipase_D-nuclease N-terminal 12 56 1.7E-12 T 10-11-2016 IPR027379 Cardiolipin synthase N-terminal A4G23_RS21680 7b419a12e7b62588d98e7a58269c28cf 346 Gene3D G3DSA:3.40.50.1100 32 131 2.6E-18 T 10-11-2016 A4G23_RS21680 7b419a12e7b62588d98e7a58269c28cf 346 Gene3D G3DSA:3.40.50.1100 132 299 1.8E-40 T 10-11-2016 A4G23_RS21680 7b419a12e7b62588d98e7a58269c28cf 346 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 6 271 2.1E-43 T 10-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4G23_RS21680 7b419a12e7b62588d98e7a58269c28cf 346 SUPERFAMILY SSF53686 5 308 1.11E-60 T 10-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4G23_RS15360 3e207cb28bca1aa960b03ad86c0a6fb1 201 Pfam PF13671 AAA domain 2 139 9.6E-9 T 10-11-2016 A4G23_RS15360 3e207cb28bca1aa960b03ad86c0a6fb1 201 SUPERFAMILY SSF52540 1 171 3.04E-13 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS15360 3e207cb28bca1aa960b03ad86c0a6fb1 201 Gene3D G3DSA:3.40.50.300 2 169 9.4E-7 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS18070 67c6c835aaaba1511fc37b8c76292283 149 Pfam PF01042 Endoribonuclease L-PSP 30 147 4.4E-29 T 10-11-2016 IPR006175 YjgF/YER057c/UK114 family A4G23_RS18070 67c6c835aaaba1511fc37b8c76292283 149 SUPERFAMILY SSF55298 21 148 1.73E-35 T 10-11-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like A4G23_RS18070 67c6c835aaaba1511fc37b8c76292283 149 Gene3D G3DSA:3.30.1330.40 20 148 7.4E-38 T 10-11-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like A4G23_RS17725 3390bd171783dc5bfac0d1c204373770 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 3.3E-9 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS17725 3390bd171783dc5bfac0d1c204373770 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 3.3E-9 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS17725 3390bd171783dc5bfac0d1c204373770 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 3.3E-9 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS17725 3390bd171783dc5bfac0d1c204373770 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 4.8E-37 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS17725 3390bd171783dc5bfac0d1c204373770 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 4.8E-37 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS17725 3390bd171783dc5bfac0d1c204373770 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 4.8E-37 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS17725 3390bd171783dc5bfac0d1c204373770 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 4.8E-37 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS17725 3390bd171783dc5bfac0d1c204373770 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 4.8E-37 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS17725 3390bd171783dc5bfac0d1c204373770 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 4.8E-37 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS17725 3390bd171783dc5bfac0d1c204373770 243 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 242 1.4E-60 T 10-11-2016 A4G23_RS17725 3390bd171783dc5bfac0d1c204373770 243 SUPERFAMILY SSF51735 3 242 5.83E-73 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS17725 3390bd171783dc5bfac0d1c204373770 243 Gene3D G3DSA:3.40.50.720 3 242 6.6E-76 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS17725 3390bd171783dc5bfac0d1c204373770 243 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 10-11-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4G23_RS17725 3390bd171783dc5bfac0d1c204373770 243 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2 182 2.6E-6 T 10-11-2016 A4G23_RS14455 223f34e519142fe929094e2f4e1bffcb 137 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 14 134 3.9E-23 T 10-11-2016 IPR019920 F420-binding domain, putative A4G23_RS14455 223f34e519142fe929094e2f4e1bffcb 137 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 12 99 6.3E-12 T 10-11-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 A4G23_RS14455 223f34e519142fe929094e2f4e1bffcb 137 Gene3D G3DSA:2.30.110.10 13 135 3.6E-32 T 10-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 A4G23_RS14455 223f34e519142fe929094e2f4e1bffcb 137 SUPERFAMILY SSF50475 13 135 3.93E-27 T 10-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 A4G23_RS12170 c585e050d69cf136f214800640e5400f 245 Pfam PF10099 Anti-sigma-K factor rskA 58 239 5.1E-31 T 10-11-2016 IPR018764 Anti-sigma K factor RskA GO:0005886|GO:0016021 A4G23_RS12170 c585e050d69cf136f214800640e5400f 245 Pfam PF13490 Putative zinc-finger 12 37 2.3E-6 T 10-11-2016 IPR027383 Putative zinc-finger A4G23_RS06385 8ba6c3e1ec30e7a8d5aba5e14026cf5d 210 Pfam PF00174 Oxidoreductase molybdopterin binding domain 33 181 2.0E-28 T 10-11-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 A4G23_RS06385 8ba6c3e1ec30e7a8d5aba5e14026cf5d 210 Gene3D G3DSA:3.90.420.10 12 199 5.2E-46 T 10-11-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 A4G23_RS06385 8ba6c3e1ec30e7a8d5aba5e14026cf5d 210 SUPERFAMILY SSF56524 15 203 4.71E-54 T 10-11-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 A4G23_RS26600 fbabcb4af60e59429dc70de148d27fa5 286 Pfam PF01925 Sulfite exporter TauE/SafE 7 241 7.5E-53 T 10-11-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 A4G23_RS18055 e9928442b11869792f389af43d790ab6 293 Pfam PF00294 pfkB family carbohydrate kinase 10 289 8.2E-47 T 10-11-2016 IPR011611 Carbohydrate kinase PfkB A4G23_RS18055 e9928442b11869792f389af43d790ab6 293 SUPERFAMILY SSF53613 1 291 4.42E-63 T 10-11-2016 IPR029056 Ribokinase-like A4G23_RS18055 e9928442b11869792f389af43d790ab6 293 Gene3D G3DSA:3.40.1190.20 1 291 1.9E-86 T 10-11-2016 IPR029056 Ribokinase-like A4G23_RS18010 cefeddfd21fc30b431416ddb6d734c01 285 SMART SM00530 8 80 1.9E-10 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS18010 cefeddfd21fc30b431416ddb6d734c01 285 Pfam PF13560 Helix-turn-helix domain 5 83 7.6E-15 T 10-11-2016 A4G23_RS18010 cefeddfd21fc30b431416ddb6d734c01 285 SUPERFAMILY SSF47413 19 79 2.62E-11 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS18010 cefeddfd21fc30b431416ddb6d734c01 285 Gene3D G3DSA:1.10.260.40 3 79 2.3E-21 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS07820 f6f58ed601166e007954688c381080ef 142 Pfam PF01475 Ferric uptake regulator family 10 126 1.1E-31 T 10-11-2016 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 A4G23_RS07820 f6f58ed601166e007954688c381080ef 142 Gene3D G3DSA:1.10.10.10 10 78 7.3E-20 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS07820 f6f58ed601166e007954688c381080ef 142 SUPERFAMILY SSF46785 10 131 2.83E-34 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS07160 4f25bd666bc20287bf5722c501a40d76 244 Pfam PF08241 Methyltransferase domain 18 121 3.9E-23 T 10-11-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 A4G23_RS07160 4f25bd666bc20287bf5722c501a40d76 244 SUPERFAMILY SSF53335 9 236 3.68E-42 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS07160 4f25bd666bc20287bf5722c501a40d76 244 Gene3D G3DSA:3.40.50.150 8 236 1.5E-48 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS01875 68edd783f3756447153f851d1293a70b 340 SUPERFAMILY SSF159774 59 338 3.92E-76 T 10-11-2016 IPR023158 YerB-like domain A4G23_RS01875 68edd783f3756447153f851d1293a70b 340 Gene3D G3DSA:3.50.90.10 48 338 5.9E-76 T 10-11-2016 IPR023158 YerB-like domain A4G23_RS01875 68edd783f3756447153f851d1293a70b 340 Pfam PF11258 Protein of unknown function (DUF3048) 63 335 5.6E-59 T 10-11-2016 IPR021416 Protein of unknown function DUF3048 A4G23_RS18275 f55e9b8af7af33586995267abb0c7fed 246 Gene3D G3DSA:3.30.420.40 106 244 1.8E-40 T 10-11-2016 A4G23_RS18275 f55e9b8af7af33586995267abb0c7fed 246 SUPERFAMILY SSF53067 1 244 3.01E-40 T 10-11-2016 A4G23_RS18275 f55e9b8af7af33586995267abb0c7fed 246 Gene3D G3DSA:3.30.420.40 2 105 1.1E-42 T 10-11-2016 A4G23_RS18275 f55e9b8af7af33586995267abb0c7fed 246 Pfam PF00480 ROK family 4 160 5.1E-15 T 10-11-2016 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A4G23_RS15980 040d3b2513ea344db90b62a129cf1611 67 SMART SM00357 3 67 3.9E-30 T 10-11-2016 IPR011129 Cold shock protein GO:0003676 A4G23_RS15980 040d3b2513ea344db90b62a129cf1611 67 PRINTS PR00050 Cold shock protein signature 25 34 8.6E-18 T 10-11-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4G23_RS15980 040d3b2513ea344db90b62a129cf1611 67 PRINTS PR00050 Cold shock protein signature 4 19 8.6E-18 T 10-11-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4G23_RS15980 040d3b2513ea344db90b62a129cf1611 67 PRINTS PR00050 Cold shock protein signature 40 58 8.6E-18 T 10-11-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4G23_RS15980 040d3b2513ea344db90b62a129cf1611 67 SUPERFAMILY SSF50249 1 66 1.48E-25 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS15980 040d3b2513ea344db90b62a129cf1611 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 10-11-2016 IPR019844 Cold-shock conserved site A4G23_RS15980 040d3b2513ea344db90b62a129cf1611 67 Gene3D G3DSA:2.40.50.140 1 65 7.3E-32 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS15980 040d3b2513ea344db90b62a129cf1611 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 2.0E-31 T 10-11-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4G23_RS15980 040d3b2513ea344db90b62a129cf1611 67 PIRSF PIRSF002599 1 67 1.9E-25 T 10-11-2016 IPR012156 Cold shock, CspA GO:0003676 A4G23_RS02590 c00512e165ceaa5e2882593a3a433b6c 114 SUPERFAMILY SSF54593 8 112 7.75E-17 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS02590 c00512e165ceaa5e2882593a3a433b6c 114 Gene3D G3DSA:3.10.180.10 4 112 1.2E-14 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS02590 c00512e165ceaa5e2882593a3a433b6c 114 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 12 111 6.9E-5 T 10-11-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4G23_RS24255 884da6f5113603f73ea1b84c06a2d3eb 170 Gene3D G3DSA:3.40.630.30 13 169 1.4E-32 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS24255 884da6f5113603f73ea1b84c06a2d3eb 170 Pfam PF00583 Acetyltransferase (GNAT) family 66 142 2.3E-10 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS24255 884da6f5113603f73ea1b84c06a2d3eb 170 SUPERFAMILY SSF55729 15 169 1.95E-24 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS22170 722a373dabdb8e56f9ca8109eee0758c 332 Gene3D G3DSA:3.40.50.1100 128 295 2.4E-25 T 10-11-2016 A4G23_RS22170 722a373dabdb8e56f9ca8109eee0758c 332 Gene3D G3DSA:3.40.50.1100 28 127 3.5E-19 T 10-11-2016 A4G23_RS22170 722a373dabdb8e56f9ca8109eee0758c 332 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 6 273 8.4E-35 T 10-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4G23_RS22170 722a373dabdb8e56f9ca8109eee0758c 332 SUPERFAMILY SSF53686 6 295 4.58E-48 T 10-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4G23_RS01300 a77a7bd9ed7f7f79df3f4f2beb300ed7 496 SUPERFAMILY SSF55874 247 367 7.86E-15 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS01300 a77a7bd9ed7f7f79df3f4f2beb300ed7 496 Gene3D G3DSA:3.30.565.10 255 365 1.0E-14 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS01300 a77a7bd9ed7f7f79df3f4f2beb300ed7 496 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 256 364 3.4E-6 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS01300 a77a7bd9ed7f7f79df3f4f2beb300ed7 496 SMART SM00387 252 366 1.2E-4 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS07340 db4ecf94337bc1c9aca67972c86d52cf 354 SMART SM00507 245 308 8.1E-6 T 10-11-2016 IPR003615 HNH nuclease A4G23_RS07340 db4ecf94337bc1c9aca67972c86d52cf 354 Pfam PF01844 HNH endonuclease 259 313 2.3E-10 T 10-11-2016 IPR002711 HNH endonuclease GO:0003676|GO:0004519 A4G23_RS15935 31d108fb2f6856c05ceca9a725301690 136 Pfam PF01609 Transposase DDE domain 2 125 3.5E-14 T 10-11-2016 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4G23_RS22630 0ed727a4335bb93df5364e7148e296aa 281 Pfam PF00656 Caspase domain 19 265 7.3E-24 T 10-11-2016 A4G23_RS22630 0ed727a4335bb93df5364e7148e296aa 281 Gene3D G3DSA:3.40.50.1460 6 270 2.3E-52 T 10-11-2016 IPR029030 Caspase-like domain A4G23_RS22630 0ed727a4335bb93df5364e7148e296aa 281 SUPERFAMILY SSF52129 199 237 1.46E-8 T 10-11-2016 IPR029030 Caspase-like domain A4G23_RS22630 0ed727a4335bb93df5364e7148e296aa 281 SUPERFAMILY SSF52129 20 147 1.46E-8 T 10-11-2016 IPR029030 Caspase-like domain A4G23_RS17420 f436e22f5e247e7446baae58aa4b49d3 431 Gene3D G3DSA:1.20.1250.20 31 207 1.2E-23 T 10-11-2016 A4G23_RS17420 f436e22f5e247e7446baae58aa4b49d3 431 Gene3D G3DSA:1.20.1250.20 242 418 6.8E-14 T 10-11-2016 A4G23_RS17420 f436e22f5e247e7446baae58aa4b49d3 431 Pfam PF07690 Major Facilitator Superfamily 41 385 3.0E-31 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS17420 f436e22f5e247e7446baae58aa4b49d3 431 SUPERFAMILY SSF103473 26 425 2.88E-46 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS24905 c0fcdf1adfdc42fe2ec9771debc3dd18 352 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 99 113 - T 10-11-2016 IPR000092 Polyprenyl synthetase GO:0008299 A4G23_RS24905 c0fcdf1adfdc42fe2ec9771debc3dd18 352 Pfam PF00348 Polyprenyl synthetase 60 286 3.0E-51 T 10-11-2016 IPR000092 Polyprenyl synthetase GO:0008299 A4G23_RS24905 c0fcdf1adfdc42fe2ec9771debc3dd18 352 SUPERFAMILY SSF48576 28 351 4.96E-75 T 10-11-2016 IPR008949 Isoprenoid synthase domain A4G23_RS24905 c0fcdf1adfdc42fe2ec9771debc3dd18 352 Gene3D G3DSA:1.10.600.10 60 351 8.8E-81 T 10-11-2016 IPR008949 Isoprenoid synthase domain A4G23_RS01405 5ab193ff2421d5b98cfe7a5f826666f0 277 SUPERFAMILY SSF161098 8 277 7.33E-72 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS01405 5ab193ff2421d5b98cfe7a5f826666f0 277 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 269 5.1E-20 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS01405 5ab193ff2421d5b98cfe7a5f826666f0 277 Gene3D G3DSA:1.10.3720.10 13 264 1.4E-63 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS14705 e55acc05204bf8fb2392c952411a4090 239 Pfam PF07729 FCD domain 114 212 3.8E-8 T 10-11-2016 IPR011711 GntR, C-terminal A4G23_RS14705 e55acc05204bf8fb2392c952411a4090 239 SUPERFAMILY SSF46785 8 78 5.52E-17 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS14705 e55acc05204bf8fb2392c952411a4090 239 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 74 2.1E-17 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS14705 e55acc05204bf8fb2392c952411a4090 239 Gene3D G3DSA:1.20.120.530 101 218 3.6E-11 T 10-11-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal A4G23_RS14705 e55acc05204bf8fb2392c952411a4090 239 SUPERFAMILY SSF48008 108 220 4.97E-11 T 10-11-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal A4G23_RS14705 e55acc05204bf8fb2392c952411a4090 239 SMART SM00345 16 74 9.8E-14 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS14705 e55acc05204bf8fb2392c952411a4090 239 Gene3D G3DSA:1.10.10.10 4 75 4.8E-22 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS03845 4b2bcd285efa4b660b104e0193b59eaa 173 Gene3D G3DSA:3.40.30.10 8 166 8.8E-34 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS03845 4b2bcd285efa4b660b104e0193b59eaa 173 Pfam PF01323 DSBA-like thioredoxin domain 15 161 2.5E-22 T 10-11-2016 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 A4G23_RS03845 4b2bcd285efa4b660b104e0193b59eaa 173 SUPERFAMILY SSF52833 10 163 7.72E-29 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS18020 70576e9599021e62f7d34dcd08998f14 229 Pfam PF03006 Haemolysin-III related 21 218 6.8E-43 T 10-11-2016 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 A4G23_RS12450 5d538d527a2e8db04cb72b97ec5ff02b 84 SUPERFAMILY SSF54285 5 84 2.8E-13 T 10-11-2016 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp A4G23_RS12450 5d538d527a2e8db04cb72b97ec5ff02b 84 Gene3D G3DSA:3.10.20.30 5 84 7.5E-13 T 10-11-2016 IPR012675 Beta-grasp domain A4G23_RS12450 5d538d527a2e8db04cb72b97ec5ff02b 84 Pfam PF02597 ThiS family 6 84 1.1E-10 T 10-11-2016 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 A4G23_RS07210 69ad95ffc5cf2b8985b0136a02b69f1c 234 Gene3D G3DSA:3.40.50.150 18 232 5.3E-64 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS07210 69ad95ffc5cf2b8985b0136a02b69f1c 234 SUPERFAMILY SSF53335 48 232 2.25E-41 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS07210 69ad95ffc5cf2b8985b0136a02b69f1c 234 Pfam PF01596 O-methyltransferase 44 217 1.1E-37 T 10-11-2016 IPR002935 O-methyltransferase, family 3 GO:0008171 A4G23_RS15080 2c4332a7f15def89747529d819dcf4a4 639 Pfam PF03023 MviN-like protein 331 559 1.2E-31 T 10-11-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ A4G23_RS15080 2c4332a7f15def89747529d819dcf4a4 639 Pfam PF03023 MviN-like protein 51 240 8.3E-24 T 10-11-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ A4G23_RS15080 2c4332a7f15def89747529d819dcf4a4 639 PRINTS PR01806 Virulence factor MviN signature 56 75 7.1E-6 T 10-11-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ A4G23_RS15080 2c4332a7f15def89747529d819dcf4a4 639 PRINTS PR01806 Virulence factor MviN signature 75 91 7.1E-6 T 10-11-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ A4G23_RS15080 2c4332a7f15def89747529d819dcf4a4 639 PRINTS PR01806 Virulence factor MviN signature 158 182 7.1E-6 T 10-11-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ A4G23_RS15080 2c4332a7f15def89747529d819dcf4a4 639 PRINTS PR01806 Virulence factor MviN signature 182 203 7.1E-6 T 10-11-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ A4G23_RS15635 6d4c4a92718c65b5deee1e87d3efe635 555 Gene3D G3DSA:3.40.50.10090 278 400 1.6E-40 T 10-11-2016 A4G23_RS15635 6d4c4a92718c65b5deee1e87d3efe635 555 Gene3D G3DSA:3.40.50.10090 408 528 4.4E-34 T 10-11-2016 A4G23_RS15635 6d4c4a92718c65b5deee1e87d3efe635 555 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 18 228 4.1E-33 T 10-11-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A4G23_RS15635 6d4c4a92718c65b5deee1e87d3efe635 555 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 22 36 - T 10-11-2016 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 A4G23_RS15635 6d4c4a92718c65b5deee1e87d3efe635 555 Gene3D G3DSA:3.40.1010.10 17 135 6.4E-29 T 10-11-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A4G23_RS15635 6d4c4a92718c65b5deee1e87d3efe635 555 SUPERFAMILY SSF69618 273 523 7.46E-66 T 10-11-2016 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4G23_RS15635 6d4c4a92718c65b5deee1e87d3efe635 555 Gene3D G3DSA:3.30.950.10 137 277 5.5E-30 T 10-11-2016 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A4G23_RS15635 6d4c4a92718c65b5deee1e87d3efe635 555 SUPERFAMILY SSF53790 16 275 7.2E-44 T 10-11-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A4G23_RS15635 6d4c4a92718c65b5deee1e87d3efe635 555 Pfam PF02602 Uroporphyrinogen-III synthase HemD 287 517 1.9E-63 T 10-11-2016 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4G23_RS11165 c6c2a3a40c18256502b5555f9aacf6d0 528 Gene3D G3DSA:3.40.462.10 311 484 1.1E-22 T 10-11-2016 IPR016170 Vanillyl-alcohol oxidase/Cytokinin dehydrogenase C-terminal domain KEGG: 00908+1.5.99.12 A4G23_RS11165 c6c2a3a40c18256502b5555f9aacf6d0 528 Gene3D G3DSA:1.10.45.10 509 525 3.6E-5 T 10-11-2016 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 A4G23_RS11165 c6c2a3a40c18256502b5555f9aacf6d0 528 SUPERFAMILY SSF55103 245 368 1.79E-16 T 10-11-2016 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 A4G23_RS11165 c6c2a3a40c18256502b5555f9aacf6d0 528 SUPERFAMILY SSF55103 399 525 1.79E-16 T 10-11-2016 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 A4G23_RS11165 c6c2a3a40c18256502b5555f9aacf6d0 528 SUPERFAMILY SSF56176 41 257 4.02E-40 T 10-11-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 A4G23_RS11165 c6c2a3a40c18256502b5555f9aacf6d0 528 Pfam PF01565 FAD binding domain 79 214 2.2E-26 T 10-11-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 A4G23_RS11165 c6c2a3a40c18256502b5555f9aacf6d0 528 Gene3D G3DSA:3.30.43.10 39 134 4.0E-22 T 10-11-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 A4G23_RS11165 c6c2a3a40c18256502b5555f9aacf6d0 528 Pfam PF02913 FAD linked oxidases, C-terminal domain 411 524 1.8E-5 T 10-11-2016 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 A4G23_RS11165 c6c2a3a40c18256502b5555f9aacf6d0 528 Gene3D G3DSA:3.30.465.10 135 258 1.4E-24 T 10-11-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 A4G23_RS08750 0bc6d17e35653fc167f44449ec8c09ff 429 SUPERFAMILY SSF48256 3 429 3.93E-161 T 10-11-2016 IPR002020 Citrate synthase GO:0046912 A4G23_RS08750 0bc6d17e35653fc167f44449ec8c09ff 429 PIRSF PIRSF001369 37 429 1.8E-157 T 10-11-2016 IPR024176 Citrate synthase, bacterial-type A4G23_RS08750 0bc6d17e35653fc167f44449ec8c09ff 429 Pfam PF00285 Citrate synthase, C-terminal domain 46 412 1.2E-136 T 10-11-2016 IPR002020 Citrate synthase GO:0046912 A4G23_RS08750 0bc6d17e35653fc167f44449ec8c09ff 429 PRINTS PR00143 Citrate synthase signature 241 269 8.5E-54 T 10-11-2016 IPR002020 Citrate synthase GO:0046912 A4G23_RS08750 0bc6d17e35653fc167f44449ec8c09ff 429 PRINTS PR00143 Citrate synthase signature 380 394 8.5E-54 T 10-11-2016 IPR002020 Citrate synthase GO:0046912 A4G23_RS08750 0bc6d17e35653fc167f44449ec8c09ff 429 PRINTS PR00143 Citrate synthase signature 219 234 8.5E-54 T 10-11-2016 IPR002020 Citrate synthase GO:0046912 A4G23_RS08750 0bc6d17e35653fc167f44449ec8c09ff 429 PRINTS PR00143 Citrate synthase signature 165 178 8.5E-54 T 10-11-2016 IPR002020 Citrate synthase GO:0046912 A4G23_RS08750 0bc6d17e35653fc167f44449ec8c09ff 429 PRINTS PR00143 Citrate synthase signature 360 376 8.5E-54 T 10-11-2016 IPR002020 Citrate synthase GO:0046912 A4G23_RS08750 0bc6d17e35653fc167f44449ec8c09ff 429 PRINTS PR00143 Citrate synthase signature 297 317 8.5E-54 T 10-11-2016 IPR002020 Citrate synthase GO:0046912 A4G23_RS08750 0bc6d17e35653fc167f44449ec8c09ff 429 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 14 423 1.0E-184 T 10-11-2016 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 A4G23_RS08750 0bc6d17e35653fc167f44449ec8c09ff 429 ProSitePatterns PS00480 Citrate synthase signature. 304 316 - T 10-11-2016 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 A4G23_RS08750 0bc6d17e35653fc167f44449ec8c09ff 429 Gene3D G3DSA:1.10.230.10 282 374 2.2E-35 T 10-11-2016 IPR016143 Citrate synthase-like, small alpha subdomain Reactome: R-HSA-163765|Reactome: R-HSA-75105 A4G23_RS08750 0bc6d17e35653fc167f44449ec8c09ff 429 Gene3D G3DSA:1.10.580.10 52 281 2.3E-98 T 10-11-2016 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 A4G23_RS06215 5ae876c6da48d266c8d6a9a3e87ce9fb 205 Pfam PF04472 Protein of unknown function (DUF552) 117 188 3.3E-27 T 10-11-2016 IPR007561 Cell division protein SepF/SepF-related GO:0090529 A4G23_RS06215 5ae876c6da48d266c8d6a9a3e87ce9fb 205 Hamap MF_01197 Cell division protein SepF [sepF]. 2 196 22.529 T 10-11-2016 IPR023052 Cell division protein SepF GO:0090529 A4G23_RS10515 5afe484b2c2651f719d16017b3261c5d 1035 Pfam PF14440 Xanthomonas XOO_2897-like deaminase 718 815 4.7E-32 T 10-11-2016 IPR032722 Deaminase, Xanthomonas XOO_2897-like A4G23_RS10515 5afe484b2c2651f719d16017b3261c5d 1035 Pfam PF14435 SUKH-4 immunity protein 853 1029 4.5E-41 T 10-11-2016 IPR025851 SUKH-4 immunity protein A4G23_RS12350 34864155a1b6eb5ace5257cf07dbacbd 736 Pfam PF13245 Part of AAA domain 251 316 1.1E-12 T 10-11-2016 A4G23_RS12350 34864155a1b6eb5ace5257cf07dbacbd 736 SUPERFAMILY SSF52540 495 728 5.88E-45 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS12350 34864155a1b6eb5ace5257cf07dbacbd 736 SUPERFAMILY SSF52540 234 364 5.88E-45 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS12350 34864155a1b6eb5ace5257cf07dbacbd 736 Gene3D G3DSA:3.40.50.300 585 732 3.4E-20 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS12350 34864155a1b6eb5ace5257cf07dbacbd 736 Gene3D G3DSA:3.40.50.300 441 584 1.0E-28 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS12350 34864155a1b6eb5ace5257cf07dbacbd 736 Gene3D G3DSA:3.40.50.300 241 309 1.0E-28 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS17795 8bcd1fe6ca04c4bfda0cfb6a4d534ca1 145 Gene3D G3DSA:3.10.490.10 1 145 1.7E-47 T 10-11-2016 IPR013024 Butirosin biosynthesis, BtrG-like A4G23_RS17795 8bcd1fe6ca04c4bfda0cfb6a4d534ca1 145 SUPERFAMILY SSF110857 1 119 8.37E-15 T 10-11-2016 IPR013024 Butirosin biosynthesis, BtrG-like A4G23_RS17795 8bcd1fe6ca04c4bfda0cfb6a4d534ca1 145 Pfam PF13772 AIG2-like family 59 138 5.1E-21 T 10-11-2016 A4G23_RS00475 0a4cc5be9bf7bc3cbdea29c3bc2ea1fc 85 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 77 19.239 T 10-11-2016 IPR003482 Transcription factor WhiB A4G23_RS00475 0a4cc5be9bf7bc3cbdea29c3bc2ea1fc 85 Pfam PF02467 Transcription factor WhiB 4 72 4.4E-27 T 10-11-2016 IPR003482 Transcription factor WhiB A4G23_RS21205 10debb0ec1c04f2a02c73152035e8c81 261 PIRSF PIRSF039085 17 260 2.3E-112 T 10-11-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 A4G23_RS21205 10debb0ec1c04f2a02c73152035e8c81 261 SMART SM00382 45 232 1.3E-17 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS21205 10debb0ec1c04f2a02c73152035e8c81 261 Gene3D G3DSA:3.40.50.300 20 256 8.3E-86 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS21205 10debb0ec1c04f2a02c73152035e8c81 261 SUPERFAMILY SSF52540 21 254 1.73E-80 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS21205 10debb0ec1c04f2a02c73152035e8c81 261 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS21205 10debb0ec1c04f2a02c73152035e8c81 261 Pfam PF00005 ABC transporter 36 184 5.1E-37 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS21690 d1607b34fc1755585c5660ae1daba756 209 SUPERFAMILY SSF56349 12 188 1.53E-17 T 10-11-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A4G23_RS21690 d1607b34fc1755585c5660ae1daba756 209 Gene3D G3DSA:1.10.443.10 12 191 1.2E-17 T 10-11-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 A4G23_RS21690 d1607b34fc1755585c5660ae1daba756 209 Pfam PF00589 Phage integrase family 14 130 5.2E-8 T 10-11-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A4G23_RS11355 2d50c39b3209f0c372150986b24993e3 249 Gene3D G3DSA:3.40.50.720 3 248 1.9E-76 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS11355 2d50c39b3209f0c372150986b24993e3 249 SUPERFAMILY SSF51735 5 248 2.94E-72 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS11355 2d50c39b3209f0c372150986b24993e3 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 248 9.2E-56 T 10-11-2016 A4G23_RS11355 2d50c39b3209f0c372150986b24993e3 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 1.2E-7 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS11355 2d50c39b3209f0c372150986b24993e3 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 1.2E-7 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS11355 2d50c39b3209f0c372150986b24993e3 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 1.2E-7 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS11355 2d50c39b3209f0c372150986b24993e3 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 3.6E-36 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS11355 2d50c39b3209f0c372150986b24993e3 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 3.6E-36 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS11355 2d50c39b3209f0c372150986b24993e3 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 3.6E-36 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS11355 2d50c39b3209f0c372150986b24993e3 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 3.6E-36 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS11355 2d50c39b3209f0c372150986b24993e3 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 3.6E-36 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS11355 2d50c39b3209f0c372150986b24993e3 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 3.6E-36 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS08070 b5c93ef0643ceae113b204aab51a1621 682 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 592 679 3.7E-11 T 10-11-2016 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain A4G23_RS08070 b5c93ef0643ceae113b204aab51a1621 682 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 354 511 4.8E-8 T 10-11-2016 IPR004474 Cell envelope-related transcriptional attenuator domain A4G23_RS11220 163ece0b6d55bb9edaffe8c66aaeb97f 302 Gene3D G3DSA:3.90.550.10 1 264 2.0E-62 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS11220 163ece0b6d55bb9edaffe8c66aaeb97f 302 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 2 286 6.8E-129 T 10-11-2016 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 A4G23_RS11220 163ece0b6d55bb9edaffe8c66aaeb97f 302 SUPERFAMILY SSF53448 1 286 4.73E-83 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS11220 163ece0b6d55bb9edaffe8c66aaeb97f 302 Pfam PF00483 Nucleotidyl transferase 2 235 8.8E-57 T 10-11-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A4G23_RS15085 2fa434eb90ca6e15604f604b9656edd1 240 Pfam PF01522 Polysaccharide deacetylase 63 195 1.6E-26 T 10-11-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 A4G23_RS15085 2fa434eb90ca6e15604f604b9656edd1 240 Gene3D G3DSA:3.20.20.370 63 202 2.5E-29 T 10-11-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 A4G23_RS15085 2fa434eb90ca6e15604f604b9656edd1 240 SUPERFAMILY SSF88713 25 197 1.85E-35 T 10-11-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A4G23_RS25430 18a1ef9c7aa4b4805f84c7c4f846830a 140 Pfam PF03994 Domain of Unknown Function (DUF350) 14 68 8.8E-13 T 10-11-2016 IPR007140 Protein of unknown function DUF350 A4G23_RS25430 18a1ef9c7aa4b4805f84c7c4f846830a 140 Pfam PF03994 Domain of Unknown Function (DUF350) 85 139 1.2E-15 T 10-11-2016 IPR007140 Protein of unknown function DUF350 A4G23_RS04800 e9f54f25023ccf7afdd4e375439af34c 451 SUPERFAMILY SSF53822 61 432 7.06E-39 T 10-11-2016 IPR028082 Periplasmic binding protein-like I A4G23_RS04800 e9f54f25023ccf7afdd4e375439af34c 451 Pfam PF13458 Periplasmic binding protein 61 428 6.5E-50 T 10-11-2016 IPR028081 Leucine-binding protein domain A4G23_RS04800 e9f54f25023ccf7afdd4e375439af34c 451 Gene3D G3DSA:3.40.50.2300 61 267 8.7E-26 T 10-11-2016 A4G23_RS10480 6c392a8e5267c7be8f560cc102317d14 178 Pfam PF09056 Prokaryotic phospholipase A2 70 178 1.4E-27 T 10-11-2016 IPR015141 Phospholipase A2, prokaryotic/fungal A4G23_RS10480 6c392a8e5267c7be8f560cc102317d14 178 SUPERFAMILY SSF48619 66 178 5.23E-21 T 10-11-2016 IPR016090 Phospholipase A2 domain KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417 A4G23_RS10480 6c392a8e5267c7be8f560cc102317d14 178 Gene3D G3DSA:1.20.90.10 69 178 3.7E-28 T 10-11-2016 IPR016090 Phospholipase A2 domain KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417 A4G23_RS15850 ca5362b76fe9646e8f2368b16bfd6a5e 368 Pfam PF01578 Cytochrome C assembly protein 147 363 2.5E-42 T 10-11-2016 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 A4G23_RS15850 ca5362b76fe9646e8f2368b16bfd6a5e 368 TIGRFAM TIGR03144 cytochr_II_ccsB: cytochrome c-type biogenesis protein CcsB 124 366 6.3E-74 T 10-11-2016 IPR017562 Cytochrome c-type biogenesis protein CcsA GO:0017004 A4G23_RS08240 8e58191d0faa95c4be6775207e157d5d 165 Pfam PF03703 Bacterial PH domain 87 159 1.8E-13 T 10-11-2016 IPR005182 Domain of unknown function DUF304 A4G23_RS05390 142d5f9fbae843b0373503f689293ba9 256 Pfam PF09339 IclR helix-turn-helix domain 13 63 4.1E-12 T 10-11-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4G23_RS05390 142d5f9fbae843b0373503f689293ba9 256 SUPERFAMILY SSF46785 11 83 7.27E-13 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS05390 142d5f9fbae843b0373503f689293ba9 256 Pfam PF01614 Bacterial transcriptional regulator 132 246 1.5E-27 T 10-11-2016 IPR014757 Transcription regulator IclR, C-terminal A4G23_RS05390 142d5f9fbae843b0373503f689293ba9 256 Gene3D G3DSA:3.30.450.40 86 250 2.0E-49 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS05390 142d5f9fbae843b0373503f689293ba9 256 Gene3D G3DSA:1.10.10.10 10 74 1.8E-16 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS05390 142d5f9fbae843b0373503f689293ba9 256 SUPERFAMILY SSF55781 78 250 3.4E-43 T 10-11-2016 IPR029016 GAF domain-like A4G23_RS05390 142d5f9fbae843b0373503f689293ba9 256 SMART SM00346 11 101 1.6E-15 T 10-11-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4G23_RS16240 eaf1c7c0665f6e44b6e23abc2b3b3410 131 PIRSF PIRSF028777 1 130 1.7E-53 T 10-11-2016 IPR031308 Uncharacterised conserved protein UCP028777 A4G23_RS16240 eaf1c7c0665f6e44b6e23abc2b3b3410 131 Pfam PF03733 Inner membrane component domain 68 118 7.0E-17 T 10-11-2016 IPR005185 Inner membrane component domain A4G23_RS16240 eaf1c7c0665f6e44b6e23abc2b3b3410 131 Pfam PF03733 Inner membrane component domain 4 54 7.8E-19 T 10-11-2016 IPR005185 Inner membrane component domain A4G23_RS10095 7105ca9cd456d389536b802271fb5dab 385 SUPERFAMILY SSF51556 283 367 1.25E-102 T 10-11-2016 IPR032466 Metal-dependent hydrolase A4G23_RS10095 7105ca9cd456d389536b802271fb5dab 385 SUPERFAMILY SSF51556 3 243 1.25E-102 T 10-11-2016 IPR032466 Metal-dependent hydrolase A4G23_RS10095 7105ca9cd456d389536b802271fb5dab 385 Gene3D G3DSA:3.20.20.140 1 374 2.7E-144 T 10-11-2016 A4G23_RS10095 7105ca9cd456d389536b802271fb5dab 385 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 2 360 1.2E-116 T 10-11-2016 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 A4G23_RS25000 8c8fb7691fefb376c21cdc498b57495d 117 Pfam PF03334 Na+/H+ antiporter subunit 12 90 1.7E-16 T 10-11-2016 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:0015992 A4G23_RS21125 83dc735fa2a72748b33aa8c0d403e04e 290 Pfam PF12833 Helix-turn-helix domain 199 276 2.4E-19 T 10-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4G23_RS21125 83dc735fa2a72748b33aa8c0d403e04e 290 SUPERFAMILY SSF51215 34 159 5.23E-18 T 10-11-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 A4G23_RS21125 83dc735fa2a72748b33aa8c0d403e04e 290 SUPERFAMILY SSF46689 180 227 6.0E-8 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS21125 83dc735fa2a72748b33aa8c0d403e04e 290 Gene3D G3DSA:1.10.10.60 233 278 1.1E-8 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS21125 83dc735fa2a72748b33aa8c0d403e04e 290 SUPERFAMILY SSF46689 231 278 9.32E-8 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS21125 83dc735fa2a72748b33aa8c0d403e04e 290 SMART SM00342 193 275 5.9E-26 T 10-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4G23_RS21125 83dc735fa2a72748b33aa8c0d403e04e 290 Pfam PF02311 AraC-like ligand binding domain 23 152 3.4E-23 T 10-11-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 A4G23_RS21125 83dc735fa2a72748b33aa8c0d403e04e 290 Gene3D G3DSA:2.60.120.280 34 160 8.2E-14 T 10-11-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 A4G23_RS21125 83dc735fa2a72748b33aa8c0d403e04e 290 Gene3D G3DSA:1.10.10.60 177 232 4.8E-15 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS21070 1659b5282f35e1a919bccf4cc8fa1484 227 Pfam PF00072 Response regulator receiver domain 7 119 1.5E-24 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS21070 1659b5282f35e1a919bccf4cc8fa1484 227 SMART SM00448 5 119 7.4E-31 T 10-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4G23_RS21070 1659b5282f35e1a919bccf4cc8fa1484 227 Gene3D G3DSA:3.40.50.2300 3 126 9.0E-36 T 10-11-2016 A4G23_RS21070 1659b5282f35e1a919bccf4cc8fa1484 227 SUPERFAMILY SSF52172 3 145 2.42E-37 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS03445 63af4c685a3df086eb6afc4ef0b88c0d 135 SUPERFAMILY SSF52091 9 118 4.71E-18 T 10-11-2016 IPR002645 STAS domain A4G23_RS03445 63af4c685a3df086eb6afc4ef0b88c0d 135 Gene3D G3DSA:3.30.750.24 12 101 3.1E-14 T 10-11-2016 IPR002645 STAS domain A4G23_RS03445 63af4c685a3df086eb6afc4ef0b88c0d 135 Pfam PF01740 STAS domain 19 100 8.3E-8 T 10-11-2016 IPR002645 STAS domain A4G23_RS11225 1c3adc0718b394fd4be1a4981fa38c2e 454 Pfam PF00999 Sodium/hydrogen exchanger family 25 416 3.7E-44 T 10-11-2016 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A4G23_RS04550 1745987db7acc86e9f21cf1faf4cbc57 340 Pfam PF01636 Phosphotransferase enzyme family 32 276 1.0E-48 T 10-11-2016 IPR002575 Aminoglycoside phosphotransferase A4G23_RS04550 1745987db7acc86e9f21cf1faf4cbc57 340 Gene3D G3DSA:3.90.1200.10 110 295 3.8E-34 T 10-11-2016 A4G23_RS04550 1745987db7acc86e9f21cf1faf4cbc57 340 SUPERFAMILY SSF56112 7 313 8.16E-59 T 10-11-2016 IPR011009 Protein kinase-like domain A4G23_RS21010 ed5e4a3fa5b6acfd386697bbd4e2adf2 150 SUPERFAMILY SSF48452 102 148 2.52E-5 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS21010 ed5e4a3fa5b6acfd386697bbd4e2adf2 150 Gene3D G3DSA:1.25.40.10 107 147 1.3E-5 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS24155 9e05318cb6ef25a3bb39bd51c982c586 474 Gene3D G3DSA:3.90.1300.10 7 465 3.1E-122 T 10-11-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4G23_RS24155 9e05318cb6ef25a3bb39bd51c982c586 474 SUPERFAMILY SSF75304 8 459 1.57E-117 T 10-11-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4G23_RS24155 9e05318cb6ef25a3bb39bd51c982c586 474 ProSitePatterns PS00571 Amidases signature. 154 185 - T 10-11-2016 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 A4G23_RS24155 9e05318cb6ef25a3bb39bd51c982c586 474 Pfam PF01425 Amidase 29 448 5.7E-108 T 10-11-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4G23_RS06245 9d040a301e3d52829d051de6821c9aeb 450 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 56 412 1.0E-114 T 10-11-2016 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 A4G23_RS06245 9d040a301e3d52829d051de6821c9aeb 450 Pfam PF01098 Cell cycle protein 58 411 1.6E-94 T 10-11-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 A4G23_RS06245 9d040a301e3d52829d051de6821c9aeb 450 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 371 395 - T 10-11-2016 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 A4G23_RS02395 7e8fc3e4f5cb763f432f2e20809b135f 463 SUPERFAMILY SSF51735 54 221 1.92E-39 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS02395 7e8fc3e4f5cb763f432f2e20809b135f 463 Gene3D G3DSA:3.40.50.720 61 244 1.1E-43 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS02395 7e8fc3e4f5cb763f432f2e20809b135f 463 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 62 187 2.4E-15 T 10-11-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 A4G23_RS14390 03c7502b8889ff00dcd608d11f42a1c3 191 Pfam PF00692 dUTPase 70 180 2.6E-10 T 10-11-2016 IPR008180 Deoxyuridine triphosphate nucleotidohydrolase/Deoxycytidine triphosphate deaminase GO:0016787|GO:0046080 A4G23_RS14390 03c7502b8889ff00dcd608d11f42a1c3 191 Gene3D G3DSA:2.70.40.10 2 184 2.1E-67 T 10-11-2016 IPR029054 dUTPase-like A4G23_RS14390 03c7502b8889ff00dcd608d11f42a1c3 191 Hamap MF_00146 Deoxycytidine triphosphate deaminase [dcd]. 1 182 34.327 T 10-11-2016 IPR011962 Deoxycytidine triphosphate deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 A4G23_RS14390 03c7502b8889ff00dcd608d11f42a1c3 191 SUPERFAMILY SSF51283 2 184 2.36E-57 T 10-11-2016 IPR029054 dUTPase-like A4G23_RS14390 03c7502b8889ff00dcd608d11f42a1c3 191 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 3 181 6.1E-65 T 10-11-2016 IPR011962 Deoxycytidine triphosphate deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 A4G23_RS05405 e8d09582ccebaff75dd9495eec2fe9ce 429 Pfam PF07730 Histidine kinase 190 257 2.3E-15 T 10-11-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4G23_RS03455 c28fa36a31dd5d9bc4abc3db0035f3f0 407 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 241 361 3.8E-4 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS03455 c28fa36a31dd5d9bc4abc3db0035f3f0 407 SUPERFAMILY SSF81606 241 400 1.57E-8 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS22865 673247f84e402a6a037e0bd6c34ca3d8 281 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 275 4.5E-21 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS22865 673247f84e402a6a037e0bd6c34ca3d8 281 Gene3D G3DSA:1.10.3720.10 8 269 5.4E-65 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS22865 673247f84e402a6a037e0bd6c34ca3d8 281 SUPERFAMILY SSF161098 9 281 2.24E-70 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS06555 2672229e7c1e0ba865705b3e7619ec91 133 SUPERFAMILY SSF52172 3 129 3.56E-9 T 10-11-2016 IPR011006 CheY-like superfamily A4G23_RS06555 2672229e7c1e0ba865705b3e7619ec91 133 Gene3D G3DSA:3.40.50.2300 2 128 1.2E-11 T 10-11-2016 A4G23_RS01765 42250069db2d32b55ecbffa3e78a2114 287 SUPERFAMILY SSF141673 12 142 2.09E-30 T 10-11-2016 A4G23_RS01765 42250069db2d32b55ecbffa3e78a2114 287 SUPERFAMILY SSF50800 10 58 1.36E-19 T 10-11-2016 IPR011037 Pyruvate kinase-like, insert domain A4G23_RS01765 42250069db2d32b55ecbffa3e78a2114 287 SUPERFAMILY SSF50800 161 281 1.36E-19 T 10-11-2016 IPR011037 Pyruvate kinase-like, insert domain A4G23_RS01765 42250069db2d32b55ecbffa3e78a2114 287 Pfam PF03476 MOSC N-terminal beta barrel domain 12 125 2.9E-24 T 10-11-2016 IPR005303 MOSC, N-terminal beta barrel A4G23_RS01765 42250069db2d32b55ecbffa3e78a2114 287 Pfam PF03473 MOSC domain 152 279 2.5E-33 T 10-11-2016 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 A4G23_RS12795 479184c0d59d59a1d1e25c5da15d9a29 520 Pfam PF00149 Calcineurin-like phosphoesterase 230 397 1.9E-13 T 10-11-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 A4G23_RS12795 479184c0d59d59a1d1e25c5da15d9a29 520 SUPERFAMILY SSF56300 226 418 1.44E-28 T 10-11-2016 IPR029052 Metallo-dependent phosphatase-like A4G23_RS12795 479184c0d59d59a1d1e25c5da15d9a29 520 Gene3D G3DSA:3.60.21.10 228 398 4.0E-19 T 10-11-2016 IPR029052 Metallo-dependent phosphatase-like A4G23_RS23355 6f7352c358efa02a521da0a466dbba50 227 SUPERFAMILY SSF51366 7 219 8.95E-36 T 10-11-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 A4G23_RS23355 6f7352c358efa02a521da0a466dbba50 227 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 12 222 24.933 T 10-11-2016 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 A4G23_RS23355 6f7352c358efa02a521da0a466dbba50 227 Gene3D G3DSA:3.20.20.70 7 221 1.3E-42 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS23355 6f7352c358efa02a521da0a466dbba50 227 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 12 217 1.4E-23 T 10-11-2016 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 A4G23_RS26705 ef1555444b2863e58c9f209abfc2e27e 139 Gene3D G3DSA:2.30.30.240 25 86 1.4E-17 T 10-11-2016 A4G23_RS26705 ef1555444b2863e58c9f209abfc2e27e 139 Pfam PF05239 PRC-barrel domain 25 94 1.6E-18 T 10-11-2016 IPR027275 PRC-barrel domain A4G23_RS26705 ef1555444b2863e58c9f209abfc2e27e 139 SUPERFAMILY SSF50346 24 127 1.24E-24 T 10-11-2016 IPR011033 PRC-barrel-like A4G23_RS06190 b643692aaf2f78c55f954a79f4181157 186 TIGRFAM TIGR00077 lspA: signal peptidase II 33 174 8.4E-25 T 10-11-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 A4G23_RS06190 b643692aaf2f78c55f954a79f4181157 186 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 28 180 14.636 T 10-11-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 A4G23_RS06190 b643692aaf2f78c55f954a79f4181157 186 ProSitePatterns PS00855 Signal peptidases II signature. 120 132 - T 10-11-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 A4G23_RS06190 b643692aaf2f78c55f954a79f4181157 186 Pfam PF01252 Signal peptidase (SPase) II 37 174 1.1E-28 T 10-11-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 A4G23_RS06190 b643692aaf2f78c55f954a79f4181157 186 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 155 171 2.8E-15 T 10-11-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 A4G23_RS06190 b643692aaf2f78c55f954a79f4181157 186 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 117 132 2.8E-15 T 10-11-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 A4G23_RS06190 b643692aaf2f78c55f954a79f4181157 186 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 75 83 2.8E-15 T 10-11-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 A4G23_RS06120 1ae2920a6327737f75471fc3d0f23f85 449 SUPERFAMILY SSF56112 48 205 4.08E-8 T 10-11-2016 IPR011009 Protein kinase-like domain A4G23_RS06120 1ae2920a6327737f75471fc3d0f23f85 449 Gene3D G3DSA:3.90.1200.10 84 243 7.0E-9 T 10-11-2016 A4G23_RS06120 1ae2920a6327737f75471fc3d0f23f85 449 Gene3D G3DSA:3.90.1200.10 25 38 7.0E-9 T 10-11-2016 A4G23_RS06120 1ae2920a6327737f75471fc3d0f23f85 449 Pfam PF10009 Uncharacterized protein conserved in bacteria (DUF2252) 37 438 2.2E-118 T 10-11-2016 IPR018721 Protein of unknown function DUF2252 A4G23_RS07440 f535c7f49b0b65756bb7a9f7f0f6a2a5 404 Pfam PF06259 Alpha/beta hydrolase 159 332 2.5E-55 T 10-11-2016 IPR010427 Protein of unknown function DUF1023 A4G23_RS07440 f535c7f49b0b65756bb7a9f7f0f6a2a5 404 Gene3D G3DSA:3.40.50.1820 222 318 1.5E-6 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS07440 f535c7f49b0b65756bb7a9f7f0f6a2a5 404 SUPERFAMILY SSF53474 253 333 5.93E-8 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS13165 a3ce748e6717f746a462740e827b461d 398 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 46 384 3.4E-138 T 10-11-2016 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 A4G23_RS13165 a3ce748e6717f746a462740e827b461d 398 SUPERFAMILY SSF52518 44 388 4.24E-100 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS13165 a3ce748e6717f746a462740e827b461d 398 Gene3D G3DSA:3.40.50.970 35 384 3.7E-133 T 10-11-2016 IPR029061 Thiamin diphosphate-binding fold A4G23_RS13165 a3ce748e6717f746a462740e827b461d 398 Pfam PF00676 Dehydrogenase E1 component 76 346 3.0E-77 T 10-11-2016 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 A4G23_RS04165 0a54eb45a8fd8d8c919ef76fa76688b2 454 SUPERFAMILY SSF53720 5 450 1.57E-154 T 10-11-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A4G23_RS04165 0a54eb45a8fd8d8c919ef76fa76688b2 454 Pfam PF00171 Aldehyde dehydrogenase family 4 448 6.6E-161 T 10-11-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A4G23_RS04165 0a54eb45a8fd8d8c919ef76fa76688b2 454 Gene3D G3DSA:3.40.605.10 5 242 4.5E-88 T 10-11-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A4G23_RS04165 0a54eb45a8fd8d8c919ef76fa76688b2 454 Gene3D G3DSA:3.40.309.10 243 428 1.8E-60 T 10-11-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 A4G23_RS04165 0a54eb45a8fd8d8c919ef76fa76688b2 454 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 257 268 - T 10-11-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 A4G23_RS04165 0a54eb45a8fd8d8c919ef76fa76688b2 454 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 229 236 - T 10-11-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 A4G23_RS22105 02da0429ad39f0aea3bf2437bd7362ad 523 SUPERFAMILY SSF103473 471 496 1.15E-55 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS22105 02da0429ad39f0aea3bf2437bd7362ad 523 SUPERFAMILY SSF103473 252 423 1.15E-55 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS22105 02da0429ad39f0aea3bf2437bd7362ad 523 SUPERFAMILY SSF103473 7 202 1.15E-55 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS22105 02da0429ad39f0aea3bf2437bd7362ad 523 Gene3D G3DSA:1.20.1250.20 14 200 9.0E-26 T 10-11-2016 A4G23_RS22105 02da0429ad39f0aea3bf2437bd7362ad 523 Pfam PF07690 Major Facilitator Superfamily 26 413 1.9E-39 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS22105 02da0429ad39f0aea3bf2437bd7362ad 523 Gene3D G3DSA:1.20.1250.20 267 424 5.0E-13 T 10-11-2016 A4G23_RS22105 02da0429ad39f0aea3bf2437bd7362ad 523 Gene3D G3DSA:1.20.1250.20 472 498 5.0E-13 T 10-11-2016 A4G23_RS15320 f309ce851b2fa26b9c0dc5d9b45bb254 217 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 42 215 2.3E-16 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS15320 f309ce851b2fa26b9c0dc5d9b45bb254 217 Gene3D G3DSA:1.10.3720.10 18 201 2.0E-24 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS15320 f309ce851b2fa26b9c0dc5d9b45bb254 217 SUPERFAMILY SSF161098 22 204 2.22E-31 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS22655 53f22d2799f5cf59669ea0886f46f5a1 132 Pfam PF04472 Protein of unknown function (DUF552) 51 121 8.5E-20 T 10-11-2016 IPR007561 Cell division protein SepF/SepF-related GO:0090529 A4G23_RS22655 53f22d2799f5cf59669ea0886f46f5a1 132 Hamap MF_01197 Cell division protein SepF [sepF]. 14 129 14.411 T 10-11-2016 IPR023052 Cell division protein SepF GO:0090529 A4G23_RS11330 9877a256296e075efe65c74d031d63bf 167 SUPERFAMILY SSF109854 2 162 3.36E-39 T 10-11-2016 A4G23_RS11330 9877a256296e075efe65c74d031d63bf 167 Pfam PF04978 Protein of unknown function (DUF664) 16 163 6.8E-40 T 10-11-2016 IPR007061 Protein of unknown function DUF664 A4G23_RS11330 9877a256296e075efe65c74d031d63bf 167 Gene3D G3DSA:1.20.120.450 2 166 8.1E-40 T 10-11-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase A4G23_RS00145 0751633409f94e25b87d114c8f3502a6 303 Gene3D G3DSA:3.40.50.720 3 295 3.2E-40 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS00145 0751633409f94e25b87d114c8f3502a6 303 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 210 3.4E-23 T 10-11-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 A4G23_RS00145 0751633409f94e25b87d114c8f3502a6 303 SUPERFAMILY SSF51735 1 245 5.79E-46 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS00145 0751633409f94e25b87d114c8f3502a6 303 SUPERFAMILY SSF51735 274 298 5.79E-46 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS15180 31260e104452dd842eecadf768a1488e 54 Pfam PF00471 Ribosomal protein L33 9 54 8.1E-16 T 10-11-2016 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS15180 31260e104452dd842eecadf768a1488e 54 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 54 2.1E-22 T 10-11-2016 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS15180 31260e104452dd842eecadf768a1488e 54 ProSitePatterns PS00582 Ribosomal protein L33 signature. 22 41 - T 10-11-2016 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS15180 31260e104452dd842eecadf768a1488e 54 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 2 54 14.212 T 10-11-2016 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4G23_RS15180 31260e104452dd842eecadf768a1488e 54 SUPERFAMILY SSF57829 4 54 4.94E-17 T 10-11-2016 IPR011332 Zinc-binding ribosomal protein GO:0006412 A4G23_RS05165 dc86dd905fec2f628aeb309bfbd6becf 91 Pfam PF04226 Transglycosylase associated protein 33 80 5.6E-9 T 10-11-2016 IPR007341 Transglycosylase-associated protein GO:0016021 A4G23_RS12455 cd750b7623e43e65f9b10ececad80571 269 SUPERFAMILY SSF53474 3 262 1.92E-33 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS12455 cd750b7623e43e65f9b10ececad80571 269 Gene3D G3DSA:3.40.50.1820 197 262 1.6E-39 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS12455 cd750b7623e43e65f9b10ececad80571 269 Gene3D G3DSA:3.40.50.1820 3 154 1.6E-39 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS12455 cd750b7623e43e65f9b10ececad80571 269 Pfam PF12697 Alpha/beta hydrolase family 25 245 5.1E-10 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS15345 5f856c2e4526ddd5d6c946adfc880c73 240 SUPERFAMILY SSF53335 21 233 1.51E-17 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS15345 5f856c2e4526ddd5d6c946adfc880c73 240 Pfam PF02636 Putative S-adenosyl-L-methionine-dependent methyltransferase 22 172 7.9E-9 T 10-11-2016 IPR003788 Putative S-adenosyl-L-methionine-dependent methyltransferase MidA Reactome: R-HSA-6799198 A4G23_RS12885 6f73521bff0c23d386d9b00680356a86 277 Pfam PF03724 META domain 160 269 2.5E-22 T 10-11-2016 IPR005184 Domain of unknown function DUF306, Meta/HslJ A4G23_RS12885 6f73521bff0c23d386d9b00680356a86 277 Pfam PF03724 META domain 42 152 5.4E-23 T 10-11-2016 IPR005184 Domain of unknown function DUF306, Meta/HslJ A4G23_RS20000 54e9887275f6eb880a090fd152179eab 387 SUPERFAMILY SSF52540 4 255 1.12E-71 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS20000 54e9887275f6eb880a090fd152179eab 387 Pfam PF00005 ABC transporter 32 183 8.2E-32 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS20000 54e9887275f6eb880a090fd152179eab 387 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 302 1.6E-16 T 10-11-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A4G23_RS20000 54e9887275f6eb880a090fd152179eab 387 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS20000 54e9887275f6eb880a090fd152179eab 387 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 234 322 8.0E-28 T 10-11-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A4G23_RS20000 54e9887275f6eb880a090fd152179eab 387 SMART SM00382 40 233 2.1E-17 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS20000 54e9887275f6eb880a090fd152179eab 387 Gene3D G3DSA:3.40.50.300 2 257 2.6E-81 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS05650 4d3e6471f6ebbd0fbc48af3ee107481b 166 Pfam PF03703 Bacterial PH domain 77 154 2.1E-16 T 10-11-2016 IPR005182 Domain of unknown function DUF304 A4G23_RS02195 5764fc4ee8287b2494d6aef49887f0aa 237 SMART SM01007 11 202 1.8E-49 T 10-11-2016 IPR001303 Class II aldolase/adducin N-terminal A4G23_RS02195 5764fc4ee8287b2494d6aef49887f0aa 237 Gene3D G3DSA:3.40.225.10 7 232 7.8E-60 T 10-11-2016 IPR001303 Class II aldolase/adducin N-terminal A4G23_RS02195 5764fc4ee8287b2494d6aef49887f0aa 237 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 12 202 3.2E-38 T 10-11-2016 IPR001303 Class II aldolase/adducin N-terminal A4G23_RS02195 5764fc4ee8287b2494d6aef49887f0aa 237 SUPERFAMILY SSF53639 7 216 6.87E-55 T 10-11-2016 IPR001303 Class II aldolase/adducin N-terminal A4G23_RS10150 6db66fdb562b1ca7a51fd740a22aa3d2 677 SUPERFAMILY SSF52540 352 513 3.81E-12 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS10150 6db66fdb562b1ca7a51fd740a22aa3d2 677 Pfam PF02706 Chain length determinant protein 24 151 3.7E-7 T 10-11-2016 IPR003856 Lipopolysaccharide biosynthesis GO:0009103|GO:0016020 A4G23_RS10150 6db66fdb562b1ca7a51fd740a22aa3d2 677 Gene3D G3DSA:3.40.50.300 352 525 8.6E-13 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS13365 727e509c758ae4b0f5adc63ad1c2aa58 212 SUPERFAMILY SSF52317 4 191 2.52E-58 T 10-11-2016 IPR029062 Class I glutamine amidotransferase-like A4G23_RS13365 727e509c758ae4b0f5adc63ad1c2aa58 212 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 5 190 6.1E-62 T 10-11-2016 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A4G23_RS13365 727e509c758ae4b0f5adc63ad1c2aa58 212 PRINTS PR00097 Anthranilate synthase component II signature 122 134 3.0E-34 T 10-11-2016 A4G23_RS13365 727e509c758ae4b0f5adc63ad1c2aa58 212 PRINTS PR00097 Anthranilate synthase component II signature 167 180 3.0E-34 T 10-11-2016 A4G23_RS13365 727e509c758ae4b0f5adc63ad1c2aa58 212 PRINTS PR00097 Anthranilate synthase component II signature 5 19 3.0E-34 T 10-11-2016 A4G23_RS13365 727e509c758ae4b0f5adc63ad1c2aa58 212 PRINTS PR00097 Anthranilate synthase component II signature 102 110 3.0E-34 T 10-11-2016 A4G23_RS13365 727e509c758ae4b0f5adc63ad1c2aa58 212 PRINTS PR00097 Anthranilate synthase component II signature 77 88 3.0E-34 T 10-11-2016 A4G23_RS13365 727e509c758ae4b0f5adc63ad1c2aa58 212 PRINTS PR00097 Anthranilate synthase component II signature 49 58 3.0E-34 T 10-11-2016 A4G23_RS13365 727e509c758ae4b0f5adc63ad1c2aa58 212 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 46 60 3.1E-9 T 10-11-2016 A4G23_RS13365 727e509c758ae4b0f5adc63ad1c2aa58 212 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 77 93 3.1E-9 T 10-11-2016 A4G23_RS13365 727e509c758ae4b0f5adc63ad1c2aa58 212 Pfam PF00117 Glutamine amidotransferase class-I 7 188 4.0E-52 T 10-11-2016 IPR017926 Glutamine amidotransferase A4G23_RS13365 727e509c758ae4b0f5adc63ad1c2aa58 212 PRINTS PR00096 Glutamine amidotransferase superfamily signature 49 58 1.3E-13 T 10-11-2016 A4G23_RS13365 727e509c758ae4b0f5adc63ad1c2aa58 212 PRINTS PR00096 Glutamine amidotransferase superfamily signature 77 88 1.3E-13 T 10-11-2016 A4G23_RS13365 727e509c758ae4b0f5adc63ad1c2aa58 212 PRINTS PR00096 Glutamine amidotransferase superfamily signature 167 180 1.3E-13 T 10-11-2016 A4G23_RS13365 727e509c758ae4b0f5adc63ad1c2aa58 212 Gene3D G3DSA:3.40.50.880 4 191 3.5E-67 T 10-11-2016 IPR029062 Class I glutamine amidotransferase-like A4G23_RS25465 b5610cc32cd4a4dd93bfc109d3504311 189 Pfam PF01202 Shikimate kinase 15 134 1.5E-10 T 10-11-2016 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 A4G23_RS25465 b5610cc32cd4a4dd93bfc109d3504311 189 TIGRFAM TIGR01313 therm_gnt_kin: carbohydrate kinase, thermoresistant glucokinase family 9 165 1.1E-50 T 10-11-2016 IPR006001 Carbohydrate kinase, thermoresistant glucokinase GO:0005975|GO:0016301 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530 A4G23_RS25465 b5610cc32cd4a4dd93bfc109d3504311 189 Gene3D G3DSA:3.40.50.300 6 170 6.8E-62 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS25465 b5610cc32cd4a4dd93bfc109d3504311 189 SUPERFAMILY SSF52540 6 169 3.89E-26 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS02650 39d709e6fbcd6d31cce272ca219c5dfa 261 SUPERFAMILY SSF100920 81 189 3.53E-9 T 10-11-2016 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 A4G23_RS02650 39d709e6fbcd6d31cce272ca219c5dfa 261 SUPERFAMILY SSF53067 2 69 1.22E-11 T 10-11-2016 A4G23_RS02650 39d709e6fbcd6d31cce272ca219c5dfa 261 Gene3D G3DSA:3.30.420.40 3 44 1.4E-6 T 10-11-2016 A4G23_RS02650 39d709e6fbcd6d31cce272ca219c5dfa 261 PRINTS PR00301 70kDa heat shock protein signature 18 34 2.1E-5 T 10-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4G23_RS02650 39d709e6fbcd6d31cce272ca219c5dfa 261 PRINTS PR00301 70kDa heat shock protein signature 52 72 2.1E-5 T 10-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4G23_RS02650 39d709e6fbcd6d31cce272ca219c5dfa 261 Pfam PF00012 Hsp70 protein 1 188 4.1E-16 T 10-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4G23_RS02650 39d709e6fbcd6d31cce272ca219c5dfa 261 Gene3D G3DSA:2.60.34.10 58 189 4.9E-13 T 10-11-2016 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 A4G23_RS09985 f697e9bdadd4fbe651088079b097182d 209 Pfam PF05995 Cysteine dioxygenase type I 15 104 6.6E-17 T 10-11-2016 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 A4G23_RS09985 f697e9bdadd4fbe651088079b097182d 209 Gene3D G3DSA:2.60.120.10 46 199 1.4E-17 T 10-11-2016 IPR014710 RmlC-like jelly roll fold A4G23_RS09985 f697e9bdadd4fbe651088079b097182d 209 SUPERFAMILY SSF51182 155 191 6.43E-27 T 10-11-2016 IPR011051 RmlC-like cupin domain A4G23_RS09985 f697e9bdadd4fbe651088079b097182d 209 SUPERFAMILY SSF51182 17 116 6.43E-27 T 10-11-2016 IPR011051 RmlC-like cupin domain A4G23_RS06855 c316bc5dd96913aa36a2a4e86f4fb849 300 Gene3D G3DSA:1.10.3720.10 25 287 1.8E-67 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS06855 c316bc5dd96913aa36a2a4e86f4fb849 300 SUPERFAMILY SSF161098 29 300 2.99E-69 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS06855 c316bc5dd96913aa36a2a4e86f4fb849 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 293 4.2E-18 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS22365 51dacca77f4d84bad8f5d9090a684342 447 SUPERFAMILY SSF53187 314 424 2.29E-64 T 10-11-2016 A4G23_RS22365 51dacca77f4d84bad8f5d9090a684342 447 SUPERFAMILY SSF53187 16 211 2.29E-64 T 10-11-2016 A4G23_RS22365 51dacca77f4d84bad8f5d9090a684342 447 Gene3D G3DSA:3.40.630.10 15 190 4.0E-72 T 10-11-2016 A4G23_RS22365 51dacca77f4d84bad8f5d9090a684342 447 Gene3D G3DSA:3.40.630.10 311 424 4.0E-72 T 10-11-2016 A4G23_RS22365 51dacca77f4d84bad8f5d9090a684342 447 Gene3D G3DSA:3.30.70.360 198 300 5.4E-31 T 10-11-2016 IPR011650 Peptidase M20, dimerisation domain A4G23_RS22365 51dacca77f4d84bad8f5d9090a684342 447 Pfam PF07687 Peptidase dimerisation domain 202 294 7.4E-13 T 10-11-2016 IPR011650 Peptidase M20, dimerisation domain A4G23_RS22365 51dacca77f4d84bad8f5d9090a684342 447 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 33 352 7.1E-72 T 10-11-2016 IPR017439 Amidohydrolase GO:0016787 A4G23_RS22365 51dacca77f4d84bad8f5d9090a684342 447 Pfam PF01546 Peptidase family M20/M25/M40 85 355 6.6E-20 T 10-11-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A4G23_RS22365 51dacca77f4d84bad8f5d9090a684342 447 SUPERFAMILY SSF55031 200 304 3.93E-27 T 10-11-2016 IPR011650 Peptidase M20, dimerisation domain A4G23_RS14720 331a212c4cd020d1060bee68db0b5eb0 113 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 6 95 1.6E-23 T 10-11-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family A4G23_RS14720 331a212c4cd020d1060bee68db0b5eb0 113 PIRSF PIRSF004555 6 113 1.9E-33 T 10-11-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family A4G23_RS14720 331a212c4cd020d1060bee68db0b5eb0 113 Gene3D G3DSA:3.30.1310.10 5 113 2.2E-40 T 10-11-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family A4G23_RS14720 331a212c4cd020d1060bee68db0b5eb0 113 SUPERFAMILY SSF82607 14 108 3.66E-27 T 10-11-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family A4G23_RS14720 331a212c4cd020d1060bee68db0b5eb0 113 Pfam PF02575 YbaB/EbfC DNA-binding family 15 103 2.2E-31 T 10-11-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family A4G23_RS14720 331a212c4cd020d1060bee68db0b5eb0 113 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 8 102 21.307 T 10-11-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family A4G23_RS15955 d323f3c7c3f38a1b4f270043ef2a070c 127 Pfam PF05973 Phage derived protein Gp49-like (DUF891) 18 85 1.1E-9 T 10-11-2016 IPR009241 Toxin HigB-like A4G23_RS26155 f1a18917d1c636e3e8825a13d7f88c6b 241 SUPERFAMILY SSF52540 2 212 2.34E-49 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS26155 f1a18917d1c636e3e8825a13d7f88c6b 241 SMART SM00382 27 217 2.3E-10 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS26155 f1a18917d1c636e3e8825a13d7f88c6b 241 Gene3D G3DSA:3.40.50.300 1 211 4.6E-56 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS26155 f1a18917d1c636e3e8825a13d7f88c6b 241 Pfam PF00005 ABC transporter 19 168 9.6E-28 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS24770 120fa4f0b54965dbaae223fcd3d969ac 337 TIGRFAM TIGR03395 sphingomy: sphingomyelin phosphodiesterase 49 334 7.2E-93 T 10-11-2016 IPR017766 Sphingomyelinase C/phospholipase C GO:0005576|GO:0008081 A4G23_RS24770 120fa4f0b54965dbaae223fcd3d969ac 337 Gene3D G3DSA:3.60.10.10 41 333 3.0E-11 T 10-11-2016 IPR005135 Endonuclease/exonuclease/phosphatase A4G23_RS24770 120fa4f0b54965dbaae223fcd3d969ac 337 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 52 329 2.4E-24 T 10-11-2016 IPR005135 Endonuclease/exonuclease/phosphatase A4G23_RS24770 120fa4f0b54965dbaae223fcd3d969ac 337 SUPERFAMILY SSF56219 47 334 2.88E-74 T 10-11-2016 IPR005135 Endonuclease/exonuclease/phosphatase A4G23_RS08930 9916d317eaffd2f746fa4c742d773ec1 385 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 342 361 - T 10-11-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A4G23_RS08930 9916d317eaffd2f746fa4c742d773ec1 385 Gene3D G3DSA:2.40.110.10 122 223 1.6E-37 T 10-11-2016 A4G23_RS08930 9916d317eaffd2f746fa4c742d773ec1 385 SUPERFAMILY SSF56645 4 246 1.31E-78 T 10-11-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 A4G23_RS08930 9916d317eaffd2f746fa4c742d773ec1 385 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 223 1.9E-25 T 10-11-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 A4G23_RS08930 9916d317eaffd2f746fa4c742d773ec1 385 SUPERFAMILY SSF47203 233 383 1.55E-48 T 10-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4G23_RS08930 9916d317eaffd2f746fa4c742d773ec1 385 Gene3D G3DSA:1.10.540.10 6 120 6.2E-33 T 10-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 A4G23_RS08930 9916d317eaffd2f746fa4c742d773ec1 385 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 235 383 5.5E-45 T 10-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A4G23_RS08930 9916d317eaffd2f746fa4c742d773ec1 385 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 119 2.2E-30 T 10-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 A4G23_RS08930 9916d317eaffd2f746fa4c742d773ec1 385 Gene3D G3DSA:1.20.140.10 224 383 7.7E-59 T 10-11-2016 A4G23_RS26450 acfbe158316dc003e5544dd5cfacb32a 243 SUPERFAMILY SSF49464 146 194 4.9E-5 T 10-11-2016 IPR008969 Carboxypeptidase-like, regulatory domain A4G23_RS05130 8f37ecd74600c55d8d40dff8e85aef10 136 Pfam PF13581 Histidine kinase-like ATPase domain 6 132 1.0E-14 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS05130 8f37ecd74600c55d8d40dff8e85aef10 136 Gene3D G3DSA:3.30.565.10 17 134 1.2E-5 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS05130 8f37ecd74600c55d8d40dff8e85aef10 136 SUPERFAMILY SSF55874 27 133 5.54E-8 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS12030 b4d262d84d143b4b893a50fff37a03f7 421 Pfam PF13416 Bacterial extracellular solute-binding protein 55 353 4.1E-32 T 10-11-2016 A4G23_RS12030 b4d262d84d143b4b893a50fff37a03f7 421 Gene3D G3DSA:3.40.190.10 48 163 1.6E-15 T 10-11-2016 A4G23_RS12030 b4d262d84d143b4b893a50fff37a03f7 421 Gene3D G3DSA:3.40.190.10 164 344 6.1E-31 T 10-11-2016 A4G23_RS12030 b4d262d84d143b4b893a50fff37a03f7 421 SUPERFAMILY SSF53850 31 413 3.06E-60 T 10-11-2016 A4G23_RS14130 fa07e2f8ccd5925dbfd50ec33e1b11af 121 Pfam PF08000 Bacterial PH domain 3 118 7.8E-47 T 10-11-2016 IPR012544 Bacterial Pleckstrin homology domain A4G23_RS14130 fa07e2f8ccd5925dbfd50ec33e1b11af 121 Gene3D G3DSA:2.30.29.50 3 100 5.9E-42 T 10-11-2016 IPR012544 Bacterial Pleckstrin homology domain A4G23_RS14130 fa07e2f8ccd5925dbfd50ec33e1b11af 121 SUPERFAMILY SSF50729 3 120 6.56E-44 T 10-11-2016 IPR011993 PH domain-like A4G23_RS21900 164a7acfc983d27235ec0754ba4984d5 278 PRINTS PR00412 Epoxide hydrolase signature 104 117 1.3E-8 T 10-11-2016 IPR000639 Epoxide hydrolase-like GO:0003824 A4G23_RS21900 164a7acfc983d27235ec0754ba4984d5 278 PRINTS PR00412 Epoxide hydrolase signature 27 45 1.3E-8 T 10-11-2016 IPR000639 Epoxide hydrolase-like GO:0003824 A4G23_RS21900 164a7acfc983d27235ec0754ba4984d5 278 PRINTS PR00412 Epoxide hydrolase signature 47 62 1.3E-8 T 10-11-2016 IPR000639 Epoxide hydrolase-like GO:0003824 A4G23_RS21900 164a7acfc983d27235ec0754ba4984d5 278 PRINTS PR00412 Epoxide hydrolase signature 248 270 1.3E-8 T 10-11-2016 IPR000639 Epoxide hydrolase-like GO:0003824 A4G23_RS21900 164a7acfc983d27235ec0754ba4984d5 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 47 62 6.9E-5 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS21900 164a7acfc983d27235ec0754ba4984d5 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 90 103 6.9E-5 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS21900 164a7acfc983d27235ec0754ba4984d5 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 6.9E-5 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS21900 164a7acfc983d27235ec0754ba4984d5 278 SUPERFAMILY SSF53474 3 272 2.68E-51 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS21900 164a7acfc983d27235ec0754ba4984d5 278 Pfam PF12697 Alpha/beta hydrolase family 23 265 3.6E-24 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS21900 164a7acfc983d27235ec0754ba4984d5 278 Gene3D G3DSA:3.40.50.1820 3 272 7.5E-54 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS15310 21d4c0f4936cbb812ee4b6a38b849462 370 Pfam PF00756 Putative esterase 131 294 5.2E-11 T 10-11-2016 IPR000801 Putative esterase Reactome: R-HSA-156590 A4G23_RS15310 21d4c0f4936cbb812ee4b6a38b849462 370 SUPERFAMILY SSF53474 107 367 6.78E-28 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS15310 21d4c0f4936cbb812ee4b6a38b849462 370 Gene3D G3DSA:3.40.50.1820 112 367 7.0E-39 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS11590 9ed987273f45f705ded791b3e74e14e8 261 Pfam PF01061 ABC-2 type transporter 4 217 6.9E-35 T 10-11-2016 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A4G23_RS11590 9ed987273f45f705ded791b3e74e14e8 261 PIRSF PIRSF006648 1 261 6.7E-68 T 10-11-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 A4G23_RS19125 3da3d3599a7fed8df64c1b6f8020d7a5 131 Gene3D G3DSA:1.20.120.400 15 130 2.3E-49 T 10-11-2016 IPR014123 Superoxide dismutase, Nickel-type GO:0004784|GO:0016151|GO:0016209 MetaCyc: PWY-6854 A4G23_RS19125 3da3d3599a7fed8df64c1b6f8020d7a5 131 TIGRFAM TIGR02753 sodN: superoxide dismutase, Ni 1 131 9.3E-57 T 10-11-2016 IPR014123 Superoxide dismutase, Nickel-type GO:0004784|GO:0016151|GO:0016209 MetaCyc: PWY-6854 A4G23_RS19125 3da3d3599a7fed8df64c1b6f8020d7a5 131 Pfam PF09055 Nickel-containing superoxide dismutase 11 129 5.3E-43 T 10-11-2016 IPR014123 Superoxide dismutase, Nickel-type GO:0004784|GO:0016151|GO:0016209 MetaCyc: PWY-6854 A4G23_RS19125 3da3d3599a7fed8df64c1b6f8020d7a5 131 SUPERFAMILY SSF109770 15 131 2.88E-53 T 10-11-2016 IPR014123 Superoxide dismutase, Nickel-type GO:0004784|GO:0016151|GO:0016209 MetaCyc: PWY-6854 A4G23_RS06735 659e1b7f401e50e48eb719451641f5d0 310 Pfam PF08338 Domain of unknown function (DUF1731) 263 308 6.6E-19 T 10-11-2016 IPR013549 Domain of unknown function DUF1731 A4G23_RS06735 659e1b7f401e50e48eb719451641f5d0 310 Gene3D G3DSA:3.40.50.720 9 251 7.0E-29 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS06735 659e1b7f401e50e48eb719451641f5d0 310 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 18 306 2.0E-100 T 10-11-2016 IPR010099 Epimerase family protein SDR39U1 A4G23_RS06735 659e1b7f401e50e48eb719451641f5d0 310 SUPERFAMILY SSF51735 12 306 1.1E-43 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS06735 659e1b7f401e50e48eb719451641f5d0 310 Pfam PF01370 NAD dependent epimerase/dehydratase family 19 227 1.1E-14 T 10-11-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 A4G23_RS00720 7a79e2ff6e7d615a38a53712365fe1d8 342 Gene3D G3DSA:1.10.10.10 258 321 2.3E-6 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS00720 7a79e2ff6e7d615a38a53712365fe1d8 342 SUPERFAMILY SSF46894 258 322 4.42E-6 T 10-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4G23_RS00720 7a79e2ff6e7d615a38a53712365fe1d8 342 Pfam PF11495 Archaeal transcriptional regulator TrmB 115 258 5.1E-6 T 10-11-2016 IPR021586 Transcription regulator TrmB, C-terminal A4G23_RS10100 2dfe51da7d9a608e4c55bfbe023f1f62 169 Pfam PF00731 AIR carboxylase 1 146 2.0E-65 T 10-11-2016 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A4G23_RS10100 2dfe51da7d9a608e4c55bfbe023f1f62 169 SMART SM01001 1 148 1.5E-93 T 10-11-2016 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A4G23_RS10100 2dfe51da7d9a608e4c55bfbe023f1f62 169 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 1 155 1.4E-64 T 10-11-2016 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A4G23_RS10100 2dfe51da7d9a608e4c55bfbe023f1f62 169 PIRSF PIRSF001338 1 159 5.2E-68 T 10-11-2016 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 A4G23_RS10100 2dfe51da7d9a608e4c55bfbe023f1f62 169 SUPERFAMILY SSF52255 1 157 3.27E-65 T 10-11-2016 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A4G23_RS10100 2dfe51da7d9a608e4c55bfbe023f1f62 169 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 1 152 32.362 T 10-11-2016 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A4G23_RS10100 2dfe51da7d9a608e4c55bfbe023f1f62 169 Gene3D G3DSA:3.40.50.7700 1 156 9.5E-73 T 10-11-2016 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A4G23_RS18125 c3cf87bbb7345a2d2e01d821b0f7d07c 297 Pfam PF00482 Type II secretion system (T2SS), protein F 152 277 6.3E-21 T 10-11-2016 IPR018076 Type II secretion system F domain A4G23_RS04195 48ddd95e490dc1036e156b6cc04350aa 346 Pfam PF03595 Voltage-dependent anion channel 3 318 5.9E-52 T 10-11-2016 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 A4G23_RS22575 9a4d869e164dd7cf2e75a8d550a58b55 230 Gene3D G3DSA:3.40.50.1820 4 212 3.9E-46 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS22575 9a4d869e164dd7cf2e75a8d550a58b55 230 SUPERFAMILY SSF53474 3 212 7.68E-36 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS22575 9a4d869e164dd7cf2e75a8d550a58b55 230 Pfam PF01738 Dienelactone hydrolase family 18 207 4.7E-10 T 10-11-2016 IPR002925 Dienelactone hydrolase GO:0016787 A4G23_RS09395 d8e28a1cd4dc3d9f82c234daab9486b7 208 Pfam PF13392 HNH endonuclease 161 192 2.9E-8 T 10-11-2016 IPR003615 HNH nuclease A4G23_RS09395 d8e28a1cd4dc3d9f82c234daab9486b7 208 SMART SM00507 143 194 2.3E-4 T 10-11-2016 IPR003615 HNH nuclease A4G23_RS22270 4fa47f4d06087eb8b239af3c4d2786bf 507 SUPERFAMILY SSF46785 268 326 2.73E-6 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS22270 4fa47f4d06087eb8b239af3c4d2786bf 507 SUPERFAMILY SSF52540 5 192 1.06E-8 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS22270 4fa47f4d06087eb8b239af3c4d2786bf 507 Gene3D G3DSA:1.10.10.10 269 322 2.7E-4 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS22270 4fa47f4d06087eb8b239af3c4d2786bf 507 Gene3D G3DSA:3.40.50.300 8 168 3.5E-7 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS01865 496e561b692f6e277090a3c4e60c0a15 238 SUPERFAMILY SSF56281 3 231 2.75E-45 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS01865 496e561b692f6e277090a3c4e60c0a15 238 Pfam PF00753 Metallo-beta-lactamase superfamily 32 217 1.7E-25 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS01865 496e561b692f6e277090a3c4e60c0a15 238 SMART SM00849 17 217 3.8E-29 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS01865 496e561b692f6e277090a3c4e60c0a15 238 Gene3D G3DSA:3.60.15.10 3 227 1.2E-43 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS08260 fe7091efe86ef2f4c6cb71e95e30606d 225 Pfam PF04093 rod shape-determining protein MreD 4 163 1.2E-7 T 10-11-2016 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 A4G23_RS08260 fe7091efe86ef2f4c6cb71e95e30606d 225 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 5 158 1.3E-20 T 10-11-2016 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 A4G23_RS16815 f668ad79f484f05f08e45357da79e6bc 189 SUPERFAMILY SSF160631 12 145 2.22E-13 T 10-11-2016 A4G23_RS16815 f668ad79f484f05f08e45357da79e6bc 189 Pfam PF14568 SMI1-KNR4 cell-wall 13 127 3.4E-10 T 10-11-2016 A4G23_RS16815 f668ad79f484f05f08e45357da79e6bc 189 SMART SM00860 6 139 2.3E-5 T 10-11-2016 IPR018958 SMI1/KNR4-like domain A4G23_RS16815 f668ad79f484f05f08e45357da79e6bc 189 Gene3D G3DSA:3.40.1580.10 15 48 2.5E-6 T 10-11-2016 IPR018958 SMI1/KNR4-like domain A4G23_RS12370 5cfb66b9ba6de7c6a3a42a5b3378768a 250 Pfam PF01061 ABC-2 type transporter 7 214 1.5E-23 T 10-11-2016 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A4G23_RS12370 5cfb66b9ba6de7c6a3a42a5b3378768a 250 PIRSF PIRSF006648 1 250 6.0E-62 T 10-11-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 A4G23_RS19020 1eed60b6fb9ea79f2b12ea69628991b8 304 Gene3D G3DSA:1.10.3720.10 29 291 1.8E-67 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS19020 1eed60b6fb9ea79f2b12ea69628991b8 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 288 7.9E-19 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS19020 1eed60b6fb9ea79f2b12ea69628991b8 304 SUPERFAMILY SSF161098 31 304 1.96E-71 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS11880 f3a4d957c9f00cf21888eb0252f639d4 250 Hamap MF_00991 Futalosine hydrolase [mqnB]. 41 244 25.047 T 10-11-2016 IPR019963 Futalosine hydrolase GO:0009234|GO:0016799 KEGG: 00130+3.2.2.26|MetaCyc: PWY-7374 A4G23_RS11880 f3a4d957c9f00cf21888eb0252f639d4 250 Gene3D G3DSA:3.40.50.1580 2 241 4.2E-50 T 10-11-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A4G23_RS11880 f3a4d957c9f00cf21888eb0252f639d4 250 Pfam PF01048 Phosphorylase superfamily 45 228 6.5E-15 T 10-11-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A4G23_RS11880 f3a4d957c9f00cf21888eb0252f639d4 250 SUPERFAMILY SSF53167 58 227 1.7E-27 T 10-11-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A4G23_RS11880 f3a4d957c9f00cf21888eb0252f639d4 250 TIGRFAM TIGR03664 fut_nucase: futalosine hydrolase 3 240 6.9E-67 T 10-11-2016 IPR019963 Futalosine hydrolase GO:0009234|GO:0016799 KEGG: 00130+3.2.2.26|MetaCyc: PWY-7374 A4G23_RS18945 fcfe2e5cde337a4787d0fa720cf2f8c7 547 Gene3D G3DSA:1.10.3210.10 395 537 1.6E-10 T 10-11-2016 IPR006674 HD domain A4G23_RS18945 fcfe2e5cde337a4787d0fa720cf2f8c7 547 SUPERFAMILY SSF109604 370 534 1.43E-14 T 10-11-2016 A4G23_RS10035 2a562a31cc34ce4552877226e5d2a28b 401 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 158 313 1.2E-42 T 10-11-2016 IPR004474 Cell envelope-related transcriptional attenuator domain A4G23_RS10035 2a562a31cc34ce4552877226e5d2a28b 401 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 158 313 1.8E-37 T 10-11-2016 IPR004474 Cell envelope-related transcriptional attenuator domain A4G23_RS15795 3fc6e19d79be78ab555ad2374a336b0f 244 Pfam PF01927 Mut7-C RNAse domain 90 230 3.1E-42 T 10-11-2016 IPR002782 Mut7-C RNAse domain A4G23_RS15795 3fc6e19d79be78ab555ad2374a336b0f 244 Pfam PF14451 Mut7-C ubiquitin 4 82 4.6E-23 T 10-11-2016 IPR027798 Ubiquitin Mut7-C domain A4G23_RS23530 e5cc1a77d4c84566965e85cc6c9e3e4e 267 Gene3D G3DSA:3.40.50.300 3 238 3.2E-65 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS23530 e5cc1a77d4c84566965e85cc6c9e3e4e 267 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS23530 e5cc1a77d4c84566965e85cc6c9e3e4e 267 SUPERFAMILY SSF52540 5 232 1.52E-62 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS23530 e5cc1a77d4c84566965e85cc6c9e3e4e 267 Pfam PF00005 ABC transporter 22 168 1.7E-29 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS23530 e5cc1a77d4c84566965e85cc6c9e3e4e 267 SMART SM00382 29 217 4.1E-18 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS03750 85bbdd14a00eb5568bfbf8a25cdf4be9 180 Gene3D G3DSA:1.20.1440.20 21 139 3.2E-6 T 10-11-2016 IPR023353 LemA-like domain A4G23_RS03750 85bbdd14a00eb5568bfbf8a25cdf4be9 180 SUPERFAMILY SSF140478 27 140 4.84E-6 T 10-11-2016 IPR023353 LemA-like domain A4G23_RS26670 4e796d960bad8bcb7c06e4694363589b 339 Pfam PF10648 Immunoglobulin-like domain of bacterial spore germination 242 323 2.3E-19 T 10-11-2016 IPR018911 Bacterial spore germination, immunoglobulin-like domain A4G23_RS26670 4e796d960bad8bcb7c06e4694363589b 339 SMART SM00909 130 220 6.5E-20 T 10-11-2016 IPR019606 GerMN domain A4G23_RS26670 4e796d960bad8bcb7c06e4694363589b 339 Pfam PF10646 Sporulation and spore germination 109 216 7.3E-17 T 10-11-2016 IPR019606 GerMN domain A4G23_RS24555 d8217b2ce1d626d6235ce32fdb4ce77d 179 Pfam PF13302 Acetyltransferase (GNAT) domain 21 155 5.1E-15 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS24555 d8217b2ce1d626d6235ce32fdb4ce77d 179 Gene3D G3DSA:3.40.630.30 19 161 4.5E-24 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS24555 d8217b2ce1d626d6235ce32fdb4ce77d 179 SUPERFAMILY SSF55729 20 161 2.36E-21 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS21850 5391a2529044666a26dbd0a3298c5920 93 SUPERFAMILY SSF143011 5 88 3.14E-16 T 10-11-2016 A4G23_RS21850 5391a2529044666a26dbd0a3298c5920 93 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 6 89 2.1E-8 T 10-11-2016 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family A4G23_RS21530 9d01e44effb6d89f4e1f792a879c511e 170 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 5 147 31.449 T 10-11-2016 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7206|Reactome: R-HSA-500753 A4G23_RS21530 9d01e44effb6d89f4e1f792a879c511e 170 SUPERFAMILY SSF51283 4 146 3.66E-43 T 10-11-2016 IPR029054 dUTPase-like A4G23_RS21530 9d01e44effb6d89f4e1f792a879c511e 170 Pfam PF00692 dUTPase 16 146 2.9E-30 T 10-11-2016 IPR008180 Deoxyuridine triphosphate nucleotidohydrolase/Deoxycytidine triphosphate deaminase GO:0016787|GO:0046080 A4G23_RS21530 9d01e44effb6d89f4e1f792a879c511e 170 TIGRFAM TIGR00576 dut: dUTP diphosphatase 8 146 2.5E-49 T 10-11-2016 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7206|Reactome: R-HSA-500753 A4G23_RS21530 9d01e44effb6d89f4e1f792a879c511e 170 Gene3D G3DSA:2.70.40.10 5 146 6.8E-52 T 10-11-2016 IPR029054 dUTPase-like A4G23_RS04530 c7d414bede20f5be2812685b98d87fe9 96 ProDom PD277113 MEMBRANE INNER YIDG TRANSMEMBRANE STY3975 RV2273/MT2334 MB2296 1 34 3.0E-7 T 10-11-2016 IPR020264 Uncharacterised protein family YidG A4G23_RS04530 c7d414bede20f5be2812685b98d87fe9 96 Pfam PF02656 Domain of unknown function (DUF202) 1 60 4.0E-10 T 10-11-2016 IPR003807 Domain of unknown function DUF202 A4G23_RS03595 605920dc953d040c78239b0f5799e064 335 Pfam PF13671 AAA domain 156 282 1.2E-8 T 10-11-2016 A4G23_RS03595 605920dc953d040c78239b0f5799e064 335 SUPERFAMILY SSF52540 156 326 7.19E-14 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS03595 605920dc953d040c78239b0f5799e064 335 Gene3D G3DSA:3.40.50.300 156 329 5.4E-15 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS22565 d611674d05c500324d0f799cf8af81c2 252 SUPERFAMILY SSF69349 53 178 4.63E-7 T 10-11-2016 A4G23_RS22565 d611674d05c500324d0f799cf8af81c2 252 Pfam PF07212 Hyaluronidase protein (HylP) 32 177 5.5E-16 T 10-11-2016 IPR009860 Hyaluronidase, bacterial GO:0004415|GO:0045227 KEGG: 00531+3.2.1.35 A4G23_RS04065 697e755066c29610b861a961e0147a17 163 Pfam PF00583 Acetyltransferase (GNAT) family 60 129 3.6E-12 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS04065 697e755066c29610b861a961e0147a17 163 SUPERFAMILY SSF55729 24 138 1.59E-19 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS04065 697e755066c29610b861a961e0147a17 163 Gene3D G3DSA:3.40.630.30 19 137 2.6E-26 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS03675 2b4f4735a56c549d2325533e4b8db1d1 235 SUPERFAMILY SSF56281 6 221 4.6E-48 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS03675 2b4f4735a56c549d2325533e4b8db1d1 235 SMART SM00849 12 202 9.2E-36 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS03675 2b4f4735a56c549d2325533e4b8db1d1 235 Pfam PF00753 Metallo-beta-lactamase superfamily 9 202 3.1E-27 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS03675 2b4f4735a56c549d2325533e4b8db1d1 235 Gene3D G3DSA:3.60.15.10 9 220 1.4E-49 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS16670 87c379091c59978b6db988a7e95de98c 61 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 61 25.705 T 10-11-2016 IPR023053 Ribosomal protein S14, type Z A4G23_RS16670 87c379091c59978b6db988a7e95de98c 61 Pfam PF00253 Ribosomal protein S14p/S29e 9 60 2.0E-24 T 10-11-2016 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS16670 87c379091c59978b6db988a7e95de98c 61 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 45 - T 10-11-2016 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4G23_RS16670 87c379091c59978b6db988a7e95de98c 61 SUPERFAMILY SSF57716 4 61 7.84E-22 T 10-11-2016 A4G23_RS16670 87c379091c59978b6db988a7e95de98c 61 Gene3D G3DSA:4.10.830.10 2 61 3.9E-28 T 10-11-2016 A4G23_RS03215 19030471c9f25b381226b34a383060ca 288 Gene3D G3DSA:2.40.100.10 176 287 4.6E-12 T 10-11-2016 IPR029000 Cyclophilin-like domain A4G23_RS03215 19030471c9f25b381226b34a383060ca 288 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 8 287 1.4E-78 T 10-11-2016 IPR003778 Carboxyltransferase domain, subdomain A and B A4G23_RS03215 19030471c9f25b381226b34a383060ca 288 SUPERFAMILY SSF50891 177 287 1.52E-15 T 10-11-2016 IPR029000 Cyclophilin-like domain A4G23_RS03215 19030471c9f25b381226b34a383060ca 288 Pfam PF02626 Allophanate hydrolase subunit 2 28 285 4.4E-85 T 10-11-2016 IPR003778 Carboxyltransferase domain, subdomain A and B A4G23_RS03215 19030471c9f25b381226b34a383060ca 288 SMART SM00797 27 288 2.1E-95 T 10-11-2016 IPR003778 Carboxyltransferase domain, subdomain A and B A4G23_RS17610 3d8c0a9f2f1889fc83720cbb5674bc5f 116 Gene3D G3DSA:3.30.750.24 7 93 5.8E-7 T 10-11-2016 IPR002645 STAS domain A4G23_RS17610 3d8c0a9f2f1889fc83720cbb5674bc5f 116 Pfam PF13466 STAS domain 9 90 2.8E-16 T 10-11-2016 IPR002645 STAS domain A4G23_RS17610 3d8c0a9f2f1889fc83720cbb5674bc5f 116 SUPERFAMILY SSF52091 7 93 4.12E-8 T 10-11-2016 IPR002645 STAS domain A4G23_RS04290 a410a8ff79bf1624595a49712bb90a5a 255 TIGRFAM TIGR03691 20S_bact_alpha: proteasome, alpha subunit 2 230 9.2E-116 T 10-11-2016 IPR022296 Proteasome, alpha subunit, bacterial GO:0004298|GO:0019773|GO:0051603 A4G23_RS04290 a410a8ff79bf1624595a49712bb90a5a 255 Hamap MF_00289_B Proteasome subunit alpha [prcA]. 1 234 48.965 T 10-11-2016 IPR022296 Proteasome, alpha subunit, bacterial GO:0004298|GO:0019773|GO:0051603 A4G23_RS04290 a410a8ff79bf1624595a49712bb90a5a 255 Pfam PF00227 Proteasome subunit 25 206 2.3E-28 T 10-11-2016 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5687128|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-983168 A4G23_RS04290 a410a8ff79bf1624595a49712bb90a5a 255 SUPERFAMILY SSF56235 10 229 3.66E-44 T 10-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal A4G23_RS04290 a410a8ff79bf1624595a49712bb90a5a 255 Gene3D G3DSA:3.60.20.10 3 237 2.6E-85 T 10-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal A4G23_RS13730 bb8ee0d068c9100f424acee802bf0411 286 Pfam PF08282 haloacid dehalogenase-like hydrolase 21 279 1.6E-48 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS13730 bb8ee0d068c9100f424acee802bf0411 286 SUPERFAMILY SSF56784 17 283 1.85E-56 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS13730 bb8ee0d068c9100f424acee802bf0411 286 Gene3D G3DSA:3.40.50.1000 187 283 9.1E-48 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS13730 bb8ee0d068c9100f424acee802bf0411 286 Gene3D G3DSA:3.40.50.1000 16 88 9.1E-48 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS13730 bb8ee0d068c9100f424acee802bf0411 286 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 20 279 1.8E-44 T 10-11-2016 IPR000150 Cof protein GO:0016787 A4G23_RS21945 2700edc46b3d03957bb3d607287a4550 131 Pfam PF01042 Endoribonuclease L-PSP 26 130 1.6E-18 T 10-11-2016 IPR006175 YjgF/YER057c/UK114 family A4G23_RS21945 2700edc46b3d03957bb3d607287a4550 131 Gene3D G3DSA:3.30.1330.40 8 130 4.3E-31 T 10-11-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like A4G23_RS21945 2700edc46b3d03957bb3d607287a4550 131 SUPERFAMILY SSF55298 26 130 3.77E-26 T 10-11-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like A4G23_RS21970 598f290666cb6556ad334001256dbcac 205 SUPERFAMILY SSF52218 7 191 6.16E-44 T 10-11-2016 IPR029039 Flavoprotein-like domain A4G23_RS21970 598f290666cb6556ad334001256dbcac 205 Pfam PF03358 NADPH-dependent FMN reductase 48 128 4.2E-8 T 10-11-2016 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 A4G23_RS21970 598f290666cb6556ad334001256dbcac 205 Gene3D G3DSA:3.40.50.360 7 194 4.8E-53 T 10-11-2016 IPR029039 Flavoprotein-like domain A4G23_RS14365 cdb74c1b57277318d1e31a962041c777 223 SUPERFAMILY SSF55729 114 191 7.5E-22 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS14365 cdb74c1b57277318d1e31a962041c777 223 SUPERFAMILY SSF55729 27 85 7.5E-22 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS14365 cdb74c1b57277318d1e31a962041c777 223 Pfam PF00583 Acetyltransferase (GNAT) family 109 180 6.3E-14 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS14365 cdb74c1b57277318d1e31a962041c777 223 Gene3D G3DSA:3.40.630.30 28 189 3.5E-24 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS03310 be9309a541b80cacdebfba2821893753 348 Pfam PF12833 Helix-turn-helix domain 257 333 1.2E-17 T 10-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4G23_RS03310 be9309a541b80cacdebfba2821893753 348 SMART SM00342 250 332 9.9E-23 T 10-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4G23_RS03310 be9309a541b80cacdebfba2821893753 348 SUPERFAMILY SSF46689 285 335 6.4E-10 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS03310 be9309a541b80cacdebfba2821893753 348 Gene3D G3DSA:1.10.10.60 285 336 1.8E-11 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS03310 be9309a541b80cacdebfba2821893753 348 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 21 207 7.6E-36 T 10-11-2016 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal A4G23_RS18640 8e36f3a14922672cade516ff3f61b0dc 283 Pfam PF12697 Alpha/beta hydrolase family 41 278 1.0E-16 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS18640 8e36f3a14922672cade516ff3f61b0dc 283 SUPERFAMILY SSF53474 38 282 4.15E-38 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS18640 8e36f3a14922672cade516ff3f61b0dc 283 PRINTS PR00111 Alpha/beta hydrolase fold signature 111 124 6.4E-5 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS18640 8e36f3a14922672cade516ff3f61b0dc 283 PRINTS PR00111 Alpha/beta hydrolase fold signature 125 138 6.4E-5 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS18640 8e36f3a14922672cade516ff3f61b0dc 283 PRINTS PR00111 Alpha/beta hydrolase fold signature 64 79 6.4E-5 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS18640 8e36f3a14922672cade516ff3f61b0dc 283 PRINTS PR00111 Alpha/beta hydrolase fold signature 230 244 6.4E-5 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS18640 8e36f3a14922672cade516ff3f61b0dc 283 Gene3D G3DSA:3.40.50.1820 33 283 2.5E-39 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS16245 02746050c9d418cf2ad642240e32f76d 417 PIRSF PIRSF006060 2 409 5.7E-65 T 10-11-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A4G23_RS16245 02746050c9d418cf2ad642240e32f76d 417 Pfam PF13520 Amino acid permease 9 364 2.4E-39 T 10-11-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A4G23_RS08215 13c77f695c69df6e33c8e9bb2a01a1c8 260 TIGRFAM TIGR03936 sam_1_link_chp: radical SAM-linked protein 3 215 2.3E-53 T 10-11-2016 IPR018768 Domain of unknown function DUF2344 A4G23_RS08215 13c77f695c69df6e33c8e9bb2a01a1c8 260 Pfam PF10105 Uncharacterized protein conserved in bacteria (DUF2344) 3 191 4.8E-48 T 10-11-2016 IPR018768 Domain of unknown function DUF2344 A4G23_RS06015 ba42b8ac5b263d5597d2f3a8d7704286 229 Pfam PF09534 Tryptophan-associated transmembrane protein (Trp_oprn_chp) 37 219 5.8E-50 T 10-11-2016 IPR019051 Trp biosynthesis associated, transmembrane protein, Oprn/Chp A4G23_RS06015 ba42b8ac5b263d5597d2f3a8d7704286 229 TIGRFAM TIGR02234 trp_oprn_chp: membrane protein, TIGR02234 family 30 220 3.4E-47 T 10-11-2016 IPR011746 Trp biosynthesis associated, conserved hypothetical membrane protein A4G23_RS01745 2acf876f95f1ba388ab1414d45114620 263 Pfam PF01177 Asp/Glu/Hydantoin racemase 28 212 1.8E-14 T 10-11-2016 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4G23_RS01745 2acf876f95f1ba388ab1414d45114620 263 Gene3D G3DSA:3.40.50.1860 2 152 6.0E-33 T 10-11-2016 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4G23_RS01745 2acf876f95f1ba388ab1414d45114620 263 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 67 75 - T 10-11-2016 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4G23_RS01745 2acf876f95f1ba388ab1414d45114620 263 SUPERFAMILY SSF53681 2 103 2.09E-21 T 10-11-2016 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4G23_RS01745 2acf876f95f1ba388ab1414d45114620 263 SUPERFAMILY SSF53681 106 221 5.01E-20 T 10-11-2016 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4G23_RS21405 4c5fcf0dac2f0087d64849a4e80ea64d 351 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 7 182 1.9E-43 T 10-11-2016 IPR003495 CobW/HypB/UreG, nucleotide-binding domain A4G23_RS21405 4c5fcf0dac2f0087d64849a4e80ea64d 351 SUPERFAMILY SSF90002 233 323 7.59E-18 T 10-11-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal A4G23_RS21405 4c5fcf0dac2f0087d64849a4e80ea64d 351 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 233 323 1.4E-20 T 10-11-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal A4G23_RS21405 4c5fcf0dac2f0087d64849a4e80ea64d 351 SMART SM00833 232 323 1.4E-14 T 10-11-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal A4G23_RS21405 4c5fcf0dac2f0087d64849a4e80ea64d 351 SUPERFAMILY SSF52540 5 202 5.43E-32 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS21405 4c5fcf0dac2f0087d64849a4e80ea64d 351 Gene3D G3DSA:3.30.1220.10 221 323 2.7E-17 T 10-11-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal A4G23_RS21405 4c5fcf0dac2f0087d64849a4e80ea64d 351 Gene3D G3DSA:3.40.50.300 4 196 1.8E-51 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS04595 64ecbc6eddd7ebf57a12aa6f7cf6f474 95 Pfam PF05360 yiaA/B two helix domain 14 66 5.6E-18 T 10-11-2016 IPR008024 YiaAB two helix A4G23_RS16480 01bb53596c52c814879c591a1802c696 149 Gene3D G3DSA:1.10.260.40 32 76 1.6E-8 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS16480 01bb53596c52c814879c591a1802c696 149 SUPERFAMILY SSF47413 31 77 5.35E-8 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS16480 01bb53596c52c814879c591a1802c696 149 Pfam PF01381 Helix-turn-helix 33 73 3.5E-6 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS16480 01bb53596c52c814879c591a1802c696 149 SMART SM00530 12 75 3.5E-5 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS20605 508df7f4cafc59fa2430f3f3231690d5 377 Pfam PF01148 Cytidylyltransferase family 117 372 1.6E-62 T 10-11-2016 A4G23_RS20605 508df7f4cafc59fa2430f3f3231690d5 377 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 331 357 - T 10-11-2016 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981 A4G23_RS03835 5a5766184729120b90f92fb8460badf3 186 Gene3D G3DSA:1.10.3300.10 3 181 2.7E-53 T 10-11-2016 IPR023286 ABATE domain A4G23_RS03835 5a5766184729120b90f92fb8460badf3 186 SUPERFAMILY SSF160904 2 179 1.57E-49 T 10-11-2016 A4G23_RS03835 5a5766184729120b90f92fb8460badf3 186 Pfam PF07336 Putative stress-induced transcription regulator 13 130 8.0E-15 T 10-11-2016 IPR010852 Putative stress-induced transcription regulator A4G23_RS03835 5a5766184729120b90f92fb8460badf3 186 Pfam PF11706 CGNR zinc finger 137 180 4.5E-18 T 10-11-2016 IPR021005 Zinc finger, CGNR A4G23_RS05555 886148e63b3e162f858e6bac33354ba7 157 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 3 140 1.2E-46 T 10-11-2016 A4G23_RS05555 886148e63b3e162f858e6bac33354ba7 157 SUPERFAMILY SSF82649 2 143 2.88E-43 T 10-11-2016 A4G23_RS05555 886148e63b3e162f858e6bac33354ba7 157 Gene3D G3DSA:3.90.1010.10 5 151 1.0E-44 T 10-11-2016 A4G23_RS05555 886148e63b3e162f858e6bac33354ba7 157 Pfam PF01592 NifU-like N terminal domain 6 129 2.9E-25 T 10-11-2016 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 A4G23_RS14300 24dba45c480103282020316c87758333 349 Pfam PF07070 SpoOM protein 3 217 5.6E-78 T 10-11-2016 IPR009776 Sporulation stage 0, protein M A4G23_RS14140 bce4ad239c486a293d38f899580561c9 297 Pfam PF04989 Cephalosporin hydroxylase 90 291 2.0E-29 T 10-11-2016 IPR007072 Rhamnosyl O-methyltransferase/Cephalosporin hydroxylase GO:0008168|GO:0008610 A4G23_RS14140 bce4ad239c486a293d38f899580561c9 297 SUPERFAMILY SSF53335 85 263 2.74E-24 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS14140 bce4ad239c486a293d38f899580561c9 297 Gene3D G3DSA:3.40.50.150 79 236 3.8E-12 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS02130 bd251b4ca63a95f2b762083b120cb4d8 249 Gene3D G3DSA:3.40.50.150 48 164 7.5E-25 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS02130 bd251b4ca63a95f2b762083b120cb4d8 249 SUPERFAMILY SSF53335 29 186 2.05E-28 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS02130 bd251b4ca63a95f2b762083b120cb4d8 249 Pfam PF08241 Methyltransferase domain 58 146 3.6E-16 T 10-11-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 A4G23_RS17360 4589f5d934bb0ae1d470dec74f5d2257 62 Gene3D G3DSA:3.30.70.20 1 61 3.8E-15 T 10-11-2016 A4G23_RS17360 4589f5d934bb0ae1d470dec74f5d2257 62 Pfam PF13459 4Fe-4S single cluster domain 3 58 1.6E-14 T 10-11-2016 A4G23_RS17360 4589f5d934bb0ae1d470dec74f5d2257 62 SUPERFAMILY SSF54862 2 60 1.8E-12 T 10-11-2016 A4G23_RS17360 4589f5d934bb0ae1d470dec74f5d2257 62 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 8.8E-8 T 10-11-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A4G23_RS17360 4589f5d934bb0ae1d470dec74f5d2257 62 PRINTS PR00352 3Fe-4S ferredoxin signature 45 57 8.8E-8 T 10-11-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A4G23_RS17360 4589f5d934bb0ae1d470dec74f5d2257 62 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 8.8E-8 T 10-11-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A4G23_RS24855 bc514b18045c8ff17cc32c9fbdb0dbfe 653 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 290 312 - T 10-11-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A4G23_RS24855 bc514b18045c8ff17cc32c9fbdb0dbfe 653 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 476 491 - T 10-11-2016 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 A4G23_RS24855 bc514b18045c8ff17cc32c9fbdb0dbfe 653 Pfam PF01066 CDP-alcohol phosphatidyltransferase 246 312 1.3E-8 T 10-11-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A4G23_RS21130 2481498f65804951e290c323c0dc6a91 240 Pfam PF03591 AzlC protein 30 166 1.1E-28 T 10-11-2016 IPR011606 Branched-chain amino acid transport, permease A4G23_RS13755 8ef2f991bcc57bf0d9e7df511ac9b88f 323 SMART SM00382 25 209 5.1E-11 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS13755 8ef2f991bcc57bf0d9e7df511ac9b88f 323 SUPERFAMILY SSF52540 7 210 1.31E-55 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS13755 8ef2f991bcc57bf0d9e7df511ac9b88f 323 Gene3D G3DSA:3.40.50.300 2 223 4.0E-61 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS13755 8ef2f991bcc57bf0d9e7df511ac9b88f 323 Pfam PF00005 ABC transporter 17 160 1.4E-26 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS24250 b1876023d21686a7f0d733d26a8c89b5 373 Pfam PF02595 Glycerate kinase family 1 370 9.1E-126 T 10-11-2016 IPR004381 Glycerate kinase GO:0008887|GO:0031388 A4G23_RS24250 b1876023d21686a7f0d733d26a8c89b5 373 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 1 369 9.3E-113 T 10-11-2016 IPR004381 Glycerate kinase GO:0008887|GO:0031388 A4G23_RS24250 b1876023d21686a7f0d733d26a8c89b5 373 SUPERFAMILY SSF110738 1 370 1.83E-110 T 10-11-2016 IPR004381 Glycerate kinase GO:0008887|GO:0031388 A4G23_RS24250 b1876023d21686a7f0d733d26a8c89b5 373 Gene3D G3DSA:3.90.1510.10 40 273 8.1E-83 T 10-11-2016 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 A4G23_RS24250 b1876023d21686a7f0d733d26a8c89b5 373 PIRSF PIRSF006078 1 373 6.6E-117 T 10-11-2016 IPR004381 Glycerate kinase GO:0008887|GO:0031388 A4G23_RS09980 ff31a270c675b2613c6319583c4044c0 87 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 87 18.896 T 10-11-2016 IPR003482 Transcription factor WhiB A4G23_RS09980 ff31a270c675b2613c6319583c4044c0 87 Pfam PF02467 Transcription factor WhiB 19 82 6.1E-27 T 10-11-2016 IPR003482 Transcription factor WhiB A4G23_RS04620 23cf01637fbe1d04e85f976865958231 639 Gene3D G3DSA:1.20.1560.10 70 364 3.9E-5 T 10-11-2016 A4G23_RS04620 23cf01637fbe1d04e85f976865958231 639 Gene3D G3DSA:3.40.50.300 394 624 1.7E-68 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS04620 23cf01637fbe1d04e85f976865958231 639 ProSitePatterns PS00211 ABC transporters family signature. 537 551 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS04620 23cf01637fbe1d04e85f976865958231 639 SUPERFAMILY SSF52540 389 636 9.49E-68 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS04620 23cf01637fbe1d04e85f976865958231 639 Pfam PF00005 ABC transporter 412 565 2.3E-28 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS04620 23cf01637fbe1d04e85f976865958231 639 SMART SM00382 421 617 2.8E-15 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS04620 23cf01637fbe1d04e85f976865958231 639 SUPERFAMILY SSF90123 65 367 1.03E-10 T 10-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A4G23_RS03715 0a581cc8c53ff1761360c248fb490235 150 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 1 67 8.7E-15 T 10-11-2016 IPR003849 Preprotein translocase YajC A4G23_RS03715 0a581cc8c53ff1761360c248fb490235 150 Pfam PF02699 Preprotein translocase subunit 1 64 3.3E-15 T 10-11-2016 IPR003849 Preprotein translocase YajC A4G23_RS03715 0a581cc8c53ff1761360c248fb490235 150 SMART SM01323 1 67 8.2E-13 T 10-11-2016 IPR003849 Preprotein translocase YajC A4G23_RS14900 fbed329d428f35ac7228d05146b274b9 299 SUPERFAMILY SSF56784 11 219 3.92E-32 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS14900 fbed329d428f35ac7228d05146b274b9 299 Gene3D G3DSA:3.40.50.1000 86 236 1.1E-48 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS14900 fbed329d428f35ac7228d05146b274b9 299 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 14 203 3.8E-21 T 10-11-2016 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 A4G23_RS14900 fbed329d428f35ac7228d05146b274b9 299 Pfam PF12710 haloacid dehalogenase-like hydrolase 15 201 8.0E-32 T 10-11-2016 A4G23_RS14900 fbed329d428f35ac7228d05146b274b9 299 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 14 214 4.6E-60 T 10-11-2016 IPR006385 HAD-superfamily hydrolase, subfamily IB, PSPase-like, bacterial A4G23_RS19800 50288852c59661f69dc2e5585134eca9 231 SUPERFAMILY SSF47413 20 82 2.84E-5 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS19800 50288852c59661f69dc2e5585134eca9 231 SUPERFAMILY SSF47413 83 142 9.29E-7 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS19800 50288852c59661f69dc2e5585134eca9 231 Gene3D G3DSA:1.10.260.40 20 80 1.2E-8 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS19800 50288852c59661f69dc2e5585134eca9 231 Pfam PF13560 Helix-turn-helix domain 85 141 1.8E-7 T 10-11-2016 A4G23_RS19800 50288852c59661f69dc2e5585134eca9 231 SMART SM00530 85 141 8.7E-6 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS19800 50288852c59661f69dc2e5585134eca9 231 SMART SM00530 18 79 0.045 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS19800 50288852c59661f69dc2e5585134eca9 231 Gene3D G3DSA:1.10.260.40 85 142 5.2E-7 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS07770 8ea7f66228a64ebaaef07534164d1669 143 SUPERFAMILY SSF54593 4 130 1.34E-23 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS07770 8ea7f66228a64ebaaef07534164d1669 143 Gene3D G3DSA:3.10.180.10 1 132 7.0E-31 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS27145 8e78afe3a475b5d187a68787f311494b 228 Pfam PF01955 Adenosylcobinamide amidohydrolase 38 219 1.1E-47 T 10-11-2016 IPR002808 Adenosylcobinamide amidohydrolase, CbiZ A4G23_RS18355 b43f4d97b662b30839d4193a5a6a1545 83 Pfam PF04149 Domain of unknown function (DUF397) 16 68 3.2E-17 T 10-11-2016 IPR007278 Domain of unknown function DUF397 A4G23_RS14450 826a8d2185f5b794d63723c9d26d2898 105 SUPERFAMILY SSF50022 5 86 8.73E-13 T 10-11-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A4G23_RS14450 826a8d2185f5b794d63723c9d26d2898 105 Gene3D G3DSA:2.102.10.10 19 60 1.2E-5 T 10-11-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A4G23_RS22300 c0382c32535050f5fe8008d215d39c7a 477 SMART SM00244 24 205 6.1E-4 T 10-11-2016 IPR001107 Band 7 domain A4G23_RS22300 c0382c32535050f5fe8008d215d39c7a 477 Pfam PF01145 SPFH domain / Band 7 family 29 219 4.4E-21 T 10-11-2016 IPR001107 Band 7 domain A4G23_RS22300 c0382c32535050f5fe8008d215d39c7a 477 Pfam PF15975 Flotillin 344 434 3.6E-11 T 10-11-2016 IPR031905 Flotillin, C-terminal domain Reactome: R-HSA-8849932 A4G23_RS22300 c0382c32535050f5fe8008d215d39c7a 477 SUPERFAMILY SSF117892 71 210 2.09E-26 T 10-11-2016 IPR001107 Band 7 domain A4G23_RS15130 73701531eb781c68857b8978ecd26882 446 Gene3D G3DSA:1.10.630.10 54 425 5.3E-32 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS15130 73701531eb781c68857b8978ecd26882 446 SUPERFAMILY SSF48264 55 439 9.3E-34 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS15130 73701531eb781c68857b8978ecd26882 446 Pfam PF00067 Cytochrome P450 298 418 6.8E-18 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS26720 81ff81f533125ea0bba38b50a3cf1292 136 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 132 7.5E-16 T 10-11-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4G23_RS26720 81ff81f533125ea0bba38b50a3cf1292 136 Gene3D G3DSA:3.10.180.10 7 134 2.3E-29 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS26720 81ff81f533125ea0bba38b50a3cf1292 136 SUPERFAMILY SSF54593 1 134 6.18E-27 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS03155 7eea6e1fa2ecf2fc55154273d1fa4863 141 Pfam PF05331 Protein of unknown function (DUF742) 25 141 5.1E-35 T 10-11-2016 IPR007995 Protein of unknown function DUF742 A4G23_RS00005 2c029aa2bb55f837106b7514bff47450 817 Gene3D G3DSA:3.40.50.300 220 258 8.4E-9 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS00005 2c029aa2bb55f837106b7514bff47450 817 Gene3D G3DSA:3.40.50.300 300 388 8.4E-9 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS00005 2c029aa2bb55f837106b7514bff47450 817 SUPERFAMILY SSF52540 201 258 2.1E-16 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS00005 2c029aa2bb55f837106b7514bff47450 817 SUPERFAMILY SSF52540 2 147 2.1E-16 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS00005 2c029aa2bb55f837106b7514bff47450 817 SUPERFAMILY SSF52540 300 388 2.1E-16 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS00005 2c029aa2bb55f837106b7514bff47450 817 Pfam PF03457 Helicase associated domain 506 574 2.9E-10 T 10-11-2016 IPR005114 Helicase-associated A4G23_RS04350 17306fe1dfc2bfc10786be620fcd652b 529 Gene3D G3DSA:3.10.105.10 285 497 1.3E-42 T 10-11-2016 A4G23_RS04350 17306fe1dfc2bfc10786be620fcd652b 529 Gene3D G3DSA:3.90.76.10 49 204 4.9E-34 T 10-11-2016 A4G23_RS04350 17306fe1dfc2bfc10786be620fcd652b 529 SUPERFAMILY SSF53850 34 527 2.95E-99 T 10-11-2016 A4G23_RS04350 17306fe1dfc2bfc10786be620fcd652b 529 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 81 447 1.2E-74 T 10-11-2016 IPR000914 Solute-binding protein family 5 domain A4G23_RS04350 17306fe1dfc2bfc10786be620fcd652b 529 PIRSF PIRSF002741 5 525 9.7E-68 T 10-11-2016 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A4G23_RS08920 fd36e04709f80627b5b0af36e8cd14c6 219 Pfam PF13707 RloB-like protein 24 212 4.7E-24 T 10-11-2016 IPR025591 RloB-like protein A4G23_RS06110 7c524a26d3bf87193aa23fae6ee33efe 436 Pfam PF01936 NYN domain 9 169 2.2E-11 T 10-11-2016 IPR021139 NYN domain, limkain-b1-type A4G23_RS06110 7c524a26d3bf87193aa23fae6ee33efe 436 Gene3D G3DSA:3.40.50.1010 5 174 2.3E-16 T 10-11-2016 IPR029060 PIN domain-like A4G23_RS23870 35722cfe1adbc0f0811ad35b58c7ebd2 189 Gene3D G3DSA:3.90.550.10 2 188 8.4E-29 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS23870 35722cfe1adbc0f0811ad35b58c7ebd2 189 Pfam PF12804 MobA-like NTP transferase domain 1 162 6.0E-33 T 10-11-2016 IPR025877 MobA-like NTP transferase A4G23_RS23870 35722cfe1adbc0f0811ad35b58c7ebd2 189 SUPERFAMILY SSF53448 1 185 3.38E-28 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS16360 baf67aa7fc059fa0f1ed6305ff071a1e 176 SUPERFAMILY SSF160369 1 168 1.03E-52 T 10-11-2016 A4G23_RS16360 baf67aa7fc059fa0f1ed6305ff071a1e 176 ProSitePatterns PS01109 Ribosomal protein L10 signature. 6 40 - T 10-11-2016 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS16360 baf67aa7fc059fa0f1ed6305ff071a1e 176 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 1 158 25.388 T 10-11-2016 IPR022973 Ribosomal protein L10 A4G23_RS16360 baf67aa7fc059fa0f1ed6305ff071a1e 176 Pfam PF00466 Ribosomal protein L10 2 98 9.9E-27 T 10-11-2016 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 A4G23_RS26320 8cc748c0af2dd685ced6524ec029097d 79 SUPERFAMILY SSF47336 5 72 1.02E-17 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS26320 8cc748c0af2dd685ced6524ec029097d 79 Gene3D G3DSA:1.10.1200.10 5 74 4.7E-19 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS26320 8cc748c0af2dd685ced6524ec029097d 79 SMART SM00823 Phosphopantetheine attachment site 7 76 3.9E-11 T 10-11-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A4G23_RS26320 8cc748c0af2dd685ced6524ec029097d 79 Pfam PF00550 Phosphopantetheine attachment site 10 71 2.5E-15 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS21275 ed63f95f34cb5114dcef9e70d7ca00cf 386 Gene3D G3DSA:2.40.10.10 151 253 1.0E-6 T 10-11-2016 A4G23_RS21275 ed63f95f34cb5114dcef9e70d7ca00cf 386 SUPERFAMILY SSF50494 130 367 1.09E-13 T 10-11-2016 IPR009003 Peptidase S1, PA clan A4G23_RS23240 1e5fe34d31724a174a9cedb57eebeb5a 255 Pfam PF13649 Methyltransferase domain 51 149 6.2E-14 T 10-11-2016 A4G23_RS23240 1e5fe34d31724a174a9cedb57eebeb5a 255 Gene3D G3DSA:3.40.50.150 12 252 1.9E-27 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS23240 1e5fe34d31724a174a9cedb57eebeb5a 255 SUPERFAMILY SSF53335 14 194 6.79E-27 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS17595 4c6e885e199b11e1f7fc7092770cd472 423 Pfam PF02653 Branched-chain amino acid transport system / permease component 60 349 1.5E-33 T 10-11-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 A4G23_RS08435 822656a74b93f62106396b7ae82240f0 318 SUPERFAMILY SSF103481 180 285 6.8E-14 T 10-11-2016 A4G23_RS08435 822656a74b93f62106396b7ae82240f0 318 SUPERFAMILY SSF103481 47 136 3.01E-13 T 10-11-2016 A4G23_RS08435 822656a74b93f62106396b7ae82240f0 318 Pfam PF00892 EamA-like transporter family 144 278 4.1E-22 T 10-11-2016 IPR000620 EamA domain GO:0016020|GO:0016021 A4G23_RS08435 822656a74b93f62106396b7ae82240f0 318 Pfam PF00892 EamA-like transporter family 10 134 1.6E-12 T 10-11-2016 IPR000620 EamA domain GO:0016020|GO:0016021 A4G23_RS15215 1967653790690c19f318d6c8a4289054 485 Gene3D G3DSA:3.40.605.10 11 267 3.5E-77 T 10-11-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A4G23_RS15215 1967653790690c19f318d6c8a4289054 485 SUPERFAMILY SSF53720 10 477 2.23E-150 T 10-11-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A4G23_RS15215 1967653790690c19f318d6c8a4289054 485 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 280 291 - T 10-11-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 A4G23_RS15215 1967653790690c19f318d6c8a4289054 485 Gene3D G3DSA:3.40.309.10 268 450 5.4E-66 T 10-11-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 A4G23_RS15215 1967653790690c19f318d6c8a4289054 485 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 252 259 - T 10-11-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 A4G23_RS15215 1967653790690c19f318d6c8a4289054 485 Pfam PF00171 Aldehyde dehydrogenase family 25 474 4.4E-154 T 10-11-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A4G23_RS09035 4fac2c05c5e1b665de9d6bc43017671e 173 Gene3D G3DSA:3.40.50.620 39 173 1.7E-33 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS09035 4fac2c05c5e1b665de9d6bc43017671e 173 PRINTS PR01438 Universal stress protein signature 151 173 7.3E-7 T 10-11-2016 IPR006015 Universal stress protein A A4G23_RS09035 4fac2c05c5e1b665de9d6bc43017671e 173 PRINTS PR01438 Universal stress protein signature 37 55 7.3E-7 T 10-11-2016 IPR006015 Universal stress protein A A4G23_RS09035 4fac2c05c5e1b665de9d6bc43017671e 173 Pfam PF00582 Universal stress protein family 40 173 3.7E-23 T 10-11-2016 IPR006016 UspA GO:0006950 A4G23_RS09035 4fac2c05c5e1b665de9d6bc43017671e 173 SUPERFAMILY SSF52402 40 173 5.02E-22 T 10-11-2016 A4G23_RS15185 f6ad981ff30a48572c84afee3dff6ed4 84 SUPERFAMILY SSF143800 2 80 1.73E-18 T 10-11-2016 A4G23_RS15185 f6ad981ff30a48572c84afee3dff6ed4 84 Hamap MF_00502 50S ribosomal protein L31 type B [rpmE2]. 1 81 23.566 T 10-11-2016 IPR027493 Ribosomal protein L31 type B GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS15185 f6ad981ff30a48572c84afee3dff6ed4 84 Pfam PF01197 Ribosomal protein L31 2 79 5.0E-26 T 10-11-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS15185 f6ad981ff30a48572c84afee3dff6ed4 84 TIGRFAM TIGR00105 L31: ribosomal protein bL31 3 80 2.1E-16 T 10-11-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS15185 f6ad981ff30a48572c84afee3dff6ed4 84 PRINTS PR01249 Ribosomal protein L31 signature 2 19 5.0E-16 T 10-11-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS15185 f6ad981ff30a48572c84afee3dff6ed4 84 PRINTS PR01249 Ribosomal protein L31 signature 60 78 5.0E-16 T 10-11-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS15185 f6ad981ff30a48572c84afee3dff6ed4 84 PRINTS PR01249 Ribosomal protein L31 signature 45 60 5.0E-16 T 10-11-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4G23_RS26965 d9628838fb1751d63f910c3559b47950 289 SUPERFAMILY SSF103481 33 116 1.7E-7 T 10-11-2016 A4G23_RS07910 a279424a861be3cdfe389a3907fe4f23 119 PRINTS PR00332 Histidine triad family signature 10 26 4.3E-19 T 10-11-2016 IPR001310 Histidine triad (HIT) protein A4G23_RS07910 a279424a861be3cdfe389a3907fe4f23 119 PRINTS PR00332 Histidine triad family signature 31 49 4.3E-19 T 10-11-2016 IPR001310 Histidine triad (HIT) protein A4G23_RS07910 a279424a861be3cdfe389a3907fe4f23 119 PRINTS PR00332 Histidine triad family signature 99 109 4.3E-19 T 10-11-2016 IPR001310 Histidine triad (HIT) protein A4G23_RS07910 a279424a861be3cdfe389a3907fe4f23 119 Pfam PF01230 HIT domain 17 112 2.6E-24 T 10-11-2016 IPR001310 Histidine triad (HIT) protein A4G23_RS07910 a279424a861be3cdfe389a3907fe4f23 119 Gene3D G3DSA:3.30.428.10 4 119 3.0E-37 T 10-11-2016 IPR011146 HIT-like domain GO:0003824 A4G23_RS07910 a279424a861be3cdfe389a3907fe4f23 119 SUPERFAMILY SSF54197 7 118 1.05E-33 T 10-11-2016 IPR011146 HIT-like domain GO:0003824 A4G23_RS21150 8741b7cac363639073d5727d00a82bd7 379 Pfam PF01594 Domain of unknown function DUF20 15 335 2.2E-74 T 10-11-2016 IPR002549 Transmembrane protein TqsA-like A4G23_RS10585 2d92fb6cd73c87c71aa6bd86df288306 224 SUPERFAMILY SSF48498 101 211 2.48E-8 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS10585 2d92fb6cd73c87c71aa6bd86df288306 224 SUPERFAMILY SSF46689 20 100 2.36E-21 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS10585 2d92fb6cd73c87c71aa6bd86df288306 224 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 47 2.1E-10 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS10585 2d92fb6cd73c87c71aa6bd86df288306 224 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 55 78 2.1E-10 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS10585 2d92fb6cd73c87c71aa6bd86df288306 224 Pfam PF00440 Bacterial regulatory proteins, tetR family 34 78 4.2E-17 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS10585 2d92fb6cd73c87c71aa6bd86df288306 224 ProSitePatterns PS01081 TetR-type HTH domain signature. 46 76 - T 10-11-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A4G23_RS10585 2d92fb6cd73c87c71aa6bd86df288306 224 Gene3D G3DSA:1.10.357.10 16 209 3.6E-47 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS06100 a9708c8b6c493f09c3f48a228a8294fa 276 Pfam PF01061 ABC-2 type transporter 51 236 2.5E-11 T 10-11-2016 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A4G23_RS01905 ed123eb39b49bb08877595f0209b81df 211 Pfam PF03729 Short repeat of unknown function (DUF308) 46 104 1.1E-9 T 10-11-2016 IPR005325 Protein of unknown function DUF308, membrane A4G23_RS01905 ed123eb39b49bb08877595f0209b81df 211 Pfam PF03729 Short repeat of unknown function (DUF308) 99 158 4.3E-9 T 10-11-2016 IPR005325 Protein of unknown function DUF308, membrane A4G23_RS01905 ed123eb39b49bb08877595f0209b81df 211 Pfam PF03729 Short repeat of unknown function (DUF308) 157 199 2.3E-4 T 10-11-2016 IPR005325 Protein of unknown function DUF308, membrane A4G23_RS19555 660a0ce59e61e98e5b0bdfec6318d725 178 Pfam PF00430 ATP synthase B/B' CF(0) 20 149 1.8E-25 T 10-11-2016 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 A4G23_RS19555 660a0ce59e61e98e5b0bdfec6318d725 178 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 24 170 2.6E-24 T 10-11-2016 IPR005864 ATPase, F0 complex, subunit B, bacterial GO:0015078|GO:0015986|GO:0045263 A4G23_RS19555 660a0ce59e61e98e5b0bdfec6318d725 178 Hamap MF_01398 ATP synthase subunit b [atpF]. 4 170 12.021 T 10-11-2016 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 A4G23_RS19555 660a0ce59e61e98e5b0bdfec6318d725 178 SUPERFAMILY SSF81573 76 134 1.57E-10 T 10-11-2016 IPR028987 F-type ATP synthase subunit B-like, membrane domain A4G23_RS19555 660a0ce59e61e98e5b0bdfec6318d725 178 Gene3D G3DSA:1.20.5.620 76 135 9.1E-12 T 10-11-2016 IPR028987 F-type ATP synthase subunit B-like, membrane domain A4G23_RS04970 24301989eabfbd7a07a932b6de665296 344 Gene3D G3DSA:1.10.3470.10 18 340 3.4E-92 T 10-11-2016 IPR029022 ABC transporter, BtuC-like A4G23_RS04970 24301989eabfbd7a07a932b6de665296 344 Pfam PF01032 FecCD transport family 32 336 4.5E-83 T 10-11-2016 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 A4G23_RS04970 24301989eabfbd7a07a932b6de665296 344 SUPERFAMILY SSF81345 13 336 1.44E-70 T 10-11-2016 IPR029022 ABC transporter, BtuC-like A4G23_RS17075 b762a49226a12556af2d87f29aa41e79 466 Pfam PF04024 PspC domain 24 76 3.1E-13 T 10-11-2016 IPR007168 Phage shock protein, PspC, N-terminal A4G23_RS02805 63efa47df5a043fcd55675f18f9192a5 560 Pfam PF05960 Bacterial protein of unknown function (DUF885) 25 556 1.0E-141 T 10-11-2016 IPR010281 Protein of unknown function DUF885 A4G23_RS17220 fbb0fe5d58a5c77e92a5e5d4429f7c7a 304 Pfam PF13560 Helix-turn-helix domain 17 77 1.8E-10 T 10-11-2016 A4G23_RS17220 fbb0fe5d58a5c77e92a5e5d4429f7c7a 304 Gene3D G3DSA:1.10.260.40 12 65 3.1E-9 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS17220 fbb0fe5d58a5c77e92a5e5d4429f7c7a 304 SMART SM00530 20 75 1.2E-6 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS17220 fbb0fe5d58a5c77e92a5e5d4429f7c7a 304 SUPERFAMILY SSF47413 16 70 8.45E-9 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS21135 2f50d94e683e16cd2dcf4957e4260228 105 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 6 100 1.1E-10 T 10-11-2016 IPR008407 Branched-chain amino acid transport, AzlD A4G23_RS03645 6b971204b64349bfbb80df3cdedbb4e9 146 Pfam PF06103 Bacterial protein of unknown function (DUF948) 6 86 6.0E-12 T 10-11-2016 IPR009293 Uncharacterised protein family UPF0478 A4G23_RS14115 fe7671b0a2b612e725af764432fbe780 272 SUPERFAMILY SSF54593 145 256 1.13E-20 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS14115 fe7671b0a2b612e725af764432fbe780 272 SUPERFAMILY SSF54593 17 131 4.3E-17 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS14115 fe7671b0a2b612e725af764432fbe780 272 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 16 124 1.4E-5 T 10-11-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4G23_RS14115 fe7671b0a2b612e725af764432fbe780 272 Gene3D G3DSA:3.10.180.10 10 131 1.2E-30 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS14115 fe7671b0a2b612e725af764432fbe780 272 Gene3D G3DSA:3.10.180.10 145 257 3.1E-28 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS26405 7198a1171cd79245aea95e2c994226dc 265 Gene3D G3DSA:3.40.225.10 31 240 9.8E-54 T 10-11-2016 IPR001303 Class II aldolase/adducin N-terminal A4G23_RS26405 7198a1171cd79245aea95e2c994226dc 265 SMART SM01007 33 211 9.9E-48 T 10-11-2016 IPR001303 Class II aldolase/adducin N-terminal A4G23_RS26405 7198a1171cd79245aea95e2c994226dc 265 SUPERFAMILY SSF53639 30 242 1.51E-63 T 10-11-2016 IPR001303 Class II aldolase/adducin N-terminal A4G23_RS26405 7198a1171cd79245aea95e2c994226dc 265 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 33 211 1.3E-38 T 10-11-2016 IPR001303 Class II aldolase/adducin N-terminal A4G23_RS25055 42d3ed4966d5436afd8da7aff7f436e7 121 Gene3D G3DSA:2.40.260.10 15 100 3.1E-7 T 10-11-2016 IPR023365 Sortase domain A4G23_RS25055 42d3ed4966d5436afd8da7aff7f436e7 121 Pfam PF04203 Sortase family 9 118 2.1E-14 T 10-11-2016 IPR005754 Sortase family A4G23_RS25055 42d3ed4966d5436afd8da7aff7f436e7 121 SUPERFAMILY SSF63817 10 118 1.57E-13 T 10-11-2016 IPR023365 Sortase domain A4G23_RS27035 27229d251efc6cc8abdc06951ac7b9ef 243 SUPERFAMILY SSF52317 10 212 3.15E-26 T 10-11-2016 IPR029062 Class I glutamine amidotransferase-like A4G23_RS27035 27229d251efc6cc8abdc06951ac7b9ef 243 Gene3D G3DSA:3.40.50.880 10 207 2.0E-50 T 10-11-2016 IPR029062 Class I glutamine amidotransferase-like A4G23_RS27035 27229d251efc6cc8abdc06951ac7b9ef 243 Pfam PF03575 Peptidase family S51 12 206 6.4E-41 T 10-11-2016 IPR005320 Peptidase S51 GO:0006508|GO:0008236 A4G23_RS07070 70c9b30e619a6861b4025942fe46effc 64 Pfam PF04149 Domain of unknown function (DUF397) 10 59 3.2E-22 T 10-11-2016 IPR007278 Domain of unknown function DUF397 A4G23_RS12935 baf5b7fe77b24e13964c80c9881a54ff 475 Pfam PF07730 Histidine kinase 212 280 9.6E-14 T 10-11-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4G23_RS17525 adc1c1c769e0b24abe9cd7a41d6585df 224 PIRSF PIRSF006324 1 223 3.5E-52 T 10-11-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 A4G23_RS17525 adc1c1c769e0b24abe9cd7a41d6585df 224 Pfam PF01810 LysE type translocator 16 221 6.1E-43 T 10-11-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 A4G23_RS06780 df48baf96455070b31abd2373f75a069 120 Pfam PF03960 ArsC family 54 115 3.5E-11 T 10-11-2016 IPR006660 Arsenate reductase-like A4G23_RS06780 df48baf96455070b31abd2373f75a069 120 Gene3D G3DSA:3.40.30.10 1 118 8.7E-39 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS06780 df48baf96455070b31abd2373f75a069 120 SUPERFAMILY SSF52833 2 118 9.66E-28 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS00185 507b4b1555db381c75244f0717b3b285 250 SUPERFAMILY SSF54593 3 126 9.58E-13 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS00185 507b4b1555db381c75244f0717b3b285 250 SUPERFAMILY SSF54593 137 247 5.2E-11 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS00185 507b4b1555db381c75244f0717b3b285 250 Gene3D G3DSA:3.10.180.10 4 123 1.4E-11 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS00185 507b4b1555db381c75244f0717b3b285 250 Gene3D G3DSA:3.10.180.10 136 246 1.2E-8 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS13375 c201cf9174fc5f4a3ae9db26ac214364 85 Hamap MF_00631 Cell division protein CrgA [crgA]. 1 85 20.421 T 10-11-2016 IPR009619 Cell division protein CrgA A4G23_RS13375 c201cf9174fc5f4a3ae9db26ac214364 85 Pfam PF06781 Uncharacterised protein family (UPF0233) 2 85 5.1E-28 T 10-11-2016 IPR009619 Cell division protein CrgA A4G23_RS09135 486e233499217515d0e89b7e227f0b3a 127 SUPERFAMILY SSF54593 3 123 5.77E-21 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS09135 486e233499217515d0e89b7e227f0b3a 127 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 118 1.9E-7 T 10-11-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4G23_RS09135 486e233499217515d0e89b7e227f0b3a 127 Gene3D G3DSA:3.10.180.10 4 124 9.6E-23 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS05855 a54c8620dea263099a4503429130fd36 277 Pfam PF13803 Domain of unknown function (DUF4184) 1 264 7.5E-49 T 10-11-2016 IPR025238 Protein of unknown function DUF4184 A4G23_RS07305 e2dc6952aae2f0959dcfd09bfba5ec1b 185 Pfam PF10901 Protein of unknown function (DUF2690) 71 153 1.2E-13 T 10-11-2016 IPR021224 Protein of unknown function DUF2690 A4G23_RS02895 2ffc874205ac857e107b1e18ef908141 281 SUPERFAMILY SSF53335 27 231 1.69E-28 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS02895 2ffc874205ac857e107b1e18ef908141 281 Gene3D G3DSA:3.40.50.150 16 267 3.5E-69 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS04675 31956e75b42130b48461caad98c7d92c 249 Gene3D G3DSA:1.10.10.10 12 83 2.3E-20 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS04675 31956e75b42130b48461caad98c7d92c 249 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 54 4.9E-7 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS04675 31956e75b42130b48461caad98c7d92c 249 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 70 4.9E-7 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS04675 31956e75b42130b48461caad98c7d92c 249 Pfam PF07702 UTRA domain 107 240 2.2E-23 T 10-11-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A4G23_RS04675 31956e75b42130b48461caad98c7d92c 249 SUPERFAMILY SSF46785 13 84 2.23E-17 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS04675 31956e75b42130b48461caad98c7d92c 249 Gene3D G3DSA:3.40.1410.10 93 245 1.8E-29 T 10-11-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain A4G23_RS04675 31956e75b42130b48461caad98c7d92c 249 SMART SM00866 101 241 3.9E-14 T 10-11-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A4G23_RS04675 31956e75b42130b48461caad98c7d92c 249 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 80 2.2E-15 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS04675 31956e75b42130b48461caad98c7d92c 249 SUPERFAMILY SSF64288 68 246 1.1E-31 T 10-11-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain A4G23_RS04675 31956e75b42130b48461caad98c7d92c 249 SMART SM00345 21 80 5.9E-11 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS25020 51e1fec628b931805f1933aee6b0ef80 86 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 4 84 1.5E-14 T 10-11-2016 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 A4G23_RS09795 44199c7cd47fdab4e282773aa70b820a 413 Pfam PF09594 Protein of unknown function (DUF2029) 64 306 2.2E-8 T 10-11-2016 IPR018584 Glycosyltransferase family 87 GO:0016758 A4G23_RS08160 9e3fb67a85ad3eb172869a38c2c36676 501 Pfam PF13579 Glycosyl transferase 4-like domain 28 232 2.9E-14 T 10-11-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A4G23_RS08160 9e3fb67a85ad3eb172869a38c2c36676 501 Pfam PF13692 Glycosyl transferases group 1 306 457 2.6E-7 T 10-11-2016 A4G23_RS08160 9e3fb67a85ad3eb172869a38c2c36676 501 SUPERFAMILY SSF53756 17 247 1.44E-26 T 10-11-2016 A4G23_RS08160 9e3fb67a85ad3eb172869a38c2c36676 501 SUPERFAMILY SSF53756 288 496 1.44E-26 T 10-11-2016 A4G23_RS13485 196c630b7df2d359cec1daa597e81d99 407 Pfam PF02096 60Kd inner membrane protein 38 255 1.3E-58 T 10-11-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 A4G23_RS13485 196c630b7df2d359cec1daa597e81d99 407 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 38 255 3.2E-64 T 10-11-2016 IPR028055 Membrane insertase YidC/Oxa1, C-terminal A4G23_RS13335 5a929e064393e8d1e68136844d6ec956 496 SMART SM00332 2 235 6.9E-30 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS13335 5a929e064393e8d1e68136844d6ec956 496 SMART SM00331 11 237 2.1E-43 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS13335 5a929e064393e8d1e68136844d6ec956 496 Pfam PF00481 Protein phosphatase 2C 22 229 1.1E-10 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS13335 5a929e064393e8d1e68136844d6ec956 496 Gene3D G3DSA:3.60.40.10 2 237 2.0E-74 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS13335 5a929e064393e8d1e68136844d6ec956 496 SUPERFAMILY SSF81606 4 236 1.83E-66 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS02330 725f594df74c4710e4b18e728a7c4a5f 353 Pfam PF00483 Nucleotidyl transferase 2 235 8.3E-50 T 10-11-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A4G23_RS02330 725f594df74c4710e4b18e728a7c4a5f 353 SUPERFAMILY SSF53448 2 288 1.85E-75 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS02330 725f594df74c4710e4b18e728a7c4a5f 353 Gene3D G3DSA:3.90.550.10 2 303 6.4E-76 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS02330 725f594df74c4710e4b18e728a7c4a5f 353 TIGRFAM TIGR01208 rmlA_long: glucose-1-phosphate thymidylyltransferase 2 352 9.8E-130 T 10-11-2016 IPR005908 Glucose-1-phosphate thymidylyltransferase, long form A4G23_RS25460 6266abb206b3013256f404e0dbbfe641 135 Pfam PF07784 Protein of unknown function (DUF1622) 33 111 2.4E-27 T 10-11-2016 IPR012427 Protein of unknown function DUF1622 A4G23_RS03335 b50cb744d1269c7e62af9ec9f42d6d4c 199 Gene3D G3DSA:3.40.50.300 17 174 4.8E-18 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS03335 b50cb744d1269c7e62af9ec9f42d6d4c 199 SUPERFAMILY SSF52540 19 169 5.41E-15 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS21450 1d0c691bab0445b0f4d453057d75a4de 401 SUPERFAMILY SSF53649 58 397 6.15E-61 T 10-11-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 A4G23_RS21450 1d0c691bab0445b0f4d453057d75a4de 401 Gene3D G3DSA:3.40.720.10 37 333 7.6E-48 T 10-11-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 A4G23_RS21450 1d0c691bab0445b0f4d453057d75a4de 401 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 63 386 9.6E-44 T 10-11-2016 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 A4G23_RS20105 1f7cf01e5fed50f252a75f6024182e61 343 Pfam PF00248 Aldo/keto reductase family 16 334 7.9E-56 T 10-11-2016 IPR023210 NADP-dependent oxidoreductase domain A4G23_RS20105 1f7cf01e5fed50f252a75f6024182e61 343 SUPERFAMILY SSF51430 2 335 7.86E-84 T 10-11-2016 IPR023210 NADP-dependent oxidoreductase domain A4G23_RS20105 1f7cf01e5fed50f252a75f6024182e61 343 Gene3D G3DSA:3.20.20.100 2 335 6.4E-108 T 10-11-2016 IPR023210 NADP-dependent oxidoreductase domain A4G23_RS03025 be83a0fd3adbe020ff5a8a670badbe39 506 PIRSF PIRSF012666 1 497 6.8E-215 T 10-11-2016 IPR016602 Uncharacterised conserved protein UCP012666 A4G23_RS03025 be83a0fd3adbe020ff5a8a670badbe39 506 SUPERFAMILY SSF55931 36 464 4.02E-48 T 10-11-2016 A4G23_RS03025 be83a0fd3adbe020ff5a8a670badbe39 506 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 188 254 2.4E-5 T 10-11-2016 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 A4G23_RS00990 a9e72d64da31872e00d54ddb2fa6d62b 215 SUPERFAMILY SSF81301 32 166 9.81E-16 T 10-11-2016 A4G23_RS00990 a9e72d64da31872e00d54ddb2fa6d62b 215 Pfam PF14907 Uncharacterised nucleotidyltransferase 30 191 8.3E-9 T 10-11-2016 A4G23_RS04900 d56d63fba2c357343a173f4ddf04b2ee 341 Gene3D G3DSA:3.40.50.300 87 338 3.1E-68 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS04900 d56d63fba2c357343a173f4ddf04b2ee 341 Pfam PF13614 AAA domain 87 262 4.5E-62 T 10-11-2016 IPR025669 AAA domain A4G23_RS04900 d56d63fba2c357343a173f4ddf04b2ee 341 SUPERFAMILY SSF52540 86 338 3.4E-65 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS20615 70ac73fd1a0c314958bb8cc44f2e2b39 365 Gene3D G3DSA:3.40.190.10 295 359 1.1E-22 T 10-11-2016 A4G23_RS20615 70ac73fd1a0c314958bb8cc44f2e2b39 365 Gene3D G3DSA:3.40.190.10 5 139 1.1E-22 T 10-11-2016 A4G23_RS20615 70ac73fd1a0c314958bb8cc44f2e2b39 365 SUPERFAMILY SSF53850 38 360 1.19E-50 T 10-11-2016 A4G23_RS20615 70ac73fd1a0c314958bb8cc44f2e2b39 365 Gene3D G3DSA:3.40.190.10 144 294 1.7E-18 T 10-11-2016 A4G23_RS20615 70ac73fd1a0c314958bb8cc44f2e2b39 365 TIGRFAM TIGR01254 sfuA: ABC transporter periplasmic binding protein, thiB subfamily 41 359 1.9E-63 T 10-11-2016 IPR005948 Thiamine ABC transporter periplasmic binding protein GO:0005215|GO:0006810|GO:0015888|GO:0030288|GO:0030975 A4G23_RS20615 70ac73fd1a0c314958bb8cc44f2e2b39 365 Pfam PF13343 Bacterial extracellular solute-binding protein 91 219 1.7E-17 T 10-11-2016 A4G23_RS19615 14fe4d0ffa0ccd646afbee91c4933840 282 PIRSF PIRSF000105 1 282 8.6E-91 T 10-11-2016 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 A4G23_RS19615 14fe4d0ffa0ccd646afbee91c4933840 282 Gene3D G3DSA:1.10.1040.10 188 281 8.7E-30 T 10-11-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A4G23_RS19615 14fe4d0ffa0ccd646afbee91c4933840 282 Gene3D G3DSA:3.40.50.720 3 187 1.0E-63 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS19615 14fe4d0ffa0ccd646afbee91c4933840 282 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 186 281 7.5E-30 T 10-11-2016 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 A4G23_RS19615 14fe4d0ffa0ccd646afbee91c4933840 282 SUPERFAMILY SSF48179 186 281 6.12E-27 T 10-11-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A4G23_RS19615 14fe4d0ffa0ccd646afbee91c4933840 282 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 183 208 - T 10-11-2016 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 A4G23_RS19615 14fe4d0ffa0ccd646afbee91c4933840 282 SUPERFAMILY SSF51735 3 182 2.48E-61 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS19615 14fe4d0ffa0ccd646afbee91c4933840 282 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 4 183 6.2E-69 T 10-11-2016 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 A4G23_RS19315 8523f9a6a2b68d95a322c67521a0dc2e 240 Gene3D G3DSA:1.10.357.10 8 204 3.4E-33 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS19315 8523f9a6a2b68d95a322c67521a0dc2e 240 SUPERFAMILY SSF48498 88 189 8.9E-5 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS19315 8523f9a6a2b68d95a322c67521a0dc2e 240 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 68 1.6E-13 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS19315 8523f9a6a2b68d95a322c67521a0dc2e 240 SUPERFAMILY SSF46689 9 77 2.0E-14 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS26955 2d11478cd5b67214f90a4c674f8265a2 60 Pfam PF13822 Acyl-CoA carboxylase epsilon subunit 1 48 1.3E-5 T 10-11-2016 IPR032716 Acyl-CoA carboxylase epsilon subunit A4G23_RS16910 311993f836cd830368d1b14180afaa80 401 Pfam PF09445 RNA cap guanine-N2 methyltransferase 104 162 4.5E-8 T 10-11-2016 IPR019012 RNA cap guanine-N2 methyltransferase GO:0001510|GO:0008168|GO:0009452 Reactome: R-HSA-1368082|Reactome: R-HSA-1368108|Reactome: R-HSA-191859|Reactome: R-HSA-1989781|Reactome: R-HSA-2032785|Reactome: R-HSA-2151201|Reactome: R-HSA-2426168|Reactome: R-HSA-381340|Reactome: R-HSA-400206|Reactome: R-HSA-400253 A4G23_RS16910 311993f836cd830368d1b14180afaa80 401 Gene3D G3DSA:3.40.50.150 332 344 5.3E-19 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS16910 311993f836cd830368d1b14180afaa80 401 Gene3D G3DSA:3.40.50.150 90 176 5.3E-19 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS16910 311993f836cd830368d1b14180afaa80 401 Gene3D G3DSA:3.40.50.150 246 267 5.3E-19 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS16910 311993f836cd830368d1b14180afaa80 401 SUPERFAMILY SSF53335 70 231 1.05E-27 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS21155 09bad806df73ea97cff56703dbb9db91 261 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 2 217 8.3E-35 T 10-11-2016 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 A4G23_RS21155 09bad806df73ea97cff56703dbb9db91 261 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 200 223 3.8E-5 T 10-11-2016 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4G23_RS21155 09bad806df73ea97cff56703dbb9db91 261 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 137 160 3.8E-5 T 10-11-2016 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4G23_RS21155 09bad806df73ea97cff56703dbb9db91 261 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 40 61 3.8E-5 T 10-11-2016 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4G23_RS26875 a5290361821ce04b7815214442151cd1 348 SUPERFAMILY SSF51695 36 210 7.32E-14 T 10-11-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 A4G23_RS26875 a5290361821ce04b7815214442151cd1 348 Pfam PF16670 Phosphoinositide phospholipase C, Ca2+-dependent 55 199 2.6E-13 T 10-11-2016 IPR032075 Phosphoinositide phospholipase C, Ca2+-dependent A4G23_RS04310 6e088d0e0512399c1be4a35956060eda 503 PIRSF PIRSF018077 10 500 6.2E-216 T 10-11-2016 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 A4G23_RS04310 6e088d0e0512399c1be4a35956060eda 503 TIGRFAM TIGR03688 pupylate_PafA2: proteasome accessory factor PafA2 4 490 5.2E-246 T 10-11-2016 IPR022366 Pup deamidase GO:0008233|GO:0016811 A4G23_RS04310 6e088d0e0512399c1be4a35956060eda 503 Pfam PF03136 Pup-ligase protein 5 457 7.1E-191 T 10-11-2016 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 A4G23_RS06485 260b3d51eb1786762ed27ee043fc06a9 419 Pfam PF09594 Protein of unknown function (DUF2029) 64 312 5.9E-14 T 10-11-2016 IPR018584 Glycosyltransferase family 87 GO:0016758 A4G23_RS06485 260b3d51eb1786762ed27ee043fc06a9 419 PIRSF PIRSF010361 3 415 2.8E-79 T 10-11-2016 IPR016570 Uncharacterised conserved protein UCP010361, membrane A4G23_RS05640 82b167278dc44f5af3bfa4423acfcf21 282 Pfam PF05908 Poly-gamma-glutamate hydrolase 75 264 8.3E-33 T 10-11-2016 IPR008585 Poly-gamma-glutamate hydrolase A4G23_RS07715 94264277b78a9e3e64248655efbd458d 146 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 8 134 2.5E-25 T 10-11-2016 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like A4G23_RS07715 94264277b78a9e3e64248655efbd458d 146 Gene3D G3DSA:3.10.490.10 7 136 4.4E-27 T 10-11-2016 IPR013024 Butirosin biosynthesis, BtrG-like A4G23_RS07715 94264277b78a9e3e64248655efbd458d 146 SUPERFAMILY SSF110857 7 135 1.96E-23 T 10-11-2016 IPR013024 Butirosin biosynthesis, BtrG-like A4G23_RS25825 4e79f902ae45e45e7845235cbd3fb2dd 114 Pfam PF13581 Histidine kinase-like ATPase domain 11 106 1.0E-12 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS25825 4e79f902ae45e45e7845235cbd3fb2dd 114 Gene3D G3DSA:3.30.565.10 20 109 7.6E-6 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS25825 4e79f902ae45e45e7845235cbd3fb2dd 114 SUPERFAMILY SSF55874 13 105 1.05E-9 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS11920 78991a84d84ec679e2efe0aca3d35c21 130 Gene3D G3DSA:1.10.287.1060 6 98 7.4E-12 T 10-11-2016 A4G23_RS11920 78991a84d84ec679e2efe0aca3d35c21 130 Pfam PF06013 Proteins of 100 residues with WXG 6 89 1.0E-9 T 10-11-2016 IPR010310 Type VII secretion system ESAT-6-like A4G23_RS11920 78991a84d84ec679e2efe0aca3d35c21 130 SUPERFAMILY SSF140453 5 97 5.62E-14 T 10-11-2016 IPR010310 Type VII secretion system ESAT-6-like A4G23_RS05915 6314909e04fee065c73f3b35a38ae5a8 222 Pfam PF04402 Protein of unknown function (DUF541) 11 215 4.9E-30 T 10-11-2016 IPR007497 Protein of unknown function DUF541 A4G23_RS11955 2295a761e672d6bd44c41644a31893a5 465 SUPERFAMILY SSF103473 39 423 2.49E-49 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS11955 2295a761e672d6bd44c41644a31893a5 465 Gene3D G3DSA:1.20.1250.20 39 227 2.3E-19 T 10-11-2016 A4G23_RS11955 2295a761e672d6bd44c41644a31893a5 465 Gene3D G3DSA:1.20.1250.20 247 422 6.2E-15 T 10-11-2016 A4G23_RS11955 2295a761e672d6bd44c41644a31893a5 465 Pfam PF05977 Transmembrane secretion effector 31 421 6.5E-56 T 10-11-2016 IPR010290 Transmembrane secretion effector A4G23_RS01735 79a4ddf81e233545eae0a0034d35607d 516 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 7 491 15.137 T 10-11-2016 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 A4G23_RS01735 79a4ddf81e233545eae0a0034d35607d 516 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 62 454 2.4E-79 T 10-11-2016 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 A4G23_RS01735 79a4ddf81e233545eae0a0034d35607d 516 Pfam PF00795 Carbon-nitrogen hydrolase 221 473 3.1E-17 T 10-11-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 A4G23_RS01735 79a4ddf81e233545eae0a0034d35607d 516 Gene3D G3DSA:3.60.110.10 214 485 1.2E-38 T 10-11-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 A4G23_RS01735 79a4ddf81e233545eae0a0034d35607d 516 SUPERFAMILY SSF56317 217 486 6.15E-45 T 10-11-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 A4G23_RS22005 42e97ea2816610c34c8ea6d515723ffe 315 SUPERFAMILY SSF161098 70 298 3.66E-61 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS22005 42e97ea2816610c34c8ea6d515723ffe 315 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 308 4.9E-17 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS22005 42e97ea2816610c34c8ea6d515723ffe 315 Gene3D G3DSA:1.10.3720.10 19 298 4.7E-59 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS11675 7cf154c1405fdd0ef65c213d234814fc 208 Pfam PF00578 AhpC/TSA family 67 186 9.5E-22 T 10-11-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A4G23_RS11675 7cf154c1405fdd0ef65c213d234814fc 208 SUPERFAMILY SSF52833 67 207 1.52E-33 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS11675 7cf154c1405fdd0ef65c213d234814fc 208 Gene3D G3DSA:3.40.30.10 19 207 6.2E-42 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS17735 04efd0a423f76cdff02aca56c87d18b3 135 SUPERFAMILY SSF55874 19 123 1.28E-6 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS17735 04efd0a423f76cdff02aca56c87d18b3 135 Pfam PF13581 Histidine kinase-like ATPase domain 12 106 6.7E-10 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS10140 a9d1e540a3e611ab2085a59a598b8163 157 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 9 73 3.2E-19 T 10-11-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A4G23_RS10140 a9d1e540a3e611ab2085a59a598b8163 157 SUPERFAMILY SSF52374 7 140 1.36E-24 T 10-11-2016 A4G23_RS10140 a9d1e540a3e611ab2085a59a598b8163 157 Gene3D G3DSA:3.40.50.620 8 127 3.3E-29 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS10140 a9d1e540a3e611ab2085a59a598b8163 157 Pfam PF01467 Cytidylyltransferase-like 11 137 8.5E-16 T 10-11-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A4G23_RS11650 6dabb239eb81844c8a12754b3e72e571 192 SUPERFAMILY SSF52242 2 116 7.69E-16 T 10-11-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A4G23_RS11650 6dabb239eb81844c8a12754b3e72e571 192 Gene3D G3DSA:3.40.50.280 3 114 2.9E-14 T 10-11-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A4G23_RS11650 6dabb239eb81844c8a12754b3e72e571 192 Pfam PF02310 B12 binding domain 3 86 1.1E-8 T 10-11-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A4G23_RS13415 003d083c92a86da234b948c2c557e265 449 SMART SM00220 9 258 7.1E-40 T 10-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4G23_RS13415 003d083c92a86da234b948c2c557e265 449 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 123 135 - T 10-11-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 A4G23_RS13415 003d083c92a86da234b948c2c557e265 449 Gene3D G3DSA:1.10.510.10 101 258 2.8E-37 T 10-11-2016 A4G23_RS13415 003d083c92a86da234b948c2c557e265 449 Gene3D G3DSA:3.30.200.20 3 100 3.0E-18 T 10-11-2016 A4G23_RS13415 003d083c92a86da234b948c2c557e265 449 SUPERFAMILY SSF56112 5 263 9.04E-63 T 10-11-2016 IPR011009 Protein kinase-like domain A4G23_RS13415 003d083c92a86da234b948c2c557e265 449 SUPERFAMILY SSF56112 305 371 9.04E-63 T 10-11-2016 IPR011009 Protein kinase-like domain A4G23_RS13415 003d083c92a86da234b948c2c557e265 449 Pfam PF00069 Protein kinase domain 9 248 2.5E-38 T 10-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4G23_RS07230 04042e83927fa8c2ca313ca25ab646fa 227 Pfam PF13419 Haloacid dehalogenase-like hydrolase 20 192 1.8E-16 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS07230 04042e83927fa8c2ca313ca25ab646fa 227 Gene3D G3DSA:3.40.50.1000 78 216 7.9E-37 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS07230 04042e83927fa8c2ca313ca25ab646fa 227 Gene3D G3DSA:1.10.150.240 33 76 4.7E-6 T 10-11-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 A4G23_RS07230 04042e83927fa8c2ca313ca25ab646fa 227 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 96 192 9.1E-16 T 10-11-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A4G23_RS07230 04042e83927fa8c2ca313ca25ab646fa 227 SUPERFAMILY SSF56784 17 211 2.44E-39 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS07230 04042e83927fa8c2ca313ca25ab646fa 227 ProSitePatterns PS01228 Hypothetical cof family signature 1. 18 29 - T 10-11-2016 IPR000150 Cof protein GO:0016787 A4G23_RS26145 a4d7d6a4512d13f992ffb72bbce92fd3 284 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 268 1.7E-22 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS26145 a4d7d6a4512d13f992ffb72bbce92fd3 284 SUPERFAMILY SSF161098 74 262 1.7E-25 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS26145 a4d7d6a4512d13f992ffb72bbce92fd3 284 Gene3D G3DSA:1.10.3720.10 74 277 3.9E-23 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS15070 3b2d3cbaaf1c51ad4f2f1cdfed0cbcd1 499 Pfam PF02397 Bacterial sugar transferase 313 494 9.9E-52 T 10-11-2016 IPR003362 Bacterial sugar transferase A4G23_RS15070 3b2d3cbaaf1c51ad4f2f1cdfed0cbcd1 499 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 55 498 5.5E-100 T 10-11-2016 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase A4G23_RS18805 6bedf718086918ede975d0a0d3e2cd13 205 Pfam PF01863 Protein of unknown function DUF45 113 185 1.5E-22 T 10-11-2016 IPR002725 Protein of unknown function DUF45 A4G23_RS15885 9cd0b8ff8f37f096bdbe754660f974da 189 SUPERFAMILY SSF52980 16 152 2.14E-15 T 10-11-2016 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A4G23_RS15885 9cd0b8ff8f37f096bdbe754660f974da 189 Gene3D G3DSA:3.90.1570.10 13 139 5.7E-15 T 10-11-2016 IPR012296 Nuclease, putative, TT1808 A4G23_RS15885 9cd0b8ff8f37f096bdbe754660f974da 189 Pfam PF05685 Putative restriction endonuclease 16 141 5.1E-20 T 10-11-2016 IPR008538 Domain of unknown function DUF820 A4G23_RS15440 891b9f2cc5894a9f6a275aa98764a5cb 243 Pfam PF01551 Peptidase family M23 130 232 4.3E-32 T 10-11-2016 IPR016047 Peptidase M23 A4G23_RS15440 891b9f2cc5894a9f6a275aa98764a5cb 243 Gene3D G3DSA:2.70.70.10 81 237 1.4E-45 T 10-11-2016 A4G23_RS15440 891b9f2cc5894a9f6a275aa98764a5cb 243 SUPERFAMILY SSF51261 58 236 8.89E-47 T 10-11-2016 IPR011055 Duplicated hybrid motif A4G23_RS18380 15520576292a847792f3a6ae56bbe301 59 Pfam PF05036 Sporulation related domain 11 45 2.4E-4 T 10-11-2016 IPR007730 Sporulation-related domain GO:0042834 A4G23_RS11440 d3195c829f9e4da8d1d8d56b7c5b3231 204 SUPERFAMILY SSF109854 18 79 5.4E-6 T 10-11-2016 A4G23_RS04545 7665ed7dfd633df75ce54f43bcc2c624 303 Pfam PF00753 Metallo-beta-lactamase superfamily 24 207 1.8E-19 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS04545 7665ed7dfd633df75ce54f43bcc2c624 303 SMART SM00849 27 207 1.3E-25 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS04545 7665ed7dfd633df75ce54f43bcc2c624 303 SUPERFAMILY SSF56281 8 249 1.4E-54 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS04545 7665ed7dfd633df75ce54f43bcc2c624 303 Gene3D G3DSA:3.60.15.10 5 228 3.9E-51 T 10-11-2016 IPR001279 Metallo-beta-lactamase A4G23_RS02385 70130c258430dd9c1f81987c177a6752 149 Pfam PF01047 MarR family 36 95 1.8E-10 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS02385 70130c258430dd9c1f81987c177a6752 149 Gene3D G3DSA:1.10.10.10 7 142 2.0E-33 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS02385 70130c258430dd9c1f81987c177a6752 149 SUPERFAMILY SSF46785 9 143 1.54E-29 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS02385 70130c258430dd9c1f81987c177a6752 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 120 140 6.5E-10 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS02385 70130c258430dd9c1f81987c177a6752 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 71 86 6.5E-10 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS02385 70130c258430dd9c1f81987c177a6752 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 90 106 6.5E-10 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS02385 70130c258430dd9c1f81987c177a6752 149 SMART SM00347 27 130 2.8E-19 T 10-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4G23_RS04260 9d5a9f7a31629055684156141e2016c2 328 Pfam PF13280 WYL domain 158 324 1.8E-30 T 10-11-2016 IPR026881 WYL domain A4G23_RS18000 95a4d372b764985ecf83f3fbdb9aff29 205 Pfam PF00293 NUDIX domain 4 87 1.6E-9 T 10-11-2016 IPR000086 NUDIX hydrolase domain GO:0016787 A4G23_RS18000 95a4d372b764985ecf83f3fbdb9aff29 205 SUPERFAMILY SSF46785 117 187 4.49E-17 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS18000 95a4d372b764985ecf83f3fbdb9aff29 205 Gene3D G3DSA:3.90.79.10 3 123 1.4E-28 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS18000 95a4d372b764985ecf83f3fbdb9aff29 205 SUPERFAMILY SSF55811 3 113 2.71E-19 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS18000 95a4d372b764985ecf83f3fbdb9aff29 205 Gene3D G3DSA:1.10.10.10 124 182 3.7E-24 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS17710 051fd337981c16b06b5ca43ee13dbc68 118 SUPERFAMILY SSF49695 34 112 1.42E-6 T 10-11-2016 IPR011024 Gamma-crystallin-related A4G23_RS17710 051fd337981c16b06b5ca43ee13dbc68 118 Pfam PF03995 Peptidase inhibitor family I36 38 97 2.8E-6 T 10-11-2016 A4G23_RS17710 051fd337981c16b06b5ca43ee13dbc68 118 Gene3D G3DSA:2.60.20.10 42 100 3.5E-6 T 10-11-2016 A4G23_RS11125 59c7eae3ee0abd0bf8acab8825d82fa6 350 SUPERFAMILY SSF53807 52 344 4.32E-37 T 10-11-2016 A4G23_RS11125 59c7eae3ee0abd0bf8acab8825d82fa6 350 Pfam PF01497 Periplasmic binding protein 55 320 1.1E-19 T 10-11-2016 IPR002491 ABC transporter periplasmic binding domain GO:0005488 A4G23_RS11125 59c7eae3ee0abd0bf8acab8825d82fa6 350 Gene3D G3DSA:3.40.50.1980 203 345 3.7E-26 T 10-11-2016 A4G23_RS11125 59c7eae3ee0abd0bf8acab8825d82fa6 350 Gene3D G3DSA:3.40.50.1980 52 195 1.7E-8 T 10-11-2016 A4G23_RS26925 27dd50cc4ba244807659a2575e7cb2e7 147 SUPERFAMILY SSF55399 41 147 1.31E-39 T 10-11-2016 IPR023549 Subtilisin inhibitor GO:0004867 A4G23_RS26925 27dd50cc4ba244807659a2575e7cb2e7 147 Pfam PF00720 Subtilisin inhibitor-like 42 133 6.6E-37 T 10-11-2016 IPR023549 Subtilisin inhibitor GO:0004867 A4G23_RS26925 27dd50cc4ba244807659a2575e7cb2e7 147 PRINTS PR00294 Streptomyces subtilisin inhibitor signature 43 69 3.5E-25 T 10-11-2016 IPR000691 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor GO:0004867 A4G23_RS26925 27dd50cc4ba244807659a2575e7cb2e7 147 PRINTS PR00294 Streptomyces subtilisin inhibitor signature 122 138 3.5E-25 T 10-11-2016 IPR000691 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor GO:0004867 A4G23_RS26925 27dd50cc4ba244807659a2575e7cb2e7 147 PRINTS PR00294 Streptomyces subtilisin inhibitor signature 105 121 3.5E-25 T 10-11-2016 IPR000691 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor GO:0004867 A4G23_RS26925 27dd50cc4ba244807659a2575e7cb2e7 147 Gene3D G3DSA:3.30.350.10 42 147 7.2E-37 T 10-11-2016 IPR023549 Subtilisin inhibitor GO:0004867 A4G23_RS26925 27dd50cc4ba244807659a2575e7cb2e7 147 Hamap MF_00778 Probable subtilase-type protease inhibitor [sti]. 41 147 31.588 T 10-11-2016 IPR000691 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor GO:0004867 A4G23_RS26925 27dd50cc4ba244807659a2575e7cb2e7 147 ProDom PD004028 INHIBITOR PROTEASE SERINE DIRECT SEQUENCING SUBTILISIN PRECURSOR SIGNAL INHIBITOR-LIKE INHIBITOR 46 137 7.0E-48 T 10-11-2016 IPR023549 Subtilisin inhibitor GO:0004867 A4G23_RS26925 27dd50cc4ba244807659a2575e7cb2e7 147 ProSitePatterns PS00999 Streptomyces subtilisin-type inhibitors signature. 69 87 - T 10-11-2016 IPR020054 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor, conserved site GO:0004867 A4G23_RS21290 3296bfaea04399248ab8f87da1f419d0 167 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 144 3.7E-45 T 10-11-2016 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 A4G23_RS21290 3296bfaea04399248ab8f87da1f419d0 167 Pfam PF03477 ATP cone domain 47 132 7.1E-14 T 10-11-2016 IPR005144 ATP-cone domain Reactome: R-HSA-499943 A4G23_RS21290 3296bfaea04399248ab8f87da1f419d0 167 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 150 77.088 T 10-11-2016 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 A4G23_RS25185 6da7d1ee128f8c6cf1624fb364bc5c6b 531 Gene3D G3DSA:3.40.50.1820 201 325 4.8E-54 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS25185 6da7d1ee128f8c6cf1624fb364bc5c6b 531 Gene3D G3DSA:3.40.50.1820 401 519 4.8E-54 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS25185 6da7d1ee128f8c6cf1624fb364bc5c6b 531 Gene3D G3DSA:3.40.50.1820 61 148 4.8E-54 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS25185 6da7d1ee128f8c6cf1624fb364bc5c6b 531 SUPERFAMILY SSF53474 203 257 8.82E-21 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS25185 6da7d1ee128f8c6cf1624fb364bc5c6b 531 SUPERFAMILY SSF53474 411 519 8.82E-21 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS25185 6da7d1ee128f8c6cf1624fb364bc5c6b 531 SUPERFAMILY SSF53474 94 149 8.82E-21 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS25185 6da7d1ee128f8c6cf1624fb364bc5c6b 531 Pfam PF00561 alpha/beta hydrolase fold 97 504 1.6E-37 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS17750 d3d6cdeb5c60b98d27d8b2cdecf783d6 292 SMART SM00530 39 94 1.3E-4 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS17750 d3d6cdeb5c60b98d27d8b2cdecf783d6 292 Pfam PF13560 Helix-turn-helix domain 37 90 7.7E-11 T 10-11-2016 A4G23_RS17750 d3d6cdeb5c60b98d27d8b2cdecf783d6 292 Gene3D G3DSA:1.10.260.40 35 87 4.2E-7 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS17750 d3d6cdeb5c60b98d27d8b2cdecf783d6 292 SUPERFAMILY SSF47413 34 87 1.19E-6 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS20900 6211de989d585c18baf81f1dcccb8ca9 98 Gene3D G3DSA:3.30.70.1120 1 96 1.4E-37 T 10-11-2016 IPR007546 Protein of unknown function DUF503 A4G23_RS20900 6211de989d585c18baf81f1dcccb8ca9 98 SUPERFAMILY SSF103007 1 93 2.88E-31 T 10-11-2016 IPR007546 Protein of unknown function DUF503 A4G23_RS20900 6211de989d585c18baf81f1dcccb8ca9 98 Pfam PF04456 Protein of unknown function (DUF503) 3 89 5.9E-33 T 10-11-2016 IPR007546 Protein of unknown function DUF503 A4G23_RS05280 7358ce44fe1a6a970b40d773ca6174db 437 Pfam PF01384 Phosphate transporter family 170 321 2.3E-44 T 10-11-2016 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 A4G23_RS05280 7358ce44fe1a6a970b40d773ca6174db 437 Pfam PF01384 Phosphate transporter family 22 159 2.1E-32 T 10-11-2016 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 A4G23_RS23760 fa1eb68c2aacff5bd0e1d9ec9ebeae42 255 Pfam PF02665 Nitrate reductase gamma subunit 20 238 7.1E-89 T 10-11-2016 IPR023234 NarG-like domain A4G23_RS23760 fa1eb68c2aacff5bd0e1d9ec9ebeae42 255 Gene3D G3DSA:1.20.950.20 19 230 3.9E-76 T 10-11-2016 A4G23_RS23760 fa1eb68c2aacff5bd0e1d9ec9ebeae42 255 SUPERFAMILY SSF103501 18 238 6.28E-69 T 10-11-2016 IPR023234 NarG-like domain A4G23_RS23760 fa1eb68c2aacff5bd0e1d9ec9ebeae42 255 TIGRFAM TIGR00351 narI: respiratory nitrate reductase, gamma subunit 18 238 2.6E-61 T 10-11-2016 IPR003816 Nitrate reductase, gamma subunit GO:0008940|GO:0009325|GO:0055114 KEGG: 00910+1.7.99.4 A4G23_RS24885 6053ac3b6c41b7df5e3388bdb29a14be 266 SMART SM00382 72 246 4.2E-15 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS24885 6053ac3b6c41b7df5e3388bdb29a14be 266 SUPERFAMILY SSF52540 57 259 3.85E-42 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS24885 6053ac3b6c41b7df5e3388bdb29a14be 266 Gene3D G3DSA:3.40.50.300 58 261 2.9E-43 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS24885 6053ac3b6c41b7df5e3388bdb29a14be 266 Pfam PF00005 ABC transporter 64 197 2.4E-16 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS09210 10d680d35a8aa71905382c892fe7f2d5 446 Pfam PF13245 Part of AAA domain 23 83 1.3E-10 T 10-11-2016 A4G23_RS09210 10d680d35a8aa71905382c892fe7f2d5 446 Gene3D G3DSA:3.40.50.300 29 230 1.1E-16 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS09210 10d680d35a8aa71905382c892fe7f2d5 446 SUPERFAMILY SSF52540 32 397 4.66E-22 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS03520 ad8b0d8c8745bbe94d433c92f2aa1695 90 Gene3D G3DSA:3.90.940.10 11 86 4.4E-34 T 10-11-2016 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 A4G23_RS03520 ad8b0d8c8745bbe94d433c92f2aa1695 90 SMART SM01409 18 82 2.2E-14 T 10-11-2016 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 A4G23_RS03520 ad8b0d8c8745bbe94d433c92f2aa1695 90 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 11 83 14.945 T 10-11-2016 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4G23_RS03520 ad8b0d8c8745bbe94d433c92f2aa1695 90 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 12 80 8.5E-22 T 10-11-2016 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4G23_RS03520 ad8b0d8c8745bbe94d433c92f2aa1695 90 SUPERFAMILY SSF63562 11 86 1.26E-24 T 10-11-2016 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 A4G23_RS03520 ad8b0d8c8745bbe94d433c92f2aa1695 90 Pfam PF01192 RNA polymerase Rpb6 18 80 9.7E-15 T 10-11-2016 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 A4G23_RS22485 b0708346e3ade637e4e18c377010d327 252 SUPERFAMILY SSF51366 4 246 1.33E-38 T 10-11-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 A4G23_RS22485 b0708346e3ade637e4e18c377010d327 252 Gene3D G3DSA:3.20.20.70 4 245 4.6E-44 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS22485 b0708346e3ade637e4e18c377010d327 252 Pfam PF00977 Histidine biosynthesis protein 5 232 2.2E-36 T 10-11-2016 IPR006062 Histidine biosynthesis GO:0000105 A4G23_RS09880 0add6bf7042aed3b46b9c98cfcccb12a 230 Pfam PF13559 Domain of unknown function (DUF4129) 144 211 1.5E-16 T 10-11-2016 IPR025403 Domain of unknown function DUF4129 A4G23_RS04080 dc31056ef87520d9e6cf21c3a5b7f540 438 Pfam PF02638 Glycosyl hydrolase-like 10 67 378 2.0E-85 T 10-11-2016 IPR003790 Glycosyl hydrolase-like 10 A4G23_RS04080 dc31056ef87520d9e6cf21c3a5b7f540 438 SUPERFAMILY SSF51445 67 366 6.0E-21 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS03825 e9fd53dd774f7b633ab7383f5ae5c101 155 TIGRFAM TIGR02611 TIGR02611: TIGR02611 family protein 33 150 7.1E-35 T 10-11-2016 IPR013434 Conserved hypothetical protein CHP02611 A4G23_RS03825 e9fd53dd774f7b633ab7383f5ae5c101 155 Pfam PF09656 Putative transmembrane protein (PGPGW) 55 106 2.0E-21 T 10-11-2016 IPR019099 Uncharacterised protein family PGPGW, transmembrane A4G23_RS19985 b4910f2948926da1a3dff61aca426719 334 Gene3D G3DSA:1.10.3720.10 199 326 4.6E-18 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS19985 b4910f2948926da1a3dff61aca426719 334 Gene3D G3DSA:1.10.3720.10 87 162 4.6E-18 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS19985 b4910f2948926da1a3dff61aca426719 334 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 332 5.0E-37 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS19985 b4910f2948926da1a3dff61aca426719 334 SUPERFAMILY SSF161098 88 159 3.27E-17 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS19985 b4910f2948926da1a3dff61aca426719 334 SUPERFAMILY SSF161098 196 318 3.27E-17 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS17375 7e724d91def4c571662ab5ad82373e8e 159 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 35 142 6.1E-17 T 10-11-2016 IPR000701 Succinate dehydrogenase/Fumarate reductase, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4G23_RS17375 7e724d91def4c571662ab5ad82373e8e 159 Gene3D G3DSA:1.20.950.10 32 158 5.6E-39 T 10-11-2016 A4G23_RS17375 7e724d91def4c571662ab5ad82373e8e 159 SUPERFAMILY SSF81343 34 156 8.07E-34 T 10-11-2016 A4G23_RS18885 e8376c2d9faf2ac35f8ad6cd2951f03b 138 Pfam PF01475 Ferric uptake regulator family 11 103 1.2E-24 T 10-11-2016 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 A4G23_RS18885 e8376c2d9faf2ac35f8ad6cd2951f03b 138 SUPERFAMILY SSF46785 3 133 3.22E-32 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS18885 e8376c2d9faf2ac35f8ad6cd2951f03b 138 Gene3D G3DSA:1.10.10.10 2 82 1.4E-22 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS19300 054682d3d4bcc7559f64dd80caa7f9cd 411 SUPERFAMILY SSF51905 282 357 9.07E-20 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS19300 054682d3d4bcc7559f64dd80caa7f9cd 411 SUPERFAMILY SSF51905 2 157 9.07E-20 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS19300 054682d3d4bcc7559f64dd80caa7f9cd 411 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 302 318 2.8E-6 T 10-11-2016 A4G23_RS19300 054682d3d4bcc7559f64dd80caa7f9cd 411 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 2.8E-6 T 10-11-2016 A4G23_RS19300 054682d3d4bcc7559f64dd80caa7f9cd 411 Gene3D G3DSA:3.50.50.60 274 355 9.7E-11 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS19300 054682d3d4bcc7559f64dd80caa7f9cd 411 Gene3D G3DSA:3.50.50.60 3 167 9.7E-11 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS18165 b74ce50e382b8880ea0b9d84390a32b1 345 Gene3D G3DSA:3.20.20.100 17 332 1.7E-85 T 10-11-2016 IPR023210 NADP-dependent oxidoreductase domain A4G23_RS18165 b74ce50e382b8880ea0b9d84390a32b1 345 Pfam PF00248 Aldo/keto reductase family 32 330 5.9E-67 T 10-11-2016 IPR023210 NADP-dependent oxidoreductase domain A4G23_RS18165 b74ce50e382b8880ea0b9d84390a32b1 345 SUPERFAMILY SSF51430 17 332 8.51E-89 T 10-11-2016 IPR023210 NADP-dependent oxidoreductase domain A4G23_RS15770 49ca0691d4995502502d475a4409e472 534 Pfam PF10935 Protein of unknown function (DUF2637) 16 170 1.0E-40 T 10-11-2016 IPR021235 Protein of unknown function DUF2637 A4G23_RS03460 1e6fda7a2b0457099776daae599b7338 447 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 258 442 9.4E-32 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS03460 1e6fda7a2b0457099776daae599b7338 447 SMART SM00331 229 442 2.1E-25 T 10-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 A4G23_RS14355 8c35b2a5cffbf9e7f9df0ebb1690fee1 195 SUPERFAMILY SSF52980 56 161 2.04E-19 T 10-11-2016 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A4G23_RS14355 8c35b2a5cffbf9e7f9df0ebb1690fee1 195 Gene3D G3DSA:3.40.1350.10 47 164 1.2E-23 T 10-11-2016 IPR011856 tRNA endonuclease-like domain GO:0003676|GO:0004518 Reactome: R-HSA-6784531 A4G23_RS14355 8c35b2a5cffbf9e7f9df0ebb1690fee1 195 Pfam PF04471 Restriction endonuclease 53 161 3.5E-22 T 10-11-2016 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 A4G23_RS23505 00b8b4df40ab4aab1f64f3a30c8a4c93 697 Pfam PF03176 MMPL family 45 364 5.0E-70 T 10-11-2016 IPR004869 Membrane transport protein, MMPL domain GO:0016020 A4G23_RS23505 00b8b4df40ab4aab1f64f3a30c8a4c93 697 Pfam PF03176 MMPL family 396 689 3.7E-51 T 10-11-2016 IPR004869 Membrane transport protein, MMPL domain GO:0016020 A4G23_RS23505 00b8b4df40ab4aab1f64f3a30c8a4c93 697 Gene3D G3DSA:1.20.1640.10 484 687 7.9E-23 T 10-11-2016 A4G23_RS23505 00b8b4df40ab4aab1f64f3a30c8a4c93 697 Gene3D G3DSA:1.20.1640.10 131 341 2.1E-30 T 10-11-2016 A4G23_RS23505 00b8b4df40ab4aab1f64f3a30c8a4c93 697 SUPERFAMILY SSF82866 136 335 1.57E-32 T 10-11-2016 A4G23_RS23505 00b8b4df40ab4aab1f64f3a30c8a4c93 697 SUPERFAMILY SSF82866 476 685 2.09E-28 T 10-11-2016 A4G23_RS16870 360d0f1253f0d70bf71c884243da5cb9 152 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 4 139 6.0E-26 T 10-11-2016 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 A4G23_RS16870 360d0f1253f0d70bf71c884243da5cb9 152 Gene3D G3DSA:3.40.50.300 2 147 9.1E-45 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS16870 360d0f1253f0d70bf71c884243da5cb9 152 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 2 122 8.5E-30 T 10-11-2016 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 A4G23_RS16870 360d0f1253f0d70bf71c884243da5cb9 152 SUPERFAMILY SSF52540 18 114 5.01E-13 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS11100 4cf344b7d9cb7eb5553e397dfddf45c3 891 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 620 637 1.5E-11 T 10-11-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 A4G23_RS11100 4cf344b7d9cb7eb5553e397dfddf45c3 891 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 563 574 1.5E-11 T 10-11-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 A4G23_RS11100 4cf344b7d9cb7eb5553e397dfddf45c3 891 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 647 660 1.5E-11 T 10-11-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 A4G23_RS11100 4cf344b7d9cb7eb5553e397dfddf45c3 891 SUPERFAMILY SSF56601 490 764 6.28E-35 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS11100 4cf344b7d9cb7eb5553e397dfddf45c3 891 Gene3D G3DSA:3.40.710.10 550 771 2.4E-49 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS11100 4cf344b7d9cb7eb5553e397dfddf45c3 891 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 555 763 6.9E-30 T 10-11-2016 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 A4G23_RS21145 686fd6f03280ebd2733b264e03182cc4 64 Pfam PF11248 Protein of unknown function (DUF3046) 1 61 1.8E-32 T 10-11-2016 IPR021408 Protein of unknown function DUF3046 A4G23_RS12890 e79b4f32c82e3e00c2d3d45182d70b11 267 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 21 162 4.5E-19 T 10-11-2016 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 A4G23_RS12890 e79b4f32c82e3e00c2d3d45182d70b11 267 SUPERFAMILY SSF109854 14 168 7.02E-21 T 10-11-2016 A4G23_RS12890 e79b4f32c82e3e00c2d3d45182d70b11 267 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 20 238 8.1E-25 T 10-11-2016 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type A4G23_RS12890 e79b4f32c82e3e00c2d3d45182d70b11 267 Gene3D G3DSA:1.20.120.450 11 73 2.2E-10 T 10-11-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase A4G23_RS20430 b9fd36e0276485e26e8611efdab4e499 317 SUPERFAMILY SSF55797 195 316 5.76E-24 T 10-11-2016 IPR014044 CAP domain A4G23_RS20430 b9fd36e0276485e26e8611efdab4e499 317 Gene3D G3DSA:3.40.33.10 195 311 2.3E-10 T 10-11-2016 IPR014044 CAP domain A4G23_RS20430 b9fd36e0276485e26e8611efdab4e499 317 Pfam PF00188 Cysteine-rich secretory protein family 201 315 3.9E-20 T 10-11-2016 IPR014044 CAP domain A4G23_RS17090 751875c6d7a144a802eaae64889756ee 377 Pfam PF00756 Putative esterase 131 354 5.9E-14 T 10-11-2016 IPR000801 Putative esterase Reactome: R-HSA-156590 A4G23_RS17090 751875c6d7a144a802eaae64889756ee 377 Gene3D G3DSA:3.40.50.1820 102 365 8.6E-41 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS17090 751875c6d7a144a802eaae64889756ee 377 SUPERFAMILY SSF53474 110 365 8.11E-31 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS27245 f7e1886453b2c43281f2a4c03b4d8a38 198 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 180 4.3E-51 T 10-11-2016 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 A4G23_RS27245 f7e1886453b2c43281f2a4c03b4d8a38 198 SUPERFAMILY SSF52016 2 188 8.63E-49 T 10-11-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel A4G23_RS27245 f7e1886453b2c43281f2a4c03b4d8a38 198 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 191 36.59 T 10-11-2016 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 A4G23_RS27245 f7e1886453b2c43281f2a4c03b4d8a38 198 Pfam PF00694 Aconitase C-terminal domain 1 116 5.7E-24 T 10-11-2016 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 A4G23_RS27245 f7e1886453b2c43281f2a4c03b4d8a38 198 Gene3D G3DSA:3.20.19.10 2 187 1.7E-36 T 10-11-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel A4G23_RS09000 45d0ed6976670cdc308d6853ddbd0603 424 SUPERFAMILY SSF51905 3 248 1.98E-21 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS09000 45d0ed6976670cdc308d6853ddbd0603 424 Gene3D G3DSA:3.50.50.60 86 222 6.6E-20 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS09000 45d0ed6976670cdc308d6853ddbd0603 424 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 4 337 1.0E-125 T 10-11-2016 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase A4G23_RS04235 bf0defd55868d09cc0a4a934e82bf7a7 314 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 18 243 1.3E-57 T 10-11-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A4G23_RS04235 bf0defd55868d09cc0a4a934e82bf7a7 314 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 17 44 2.7E-34 T 10-11-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A4G23_RS04235 bf0defd55868d09cc0a4a934e82bf7a7 314 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 171 199 2.7E-34 T 10-11-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A4G23_RS04235 bf0defd55868d09cc0a4a934e82bf7a7 314 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 103 121 2.7E-34 T 10-11-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A4G23_RS04235 bf0defd55868d09cc0a4a934e82bf7a7 314 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 121 147 2.7E-34 T 10-11-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A4G23_RS04235 bf0defd55868d09cc0a4a934e82bf7a7 314 Pfam PF00902 Sec-independent protein translocase protein (TatC) 20 238 1.9E-57 T 10-11-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A4G23_RS04235 bf0defd55868d09cc0a4a934e82bf7a7 314 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 12 257 16.845 T 10-11-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A4G23_RS21510 5a6915eb68410683f6d18417d303acd8 98 Pfam PF13834 Domain of unknown function (DUF4193) 1 97 3.4E-45 T 10-11-2016 IPR025242 Protein of unknown function DUF4193 A4G23_RS21835 98e29fddf688aeb6679a14214705f247 307 Gene3D G3DSA:1.10.260.40 51 103 5.8E-11 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS21835 98e29fddf688aeb6679a14214705f247 307 Pfam PF13560 Helix-turn-helix domain 50 106 4.5E-14 T 10-11-2016 A4G23_RS21835 98e29fddf688aeb6679a14214705f247 307 SMART SM00530 54 109 2.8E-8 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS21835 98e29fddf688aeb6679a14214705f247 307 SUPERFAMILY SSF47413 49 103 1.9E-9 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS22350 eecffb4eb89c933a0796aa483929449e 1541 SUPERFAMILY SSF52540 259 321 5.6E-6 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS22350 eecffb4eb89c933a0796aa483929449e 1541 SUPERFAMILY SSF52540 352 426 5.6E-6 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS22650 975334ce887daa26e608bb5e9ab0441b 139 Pfam PF07681 DoxX 4 85 1.1E-10 T 10-11-2016 IPR032808 DoxX family A4G23_RS23810 00d1d72126f2e9ca71c6b45d1024d838 442 PRINTS PR00723 Subtilisin serine protease family (S8) signature 215 228 3.1E-12 T 10-11-2016 IPR015500 Peptidase S8, subtilisin-related A4G23_RS23810 00d1d72126f2e9ca71c6b45d1024d838 442 PRINTS PR00723 Subtilisin serine protease family (S8) signature 373 389 3.1E-12 T 10-11-2016 IPR015500 Peptidase S8, subtilisin-related A4G23_RS23810 00d1d72126f2e9ca71c6b45d1024d838 442 PRINTS PR00723 Subtilisin serine protease family (S8) signature 175 194 3.1E-12 T 10-11-2016 IPR015500 Peptidase S8, subtilisin-related A4G23_RS23810 00d1d72126f2e9ca71c6b45d1024d838 442 Gene3D G3DSA:3.30.70.80 61 114 7.3E-5 T 10-11-2016 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 A4G23_RS23810 00d1d72126f2e9ca71c6b45d1024d838 442 SUPERFAMILY SSF52743 149 411 3.01E-57 T 10-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4G23_RS23810 00d1d72126f2e9ca71c6b45d1024d838 442 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 180 191 - T 10-11-2016 IPR023827 Peptidase S8, subtilisin, Asp-active site A4G23_RS23810 00d1d72126f2e9ca71c6b45d1024d838 442 Gene3D G3DSA:3.40.50.200 151 413 6.4E-61 T 10-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4G23_RS23810 00d1d72126f2e9ca71c6b45d1024d838 442 Pfam PF00082 Subtilase family 175 410 7.6E-25 T 10-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A4G23_RS20775 a59a52881dfb4d62e8d1ef4658cff2ea 244 SUPERFAMILY SSF51412 15 191 2.29E-5 T 10-11-2016 A4G23_RS20775 a59a52881dfb4d62e8d1ef4658cff2ea 244 Gene3D G3DSA:3.20.20.70 1 238 2.1E-41 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS20775 a59a52881dfb4d62e8d1ef4658cff2ea 244 Pfam PF05853 beta-keto acid cleavage enzyme 1 238 4.3E-29 T 10-11-2016 IPR008567 3-keto-5-aminohexanoate cleavage enzyme GO:0016740|GO:0019475 KEGG: 00600+2.3.1.24 A4G23_RS07325 87baaa03d1564f95808e1090031328cb 92 Pfam PF09860 Uncharacterized protein conserved in bacteria (DUF2087) 19 88 7.0E-26 T 10-11-2016 IPR018656 Domain of unknown function DUF2087 A4G23_RS01285 c15792f253cf7af99bafc541e14c71be 216 Pfam PF03029 Conserved hypothetical ATP binding protein 40 205 1.2E-23 T 10-11-2016 IPR004130 GPN-loop GTPase A4G23_RS01285 c15792f253cf7af99bafc541e14c71be 216 Gene3D G3DSA:3.40.50.300 31 207 3.2E-15 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS01285 c15792f253cf7af99bafc541e14c71be 216 SUPERFAMILY SSF52540 34 206 5.15E-22 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS12720 7ff33a72367268455dfb111cd75ac877 239 Pfam PF00440 Bacterial regulatory proteins, tetR family 36 79 4.5E-13 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS12720 7ff33a72367268455dfb111cd75ac877 239 SUPERFAMILY SSF46689 22 105 1.15E-16 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS12720 7ff33a72367268455dfb111cd75ac877 239 Gene3D G3DSA:1.10.357.10 23 239 7.4E-61 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS12720 7ff33a72367268455dfb111cd75ac877 239 SUPERFAMILY SSF48498 173 237 3.56E-11 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS12720 7ff33a72367268455dfb111cd75ac877 239 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 48 7.9E-8 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS12720 7ff33a72367268455dfb111cd75ac877 239 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 55 78 7.9E-8 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS11795 9af9f36d05160c193be66f5ecc25dbc9 956 Pfam PF13625 Helicase conserved C-terminal domain 656 778 9.2E-43 T 10-11-2016 IPR032830 Helicase XPB/Ssl2, N-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 A4G23_RS06635 8f4d706caa5827b797ecc8d06e97f50b 183 Pfam PF11241 Protein of unknown function (DUF3043) 15 181 9.0E-62 T 10-11-2016 IPR021403 Protein of unknown function DUF3043 A4G23_RS19630 106ecd36782d92301089760548ac39e7 223 Pfam PF01939 Protein of unknown function DUF91 2 223 3.6E-85 T 10-11-2016 IPR002793 Endonuclease NucS A4G23_RS19630 106ecd36782d92301089760548ac39e7 223 Hamap MF_00722 Endonuclease NucS [nucS]. 1 215 31.438 T 10-11-2016 IPR002793 Endonuclease NucS A4G23_RS23940 34d8ce74aef074d7abc16fe5192aecfc 325 Gene3D G3DSA:3.40.50.2300 39 161 2.7E-27 T 10-11-2016 A4G23_RS23940 34d8ce74aef074d7abc16fe5192aecfc 325 SUPERFAMILY SSF53822 43 314 1.04E-45 T 10-11-2016 IPR028082 Periplasmic binding protein-like I A4G23_RS23940 34d8ce74aef074d7abc16fe5192aecfc 325 Pfam PF13407 Periplasmic binding protein domain 44 287 2.3E-37 T 10-11-2016 IPR025997 Periplasmic binding protein A4G23_RS23940 34d8ce74aef074d7abc16fe5192aecfc 325 Gene3D G3DSA:3.40.50.2300 162 286 3.9E-16 T 10-11-2016 A4G23_RS06525 ff6752d06c32442d35ba716447c3e44a 441 Gene3D G3DSA:3.40.640.10 41 275 5.6E-67 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS06525 ff6752d06c32442d35ba716447c3e44a 441 SUPERFAMILY SSF53383 24 421 2.2E-87 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS06525 ff6752d06c32442d35ba716447c3e44a 441 Gene3D G3DSA:3.90.1150.10 276 425 1.1E-33 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS06525 ff6752d06c32442d35ba716447c3e44a 441 Pfam PF00266 Aminotransferase class-V 25 413 1.8E-74 T 10-11-2016 IPR000192 Aminotransferase class V domain A4G23_RS14020 725ef336bdf681ee1b0d31da40a93e1e 211 Gene3D G3DSA:3.40.50.10230 6 207 6.4E-82 T 10-11-2016 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 A4G23_RS14020 725ef336bdf681ee1b0d31da40a93e1e 211 SUPERFAMILY SSF63965 7 208 6.67E-74 T 10-11-2016 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 A4G23_RS14020 725ef336bdf681ee1b0d31da40a93e1e 211 Pfam PF02570 Precorrin-8X methylmutase 15 208 2.0E-74 T 10-11-2016 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 A4G23_RS11050 8037841d092c9642601ee33f94c4eae8 108 Pfam PF08734 GYD domain 4 94 5.9E-22 T 10-11-2016 IPR014845 Uncharacterised protein GYD A4G23_RS23410 ad1887b28559c34e796a3c2ec3eb9493 347 SUPERFAMILY SSF81345 27 343 4.97E-64 T 10-11-2016 IPR029022 ABC transporter, BtuC-like A4G23_RS23410 ad1887b28559c34e796a3c2ec3eb9493 347 Gene3D G3DSA:1.10.3470.10 27 346 5.6E-77 T 10-11-2016 IPR029022 ABC transporter, BtuC-like A4G23_RS23410 ad1887b28559c34e796a3c2ec3eb9493 347 Pfam PF01032 FecCD transport family 37 343 1.8E-70 T 10-11-2016 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 A4G23_RS00370 9d50d4c0f01b56b580fb0facb7d3e871 167 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 3 151 7.7E-26 T 10-11-2016 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 A4G23_RS00370 9d50d4c0f01b56b580fb0facb7d3e871 167 SUPERFAMILY SSF56300 3 164 5.77E-34 T 10-11-2016 IPR029052 Metallo-dependent phosphatase-like A4G23_RS00370 9d50d4c0f01b56b580fb0facb7d3e871 167 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 3 151 8.3E-26 T 10-11-2016 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 A4G23_RS00370 9d50d4c0f01b56b580fb0facb7d3e871 167 Gene3D G3DSA:3.60.21.10 3 156 1.8E-31 T 10-11-2016 IPR029052 Metallo-dependent phosphatase-like A4G23_RS10630 6fe6f063542607913be17c9d2f4c9381 678 SUPERFAMILY SSF50998 311 509 7.98E-12 T 10-11-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily A4G23_RS10630 6fe6f063542607913be17c9d2f4c9381 678 SUPERFAMILY SSF50998 566 607 7.98E-12 T 10-11-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily A4G23_RS10630 6fe6f063542607913be17c9d2f4c9381 678 Gene3D G3DSA:2.140.10.10 197 214 3.8E-15 T 10-11-2016 IPR027295 Quinoprotein alcohol dehydrogenase-like domain A4G23_RS10630 6fe6f063542607913be17c9d2f4c9381 678 Gene3D G3DSA:2.140.10.10 247 602 3.8E-15 T 10-11-2016 IPR027295 Quinoprotein alcohol dehydrogenase-like domain A4G23_RS10630 6fe6f063542607913be17c9d2f4c9381 678 Pfam PF13360 PQQ-like domain 301 423 1.9E-7 T 10-11-2016 IPR002372 Pyrrolo-quinoline quinone repeat A4G23_RS10630 6fe6f063542607913be17c9d2f4c9381 678 Pfam PF13360 PQQ-like domain 454 580 3.5E-4 T 10-11-2016 IPR002372 Pyrrolo-quinoline quinone repeat A4G23_RS11345 2e2b340e67d139355d69650b8e12fa41 310 Gene3D G3DSA:3.40.50.1100 68 306 2.4E-55 T 10-11-2016 A4G23_RS11345 2e2b340e67d139355d69650b8e12fa41 310 SUPERFAMILY SSF53686 32 305 1.13E-64 T 10-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4G23_RS11345 2e2b340e67d139355d69650b8e12fa41 310 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 33 298 3.9E-59 T 10-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4G23_RS22715 2d933a057c3cf83719dfdbaf32bfe135 797 Gene3D G3DSA:3.40.50.300 153 238 1.3E-4 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS22715 2d933a057c3cf83719dfdbaf32bfe135 797 SUPERFAMILY SSF52540 239 355 1.48E-5 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS22715 2d933a057c3cf83719dfdbaf32bfe135 797 SUPERFAMILY SSF52540 152 205 1.48E-5 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS27080 e36ead6d6acabc1355beb51257d125ca 435 Pfam PF00999 Sodium/hydrogen exchanger family 14 405 1.7E-34 T 10-11-2016 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A4G23_RS12555 2543466dfe85285c5c0311af1ff25929 117 Pfam PF02583 Metal-sensitive transcriptional repressor 32 112 2.3E-30 T 10-11-2016 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 A4G23_RS11435 1dd69673a6bc48ec86c22268d1433df2 146 Pfam PF13490 Putative zinc-finger 3 33 1.1E-6 T 10-11-2016 IPR027383 Putative zinc-finger A4G23_RS23145 302bcf9a4f62ad2a71a55bd09ed6e0b8 308 SUPERFAMILY SSF102114 13 237 1.59E-14 T 10-11-2016 A4G23_RS23145 302bcf9a4f62ad2a71a55bd09ed6e0b8 308 Gene3D G3DSA:3.20.20.70 13 238 2.8E-8 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS16040 8bb6511903d565a118c374a5a7c1fda6 280 Gene3D G3DSA:3.90.1720.10 160 279 1.4E-38 T 10-11-2016 IPR000064 Endopeptidase, NLPC/P60 domain A4G23_RS16040 8bb6511903d565a118c374a5a7c1fda6 280 SUPERFAMILY SSF54001 160 279 4.9E-37 T 10-11-2016 A4G23_RS16040 8bb6511903d565a118c374a5a7c1fda6 280 Pfam PF00877 NlpC/P60 family 178 266 1.1E-20 T 10-11-2016 IPR000064 Endopeptidase, NLPC/P60 domain A4G23_RS22885 4cb190c98de974ed05367e594198a8e8 440 Pfam PF02653 Branched-chain amino acid transport system / permease component 91 424 6.9E-38 T 10-11-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 A4G23_RS07620 48313ead9ab2c106a6e1286d048be094 189 SUPERFAMILY SSF55729 7 165 8.62E-17 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS07620 48313ead9ab2c106a6e1286d048be094 189 Gene3D G3DSA:3.40.630.30 7 165 7.6E-18 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS07620 48313ead9ab2c106a6e1286d048be094 189 Pfam PF00583 Acetyltransferase (GNAT) family 69 143 5.1E-6 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS26470 c06b39eaf9a3f3fbd58161dac2ff1c42 172 Pfam PF06841 T4-like virus tail tube protein gp19 34 154 2.3E-31 T 10-11-2016 IPR010667 Bacteriophage T4, Gp19, tail tube GO:0005198 A4G23_RS26470 c06b39eaf9a3f3fbd58161dac2ff1c42 172 TIGRFAM TIGR02241 TIGR02241: conserved hypothetical phage tail region protein 3 155 2.4E-30 T 10-11-2016 IPR011747 Conserved hypothetical protein CHP02241 A4G23_RS23280 27126370717f96cc32aca4050b3cc4c3 242 Pfam PF00005 ABC transporter 33 181 4.2E-33 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS23280 27126370717f96cc32aca4050b3cc4c3 242 Gene3D G3DSA:3.40.50.300 12 234 4.4E-71 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS23280 27126370717f96cc32aca4050b3cc4c3 242 SUPERFAMILY SSF52540 13 236 1.73E-70 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS23280 27126370717f96cc32aca4050b3cc4c3 242 SMART SM00382 42 230 5.6E-15 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS23280 27126370717f96cc32aca4050b3cc4c3 242 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS14370 c6e88a2650e4e9bcf490fc5cab269754 356 SUPERFAMILY SSF53474 227 317 1.08E-39 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS14370 c6e88a2650e4e9bcf490fc5cab269754 356 SUPERFAMILY SSF53474 40 191 1.08E-39 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS14370 c6e88a2650e4e9bcf490fc5cab269754 356 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 60 240 2.0E-8 T 10-11-2016 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 A4G23_RS14370 c6e88a2650e4e9bcf490fc5cab269754 356 Gene3D G3DSA:3.40.50.1820 50 313 3.1E-37 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS18080 f10b293abb000d40741415b7440f06e9 443 Pfam PF01566 Natural resistance-associated macrophage protein 27 304 4.7E-27 T 10-11-2016 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 A4G23_RS14640 fb09669ae3bb7f19728188999e27d00f 300 Gene3D G3DSA:1.10.1040.10 185 297 3.5E-4 T 10-11-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A4G23_RS14640 fb09669ae3bb7f19728188999e27d00f 300 SUPERFAMILY SSF51735 16 163 9.47E-29 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS14640 fb09669ae3bb7f19728188999e27d00f 300 PIRSF PIRSF000103 9 300 1.2E-35 T 10-11-2016 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 A4G23_RS14640 fb09669ae3bb7f19728188999e27d00f 300 Gene3D G3DSA:3.40.50.720 11 165 6.5E-31 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS14640 fb09669ae3bb7f19728188999e27d00f 300 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 16 164 5.9E-22 T 10-11-2016 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 A4G23_RS12010 c9541ce2c34558098694d8744d853b65 149 SUPERFAMILY SSF53448 3 106 8.44E-19 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS18825 254b9e551702acc81304c18fcb7afe2c 157 Pfam PF13673 Acetyltransferase (GNAT) domain 54 138 1.5E-14 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS18825 254b9e551702acc81304c18fcb7afe2c 157 SUPERFAMILY SSF55729 8 151 1.55E-24 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS18825 254b9e551702acc81304c18fcb7afe2c 157 Gene3D G3DSA:3.40.630.30 8 152 2.8E-26 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS23325 38f611c392d879553fcf42986602ac4b 296 Pfam PF11575 FhuF 2Fe-2S C-terminal domain 260 280 5.8E-6 T 10-11-2016 IPR024726 Ferric iron reductase, C-terminal GO:0051537 A4G23_RS00620 284c5625b1100aa45a3dd41882a62a7d 66 Pfam PF14013 MT0933-like antitoxin protein 5 52 1.2E-16 T 10-11-2016 IPR028037 Antitoxin Rv0909/MT0933 A4G23_RS03615 72eafea527fc0ac16f853d9e80b3452a 394 PIRSF PIRSF001456 1 387 3.9E-127 T 10-11-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A4G23_RS03615 72eafea527fc0ac16f853d9e80b3452a 394 ProSitePatterns PS00787 Chorismate synthase signature 1. 10 25 - T 10-11-2016 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A4G23_RS03615 72eafea527fc0ac16f853d9e80b3452a 394 ProSitePatterns PS00789 Chorismate synthase signature 3. 343 359 - T 10-11-2016 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A4G23_RS03615 72eafea527fc0ac16f853d9e80b3452a 394 Hamap MF_00300 Chorismate synthase [aroC]. 4 376 34.4 T 10-11-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A4G23_RS03615 72eafea527fc0ac16f853d9e80b3452a 394 TIGRFAM TIGR00033 aroC: chorismate synthase 4 374 3.7E-141 T 10-11-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A4G23_RS03615 72eafea527fc0ac16f853d9e80b3452a 394 ProSitePatterns PS00788 Chorismate synthase signature 2. 136 152 - T 10-11-2016 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A4G23_RS03615 72eafea527fc0ac16f853d9e80b3452a 394 SUPERFAMILY SSF103263 3 391 3.14E-138 T 10-11-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A4G23_RS03615 72eafea527fc0ac16f853d9e80b3452a 394 Pfam PF01264 Chorismate synthase 4 368 1.4E-117 T 10-11-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A4G23_RS03615 72eafea527fc0ac16f853d9e80b3452a 394 Gene3D G3DSA:3.60.150.10 4 391 4.0E-155 T 10-11-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A4G23_RS09950 63ceadd901cf3a01f8bb58a0539f12b3 60 Pfam PF03966 Trm112p-like protein 7 47 1.7E-8 T 10-11-2016 IPR005651 Uncharacterised protein family UPF0434/Trm112 A4G23_RS09950 63ceadd901cf3a01f8bb58a0539f12b3 60 SUPERFAMILY SSF158997 1 58 4.84E-16 T 10-11-2016 A4G23_RS09950 63ceadd901cf3a01f8bb58a0539f12b3 60 Gene3D G3DSA:2.20.25.10 10 58 6.2E-21 T 10-11-2016 A4G23_RS11830 efaea5a33aadbf55153ab8dccfb32bd8 273 Pfam PF12679 ABC-2 family transporter protein 41 203 6.7E-7 T 10-11-2016 IPR032688 ABC-2 family transporter protein GO:0006810 A4G23_RS13545 b9b385a1d32052e20ecad9306e686dd8 786 Gene3D G3DSA:3.10.129.10 48 101 6.6E-4 T 10-11-2016 IPR029069 HotDog domain A4G23_RS08045 5ef3640f0246b42d1eee3e5b2d449a82 434 Pfam PF09594 Protein of unknown function (DUF2029) 72 334 3.5E-47 T 10-11-2016 IPR018584 Glycosyltransferase family 87 GO:0016758 A4G23_RS22965 703eea3ff670f6ae7a9c46a0fc0e2744 467 Pfam PF14257 Domain of unknown function (DUF4349) 23 288 8.2E-72 T 10-11-2016 IPR025645 Domain of unknown function DUF4349 A4G23_RS02565 f91a85e611f6d183dea91907b3db8a46 142 Gene3D G3DSA:3.30.565.10 41 138 8.7E-13 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS02565 f91a85e611f6d183dea91907b3db8a46 142 SUPERFAMILY SSF55874 30 137 1.26E-15 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS02565 f91a85e611f6d183dea91907b3db8a46 142 Pfam PF13581 Histidine kinase-like ATPase domain 11 133 2.7E-12 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS11710 cc80c55bc770efae14dc437b29bba39c 76 Pfam PF04149 Domain of unknown function (DUF397) 6 26 5.2E-8 T 10-11-2016 IPR007278 Domain of unknown function DUF397 A4G23_RS11710 cc80c55bc770efae14dc437b29bba39c 76 Pfam PF04149 Domain of unknown function (DUF397) 25 75 1.2E-19 T 10-11-2016 IPR007278 Domain of unknown function DUF397 A4G23_RS18565 f54ebfb7f37f4138c35b67b16c21c992 302 Pfam PF13490 Putative zinc-finger 15 43 3.4E-7 T 10-11-2016 IPR027383 Putative zinc-finger A4G23_RS12580 cf98c4843f659da0d7f48548ed4bbe71 333 Gene3D G3DSA:1.10.530.10 46 187 2.4E-33 T 10-11-2016 A4G23_RS12580 cf98c4843f659da0d7f48548ed4bbe71 333 Pfam PF00877 NlpC/P60 family 209 303 1.8E-23 T 10-11-2016 IPR000064 Endopeptidase, NLPC/P60 domain A4G23_RS12580 cf98c4843f659da0d7f48548ed4bbe71 333 SUPERFAMILY SSF54001 188 318 1.13E-35 T 10-11-2016 A4G23_RS12580 cf98c4843f659da0d7f48548ed4bbe71 333 Gene3D G3DSA:3.90.1720.10 190 319 1.8E-38 T 10-11-2016 IPR000064 Endopeptidase, NLPC/P60 domain A4G23_RS12580 cf98c4843f659da0d7f48548ed4bbe71 333 Pfam PF01464 Transglycosylase SLT domain 62 172 3.7E-15 T 10-11-2016 IPR008258 Transglycosylase SLT domain 1 A4G23_RS12580 cf98c4843f659da0d7f48548ed4bbe71 333 SUPERFAMILY SSF53955 45 180 2.6E-33 T 10-11-2016 IPR023346 Lysozyme-like domain A4G23_RS04525 8920a1863951003d242fd7d38cf3bee0 130 Pfam PF02656 Domain of unknown function (DUF202) 27 92 1.8E-14 T 10-11-2016 IPR003807 Domain of unknown function DUF202 A4G23_RS08335 9023aab39f257c12657c09694534d256 341 Pfam PF01757 Acyltransferase family 15 316 2.7E-16 T 10-11-2016 IPR002656 Acyltransferase 3 GO:0016747 A4G23_RS01095 a39a566f456f4ddeafbe097d1a5a3eb9 342 SUPERFAMILY SSF55869 22 82 3.79E-20 T 10-11-2016 A4G23_RS01095 a39a566f456f4ddeafbe097d1a5a3eb9 342 Gene3D G3DSA:3.90.15.10 88 214 8.8E-27 T 10-11-2016 IPR014711 DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type GO:0003677|GO:0003917|GO:0006265 A4G23_RS01095 a39a566f456f4ddeafbe097d1a5a3eb9 342 Gene3D G3DSA:1.20.120.380 234 305 2.5E-26 T 10-11-2016 IPR027362 DNA topoisomerase I catalytic fragment, domain 2 A4G23_RS01095 a39a566f456f4ddeafbe097d1a5a3eb9 342 Pfam PF01028 Eukaryotic DNA topoisomerase I, catalytic core 82 286 2.5E-26 T 10-11-2016 IPR013500 DNA topoisomerase I, catalytic core, eukaryotic-type GO:0003677|GO:0003918|GO:0006265 A4G23_RS01095 a39a566f456f4ddeafbe097d1a5a3eb9 342 SUPERFAMILY SSF56349 78 305 1.53E-55 T 10-11-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A4G23_RS19740 a040cf1cc0c6e4ffc9efa744cf945321 566 Pfam PF01642 Methylmalonyl-CoA mutase 29 558 3.5E-214 T 10-11-2016 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A4G23_RS19740 a040cf1cc0c6e4ffc9efa744cf945321 566 Gene3D G3DSA:3.20.20.240 28 560 4.5E-216 T 10-11-2016 IPR014348 Cobalamin (vitamin B12)-dependent enzyme, catalytic subdomain GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A4G23_RS19740 a040cf1cc0c6e4ffc9efa744cf945321 566 SUPERFAMILY SSF51703 7 560 8.37E-194 T 10-11-2016 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A4G23_RS19740 a040cf1cc0c6e4ffc9efa744cf945321 566 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 27 564 3.9E-201 T 10-11-2016 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A4G23_RS00695 1f60abacbb30be484cee7d2aadd8aab6 254 Pfam PF13350 Tyrosine phosphatase family 6 244 4.2E-56 T 10-11-2016 IPR026893 Tyrosine/serine-protein phosphatase IphP-type A4G23_RS00695 1f60abacbb30be484cee7d2aadd8aab6 254 SUPERFAMILY SSF52799 7 243 2.4E-45 T 10-11-2016 IPR029021 Protein-tyrosine phosphatase-like A4G23_RS00695 1f60abacbb30be484cee7d2aadd8aab6 254 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 139 149 - T 10-11-2016 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311|GO:0016791 A4G23_RS00695 1f60abacbb30be484cee7d2aadd8aab6 254 Gene3D G3DSA:3.90.190.10 8 174 6.6E-23 T 10-11-2016 IPR029021 Protein-tyrosine phosphatase-like A4G23_RS15840 0e48bb21bb84161c17208cdeb9c0127a 245 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 18 224 9.0E-48 T 10-11-2016 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 A4G23_RS00950 0e7d184d9bddd84c9b28589d13804eb7 396 SUPERFAMILY SSF51735 156 354 5.85E-42 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS00950 0e7d184d9bddd84c9b28589d13804eb7 396 SUPERFAMILY SSF50129 1 176 1.22E-58 T 10-11-2016 IPR011032 GroES-like A4G23_RS00950 0e7d184d9bddd84c9b28589d13804eb7 396 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 143 7.8E-27 T 10-11-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A4G23_RS00950 0e7d184d9bddd84c9b28589d13804eb7 396 Gene3D G3DSA:3.90.180.10 1 178 2.8E-48 T 10-11-2016 IPR011032 GroES-like A4G23_RS00950 0e7d184d9bddd84c9b28589d13804eb7 396 Pfam PF13823 Alcohol dehydrogenase GroES-associated 1 23 5.9E-15 T 10-11-2016 IPR027399 Alcohol dehydrogenase GroES-associated A4G23_RS00950 0e7d184d9bddd84c9b28589d13804eb7 396 Gene3D G3DSA:3.40.50.720 179 351 4.2E-53 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS00950 0e7d184d9bddd84c9b28589d13804eb7 396 Pfam PF00107 Zinc-binding dehydrogenase 189 262 2.8E-11 T 10-11-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A4G23_RS00950 0e7d184d9bddd84c9b28589d13804eb7 396 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 10-11-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 A4G23_RS05430 d724fc869337f57526d614a81f1ef93e 446 SUPERFAMILY SSF53850 26 435 6.85E-79 T 10-11-2016 A4G23_RS05430 d724fc869337f57526d614a81f1ef93e 446 Gene3D G3DSA:3.40.190.10 178 367 8.8E-45 T 10-11-2016 A4G23_RS05430 d724fc869337f57526d614a81f1ef93e 446 Gene3D G3DSA:3.40.190.10 44 177 3.9E-24 T 10-11-2016 A4G23_RS05430 d724fc869337f57526d614a81f1ef93e 446 Pfam PF01547 Bacterial extracellular solute-binding protein 57 347 2.4E-41 T 10-11-2016 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 A4G23_RS08645 85e5f4c5f532a1c44452075f67dec831 240 Pfam PF01863 Protein of unknown function DUF45 27 231 4.4E-61 T 10-11-2016 IPR002725 Protein of unknown function DUF45 A4G23_RS07750 5d7b38f04c4c4a460747c642f1f5fb65 259 Pfam PF01925 Sulfite exporter TauE/SafE 13 252 7.7E-40 T 10-11-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 A4G23_RS12265 fa33f3d45cc5af9a5b2aa64e7e0a25c9 275 Gene3D G3DSA:3.40.50.150 43 177 2.7E-7 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS12265 fa33f3d45cc5af9a5b2aa64e7e0a25c9 275 SUPERFAMILY SSF53335 14 184 6.69E-13 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS06050 7c31a44c102034fb4daad03cb27e3a78 241 SUPERFAMILY SSF51366 4 237 3.92E-63 T 10-11-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 A4G23_RS06050 7c31a44c102034fb4daad03cb27e3a78 241 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 5 238 31.66 T 10-11-2016 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 A4G23_RS06050 7c31a44c102034fb4daad03cb27e3a78 241 TIGRFAM TIGR01919 hisA-trpF: bifunctional HisA/TrpF protein 4 239 1.5E-118 T 10-11-2016 IPR010188 Bifunctional HisA/TrpF GO:0000105|GO:0000162|GO:0003949|GO:0004640|GO:0005737 KEGG: 00340+5.3.1.16 A4G23_RS06050 7c31a44c102034fb4daad03cb27e3a78 241 Pfam PF00977 Histidine biosynthesis protein 6 231 6.3E-62 T 10-11-2016 IPR006062 Histidine biosynthesis GO:0000105 A4G23_RS06050 7c31a44c102034fb4daad03cb27e3a78 241 Gene3D G3DSA:3.20.20.70 5 238 7.1E-71 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS04240 d6471018fb1b20010e3aecf4afa05382 92 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 4 48 8.5E-17 T 10-11-2016 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 A4G23_RS04240 d6471018fb1b20010e3aecf4afa05382 92 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 89 20.482 T 10-11-2016 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 A4G23_RS04240 d6471018fb1b20010e3aecf4afa05382 92 Pfam PF02416 mttA/Hcf106 family 4 49 5.6E-16 T 10-11-2016 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 A4G23_RS13955 6a12654d2b418da857b1c277777b223d 97 SMART SM00886 2 97 1.4E-24 T 10-11-2016 IPR013097 Stress responsive alpha-beta barrel A4G23_RS13955 6a12654d2b418da857b1c277777b223d 97 Pfam PF07876 Stress responsive A/B Barrel Domain 2 96 6.2E-21 T 10-11-2016 IPR013097 Stress responsive alpha-beta barrel A4G23_RS13955 6a12654d2b418da857b1c277777b223d 97 SUPERFAMILY SSF54909 2 96 8.72E-17 T 10-11-2016 IPR011008 Dimeric alpha-beta barrel A4G23_RS13955 6a12654d2b418da857b1c277777b223d 97 Gene3D G3DSA:3.30.70.900 1 96 1.6E-23 T 10-11-2016 A4G23_RS17890 242611c4a4d9c30311eb6ffeae21f76b 423 SUPERFAMILY SSF141523 261 393 2.22E-21 T 10-11-2016 A4G23_RS17890 242611c4a4d9c30311eb6ffeae21f76b 423 Gene3D G3DSA:2.40.440.10 261 394 7.1E-19 T 10-11-2016 A4G23_RS17890 242611c4a4d9c30311eb6ffeae21f76b 423 Pfam PF13205 Bacterial Ig-like domain 160 243 9.9E-7 T 10-11-2016 IPR032812 SbsA, Ig-like domain A4G23_RS17890 242611c4a4d9c30311eb6ffeae21f76b 423 Pfam PF03734 L,D-transpeptidase catalytic domain 259 393 3.8E-13 T 10-11-2016 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 A4G23_RS01215 805fa9b8c23c670e598e4da07ffa53d4 124 Pfam PF11239 Protein of unknown function (DUF3040) 5 97 7.1E-6 T 10-11-2016 IPR021401 Protein of unknown function DUF3040 A4G23_RS23805 d8dc32685a091114c3e2dd448bfb4804 149 SUPERFAMILY SSF52833 42 149 1.04E-27 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS23805 d8dc32685a091114c3e2dd448bfb4804 149 Pfam PF00085 Thioredoxin 45 146 5.3E-18 T 10-11-2016 IPR013766 Thioredoxin domain GO:0045454 A4G23_RS23805 d8dc32685a091114c3e2dd448bfb4804 149 Gene3D G3DSA:3.40.30.10 76 149 1.2E-22 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS23805 d8dc32685a091114c3e2dd448bfb4804 149 Gene3D G3DSA:3.40.30.10 2 75 1.3E-9 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS13855 ae62a71db132d1da8b979681d3787de0 271 SUPERFAMILY SSF51695 9 264 2.88E-65 T 10-11-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 A4G23_RS13855 ae62a71db132d1da8b979681d3787de0 271 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 14 260 4.4E-44 T 10-11-2016 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 A4G23_RS13855 ae62a71db132d1da8b979681d3787de0 271 Gene3D G3DSA:3.20.20.190 4 266 3.7E-75 T 10-11-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 A4G23_RS22190 1b6f347696d6441db56439067ebe746e 345 Pfam PF13560 Helix-turn-helix domain 6 85 3.6E-19 T 10-11-2016 A4G23_RS22190 1b6f347696d6441db56439067ebe746e 345 SMART SM00530 10 82 1.3E-8 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS22190 1b6f347696d6441db56439067ebe746e 345 SUPERFAMILY SSF47413 24 81 1.91E-9 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS22190 1b6f347696d6441db56439067ebe746e 345 Gene3D G3DSA:1.10.260.40 5 81 1.3E-19 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS17495 9db6f6111c730c8f8dcb9f434372bd09 705 SUPERFAMILY SSF53822 8 262 4.37E-23 T 10-11-2016 IPR028082 Periplasmic binding protein-like I A4G23_RS17495 9db6f6111c730c8f8dcb9f434372bd09 705 Gene3D G3DSA:3.50.50.60 485 560 1.5E-30 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS17495 9db6f6111c730c8f8dcb9f434372bd09 705 Gene3D G3DSA:3.50.50.60 660 699 1.5E-30 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS17495 9db6f6111c730c8f8dcb9f434372bd09 705 Gene3D G3DSA:3.50.50.60 340 423 1.5E-30 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS17495 9db6f6111c730c8f8dcb9f434372bd09 705 Pfam PF01266 FAD dependent oxidoreductase 348 698 4.1E-35 T 10-11-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A4G23_RS17495 9db6f6111c730c8f8dcb9f434372bd09 705 Pfam PF13458 Periplasmic binding protein 8 162 9.7E-14 T 10-11-2016 IPR028081 Leucine-binding protein domain A4G23_RS17495 9db6f6111c730c8f8dcb9f434372bd09 705 SUPERFAMILY SSF51905 347 561 6.47E-31 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS17495 9db6f6111c730c8f8dcb9f434372bd09 705 SUPERFAMILY SSF51905 659 700 6.47E-31 T 10-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4G23_RS17495 9db6f6111c730c8f8dcb9f434372bd09 705 Gene3D G3DSA:3.30.9.10 424 484 4.1E-9 T 10-11-2016 A4G23_RS17495 9db6f6111c730c8f8dcb9f434372bd09 705 Gene3D G3DSA:3.40.50.2300 8 159 6.2E-19 T 10-11-2016 A4G23_RS16835 6e559b2833a932f1b5855ffa5fa91ede 402 Gene3D G3DSA:1.10.260.40 22 79 8.2E-7 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS16835 6e559b2833a932f1b5855ffa5fa91ede 402 SUPERFAMILY SSF47413 20 79 2.94E-7 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS20160 5a9d7a22cdb3e4269349b02d6f17a104 182 Gene3D G3DSA:3.40.630.30 5 181 2.6E-48 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS20160 5a9d7a22cdb3e4269349b02d6f17a104 182 SUPERFAMILY SSF55729 14 160 8.83E-27 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS20160 5a9d7a22cdb3e4269349b02d6f17a104 182 Pfam PF13527 Acetyltransferase (GNAT) domain 19 130 1.2E-9 T 10-11-2016 A4G23_RS14295 ae54781d87216f82bc746361d4792a3d 151 SUPERFAMILY SSF158682 15 150 5.75E-24 T 10-11-2016 IPR029024 TerB-like A4G23_RS14295 ae54781d87216f82bc746361d4792a3d 151 Pfam PF05099 Tellurite resistance protein TerB 11 150 3.4E-31 T 10-11-2016 IPR007791 Co-chaperone DjlA, N-terminal A4G23_RS14295 ae54781d87216f82bc746361d4792a3d 151 Gene3D G3DSA:1.10.3680.10 21 150 1.4E-22 T 10-11-2016 IPR029024 TerB-like A4G23_RS13200 b988c216391f836d3b88f415c2b5e935 957 Pfam PF02687 FtsX-like permease family 323 426 2.2E-9 T 10-11-2016 IPR003838 ABC transporter permease protein domain GO:0016020 A4G23_RS05525 54d9c005a38bb4d1b3c000458c5d506a 132 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 11 126 3.3E-29 T 10-11-2016 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III A4G23_RS11115 2da15c5f69b0673cc63e60d556d65edc 67 Pfam PF04149 Domain of unknown function (DUF397) 10 61 8.5E-21 T 10-11-2016 IPR007278 Domain of unknown function DUF397 A4G23_RS17920 5bf6a3ab21eb9c97be45bc8a00805fda 529 Pfam PF01435 Peptidase family M48 82 347 2.7E-13 T 10-11-2016 IPR001915 Peptidase M48 GO:0004222|GO:0006508 A4G23_RS17920 5bf6a3ab21eb9c97be45bc8a00805fda 529 Gene3D G3DSA:3.30.2010.10 76 167 6.0E-13 T 10-11-2016 A4G23_RS07735 a5487de79f82189414a8454183074a71 189 Pfam PF03358 NADPH-dependent FMN reductase 2 146 1.8E-38 T 10-11-2016 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 A4G23_RS07735 a5487de79f82189414a8454183074a71 189 Gene3D G3DSA:3.40.50.360 2 180 6.0E-47 T 10-11-2016 IPR029039 Flavoprotein-like domain A4G23_RS07735 a5487de79f82189414a8454183074a71 189 SUPERFAMILY SSF52218 2 161 3.67E-37 T 10-11-2016 IPR029039 Flavoprotein-like domain A4G23_RS05550 8261df39826bcbced800f1559624e539 112 Pfam PF01883 Domain of unknown function DUF59 14 74 3.7E-19 T 10-11-2016 IPR002744 Domain of unknown function DUF59 A4G23_RS05550 8261df39826bcbced800f1559624e539 112 SUPERFAMILY SSF117916 12 106 1.41E-27 T 10-11-2016 A4G23_RS24830 4023efb23b28f3e64ddb9fdc188783e8 225 Pfam PF03729 Short repeat of unknown function (DUF308) 25 93 3.5E-9 T 10-11-2016 IPR005325 Protein of unknown function DUF308, membrane A4G23_RS24830 4023efb23b28f3e64ddb9fdc188783e8 225 Pfam PF03729 Short repeat of unknown function (DUF308) 80 149 2.8E-7 T 10-11-2016 IPR005325 Protein of unknown function DUF308, membrane A4G23_RS08940 3dd9443ff03b2253c2ee2fe0946a855a 259 Pfam PF15698 Phosphatase 9 258 1.9E-110 T 10-11-2016 IPR031423 Uncharacterised phosphatase SCO2771 A4G23_RS20945 f2fc4fc5bf5cd438afb28e728030e628 510 Pfam PF05108 Type VII secretion system ESX-1, transport TM domain B 3 506 9.5E-76 T 10-11-2016 IPR007795 Type VII secretion system EccB A4G23_RS20945 f2fc4fc5bf5cd438afb28e728030e628 510 TIGRFAM TIGR03919 T7SS_EccB: type VII secretion protein EccB 4 452 1.3E-46 T 10-11-2016 IPR007795 Type VII secretion system EccB A4G23_RS10790 3f8bc00728db0a87a5d01fac1b1016e4 161 Gene3D G3DSA:3.40.630.30 7 155 3.2E-24 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS10790 3f8bc00728db0a87a5d01fac1b1016e4 161 Pfam PF00583 Acetyltransferase (GNAT) family 55 137 3.7E-9 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS10790 3f8bc00728db0a87a5d01fac1b1016e4 161 SUPERFAMILY SSF55729 2 149 1.36E-23 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS08760 69ac750f2f878c99abe4bf6492d1b27c 272 SUPERFAMILY SSF51658 9 268 3.54E-56 T 10-11-2016 IPR013022 Xylose isomerase-like, TIM barrel domain A4G23_RS08760 69ac750f2f878c99abe4bf6492d1b27c 272 Pfam PF01261 Xylose isomerase-like TIM barrel 27 224 3.4E-31 T 10-11-2016 IPR013022 Xylose isomerase-like, TIM barrel domain A4G23_RS08760 69ac750f2f878c99abe4bf6492d1b27c 272 Gene3D G3DSA:3.20.20.150 12 271 1.2E-67 T 10-11-2016 IPR013022 Xylose isomerase-like, TIM barrel domain A4G23_RS07010 5fd0bf2da47e8b766cb8b0db4484962d 249 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 39 214 1.4E-27 T 10-11-2016 IPR015330 DNA primase/polymerase, bifunctional, N-terminal A4G23_RS07010 5fd0bf2da47e8b766cb8b0db4484962d 249 SMART SM00943 37 219 2.7E-36 T 10-11-2016 IPR015330 DNA primase/polymerase, bifunctional, N-terminal A4G23_RS25005 4c69ce3516f4ebf33229357515fe3d85 72 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 15 67 4.1E-12 T 10-11-2016 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 A4G23_RS07265 de5aec83547b7c3297bdcf92f1eec55a 68 Pfam PF04149 Domain of unknown function (DUF397) 9 64 2.5E-21 T 10-11-2016 IPR007278 Domain of unknown function DUF397 A4G23_RS03060 95bb91d90883eebed600230f0201992d 157 Pfam PF02577 Bifunctional nuclease 6 128 4.7E-45 T 10-11-2016 IPR003729 Bifunctional nuclease domain GO:0004518 A4G23_RS03060 95bb91d90883eebed600230f0201992d 157 SUPERFAMILY SSF103256 3 136 2.09E-46 T 10-11-2016 IPR003729 Bifunctional nuclease domain GO:0004518 A4G23_RS07245 2652dd703bfd0e4feca47c1c80f3bcf9 428 Gene3D G3DSA:2.70.70.10 200 301 3.8E-11 T 10-11-2016 A4G23_RS07245 2652dd703bfd0e4feca47c1c80f3bcf9 428 Pfam PF01551 Peptidase family M23 216 301 8.2E-9 T 10-11-2016 IPR016047 Peptidase M23 A4G23_RS07245 2652dd703bfd0e4feca47c1c80f3bcf9 428 SUPERFAMILY SSF51261 194 298 8.89E-11 T 10-11-2016 IPR011055 Duplicated hybrid motif A4G23_RS00435 eb509e627df7c6360dbba111b514e5bb 364 Hamap MF_01609 Glutamate--cysteine ligase [gshA]. 1 364 72.895 T 10-11-2016 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 A4G23_RS00435 eb509e627df7c6360dbba111b514e5bb 364 SUPERFAMILY SSF55931 4 356 2.84E-87 T 10-11-2016 A4G23_RS00435 eb509e627df7c6360dbba111b514e5bb 364 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 5 282 1.4E-52 T 10-11-2016 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 A4G23_RS00435 eb509e627df7c6360dbba111b514e5bb 364 TIGRFAM TIGR02050 gshA_cyan_rel: carboxylate-amine ligase, YbdK family 5 287 1.9E-81 T 10-11-2016 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 A4G23_RS09560 de040f108b844817cae3a024e412a4ec 123 Pfam PF02661 Fic/DOC family 20 80 7.1E-7 T 10-11-2016 IPR003812 Fido domain A4G23_RS08375 489cc5806e0bbe63df9de92633439f1a 495 Pfam PF00324 Amino acid permease 36 440 2.7E-98 T 10-11-2016 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 A4G23_RS08375 489cc5806e0bbe63df9de92633439f1a 495 ProSitePatterns PS00218 Amino acid permeases signature. 61 91 - T 10-11-2016 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 A4G23_RS08375 489cc5806e0bbe63df9de92633439f1a 495 PIRSF PIRSF006060 14 478 1.3E-64 T 10-11-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A4G23_RS21525 2cbee393df59e0ad993193ec195d04f7 191 Gene3D G3DSA:3.10.129.10 18 164 1.7E-43 T 10-11-2016 IPR029069 HotDog domain A4G23_RS21525 2cbee393df59e0ad993193ec195d04f7 191 SUPERFAMILY SSF54637 18 156 7.31E-32 T 10-11-2016 IPR029069 HotDog domain A4G23_RS21525 2cbee393df59e0ad993193ec195d04f7 191 Pfam PF03061 Thioesterase superfamily 72 138 3.8E-7 T 10-11-2016 IPR006683 Thioesterase domain Reactome: R-HSA-75105 A4G23_RS14375 1f4331daf82fb3180b22b87785b24447 195 Pfam PF06197 Protein of unknown function (DUF998) 10 186 6.9E-34 T 10-11-2016 IPR009339 Protein of unknown function DUF998 A4G23_RS21485 5d3b8baeb3cb093b1d82b7ae81c20984 375 Hamap MF_00323 Ferrochelatase [hemH]. 9 330 30.195 T 10-11-2016 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 A4G23_RS21485 5d3b8baeb3cb093b1d82b7ae81c20984 375 Gene3D G3DSA:3.40.50.1400 165 310 2.5E-45 T 10-11-2016 A4G23_RS21485 5d3b8baeb3cb093b1d82b7ae81c20984 375 SUPERFAMILY SSF53800 9 343 3.43E-80 T 10-11-2016 A4G23_RS21485 5d3b8baeb3cb093b1d82b7ae81c20984 375 Pfam PF00762 Ferrochelatase 11 329 2.7E-90 T 10-11-2016 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 A4G23_RS21485 5d3b8baeb3cb093b1d82b7ae81c20984 375 Gene3D G3DSA:3.40.50.1400 9 164 1.1E-38 T 10-11-2016 A4G23_RS21955 cb594c5be49031d9175566488d3da884 401 Gene3D G3DSA:3.40.50.1820 71 251 1.8E-9 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS21955 cb594c5be49031d9175566488d3da884 401 SUPERFAMILY SSF53474 72 251 8.34E-11 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS04710 bed95f8ce1db5bd39534ffefe03ce3b6 269 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 40 257 2.1E-23 T 10-11-2016 IPR013830 SGNH hydrolase-type esterase domain A4G23_RS04710 bed95f8ce1db5bd39534ffefe03ce3b6 269 SUPERFAMILY SSF52266 36 257 1.13E-60 T 10-11-2016 IPR013830 SGNH hydrolase-type esterase domain A4G23_RS04710 bed95f8ce1db5bd39534ffefe03ce3b6 269 Gene3D G3DSA:3.40.50.1110 33 258 5.7E-68 T 10-11-2016 IPR013830 SGNH hydrolase-type esterase domain A4G23_RS15650 0d4e886c33678e3d7c7d39b328769b65 86 Pfam PF04149 Domain of unknown function (DUF397) 32 81 5.0E-20 T 10-11-2016 IPR007278 Domain of unknown function DUF397 A4G23_RS15650 0d4e886c33678e3d7c7d39b328769b65 86 Pfam PF04149 Domain of unknown function (DUF397) 14 31 1.4E-5 T 10-11-2016 IPR007278 Domain of unknown function DUF397 A4G23_RS16140 bd94c01c6480a88ec1a88369de1fb311 449 Gene3D G3DSA:2.50.20.10 108 289 1.4E-15 T 10-11-2016 A4G23_RS16140 bd94c01c6480a88ec1a88369de1fb311 449 SUPERFAMILY SSF89392 114 289 1.92E-13 T 10-11-2016 IPR029046 Lipoprotein localisation LolA/LolB/LppX A4G23_RS14750 ef0fa8070a251c203b8ca4b9ba072eea 249 Pfam PF02104 SURF1 family 19 222 4.4E-19 T 10-11-2016 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS20490 39b4ba6a2ab6ccc0874103ad92adac9b 257 Pfam PF08241 Methyltransferase domain 22 59 2.0E-4 T 10-11-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 A4G23_RS20490 39b4ba6a2ab6ccc0874103ad92adac9b 257 SUPERFAMILY SSF53335 7 199 6.49E-16 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS20490 39b4ba6a2ab6ccc0874103ad92adac9b 257 Gene3D G3DSA:3.40.50.150 6 255 5.1E-15 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS26615 c06109ad03a62611eb3c41b320aa5a51 197 SUPERFAMILY SSF55729 114 181 1.51E-12 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS26615 c06109ad03a62611eb3c41b320aa5a51 197 SUPERFAMILY SSF55729 38 81 1.51E-12 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS26615 c06109ad03a62611eb3c41b320aa5a51 197 Gene3D G3DSA:3.40.630.30 15 184 8.0E-19 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS26615 c06109ad03a62611eb3c41b320aa5a51 197 Pfam PF13508 Acetyltransferase (GNAT) domain 118 177 3.8E-6 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS09130 71ffa20c2e68bc76ad8c04cdb7e47a13 274 Gene3D G3DSA:3.10.180.10 3 127 1.1E-28 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS09130 71ffa20c2e68bc76ad8c04cdb7e47a13 274 SUPERFAMILY SSF54593 5 125 7.43E-20 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS27225 301ba3d8f8396c88c3358e5c0bf011fe 425 SUPERFAMILY SSF103473 13 399 1.44E-29 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS27225 301ba3d8f8396c88c3358e5c0bf011fe 425 Pfam PF07690 Major Facilitator Superfamily 25 352 2.1E-22 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS27225 301ba3d8f8396c88c3358e5c0bf011fe 425 Gene3D G3DSA:1.20.1250.20 13 197 7.0E-17 T 10-11-2016 A4G23_RS27225 301ba3d8f8396c88c3358e5c0bf011fe 425 Gene3D G3DSA:1.20.1250.20 223 399 2.5E-6 T 10-11-2016 A4G23_RS00730 63a39ba0b4b7641cf3da0f9aaf307500 463 Gene3D G3DSA:3.40.605.10 3 247 1.5E-71 T 10-11-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A4G23_RS00730 63a39ba0b4b7641cf3da0f9aaf307500 463 Pfam PF00171 Aldehyde dehydrogenase family 3 459 4.4E-141 T 10-11-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A4G23_RS00730 63a39ba0b4b7641cf3da0f9aaf307500 463 Gene3D G3DSA:3.40.309.10 248 434 5.1E-62 T 10-11-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 A4G23_RS00730 63a39ba0b4b7641cf3da0f9aaf307500 463 SUPERFAMILY SSF53720 3 461 3.53E-142 T 10-11-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A4G23_RS19815 b131cc21db76b1cba3d3c73234b774f9 458 Gene3D G3DSA:1.10.3860.10 7 407 1.3E-103 T 10-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4G23_RS19815 b131cc21db76b1cba3d3c73234b774f9 458 PRINTS PR00173 Glutamate-aspartate symporter signature 5 25 1.4E-29 T 10-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4G23_RS19815 b131cc21db76b1cba3d3c73234b774f9 458 PRINTS PR00173 Glutamate-aspartate symporter signature 76 101 1.4E-29 T 10-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4G23_RS19815 b131cc21db76b1cba3d3c73234b774f9 458 PRINTS PR00173 Glutamate-aspartate symporter signature 292 318 1.4E-29 T 10-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4G23_RS19815 b131cc21db76b1cba3d3c73234b774f9 458 PRINTS PR00173 Glutamate-aspartate symporter signature 191 210 1.4E-29 T 10-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4G23_RS19815 b131cc21db76b1cba3d3c73234b774f9 458 PRINTS PR00173 Glutamate-aspartate symporter signature 327 346 1.4E-29 T 10-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4G23_RS19815 b131cc21db76b1cba3d3c73234b774f9 458 PRINTS PR00173 Glutamate-aspartate symporter signature 46 66 1.4E-29 T 10-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4G23_RS19815 b131cc21db76b1cba3d3c73234b774f9 458 Pfam PF00375 Sodium:dicarboxylate symporter family 11 400 1.6E-99 T 10-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4G23_RS19815 b131cc21db76b1cba3d3c73234b774f9 458 SUPERFAMILY SSF118215 11 401 3.92E-101 T 10-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4G23_RS10530 b297f1fb1a992a996ef0933d346a7d9f 167 Pfam PF14433 SUKH-3 immunity protein 9 153 3.9E-44 T 10-11-2016 IPR025850 SUKH-3 immunity protein A4G23_RS04135 264ec4ac17b4ac8acde688f86fb227dd 248 Pfam PF07179 SseB protein N-terminal domain 22 142 8.0E-30 T 10-11-2016 IPR009839 SseB protein N-terminal domain A4G23_RS07200 97cd4beec1dfd3069891fe0fba707afa 172 Pfam PF12822 Protein of unknown function (DUF3816) 88 171 3.4E-14 T 10-11-2016 IPR024529 ECF transporter, substrate-specific component GO:0005215 A4G23_RS07200 97cd4beec1dfd3069891fe0fba707afa 172 PIRSF PIRSF037395 16 172 4.9E-66 T 10-11-2016 IPR017196 ECF transporter, predicted substrate-specific component UCP037395 A4G23_RS26370 0b4f0556eeb3fa0fb64de0092352d3b3 134 Pfam PF03965 Penicillinase repressor 19 125 1.3E-20 T 10-11-2016 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 A4G23_RS26370 0b4f0556eeb3fa0fb64de0092352d3b3 134 Gene3D G3DSA:1.10.10.10 19 86 2.6E-15 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS26370 0b4f0556eeb3fa0fb64de0092352d3b3 134 SUPERFAMILY SSF46785 19 127 4.54E-17 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS05480 1d9e89a597f9cc1987bbe07e98640caf 272 SUPERFAMILY SSF51735 4 243 5.68E-41 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS05480 1d9e89a597f9cc1987bbe07e98640caf 272 Gene3D G3DSA:3.40.50.720 5 215 1.5E-30 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS05480 1d9e89a597f9cc1987bbe07e98640caf 272 Pfam PF01370 NAD dependent epimerase/dehydratase family 7 170 4.5E-15 T 10-11-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 A4G23_RS07140 ef36f95832e83c026d476b9e77104c61 230 SUPERFAMILY SSF53335 47 200 8.66E-15 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS07140 ef36f95832e83c026d476b9e77104c61 230 Pfam PF13578 Methyltransferase domain 51 179 7.2E-22 T 10-11-2016 A4G23_RS07140 ef36f95832e83c026d476b9e77104c61 230 Gene3D G3DSA:3.40.50.150 50 182 1.4E-11 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS15200 2f1a3dcb3c7e57d1c3f4a9529c2beb50 82 Pfam PF04149 Domain of unknown function (DUF397) 19 72 8.5E-18 T 10-11-2016 IPR007278 Domain of unknown function DUF397 A4G23_RS18450 04d4cd594fe71998899a1dd87360d6ff 331 Pfam PF00005 ABC transporter 23 181 1.4E-26 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS18450 04d4cd594fe71998899a1dd87360d6ff 331 SMART SM00382 31 231 1.3E-14 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS18450 04d4cd594fe71998899a1dd87360d6ff 331 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 233 297 1.3E-21 T 10-11-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A4G23_RS18450 04d4cd594fe71998899a1dd87360d6ff 331 Gene3D G3DSA:3.40.50.300 2 255 7.0E-76 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS18450 04d4cd594fe71998899a1dd87360d6ff 331 SUPERFAMILY SSF52540 2 252 1.81E-68 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS18450 04d4cd594fe71998899a1dd87360d6ff 331 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS18450 04d4cd594fe71998899a1dd87360d6ff 331 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 231 317 6.7E-28 T 10-11-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A4G23_RS26610 f6c0d547539cef5c10d2dada1396ba3c 88 Pfam PF02583 Metal-sensitive transcriptional repressor 12 78 1.4E-23 T 10-11-2016 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 A4G23_RS01995 f6ac49559e0aa88064f6fa8926e2eb40 231 Gene3D G3DSA:1.20.144.10 35 221 7.3E-33 T 10-11-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A4G23_RS01995 f6ac49559e0aa88064f6fa8926e2eb40 231 SUPERFAMILY SSF48317 23 216 1.19E-33 T 10-11-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A4G23_RS01995 f6ac49559e0aa88064f6fa8926e2eb40 231 SMART SM00014 93 208 1.3E-17 T 10-11-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A4G23_RS01995 f6ac49559e0aa88064f6fa8926e2eb40 231 Pfam PF01569 PAP2 superfamily 99 213 2.9E-24 T 10-11-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A4G23_RS20655 edb37abd62121f5d7c926634c534543a 478 SUPERFAMILY SSF53720 5 476 8.12E-162 T 10-11-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A4G23_RS20655 edb37abd62121f5d7c926634c534543a 478 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 278 289 - T 10-11-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 A4G23_RS20655 edb37abd62121f5d7c926634c534543a 478 Gene3D G3DSA:3.40.309.10 265 453 1.1E-63 T 10-11-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 A4G23_RS20655 edb37abd62121f5d7c926634c534543a 478 Pfam PF00171 Aldehyde dehydrogenase family 19 473 5.7E-163 T 10-11-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A4G23_RS20655 edb37abd62121f5d7c926634c534543a 478 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 250 257 - T 10-11-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 A4G23_RS20655 edb37abd62121f5d7c926634c534543a 478 Gene3D G3DSA:3.40.605.10 7 264 2.9E-94 T 10-11-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A4G23_RS17930 f07e98a26d42e9d25b750e47cd9ffd40 384 PIRSF PIRSF001434 1 384 3.7E-144 T 10-11-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A4G23_RS17930 f07e98a26d42e9d25b750e47cd9ffd40 384 SUPERFAMILY SSF53383 11 383 1.71E-124 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS17930 f07e98a26d42e9d25b750e47cd9ffd40 384 Gene3D G3DSA:3.40.640.10 9 252 9.2E-101 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS17930 f07e98a26d42e9d25b750e47cd9ffd40 384 Gene3D G3DSA:3.90.1150.10 253 383 1.5E-50 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS17930 f07e98a26d42e9d25b750e47cd9ffd40 384 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 11 383 2.1E-147 T 10-11-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A4G23_RS17930 f07e98a26d42e9d25b750e47cd9ffd40 384 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 196 210 - T 10-11-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A4G23_RS00510 e4a5d57cdb5c04c6a0bbb59eb04faba7 259 Pfam PF06386 Gas vesicle synthesis protein GvpL/GvpF 10 256 8.8E-59 T 10-11-2016 IPR009430 Gas vesicle protein GvpL/GvpF GO:0031411|GO:0031412 A4G23_RS06030 537b5a0d03a87ec6754eedd670383d28 210 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 5 185 4.1E-39 T 10-11-2016 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type A4G23_RS06030 537b5a0d03a87ec6754eedd670383d28 210 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 12 85 1.2E-7 T 10-11-2016 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 A4G23_RS06030 537b5a0d03a87ec6754eedd670383d28 210 TIGRFAM TIGR03085 TIGR03085: TIGR03085 family protein 5 203 4.5E-78 T 10-11-2016 IPR017519 Conserved hypothetical protein CHP03085 A4G23_RS06030 537b5a0d03a87ec6754eedd670383d28 210 SUPERFAMILY SSF109854 12 114 4.03E-8 T 10-11-2016 A4G23_RS07730 4241ee64e448e3ce5d14ff385de8bf40 227 Gene3D G3DSA:3.40.50.620 50 175 1.4E-13 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS07730 4241ee64e448e3ce5d14ff385de8bf40 227 Pfam PF02698 DUF218 domain 56 178 3.8E-28 T 10-11-2016 IPR003848 Domain of unknown function DUF218 A4G23_RS24385 c554dce8d2e7166b554856ce1f64a9d3 192 SUPERFAMILY SSF55729 9 179 2.71E-33 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS24385 c554dce8d2e7166b554856ce1f64a9d3 192 Pfam PF13302 Acetyltransferase (GNAT) domain 17 155 2.8E-19 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS24385 c554dce8d2e7166b554856ce1f64a9d3 192 Gene3D G3DSA:3.40.630.30 8 180 2.7E-44 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS10905 b0fd603b9ae9b4c997ef26b5ffbf7380 428 SUPERFAMILY SSF103473 20 402 9.81E-29 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS10905 b0fd603b9ae9b4c997ef26b5ffbf7380 428 Pfam PF07690 Major Facilitator Superfamily 245 416 6.5E-11 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS10905 b0fd603b9ae9b4c997ef26b5ffbf7380 428 Gene3D G3DSA:1.20.1250.20 25 202 5.4E-8 T 10-11-2016 A4G23_RS10905 b0fd603b9ae9b4c997ef26b5ffbf7380 428 Gene3D G3DSA:1.20.1250.20 228 399 2.5E-14 T 10-11-2016 A4G23_RS08595 8f8befa274aa83d00758c074d35c517a 63 Pfam PF05122 Mobile element transfer protein 12 61 3.6E-29 T 10-11-2016 IPR007806 Mobile element transfer A4G23_RS06680 5ebfc77038d7e0f8763856a95230bb0a 267 Pfam PF02654 Cobalamin-5-phosphate synthase 16 262 8.2E-46 T 10-11-2016 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 A4G23_RS06680 5ebfc77038d7e0f8763856a95230bb0a 267 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 267 41.274 T 10-11-2016 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 A4G23_RS16520 f540f887bc61efba1ed7a2453746718f 154 SUPERFAMILY SSF46785 9 147 1.91E-11 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS16520 f540f887bc61efba1ed7a2453746718f 154 Gene3D G3DSA:1.10.10.10 15 143 7.2E-16 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS15305 8a8715d1aecead279c35672e3aae7e8a 624 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 250 558 2.0E-105 T 10-11-2016 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal A4G23_RS15305 8a8715d1aecead279c35672e3aae7e8a 624 Pfam PF16995 Transmembrane region of lysyl-tRNA synthetase 26 227 1.2E-12 T 10-11-2016 IPR031553 Lysyl-tRNA synthetase, N-terminal transmembrane region KEGG: 00970+6.1.1.6 A4G23_RS27275 69bbfefe64cff7965f165bbef0bac000 232 Pfam PF00561 alpha/beta hydrolase fold 25 122 2.5E-20 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS27275 69bbfefe64cff7965f165bbef0bac000 232 SUPERFAMILY SSF53474 3 225 3.41E-57 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS27275 69bbfefe64cff7965f165bbef0bac000 232 PRINTS PR00111 Alpha/beta hydrolase fold signature 50 65 1.6E-8 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS27275 69bbfefe64cff7965f165bbef0bac000 232 PRINTS PR00111 Alpha/beta hydrolase fold signature 107 120 1.6E-8 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS27275 69bbfefe64cff7965f165bbef0bac000 232 PRINTS PR00111 Alpha/beta hydrolase fold signature 93 106 1.6E-8 T 10-11-2016 IPR000073 Alpha/beta hydrolase fold-1 A4G23_RS27275 69bbfefe64cff7965f165bbef0bac000 232 Gene3D G3DSA:3.40.50.1820 141 226 3.5E-13 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS27275 69bbfefe64cff7965f165bbef0bac000 232 Gene3D G3DSA:3.40.50.1820 2 140 4.0E-44 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS05215 3dc18a7734eed0486d0df732c9a65a08 240 Pfam PF01988 VIT family 25 232 5.5E-58 T 10-11-2016 IPR008217 Ccc1 family A4G23_RS13885 2686831581ba2d71bcc4ac5d5e8a8446 152 Pfam PF00720 Subtilisin inhibitor-like 44 126 2.3E-10 T 10-11-2016 IPR023549 Subtilisin inhibitor GO:0004867 A4G23_RS13885 2686831581ba2d71bcc4ac5d5e8a8446 152 Gene3D G3DSA:3.30.350.10 43 146 1.6E-30 T 10-11-2016 IPR023549 Subtilisin inhibitor GO:0004867 A4G23_RS13885 2686831581ba2d71bcc4ac5d5e8a8446 152 SUPERFAMILY SSF55399 43 146 1.05E-22 T 10-11-2016 IPR023549 Subtilisin inhibitor GO:0004867 A4G23_RS13885 2686831581ba2d71bcc4ac5d5e8a8446 152 ProDom PD004028 INHIBITOR PROTEASE SERINE DIRECT SEQUENCING SUBTILISIN PRECURSOR SIGNAL INHIBITOR-LIKE INHIBITOR 72 138 9.0E-8 T 10-11-2016 IPR023549 Subtilisin inhibitor GO:0004867 A4G23_RS06840 1ec571708d16d9abc55baa1dcb625cc3 170 Pfam PF14062 Domain of unknown function (DUF4253) 65 170 2.8E-22 T 10-11-2016 IPR025349 Domain of unknown function DUF4253 A4G23_RS02355 e95874fba6547124592fdca248bbf3a4 711 Pfam PF02446 4-alpha-glucanotransferase 154 681 5.5E-95 T 10-11-2016 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 A4G23_RS02355 e95874fba6547124592fdca248bbf3a4 711 Gene3D G3DSA:3.20.20.80 630 684 3.1E-135 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS02355 e95874fba6547124592fdca248bbf3a4 711 Gene3D G3DSA:3.20.20.80 145 578 3.1E-135 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS02355 e95874fba6547124592fdca248bbf3a4 711 SUPERFAMILY SSF51445 146 575 1.66E-118 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS02355 e95874fba6547124592fdca248bbf3a4 711 SUPERFAMILY SSF51445 626 685 1.66E-118 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS02355 e95874fba6547124592fdca248bbf3a4 711 TIGRFAM TIGR00217 malQ: 4-alpha-glucanotransferase 111 606 6.2E-76 T 10-11-2016 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 A4G23_RS05595 d5b302f1372678ece69acc68a4825c12 255 PIRSF PIRSF006648 3 255 1.0E-31 T 10-11-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 A4G23_RS05595 d5b302f1372678ece69acc68a4825c12 255 Pfam PF01061 ABC-2 type transporter 30 222 3.4E-22 T 10-11-2016 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A4G23_RS26585 e0e8e81464d314e4e84bb70217cd6711 116 SMART SM00450 4 98 4.7E-20 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS26585 e0e8e81464d314e4e84bb70217cd6711 116 Pfam PF00581 Rhodanese-like domain 16 94 8.4E-15 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS26585 e0e8e81464d314e4e84bb70217cd6711 116 Gene3D G3DSA:3.40.250.10 2 100 2.7E-28 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS26585 e0e8e81464d314e4e84bb70217cd6711 116 SUPERFAMILY SSF52821 2 102 7.6E-32 T 10-11-2016 IPR001763 Rhodanese-like domain A4G23_RS11670 752d9e751ed5290d3459d623c38b062b 193 Pfam PF13302 Acetyltransferase (GNAT) domain 13 154 6.3E-27 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS11670 752d9e751ed5290d3459d623c38b062b 193 SUPERFAMILY SSF55729 7 181 7.16E-33 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS11670 752d9e751ed5290d3459d623c38b062b 193 Gene3D G3DSA:3.40.630.30 4 186 4.0E-42 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS02325 873a28d2b80249c892d712f208e52989 234 Gene3D G3DSA:3.90.470.20 117 170 3.3E-14 T 10-11-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 A4G23_RS02325 873a28d2b80249c892d712f208e52989 234 Gene3D G3DSA:3.90.470.20 21 116 8.0E-19 T 10-11-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 A4G23_RS02325 873a28d2b80249c892d712f208e52989 234 SUPERFAMILY SSF56214 105 209 3.66E-15 T 10-11-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 A4G23_RS02325 873a28d2b80249c892d712f208e52989 234 SUPERFAMILY SSF56214 8 97 5.58E-15 T 10-11-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 A4G23_RS02325 873a28d2b80249c892d712f208e52989 234 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 106 167 2.5E-10 T 10-11-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 A4G23_RS08265 ff05d6649d8ab7510e4b6e80d5bda4d8 341 Pfam PF04085 rod shape-determining protein MreC 131 270 3.9E-34 T 10-11-2016 IPR007221 Rod shape-determining protein MreC GO:0008360 A4G23_RS20970 0c04d238aa203da8f496f48bb1bbb266 119 Gene3D G3DSA:1.10.287.1060 1 95 4.5E-10 T 10-11-2016 A4G23_RS20970 0c04d238aa203da8f496f48bb1bbb266 119 Pfam PF06013 Proteins of 100 residues with WXG 6 82 5.6E-7 T 10-11-2016 IPR010310 Type VII secretion system ESAT-6-like A4G23_RS20970 0c04d238aa203da8f496f48bb1bbb266 119 SUPERFAMILY SSF140453 8 96 2.09E-11 T 10-11-2016 IPR010310 Type VII secretion system ESAT-6-like A4G23_RS26680 0395a0b80e09e142d3a68ea33019895c 272 SUPERFAMILY SSF51735 2 208 3.65E-31 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS26680 0395a0b80e09e142d3a68ea33019895c 272 Gene3D G3DSA:3.40.50.720 2 195 1.4E-21 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS26680 0395a0b80e09e142d3a68ea33019895c 272 Pfam PF05368 NmrA-like family 54 138 8.8E-5 T 10-11-2016 IPR008030 NmrA-like domain Reactome: R-HSA-70635 A4G23_RS23560 d981282eace8de95364d8660cae560e5 536 SUPERFAMILY SSF53383 37 219 1.12E-84 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS23560 d981282eace8de95364d8660cae560e5 536 SUPERFAMILY SSF53383 259 516 1.12E-84 T 10-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase A4G23_RS23560 d981282eace8de95364d8660cae560e5 536 Gene3D G3DSA:3.90.1150.10 397 517 6.4E-26 T 10-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 A4G23_RS23560 d981282eace8de95364d8660cae560e5 536 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 267 443 4.9E-27 T 10-11-2016 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 A4G23_RS23560 d981282eace8de95364d8660cae560e5 536 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 66 197 2.6E-6 T 10-11-2016 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 A4G23_RS23560 d981282eace8de95364d8660cae560e5 536 Gene3D G3DSA:3.40.640.10 94 220 4.2E-72 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS23560 d981282eace8de95364d8660cae560e5 536 Gene3D G3DSA:3.40.640.10 260 396 4.2E-72 T 10-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A4G23_RS00050 3ef649df90921651ff31584fb154eeb1 246 Pfam PF03457 Helicase associated domain 88 148 4.6E-7 T 10-11-2016 IPR005114 Helicase-associated A4G23_RS00050 3ef649df90921651ff31584fb154eeb1 246 Pfam PF03457 Helicase associated domain 172 243 5.5E-7 T 10-11-2016 IPR005114 Helicase-associated A4G23_RS00050 3ef649df90921651ff31584fb154eeb1 246 Pfam PF03457 Helicase associated domain 7 78 9.2E-7 T 10-11-2016 IPR005114 Helicase-associated A4G23_RS24650 7587c57fba11078d99200f5b626d2ed6 288 Pfam PF13560 Helix-turn-helix domain 15 74 1.5E-13 T 10-11-2016 A4G23_RS24650 7587c57fba11078d99200f5b626d2ed6 288 SUPERFAMILY SSF47413 14 72 5.63E-9 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS24650 7587c57fba11078d99200f5b626d2ed6 288 Gene3D G3DSA:1.10.260.40 12 71 7.2E-10 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS24650 7587c57fba11078d99200f5b626d2ed6 288 SMART SM00530 18 73 2.5E-9 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS19835 db0d5f44913864c945e230d256c0a182 482 SUPERFAMILY SSF56112 153 438 1.16E-21 T 10-11-2016 IPR011009 Protein kinase-like domain A4G23_RS19835 db0d5f44913864c945e230d256c0a182 482 Gene3D G3DSA:3.90.1200.10 250 420 1.2E-7 T 10-11-2016 A4G23_RS16295 f6443ea89d7cf14ef787277a653f39b1 151 Pfam PF13452 N-terminal half of MaoC dehydratase 7 138 9.1E-37 T 10-11-2016 A4G23_RS16295 f6443ea89d7cf14ef787277a653f39b1 151 Hamap MF_00799 UPF0336 protein . 1 149 37.032 T 10-11-2016 IPR016709 Uncharacterised protein family UPF0336 A4G23_RS16295 f6443ea89d7cf14ef787277a653f39b1 151 SUPERFAMILY SSF54637 7 148 2.22E-39 T 10-11-2016 IPR029069 HotDog domain A4G23_RS16295 f6443ea89d7cf14ef787277a653f39b1 151 Gene3D G3DSA:3.10.129.10 1 149 1.7E-38 T 10-11-2016 IPR029069 HotDog domain A4G23_RS16295 f6443ea89d7cf14ef787277a653f39b1 151 PIRSF PIRSF018072 1 151 5.1E-60 T 10-11-2016 IPR016709 Uncharacterised protein family UPF0336 A4G23_RS26500 6e9b9a25e0a1057e8a77ccf47ebbcab8 248 Pfam PF04865 Baseplate J-like protein 6 153 1.1E-7 T 10-11-2016 IPR006949 Baseplate protein J-like A4G23_RS26455 64189ffb41d090e261532c96588065cf 754 Pfam PF04984 Phage tail sheath protein 1 746 8.1E-69 T 10-11-2016 IPR007067 Tail sheath protein A4G23_RS09585 487f4e56a9aca04e393d41f5440751ae 98 SUPERFAMILY SSF46785 19 90 2.42E-18 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS09585 487f4e56a9aca04e393d41f5440751ae 98 Gene3D G3DSA:1.10.10.10 21 91 1.5E-21 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS09585 487f4e56a9aca04e393d41f5440751ae 98 Pfam PF00392 Bacterial regulatory proteins, gntR family 26 88 5.6E-17 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS09585 487f4e56a9aca04e393d41f5440751ae 98 SMART SM00345 29 88 7.6E-17 T 10-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4G23_RS01100 d90a6121fbdb0314eaf96e51370f7cce 112 Pfam PF11338 Protein of unknown function (DUF3140) 14 102 1.8E-27 T 10-11-2016 IPR021487 Protein of unknown function DUF3140 A4G23_RS08155 5d704cd76e139701f3f38032d42bd293 691 Gene3D G3DSA:3.40.50.2000 261 400 6.1E-22 T 10-11-2016 A4G23_RS08155 5d704cd76e139701f3f38032d42bd293 691 Pfam PF00534 Glycosyl transferases group 1 288 421 1.7E-27 T 10-11-2016 IPR001296 Glycosyl transferase, family 1 A4G23_RS08155 5d704cd76e139701f3f38032d42bd293 691 SUPERFAMILY SSF53756 180 437 1.12E-55 T 10-11-2016 A4G23_RS08155 5d704cd76e139701f3f38032d42bd293 691 Pfam PF13439 Glycosyltransferase Family 4 141 273 8.3E-17 T 10-11-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A4G23_RS26485 ab0a64c9d8859b7c1ab2620f233687c0 393 SUPERFAMILY SSF69279 16 194 3.91E-12 T 10-11-2016 A4G23_RS26280 d791728afb9e0e66d93278b7195ab174 1138 SUPERFAMILY SSF158745 734 935 2.22E-19 T 10-11-2016 A4G23_RS26280 d791728afb9e0e66d93278b7195ab174 1138 SUPERFAMILY SSF158745 1011 1132 1.7E-7 T 10-11-2016 A4G23_RS26280 d791728afb9e0e66d93278b7195ab174 1138 Pfam PF13575 Domain of unknown function (DUF4135) 267 638 1.3E-117 T 10-11-2016 IPR025410 Domain of unknown function DUF4135 A4G23_RS26280 d791728afb9e0e66d93278b7195ab174 1138 TIGRFAM TIGR03897 lanti_2_LanM: type 2 lantibiotic biosynthesis protein LanM 201 935 3.6E-177 T 10-11-2016 IPR017146 Type 2 lantibiotic biosynthesis protein LanM A4G23_RS26280 d791728afb9e0e66d93278b7195ab174 1138 SMART SM01260 757 1131 1.7E-20 T 10-11-2016 IPR007822 Lanthionine synthetase C-like A4G23_RS26280 d791728afb9e0e66d93278b7195ab174 1138 Pfam PF05147 Lanthionine synthetase C-like protein 1001 1131 8.0E-8 T 10-11-2016 IPR007822 Lanthionine synthetase C-like A4G23_RS17650 7133ce97961c90dbb9db311060714ff6 66 Pfam PF04024 PspC domain 4 58 2.0E-16 T 10-11-2016 IPR007168 Phage shock protein, PspC, N-terminal A4G23_RS04850 f5cac451c3f36bcfe462352d7a88542d 228 Hamap MF_00238 Cytidylate kinase [cmk]. 8 224 30.395 T 10-11-2016 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 A4G23_RS04850 f5cac451c3f36bcfe462352d7a88542d 228 SUPERFAMILY SSF52540 7 223 1.54E-35 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS04850 f5cac451c3f36bcfe462352d7a88542d 228 TIGRFAM TIGR00017 cmk: cytidylate kinase 8 218 1.2E-61 T 10-11-2016 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 A4G23_RS04850 f5cac451c3f36bcfe462352d7a88542d 228 Pfam PF02224 Cytidylate kinase 10 220 1.1E-65 T 10-11-2016 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 A4G23_RS04850 f5cac451c3f36bcfe462352d7a88542d 228 Gene3D G3DSA:3.40.50.300 7 220 5.3E-69 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS00020 7b9e70fb9b2551ca3c4b53c8c682d735 342 Gene3D G3DSA:3.40.50.300 79 205 3.3E-7 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS00020 7b9e70fb9b2551ca3c4b53c8c682d735 342 Pfam PF05621 Bacterial TniB protein 67 311 4.4E-22 T 10-11-2016 IPR008868 Bacterial TniB A4G23_RS00020 7b9e70fb9b2551ca3c4b53c8c682d735 342 SUPERFAMILY SSF52540 48 211 1.05E-8 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS03625 b07830280f12298e3bd2818c5f6eb1b8 666 Pfam PF02618 YceG-like family 358 656 3.2E-59 T 10-11-2016 IPR003770 Uncharacterised protein family UPF0755, YceG-like A4G23_RS03625 b07830280f12298e3bd2818c5f6eb1b8 666 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 353 659 9.6E-38 T 10-11-2016 IPR003770 Uncharacterised protein family UPF0755, YceG-like A4G23_RS14030 55ff689ffae4d03755170326cdd088cd 1200 Pfam PF02514 CobN/Magnesium Chelatase 100 1177 0.0 T 10-11-2016 IPR003672 CobN/magnesium chelatase GO:0009058 A4G23_RS14030 55ff689ffae4d03755170326cdd088cd 1200 TIGRFAM TIGR02257 cobalto_cobN: cobaltochelatase, CobN subunit 45 1191 0.0 T 10-11-2016 IPR011953 Cobaltochelatase, CobN subunit GO:0009236|GO:0051116 A4G23_RS03530 149017137b9c89687a41c714180b3840 107 SUPERFAMILY SSF46946 56 102 1.53E-7 T 10-11-2016 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 A4G23_RS03530 149017137b9c89687a41c714180b3840 107 Gene3D G3DSA:1.10.8.50 50 103 7.3E-14 T 10-11-2016 A4G23_RS14400 390e098b6aa8c31184f939cb8f0e8f68 305 Pfam PF04893 Yip1 domain 141 296 4.2E-12 T 10-11-2016 IPR006977 Yip1 domain GO:0016020 A4G23_RS23035 004a036df534726a9b3729462ff1dcca 156 Gene3D G3DSA:3.40.50.620 68 154 3.8E-12 T 10-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4G23_RS23035 004a036df534726a9b3729462ff1dcca 156 SUPERFAMILY SSF52402 78 153 2.16E-19 T 10-11-2016 A4G23_RS26315 efbc0ba907fe7f0b94858d0e4b416be9 825 Pfam PF04738 Lantibiotic dehydratase, C terminus 112 421 6.2E-30 T 10-11-2016 IPR006827 Lantibiotic dehydratase, C-terminal A4G23_RS26315 efbc0ba907fe7f0b94858d0e4b416be9 825 Pfam PF04738 Lantibiotic dehydratase, C terminus 535 774 3.7E-24 T 10-11-2016 IPR006827 Lantibiotic dehydratase, C-terminal A4G23_RS14565 3e3faadacb119cf1bf58014a3f9d74e7 407 Gene3D G3DSA:1.10.630.10 10 407 1.1E-127 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS14565 3e3faadacb119cf1bf58014a3f9d74e7 407 PRINTS PR00359 B-class P450 signature 97 108 5.8E-55 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS14565 3e3faadacb119cf1bf58014a3f9d74e7 407 PRINTS PR00359 B-class P450 signature 301 328 5.8E-55 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS14565 3e3faadacb119cf1bf58014a3f9d74e7 407 PRINTS PR00359 B-class P450 signature 350 359 5.8E-55 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS14565 3e3faadacb119cf1bf58014a3f9d74e7 407 PRINTS PR00359 B-class P450 signature 160 175 5.8E-55 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS14565 3e3faadacb119cf1bf58014a3f9d74e7 407 PRINTS PR00359 B-class P450 signature 143 159 5.8E-55 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS14565 3e3faadacb119cf1bf58014a3f9d74e7 407 PRINTS PR00359 B-class P450 signature 284 295 5.8E-55 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS14565 3e3faadacb119cf1bf58014a3f9d74e7 407 PRINTS PR00359 B-class P450 signature 329 344 5.8E-55 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS14565 3e3faadacb119cf1bf58014a3f9d74e7 407 PRINTS PR00359 B-class P450 signature 203 225 5.8E-55 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS14565 3e3faadacb119cf1bf58014a3f9d74e7 407 PRINTS PR00359 B-class P450 signature 359 370 5.8E-55 T 10-11-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A4G23_RS14565 3e3faadacb119cf1bf58014a3f9d74e7 407 Pfam PF00067 Cytochrome P450 284 379 1.6E-15 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS14565 3e3faadacb119cf1bf58014a3f9d74e7 407 SUPERFAMILY SSF48264 16 407 3.67E-95 T 10-11-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A4G23_RS14565 3e3faadacb119cf1bf58014a3f9d74e7 407 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 352 361 - T 10-11-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A4G23_RS26105 52cabc16ffce6249b6358aa4f416462c 317 ProSitePatterns PS00659 Glycosyl hydrolases family 5 signature. 135 144 - T 10-11-2016 IPR018087 Glycoside hydrolase, family 5, conserved site GO:0004553|GO:0005975 A4G23_RS26105 52cabc16ffce6249b6358aa4f416462c 317 Gene3D G3DSA:3.20.20.80 6 309 1.3E-87 T 10-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 A4G23_RS26105 52cabc16ffce6249b6358aa4f416462c 317 SUPERFAMILY SSF51445 6 313 1.59E-74 T 10-11-2016 IPR017853 Glycoside hydrolase superfamily A4G23_RS26105 52cabc16ffce6249b6358aa4f416462c 317 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 22 272 8.6E-45 T 10-11-2016 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 A4G23_RS00555 f91fecc7be46a673fbccbeb5a98ebf59 326 Gene3D G3DSA:3.90.550.10 2 138 1.1E-22 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS00555 f91fecc7be46a673fbccbeb5a98ebf59 326 Pfam PF00535 Glycosyl transferase family 2 5 166 7.4E-33 T 10-11-2016 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A4G23_RS00555 f91fecc7be46a673fbccbeb5a98ebf59 326 SUPERFAMILY SSF53448 2 187 2.0E-37 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS03465 66fc818fe737f9b7576574113862f182 125 SUPERFAMILY SSF55874 26 112 2.46E-9 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS03465 66fc818fe737f9b7576574113862f182 125 Gene3D G3DSA:3.30.565.10 28 116 6.1E-6 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS03465 66fc818fe737f9b7576574113862f182 125 Pfam PF13581 Histidine kinase-like ATPase domain 10 116 4.5E-10 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS22160 3c33f9439a69dd119eca355538779367 202 Pfam PF07690 Major Facilitator Superfamily 32 195 7.9E-18 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS22160 3c33f9439a69dd119eca355538779367 202 Gene3D G3DSA:1.20.1250.20 29 197 4.9E-23 T 10-11-2016 A4G23_RS22160 3c33f9439a69dd119eca355538779367 202 SUPERFAMILY SSF103473 29 196 3.79E-24 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS20460 72302d159a025605162268795dc3a90e 235 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 46 217 2.8E-15 T 10-11-2016 IPR015330 DNA primase/polymerase, bifunctional, N-terminal A4G23_RS20460 72302d159a025605162268795dc3a90e 235 SMART SM00943 44 222 1.1E-35 T 10-11-2016 IPR015330 DNA primase/polymerase, bifunctional, N-terminal A4G23_RS25330 24eaf41dbc7eb789c9b91b6bfbc1ce74 429 Gene3D G3DSA:1.20.1090.10 173 355 1.1E-36 T 10-11-2016 A4G23_RS25330 24eaf41dbc7eb789c9b91b6bfbc1ce74 429 Pfam PF01761 3-dehydroquinate synthase 70 323 6.3E-68 T 10-11-2016 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 A4G23_RS25330 24eaf41dbc7eb789c9b91b6bfbc1ce74 429 SUPERFAMILY SSF56796 9 346 1.44E-77 T 10-11-2016 A4G23_RS25330 24eaf41dbc7eb789c9b91b6bfbc1ce74 429 Gene3D G3DSA:3.40.50.1970 3 172 6.9E-46 T 10-11-2016 A4G23_RS23050 86b8f3b946635331149a4d007a8bd1c4 231 Gene3D G3DSA:3.40.50.1000 101 212 5.2E-8 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS23050 86b8f3b946635331149a4d007a8bd1c4 231 Pfam PF03767 HAD superfamily, subfamily IIIB (Acid phosphatase) 63 226 9.0E-26 T 10-11-2016 IPR005519 Acid phosphatase, class B-like A4G23_RS23050 86b8f3b946635331149a4d007a8bd1c4 231 SUPERFAMILY SSF56784 96 216 1.35E-12 T 10-11-2016 IPR023214 HAD-like domain A4G23_RS01375 09ce61b2ed5da30346db094e99a50dc0 131 Pfam PF10025 Uncharacterized conserved protein (DUF2267) 4 119 1.9E-19 T 10-11-2016 IPR018727 Protein of unknown function DUF2267 A4G23_RS10135 1a47a75188add9397d464b28fd384850 236 Pfam PF01066 CDP-alcohol phosphatidyltransferase 45 113 3.0E-11 T 10-11-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A4G23_RS10135 1a47a75188add9397d464b28fd384850 236 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 91 113 - T 10-11-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A4G23_RS21555 7b08f28e97204ca79a3f3257323bf838 221 Pfam PF11361 Protein of unknown function (DUF3159) 13 199 1.0E-55 T 10-11-2016 IPR016566 Uncharacterised conserved protein UCP010219 A4G23_RS21555 7b08f28e97204ca79a3f3257323bf838 221 PIRSF PIRSF010219 1 213 2.9E-80 T 10-11-2016 IPR016566 Uncharacterised conserved protein UCP010219 A4G23_RS15435 0c2f17e50633295632b48dc263c6c5fb 542 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 319 341 3.7E-28 T 10-11-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A4G23_RS15435 0c2f17e50633295632b48dc263c6c5fb 542 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 376 390 3.7E-28 T 10-11-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A4G23_RS15435 0c2f17e50633295632b48dc263c6c5fb 542 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 391 405 3.7E-28 T 10-11-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A4G23_RS15435 0c2f17e50633295632b48dc263c6c5fb 542 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 88 107 3.7E-28 T 10-11-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A4G23_RS15435 0c2f17e50633295632b48dc263c6c5fb 542 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 458 471 3.7E-28 T 10-11-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A4G23_RS15435 0c2f17e50633295632b48dc263c6c5fb 542 SUPERFAMILY SSF56601 46 489 5.96E-92 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS15435 0c2f17e50633295632b48dc263c6c5fb 542 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 75 481 1.7E-99 T 10-11-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A4G23_RS15435 0c2f17e50633295632b48dc263c6c5fb 542 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 49 499 8.6E-130 T 10-11-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A4G23_RS15435 0c2f17e50633295632b48dc263c6c5fb 542 Gene3D G3DSA:3.40.710.10 64 142 2.6E-5 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS15435 0c2f17e50633295632b48dc263c6c5fb 542 Gene3D G3DSA:3.40.710.10 259 500 2.1E-63 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS15585 a25d278cf499e08bdcf1615da5fd8f79 70 Pfam PF12728 Helix-turn-helix domain 14 61 8.4E-14 T 10-11-2016 A4G23_RS15585 a25d278cf499e08bdcf1615da5fd8f79 70 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 14 61 4.8E-21 T 10-11-2016 IPR010093 SinI-like, DNA-binding domain GO:0003677 A4G23_RS15585 a25d278cf499e08bdcf1615da5fd8f79 70 Gene3D G3DSA:1.10.10.10 14 62 3.5E-4 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS15585 a25d278cf499e08bdcf1615da5fd8f79 70 SUPERFAMILY SSF46955 13 62 1.67E-5 T 10-11-2016 IPR009061 Putative DNA-binding domain A4G23_RS14285 66b633804af0b50dcf44235e53e53425 181 Pfam PF13302 Acetyltransferase (GNAT) domain 11 147 6.9E-18 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS14285 66b633804af0b50dcf44235e53e53425 181 Gene3D G3DSA:3.40.630.30 11 173 8.4E-39 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS14285 66b633804af0b50dcf44235e53e53425 181 SUPERFAMILY SSF55729 10 172 1.01E-32 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS09765 32ac5086da04b1e7c377c34325b85825 454 Gene3D G3DSA:3.40.190.10 183 377 2.4E-27 T 10-11-2016 A4G23_RS09765 32ac5086da04b1e7c377c34325b85825 454 SUPERFAMILY SSF53850 53 450 4.92E-51 T 10-11-2016 A4G23_RS09765 32ac5086da04b1e7c377c34325b85825 454 Pfam PF01547 Bacterial extracellular solute-binding protein 66 361 1.5E-25 T 10-11-2016 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 A4G23_RS09765 32ac5086da04b1e7c377c34325b85825 454 Gene3D G3DSA:3.40.190.10 59 182 3.2E-19 T 10-11-2016 A4G23_RS21570 cd52dabf2c12a4aad1798ff46a0474db 688 Pfam PF13520 Amino acid permease 56 464 1.2E-27 T 10-11-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A4G23_RS24690 a87c6b13d610c1713b57b0a967f64f19 335 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 14 259 1.5E-74 T 10-11-2016 IPR014145 DNA ligase D, polymerase domain A4G23_RS24690 a87c6b13d610c1713b57b0a967f64f19 335 Pfam PF01896 DNA primase small subunit 144 255 8.3E-9 T 10-11-2016 IPR002755 DNA primase, small subunit GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69109|Reactome: R-HSA-69166|Reactome: R-HSA-69183 A4G23_RS12280 4be432c20c214ac22f0e093b3100f002 109 Pfam PF10724 Protein of unknown function (DUF2516) 6 91 1.3E-26 T 10-11-2016 IPR019662 Protein of unknown function DUF2516 A4G23_RS12440 f5ccb434db0e6ee24f35b7df8d5ac6b2 229 Pfam PF11209 Protein of unknown function (DUF2993) 20 221 8.6E-31 T 10-11-2016 IPR021373 Protein of unknown function DUF2993 A4G23_RS06310 ccf5d4006bd41f58030a9340ae2a8b32 252 Pfam PF13649 Methyltransferase domain 38 134 1.3E-15 T 10-11-2016 A4G23_RS06310 ccf5d4006bd41f58030a9340ae2a8b32 252 SUPERFAMILY SSF53335 19 205 1.67E-30 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS06310 ccf5d4006bd41f58030a9340ae2a8b32 252 Gene3D G3DSA:3.40.50.150 32 201 6.1E-27 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS10060 9df1bb745351a212b427d8fad7153796 89 ProSitePatterns PS00012 Phosphopantetheine attachment site. 42 57 - T 10-11-2016 IPR006162 Phosphopantetheine attachment site A4G23_RS10060 9df1bb745351a212b427d8fad7153796 89 SUPERFAMILY SSF47336 14 81 1.7E-12 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS10060 9df1bb745351a212b427d8fad7153796 89 Gene3D G3DSA:1.10.1200.10 8 85 1.5E-14 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS10060 9df1bb745351a212b427d8fad7153796 89 Pfam PF00550 Phosphopantetheine attachment site 25 75 1.9E-9 T 10-11-2016 IPR009081 Phosphopantetheine binding ACP domain A4G23_RS01385 d95f1e855a326a191531211f43046190 145 Pfam PF00011 Hsp20/alpha crystallin family 36 134 1.4E-19 T 10-11-2016 IPR002068 Alpha crystallin/Hsp20 domain A4G23_RS01385 d95f1e855a326a191531211f43046190 145 Gene3D G3DSA:2.60.40.790 7 134 9.1E-30 T 10-11-2016 IPR008978 HSP20-like chaperone A4G23_RS01385 d95f1e855a326a191531211f43046190 145 SUPERFAMILY SSF49764 6 134 3.66E-30 T 10-11-2016 IPR008978 HSP20-like chaperone A4G23_RS10470 d7769f6e79be98a824a37a25890fbad6 220 Pfam PF07510 Protein of unknown function (DUF1524) 100 209 4.2E-13 T 10-11-2016 IPR011089 Domain of unknown function DUF1524 A4G23_RS00045 667f49c633533a7e71619fcea63d9d53 504 TIGRFAM TIGR04141 TIGR04141: sporadically distributed protein, TIGR04141 family 6 502 1.0E-85 T 10-11-2016 IPR026487 Sporadically distributed protein CHP04141 A4G23_RS10580 bd7e095be614faf439ee46f61ed7a761 333 Pfam PF00487 Fatty acid desaturase 69 283 9.8E-22 T 10-11-2016 IPR005804 Fatty acid desaturase domain GO:0006629 A4G23_RS10580 bd7e095be614faf439ee46f61ed7a761 333 PRINTS PR00075 Fatty acid desaturase family 1 signature 271 285 1.2E-15 T 10-11-2016 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 Reactome: R-HSA-75105 A4G23_RS10580 bd7e095be614faf439ee46f61ed7a761 333 PRINTS PR00075 Fatty acid desaturase family 1 signature 91 111 1.2E-15 T 10-11-2016 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 Reactome: R-HSA-75105 A4G23_RS10580 bd7e095be614faf439ee46f61ed7a761 333 PRINTS PR00075 Fatty acid desaturase family 1 signature 68 90 1.2E-15 T 10-11-2016 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 Reactome: R-HSA-75105 A4G23_RS10580 bd7e095be614faf439ee46f61ed7a761 333 PRINTS PR00075 Fatty acid desaturase family 1 signature 228 249 1.2E-15 T 10-11-2016 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 Reactome: R-HSA-75105 A4G23_RS15595 ca7fc339a555d33d5c4a8a3cc9c05da1 387 SMART SM00563 174 293 9.6E-17 T 10-11-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 A4G23_RS15595 ca7fc339a555d33d5c4a8a3cc9c05da1 387 Gene3D G3DSA:3.40.1130.10 144 299 8.6E-5 T 10-11-2016 A4G23_RS15595 ca7fc339a555d33d5c4a8a3cc9c05da1 387 SUPERFAMILY SSF69593 125 378 5.1E-34 T 10-11-2016 A4G23_RS15595 ca7fc339a555d33d5c4a8a3cc9c05da1 387 Pfam PF01553 Acyltransferase 159 290 8.2E-17 T 10-11-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 A4G23_RS06640 a850310d7eb77bba4e2f1452e0dae886 221 SUPERFAMILY SSF53335 5 127 7.38E-29 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS06640 a850310d7eb77bba4e2f1452e0dae886 221 Pfam PF08241 Methyltransferase domain 8 108 9.4E-19 T 10-11-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 A4G23_RS06640 a850310d7eb77bba4e2f1452e0dae886 221 Gene3D G3DSA:3.40.50.150 5 125 6.5E-28 T 10-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4G23_RS00805 a8e2cd46ba90187eea4c5c1b1793ce74 145 Pfam PF03994 Domain of Unknown Function (DUF350) 87 144 1.6E-13 T 10-11-2016 IPR007140 Protein of unknown function DUF350 A4G23_RS00805 a8e2cd46ba90187eea4c5c1b1793ce74 145 Pfam PF03994 Domain of Unknown Function (DUF350) 14 68 4.1E-15 T 10-11-2016 IPR007140 Protein of unknown function DUF350 A4G23_RS03970 3e0dbe067896e0f9c829b8a67e52db97 182 SUPERFAMILY SSF48498 97 161 5.93E-8 T 10-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4G23_RS03970 3e0dbe067896e0f9c829b8a67e52db97 182 Gene3D G3DSA:1.10.357.10 5 178 3.5E-27 T 10-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 A4G23_RS03970 3e0dbe067896e0f9c829b8a67e52db97 182 SUPERFAMILY SSF46689 4 64 9.71E-13 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS03970 3e0dbe067896e0f9c829b8a67e52db97 182 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 52 4.7E-10 T 10-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4G23_RS02225 fac198b57bab35a14ee465ecd018bc5b 414 Pfam PF02653 Branched-chain amino acid transport system / permease component 68 402 2.9E-46 T 10-11-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 A4G23_RS09335 10e560e85f4ea427154457d4ffb73945 149 Pfam PF05901 Excalibur calcium-binding domain 113 148 2.0E-13 T 10-11-2016 IPR008613 Excalibur calcium-binding domain A4G23_RS09335 10e560e85f4ea427154457d4ffb73945 149 SMART SM00894 112 148 3.2E-19 T 10-11-2016 IPR008613 Excalibur calcium-binding domain A4G23_RS19620 537385c53aa92a69c75fe08af5572a21 107 Gene3D G3DSA:3.30.750.24 2 99 1.0E-26 T 10-11-2016 IPR002645 STAS domain A4G23_RS19620 537385c53aa92a69c75fe08af5572a21 107 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 2 96 2.0E-16 T 10-11-2016 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 A4G23_RS19620 537385c53aa92a69c75fe08af5572a21 107 SUPERFAMILY SSF52091 2 98 7.65E-22 T 10-11-2016 IPR002645 STAS domain A4G23_RS19620 537385c53aa92a69c75fe08af5572a21 107 Pfam PF13466 STAS domain 10 89 5.2E-15 T 10-11-2016 IPR002645 STAS domain A4G23_RS12635 2b8394f24b9c92ca5624130308d52057 469 SUPERFAMILY SSF52540 40 424 6.74E-34 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS12635 2b8394f24b9c92ca5624130308d52057 469 Gene3D G3DSA:3.40.50.300 73 155 6.9E-13 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS12635 2b8394f24b9c92ca5624130308d52057 469 Gene3D G3DSA:3.40.50.300 251 375 6.9E-13 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS12635 2b8394f24b9c92ca5624130308d52057 469 Pfam PF12846 AAA-like domain 69 349 8.1E-15 T 10-11-2016 A4G23_RS11255 9486f8fbcab29c9a19636ebc12a3feb7 383 Gene3D G3DSA:3.40.50.2000 218 363 1.1E-20 T 10-11-2016 A4G23_RS11255 9486f8fbcab29c9a19636ebc12a3feb7 383 Pfam PF06722 Protein of unknown function (DUF1205) 176 272 1.1E-13 T 10-11-2016 IPR010610 Domain of unknown function DUF1205 A4G23_RS11255 9486f8fbcab29c9a19636ebc12a3feb7 383 SUPERFAMILY SSF53756 1 382 1.38E-63 T 10-11-2016 A4G23_RS11255 9486f8fbcab29c9a19636ebc12a3feb7 383 Gene3D G3DSA:3.40.50.2000 1 217 1.5E-17 T 10-11-2016 A4G23_RS02680 b4b4cfdbcd08148103313bd6a319d4b5 674 Pfam PF03235 Protein of unknown function DUF262 16 217 2.3E-24 T 10-11-2016 IPR004919 Domain of unknown function DUF262 A4G23_RS25435 138d50a8078f3be015527473e028715a 221 SUPERFAMILY SSF52218 13 181 1.32E-39 T 10-11-2016 IPR029039 Flavoprotein-like domain A4G23_RS25435 138d50a8078f3be015527473e028715a 221 Gene3D G3DSA:3.40.50.360 5 191 2.1E-42 T 10-11-2016 IPR029039 Flavoprotein-like domain A4G23_RS25435 138d50a8078f3be015527473e028715a 221 Pfam PF03358 NADPH-dependent FMN reductase 12 158 1.3E-27 T 10-11-2016 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 A4G23_RS20470 76b5c453e05f441c85cadb37975487c1 452 Pfam PF00909 Ammonium Transporter Family 23 420 1.5E-125 T 10-11-2016 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 A4G23_RS20470 76b5c453e05f441c85cadb37975487c1 452 ProSitePatterns PS01219 Ammonium transporters signature. 175 200 - T 10-11-2016 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 A4G23_RS20470 76b5c453e05f441c85cadb37975487c1 452 SUPERFAMILY SSF111352 17 401 5.23E-120 T 10-11-2016 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 A4G23_RS20470 76b5c453e05f441c85cadb37975487c1 452 TIGRFAM TIGR00836 amt: ammonium transporter 20 420 3.5E-134 T 10-11-2016 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 A4G23_RS20470 76b5c453e05f441c85cadb37975487c1 452 Gene3D G3DSA:1.10.3430.10 15 401 9.6E-133 T 10-11-2016 IPR029020 Ammonium/urea transporter A4G23_RS23860 84cf4aace6a400fecf5057869928a755 285 Gene3D G3DSA:1.10.260.40 26 82 1.5E-9 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS23860 84cf4aace6a400fecf5057869928a755 285 Pfam PF13560 Helix-turn-helix domain 29 87 4.0E-13 T 10-11-2016 A4G23_RS23860 84cf4aace6a400fecf5057869928a755 285 SMART SM00530 32 87 4.2E-6 T 10-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4G23_RS23860 84cf4aace6a400fecf5057869928a755 285 SUPERFAMILY SSF47413 27 80 3.66E-9 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS02635 ef96f77fd2449f709c94b0138e7e64b6 452 Gene3D G3DSA:1.25.40.10 243 342 2.6E-8 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS02635 ef96f77fd2449f709c94b0138e7e64b6 452 Gene3D G3DSA:1.25.40.10 377 432 2.6E-8 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS02635 ef96f77fd2449f709c94b0138e7e64b6 452 SUPERFAMILY SSF48452 188 314 3.8E-7 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS02635 ef96f77fd2449f709c94b0138e7e64b6 452 SUPERFAMILY SSF48452 363 403 3.8E-7 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS07870 80253fab9cf2131b97ad840dced9c208 237 Pfam PF14032 PknH-like extracellular domain 51 177 1.2E-8 T 10-11-2016 IPR026954 PknH-like extracellular domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 A4G23_RS11820 445117b99ee8f0596401eb6d65366bcc 70 Pfam PF04149 Domain of unknown function (DUF397) 11 66 3.4E-18 T 10-11-2016 IPR007278 Domain of unknown function DUF397 A4G23_RS00775 762363c6348fe710d3c6ea2018761f60 264 Gene3D G3DSA:3.10.180.10 139 261 1.3E-30 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS00775 762363c6348fe710d3c6ea2018761f60 264 Gene3D G3DSA:3.10.180.10 10 125 2.8E-31 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS00775 762363c6348fe710d3c6ea2018761f60 264 SUPERFAMILY SSF54593 11 188 2.76E-21 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS25820 cfe336f2deeddd05ab60afe958e59ca1 126 Gene3D G3DSA:3.30.750.24 3 103 2.2E-18 T 10-11-2016 IPR002645 STAS domain A4G23_RS25820 cfe336f2deeddd05ab60afe958e59ca1 126 Pfam PF13466 STAS domain 12 92 1.6E-16 T 10-11-2016 IPR002645 STAS domain A4G23_RS25820 cfe336f2deeddd05ab60afe958e59ca1 126 SUPERFAMILY SSF52091 7 100 1.57E-16 T 10-11-2016 IPR002645 STAS domain A4G23_RS07865 6b5e08eefb5d5fa8f8817f972a82cd2e 117 Gene3D G3DSA:3.40.140.10 5 111 7.5E-8 T 10-11-2016 A4G23_RS07865 6b5e08eefb5d5fa8f8817f972a82cd2e 117 SUPERFAMILY SSF53927 12 110 1.28E-10 T 10-11-2016 IPR016193 Cytidine deaminase-like GO:0003824 A4G23_RS21470 3c088de2dbfabea831112b65696316ff 344 Pfam PF11268 Protein of unknown function (DUF3071) 1 168 4.9E-55 T 10-11-2016 IPR021421 Protein of unknown function DUF3071 A4G23_RS02430 5100568bcbe517def03fd3d65891b0d7 767 Pfam PF02687 FtsX-like permease family 637 757 5.1E-6 T 10-11-2016 IPR003838 ABC transporter permease protein domain GO:0016020 A4G23_RS02430 5100568bcbe517def03fd3d65891b0d7 767 Pfam PF02687 FtsX-like permease family 252 369 6.1E-11 T 10-11-2016 IPR003838 ABC transporter permease protein domain GO:0016020 A4G23_RS15695 dd560999ab6f3bcd860774bbb400154d 106 Gene3D G3DSA:3.40.630.30 2 69 1.7E-11 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS15695 dd560999ab6f3bcd860774bbb400154d 106 SUPERFAMILY SSF55729 2 55 4.34E-10 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS15695 dd560999ab6f3bcd860774bbb400154d 106 Pfam PF13302 Acetyltransferase (GNAT) domain 2 52 1.3E-7 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS22830 dced1803b28d007a810c6cb819222239 396 TIGRFAM TIGR01869 casC_Cse4: CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI 5 349 2.6E-85 T 10-11-2016 IPR010148 CRISPR-associated protein, CT1975 A4G23_RS22830 dced1803b28d007a810c6cb819222239 396 Pfam PF09344 CT1975-like protein 6 381 5.5E-126 T 10-11-2016 IPR010148 CRISPR-associated protein, CT1975 A4G23_RS18865 09eac1c56db030dc56f51dc2c042bc75 1018 Pfam PF03699 Uncharacterised protein family (UPF0182) 26 801 1.6E-270 T 10-11-2016 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 A4G23_RS18865 09eac1c56db030dc56f51dc2c042bc75 1018 Hamap MF_01600 UPF0182 protein . 17 893 17.603 T 10-11-2016 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 A4G23_RS14060 28dca84ee60fafc67564f7a642944acd 271 Pfam PF05552 Conserved TM helix 18 64 4.2E-15 T 10-11-2016 IPR008910 Conserved TM helix A4G23_RS26660 f6f5ecac370c0fb20cbc0e4bdffe6a17 422 Pfam PF00144 Beta-lactamase 69 396 3.6E-52 T 10-11-2016 IPR001466 Beta-lactamase-related A4G23_RS26660 f6f5ecac370c0fb20cbc0e4bdffe6a17 422 Gene3D G3DSA:3.40.710.10 62 402 6.7E-68 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS26660 f6f5ecac370c0fb20cbc0e4bdffe6a17 422 SUPERFAMILY SSF56601 70 405 1.51E-65 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS07155 71ca10b2a60a54c604ac764dc0116f1f 356 Gene3D G3DSA:1.50.10.20 265 338 3.5E-14 T 10-11-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A4G23_RS07155 71ca10b2a60a54c604ac764dc0116f1f 356 Gene3D G3DSA:1.50.10.20 23 225 3.5E-14 T 10-11-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A4G23_RS07155 71ca10b2a60a54c604ac764dc0116f1f 356 SUPERFAMILY SSF48208 26 340 1.59E-36 T 10-11-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 A4G23_RS03665 a9f5e2a8f3670a4ccd425448f8bf7669 206 Pfam PF07884 Vitamin K epoxide reductase family 25 157 1.0E-29 T 10-11-2016 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 A4G23_RS03665 a9f5e2a8f3670a4ccd425448f8bf7669 206 SMART SM00756 20 161 5.0E-52 T 10-11-2016 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 A4G23_RS08910 dfbe69a42c16407a667aebfd724e63ae 77 Pfam PF04149 Domain of unknown function (DUF397) 14 67 6.6E-22 T 10-11-2016 IPR007278 Domain of unknown function DUF397 A4G23_RS09085 fb6b508f94f8c86e3aa11d7fce0fc250 292 Pfam PF14435 SUKH-4 immunity protein 9 177 3.0E-18 T 10-11-2016 IPR025851 SUKH-4 immunity protein A4G23_RS09085 fb6b508f94f8c86e3aa11d7fce0fc250 292 Pfam PF14440 Xanthomonas XOO_2897-like deaminase 187 282 1.6E-26 T 10-11-2016 IPR032722 Deaminase, Xanthomonas XOO_2897-like A4G23_RS18660 e40cb4b3d325f27ab35fc21e495fe6cb 75 Pfam PF11305 Protein of unknown function (DUF3107) 1 73 3.2E-31 T 10-11-2016 IPR021456 Protein of unknown function DUF3107 A4G23_RS22750 7dd10d4705b1e1fd966517a6c7246126 1070 PRINTS PR01217 Proline rich extensin signature 742 759 9.8E-9 T 10-11-2016 A4G23_RS22750 7dd10d4705b1e1fd966517a6c7246126 1070 PRINTS PR01217 Proline rich extensin signature 691 712 9.8E-9 T 10-11-2016 A4G23_RS22750 7dd10d4705b1e1fd966517a6c7246126 1070 PRINTS PR01217 Proline rich extensin signature 661 677 9.8E-9 T 10-11-2016 A4G23_RS22750 7dd10d4705b1e1fd966517a6c7246126 1070 PRINTS PR01217 Proline rich extensin signature 826 838 9.8E-9 T 10-11-2016 A4G23_RS22750 7dd10d4705b1e1fd966517a6c7246126 1070 PRINTS PR01217 Proline rich extensin signature 789 814 9.8E-9 T 10-11-2016 A4G23_RS22750 7dd10d4705b1e1fd966517a6c7246126 1070 PRINTS PR01217 Proline rich extensin signature 645 657 9.8E-9 T 10-11-2016 A4G23_RS13680 28c473b53a60d8e231ba64980bed3534 410 Pfam PF07907 YibE/F-like protein 138 376 1.8E-73 T 10-11-2016 IPR012507 YibE/F-like A4G23_RS05465 44ebf7f1b7e557b7d705374483b94180 300 PIRSF PIRSF001365 7 300 9.8E-59 T 10-11-2016 IPR002220 DapA-like GO:0008152|GO:0016829 A4G23_RS05465 44ebf7f1b7e557b7d705374483b94180 300 Gene3D G3DSA:3.20.20.70 8 299 4.9E-74 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS05465 44ebf7f1b7e557b7d705374483b94180 300 Pfam PF00701 Dihydrodipicolinate synthetase family 11 297 8.9E-40 T 10-11-2016 IPR002220 DapA-like GO:0008152|GO:0016829 A4G23_RS05465 44ebf7f1b7e557b7d705374483b94180 300 SMART SM01130 9 299 7.7E-58 T 10-11-2016 IPR002220 DapA-like GO:0008152|GO:0016829 A4G23_RS05465 44ebf7f1b7e557b7d705374483b94180 300 SUPERFAMILY SSF51569 13 298 9.52E-64 T 10-11-2016 A4G23_RS15940 3cd5c65efd6390211718270722860959 133 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 9 84 2.3E-24 T 10-11-2016 IPR025161 Putative transposase IS4/IS5 family A4G23_RS13170 2b9437c35c906dff6cd0b184ae463c24 349 Gene3D G3DSA:3.90.1200.10 122 344 3.4E-20 T 10-11-2016 A4G23_RS13170 2b9437c35c906dff6cd0b184ae463c24 349 SUPERFAMILY SSF56112 17 338 4.37E-41 T 10-11-2016 IPR011009 Protein kinase-like domain A4G23_RS13170 2b9437c35c906dff6cd0b184ae463c24 349 Gene3D G3DSA:3.30.200.20 18 113 5.4E-11 T 10-11-2016 A4G23_RS13170 2b9437c35c906dff6cd0b184ae463c24 349 Pfam PF01636 Phosphotransferase enzyme family 36 287 6.0E-27 T 10-11-2016 IPR002575 Aminoglycoside phosphotransferase A4G23_RS04915 7d2e6896476a0f7ba1d0437e034ebf72 208 SUPERFAMILY SSF55811 9 180 5.15E-44 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS04915 7d2e6896476a0f7ba1d0437e034ebf72 208 Gene3D G3DSA:3.90.79.10 9 182 7.9E-50 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS04915 7d2e6896476a0f7ba1d0437e034ebf72 208 Pfam PF00293 NUDIX domain 48 161 1.5E-16 T 10-11-2016 IPR000086 NUDIX hydrolase domain GO:0016787 A4G23_RS11995 55d9fcaf5e786e001239da074537e34f 91 Gene3D G3DSA:3.10.20.30 3 89 1.1E-30 T 10-11-2016 IPR012675 Beta-grasp domain A4G23_RS11995 55d9fcaf5e786e001239da074537e34f 91 SUPERFAMILY SSF54285 1 91 2.13E-23 T 10-11-2016 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp A4G23_RS11995 55d9fcaf5e786e001239da074537e34f 91 Pfam PF02597 ThiS family 5 91 4.2E-19 T 10-11-2016 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 A4G23_RS12195 a0bfa7561af2171531debebbc32dfcd8 160 SMART SM01058 2 112 1.2E-32 T 10-11-2016 IPR003711 CarD-like/TRCF domain A4G23_RS12195 a0bfa7561af2171531debebbc32dfcd8 160 SUPERFAMILY SSF141259 2 65 3.66E-15 T 10-11-2016 IPR003711 CarD-like/TRCF domain A4G23_RS12195 a0bfa7561af2171531debebbc32dfcd8 160 Pfam PF02559 CarD-like/TRCF domain 3 110 1.4E-15 T 10-11-2016 IPR003711 CarD-like/TRCF domain A4G23_RS24940 170fc62f79c0f3efd6357696a6eb9f57 316 SUPERFAMILY SSF51261 163 309 1.83E-45 T 10-11-2016 IPR011055 Duplicated hybrid motif A4G23_RS24940 170fc62f79c0f3efd6357696a6eb9f57 316 Gene3D G3DSA:3.10.350.10 70 119 6.5E-6 T 10-11-2016 IPR018392 LysM domain A4G23_RS24940 170fc62f79c0f3efd6357696a6eb9f57 316 Pfam PF01551 Peptidase family M23 208 305 7.7E-32 T 10-11-2016 IPR016047 Peptidase M23 A4G23_RS24940 170fc62f79c0f3efd6357696a6eb9f57 316 Gene3D G3DSA:2.70.70.10 166 310 2.9E-45 T 10-11-2016 A4G23_RS25345 4c3504edf6e2200e170f326edb772b48 147 Gene3D G3DSA:1.10.260.40 52 138 4.1E-8 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS05235 06739eaeb0eb16f6d14d1b2cc9c203c2 594 Pfam PF00723 Glycosyl hydrolases family 15 217 584 1.3E-68 T 10-11-2016 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: R-HSA-70221 A4G23_RS05235 06739eaeb0eb16f6d14d1b2cc9c203c2 594 SUPERFAMILY SSF48208 191 588 4.67E-104 T 10-11-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 A4G23_RS05235 06739eaeb0eb16f6d14d1b2cc9c203c2 594 Gene3D G3DSA:1.50.10.10 212 589 8.0E-82 T 10-11-2016 IPR012341 Six-hairpin glycosidase GO:0003824 A4G23_RS11200 bd0df80dfe2eff084bcce49869a9228e 382 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 247 3.6E-40 T 10-11-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 A4G23_RS11200 bd0df80dfe2eff084bcce49869a9228e 382 SUPERFAMILY SSF51735 4 324 9.24E-53 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS11200 bd0df80dfe2eff084bcce49869a9228e 382 Gene3D G3DSA:3.40.50.720 6 320 8.1E-44 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS21550 bbd1d590e64d96cdded5f3c503fe5eb8 116 PIRSF PIRSF006910 1 113 3.1E-48 T 10-11-2016 IPR016499 Nucleic acid binding protein, Rv2694c, predicted A4G23_RS21550 bbd1d590e64d96cdded5f3c503fe5eb8 116 Gene3D G3DSA:2.40.50.140 27 110 2.1E-8 T 10-11-2016 IPR012340 Nucleic acid-binding, OB-fold A4G23_RS20550 c38961aa626749893b92194c5e5da56a 102 Pfam PF10611 Protein of unknown function (DUF2469) 1 100 1.8E-52 T 10-11-2016 IPR019592 Protein of unknown function DUF2469 A4G23_RS19710 bb4787bbaaaa0b06ce8b52cfd63ec2fd 212 Gene3D G3DSA:3.60.160.10 9 207 3.0E-44 T 10-11-2016 IPR002838 Mitochondrial biogenesis protein AIM24 A4G23_RS19710 bb4787bbaaaa0b06ce8b52cfd63ec2fd 212 Pfam PF01987 Mitochondrial biogenesis AIM24 5 202 3.1E-35 T 10-11-2016 IPR002838 Mitochondrial biogenesis protein AIM24 A4G23_RS19710 bb4787bbaaaa0b06ce8b52cfd63ec2fd 212 SUPERFAMILY SSF51219 8 207 2.17E-46 T 10-11-2016 IPR016031 Tryptophan RNA-binding attenuator protein-like domain A4G23_RS11230 9dea2a4d0e98155ff0945624f1ecb648 378 Pfam PF05141 Pyoverdine/dityrosine biosynthesis protein 51 301 9.5E-76 T 10-11-2016 IPR007817 Pyoverdine biosynthesis A4G23_RS02465 59a210f3008eb86c2cdfc391ced387b6 294 SUPERFAMILY SSF161098 20 294 2.8E-67 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS02465 59a210f3008eb86c2cdfc391ced387b6 294 Gene3D G3DSA:1.10.3720.10 15 282 9.7E-61 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS02465 59a210f3008eb86c2cdfc391ced387b6 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 280 2.5E-17 T 10-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A4G23_RS20225 2d7f73f211986df77bc6aaacba1b97ed 65 Pfam PF13822 Acyl-CoA carboxylase epsilon subunit 6 63 4.3E-15 T 10-11-2016 IPR032716 Acyl-CoA carboxylase epsilon subunit A4G23_RS03140 9a3700b3dca63ed6aeb2f77ad3a1a54e 174 Pfam PF00293 NUDIX domain 39 108 1.7E-11 T 10-11-2016 IPR000086 NUDIX hydrolase domain GO:0016787 A4G23_RS03140 9a3700b3dca63ed6aeb2f77ad3a1a54e 174 ProSitePatterns PS00893 Nudix box signature. 75 96 - T 10-11-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A4G23_RS03140 9a3700b3dca63ed6aeb2f77ad3a1a54e 174 Gene3D G3DSA:3.90.79.10 19 115 6.7E-16 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS03140 9a3700b3dca63ed6aeb2f77ad3a1a54e 174 SUPERFAMILY SSF55811 7 120 5.01E-19 T 10-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 A4G23_RS11775 584244858f563d330b92ec6c405d5a9f 239 Pfam PF03932 CutC family 6 204 6.3E-24 T 10-11-2016 IPR005627 Copper homeostasis protein CutC GO:0005507|GO:0055070 Reactome: R-HSA-936837 A4G23_RS11775 584244858f563d330b92ec6c405d5a9f 239 SUPERFAMILY SSF110395 6 228 5.1E-46 T 10-11-2016 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 A4G23_RS11775 584244858f563d330b92ec6c405d5a9f 239 Gene3D G3DSA:3.20.20.380 5 215 2.3E-50 T 10-11-2016 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 A4G23_RS14895 5a8ee9c187741eb110d5d8e6af3c363c 272 Gene3D G3DSA:1.10.3290.10 107 249 1.3E-4 T 10-11-2016 IPR003812 Fido domain A4G23_RS11385 68d3090ad70c0f2ca4fbe0d406df84ab 275 SUPERFAMILY SSF54593 156 273 3.82E-12 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS11385 68d3090ad70c0f2ca4fbe0d406df84ab 275 Gene3D G3DSA:3.10.180.10 149 273 6.7E-28 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS11385 68d3090ad70c0f2ca4fbe0d406df84ab 275 Gene3D G3DSA:3.10.180.10 20 135 1.2E-30 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS11385 68d3090ad70c0f2ca4fbe0d406df84ab 275 SUPERFAMILY SSF54593 26 197 8.46E-18 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS10525 5a463ac29ed17e4109a4761fa1121bbb 179 Pfam PF14431 YwqJ-like deaminase 41 167 7.3E-22 T 10-11-2016 IPR025968 YwqJ-like deaminase A4G23_RS16230 d75450bde12e76ef9ddc75d87d0460ec 529 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 24 521 15.185 T 10-11-2016 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 A4G23_RS16230 d75450bde12e76ef9ddc75d87d0460ec 529 Pfam PF00361 Proton-conducting membrane transporter 148 447 2.3E-52 T 10-11-2016 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS20210 05b570460f44b59c89a5ad2257c1bc2c 385 Pfam PF01757 Acyltransferase family 26 357 1.2E-25 T 10-11-2016 IPR002656 Acyltransferase 3 GO:0016747 A4G23_RS05600 42585ea29c7f9f5a7f9f9b5155632afc 320 Pfam PF02628 Cytochrome oxidase assembly protein 22 291 1.3E-18 T 10-11-2016 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 A4G23_RS01175 b5e1202cd5acc4d7aeb938fc0d63a6c5 69 Pfam PF17196 Protein of unknown function (DUF5133) 1 65 1.1E-22 T 10-11-2016 IPR033457 Protein of unknown function DUF5133 A4G23_RS24100 0261a2395bbe00c4c33ebae35b5801e9 280 Pfam PF00795 Carbon-nitrogen hydrolase 6 261 2.3E-63 T 10-11-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 A4G23_RS24100 0261a2395bbe00c4c33ebae35b5801e9 280 SUPERFAMILY SSF56317 3 277 1.07E-78 T 10-11-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 A4G23_RS24100 0261a2395bbe00c4c33ebae35b5801e9 280 Gene3D G3DSA:3.60.110.10 4 278 7.8E-85 T 10-11-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 A4G23_RS18285 0762efe91286f5403d344405d500de83 411 Pfam PF13742 OB-fold nucleic acid binding domain 12 105 4.4E-17 T 10-11-2016 IPR025824 OB-fold nucleic acid binding domain GO:0003676 A4G23_RS18285 0762efe91286f5403d344405d500de83 411 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 13 398 3.6E-121 T 10-11-2016 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 A4G23_RS18285 0762efe91286f5403d344405d500de83 411 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 5 401 25.234 T 10-11-2016 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 A4G23_RS18285 0762efe91286f5403d344405d500de83 411 Pfam PF02601 Exonuclease VII, large subunit 129 333 1.7E-61 T 10-11-2016 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 A4G23_RS18285 0762efe91286f5403d344405d500de83 411 Pfam PF02601 Exonuclease VII, large subunit 334 397 6.9E-9 T 10-11-2016 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 A4G23_RS27085 7e44df82c704a1264f6fae7c3a263445 221 Pfam PF01553 Acyltransferase 27 147 5.8E-20 T 10-11-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 A4G23_RS27085 7e44df82c704a1264f6fae7c3a263445 221 SUPERFAMILY SSF69593 28 205 1.57E-26 T 10-11-2016 A4G23_RS27085 7e44df82c704a1264f6fae7c3a263445 221 SMART SM00563 30 151 2.8E-23 T 10-11-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 A4G23_RS27085 7e44df82c704a1264f6fae7c3a263445 221 Gene3D G3DSA:3.40.1130.10 30 157 9.4E-14 T 10-11-2016 A4G23_RS15685 3c655bb3f8ae25be42dcbb7cbc93e4e4 181 Pfam PF04978 Protein of unknown function (DUF664) 20 176 2.1E-48 T 10-11-2016 IPR007061 Protein of unknown function DUF664 A4G23_RS15685 3c655bb3f8ae25be42dcbb7cbc93e4e4 181 Gene3D G3DSA:1.20.120.450 10 178 8.1E-45 T 10-11-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase A4G23_RS15685 3c655bb3f8ae25be42dcbb7cbc93e4e4 181 SUPERFAMILY SSF109854 13 175 1.48E-41 T 10-11-2016 A4G23_RS11695 69ddff6f384464ca2f75b4ecbdcb696d 416 Gene3D G3DSA:3.20.20.30 1 279 1.5E-87 T 10-11-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4G23_RS11695 69ddff6f384464ca2f75b4ecbdcb696d 416 Gene3D G3DSA:3.20.20.30 313 373 1.5E-87 T 10-11-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4G23_RS11695 69ddff6f384464ca2f75b4ecbdcb696d 416 Pfam PF00296 Luciferase-like monooxygenase 19 342 1.3E-53 T 10-11-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4G23_RS11695 69ddff6f384464ca2f75b4ecbdcb696d 416 SUPERFAMILY SSF51679 1 372 6.28E-73 T 10-11-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4G23_RS14580 83d9dd221034895b8261bbb7b2f80670 153 SUPERFAMILY SSF46785 3 106 3.78E-14 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS14580 83d9dd221034895b8261bbb7b2f80670 153 Pfam PF12802 MarR family 16 75 7.6E-10 T 10-11-2016 A4G23_RS14580 83d9dd221034895b8261bbb7b2f80670 153 Gene3D G3DSA:1.10.10.10 3 79 1.7E-15 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS22895 4acd5027e3fc304b69e039ede2412d8d 513 PIRSF PIRSF006060 16 510 5.1E-91 T 10-11-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A4G23_RS22895 4acd5027e3fc304b69e039ede2412d8d 513 Pfam PF13520 Amino acid permease 39 466 2.1E-51 T 10-11-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A4G23_RS17215 bb1cab922d5b5bb560fbc7a0d5066940 66 Pfam PF04149 Domain of unknown function (DUF397) 12 66 8.4E-21 T 10-11-2016 IPR007278 Domain of unknown function DUF397 A4G23_RS24205 4d96dbe0cd24bf0e3aaf1e12d4ebcf84 251 Pfam PF02754 Cysteine-rich domain 3 83 2.6E-15 T 10-11-2016 IPR004017 Cysteine-rich domain A4G23_RS24205 4d96dbe0cd24bf0e3aaf1e12d4ebcf84 251 Pfam PF02754 Cysteine-rich domain 138 222 1.8E-15 T 10-11-2016 IPR004017 Cysteine-rich domain A4G23_RS15420 cfcdcc7d53394e96f7eb91230cb03a33 111 Pfam PF11774 Lsr2 2 109 1.2E-40 T 10-11-2016 IPR024412 Lsr2 A4G23_RS15420 cfcdcc7d53394e96f7eb91230cb03a33 111 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 1 110 9.0E-36 T 10-11-2016 IPR024412 Lsr2 A4G23_RS04865 f2a4b712eae6f0629fea458e6acb8758 249 Pfam PF10127 Predicted nucleotidyltransferase 6 242 1.1E-49 T 10-11-2016 IPR018775 Nucleotidyltransferase, predicted A4G23_RS03020 7d2188a0f115afcfd2efe6f5352312e1 266 Pfam PF02517 CAAX protease self-immunity 158 247 6.8E-15 T 10-11-2016 IPR003675 CAAX amino terminal protease GO:0016020 A4G23_RS18110 155910753dfd6658a79a26d237f496d9 127 Pfam PF07811 TadE-like protein 14 56 1.6E-7 T 10-11-2016 IPR012495 TadE-like A4G23_RS16415 ad1511081b2f227b6b50d38654d80f4e 311 Pfam PF05709 Phage tail protein 179 307 1.6E-7 T 10-11-2016 IPR008841 Siphovirus-type tail component A4G23_RS25080 b04321db06933c0fe681eec3845ef205 236 SUPERFAMILY SSF51735 2 218 2.52E-37 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS25080 b04321db06933c0fe681eec3845ef205 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 8.2E-9 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS25080 b04321db06933c0fe681eec3845ef205 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 8.2E-9 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS25080 b04321db06933c0fe681eec3845ef205 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 8.2E-9 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS25080 b04321db06933c0fe681eec3845ef205 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 8.2E-9 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS25080 b04321db06933c0fe681eec3845ef205 236 Gene3D G3DSA:3.40.50.720 2 218 4.0E-34 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS25080 b04321db06933c0fe681eec3845ef205 236 Pfam PF00106 short chain dehydrogenase 8 186 1.2E-23 T 10-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR A4G23_RS25640 298c1b5c30db25dd9666aefd2f196570 66 Pfam PF04149 Domain of unknown function (DUF397) 10 61 5.2E-22 T 10-11-2016 IPR007278 Domain of unknown function DUF397 A4G23_RS07590 fd678c335a873421c2183b69f26377b9 557 Pfam PF05141 Pyoverdine/dityrosine biosynthesis protein 145 254 1.1E-12 T 10-11-2016 IPR007817 Pyoverdine biosynthesis A4G23_RS02510 d74bd6a9614b8e28e2dba0ee8c4fb049 318 TIGRFAM TIGR03891 thiopep_ocin: thiopeptide-type bacteriocin biosynthesis domain 71 310 2.9E-19 T 10-11-2016 IPR023809 Thiopeptide-type bacteriocin biosynthesis domain A4G23_RS02510 d74bd6a9614b8e28e2dba0ee8c4fb049 318 Pfam PF14028 Lantibiotic biosynthesis dehydratase C-term 73 313 4.5E-12 T 10-11-2016 IPR023809 Thiopeptide-type bacteriocin biosynthesis domain A4G23_RS14920 9cf9b0e67e0cc66a859bd80e09206329 243 Pfam PF00482 Type II secretion system (T2SS), protein F 109 231 2.1E-18 T 10-11-2016 IPR018076 Type II secretion system F domain A4G23_RS23285 7e5e6545df883c0a4cb957252cdd2e82 137 SUPERFAMILY SSF88723 8 124 8.5E-10 T 10-11-2016 IPR029060 PIN domain-like A4G23_RS23285 7e5e6545df883c0a4cb957252cdd2e82 137 Gene3D G3DSA:3.40.50.1010 7 123 3.1E-6 T 10-11-2016 IPR029060 PIN domain-like A4G23_RS09375 9eb9dcd9dff3b65e099f8043a5e9542a 106 SUPERFAMILY SSF103481 6 104 8.37E-17 T 10-11-2016 A4G23_RS09375 9eb9dcd9dff3b65e099f8043a5e9542a 106 Pfam PF00893 Small Multidrug Resistance protein 1 93 2.5E-27 T 10-11-2016 IPR000390 Small multidrug resistance protein family GO:0016021 A4G23_RS24715 30fd91829281d314f968193f3bd1647d 138 Pfam PF04686 Streptomyces sporulation and cell division protein, SsgA 23 120 1.6E-32 T 10-11-2016 IPR006776 Sporulation-specific cell division protein SsgB GO:0051301 A4G23_RS11025 55a624233bdcdee41e6dc1e20e412e69 344 Pfam PF06626 Protein of unknown function (DUF1152) 3 268 1.1E-75 T 10-11-2016 IPR010581 Protein of unknown function DUF1152 A4G23_RS04780 a86765dd138c79402afe7635cb2aa23f 77 Pfam PF11720 Peptidase inhibitor I78 family 31 68 2.7E-5 T 10-11-2016 IPR021719 Proteinase inhibitor I78 A4G23_RS09010 f3904c2a9ecb16d66a60879ec2a45813 571 Pfam PF06276 Ferric iron reductase FhuF-like transporter 390 546 1.8E-38 T 10-11-2016 IPR022770 Ferric iron reductase FhuF domain A4G23_RS09010 f3904c2a9ecb16d66a60879ec2a45813 571 Pfam PF04183 IucA / IucC family 118 368 2.1E-80 T 10-11-2016 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0015343|GO:0019290 A4G23_RS00800 8406dda9d11e7d5e660c230cf459be02 134 Pfam PF14042 Domain of unknown function (DUF4247) 39 129 2.6E-14 T 10-11-2016 IPR025341 Protein of unknown function DUF4247 A4G23_RS06395 3f082f7f67e3d65112102bad32759ac8 89 Pfam PF04324 BFD-like [2Fe-2S] binding domain 5 53 3.8E-11 T 10-11-2016 IPR007419 BFD-like [2Fe-2S]-binding domain A4G23_RS24315 77cb33d8c994e6b74199b848a37bcee8 137 Gene3D G3DSA:3.30.1330.40 5 134 1.3E-43 T 10-11-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like A4G23_RS24315 77cb33d8c994e6b74199b848a37bcee8 137 SUPERFAMILY SSF55298 6 134 5.97E-35 T 10-11-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like A4G23_RS24315 77cb33d8c994e6b74199b848a37bcee8 137 Pfam PF01042 Endoribonuclease L-PSP 16 130 5.9E-29 T 10-11-2016 IPR006175 YjgF/YER057c/UK114 family A4G23_RS20940 701178f32c89031cf80af14919292c67 395 Pfam PF11203 Putative type VII ESX secretion system translocon, EccE 187 296 4.5E-28 T 10-11-2016 IPR021368 Type VII secretion system protein EccE A4G23_RS20940 701178f32c89031cf80af14919292c67 395 TIGRFAM TIGR03923 T7SS_EccE: type VII secretion protein EccE 5 394 4.3E-63 T 10-11-2016 IPR021368 Type VII secretion system protein EccE A4G23_RS04490 2197a2e5d077302610abc00763f94490 309 Pfam PF00849 RNA pseudouridylate synthase 105 252 1.0E-17 T 10-11-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4G23_RS04490 2197a2e5d077302610abc00763f94490 309 SUPERFAMILY SSF55120 90 302 1.12E-46 T 10-11-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4G23_RS04490 2197a2e5d077302610abc00763f94490 309 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 143 157 - T 10-11-2016 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4G23_RS19395 cc25bc98526a2151b60c93a6433feb62 293 Gene3D G3DSA:3.40.50.720 172 287 2.2E-4 T 10-11-2016 IPR016040 NAD(P)-binding domain A4G23_RS19395 cc25bc98526a2151b60c93a6433feb62 293 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 13 255 3.4E-82 T 10-11-2016 IPR014145 DNA ligase D, polymerase domain A4G23_RS11465 4d668fda1b294e0b054535c9060933cb 460 Gene3D G3DSA:1.25.40.10 217 421 5.5E-6 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS22985 9ca21b7f2c4ceb63054c9176ac88d134 224 SUPERFAMILY SSF102462 142 223 1.2E-16 T 10-11-2016 IPR023476 Peptidyl-tRNA hydrolase II domain MetaCyc: PWY-6308 A4G23_RS22985 9ca21b7f2c4ceb63054c9176ac88d134 224 Gene3D G3DSA:3.40.1490.10 142 223 1.2E-12 T 10-11-2016 IPR023476 Peptidyl-tRNA hydrolase II domain MetaCyc: PWY-6308 A4G23_RS09465 cf30d82e71c531030d5a2207064fba25 470 Pfam PF00324 Amino acid permease 29 457 2.5E-109 T 10-11-2016 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 A4G23_RS09465 cf30d82e71c531030d5a2207064fba25 470 PIRSF PIRSF006060 2 468 8.0E-63 T 10-11-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A4G23_RS09465 cf30d82e71c531030d5a2207064fba25 470 ProSitePatterns PS00218 Amino acid permeases signature. 53 83 - T 10-11-2016 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 A4G23_RS14945 ce0c99510890ed57f6b481feb04716e8 152 Pfam PF13581 Histidine kinase-like ATPase domain 8 143 2.2E-30 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS02995 ddce2c76887d651d40f5ab0b5ebd6aa0 228 Gene3D G3DSA:2.30.110.10 9 200 1.4E-77 T 10-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 A4G23_RS02995 ddce2c76887d651d40f5ab0b5ebd6aa0 228 SUPERFAMILY SSF50475 13 200 1.23E-60 T 10-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 A4G23_RS02995 ddce2c76887d651d40f5ab0b5ebd6aa0 228 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 31 179 9.1E-50 T 10-11-2016 IPR024747 Pyridoxamine 5'-phosphate oxidase-related A4G23_RS18135 5d854f02fe023016983193f1b3d9c14c 210 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 1 38 4.4E-6 T 10-11-2016 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal A4G23_RS03295 072c95bd84a59a6970bb47df183567d5 424 Pfam PF13556 PucR C-terminal helix-turn-helix domain 359 416 4.5E-19 T 10-11-2016 IPR025736 PucR C-terminal helix-turn-helix domain A4G23_RS11690 9fda7bc4ba7090f493e35145a3319029 752 SUPERFAMILY SSF69318 446 725 1.01E-19 T 10-11-2016 A4G23_RS11690 9fda7bc4ba7090f493e35145a3319029 752 Gene3D G3DSA:2.115.10.10 501 652 9.3E-16 T 10-11-2016 IPR023294 Tachylectin 2 A4G23_RS11690 9fda7bc4ba7090f493e35145a3319029 752 Gene3D G3DSA:2.115.10.10 653 727 5.8E-7 T 10-11-2016 IPR023294 Tachylectin 2 A4G23_RS03770 8345298b38ea7c41b793de048d87d8f9 223 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 69 91 - T 10-11-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A4G23_RS03770 8345298b38ea7c41b793de048d87d8f9 223 Pfam PF01066 CDP-alcohol phosphatidyltransferase 27 91 1.3E-9 T 10-11-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A4G23_RS23270 73b2f2ff687b908a032b61199bc1d792 934 Pfam PF02687 FtsX-like permease family 802 922 1.7E-7 T 10-11-2016 IPR003838 ABC transporter permease protein domain GO:0016020 A4G23_RS21610 3213ed6789574a36548e5c6bc546f2cd 471 SUPERFAMILY SSF102114 157 419 1.69E-11 T 10-11-2016 A4G23_RS21610 3213ed6789574a36548e5c6bc546f2cd 471 Gene3D G3DSA:3.20.20.70 158 397 5.3E-7 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS00515 7b4d77552030cf78fcb656ec5f01d083 61 Pfam PF00741 Gas vesicle protein 9 47 4.6E-14 T 10-11-2016 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 A4G23_RS13500 a25e5510fbdf823d0d08b298a7616998 311 Gene3D G3DSA:3.40.50.300 32 279 2.0E-74 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS13500 a25e5510fbdf823d0d08b298a7616998 311 Pfam PF13614 AAA domain 30 207 1.1E-57 T 10-11-2016 IPR025669 AAA domain A4G23_RS13500 a25e5510fbdf823d0d08b298a7616998 311 SUPERFAMILY SSF52540 30 279 2.79E-66 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS00530 617f722d3de9f803fb7528dd6afac1be 692 Pfam PF12805 FUSC-like inner membrane protein yccS 79 190 7.1E-6 T 10-11-2016 IPR032692 Integral membrane protein YccS, N-terminal A4G23_RS00530 617f722d3de9f803fb7528dd6afac1be 692 Pfam PF13515 Fusaric acid resistance protein-like 382 503 9.2E-18 T 10-11-2016 A4G23_RS16930 366db30a41865c34e2f23b44b89694ed 134 Pfam PF12680 SnoaL-like domain 30 109 9.6E-9 T 10-11-2016 IPR009959 Polyketide cyclase SnoaL-like domain A4G23_RS16930 366db30a41865c34e2f23b44b89694ed 134 SUPERFAMILY SSF54427 23 132 1.08E-20 T 10-11-2016 IPR032710 NTF2-like domain A4G23_RS16930 366db30a41865c34e2f23b44b89694ed 134 Gene3D G3DSA:3.10.450.50 23 123 9.1E-16 T 10-11-2016 IPR032710 NTF2-like domain A4G23_RS05105 bdbd4617bec12be72b7804bb6d3ccbe7 420 Gene3D G3DSA:1.20.1250.20 233 409 3.1E-12 T 10-11-2016 A4G23_RS05105 bdbd4617bec12be72b7804bb6d3ccbe7 420 SUPERFAMILY SSF103473 218 412 2.09E-39 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS05105 bdbd4617bec12be72b7804bb6d3ccbe7 420 SUPERFAMILY SSF103473 3 191 2.09E-39 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS05105 bdbd4617bec12be72b7804bb6d3ccbe7 420 TIGRFAM TIGR00896 CynX: cyanate transporter 7 392 4.2E-135 T 10-11-2016 IPR004747 Cyanate transport system protein GO:0016021 A4G23_RS05105 bdbd4617bec12be72b7804bb6d3ccbe7 420 Pfam PF07690 Major Facilitator Superfamily 25 370 2.2E-20 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS05105 bdbd4617bec12be72b7804bb6d3ccbe7 420 Gene3D G3DSA:1.20.1250.20 7 193 1.1E-18 T 10-11-2016 A4G23_RS06720 db72f50444e19f4a62de9e61f7598a4d 172 Pfam PF14024 Protein of unknown function (DUF4240) 1 127 1.1E-41 T 10-11-2016 IPR025334 Domain of unknown function (DUF4240 A4G23_RS21720 121c5ba3154fe44cecc1c2621d215809 137 Pfam PF13586 Transposase DDE domain 41 136 3.3E-17 T 10-11-2016 IPR025668 Transposase DDE domain A4G23_RS11755 83a7671d5eacc98dd90fba8cf71a9adf 89 Pfam PF13223 Protein of unknown function (DUF4031) 4 77 5.8E-30 T 10-11-2016 IPR025109 Domain of unknown function DUF4031 A4G23_RS05885 1d9a73c0d24c30a6b68da175762ca431 456 Pfam PF02653 Branched-chain amino acid transport system / permease component 145 418 1.0E-46 T 10-11-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 A4G23_RS13815 f3ee9f9cbf51f8688f0e816ed1f44023 246 Pfam PF07987 Domain of unkown function (DUF1775) 31 179 3.6E-51 T 10-11-2016 IPR012533 GLE1, N-terminal, bacteria A4G23_RS14870 d740bc803b458fbb5b37d0ec6668ab91 164 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 20 138 2.0E-23 T 10-11-2016 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III A4G23_RS22680 6221671dcb73ea85311aa838c05352a5 180 Gene3D G3DSA:3.40.630.30 2 175 1.2E-34 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS22680 6221671dcb73ea85311aa838c05352a5 180 Pfam PF13302 Acetyltransferase (GNAT) domain 9 145 3.9E-16 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS22680 6221671dcb73ea85311aa838c05352a5 180 SUPERFAMILY SSF55729 2 170 2.88E-33 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS01915 7d1b4ae30714b95ee1b0ad367a8913ca 470 Pfam PF10009 Uncharacterized protein conserved in bacteria (DUF2252) 56 457 7.2E-141 T 10-11-2016 IPR018721 Protein of unknown function DUF2252 A4G23_RS18260 48180e9fc1a7792c2071223468c6c756 122 Pfam PF02467 Transcription factor WhiB 29 97 8.7E-22 T 10-11-2016 IPR003482 Transcription factor WhiB A4G23_RS18260 48180e9fc1a7792c2071223468c6c756 122 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 19 105 18.542 T 10-11-2016 IPR003482 Transcription factor WhiB A4G23_RS07235 72b0584cef194a9a236883b9337e196c 194 Pfam PF01169 Uncharacterized protein family UPF0016 111 183 6.1E-19 T 10-11-2016 IPR001727 Gdt1 family GO:0032472 A4G23_RS07235 72b0584cef194a9a236883b9337e196c 194 Pfam PF01169 Uncharacterized protein family UPF0016 10 79 3.8E-15 T 10-11-2016 IPR001727 Gdt1 family GO:0032472 A4G23_RS19290 d8a1b3e784d7c34e6dea0df00fa95330 136 Pfam PF05331 Protein of unknown function (DUF742) 15 136 1.8E-38 T 10-11-2016 IPR007995 Protein of unknown function DUF742 A4G23_RS07490 425a79c666df6d82645117c24d7bcc6d 394 Pfam PF13556 PucR C-terminal helix-turn-helix domain 326 383 8.7E-20 T 10-11-2016 IPR025736 PucR C-terminal helix-turn-helix domain A4G23_RS11060 f39e46fc983e7e36bba2a6e3536a9c0e 84 SUPERFAMILY SSF143120 7 45 9.02E-5 T 10-11-2016 A4G23_RS13630 95b3c258cdcdc90c242102f55d7156d3 456 SUPERFAMILY SSF56601 24 337 1.0E-73 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS13630 95b3c258cdcdc90c242102f55d7156d3 456 Gene3D G3DSA:3.40.710.10 26 336 5.4E-76 T 10-11-2016 IPR012338 Beta-lactamase/transpeptidase-like A4G23_RS13630 95b3c258cdcdc90c242102f55d7156d3 456 Pfam PF00144 Beta-lactamase 25 334 1.8E-60 T 10-11-2016 IPR001466 Beta-lactamase-related A4G23_RS27020 de38b3585faf642b340b161e3d0ee1ea 186 Gene3D G3DSA:3.40.630.30 14 181 1.2E-39 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS27020 de38b3585faf642b340b161e3d0ee1ea 186 SUPERFAMILY SSF55729 6 175 3.04E-35 T 10-11-2016 IPR016181 Acyl-CoA N-acyltransferase A4G23_RS27020 de38b3585faf642b340b161e3d0ee1ea 186 Pfam PF13302 Acetyltransferase (GNAT) domain 15 151 2.1E-17 T 10-11-2016 IPR000182 GNAT domain GO:0008080 A4G23_RS00505 688186257712ea9db24375ae1f4739ce 104 Pfam PF00741 Gas vesicle protein 19 57 3.0E-17 T 10-11-2016 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 A4G23_RS00505 688186257712ea9db24375ae1f4739ce 104 ProSitePatterns PS00234 Gas vesicles protein GVPa signature 1. 20 34 - T 10-11-2016 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 A4G23_RS07540 a49e5315362f67a5eddf989cc43600b0 278 Pfam PF07264 Etoposide-induced protein 2.4 (EI24) 12 229 3.2E-33 T 10-11-2016 A4G23_RS20815 1a19db37d59743f66d0571cc2eefe128 527 Pfam PF07905 Purine catabolism regulatory protein-like family 8 126 2.9E-33 T 10-11-2016 IPR012914 Purine catabolism PurC-like domain A4G23_RS20815 1a19db37d59743f66d0571cc2eefe128 527 Pfam PF13556 PucR C-terminal helix-turn-helix domain 454 511 1.6E-22 T 10-11-2016 IPR025736 PucR C-terminal helix-turn-helix domain A4G23_RS10765 94bb71f3eb41a003c4e1097f5bcfe13e 246 Gene3D G3DSA:1.10.260.40 3 52 7.9E-5 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS24235 9f195f465ff990676f8fb65a7949e6eb 66 Pfam PF09957 Bacterial antitoxin of type II TA system, VapB 3 44 2.2E-7 T 10-11-2016 IPR019239 Bacterial antitoxin of type II TA system, VapB A4G23_RS20810 62c69ff4dc6e330409dbf77dad2f76a9 739 SUPERFAMILY SSF52540 328 659 1.99E-5 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS06880 9fc483a82f07a72ae2d2e8440413cdbd 260 Pfam PF14378 PAP2 superfamily 65 243 1.9E-48 T 10-11-2016 IPR026841 Inositolphosphotransferase Aur1/Ipt1 A4G23_RS07365 7834058a0788789582ff8f926d687abc 71 Pfam PF09723 Zinc ribbon domain 1 40 3.9E-12 T 10-11-2016 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain A4G23_RS07365 7834058a0788789582ff8f926d687abc 71 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 46 1.4E-16 T 10-11-2016 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain A4G23_RS07365 7834058a0788789582ff8f926d687abc 71 SMART SM00834 1 42 2.9E-13 T 10-11-2016 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain A4G23_RS18270 07be52ef8e0df8761bee423dcc9352bd 174 Pfam PF14030 Protein of unknown function (DUF4245) 5 169 6.6E-48 T 10-11-2016 IPR025339 Protein of unknown function DUF4245 A4G23_RS06370 bfdd1bc1daf991b0a3e1b4bff90ea57d 264 SUPERFAMILY SSF110399 4 242 1.26E-84 T 10-11-2016 IPR008867 Thiazole biosynthesis GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 A4G23_RS06370 bfdd1bc1daf991b0a3e1b4bff90ea57d 264 Gene3D G3DSA:3.20.20.70 6 255 2.9E-62 T 10-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 A4G23_RS06370 bfdd1bc1daf991b0a3e1b4bff90ea57d 264 Pfam PF05690 Thiazole biosynthesis protein ThiG 8 250 7.5E-110 T 10-11-2016 A4G23_RS06370 bfdd1bc1daf991b0a3e1b4bff90ea57d 264 Hamap MF_00443 Thiazole synthase [thiG]. 5 256 43.686 T 10-11-2016 IPR008867 Thiazole biosynthesis GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 A4G23_RS14070 9cd1383a62264f331a4827a54b632cf8 120 Pfam PF04686 Streptomyces sporulation and cell division protein, SsgA 18 105 7.1E-26 T 10-11-2016 IPR006776 Sporulation-specific cell division protein SsgB GO:0051301 A4G23_RS15495 9391e9c6636e43d0aa4f01cda48bbcc2 261 ProDom PD040376 SCO3349 RV0495C/MT0515 ML2435 MB0506C CGL0407 11 255 6.0E-122 T 10-11-2016 A4G23_RS05210 9ce2c14e0d20aa70f6f19ea06ff1f9d1 314 Pfam PF04116 Fatty acid hydroxylase superfamily 87 219 1.8E-28 T 10-11-2016 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0006633|GO:0016491|GO:0055114 A4G23_RS14820 02f4688ac405e75b3d79a06427634aa8 157 Pfam PF14588 YjgF/chorismate_mutase-like, putative endoribonuclease 7 153 5.0E-35 T 10-11-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like A4G23_RS14820 02f4688ac405e75b3d79a06427634aa8 157 SUPERFAMILY SSF55298 5 153 4.24E-55 T 10-11-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like A4G23_RS14820 02f4688ac405e75b3d79a06427634aa8 157 Gene3D G3DSA:3.30.1330.40 4 153 1.2E-66 T 10-11-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like A4G23_RS15580 9bc21a27c168659fe8f248b1b623452e 271 Pfam PF15698 Phosphatase 7 269 6.8E-116 T 10-11-2016 IPR031423 Uncharacterised phosphatase SCO2771 A4G23_RS14730 869622969d04093c8d10ff3c6990cd02 219 Pfam PF16702 Domain of unknown function (DUF5063) 13 172 3.0E-41 T 10-11-2016 IPR032025 Protein of unknown function DUF5063 A4G23_RS07460 df7070db3062b404facfdc821f40687e 343 Pfam PF06259 Alpha/beta hydrolase 124 292 2.1E-44 T 10-11-2016 IPR010427 Protein of unknown function DUF1023 A4G23_RS09220 d78d7a1ba5495d8a7f2ec54a41f13f15 200 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 27 152 2.7E-6 T 10-11-2016 IPR015330 DNA primase/polymerase, bifunctional, N-terminal A4G23_RS23790 80f6b40cea8b215d9b6f14d6badc33d3 212 Pfam PF16715 Cyclodipeptide synthase 1 200 1.9E-58 T 10-11-2016 IPR030903 Cyclodileucine synthase GO:0016755 A4G23_RS23790 80f6b40cea8b215d9b6f14d6badc33d3 212 TIGRFAM TIGR04539 tRNA_cyclodipep: tRNA-dependent cyclodipeptide synthase 1 200 8.3E-69 T 10-11-2016 IPR030903 Cyclodileucine synthase GO:0016755 A4G23_RS09345 5f6603b64fe2a409cf1cd37cc49bfa79 435 Pfam PF04286 Protein of unknown function (DUF445) 70 431 8.8E-101 T 10-11-2016 IPR007383 Protein of unknown function DUF445 A4G23_RS13040 4e0acccb9993fe2701a3761bdc4eb2f4 506 PIRSF PIRSF006060 1 472 2.8E-56 T 10-11-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A4G23_RS13040 4e0acccb9993fe2701a3761bdc4eb2f4 506 Pfam PF13520 Amino acid permease 16 392 1.5E-30 T 10-11-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A4G23_RS26040 dc039d30f20cace069ea599360321722 366 SUPERFAMILY SSF48576 10 338 4.03E-43 T 10-11-2016 IPR008949 Isoprenoid synthase domain A4G23_RS26040 dc039d30f20cace069ea599360321722 366 Gene3D G3DSA:1.10.600.10 6 338 8.8E-70 T 10-11-2016 IPR008949 Isoprenoid synthase domain A4G23_RS04030 18449603c48450ddfd8bdd6c72f66f5d 222 SUPERFAMILY SSF50475 46 166 7.59E-14 T 10-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 A4G23_RS04030 18449603c48450ddfd8bdd6c72f66f5d 222 Gene3D G3DSA:2.30.110.10 40 164 1.1E-24 T 10-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 A4G23_RS04030 18449603c48450ddfd8bdd6c72f66f5d 222 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 46 139 2.1E-13 T 10-11-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 A4G23_RS04030 18449603c48450ddfd8bdd6c72f66f5d 222 TIGRFAM TIGR04025 PPOX_FMN_DR2398: pyridoxamine 5'-phosphate oxidase, FMN-binding family 25 211 3.5E-61 T 10-11-2016 IPR024029 Pyridoxamine 5-phosphate oxidase, FMN-dependent A4G23_RS10285 2b8cc841d790804d8796eb27131848fd 479 SUPERFAMILY SSF140459 15 79 8.63E-5 T 10-11-2016 A4G23_RS01015 dc40ce4a02540802908e050d6ecf5a5e 414 Pfam PF06081 Aromatic acid exporter family member 1 22 158 4.4E-11 T 10-11-2016 IPR010343 Aromatic acid exporter family member 1 A4G23_RS12930 0956bc0781e6124d70880c9aef5124a7 264 PIRSF PIRSF006648 1 259 5.0E-17 T 10-11-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 A4G23_RS12930 0956bc0781e6124d70880c9aef5124a7 264 Pfam PF01061 ABC-2 type transporter 18 226 5.3E-17 T 10-11-2016 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A4G23_RS22670 d80ed5c5952f7f13a60badde09c099fb 307 Gene3D G3DSA:3.20.20.30 8 302 8.6E-76 T 10-11-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4G23_RS22670 d80ed5c5952f7f13a60badde09c099fb 307 TIGRFAM TIGR03560 F420_Rv1855c: probable F420-dependent oxidoreductase, Rv1855c family 2 228 6.2E-91 T 10-11-2016 IPR019952 F420-dependent oxidoreductase-predicted, Rv1855c A4G23_RS22670 d80ed5c5952f7f13a60badde09c099fb 307 Pfam PF00296 Luciferase-like monooxygenase 8 248 5.3E-54 T 10-11-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4G23_RS22670 d80ed5c5952f7f13a60badde09c099fb 307 SUPERFAMILY SSF51679 4 302 4.45E-69 T 10-11-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A4G23_RS04450 b9dbc431fc0de151b6fa3574692d2f47 235 Pfam PF03777 Small secreted domain (DUF320) 26 80 4.2E-25 T 10-11-2016 IPR005528 Domain of unknown function DUF320, Streptomyces species A4G23_RS04450 b9dbc431fc0de151b6fa3574692d2f47 235 Pfam PF03777 Small secreted domain (DUF320) 82 134 9.1E-24 T 10-11-2016 IPR005528 Domain of unknown function DUF320, Streptomyces species A4G23_RS18425 cc0acb7b8202ac19d87f58d4eaf96565 353 Pfam PF00005 ABC transporter 40 197 2.5E-29 T 10-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4G23_RS18425 cc0acb7b8202ac19d87f58d4eaf96565 353 SMART SM00382 48 247 6.5E-14 T 10-11-2016 IPR003593 AAA+ ATPase domain A4G23_RS18425 cc0acb7b8202ac19d87f58d4eaf96565 353 Gene3D G3DSA:3.40.50.300 19 271 1.1E-75 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS18425 cc0acb7b8202ac19d87f58d4eaf96565 353 ProSitePatterns PS00211 ABC transporters family signature. 170 184 - T 10-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4G23_RS18425 cc0acb7b8202ac19d87f58d4eaf96565 353 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 249 311 1.4E-18 T 10-11-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A4G23_RS18425 cc0acb7b8202ac19d87f58d4eaf96565 353 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 248 334 3.3E-21 T 10-11-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A4G23_RS18425 cc0acb7b8202ac19d87f58d4eaf96565 353 SUPERFAMILY SSF52540 20 268 5.79E-69 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS01900 159114c5a4fd7966fbb525eaa260e85d 152 Pfam PF13396 Phospholipase_D-nuclease N-terminal 27 73 9.8E-7 T 10-11-2016 IPR027379 Cardiolipin synthase N-terminal A4G23_RS01900 159114c5a4fd7966fbb525eaa260e85d 152 Pfam PF09851 Short C-terminal domain 110 136 6.4E-7 T 10-11-2016 IPR018649 SHOCT domain A4G23_RS21360 4b065fd5808257c59740b059f9327082 472 Pfam PF13830 Domain of unknown function (DUF4192) 19 362 3.8E-99 T 10-11-2016 IPR025447 Protein of unknown function DUF4192 A4G23_RS05570 cc178477610cd6bbb7387ae341bd599d 105 SUPERFAMILY SSF50022 1 103 3.4E-31 T 10-11-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A4G23_RS05570 cc178477610cd6bbb7387ae341bd599d 105 Gene3D G3DSA:2.102.10.10 1 103 1.3E-33 T 10-11-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A4G23_RS05570 cc178477610cd6bbb7387ae341bd599d 105 Pfam PF00355 Rieske [2Fe-2S] domain 4 89 1.0E-19 T 10-11-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A4G23_RS01585 0ff69a8d8ec5336440ff8a5807076e67 706 SUPERFAMILY SSF49899 476 702 3.45E-19 T 10-11-2016 IPR013320 Concanavalin A-like lectin/glucanase domain A4G23_RS01585 0ff69a8d8ec5336440ff8a5807076e67 706 SUPERFAMILY SSF49899 276 468 2.74E-25 T 10-11-2016 IPR013320 Concanavalin A-like lectin/glucanase domain A4G23_RS01585 0ff69a8d8ec5336440ff8a5807076e67 706 Gene3D G3DSA:2.60.120.200 530 701 4.3E-20 T 10-11-2016 IPR013320 Concanavalin A-like lectin/glucanase domain A4G23_RS01585 0ff69a8d8ec5336440ff8a5807076e67 706 Gene3D G3DSA:2.60.120.200 307 467 1.4E-25 T 10-11-2016 IPR013320 Concanavalin A-like lectin/glucanase domain A4G23_RS01585 0ff69a8d8ec5336440ff8a5807076e67 706 SMART SM00560 329 461 3.2E-15 T 10-11-2016 IPR006558 LamG-like jellyroll fold A4G23_RS01585 0ff69a8d8ec5336440ff8a5807076e67 706 SMART SM00560 553 696 1.8E-5 T 10-11-2016 IPR006558 LamG-like jellyroll fold A4G23_RS01585 0ff69a8d8ec5336440ff8a5807076e67 706 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 536 699 3.6E-17 T 10-11-2016 A4G23_RS01585 0ff69a8d8ec5336440ff8a5807076e67 706 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 320 462 2.2E-24 T 10-11-2016 A4G23_RS01205 ffa3a42b64009d24267ef8bd99ca4c27 68 Pfam PF11387 Protein of unknown function (DUF2795) 23 57 7.6E-5 T 10-11-2016 IPR021527 Protein of unknown function DUF2795 A4G23_RS22425 52fdcdadd7323e00167e747b890060ee 133 SUPERFAMILY SSF88723 9 123 4.71E-8 T 10-11-2016 IPR029060 PIN domain-like A4G23_RS11865 4eee0ee7a0869c9e191324677f6f55bf 306 Pfam PF11228 Protein of unknown function (DUF3027) 41 259 6.7E-84 T 10-11-2016 IPR021391 Protein of unknown function DUF3027 A4G23_RS25195 bd9521c3ffdfadcd1aa03afcdf1049ad 315 Pfam PF01435 Peptidase family M48 75 292 1.3E-35 T 10-11-2016 IPR001915 Peptidase M48 GO:0004222|GO:0006508 A4G23_RS25195 bd9521c3ffdfadcd1aa03afcdf1049ad 315 Gene3D G3DSA:3.30.2010.10 67 156 1.5E-30 T 10-11-2016 A4G23_RS25195 bd9521c3ffdfadcd1aa03afcdf1049ad 315 Hamap MF_00188 Protease HtpX [htpX]. 7 293 25.843 T 10-11-2016 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 A4G23_RS07395 ac3fd9d985b21031ad1658a85f0f7d35 383 Pfam PF04332 Protein of unknown function (DUF475) 44 360 3.3E-132 T 10-11-2016 IPR007427 Protein of unknown function DUF475 A4G23_RS26180 5548288112dde8e07752db6d15aed89d 459 SUPERFAMILY SSF49785 333 445 3.74E-15 T 10-11-2016 IPR008979 Galactose-binding domain-like A4G23_RS26180 5548288112dde8e07752db6d15aed89d 459 SUPERFAMILY SSF75005 42 329 3.0E-60 T 10-11-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain A4G23_RS26180 5548288112dde8e07752db6d15aed89d 459 Gene3D G3DSA:2.60.120.260 335 458 1.1E-15 T 10-11-2016 IPR008979 Galactose-binding domain-like A4G23_RS26180 5548288112dde8e07752db6d15aed89d 459 Pfam PF04616 Glycosyl hydrolases family 43 46 308 2.8E-39 T 10-11-2016 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 A4G23_RS26180 5548288112dde8e07752db6d15aed89d 459 Gene3D G3DSA:2.115.10.20 46 333 1.3E-62 T 10-11-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain A4G23_RS06745 eec4bfaab59c349abaf71e4fd069c9b6 583 Gene3D G3DSA:1.25.40.10 350 379 4.0E-5 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS06745 eec4bfaab59c349abaf71e4fd069c9b6 583 Gene3D G3DSA:1.25.40.10 475 541 4.0E-5 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS25210 31135687f2ed5c2cd661ed62f8622d11 251 Pfam PF10014 2OG-Fe dioxygenase 55 247 2.9E-57 T 10-11-2016 IPR018724 2OG-Fe dioxygenase A4G23_RS09520 a7ae3e664e0b5a0b910096fa2aa3b1e8 139 Pfam PF04686 Streptomyces sporulation and cell division protein, SsgA 24 121 3.9E-34 T 10-11-2016 IPR006776 Sporulation-specific cell division protein SsgB GO:0051301 A4G23_RS09430 d901064ef5937c27513ae1e4ba934c96 428 Pfam PF02378 Phosphotransferase system, EIIC 34 346 1.9E-63 T 10-11-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 A4G23_RS23645 2089be0f685265d5c54526cc73d2ce42 69 SUPERFAMILY SSF57716 34 67 2.57E-6 T 10-11-2016 A4G23_RS23645 2089be0f685265d5c54526cc73d2ce42 69 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 37 61 - T 10-11-2016 IPR020458 Zinc finger, DksA/TraR C4-type conserved site A4G23_RS00725 9a6d46667a49e0c563d165fdee8b50d9 230 Gene3D G3DSA:1.10.260.40 6 37 2.7E-4 T 10-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A4G23_RS21140 9e15f6385c99ee464498090f4e9622bb 308 SUPERFAMILY SSF48239 253 305 6.28E-8 T 10-11-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A4G23_RS21140 9e15f6385c99ee464498090f4e9622bb 308 SUPERFAMILY SSF48239 50 152 6.28E-8 T 10-11-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A4G23_RS21140 9e15f6385c99ee464498090f4e9622bb 308 Gene3D G3DSA:1.50.10.20 267 276 4.6E-4 T 10-11-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A4G23_RS21140 9e15f6385c99ee464498090f4e9622bb 308 Gene3D G3DSA:1.50.10.20 50 101 4.6E-4 T 10-11-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A4G23_RS10650 f7245e40eae4c715678b6d5bea274348 493 Pfam PF01757 Acyltransferase family 24 352 2.6E-19 T 10-11-2016 IPR002656 Acyltransferase 3 GO:0016747 A4G23_RS16045 fbbc11cdd55dde4cc50d4fedada48e98 119 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 19 118 2.0E-36 T 10-11-2016 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS16045 fbbc11cdd55dde4cc50d4fedada48e98 119 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 1 119 17.927 T 10-11-2016 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 A4G23_RS07385 05d8b8d43f9ac1a9865d6c3a6733c4b6 363 Pfam PF02342 TerD domain 1 175 2.7E-42 T 10-11-2016 IPR003325 TerD domain GO:0006950 A4G23_RS07385 05d8b8d43f9ac1a9865d6c3a6733c4b6 363 Gene3D G3DSA:2.60.60.30 17 171 4.7E-27 T 10-11-2016 A4G23_RS18155 af1adbdbb3919cd12fcb7a9c660114b7 126 Pfam PF02643 Uncharacterized ACR, COG1430 20 113 1.7E-16 T 10-11-2016 IPR003795 Protein of unknown function DUF192 A4G23_RS15295 c09b9e70fc31e4e63bade7ca80648981 154 SUPERFAMILY SSF54427 6 139 9.79E-41 T 10-11-2016 IPR032710 NTF2-like domain A4G23_RS15295 c09b9e70fc31e4e63bade7ca80648981 154 Gene3D G3DSA:3.10.450.50 4 149 2.3E-53 T 10-11-2016 IPR032710 NTF2-like domain A4G23_RS15295 c09b9e70fc31e4e63bade7ca80648981 154 Pfam PF13474 SnoaL-like domain 11 139 2.8E-32 T 10-11-2016 IPR009959 Polyketide cyclase SnoaL-like domain A4G23_RS10435 99cf8097f8be55e0adc9882c69b44956 273 Pfam PF00837 Iodothyronine deiodinase 59 122 1.2E-7 T 10-11-2016 IPR000643 Iodothyronine deiodinase GO:0004800|GO:0055114 Reactome: R-HSA-350864 A4G23_RS10435 99cf8097f8be55e0adc9882c69b44956 273 Gene3D G3DSA:3.40.30.10 38 189 2.1E-15 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS10435 99cf8097f8be55e0adc9882c69b44956 273 SUPERFAMILY SSF52833 36 192 6.18E-17 T 10-11-2016 IPR012336 Thioredoxin-like fold A4G23_RS26070 6deef2c1e3d389b7b1d4eb68cdf4b3f3 122 Pfam PF05331 Protein of unknown function (DUF742) 8 119 3.7E-17 T 10-11-2016 IPR007995 Protein of unknown function DUF742 A4G23_RS26070 6deef2c1e3d389b7b1d4eb68cdf4b3f3 122 Gene3D G3DSA:1.10.10.10 51 99 1.3E-4 T 10-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain A4G23_RS20680 17718b47b14f01ccc50d57210c17947e 230 Pfam PF13828 Domain of unknown function (DUF4190) 125 191 2.3E-11 T 10-11-2016 IPR025241 Domain of unknown function DUF4190 A4G23_RS08015 601554c2b51b45405d8c09833ef9c19b 513 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 217 393 7.5E-12 T 10-11-2016 IPR004477 ComEC/Rec2-related protein A4G23_RS08015 601554c2b51b45405d8c09833ef9c19b 513 Pfam PF03772 Competence protein 195 471 2.8E-40 T 10-11-2016 IPR004477 ComEC/Rec2-related protein A4G23_RS16090 ea46f1e2a96be39f0869be2abd134cbe 275 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 30 175 3.5E-31 T 10-11-2016 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4G23_RS00210 dfaf7cba52a21ee3908d067064fad12e 93 Pfam PF02583 Metal-sensitive transcriptional repressor 11 82 5.1E-26 T 10-11-2016 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 A4G23_RS17055 9d1822c9bc24a28e5f14dcd318d58d4c 315 Pfam PF14433 SUKH-3 immunity protein 8 145 9.8E-25 T 10-11-2016 IPR025850 SUKH-3 immunity protein A4G23_RS17185 4300300fa89ac9363168fb75d0925d63 197 Pfam PF14124 Domain of unknown function (DUF4291) 8 185 4.5E-71 T 10-11-2016 IPR025633 Protein of unknown function DUF4291 A4G23_RS12005 1652c08c7e5ed14f5d3e33739848cce6 162 Gene3D G3DSA:3.90.550.10 35 159 1.7E-9 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS12005 1652c08c7e5ed14f5d3e33739848cce6 162 SUPERFAMILY SSF53448 35 162 2.04E-32 T 10-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases A4G23_RS12005 1652c08c7e5ed14f5d3e33739848cce6 162 Pfam PF00535 Glycosyl transferase family 2 36 155 1.5E-9 T 10-11-2016 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A4G23_RS02360 a21377deda9914550650477aaf95f4b6 714 SUPERFAMILY SSF53756 126 204 1.2E-25 T 10-11-2016 A4G23_RS02360 a21377deda9914550650477aaf95f4b6 714 SUPERFAMILY SSF53756 19 75 1.2E-25 T 10-11-2016 A4G23_RS02360 a21377deda9914550650477aaf95f4b6 714 SUPERFAMILY SSF53756 242 538 1.2E-25 T 10-11-2016 A4G23_RS02360 a21377deda9914550650477aaf95f4b6 714 Pfam PF08323 Starch synthase catalytic domain 6 159 4.1E-6 T 10-11-2016 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 A4G23_RS02360 a21377deda9914550650477aaf95f4b6 714 Gene3D G3DSA:3.40.50.2000 319 517 7.8E-17 T 10-11-2016 A4G23_RS11910 1a42dfbc25709706f4ac8ad5361997f4 482 Pfam PF00860 Permease family 40 438 4.3E-27 T 10-11-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 A4G23_RS00580 a5be7da807e5ec3594986aa467575fdb 496 SUPERFAMILY SSF48452 240 450 3.8E-5 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS00580 a5be7da807e5ec3594986aa467575fdb 496 Gene3D G3DSA:1.25.40.10 242 350 7.5E-4 T 10-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A4G23_RS00910 173eb09c635570444e1297411b72d738 537 Pfam PF07690 Major Facilitator Superfamily 33 425 1.8E-48 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS00910 173eb09c635570444e1297411b72d738 537 Gene3D G3DSA:1.20.1250.20 27 209 4.5E-30 T 10-11-2016 A4G23_RS00910 173eb09c635570444e1297411b72d738 537 Gene3D G3DSA:1.20.1250.20 273 436 2.8E-21 T 10-11-2016 A4G23_RS00910 173eb09c635570444e1297411b72d738 537 Gene3D G3DSA:1.20.1250.20 488 514 2.8E-21 T 10-11-2016 A4G23_RS00910 173eb09c635570444e1297411b72d738 537 SUPERFAMILY SSF103473 11 211 4.58E-62 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS00910 173eb09c635570444e1297411b72d738 537 SUPERFAMILY SSF103473 487 514 4.58E-62 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS00910 173eb09c635570444e1297411b72d738 537 SUPERFAMILY SSF103473 263 435 4.58E-62 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS03480 21eea5edd9209108b0abd0ba3d230a96 337 SUPERFAMILY SSF100950 74 319 8.84E-56 T 10-11-2016 A4G23_RS03480 21eea5edd9209108b0abd0ba3d230a96 337 Gene3D G3DSA:3.40.50.1360 63 319 5.3E-69 T 10-11-2016 A4G23_RS03480 21eea5edd9209108b0abd0ba3d230a96 337 Pfam PF04198 Putative sugar-binding domain 70 319 1.3E-66 T 10-11-2016 IPR007324 Sugar-binding domain, putative GO:0030246 A4G23_RS24705 4fe78b247131b7b3799abbc1ee675e1b 324 Gene3D G3DSA:1.10.620.20 8 313 6.9E-109 T 10-11-2016 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: R-HSA-499943 A4G23_RS24705 4fe78b247131b7b3799abbc1ee675e1b 324 Pfam PF03405 Fatty acid desaturase 18 317 6.1E-76 T 10-11-2016 IPR005067 Fatty acid desaturase, type 2 GO:0006631|GO:0045300|GO:0055114 A4G23_RS24705 4fe78b247131b7b3799abbc1ee675e1b 324 PIRSF PIRSF000346 1 323 5.6E-115 T 10-11-2016 IPR005067 Fatty acid desaturase, type 2 GO:0006631|GO:0045300|GO:0055114 A4G23_RS24705 4fe78b247131b7b3799abbc1ee675e1b 324 SUPERFAMILY SSF47240 5 319 5.88E-83 T 10-11-2016 IPR009078 Ferritin-like superfamily A4G23_RS10015 d3857b80ce75326fa6f5f35f1e2fb5c0 263 SUPERFAMILY SSF56801 6 258 8.77E-20 T 10-11-2016 A4G23_RS10015 d3857b80ce75326fa6f5f35f1e2fb5c0 263 Gene3D G3DSA:3.40.50.980 186 258 1.2E-5 T 10-11-2016 A4G23_RS10015 d3857b80ce75326fa6f5f35f1e2fb5c0 263 TIGRFAM TIGR03089 TIGR03089: TIGR03089 family protein 11 257 7.0E-78 T 10-11-2016 IPR017523 Conserved hypothetical protein CHP03089 A4G23_RS10015 d3857b80ce75326fa6f5f35f1e2fb5c0 263 Gene3D G3DSA:3.40.50.980 7 90 2.3E-6 T 10-11-2016 A4G23_RS04760 3b7f97dbd8c3bc2edfabdbfe1a609345 144 Hamap MF_01197 Cell division protein SepF [sepF]. 1 135 19.13 T 10-11-2016 IPR023052 Cell division protein SepF GO:0090529 A4G23_RS04760 3b7f97dbd8c3bc2edfabdbfe1a609345 144 Pfam PF04472 Protein of unknown function (DUF552) 56 124 7.6E-24 T 10-11-2016 IPR007561 Cell division protein SepF/SepF-related GO:0090529 A4G23_RS15915 88ecaed263bcfc44a323067b378a44e7 82 Pfam PF14012 Protein of unknown function (DUF4229) 1 65 1.0E-18 T 10-11-2016 IPR025323 Protein of unknown function DUF4229 A4G23_RS26225 22443f0f77aaf6c742ae54bf13c44bf7 506 Pfam PF03659 Glycosyl hydrolase family 71 130 472 3.4E-31 T 10-11-2016 IPR005197 Glycoside hydrolase family 71 GO:0016787 A4G23_RS07190 e2b34c1c527ee6a2f1db82c3fe2fd094 360 Pfam PF02361 Cobalt transport protein 10 226 3.2E-5 T 10-11-2016 IPR003339 ABC/ECF transporter, transmembrane component A4G23_RS15055 e76acfd75074847c0d9fadd05ea836ad 79 Pfam PF03777 Small secreted domain (DUF320) 23 78 1.1E-28 T 10-11-2016 IPR005528 Domain of unknown function DUF320, Streptomyces species A4G23_RS18915 db8313da18c8b6eb23b3d94a06fc6f8c 234 Pfam PF13398 Peptidase M50B-like 24 225 1.1E-64 T 10-11-2016 A4G23_RS09475 ccdeeda69aa1a1ebc2e0c800a0e1137c 194 Pfam PF09438 Domain of unknown function (DUF2017) 9 193 8.6E-62 T 10-11-2016 IPR018561 Domain of unknown function DUF2017 A4G23_RS02410 ac230b0d11c100cd7e9b2fab6996c050 263 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 256 1.7E-36 T 10-11-2016 IPR007404 LexA-binding, inner membrane-associated putative hydrolase A4G23_RS02790 190b9adc14cdf1799bdcf78349b6c721 291 Gene3D G3DSA:3.40.50.1820 18 288 9.1E-26 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS02790 190b9adc14cdf1799bdcf78349b6c721 291 SUPERFAMILY SSF53474 18 288 8.19E-24 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS05155 48c7541ca3d9b187a7784ccbc2c07658 463 Pfam PF01523 Putative modulator of DNA gyrase 24 325 3.7E-31 T 10-11-2016 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 A4G23_RS05155 48c7541ca3d9b187a7784ccbc2c07658 463 SUPERFAMILY SSF111283 9 456 2.22E-67 T 10-11-2016 A4G23_RS02150 11cf6536f43e3406614645bf77a987d7 404 Pfam PF13556 PucR C-terminal helix-turn-helix domain 334 392 3.0E-20 T 10-11-2016 IPR025736 PucR C-terminal helix-turn-helix domain A4G23_RS26090 15d23213a1862e4cf6dbb8197f40f9c9 149 Pfam PF14325 Domain of unknown function (DUF4383) 16 139 1.8E-42 T 10-11-2016 IPR025492 Protein of unknown function DUF4383 A4G23_RS04860 5ca58bb4434b3b2c6d71f87db138af99 276 Pfam PF10127 Predicted nucleotidyltransferase 17 225 2.7E-38 T 10-11-2016 IPR018775 Nucleotidyltransferase, predicted A4G23_RS21875 0e041d2d118c071f4f516831b239715a 118 Pfam PF05331 Protein of unknown function (DUF742) 10 118 1.1E-38 T 10-11-2016 IPR007995 Protein of unknown function DUF742 A4G23_RS17590 62c053e11d0643056ad8cb24d0e671bf 369 Pfam PF02653 Branched-chain amino acid transport system / permease component 57 334 1.0E-40 T 10-11-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 A4G23_RS23605 17199477ce5a68d47934276cc8bc9c23 139 SUPERFAMILY SSF55874 49 138 6.3E-8 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS23605 17199477ce5a68d47934276cc8bc9c23 139 Pfam PF13581 Histidine kinase-like ATPase domain 36 134 1.7E-8 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS23230 64f1e1a9244f5fdb3ac4aee8273ccd64 128 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 119 3.7E-9 T 10-11-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4G23_RS23230 64f1e1a9244f5fdb3ac4aee8273ccd64 128 SUPERFAMILY SSF54593 4 125 4.83E-21 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS23230 64f1e1a9244f5fdb3ac4aee8273ccd64 128 Gene3D G3DSA:3.10.180.10 3 126 6.7E-28 T 10-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4G23_RS22025 94c2ded788ab8a9bda4395bff8766e83 681 SUPERFAMILY SSF117892 56 176 6.41E-10 T 10-11-2016 IPR001107 Band 7 domain A4G23_RS15830 3b01f7d1700f0bb109c604e824545480 434 Gene3D G3DSA:3.20.20.370 98 407 1.0E-14 T 10-11-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 A4G23_RS15830 3b01f7d1700f0bb109c604e824545480 434 SUPERFAMILY SSF88713 177 407 3.06E-28 T 10-11-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A4G23_RS15830 3b01f7d1700f0bb109c604e824545480 434 SUPERFAMILY SSF88713 98 147 3.06E-28 T 10-11-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A4G23_RS08370 9625e788d7c1efaca50ad05cfba94aec 196 PIRSF PIRSF016661 12 195 2.1E-41 T 10-11-2016 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 A4G23_RS08370 9625e788d7c1efaca50ad05cfba94aec 196 Pfam PF02632 BioY family 51 190 3.6E-34 T 10-11-2016 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 A4G23_RS23660 04aa375bc8799428a7712a832792ed0f 221 Pfam PF09335 SNARE associated Golgi protein 45 172 1.4E-21 T 10-11-2016 IPR032816 SNARE associated Golgi protein A4G23_RS16475 49e5b4a9986c6c06f8f3951b0720a599 73 Pfam PF02467 Transcription factor WhiB 6 61 3.8E-9 T 10-11-2016 IPR003482 Transcription factor WhiB A4G23_RS07380 db32c632efdf124e6a31fa53b38077cd 395 Gene3D G3DSA:3.20.20.60 36 321 1.7E-39 T 10-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A4G23_RS07380 db32c632efdf124e6a31fa53b38077cd 395 Pfam PF15617 C-C_Bond_Lyase of the TIM-Barrel fold 32 377 1.3E-125 T 10-11-2016 A4G23_RS07380 db32c632efdf124e6a31fa53b38077cd 395 SUPERFAMILY SSF51621 288 321 5.18E-25 T 10-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A4G23_RS07380 db32c632efdf124e6a31fa53b38077cd 395 SUPERFAMILY SSF51621 35 257 5.18E-25 T 10-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A4G23_RS00390 2ce1883ec6ff25da31fc67693c614049 213 Pfam PF06736 Protein of unknown function (DUF1211) 24 112 4.9E-22 T 10-11-2016 IPR010617 Endosomal/lysomomal potassium channel TMEM175 GO:0005267 A4G23_RS03370 53eb1a16355ea52fd2da97129abb17b7 216 Pfam PF04973 Nicotinamide mononucleotide transporter 21 201 4.8E-39 T 10-11-2016 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 A4G23_RS13390 4776bf0e16d8731982675a6c40c334ad 228 ProDom PD190647 REGULATORY RESISTANCE TRANSCRIPTION TRANSCRIPTIONAL ANTIBIOTIC DNA-BINDING ACTIVATOR REGULATION ORF699 NOSIHEPTIDE 1 200 2.0E-37 T 10-11-2016 A4G23_RS20140 3265d899ac72b7a07e19fa8fd0e35c70 541 Gene3D G3DSA:1.10.10.60 472 509 6.7E-6 T 10-11-2016 IPR009057 Homeodomain-like GO:0003677 A4G23_RS20140 3265d899ac72b7a07e19fa8fd0e35c70 541 Pfam PF13556 PucR C-terminal helix-turn-helix domain 474 532 1.6E-21 T 10-11-2016 IPR025736 PucR C-terminal helix-turn-helix domain A4G23_RS09830 13e12ab2d18a3cfd661c7153738e7d32 388 Pfam PF06224 Winged helix DNA-binding domain 41 363 2.2E-67 T 10-11-2016 IPR009351 Protein of unknown function DUF1006 A4G23_RS20845 806a37b9404ae8d78f35d8b6078b99f9 377 Pfam PF04551 GcpE protein 15 354 3.0E-135 T 10-11-2016 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 A4G23_RS20845 806a37b9404ae8d78f35d8b6078b99f9 377 SUPERFAMILY SSF51717 38 212 1.02E-8 T 10-11-2016 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4G23_RS20845 806a37b9404ae8d78f35d8b6078b99f9 377 PIRSF PIRSF004640 4 366 2.5E-146 T 10-11-2016 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 A4G23_RS20845 806a37b9404ae8d78f35d8b6078b99f9 377 SUPERFAMILY SSF56014 268 353 2.05E-11 T 10-11-2016 A4G23_RS20845 806a37b9404ae8d78f35d8b6078b99f9 377 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 9 360 33.794 T 10-11-2016 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 A4G23_RS20845 806a37b9404ae8d78f35d8b6078b99f9 377 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 11 353 2.7E-129 T 10-11-2016 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 A4G23_RS21090 902d2ab3d715dbc8c5e8d880b2ecce79 299 Pfam PF01066 CDP-alcohol phosphatidyltransferase 33 103 7.3E-16 T 10-11-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A4G23_RS21090 902d2ab3d715dbc8c5e8d880b2ecce79 299 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 81 103 - T 10-11-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A4G23_RS21090 902d2ab3d715dbc8c5e8d880b2ecce79 299 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 33 202 6.3E-37 T 10-11-2016 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668 A4G23_RS19200 2fd40f015c61a0e94be6c25dd89ccc3b 297 Pfam PF13349 Putative adhesin 142 270 3.4E-10 T 10-11-2016 IPR025164 Putative adhesin A4G23_RS07320 d0139ddea714c0dc4408a7dd60ee0a87 312 SUPERFAMILY SSF55846 18 157 9.03E-12 T 10-11-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 A4G23_RS07320 d0139ddea714c0dc4408a7dd60ee0a87 312 Gene3D G3DSA:3.40.80.10 24 164 1.2E-7 T 10-11-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 A4G23_RS07320 d0139ddea714c0dc4408a7dd60ee0a87 312 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 24 155 2.0E-4 T 10-11-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 A4G23_RS21830 af68147b8d7db05487b58a6dafbcdce1 60 Pfam PF04149 Domain of unknown function (DUF397) 9 59 5.1E-21 T 10-11-2016 IPR007278 Domain of unknown function DUF397 A4G23_RS23210 b75324eb480b207ee92697bd1436bb55 449 Pfam PF01590 GAF domain 116 222 5.2E-8 T 10-11-2016 IPR003018 GAF domain GO:0005515 A4G23_RS22710 cb533a8ea0c066f14107cef2b1c763be 266 SUPERFAMILY SSF55073 6 139 1.13E-7 T 10-11-2016 IPR029787 Nucleotide cyclase A4G23_RS18990 b36477064b126c7e8abeca215a9d4f67 540 Pfam PF00474 Sodium:solute symporter family 44 407 2.4E-19 T 10-11-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 A4G23_RS10195 7adbb3d10bf19db674572e66df0470b5 462 Pfam PF02397 Bacterial sugar transferase 269 456 6.9E-56 T 10-11-2016 IPR003362 Bacterial sugar transferase A4G23_RS10195 7adbb3d10bf19db674572e66df0470b5 462 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 15 462 3.1E-112 T 10-11-2016 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase A4G23_RS10840 6cc3517befbcb16596c385bef6abe1c0 149 Pfam PF14078 Domain of unknown function (DUF4259) 2 120 1.9E-31 T 10-11-2016 IPR025355 Protein of unknown function DUF4259 A4G23_RS13710 ec67476ec9b823fd25172a68c2ababe4 501 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 10 472 2.0E-177 T 10-11-2016 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0016020 A4G23_RS08885 e0c3eb4d76f894042954a5f94aab9e74 265 Pfam PF01863 Protein of unknown function DUF45 36 250 6.4E-45 T 10-11-2016 IPR002725 Protein of unknown function DUF45 A4G23_RS26765 5d4251dc8106e9b9b944613bad1f8f28 372 Pfam PF13546 DDE superfamily endonuclease 9 184 1.8E-29 T 10-11-2016 A4G23_RS00235 802ccba4fc904b0869c8acc31f6b9387 82 Pfam PF17196 Protein of unknown function (DUF5133) 1 63 2.0E-21 T 10-11-2016 IPR033457 Protein of unknown function DUF5133 A4G23_RS21365 12beea806ab3924c6ae3d524c0f0b4b2 689 Pfam PF14742 N-terminal domain of (some) glycogen debranching enzymes 60 230 1.4E-15 T 10-11-2016 IPR032856 Putative glycogen debranching enzyme, N-terminal A4G23_RS21365 12beea806ab3924c6ae3d524c0f0b4b2 689 SUPERFAMILY SSF48208 256 674 4.88E-22 T 10-11-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 A4G23_RS19900 d0de060164306bfd71ac5aef65028b3c 454 SUPERFAMILY SSF55874 308 410 2.07E-8 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS19900 d0de060164306bfd71ac5aef65028b3c 454 Pfam PF07730 Histidine kinase 171 200 7.0E-6 T 10-11-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A4G23_RS05440 65ba5d0864a96abe14bf6d7f7e42b462 283 Pfam PF14100 Methane oxygenase PmoA 10 278 4.0E-73 T 10-11-2016 IPR029475 Methane oxygenase PmoA A4G23_RS02120 a7c6a18a6050f12372c71928fa38a463 540 SUPERFAMILY SSF52777 242 449 7.78E-6 T 10-11-2016 A4G23_RS02120 a7c6a18a6050f12372c71928fa38a463 540 SUPERFAMILY SSF52777 23 170 2.11E-7 T 10-11-2016 A4G23_RS05795 957b56e5e26cbb4a3eed972e2075d898 215 Pfam PF10056 Uncharacterized conserved protein (DUF2293) 131 215 1.5E-23 T 10-11-2016 IPR018744 Domain of unknown function DUF2293 A4G23_RS03345 4e8bdf3690c9a2fe794e6cad397c60b7 152 Pfam PF10756 Bacterial PH domain 69 139 1.5E-18 T 10-11-2016 IPR019692 Protein of unknown function DUF2581 A4G23_RS03075 28722f68c57ba6163ed72851e79fe306 251 Pfam PF05949 Bacterial protein of unknown function (DUF881) 114 246 2.5E-37 T 10-11-2016 IPR010273 Protein of unknown function DUF881 A4G23_RS17210 08ac5083bd7113bd5ec531c0cfde6eff 116 Pfam PF04149 Domain of unknown function (DUF397) 63 115 8.1E-21 T 10-11-2016 IPR007278 Domain of unknown function DUF397 A4G23_RS17210 08ac5083bd7113bd5ec531c0cfde6eff 116 Pfam PF04149 Domain of unknown function (DUF397) 12 62 2.9E-20 T 10-11-2016 IPR007278 Domain of unknown function DUF397 A4G23_RS18935 670e443c0ab1d3cbb1620790a09a05c2 99 TIGRFAM TIGR02949 anti_SigH_actin: anti-sigma factor, TIGR02949 family 4 85 1.1E-36 T 10-11-2016 IPR014295 Anti-sigma factor A4G23_RS18935 670e443c0ab1d3cbb1620790a09a05c2 99 TIGRFAM TIGR03988 antisig_RsrA: mycothiol system anti-sigma-R factor 10 84 9.2E-31 T 10-11-2016 IPR024020 Anti sigma-R factor, mycothiol system,RsrA A4G23_RS18935 670e443c0ab1d3cbb1620790a09a05c2 99 Pfam PF13490 Putative zinc-finger 11 44 3.6E-8 T 10-11-2016 IPR027383 Putative zinc-finger A4G23_RS12300 e808ee630e1391012c1be28ef1f0a74d 1145 Gene3D G3DSA:3.40.50.300 53 89 5.4E-4 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS12300 e808ee630e1391012c1be28ef1f0a74d 1145 SUPERFAMILY SSF52540 37 121 9.36E-6 T 10-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4G23_RS13655 aae2e49d256c87a19dafa5538c575e6f 126 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 2 115 4.7E-30 T 10-11-2016 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV A4G23_RS18615 f73893768ad44f6ac7d48962547d10e7 200 Pfam PF05076 Suppressor of fused protein (SUFU) 29 194 2.7E-37 T 10-11-2016 IPR020941 Suppressor of fused-like domain Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5610787|Reactome: R-HSA-5632684 A4G23_RS23295 cd911a0ad6a7f22707622c5bb369bf0f 160 Pfam PF04306 Protein of unknown function (DUF456) 21 154 8.1E-25 T 10-11-2016 IPR007403 Protein of unknown function DUF456 A4G23_RS19385 ecff88172299a8ba405f107034895889 243 Gene3D G3DSA:1.25.10.10 123 224 2.2E-9 T 10-11-2016 IPR011989 Armadillo-like helical A4G23_RS19385 ecff88172299a8ba405f107034895889 243 Gene3D G3DSA:1.25.10.10 22 90 2.2E-9 T 10-11-2016 IPR011989 Armadillo-like helical A4G23_RS19385 ecff88172299a8ba405f107034895889 243 SUPERFAMILY SSF48371 21 239 3.17E-13 T 10-11-2016 IPR016024 Armadillo-type fold GO:0005488 A4G23_RS07940 941481c31d2553cda6d70e7ce75c5712 269 Pfam PF11296 Protein of unknown function (DUF3097) 5 265 1.5E-125 T 10-11-2016 IPR021447 Protein of unknown function DUF3097 A4G23_RS04660 2f431eaa4010d00a24e2d4853d53d376 280 Gene3D G3DSA:2.40.260.10 129 271 3.2E-8 T 10-11-2016 IPR023365 Sortase domain A4G23_RS04660 2f431eaa4010d00a24e2d4853d53d376 280 Pfam PF04203 Sortase family 130 268 2.3E-17 T 10-11-2016 IPR005754 Sortase family A4G23_RS04660 2f431eaa4010d00a24e2d4853d53d376 280 SUPERFAMILY SSF63817 121 272 2.62E-15 T 10-11-2016 IPR023365 Sortase domain A4G23_RS23650 81ed9078c2701b8e8d95eb013c110d12 302 Gene3D G3DSA:3.30.420.40 156 245 2.7E-8 T 10-11-2016 A4G23_RS23650 81ed9078c2701b8e8d95eb013c110d12 302 SUPERFAMILY SSF53067 129 257 1.21E-7 T 10-11-2016 A4G23_RS23650 81ed9078c2701b8e8d95eb013c110d12 302 Pfam PF06723 MreB/Mbl protein 65 177 1.5E-9 T 10-11-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 A4G23_RS23650 81ed9078c2701b8e8d95eb013c110d12 302 Gene3D G3DSA:3.30.420.40 25 155 1.2E-6 T 10-11-2016 A4G23_RS01275 251e106a40864d5f78c7d6975ce03419 365 SUPERFAMILY SSF48576 14 319 2.16E-40 T 10-11-2016 IPR008949 Isoprenoid synthase domain A4G23_RS01275 251e106a40864d5f78c7d6975ce03419 365 Gene3D G3DSA:1.10.600.10 6 308 1.1E-61 T 10-11-2016 IPR008949 Isoprenoid synthase domain A4G23_RS05145 1e7006481f01cd5220ab54fca31886d9 66 Pfam PF04149 Domain of unknown function (DUF397) 8 57 1.1E-19 T 10-11-2016 IPR007278 Domain of unknown function DUF397 A4G23_RS27165 3b9f4fd4cecea34962ebadb688e3e1f6 253 Pfam PF14219 Domain of unknown function (DUF4328) 83 233 2.8E-41 T 10-11-2016 IPR025565 Domain of unknown function DUF4328 A4G23_RS05230 ab3bbca0b6fc3f3b89831942bc22d138 297 Pfam PF02104 SURF1 family 19 229 1.2E-32 T 10-11-2016 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4G23_RS02720 1ed74df5a78a95abc79ea798ca9e40d1 1143 Pfam PF12902 Ferritin-like 719 972 9.2E-36 T 10-11-2016 A4G23_RS19660 e72aa9f2306a6d5441d028ece1ae0b01 259 Pfam PF12730 ABC-2 family transporter protein 8 188 1.4E-7 T 10-11-2016 IPR032688 ABC-2 family transporter protein GO:0006810 A4G23_RS10415 7c3e09a8871ba62075e32ef1dacef46e 126 Pfam PF04138 GtrA-like protein 10 120 9.2E-21 T 10-11-2016 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 A4G23_RS02665 5f65ae491cfbac00ec1a3af9dc265b55 470 SUPERFAMILY SSF110849 100 180 9.07E-6 T 10-11-2016 IPR003115 ParB/Sulfiredoxin A4G23_RS07120 b3ad6b0fd1a24cc3d5aaf04bdb79f474 280 Pfam PF02591 C4-type zinc ribbon domain 238 272 3.2E-11 T 10-11-2016 IPR003743 C4-type zinc ribbon domain A4G23_RS17575 77600a341e76298f25858965afadf81a 120 Pfam PF05973 Phage derived protein Gp49-like (DUF891) 14 107 6.3E-20 T 10-11-2016 IPR009241 Toxin HigB-like A4G23_RS14045 6d1c031f1bbea6bc89c3915fb629919a 448 Pfam PF04235 Protein of unknown function (DUF418) 277 433 1.1E-30 T 10-11-2016 IPR007349 Domain of unknown function DUF418 A4G23_RS11760 ebad98014d946e0c461b36efedc03327 422 Gene3D G3DSA:1.20.1250.20 189 384 5.0E-16 T 10-11-2016 A4G23_RS11760 ebad98014d946e0c461b36efedc03327 422 Gene3D G3DSA:1.20.1250.20 5 187 1.1E-28 T 10-11-2016 A4G23_RS11760 ebad98014d946e0c461b36efedc03327 422 Pfam PF07690 Major Facilitator Superfamily 9 331 2.1E-39 T 10-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4G23_RS11760 ebad98014d946e0c461b36efedc03327 422 SUPERFAMILY SSF103473 4 383 2.62E-58 T 10-11-2016 IPR020846 Major facilitator superfamily domain A4G23_RS07355 aee92491e22c0aaa766c5824760c1af8 257 Pfam PF13349 Putative adhesin 124 253 1.1E-12 T 10-11-2016 IPR025164 Putative adhesin A4G23_RS09230 481d5baf797cbfcb1b726386cff45dbe 414 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 82 344 3.8E-56 T 10-11-2016 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 A4G23_RS09230 481d5baf797cbfcb1b726386cff45dbe 414 Gene3D G3DSA:3.40.390.10 219 262 4.1E-5 T 10-11-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 A4G23_RS00205 b6b6c4b026984efe6b3e52689cdcc43c 249 Pfam PF01925 Sulfite exporter TauE/SafE 8 243 8.4E-43 T 10-11-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 A4G23_RS05025 b56a56837bd7dc226c7cefaf7b0ef144 260 Pfam PF07070 SpoOM protein 3 216 9.6E-79 T 10-11-2016 IPR009776 Sporulation stage 0, protein M A4G23_RS06235 1d441d34f2ea48ba0a5a726253013f05 270 Pfam PF08478 POTRA domain, FtsQ-type 68 136 2.9E-18 T 10-11-2016 IPR013685 Polypeptide-transport-associated, FtsQ-type A4G23_RS06235 1d441d34f2ea48ba0a5a726253013f05 270 Hamap MF_00911 Cell division protein FtsQ [ftsQ]. 38 268 18.037 T 10-11-2016 IPR026579 Cell division protein FtsQ GO:0090529 A4G23_RS05805 05dbee7d4fba07fb005c83c3db86233c 411 Pfam PF04434 SWIM zinc finger 137 157 3.7E-7 T 10-11-2016 IPR007527 Zinc finger, SWIM-type GO:0008270 A4G23_RS00735 f76be6e0a4be630df55f224d8401cd5a 328 PIRSF PIRSF035875 1 306 1.8E-91 T 10-11-2016 IPR017039 Virulence factor BrkB A4G23_RS00735 f76be6e0a4be630df55f224d8401cd5a 328 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 28 282 4.5E-33 T 10-11-2016 IPR017039 Virulence factor BrkB A4G23_RS00735 f76be6e0a4be630df55f224d8401cd5a 328 Pfam PF03631 Virulence factor BrkB 29 286 7.8E-66 T 10-11-2016 IPR017039 Virulence factor BrkB A4G23_RS23855 b6e8c3ebb84cbc9c61c56c0f76921f65 66 Pfam PF04149 Domain of unknown function (DUF397) 12 64 3.1E-21 T 10-11-2016 IPR007278 Domain of unknown function DUF397 A4G23_RS25140 7b17287d2fb13af4b23c3b49aa6fc457 123 Pfam PF05331 Protein of unknown function (DUF742) 13 121 8.8E-37 T 10-11-2016 IPR007995 Protein of unknown function DUF742 A4G23_RS05060 ec45e88f8b3f9e294596edc6b8a2e09a 262 ProDom PD040491 SCO1799 RV1486C/MT1533 MB1522C CGL1536 ML1804 MAV321 22 221 3.0E-54 T 10-11-2016 A4G23_RS08180 5b84064a31573c52f03a6f75641f483b 379 SUPERFAMILY SSF89372 25 339 3.73E-16 T 10-11-2016 A4G23_RS24140 b7a5b0172543d2ad63ed0fd0d827c64d 84 Pfam PF11160 Protein of unknown function (DUF2945) 22 82 4.9E-27 T 10-11-2016 IPR021331 Protein of unknown function DUF2945 A4G23_RS15925 1476e1358f0eff3f20fee4d262ce8736 1086 SUPERFAMILY SSF69318 774 1071 1.31E-18 T 10-11-2016 A4G23_RS23610 7d3959985319993a5cc17dbffec59fb1 130 Pfam PF10025 Uncharacterized conserved protein (DUF2267) 3 122 8.9E-30 T 10-11-2016 IPR018727 Protein of unknown function DUF2267 A4G23_RS06505 bebd4364f861a5cda8bf9ce553309e78 454 Pfam PF05991 YacP-like NYN domain 332 452 7.3E-18 T 10-11-2016 IPR010298 Protein of unknown function DUF901 A4G23_RS17775 3b87c7a8ae36cafb01769030a677a425 181 Pfam PF11695 Domain of unknown function (DUF3291) 4 163 1.5E-40 T 10-11-2016 IPR021708 Domain of unknown function DUF3291 A4G23_RS17245 0e45d6de37bae35b1d264950104f1684 349 Pfam PF11222 Protein of unknown function (DUF3017) 253 327 1.4E-16 T 10-11-2016 IPR021385 Protein of unknown function DUF3017 A4G23_RS00520 e07edd41b8b3f0ae04f8d1a36bc05233 84 Pfam PF05121 Gas vesicle protein K 2 84 1.5E-36 T 10-11-2016 IPR007805 Gas vesicle protein GvpK GO:0031412 A4G23_RS18995 e2dabef0f1b1d2b82ea25b54787fc10c 78 Pfam PF11755 Protein of unknown function (DUF3311) 12 69 2.3E-24 T 10-11-2016 IPR021741 Protein of unknown function DUF3311 A4G23_RS14915 69b2e0a667dff84c7e475a5f79b421b4 294 Pfam PF00482 Type II secretion system (T2SS), protein F 126 248 5.5E-9 T 10-11-2016 IPR018076 Type II secretion system F domain A4G23_RS07415 50cce8b18841195faef68edc06fa81b8 145 Pfam PF11253 Protein of unknown function (DUF3052) 15 139 5.3E-57 T 10-11-2016 IPR021412 Protein of unknown function DUF3052 A4G23_RS18105 6934a190de06030876169dc8790599d6 108 Pfam PF07811 TadE-like protein 1 41 5.3E-8 T 10-11-2016 IPR012495 TadE-like A4G23_RS19440 0a0b95ce127031de5847a4002f0848bd 280 Pfam PF13749 Putative ATP-dependent DNA helicase recG C-terminal 193 275 9.5E-19 T 10-11-2016 IPR025831 ATP-dependent DNA helicase RecG, C-terminal domain A4G23_RS05040 e9547fdbfdedfa6296717cb7820f517a 256 Pfam PF01925 Sulfite exporter TauE/SafE 10 252 4.1E-39 T 10-11-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 A4G23_RS25790 bcbaf83322c4eef29e8be6d0a4b9fd73 254 Pfam PF14023 Protein of unknown function (DUF4239) 48 234 6.2E-16 T 10-11-2016 IPR025333 Protein of unknown function DUF4239 A4G23_RS12565 c50cd3c18b25a0d0872f75bd1f907416 264 SUPERFAMILY SSF89392 101 249 3.02E-8 T 10-11-2016 IPR029046 Lipoprotein localisation LolA/LolB/LppX A4G23_RS11340 c7d0482fa8923e73deb7c53a0fcd0d97 521 PIRSF PIRSF006060 20 507 1.6E-50 T 10-11-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A4G23_RS11340 c7d0482fa8923e73deb7c53a0fcd0d97 521 Pfam PF13520 Amino acid permease 43 448 4.9E-27 T 10-11-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A4G23_RS02030 15bb8eb308f7de71ea41a8b2067fb1e7 534 Pfam PF13515 Fusaric acid resistance protein-like 197 322 1.4E-15 T 10-11-2016 A4G23_RS25440 198413b7039e4faba8f3ea09b1202552 428 Pfam PF06081 Aromatic acid exporter family member 1 37 172 1.3E-8 T 10-11-2016 IPR010343 Aromatic acid exporter family member 1 A4G23_RS01180 ff78fad1d59e358f4d2290f049058da1 63 Pfam PF11387 Protein of unknown function (DUF2795) 12 55 9.8E-20 T 10-11-2016 IPR021527 Protein of unknown function DUF2795 A4G23_RS07290 93725cbea5e9c54dce5832039b5a97cc 67 Pfam PF10041 Uncharacterized conserved protein (DUF2277) 3 53 5.0E-17 T 10-11-2016 IPR018735 Protein of unknown function DUF2277 A4G23_RS18390 b5c2ee634c596bff479bcccf336d161e 142 Pfam PF13581 Histidine kinase-like ATPase domain 17 135 2.0E-8 T 10-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain A4G23_RS25705 3ae5479d11c2d8986b7f0c90783c98e5 482 Pfam PF06762 Lipase maturation factor 124 273 2.3E-59 T 10-11-2016 IPR009613 Lipase maturation factor Reactome: R-HSA-192456 A4G23_RS25705 3ae5479d11c2d8986b7f0c90783c98e5 482 Pfam PF06762 Lipase maturation factor 289 469 5.0E-64 T 10-11-2016 IPR009613 Lipase maturation factor Reactome: R-HSA-192456 A4G23_RS14525 e9edc8fd40d0b4688d9f309ce0951a5f 94 Pfam PF07561 Domain of Unknown Function (DUF1540) 9 40 8.5E-6 T 10-11-2016 IPR011437 Domain of unknown function DUF1540 A4G23_RS14525 e9edc8fd40d0b4688d9f309ce0951a5f 94 Pfam PF07561 Domain of Unknown Function (DUF1540) 59 91 1.4E-5 T 10-11-2016 IPR011437 Domain of unknown function DUF1540 A4G23_RS11195 6b840d2cc5836d68eac0b815e791505e 470 Pfam PF03559 NDP-hexose 2,3-dehydratase 42 245 2.0E-85 T 10-11-2016 IPR005212 NDP-hexose 2,3-dehydratase A4G23_RS11195 6b840d2cc5836d68eac0b815e791505e 470 Pfam PF03559 NDP-hexose 2,3-dehydratase 259 463 5.2E-70 T 10-11-2016 IPR005212 NDP-hexose 2,3-dehydratase A4G23_RS12200 6967d6ee5de4291064830657201348fa 221 SUPERFAMILY SSF110087 42 156 1.44E-8 T 10-11-2016 IPR007410 DR1885-like metal-binding protein A4G23_RS01260 d0df50ae5dbb510597eb676fc320a1a8 119 Pfam PF01925 Sulfite exporter TauE/SafE 8 117 9.2E-19 T 10-11-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 A4G23_RS01830 1fa0b196ac6449ea8100e1f0e90a6892 222 Gene3D G3DSA:1.10.340.30 38 150 1.0E-5 T 10-11-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A4G23_RS01830 1fa0b196ac6449ea8100e1f0e90a6892 222 SUPERFAMILY SSF48150 36 190 2.62E-11 T 10-11-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A4G23_RS25685 eea6fda9d88cff2dfe521c76ba6bbc18 74 PRINTS PR01217 Proline rich extensin signature 27 43 1.1E-10 T 10-11-2016 A4G23_RS25685 eea6fda9d88cff2dfe521c76ba6bbc18 74 PRINTS PR01217 Proline rich extensin signature 45 62 1.1E-10 T 10-11-2016 A4G23_RS25685 eea6fda9d88cff2dfe521c76ba6bbc18 74 PRINTS PR01217 Proline rich extensin signature 6 27 1.1E-10 T 10-11-2016 A4G23_RS14465 27db34fc8e641248a097ec9eda2fa231 181 Pfam PF10722 Putative bacterial sensory transduction regulator 31 160 3.1E-15 T 10-11-2016 IPR019660 Putative sensory transduction regulator YbjN A4G23_RS24870 475df8d92d9429bd5287adfe881c13d3 242 Pfam PF01066 CDP-alcohol phosphatidyltransferase 32 96 1.4E-8 T 10-11-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A4G23_RS09650 14d168c12d87b8823d750b596e8f7419 95 Pfam PF11238 Protein of unknown function (DUF3039) 26 81 3.2E-32 T 10-11-2016 IPR021400 Protein of unknown function DUF3039 A4G23_RS05205 5334dbdc72edc41c714fcc3e9933927a 226 Pfam PF07947 YhhN-like protein 33 200 2.0E-33 T 10-11-2016 IPR012506 YhhN-like GO:0016021 A4G23_RS16560 71514909189a6ccd36eb5f85abc6b47b 69 Pfam PF04149 Domain of unknown function (DUF397) 14 66 6.6E-22 T 10-11-2016 IPR007278 Domain of unknown function DUF397 A4G23_RS01120 aca2d78986a013496c977596d784c3db 137 Pfam PF13471 Transglutaminase-like superfamily 24 127 2.4E-12 T 10-11-2016 IPR032708 Microcin J25-processing protein McjB, C-terminal A4G23_RS20365 d5dcba6734688a5e601d41e9caf63d50 163 Pfam PF12028 Protein of unknown function (DUF3515) 24 161 1.9E-25 T 10-11-2016 IPR021903 Protein of unknown function DUF3515 A4G23_RS21520 cd7ca0d5bcfb2d7c8efeafa530fb7d8d 169 Pfam PF11292 Protein of unknown function (DUF3093) 20 158 7.4E-45 T 10-11-2016 IPR021443 Protein of unknown function DUF3093 A4G23_RS20930 b33f73aaaa150879e152f21c3061f024 77 Pfam PF04149 Domain of unknown function (DUF397) 20 70 3.6E-8 T 10-11-2016 IPR007278 Domain of unknown function DUF397 A4G23_RS02875 c0dbdb9e521d3b3b96256a1b604f1cf3 229 Pfam PF09335 SNARE associated Golgi protein 32 160 2.4E-16 T 10-11-2016 IPR032816 SNARE associated Golgi protein A4G23_RS02515 1b1053b23b3dca8a5cefcfbdf70bbc27 882 Pfam PF04738 Lantibiotic dehydratase, C terminus 463 787 2.4E-16 T 10-11-2016 IPR006827 Lantibiotic dehydratase, C-terminal A4G23_RS02905 c17b2c495927b99f64a85e620da93966 238 Pfam PF09335 SNARE associated Golgi protein 80 197 9.5E-27 T 10-11-2016 IPR032816 SNARE associated Golgi protein A4G23_RS09510 aa895d940a7815399080231763b213b1 280 Pfam PF06271 RDD family 127 272 6.8E-23 T 10-11-2016 IPR010432 RDD A4G23_RS15045 251bdabc9fe54b5d3f9cc6e4d65d309a 106 Pfam PF03777 Small secreted domain (DUF320) 23 78 1.7E-26 T 10-11-2016 IPR005528 Domain of unknown function DUF320, Streptomyces species A4G23_RS23235 f4a36090e50f5999868e68c96c81054f 414 Pfam PF00999 Sodium/hydrogen exchanger family 13 367 8.6E-44 T 10-11-2016 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A4G23_RS17780 801b3d88e32ea680d18caaa377b44829 197 Pfam PF10756 Bacterial PH domain 76 130 1.0E-10 T 10-11-2016 IPR019692 Protein of unknown function DUF2581 A4G23_RS12660 d39cdd0588b942f410bc0cfefa3e14e1 245 Pfam PF12679 ABC-2 family transporter protein 34 245 1.5E-6 T 10-11-2016 IPR032688 ABC-2 family transporter protein GO:0006810 A4G23_RS06305 644802a81a4faee3016b5a61717d20b2 131 Pfam PF11239 Protein of unknown function (DUF3040) 1 80 3.2E-29 T 10-11-2016 IPR021401 Protein of unknown function DUF3040 A4G23_RS25695 e8a00ae7d263c1ee50c5534ef4f0ad47 205 Pfam PF11575 FhuF 2Fe-2S C-terminal domain 165 184 2.6E-8 T 10-11-2016 IPR024726 Ferric iron reductase, C-terminal GO:0051537 A4G23_RS17715 534dbdf23bbe513459dc5ba53de8a914 93 Pfam PF03777 Small secreted domain (DUF320) 32 77 2.5E-4 T 10-11-2016 IPR005528 Domain of unknown function DUF320, Streptomyces species A4G23_RS01125 8c8046106e5bf11f9a6697d7842610e6 100 Pfam PF05402 Coenzyme PQQ synthesis protein D (PqqD) 19 81 1.8E-5 T 10-11-2016 IPR008792 Coenzyme PQQ synthesis D A4G23_RS26445 5d539f3fa50e69e5dd6f497c231941a6 198 Pfam PF14065 Protein of unknown function (DUF4255) 9 182 6.3E-40 T 10-11-2016 IPR025351 Protein of unknown function DUF4255 A4G23_RS01775 18d8f4f0066ec9ed2af5af8f34a3d0b9 786 SUPERFAMILY SSF53474 561 682 1.6E-8 T 10-11-2016 IPR029058 Alpha/Beta hydrolase fold A4G23_RS26335 9df4487ab71302c1f69c28ba8458e6b3 697 Pfam PF04738 Lantibiotic dehydratase, C terminus 9 533 7.8E-47 T 10-11-2016 IPR006827 Lantibiotic dehydratase, C-terminal A4G23_RS26335 9df4487ab71302c1f69c28ba8458e6b3 697 Pfam PF04738 Lantibiotic dehydratase, C terminus 562 643 2.5E-14 T 10-11-2016 IPR006827 Lantibiotic dehydratase, C-terminal A4G23_RS21790 0c9bdd1913ccc0093dace9b36d4cd97c 846 Pfam PF02687 FtsX-like permease family 267 387 1.1E-21 T 10-11-2016 IPR003838 ABC transporter permease protein domain GO:0016020 A4G23_RS21790 0c9bdd1913ccc0093dace9b36d4cd97c 846 Pfam PF02687 FtsX-like permease family 725 837 6.4E-9 T 10-11-2016 IPR003838 ABC transporter permease protein domain GO:0016020 A4G23_RS24880 29c89c6ebd4f7114dd1f456b49e7a17e 309 Pfam PF01061 ABC-2 type transporter 61 267 6.2E-16 T 10-11-2016 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A4G23_RS05380 405657797e0d98f4fe6d7bf5e1f64fc1 346 SUPERFAMILY SSF89372 12 275 5.23E-8 T 10-11-2016 A4G23_RS17755 41561c500f1d09e4b6ac9cfbbb14ed11 69 Pfam PF04149 Domain of unknown function (DUF397) 14 66 6.4E-18 T 10-11-2016 IPR007278 Domain of unknown function DUF397 A4G23_RS22210 182ebace00ac777e8210e80ad7b92b53 88 Pfam PF02583 Metal-sensitive transcriptional repressor 9 82 8.6E-25 T 10-11-2016 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 A4G23_RS23945 b34c3a29d24032f81b809f23b3122faf 352 Pfam PF02653 Branched-chain amino acid transport system / permease component 62 337 4.1E-59 T 10-11-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 A4G23_RS02965 141bce194f98166d1fefc0aafa79b2ae 127 Pfam PF11236 Protein of unknown function (DUF3037) 9 126 6.5E-42 T 10-11-2016 IPR021398 Protein of unknown function DUF3037