locus-tag	class	description
SCAB_RS00040	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SCAB_RS00065	COG2801	Transposase and inactivated derivatives
SCAB_RS00175	COG3328	transposase activity
SCAB_RS00220	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SCAB_RS00235	COG1028	Short-chain dehydrogenase reductase Sdr
SCAB_RS00240	COG4948	Mandelate Racemase Muconate Lactonizing
SCAB_RS00245	COG0179	Fumarylacetoacetate (FAA) hydrolase
SCAB_RS00250	COG4948	Mandelate Racemase Muconate Lactonizing
SCAB_RS00260	COG1175	transmembrane transport
SCAB_RS00320	COG3547	Transposase (IS116 IS110 IS902 family)
SCAB_RS00350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SCAB_RS00360	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SCAB_RS00365	COG1280	lysine exporter protein (LysE YggA)
SCAB_RS00405	COG5002	protein histidine kinase activity
SCAB_RS00410	COG1231	oxidoreductase activity
SCAB_RS00425	COG0515	serine threonine protein kinase
SCAB_RS00455	COG3547	Transposase (IS116 IS110 IS902 family)
SCAB_RS00480	COG1136	(ABC) transporter
SCAB_RS00480	COG0577	efflux transmembrane transporter activity
SCAB_RS00485	COG2197	response regulator
SCAB_RS00490	COG4585	Histidine kinase
SCAB_RS00515	COG0483	inositol monophosphate 1-phosphatase activity
SCAB_RS00585	COG2801	Transposase and inactivated derivatives
SCAB_RS00615	COG3629	intracellular signal transduction
SCAB_RS00615	COG3903	Transcriptional regulator
SCAB_RS00635	COG1021	2,3-dihydroxybenzoate-AMP ligase
SCAB_RS00645	COG1132	(ABC) transporter
SCAB_RS00650	COG1132	(ABC) transporter
SCAB_RS00650	COG2375	cellular response to nickel ion
SCAB_RS00665	COG3433	isochorismatase activity
SCAB_RS00665	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SCAB_RS00665	COG2226	methyltransferase
SCAB_RS00670	COG3433	isochorismatase activity
SCAB_RS00670	COG2226	methyltransferase
SCAB_RS00670	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SCAB_RS00685	COG2192	nodulation
SCAB_RS00695	COG0318	PFAM AMP-dependent synthetase and ligase
SCAB_RS00700	COG0318	PFAM AMP-dependent synthetase and ligase
SCAB_RS00705	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SCAB_RS00710	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SCAB_RS00720	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SCAB_RS00755	COG2197	response regulator
SCAB_RS00760	COG1021	2,3-dihydroxybenzoate-AMP ligase
SCAB_RS00865	COG2146	nitrite reductase [NAD(P)H] activity
SCAB_RS00865	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SCAB_RS00870	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SCAB_RS00875	COG0243	molybdopterin cofactor binding
SCAB_RS00885	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
SCAB_RS00890	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
SCAB_RS00905	COG2223	nitrite transmembrane transporter activity
SCAB_RS00915	COG0318	PFAM AMP-dependent synthetase and ligase
SCAB_RS00925	COG0477	Major facilitator Superfamily
SCAB_RS00935	COG4569	acetaldehyde dehydrogenase (acetylating) activity
SCAB_RS00940	COG3971	2-oxopent-4-enoate hydratase activity
SCAB_RS00950	COG1028	Short-chain dehydrogenase reductase Sdr
SCAB_RS00950	COG3321	synthase
SCAB_RS00950	COG0604	alcohol dehydrogenase
SCAB_RS00970	COG2267	carboxylic ester hydrolase activity
SCAB_RS00985	COG2146	nitrite reductase [NAD(P)H] activity
SCAB_RS00995	COG1414	Transcriptional regulator
SCAB_RS01005	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SCAB_RS01085	COG0395	ABC-type sugar transport system, permease component
SCAB_RS01110	COG3224	Antibiotic biosynthesis monooxygenase
SCAB_RS01115	COG0590	tRNA wobble adenosine to inosine editing
SCAB_RS01145	COG0477	Major facilitator Superfamily
SCAB_RS01170	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SCAB_RS01195	COG1309	transcriptional regulator
SCAB_RS01205	COG0154	amidase activity
SCAB_RS01210	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SCAB_RS01215	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
SCAB_RS01220	COG2205	protein histidine kinase activity
SCAB_RS01225	COG0745	RESPONSE REGULATOR receiver
SCAB_RS01250	COG1132	(ABC) transporter
SCAB_RS01255	COG4585	Histidine kinase
SCAB_RS01260	COG2197	response regulator
SCAB_RS01315	COG4249	Peptidase C14 caspase catalytic subunit p20
SCAB_RS01315	COG2319	Wd-40 repeat
SCAB_RS01380	COG2814	Major facilitator Superfamily
SCAB_RS01390	COG3848	Pyruvate phosphate dikinase
SCAB_RS01390	COG0574	Belongs to the PEP-utilizing enzyme family
SCAB_RS01405	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SCAB_RS01465	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SCAB_RS01480	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SCAB_RS01495	COG0318	PFAM AMP-dependent synthetase and ligase
SCAB_RS01500	COG1960	acyl-CoA dehydrogenase activity
SCAB_RS01510	COG3320	Male sterility
SCAB_RS01510	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SCAB_RS01535	COG2175	clavaminate synthase activity
SCAB_RS01540	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SCAB_RS01545	COG0667	Aldo Keto reductase
SCAB_RS01555	COG1733	regulation of RNA biosynthetic process
SCAB_RS01580	COG0563	adenylate kinase activity
SCAB_RS01605	COG1621	beta-fructofuranosidase activity
SCAB_RS01615	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
SCAB_RS01650	COG2186	Transcriptional regulator
SCAB_RS01655	COG0473	3-isopropylmalate dehydrogenase activity
SCAB_RS01660	COG0539	negative regulation of cytoplasmic translation
SCAB_RS01665	COG2319	Wd-40 repeat
SCAB_RS01665	COG4249	Peptidase C14 caspase catalytic subunit p20
SCAB_RS01675	COG0515	serine threonine protein kinase
SCAB_RS01680	COG1132	(ABC) transporter
SCAB_RS01685	COG1132	(ABC) transporter
SCAB_RS01690	COG1028	Short-chain dehydrogenase reductase Sdr
SCAB_RS01765	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SCAB_RS01770	COG1012	belongs to the aldehyde dehydrogenase family
SCAB_RS01795	COG3345	alpha-galactosidase
SCAB_RS01810	COG1595	DNA-templated transcription, initiation
SCAB_RS01815	COG1252	NADH dehydrogenase
SCAB_RS01855	COG2205	protein histidine kinase activity
SCAB_RS01860	COG0745	RESPONSE REGULATOR receiver
SCAB_RS01905	COG2200	EAL domain
SCAB_RS01905	COG2202	Pas domain
SCAB_RS01905	COG2199	diguanylate cyclase activity
SCAB_RS01940	COG1063	alcohol dehydrogenase
SCAB_RS01945	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
SCAB_RS01950	COG2326	polyphosphate kinase activity
SCAB_RS01990	COG0702	epimerase
SCAB_RS02005	COG1595	DNA-templated transcription, initiation
SCAB_RS02030	COG1295	ribonuclease BN
SCAB_RS02045	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SCAB_RS02050	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
SCAB_RS02055	COG2080	2 iron, 2 sulfur cluster binding
SCAB_RS02100	COG1653	transport
SCAB_RS02165	COG2018	Roadblock/LC7 domain
SCAB_RS02170	COG5002	protein histidine kinase activity
SCAB_RS02185	COG4977	sequence-specific DNA binding
SCAB_RS02245	COG0577	efflux transmembrane transporter activity
SCAB_RS02245	COG1136	(ABC) transporter
SCAB_RS02265	COG1028	Short-chain dehydrogenase reductase Sdr
SCAB_RS02275	COG0515	serine threonine protein kinase
SCAB_RS02275	COG2815	serine threonine protein kinase
SCAB_RS02285	COG2318	DinB family
SCAB_RS02290	COG1132	(ABC) transporter
SCAB_RS02295	COG5520	Belongs to the glycosyl hydrolase 30 family
SCAB_RS02335	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SCAB_RS02415	COG4172	Belongs to the ABC transporter superfamily
SCAB_RS02420	COG4171	peptide transport system, permease
SCAB_RS02425	COG0601	transmembrane transport
SCAB_RS02445	COG0019	diaminopimelate decarboxylase activity
SCAB_RS02450	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SCAB_RS02460	COG1609	Transcriptional regulator
SCAB_RS02525	COG0142	geranyltranstransferase activity
SCAB_RS02545	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
SCAB_RS02560	COG2188	Transcriptional regulator
SCAB_RS02585	COG2197	response regulator
SCAB_RS02590	COG4585	Histidine kinase
SCAB_RS02615	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SCAB_RS02660	COG1028	Short-chain dehydrogenase reductase Sdr
SCAB_RS02700	COG1609	Transcriptional regulator
SCAB_RS02725	COG2851	Citrate transporter
SCAB_RS02730	COG0583	DNA-binding transcription factor activity
SCAB_RS02735	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SCAB_RS02805	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SCAB_RS02815	COG2197	response regulator
SCAB_RS02820	COG4585	Histidine kinase
SCAB_RS02860	COG2326	polyphosphate kinase activity
SCAB_RS02905	COG1366	Belongs to the anti-sigma-factor antagonist family
SCAB_RS02910	COG2208	phosphoserine phosphatase activity
SCAB_RS02910	COG2770	Histidine kinase
SCAB_RS02915	COG0596	Alpha beta hydrolase
SCAB_RS02965	COG5640	endopeptidase activity
SCAB_RS03015	COG1129	ABC transporter
SCAB_RS03020	COG1172	Belongs to the binding-protein-dependent transport system permease family
SCAB_RS03025	COG4948	Mandelate Racemase Muconate Lactonizing
SCAB_RS03030	COG3618	amidohydrolase
SCAB_RS03040	COG1063	alcohol dehydrogenase
SCAB_RS03045	COG1028	Short-chain dehydrogenase reductase Sdr
SCAB_RS03050	COG0800	Aldolase
SCAB_RS03065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SCAB_RS03075	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
SCAB_RS03085	COG0183	Belongs to the thiolase family
SCAB_RS03090	COG0583	DNA-binding transcription factor activity
SCAB_RS03105	COG0318	PFAM AMP-dependent synthetase and ligase
SCAB_RS03110	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SCAB_RS03110	COG2308	Evidence 4 Homologs of previously reported genes of
SCAB_RS03130	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SCAB_RS03130	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SCAB_RS03130	COG1703	isobutyryl-CoA mutase activity
SCAB_RS03170	COG4171	peptide transport system, permease
SCAB_RS03180	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
SCAB_RS03185	COG1760	l-serine dehydratase
SCAB_RS03190	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SCAB_RS03220	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SCAB_RS03240	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SCAB_RS03255	COG4176	ABC-type proline glycine betaine transport system permease component
SCAB_RS03260	COG0517	IMP dehydrogenase activity
SCAB_RS03260	COG4175	Glycine betaine
SCAB_RS03265	COG1012	belongs to the aldehyde dehydrogenase family
SCAB_RS03280	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
SCAB_RS03290	COG4638	Rieske (2fe-2S)
SCAB_RS03295	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SCAB_RS03305	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SCAB_RS03345	COG1131	(ABC) transporter
SCAB_RS03360	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
SCAB_RS03365	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
SCAB_RS03370	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
SCAB_RS03385	COG1609	Transcriptional regulator
SCAB_RS03420	COG1609	Transcriptional regulator
SCAB_RS03435	COG0395	ABC-type sugar transport system, permease component
SCAB_RS03460	COG3655	Transcriptional regulator
SCAB_RS03470	COG2226	methyltransferase
SCAB_RS03500	COG0513	Belongs to the DEAD box helicase family
SCAB_RS03545	COG0181	hydroxymethylbilane synthase activity
SCAB_RS03560	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
SCAB_RS03585	COG2409	Drug exporters of the RND superfamily
SCAB_RS03620	COG2197	response regulator
SCAB_RS03625	COG4585	Histidine kinase
SCAB_RS03635	COG3290	protein histidine kinase activity
SCAB_RS03670	COG0009	L-threonylcarbamoyladenylate synthase
SCAB_RS03700	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SCAB_RS03710	COG4565	transcriptional regulatory protein
SCAB_RS03715	COG3290	protein histidine kinase activity
SCAB_RS03750	COG0589	response to stress
SCAB_RS03760	COG0492	ferredoxin-NADP+ reductase activity
SCAB_RS03775	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SCAB_RS03780	COG0402	S-adenosylhomocysteine deaminase activity
SCAB_RS03820	COG2340	Cysteine-rich secretory protein family
SCAB_RS03835	COG0572	uridine kinase
SCAB_RS03845	COG0395	ABC-type sugar transport system, permease component
SCAB_RS03860	COG1940	carbohydrate kinase activity
SCAB_RS03885	COG3851	Histidine kinase
SCAB_RS03890	COG2197	response regulator
SCAB_RS03920	COG1940	carbohydrate kinase activity
SCAB_RS03920	COG1846	Transcriptional regulator
SCAB_RS03935	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SCAB_RS03955	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SCAB_RS03965	COG3224	Antibiotic biosynthesis monooxygenase
SCAB_RS03995	COG1132	(ABC) transporter
SCAB_RS04040	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
SCAB_RS04055	COG0515	serine threonine protein kinase
SCAB_RS04065	COG1132	(ABC) transporter
SCAB_RS04070	COG1132	(ABC) transporter
SCAB_RS04115	COG0747	negative chemotaxis
SCAB_RS04125	COG0248	Ppx GppA phosphatase
SCAB_RS04200	COG2197	response regulator
SCAB_RS04215	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SCAB_RS04225	COG2197	response regulator
SCAB_RS04235	COG1129	ABC transporter
SCAB_RS04240	COG1172	Belongs to the binding-protein-dependent transport system permease family
SCAB_RS04255	COG1846	Transcriptional regulator
SCAB_RS04275	COG0435	Glutathione S-transferase
SCAB_RS04305	COG1012	belongs to the aldehyde dehydrogenase family
SCAB_RS04320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SCAB_RS04340	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
SCAB_RS04340	COG1796	DNA polymerase
SCAB_RS04345	COG0546	phosphoglycolate phosphatase activity
SCAB_RS04380	COG2706	6-phosphogluconolactonase activity
SCAB_RS04390	COG1309	transcriptional regulator
SCAB_RS04400	COG1357	PFAM Pentapeptide repeats (8 copies)
SCAB_RS04420	COG1609	Transcriptional regulator
SCAB_RS04435	COG1879	ABC-type sugar transport system periplasmic component
SCAB_RS04440	COG1172	Belongs to the binding-protein-dependent transport system permease family
SCAB_RS04450	COG1129	ABC transporter
SCAB_RS04460	COG3347	Dehydrogenase
SCAB_RS04460	COG1028	Short-chain dehydrogenase reductase Sdr
SCAB_RS04465	COG1070	Carbohydrate kinase
SCAB_RS04470	COG0247	lactate metabolic process
SCAB_RS04475	COG1139	Iron-sulfur cluster binding protein
SCAB_RS04480	COG1556	Lactate utilization protein
SCAB_RS04490	COG1573	uracil-dna glycosylase
SCAB_RS04500	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
SCAB_RS04505	COG0243	molybdopterin cofactor binding
SCAB_RS04510	COG0300	oxidoreductase activity
SCAB_RS04520	COG1028	Short-chain dehydrogenase reductase Sdr
SCAB_RS04525	COG1063	alcohol dehydrogenase
SCAB_RS04535	COG0673	inositol 2-dehydrogenase activity
SCAB_RS04545	COG3708	Transcriptional regulator
SCAB_RS04545	COG2207	Transcriptional regulator
SCAB_RS04555	COG1595	DNA-templated transcription, initiation
SCAB_RS04565	COG0174	glutamine synthetase
SCAB_RS04580	COG4689	acetoacetate decarboxylase
SCAB_RS04595	COG0179	Fumarylacetoacetate (FAA) hydrolase
SCAB_RS04600	COG1309	transcriptional regulator
SCAB_RS04610	COG1012	belongs to the aldehyde dehydrogenase family
SCAB_RS04615	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SCAB_RS04625	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SCAB_RS04645	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
SCAB_RS04655	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
SCAB_RS04660	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SCAB_RS04695	COG1404	Belongs to the peptidase S8 family
SCAB_RS04750	COG2197	response regulator
SCAB_RS04780	COG0768	penicillin binding
SCAB_RS04810	COG2755	lipolytic protein G-D-S-L family
SCAB_RS04920	COG0516	GMP reductase activity
SCAB_RS04920	COG0517	IMP dehydrogenase activity
SCAB_RS04935	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
SCAB_RS04940	COG1937	Protein conserved in bacteria
SCAB_RS04970	COG0516	GMP reductase activity
SCAB_RS04970	COG0517	IMP dehydrogenase activity
SCAB_RS04975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SCAB_RS04975	COG1042	CoA-binding domain protein
SCAB_RS04975	COG0045	succinate-CoA ligase (ADP-forming) activity
SCAB_RS04990	COG0517	IMP dehydrogenase activity
SCAB_RS04990	COG0516	GMP reductase activity
SCAB_RS05000	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SCAB_RS05015	COG1063	alcohol dehydrogenase
SCAB_RS05035	COG0574	Belongs to the PEP-utilizing enzyme family
SCAB_RS05035	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SCAB_RS05070	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SCAB_RS05095	COG1140	nitrate reductase beta subunit
SCAB_RS05100	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
SCAB_RS05140	COG0745	RESPONSE REGULATOR receiver
SCAB_RS05145	COG2205	protein histidine kinase activity
SCAB_RS05150	COG1595	DNA-templated transcription, initiation
SCAB_RS05185	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SCAB_RS05190	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SCAB_RS05210	COG2824	Alkylphosphonate utilization operon protein PhnA
SCAB_RS05215	COG0659	secondary active sulfate transmembrane transporter activity
SCAB_RS05230	COG1484	DNA-dependent DNA replication
SCAB_RS05250	COG0242	peptide deformylase activity
SCAB_RS05260	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SCAB_RS05270	COG1609	Transcriptional regulator
SCAB_RS05295	COG2268	Band 7 protein
SCAB_RS05310	COG3572	ergothioneine biosynthetic process
SCAB_RS05315	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SCAB_RS05320	COG0121	glutamine amidotransferase
SCAB_RS05325	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
SCAB_RS05330	COG3360	Dodecin
SCAB_RS05355	COG2072	flavoprotein involved in K transport
SCAB_RS05360	COG1028	Short-chain dehydrogenase reductase Sdr
SCAB_RS05380	COG0745	RESPONSE REGULATOR receiver
SCAB_RS05385	COG1028	Short-chain dehydrogenase reductase Sdr
SCAB_RS05390	COG2205	protein histidine kinase activity
SCAB_RS05395	COG0745	RESPONSE REGULATOR receiver
SCAB_RS05410	COG1477	protein flavinylation
SCAB_RS05425	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SCAB_RS05440	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SCAB_RS05445	COG1053	succinate dehydrogenase
SCAB_RS05455	COG0583	DNA-binding transcription factor activity
SCAB_RS05505	COG0589	response to stress
SCAB_RS05530	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SCAB_RS05580	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SCAB_RS05585	COG0297	glycogen (starch) synthase activity
SCAB_RS05605	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
SCAB_RS05620	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
SCAB_RS05635	COG1834	amidinotransferase
SCAB_RS05650	COG0277	FAD linked oxidase domain protein
SCAB_RS05670	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SCAB_RS05670	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SCAB_RS05715	COG1028	Short-chain dehydrogenase reductase Sdr
SCAB_RS05760	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SCAB_RS05765	COG0655	NAD(P)H dehydrogenase (quinone) activity
SCAB_RS05775	COG4166	transmembrane transport
SCAB_RS05785	COG1132	(ABC) transporter
SCAB_RS05795	COG0668	transmembrane transport
SCAB_RS05800	COG2838	Isocitrate dehydrogenase
SCAB_RS05805	COG1846	Transcriptional regulator
SCAB_RS05820	COG3345	alpha-galactosidase
SCAB_RS05845	COG3629	intracellular signal transduction
SCAB_RS05845	COG3903	Transcriptional regulator
SCAB_RS05855	COG0641	radical SAM
SCAB_RS05865	COG1454	alcohol dehydrogenase
SCAB_RS05880	COG3284	Transcriptional regulator
SCAB_RS05905	COG2267	carboxylic ester hydrolase activity
SCAB_RS05920	COG0402	S-adenosylhomocysteine deaminase activity
SCAB_RS05925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SCAB_RS05930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SCAB_RS05940	COG1126	abc transporter atp-binding protein
SCAB_RS05955	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SCAB_RS05960	COG3387	PFAM Glycoside hydrolase 15-related
SCAB_RS05970	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SCAB_RS05985	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SCAB_RS05990	COG3938	Belongs to the proline racemase family
SCAB_RS06020	COG0583	DNA-binding transcription factor activity
SCAB_RS06025	COG0156	8-amino-7-oxononanoate synthase activity
SCAB_RS06030	COG1063	alcohol dehydrogenase
SCAB_RS06065	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SCAB_RS06075	COG0300	oxidoreductase activity
SCAB_RS06090	COG0657	acetylesterase activity
SCAB_RS06095	COG0456	acetyltransferase
SCAB_RS06095	COG1846	Transcriptional regulator
SCAB_RS06100	COG2755	lipolytic protein G-D-S-L family
SCAB_RS06120	COG2365	Tyrosine phosphatase family
SCAB_RS06140	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SCAB_RS06145	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SCAB_RS06160	COG1657	PFAM Prenyltransferase squalene oxidase
SCAB_RS06170	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SCAB_RS06180	COG1562	ergosterol biosynthetic process
SCAB_RS06185	COG1134	teichoic acid transport
SCAB_RS06205	COG0371	Dehydrogenase
SCAB_RS06235	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
SCAB_RS06245	COG1024	Enoyl-CoA hydratase
SCAB_RS06255	COG4977	sequence-specific DNA binding
SCAB_RS06265	COG2183	response to ionizing radiation
SCAB_RS06270	COG0488	(ABC) transporter
SCAB_RS06285	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SCAB_RS06295	COG1869	D-ribose catabolic process
SCAB_RS06300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SCAB_RS06310	COG1172	Belongs to the binding-protein-dependent transport system permease family
SCAB_RS06315	COG1879	ABC-type sugar transport system periplasmic component
SCAB_RS06330	COG2936	dipeptidyl-peptidase activity
SCAB_RS06335	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SCAB_RS06345	COG1024	Enoyl-CoA hydratase
SCAB_RS06345	COG1250	3-hydroxyacyl-CoA dehydrogenase
SCAB_RS06350	COG0183	Belongs to the thiolase family
SCAB_RS06355	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SCAB_RS06360	COG3268	Saccharopine dehydrogenase
SCAB_RS06370	COG1515	deoxyribonuclease V activity
SCAB_RS06385	COG0488	(ABC) transporter
SCAB_RS06390	COG1834	amidinotransferase
SCAB_RS06465	COG1793	dna ligase
SCAB_RS06485	COG3485	protocatechuate 3,4-dioxygenase
SCAB_RS06490	COG3485	protocatechuate 3,4-dioxygenase
SCAB_RS06495	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SCAB_RS06500	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SCAB_RS06505	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SCAB_RS06505	COG1672	PFAM Archaeal ATPase
SCAB_RS06535	COG3511	phospholipase C
SCAB_RS06585	COG1028	Short-chain dehydrogenase reductase Sdr
SCAB_RS06600	COG1960	acyl-CoA dehydrogenase activity
SCAB_RS06625	COG1063	alcohol dehydrogenase
SCAB_RS06660	COG1063	alcohol dehydrogenase
SCAB_RS06695	COG1454	alcohol dehydrogenase
SCAB_RS06700	COG3485	protocatechuate 3,4-dioxygenase
SCAB_RS06705	COG3547	Transposase (IS116 IS110 IS902 family)
SCAB_RS06710	COG0154	amidase activity
SCAB_RS06715	COG4166	transmembrane transport
SCAB_RS06720	COG0601	transmembrane transport
SCAB_RS06725	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SCAB_RS06745	COG1021	2,3-dihydroxybenzoate-AMP ligase
SCAB_RS06785	COG3547	Transposase (IS116 IS110 IS902 family)
SCAB_RS06790	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SCAB_RS06795	COG2197	response regulator
SCAB_RS06800	COG4585	Histidine kinase
SCAB_RS06815	COG2205	protein histidine kinase activity
SCAB_RS06820	COG0745	RESPONSE REGULATOR receiver
SCAB_RS06825	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SCAB_RS06840	COG2205	protein histidine kinase activity
SCAB_RS06845	COG0745	RESPONSE REGULATOR receiver
SCAB_RS06910	COG3293	Transposase
SCAB_RS06940	COG1960	acyl-CoA dehydrogenase activity
SCAB_RS06955	COG1028	Short-chain dehydrogenase reductase Sdr
SCAB_RS06980	COG0657	acetylesterase activity
SCAB_RS07040	COG1231	oxidoreductase activity
SCAB_RS07070	COG0477	Major facilitator Superfamily
SCAB_RS07080	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SCAB_RS07155	COG4101	3-hydroxyanthranilate 3,4-dioxygenase activity
SCAB_RS07170	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SCAB_RS07175	COG4569	acetaldehyde dehydrogenase (acetylating) activity
SCAB_RS07180	COG3971	2-oxopent-4-enoate hydratase activity
SCAB_RS07190	COG1113	amino acid transport
SCAB_RS07195	COG3844	kynureninase activity
SCAB_RS07235	COG1414	Transcriptional regulator
SCAB_RS07245	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SCAB_RS07250	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SCAB_RS07295	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
SCAB_RS07310	COG1486	melibiose metabolic process
SCAB_RS07315	COG1349	DNA-binding transcription factor activity
SCAB_RS07320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SCAB_RS07335	COG0395	ABC-type sugar transport system, permease component
SCAB_RS07340	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
SCAB_RS07345	COG3250	beta-galactosidase activity
SCAB_RS07350	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
SCAB_RS07390	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SCAB_RS07400	COG0765	amino acid transport
SCAB_RS07425	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SCAB_RS07440	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
SCAB_RS07450	COG3185	4-Hydroxyphenylpyruvate dioxygenase
SCAB_RS07450	COG1082	Xylose isomerase domain protein TIM barrel
SCAB_RS07455	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SCAB_RS07465	COG0477	Major facilitator Superfamily
SCAB_RS07485	COG0477	Major facilitator Superfamily
SCAB_RS07515	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SCAB_RS07535	COG0438	transferase activity, transferring glycosyl groups
SCAB_RS07550	COG1183	phosphatidylcholine synthase activity
SCAB_RS07560	COG4977	sequence-specific DNA binding
SCAB_RS07570	COG1028	Short-chain dehydrogenase reductase Sdr
SCAB_RS07575	COG0673	inositol 2-dehydrogenase activity
SCAB_RS07620	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
SCAB_RS07655	COG1396	sequence-specific DNA binding
SCAB_RS07685	COG4106	trans-aconitate 2-methyltransferase activity
SCAB_RS07695	COG1401	restriction endodeoxyribonuclease activity
SCAB_RS07720	COG1401	restriction endodeoxyribonuclease activity
SCAB_RS07730	COG0210	DNA helicase
SCAB_RS07795	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SCAB_RS07810	COG1012	belongs to the aldehyde dehydrogenase family
SCAB_RS07820	COG0045	succinate-CoA ligase (ADP-forming) activity
SCAB_RS07830	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SCAB_RS07840	COG2223	nitrite transmembrane transporter activity
SCAB_RS07850	COG3293	Transposase
SCAB_RS07900	COG0673	inositol 2-dehydrogenase activity
SCAB_RS07910	COG1172	Belongs to the binding-protein-dependent transport system permease family
SCAB_RS07915	COG1129	ABC transporter
SCAB_RS07920	COG1940	carbohydrate kinase activity
SCAB_RS07930	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SCAB_RS07955	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SCAB_RS07960	COG3383	formate dehydrogenase (NAD+) activity
SCAB_RS07975	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
SCAB_RS07995	COG1022	Amp-dependent synthetase and ligase
SCAB_RS08005	COG0656	L-ascorbic acid biosynthetic process
SCAB_RS08025	COG5297	Belongs to the glycosyl hydrolase family 6
SCAB_RS08030	COG5297	Belongs to the glycosyl hydrolase family 6
SCAB_RS08030	COG4733	cellulase activity
SCAB_RS08045	COG3401	FG-GAP repeat protein
SCAB_RS08050	COG2226	methyltransferase
SCAB_RS08055	COG2154	pterin-4-alpha-carbinolamine dehydratase
SCAB_RS08070	COG0443	Heat shock 70 kDa protein
SCAB_RS08090	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SCAB_RS08120	COG0028	Belongs to the TPP enzyme family
SCAB_RS08130	COG0693	protein deglycase activity
SCAB_RS08150	COG0488	(ABC) transporter
SCAB_RS08220	COG3285	dna ligase
SCAB_RS08220	COG1793	dna ligase
SCAB_RS08225	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SCAB_RS08235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SCAB_RS08255	COG1619	proteins homologs of microcin C7 resistance protein MccF
SCAB_RS08260	COG4946	Tricorn protease homolog
SCAB_RS08260	COG1506	peptidase
SCAB_RS08260	COG0823	Involved in the tonB-independent uptake of proteins
SCAB_RS08265	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SCAB_RS08270	COG2362	D-Aminopeptidase
SCAB_RS08275	COG2226	methyltransferase
SCAB_RS08315	COG1250	3-hydroxyacyl-CoA dehydrogenase
SCAB_RS08325	COG0604	alcohol dehydrogenase
SCAB_RS08330	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SCAB_RS08330	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SCAB_RS08345	COG1960	acyl-CoA dehydrogenase activity
SCAB_RS08350	COG0688	phosphatidylethanolamine metabolic process
SCAB_RS08365	COG1929	Belongs to the glycerate kinase type-1 family
SCAB_RS08385	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
SCAB_RS08420	COG0640	Transcriptional regulator
SCAB_RS08430	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
SCAB_RS08465	COG1082	Xylose isomerase domain protein TIM barrel
SCAB_RS08470	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SCAB_RS08480	COG0483	inositol monophosphate 1-phosphatase activity
SCAB_RS08490	COG2226	methyltransferase
SCAB_RS08500	COG1953	Uracil, thiamine, allantoin
SCAB_RS08510	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SCAB_RS08525	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SCAB_RS08550	COG0405	Gamma-glutamyltransferase
SCAB_RS08565	COG1126	abc transporter atp-binding protein
SCAB_RS08590	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SCAB_RS08600	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SCAB_RS08610	COG1940	carbohydrate kinase activity
SCAB_RS08615	COG2188	Transcriptional regulator
SCAB_RS08620	COG0673	inositol 2-dehydrogenase activity
SCAB_RS08630	COG2197	response regulator
SCAB_RS08635	COG0667	Aldo Keto reductase
SCAB_RS08655	COG4266	Belongs to the allantoicase family
SCAB_RS08660	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SCAB_RS08665	COG1414	Transcriptional regulator
SCAB_RS08680	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
SCAB_RS08700	COG4264	IucA IucC family
SCAB_RS08715	COG1733	regulation of RNA biosynthetic process
SCAB_RS08720	COG0436	Aminotransferase
SCAB_RS08765	COG2351	hydroxyisourate hydrolase activity
SCAB_RS08785	COG3622	Belongs to the hyi family
SCAB_RS08790	COG2084	Dehydrogenase
SCAB_RS08795	COG3960	tartronate-semialdehyde synthase activity
SCAB_RS08805	COG0318	PFAM AMP-dependent synthetase and ligase
SCAB_RS08810	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SCAB_RS08815	COG2197	response regulator
SCAB_RS08835	COG0598	Magnesium transport protein CorA
SCAB_RS08860	COG3507	Belongs to the glycosyl hydrolase 43 family
SCAB_RS08865	COG0395	ABC-type sugar transport system, permease component
SCAB_RS08870	COG1175	transmembrane transport
SCAB_RS08895	COG1609	Transcriptional regulator
SCAB_RS08910	COG4585	Histidine kinase
SCAB_RS08920	COG2936	dipeptidyl-peptidase activity
SCAB_RS08935	COG0657	acetylesterase activity
SCAB_RS08955	COG3467	pyridoxamine 5'-phosphate
SCAB_RS08960	COG0515	serine threonine protein kinase
SCAB_RS08985	COG0641	radical SAM
SCAB_RS09010	COG3962	Belongs to the TPP enzyme family
SCAB_RS09015	COG2188	Transcriptional regulator
SCAB_RS09020	COG0673	inositol 2-dehydrogenase activity
SCAB_RS09025	COG1609	Transcriptional regulator
SCAB_RS09030	COG0596	Alpha beta hydrolase
SCAB_RS09050	COG0395	ABC-type sugar transport system, permease component
SCAB_RS09055	COG1175	transmembrane transport
SCAB_RS09065	COG0673	inositol 2-dehydrogenase activity
SCAB_RS09090	COG2252	PERMEase
SCAB_RS09095	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SCAB_RS09120	COG1802	Transcriptional regulator
SCAB_RS09155	COG1162	GTPase activity
SCAB_RS09160	COG2267	carboxylic ester hydrolase activity
SCAB_RS09180	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SCAB_RS09185	COG0277	FAD linked oxidase domain protein
SCAB_RS09200	COG1175	transmembrane transport
SCAB_RS09205	COG0395	ABC-type sugar transport system, permease component
SCAB_RS09245	COG2755	lipolytic protein G-D-S-L family
SCAB_RS09270	COG0531	amino acid
SCAB_RS09275	COG2040	homocysteine
SCAB_RS09285	COG1609	Transcriptional regulator
SCAB_RS09315	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SCAB_RS09330	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SCAB_RS09335	COG1960	acyl-CoA dehydrogenase activity
SCAB_RS09360	COG0175	sulfate reduction
SCAB_RS09365	COG0529	Catalyzes the synthesis of activated sulfate
SCAB_RS09390	COG1116	anion transmembrane transporter activity
SCAB_RS09395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SCAB_RS09415	COG2409	Drug exporters of the RND superfamily
SCAB_RS09505	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SCAB_RS09525	COG1404	Belongs to the peptidase S8 family
SCAB_RS09620	COG1960	acyl-CoA dehydrogenase activity
SCAB_RS09630	COG2018	Roadblock/LC7 domain
SCAB_RS09640	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SCAB_RS09665	COG1609	Transcriptional regulator
SCAB_RS09685	COG0456	acetyltransferase
SCAB_RS09695	COG3629	intracellular signal transduction
SCAB_RS09695	COG3903	Transcriptional regulator
SCAB_RS09700	COG3629	intracellular signal transduction
SCAB_RS09700	COG3903	Transcriptional regulator
SCAB_RS09715	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SCAB_RS09720	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SCAB_RS09750	COG0330	HflC and HflK could
SCAB_RS09775	COG0726	polysaccharide deacetylase
SCAB_RS09810	COG3220	belongs to the UPF0276 family
SCAB_RS09830	COG3253	May function as heme-dependent peroxidase
SCAB_RS09835	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SCAB_RS09845	COG0446	pyridine nucleotide-disulphide oxidoreductase
SCAB_RS09860	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
SCAB_RS09875	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
SCAB_RS09880	COG0395	ABC-type sugar transport system, permease component
SCAB_RS09885	COG1175	transmembrane transport
SCAB_RS09890	COG2182	Extracellular solute-binding protein
SCAB_RS09900	COG1609	Transcriptional regulator
SCAB_RS09905	COG0183	Belongs to the thiolase family
SCAB_RS09910	COG1024	Enoyl-CoA hydratase
SCAB_RS09910	COG1250	3-hydroxyacyl-CoA dehydrogenase
SCAB_RS09920	COG0531	amino acid
SCAB_RS09925	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SCAB_RS09930	COG4214	carbohydrate transport
SCAB_RS09940	COG4213	ABC transporter substrate-binding protein
SCAB_RS09945	COG1940	carbohydrate kinase activity
SCAB_RS09950	COG0395	ABC-type sugar transport system, permease component
SCAB_RS09955	COG1175	transmembrane transport
SCAB_RS09960	COG1653	transport
SCAB_RS09980	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
SCAB_RS09995	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SCAB_RS10050	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SCAB_RS10060	COG1111	helicase
SCAB_RS10060	COG1205	dead DEAH box helicase
SCAB_RS10130	COG1434	Gram-negative-bacterium-type cell wall biogenesis
SCAB_RS10160	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SCAB_RS10220	COG0174	glutamine synthetase
SCAB_RS10260	COG0154	amidase activity
SCAB_RS10355	COG4106	trans-aconitate 2-methyltransferase activity
SCAB_RS10380	COG3547	Transposase (IS116 IS110 IS902 family)
SCAB_RS10435	COG0738	Major facilitator superfamily
SCAB_RS10440	COG0151	Belongs to the GarS family
SCAB_RS10755	COG3250	beta-galactosidase activity
SCAB_RS10775	COG3250	beta-galactosidase activity
SCAB_RS10790	COG0318	PFAM AMP-dependent synthetase and ligase
SCAB_RS10800	COG1609	Transcriptional regulator
SCAB_RS10810	COG0596	Alpha beta hydrolase
SCAB_RS10830	COG2197	response regulator
SCAB_RS10865	COG0475	glutathione-regulated potassium exporter activity
SCAB_RS10870	COG2268	Band 7 protein
SCAB_RS10875	COG1585	Membrane protein implicated in regulation of membrane protease activity
SCAB_RS10940	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SCAB_RS10945	COG2235	arginine
SCAB_RS10960	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SCAB_RS10965	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SCAB_RS10995	COG1799	cell septum assembly
SCAB_RS11000	COG0243	molybdopterin cofactor binding
SCAB_RS11025	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SCAB_RS11030	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SCAB_RS11085	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SCAB_RS11100	COG4310	Domain of unknown function (DUF2172)
SCAB_RS11110	COG1215	transferase activity, transferring glycosyl groups
SCAB_RS11125	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SCAB_RS11135	COG0583	DNA-binding transcription factor activity
SCAB_RS11155	COG1090	epimerase
SCAB_RS11170	COG3485	protocatechuate 3,4-dioxygenase
SCAB_RS11175	COG1454	alcohol dehydrogenase
SCAB_RS11185	COG1960	acyl-CoA dehydrogenase activity
SCAB_RS11220	COG0492	ferredoxin-NADP+ reductase activity
SCAB_RS11225	COG0640	Transcriptional regulator
SCAB_RS11255	COG2072	flavoprotein involved in K transport
SCAB_RS11270	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SCAB_RS11275	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SCAB_RS11280	COG0492	ferredoxin-NADP+ reductase activity
SCAB_RS11285	COG3118	belongs to the thioredoxin family
SCAB_RS11310	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SCAB_RS11315	COG0531	amino acid
SCAB_RS11320	COG0569	domain protein
SCAB_RS11355	COG0756	dUTP diphosphatase activity
SCAB_RS11380	COG2205	protein histidine kinase activity
SCAB_RS11385	COG0745	RESPONSE REGULATOR receiver
SCAB_RS11395	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SCAB_RS11425	COG1435	thymidine kinase activity
SCAB_RS11440	COG1042	CoA-binding domain protein
SCAB_RS11440	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SCAB_RS11440	COG0045	succinate-CoA ligase (ADP-forming) activity
SCAB_RS11445	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SCAB_RS11450	COG1802	Transcriptional regulator
SCAB_RS11465	COG0612	Peptidase, M16
SCAB_RS11470	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SCAB_RS11495	COG3290	protein histidine kinase activity
SCAB_RS11500	COG4565	transcriptional regulatory protein
SCAB_RS11505	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SCAB_RS11515	COG0187	DNA topoisomerase II activity
SCAB_RS11535	COG3293	Transposase
SCAB_RS11540	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SCAB_RS11545	COG2186	Transcriptional regulator
SCAB_RS11550	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
SCAB_RS11570	COG0514	ATP-dependent DNA helicase (RecQ)
SCAB_RS11585	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SCAB_RS11610	COG0588	phosphoglycerate mutase activity
SCAB_RS11625	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SCAB_RS11630	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SCAB_RS11635	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SCAB_RS11665	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SCAB_RS11675	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SCAB_RS11680	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SCAB_RS11690	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SCAB_RS11710	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SCAB_RS11725	COG2205	protein histidine kinase activity
SCAB_RS11730	COG0745	RESPONSE REGULATOR receiver
SCAB_RS11735	COG1126	abc transporter atp-binding protein
SCAB_RS11740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SCAB_RS11745	COG0765	amino acid transport
SCAB_RS11750	COG0765	amino acid transport
SCAB_RS11755	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SCAB_RS11770	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SCAB_RS11775	COG0628	permease
SCAB_RS11800	COG2207	Transcriptional regulator
SCAB_RS11805	COG1201	RNA secondary structure unwinding
SCAB_RS11810	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SCAB_RS11815	COG1028	Short-chain dehydrogenase reductase Sdr
SCAB_RS11820	COG0783	Belongs to the Dps family
SCAB_RS11825	COG1396	sequence-specific DNA binding
SCAB_RS11830	COG1058	Belongs to the CinA family
SCAB_RS11830	COG1546	Belongs to the CinA family
SCAB_RS11840	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SCAB_RS11850	COG1674	ftsk spoiiie
SCAB_RS11860	COG2205	protein histidine kinase activity
SCAB_RS11860	COG3437	response regulator, receiver
SCAB_RS11860	COG3850	Histidine kinase
SCAB_RS11860	COG4999	Histidine kinase
SCAB_RS11865	COG2208	phosphoserine phosphatase activity
SCAB_RS11865	COG2770	Histidine kinase
SCAB_RS11895	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SCAB_RS11900	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SCAB_RS11905	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
SCAB_RS11920	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SCAB_RS11925	COG0612	Peptidase, M16
SCAB_RS11930	COG1185	polyribonucleotide nucleotidyltransferase activity
SCAB_RS11935	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
SCAB_RS11945	COG0455	bacterial-type flagellum organization
SCAB_RS11960	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SCAB_RS11965	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SCAB_RS11975	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SCAB_RS11995	COG0779	Required for maturation of 30S ribosomal subunits
SCAB_RS12015	COG0442	prolyl-tRNA aminoacylation
SCAB_RS12030	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SCAB_RS12035	COG0750	zinc metalloprotease
SCAB_RS12040	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
SCAB_RS12065	COG0628	permease
SCAB_RS12080	COG1609	Transcriptional regulator
SCAB_RS12100	COG0395	ABC-type sugar transport system, permease component
SCAB_RS12105	COG4209	transmembrane transport
SCAB_RS12110	COG1653	transport
SCAB_RS12115	COG1472	Belongs to the glycosyl hydrolase 3 family
SCAB_RS12120	COG1012	belongs to the aldehyde dehydrogenase family
SCAB_RS12125	COG2508	Transcriptional regulator
SCAB_RS12150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SCAB_RS12155	COG1177	transmembrane transport
SCAB_RS12165	COG3842	ATPase activity
SCAB_RS12190	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SCAB_RS12205	COG2353	YceI-like domain
SCAB_RS12210	COG1012	belongs to the aldehyde dehydrogenase family
SCAB_RS12220	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SCAB_RS12225	COG1136	(ABC) transporter
SCAB_RS12250	COG3842	ATPase activity
SCAB_RS12255	COG4208	sulfate ABC transporter
SCAB_RS12265	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SCAB_RS12280	COG0575	Belongs to the CDS family
SCAB_RS12285	COG0233	cytoplasmic translational termination
SCAB_RS12290	COG0528	UMP kinase activity
SCAB_RS12295	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SCAB_RS12300	COG0052	Belongs to the universal ribosomal protein uS2 family
SCAB_RS12305	COG4942	peptidase
SCAB_RS12315	COG1191	sigma factor activity
SCAB_RS12330	COG0792	nuclease activity
SCAB_RS12340	COG0494	nUDIX hydrolase
SCAB_RS12345	COG0681	Belongs to the peptidase S26 family
SCAB_RS12350	COG0681	Belongs to the peptidase S26 family
SCAB_RS12365	COG0335	large ribosomal subunit rRNA binding
SCAB_RS12370	COG0336	Belongs to the RNA methyltransferase TrmD family
SCAB_RS12375	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SCAB_RS12380	COG1837	Belongs to the UPF0109 family
SCAB_RS12385	COG0228	four-way junction DNA binding
SCAB_RS12395	COG0442	prolyl-tRNA aminoacylation
SCAB_RS12410	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
SCAB_RS12450	COG0477	Major facilitator Superfamily
SCAB_RS12455	COG1196	nuclear chromosome segregation
SCAB_RS12465	COG1254	Belongs to the acylphosphatase family
SCAB_RS12470	COG2340	Cysteine-rich secretory protein family
SCAB_RS12475	COG1733	regulation of RNA biosynthetic process
SCAB_RS12480	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SCAB_RS12485	COG0571	ribonuclease III activity
SCAB_RS12490	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SCAB_RS12505	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SCAB_RS12510	COG0742	ribosomal rna small subunit methyltransferase
SCAB_RS12520	COG0326	Molecular chaperone. Has ATPase activity
SCAB_RS12530	COG1461	Dihydroxyacetone kinase
SCAB_RS12535	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SCAB_RS12540	COG0351	phosphomethylpyrimidine kinase
SCAB_RS12560	COG1181	Belongs to the D-alanine--D-alanine ligase family
SCAB_RS12565	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SCAB_RS12575	COG1920	GTP binding
SCAB_RS12585	COG0776	regulation of translation
SCAB_RS12595	COG0066	3-isopropylmalate dehydratase activity
SCAB_RS12600	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SCAB_RS12605	COG1414	Transcriptional regulator
SCAB_RS12650	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SCAB_RS12655	COG0179	Fumarylacetoacetate (FAA) hydrolase
SCAB_RS12665	COG5002	protein histidine kinase activity
SCAB_RS12670	COG2018	Roadblock/LC7 domain
SCAB_RS12690	COG2018	Roadblock/LC7 domain
SCAB_RS12710	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SCAB_RS12750	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SCAB_RS12755	COG1309	transcriptional regulator
SCAB_RS12760	COG2957	Belongs to the agmatine deiminase family
SCAB_RS12765	COG0804	urea catabolic process
SCAB_RS12770	COG0831	urea catabolic process
SCAB_RS12770	COG0832	Belongs to the urease beta subunit family
SCAB_RS12780	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SCAB_RS12785	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SCAB_RS12790	COG0473	3-isopropylmalate dehydrogenase activity
SCAB_RS12800	COG1012	belongs to the aldehyde dehydrogenase family
SCAB_RS12805	COG0506	proline dehydrogenase activity
SCAB_RS12815	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SCAB_RS12815	COG0515	serine threonine protein kinase
SCAB_RS12820	COG2197	response regulator
SCAB_RS12825	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SCAB_RS12830	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SCAB_RS12835	COG0440	acetolactate synthase activity
SCAB_RS12845	COG5001	Diguanylate cyclase
SCAB_RS12855	COG0667	Aldo Keto reductase
SCAB_RS12870	COG2197	response regulator
SCAB_RS12885	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SCAB_RS12890	COG2409	Drug exporters of the RND superfamily
SCAB_RS12895	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SCAB_RS12905	COG0154	amidase activity
SCAB_RS12910	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SCAB_RS12920	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SCAB_RS12930	COG4221	oxidoreductase activity
SCAB_RS12945	COG0482	sulfurtransferase activity
SCAB_RS12950	COG3023	N-Acetylmuramoyl-L-alanine amidase
SCAB_RS12970	COG1309	transcriptional regulator
SCAB_RS12980	COG2860	membrane
SCAB_RS12985	COG4608	Belongs to the ABC transporter superfamily
SCAB_RS12990	COG0444	Belongs to the ABC transporter superfamily
SCAB_RS13000	COG0747	negative chemotaxis
SCAB_RS13005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SCAB_RS13025	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SCAB_RS13030	COG0509	glycine decarboxylation via glycine cleavage system
SCAB_RS13035	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SCAB_RS13040	COG1760	l-serine dehydratase
SCAB_RS13070	COG0464	growth
SCAB_RS13145	COG3409	Peptidoglycan-binding domain 1 protein
SCAB_RS13145	COG3757	hydrolase, family 25
SCAB_RS13150	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SCAB_RS13185	COG1376	ErfK ybiS ycfS ynhG family protein
SCAB_RS13200	COG2197	response regulator
SCAB_RS13205	COG4585	Histidine kinase
SCAB_RS13215	COG1131	(ABC) transporter
SCAB_RS13220	COG1132	(ABC) transporter
SCAB_RS13225	COG1132	(ABC) transporter
SCAB_RS13230	COG1132	(ABC) transporter
SCAB_RS13235	COG1132	(ABC) transporter
SCAB_RS13255	COG0058	SHG alpha-glucan phosphorylase activity
SCAB_RS13265	COG0366	Alpha amylase catalytic
SCAB_RS13270	COG0366	Alpha amylase catalytic
SCAB_RS13275	COG3281	Trehalose synthase
SCAB_RS13280	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SCAB_RS13295	COG0492	ferredoxin-NADP+ reductase activity
SCAB_RS13295	COG3118	belongs to the thioredoxin family
SCAB_RS13300	COG0789	Transcriptional regulator
SCAB_RS13305	COG1301	dicarboxylic acid transport
SCAB_RS13310	COG3290	protein histidine kinase activity
SCAB_RS13315	COG4565	transcriptional regulatory protein
SCAB_RS13325	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SCAB_RS13330	COG3629	intracellular signal transduction
SCAB_RS13330	COG3903	Transcriptional regulator
SCAB_RS13340	COG1175	transmembrane transport
SCAB_RS13345	COG0395	ABC-type sugar transport system, permease component
SCAB_RS13355	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SCAB_RS13375	COG0205	6-phosphofructokinase activity
SCAB_RS13380	COG0280	phosphate acetyltransferase
SCAB_RS13380	COG0857	belongs to the CobB CobQ family
SCAB_RS13385	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SCAB_RS13420	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SCAB_RS13420	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SCAB_RS13485	COG0642	Histidine kinase
SCAB_RS13490	COG0745	RESPONSE REGULATOR receiver
SCAB_RS13510	COG0183	Belongs to the thiolase family
SCAB_RS13530	COG1131	(ABC) transporter
SCAB_RS13565	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
SCAB_RS13580	COG1250	3-hydroxyacyl-CoA dehydrogenase
SCAB_RS13585	COG1309	transcriptional regulator
SCAB_RS13615	COG4585	Histidine kinase
SCAB_RS13620	COG2197	response regulator
SCAB_RS13635	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SCAB_RS13640	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SCAB_RS13645	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SCAB_RS13650	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SCAB_RS13655	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SCAB_RS13660	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SCAB_RS13665	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SCAB_RS13685	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SCAB_RS13690	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SCAB_RS13700	COG2890	protein-(glutamine-N5) methyltransferase activity
SCAB_RS13705	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SCAB_RS13710	COG0254	rRNA binding
SCAB_RS13730	COG0083	homoserine kinase activity
SCAB_RS13735	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SCAB_RS13740	COG0460	homoserine dehydrogenase
SCAB_RS13745	COG0019	diaminopimelate decarboxylase activity
SCAB_RS13750	COG0018	arginyl-trna synthetase
SCAB_RS13755	COG0745	RESPONSE REGULATOR receiver
SCAB_RS13845	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SCAB_RS13860	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
SCAB_RS13990	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
SCAB_RS13995	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SCAB_RS14000	COG3285	dna ligase
SCAB_RS14000	COG1793	dna ligase
SCAB_RS14020	COG2205	protein histidine kinase activity
SCAB_RS14035	COG0768	penicillin binding
SCAB_RS14105	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SCAB_RS14120	COG0745	RESPONSE REGULATOR receiver
SCAB_RS14125	COG2205	protein histidine kinase activity
SCAB_RS14130	COG0508	dehydrogenase complex catalyzes the overall conversion of
SCAB_RS14130	COG0567	Dehydrogenase, E1 component
SCAB_RS14165	COG0604	alcohol dehydrogenase
SCAB_RS14175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SCAB_RS14185	COG1126	abc transporter atp-binding protein
SCAB_RS14215	COG1609	Transcriptional regulator
SCAB_RS14225	COG1175	transmembrane transport
SCAB_RS14230	COG0395	ABC-type sugar transport system, permease component
SCAB_RS14235	COG4977	sequence-specific DNA binding
SCAB_RS14255	COG0142	geranyltranstransferase activity
SCAB_RS14260	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SCAB_RS14300	COG1597	lipid kinase activity
SCAB_RS14315	COG0363	glucosamine-6-phosphate deaminase activity
SCAB_RS14320	COG1472	Belongs to the glycosyl hydrolase 3 family
SCAB_RS14325	COG0395	ABC-type sugar transport system, permease component
SCAB_RS14330	COG1175	transmembrane transport
SCAB_RS14335	COG2182	Extracellular solute-binding protein
SCAB_RS14340	COG2188	Transcriptional regulator
SCAB_RS14355	COG1957	nucleoside hydrolase
SCAB_RS14380	COG0242	peptide deformylase activity
SCAB_RS14415	COG5662	AntiSigma factor
SCAB_RS14420	COG1595	DNA-templated transcription, initiation
SCAB_RS14430	COG2135	peptidase activity
SCAB_RS14440	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SCAB_RS14460	COG0483	inositol monophosphate 1-phosphatase activity
SCAB_RS14490	COG1615	UPF0182 protein
SCAB_RS14500	COG3480	Lon protease (S16) C-terminal proteolytic domain
SCAB_RS14510	COG3293	Transposase
SCAB_RS14565	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SCAB_RS14610	COG0210	DNA helicase
SCAB_RS14635	COG0596	Alpha beta hydrolase
SCAB_RS14640	COG3293	Transposase
SCAB_RS14720	COG1432	Conserved Protein
SCAB_RS14725	COG2095	MarC family integral membrane protein
SCAB_RS14745	COG0598	Magnesium transport protein CorA
SCAB_RS14780	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SCAB_RS14785	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SCAB_RS14795	COG1595	DNA-templated transcription, initiation
SCAB_RS14805	COG1024	Enoyl-CoA hydratase
SCAB_RS14810	COG2818	Glycosylase
SCAB_RS14820	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SCAB_RS14830	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SCAB_RS14865	COG2197	response regulator
SCAB_RS14870	COG4585	Histidine kinase
SCAB_RS14880	COG1131	(ABC) transporter
SCAB_RS14895	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SCAB_RS14910	COG4608	Belongs to the ABC transporter superfamily
SCAB_RS14915	COG0444	Belongs to the ABC transporter superfamily
SCAB_RS14920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SCAB_RS14925	COG0601	transmembrane transport
SCAB_RS14935	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SCAB_RS14940	COG4166	transmembrane transport
SCAB_RS14955	COG4608	Belongs to the ABC transporter superfamily
SCAB_RS14960	COG0444	Belongs to the ABC transporter superfamily
SCAB_RS14965	COG0601	transmembrane transport
SCAB_RS14970	COG0747	negative chemotaxis
SCAB_RS14975	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SCAB_RS14980	COG1217	gtp-binding protein TYPA
SCAB_RS15005	COG1053	succinate dehydrogenase
SCAB_RS15010	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SCAB_RS15050	COG0133	tryptophan synthase activity
SCAB_RS15080	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SCAB_RS15100	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
SCAB_RS15115	COG0582	viral genome integration into host DNA
SCAB_RS15135	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SCAB_RS15170	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SCAB_RS15405	COG1793	dna ligase
SCAB_RS15445	COG0151	Belongs to the GarS family
SCAB_RS15630	COG0714	Associated with various cellular activities
SCAB_RS15745	COG2801	Transposase and inactivated derivatives
SCAB_RS15750	COG3547	Transposase (IS116 IS110 IS902 family)
SCAB_RS15770	COG0519	Catalyzes the synthesis of GMP from XMP
SCAB_RS15790	COG1061	Type III restriction enzyme res subunit
SCAB_RS15835	COG0012	GTP binding
SCAB_RS15850	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
SCAB_RS15855	COG1570	exodeoxyribonuclease VII activity
SCAB_RS15860	COG1722	exodeoxyribonuclease VII activity
SCAB_RS15865	COG0778	Nitroreductase
SCAB_RS15890	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
SCAB_RS15890	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
SCAB_RS15900	COG0114	fumarate hydratase activity
SCAB_RS15915	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SCAB_RS15925	COG1136	(ABC) transporter
SCAB_RS15935	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SCAB_RS15950	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SCAB_RS15955	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
SCAB_RS15975	COG2885	chlorophyll binding
SCAB_RS16000	COG3851	Histidine kinase
SCAB_RS16080	COG0251	oxidation-reduction process
SCAB_RS16085	COG1414	Transcriptional regulator
SCAB_RS16100	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
SCAB_RS16170	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
SCAB_RS16190	COG1309	transcriptional regulator
SCAB_RS16205	COG2132	Multicopper oxidase
SCAB_RS16210	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SCAB_RS16215	COG1846	Transcriptional regulator
SCAB_RS16240	COG1331	Highly conserved protein containing a thioredoxin domain
SCAB_RS16265	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SCAB_RS16275	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SCAB_RS16280	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SCAB_RS16285	COG2255	four-way junction helicase activity
SCAB_RS16310	COG0501	Belongs to the peptidase M48B family
SCAB_RS16320	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SCAB_RS16325	COG1064	alcohol dehydrogenase
SCAB_RS16335	COG1404	Belongs to the peptidase S8 family
SCAB_RS16340	COG1136	(ABC) transporter
SCAB_RS16365	COG2986	histidine ammonia-lyase
SCAB_RS16375	COG1024	Enoyl-CoA hydratase
SCAB_RS16385	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SCAB_RS16395	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SCAB_RS16405	COG0424	maF-like protein
SCAB_RS16415	COG4770	biotin carboxylase activity
SCAB_RS16445	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SCAB_RS16460	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
SCAB_RS16465	COG1012	belongs to the aldehyde dehydrogenase family
SCAB_RS16470	COG1012	belongs to the aldehyde dehydrogenase family
SCAB_RS16485	COG1595	DNA-templated transcription, initiation
SCAB_RS16490	COG0745	RESPONSE REGULATOR receiver
SCAB_RS16495	COG2205	protein histidine kinase activity
SCAB_RS16520	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SCAB_RS16530	COG0583	DNA-binding transcription factor activity
SCAB_RS16535	COG2814	Major facilitator Superfamily
SCAB_RS16555	COG1079	Belongs to the binding-protein-dependent transport system permease family
SCAB_RS16560	COG4603	Belongs to the binding-protein-dependent transport system permease family
SCAB_RS16565	COG3845	ABC transporter
SCAB_RS16570	COG1744	ABC transporter substrate-binding protein PnrA-like
SCAB_RS16575	COG1744	ABC transporter substrate-binding protein PnrA-like
SCAB_RS16580	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SCAB_RS16580	COG1473	amidohydrolase
SCAB_RS16595	COG2089	acid synthase
SCAB_RS16610	COG1216	Glycosyl transferase, family 2
SCAB_RS16620	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SCAB_RS16655	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SCAB_RS16655	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SCAB_RS16670	COG1595	DNA-templated transcription, initiation
SCAB_RS16680	COG1595	DNA-templated transcription, initiation
SCAB_RS16715	COG2009	succinate dehydrogenase
SCAB_RS16725	COG1053	succinate dehydrogenase
SCAB_RS16780	COG4974	Belongs to the 'phage' integrase family
SCAB_RS16810	COG1309	transcriptional regulator
SCAB_RS16825	COG1408	metallophosphoesterase
SCAB_RS16835	COG1686	Belongs to the peptidase S11 family
SCAB_RS16870	COG0180	Tryptophanyl-tRNA synthetase
SCAB_RS16875	COG1595	DNA-templated transcription, initiation
SCAB_RS16890	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SCAB_RS16895	COG0754	glutathionylspermidine amidase activity
SCAB_RS16910	COG0039	L-malate dehydrogenase activity
SCAB_RS16925	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SCAB_RS16940	COG0138	bifunctional purine biosynthesis protein purh
SCAB_RS16970	COG0045	succinate-CoA ligase (ADP-forming) activity
SCAB_RS16980	COG3552	Protein containing von Willebrand factor type A (VWA) domain
SCAB_RS16990	COG0714	Associated with various cellular activities
SCAB_RS17005	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SCAB_RS17005	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SCAB_RS17015	COG0739	heme binding
SCAB_RS17035	COG0791	NLP P60 protein
SCAB_RS17040	COG2197	response regulator
SCAB_RS17075	COG0519	Catalyzes the synthesis of GMP from XMP
SCAB_RS17075	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SCAB_RS17095	COG1012	belongs to the aldehyde dehydrogenase family
SCAB_RS17110	COG0515	serine threonine protein kinase
SCAB_RS17120	COG0515	serine threonine protein kinase
SCAB_RS17135	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SCAB_RS17145	COG0516	GMP reductase activity
SCAB_RS17155	COG1595	DNA-templated transcription, initiation
SCAB_RS17170	COG0583	DNA-binding transcription factor activity
SCAB_RS17180	COG4221	oxidoreductase activity
SCAB_RS17190	COG0459	protein refolding
SCAB_RS17195	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SCAB_RS17200	COG0726	polysaccharide deacetylase
SCAB_RS17205	COG0726	polysaccharide deacetylase
SCAB_RS17215	COG4941	Belongs to the sigma-70 factor family
SCAB_RS17225	COG1316	TRANSCRIPTIONal
SCAB_RS17240	COG1653	transport
SCAB_RS17245	COG1175	transmembrane transport
SCAB_RS17255	COG1472	Belongs to the glycosyl hydrolase 3 family
SCAB_RS17280	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SCAB_RS17300	COG0802	atpase or kinase
SCAB_RS17305	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SCAB_RS17310	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SCAB_RS17320	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SCAB_RS17325	COG0736	holo-[acyl-carrier-protein] synthase activity
SCAB_RS17340	COG1072	(Pantothenic acid kinase))
SCAB_RS17350	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SCAB_RS17355	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SCAB_RS17360	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SCAB_RS17370	COG0101	tRNA pseudouridine synthase activity
SCAB_RS17375	COG0203	ribosomal protein L17
SCAB_RS17380	COG0202	RNA polymerase activity
SCAB_RS17385	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SCAB_RS17390	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SCAB_RS17395	COG0257	Belongs to the bacterial ribosomal protein bL36 family
SCAB_RS17400	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SCAB_RS17410	COG0563	adenylate kinase activity
SCAB_RS17420	COG0200	Binds to the 23S rRNA
SCAB_RS17425	COG1841	ribosomal large subunit assembly
SCAB_RS17430	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SCAB_RS17435	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SCAB_RS17440	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SCAB_RS17445	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SCAB_RS17450	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SCAB_RS17455	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SCAB_RS17460	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SCAB_RS17465	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SCAB_RS17470	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SCAB_RS17475	COG0255	Belongs to the universal ribosomal protein uL29 family
SCAB_RS17480	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SCAB_RS17485	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SCAB_RS17490	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SCAB_RS17495	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SCAB_RS17500	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SCAB_RS17510	COG0088	Forms part of the polypeptide exit tunnel
SCAB_RS17515	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SCAB_RS17520	COG0051	transcription antitermination factor activity, RNA binding
SCAB_RS17585	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SCAB_RS17590	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SCAB_RS17595	COG0049	tRNA binding
SCAB_RS17600	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SCAB_RS17630	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SCAB_RS17635	COG0085	RNA polymerase activity
SCAB_RS17640	COG0222	ribosome binding
SCAB_RS17645	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SCAB_RS17655	COG0081	regulation of translation
SCAB_RS17660	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SCAB_RS17680	COG0436	Aminotransferase
SCAB_RS17685	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SCAB_RS17690	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SCAB_RS17700	COG2030	dehydratase
SCAB_RS17705	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SCAB_RS17720	COG0402	S-adenosylhomocysteine deaminase activity
SCAB_RS17730	COG0702	epimerase
SCAB_RS17745	COG1666	GTP binding
SCAB_RS17760	COG3304	Inner membrane component domain
SCAB_RS17765	COG0501	Belongs to the peptidase M48B family
SCAB_RS17770	COG1007	ATP synthesis coupled electron transport
SCAB_RS17785	COG0713	ATP synthesis coupled electron transport
SCAB_RS17790	COG0839	Belongs to the complex I subunit 6 family
SCAB_RS17795	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SCAB_RS17800	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SCAB_RS17805	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SCAB_RS17810	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SCAB_RS17815	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SCAB_RS17835	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SCAB_RS17835	COG0674	pyruvate-flavodoxin oxidoreductase activity
SCAB_RS17840	COG1013	pyruvate-flavodoxin oxidoreductase activity
SCAB_RS17845	COG1733	regulation of RNA biosynthetic process
SCAB_RS17850	COG0702	epimerase
SCAB_RS17880	COG1196	nuclear chromosome segregation
SCAB_RS17880	COG0741	lytic transglycosylase activity
SCAB_RS17880	COG0739	heme binding
SCAB_RS17930	COG0655	NAD(P)H dehydrogenase (quinone) activity
SCAB_RS17940	COG1131	(ABC) transporter
SCAB_RS17950	COG0142	geranyltranstransferase activity
SCAB_RS17960	COG0561	phosphatase activity
SCAB_RS17970	COG2188	Transcriptional regulator
SCAB_RS17995	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SCAB_RS18005	COG0514	ATP-dependent DNA helicase (RecQ)
SCAB_RS18010	COG1007	ATP synthesis coupled electron transport
SCAB_RS18020	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SCAB_RS18025	COG0713	ATP synthesis coupled electron transport
SCAB_RS18030	COG0839	Belongs to the complex I subunit 6 family
SCAB_RS18035	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SCAB_RS18040	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SCAB_RS18045	COG1034	ATP synthesis coupled electron transport
SCAB_RS18050	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SCAB_RS18060	COG0649	NAD binding
SCAB_RS18065	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SCAB_RS18070	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SCAB_RS18105	COG2226	methyltransferase
SCAB_RS18120	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SCAB_RS18135	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
SCAB_RS18140	COG1278	Cold shock
SCAB_RS18180	COG1309	transcriptional regulator
SCAB_RS18195	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SCAB_RS18205	COG0163	prenyltransferase activity
SCAB_RS18225	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
SCAB_RS18235	COG0789	Transcriptional regulator
SCAB_RS18300	COG1725	Transcriptional regulator
SCAB_RS18340	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SCAB_RS18345	COG1333	cytochrome c biogenesis protein
SCAB_RS18355	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SCAB_RS18370	COG0406	alpha-ribazole phosphatase activity
SCAB_RS18375	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SCAB_RS18400	COG0436	Aminotransferase
SCAB_RS18435	COG0438	transferase activity, transferring glycosyl groups
SCAB_RS18445	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SCAB_RS18465	COG1690	Belongs to the RtcB family
SCAB_RS18490	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
SCAB_RS18495	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
SCAB_RS18500	COG0018	arginyl-trna synthetase
SCAB_RS18510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SCAB_RS18535	COG0113	porphobilinogen synthase activity
SCAB_RS18550	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SCAB_RS18550	COG1648	precorrin-2 dehydrogenase activity
SCAB_RS18555	COG0181	hydroxymethylbilane synthase activity
SCAB_RS18560	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
SCAB_RS18565	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
SCAB_RS18615	COG0738	Major facilitator superfamily
SCAB_RS18620	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SCAB_RS18640	COG0180	Tryptophanyl-tRNA synthetase
SCAB_RS18645	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SCAB_RS18655	COG1129	ABC transporter
SCAB_RS18655	COG0842	Transport permease protein
SCAB_RS18670	COG4991	sh3 domain protein
SCAB_RS18675	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SCAB_RS18675	COG0515	serine threonine protein kinase
SCAB_RS18680	COG0129	dihydroxy-acid dehydratase activity
SCAB_RS18685	COG1309	transcriptional regulator
SCAB_RS18690	COG1082	Xylose isomerase domain protein TIM barrel
SCAB_RS18695	COG0248	Ppx GppA phosphatase
SCAB_RS18720	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
SCAB_RS18735	COG1194	a g-specific adenine glycosylase
SCAB_RS18740	COG1595	DNA-templated transcription, initiation
SCAB_RS18750	COG0745	RESPONSE REGULATOR receiver
SCAB_RS18755	COG2205	protein histidine kinase activity
SCAB_RS18775	COG0739	heme binding
SCAB_RS18785	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SCAB_RS18795	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
SCAB_RS18815	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
SCAB_RS18825	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SCAB_RS18830	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
SCAB_RS18860	COG0649	NAD binding
SCAB_RS18900	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
SCAB_RS18905	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SCAB_RS18915	COG0302	gtp cyclohydrolase
SCAB_RS18930	COG0037	tRNA processing
SCAB_RS18945	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SCAB_RS18955	COG0586	Pfam SNARE associated Golgi protein
SCAB_RS18960	COG0789	Transcriptional regulator
SCAB_RS18970	COG0076	glutamate decarboxylase activity
SCAB_RS18990	COG2318	DinB family
SCAB_RS18995	COG1012	belongs to the aldehyde dehydrogenase family
SCAB_RS19015	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SCAB_RS19025	COG0254	rRNA binding
SCAB_RS19030	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SCAB_RS19035	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SCAB_RS19040	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SCAB_RS19060	COG1136	(ABC) transporter
SCAB_RS19075	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SCAB_RS19075	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SCAB_RS19095	COG2197	response regulator
SCAB_RS19100	COG4585	Histidine kinase
SCAB_RS19105	COG0577	efflux transmembrane transporter activity
SCAB_RS19105	COG1136	(ABC) transporter
SCAB_RS19115	COG2197	response regulator
SCAB_RS19130	COG1653	transport
SCAB_RS19145	COG0515	serine threonine protein kinase
SCAB_RS19170	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SCAB_RS19190	COG0592	DNA-directed DNA polymerase activity
SCAB_RS19295	COG2226	methyltransferase
SCAB_RS19300	COG0215	cysteine-tRNA ligase activity
SCAB_RS19310	COG0489	protein tyrosine kinase activity
SCAB_RS19320	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SCAB_RS19325	COG0017	Asparaginyl-tRNA synthetase
SCAB_RS19360	COG1487	ribonuclease activity
SCAB_RS19365	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
SCAB_RS19395	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SCAB_RS19400	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SCAB_RS19405	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SCAB_RS19405	COG1754	DNA topoisomerase type I activity
SCAB_RS19430	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
SCAB_RS19435	COG2172	sigma factor antagonist activity
SCAB_RS19440	COG1366	Belongs to the anti-sigma-factor antagonist family
SCAB_RS19445	COG1205	dead DEAH box helicase
SCAB_RS19445	COG1111	helicase
SCAB_RS19505	COG1396	sequence-specific DNA binding
SCAB_RS19600	COG0288	reversible hydration of carbon dioxide
SCAB_RS19605	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SCAB_RS19610	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SCAB_RS19620	COG0596	Alpha beta hydrolase
SCAB_RS19655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SCAB_RS19665	COG0251	oxidation-reduction process
SCAB_RS19675	COG0003	Pfam Anion-transporting ATPase
SCAB_RS19695	COG1408	metallophosphoesterase
SCAB_RS19710	COG1247	-acetyltransferase
SCAB_RS19715	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SCAB_RS19725	COG0640	Transcriptional regulator
SCAB_RS19750	COG0701	Predicted permease
SCAB_RS19760	COG0523	cobalamin synthesis protein
SCAB_RS19800	COG1595	DNA-templated transcription, initiation
SCAB_RS19825	COG5002	protein histidine kinase activity
SCAB_RS19835	COG3629	intracellular signal transduction
SCAB_RS19835	COG3903	Transcriptional regulator
SCAB_RS19865	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SCAB_RS19875	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SCAB_RS19880	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SCAB_RS19900	COG0693	protein deglycase activity
SCAB_RS19910	COG1802	Transcriptional regulator
SCAB_RS19930	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SCAB_RS19990	COG1131	(ABC) transporter
SCAB_RS19995	COG3559	Exporter of polyketide antibiotics
SCAB_RS20005	COG2124	cytochrome p450
SCAB_RS20010	COG2197	response regulator
SCAB_RS20015	COG4585	Histidine kinase
SCAB_RS20020	COG2197	response regulator
SCAB_RS20025	COG4585	Histidine kinase
SCAB_RS20045	COG3844	kynureninase activity
SCAB_RS20050	COG3483	tryptophan 2,3-dioxygenase activity
SCAB_RS20060	COG0477	Major facilitator Superfamily
SCAB_RS20065	COG0191	fructose-bisphosphate aldolase activity
SCAB_RS20070	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SCAB_RS20085	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
SCAB_RS20100	COG2409	Drug exporters of the RND superfamily
SCAB_RS20110	COG0745	RESPONSE REGULATOR receiver
SCAB_RS20130	COG0542	response to heat
SCAB_RS20170	COG1305	Transglutaminase-like
SCAB_RS20175	COG4213	ABC transporter substrate-binding protein
SCAB_RS20240	COG0789	Transcriptional regulator
SCAB_RS20245	COG0484	heat shock protein binding
SCAB_RS20250	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SCAB_RS20255	COG0443	Heat shock 70 kDa protein
SCAB_RS20260	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SCAB_RS20265	COG0247	lactate metabolic process
SCAB_RS20265	COG2181	nitrate reductase activity
SCAB_RS20325	COG0717	Belongs to the dCTP deaminase family
SCAB_RS20335	COG1028	Short-chain dehydrogenase reductase Sdr
SCAB_RS20340	COG0604	alcohol dehydrogenase
SCAB_RS20340	COG3321	synthase
SCAB_RS20365	COG2255	four-way junction helicase activity
SCAB_RS20460	COG0725	ABC transporter, periplasmic molybdate-binding protein
SCAB_RS20530	COG4213	ABC transporter substrate-binding protein
SCAB_RS20545	COG0726	polysaccharide deacetylase
SCAB_RS20550	COG4213	ABC transporter substrate-binding protein
SCAB_RS20560	COG4214	carbohydrate transport
SCAB_RS20565	COG1309	transcriptional regulator
SCAB_RS20575	COG2072	flavoprotein involved in K transport
SCAB_RS20595	COG0662	Cupin 2, conserved barrel domain protein
SCAB_RS20610	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SCAB_RS20635	COG1295	ribonuclease BN
SCAB_RS20650	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
SCAB_RS20655	COG0531	amino acid
SCAB_RS20670	COG1278	Cold shock
SCAB_RS20675	COG0513	Belongs to the DEAD box helicase family
SCAB_RS20690	COG2764	glyoxalase bleomycin resistance protein dioxygenase
SCAB_RS20695	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SCAB_RS20700	COG3250	beta-galactosidase activity
SCAB_RS20710	COG3973	AAA domain
SCAB_RS20765	COG1609	Transcriptional regulator
SCAB_RS20775	COG4585	Histidine kinase
SCAB_RS20795	COG2197	response regulator
SCAB_RS20800	COG4585	Histidine kinase
SCAB_RS20805	COG2409	Drug exporters of the RND superfamily
SCAB_RS20810	COG1733	regulation of RNA biosynthetic process
SCAB_RS20840	COG1846	Transcriptional regulator
SCAB_RS20855	COG2188	Transcriptional regulator
SCAB_RS20865	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SCAB_RS20980	COG0137	argininosuccinate synthase activity
SCAB_RS21055	COG1733	regulation of RNA biosynthetic process
SCAB_RS21060	COG3345	alpha-galactosidase
SCAB_RS21175	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SCAB_RS21205	COG1595	DNA-templated transcription, initiation
SCAB_RS21225	COG1595	DNA-templated transcription, initiation
SCAB_RS21240	COG0745	RESPONSE REGULATOR receiver
SCAB_RS21245	COG2205	protein histidine kinase activity
SCAB_RS21275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SCAB_RS21280	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SCAB_RS21295	COG1289	transmembrane transporter activity
SCAB_RS21315	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SCAB_RS21345	COG3866	Pectate lyase
SCAB_RS21355	COG2340	Cysteine-rich secretory protein family
SCAB_RS21390	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SCAB_RS21405	COG0628	permease
SCAB_RS21415	COG1741	Belongs to the pirin family
SCAB_RS21425	COG1960	acyl-CoA dehydrogenase activity
SCAB_RS21430	COG1362	aminopeptidase activity
SCAB_RS21460	COG1802	Transcriptional regulator
SCAB_RS21475	COG0508	dehydrogenase complex catalyzes the overall conversion of
SCAB_RS21480	COG0022	dehydrogenase e1 component
SCAB_RS21490	COG0515	serine threonine protein kinase
SCAB_RS21495	COG0515	serine threonine protein kinase
SCAB_RS21530	COG0303	'Molybdopterin
SCAB_RS21535	COG0746	molybdenum cofactor guanylyltransferase activity
SCAB_RS21555	COG1522	sequence-specific DNA binding
SCAB_RS21560	COG1309	transcriptional regulator
SCAB_RS21565	COG1250	3-hydroxyacyl-CoA dehydrogenase
SCAB_RS21610	COG1733	regulation of RNA biosynthetic process
SCAB_RS21615	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
SCAB_RS21630	COG1716	ATPase activity
SCAB_RS21635	COG1716	ATPase activity
SCAB_RS21655	COG0515	serine threonine protein kinase
SCAB_RS21660	COG3764	Sortase (surface protein transpeptidase)
SCAB_RS21665	COG3764	Sortase (surface protein transpeptidase)
SCAB_RS21680	COG3764	Sortase (surface protein transpeptidase)
SCAB_RS21695	COG0705	Rhomboid family
SCAB_RS21720	COG0515	serine threonine protein kinase
SCAB_RS21745	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SCAB_RS21750	COG0187	DNA topoisomerase II activity
SCAB_RS21755	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
SCAB_RS21760	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SCAB_RS21765	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
SCAB_RS21770	COG0592	DNA-directed DNA polymerase activity
SCAB_RS21775	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SCAB_RS21785	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
SCAB_RS21790	COG0706	membrane insertase activity
SCAB_RS21800	COG0357	Ribosomal RNA small subunit methyltransferase G
SCAB_RS21805	COG1192	Involved in chromosome partitioning
SCAB_RS21820	COG3118	belongs to the thioredoxin family
SCAB_RS21825	COG0492	ferredoxin-NADP+ reductase activity
SCAB_RS21835	COG1595	DNA-templated transcription, initiation
SCAB_RS21840	COG2815	serine threonine protein kinase
SCAB_RS21840	COG0515	serine threonine protein kinase
SCAB_RS21855	COG0617	tRNA 3'-terminal CCA addition
SCAB_RS21865	COG1260	myo-inositol-1-phosphate synthase
SCAB_RS21875	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SCAB_RS21900	COG0360	Binds together with S18 to 16S ribosomal RNA
SCAB_RS21905	COG0629	single-stranded DNA binding
SCAB_RS21910	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SCAB_RS21915	COG0359	binds to the 23S rRNA
SCAB_RS21925	COG0305	Participates in initiation and elongation during chromosome replication
SCAB_RS21945	COG2814	Major facilitator Superfamily
SCAB_RS21970	COG0626	cystathionine gamma-synthase activity
SCAB_RS21975	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SCAB_RS21980	COG1950	PFAM Membrane protein of
SCAB_RS21985	COG0662	Cupin 2, conserved barrel domain protein
SCAB_RS22010	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
SCAB_RS22030	COG1609	Transcriptional regulator
SCAB_RS22035	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SCAB_RS22040	COG1271	oxidase subunit
SCAB_RS22045	COG1294	oxidase, subunit
SCAB_RS22050	COG4988	ABC transporter
SCAB_RS22055	COG0741	lytic transglycosylase activity
SCAB_RS22055	COG0739	heme binding
SCAB_RS22055	COG1196	nuclear chromosome segregation
SCAB_RS22060	COG0561	phosphatase activity
SCAB_RS22070	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
SCAB_RS22075	COG0789	Transcriptional regulator
SCAB_RS22090	COG1131	(ABC) transporter
SCAB_RS22120	COG0561	phosphatase activity
SCAB_RS22125	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SCAB_RS22135	COG2837	iron assimilation
SCAB_RS22150	COG1999	signal sequence binding
SCAB_RS22190	COG0641	radical SAM
SCAB_RS22205	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
SCAB_RS22210	COG0006	proline dipeptidase activity
SCAB_RS22230	COG0653	protein targeting
SCAB_RS22245	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SCAB_RS22260	COG2801	Transposase and inactivated derivatives
SCAB_RS22260	COG3415	Transposase
SCAB_RS22285	COG2188	Transcriptional regulator
SCAB_RS22350	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SCAB_RS22385	COG1595	DNA-templated transcription, initiation
SCAB_RS22390	COG0318	PFAM AMP-dependent synthetase and ligase
SCAB_RS22395	COG0784	Response regulator, receiver
SCAB_RS22415	COG0739	heme binding
SCAB_RS22430	COG2329	Antibiotic biosynthesis monooxygenase
SCAB_RS22435	COG0745	RESPONSE REGULATOR receiver
SCAB_RS22440	COG2205	protein histidine kinase activity
SCAB_RS22450	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SCAB_RS22455	COG0477	Major facilitator Superfamily
SCAB_RS22465	COG3467	pyridoxamine 5'-phosphate
SCAB_RS22470	COG2353	YceI-like domain
SCAB_RS22475	COG0477	Major facilitator Superfamily
SCAB_RS22490	COG1191	sigma factor activity
SCAB_RS22495	COG1191	sigma factor activity
SCAB_RS22530	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SCAB_RS22580	COG2372	response to copper ion
SCAB_RS22580	COG1276	copper resistance
SCAB_RS22645	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SCAB_RS22650	COG1454	alcohol dehydrogenase
SCAB_RS22675	COG0515	serine threonine protein kinase
SCAB_RS22705	COG0151	Belongs to the GarS family
SCAB_RS22720	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SCAB_RS22730	COG2197	response regulator
SCAB_RS22765	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SCAB_RS22770	COG0047	phosphoribosylformylglycinamidine synthase activity
SCAB_RS22775	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SCAB_RS22800	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SCAB_RS22835	COG1643	Atp-dependent helicase
SCAB_RS22875	COG0513	Belongs to the DEAD box helicase family
SCAB_RS23115	COG0629	single-stranded DNA binding
SCAB_RS23165	COG0582	viral genome integration into host DNA
SCAB_RS23220	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SCAB_RS23240	COG0297	glycogen (starch) synthase activity
SCAB_RS23245	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SCAB_RS23270	COG1028	Short-chain dehydrogenase reductase Sdr
SCAB_RS23275	COG0667	Aldo Keto reductase
SCAB_RS23280	COG1028	Short-chain dehydrogenase reductase Sdr
SCAB_RS23305	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SCAB_RS23350	COG1136	(ABC) transporter
SCAB_RS23370	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SCAB_RS23370	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SCAB_RS23380	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SCAB_RS23405	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SCAB_RS23410	COG0579	oxidoreductase
SCAB_RS23435	COG1252	NADH dehydrogenase
SCAB_RS23515	COG1196	nuclear chromosome segregation
SCAB_RS23515	COG0741	lytic transglycosylase activity
SCAB_RS23515	COG0739	heme binding
SCAB_RS23520	COG0671	phosphoesterase, PA-phosphatase related
SCAB_RS23525	COG0277	FAD linked oxidase domain protein
SCAB_RS23545	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SCAB_RS23550	COG0306	phosphate transporter
SCAB_RS23560	COG1937	Protein conserved in bacteria
SCAB_RS23575	COG0406	alpha-ribazole phosphatase activity
SCAB_RS23575	COG0494	nUDIX hydrolase
SCAB_RS23585	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
SCAB_RS23600	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
SCAB_RS23605	COG1725	Transcriptional regulator
SCAB_RS23610	COG0456	acetyltransferase
SCAB_RS23615	COG0737	Belongs to the 5'-nucleotidase family
SCAB_RS23630	COG0745	RESPONSE REGULATOR receiver
SCAB_RS23640	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SCAB_RS23645	COG1609	Transcriptional regulator
SCAB_RS23650	COG0745	RESPONSE REGULATOR receiver
SCAB_RS23675	COG2897	thiosulfate sulfurtransferase activity
SCAB_RS23700	COG3485	protocatechuate 3,4-dioxygenase
SCAB_RS23705	COG0735	belongs to the Fur family
SCAB_RS23715	COG1490	D-aminoacyl-tRNA deacylase activity
SCAB_RS23725	COG4552	Acetyltransferase involved in intracellular survival and related
SCAB_RS23730	COG2188	Transcriptional regulator
SCAB_RS23740	COG2188	Transcriptional regulator
SCAB_RS23755	COG1309	transcriptional regulator
SCAB_RS23770	COG2318	DinB family
SCAB_RS23800	COG0791	NLP P60 protein
SCAB_RS23810	COG0438	transferase activity, transferring glycosyl groups
SCAB_RS23835	COG0588	phosphoglycerate mutase activity
SCAB_RS23875	COG5002	protein histidine kinase activity
SCAB_RS23890	COG1329	Transcriptional regulator
SCAB_RS23895	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
SCAB_RS23900	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
SCAB_RS23905	COG0215	cysteine-tRNA ligase activity
SCAB_RS23910	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SCAB_RS23930	COG3842	ATPase activity
SCAB_RS23950	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SCAB_RS23990	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SCAB_RS24020	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
SCAB_RS24030	COG2182	Extracellular solute-binding protein
SCAB_RS24050	COG0463	Glycosyl transferase, family 2
SCAB_RS24065	COG1278	Cold shock
SCAB_RS24070	COG0459	protein refolding
SCAB_RS24115	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SCAB_RS24145	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
SCAB_RS24150	COG1737	Transcriptional regulator
SCAB_RS24205	COG3973	AAA domain
SCAB_RS24215	COG1061	Type III restriction enzyme res subunit
SCAB_RS24255	COG1278	Cold shock
SCAB_RS24260	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
SCAB_RS24265	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SCAB_RS24275	COG2814	Major facilitator Superfamily
SCAB_RS24310	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SCAB_RS24325	COG2252	PERMEase
SCAB_RS24350	COG0667	Aldo Keto reductase
SCAB_RS24385	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
SCAB_RS24395	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
SCAB_RS24420	COG0247	lactate metabolic process
SCAB_RS24420	COG0277	FAD linked oxidase domain protein
SCAB_RS24470	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SCAB_RS24485	COG0318	PFAM AMP-dependent synthetase and ligase
SCAB_RS24490	COG1024	Enoyl-CoA hydratase
SCAB_RS24500	COG0259	pyridoxamine-phosphate oxidase activity
SCAB_RS24525	COG4821	SIS domain
SCAB_RS24535	COG0596	Alpha beta hydrolase
SCAB_RS24535	COG2945	thiolester hydrolase activity
SCAB_RS24540	COG2826	transposase and inactivated derivatives, IS30 family
SCAB_RS24585	COG1366	Belongs to the anti-sigma-factor antagonist family
SCAB_RS24595	COG0318	PFAM AMP-dependent synthetase and ligase
SCAB_RS24605	COG1960	acyl-CoA dehydrogenase activity
SCAB_RS24610	COG1960	acyl-CoA dehydrogenase activity
SCAB_RS24625	COG1028	Short-chain dehydrogenase reductase Sdr
SCAB_RS24630	COG1960	acyl-CoA dehydrogenase activity
SCAB_RS24650	COG1024	Enoyl-CoA hydratase
SCAB_RS24660	COG2072	flavoprotein involved in K transport
SCAB_RS24700	COG0259	pyridoxamine-phosphate oxidase activity
SCAB_RS24710	COG1960	acyl-CoA dehydrogenase activity
SCAB_RS24720	COG1309	transcriptional regulator
SCAB_RS24730	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SCAB_RS24730	COG0515	serine threonine protein kinase
SCAB_RS24750	COG1024	Enoyl-CoA hydratase
SCAB_RS24780	COG3629	intracellular signal transduction
SCAB_RS24780	COG3903	Transcriptional regulator
SCAB_RS24805	COG2197	response regulator
SCAB_RS24830	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
SCAB_RS24835	COG1012	belongs to the aldehyde dehydrogenase family
SCAB_RS24850	COG4257	antibiotic catabolic process
SCAB_RS24855	COG2226	methyltransferase
SCAB_RS24885	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SCAB_RS24895	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SCAB_RS24920	COG3896	Chloramphenicol phosphotransferase-like protein
SCAB_RS24955	COG1686	Belongs to the peptidase S11 family
SCAB_RS24970	COG0386	Belongs to the glutathione peroxidase family
SCAB_RS25055	COG2249	NAD(P)H dehydrogenase (quinone) activity
SCAB_RS25145	COG4584	PFAM Integrase catalytic
SCAB_RS25160	COG4974	Belongs to the 'phage' integrase family
SCAB_RS25175	COG4555	ABC transporter
SCAB_RS25195	COG1414	Transcriptional regulator
SCAB_RS25215	COG1846	Transcriptional regulator
SCAB_RS25220	COG3384	dioxygenase
SCAB_RS25230	COG1247	-acetyltransferase
SCAB_RS25245	COG0477	Major facilitator Superfamily
SCAB_RS25250	COG1349	DNA-binding transcription factor activity
SCAB_RS25260	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SCAB_RS25260	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SCAB_RS25275	COG1376	ErfK ybiS ycfS ynhG family protein
SCAB_RS25295	COG1970	mechanosensitive ion channel activity
SCAB_RS25305	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SCAB_RS25320	COG3263	regulation of cellular component size
SCAB_RS25330	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SCAB_RS25335	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SCAB_RS25345	COG0315	cyclic pyranopterin monophosphate synthase activity
SCAB_RS25350	COG0315	cyclic pyranopterin monophosphate synthase activity
SCAB_RS25350	COG0521	Mo-molybdopterin cofactor biosynthetic process
SCAB_RS25355	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SCAB_RS25380	COG0708	Exodeoxyribonuclease III
SCAB_RS25395	COG2072	flavoprotein involved in K transport
SCAB_RS25415	COG4946	Tricorn protease homolog
SCAB_RS25415	COG0793	Belongs to the peptidase S41A family
SCAB_RS25425	COG2409	Drug exporters of the RND superfamily
SCAB_RS25430	COG2318	DinB family
SCAB_RS25455	COG0310	cobalt ion transport
SCAB_RS25465	COG1122	ATPase activity
SCAB_RS25470	COG1846	Transcriptional regulator
SCAB_RS25475	COG1764	response to oxidative stress
SCAB_RS25530	COG2186	Transcriptional regulator
SCAB_RS25560	COG0442	prolyl-tRNA aminoacylation
SCAB_RS25575	COG0768	penicillin binding
SCAB_RS25580	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
SCAB_RS25645	COG2188	Transcriptional regulator
SCAB_RS25650	COG1434	Gram-negative-bacterium-type cell wall biogenesis
SCAB_RS25680	COG0084	hydrolase, TatD family'
SCAB_RS25690	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SCAB_RS25695	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SCAB_RS25710	COG0488	(ABC) transporter
SCAB_RS25730	COG1725	Transcriptional regulator
SCAB_RS25735	COG1131	(ABC) transporter
SCAB_RS25745	COG1404	Belongs to the peptidase S8 family
SCAB_RS25760	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
SCAB_RS25770	COG2197	response regulator
SCAB_RS25780	COG4106	trans-aconitate 2-methyltransferase activity
SCAB_RS25785	COG0477	Major facilitator Superfamily
SCAB_RS25795	COG0438	transferase activity, transferring glycosyl groups
SCAB_RS25800	COG1309	transcriptional regulator
SCAB_RS25810	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
SCAB_RS25820	COG0193	aminoacyl-tRNA hydrolase activity
SCAB_RS25825	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
SCAB_RS25830	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SCAB_RS25835	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SCAB_RS25845	COG4585	Histidine kinase
SCAB_RS25875	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SCAB_RS25885	COG0477	Major facilitator Superfamily
SCAB_RS25890	COG1136	(ABC) transporter
SCAB_RS25895	COG0577	efflux transmembrane transporter activity
SCAB_RS25960	COG0148	phosphopyruvate hydratase activity
SCAB_RS25980	COG1252	NADH dehydrogenase
SCAB_RS25985	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SCAB_RS25990	COG0577	efflux transmembrane transporter activity
SCAB_RS25995	COG1136	(ABC) transporter
SCAB_RS26025	COG0183	Belongs to the thiolase family
SCAB_RS26030	COG2755	lipolytic protein G-D-S-L family
SCAB_RS26045	COG2986	histidine ammonia-lyase
SCAB_RS26090	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
SCAB_RS26095	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SCAB_RS26105	COG1228	amidohydrolase
SCAB_RS26115	COG1191	sigma factor activity
SCAB_RS26120	COG1366	Belongs to the anti-sigma-factor antagonist family
SCAB_RS26140	COG3104	oligopeptide transport
SCAB_RS26145	COG0745	RESPONSE REGULATOR receiver
SCAB_RS26150	COG2205	protein histidine kinase activity
SCAB_RS26165	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SCAB_RS26190	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SCAB_RS26205	COG1316	TRANSCRIPTIONal
SCAB_RS26210	COG1316	TRANSCRIPTIONal
SCAB_RS26225	COG1316	TRANSCRIPTIONal
SCAB_RS26255	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
SCAB_RS26255	COG0778	Nitroreductase
SCAB_RS26260	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SCAB_RS26315	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
SCAB_RS26355	COG0714	Associated with various cellular activities
SCAB_RS26375	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
SCAB_RS26380	COG0745	RESPONSE REGULATOR receiver
SCAB_RS26385	COG5000	phosphorelay sensor kinase activity
SCAB_RS26385	COG5002	protein histidine kinase activity
SCAB_RS26390	COG0823	Involved in the tonB-independent uptake of proteins
SCAB_RS26400	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SCAB_RS26405	COG2197	response regulator
SCAB_RS26410	COG3214	Protein conserved in bacteria
SCAB_RS26420	COG0653	protein targeting
SCAB_RS26445	COG2902	Dehydrogenase
SCAB_RS26460	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SCAB_RS26465	COG0438	transferase activity, transferring glycosyl groups
SCAB_RS26470	COG1134	teichoic acid transport
SCAB_RS26510	COG1215	transferase activity, transferring glycosyl groups
SCAB_RS26515	COG1846	Transcriptional regulator
SCAB_RS26520	COG1764	response to oxidative stress
SCAB_RS26530	COG1216	Glycosyl transferase, family 2
SCAB_RS26535	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SCAB_RS26540	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SCAB_RS26540	COG0463	Glycosyl transferase, family 2
SCAB_RS26545	COG0395	ABC-type sugar transport system, permease component
SCAB_RS26550	COG1175	transmembrane transport
SCAB_RS26555	COG1653	transport
SCAB_RS26565	COG0515	serine threonine protein kinase
SCAB_RS26570	COG0515	serine threonine protein kinase
SCAB_RS26575	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SCAB_RS26590	COG2884	Cell division ATP-binding protein ftsE
SCAB_RS26600	COG0793	Belongs to the peptidase S41A family
SCAB_RS26605	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SCAB_RS26615	COG1501	Belongs to the glycosyl hydrolase 31 family
SCAB_RS26650	COG2223	nitrite transmembrane transporter activity
SCAB_RS26675	COG3973	AAA domain
SCAB_RS26685	COG0776	regulation of translation
SCAB_RS26690	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SCAB_RS26695	COG1678	Uncharacterized ACR, COG1678
SCAB_RS26705	COG1653	transport
SCAB_RS26710	COG1175	transmembrane transport
SCAB_RS26715	COG0395	ABC-type sugar transport system, permease component
SCAB_RS26720	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SCAB_RS26735	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SCAB_RS26755	COG2188	Transcriptional regulator
SCAB_RS26855	COG3654	unkown
SCAB_RS26890	COG3185	4-Hydroxyphenylpyruvate dioxygenase
SCAB_RS26900	COG0277	FAD linked oxidase domain protein
SCAB_RS26935	COG1335	isochorismatase
SCAB_RS26945	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
SCAB_RS26955	COG1113	amino acid transport
SCAB_RS26990	COG1263	PTS System
SCAB_RS26995	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SCAB_RS27010	COG2124	cytochrome p450
SCAB_RS27045	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
SCAB_RS27055	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SCAB_RS27060	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
SCAB_RS27070	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SCAB_RS27100	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SCAB_RS27130	COG2733	membrane
SCAB_RS27135	COG2271	Major facilitator Superfamily
SCAB_RS27285	COG3764	Sortase (surface protein transpeptidase)
SCAB_RS27295	COG0706	membrane insertase activity
SCAB_RS27300	COG4702	Belongs to the UPF0303 family
SCAB_RS27305	COG0673	inositol 2-dehydrogenase activity
SCAB_RS27385	COG3397	chitin binding
SCAB_RS27395	COG0318	PFAM AMP-dependent synthetase and ligase
SCAB_RS27405	COG2197	response regulator
SCAB_RS27420	COG1126	abc transporter atp-binding protein
SCAB_RS27425	COG0765	amino acid transport
SCAB_RS27430	COG0765	amino acid transport
SCAB_RS27435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SCAB_RS27440	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SCAB_RS27450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SCAB_RS27495	COG0588	phosphoglycerate mutase activity
SCAB_RS27510	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
SCAB_RS27520	COG0745	RESPONSE REGULATOR receiver
SCAB_RS27530	COG1653	transport
SCAB_RS27540	COG0395	ABC-type sugar transport system, permease component
SCAB_RS27565	COG0395	ABC-type sugar transport system, permease component
SCAB_RS27590	COG1725	Transcriptional regulator
SCAB_RS27615	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
SCAB_RS27620	COG4977	sequence-specific DNA binding
SCAB_RS27630	COG0589	response to stress
SCAB_RS27635	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SCAB_RS27670	COG3486	L-lysine 6-monooxygenase (NADPH) activity
SCAB_RS27675	COG0076	glutamate decarboxylase activity
SCAB_RS27695	COG1960	acyl-CoA dehydrogenase activity
SCAB_RS27710	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SCAB_RS27715	COG1309	transcriptional regulator
SCAB_RS27725	COG1946	Acyl-CoA thioesterase
SCAB_RS27745	COG0028	Belongs to the TPP enzyme family
SCAB_RS27765	COG2356	endonuclease I
SCAB_RS27785	COG2226	methyltransferase
SCAB_RS27795	COG1366	Belongs to the anti-sigma-factor antagonist family
SCAB_RS27825	COG1472	Belongs to the glycosyl hydrolase 3 family
SCAB_RS27840	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SCAB_RS27840	COG0723	plastoquinol--plastocyanin reductase activity
SCAB_RS27850	COG2890	protein-(glutamine-N5) methyltransferase activity
SCAB_RS27875	COG0673	inositol 2-dehydrogenase activity
SCAB_RS27955	COG3629	intracellular signal transduction
SCAB_RS27955	COG3903	Transcriptional regulator
SCAB_RS27960	COG3842	ATPase activity
SCAB_RS27970	COG1840	ABC-type Fe3 transport system, periplasmic component
SCAB_RS27980	COG1674	ftsk spoiiie
SCAB_RS28010	COG1869	D-ribose catabolic process
SCAB_RS28015	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SCAB_RS28025	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SCAB_RS28050	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SCAB_RS28075	COG2409	Drug exporters of the RND superfamily
SCAB_RS28100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SCAB_RS28110	COG3718	enzyme involved in inositol metabolism
SCAB_RS28115	COG3962	Belongs to the TPP enzyme family
SCAB_RS28175	COG0492	ferredoxin-NADP+ reductase activity
SCAB_RS28210	COG0728	peptidoglycan biosynthetic process
SCAB_RS28220	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SCAB_RS28225	COG0297	glycogen (starch) synthase activity
SCAB_RS28270	COG2304	oxidoreductase activity
SCAB_RS28295	COG0629	single-stranded DNA binding
SCAB_RS28325	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SCAB_RS28355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SCAB_RS28370	COG1486	melibiose metabolic process
SCAB_RS28375	COG0395	ABC-type sugar transport system, permease component
SCAB_RS28380	COG1175	transmembrane transport
SCAB_RS28405	COG0668	transmembrane transport
SCAB_RS28415	COG1136	(ABC) transporter
SCAB_RS28440	COG1846	Transcriptional regulator
SCAB_RS28445	COG0697	spore germination
SCAB_RS28500	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
SCAB_RS28510	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SCAB_RS28520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SCAB_RS28525	COG1116	anion transmembrane transporter activity
SCAB_RS28530	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SCAB_RS28555	COG0515	serine threonine protein kinase
SCAB_RS28560	COG1113	amino acid transport
SCAB_RS28580	COG4552	Acetyltransferase involved in intracellular survival and related
SCAB_RS28595	COG3594	Acyltransferase
SCAB_RS28615	COG0544	peptidyl-prolyl cis-trans isomerase activity
SCAB_RS28620	COG0740	serine-type endopeptidase activity
SCAB_RS28625	COG0740	serine-type endopeptidase activity
SCAB_RS28630	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SCAB_RS28645	COG0525	valine-tRNA ligase activity
SCAB_RS28650	COG0285	dihydrofolate synthase activity
SCAB_RS28660	COG0105	UTP biosynthetic process
SCAB_RS28665	COG1077	Cell shape determining protein MreB Mrl
SCAB_RS28680	COG0768	penicillin binding
SCAB_RS28685	COG0772	Belongs to the SEDS family
SCAB_RS28710	COG0457	Tetratricopeptide repeat
SCAB_RS28710	COG0463	Glycosyl transferase, family 2
SCAB_RS28725	COG1530	ribonuclease E activity
SCAB_RS28730	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SCAB_RS28735	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SCAB_RS28740	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SCAB_RS28745	COG2826	transposase and inactivated derivatives, IS30 family
SCAB_RS28755	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SCAB_RS28765	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SCAB_RS28780	COG0501	Belongs to the peptidase M48B family
SCAB_RS28795	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SCAB_RS28805	COG0799	negative regulation of ribosome biogenesis
SCAB_RS28810	COG0588	phosphoglycerate mutase activity
SCAB_RS28830	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SCAB_RS28840	COG0495	leucyl-tRNA aminoacylation
SCAB_RS28850	COG1307	EDD domain protein, DegV family
SCAB_RS28855	COG1555	photosystem II stabilization
SCAB_RS29000	COG1215	transferase activity, transferring glycosyl groups
SCAB_RS29325	COG2188	Transcriptional regulator
SCAB_RS29365	COG0268	Binds directly to 16S ribosomal RNA
SCAB_RS29370	COG0481	GTPase activity
SCAB_RS29415	COG1420	regulation of RNA biosynthetic process
SCAB_RS29420	COG0484	heat shock protein binding
SCAB_RS29445	COG4946	Tricorn protease homolog
SCAB_RS29445	COG0793	Belongs to the peptidase S41A family
SCAB_RS29450	COG0537	adenosine 5'-monophosphoramidase activity
SCAB_RS29455	COG1234	tRNA 3'-trailer cleavage
SCAB_RS29460	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SCAB_RS29470	COG4948	Mandelate Racemase Muconate Lactonizing
SCAB_RS29475	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SCAB_RS29480	COG1414	Transcriptional regulator
SCAB_RS29490	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SCAB_RS29500	COG2315	Protein conserved in bacteria
SCAB_RS29525	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SCAB_RS29565	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SCAB_RS29575	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SCAB_RS29590	COG3903	Transcriptional regulator
SCAB_RS29590	COG3629	intracellular signal transduction
SCAB_RS29600	COG1381	Involved in DNA repair and RecF pathway recombination
SCAB_RS29605	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SCAB_RS29620	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SCAB_RS29625	COG1121	(ABC) transporter
SCAB_RS29635	COG0423	glycine-tRNA ligase activity
SCAB_RS29665	COG0477	Major facilitator Superfamily
SCAB_RS29690	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
SCAB_RS29695	COG1846	Transcriptional regulator
SCAB_RS29695	COG1940	carbohydrate kinase activity
SCAB_RS29700	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SCAB_RS29700	COG0574	Belongs to the PEP-utilizing enzyme family
SCAB_RS29740	COG0642	Histidine kinase
SCAB_RS29745	COG0745	RESPONSE REGULATOR receiver
SCAB_RS29755	COG0659	secondary active sulfate transmembrane transporter activity
SCAB_RS29760	COG1028	Short-chain dehydrogenase reductase Sdr
SCAB_RS29770	COG2146	nitrite reductase [NAD(P)H] activity
SCAB_RS29770	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SCAB_RS29775	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SCAB_RS29810	COG0701	Predicted permease
SCAB_RS29825	COG0243	molybdopterin cofactor binding
SCAB_RS29835	COG2949	membrane
SCAB_RS29845	COG0232	Belongs to the dGTPase family. Type 2 subfamily
SCAB_RS29860	COG0358	DNA primase activity
SCAB_RS29865	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SCAB_RS29880	COG1070	Carbohydrate kinase
SCAB_RS29920	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
SCAB_RS29925	COG1396	sequence-specific DNA binding
SCAB_RS29935	COG1028	Short-chain dehydrogenase reductase Sdr
SCAB_RS29945	COG3852	Histidine kinase
SCAB_RS29965	COG0477	Major facilitator Superfamily
SCAB_RS29995	COG0531	amino acid
SCAB_RS30005	COG1113	amino acid transport
SCAB_RS30035	COG0318	PFAM AMP-dependent synthetase and ligase
SCAB_RS30055	COG0604	alcohol dehydrogenase
SCAB_RS30055	COG3321	synthase
SCAB_RS30060	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SCAB_RS30110	COG1013	pyruvate-flavodoxin oxidoreductase activity
SCAB_RS30115	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SCAB_RS30115	COG0674	pyruvate-flavodoxin oxidoreductase activity
SCAB_RS30125	COG2409	Drug exporters of the RND superfamily
SCAB_RS30130	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SCAB_RS30145	COG2197	response regulator
SCAB_RS30150	COG4585	Histidine kinase
SCAB_RS30175	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
SCAB_RS30185	COG0477	Major facilitator Superfamily
SCAB_RS30190	COG0738	Major facilitator superfamily
SCAB_RS30200	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SCAB_RS30210	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SCAB_RS30235	COG2409	Drug exporters of the RND superfamily
SCAB_RS30240	COG1309	transcriptional regulator
SCAB_RS30260	COG1053	succinate dehydrogenase
SCAB_RS30270	COG3629	intracellular signal transduction
SCAB_RS30270	COG3903	Transcriptional regulator
SCAB_RS30305	COG1077	Cell shape determining protein MreB Mrl
SCAB_RS30310	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SCAB_RS30310	COG0825	malonyl-CoA metabolic process
SCAB_RS30315	COG0318	PFAM AMP-dependent synthetase and ligase
SCAB_RS30370	COG2835	tetraacyldisaccharide 4'-kinase activity
SCAB_RS30390	COG4981	capsule polysaccharide biosynthetic process
SCAB_RS30415	COG1414	Transcriptional regulator
SCAB_RS30420	COG3386	PFAM SMP-30 Gluconolaconase
SCAB_RS30470	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SCAB_RS30480	COG4214	carbohydrate transport
SCAB_RS30485	COG1129	ABC transporter
SCAB_RS30490	COG4213	ABC transporter substrate-binding protein
SCAB_RS30515	COG1609	Transcriptional regulator
SCAB_RS30520	COG1879	ABC-type sugar transport system periplasmic component
SCAB_RS30530	COG1172	Belongs to the binding-protein-dependent transport system permease family
SCAB_RS30535	COG1172	Belongs to the binding-protein-dependent transport system permease family
SCAB_RS30550	COG2130	NADP-dependent
SCAB_RS30585	COG1309	transcriptional regulator
SCAB_RS30605	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SCAB_RS30610	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SCAB_RS30615	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SCAB_RS30630	COG1741	Belongs to the pirin family
SCAB_RS30650	COG0789	Transcriptional regulator
SCAB_RS30655	COG0667	Aldo Keto reductase
SCAB_RS30670	COG1309	transcriptional regulator
SCAB_RS30675	COG0477	Major facilitator Superfamily
SCAB_RS30685	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SCAB_RS30690	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
SCAB_RS30735	COG1358	cellular component organization or biogenesis
SCAB_RS30745	COG0586	Pfam SNARE associated Golgi protein
SCAB_RS30755	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SCAB_RS30800	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SCAB_RS31135	COG1733	regulation of RNA biosynthetic process
SCAB_RS31180	COG4122	O-methyltransferase activity
SCAB_RS31195	COG2124	cytochrome p450
SCAB_RS31200	COG0183	Belongs to the thiolase family
SCAB_RS31205	COG4249	Peptidase C14 caspase catalytic subunit p20
SCAB_RS31205	COG2319	Wd-40 repeat
SCAB_RS31220	COG1404	Belongs to the peptidase S8 family
SCAB_RS31255	COG1309	transcriptional regulator
SCAB_RS31280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SCAB_RS31305	COG0477	Major facilitator Superfamily
SCAB_RS31320	COG2197	response regulator
SCAB_RS31325	COG4585	Histidine kinase
SCAB_RS31330	COG2030	dehydratase
SCAB_RS31340	COG1028	Short-chain dehydrogenase reductase Sdr
SCAB_RS31350	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
SCAB_RS31365	COG0800	Aldolase
SCAB_RS31370	COG3022	response to hydroperoxide
SCAB_RS31505	COG1401	restriction endodeoxyribonuclease activity
SCAB_RS31530	COG3940	Belongs to the glycosyl hydrolase 43 family
SCAB_RS31535	COG3940	Belongs to the glycosyl hydrolase 43 family
SCAB_RS31540	COG2197	response regulator
SCAB_RS31545	COG4585	Histidine kinase
SCAB_RS31550	COG2409	Drug exporters of the RND superfamily
SCAB_RS31565	COG2259	Doxx family
SCAB_RS31580	COG1028	Short-chain dehydrogenase reductase Sdr
SCAB_RS31585	COG3540	Alkaline phosphatase
SCAB_RS31595	COG2814	Major facilitator Superfamily
SCAB_RS31600	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SCAB_RS31630	COG0672	)-iron permease
SCAB_RS31635	COG2837	iron assimilation
SCAB_RS31680	COG1994	Peptidase M50
SCAB_RS31700	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
SCAB_RS31705	COG0477	Major facilitator Superfamily
SCAB_RS31720	COG2814	Major facilitator Superfamily
SCAB_RS31730	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SCAB_RS31730	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SCAB_RS31745	COG0174	glutamine synthetase
SCAB_RS31765	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
SCAB_RS31775	COG0583	DNA-binding transcription factor activity
SCAB_RS31785	COG1609	Transcriptional regulator
SCAB_RS31795	COG1175	transmembrane transport
SCAB_RS31800	COG3833	ABC-type maltose transport systems, permease component
SCAB_RS31805	COG0366	Alpha amylase catalytic
SCAB_RS31860	COG1309	transcriptional regulator
SCAB_RS31885	COG0745	RESPONSE REGULATOR receiver
SCAB_RS31935	COG0174	glutamine synthetase
SCAB_RS31955	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SCAB_RS31960	COG0321	lipoyl(octanoyl) transferase activity
SCAB_RS31985	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SCAB_RS32010	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
SCAB_RS32020	COG0508	dehydrogenase complex catalyzes the overall conversion of
SCAB_RS32025	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SCAB_RS32030	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SCAB_RS32055	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SCAB_RS32095	COG4585	Histidine kinase
SCAB_RS32100	COG2197	response regulator
SCAB_RS32105	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SCAB_RS32110	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
SCAB_RS32130	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SCAB_RS32140	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
SCAB_RS32145	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SCAB_RS32155	COG1376	ErfK ybiS ycfS ynhG family protein
SCAB_RS32165	COG1845	cytochrome c oxidase, subunit III
SCAB_RS32170	COG2010	Cytochrome c
SCAB_RS32175	COG0723	plastoquinol--plastocyanin reductase activity
SCAB_RS32180	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SCAB_RS32185	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SCAB_RS32190	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SCAB_RS32260	COG0003	Pfam Anion-transporting ATPase
SCAB_RS32270	COG1940	carbohydrate kinase activity
SCAB_RS32295	COG4585	Histidine kinase
SCAB_RS32300	COG2197	response regulator
SCAB_RS32305	COG0205	6-phosphofructokinase activity
SCAB_RS32320	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
SCAB_RS32325	COG0243	molybdopterin cofactor binding
SCAB_RS32330	COG2193	ferroxidase activity
SCAB_RS32335	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SCAB_RS32340	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
SCAB_RS32345	COG2815	serine threonine protein kinase
SCAB_RS32345	COG0515	serine threonine protein kinase
SCAB_RS32350	COG2022	thiamine diphosphate biosynthetic process
SCAB_RS32360	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SCAB_RS32360	COG2022	thiamine diphosphate biosynthetic process
SCAB_RS32380	COG0352	thiamine-phosphate diphosphorylase activity
SCAB_RS32400	COG1309	transcriptional regulator
SCAB_RS32410	COG1129	ABC transporter
SCAB_RS32420	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SCAB_RS32440	COG0714	Associated with various cellular activities
SCAB_RS32450	COG0275	rRNA processing
SCAB_RS32465	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SCAB_RS32475	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SCAB_RS32480	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SCAB_RS32490	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SCAB_RS32495	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
SCAB_RS32500	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SCAB_RS32505	COG1496	oxidoreductase activity
SCAB_RS32510	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SCAB_RS32515	COG1799	cell septum assembly
SCAB_RS32525	COG3599	regulation of cell shape
SCAB_RS32530	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SCAB_RS32540	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SCAB_RS32605	COG0587	DNA-directed DNA polymerase activity
SCAB_RS32610	COG1432	Conserved Protein
SCAB_RS32630	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SCAB_RS32650	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SCAB_RS32655	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SCAB_RS32660	COG0131	Imidazoleglycerol-phosphate dehydratase
SCAB_RS32670	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SCAB_RS32675	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SCAB_RS32680	COG0251	oxidation-reduction process
SCAB_RS32685	COG0107	imidazoleglycerol-phosphate synthase activity
SCAB_RS32695	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SCAB_RS32700	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SCAB_RS32720	COG0134	indole-3-glycerol-phosphate synthase activity
SCAB_RS32725	COG0133	tryptophan synthase activity
SCAB_RS32730	COG0159	tryptophan synthase activity
SCAB_RS32740	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SCAB_RS32745	COG2301	Belongs to the HpcH HpaI aldolase family
SCAB_RS32750	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SCAB_RS32780	COG0069	glutamate synthase activity
SCAB_RS32780	COG0067	glutamate synthase
SCAB_RS32780	COG0070	glutamate synthase
SCAB_RS32795	COG2304	oxidoreductase activity
SCAB_RS32800	COG1960	acyl-CoA dehydrogenase activity
SCAB_RS32805	COG1960	acyl-CoA dehydrogenase activity
SCAB_RS32810	COG1028	Short-chain dehydrogenase reductase Sdr
SCAB_RS32815	COG1309	transcriptional regulator
SCAB_RS32820	COG0183	Belongs to the thiolase family
SCAB_RS32840	COG1024	Enoyl-CoA hydratase
SCAB_RS32850	COG1028	Short-chain dehydrogenase reductase Sdr
SCAB_RS32860	COG1605	Chorismate mutase
SCAB_RS32860	COG0287	Prephenate dehydrogenase
SCAB_RS32865	COG4566	intracellular signal transduction
SCAB_RS32885	COG3293	Transposase
SCAB_RS32895	COG0737	Belongs to the 5'-nucleotidase family
SCAB_RS32930	COG0411	ABC transporter
SCAB_RS32960	COG2050	protein possibly involved in aromatic compounds catabolism
SCAB_RS32990	COG1643	Atp-dependent helicase
SCAB_RS33000	COG0539	negative regulation of cytoplasmic translation
SCAB_RS33010	COG0237	dephospho-CoA kinase activity
SCAB_RS33030	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SCAB_RS33050	COG2267	carboxylic ester hydrolase activity
SCAB_RS33055	COG1802	Transcriptional regulator
SCAB_RS33060	COG1953	Uracil, thiamine, allantoin
SCAB_RS33085	COG1132	(ABC) transporter
SCAB_RS33115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SCAB_RS33120	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SCAB_RS33150	COG0598	Magnesium transport protein CorA
SCAB_RS33155	COG2226	methyltransferase
SCAB_RS33160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SCAB_RS33165	COG2313	pseudouridylate synthase activity
SCAB_RS33175	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SCAB_RS33180	COG0584	glycerophosphoryl diester phosphodiesterase
SCAB_RS33190	COG0556	nucleotide-excision repair
SCAB_RS33210	COG0387	Pfam Sodium calcium exchanger
SCAB_RS33215	COG0477	Major facilitator Superfamily
SCAB_RS33220	COG1619	proteins homologs of microcin C7 resistance protein MccF
SCAB_RS33225	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
SCAB_RS33235	COG0765	amino acid transport
SCAB_RS33240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SCAB_RS33255	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SCAB_RS33275	COG2201	protein-glutamate methylesterase activity
SCAB_RS33290	COG4585	Histidine kinase
SCAB_RS33295	COG2197	response regulator
SCAB_RS33300	COG0322	excinuclease ABC activity
SCAB_RS33305	COG1660	Displays ATPase and GTPase activities
SCAB_RS33310	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SCAB_RS33315	COG1481	regulation of sporulation
SCAB_RS33325	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SCAB_RS33330	COG0126	phosphoglycerate kinase activity
SCAB_RS33335	COG0149	triose-phosphate isomerase activity
SCAB_RS33340	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SCAB_RS33350	COG0166	Belongs to the GPI family
SCAB_RS33355	COG1028	Short-chain dehydrogenase reductase Sdr
SCAB_RS33360	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SCAB_RS33390	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SCAB_RS33400	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SCAB_RS33405	COG0318	PFAM AMP-dependent synthetase and ligase
SCAB_RS33420	COG0363	glucosamine-6-phosphate deaminase activity
SCAB_RS33435	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SCAB_RS33440	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SCAB_RS33445	COG0109	protoheme IX farnesyltransferase activity
SCAB_RS33465	COG1612	heme a metabolic process
SCAB_RS33475	COG1131	(ABC) transporter
SCAB_RS33480	COG2746	aminoglycoside 3-N-acetyltransferase activity
SCAB_RS33495	COG0719	Fe-S assembly protein
SCAB_RS33505	COG0396	ATPase activity
SCAB_RS33510	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SCAB_RS33515	COG0822	iron-sulfur transferase activity
SCAB_RS33520	COG2151	metal-sulfur cluster biosynthetic enzyme
SCAB_RS33530	COG2076	Multidrug Resistance protein
SCAB_RS33535	COG3226	Transcriptional regulator
SCAB_RS33540	COG2171	N-acyltransferase activity
SCAB_RS33550	COG1595	DNA-templated transcription, initiation
SCAB_RS33560	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SCAB_RS33575	COG1959	2 iron, 2 sulfur cluster binding
SCAB_RS33575	COG1295	ribonuclease BN
SCAB_RS33620	COG1802	Transcriptional regulator
SCAB_RS33640	COG1063	alcohol dehydrogenase
SCAB_RS33645	COG0395	ABC-type sugar transport system, permease component
SCAB_RS33660	COG1349	DNA-binding transcription factor activity
SCAB_RS33665	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SCAB_RS33670	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SCAB_RS33695	COG1802	Transcriptional regulator
SCAB_RS33700	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SCAB_RS33710	COG1175	transmembrane transport
SCAB_RS33715	COG0395	ABC-type sugar transport system, permease component
SCAB_RS33740	COG4677	pectinesterase activity
SCAB_RS33750	COG2755	lipolytic protein G-D-S-L family
SCAB_RS33760	COG4677	pectinesterase activity
SCAB_RS33765	COG4677	pectinesterase activity
SCAB_RS33785	COG1595	DNA-templated transcription, initiation
SCAB_RS33790	COG2252	PERMEase
SCAB_RS33800	COG1414	Transcriptional regulator
SCAB_RS33825	COG1595	DNA-templated transcription, initiation
SCAB_RS33835	COG5285	phytanoyl-CoA dioxygenase
SCAB_RS33840	COG1917	Cupin 2, conserved barrel domain protein
SCAB_RS33845	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SCAB_RS33850	COG0456	acetyltransferase
SCAB_RS33855	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
SCAB_RS33865	COG0765	amino acid transport
SCAB_RS33870	COG1126	abc transporter atp-binding protein
SCAB_RS33900	COG1797	cobyrinic acid a,c-diamide synthase activity
SCAB_RS33915	COG1492	cobalamin metabolic process
SCAB_RS33920	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
SCAB_RS33935	COG0235	Class ii aldolase
SCAB_RS33955	COG0488	(ABC) transporter
SCAB_RS34000	COG1028	Short-chain dehydrogenase reductase Sdr
SCAB_RS34005	COG3387	PFAM Glycoside hydrolase 15-related
SCAB_RS34030	COG1966	Carbon starvation protein
SCAB_RS34055	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SCAB_RS34090	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SCAB_RS34095	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SCAB_RS34115	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SCAB_RS34130	COG1028	Short-chain dehydrogenase reductase Sdr
SCAB_RS34145	COG2186	Transcriptional regulator
SCAB_RS34160	COG0588	phosphoglycerate mutase activity
SCAB_RS34165	COG0560	Phosphoserine phosphatase
SCAB_RS34165	COG3830	Belongs to the UPF0237 family
SCAB_RS34175	COG0842	Transport permease protein
SCAB_RS34175	COG1716	ATPase activity
SCAB_RS34175	COG1131	(ABC) transporter
SCAB_RS34185	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SCAB_RS34190	COG4221	oxidoreductase activity
SCAB_RS34195	COG4585	Histidine kinase
SCAB_RS34200	COG2197	response regulator
SCAB_RS34215	COG1119	ATPase activity
SCAB_RS34235	COG1881	PFAM PEBP family protein
SCAB_RS34245	COG2094	Belongs to the DNA glycosylase MPG family
SCAB_RS34290	COG0647	UMP catabolic process
SCAB_RS34295	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SCAB_RS34300	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SCAB_RS34305	COG1120	ATPase activity
SCAB_RS34325	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SCAB_RS34330	COG0497	DNA recombination
SCAB_RS34335	COG0438	transferase activity, transferring glycosyl groups
SCAB_RS34350	COG3387	PFAM Glycoside hydrolase 15-related
SCAB_RS34355	COG0504	CTP synthase activity
SCAB_RS34360	COG0494	nUDIX hydrolase
SCAB_RS34370	COG0686	Belongs to the AlaDH PNT family
SCAB_RS34385	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
SCAB_RS34390	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
SCAB_RS34395	COG1187	pseudouridine synthase activity
SCAB_RS34400	COG0494	nUDIX hydrolase
SCAB_RS34410	COG3541	Predicted nucleotidyltransferase
SCAB_RS34435	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
SCAB_RS34445	COG1160	GTP binding
SCAB_RS34460	COG3583	domain protein
SCAB_RS34470	COG1137	ATPase activity
SCAB_RS34490	COG0438	transferase activity, transferring glycosyl groups
SCAB_RS34505	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SCAB_RS34515	COG0671	phosphoesterase, PA-phosphatase related
SCAB_RS34525	COG0477	Major facilitator Superfamily
SCAB_RS34530	COG1960	acyl-CoA dehydrogenase activity
SCAB_RS34535	COG1799	cell septum assembly
SCAB_RS34580	COG0587	DNA-directed DNA polymerase activity
SCAB_RS34585	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SCAB_RS34590	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SCAB_RS34590	COG0662	Cupin 2, conserved barrel domain protein
SCAB_RS34625	COG1725	Transcriptional regulator
SCAB_RS34640	COG2755	lipolytic protein G-D-S-L family
SCAB_RS34665	COG1595	DNA-templated transcription, initiation
SCAB_RS34680	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SCAB_RS34705	COG2188	Transcriptional regulator
SCAB_RS34710	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
SCAB_RS34715	COG1309	transcriptional regulator
SCAB_RS34720	COG0243	molybdopterin cofactor binding
SCAB_RS34725	COG2851	Citrate transporter
SCAB_RS34775	COG1960	acyl-CoA dehydrogenase activity
SCAB_RS34805	COG0789	Transcriptional regulator
SCAB_RS34810	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SCAB_RS34810	COG0072	phenylalanine-tRNA ligase activity
SCAB_RS34835	COG3876	Protein conserved in bacteria
SCAB_RS34850	COG1960	acyl-CoA dehydrogenase activity
SCAB_RS34875	COG2149	membrane
SCAB_RS34880	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
SCAB_RS34890	COG3573	Dehydrogenase
SCAB_RS34895	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SCAB_RS34910	COG3265	gluconokinase activity
SCAB_RS34915	COG2186	Transcriptional regulator
SCAB_RS34920	COG3012	SEC-C Motif Domain Protein
SCAB_RS34925	COG0308	aminopeptidase N
SCAB_RS34970	COG0667	Aldo Keto reductase
SCAB_RS34975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SCAB_RS34985	COG0598	Magnesium transport protein CorA
SCAB_RS34990	COG0588	phosphoglycerate mutase activity
SCAB_RS35005	COG0215	cysteine-tRNA ligase activity
SCAB_RS35020	COG2186	Transcriptional regulator
SCAB_RS35025	COG0235	Class ii aldolase
SCAB_RS35025	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
SCAB_RS35030	COG0235	Class ii aldolase
SCAB_RS35035	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
SCAB_RS35040	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
SCAB_RS35045	COG1879	ABC-type sugar transport system periplasmic component
SCAB_RS35050	COG1129	ABC transporter
SCAB_RS35065	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SCAB_RS35070	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SCAB_RS35075	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SCAB_RS35080	COG1414	Transcriptional regulator
SCAB_RS35085	COG0646	methionine synthase
SCAB_RS35085	COG1410	methionine synthase
SCAB_RS35095	COG4166	transmembrane transport
SCAB_RS35100	COG4166	transmembrane transport
SCAB_RS35105	COG2197	response regulator
SCAB_RS35115	COG1994	Peptidase M50
SCAB_RS35115	COG0517	IMP dehydrogenase activity
SCAB_RS35135	COG1222	aaa ATPase
SCAB_RS35140	COG4122	O-methyltransferase activity
SCAB_RS35155	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SCAB_RS35160	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SCAB_RS35165	COG1609	Transcriptional regulator
SCAB_RS35175	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SCAB_RS35215	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SCAB_RS35220	COG0805	protein transport
SCAB_RS35255	COG1309	transcriptional regulator
SCAB_RS35310	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SCAB_RS35335	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SCAB_RS35340	COG0531	amino acid
SCAB_RS35345	COG2186	Transcriptional regulator
SCAB_RS35350	COG0174	glutamine synthetase
SCAB_RS35355	COG1012	belongs to the aldehyde dehydrogenase family
SCAB_RS35380	COG1404	Belongs to the peptidase S8 family
SCAB_RS35400	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SCAB_RS35405	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SCAB_RS35410	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SCAB_RS35415	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SCAB_RS35420	COG5002	protein histidine kinase activity
SCAB_RS35425	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SCAB_RS35430	COG0072	phenylalanine-tRNA ligase activity
SCAB_RS35430	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SCAB_RS35460	COG1649	PFAM Uncharacterised BCR, COG1649
SCAB_RS35470	COG0697	spore germination
SCAB_RS35515	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SCAB_RS35520	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
SCAB_RS35525	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SCAB_RS35530	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SCAB_RS35535	COG1438	arginine binding
SCAB_RS35565	COG0165	Argininosuccinate lyase
SCAB_RS35580	COG0477	Major facilitator Superfamily
SCAB_RS35585	COG0318	PFAM AMP-dependent synthetase and ligase
SCAB_RS35585	COG0204	Acyl-transferase
SCAB_RS35615	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SCAB_RS35620	COG2011	ABC-type metal ion transport system permease component
SCAB_RS35625	COG1464	Belongs to the NlpA lipoprotein family
SCAB_RS35640	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SCAB_RS35645	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SCAB_RS35645	COG1648	precorrin-2 dehydrogenase activity
SCAB_RS35705	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SCAB_RS35705	COG0512	Glutamine amidotransferase of anthranilate synthase
SCAB_RS35755	COG1175	transmembrane transport
SCAB_RS35760	COG0395	ABC-type sugar transport system, permease component
SCAB_RS35790	COG2176	DNA-directed DNA polymerase activity
SCAB_RS35790	COG5002	protein histidine kinase activity
SCAB_RS35805	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SCAB_RS35810	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SCAB_RS35830	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SCAB_RS35835	COG1560	Kdo2-lipid A biosynthetic process
SCAB_RS35840	COG0438	transferase activity, transferring glycosyl groups
SCAB_RS35850	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
SCAB_RS35855	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
SCAB_RS35860	COG0217	transcriptional regulatory protein
SCAB_RS35865	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
SCAB_RS35870	COG0632	four-way junction helicase activity
SCAB_RS35875	COG2255	four-way junction helicase activity
SCAB_RS35885	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SCAB_RS35890	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SCAB_RS35895	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SCAB_RS35905	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SCAB_RS35910	COG1196	nuclear chromosome segregation
SCAB_RS35915	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SCAB_RS35925	COG0124	histidyl-tRNA synthetase
SCAB_RS35940	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SCAB_RS35955	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SCAB_RS35960	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SCAB_RS35965	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SCAB_RS35970	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SCAB_RS35975	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SCAB_RS35980	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SCAB_RS35985	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SCAB_RS36000	COG0006	proline dipeptidase activity
SCAB_RS36005	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SCAB_RS36010	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SCAB_RS36020	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
SCAB_RS36025	COG0540	Belongs to the ATCase OTCase family
SCAB_RS36030	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SCAB_RS36040	COG0505	Belongs to the CarA family
SCAB_RS36045	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SCAB_RS36050	COG0167	dihydroorotate dehydrogenase activity
SCAB_RS36055	COG0284	orotidine-5'-phosphate decarboxylase activity
SCAB_RS36065	COG0194	GDP metabolic process
SCAB_RS36070	COG1758	RNA polymerase activity
SCAB_RS36080	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SCAB_RS36095	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SCAB_RS36105	COG2409	Drug exporters of the RND superfamily
SCAB_RS36110	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SCAB_RS36115	COG2390	Transcriptional regulator
SCAB_RS36125	COG0531	amino acid
SCAB_RS36135	COG2188	Transcriptional regulator
SCAB_RS36155	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
SCAB_RS36170	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SCAB_RS36190	COG2197	response regulator
SCAB_RS36200	COG0738	Major facilitator superfamily
SCAB_RS36205	COG1940	carbohydrate kinase activity
SCAB_RS36205	COG1846	Transcriptional regulator
SCAB_RS36215	COG3201	nicotinamide mononucleotide transporter
SCAB_RS36220	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SCAB_RS36220	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SCAB_RS36225	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
SCAB_RS36230	COG0140	phosphoribosyl-ATP diphosphatase activity
SCAB_RS36235	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SCAB_RS36270	COG1309	transcriptional regulator
SCAB_RS36280	COG1960	acyl-CoA dehydrogenase activity
SCAB_RS36300	COG1216	Glycosyl transferase, family 2
SCAB_RS36315	COG2270	Major facilitator Superfamily
SCAB_RS36325	COG2364	Membrane
SCAB_RS36330	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SCAB_RS36360	COG0438	transferase activity, transferring glycosyl groups
SCAB_RS36370	COG1984	allophanate hydrolase subunit 2
SCAB_RS36375	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
SCAB_RS36380	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
SCAB_RS36385	COG4336	lyase activity
SCAB_RS36390	COG2814	Major facilitator Superfamily
SCAB_RS36420	COG0531	amino acid
SCAB_RS36425	COG1012	belongs to the aldehyde dehydrogenase family
SCAB_RS36440	COG2018	Roadblock/LC7 domain
SCAB_RS36475	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SCAB_RS36485	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SCAB_RS36515	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SCAB_RS36535	COG1716	ATPase activity
SCAB_RS36555	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SCAB_RS36565	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SCAB_RS36565	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SCAB_RS36590	COG0384	phenazine biosynthesis protein PhzF
SCAB_RS36595	COG1028	Short-chain dehydrogenase reductase Sdr
SCAB_RS36635	COG0697	spore germination
SCAB_RS36640	COG0583	DNA-binding transcription factor activity
SCAB_RS36685	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SCAB_RS36700	COG2318	DinB family
SCAB_RS36710	COG0815	Transfers the fatty acyl group on membrane lipoproteins
SCAB_RS36735	COG1028	Short-chain dehydrogenase reductase Sdr
SCAB_RS36770	COG2205	protein histidine kinase activity
SCAB_RS36775	COG0745	RESPONSE REGULATOR receiver
SCAB_RS36780	COG2409	Drug exporters of the RND superfamily
SCAB_RS36785	COG1556	Lactate utilization protein
SCAB_RS36790	COG4569	acetaldehyde dehydrogenase (acetylating) activity
SCAB_RS36795	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SCAB_RS36805	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SCAB_RS36810	COG0730	response to heat
SCAB_RS36815	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SCAB_RS36820	COG1937	Protein conserved in bacteria
SCAB_RS36825	COG1309	transcriptional regulator
SCAB_RS36830	COG1609	Transcriptional regulator
SCAB_RS36835	COG2723	6-phospho-beta-galactosidase activity
SCAB_RS36850	COG1136	(ABC) transporter
SCAB_RS36850	COG0577	efflux transmembrane transporter activity
SCAB_RS36855	COG0577	efflux transmembrane transporter activity
SCAB_RS36855	COG1136	(ABC) transporter
SCAB_RS36865	COG1309	transcriptional regulator
SCAB_RS36870	COG0604	alcohol dehydrogenase
SCAB_RS36870	COG3321	synthase
SCAB_RS36880	COG1028	Short-chain dehydrogenase reductase Sdr
SCAB_RS36925	COG1960	acyl-CoA dehydrogenase activity
SCAB_RS36945	COG1053	succinate dehydrogenase
SCAB_RS36960	COG3940	Belongs to the glycosyl hydrolase 43 family
SCAB_RS36975	COG1472	Belongs to the glycosyl hydrolase 3 family
SCAB_RS36985	COG0395	ABC-type sugar transport system, permease component
SCAB_RS37010	COG1609	Transcriptional regulator
SCAB_RS37025	COG1609	Transcriptional regulator
SCAB_RS37035	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SCAB_RS37045	COG1175	transmembrane transport
SCAB_RS37050	COG0395	ABC-type sugar transport system, permease component
SCAB_RS37075	COG4585	Histidine kinase
SCAB_RS37090	COG1653	transport
SCAB_RS37095	COG1175	transmembrane transport
SCAB_RS37100	COG0395	ABC-type sugar transport system, permease component
SCAB_RS37110	COG3250	beta-galactosidase activity
SCAB_RS37120	COG0596	Alpha beta hydrolase
SCAB_RS37150	COG1968	undecaprenyl-diphosphatase activity
SCAB_RS37175	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SCAB_RS37210	COG0110	maltose O-acetyltransferase activity
SCAB_RS37235	COG0542	response to heat
SCAB_RS37255	COG1832	CoA-binding protein
SCAB_RS37270	COG1739	Uncharacterized protein family UPF0029
SCAB_RS37275	COG0420	3'-5' exonuclease activity
SCAB_RS37280	COG0419	ATPase involved in DNA repair
SCAB_RS37285	COG1522	sequence-specific DNA binding
SCAB_RS37310	COG0626	cystathionine gamma-synthase activity
SCAB_RS37325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SCAB_RS37335	COG2267	carboxylic ester hydrolase activity
SCAB_RS37340	COG1595	DNA-templated transcription, initiation
SCAB_RS37345	COG2188	Transcriptional regulator
SCAB_RS37350	COG1940	carbohydrate kinase activity
SCAB_RS37360	COG3663	DNA glycosylase
SCAB_RS37365	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SCAB_RS37375	COG0445	tRNA wobble uridine modification
SCAB_RS37400	COG0456	acetyltransferase
SCAB_RS37410	COG1136	(ABC) transporter
SCAB_RS37410	COG0577	efflux transmembrane transporter activity
SCAB_RS37415	COG0577	efflux transmembrane transporter activity
SCAB_RS37415	COG1136	(ABC) transporter
SCAB_RS37445	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SCAB_RS37450	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SCAB_RS37455	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SCAB_RS37495	COG0740	serine-type endopeptidase activity
SCAB_RS37515	COG1309	transcriptional regulator
SCAB_RS37520	COG0831	urea catabolic process
SCAB_RS37525	COG0832	Belongs to the urease beta subunit family
SCAB_RS37530	COG0804	urea catabolic process
SCAB_RS37540	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SCAB_RS37545	COG0829	nickel cation binding
SCAB_RS37570	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SCAB_RS37575	COG1834	amidinotransferase
SCAB_RS37595	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SCAB_RS37600	COG3275	phosphorelay sensor kinase activity
SCAB_RS37610	COG2815	serine threonine protein kinase
SCAB_RS37610	COG0515	serine threonine protein kinase
SCAB_RS37625	COG0205	6-phosphofructokinase activity
SCAB_RS37630	COG3442	glutamine amidotransferase
SCAB_RS37640	COG0242	peptide deformylase activity
SCAB_RS37650	COG1960	acyl-CoA dehydrogenase activity
SCAB_RS37660	COG1012	belongs to the aldehyde dehydrogenase family
SCAB_RS37670	COG1793	dna ligase
SCAB_RS37690	COG1960	acyl-CoA dehydrogenase activity
SCAB_RS37695	COG1960	acyl-CoA dehydrogenase activity
SCAB_RS37730	COG0642	Histidine kinase
SCAB_RS37765	COG1846	Transcriptional regulator
SCAB_RS37805	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SCAB_RS37805	COG3321	synthase
SCAB_RS37810	COG0318	PFAM AMP-dependent synthetase and ligase
SCAB_RS37815	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SCAB_RS37830	COG2755	lipolytic protein G-D-S-L family
SCAB_RS37865	COG3284	Transcriptional regulator
SCAB_RS37870	COG1129	ABC transporter
SCAB_RS37875	COG1172	Belongs to the binding-protein-dependent transport system permease family
SCAB_RS37920	COG3033	Beta-eliminating lyase
SCAB_RS37930	COG3693	PFAM glycoside hydrolase, family 10
SCAB_RS37945	COG1408	metallophosphoesterase
SCAB_RS37960	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SCAB_RS37965	COG0247	lactate metabolic process
SCAB_RS37965	COG0277	FAD linked oxidase domain protein
SCAB_RS38020	COG1129	ABC transporter
SCAB_RS38025	COG4211	Belongs to the binding-protein-dependent transport system permease family
SCAB_RS38030	COG1172	Belongs to the binding-protein-dependent transport system permease family
SCAB_RS38035	COG4213	ABC transporter substrate-binding protein
SCAB_RS38065	COG0395	ABC-type sugar transport system, permease component
SCAB_RS38070	COG4948	Mandelate Racemase Muconate Lactonizing
SCAB_RS38115	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SCAB_RS38140	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SCAB_RS38150	COG2124	cytochrome p450
SCAB_RS38155	COG0604	alcohol dehydrogenase
SCAB_RS38160	COG1250	3-hydroxyacyl-CoA dehydrogenase
SCAB_RS38200	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SCAB_RS38205	COG1012	belongs to the aldehyde dehydrogenase family
SCAB_RS38220	COG1940	carbohydrate kinase activity
SCAB_RS38245	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SCAB_RS38295	COG2018	Roadblock/LC7 domain
SCAB_RS38300	COG1946	Acyl-CoA thioesterase
SCAB_RS38325	COG1132	(ABC) transporter
SCAB_RS38345	COG1301	dicarboxylic acid transport
SCAB_RS38355	COG1132	(ABC) transporter
SCAB_RS38360	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SCAB_RS38365	COG2072	flavoprotein involved in K transport
SCAB_RS38370	COG0432	Pfam Uncharacterised protein family UPF0047
SCAB_RS38395	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SCAB_RS38400	COG2801	Transposase and inactivated derivatives
SCAB_RS38415	COG1733	regulation of RNA biosynthetic process
SCAB_RS38440	COG3903	Transcriptional regulator
SCAB_RS38440	COG3629	intracellular signal transduction
SCAB_RS38510	COG2267	carboxylic ester hydrolase activity
SCAB_RS38560	COG4585	Histidine kinase
SCAB_RS38565	COG2197	response regulator
SCAB_RS38585	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SCAB_RS38605	COG2124	cytochrome p450
SCAB_RS38615	COG1595	DNA-templated transcription, initiation
SCAB_RS38625	COG1131	(ABC) transporter
SCAB_RS38650	COG1028	Short-chain dehydrogenase reductase Sdr
SCAB_RS38700	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SCAB_RS38735	COG2197	response regulator
SCAB_RS38770	COG1414	Transcriptional regulator
SCAB_RS38775	COG1414	Transcriptional regulator
SCAB_RS38780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SCAB_RS38785	COG3608	succinylglutamate desuccinylase aspartoacylase
SCAB_RS38795	COG3842	ATPase activity
SCAB_RS38810	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SCAB_RS38815	COG3608	succinylglutamate desuccinylase aspartoacylase
SCAB_RS38820	COG1012	belongs to the aldehyde dehydrogenase family
SCAB_RS38825	COG0667	Aldo Keto reductase
SCAB_RS38835	COG0723	plastoquinol--plastocyanin reductase activity
SCAB_RS38835	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SCAB_RS38855	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SCAB_RS38885	COG1028	Short-chain dehydrogenase reductase Sdr
SCAB_RS38915	COG1233	COG1233 Phytoene dehydrogenase and related
SCAB_RS38970	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SCAB_RS38975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SCAB_RS38985	COG1595	DNA-templated transcription, initiation
SCAB_RS39080	COG1316	TRANSCRIPTIONal
SCAB_RS39095	COG3835	regulator
SCAB_RS39120	COG1174	glycine betaine transport
SCAB_RS39160	COG4172	Belongs to the ABC transporter superfamily
SCAB_RS39165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SCAB_RS39170	COG0601	transmembrane transport
SCAB_RS39175	COG4166	transmembrane transport
SCAB_RS39195	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SCAB_RS39205	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SCAB_RS39215	COG0714	Associated with various cellular activities
SCAB_RS39265	COG2080	2 iron, 2 sulfur cluster binding
SCAB_RS39270	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
SCAB_RS39275	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SCAB_RS39310	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SCAB_RS39315	COG4948	Mandelate Racemase Muconate Lactonizing
SCAB_RS39335	COG0531	amino acid
SCAB_RS39350	COG3396	Phenylacetate-CoA oxygenase
SCAB_RS39355	COG3460	Phenylacetate-CoA oxygenase
SCAB_RS39360	COG3396	Phenylacetate-CoA oxygenase
SCAB_RS39365	COG2151	metal-sulfur cluster biosynthetic enzyme
SCAB_RS39370	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SCAB_RS39400	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SCAB_RS39425	COG3509	depolymerase
SCAB_RS39435	COG0493	'glutamate synthase
SCAB_RS39460	COG0671	phosphoesterase, PA-phosphatase related
SCAB_RS39490	COG0584	glycerophosphoryl diester phosphodiesterase
SCAB_RS39515	COG0204	Acyl-transferase
SCAB_RS39540	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
SCAB_RS39555	COG0515	serine threonine protein kinase
SCAB_RS39580	COG1660	Displays ATPase and GTPase activities
SCAB_RS39590	COG0445	tRNA wobble uridine modification
SCAB_RS39630	COG1349	DNA-binding transcription factor activity
SCAB_RS39635	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SCAB_RS39650	COG2813	Specifically methylates the guanine in position
SCAB_RS39660	COG1940	carbohydrate kinase activity
SCAB_RS39690	COG1349	DNA-binding transcription factor activity
SCAB_RS39730	COG1215	transferase activity, transferring glycosyl groups
SCAB_RS39735	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SCAB_RS39770	COG1309	transcriptional regulator
SCAB_RS39790	COG1253	flavin adenine dinucleotide binding
SCAB_RS39810	COG0714	Associated with various cellular activities
SCAB_RS39830	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SCAB_RS39855	COG1846	Transcriptional regulator
SCAB_RS39865	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SCAB_RS39870	COG3281	Trehalose synthase
SCAB_RS39880	COG0366	Alpha amylase catalytic
SCAB_RS39905	COG0477	Major facilitator Superfamily
SCAB_RS39915	COG0395	ABC-type sugar transport system, permease component
SCAB_RS39920	COG1175	transmembrane transport
SCAB_RS39945	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SCAB_RS39950	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SCAB_RS39955	COG1968	undecaprenyl-diphosphatase activity
SCAB_RS39965	COG1113	amino acid transport
SCAB_RS39980	COG2066	Belongs to the glutaminase family
SCAB_RS39990	COG1686	Belongs to the peptidase S11 family
SCAB_RS39995	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
SCAB_RS40005	COG0366	Alpha amylase catalytic
SCAB_RS40010	COG2226	methyltransferase
SCAB_RS40020	COG3458	cephalosporin-C deacetylase activity
SCAB_RS40035	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SCAB_RS40045	COG2890	protein-(glutamine-N5) methyltransferase activity
SCAB_RS40050	COG1902	pentaerythritol trinitrate reductase activity
SCAB_RS40050	COG0446	pyridine nucleotide-disulphide oxidoreductase
SCAB_RS40060	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SCAB_RS40085	COG1461	Dihydroxyacetone kinase
SCAB_RS40090	COG2376	Dihydroxyacetone kinase
SCAB_RS40100	COG2197	response regulator
SCAB_RS40125	COG3321	synthase
SCAB_RS40125	COG0604	alcohol dehydrogenase
SCAB_RS40140	COG1250	3-hydroxyacyl-CoA dehydrogenase
SCAB_RS40160	COG1819	glycosyl
SCAB_RS40185	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
SCAB_RS40210	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
SCAB_RS40245	COG1132	(ABC) transporter
SCAB_RS40270	COG4585	Histidine kinase
SCAB_RS40275	COG2197	response regulator
SCAB_RS40290	COG2188	Transcriptional regulator
SCAB_RS40295	COG4214	carbohydrate transport
SCAB_RS40300	COG1129	ABC transporter
SCAB_RS40315	COG0179	Fumarylacetoacetate (FAA) hydrolase
SCAB_RS40320	COG4948	Mandelate Racemase Muconate Lactonizing
SCAB_RS40325	COG1028	Short-chain dehydrogenase reductase Sdr
SCAB_RS40340	COG3618	amidohydrolase
SCAB_RS40345	COG1122	ATPase activity
SCAB_RS40355	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
SCAB_RS40360	COG0310	cobalt ion transport
SCAB_RS40365	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
SCAB_RS40385	COG0640	Transcriptional regulator
SCAB_RS40400	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SCAB_RS40415	COG0019	diaminopimelate decarboxylase activity
SCAB_RS40435	COG1960	acyl-CoA dehydrogenase activity
SCAB_RS40440	COG3835	regulator
SCAB_RS40450	COG0443	Heat shock 70 kDa protein
SCAB_RS40455	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SCAB_RS40470	COG0542	response to heat
SCAB_RS40485	COG3634	alkyl hydroperoxide reductase activity
SCAB_RS40520	COG3507	Belongs to the glycosyl hydrolase 43 family
SCAB_RS40525	COG1609	Transcriptional regulator
SCAB_RS40540	COG0395	ABC-type sugar transport system, permease component
SCAB_RS40545	COG3250	beta-galactosidase activity
SCAB_RS40560	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SCAB_RS40565	COG2070	2-Nitropropane dioxygenase
SCAB_RS40580	COG2366	antibiotic biosynthetic process
SCAB_RS40585	COG0318	PFAM AMP-dependent synthetase and ligase
SCAB_RS40625	COG0738	Major facilitator superfamily
SCAB_RS40650	COG4191	Histidine kinase
SCAB_RS40680	COG3594	Acyltransferase
SCAB_RS40715	COG0702	epimerase
SCAB_RS40720	COG1846	Transcriptional regulator
SCAB_RS40725	COG2409	Drug exporters of the RND superfamily
SCAB_RS40730	COG0431	NADPH-dependent FMN reductase
SCAB_RS40735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SCAB_RS40740	COG0456	acetyltransferase
SCAB_RS40770	COG0346	lactoylglutathione lyase activity
SCAB_RS40775	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SCAB_RS40795	COG0583	DNA-binding transcription factor activity
SCAB_RS40800	COG0667	Aldo Keto reductase
SCAB_RS40820	COG0842	Transport permease protein
SCAB_RS40820	COG1131	(ABC) transporter
SCAB_RS40820	COG1716	ATPase activity
SCAB_RS40835	COG0698	ribose 5-phosphate isomerase
SCAB_RS40840	COG0640	Transcriptional regulator
SCAB_RS40860	COG1132	(ABC) transporter
SCAB_RS40865	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
SCAB_RS40880	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SCAB_RS40885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SCAB_RS40890	COG1120	ATPase activity
SCAB_RS40895	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SCAB_RS40900	COG3486	L-lysine 6-monooxygenase (NADPH) activity
SCAB_RS40920	COG2318	DinB family
SCAB_RS40925	COG1396	sequence-specific DNA binding
SCAB_RS40930	COG0740	serine-type endopeptidase activity
SCAB_RS40935	COG0740	serine-type endopeptidase activity
SCAB_RS40970	COG0328	RNA-DNA hybrid ribonuclease activity
SCAB_RS41005	COG0494	nUDIX hydrolase
SCAB_RS41020	COG0477	Major facilitator Superfamily
SCAB_RS41025	COG0667	Aldo Keto reductase
SCAB_RS41035	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SCAB_RS41085	COG2172	sigma factor antagonist activity
SCAB_RS41090	COG1366	Belongs to the anti-sigma-factor antagonist family
SCAB_RS41095	COG1366	Belongs to the anti-sigma-factor antagonist family
SCAB_RS41115	COG1191	sigma factor activity
SCAB_RS41145	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SCAB_RS41155	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SCAB_RS41160	COG0456	acetyltransferase
SCAB_RS41170	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SCAB_RS41175	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SCAB_RS41180	COG0019	diaminopimelate decarboxylase activity
SCAB_RS41190	COG2197	response regulator
SCAB_RS41195	COG4585	Histidine kinase
SCAB_RS41205	COG1131	(ABC) transporter
SCAB_RS41235	COG3851	Histidine kinase
SCAB_RS41240	COG2197	response regulator
SCAB_RS41250	COG2197	response regulator
SCAB_RS41255	COG2197	response regulator
SCAB_RS41285	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SCAB_RS41300	COG1959	2 iron, 2 sulfur cluster binding
SCAB_RS41315	COG0590	tRNA wobble adenosine to inosine editing
SCAB_RS41320	COG1028	Short-chain dehydrogenase reductase Sdr
SCAB_RS41345	COG0640	Transcriptional regulator
SCAB_RS41350	COG0346	lactoylglutathione lyase activity
SCAB_RS41360	COG1609	Transcriptional regulator
SCAB_RS41365	COG3507	Belongs to the glycosyl hydrolase 43 family
SCAB_RS41370	COG4172	Belongs to the ABC transporter superfamily
SCAB_RS41375	COG0444	Belongs to the ABC transporter superfamily
SCAB_RS41385	COG0747	negative chemotaxis
SCAB_RS41390	COG1609	Transcriptional regulator
SCAB_RS41400	COG3250	beta-galactosidase activity
SCAB_RS41405	COG2267	carboxylic ester hydrolase activity
SCAB_RS41410	COG2814	Major facilitator Superfamily
SCAB_RS41415	COG1609	Transcriptional regulator
SCAB_RS41450	COG1609	Transcriptional regulator
SCAB_RS41455	COG1175	transmembrane transport
SCAB_RS41470	COG3250	beta-galactosidase activity
SCAB_RS41475	COG3250	beta-galactosidase activity
SCAB_RS41500	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SCAB_RS41510	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SCAB_RS41540	COG0739	heme binding
SCAB_RS41560	COG1024	Enoyl-CoA hydratase
SCAB_RS41560	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SCAB_RS41600	COG0375	protein maturation
SCAB_RS41605	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SCAB_RS41610	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
SCAB_RS41625	COG0309	Hydrogenase expression formation protein (HypE)
SCAB_RS41635	COG4941	Belongs to the sigma-70 factor family
SCAB_RS41640	COG3795	YCII-related domain
SCAB_RS41645	COG5002	protein histidine kinase activity
SCAB_RS41645	COG2205	protein histidine kinase activity
SCAB_RS41645	COG0784	Response regulator, receiver
SCAB_RS41660	COG1191	sigma factor activity
SCAB_RS41695	COG1846	Transcriptional regulator
SCAB_RS41715	COG2226	methyltransferase
SCAB_RS41740	COG3293	Transposase
SCAB_RS41770	COG2045	Belongs to the ComB family
SCAB_RS41800	COG3655	Transcriptional regulator
SCAB_RS41815	COG3250	beta-galactosidase activity
SCAB_RS41820	COG0395	ABC-type sugar transport system, permease component
SCAB_RS41825	COG1175	transmembrane transport
SCAB_RS41835	COG1028	Short-chain dehydrogenase reductase Sdr
SCAB_RS41840	COG1802	Transcriptional regulator
SCAB_RS41845	COG4948	Mandelate Racemase Muconate Lactonizing
SCAB_RS41850	COG0800	Aldolase
SCAB_RS41860	COG3386	PFAM SMP-30 Gluconolaconase
SCAB_RS41865	COG0076	glutamate decarboxylase activity
SCAB_RS41870	COG1522	sequence-specific DNA binding
SCAB_RS41875	COG1278	Cold shock
SCAB_RS41880	COG0513	Belongs to the DEAD box helicase family
SCAB_RS41895	COG1278	Cold shock
SCAB_RS41900	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SCAB_RS41905	COG2072	flavoprotein involved in K transport
SCAB_RS41910	COG1028	Short-chain dehydrogenase reductase Sdr
SCAB_RS41915	COG1012	belongs to the aldehyde dehydrogenase family
SCAB_RS41935	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SCAB_RS41945	COG1522	sequence-specific DNA binding
SCAB_RS41965	COG0183	Belongs to the thiolase family
SCAB_RS41975	COG1250	3-hydroxyacyl-CoA dehydrogenase
SCAB_RS41980	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SCAB_RS42015	COG0179	Fumarylacetoacetate (FAA) hydrolase
SCAB_RS42020	COG0251	oxidation-reduction process
SCAB_RS42040	COG1028	Short-chain dehydrogenase reductase Sdr
SCAB_RS42065	COG1414	Transcriptional regulator
SCAB_RS42075	COG0833	amino acid
SCAB_RS42105	COG3693	PFAM glycoside hydrolase, family 10
SCAB_RS42125	COG1695	Transcriptional regulator
SCAB_RS42145	COG4585	Histidine kinase
SCAB_RS42150	COG2197	response regulator
SCAB_RS42165	COG1136	(ABC) transporter
SCAB_RS42190	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SCAB_RS42205	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SCAB_RS42230	COG0515	serine threonine protein kinase
SCAB_RS42260	COG1063	alcohol dehydrogenase
SCAB_RS42265	COG0179	Fumarylacetoacetate (FAA) hydrolase
SCAB_RS42270	COG1414	Transcriptional regulator
SCAB_RS42275	COG0129	dihydroxy-acid dehydratase activity
SCAB_RS42295	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
SCAB_RS42300	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
SCAB_RS42320	COG2319	Wd-40 repeat
SCAB_RS42320	COG4249	Peptidase C14 caspase catalytic subunit p20
SCAB_RS42325	COG0726	polysaccharide deacetylase
SCAB_RS42330	COG2197	response regulator
SCAB_RS42335	COG4585	Histidine kinase
SCAB_RS42340	COG2197	response regulator
SCAB_RS42345	COG4585	Histidine kinase
SCAB_RS42350	COG2409	Drug exporters of the RND superfamily
SCAB_RS42375	COG2080	2 iron, 2 sulfur cluster binding
SCAB_RS42380	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
SCAB_RS42385	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SCAB_RS42395	COG4221	oxidoreductase activity
SCAB_RS42400	COG1309	transcriptional regulator
SCAB_RS42410	COG1802	Transcriptional regulator
SCAB_RS42460	COG2197	response regulator
SCAB_RS42510	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SCAB_RS42515	COG0657	acetylesterase activity
SCAB_RS42520	COG0179	Fumarylacetoacetate (FAA) hydrolase
SCAB_RS42550	COG2223	nitrite transmembrane transporter activity
SCAB_RS42555	COG1349	DNA-binding transcription factor activity
SCAB_RS42575	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SCAB_RS42590	COG0028	Belongs to the TPP enzyme family
SCAB_RS42610	COG1028	Short-chain dehydrogenase reductase Sdr
SCAB_RS42615	COG1063	alcohol dehydrogenase
SCAB_RS42620	COG3618	amidohydrolase
SCAB_RS42635	COG0395	ABC-type sugar transport system, permease component
SCAB_RS42650	COG2186	Transcriptional regulator
SCAB_RS42655	COG1742	UPF0060 membrane protein
SCAB_RS42665	COG0745	RESPONSE REGULATOR receiver
SCAB_RS42725	COG1028	Short-chain dehydrogenase reductase Sdr
SCAB_RS42735	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SCAB_RS42745	COG1012	belongs to the aldehyde dehydrogenase family
SCAB_RS42750	COG3340	Belongs to the peptidase S51 family
SCAB_RS42760	COG0546	phosphoglycolate phosphatase activity
SCAB_RS42765	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SCAB_RS42775	COG3268	Saccharopine dehydrogenase
SCAB_RS42800	COG1960	acyl-CoA dehydrogenase activity
SCAB_RS42805	COG2130	NADP-dependent
SCAB_RS42820	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SCAB_RS42870	COG2311	Membrane
SCAB_RS42920	COG1733	regulation of RNA biosynthetic process
SCAB_RS42930	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SCAB_RS42965	COG1175	transmembrane transport
SCAB_RS42970	COG1653	transport
SCAB_RS42980	COG1472	Belongs to the glycosyl hydrolase 3 family
SCAB_RS43010	COG4565	transcriptional regulatory protein
SCAB_RS43015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SCAB_RS43020	COG1126	abc transporter atp-binding protein
SCAB_RS43025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SCAB_RS43030	COG0765	amino acid transport
SCAB_RS43035	COG0765	amino acid transport
SCAB_RS43040	COG1027	Aspartate ammonia-lyase
SCAB_RS43055	COG1136	(ABC) transporter
SCAB_RS43055	COG0577	efflux transmembrane transporter activity
SCAB_RS43060	COG1136	(ABC) transporter
SCAB_RS43060	COG0577	efflux transmembrane transporter activity
SCAB_RS43085	COG4733	cellulase activity
SCAB_RS43085	COG5297	Belongs to the glycosyl hydrolase family 6
SCAB_RS43090	COG5297	Belongs to the glycosyl hydrolase family 6
SCAB_RS43130	COG0402	S-adenosylhomocysteine deaminase activity
SCAB_RS43150	COG0477	Major facilitator Superfamily
SCAB_RS43165	COG2124	cytochrome p450
SCAB_RS43170	COG1012	belongs to the aldehyde dehydrogenase family
SCAB_RS43175	COG2124	cytochrome p450
SCAB_RS43205	COG1028	Short-chain dehydrogenase reductase Sdr
SCAB_RS43215	COG0179	Fumarylacetoacetate (FAA) hydrolase
SCAB_RS43220	COG0179	Fumarylacetoacetate (FAA) hydrolase
SCAB_RS43225	COG1028	Short-chain dehydrogenase reductase Sdr
SCAB_RS43230	COG1012	belongs to the aldehyde dehydrogenase family
SCAB_RS43245	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SCAB_RS43255	COG0438	transferase activity, transferring glycosyl groups
SCAB_RS43290	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SCAB_RS43305	COG0179	Fumarylacetoacetate (FAA) hydrolase
SCAB_RS43335	COG0179	Fumarylacetoacetate (FAA) hydrolase
SCAB_RS43340	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SCAB_RS43345	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SCAB_RS43415	COG0583	DNA-binding transcription factor activity
SCAB_RS43430	COG0583	DNA-binding transcription factor activity
SCAB_RS43435	COG2963	transposase activity
SCAB_RS43475	COG2801	Transposase and inactivated derivatives
SCAB_RS43500	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SCAB_RS43585	COG2070	2-Nitropropane dioxygenase
SCAB_RS43615	COG4585	Histidine kinase
SCAB_RS43625	COG1063	alcohol dehydrogenase
SCAB_RS43645	COG1028	Short-chain dehydrogenase reductase Sdr
SCAB_RS43720	COG1051	belongs to the nudix hydrolase family
SCAB_RS43740	COG2018	Roadblock/LC7 domain
SCAB_RS43770	COG2815	serine threonine protein kinase
SCAB_RS43770	COG0515	serine threonine protein kinase
SCAB_RS43775	COG0515	serine threonine protein kinase
SCAB_RS43775	COG2815	serine threonine protein kinase
SCAB_RS43880	COG2094	Belongs to the DNA glycosylase MPG family
SCAB_RS43895	COG3328	transposase activity
SCAB_RS43900	COG3328	transposase activity
SCAB_RS43910	COG3328	transposase activity