locus-tag	class	description
IPZ55_RS00010	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IPZ55_RS00015	COG1518	maintenance of DNA repeat elements
IPZ55_RS00075	COG1472	Belongs to the glycosyl hydrolase 3 family
IPZ55_RS00080	COG1874	Beta-galactosidase
IPZ55_RS00085	COG1609	Transcriptional regulator
IPZ55_RS00090	COG0395	ABC-type sugar transport system, permease component
IPZ55_RS00095	COG1175	transmembrane transport
IPZ55_RS00115	COG1028	Short-chain dehydrogenase reductase Sdr
IPZ55_RS00120	COG0477	Major facilitator Superfamily
IPZ55_RS00145	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IPZ55_RS00150	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
IPZ55_RS00155	COG2080	2 iron, 2 sulfur cluster binding
IPZ55_RS00165	COG2197	response regulator
IPZ55_RS00170	COG4585	Histidine kinase
IPZ55_RS00175	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IPZ55_RS00250	COG0446	pyridine nucleotide-disulphide oxidoreductase
IPZ55_RS00250	COG0404	The glycine cleavage system catalyzes the degradation of glycine
IPZ55_RS00300	COG4608	Belongs to the ABC transporter superfamily
IPZ55_RS00305	COG0444	Belongs to the ABC transporter superfamily
IPZ55_RS00310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IPZ55_RS00315	COG0601	transmembrane transport
IPZ55_RS00330	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IPZ55_RS00355	COG1793	dna ligase
IPZ55_RS00390	COG0277	FAD linked oxidase domain protein
IPZ55_RS00445	COG0318	PFAM AMP-dependent synthetase and ligase
IPZ55_RS00450	COG0589	response to stress
IPZ55_RS00455	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IPZ55_RS00460	COG2813	Specifically methylates the guanine in position
IPZ55_RS00470	COG2356	endonuclease I
IPZ55_RS00500	COG2084	Dehydrogenase
IPZ55_RS00515	COG2267	carboxylic ester hydrolase activity
IPZ55_RS00535	COG1007	ATP synthesis coupled electron transport
IPZ55_RS00540	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IPZ55_RS00545	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IPZ55_RS00550	COG0713	ATP synthesis coupled electron transport
IPZ55_RS00560	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
IPZ55_RS00570	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IPZ55_RS00590	COG1902	pentaerythritol trinitrate reductase activity
IPZ55_RS00590	COG0446	pyridine nucleotide-disulphide oxidoreductase
IPZ55_RS00600	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IPZ55_RS00635	COG0475	glutathione-regulated potassium exporter activity
IPZ55_RS00655	COG2197	response regulator
IPZ55_RS00665	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IPZ55_RS00680	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IPZ55_RS00690	COG3268	Saccharopine dehydrogenase
IPZ55_RS00715	COG0477	Major facilitator Superfamily
IPZ55_RS00730	COG0328	RNA-DNA hybrid ribonuclease activity
IPZ55_RS00735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IPZ55_RS00740	COG0431	NADPH-dependent FMN reductase
IPZ55_RS00770	COG1595	DNA-templated transcription, initiation
IPZ55_RS00795	COG0667	Aldo Keto reductase
IPZ55_RS00825	COG1028	Short-chain dehydrogenase reductase Sdr
IPZ55_RS00830	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IPZ55_RS00835	COG1131	(ABC) transporter
IPZ55_RS00855	COG0326	Molecular chaperone. Has ATPase activity
IPZ55_RS00875	COG0702	epimerase
IPZ55_RS00885	COG0346	lactoylglutathione lyase activity
IPZ55_RS00890	COG0640	Transcriptional regulator
IPZ55_RS00905	COG1120	ATPase activity
IPZ55_RS00925	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IPZ55_RS00935	COG1960	acyl-CoA dehydrogenase activity
IPZ55_RS00945	COG1250	3-hydroxyacyl-CoA dehydrogenase
IPZ55_RS00955	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IPZ55_RS00965	COG3547	Transposase (IS116 IS110 IS902 family)
IPZ55_RS00975	COG1349	DNA-binding transcription factor activity
IPZ55_RS00985	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
IPZ55_RS00985	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IPZ55_RS00985	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IPZ55_RS00990	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IPZ55_RS00990	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IPZ55_RS00995	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IPZ55_RS01020	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IPZ55_RS01050	COG1695	Transcriptional regulator
IPZ55_RS01075	COG1028	Short-chain dehydrogenase reductase Sdr
IPZ55_RS01090	COG0513	Belongs to the DEAD box helicase family
IPZ55_RS01100	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IPZ55_RS01115	COG0633	Ferredoxin
IPZ55_RS01115	COG3217	Mosc domain protein beta barrel domain protein
IPZ55_RS01135	COG1349	DNA-binding transcription factor activity
IPZ55_RS01155	COG1940	carbohydrate kinase activity
IPZ55_RS01165	COG2223	nitrite transmembrane transporter activity
IPZ55_RS01195	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IPZ55_RS01230	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
IPZ55_RS01270	COG0584	glycerophosphoryl diester phosphodiesterase
IPZ55_RS01285	COG1846	Transcriptional regulator
IPZ55_RS01305	COG0671	phosphoesterase, PA-phosphatase related
IPZ55_RS01335	COG2233	PERMEase
IPZ55_RS01340	COG0640	Transcriptional regulator
IPZ55_RS01345	COG1902	pentaerythritol trinitrate reductase activity
IPZ55_RS01360	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IPZ55_RS01375	COG2706	6-phosphogluconolactonase activity
IPZ55_RS01390	COG0071	Belongs to the small heat shock protein (HSP20) family
IPZ55_RS01395	COG0076	glutamate decarboxylase activity
IPZ55_RS01400	COG0243	molybdopterin cofactor binding
IPZ55_RS01410	COG0314	molybdopterin synthase activity
IPZ55_RS01415	COG0303	'Molybdopterin
IPZ55_RS01420	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IPZ55_RS01440	COG0583	DNA-binding transcription factor activity
IPZ55_RS01465	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IPZ55_RS01485	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IPZ55_RS01490	COG1120	ATPase activity
IPZ55_RS01495	COG2207	Transcriptional regulator
IPZ55_RS01500	COG2814	Major facilitator Superfamily
IPZ55_RS01525	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IPZ55_RS01540	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IPZ55_RS01560	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IPZ55_RS01580	COG0477	Major facilitator Superfamily
IPZ55_RS01585	COG1309	transcriptional regulator
IPZ55_RS01595	COG1472	Belongs to the glycosyl hydrolase 3 family
IPZ55_RS01605	COG1175	transmembrane transport
IPZ55_RS01615	COG1609	Transcriptional regulator
IPZ55_RS01620	COG0432	Pfam Uncharacterised protein family UPF0047
IPZ55_RS01625	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IPZ55_RS01630	COG1116	anion transmembrane transporter activity
IPZ55_RS01640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IPZ55_RS01650	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IPZ55_RS01655	COG1132	(ABC) transporter
IPZ55_RS01675	COG1132	(ABC) transporter
IPZ55_RS01680	COG1132	(ABC) transporter
IPZ55_RS01695	COG1946	Acyl-CoA thioesterase
IPZ55_RS01710	COG2018	Roadblock/LC7 domain
IPZ55_RS01755	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IPZ55_RS01780	COG1070	Carbohydrate kinase
IPZ55_RS01800	COG2124	cytochrome p450
IPZ55_RS01805	COG2130	NADP-dependent
IPZ55_RS01810	COG1233	COG1233 Phytoene dehydrogenase and related
IPZ55_RS01880	COG0477	Major facilitator Superfamily
IPZ55_RS01885	COG0183	Belongs to the thiolase family
IPZ55_RS01890	COG0583	DNA-binding transcription factor activity
IPZ55_RS01895	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IPZ55_RS01900	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IPZ55_RS01905	COG1250	3-hydroxyacyl-CoA dehydrogenase
IPZ55_RS01910	COG1960	acyl-CoA dehydrogenase activity
IPZ55_RS01915	COG2391	methyltransferase activity
IPZ55_RS01960	COG0740	serine-type endopeptidase activity
IPZ55_RS01965	COG0740	serine-type endopeptidase activity
IPZ55_RS02000	COG4521	taurine ABC transporter
IPZ55_RS02005	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IPZ55_RS02025	COG3959	Transketolase, thiamine diphosphate binding domain
IPZ55_RS02030	COG3958	Transketolase
IPZ55_RS02100	COG2755	lipolytic protein G-D-S-L family
IPZ55_RS02105	COG2365	Tyrosine phosphatase family
IPZ55_RS02135	COG1657	PFAM Prenyltransferase squalene oxidase
IPZ55_RS02145	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
IPZ55_RS02155	COG1562	ergosterol biosynthetic process
IPZ55_RS02160	COG1388	LysM domain
IPZ55_RS02160	COG1134	teichoic acid transport
IPZ55_RS02185	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IPZ55_RS02200	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
IPZ55_RS02215	COG1024	Enoyl-CoA hydratase
IPZ55_RS02230	COG2183	response to ionizing radiation
IPZ55_RS02245	COG1802	Transcriptional regulator
IPZ55_RS02250	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IPZ55_RS02255	COG0402	S-adenosylhomocysteine deaminase activity
IPZ55_RS02280	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IPZ55_RS02285	COG0789	Transcriptional regulator
IPZ55_RS02290	COG1250	3-hydroxyacyl-CoA dehydrogenase
IPZ55_RS02290	COG1024	Enoyl-CoA hydratase
IPZ55_RS02295	COG0183	Belongs to the thiolase family
IPZ55_RS02305	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IPZ55_RS02310	COG1683	Conserved Protein
IPZ55_RS02315	COG1515	deoxyribonuclease V activity
IPZ55_RS02345	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IPZ55_RS02355	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IPZ55_RS02355	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IPZ55_RS02365	COG0488	(ABC) transporter
IPZ55_RS02420	COG0254	rRNA binding
IPZ55_RS02440	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
IPZ55_RS02480	COG1793	dna ligase
IPZ55_RS02485	COG1024	Enoyl-CoA hydratase
IPZ55_RS02565	COG1846	Transcriptional regulator
IPZ55_RS02625	COG1012	belongs to the aldehyde dehydrogenase family
IPZ55_RS02645	COG2814	Major facilitator Superfamily
IPZ55_RS02650	COG2259	Doxx family
IPZ55_RS02660	COG1869	D-ribose catabolic process
IPZ55_RS02665	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IPZ55_RS02670	COG1172	Belongs to the binding-protein-dependent transport system permease family
IPZ55_RS02675	COG1129	ABC transporter
IPZ55_RS02680	COG1609	Transcriptional regulator
IPZ55_RS02700	COG1295	ribonuclease BN
IPZ55_RS02765	COG0673	inositol 2-dehydrogenase activity
IPZ55_RS02775	COG1172	Belongs to the binding-protein-dependent transport system permease family
IPZ55_RS02780	COG1129	ABC transporter
IPZ55_RS02785	COG1940	carbohydrate kinase activity
IPZ55_RS02790	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IPZ55_RS02805	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IPZ55_RS02815	COG0583	DNA-binding transcription factor activity
IPZ55_RS02820	COG1115	amino acid carrier protein
IPZ55_RS02835	COG2826	transposase and inactivated derivatives, IS30 family
IPZ55_RS02850	COG2154	pterin-4-alpha-carbinolamine dehydratase
IPZ55_RS02880	COG1140	nitrate reductase beta subunit
IPZ55_RS02940	COG0693	protein deglycase activity
IPZ55_RS02950	COG1597	lipid kinase activity
IPZ55_RS02955	COG4106	trans-aconitate 2-methyltransferase activity
IPZ55_RS02970	COG3226	Transcriptional regulator
IPZ55_RS02980	COG0604	alcohol dehydrogenase
IPZ55_RS02995	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IPZ55_RS03015	COG1619	proteins homologs of microcin C7 resistance protein MccF
IPZ55_RS03025	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IPZ55_RS03090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPZ55_RS03095	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPZ55_RS03100	COG1120	ATPase activity
IPZ55_RS03105	COG1250	3-hydroxyacyl-CoA dehydrogenase
IPZ55_RS03115	COG0604	alcohol dehydrogenase
IPZ55_RS03120	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IPZ55_RS03120	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IPZ55_RS03125	COG2301	Belongs to the HpcH HpaI aldolase family
IPZ55_RS03140	COG0688	phosphatidylethanolamine metabolic process
IPZ55_RS03150	COG1929	Belongs to the glycerate kinase type-1 family
IPZ55_RS03155	COG0488	(ABC) transporter
IPZ55_RS03165	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IPZ55_RS03170	COG0702	epimerase
IPZ55_RS03175	COG1028	Short-chain dehydrogenase reductase Sdr
IPZ55_RS03185	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
IPZ55_RS03210	COG0159	tryptophan synthase activity
IPZ55_RS03225	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
IPZ55_RS03240	COG0483	inositol monophosphate 1-phosphatase activity
IPZ55_RS03250	COG0095	Lipoate-protein ligase
IPZ55_RS03270	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IPZ55_RS03295	COG0405	Gamma-glutamyltransferase
IPZ55_RS03325	COG0765	amino acid transport
IPZ55_RS03330	COG0765	amino acid transport
IPZ55_RS03335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IPZ55_RS03340	COG1126	abc transporter atp-binding protein
IPZ55_RS03380	COG1228	amidohydrolase
IPZ55_RS03385	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IPZ55_RS03400	COG1960	acyl-CoA dehydrogenase activity
IPZ55_RS03430	COG2133	pyrroloquinoline quinone binding
IPZ55_RS03430	COG5183	chlorophyll binding
IPZ55_RS03435	COG1132	(ABC) transporter
IPZ55_RS03440	COG1132	(ABC) transporter
IPZ55_RS03445	COG1120	ATPase activity
IPZ55_RS03450	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPZ55_RS03455	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPZ55_RS03460	COG2375	cellular response to nickel ion
IPZ55_RS03465	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IPZ55_RS03470	COG2207	Transcriptional regulator
IPZ55_RS03500	COG2197	response regulator
IPZ55_RS03510	COG0464	growth
IPZ55_RS03595	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IPZ55_RS03605	COG1940	carbohydrate kinase activity
IPZ55_RS03615	COG1172	Belongs to the binding-protein-dependent transport system permease family
IPZ55_RS03625	COG2188	Transcriptional regulator
IPZ55_RS03630	COG0673	inositol 2-dehydrogenase activity
IPZ55_RS03645	COG2197	response regulator
IPZ55_RS03650	COG4585	Histidine kinase
IPZ55_RS03665	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IPZ55_RS03670	COG1414	Transcriptional regulator
IPZ55_RS03685	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IPZ55_RS03690	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
IPZ55_RS03695	COG2080	2 iron, 2 sulfur cluster binding
IPZ55_RS03700	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IPZ55_RS03715	COG4941	Belongs to the sigma-70 factor family
IPZ55_RS03720	COG3795	YCII-related domain
IPZ55_RS03725	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IPZ55_RS03750	COG1609	Transcriptional regulator
IPZ55_RS03800	COG2233	PERMEase
IPZ55_RS03815	COG2351	hydroxyisourate hydrolase activity
IPZ55_RS03835	COG3622	Belongs to the hyi family
IPZ55_RS03840	COG2084	Dehydrogenase
IPZ55_RS03845	COG0753	catalase activity
IPZ55_RS03850	COG3960	tartronate-semialdehyde synthase activity
IPZ55_RS03860	COG0318	PFAM AMP-dependent synthetase and ligase
IPZ55_RS03865	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IPZ55_RS03870	COG2197	response regulator
IPZ55_RS03880	COG1309	transcriptional regulator
IPZ55_RS03920	COG2252	PERMEase
IPZ55_RS03925	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IPZ55_RS03940	COG3835	regulator
IPZ55_RS03945	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
IPZ55_RS03955	COG1802	Transcriptional regulator
IPZ55_RS03970	COG1028	Short-chain dehydrogenase reductase Sdr
IPZ55_RS03985	COG0028	Belongs to the TPP enzyme family
IPZ55_RS04005	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IPZ55_RS04010	COG1162	GTPase activity
IPZ55_RS04020	COG2365	Tyrosine phosphatase family
IPZ55_RS04060	COG1595	DNA-templated transcription, initiation
IPZ55_RS04080	COG0702	epimerase
IPZ55_RS04085	COG1846	Transcriptional regulator
IPZ55_RS04090	COG2409	Drug exporters of the RND superfamily
IPZ55_RS04100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPZ55_RS04105	COG1120	ATPase activity
IPZ55_RS04115	COG2255	four-way junction helicase activity
IPZ55_RS04140	COG2040	homocysteine
IPZ55_RS04160	COG1960	acyl-CoA dehydrogenase activity
IPZ55_RS04165	COG0604	alcohol dehydrogenase
IPZ55_RS04170	COG1309	transcriptional regulator
IPZ55_RS04190	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IPZ55_RS04200	COG0175	sulfate reduction
IPZ55_RS04205	COG0529	Catalyzes the synthesis of activated sulfate
IPZ55_RS04230	COG1116	anion transmembrane transporter activity
IPZ55_RS04235	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IPZ55_RS04250	COG0386	Belongs to the glutathione peroxidase family
IPZ55_RS04285	COG2176	DNA-directed DNA polymerase activity
IPZ55_RS04285	COG5002	protein histidine kinase activity
IPZ55_RS04350	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IPZ55_RS04355	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IPZ55_RS04375	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IPZ55_RS04380	COG1595	DNA-templated transcription, initiation
IPZ55_RS04395	COG0726	polysaccharide deacetylase
IPZ55_RS04405	COG3220	belongs to the UPF0276 family
IPZ55_RS04415	COG3253	May function as heme-dependent peroxidase
IPZ55_RS04420	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
IPZ55_RS04435	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IPZ55_RS04455	COG0183	Belongs to the thiolase family
IPZ55_RS04460	COG1250	3-hydroxyacyl-CoA dehydrogenase
IPZ55_RS04460	COG1024	Enoyl-CoA hydratase
IPZ55_RS04480	COG0531	amino acid
IPZ55_RS04485	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IPZ55_RS04490	COG4214	carbohydrate transport
IPZ55_RS04500	COG4213	ABC transporter substrate-binding protein
IPZ55_RS04510	COG0395	ABC-type sugar transport system, permease component
IPZ55_RS04515	COG1175	transmembrane transport
IPZ55_RS04520	COG1653	transport
IPZ55_RS04525	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IPZ55_RS04550	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IPZ55_RS04570	COG1120	ATPase activity
IPZ55_RS04575	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPZ55_RS04580	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IPZ55_RS04610	COG2235	arginine
IPZ55_RS04615	COG1320	monovalent cation:proton antiporter activity
IPZ55_RS04630	COG0651	ATP synthesis coupled electron transport
IPZ55_RS04640	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IPZ55_RS04640	COG2111	Na H antiporter
IPZ55_RS04650	COG2124	cytochrome p450
IPZ55_RS04680	COG0531	amino acid
IPZ55_RS04685	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IPZ55_RS04690	COG2235	arginine
IPZ55_RS04710	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IPZ55_RS04745	COG1799	cell septum assembly
IPZ55_RS04755	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
IPZ55_RS04770	COG1556	Lactate utilization protein
IPZ55_RS04775	COG1139	Iron-sulfur cluster binding protein
IPZ55_RS04780	COG0247	lactate metabolic process
IPZ55_RS04785	COG1620	l-lactate permease
IPZ55_RS04795	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
IPZ55_RS04835	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IPZ55_RS04845	COG0267	Belongs to the bacterial ribosomal protein bL33 family
IPZ55_RS04860	COG1120	ATPase activity
IPZ55_RS04865	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPZ55_RS04870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPZ55_RS04880	COG1733	regulation of RNA biosynthetic process
IPZ55_RS04900	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IPZ55_RS04905	COG0601	transmembrane transport
IPZ55_RS04915	COG0747	negative chemotaxis
IPZ55_RS04925	COG1309	transcriptional regulator
IPZ55_RS04940	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IPZ55_RS04955	COG2936	dipeptidyl-peptidase activity
IPZ55_RS04980	COG3540	Alkaline phosphatase
IPZ55_RS04990	COG2050	protein possibly involved in aromatic compounds catabolism
IPZ55_RS05005	COG0789	Transcriptional regulator
IPZ55_RS05015	COG0640	Transcriptional regulator
IPZ55_RS05035	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IPZ55_RS05080	COG0438	transferase activity, transferring glycosyl groups
IPZ55_RS05085	COG3226	Transcriptional regulator
IPZ55_RS05090	COG0738	Major facilitator superfamily
IPZ55_RS05105	COG4213	ABC transporter substrate-binding protein
IPZ55_RS05110	COG1172	Belongs to the binding-protein-dependent transport system permease family
IPZ55_RS05115	COG1172	Belongs to the binding-protein-dependent transport system permease family
IPZ55_RS05120	COG1129	ABC transporter
IPZ55_RS05125	COG1846	Transcriptional regulator
IPZ55_RS05125	COG1940	carbohydrate kinase activity
IPZ55_RS05130	COG0252	asparaginase activity
IPZ55_RS05140	COG1028	Short-chain dehydrogenase reductase Sdr
IPZ55_RS05160	COG1028	Short-chain dehydrogenase reductase Sdr
IPZ55_RS05175	COG1028	Short-chain dehydrogenase reductase Sdr
IPZ55_RS05210	COG0473	3-isopropylmalate dehydrogenase activity
IPZ55_RS05225	COG0656	L-ascorbic acid biosynthetic process
IPZ55_RS05260	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IPZ55_RS05285	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IPZ55_RS05295	COG1127	ABC transporter
IPZ55_RS05340	COG0583	DNA-binding transcription factor activity
IPZ55_RS05350	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
IPZ55_RS05365	COG4221	oxidoreductase activity
IPZ55_RS05370	COG0300	oxidoreductase activity
IPZ55_RS05435	COG2233	PERMEase
IPZ55_RS05440	COG0402	S-adenosylhomocysteine deaminase activity
IPZ55_RS05455	COG0559	Belongs to the binding-protein-dependent transport system permease family
IPZ55_RS05490	COG0395	ABC-type sugar transport system, permease component
IPZ55_RS05495	COG1063	alcohol dehydrogenase
IPZ55_RS05510	COG0438	transferase activity, transferring glycosyl groups
IPZ55_RS05515	COG2197	response regulator
IPZ55_RS05525	COG1136	(ABC) transporter
IPZ55_RS05535	COG2197	response regulator
IPZ55_RS05545	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IPZ55_RS05555	COG3251	PFAM MbtH domain protein
IPZ55_RS05565	COG2175	clavaminate synthase activity
IPZ55_RS05665	COG1201	RNA secondary structure unwinding
IPZ55_RS05670	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IPZ55_RS05675	COG0531	amino acid
IPZ55_RS05680	COG0569	domain protein
IPZ55_RS05710	COG1136	(ABC) transporter
IPZ55_RS05710	COG4591	ABC-type transport system involved in lipoprotein release permease component
IPZ55_RS05730	COG0756	dUTP diphosphatase activity
IPZ55_RS05755	COG2205	protein histidine kinase activity
IPZ55_RS05760	COG0745	RESPONSE REGULATOR receiver
IPZ55_RS05770	COG0483	inositol monophosphate 1-phosphatase activity
IPZ55_RS05775	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
IPZ55_RS05825	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IPZ55_RS05830	COG1802	Transcriptional regulator
IPZ55_RS05845	COG0612	Peptidase, M16
IPZ55_RS05850	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IPZ55_RS05860	COG0366	Alpha amylase catalytic
IPZ55_RS05865	COG0395	ABC-type sugar transport system, permease component
IPZ55_RS05870	COG1175	transmembrane transport
IPZ55_RS05875	COG1653	transport
IPZ55_RS05890	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IPZ55_RS05910	COG0187	DNA topoisomerase II activity
IPZ55_RS05925	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IPZ55_RS05930	COG1802	Transcriptional regulator
IPZ55_RS05965	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IPZ55_RS05980	COG0588	phosphoglycerate mutase activity
IPZ55_RS06000	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IPZ55_RS06005	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IPZ55_RS06010	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IPZ55_RS06050	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IPZ55_RS06060	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IPZ55_RS06065	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IPZ55_RS06075	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IPZ55_RS06095	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IPZ55_RS06105	COG2205	protein histidine kinase activity
IPZ55_RS06110	COG0745	RESPONSE REGULATOR receiver
IPZ55_RS06115	COG1126	abc transporter atp-binding protein
IPZ55_RS06120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IPZ55_RS06125	COG0765	amino acid transport
IPZ55_RS06130	COG0765	amino acid transport
IPZ55_RS06135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IPZ55_RS06145	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IPZ55_RS06150	COG2137	regulation of response to DNA damage stimulus
IPZ55_RS06155	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IPZ55_RS06180	COG0628	permease
IPZ55_RS06205	COG1201	RNA secondary structure unwinding
IPZ55_RS06210	COG0596	Alpha beta hydrolase
IPZ55_RS06230	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IPZ55_RS06240	COG0783	Belongs to the Dps family
IPZ55_RS06245	COG1396	sequence-specific DNA binding
IPZ55_RS06250	COG1058	Belongs to the CinA family
IPZ55_RS06250	COG1546	Belongs to the CinA family
IPZ55_RS06260	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IPZ55_RS06270	COG1674	ftsk spoiiie
IPZ55_RS06280	COG2205	protein histidine kinase activity
IPZ55_RS06280	COG4999	Histidine kinase
IPZ55_RS06280	COG3437	response regulator, receiver
IPZ55_RS06280	COG3850	Histidine kinase
IPZ55_RS06315	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IPZ55_RS06320	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IPZ55_RS06325	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
IPZ55_RS06345	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
IPZ55_RS06350	COG0612	Peptidase, M16
IPZ55_RS06355	COG1185	polyribonucleotide nucleotidyltransferase activity
IPZ55_RS06360	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IPZ55_RS06370	COG0455	bacterial-type flagellum organization
IPZ55_RS06375	COG0747	negative chemotaxis
IPZ55_RS06380	COG0601	transmembrane transport
IPZ55_RS06385	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IPZ55_RS06390	COG0444	Belongs to the ABC transporter superfamily
IPZ55_RS06395	COG4608	Belongs to the ABC transporter superfamily
IPZ55_RS06400	COG1357	PFAM Pentapeptide repeats (8 copies)
IPZ55_RS06415	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IPZ55_RS06420	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IPZ55_RS06430	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IPZ55_RS06445	COG0779	Required for maturation of 30S ribosomal subunits
IPZ55_RS06465	COG0442	prolyl-tRNA aminoacylation
IPZ55_RS06485	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IPZ55_RS06490	COG0601	transmembrane transport
IPZ55_RS06495	COG0747	negative chemotaxis
IPZ55_RS06510	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IPZ55_RS06515	COG0750	zinc metalloprotease
IPZ55_RS06520	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
IPZ55_RS06525	COG1940	carbohydrate kinase activity
IPZ55_RS06530	COG1012	belongs to the aldehyde dehydrogenase family
IPZ55_RS06570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IPZ55_RS06575	COG1177	transmembrane transport
IPZ55_RS06580	COG1176	ABC-type spermidine putrescine transport system, permease component I
IPZ55_RS06585	COG3842	ATPase activity
IPZ55_RS06595	COG1012	belongs to the aldehyde dehydrogenase family
IPZ55_RS06610	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IPZ55_RS06630	COG1012	belongs to the aldehyde dehydrogenase family
IPZ55_RS06640	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IPZ55_RS06665	COG3842	ATPase activity
IPZ55_RS06670	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IPZ55_RS06680	COG0820	rRNA (adenine-C2-)-methyltransferase activity
IPZ55_RS06685	COG0575	Belongs to the CDS family
IPZ55_RS06690	COG0233	cytoplasmic translational termination
IPZ55_RS06695	COG0528	UMP kinase activity
IPZ55_RS06700	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IPZ55_RS06705	COG0052	Belongs to the universal ribosomal protein uS2 family
IPZ55_RS06720	COG1191	sigma factor activity
IPZ55_RS06805	COG0792	nuclease activity
IPZ55_RS06820	COG0681	Belongs to the peptidase S26 family
IPZ55_RS06825	COG0681	Belongs to the peptidase S26 family
IPZ55_RS06830	COG0681	Belongs to the peptidase S26 family
IPZ55_RS06835	COG0681	Belongs to the peptidase S26 family
IPZ55_RS06840	COG0335	large ribosomal subunit rRNA binding
IPZ55_RS06845	COG0336	Belongs to the RNA methyltransferase TrmD family
IPZ55_RS06850	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IPZ55_RS06855	COG1837	Belongs to the UPF0109 family
IPZ55_RS06860	COG0228	four-way junction DNA binding
IPZ55_RS06875	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IPZ55_RS06885	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
IPZ55_RS06915	COG0477	Major facilitator Superfamily
IPZ55_RS06920	COG1196	nuclear chromosome segregation
IPZ55_RS06930	COG1254	Belongs to the acylphosphatase family
IPZ55_RS06935	COG2340	Cysteine-rich secretory protein family
IPZ55_RS06965	COG2188	Transcriptional regulator
IPZ55_RS06980	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IPZ55_RS06985	COG0571	ribonuclease III activity
IPZ55_RS06990	COG0333	Belongs to the bacterial ribosomal protein bL32 family
IPZ55_RS07005	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IPZ55_RS07010	COG0742	ribosomal rna small subunit methyltransferase
IPZ55_RS07020	COG1461	Dihydroxyacetone kinase
IPZ55_RS07025	COG0227	Belongs to the bacterial ribosomal protein bL28 family
IPZ55_RS07030	COG0351	phosphomethylpyrimidine kinase
IPZ55_RS07050	COG1181	Belongs to the D-alanine--D-alanine ligase family
IPZ55_RS07055	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
IPZ55_RS07065	COG1920	GTP binding
IPZ55_RS07075	COG0776	regulation of translation
IPZ55_RS07085	COG0066	3-isopropylmalate dehydratase activity
IPZ55_RS07090	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IPZ55_RS07095	COG1414	Transcriptional regulator
IPZ55_RS07140	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IPZ55_RS07145	COG0179	Fumarylacetoacetate (FAA) hydrolase
IPZ55_RS07160	COG2018	Roadblock/LC7 domain
IPZ55_RS07180	COG2018	Roadblock/LC7 domain
IPZ55_RS07200	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IPZ55_RS07210	COG2353	YceI-like domain
IPZ55_RS07250	COG0789	Transcriptional regulator
IPZ55_RS07270	COG4221	oxidoreductase activity
IPZ55_RS07305	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IPZ55_RS07310	COG0477	Major facilitator Superfamily
IPZ55_RS07315	COG2957	Belongs to the agmatine deiminase family
IPZ55_RS07320	COG0804	urea catabolic process
IPZ55_RS07325	COG0832	Belongs to the urease beta subunit family
IPZ55_RS07325	COG0831	urea catabolic process
IPZ55_RS07330	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IPZ55_RS07335	COG0473	3-isopropylmalate dehydrogenase activity
IPZ55_RS07360	COG1012	belongs to the aldehyde dehydrogenase family
IPZ55_RS07365	COG0506	proline dehydrogenase activity
IPZ55_RS07370	COG3835	regulator
IPZ55_RS07390	COG2890	protein-(glutamine-N5) methyltransferase activity
IPZ55_RS07400	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IPZ55_RS07405	COG0440	acetolactate synthase activity
IPZ55_RS07425	COG0667	Aldo Keto reductase
IPZ55_RS07430	COG2133	pyrroloquinoline quinone binding
IPZ55_RS07450	COG2197	response regulator
IPZ55_RS07470	COG2409	Drug exporters of the RND superfamily
IPZ55_RS07475	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IPZ55_RS07485	COG0154	amidase activity
IPZ55_RS07490	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IPZ55_RS07500	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IPZ55_RS07510	COG4221	oxidoreductase activity
IPZ55_RS07530	COG0482	sulfurtransferase activity
IPZ55_RS07555	COG2860	membrane
IPZ55_RS07560	COG4608	Belongs to the ABC transporter superfamily
IPZ55_RS07565	COG0444	Belongs to the ABC transporter superfamily
IPZ55_RS07570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IPZ55_RS07575	COG0601	transmembrane transport
IPZ55_RS07580	COG0747	negative chemotaxis
IPZ55_RS07600	COG0404	The glycine cleavage system catalyzes the degradation of glycine
IPZ55_RS07605	COG0509	glycine decarboxylation via glycine cleavage system
IPZ55_RS07610	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IPZ55_RS07615	COG1760	l-serine dehydratase
IPZ55_RS07630	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
IPZ55_RS07635	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
IPZ55_RS07640	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
IPZ55_RS07655	COG0477	Major facilitator Superfamily
IPZ55_RS07670	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IPZ55_RS07695	COG2085	NADP oxidoreductase coenzyme F420-dependent
IPZ55_RS07720	COG1376	ErfK ybiS ycfS ynhG family protein
IPZ55_RS07745	COG1132	(ABC) transporter
IPZ55_RS07750	COG1132	(ABC) transporter
IPZ55_RS07760	COG1733	regulation of RNA biosynthetic process
IPZ55_RS07780	COG0366	Alpha amylase catalytic
IPZ55_RS07785	COG0366	Alpha amylase catalytic
IPZ55_RS07790	COG3281	Trehalose synthase
IPZ55_RS07795	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IPZ55_RS07810	COG1119	ATPase activity
IPZ55_RS07815	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IPZ55_RS07830	COG1301	dicarboxylic acid transport
IPZ55_RS07835	COG3290	protein histidine kinase activity
IPZ55_RS07840	COG4565	transcriptional regulatory protein
IPZ55_RS07845	COG0205	6-phosphofructokinase activity
IPZ55_RS07850	COG0280	phosphate acetyltransferase
IPZ55_RS07850	COG0857	belongs to the CobB CobQ family
IPZ55_RS07855	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IPZ55_RS07895	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IPZ55_RS07895	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IPZ55_RS07970	COG1335	isochorismatase
IPZ55_RS08005	COG0829	nickel cation binding
IPZ55_RS08010	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
IPZ55_RS08015	COG0830	nickel cation binding
IPZ55_RS08020	COG0804	urea catabolic process
IPZ55_RS08025	COG0831	urea catabolic process
IPZ55_RS08025	COG0832	Belongs to the urease beta subunit family
IPZ55_RS08035	COG0831	urea catabolic process
IPZ55_RS08045	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IPZ55_RS08050	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IPZ55_RS08065	COG0183	Belongs to the thiolase family
IPZ55_RS08085	COG1131	(ABC) transporter
IPZ55_RS08120	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
IPZ55_RS08135	COG1250	3-hydroxyacyl-CoA dehydrogenase
IPZ55_RS08150	COG4585	Histidine kinase
IPZ55_RS08155	COG2197	response regulator
IPZ55_RS08175	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IPZ55_RS08180	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IPZ55_RS08185	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IPZ55_RS08190	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IPZ55_RS08195	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IPZ55_RS08200	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IPZ55_RS08205	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IPZ55_RS08220	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IPZ55_RS08225	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IPZ55_RS08235	COG2890	protein-(glutamine-N5) methyltransferase activity
IPZ55_RS08240	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IPZ55_RS08245	COG0254	rRNA binding
IPZ55_RS08250	COG1316	TRANSCRIPTIONal
IPZ55_RS08260	COG0083	homoserine kinase activity
IPZ55_RS08265	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IPZ55_RS08270	COG0460	homoserine dehydrogenase
IPZ55_RS08275	COG0019	diaminopimelate decarboxylase activity
IPZ55_RS08280	COG0018	arginyl-trna synthetase
IPZ55_RS08305	COG1012	belongs to the aldehyde dehydrogenase family
IPZ55_RS08315	COG1191	sigma factor activity
IPZ55_RS08320	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IPZ55_RS08320	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IPZ55_RS08330	COG2267	carboxylic ester hydrolase activity
IPZ55_RS08350	COG0772	Belongs to the SEDS family
IPZ55_RS08425	COG0726	polysaccharide deacetylase
IPZ55_RS08430	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IPZ55_RS08435	COG0477	Major facilitator Superfamily
IPZ55_RS08450	COG1595	DNA-templated transcription, initiation
IPZ55_RS08460	COG1131	(ABC) transporter
IPZ55_RS08480	COG0745	RESPONSE REGULATOR receiver
IPZ55_RS08485	COG2205	protein histidine kinase activity
IPZ55_RS08490	COG0508	dehydrogenase complex catalyzes the overall conversion of
IPZ55_RS08490	COG0567	Dehydrogenase, E1 component
IPZ55_RS08520	COG2255	four-way junction helicase activity
IPZ55_RS08565	COG0604	alcohol dehydrogenase
IPZ55_RS08570	COG0281	malic enzyme
IPZ55_RS08585	COG1126	abc transporter atp-binding protein
IPZ55_RS08590	COG4106	trans-aconitate 2-methyltransferase activity
IPZ55_RS08640	COG0142	geranyltranstransferase activity
IPZ55_RS08650	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IPZ55_RS08655	COG1959	2 iron, 2 sulfur cluster binding
IPZ55_RS08675	COG2515	1-aminocyclopropane-1-carboxylate deaminase
IPZ55_RS08690	COG2172	sigma factor antagonist activity
IPZ55_RS08705	COG1597	lipid kinase activity
IPZ55_RS08720	COG0363	glucosamine-6-phosphate deaminase activity
IPZ55_RS08725	COG1472	Belongs to the glycosyl hydrolase 3 family
IPZ55_RS08730	COG0395	ABC-type sugar transport system, permease component
IPZ55_RS08735	COG1175	transmembrane transport
IPZ55_RS08740	COG2182	Extracellular solute-binding protein
IPZ55_RS08745	COG2188	Transcriptional regulator
IPZ55_RS08750	COG1966	Carbon starvation protein
IPZ55_RS08770	COG2124	cytochrome p450
IPZ55_RS08780	COG0242	peptide deformylase activity
IPZ55_RS08790	COG5662	AntiSigma factor
IPZ55_RS08795	COG1595	DNA-templated transcription, initiation
IPZ55_RS08805	COG2135	peptidase activity
IPZ55_RS08815	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IPZ55_RS08825	COG2076	Multidrug Resistance protein
IPZ55_RS08835	COG0483	inositol monophosphate 1-phosphatase activity
IPZ55_RS08840	COG0753	catalase activity
IPZ55_RS08865	COG1615	UPF0182 protein
IPZ55_RS08875	COG3480	Lon protease (S16) C-terminal proteolytic domain
IPZ55_RS08970	COG0210	DNA helicase
IPZ55_RS09070	COG1432	Conserved Protein
IPZ55_RS09080	COG2095	MarC family integral membrane protein
IPZ55_RS09085	COG0613	PHP domain protein
IPZ55_RS09090	COG2814	Major facilitator Superfamily
IPZ55_RS09100	COG0598	Magnesium transport protein CorA
IPZ55_RS09140	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IPZ55_RS09145	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IPZ55_RS09155	COG1595	DNA-templated transcription, initiation
IPZ55_RS09170	COG1024	Enoyl-CoA hydratase
IPZ55_RS09180	COG0519	Catalyzes the synthesis of GMP from XMP
IPZ55_RS09215	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IPZ55_RS09245	COG0456	acetyltransferase
IPZ55_RS09250	COG2912	Transglutaminase-like superfamily
IPZ55_RS09260	COG1609	Transcriptional regulator
IPZ55_RS09265	COG1172	Belongs to the binding-protein-dependent transport system permease family
IPZ55_RS09275	COG1129	ABC transporter
IPZ55_RS09280	COG1879	ABC-type sugar transport system periplasmic component
IPZ55_RS09285	COG3250	beta-galactosidase activity
IPZ55_RS09305	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IPZ55_RS09340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IPZ55_RS09345	COG0601	transmembrane transport
IPZ55_RS09355	COG4608	Belongs to the ABC transporter superfamily
IPZ55_RS09360	COG0444	Belongs to the ABC transporter superfamily
IPZ55_RS09365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IPZ55_RS09370	COG0601	transmembrane transport
IPZ55_RS09380	COG1217	gtp-binding protein TYPA
IPZ55_RS09495	COG1028	Short-chain dehydrogenase reductase Sdr
IPZ55_RS09500	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IPZ55_RS09510	COG3473	Maleate cis-trans isomerase
IPZ55_RS09530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IPZ55_RS09535	COG0765	amino acid transport
IPZ55_RS09540	COG0765	amino acid transport
IPZ55_RS09545	COG1126	abc transporter atp-binding protein
IPZ55_RS09575	COG3397	chitin binding
IPZ55_RS09630	COG0673	inositol 2-dehydrogenase activity
IPZ55_RS09635	COG0179	Fumarylacetoacetate (FAA) hydrolase
IPZ55_RS09640	COG0706	membrane insertase activity
IPZ55_RS09665	COG2271	Major facilitator Superfamily
IPZ55_RS09670	COG2733	membrane
IPZ55_RS09700	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IPZ55_RS09710	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IPZ55_RS09735	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IPZ55_RS09745	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IPZ55_RS09750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IPZ55_RS09755	COG1263	PTS System
IPZ55_RS09765	COG1234	tRNA 3'-trailer cleavage
IPZ55_RS09790	COG1113	amino acid transport
IPZ55_RS09805	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IPZ55_RS09815	COG1335	isochorismatase
IPZ55_RS09850	COG0277	FAD linked oxidase domain protein
IPZ55_RS09860	COG3185	4-Hydroxyphenylpyruvate dioxygenase
IPZ55_RS09870	COG1174	glycine betaine transport
IPZ55_RS09875	COG0517	IMP dehydrogenase activity
IPZ55_RS09875	COG1125	glycine betaine transport
IPZ55_RS09880	COG1174	glycine betaine transport
IPZ55_RS09925	COG1116	anion transmembrane transporter activity
IPZ55_RS09945	COG2318	DinB family
IPZ55_RS09970	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IPZ55_RS09995	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IPZ55_RS10010	COG3525	Glycosyl hydrolase, family 20, catalytic domain
IPZ55_RS10015	COG0395	ABC-type sugar transport system, permease component
IPZ55_RS10020	COG1175	transmembrane transport
IPZ55_RS10035	COG1678	Uncharacterized ACR, COG1678
IPZ55_RS10040	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IPZ55_RS10045	COG0776	regulation of translation
IPZ55_RS10055	COG3973	AAA domain
IPZ55_RS10055	COG3973	AAA domain
IPZ55_RS10110	COG0583	DNA-binding transcription factor activity
IPZ55_RS10125	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IPZ55_RS10130	COG0793	Belongs to the peptidase S41A family
IPZ55_RS10140	COG2884	Cell division ATP-binding protein ftsE
IPZ55_RS10155	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IPZ55_RS10160	COG0515	serine threonine protein kinase
IPZ55_RS10165	COG0515	serine threonine protein kinase
IPZ55_RS10170	COG1716	ATPase activity
IPZ55_RS10175	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IPZ55_RS10180	COG1653	transport
IPZ55_RS10185	COG1175	transmembrane transport
IPZ55_RS10190	COG0395	ABC-type sugar transport system, permease component
IPZ55_RS10195	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IPZ55_RS10200	COG0438	transferase activity, transferring glycosyl groups
IPZ55_RS10205	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IPZ55_RS10215	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IPZ55_RS10225	COG2226	methyltransferase
IPZ55_RS10240	COG2902	Dehydrogenase
IPZ55_RS10260	COG0583	DNA-binding transcription factor activity
IPZ55_RS10265	COG5006	permease, DMT superfamily
IPZ55_RS10275	COG0653	protein targeting
IPZ55_RS10280	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IPZ55_RS10285	COG3214	Protein conserved in bacteria
IPZ55_RS10290	COG2197	response regulator
IPZ55_RS10295	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IPZ55_RS10305	COG0823	Involved in the tonB-independent uptake of proteins
IPZ55_RS10310	COG5002	protein histidine kinase activity
IPZ55_RS10315	COG0745	RESPONSE REGULATOR receiver
IPZ55_RS10320	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
IPZ55_RS10340	COG0714	Associated with various cellular activities
IPZ55_RS10345	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
IPZ55_RS10380	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IPZ55_RS10390	COG1482	cell wall glycoprotein biosynthetic process
IPZ55_RS10400	COG2835	tetraacyldisaccharide 4'-kinase activity
IPZ55_RS10420	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IPZ55_RS10430	COG1620	l-lactate permease
IPZ55_RS10470	COG0391	Required for morphogenesis under gluconeogenic growth conditions
IPZ55_RS10475	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
IPZ55_RS10475	COG0778	Nitroreductase
IPZ55_RS10510	COG1316	TRANSCRIPTIONal
IPZ55_RS10530	COG1316	TRANSCRIPTIONal
IPZ55_RS10535	COG3046	protein related to deoxyribodipyrimidine photolyase
IPZ55_RS10590	COG0753	catalase activity
IPZ55_RS10625	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IPZ55_RS10635	COG2072	flavoprotein involved in K transport
IPZ55_RS10660	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IPZ55_RS10675	COG2205	protein histidine kinase activity
IPZ55_RS10680	COG0745	RESPONSE REGULATOR receiver
IPZ55_RS10685	COG3104	oligopeptide transport
IPZ55_RS10695	COG1366	Belongs to the anti-sigma-factor antagonist family
IPZ55_RS10700	COG1191	sigma factor activity
IPZ55_RS10705	COG1228	amidohydrolase
IPZ55_RS10715	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IPZ55_RS10735	COG0395	ABC-type sugar transport system, permease component
IPZ55_RS10795	COG2755	lipolytic protein G-D-S-L family
IPZ55_RS10800	COG0183	Belongs to the thiolase family
IPZ55_RS10820	COG1476	TRANSCRIPTIONal
IPZ55_RS10835	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IPZ55_RS10845	COG1136	(ABC) transporter
IPZ55_RS10850	COG0577	efflux transmembrane transporter activity
IPZ55_RS10850	COG1136	(ABC) transporter
IPZ55_RS10855	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IPZ55_RS10860	COG1252	NADH dehydrogenase
IPZ55_RS10890	COG0148	phosphopyruvate hydratase activity
IPZ55_RS10905	COG2124	cytochrome p450
IPZ55_RS10940	COG1733	regulation of RNA biosynthetic process
IPZ55_RS10960	COG0667	Aldo Keto reductase
IPZ55_RS10995	COG0154	amidase activity
IPZ55_RS11000	COG3226	Transcriptional regulator
IPZ55_RS11010	COG1473	amidohydrolase
IPZ55_RS11065	COG3903	Transcriptional regulator
IPZ55_RS11065	COG3629	intracellular signal transduction
IPZ55_RS11075	COG0477	Major facilitator Superfamily
IPZ55_RS11105	COG0596	Alpha beta hydrolase
IPZ55_RS11115	COG1316	TRANSCRIPTIONal
IPZ55_RS11135	COG0789	Transcriptional regulator
IPZ55_RS11160	COG4585	Histidine kinase
IPZ55_RS11170	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IPZ55_RS11175	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IPZ55_RS11200	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IPZ55_RS11205	COG0193	aminoacyl-tRNA hydrolase activity
IPZ55_RS11215	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IPZ55_RS11235	COG4106	trans-aconitate 2-methyltransferase activity
IPZ55_RS11245	COG2197	response regulator
IPZ55_RS11250	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IPZ55_RS11295	COG0488	(ABC) transporter
IPZ55_RS11300	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IPZ55_RS11305	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IPZ55_RS11310	COG0084	hydrolase, TatD family'
IPZ55_RS11395	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IPZ55_RS11405	COG2409	Drug exporters of the RND superfamily
IPZ55_RS11415	COG0793	Belongs to the peptidase S41A family
IPZ55_RS11415	COG4946	Tricorn protease homolog
IPZ55_RS11425	COG4221	oxidoreductase activity
IPZ55_RS11435	COG2072	flavoprotein involved in K transport
IPZ55_RS11445	COG0708	Exodeoxyribonuclease III
IPZ55_RS11455	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IPZ55_RS11475	COG2197	response regulator
IPZ55_RS11515	COG0521	Mo-molybdopterin cofactor biosynthetic process
IPZ55_RS11515	COG0315	cyclic pyranopterin monophosphate synthase activity
IPZ55_RS11520	COG0315	cyclic pyranopterin monophosphate synthase activity
IPZ55_RS11530	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IPZ55_RS11535	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IPZ55_RS11545	COG3263	regulation of cellular component size
IPZ55_RS11560	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IPZ55_RS11575	COG1970	mechanosensitive ion channel activity
IPZ55_RS11590	COG3191	aminopeptidase activity
IPZ55_RS11610	COG3384	dioxygenase
IPZ55_RS11615	COG1846	Transcriptional regulator
IPZ55_RS11670	COG2050	protein possibly involved in aromatic compounds catabolism
IPZ55_RS11680	COG0183	Belongs to the thiolase family
IPZ55_RS11685	COG1024	Enoyl-CoA hydratase
IPZ55_RS11690	COG1250	3-hydroxyacyl-CoA dehydrogenase
IPZ55_RS11695	COG3396	Phenylacetate-CoA oxygenase
IPZ55_RS11700	COG3460	Phenylacetate-CoA oxygenase
IPZ55_RS11705	COG3396	Phenylacetate-CoA oxygenase
IPZ55_RS11710	COG2151	metal-sulfur cluster biosynthetic enzyme
IPZ55_RS11715	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IPZ55_RS11770	COG1278	Cold shock
IPZ55_RS11835	COG3547	Transposase (IS116 IS110 IS902 family)
IPZ55_RS11855	COG5297	Belongs to the glycosyl hydrolase family 6
IPZ55_RS11875	COG0148	phosphopyruvate hydratase activity
IPZ55_RS11890	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
IPZ55_RS11920	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IPZ55_RS11960	COG0515	serine threonine protein kinase
IPZ55_RS11960	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IPZ55_RS11965	COG1309	transcriptional regulator
IPZ55_RS11985	COG2072	flavoprotein involved in K transport
IPZ55_RS11990	COG2271	Major facilitator Superfamily
IPZ55_RS12010	COG1366	Belongs to the anti-sigma-factor antagonist family
IPZ55_RS12090	COG4821	SIS domain
IPZ55_RS12100	COG0259	pyridoxamine-phosphate oxidase activity
IPZ55_RS12120	COG1024	Enoyl-CoA hydratase
IPZ55_RS12135	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IPZ55_RS12165	COG0583	DNA-binding transcription factor activity
IPZ55_RS12175	COG0247	lactate metabolic process
IPZ55_RS12175	COG0277	FAD linked oxidase domain protein
IPZ55_RS12180	COG2205	protein histidine kinase activity
IPZ55_RS12200	COG2124	cytochrome p450
IPZ55_RS12210	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IPZ55_RS12305	COG0667	Aldo Keto reductase
IPZ55_RS12330	COG2252	PERMEase
IPZ55_RS12340	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IPZ55_RS12365	COG2814	Major facilitator Superfamily
IPZ55_RS12375	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IPZ55_RS12380	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
IPZ55_RS12395	COG2197	response regulator
IPZ55_RS12400	COG1132	(ABC) transporter
IPZ55_RS12405	COG1132	(ABC) transporter
IPZ55_RS12415	COG0515	serine threonine protein kinase
IPZ55_RS12420	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IPZ55_RS12425	COG1120	ATPase activity
IPZ55_RS12430	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPZ55_RS12435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPZ55_RS12445	COG1295	ribonuclease BN
IPZ55_RS12455	COG2124	cytochrome p450
IPZ55_RS12510	COG1061	Type III restriction enzyme res subunit
IPZ55_RS12545	COG0667	Aldo Keto reductase
IPZ55_RS12550	COG0789	Transcriptional regulator
IPZ55_RS12575	COG3973	AAA domain
IPZ55_RS12625	COG4585	Histidine kinase
IPZ55_RS12630	COG2197	response regulator
IPZ55_RS12650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IPZ55_RS12685	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IPZ55_RS12720	COG0406	alpha-ribazole phosphatase activity
IPZ55_RS12730	COG1737	Transcriptional regulator
IPZ55_RS12735	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IPZ55_RS12740	COG1263	PTS System
IPZ55_RS12740	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IPZ55_RS12745	COG0667	Aldo Keto reductase
IPZ55_RS12785	COG1278	Cold shock
IPZ55_RS12800	COG0463	Glycosyl transferase, family 2
IPZ55_RS12825	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IPZ55_RS12865	COG1105	Belongs to the carbohydrate kinase PfkB family
IPZ55_RS12890	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IPZ55_RS12920	COG1309	transcriptional regulator
IPZ55_RS12935	COG0577	efflux transmembrane transporter activity
IPZ55_RS12935	COG1136	(ABC) transporter
IPZ55_RS12970	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IPZ55_RS13040	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IPZ55_RS13110	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
IPZ55_RS13130	COG1366	Belongs to the anti-sigma-factor antagonist family
IPZ55_RS13135	COG1366	Belongs to the anti-sigma-factor antagonist family
IPZ55_RS13140	COG2172	sigma factor antagonist activity
IPZ55_RS13165	COG0577	efflux transmembrane transporter activity
IPZ55_RS13165	COG1136	(ABC) transporter
IPZ55_RS13220	COG2409	Drug exporters of the RND superfamily
IPZ55_RS13230	COG4585	Histidine kinase
IPZ55_RS13235	COG2197	response regulator
IPZ55_RS13240	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IPZ55_RS13245	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IPZ55_RS13265	COG0301	tRNA thio-modification
IPZ55_RS13285	COG0513	Belongs to the DEAD box helicase family
IPZ55_RS13290	COG1278	Cold shock
IPZ55_RS13320	COG2208	phosphoserine phosphatase activity
IPZ55_RS13320	COG2770	Histidine kinase
IPZ55_RS13355	COG0456	acetyltransferase
IPZ55_RS13365	COG0436	Aminotransferase
IPZ55_RS13375	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IPZ55_RS13385	COG3486	L-lysine 6-monooxygenase (NADPH) activity
IPZ55_RS13395	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IPZ55_RS13395	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IPZ55_RS13440	COG2814	Major facilitator Superfamily
IPZ55_RS13450	COG3842	ATPase activity
IPZ55_RS13460	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IPZ55_RS13470	COG1253	flavin adenine dinucleotide binding
IPZ55_RS13485	COG0215	cysteine-tRNA ligase activity
IPZ55_RS13500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IPZ55_RS13520	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
IPZ55_RS13525	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
IPZ55_RS13530	COG1329	Transcriptional regulator
IPZ55_RS13540	COG0745	RESPONSE REGULATOR receiver
IPZ55_RS13545	COG5002	protein histidine kinase activity
IPZ55_RS13560	COG2076	Multidrug Resistance protein
IPZ55_RS13585	COG3311	Transcriptional regulator
IPZ55_RS13650	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IPZ55_RS13685	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
IPZ55_RS13705	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IPZ55_RS13710	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IPZ55_RS13740	COG4942	peptidase
IPZ55_RS13745	COG0783	Belongs to the Dps family
IPZ55_RS13750	COG1120	ATPase activity
IPZ55_RS13755	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPZ55_RS13775	COG5001	Diguanylate cyclase
IPZ55_RS13790	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IPZ55_RS13810	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IPZ55_RS13815	COG1316	TRANSCRIPTIONal
IPZ55_RS13825	COG0640	Transcriptional regulator
IPZ55_RS13835	COG1252	NADH dehydrogenase
IPZ55_RS13865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IPZ55_RS13875	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IPZ55_RS13885	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IPZ55_RS13915	COG2186	Transcriptional regulator
IPZ55_RS13925	COG0318	PFAM AMP-dependent synthetase and ligase
IPZ55_RS13930	COG0825	malonyl-CoA metabolic process
IPZ55_RS13930	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IPZ55_RS13940	COG0789	Transcriptional regulator
IPZ55_RS13955	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IPZ55_RS13960	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IPZ55_RS13975	COG0789	Transcriptional regulator
IPZ55_RS13995	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IPZ55_RS14010	COG2197	response regulator
IPZ55_RS14025	COG1028	Short-chain dehydrogenase reductase Sdr
IPZ55_RS14040	COG2249	NAD(P)H dehydrogenase (quinone) activity
IPZ55_RS14055	COG0537	adenosine 5'-monophosphoramidase activity
IPZ55_RS14095	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IPZ55_RS14100	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IPZ55_RS14100	COG1754	DNA topoisomerase type I activity
IPZ55_RS14110	COG2890	protein-(glutamine-N5) methyltransferase activity
IPZ55_RS14125	COG1366	Belongs to the anti-sigma-factor antagonist family
IPZ55_RS14130	COG1205	dead DEAH box helicase
IPZ55_RS14130	COG1111	helicase
IPZ55_RS14195	COG0515	serine threonine protein kinase
IPZ55_RS14195	COG2815	serine threonine protein kinase
IPZ55_RS14265	COG0659	secondary active sulfate transmembrane transporter activity
IPZ55_RS14270	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IPZ55_RS14275	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IPZ55_RS14285	COG2267	carboxylic ester hydrolase activity
IPZ55_RS14315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IPZ55_RS14325	COG0251	oxidation-reduction process
IPZ55_RS14340	COG0003	Pfam Anion-transporting ATPase
IPZ55_RS14360	COG1408	metallophosphoesterase
IPZ55_RS14370	COG0270	DNA (cytosine-5-)-methyltransferase activity
IPZ55_RS14425	COG2318	DinB family
IPZ55_RS14450	COG0596	Alpha beta hydrolase
IPZ55_RS14470	COG2130	NADP-dependent
IPZ55_RS14510	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IPZ55_RS14520	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IPZ55_RS14525	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IPZ55_RS14600	COG0666	response to abiotic stimulus
IPZ55_RS14615	COG2197	response regulator
IPZ55_RS14665	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IPZ55_RS14760	COG1470	cell adhesion involved in biofilm formation
IPZ55_RS14760	COG0366	Alpha amylase catalytic
IPZ55_RS14775	COG0579	oxidoreductase
IPZ55_RS14780	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IPZ55_RS14790	COG0667	Aldo Keto reductase
IPZ55_RS14820	COG0542	response to heat
IPZ55_RS14850	COG0513	Belongs to the DEAD box helicase family
IPZ55_RS14885	COG1643	Atp-dependent helicase
IPZ55_RS14920	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IPZ55_RS14935	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IPZ55_RS14940	COG0047	phosphoribosylformylglycinamidine synthase activity
IPZ55_RS14945	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IPZ55_RS14980	COG2197	response regulator
IPZ55_RS14990	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
IPZ55_RS15005	COG0151	Belongs to the GarS family
IPZ55_RS15030	COG0659	secondary active sulfate transmembrane transporter activity
IPZ55_RS15040	COG2837	iron assimilation
IPZ55_RS15055	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IPZ55_RS15120	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IPZ55_RS15155	COG1191	sigma factor activity
IPZ55_RS15160	COG1191	sigma factor activity
IPZ55_RS15175	COG0477	Major facilitator Superfamily
IPZ55_RS15195	COG0477	Major facilitator Superfamily
IPZ55_RS15205	COG0745	RESPONSE REGULATOR receiver
IPZ55_RS15240	COG0318	PFAM AMP-dependent synthetase and ligase
IPZ55_RS15245	COG1595	DNA-templated transcription, initiation
IPZ55_RS15265	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IPZ55_RS15280	COG0653	protein targeting
IPZ55_RS15295	COG0006	proline dipeptidase activity
IPZ55_RS15315	COG1999	signal sequence binding
IPZ55_RS15330	COG2837	iron assimilation
IPZ55_RS15335	COG0077	Prephenate dehydratase
IPZ55_RS15340	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IPZ55_RS15345	COG0561	phosphatase activity
IPZ55_RS15365	COG1131	(ABC) transporter
IPZ55_RS15385	COG0561	phosphatase activity
IPZ55_RS15390	COG0739	heme binding
IPZ55_RS15390	COG0741	lytic transglycosylase activity
IPZ55_RS15390	COG1196	nuclear chromosome segregation
IPZ55_RS15400	COG4988	ABC transporter
IPZ55_RS15405	COG1294	oxidase, subunit
IPZ55_RS15410	COG1271	oxidase subunit
IPZ55_RS15415	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IPZ55_RS15420	COG1609	Transcriptional regulator
IPZ55_RS15435	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IPZ55_RS15460	COG0662	Cupin 2, conserved barrel domain protein
IPZ55_RS15465	COG1950	PFAM Membrane protein of
IPZ55_RS15470	COG0626	cystathionine gamma-synthase activity
IPZ55_RS15515	COG0110	maltose O-acetyltransferase activity
IPZ55_RS15520	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IPZ55_RS15525	COG0305	Participates in initiation and elongation during chromosome replication
IPZ55_RS15535	COG0359	binds to the 23S rRNA
IPZ55_RS15540	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IPZ55_RS15545	COG0629	single-stranded DNA binding
IPZ55_RS15550	COG0360	Binds together with S18 to 16S ribosomal RNA
IPZ55_RS15575	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IPZ55_RS15600	COG0617	tRNA 3'-terminal CCA addition
IPZ55_RS15615	COG2815	serine threonine protein kinase
IPZ55_RS15615	COG0515	serine threonine protein kinase
IPZ55_RS15620	COG1595	DNA-templated transcription, initiation
IPZ55_RS15630	COG0492	ferredoxin-NADP+ reductase activity
IPZ55_RS15635	COG3118	belongs to the thioredoxin family
IPZ55_RS15650	COG1192	Involved in chromosome partitioning
IPZ55_RS15655	COG0357	Ribosomal RNA small subunit methyltransferase G
IPZ55_RS15665	COG0706	membrane insertase activity
IPZ55_RS15670	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
IPZ55_RS15675	COG0594	ribonuclease P activity
IPZ55_RS15680	COG0230	Belongs to the bacterial ribosomal protein bL34 family
IPZ55_RS15685	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IPZ55_RS15690	COG0592	DNA-directed DNA polymerase activity
IPZ55_RS15695	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
IPZ55_RS15700	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IPZ55_RS15705	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
IPZ55_RS15710	COG0187	DNA topoisomerase II activity
IPZ55_RS15715	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IPZ55_RS15755	COG0515	serine threonine protein kinase
IPZ55_RS15785	COG1278	Cold shock
IPZ55_RS15790	COG1309	transcriptional regulator
IPZ55_RS15810	COG0705	Rhomboid family
IPZ55_RS15830	COG3764	Sortase (surface protein transpeptidase)
IPZ55_RS15835	COG3764	Sortase (surface protein transpeptidase)
IPZ55_RS15840	COG0515	serine threonine protein kinase
IPZ55_RS15860	COG1716	ATPase activity
IPZ55_RS15865	COG1716	ATPase activity
IPZ55_RS15875	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IPZ55_RS15880	COG1733	regulation of RNA biosynthetic process
IPZ55_RS15920	COG1522	sequence-specific DNA binding
IPZ55_RS15945	COG0303	'Molybdopterin
IPZ55_RS15950	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IPZ55_RS15955	COG0604	alcohol dehydrogenase
IPZ55_RS15975	COG0515	serine threonine protein kinase
IPZ55_RS15980	COG0515	serine threonine protein kinase
IPZ55_RS15995	COG0022	dehydrogenase e1 component
IPZ55_RS16000	COG0508	dehydrogenase complex catalyzes the overall conversion of
IPZ55_RS16060	COG1362	aminopeptidase activity
IPZ55_RS16080	COG1960	acyl-CoA dehydrogenase activity
IPZ55_RS16090	COG1741	Belongs to the pirin family
IPZ55_RS16095	COG0628	permease
IPZ55_RS16105	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IPZ55_RS16115	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IPZ55_RS16160	COG1316	TRANSCRIPTIONal
IPZ55_RS16175	COG2268	Band 7 protein
IPZ55_RS16180	COG1937	Protein conserved in bacteria
IPZ55_RS16185	COG1064	alcohol dehydrogenase
IPZ55_RS16190	COG2770	Histidine kinase
IPZ55_RS16190	COG2208	phosphoserine phosphatase activity
IPZ55_RS16220	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IPZ55_RS16240	COG0477	Major facilitator Superfamily
IPZ55_RS16265	COG0657	acetylesterase activity
IPZ55_RS16270	COG0247	lactate metabolic process
IPZ55_RS16270	COG2181	nitrate reductase activity
IPZ55_RS16300	COG0717	Belongs to the dCTP deaminase family
IPZ55_RS16325	COG2814	Major facilitator Superfamily
IPZ55_RS16335	COG1695	Transcriptional regulator
IPZ55_RS16365	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IPZ55_RS16365	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IPZ55_RS16405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPZ55_RS16410	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPZ55_RS16415	COG1120	ATPase activity
IPZ55_RS16470	COG2188	Transcriptional regulator
IPZ55_RS16495	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
IPZ55_RS16515	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IPZ55_RS16525	COG1131	(ABC) transporter
IPZ55_RS16530	COG1725	Transcriptional regulator
IPZ55_RS16565	COG0443	Heat shock 70 kDa protein
IPZ55_RS16570	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IPZ55_RS16575	COG0484	heat shock protein binding
IPZ55_RS16580	COG0789	Transcriptional regulator
IPZ55_RS16605	COG0477	Major facilitator Superfamily
IPZ55_RS16620	COG2378	regulation of single-species biofilm formation
IPZ55_RS16660	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IPZ55_RS16675	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IPZ55_RS16680	COG0191	fructose-bisphosphate aldolase activity
IPZ55_RS16685	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
IPZ55_RS16690	COG0477	Major facilitator Superfamily
IPZ55_RS16710	COG3844	kynureninase activity
IPZ55_RS16720	COG0702	epimerase
IPZ55_RS16725	COG4585	Histidine kinase
IPZ55_RS16730	COG2197	response regulator
IPZ55_RS16740	COG1335	isochorismatase
IPZ55_RS16755	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IPZ55_RS16770	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IPZ55_RS16775	COG0798	PFAM Bile acid sodium symporter
IPZ55_RS16790	COG2267	carboxylic ester hydrolase activity
IPZ55_RS16795	COG2124	cytochrome p450
IPZ55_RS16800	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IPZ55_RS16805	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IPZ55_RS16810	COG0477	Major facilitator Superfamily
IPZ55_RS16865	COG0509	glycine decarboxylation via glycine cleavage system
IPZ55_RS16875	COG2318	DinB family
IPZ55_RS16895	COG1196	nuclear chromosome segregation
IPZ55_RS16895	COG0741	lytic transglycosylase activity
IPZ55_RS16895	COG0739	heme binding
IPZ55_RS16900	COG0671	phosphoesterase, PA-phosphatase related
IPZ55_RS16915	COG1028	Short-chain dehydrogenase reductase Sdr
IPZ55_RS16925	COG1937	Protein conserved in bacteria
IPZ55_RS16935	COG0306	phosphate transporter
IPZ55_RS16940	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IPZ55_RS16960	COG0406	alpha-ribazole phosphatase activity
IPZ55_RS16960	COG0494	nUDIX hydrolase
IPZ55_RS16995	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IPZ55_RS17000	COG2318	DinB family
IPZ55_RS17050	COG2770	Histidine kinase
IPZ55_RS17050	COG2208	phosphoserine phosphatase activity
IPZ55_RS17065	COG3629	intracellular signal transduction
IPZ55_RS17065	COG3903	Transcriptional regulator
IPZ55_RS17105	COG1595	DNA-templated transcription, initiation
IPZ55_RS17155	COG2267	carboxylic ester hydrolase activity
IPZ55_RS17180	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IPZ55_RS17215	COG1476	TRANSCRIPTIONal
IPZ55_RS17240	COG0789	Transcriptional regulator
IPZ55_RS17255	COG1490	D-aminoacyl-tRNA deacylase activity
IPZ55_RS17260	COG0404	The glycine cleavage system catalyzes the degradation of glycine
IPZ55_RS17265	COG0735	belongs to the Fur family
IPZ55_RS17270	COG3485	protocatechuate 3,4-dioxygenase
IPZ55_RS17305	COG2897	thiosulfate sulfurtransferase activity
IPZ55_RS17330	COG0745	RESPONSE REGULATOR receiver
IPZ55_RS17335	COG1609	Transcriptional regulator
IPZ55_RS17340	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IPZ55_RS17345	COG0745	RESPONSE REGULATOR receiver
IPZ55_RS17360	COG4214	carbohydrate transport
IPZ55_RS17365	COG1129	ABC transporter
IPZ55_RS17375	COG1609	Transcriptional regulator
IPZ55_RS17385	COG2160	L-arabinose isomerase activity
IPZ55_RS17390	COG0235	Class ii aldolase
IPZ55_RS17395	COG0737	Belongs to the 5'-nucleotidase family
IPZ55_RS17400	COG0456	acetyltransferase
IPZ55_RS17450	COG4941	Belongs to the sigma-70 factor family
IPZ55_RS17455	COG1725	Transcriptional regulator
IPZ55_RS17465	COG1131	(ABC) transporter
IPZ55_RS17495	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IPZ55_RS17505	COG2226	methyltransferase
IPZ55_RS17550	COG3103	Sh3 type 3 domain protein
IPZ55_RS17550	COG1388	LysM domain
IPZ55_RS17550	COG0791	NLP P60 protein
IPZ55_RS17560	COG0438	transferase activity, transferring glycosyl groups
IPZ55_RS17585	COG0588	phosphoglycerate mutase activity
IPZ55_RS17615	COG0739	heme binding
IPZ55_RS17630	COG2814	Major facilitator Superfamily
IPZ55_RS17630	COG0477	Major facilitator Superfamily
IPZ55_RS17645	COG2159	amidohydrolase
IPZ55_RS17650	COG2828	Protein conserved in bacteria
IPZ55_RS17655	COG2186	Transcriptional regulator
IPZ55_RS17685	COG0501	Belongs to the peptidase M48B family
IPZ55_RS17705	COG3547	Transposase (IS116 IS110 IS902 family)
IPZ55_RS17735	COG1289	transmembrane transporter activity
IPZ55_RS17760	COG1012	belongs to the aldehyde dehydrogenase family
IPZ55_RS17765	COG2318	DinB family
IPZ55_RS17775	COG0655	NAD(P)H dehydrogenase (quinone) activity
IPZ55_RS17780	COG0789	Transcriptional regulator
IPZ55_RS17785	COG0586	Pfam SNARE associated Golgi protein
IPZ55_RS17795	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IPZ55_RS17800	COG2027	D-alanyl-D-alanine carboxypeptidase
IPZ55_RS17810	COG0037	tRNA processing
IPZ55_RS17825	COG0302	gtp cyclohydrolase
IPZ55_RS17835	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IPZ55_RS17840	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IPZ55_RS17855	COG0517	IMP dehydrogenase activity
IPZ55_RS17855	COG1125	glycine betaine transport
IPZ55_RS17860	COG1174	glycine betaine transport
IPZ55_RS17865	COG1174	glycine betaine transport
IPZ55_RS17870	COG1732	Glycine betaine
IPZ55_RS17880	COG0477	Major facilitator Superfamily
IPZ55_RS17885	COG0477	Major facilitator Superfamily
IPZ55_RS17890	COG0477	Major facilitator Superfamily
IPZ55_RS17965	COG1012	belongs to the aldehyde dehydrogenase family
IPZ55_RS17985	COG4585	Histidine kinase
IPZ55_RS17990	COG2197	response regulator
IPZ55_RS18010	COG0649	NAD binding
IPZ55_RS18025	COG2197	response regulator
IPZ55_RS18040	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IPZ55_RS18045	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
IPZ55_RS18055	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IPZ55_RS18075	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IPZ55_RS18105	COG0739	heme binding
IPZ55_RS18110	COG2205	protein histidine kinase activity
IPZ55_RS18115	COG0745	RESPONSE REGULATOR receiver
IPZ55_RS18125	COG1595	DNA-templated transcription, initiation
IPZ55_RS18135	COG0671	phosphoesterase, PA-phosphatase related
IPZ55_RS18145	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
IPZ55_RS18180	COG0248	Ppx GppA phosphatase
IPZ55_RS18190	COG1082	Xylose isomerase domain protein TIM barrel
IPZ55_RS18200	COG0129	dihydroxy-acid dehydratase activity
IPZ55_RS18210	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IPZ55_RS18230	COG0842	Transport permease protein
IPZ55_RS18230	COG1129	ABC transporter
IPZ55_RS18240	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IPZ55_RS18245	COG0180	Tryptophanyl-tRNA synthetase
IPZ55_RS18275	COG0123	including yeast histone deacetylase and acetoin utilization protein
IPZ55_RS18305	COG4552	Acetyltransferase involved in intracellular survival and related
IPZ55_RS18335	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IPZ55_RS18340	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IPZ55_RS18345	COG0181	hydroxymethylbilane synthase activity
IPZ55_RS18350	COG1648	precorrin-2 dehydrogenase activity
IPZ55_RS18350	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IPZ55_RS18355	COG0113	porphobilinogen synthase activity
IPZ55_RS18375	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IPZ55_RS18380	COG0018	arginyl-trna synthetase
IPZ55_RS18385	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
IPZ55_RS18410	COG1690	Belongs to the RtcB family
IPZ55_RS18415	COG0659	secondary active sulfate transmembrane transporter activity
IPZ55_RS18465	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IPZ55_RS18470	COG0406	alpha-ribazole phosphatase activity
IPZ55_RS18480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IPZ55_RS18485	COG0785	Cytochrome C biogenesis protein
IPZ55_RS18495	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IPZ55_RS18510	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
IPZ55_RS18515	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IPZ55_RS18520	COG0163	prenyltransferase activity
IPZ55_RS18535	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
IPZ55_RS18550	COG1301	dicarboxylic acid transport
IPZ55_RS18565	COG1131	(ABC) transporter
IPZ55_RS18570	COG3559	Exporter of polyketide antibiotics
IPZ55_RS18600	COG0183	Belongs to the thiolase family
IPZ55_RS18610	COG1278	Cold shock
IPZ55_RS18615	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
IPZ55_RS18740	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
IPZ55_RS18800	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
IPZ55_RS18810	COG2226	methyltransferase
IPZ55_RS18835	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IPZ55_RS18840	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IPZ55_RS18845	COG0649	NAD binding
IPZ55_RS18855	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IPZ55_RS18860	COG1034	ATP synthesis coupled electron transport
IPZ55_RS18865	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
IPZ55_RS18870	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IPZ55_RS18875	COG0839	Belongs to the complex I subunit 6 family
IPZ55_RS18880	COG0713	ATP synthesis coupled electron transport
IPZ55_RS18885	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IPZ55_RS18895	COG1007	ATP synthesis coupled electron transport
IPZ55_RS18900	COG0514	ATP-dependent DNA helicase (RecQ)
IPZ55_RS18920	COG0561	phosphatase activity
IPZ55_RS18930	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IPZ55_RS18950	COG3104	oligopeptide transport
IPZ55_RS18955	COG0142	geranyltranstransferase activity
IPZ55_RS18975	COG0488	(ABC) transporter
IPZ55_RS18985	COG0702	epimerase
IPZ55_RS18990	COG1733	regulation of RNA biosynthetic process
IPZ55_RS18995	COG1013	pyruvate-flavodoxin oxidoreductase activity
IPZ55_RS19000	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
IPZ55_RS19000	COG0674	pyruvate-flavodoxin oxidoreductase activity
IPZ55_RS19005	COG2197	response regulator
IPZ55_RS19010	COG4585	Histidine kinase
IPZ55_RS19020	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IPZ55_RS19025	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IPZ55_RS19030	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IPZ55_RS19035	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
IPZ55_RS19040	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IPZ55_RS19045	COG0839	Belongs to the complex I subunit 6 family
IPZ55_RS19050	COG0713	ATP synthesis coupled electron transport
IPZ55_RS19055	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IPZ55_RS19065	COG1007	ATP synthesis coupled electron transport
IPZ55_RS19070	COG0501	Belongs to the peptidase M48B family
IPZ55_RS19075	COG3304	Inner membrane component domain
IPZ55_RS19080	COG2261	transglycosylase associated protein
IPZ55_RS19085	COG1666	GTP binding
IPZ55_RS19100	COG0702	epimerase
IPZ55_RS19105	COG0402	S-adenosylhomocysteine deaminase activity
IPZ55_RS19120	COG0267	Belongs to the bacterial ribosomal protein bL33 family
IPZ55_RS19125	COG2030	dehydratase
IPZ55_RS19135	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IPZ55_RS19145	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IPZ55_RS19150	COG0436	Aminotransferase
IPZ55_RS19175	COG0081	regulation of translation
IPZ55_RS19185	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IPZ55_RS19190	COG0222	ribosome binding
IPZ55_RS19195	COG0085	RNA polymerase activity
IPZ55_RS19200	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IPZ55_RS19235	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IPZ55_RS19240	COG0049	tRNA binding
IPZ55_RS19245	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IPZ55_RS19265	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
IPZ55_RS19275	COG0051	transcription antitermination factor activity, RNA binding
IPZ55_RS19280	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IPZ55_RS19285	COG0088	Forms part of the polypeptide exit tunnel
IPZ55_RS19290	COG0089	rRNA binding
IPZ55_RS19295	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IPZ55_RS19300	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IPZ55_RS19305	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IPZ55_RS19310	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IPZ55_RS19315	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IPZ55_RS19320	COG0255	Belongs to the universal ribosomal protein uL29 family
IPZ55_RS19325	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IPZ55_RS19330	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IPZ55_RS19335	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IPZ55_RS19340	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IPZ55_RS19345	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IPZ55_RS19350	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IPZ55_RS19355	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IPZ55_RS19360	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IPZ55_RS19365	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IPZ55_RS19370	COG1841	ribosomal large subunit assembly
IPZ55_RS19375	COG0200	Binds to the 23S rRNA
IPZ55_RS19380	COG0201	protein transport
IPZ55_RS19385	COG0563	adenylate kinase activity
IPZ55_RS19395	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IPZ55_RS19400	COG0257	Belongs to the bacterial ribosomal protein bL36 family
IPZ55_RS19405	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IPZ55_RS19410	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IPZ55_RS19420	COG0203	ribosomal protein L17
IPZ55_RS19425	COG0101	tRNA pseudouridine synthase activity
IPZ55_RS19435	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IPZ55_RS19440	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IPZ55_RS19445	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IPZ55_RS19450	COG1072	(Pantothenic acid kinase))
IPZ55_RS19465	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IPZ55_RS19480	COG4977	sequence-specific DNA binding
IPZ55_RS19495	COG0736	holo-[acyl-carrier-protein] synthase activity
IPZ55_RS19560	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IPZ55_RS19570	COG0802	atpase or kinase
IPZ55_RS19595	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IPZ55_RS19630	COG0726	polysaccharide deacetylase
IPZ55_RS19645	COG4221	oxidoreductase activity
IPZ55_RS19650	COG0583	DNA-binding transcription factor activity
IPZ55_RS19660	COG2197	response regulator
IPZ55_RS19665	COG1595	DNA-templated transcription, initiation
IPZ55_RS19675	COG0516	GMP reductase activity
IPZ55_RS19685	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IPZ55_RS19720	COG1012	belongs to the aldehyde dehydrogenase family
IPZ55_RS19740	COG0519	Catalyzes the synthesis of GMP from XMP
IPZ55_RS19740	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IPZ55_RS19750	COG1028	Short-chain dehydrogenase reductase Sdr
IPZ55_RS19790	COG2197	response regulator
IPZ55_RS19795	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IPZ55_RS19840	COG0456	acetyltransferase
IPZ55_RS19840	COG1846	Transcriptional regulator
IPZ55_RS19850	COG1228	amidohydrolase
IPZ55_RS19875	COG0791	NLP P60 protein
IPZ55_RS19925	COG1196	nuclear chromosome segregation
IPZ55_RS19925	COG0741	lytic transglycosylase activity
IPZ55_RS19925	COG0739	heme binding
IPZ55_RS19930	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
IPZ55_RS19935	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IPZ55_RS19935	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IPZ55_RS19950	COG0714	Associated with various cellular activities
IPZ55_RS19955	COG2425	protein containing a von Willebrand factor type A (vWA) domain
IPZ55_RS19960	COG3552	Protein containing von Willebrand factor type A (VWA) domain
IPZ55_RS19965	COG0045	succinate-CoA ligase (ADP-forming) activity
IPZ55_RS19995	COG0138	bifunctional purine biosynthesis protein purh
IPZ55_RS20005	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IPZ55_RS20020	COG2197	response regulator
IPZ55_RS20040	COG0039	L-malate dehydrogenase activity
IPZ55_RS20060	COG1012	belongs to the aldehyde dehydrogenase family
IPZ55_RS20070	COG0517	IMP dehydrogenase activity
IPZ55_RS20070	COG4175	Glycine betaine
IPZ55_RS20100	COG0395	ABC-type sugar transport system, permease component
IPZ55_RS20105	COG1175	transmembrane transport
IPZ55_RS20125	COG2362	D-Aminopeptidase
IPZ55_RS20130	COG1609	Transcriptional regulator
IPZ55_RS20140	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IPZ55_RS20145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IPZ55_RS20155	COG0754	glutathionylspermidine amidase activity
IPZ55_RS20165	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IPZ55_RS20205	COG0180	Tryptophanyl-tRNA synthetase
IPZ55_RS20245	COG1295	ribonuclease BN
IPZ55_RS20260	COG1408	metallophosphoesterase
IPZ55_RS20280	COG1309	transcriptional regulator
IPZ55_RS20295	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IPZ55_RS20300	COG1053	succinate dehydrogenase
IPZ55_RS20310	COG2009	succinate dehydrogenase
IPZ55_RS20350	COG1215	transferase activity, transferring glycosyl groups
IPZ55_RS20355	COG1595	DNA-templated transcription, initiation
IPZ55_RS20425	COG1216	Glycosyl transferase, family 2
IPZ55_RS20435	COG1083	cytidylyl-transferase
IPZ55_RS20440	COG2089	acid synthase
IPZ55_RS20450	COG1473	amidohydrolase
IPZ55_RS20450	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
IPZ55_RS20460	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IPZ55_RS20490	COG1744	ABC transporter substrate-binding protein PnrA-like
IPZ55_RS20495	COG3845	ABC transporter
IPZ55_RS20500	COG4603	Belongs to the binding-protein-dependent transport system permease family
IPZ55_RS20505	COG1079	Belongs to the binding-protein-dependent transport system permease family
IPZ55_RS20545	COG2814	Major facilitator Superfamily
IPZ55_RS20550	COG0583	DNA-binding transcription factor activity
IPZ55_RS20575	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IPZ55_RS20600	COG2205	protein histidine kinase activity
IPZ55_RS20605	COG0745	RESPONSE REGULATOR receiver
IPZ55_RS20655	COG1012	belongs to the aldehyde dehydrogenase family
IPZ55_RS20675	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IPZ55_RS20715	COG4770	biotin carboxylase activity
IPZ55_RS20725	COG0424	maF-like protein
IPZ55_RS20740	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IPZ55_RS20750	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
IPZ55_RS20755	COG1024	Enoyl-CoA hydratase
IPZ55_RS20765	COG2986	histidine ammonia-lyase
IPZ55_RS20785	COG1136	(ABC) transporter
IPZ55_RS20790	COG1064	alcohol dehydrogenase
IPZ55_RS20795	COG2318	DinB family
IPZ55_RS20820	COG2255	four-way junction helicase activity
IPZ55_RS20825	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IPZ55_RS20840	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IPZ55_RS20850	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IPZ55_RS20885	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IPZ55_RS20910	COG1331	Highly conserved protein containing a thioredoxin domain
IPZ55_RS20930	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
IPZ55_RS20960	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
IPZ55_RS20975	COG1414	Transcriptional regulator
IPZ55_RS20980	COG0251	oxidation-reduction process
IPZ55_RS21060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IPZ55_RS21095	COG2894	cell division
IPZ55_RS21160	COG2814	Major facilitator Superfamily
IPZ55_RS21165	COG0656	L-ascorbic acid biosynthetic process
IPZ55_RS21180	COG3548	integral membrane protein
IPZ55_RS21195	COG0667	Aldo Keto reductase
IPZ55_RS21200	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IPZ55_RS21205	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
IPZ55_RS21225	COG0450	alkyl hydroperoxide reductase
IPZ55_RS21230	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IPZ55_RS21240	COG1136	(ABC) transporter
IPZ55_RS21260	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IPZ55_RS21275	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IPZ55_RS21285	COG0114	fumarate hydratase activity
IPZ55_RS21295	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IPZ55_RS21295	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IPZ55_RS21305	COG0515	serine threonine protein kinase
IPZ55_RS21330	COG0778	Nitroreductase
IPZ55_RS21335	COG1722	exodeoxyribonuclease VII activity
IPZ55_RS21340	COG1570	exodeoxyribonuclease VII activity
IPZ55_RS21345	COG0531	amino acid
IPZ55_RS21350	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IPZ55_RS21365	COG0012	GTP binding
IPZ55_RS21395	COG0709	Synthesizes selenophosphate from selenide and ATP
IPZ55_RS21430	COG0406	alpha-ribazole phosphatase activity
IPZ55_RS21455	COG0745	RESPONSE REGULATOR receiver
IPZ55_RS21470	COG2985	domain, Protein
IPZ55_RS21530	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IPZ55_RS21535	COG4977	sequence-specific DNA binding
IPZ55_RS21550	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IPZ55_RS21575	COG3486	L-lysine 6-monooxygenase (NADPH) activity
IPZ55_RS21605	COG1028	Short-chain dehydrogenase reductase Sdr
IPZ55_RS21615	COG3655	Transcriptional regulator
IPZ55_RS21670	COG1960	acyl-CoA dehydrogenase activity
IPZ55_RS21685	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IPZ55_RS21690	COG1309	transcriptional regulator
IPZ55_RS21700	COG1946	Acyl-CoA thioesterase
IPZ55_RS21720	COG1011	Hydrolase
IPZ55_RS21750	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IPZ55_RS21760	COG3960	tartronate-semialdehyde synthase activity
IPZ55_RS21780	COG1472	Belongs to the glycosyl hydrolase 3 family
IPZ55_RS21785	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IPZ55_RS21830	COG3718	enzyme involved in inositol metabolism
IPZ55_RS21835	COG3962	Belongs to the TPP enzyme family
IPZ55_RS21850	COG1131	(ABC) transporter
IPZ55_RS21880	COG3903	Transcriptional regulator
IPZ55_RS21880	COG3629	intracellular signal transduction
IPZ55_RS21950	COG0629	single-stranded DNA binding
IPZ55_RS21985	COG1136	(ABC) transporter
IPZ55_RS22005	COG0667	Aldo Keto reductase
IPZ55_RS22010	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IPZ55_RS22040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IPZ55_RS22065	COG1486	melibiose metabolic process
IPZ55_RS22075	COG0668	transmembrane transport
IPZ55_RS22090	COG3525	Glycosyl hydrolase, family 20, catalytic domain
IPZ55_RS22110	COG0583	DNA-binding transcription factor activity
IPZ55_RS22160	COG4266	Belongs to the allantoicase family
IPZ55_RS22195	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IPZ55_RS22200	COG0076	glutamate decarboxylase activity
IPZ55_RS22205	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IPZ55_RS22210	COG1113	amino acid transport
IPZ55_RS22215	COG1113	amino acid transport
IPZ55_RS22220	COG1268	BioY protein
IPZ55_RS22225	COG1113	amino acid transport
IPZ55_RS22240	COG4552	Acetyltransferase involved in intracellular survival and related
IPZ55_RS22250	COG0475	glutathione-regulated potassium exporter activity
IPZ55_RS22255	COG3594	Acyltransferase
IPZ55_RS22275	COG0544	peptidyl-prolyl cis-trans isomerase activity
IPZ55_RS22280	COG0740	serine-type endopeptidase activity
IPZ55_RS22285	COG0740	serine-type endopeptidase activity
IPZ55_RS22290	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IPZ55_RS22300	COG0525	valine-tRNA ligase activity
IPZ55_RS22320	COG0105	UTP biosynthetic process
IPZ55_RS22325	COG1077	Cell shape determining protein MreB Mrl
IPZ55_RS22345	COG0772	Belongs to the SEDS family
IPZ55_RS22370	COG1530	ribonuclease E activity
IPZ55_RS22375	COG0261	This protein binds to 23S rRNA in the presence of protein L20
IPZ55_RS22380	COG0211	Belongs to the bacterial ribosomal protein bL27 family
IPZ55_RS22385	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IPZ55_RS22405	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IPZ55_RS22415	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IPZ55_RS22435	COG0501	Belongs to the peptidase M48B family
IPZ55_RS22450	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IPZ55_RS22460	COG0799	negative regulation of ribosome biogenesis
IPZ55_RS22465	COG0588	phosphoglycerate mutase activity
IPZ55_RS22490	COG0495	leucyl-tRNA aminoacylation
IPZ55_RS22500	COG1307	EDD domain protein, DegV family
IPZ55_RS22505	COG1555	photosystem II stabilization
IPZ55_RS22520	COG2353	YceI-like domain
IPZ55_RS22535	COG0268	Binds directly to 16S ribosomal RNA
IPZ55_RS22540	COG0481	GTPase activity
IPZ55_RS22575	COG0484	heat shock protein binding
IPZ55_RS22590	COG0793	Belongs to the peptidase S41A family
IPZ55_RS22590	COG4946	Tricorn protease homolog
IPZ55_RS22595	COG0537	adenosine 5'-monophosphoramidase activity
IPZ55_RS22600	COG1234	tRNA 3'-trailer cleavage
IPZ55_RS22620	COG2515	1-aminocyclopropane-1-carboxylate deaminase
IPZ55_RS22625	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IPZ55_RS22650	COG1486	melibiose metabolic process
IPZ55_RS22655	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IPZ55_RS22690	COG2315	Protein conserved in bacteria
IPZ55_RS22700	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IPZ55_RS22715	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IPZ55_RS22730	COG1381	Involved in DNA repair and RecF pathway recombination
IPZ55_RS22735	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IPZ55_RS22745	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IPZ55_RS22750	COG1121	(ABC) transporter
IPZ55_RS22760	COG0423	glycine-tRNA ligase activity
IPZ55_RS22830	COG0189	ligase activity
IPZ55_RS22840	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IPZ55_RS22855	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IPZ55_RS22860	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
IPZ55_RS22870	COG3467	pyridoxamine 5'-phosphate
IPZ55_RS22895	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
IPZ55_RS22900	COG1846	Transcriptional regulator
IPZ55_RS22900	COG1940	carbohydrate kinase activity
IPZ55_RS22905	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
IPZ55_RS22910	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IPZ55_RS22910	COG0574	Belongs to the PEP-utilizing enzyme family
IPZ55_RS22925	COG1324	tolerance protein
IPZ55_RS22935	COG0829	nickel cation binding
IPZ55_RS22940	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
IPZ55_RS22945	COG0830	nickel cation binding
IPZ55_RS22950	COG0804	urea catabolic process
IPZ55_RS22955	COG0832	Belongs to the urease beta subunit family
IPZ55_RS22965	COG0738	Major facilitator superfamily
IPZ55_RS22985	COG2226	methyltransferase
IPZ55_RS23025	COG1070	Carbohydrate kinase
IPZ55_RS23045	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IPZ55_RS23050	COG0358	DNA primase activity
IPZ55_RS23060	COG3290	protein histidine kinase activity
IPZ55_RS23065	COG4565	transcriptional regulatory protein
IPZ55_RS23070	COG2851	Citrate transporter
IPZ55_RS23080	COG0232	Belongs to the dGTPase family. Type 2 subfamily
IPZ55_RS23100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IPZ55_RS23125	COG1028	Short-chain dehydrogenase reductase Sdr
IPZ55_RS23140	COG2890	protein-(glutamine-N5) methyltransferase activity
IPZ55_RS23155	COG1077	Cell shape determining protein MreB Mrl
IPZ55_RS23180	COG2130	NADP-dependent
IPZ55_RS23185	COG1764	response to oxidative stress
IPZ55_RS23215	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IPZ55_RS23220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IPZ55_RS23225	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IPZ55_RS23240	COG1741	Belongs to the pirin family
IPZ55_RS23255	COG0789	Transcriptional regulator
IPZ55_RS23260	COG0667	Aldo Keto reductase
IPZ55_RS23275	COG2197	response regulator
IPZ55_RS23280	COG4585	Histidine kinase
IPZ55_RS23300	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
IPZ55_RS23345	COG1358	cellular component organization or biogenesis
IPZ55_RS23360	COG0586	Pfam SNARE associated Golgi protein
IPZ55_RS23465	COG3845	ABC transporter
IPZ55_RS23485	COG0438	transferase activity, transferring glycosyl groups
IPZ55_RS23515	COG0477	Major facilitator Superfamily
IPZ55_RS23520	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IPZ55_RS23525	COG1960	acyl-CoA dehydrogenase activity
IPZ55_RS23540	COG2197	response regulator
IPZ55_RS23545	COG0346	lactoylglutathione lyase activity
IPZ55_RS23550	COG4585	Histidine kinase
IPZ55_RS23560	COG1131	(ABC) transporter
IPZ55_RS23575	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IPZ55_RS23590	COG2826	transposase and inactivated derivatives, IS30 family
IPZ55_RS23595	COG0800	Aldolase
IPZ55_RS23600	COG3022	response to hydroperoxide
IPZ55_RS23640	COG1733	regulation of RNA biosynthetic process
IPZ55_RS23660	COG2226	methyltransferase
IPZ55_RS23665	COG0384	phenazine biosynthesis protein PhzF
IPZ55_RS23685	COG0076	glutamate decarboxylase activity
IPZ55_RS23695	COG2814	Major facilitator Superfamily
IPZ55_RS23700	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IPZ55_RS23710	COG1834	amidinotransferase
IPZ55_RS23730	COG1120	ATPase activity
IPZ55_RS23735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPZ55_RS23740	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IPZ55_RS23760	COG5398	heme oxygenase
IPZ55_RS23785	COG1994	Peptidase M50
IPZ55_RS23790	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IPZ55_RS23805	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IPZ55_RS23805	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IPZ55_RS23810	COG2132	Multicopper oxidase
IPZ55_RS23830	COG0174	glutamine synthetase
IPZ55_RS23865	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
IPZ55_RS23880	COG0531	amino acid
IPZ55_RS23885	COG1228	amidohydrolase
IPZ55_RS23900	COG1609	Transcriptional regulator
IPZ55_RS23905	COG2182	Extracellular solute-binding protein
IPZ55_RS23910	COG1175	transmembrane transport
IPZ55_RS23915	COG0395	ABC-type sugar transport system, permease component
IPZ55_RS23920	COG0366	Alpha amylase catalytic
IPZ55_RS23940	COG1309	transcriptional regulator
IPZ55_RS23965	COG0745	RESPONSE REGULATOR receiver
IPZ55_RS23995	COG1012	belongs to the aldehyde dehydrogenase family
IPZ55_RS24060	COG2326	polyphosphate kinase activity
IPZ55_RS24070	COG2376	Dihydroxyacetone kinase
IPZ55_RS24080	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IPZ55_RS24120	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IPZ55_RS24125	COG0321	lipoyl(octanoyl) transferase activity
IPZ55_RS24135	COG0456	acetyltransferase
IPZ55_RS24160	COG4221	oxidoreductase activity
IPZ55_RS24175	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
IPZ55_RS24185	COG0508	dehydrogenase complex catalyzes the overall conversion of
IPZ55_RS24190	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IPZ55_RS24195	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IPZ55_RS24200	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
IPZ55_RS24210	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
IPZ55_RS24255	COG2197	response regulator
IPZ55_RS24260	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IPZ55_RS24265	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IPZ55_RS24290	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IPZ55_RS24295	COG1104	cysteine desulfurase activity
IPZ55_RS24300	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IPZ55_RS24305	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IPZ55_RS24315	COG1376	ErfK ybiS ycfS ynhG family protein
IPZ55_RS24325	COG1845	cytochrome c oxidase, subunit III
IPZ55_RS24330	COG2010	Cytochrome c
IPZ55_RS24335	COG0723	plastoquinol--plastocyanin reductase activity
IPZ55_RS24340	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IPZ55_RS24345	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IPZ55_RS24350	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IPZ55_RS24355	COG1929	Belongs to the glycerate kinase type-1 family
IPZ55_RS24365	COG0745	RESPONSE REGULATOR receiver
IPZ55_RS24370	COG5002	protein histidine kinase activity
IPZ55_RS24385	COG0705	Rhomboid family
IPZ55_RS24420	COG0438	transferase activity, transferring glycosyl groups
IPZ55_RS24440	COG0003	Pfam Anion-transporting ATPase
IPZ55_RS24450	COG1940	carbohydrate kinase activity
IPZ55_RS24475	COG4585	Histidine kinase
IPZ55_RS24480	COG2197	response regulator
IPZ55_RS24485	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IPZ55_RS24495	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
IPZ55_RS24500	COG0243	molybdopterin cofactor binding
IPZ55_RS24505	COG2193	ferroxidase activity
IPZ55_RS24510	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IPZ55_RS24515	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IPZ55_RS24520	COG0515	serine threonine protein kinase
IPZ55_RS24520	COG2815	serine threonine protein kinase
IPZ55_RS24525	COG2022	thiamine diphosphate biosynthetic process
IPZ55_RS24535	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IPZ55_RS24535	COG2022	thiamine diphosphate biosynthetic process
IPZ55_RS24540	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IPZ55_RS24550	COG0352	thiamine-phosphate diphosphorylase activity
IPZ55_RS24570	COG1309	transcriptional regulator
IPZ55_RS24585	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IPZ55_RS24605	COG0714	Associated with various cellular activities
IPZ55_RS24615	COG0275	rRNA processing
IPZ55_RS24630	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IPZ55_RS24640	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IPZ55_RS24645	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IPZ55_RS24655	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IPZ55_RS24660	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IPZ55_RS24665	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IPZ55_RS24670	COG1496	oxidoreductase activity
IPZ55_RS24680	COG1799	cell septum assembly
IPZ55_RS24690	COG3599	regulation of cell shape
IPZ55_RS24700	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IPZ55_RS24710	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IPZ55_RS24720	COG2153	protein acetylation
IPZ55_RS24735	COG0515	serine threonine protein kinase
IPZ55_RS24755	COG0587	DNA-directed DNA polymerase activity
IPZ55_RS24765	COG1432	Conserved Protein
IPZ55_RS24785	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IPZ55_RS24805	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IPZ55_RS24810	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IPZ55_RS24815	COG0131	Imidazoleglycerol-phosphate dehydratase
IPZ55_RS24825	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IPZ55_RS24830	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IPZ55_RS24840	COG0107	imidazoleglycerol-phosphate synthase activity
IPZ55_RS24845	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IPZ55_RS24855	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IPZ55_RS24885	COG0134	indole-3-glycerol-phosphate synthase activity
IPZ55_RS24890	COG0133	tryptophan synthase activity
IPZ55_RS24895	COG0159	tryptophan synthase activity
IPZ55_RS24905	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IPZ55_RS24915	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IPZ55_RS24920	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IPZ55_RS24940	COG1397	ADP-ribosylglycohydrolase
IPZ55_RS24950	COG0069	glutamate synthase activity
IPZ55_RS24950	COG0070	glutamate synthase
IPZ55_RS24950	COG0067	glutamate synthase
IPZ55_RS24965	COG1278	Cold shock
IPZ55_RS24970	COG0513	Belongs to the DEAD box helicase family
IPZ55_RS24980	COG0287	Prephenate dehydrogenase
IPZ55_RS24980	COG1605	Chorismate mutase
IPZ55_RS25010	COG3486	L-lysine 6-monooxygenase (NADPH) activity
IPZ55_RS25015	COG0737	Belongs to the 5'-nucleotidase family
IPZ55_RS25055	COG0559	Belongs to the binding-protein-dependent transport system permease family
IPZ55_RS25065	COG2746	aminoglycoside 3-N-acetyltransferase activity
IPZ55_RS25070	COG2050	protein possibly involved in aromatic compounds catabolism
IPZ55_RS25090	COG1643	Atp-dependent helicase
IPZ55_RS25095	COG2226	methyltransferase
IPZ55_RS25115	COG0237	dephospho-CoA kinase activity
IPZ55_RS25140	COG1288	antiporter activity
IPZ55_RS25190	COG0477	Major facilitator Superfamily
IPZ55_RS25200	COG0584	glycerophosphoryl diester phosphodiesterase
IPZ55_RS25210	COG0556	nucleotide-excision repair
IPZ55_RS25230	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
IPZ55_RS25235	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IPZ55_RS25245	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IPZ55_RS25265	COG1660	Displays ATPase and GTPase activities
IPZ55_RS25275	COG1481	regulation of sporulation
IPZ55_RS25280	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IPZ55_RS25285	COG0126	phosphoglycerate kinase activity
IPZ55_RS25290	COG0149	triose-phosphate isomerase activity
IPZ55_RS25295	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IPZ55_RS25305	COG0166	Belongs to the GPI family
IPZ55_RS25310	COG0363	glucosamine-6-phosphate deaminase activity
IPZ55_RS25325	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IPZ55_RS25330	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IPZ55_RS25335	COG0109	protoheme IX farnesyltransferase activity
IPZ55_RS25350	COG1612	heme a metabolic process
IPZ55_RS25360	COG1131	(ABC) transporter
IPZ55_RS25375	COG0719	Fe-S assembly protein
IPZ55_RS25385	COG0396	ATPase activity
IPZ55_RS25390	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IPZ55_RS25395	COG0822	iron-sulfur transferase activity
IPZ55_RS25405	COG2171	N-acyltransferase activity
IPZ55_RS25445	COG2197	response regulator
IPZ55_RS25450	COG4585	Histidine kinase
IPZ55_RS25480	COG1902	pentaerythritol trinitrate reductase activity
IPZ55_RS25485	COG5285	phytanoyl-CoA dioxygenase
IPZ55_RS25490	COG1917	Cupin 2, conserved barrel domain protein
IPZ55_RS25500	COG0456	acetyltransferase
IPZ55_RS25505	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IPZ55_RS25535	COG1797	cobyrinic acid a,c-diamide synthase activity
IPZ55_RS25550	COG1492	cobalamin metabolic process
IPZ55_RS25570	COG0235	Class ii aldolase
IPZ55_RS25590	COG0488	(ABC) transporter
IPZ55_RS25600	COG1024	Enoyl-CoA hydratase
IPZ55_RS25645	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IPZ55_RS25680	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IPZ55_RS25685	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IPZ55_RS25695	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
IPZ55_RS25715	COG2261	transglycosylase associated protein
IPZ55_RS25720	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IPZ55_RS25730	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IPZ55_RS25740	COG2186	Transcriptional regulator
IPZ55_RS25745	COG2807	transmembrane transport
IPZ55_RS25760	COG0560	Phosphoserine phosphatase
IPZ55_RS25760	COG3830	Belongs to the UPF0237 family
IPZ55_RS25765	COG0842	Transport permease protein
IPZ55_RS25765	COG1131	(ABC) transporter
IPZ55_RS25765	COG1716	ATPase activity
IPZ55_RS25775	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IPZ55_RS25790	COG2197	response regulator
IPZ55_RS25805	COG1119	ATPase activity
IPZ55_RS25825	COG1881	PFAM PEBP family protein
IPZ55_RS25835	COG2094	Belongs to the DNA glycosylase MPG family
IPZ55_RS25870	COG0647	UMP catabolic process
IPZ55_RS25890	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IPZ55_RS25895	COG0497	DNA recombination
IPZ55_RS25910	COG0297	glycogen (starch) synthase activity
IPZ55_RS25915	COG3896	Chloramphenicol phosphotransferase-like protein
IPZ55_RS25930	COG3387	PFAM Glycoside hydrolase 15-related
IPZ55_RS25935	COG0504	CTP synthase activity
IPZ55_RS25940	COG0494	nUDIX hydrolase
IPZ55_RS25950	COG0686	Belongs to the AlaDH PNT family
IPZ55_RS25965	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IPZ55_RS25970	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IPZ55_RS25975	COG1187	pseudouridine synthase activity
IPZ55_RS25985	COG1397	ADP-ribosylglycohydrolase
IPZ55_RS25990	COG3541	Predicted nucleotidyltransferase
IPZ55_RS26005	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
IPZ55_RS26015	COG1160	GTP binding
IPZ55_RS26035	COG0438	transferase activity, transferring glycosyl groups
IPZ55_RS26055	COG0671	phosphoesterase, PA-phosphatase related
IPZ55_RS26065	COG0477	Major facilitator Superfamily
IPZ55_RS26070	COG1799	cell septum assembly
IPZ55_RS26085	COG0765	amino acid transport
IPZ55_RS26095	COG0765	amino acid transport
IPZ55_RS26100	COG1126	abc transporter atp-binding protein
IPZ55_RS26110	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IPZ55_RS26130	COG0330	HflC and HflK could
IPZ55_RS26145	COG0587	DNA-directed DNA polymerase activity
IPZ55_RS26225	COG1216	Glycosyl transferase, family 2
IPZ55_RS26250	COG2755	lipolytic protein G-D-S-L family
IPZ55_RS26270	COG3973	AAA domain
IPZ55_RS26275	COG2188	Transcriptional regulator
IPZ55_RS26280	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
IPZ55_RS26305	COG1309	transcriptional regulator
IPZ55_RS26350	COG3876	Protein conserved in bacteria
IPZ55_RS26360	COG0488	(ABC) transporter
IPZ55_RS26375	COG0318	PFAM AMP-dependent synthetase and ligase
IPZ55_RS26385	COG1960	acyl-CoA dehydrogenase activity
IPZ55_RS26405	COG2149	membrane
IPZ55_RS26410	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
IPZ55_RS26450	COG3265	gluconokinase activity
IPZ55_RS26460	COG3012	SEC-C Motif Domain Protein
IPZ55_RS26465	COG3189	MarR family transcriptional regulator
IPZ55_RS26475	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IPZ55_RS26510	COG0667	Aldo Keto reductase
IPZ55_RS26515	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IPZ55_RS26525	COG0598	Magnesium transport protein CorA
IPZ55_RS26545	COG0215	cysteine-tRNA ligase activity
IPZ55_RS26560	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IPZ55_RS26565	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IPZ55_RS26570	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IPZ55_RS26580	COG1410	methionine synthase
IPZ55_RS26580	COG0646	methionine synthase
IPZ55_RS26590	COG0747	negative chemotaxis
IPZ55_RS26595	COG2197	response regulator
IPZ55_RS26605	COG1994	Peptidase M50
IPZ55_RS26605	COG0517	IMP dehydrogenase activity
IPZ55_RS26625	COG1222	aaa ATPase
IPZ55_RS26630	COG4122	O-methyltransferase activity
IPZ55_RS26640	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
IPZ55_RS26645	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
IPZ55_RS26660	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
IPZ55_RS26695	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IPZ55_RS26700	COG0805	protein transport
IPZ55_RS26715	COG2124	cytochrome p450
IPZ55_RS26745	COG0564	pseudouridine synthase activity
IPZ55_RS26755	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IPZ55_RS26765	COG1595	DNA-templated transcription, initiation
IPZ55_RS26775	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IPZ55_RS26780	COG4175	Glycine betaine
IPZ55_RS26780	COG0517	IMP dehydrogenase activity
IPZ55_RS26805	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IPZ55_RS26810	COG0531	amino acid
IPZ55_RS26815	COG2186	Transcriptional regulator
IPZ55_RS26820	COG0174	glutamine synthetase
IPZ55_RS26825	COG1012	belongs to the aldehyde dehydrogenase family
IPZ55_RS26860	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IPZ55_RS26870	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IPZ55_RS26875	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IPZ55_RS26880	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IPZ55_RS26885	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IPZ55_RS26890	COG5002	protein histidine kinase activity
IPZ55_RS26895	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IPZ55_RS26900	COG0072	phenylalanine-tRNA ligase activity
IPZ55_RS26900	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IPZ55_RS26930	COG0697	spore germination
IPZ55_RS26935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IPZ55_RS26960	COG3547	Transposase (IS116 IS110 IS902 family)
IPZ55_RS26980	COG2838	Isocitrate dehydrogenase
IPZ55_RS26995	COG1309	transcriptional regulator
IPZ55_RS27010	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IPZ55_RS27050	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IPZ55_RS27055	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IPZ55_RS27060	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IPZ55_RS27065	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IPZ55_RS27070	COG1438	arginine binding
IPZ55_RS27075	COG4585	Histidine kinase
IPZ55_RS27080	COG2197	response regulator
IPZ55_RS27090	COG2409	Drug exporters of the RND superfamily
IPZ55_RS27095	COG0385	Bile acid
IPZ55_RS27125	COG0477	Major facilitator Superfamily
IPZ55_RS27130	COG0318	PFAM AMP-dependent synthetase and ligase
IPZ55_RS27130	COG0204	Acyl-transferase
IPZ55_RS27135	COG0584	glycerophosphoryl diester phosphodiesterase
IPZ55_RS27160	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IPZ55_RS27165	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IPZ55_RS27170	COG2011	ABC-type metal ion transport system permease component
IPZ55_RS27175	COG1464	Belongs to the NlpA lipoprotein family
IPZ55_RS27180	COG1464	Belongs to the NlpA lipoprotein family
IPZ55_RS27195	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
IPZ55_RS27200	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IPZ55_RS27200	COG1648	precorrin-2 dehydrogenase activity
IPZ55_RS27275	COG0456	acetyltransferase
IPZ55_RS27335	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IPZ55_RS27340	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IPZ55_RS27355	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IPZ55_RS27360	COG1560	Kdo2-lipid A biosynthetic process
IPZ55_RS27365	COG0438	transferase activity, transferring glycosyl groups
IPZ55_RS27375	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
IPZ55_RS27380	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
IPZ55_RS27385	COG0217	transcriptional regulatory protein
IPZ55_RS27390	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
IPZ55_RS27395	COG0632	four-way junction helicase activity
IPZ55_RS27400	COG2255	four-way junction helicase activity
IPZ55_RS27410	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IPZ55_RS27415	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IPZ55_RS27420	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IPZ55_RS27430	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IPZ55_RS27440	COG1196	nuclear chromosome segregation
IPZ55_RS27445	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IPZ55_RS27455	COG0124	histidyl-tRNA synthetase
IPZ55_RS27470	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IPZ55_RS27485	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IPZ55_RS27490	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IPZ55_RS27495	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IPZ55_RS27500	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IPZ55_RS27505	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IPZ55_RS27510	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IPZ55_RS27515	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IPZ55_RS27525	COG0006	proline dipeptidase activity
IPZ55_RS27530	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IPZ55_RS27535	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IPZ55_RS27545	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IPZ55_RS27550	COG0540	Belongs to the ATCase OTCase family
IPZ55_RS27555	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IPZ55_RS27565	COG0505	Belongs to the CarA family
IPZ55_RS27570	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IPZ55_RS27575	COG0167	dihydroorotate dehydrogenase activity
IPZ55_RS27580	COG0284	orotidine-5'-phosphate decarboxylase activity
IPZ55_RS27595	COG1758	RNA polymerase activity
IPZ55_RS27605	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IPZ55_RS27640	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IPZ55_RS27660	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IPZ55_RS27665	COG2390	Transcriptional regulator
IPZ55_RS27705	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IPZ55_RS27725	COG0697	spore germination
IPZ55_RS27730	COG2233	PERMEase
IPZ55_RS27740	COG0738	Major facilitator superfamily
IPZ55_RS27745	COG1940	carbohydrate kinase activity
IPZ55_RS27745	COG1846	Transcriptional regulator
IPZ55_RS27750	COG1090	epimerase
IPZ55_RS27765	COG3201	nicotinamide mononucleotide transporter
IPZ55_RS27770	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IPZ55_RS27770	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IPZ55_RS27775	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
IPZ55_RS27780	COG0140	phosphoribosyl-ATP diphosphatase activity
IPZ55_RS27785	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IPZ55_RS27815	COG1960	acyl-CoA dehydrogenase activity
IPZ55_RS27840	COG0463	Glycosyl transferase, family 2
IPZ55_RS27845	COG3030	protein affecting phage T7 exclusion by the F plasmid
IPZ55_RS27855	COG2270	Major facilitator Superfamily
IPZ55_RS27865	COG2364	Membrane
IPZ55_RS27870	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IPZ55_RS27955	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
IPZ55_RS27975	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IPZ55_RS27985	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IPZ55_RS28015	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IPZ55_RS28035	COG1716	ATPase activity
IPZ55_RS28055	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IPZ55_RS28065	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IPZ55_RS28065	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IPZ55_RS28100	COG1185	polyribonucleotide nucleotidyltransferase activity
IPZ55_RS28120	COG0697	spore germination
IPZ55_RS28135	COG0697	spore germination
IPZ55_RS28155	COG4251	negative regulation of phosphorylation
IPZ55_RS28165	COG0154	amidase activity
IPZ55_RS28205	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IPZ55_RS28235	COG0815	Transfers the fatty acyl group on membrane lipoproteins
IPZ55_RS28250	COG2826	transposase and inactivated derivatives, IS30 family
IPZ55_RS28260	COG1982	Orn Lys Arg decarboxylase major
IPZ55_RS28270	COG1968	undecaprenyl-diphosphatase activity
IPZ55_RS28290	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IPZ55_RS28350	COG0110	maltose O-acetyltransferase activity
IPZ55_RS28360	COG1832	CoA-binding protein
IPZ55_RS28365	COG1739	Uncharacterized protein family UPF0029
IPZ55_RS28385	COG1595	DNA-templated transcription, initiation
IPZ55_RS28400	COG0420	3'-5' exonuclease activity
IPZ55_RS28405	COG0419	ATPase involved in DNA repair
IPZ55_RS28410	COG1522	sequence-specific DNA binding
IPZ55_RS28420	COG1028	Short-chain dehydrogenase reductase Sdr
IPZ55_RS28435	COG0626	cystathionine gamma-synthase activity
IPZ55_RS28460	COG2188	Transcriptional regulator
IPZ55_RS28465	COG1940	carbohydrate kinase activity
IPZ55_RS28480	COG3663	DNA glycosylase
IPZ55_RS28485	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IPZ55_RS28505	COG0456	acetyltransferase
IPZ55_RS28510	COG0488	(ABC) transporter
IPZ55_RS28515	COG0488	(ABC) transporter
IPZ55_RS28525	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IPZ55_RS28530	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IPZ55_RS28535	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IPZ55_RS28560	COG0791	NLP P60 protein
IPZ55_RS28575	COG0831	urea catabolic process
IPZ55_RS28580	COG0832	Belongs to the urease beta subunit family
IPZ55_RS28585	COG0804	urea catabolic process
IPZ55_RS28595	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
IPZ55_RS28600	COG0829	nickel cation binding
IPZ55_RS28605	COG4552	Acetyltransferase involved in intracellular survival and related
IPZ55_RS28610	COG0204	Acyl-transferase
IPZ55_RS28640	COG1132	(ABC) transporter
IPZ55_RS28655	COG2175	clavaminate synthase activity
IPZ55_RS28665	COG0435	Glutathione S-transferase
IPZ55_RS28670	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
IPZ55_RS28670	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
IPZ55_RS28675	COG1132	(ABC) transporter
IPZ55_RS28680	COG2208	phosphoserine phosphatase activity
IPZ55_RS28680	COG2770	Histidine kinase
IPZ55_RS28695	COG0205	6-phosphofructokinase activity
IPZ55_RS28700	COG3442	glutamine amidotransferase
IPZ55_RS28710	COG0242	peptide deformylase activity
IPZ55_RS28720	COG1960	acyl-CoA dehydrogenase activity
IPZ55_RS28740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IPZ55_RS28765	COG1175	transmembrane transport
IPZ55_RS28770	COG0395	ABC-type sugar transport system, permease component
IPZ55_RS28775	COG2723	6-phospho-beta-galactosidase activity
IPZ55_RS28780	COG0501	Belongs to the peptidase M48B family
IPZ55_RS28825	COG4251	negative regulation of phosphorylation
IPZ55_RS28830	COG0784	Response regulator, receiver
IPZ55_RS28850	COG0656	L-ascorbic acid biosynthetic process
IPZ55_RS28860	COG1595	DNA-templated transcription, initiation
IPZ55_RS28870	COG1132	(ABC) transporter
IPZ55_RS28890	COG0697	spore germination
IPZ55_RS28895	COG0546	phosphoglycolate phosphatase activity
IPZ55_RS28900	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IPZ55_RS28910	COG2313	pseudouridylate synthase activity
IPZ55_RS28915	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IPZ55_RS28950	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IPZ55_RS28955	COG3279	Response regulator of the LytR AlgR family
IPZ55_RS28965	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IPZ55_RS28970	COG3275	phosphorelay sensor kinase activity
IPZ55_RS29035	COG0583	DNA-binding transcription factor activity
IPZ55_RS29045	COG1053	succinate dehydrogenase
IPZ55_RS29050	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IPZ55_RS29055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IPZ55_RS29065	COG3360	Dodecin
IPZ55_RS29070	COG2182	Extracellular solute-binding protein
IPZ55_RS29075	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
IPZ55_RS29080	COG0121	glutamine amidotransferase
IPZ55_RS29085	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IPZ55_RS29105	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IPZ55_RS29110	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IPZ55_RS29130	COG2837	iron assimilation
IPZ55_RS29140	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
IPZ55_RS29140	COG1796	DNA polymerase
IPZ55_RS29145	COG0142	geranyltranstransferase activity
IPZ55_RS29175	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
IPZ55_RS29200	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IPZ55_RS29210	COG0254	rRNA binding
IPZ55_RS29215	COG0267	Belongs to the bacterial ribosomal protein bL33 family
IPZ55_RS29220	COG0227	Belongs to the bacterial ribosomal protein bL28 family
IPZ55_RS29225	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IPZ55_RS29255	COG0477	Major facilitator Superfamily
IPZ55_RS29285	COG3119	arylsulfatase activity
IPZ55_RS29300	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IPZ55_RS29305	COG4948	Mandelate Racemase Muconate Lactonizing
IPZ55_RS29415	COG3655	Transcriptional regulator
IPZ55_RS29425	COG4257	antibiotic catabolic process
IPZ55_RS29435	COG0803	Belongs to the bacterial solute-binding protein 9 family
IPZ55_RS29445	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IPZ55_RS29450	COG1121	(ABC) transporter
IPZ55_RS29455	COG0590	tRNA wobble adenosine to inosine editing
IPZ55_RS29460	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IPZ55_RS29490	COG2201	protein-glutamate methylesterase activity
IPZ55_RS29495	COG0300	oxidoreductase activity
IPZ55_RS29505	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IPZ55_RS29540	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
IPZ55_RS29545	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
IPZ55_RS29550	COG1984	allophanate hydrolase subunit 2
IPZ55_RS29570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPZ55_RS29580	COG1120	ATPase activity
IPZ55_RS29610	COG1132	(ABC) transporter
IPZ55_RS29615	COG1132	(ABC) transporter
IPZ55_RS29620	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IPZ55_RS29630	COG0110	maltose O-acetyltransferase activity
IPZ55_RS29645	COG0242	peptide deformylase activity
IPZ55_RS29665	COG1349	DNA-binding transcription factor activity
IPZ55_RS29680	COG3395	kinase activity
IPZ55_RS29685	COG0235	Class ii aldolase
IPZ55_RS29705	COG1028	Short-chain dehydrogenase reductase Sdr
IPZ55_RS29725	COG1174	glycine betaine transport
IPZ55_RS29730	COG1174	glycine betaine transport
IPZ55_RS29740	COG0517	IMP dehydrogenase activity
IPZ55_RS29740	COG1125	glycine betaine transport
IPZ55_RS29765	COG1960	acyl-CoA dehydrogenase activity
IPZ55_RS29770	COG1960	acyl-CoA dehydrogenase activity
IPZ55_RS29780	COG0601	transmembrane transport
IPZ55_RS29785	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IPZ55_RS29790	COG0444	Belongs to the ABC transporter superfamily
IPZ55_RS29795	COG1124	(ABC) transporter
IPZ55_RS29805	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
IPZ55_RS29810	COG2318	DinB family
IPZ55_RS29835	COG0277	FAD linked oxidase domain protein
IPZ55_RS29840	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IPZ55_RS29850	COG2814	Major facilitator Superfamily
IPZ55_RS29900	COG1028	Short-chain dehydrogenase reductase Sdr
IPZ55_RS29910	COG0142	geranyltranstransferase activity
IPZ55_RS29950	COG3321	synthase
IPZ55_RS29950	COG0604	alcohol dehydrogenase
IPZ55_RS29995	COG0604	alcohol dehydrogenase
IPZ55_RS29995	COG3321	synthase
IPZ55_RS30015	COG2124	cytochrome p450
IPZ55_RS30020	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IPZ55_RS30055	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IPZ55_RS30065	COG1129	ABC transporter
IPZ55_RS30095	COG3483	tryptophan 2,3-dioxygenase activity
IPZ55_RS30100	COG1028	Short-chain dehydrogenase reductase Sdr
IPZ55_RS30105	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IPZ55_RS30110	COG2151	metal-sulfur cluster biosynthetic enzyme
IPZ55_RS30115	COG3396	Phenylacetate-CoA oxygenase
IPZ55_RS30125	COG3396	Phenylacetate-CoA oxygenase
IPZ55_RS30140	COG0604	alcohol dehydrogenase
IPZ55_RS30150	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IPZ55_RS30210	COG0515	serine threonine protein kinase
IPZ55_RS30245	COG1404	Belongs to the peptidase S8 family
IPZ55_RS30290	COG4221	oxidoreductase activity
IPZ55_RS30290	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IPZ55_RS30290	COG0300	oxidoreductase activity
IPZ55_RS30290	COG3321	synthase
IPZ55_RS30300	COG3321	synthase
IPZ55_RS30300	COG0604	alcohol dehydrogenase
IPZ55_RS30305	COG4335	DNA alkylation repair
IPZ55_RS30330	COG0477	Major facilitator Superfamily
IPZ55_RS30360	COG3246	L-lysine catabolic process to acetate
IPZ55_RS30365	COG1250	3-hydroxyacyl-CoA dehydrogenase