locus-tag	class	description
EES41_RS00080	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EES41_RS00085	COG2226	methyltransferase
EES41_RS00120	COG2814	Major facilitator Superfamily
EES41_RS00125	COG2910	NAD(P)H-binding
EES41_RS00135	COG1733	regulation of RNA biosynthetic process
EES41_RS00150	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EES41_RS00180	COG0500	methyltransferase
EES41_RS00415	COG1309	transcriptional regulator
EES41_RS00435	COG2801	Transposase and inactivated derivatives
EES41_RS00440	COG3387	PFAM Glycoside hydrolase 15-related
EES41_RS00450	COG1028	Short-chain dehydrogenase reductase Sdr
EES41_RS00470	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EES41_RS00510	COG3391	amine dehydrogenase activity
EES41_RS00525	COG1309	transcriptional regulator
EES41_RS00530	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EES41_RS00560	COG2318	DinB family
EES41_RS00600	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EES41_RS00780	COG0402	S-adenosylhomocysteine deaminase activity
EES41_RS00790	COG0222	ribosome binding
EES41_RS00825	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EES41_RS00830	COG1088	dTDP-glucose 4,6-dehydratase activity
EES41_RS00835	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EES41_RS00860	COG1309	transcriptional regulator
EES41_RS00900	COG1309	transcriptional regulator
EES41_RS00955	COG1011	Hydrolase
EES41_RS00975	COG0300	oxidoreductase activity
EES41_RS00995	COG0583	DNA-binding transcription factor activity
EES41_RS01005	COG2358	TRAP transporter, solute receptor (TAXI family
EES41_RS01010	COG2205	protein histidine kinase activity
EES41_RS01015	COG0745	RESPONSE REGULATOR receiver
EES41_RS01035	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EES41_RS01040	COG1846	Transcriptional regulator
EES41_RS01060	COG0598	Magnesium transport protein CorA
EES41_RS01120	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EES41_RS01120	COG0517	IMP dehydrogenase activity
EES41_RS01120	COG0617	tRNA 3'-terminal CCA addition
EES41_RS01125	COG0516	GMP reductase activity
EES41_RS01125	COG0517	IMP dehydrogenase activity
EES41_RS01130	COG2239	Acts as a magnesium transporter
EES41_RS01135	COG0516	GMP reductase activity
EES41_RS01135	COG0517	IMP dehydrogenase activity
EES41_RS01190	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EES41_RS01205	COG0516	GMP reductase activity
EES41_RS01205	COG0517	IMP dehydrogenase activity
EES41_RS01240	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EES41_RS01275	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EES41_RS01295	COG0662	Cupin 2, conserved barrel domain protein
EES41_RS01320	COG1278	Cold shock
EES41_RS01325	COG0513	Belongs to the DEAD box helicase family
EES41_RS01365	COG2770	Histidine kinase
EES41_RS01365	COG2208	phosphoserine phosphatase activity
EES41_RS01485	COG2801	Transposase and inactivated derivatives
EES41_RS01485	COG3415	Transposase
EES41_RS01525	COG0698	ribose 5-phosphate isomerase
EES41_RS01550	COG1309	transcriptional regulator
EES41_RS01565	COG0583	DNA-binding transcription factor activity
EES41_RS01575	COG0318	PFAM AMP-dependent synthetase and ligase
EES41_RS01585	COG1309	transcriptional regulator
EES41_RS01590	COG0076	glutamate decarboxylase activity
EES41_RS01620	COG0483	inositol monophosphate 1-phosphatase activity
EES41_RS01625	COG0583	DNA-binding transcription factor activity
EES41_RS01635	COG1028	Short-chain dehydrogenase reductase Sdr
EES41_RS01655	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EES41_RS01660	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EES41_RS01665	COG2890	protein-(glutamine-N5) methyltransferase activity
EES41_RS01675	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EES41_RS01685	COG0431	NADPH-dependent FMN reductase
EES41_RS01730	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EES41_RS01745	COG0596	Alpha beta hydrolase
EES41_RS01750	COG3226	Transcriptional regulator
EES41_RS01795	COG0477	Major facilitator Superfamily
EES41_RS01805	COG0667	Aldo Keto reductase
EES41_RS01815	COG5492	domain, Protein
EES41_RS01815	COG4932	domain protein
EES41_RS01850	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EES41_RS01885	COG0789	Transcriptional regulator
EES41_RS01890	COG1819	glycosyl
EES41_RS01900	COG4221	oxidoreductase activity
EES41_RS01905	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EES41_RS01930	COG0181	hydroxymethylbilane synthase activity
EES41_RS01970	COG0076	glutamate decarboxylase activity
EES41_RS01980	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EES41_RS02010	COG2207	Transcriptional regulator
EES41_RS02010	COG3708	Transcriptional regulator
EES41_RS02025	COG0367	asparagine synthase
EES41_RS02045	COG0702	epimerase
EES41_RS02105	COG2208	phosphoserine phosphatase activity
EES41_RS02105	COG2770	Histidine kinase
EES41_RS02110	COG0596	Alpha beta hydrolase
EES41_RS02165	COG1937	Protein conserved in bacteria
EES41_RS02170	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EES41_RS02180	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EES41_RS02185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EES41_RS02185	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EES41_RS02225	COG1902	pentaerythritol trinitrate reductase activity
EES41_RS02255	COG0477	Major facilitator Superfamily
EES41_RS02285	COG0739	heme binding
EES41_RS02330	COG2508	Transcriptional regulator
EES41_RS02335	COG1725	Transcriptional regulator
EES41_RS02405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EES41_RS02460	COG2045	Belongs to the ComB family
EES41_RS02510	COG1278	Cold shock
EES41_RS02530	COG1132	(ABC) transporter
EES41_RS02540	COG0515	serine threonine protein kinase
EES41_RS02555	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EES41_RS02595	COG2124	cytochrome p450
EES41_RS02625	COG2226	methyltransferase
EES41_RS02680	COG3629	intracellular signal transduction
EES41_RS02680	COG3903	Transcriptional regulator
EES41_RS02700	COG2318	DinB family
EES41_RS02725	COG2376	Dihydroxyacetone kinase
EES41_RS02730	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EES41_RS02735	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EES41_RS02745	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EES41_RS02770	COG2814	Major facilitator Superfamily
EES41_RS02875	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EES41_RS02880	COG3387	PFAM Glycoside hydrolase 15-related
EES41_RS02890	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EES41_RS02910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EES41_RS02960	COG0038	chloride channel
EES41_RS02965	COG0456	acetyltransferase
EES41_RS02970	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EES41_RS02975	COG1917	Cupin 2, conserved barrel domain protein
EES41_RS02980	COG5285	phytanoyl-CoA dioxygenase
EES41_RS02985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EES41_RS02990	COG0765	amino acid transport
EES41_RS02995	COG0765	amino acid transport
EES41_RS03000	COG1126	abc transporter atp-binding protein
EES41_RS03020	COG0659	secondary active sulfate transmembrane transporter activity
EES41_RS03045	COG1012	belongs to the aldehyde dehydrogenase family
EES41_RS03055	COG4175	Glycine betaine
EES41_RS03055	COG3448	diguanylate cyclase activity
EES41_RS03060	COG4176	ABC-type proline glycine betaine transport system permease component
EES41_RS03070	COG3547	Transposase (IS116 IS110 IS902 family)
EES41_RS03090	COG2268	Band 7 protein
EES41_RS03245	COG1316	TRANSCRIPTIONal
EES41_RS03250	COG0640	Transcriptional regulator
EES41_RS03325	COG4221	oxidoreductase activity
EES41_RS03340	COG1113	amino acid transport
EES41_RS03345	COG0515	serine threonine protein kinase
EES41_RS03370	COG2814	Major facilitator Superfamily
EES41_RS03440	COG0673	inositol 2-dehydrogenase activity
EES41_RS03450	COG1476	TRANSCRIPTIONal
EES41_RS03485	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EES41_RS03490	COG2135	peptidase activity
EES41_RS03520	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
EES41_RS03530	COG4941	Belongs to the sigma-70 factor family
EES41_RS03535	COG4585	Histidine kinase
EES41_RS03540	COG2197	response regulator
EES41_RS03565	COG0791	NLP P60 protein
EES41_RS03620	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EES41_RS03635	COG0668	transmembrane transport
EES41_RS03655	COG3903	Transcriptional regulator
EES41_RS03655	COG3629	intracellular signal transduction
EES41_RS03670	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EES41_RS03680	COG0640	Transcriptional regulator
EES41_RS03685	COG0604	alcohol dehydrogenase
EES41_RS03690	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EES41_RS03695	COG2723	6-phospho-beta-galactosidase activity
EES41_RS03705	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EES41_RS03725	COG2208	phosphoserine phosphatase activity
EES41_RS03725	COG2770	Histidine kinase
EES41_RS03735	COG1794	racemase activity, acting on amino acids and derivatives
EES41_RS03760	COG0009	L-threonylcarbamoyladenylate synthase
EES41_RS03790	COG0298	carbon dioxide binding
EES41_RS03795	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
EES41_RS03800	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
EES41_RS03805	COG0375	protein maturation
EES41_RS03845	COG1024	Enoyl-CoA hydratase
EES41_RS03845	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EES41_RS03865	COG0328	RNA-DNA hybrid ribonuclease activity
EES41_RS03875	COG0477	Major facilitator Superfamily
EES41_RS03885	COG1376	ErfK ybiS ycfS ynhG family protein
EES41_RS03890	COG0583	DNA-binding transcription factor activity
EES41_RS03910	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EES41_RS03915	COG4566	intracellular signal transduction
EES41_RS03930	COG3469	chitinase activity
EES41_RS03985	COG2409	Drug exporters of the RND superfamily
EES41_RS04010	COG0308	aminopeptidase N
EES41_RS04030	COG3959	Transketolase, thiamine diphosphate binding domain
EES41_RS04055	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EES41_RS04065	COG3425	synthase
EES41_RS04070	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EES41_RS04070	COG0300	oxidoreductase activity
EES41_RS04070	COG4221	oxidoreductase activity
EES41_RS04070	COG3321	synthase
EES41_RS04075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EES41_RS04125	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EES41_RS04125	COG0318	PFAM AMP-dependent synthetase and ligase
EES41_RS04125	COG3321	synthase
EES41_RS04125	COG0300	oxidoreductase activity
EES41_RS04125	COG1028	Short-chain dehydrogenase reductase Sdr
EES41_RS04130	COG3321	synthase
EES41_RS04130	COG0604	alcohol dehydrogenase
EES41_RS04135	COG1024	Enoyl-CoA hydratase
EES41_RS04140	COG3425	synthase
EES41_RS04145	COG2091	lysine biosynthetic process via aminoadipic acid
EES41_RS04155	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EES41_RS04170	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EES41_RS04180	COG1366	Belongs to the anti-sigma-factor antagonist family
EES41_RS04180	COG2172	sigma factor antagonist activity
EES41_RS04180	COG2208	phosphoserine phosphatase activity
EES41_RS04185	COG1129	ABC transporter
EES41_RS04190	COG1172	Belongs to the binding-protein-dependent transport system permease family
EES41_RS04200	COG2197	response regulator
EES41_RS04260	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EES41_RS04270	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EES41_RS04300	COG1131	(ABC) transporter
EES41_RS04315	COG3321	synthase
EES41_RS04315	COG0604	alcohol dehydrogenase
EES41_RS04320	COG3321	synthase
EES41_RS04320	COG0604	alcohol dehydrogenase
EES41_RS04370	COG0604	alcohol dehydrogenase
EES41_RS04370	COG3321	synthase
EES41_RS04395	COG4585	Histidine kinase
EES41_RS04400	COG2197	response regulator
EES41_RS04435	COG0435	Glutathione S-transferase
EES41_RS04455	COG0577	efflux transmembrane transporter activity
EES41_RS04455	COG1136	(ABC) transporter
EES41_RS04470	COG0318	PFAM AMP-dependent synthetase and ligase
EES41_RS04515	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EES41_RS04515	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EES41_RS04525	COG3486	L-lysine 6-monooxygenase (NADPH) activity
EES41_RS04530	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EES41_RS04545	COG1132	(ABC) transporter
EES41_RS04550	COG1132	(ABC) transporter
EES41_RS04555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EES41_RS04560	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EES41_RS04565	COG1120	ATPase activity
EES41_RS04575	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
EES41_RS04590	COG3387	PFAM Glycoside hydrolase 15-related
EES41_RS04615	COG1271	oxidase subunit
EES41_RS04620	COG1028	Short-chain dehydrogenase reductase Sdr
EES41_RS04625	COG3265	gluconokinase activity
EES41_RS04645	COG0546	phosphoglycolate phosphatase activity
EES41_RS04655	COG2261	transglycosylase associated protein
EES41_RS04665	COG3903	Transcriptional regulator
EES41_RS04665	COG3629	intracellular signal transduction
EES41_RS04700	COG1131	(ABC) transporter
EES41_RS04760	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EES41_RS04795	COG2124	cytochrome p450
EES41_RS04905	COG0346	lactoylglutathione lyase activity
EES41_RS04960	COG0714	Associated with various cellular activities
EES41_RS05005	COG1404	Belongs to the peptidase S8 family
EES41_RS05060	COG2205	protein histidine kinase activity
EES41_RS05070	COG0189	ligase activity
EES41_RS05100	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EES41_RS05105	COG3842	ATPase activity
EES41_RS05125	COG2188	Transcriptional regulator
EES41_RS05145	COG2319	Wd-40 repeat
EES41_RS05145	COG4249	Peptidase C14 caspase catalytic subunit p20
EES41_RS05150	COG1136	(ABC) transporter
EES41_RS05150	COG4591	ABC-type transport system involved in lipoprotein release permease component
EES41_RS05170	COG1136	(ABC) transporter
EES41_RS05180	COG4941	Belongs to the sigma-70 factor family
EES41_RS05200	COG2837	iron assimilation
EES41_RS05215	COG2124	cytochrome p450
EES41_RS05230	COG3759	membrane
EES41_RS05240	COG1278	Cold shock
EES41_RS05245	COG0513	Belongs to the DEAD box helicase family
EES41_RS05295	COG0604	alcohol dehydrogenase
EES41_RS05300	COG2723	6-phospho-beta-galactosidase activity
EES41_RS05305	COG1846	Transcriptional regulator
EES41_RS05305	COG1940	carbohydrate kinase activity
EES41_RS05330	COG1028	Short-chain dehydrogenase reductase Sdr
EES41_RS05355	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EES41_RS05375	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EES41_RS05415	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EES41_RS05480	COG0531	amino acid
EES41_RS05505	COG1053	succinate dehydrogenase
EES41_RS05535	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
EES41_RS05535	COG1672	PFAM Archaeal ATPase
EES41_RS05580	COG2267	carboxylic ester hydrolase activity
EES41_RS05595	COG0318	PFAM AMP-dependent synthetase and ligase
EES41_RS05600	COG2366	antibiotic biosynthetic process
EES41_RS05605	COG0387	Pfam Sodium calcium exchanger
EES41_RS05620	COG2070	2-Nitropropane dioxygenase
EES41_RS05625	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EES41_RS05650	COG0515	serine threonine protein kinase
EES41_RS05650	COG2815	serine threonine protein kinase
EES41_RS05710	COG0640	Transcriptional regulator
EES41_RS05715	COG2226	methyltransferase
EES41_RS05730	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EES41_RS05735	COG0573	inorganic phosphate transmembrane transporter activity
EES41_RS05740	COG0581	inorganic phosphate transmembrane transporter activity
EES41_RS05745	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EES41_RS05750	COG0745	RESPONSE REGULATOR receiver
EES41_RS05765	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EES41_RS05780	COG3118	belongs to the thioredoxin family
EES41_RS05785	COG0492	ferredoxin-NADP+ reductase activity
EES41_RS05790	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EES41_RS05805	COG2072	flavoprotein involved in K transport
EES41_RS05815	COG0798	PFAM Bile acid sodium symporter
EES41_RS05820	COG0640	Transcriptional regulator
EES41_RS05825	COG2072	flavoprotein involved in K transport
EES41_RS05855	COG1960	acyl-CoA dehydrogenase activity
EES41_RS05870	COG1349	DNA-binding transcription factor activity
EES41_RS05880	COG0156	8-amino-7-oxononanoate synthase activity
EES41_RS05885	COG1063	alcohol dehydrogenase
EES41_RS05905	COG0477	Major facilitator Superfamily
EES41_RS05925	COG3387	PFAM Glycoside hydrolase 15-related
EES41_RS05930	COG2259	Doxx family
EES41_RS05955	COG1461	Dihydroxyacetone kinase
EES41_RS05975	COG0725	ABC transporter, periplasmic molybdate-binding protein
EES41_RS06015	COG0596	Alpha beta hydrolase
EES41_RS06020	COG0702	epimerase
EES41_RS06025	COG1309	transcriptional regulator
EES41_RS06030	COG2815	serine threonine protein kinase
EES41_RS06030	COG0515	serine threonine protein kinase
EES41_RS06040	COG0842	Transport permease protein
EES41_RS06040	COG1131	(ABC) transporter
EES41_RS06040	COG1716	ATPase activity
EES41_RS06080	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EES41_RS06115	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EES41_RS06120	COG1215	transferase activity, transferring glycosyl groups
EES41_RS06165	COG1940	carbohydrate kinase activity
EES41_RS06200	COG0445	tRNA wobble uridine modification
EES41_RS06210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EES41_RS06260	COG0330	HflC and HflK could
EES41_RS06280	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EES41_RS06280	COG4651	solute:proton antiporter activity
EES41_RS06315	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EES41_RS06380	COG3387	PFAM Glycoside hydrolase 15-related
EES41_RS06410	COG2226	methyltransferase
EES41_RS06420	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EES41_RS06445	COG0009	L-threonylcarbamoyladenylate synthase
EES41_RS06460	COG1278	Cold shock
EES41_RS06485	COG2358	TRAP transporter, solute receptor (TAXI family
EES41_RS06490	COG2205	protein histidine kinase activity
EES41_RS06495	COG0745	RESPONSE REGULATOR receiver
EES41_RS06585	COG0438	transferase activity, transferring glycosyl groups
EES41_RS06590	COG1316	TRANSCRIPTIONal
EES41_RS06705	COG1316	TRANSCRIPTIONal
EES41_RS06775	COG0330	HflC and HflK could
EES41_RS06840	COG1595	DNA-templated transcription, initiation
EES41_RS06850	COG2226	methyltransferase
EES41_RS06865	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EES41_RS06910	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EES41_RS06970	COG3547	Transposase (IS116 IS110 IS902 family)
EES41_RS07005	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EES41_RS07060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EES41_RS07070	COG0584	glycerophosphoryl diester phosphodiesterase
EES41_RS07090	COG0671	phosphoesterase, PA-phosphatase related
EES41_RS07100	COG1309	transcriptional regulator
EES41_RS07130	COG0640	Transcriptional regulator
EES41_RS07135	COG1902	pentaerythritol trinitrate reductase activity
EES41_RS07150	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EES41_RS07165	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EES41_RS07185	COG1309	transcriptional regulator
EES41_RS07210	COG4221	oxidoreductase activity
EES41_RS07220	COG0446	pyridine nucleotide-disulphide oxidoreductase
EES41_RS07220	COG1902	pentaerythritol trinitrate reductase activity
EES41_RS07225	COG2267	carboxylic ester hydrolase activity
EES41_RS07235	COG0395	ABC-type sugar transport system, permease component
EES41_RS07240	COG1175	transmembrane transport
EES41_RS07265	COG3345	alpha-galactosidase
EES41_RS07280	COG0142	geranyltranstransferase activity
EES41_RS07315	COG0583	DNA-binding transcription factor activity
EES41_RS07320	COG0604	alcohol dehydrogenase
EES41_RS07320	COG3321	synthase
EES41_RS07335	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EES41_RS07345	COG4106	trans-aconitate 2-methyltransferase activity
EES41_RS07355	COG3511	phospholipase C
EES41_RS07365	COG1024	Enoyl-CoA hydratase
EES41_RS07370	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EES41_RS07380	COG2223	nitrite transmembrane transporter activity
EES41_RS07385	COG1335	isochorismatase
EES41_RS07405	COG2226	methyltransferase
EES41_RS07410	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EES41_RS07435	COG2205	protein histidine kinase activity
EES41_RS07505	COG0346	lactoylglutathione lyase activity
EES41_RS07510	COG1556	Lactate utilization protein
EES41_RS07515	COG1139	Iron-sulfur cluster binding protein
EES41_RS07520	COG0247	lactate metabolic process
EES41_RS07530	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EES41_RS07550	COG2838	Isocitrate dehydrogenase
EES41_RS07555	COG3152	Membrane
EES41_RS07570	COG0598	Magnesium transport protein CorA
EES41_RS07590	COG0583	DNA-binding transcription factor activity
EES41_RS07595	COG0697	spore germination
EES41_RS07625	COG1695	Transcriptional regulator
EES41_RS07655	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EES41_RS07655	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EES41_RS07690	COG1716	ATPase activity
EES41_RS07710	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EES41_RS07740	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EES41_RS07750	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EES41_RS07765	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
EES41_RS07780	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EES41_RS07795	COG2018	Roadblock/LC7 domain
EES41_RS07825	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EES41_RS07830	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EES41_RS07835	COG1984	allophanate hydrolase subunit 2
EES41_RS07875	COG2270	Major facilitator Superfamily
EES41_RS07890	COG0463	Glycosyl transferase, family 2
EES41_RS07925	COG1960	acyl-CoA dehydrogenase activity
EES41_RS07930	COG1309	transcriptional regulator
EES41_RS07950	COG0572	uridine kinase
EES41_RS07975	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EES41_RS07980	COG0140	phosphoribosyl-ATP diphosphatase activity
EES41_RS07985	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EES41_RS07990	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EES41_RS07990	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EES41_RS07995	COG3201	nicotinamide mononucleotide transporter
EES41_RS08020	COG1940	carbohydrate kinase activity
EES41_RS08020	COG1846	Transcriptional regulator
EES41_RS08025	COG0738	Major facilitator superfamily
EES41_RS08030	COG2233	PERMEase
EES41_RS08045	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EES41_RS08075	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EES41_RS08090	COG0531	amino acid
EES41_RS08095	COG2755	lipolytic protein G-D-S-L family
EES41_RS08125	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EES41_RS08130	COG3275	phosphorelay sensor kinase activity
EES41_RS08150	COG3548	integral membrane protein
EES41_RS08205	COG1012	belongs to the aldehyde dehydrogenase family
EES41_RS08215	COG3206	protein involved in exopolysaccharide biosynthesis
EES41_RS08215	COG0489	protein tyrosine kinase activity
EES41_RS08220	COG2208	phosphoserine phosphatase activity
EES41_RS08220	COG2770	Histidine kinase
EES41_RS08240	COG1366	Belongs to the anti-sigma-factor antagonist family
EES41_RS08255	COG0693	protein deglycase activity
EES41_RS08260	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
EES41_RS08280	COG0028	Belongs to the TPP enzyme family
EES41_RS08295	COG0492	ferredoxin-NADP+ reductase activity
EES41_RS08310	COG2346	COG2346, Truncated hemoglobins
EES41_RS08330	COG2390	Transcriptional regulator
EES41_RS08335	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EES41_RS08350	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EES41_RS08365	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EES41_RS08380	COG0194	GDP metabolic process
EES41_RS08390	COG0284	orotidine-5'-phosphate decarboxylase activity
EES41_RS08395	COG0167	dihydroorotate dehydrogenase activity
EES41_RS08400	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EES41_RS08405	COG0505	Belongs to the CarA family
EES41_RS08415	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EES41_RS08420	COG0540	Belongs to the ATCase OTCase family
EES41_RS08425	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EES41_RS08435	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EES41_RS08440	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EES41_RS08445	COG0006	proline dipeptidase activity
EES41_RS08455	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EES41_RS08460	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EES41_RS08465	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EES41_RS08470	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EES41_RS08480	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EES41_RS08485	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EES41_RS08495	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EES41_RS08500	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EES41_RS08520	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EES41_RS08545	COG0124	histidyl-tRNA synthetase
EES41_RS08555	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EES41_RS08560	COG1196	nuclear chromosome segregation
EES41_RS08565	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EES41_RS08570	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EES41_RS08575	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EES41_RS08580	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EES41_RS08590	COG2255	four-way junction helicase activity
EES41_RS08595	COG0632	four-way junction helicase activity
EES41_RS08600	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EES41_RS08605	COG0217	transcriptional regulatory protein
EES41_RS08610	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EES41_RS08615	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EES41_RS08625	COG0438	transferase activity, transferring glycosyl groups
EES41_RS08630	COG1560	Kdo2-lipid A biosynthetic process
EES41_RS08635	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EES41_RS08655	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EES41_RS08660	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EES41_RS08665	COG0456	acetyltransferase
EES41_RS08680	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EES41_RS08735	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EES41_RS08790	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EES41_RS08790	COG1648	precorrin-2 dehydrogenase activity
EES41_RS08795	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EES41_RS08810	COG1464	Belongs to the NlpA lipoprotein family
EES41_RS08815	COG2011	ABC-type metal ion transport system permease component
EES41_RS08820	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EES41_RS08850	COG0204	Acyl-transferase
EES41_RS08850	COG0318	PFAM AMP-dependent synthetase and ligase
EES41_RS08860	COG0477	Major facilitator Superfamily
EES41_RS08880	COG0165	Argininosuccinate lyase
EES41_RS08885	COG0137	argininosuccinate synthase activity
EES41_RS08905	COG1438	arginine binding
EES41_RS08910	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EES41_RS08915	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EES41_RS08920	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EES41_RS08925	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EES41_RS08945	COG0697	spore germination
EES41_RS08955	COG1649	PFAM Uncharacterised BCR, COG1649
EES41_RS08975	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EES41_RS08975	COG0072	phenylalanine-tRNA ligase activity
EES41_RS08980	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EES41_RS08985	COG5002	protein histidine kinase activity
EES41_RS08990	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EES41_RS08995	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EES41_RS09000	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EES41_RS09005	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EES41_RS09045	COG1028	Short-chain dehydrogenase reductase Sdr
EES41_RS09050	COG1012	belongs to the aldehyde dehydrogenase family
EES41_RS09055	COG0174	glutamine synthetase
EES41_RS09065	COG1113	amino acid transport
EES41_RS09070	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EES41_RS09085	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EES41_RS09095	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EES41_RS09110	COG0564	pseudouridine synthase activity
EES41_RS09125	COG0805	protein transport
EES41_RS09130	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EES41_RS09165	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
EES41_RS09175	COG1609	Transcriptional regulator
EES41_RS09180	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
EES41_RS09185	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
EES41_RS09200	COG4122	O-methyltransferase activity
EES41_RS09205	COG1222	aaa ATPase
EES41_RS09230	COG1994	Peptidase M50
EES41_RS09230	COG0517	IMP dehydrogenase activity
EES41_RS09240	COG2197	response regulator
EES41_RS09260	COG1410	methionine synthase
EES41_RS09260	COG0646	methionine synthase
EES41_RS09265	COG1414	Transcriptional regulator
EES41_RS09270	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EES41_RS09275	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EES41_RS09280	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EES41_RS09290	COG0215	cysteine-tRNA ligase activity
EES41_RS09310	COG0598	Magnesium transport protein CorA
EES41_RS09320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EES41_RS09325	COG0667	Aldo Keto reductase
EES41_RS09355	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EES41_RS09365	COG1113	amino acid transport
EES41_RS09390	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EES41_RS09395	COG2149	membrane
EES41_RS09410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EES41_RS09420	COG1960	acyl-CoA dehydrogenase activity
EES41_RS09435	COG0318	PFAM AMP-dependent synthetase and ligase
EES41_RS09440	COG1028	Short-chain dehydrogenase reductase Sdr
EES41_RS09445	COG3876	Protein conserved in bacteria
EES41_RS09485	COG1960	acyl-CoA dehydrogenase activity
EES41_RS09505	COG2851	Citrate transporter
EES41_RS09510	COG3383	formate dehydrogenase (NAD+) activity
EES41_RS09515	COG1309	transcriptional regulator
EES41_RS09535	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
EES41_RS09540	COG2188	Transcriptional regulator
EES41_RS09575	COG0515	serine threonine protein kinase
EES41_RS09575	COG2815	serine threonine protein kinase
EES41_RS09585	COG2755	lipolytic protein G-D-S-L family
EES41_RS09595	COG4044	May play a role in the intracellular transport of hydrophobic ligands
EES41_RS09600	COG1725	Transcriptional regulator
EES41_RS09635	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EES41_RS09640	COG0587	DNA-directed DNA polymerase activity
EES41_RS09665	COG0641	radical SAM
EES41_RS09710	COG1799	cell septum assembly
EES41_RS09715	COG1960	acyl-CoA dehydrogenase activity
EES41_RS09720	COG0477	Major facilitator Superfamily
EES41_RS09730	COG0671	phosphoesterase, PA-phosphatase related
EES41_RS09755	COG1160	GTP binding
EES41_RS09765	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EES41_RS09815	COG1187	pseudouridine synthase activity
EES41_RS09820	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EES41_RS09825	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EES41_RS09840	COG0686	Belongs to the AlaDH PNT family
EES41_RS09850	COG0494	nUDIX hydrolase
EES41_RS09855	COG0504	CTP synthase activity
EES41_RS09860	COG3387	PFAM Glycoside hydrolase 15-related
EES41_RS09890	COG0438	transferase activity, transferring glycosyl groups
EES41_RS09895	COG0497	DNA recombination
EES41_RS09900	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EES41_RS09920	COG1120	ATPase activity
EES41_RS09925	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EES41_RS09930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EES41_RS09935	COG0647	UMP catabolic process
EES41_RS09970	COG2094	Belongs to the DNA glycosylase MPG family
EES41_RS09980	COG1881	PFAM PEBP family protein
EES41_RS10005	COG1119	ATPase activity
EES41_RS10020	COG2197	response regulator
EES41_RS10025	COG4585	Histidine kinase
EES41_RS10035	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EES41_RS10045	COG0842	Transport permease protein
EES41_RS10045	COG1716	ATPase activity
EES41_RS10045	COG1131	(ABC) transporter
EES41_RS10050	COG0560	Phosphoserine phosphatase
EES41_RS10050	COG3830	Belongs to the UPF0237 family
EES41_RS10070	COG2186	Transcriptional regulator
EES41_RS10080	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EES41_RS10085	COG1028	Short-chain dehydrogenase reductase Sdr
EES41_RS10100	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EES41_RS10120	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EES41_RS10125	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EES41_RS10135	COG1404	Belongs to the peptidase S8 family
EES41_RS10140	COG1063	alcohol dehydrogenase
EES41_RS10165	COG0300	oxidoreductase activity
EES41_RS10180	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EES41_RS10195	COG1028	Short-chain dehydrogenase reductase Sdr
EES41_RS10220	COG1302	Protein conserved in bacteria
EES41_RS10230	COG1024	Enoyl-CoA hydratase
EES41_RS10240	COG0488	(ABC) transporter
EES41_RS10275	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
EES41_RS10280	COG1492	cobalamin metabolic process
EES41_RS10295	COG1797	cobyrinic acid a,c-diamide synthase activity
EES41_RS10325	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EES41_RS10330	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EES41_RS10350	COG2197	response regulator
EES41_RS10355	COG4585	Histidine kinase
EES41_RS10405	COG2171	N-acyltransferase activity
EES41_RS10420	COG3226	Transcriptional regulator
EES41_RS10425	COG2076	Multidrug Resistance protein
EES41_RS10435	COG2151	metal-sulfur cluster biosynthetic enzyme
EES41_RS10440	COG0822	iron-sulfur transferase activity
EES41_RS10445	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EES41_RS10450	COG0396	ATPase activity
EES41_RS10460	COG0719	Fe-S assembly protein
EES41_RS10490	COG1612	heme a metabolic process
EES41_RS10505	COG0109	protoheme IX farnesyltransferase activity
EES41_RS10515	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EES41_RS10530	COG0363	glucosamine-6-phosphate deaminase activity
EES41_RS10535	COG0166	Belongs to the GPI family
EES41_RS10545	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EES41_RS10550	COG0149	triose-phosphate isomerase activity
EES41_RS10555	COG0126	phosphoglycerate kinase activity
EES41_RS10560	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EES41_RS10570	COG1481	regulation of sporulation
EES41_RS10580	COG1660	Displays ATPase and GTPase activities
EES41_RS10585	COG0322	excinuclease ABC activity
EES41_RS10615	COG3547	Transposase (IS116 IS110 IS902 family)
EES41_RS10620	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EES41_RS10630	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EES41_RS10655	COG0556	nucleotide-excision repair
EES41_RS10660	COG0584	glycerophosphoryl diester phosphodiesterase
EES41_RS10665	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EES41_RS10680	COG2313	pseudouridylate synthase activity
EES41_RS10720	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EES41_RS10735	COG0237	dephospho-CoA kinase activity
EES41_RS10745	COG0539	negative regulation of cytoplasmic translation
EES41_RS10750	COG2226	methyltransferase
EES41_RS10755	COG1643	Atp-dependent helicase
EES41_RS10795	COG2050	protein possibly involved in aromatic compounds catabolism
EES41_RS10810	COG0559	Belongs to the binding-protein-dependent transport system permease family
EES41_RS10855	COG0737	Belongs to the 5'-nucleotidase family
EES41_RS10880	COG0287	Prephenate dehydrogenase
EES41_RS10880	COG1605	Chorismate mutase
EES41_RS10895	COG1028	Short-chain dehydrogenase reductase Sdr
EES41_RS10905	COG1024	Enoyl-CoA hydratase
EES41_RS10925	COG2365	Tyrosine phosphatase family
EES41_RS10935	COG1278	Cold shock
EES41_RS10940	COG0183	Belongs to the thiolase family
EES41_RS10945	COG1309	transcriptional regulator
EES41_RS10950	COG1028	Short-chain dehydrogenase reductase Sdr
EES41_RS10955	COG1960	acyl-CoA dehydrogenase activity
EES41_RS10960	COG1960	acyl-CoA dehydrogenase activity
EES41_RS11025	COG0494	nUDIX hydrolase
EES41_RS11050	COG0069	glutamate synthase activity
EES41_RS11050	COG0070	glutamate synthase
EES41_RS11050	COG0067	glutamate synthase
EES41_RS11060	COG1397	ADP-ribosylglycohydrolase
EES41_RS11080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EES41_RS11085	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EES41_RS11095	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EES41_RS11105	COG0159	tryptophan synthase activity
EES41_RS11110	COG0133	tryptophan synthase activity
EES41_RS11120	COG0134	indole-3-glycerol-phosphate synthase activity
EES41_RS11145	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EES41_RS11160	COG0107	imidazoleglycerol-phosphate synthase activity
EES41_RS11165	COG0251	oxidation-reduction process
EES41_RS11170	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EES41_RS11175	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EES41_RS11180	COG0131	Imidazoleglycerol-phosphate dehydratase
EES41_RS11185	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EES41_RS11190	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EES41_RS11205	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EES41_RS11225	COG1432	Conserved Protein
EES41_RS11230	COG0587	DNA-directed DNA polymerase activity
EES41_RS11285	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EES41_RS11295	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EES41_RS11300	COG3599	regulation of cell shape
EES41_RS11310	COG1799	cell septum assembly
EES41_RS11325	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EES41_RS11335	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EES41_RS11340	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EES41_RS11350	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EES41_RS11355	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EES41_RS11365	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EES41_RS11370	COG0768	penicillin binding
EES41_RS11380	COG0275	rRNA processing
EES41_RS11390	COG0714	Associated with various cellular activities
EES41_RS11405	COG1309	transcriptional regulator
EES41_RS11415	COG4133	protoheme IX ABC transporter activity
EES41_RS11425	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EES41_RS11440	COG1233	COG1233 Phytoene dehydrogenase and related
EES41_RS11455	COG0352	thiamine-phosphate diphosphorylase activity
EES41_RS11470	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EES41_RS11470	COG2022	thiamine diphosphate biosynthetic process
EES41_RS11480	COG2022	thiamine diphosphate biosynthetic process
EES41_RS11485	COG0515	serine threonine protein kinase
EES41_RS11485	COG2815	serine threonine protein kinase
EES41_RS11490	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EES41_RS11500	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EES41_RS11505	COG2193	ferroxidase activity
EES41_RS11515	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
EES41_RS11530	COG0205	6-phosphofructokinase activity
EES41_RS11535	COG2197	response regulator
EES41_RS11540	COG4585	Histidine kinase
EES41_RS11565	COG1940	carbohydrate kinase activity
EES41_RS11575	COG0003	Pfam Anion-transporting ATPase
EES41_RS11600	COG0438	transferase activity, transferring glycosyl groups
EES41_RS11640	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EES41_RS11645	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EES41_RS11650	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EES41_RS11655	COG0723	plastoquinol--plastocyanin reductase activity
EES41_RS11660	COG2010	Cytochrome c
EES41_RS11665	COG1845	cytochrome c oxidase, subunit III
EES41_RS11675	COG1376	ErfK ybiS ycfS ynhG family protein
EES41_RS11685	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EES41_RS11690	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EES41_RS11700	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EES41_RS11720	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EES41_RS11730	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EES41_RS11735	COG2197	response regulator
EES41_RS11740	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
EES41_RS11765	COG2226	methyltransferase
EES41_RS11780	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EES41_RS11785	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EES41_RS11785	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EES41_RS11795	COG4585	Histidine kinase
EES41_RS11825	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EES41_RS11830	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EES41_RS11835	COG0508	dehydrogenase complex catalyzes the overall conversion of
EES41_RS11860	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
EES41_RS11900	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EES41_RS11905	COG0321	lipoyl(octanoyl) transferase activity
EES41_RS11965	COG0745	RESPONSE REGULATOR receiver
EES41_RS11985	COG2365	Tyrosine phosphatase family
EES41_RS12035	COG0366	Alpha amylase catalytic
EES41_RS12040	COG3833	ABC-type maltose transport systems, permease component
EES41_RS12045	COG1175	transmembrane transport
EES41_RS12055	COG0366	Alpha amylase catalytic
EES41_RS12060	COG1609	Transcriptional regulator
EES41_RS12075	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EES41_RS12090	COG0174	glutamine synthetase
EES41_RS12105	COG0174	glutamine synthetase
EES41_RS12130	COG2267	carboxylic ester hydrolase activity
EES41_RS12145	COG2132	Multicopper oxidase
EES41_RS12165	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EES41_RS12185	COG1994	Peptidase M50
EES41_RS12245	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EES41_RS12250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EES41_RS12255	COG1120	ATPase activity
EES41_RS12265	COG2837	iron assimilation
EES41_RS12270	COG0672	)-iron permease
EES41_RS12280	COG0384	phenazine biosynthesis protein PhzF
EES41_RS12285	COG1028	Short-chain dehydrogenase reductase Sdr
EES41_RS12290	COG2814	Major facilitator Superfamily
EES41_RS12300	COG1834	amidinotransferase
EES41_RS12315	COG3022	response to hydroperoxide
EES41_RS12320	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
EES41_RS12340	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EES41_RS12350	COG1028	Short-chain dehydrogenase reductase Sdr
EES41_RS12360	COG2030	dehydratase
EES41_RS12370	COG0183	Belongs to the thiolase family
EES41_RS12375	COG1960	acyl-CoA dehydrogenase activity
EES41_RS12390	COG0860	N-Acetylmuramoyl-L-alanine amidase
EES41_RS12400	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EES41_RS12425	COG0438	transferase activity, transferring glycosyl groups
EES41_RS12430	COG1309	transcriptional regulator
EES41_RS12465	COG3845	ABC transporter
EES41_RS12480	COG0183	Belongs to the thiolase family
EES41_RS12485	COG2124	cytochrome p450
EES41_RS12520	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EES41_RS12525	COG2318	DinB family
EES41_RS12615	COG1358	cellular component organization or biogenesis
EES41_RS12665	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
EES41_RS12670	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EES41_RS12680	COG0477	Major facilitator Superfamily
EES41_RS12685	COG1309	transcriptional regulator
EES41_RS12700	COG0667	Aldo Keto reductase
EES41_RS12705	COG0789	Transcriptional regulator
EES41_RS12730	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EES41_RS12735	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EES41_RS12740	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EES41_RS12770	COG1764	response to oxidative stress
EES41_RS12775	COG2130	NADP-dependent
EES41_RS12800	COG1077	Cell shape determining protein MreB Mrl
EES41_RS12820	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EES41_RS12820	COG0825	malonyl-CoA metabolic process
EES41_RS12830	COG0477	Major facilitator Superfamily
EES41_RS12835	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
EES41_RS12860	COG1070	Carbohydrate kinase
EES41_RS12880	COG2949	membrane
EES41_RS12890	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EES41_RS12900	COG0358	DNA primase activity
EES41_RS12930	COG1017	nitric oxide dioxygenase activity
EES41_RS12930	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EES41_RS12935	COG2146	nitrite reductase [NAD(P)H] activity
EES41_RS12935	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EES41_RS12960	COG0574	Belongs to the PEP-utilizing enzyme family
EES41_RS12960	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EES41_RS12985	COG0667	Aldo Keto reductase
EES41_RS12990	COG1309	transcriptional regulator
EES41_RS13000	COG0423	glycine-tRNA ligase activity
EES41_RS13005	COG3443	Belongs to the bacterial solute-binding protein 9 family
EES41_RS13005	COG0803	Belongs to the bacterial solute-binding protein 9 family
EES41_RS13010	COG1121	(ABC) transporter
EES41_RS13015	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EES41_RS13030	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EES41_RS13035	COG1381	Involved in DNA repair and RecF pathway recombination
EES41_RS13040	COG2233	PERMEase
EES41_RS13050	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EES41_RS13075	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EES41_RS13105	COG2315	Protein conserved in bacteria
EES41_RS13115	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EES41_RS13125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EES41_RS13130	COG1234	tRNA 3'-trailer cleavage
EES41_RS13135	COG0537	adenosine 5'-monophosphoramidase activity
EES41_RS13145	COG2070	2-Nitropropane dioxygenase
EES41_RS13150	COG0484	heat shock protein binding
EES41_RS13155	COG1420	regulation of RNA biosynthetic process
EES41_RS13180	COG0481	GTPase activity
EES41_RS13185	COG0268	Binds directly to 16S ribosomal RNA
EES41_RS13205	COG2353	YceI-like domain
EES41_RS13215	COG1596	polysaccharide export
EES41_RS13215	COG1555	photosystem II stabilization
EES41_RS13220	COG1307	EDD domain protein, DegV family
EES41_RS13230	COG0495	leucyl-tRNA aminoacylation
EES41_RS13250	COG0588	phosphoglycerate mutase activity
EES41_RS13255	COG0799	negative regulation of ribosome biogenesis
EES41_RS13265	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EES41_RS13270	COG0501	Belongs to the peptidase M48B family
EES41_RS13285	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EES41_RS13295	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EES41_RS13305	COG0463	Glycosyl transferase, family 2
EES41_RS13310	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EES41_RS13315	COG0438	transferase activity, transferring glycosyl groups
EES41_RS13330	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EES41_RS13335	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EES41_RS13340	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EES41_RS13345	COG1530	ribonuclease E activity
EES41_RS13365	COG0772	Belongs to the SEDS family
EES41_RS13370	COG0768	penicillin binding
EES41_RS13385	COG1077	Cell shape determining protein MreB Mrl
EES41_RS13390	COG0105	UTP biosynthetic process
EES41_RS13400	COG0285	dihydrofolate synthase activity
EES41_RS13405	COG1077	Cell shape determining protein MreB Mrl
EES41_RS13410	COG4585	Histidine kinase
EES41_RS13415	COG0525	valine-tRNA ligase activity
EES41_RS13425	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EES41_RS13430	COG0740	serine-type endopeptidase activity
EES41_RS13435	COG0740	serine-type endopeptidase activity
EES41_RS13440	COG0544	peptidyl-prolyl cis-trans isomerase activity
EES41_RS13475	COG1660	Displays ATPase and GTPase activities
EES41_RS13485	COG4552	Acetyltransferase involved in intracellular survival and related
EES41_RS13495	COG0698	ribose 5-phosphate isomerase
EES41_RS13500	COG1113	amino acid transport
EES41_RS13505	COG1268	BioY protein
EES41_RS13510	COG1113	amino acid transport
EES41_RS13515	COG1113	amino acid transport
EES41_RS13520	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EES41_RS13525	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EES41_RS13575	COG0583	DNA-binding transcription factor activity
EES41_RS13585	COG0697	spore germination
EES41_RS13595	COG1846	Transcriptional regulator
EES41_RS13625	COG0668	transmembrane transport
EES41_RS13635	COG1653	transport
EES41_RS13640	COG1175	transmembrane transport
EES41_RS13645	COG0395	ABC-type sugar transport system, permease component
EES41_RS13650	COG1486	melibiose metabolic process
EES41_RS13665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EES41_RS13675	COG0515	serine threonine protein kinase
EES41_RS13695	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EES41_RS13700	COG2346	COG2346, Truncated hemoglobins
EES41_RS13730	COG0629	single-stranded DNA binding
EES41_RS13795	COG3962	Belongs to the TPP enzyme family
EES41_RS13800	COG3718	enzyme involved in inositol metabolism
EES41_RS13815	COG0673	inositol 2-dehydrogenase activity
EES41_RS13825	COG2409	Drug exporters of the RND superfamily
EES41_RS13850	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EES41_RS13865	COG0697	spore germination
EES41_RS13875	COG1472	Belongs to the glycosyl hydrolase 3 family
EES41_RS13930	COG1946	Acyl-CoA thioesterase
EES41_RS13955	COG1309	transcriptional regulator
EES41_RS13960	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EES41_RS13975	COG1960	acyl-CoA dehydrogenase activity
EES41_RS13985	COG2375	cellular response to nickel ion
EES41_RS13990	COG0076	glutamate decarboxylase activity
EES41_RS13995	COG3486	L-lysine 6-monooxygenase (NADPH) activity
EES41_RS14025	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EES41_RS14035	COG0589	response to stress
EES41_RS14045	COG4977	sequence-specific DNA binding
EES41_RS14050	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EES41_RS14075	COG0395	ABC-type sugar transport system, permease component
EES41_RS14100	COG0745	RESPONSE REGULATOR receiver
EES41_RS14110	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EES41_RS14125	COG0406	alpha-ribazole phosphatase activity
EES41_RS14185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EES41_RS14205	COG0318	PFAM AMP-dependent synthetase and ligase
EES41_RS14275	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EES41_RS14280	COG2188	Transcriptional regulator
EES41_RS14290	COG1940	carbohydrate kinase activity
EES41_RS14295	COG0673	inositol 2-dehydrogenase activity
EES41_RS14305	COG0706	membrane insertase activity
EES41_RS14315	COG3764	Sortase (surface protein transpeptidase)
EES41_RS14345	COG2801	Transposase and inactivated derivatives
EES41_RS14345	COG3415	Transposase
EES41_RS14350	COG2733	membrane
EES41_RS14375	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EES41_RS14415	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EES41_RS14425	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EES41_RS14430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EES41_RS14435	COG1263	PTS System
EES41_RS14440	COG1263	PTS System
EES41_RS14445	COG1234	tRNA 3'-trailer cleavage
EES41_RS14455	COG3189	MarR family transcriptional regulator
EES41_RS14475	COG1113	amino acid transport
EES41_RS14485	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EES41_RS14495	COG1335	isochorismatase
EES41_RS14530	COG0277	FAD linked oxidase domain protein
EES41_RS14540	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EES41_RS14640	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EES41_RS14650	COG1678	Uncharacterized ACR, COG1678
EES41_RS14655	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EES41_RS14660	COG0776	regulation of translation
EES41_RS14670	COG3973	AAA domain
EES41_RS14680	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EES41_RS14695	COG0583	DNA-binding transcription factor activity
EES41_RS14720	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EES41_RS14725	COG0793	Belongs to the peptidase S41A family
EES41_RS14735	COG2884	Cell division ATP-binding protein ftsE
EES41_RS14745	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EES41_RS14755	COG0515	serine threonine protein kinase
EES41_RS14760	COG0515	serine threonine protein kinase
EES41_RS14770	COG1653	transport
EES41_RS14775	COG1175	transmembrane transport
EES41_RS14780	COG0395	ABC-type sugar transport system, permease component
EES41_RS14785	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EES41_RS14800	COG1134	teichoic acid transport
EES41_RS14800	COG1388	LysM domain
EES41_RS14805	COG2902	Dehydrogenase
EES41_RS14810	COG0546	phosphoglycolate phosphatase activity
EES41_RS14825	COG0653	protein targeting
EES41_RS14840	COG2197	response regulator
EES41_RS14845	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EES41_RS14855	COG0823	Involved in the tonB-independent uptake of proteins
EES41_RS14860	COG5002	protein histidine kinase activity
EES41_RS14860	COG5000	phosphorelay sensor kinase activity
EES41_RS14865	COG0745	RESPONSE REGULATOR receiver
EES41_RS14885	COG0714	Associated with various cellular activities
EES41_RS14925	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EES41_RS14935	COG1482	cell wall glycoprotein biosynthetic process
EES41_RS14945	COG2835	tetraacyldisaccharide 4'-kinase activity
EES41_RS14950	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EES41_RS14985	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EES41_RS14990	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
EES41_RS14990	COG0778	Nitroreductase
EES41_RS15010	COG1316	TRANSCRIPTIONal
EES41_RS15035	COG1607	acyl-coa hydrolase
EES41_RS15040	COG1316	TRANSCRIPTIONal
EES41_RS15045	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EES41_RS15075	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EES41_RS15100	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EES41_RS15115	COG2205	protein histidine kinase activity
EES41_RS15120	COG0745	RESPONSE REGULATOR receiver
EES41_RS15125	COG3104	oligopeptide transport
EES41_RS15150	COG1228	amidohydrolase
EES41_RS15160	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EES41_RS15165	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EES41_RS15190	COG2755	lipolytic protein G-D-S-L family
EES41_RS15195	COG0183	Belongs to the thiolase family
EES41_RS15225	COG1136	(ABC) transporter
EES41_RS15230	COG0577	efflux transmembrane transporter activity
EES41_RS15235	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EES41_RS15240	COG1252	NADH dehydrogenase
EES41_RS15265	COG0148	phosphopyruvate hydratase activity
EES41_RS15280	COG2124	cytochrome p450
EES41_RS15285	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EES41_RS15285	COG1017	nitric oxide dioxygenase activity
EES41_RS15340	COG0577	efflux transmembrane transporter activity
EES41_RS15345	COG1136	(ABC) transporter
EES41_RS15350	COG2814	Major facilitator Superfamily
EES41_RS15365	COG0596	Alpha beta hydrolase
EES41_RS15395	COG4585	Histidine kinase
EES41_RS15405	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EES41_RS15410	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EES41_RS15415	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EES41_RS15420	COG0193	aminoacyl-tRNA hydrolase activity
EES41_RS15425	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EES41_RS15435	COG1309	transcriptional regulator
EES41_RS15445	COG4106	trans-aconitate 2-methyltransferase activity
EES41_RS15450	COG1846	Transcriptional regulator
EES41_RS15455	COG2197	response regulator
EES41_RS15485	COG0488	(ABC) transporter
EES41_RS15495	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EES41_RS15500	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EES41_RS15505	COG3583	domain protein
EES41_RS15505	COG3584	3D domain protein
EES41_RS15510	COG0084	hydrolase, TatD family'
EES41_RS15540	COG1122	ATPase activity
EES41_RS15550	COG0310	cobalt ion transport
EES41_RS15560	COG2409	Drug exporters of the RND superfamily
EES41_RS15570	COG4946	Tricorn protease homolog
EES41_RS15570	COG0793	Belongs to the peptidase S41A family
EES41_RS15580	COG1028	Short-chain dehydrogenase reductase Sdr
EES41_RS15585	COG2267	carboxylic ester hydrolase activity
EES41_RS15590	COG2072	flavoprotein involved in K transport
EES41_RS15620	COG2423	ornithine cyclodeaminase activity
EES41_RS15625	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EES41_RS15630	COG4569	acetaldehyde dehydrogenase (acetylating) activity
EES41_RS15640	COG0156	8-amino-7-oxononanoate synthase activity
EES41_RS15655	COG0006	proline dipeptidase activity
EES41_RS15675	COG0521	Mo-molybdopterin cofactor biosynthetic process
EES41_RS15675	COG0315	cyclic pyranopterin monophosphate synthase activity
EES41_RS15680	COG0315	cyclic pyranopterin monophosphate synthase activity
EES41_RS15690	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EES41_RS15695	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EES41_RS15705	COG3263	regulation of cellular component size
EES41_RS15720	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EES41_RS15730	COG1970	mechanosensitive ion channel activity
EES41_RS15810	COG0728	peptidoglycan biosynthetic process
EES41_RS15820	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EES41_RS15825	COG0438	transferase activity, transferring glycosyl groups
EES41_RS15880	COG0477	Major facilitator Superfamily
EES41_RS15940	COG1132	(ABC) transporter
EES41_RS15950	COG3629	intracellular signal transduction
EES41_RS15950	COG3903	Transcriptional regulator
EES41_RS16010	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EES41_RS16025	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EES41_RS16035	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EES41_RS16045	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EES41_RS16050	COG0443	Heat shock 70 kDa protein
EES41_RS16065	COG3903	Transcriptional regulator
EES41_RS16065	COG3629	intracellular signal transduction
EES41_RS16145	COG1686	Belongs to the peptidase S11 family
EES41_RS16180	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
EES41_RS16185	COG2365	Tyrosine phosphatase family
EES41_RS16285	COG0494	nUDIX hydrolase
EES41_RS16360	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EES41_RS16360	COG0515	serine threonine protein kinase
EES41_RS16380	COG1960	acyl-CoA dehydrogenase activity
EES41_RS16410	COG2072	flavoprotein involved in K transport
EES41_RS16420	COG1024	Enoyl-CoA hydratase
EES41_RS16435	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EES41_RS16445	COG1960	acyl-CoA dehydrogenase activity
EES41_RS16450	COG1028	Short-chain dehydrogenase reductase Sdr
EES41_RS16480	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EES41_RS16530	COG1960	acyl-CoA dehydrogenase activity
EES41_RS16535	COG1960	acyl-CoA dehydrogenase activity
EES41_RS16545	COG0318	PFAM AMP-dependent synthetase and ligase
EES41_RS16595	COG1131	(ABC) transporter
EES41_RS16630	COG2130	NADP-dependent
EES41_RS16645	COG2945	thiolester hydrolase activity
EES41_RS16645	COG0596	Alpha beta hydrolase
EES41_RS16655	COG4821	SIS domain
EES41_RS16665	COG0259	pyridoxamine-phosphate oxidase activity
EES41_RS16675	COG1309	transcriptional regulator
EES41_RS16695	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EES41_RS16720	COG0247	lactate metabolic process
EES41_RS16720	COG0277	FAD linked oxidase domain protein
EES41_RS16725	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EES41_RS16745	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EES41_RS16755	COG2252	PERMEase
EES41_RS16775	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EES41_RS16780	COG0667	Aldo Keto reductase
EES41_RS16795	COG2268	Band 7 protein
EES41_RS16815	COG2814	Major facilitator Superfamily
EES41_RS16825	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EES41_RS16830	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
EES41_RS16835	COG1278	Cold shock
EES41_RS16865	COG1061	Type III restriction enzyme res subunit
EES41_RS16880	COG3973	AAA domain
EES41_RS16920	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EES41_RS16925	COG1263	PTS System
EES41_RS16925	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EES41_RS16930	COG0135	phosphoribosylanthranilate isomerase activity
EES41_RS16960	COG0463	Glycosyl transferase, family 2
EES41_RS16970	COG0561	phosphatase activity
EES41_RS16970	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EES41_RS16985	COG1940	carbohydrate kinase activity
EES41_RS16990	COG1228	amidohydrolase
EES41_RS17160	COG3842	ATPase activity
EES41_RS17170	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EES41_RS17180	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EES41_RS17185	COG0215	cysteine-tRNA ligase activity
EES41_RS17190	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EES41_RS17195	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EES41_RS17200	COG1329	Transcriptional regulator
EES41_RS17225	COG5002	protein histidine kinase activity
EES41_RS17245	COG0588	phosphoglycerate mutase activity
EES41_RS17260	COG0438	transferase activity, transferring glycosyl groups
EES41_RS17295	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EES41_RS17300	COG2890	protein-(glutamine-N5) methyltransferase activity
EES41_RS17305	COG1595	DNA-templated transcription, initiation
EES41_RS17310	COG4552	Acetyltransferase involved in intracellular survival and related
EES41_RS17320	COG1490	D-aminoacyl-tRNA deacylase activity
EES41_RS17330	COG0735	belongs to the Fur family
EES41_RS17335	COG3485	protocatechuate 3,4-dioxygenase
EES41_RS17395	COG0745	RESPONSE REGULATOR receiver
EES41_RS17400	COG1609	Transcriptional regulator
EES41_RS17410	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EES41_RS17415	COG0745	RESPONSE REGULATOR receiver
EES41_RS17425	COG0823	Involved in the tonB-independent uptake of proteins
EES41_RS17435	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EES41_RS17440	COG0737	Belongs to the 5'-nucleotidase family
EES41_RS17445	COG0456	acetyltransferase
EES41_RS17450	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EES41_RS17480	COG0306	phosphate transporter
EES41_RS17490	COG1937	Protein conserved in bacteria
EES41_RS17515	COG0671	phosphoesterase, PA-phosphatase related
EES41_RS17520	COG0739	heme binding
EES41_RS17520	COG0741	lytic transglycosylase activity
EES41_RS17520	COG1196	nuclear chromosome segregation
EES41_RS17530	COG1280	lysine exporter protein (LysE YggA)
EES41_RS17540	COG1357	PFAM Pentapeptide repeats (8 copies)
EES41_RS17660	COG1252	NADH dehydrogenase
EES41_RS17690	COG0579	oxidoreductase
EES41_RS17695	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EES41_RS17705	COG0741	lytic transglycosylase activity
EES41_RS17705	COG0739	heme binding
EES41_RS17705	COG1196	nuclear chromosome segregation
EES41_RS17730	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EES41_RS17735	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EES41_RS17760	COG0785	Cytochrome C biogenesis protein
EES41_RS17775	COG1643	Atp-dependent helicase
EES41_RS17805	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EES41_RS17815	COG3119	arylsulfatase activity
EES41_RS17830	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EES41_RS17835	COG0047	phosphoribosylformylglycinamidine synthase activity
EES41_RS17840	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EES41_RS17860	COG1131	(ABC) transporter
EES41_RS17870	COG3850	Histidine kinase
EES41_RS17875	COG2197	response regulator
EES41_RS17885	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EES41_RS17900	COG0151	Belongs to the GarS family
EES41_RS17930	COG1309	transcriptional regulator
EES41_RS17940	COG3835	regulator
EES41_RS17945	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
EES41_RS17950	COG2080	2 iron, 2 sulfur cluster binding
EES41_RS17950	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EES41_RS17985	COG0433	COG0433 Predicted ATPase
EES41_RS18000	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EES41_RS18045	COG1191	sigma factor activity
EES41_RS18085	COG2205	protein histidine kinase activity
EES41_RS18090	COG0745	RESPONSE REGULATOR receiver
EES41_RS18135	COG0745	RESPONSE REGULATOR receiver
EES41_RS18145	COG0318	PFAM AMP-dependent synthetase and ligase
EES41_RS18150	COG1595	DNA-templated transcription, initiation
EES41_RS18165	COG1960	acyl-CoA dehydrogenase activity
EES41_RS18175	COG1960	acyl-CoA dehydrogenase activity
EES41_RS18205	COG2855	membrane
EES41_RS18220	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EES41_RS18235	COG0653	protein targeting
EES41_RS18255	COG0006	proline dipeptidase activity
EES41_RS18285	COG2372	response to copper ion
EES41_RS18290	COG2837	iron assimilation
EES41_RS18300	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EES41_RS18305	COG0561	phosphatase activity
EES41_RS18320	COG1131	(ABC) transporter
EES41_RS18345	COG0789	Transcriptional regulator
EES41_RS18355	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
EES41_RS18360	COG0326	Molecular chaperone. Has ATPase activity
EES41_RS18375	COG0561	phosphatase activity
EES41_RS18385	COG4988	ABC transporter
EES41_RS18390	COG1294	oxidase, subunit
EES41_RS18395	COG1271	oxidase subunit
EES41_RS18405	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EES41_RS18410	COG1609	Transcriptional regulator
EES41_RS18425	COG0667	Aldo Keto reductase
EES41_RS18430	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EES41_RS18455	COG0662	Cupin 2, conserved barrel domain protein
EES41_RS18460	COG1950	PFAM Membrane protein of
EES41_RS18465	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EES41_RS18470	COG0626	cystathionine gamma-synthase activity
EES41_RS18500	COG0456	acetyltransferase
EES41_RS18515	COG0305	Participates in initiation and elongation during chromosome replication
EES41_RS18530	COG0359	binds to the 23S rRNA
EES41_RS18535	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EES41_RS18540	COG0629	single-stranded DNA binding
EES41_RS18545	COG0360	Binds together with S18 to 16S ribosomal RNA
EES41_RS18570	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EES41_RS18590	COG0617	tRNA 3'-terminal CCA addition
EES41_RS18610	COG1595	DNA-templated transcription, initiation
EES41_RS18620	COG0492	ferredoxin-NADP+ reductase activity
EES41_RS18625	COG3118	belongs to the thioredoxin family
EES41_RS18640	COG1192	Involved in chromosome partitioning
EES41_RS18645	COG0357	Ribosomal RNA small subunit methyltransferase G
EES41_RS18655	COG0706	membrane insertase activity
EES41_RS18660	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EES41_RS18670	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EES41_RS18675	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EES41_RS18685	COG0592	DNA-directed DNA polymerase activity
EES41_RS18690	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EES41_RS18695	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EES41_RS18700	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
EES41_RS18710	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EES41_RS18735	COG0515	serine threonine protein kinase
EES41_RS18765	COG0705	Rhomboid family
EES41_RS18765	COG0457	Tetratricopeptide repeat
EES41_RS18780	COG3764	Sortase (surface protein transpeptidase)
EES41_RS18790	COG3764	Sortase (surface protein transpeptidase)
EES41_RS18795	COG3764	Sortase (surface protein transpeptidase)
EES41_RS18800	COG0515	serine threonine protein kinase
EES41_RS18815	COG0772	Belongs to the SEDS family
EES41_RS18825	COG1716	ATPase activity
EES41_RS18830	COG1716	ATPase activity
EES41_RS18840	COG4585	Histidine kinase
EES41_RS18845	COG2197	response regulator
EES41_RS18870	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EES41_RS18875	COG2151	metal-sulfur cluster biosynthetic enzyme
EES41_RS18880	COG3396	Phenylacetate-CoA oxygenase
EES41_RS18885	COG3460	Phenylacetate-CoA oxygenase
EES41_RS18890	COG3396	Phenylacetate-CoA oxygenase
EES41_RS18915	COG1250	3-hydroxyacyl-CoA dehydrogenase
EES41_RS18920	COG1309	transcriptional regulator
EES41_RS18925	COG1522	sequence-specific DNA binding
EES41_RS18945	COG0604	alcohol dehydrogenase
EES41_RS18945	COG1028	Short-chain dehydrogenase reductase Sdr
EES41_RS18945	COG3321	synthase
EES41_RS18950	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EES41_RS18960	COG0746	molybdenum cofactor guanylyltransferase activity
EES41_RS18975	COG1136	(ABC) transporter
EES41_RS18975	COG4591	ABC-type transport system involved in lipoprotein release permease component
EES41_RS18990	COG0515	serine threonine protein kinase
EES41_RS18995	COG0515	serine threonine protein kinase
EES41_RS19015	COG0022	dehydrogenase e1 component
EES41_RS19020	COG0508	dehydrogenase complex catalyzes the overall conversion of
EES41_RS19045	COG1028	Short-chain dehydrogenase reductase Sdr
EES41_RS19060	COG1802	Transcriptional regulator
EES41_RS19065	COG2271	Major facilitator Superfamily
EES41_RS19110	COG1362	aminopeptidase activity
EES41_RS19120	COG1960	acyl-CoA dehydrogenase activity
EES41_RS19145	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EES41_RS19150	COG2304	oxidoreductase activity
EES41_RS19160	COG2205	protein histidine kinase activity
EES41_RS19170	COG1289	transmembrane transporter activity
EES41_RS19230	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EES41_RS19235	COG1191	sigma factor activity
EES41_RS19265	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EES41_RS19270	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EES41_RS19275	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EES41_RS19290	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EES41_RS19310	COG1028	Short-chain dehydrogenase reductase Sdr
EES41_RS19320	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EES41_RS19330	COG2264	protein methyltransferase activity
EES41_RS19355	COG2226	methyltransferase
EES41_RS19360	COG2197	response regulator
EES41_RS19470	COG0513	Belongs to the DEAD box helicase family
EES41_RS19475	COG1278	Cold shock
EES41_RS19480	COG2409	Drug exporters of the RND superfamily
EES41_RS19485	COG4585	Histidine kinase
EES41_RS19490	COG2197	response regulator
EES41_RS19525	COG0717	Belongs to the dCTP deaminase family
EES41_RS19555	COG0443	Heat shock 70 kDa protein
EES41_RS19560	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EES41_RS19565	COG0484	heat shock protein binding
EES41_RS19570	COG0789	Transcriptional regulator
EES41_RS19595	COG0542	response to heat
EES41_RS19635	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EES41_RS19650	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EES41_RS19655	COG0191	fructose-bisphosphate aldolase activity
EES41_RS19670	COG3844	kynureninase activity
EES41_RS19715	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EES41_RS19730	COG1131	(ABC) transporter
EES41_RS19735	COG3559	Exporter of polyketide antibiotics
EES41_RS19745	COG2197	response regulator
EES41_RS19755	COG2197	response regulator
EES41_RS19760	COG4585	Histidine kinase
EES41_RS19790	COG0693	protein deglycase activity
EES41_RS19795	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EES41_RS19815	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EES41_RS19820	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EES41_RS19840	COG1595	DNA-templated transcription, initiation
EES41_RS19860	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EES41_RS19870	COG0438	transferase activity, transferring glycosyl groups
EES41_RS19880	COG0438	transferase activity, transferring glycosyl groups
EES41_RS19885	COG0402	S-adenosylhomocysteine deaminase activity
EES41_RS19945	COG0017	Asparaginyl-tRNA synthetase
EES41_RS19960	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EES41_RS19995	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EES41_RS20020	COG1609	Transcriptional regulator
EES41_RS20045	COG1408	metallophosphoesterase
EES41_RS20055	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EES41_RS20070	COG0003	Pfam Anion-transporting ATPase
EES41_RS20095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EES41_RS20130	COG0596	Alpha beta hydrolase
EES41_RS20140	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EES41_RS20145	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EES41_RS20150	COG0288	reversible hydration of carbon dioxide
EES41_RS20210	COG1111	helicase
EES41_RS20210	COG1205	dead DEAH box helicase
EES41_RS20215	COG1366	Belongs to the anti-sigma-factor antagonist family
EES41_RS20220	COG2172	sigma factor antagonist activity
EES41_RS20225	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
EES41_RS20235	COG2890	protein-(glutamine-N5) methyltransferase activity
EES41_RS20245	COG1754	DNA topoisomerase type I activity
EES41_RS20245	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EES41_RS20250	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EES41_RS20255	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EES41_RS20275	COG0477	Major facilitator Superfamily
EES41_RS20280	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EES41_RS20290	COG0456	acetyltransferase
EES41_RS20305	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EES41_RS20305	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EES41_RS20315	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EES41_RS20335	COG1012	belongs to the aldehyde dehydrogenase family
EES41_RS20340	COG2318	DinB family
EES41_RS20345	COG0789	Transcriptional regulator
EES41_RS20350	COG0586	Pfam SNARE associated Golgi protein
EES41_RS20360	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EES41_RS20365	COG2027	D-alanyl-D-alanine carboxypeptidase
EES41_RS20375	COG0037	tRNA processing
EES41_RS20380	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EES41_RS20390	COG0302	gtp cyclohydrolase
EES41_RS20405	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EES41_RS20410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EES41_RS20425	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EES41_RS20425	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EES41_RS20440	COG1174	glycine betaine transport
EES41_RS20450	COG1732	Glycine betaine
EES41_RS20470	COG0649	NAD binding
EES41_RS20550	COG1674	ftsk spoiiie
EES41_RS20565	COG2197	response regulator
EES41_RS20590	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EES41_RS20600	COG2843	Capsule synthesis protein
EES41_RS20610	COG2234	aminopeptidase activity
EES41_RS20640	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EES41_RS20645	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EES41_RS20655	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EES41_RS20690	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EES41_RS20715	COG0739	heme binding
EES41_RS20725	COG2205	protein histidine kinase activity
EES41_RS20730	COG0745	RESPONSE REGULATOR receiver
EES41_RS20740	COG1595	DNA-templated transcription, initiation
EES41_RS20745	COG1194	a g-specific adenine glycosylase
EES41_RS20760	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EES41_RS20780	COG0248	Ppx GppA phosphatase
EES41_RS20785	COG1082	Xylose isomerase domain protein TIM barrel
EES41_RS20795	COG0129	dihydroxy-acid dehydratase activity
EES41_RS20815	COG0842	Transport permease protein
EES41_RS20815	COG1129	ABC transporter
EES41_RS20825	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EES41_RS20830	COG0180	Tryptophanyl-tRNA synthetase
EES41_RS20860	COG0123	including yeast histone deacetylase and acetoin utilization protein
EES41_RS20910	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EES41_RS20915	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EES41_RS20920	COG0181	hydroxymethylbilane synthase activity
EES41_RS20925	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EES41_RS20925	COG1648	precorrin-2 dehydrogenase activity
EES41_RS20930	COG0113	porphobilinogen synthase activity
EES41_RS20970	COG0018	arginyl-trna synthetase
EES41_RS20975	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
EES41_RS20995	COG1690	Belongs to the RtcB family
EES41_RS21010	COG1742	UPF0060 membrane protein
EES41_RS21020	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EES41_RS21035	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EES41_RS21040	COG0406	alpha-ribazole phosphatase activity
EES41_RS21050	COG0785	Cytochrome C biogenesis protein
EES41_RS21055	COG1333	cytochrome c biogenesis protein
EES41_RS21060	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EES41_RS21090	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EES41_RS21115	COG0163	prenyltransferase activity
EES41_RS21125	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
EES41_RS21140	COG1301	dicarboxylic acid transport
EES41_RS21185	COG1278	Cold shock
EES41_RS21190	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
EES41_RS21200	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
EES41_RS21220	COG2226	methyltransferase
EES41_RS21225	COG2066	Belongs to the glutaminase family
EES41_RS21255	COG1136	(ABC) transporter
EES41_RS21255	COG0577	efflux transmembrane transporter activity
EES41_RS21260	COG1136	(ABC) transporter
EES41_RS21295	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EES41_RS21300	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EES41_RS21305	COG0649	NAD binding
EES41_RS21315	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EES41_RS21320	COG1034	ATP synthesis coupled electron transport
EES41_RS21325	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EES41_RS21330	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EES41_RS21335	COG0839	Belongs to the complex I subunit 6 family
EES41_RS21340	COG0713	ATP synthesis coupled electron transport
EES41_RS21345	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EES41_RS21355	COG1007	ATP synthesis coupled electron transport
EES41_RS21370	COG0561	phosphatase activity
EES41_RS21380	COG0142	geranyltranstransferase activity
EES41_RS21410	COG0702	epimerase
EES41_RS21415	COG1733	regulation of RNA biosynthetic process
EES41_RS21420	COG1013	pyruvate-flavodoxin oxidoreductase activity
EES41_RS21425	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EES41_RS21425	COG0674	pyruvate-flavodoxin oxidoreductase activity
EES41_RS21445	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EES41_RS21450	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EES41_RS21455	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EES41_RS21460	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EES41_RS21465	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EES41_RS21470	COG0839	Belongs to the complex I subunit 6 family
EES41_RS21475	COG0713	ATP synthesis coupled electron transport
EES41_RS21480	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EES41_RS21490	COG1007	ATP synthesis coupled electron transport
EES41_RS21495	COG0501	Belongs to the peptidase M48B family
EES41_RS21500	COG3304	Inner membrane component domain
EES41_RS21510	COG0659	secondary active sulfate transmembrane transporter activity
EES41_RS21515	COG1666	GTP binding
EES41_RS21555	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EES41_RS21560	COG2030	dehydratase
EES41_RS21575	COG0477	Major facilitator Superfamily
EES41_RS21580	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EES41_RS21590	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EES41_RS21595	COG0436	Aminotransferase
EES41_RS21605	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EES41_RS21635	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EES41_RS21640	COG0222	ribosome binding
EES41_RS21650	COG0085	RNA polymerase activity
EES41_RS21655	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EES41_RS21695	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EES41_RS21700	COG0049	tRNA binding
EES41_RS21705	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EES41_RS21710	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EES41_RS21720	COG0051	transcription antitermination factor activity, RNA binding
EES41_RS21725	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EES41_RS21730	COG0088	Forms part of the polypeptide exit tunnel
EES41_RS21735	COG0089	rRNA binding
EES41_RS21740	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EES41_RS21745	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EES41_RS21750	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EES41_RS21755	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EES41_RS21760	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EES41_RS21765	COG0255	Belongs to the universal ribosomal protein uL29 family
EES41_RS21770	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EES41_RS21775	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EES41_RS21780	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EES41_RS21785	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EES41_RS21790	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EES41_RS21800	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EES41_RS21805	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EES41_RS21810	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EES41_RS21815	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EES41_RS21820	COG1841	ribosomal large subunit assembly
EES41_RS21825	COG0200	Binds to the 23S rRNA
EES41_RS21830	COG0201	protein transport
EES41_RS21835	COG0563	adenylate kinase activity
EES41_RS21845	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EES41_RS21850	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EES41_RS21855	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EES41_RS21860	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EES41_RS21865	COG0202	RNA polymerase activity
EES41_RS21870	COG0203	ribosomal protein L17
EES41_RS21875	COG0101	tRNA pseudouridine synthase activity
EES41_RS21880	COG0488	(ABC) transporter
EES41_RS21890	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EES41_RS21895	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EES41_RS21900	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EES41_RS21910	COG1072	(Pantothenic acid kinase))
EES41_RS21915	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EES41_RS21920	COG0736	holo-[acyl-carrier-protein] synthase activity
EES41_RS21930	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EES41_RS21940	COG0802	atpase or kinase
EES41_RS21965	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EES41_RS21985	COG0726	polysaccharide deacetylase
EES41_RS21990	COG0726	polysaccharide deacetylase
EES41_RS22000	COG1316	TRANSCRIPTIONal
EES41_RS22005	COG2205	protein histidine kinase activity
EES41_RS22010	COG0745	RESPONSE REGULATOR receiver
EES41_RS22015	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EES41_RS22030	COG4221	oxidoreductase activity
EES41_RS22035	COG0583	DNA-binding transcription factor activity
EES41_RS22045	COG2197	response regulator
EES41_RS22050	COG1595	DNA-templated transcription, initiation
EES41_RS22060	COG0516	GMP reductase activity
EES41_RS22065	COG2337	Toxic component of a toxin-antitoxin (TA) module
EES41_RS22085	COG2815	serine threonine protein kinase
EES41_RS22085	COG0515	serine threonine protein kinase
EES41_RS22095	COG0515	serine threonine protein kinase
EES41_RS22100	COG1012	belongs to the aldehyde dehydrogenase family
EES41_RS22120	COG0519	Catalyzes the synthesis of GMP from XMP
EES41_RS22120	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EES41_RS22155	COG2197	response regulator
EES41_RS22165	COG0791	NLP P60 protein
EES41_RS22175	COG0640	Transcriptional regulator
EES41_RS22190	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
EES41_RS22195	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EES41_RS22195	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EES41_RS22210	COG0714	Associated with various cellular activities
EES41_RS22220	COG3552	Protein containing von Willebrand factor type A (VWA) domain
EES41_RS22225	COG0045	succinate-CoA ligase (ADP-forming) activity
EES41_RS22260	COG0138	bifunctional purine biosynthesis protein purh
EES41_RS22270	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EES41_RS22280	COG0039	L-malate dehydrogenase activity
EES41_RS22300	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EES41_RS22305	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EES41_RS22320	COG0754	glutathionylspermidine amidase activity
EES41_RS22325	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EES41_RS22330	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EES41_RS22335	COG0180	Tryptophanyl-tRNA synthetase
EES41_RS22365	COG1408	metallophosphoesterase
EES41_RS22370	COG1309	transcriptional regulator
EES41_RS22385	COG0596	Alpha beta hydrolase
EES41_RS22400	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EES41_RS22405	COG1053	succinate dehydrogenase
EES41_RS22415	COG2009	succinate dehydrogenase
EES41_RS22425	COG1595	DNA-templated transcription, initiation
EES41_RS22440	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EES41_RS22440	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EES41_RS22450	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EES41_RS22460	COG1216	Glycosyl transferase, family 2
EES41_RS22470	COG2089	acid synthase
EES41_RS22480	COG1473	amidohydrolase
EES41_RS22480	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
EES41_RS22485	COG1744	ABC transporter substrate-binding protein PnrA-like
EES41_RS22490	COG3845	ABC transporter
EES41_RS22495	COG4603	Belongs to the binding-protein-dependent transport system permease family
EES41_RS22500	COG1079	Belongs to the binding-protein-dependent transport system permease family
EES41_RS22525	COG2814	Major facilitator Superfamily
EES41_RS22530	COG0583	DNA-binding transcription factor activity
EES41_RS22555	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EES41_RS22600	COG1012	belongs to the aldehyde dehydrogenase family
EES41_RS22605	COG1012	belongs to the aldehyde dehydrogenase family
EES41_RS22620	COG1846	Transcriptional regulator
EES41_RS22630	COG1595	DNA-templated transcription, initiation
EES41_RS22635	COG0745	RESPONSE REGULATOR receiver
EES41_RS22640	COG2205	protein histidine kinase activity
EES41_RS22650	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EES41_RS22670	COG1349	DNA-binding transcription factor activity
EES41_RS22675	COG4770	biotin carboxylase activity
EES41_RS22685	COG0424	maF-like protein
EES41_RS22695	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EES41_RS22705	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
EES41_RS22710	COG1024	Enoyl-CoA hydratase
EES41_RS22720	COG2986	histidine ammonia-lyase
EES41_RS22735	COG1376	ErfK ybiS ycfS ynhG family protein
EES41_RS22750	COG1064	alcohol dehydrogenase
EES41_RS22755	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EES41_RS22790	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EES41_RS22805	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EES41_RS22820	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EES41_RS22835	COG1331	Highly conserved protein containing a thioredoxin domain
EES41_RS22845	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
EES41_RS22860	COG0436	Aminotransferase
EES41_RS22895	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
EES41_RS22905	COG1414	Transcriptional regulator
EES41_RS22935	COG2894	cell division
EES41_RS22965	COG4585	Histidine kinase
EES41_RS22990	COG2885	chlorophyll binding
EES41_RS22995	COG1595	DNA-templated transcription, initiation
EES41_RS23000	COG1252	NADH dehydrogenase
EES41_RS23025	COG0726	polysaccharide deacetylase
EES41_RS23060	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EES41_RS23065	COG0667	Aldo Keto reductase
EES41_RS23070	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EES41_RS23075	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EES41_RS23095	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EES41_RS23100	COG0450	alkyl hydroperoxide reductase
EES41_RS23105	COG0181	hydroxymethylbilane synthase activity
EES41_RS23110	COG0181	hydroxymethylbilane synthase activity
EES41_RS23115	COG0113	porphobilinogen synthase activity
EES41_RS23210	COG1388	LysM domain
EES41_RS23210	COG3942	CHAP domain
EES41_RS23410	COG1136	(ABC) transporter
EES41_RS23430	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EES41_RS23450	COG0114	fumarate hydratase activity
EES41_RS23465	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EES41_RS23465	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EES41_RS23490	COG0778	Nitroreductase
EES41_RS23495	COG1722	exodeoxyribonuclease VII activity
EES41_RS23500	COG1570	exodeoxyribonuclease VII activity
EES41_RS23505	COG1113	amino acid transport
EES41_RS23510	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EES41_RS23515	COG1940	carbohydrate kinase activity
EES41_RS23525	COG0012	GTP binding
EES41_RS23595	COG1842	Phage shock protein A
EES41_RS23635	COG1217	gtp-binding protein TYPA
EES41_RS23640	COG0747	negative chemotaxis
EES41_RS23650	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EES41_RS23660	COG4608	Belongs to the ABC transporter superfamily
EES41_RS23675	COG1132	(ABC) transporter
EES41_RS23695	COG4166	transmembrane transport
EES41_RS23700	COG0601	transmembrane transport
EES41_RS23705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EES41_RS23715	COG4608	Belongs to the ABC transporter superfamily
EES41_RS23730	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EES41_RS23745	COG1131	(ABC) transporter
EES41_RS23755	COG4585	Histidine kinase
EES41_RS23760	COG2197	response regulator
EES41_RS23795	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EES41_RS23800	COG1611	Belongs to the LOG family
EES41_RS23815	COG0519	Catalyzes the synthesis of GMP from XMP
EES41_RS23820	COG1024	Enoyl-CoA hydratase
EES41_RS23835	COG1595	DNA-templated transcription, initiation
EES41_RS23845	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EES41_RS23850	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EES41_RS23885	COG0598	Magnesium transport protein CorA
EES41_RS23905	COG2095	MarC family integral membrane protein
EES41_RS23910	COG2267	carboxylic ester hydrolase activity
EES41_RS23965	COG0601	transmembrane transport
EES41_RS24005	COG3209	COG3209 Rhs family protein
EES41_RS24030	COG0210	DNA helicase
EES41_RS24035	COG0210	DNA helicase
EES41_RS24040	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EES41_RS24080	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EES41_RS24140	COG3480	Lon protease (S16) C-terminal proteolytic domain
EES41_RS24150	COG1615	UPF0182 protein
EES41_RS24175	COG0753	catalase activity
EES41_RS24185	COG0483	inositol monophosphate 1-phosphatase activity
EES41_RS24195	COG2076	Multidrug Resistance protein
EES41_RS24200	COG1162	GTPase activity
EES41_RS24205	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EES41_RS24215	COG2135	peptidase activity
EES41_RS24225	COG1595	DNA-templated transcription, initiation
EES41_RS24230	COG5662	AntiSigma factor
EES41_RS24250	COG0242	peptide deformylase activity
EES41_RS24290	COG1966	Carbon starvation protein
EES41_RS24295	COG2188	Transcriptional regulator
EES41_RS24300	COG2182	Extracellular solute-binding protein
EES41_RS24305	COG1175	transmembrane transport
EES41_RS24310	COG0395	ABC-type sugar transport system, permease component
EES41_RS24315	COG1472	Belongs to the glycosyl hydrolase 3 family
EES41_RS24320	COG0363	glucosamine-6-phosphate deaminase activity
EES41_RS24325	COG1028	Short-chain dehydrogenase reductase Sdr
EES41_RS24330	COG1309	transcriptional regulator
EES41_RS24345	COG1597	lipid kinase activity
EES41_RS24375	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EES41_RS24385	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EES41_RS24385	COG1017	nitric oxide dioxygenase activity
EES41_RS24390	COG1959	2 iron, 2 sulfur cluster binding
EES41_RS24395	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EES41_RS24400	COG0142	geranyltranstransferase activity
EES41_RS24420	COG5640	endopeptidase activity
EES41_RS24450	COG0604	alcohol dehydrogenase
EES41_RS24465	COG0765	amino acid transport
EES41_RS24470	COG1126	abc transporter atp-binding protein
EES41_RS24540	COG0508	dehydrogenase complex catalyzes the overall conversion of
EES41_RS24540	COG0567	Dehydrogenase, E1 component
EES41_RS24545	COG2205	protein histidine kinase activity
EES41_RS24550	COG0745	RESPONSE REGULATOR receiver
EES41_RS24565	COG1131	(ABC) transporter
EES41_RS24605	COG2897	thiosulfate sulfurtransferase activity
EES41_RS24620	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EES41_RS24665	COG3883	PFAM NLP P60 protein
EES41_RS24665	COG0791	NLP P60 protein
EES41_RS24680	COG0772	Belongs to the SEDS family
EES41_RS24710	COG2205	protein histidine kinase activity
EES41_RS24730	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EES41_RS24735	COG3285	dna ligase
EES41_RS24735	COG1793	dna ligase
EES41_RS24740	COG1793	dna ligase
EES41_RS24805	COG0019	diaminopimelate decarboxylase activity
EES41_RS24810	COG0460	homoserine dehydrogenase
EES41_RS24815	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EES41_RS24820	COG0083	homoserine kinase activity
EES41_RS24830	COG1316	TRANSCRIPTIONal
EES41_RS24835	COG0254	rRNA binding
EES41_RS24840	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EES41_RS24845	COG2890	protein-(glutamine-N5) methyltransferase activity
EES41_RS24855	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EES41_RS24860	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EES41_RS24880	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EES41_RS24885	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EES41_RS24890	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EES41_RS24895	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EES41_RS24900	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EES41_RS24905	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EES41_RS24910	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EES41_RS24925	COG2197	response regulator
EES41_RS24930	COG4585	Histidine kinase
EES41_RS24950	COG1250	3-hydroxyacyl-CoA dehydrogenase
EES41_RS24965	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
EES41_RS25000	COG1131	(ABC) transporter
EES41_RS25020	COG0183	Belongs to the thiolase family
EES41_RS25090	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EES41_RS25090	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EES41_RS25095	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EES41_RS25105	COG0189	ligase activity
EES41_RS25110	COG1181	Belongs to the D-alanine--D-alanine ligase family
EES41_RS25115	COG2814	Major facilitator Superfamily
EES41_RS25120	COG1181	Belongs to the D-alanine--D-alanine ligase family
EES41_RS25125	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EES41_RS25130	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EES41_RS25190	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EES41_RS25195	COG0280	phosphate acetyltransferase
EES41_RS25195	COG0857	belongs to the CobB CobQ family
EES41_RS25200	COG0205	6-phosphofructokinase activity
EES41_RS25230	COG0366	Alpha amylase catalytic
EES41_RS25235	COG0366	Alpha amylase catalytic
EES41_RS25240	COG0058	SHG alpha-glucan phosphorylase activity
EES41_RS25265	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EES41_RS25270	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EES41_RS25275	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
EES41_RS25315	COG0489	protein tyrosine kinase activity
EES41_RS25320	COG0297	glycogen (starch) synthase activity
EES41_RS25340	COG1846	Transcriptional regulator
EES41_RS25395	COG1122	ATPase activity
EES41_RS25405	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
EES41_RS25410	COG0310	cobalt ion transport
EES41_RS25425	COG1760	l-serine dehydratase
EES41_RS25430	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EES41_RS25435	COG0509	glycine decarboxylation via glycine cleavage system
EES41_RS25440	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EES41_RS25460	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EES41_RS25465	COG0747	negative chemotaxis
EES41_RS25475	COG0444	Belongs to the ABC transporter superfamily
EES41_RS25480	COG4608	Belongs to the ABC transporter superfamily
EES41_RS25485	COG2860	membrane
EES41_RS25510	COG0482	sulfurtransferase activity
EES41_RS25515	COG1028	Short-chain dehydrogenase reductase Sdr
EES41_RS25515	COG3321	synthase
EES41_RS25515	COG0604	alcohol dehydrogenase
EES41_RS25525	COG1404	Belongs to the peptidase S8 family
EES41_RS25540	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EES41_RS25550	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EES41_RS25555	COG0154	amidase activity
EES41_RS25565	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EES41_RS25580	COG2375	cellular response to nickel ion
EES41_RS25580	COG1132	(ABC) transporter
EES41_RS25585	COG2318	DinB family
EES41_RS25600	COG2409	Drug exporters of the RND superfamily
EES41_RS25605	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EES41_RS25615	COG2197	response regulator
EES41_RS25625	COG2133	pyrroloquinoline quinone binding
EES41_RS25630	COG0667	Aldo Keto reductase
EES41_RS25640	COG3300	MHYT domain
EES41_RS25640	COG5001	Diguanylate cyclase
EES41_RS25650	COG0440	acetolactate synthase activity
EES41_RS25655	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EES41_RS25660	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EES41_RS25665	COG0477	Major facilitator Superfamily
EES41_RS25680	COG3835	regulator
EES41_RS25685	COG0506	proline dehydrogenase activity
EES41_RS25690	COG1012	belongs to the aldehyde dehydrogenase family
EES41_RS25695	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
EES41_RS25695	COG0778	Nitroreductase
EES41_RS25710	COG3511	phospholipase C
EES41_RS25715	COG2130	NADP-dependent
EES41_RS25720	COG0583	DNA-binding transcription factor activity
EES41_RS25725	COG0473	3-isopropylmalate dehydrogenase activity
EES41_RS25730	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EES41_RS25745	COG0832	Belongs to the urease beta subunit family
EES41_RS25745	COG0831	urea catabolic process
EES41_RS25750	COG0804	urea catabolic process
EES41_RS25755	COG2957	Belongs to the agmatine deiminase family
EES41_RS25760	COG1309	transcriptional regulator
EES41_RS25765	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EES41_RS25780	COG2353	YceI-like domain
EES41_RS25785	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EES41_RS25805	COG2018	Roadblock/LC7 domain
EES41_RS25825	COG2018	Roadblock/LC7 domain
EES41_RS25830	COG5002	protein histidine kinase activity
EES41_RS25840	COG0179	Fumarylacetoacetate (FAA) hydrolase
EES41_RS25845	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EES41_RS25855	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
EES41_RS25890	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EES41_RS25895	COG0066	3-isopropylmalate dehydratase activity
EES41_RS25905	COG0776	regulation of translation
EES41_RS25910	COG1920	GTP binding
EES41_RS25920	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EES41_RS25925	COG1181	Belongs to the D-alanine--D-alanine ligase family
EES41_RS25945	COG0351	phosphomethylpyrimidine kinase
EES41_RS25950	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EES41_RS25955	COG1461	Dihydroxyacetone kinase
EES41_RS25960	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EES41_RS25965	COG0742	ribosomal rna small subunit methyltransferase
EES41_RS25970	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EES41_RS25985	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EES41_RS25990	COG0571	ribonuclease III activity
EES41_RS25995	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EES41_RS26000	COG1733	regulation of RNA biosynthetic process
EES41_RS26005	COG2340	Cysteine-rich secretory protein family
EES41_RS26010	COG1254	Belongs to the acylphosphatase family
EES41_RS26020	COG1196	nuclear chromosome segregation
EES41_RS26025	COG0477	Major facilitator Superfamily
EES41_RS26065	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
EES41_RS26075	COG3457	Alanine racemase
EES41_RS26080	COG0626	cystathionine gamma-synthase activity
EES41_RS26085	COG1735	metal-dependent hydrolase with the TIM-barrel fold
EES41_RS26105	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EES41_RS26115	COG0442	prolyl-tRNA aminoacylation
EES41_RS26125	COG0228	four-way junction DNA binding
EES41_RS26130	COG1837	Belongs to the UPF0109 family
EES41_RS26135	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EES41_RS26140	COG0336	Belongs to the RNA methyltransferase TrmD family
EES41_RS26145	COG0335	large ribosomal subunit rRNA binding
EES41_RS26160	COG0681	Belongs to the peptidase S26 family
EES41_RS26185	COG0792	nuclease activity
EES41_RS26200	COG1191	sigma factor activity
EES41_RS26215	COG0052	Belongs to the universal ribosomal protein uS2 family
EES41_RS26220	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EES41_RS26225	COG0528	UMP kinase activity
EES41_RS26230	COG0233	cytoplasmic translational termination
EES41_RS26240	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EES41_RS26255	COG3842	ATPase activity
EES41_RS26275	COG1136	(ABC) transporter
EES41_RS26280	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EES41_RS26290	COG1012	belongs to the aldehyde dehydrogenase family
EES41_RS26310	COG2197	response regulator
EES41_RS26315	COG4585	Histidine kinase
EES41_RS26325	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EES41_RS26345	COG1012	belongs to the aldehyde dehydrogenase family
EES41_RS26350	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EES41_RS26355	COG3842	ATPase activity
EES41_RS26360	COG1176	ABC-type spermidine putrescine transport system, permease component I
EES41_RS26365	COG1177	transmembrane transport
EES41_RS26370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EES41_RS26395	COG2508	Transcriptional regulator
EES41_RS26415	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EES41_RS26420	COG0750	zinc metalloprotease
EES41_RS26425	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EES41_RS26440	COG0442	prolyl-tRNA aminoacylation
EES41_RS26445	COG0330	HflC and HflK could
EES41_RS26465	COG0779	Required for maturation of 30S ribosomal subunits
EES41_RS26480	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EES41_RS26490	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EES41_RS26495	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EES41_RS26505	COG0455	bacterial-type flagellum organization
EES41_RS26525	COG1404	Belongs to the peptidase S8 family
EES41_RS26550	COG1674	ftsk spoiiie
EES41_RS26560	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EES41_RS26565	COG1185	polyribonucleotide nucleotidyltransferase activity
EES41_RS26570	COG0612	Peptidase, M16
EES41_RS26575	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EES41_RS26595	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
EES41_RS26600	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EES41_RS26605	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EES41_RS26630	COG2318	DinB family
EES41_RS26640	COG4999	Histidine kinase
EES41_RS26640	COG2205	protein histidine kinase activity
EES41_RS26640	COG3850	Histidine kinase
EES41_RS26640	COG3437	response regulator, receiver
EES41_RS26650	COG1674	ftsk spoiiie
EES41_RS26660	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EES41_RS26670	COG1546	Belongs to the CinA family
EES41_RS26670	COG1058	Belongs to the CinA family
EES41_RS26675	COG1396	sequence-specific DNA binding
EES41_RS26685	COG1028	Short-chain dehydrogenase reductase Sdr
EES41_RS26690	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EES41_RS26700	COG1201	RNA secondary structure unwinding
EES41_RS26705	COG2207	Transcriptional regulator
EES41_RS26705	COG1917	Cupin 2, conserved barrel domain protein
EES41_RS26745	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EES41_RS26755	COG2897	thiosulfate sulfurtransferase activity
EES41_RS26770	COG0765	amino acid transport
EES41_RS26775	COG0765	amino acid transport
EES41_RS26780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EES41_RS26785	COG1126	abc transporter atp-binding protein
EES41_RS26790	COG0745	RESPONSE REGULATOR receiver
EES41_RS26795	COG2205	protein histidine kinase activity
EES41_RS26810	COG1609	Transcriptional regulator
EES41_RS26825	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EES41_RS26845	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EES41_RS26855	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EES41_RS26860	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EES41_RS26870	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EES41_RS26905	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EES41_RS26910	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EES41_RS26915	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EES41_RS26935	COG0588	phosphoglycerate mutase activity
EES41_RS26960	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EES41_RS26995	COG1136	(ABC) transporter
EES41_RS27005	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EES41_RS27030	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EES41_RS27035	COG4565	transcriptional regulatory protein
EES41_RS27040	COG3290	protein histidine kinase activity
EES41_RS27065	COG0372	Belongs to the citrate synthase family
EES41_RS27080	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EES41_RS27085	COG0612	Peptidase, M16
EES41_RS27100	COG1802	Transcriptional regulator
EES41_RS27105	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EES41_RS27125	COG1435	thymidine kinase activity
EES41_RS27160	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EES41_RS27170	COG0745	RESPONSE REGULATOR receiver
EES41_RS27175	COG2205	protein histidine kinase activity
EES41_RS27200	COG0756	dUTP diphosphatase activity
EES41_RS27235	COG0569	domain protein
EES41_RS27240	COG0531	amino acid
EES41_RS27245	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EES41_RS27275	COG0252	asparaginase activity
EES41_RS27305	COG0431	NADPH-dependent FMN reductase
EES41_RS27320	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EES41_RS27325	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EES41_RS27340	COG1799	cell septum assembly
EES41_RS27365	COG2040	homocysteine
EES41_RS27370	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EES41_RS27380	COG2235	arginine
EES41_RS27385	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EES41_RS27395	COG1024	Enoyl-CoA hydratase
EES41_RS27415	COG1960	acyl-CoA dehydrogenase activity
EES41_RS27430	COG0006	proline dipeptidase activity
EES41_RS27460	COG3938	Belongs to the proline racemase family
EES41_RS27490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EES41_RS27495	COG0601	transmembrane transport
EES41_RS27505	COG4608	Belongs to the ABC transporter superfamily
EES41_RS27530	COG0494	nUDIX hydrolase
EES41_RS27550	COG0457	Tetratricopeptide repeat
EES41_RS27560	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EES41_RS27565	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EES41_RS27570	COG1609	Transcriptional regulator
EES41_RS27580	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EES41_RS27585	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EES41_RS27590	COG1653	transport
EES41_RS27595	COG1175	transmembrane transport
EES41_RS27600	COG0395	ABC-type sugar transport system, permease component
EES41_RS27610	COG1940	carbohydrate kinase activity
EES41_RS27615	COG4213	ABC transporter substrate-binding protein
EES41_RS27625	COG1172	Belongs to the binding-protein-dependent transport system permease family
EES41_RS27630	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EES41_RS27635	COG0531	amino acid
EES41_RS27640	COG1316	TRANSCRIPTIONal
EES41_RS27650	COG1024	Enoyl-CoA hydratase
EES41_RS27650	COG1250	3-hydroxyacyl-CoA dehydrogenase
EES41_RS27655	COG0183	Belongs to the thiolase family
EES41_RS27680	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EES41_RS27700	COG0446	pyridine nucleotide-disulphide oxidoreductase
EES41_RS27710	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EES41_RS27715	COG3253	May function as heme-dependent peroxidase
EES41_RS27720	COG0596	Alpha beta hydrolase
EES41_RS27730	COG3220	belongs to the UPF0276 family
EES41_RS27745	COG1116	anion transmembrane transporter activity
EES41_RS27765	COG2326	polyphosphate kinase activity
EES41_RS27795	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EES41_RS27800	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EES41_RS27815	COG3511	phospholipase C
EES41_RS27820	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
EES41_RS27825	COG1396	sequence-specific DNA binding
EES41_RS27835	COG0504	CTP synthase activity
EES41_RS27910	COG0515	serine threonine protein kinase
EES41_RS27945	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EES41_RS27955	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EES41_RS27960	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EES41_RS27985	COG0529	Catalyzes the synthesis of activated sulfate
EES41_RS27990	COG0175	sulfate reduction
EES41_RS28010	COG0456	acetyltransferase
EES41_RS28010	COG1846	Transcriptional regulator
EES41_RS28020	COG1960	acyl-CoA dehydrogenase activity
EES41_RS28030	COG1162	GTPase activity
EES41_RS28055	COG0028	Belongs to the TPP enzyme family
EES41_RS28075	COG1802	Transcriptional regulator
EES41_RS28100	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EES41_RS28105	COG2252	PERMEase
EES41_RS28155	COG4552	Acetyltransferase involved in intracellular survival and related
EES41_RS28225	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EES41_RS28250	COG2304	oxidoreductase activity
EES41_RS28270	COG0596	Alpha beta hydrolase
EES41_RS28275	COG0475	glutathione-regulated potassium exporter activity
EES41_RS28285	COG2255	four-way junction helicase activity
EES41_RS28315	COG0598	Magnesium transport protein CorA
EES41_RS28325	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EES41_RS28330	COG0386	Belongs to the glutathione peroxidase family
EES41_RS28340	COG3960	tartronate-semialdehyde synthase activity
EES41_RS28365	COG2197	response regulator
EES41_RS28370	COG4585	Histidine kinase
EES41_RS28380	COG0753	catalase activity
EES41_RS28385	COG2084	Dehydrogenase
EES41_RS28390	COG3622	Belongs to the hyi family
EES41_RS28410	COG2351	hydroxyisourate hydrolase activity
EES41_RS28425	COG2233	PERMEase
EES41_RS28445	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EES41_RS28465	COG2197	response regulator
EES41_RS28470	COG4585	Histidine kinase
EES41_RS28480	COG1136	(ABC) transporter
EES41_RS28485	COG1414	Transcriptional regulator
EES41_RS28490	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EES41_RS28495	COG4266	Belongs to the allantoicase family
EES41_RS28500	COG1028	Short-chain dehydrogenase reductase Sdr
EES41_RS28520	COG0673	inositol 2-dehydrogenase activity
EES41_RS28535	COG1129	ABC transporter
EES41_RS28565	COG1126	abc transporter atp-binding protein
EES41_RS28570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EES41_RS28575	COG0765	amino acid transport
EES41_RS28580	COG0765	amino acid transport
EES41_RS28590	COG1376	ErfK ybiS ycfS ynhG family protein
EES41_RS28605	COG0745	RESPONSE REGULATOR receiver
EES41_RS28610	COG2205	protein histidine kinase activity
EES41_RS28630	COG0405	Gamma-glutamyltransferase
EES41_RS28660	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EES41_RS28665	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EES41_RS28680	COG4104	PAAR repeat-containing protein
EES41_RS28680	COG3209	COG3209 Rhs family protein
EES41_RS28690	COG0483	inositol monophosphate 1-phosphatase activity
EES41_RS28705	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EES41_RS28725	COG1335	isochorismatase
EES41_RS28735	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EES41_RS28750	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EES41_RS28755	COG1929	Belongs to the glycerate kinase type-1 family
EES41_RS28765	COG0688	phosphatidylethanolamine metabolic process
EES41_RS28770	COG1960	acyl-CoA dehydrogenase activity
EES41_RS28785	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EES41_RS28785	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EES41_RS28790	COG0604	alcohol dehydrogenase
EES41_RS28800	COG1250	3-hydroxyacyl-CoA dehydrogenase
EES41_RS28825	COG2362	D-Aminopeptidase
EES41_RS28830	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EES41_RS28855	COG2226	methyltransferase
EES41_RS28890	COG0531	amino acid
EES41_RS28900	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EES41_RS28910	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EES41_RS28925	COG2154	pterin-4-alpha-carbinolamine dehydratase
EES41_RS28965	COG1022	Amp-dependent synthetase and ligase
EES41_RS28985	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EES41_RS28990	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EES41_RS29040	COG2815	serine threonine protein kinase
EES41_RS29040	COG0515	serine threonine protein kinase
EES41_RS29060	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EES41_RS29065	COG1288	antiporter activity
EES41_RS29110	COG1486	melibiose metabolic process
EES41_RS29120	COG0494	nUDIX hydrolase
EES41_RS29140	COG1793	dna ligase
EES41_RS29185	COG0488	(ABC) transporter
EES41_RS29215	COG1515	deoxyribonuclease V activity
EES41_RS29220	COG3268	Saccharopine dehydrogenase
EES41_RS29230	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EES41_RS29235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EES41_RS29240	COG1960	acyl-CoA dehydrogenase activity
EES41_RS29245	COG0183	Belongs to the thiolase family
EES41_RS29250	COG1024	Enoyl-CoA hydratase
EES41_RS29250	COG1250	3-hydroxyacyl-CoA dehydrogenase
EES41_RS29260	COG0789	Transcriptional regulator
EES41_RS29265	COG1022	Amp-dependent synthetase and ligase
EES41_RS29300	COG1012	belongs to the aldehyde dehydrogenase family
EES41_RS29325	COG0300	oxidoreductase activity
EES41_RS29335	COG4977	sequence-specific DNA binding
EES41_RS29345	COG1024	Enoyl-CoA hydratase
EES41_RS29355	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EES41_RS29360	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EES41_RS29375	COG0371	Dehydrogenase
EES41_RS29395	COG1134	teichoic acid transport
EES41_RS29410	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EES41_RS29420	COG1657	PFAM Prenyltransferase squalene oxidase
EES41_RS29440	COG2365	Tyrosine phosphatase family
EES41_RS29450	COG2755	lipolytic protein G-D-S-L family
EES41_RS29495	COG3958	Transketolase
EES41_RS29500	COG3959	Transketolase, thiamine diphosphate binding domain
EES41_RS29520	COG0583	DNA-binding transcription factor activity
EES41_RS29530	COG1335	isochorismatase
EES41_RS29555	COG0747	negative chemotaxis
EES41_RS29560	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EES41_RS29575	COG2318	DinB family
EES41_RS29585	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EES41_RS29600	COG1968	undecaprenyl-diphosphatase activity
EES41_RS29615	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EES41_RS29665	COG0110	maltose O-acetyltransferase activity
EES41_RS29680	COG1832	CoA-binding protein
EES41_RS29685	COG1739	Uncharacterized protein family UPF0029
EES41_RS29700	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EES41_RS29710	COG1396	sequence-specific DNA binding
EES41_RS29710	COG3800	Transcriptional regulator
EES41_RS29720	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EES41_RS29735	COG2274	protein secretion by the type I secretion system
EES41_RS29750	COG0420	3'-5' exonuclease activity
EES41_RS29755	COG0419	ATPase involved in DNA repair
EES41_RS29760	COG1522	sequence-specific DNA binding
EES41_RS29785	COG2267	carboxylic ester hydrolase activity
EES41_RS29790	COG2188	Transcriptional regulator
EES41_RS29800	COG2197	response regulator
EES41_RS29805	COG4585	Histidine kinase
EES41_RS29830	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EES41_RS29850	COG2226	methyltransferase
EES41_RS29855	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EES41_RS29860	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EES41_RS29865	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EES41_RS29890	COG0831	urea catabolic process
EES41_RS29895	COG0832	Belongs to the urease beta subunit family
EES41_RS29900	COG0804	urea catabolic process
EES41_RS29905	COG0830	nickel cation binding
EES41_RS29910	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
EES41_RS29915	COG0829	nickel cation binding
EES41_RS29935	COG0205	6-phosphofructokinase activity
EES41_RS29940	COG3442	glutamine amidotransferase
EES41_RS29950	COG0242	peptide deformylase activity
EES41_RS29960	COG1960	acyl-CoA dehydrogenase activity
EES41_RS30055	COG0243	molybdopterin cofactor binding
EES41_RS30085	COG0514	ATP-dependent DNA helicase (RecQ)
EES41_RS30090	COG1012	belongs to the aldehyde dehydrogenase family
EES41_RS30100	COG4175	Glycine betaine
EES41_RS30100	COG0517	IMP dehydrogenase activity
EES41_RS30105	COG4176	ABC-type proline glycine betaine transport system permease component
EES41_RS30115	COG0515	serine threonine protein kinase
EES41_RS30140	COG1505	serine-type exopeptidase activity
EES41_RS30190	COG1404	Belongs to the peptidase S8 family
EES41_RS30355	COG1012	belongs to the aldehyde dehydrogenase family
EES41_RS30425	COG2018	Roadblock/LC7 domain
EES41_RS30435	COG3012	SEC-C Motif Domain Protein
EES41_RS30440	COG1946	Acyl-CoA thioesterase
EES41_RS30455	COG1132	(ABC) transporter
EES41_RS30460	COG1132	(ABC) transporter
EES41_RS30475	COG1132	(ABC) transporter
EES41_RS30485	COG2072	flavoprotein involved in K transport
EES41_RS30490	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EES41_RS30500	COG0702	epimerase
EES41_RS30530	COG0588	phosphoglycerate mutase activity
EES41_RS30590	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EES41_RS30605	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EES41_RS30635	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EES41_RS30650	COG1335	isochorismatase
EES41_RS30660	COG0783	Belongs to the Dps family
EES41_RS30665	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EES41_RS30670	COG2267	carboxylic ester hydrolase activity
EES41_RS30680	COG1228	amidohydrolase
EES41_RS30700	COG0438	transferase activity, transferring glycosyl groups
EES41_RS30710	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EES41_RS30715	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EES41_RS30790	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EES41_RS30805	COG1250	3-hydroxyacyl-CoA dehydrogenase
EES41_RS30825	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EES41_RS30830	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EES41_RS30835	COG2192	nodulation
EES41_RS30840	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EES41_RS30865	COG1132	(ABC) transporter
EES41_RS30870	COG1132	(ABC) transporter
EES41_RS30890	COG2124	cytochrome p450
EES41_RS30945	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EES41_RS30965	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EES41_RS31010	COG4762	Protein conserved in bacteria
EES41_RS31030	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EES41_RS31060	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EES41_RS31060	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EES41_RS31065	COG0726	polysaccharide deacetylase
EES41_RS31110	COG1309	transcriptional regulator
EES41_RS31125	COG1309	transcriptional regulator
EES41_RS31130	COG0583	DNA-binding transcription factor activity
EES41_RS31140	COG1053	succinate dehydrogenase
EES41_RS31145	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EES41_RS31160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EES41_RS31170	COG3360	Dodecin
EES41_RS31175	COG2182	Extracellular solute-binding protein
EES41_RS31190	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
EES41_RS31195	COG0121	glutamine amidotransferase
EES41_RS31200	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EES41_RS31205	COG3572	ergothioneine biosynthetic process
EES41_RS31230	COG1609	Transcriptional regulator
EES41_RS31235	COG0183	Belongs to the thiolase family
EES41_RS31245	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EES41_RS31300	COG2813	Specifically methylates the guanine in position
EES41_RS31315	COG0277	FAD linked oxidase domain protein
EES41_RS31375	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EES41_RS31385	COG0254	rRNA binding
EES41_RS31395	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EES41_RS31400	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EES41_RS31420	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EES41_RS31455	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EES41_RS31460	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EES41_RS31470	COG0531	amino acid
EES41_RS31485	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EES41_RS31490	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EES41_RS31495	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EES41_RS31530	COG4221	oxidoreductase activity
EES41_RS31550	COG0156	8-amino-7-oxononanoate synthase activity
EES41_RS31560	COG1428	Deoxynucleoside kinase
EES41_RS31585	COG1132	(ABC) transporter
EES41_RS31590	COG1132	(ABC) transporter
EES41_RS31600	COG0515	serine threonine protein kinase
EES41_RS31610	COG0477	Major facilitator Superfamily
EES41_RS31635	COG0783	Belongs to the Dps family
EES41_RS31640	COG1028	Short-chain dehydrogenase reductase Sdr
EES41_RS31665	COG0745	RESPONSE REGULATOR receiver
EES41_RS31670	COG2205	protein histidine kinase activity
EES41_RS31685	COG2197	response regulator
EES41_RS31730	COG0477	Major facilitator Superfamily
EES41_RS31745	COG2957	Belongs to the agmatine deiminase family
EES41_RS31750	COG1309	transcriptional regulator
EES41_RS31755	COG2957	Belongs to the agmatine deiminase family
EES41_RS31765	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EES41_RS31795	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EES41_RS31805	COG3290	protein histidine kinase activity
EES41_RS31880	COG0393	Putative heavy-metal-binding
EES41_RS31935	COG3547	Transposase (IS116 IS110 IS902 family)
EES41_RS31950	COG2814	Major facilitator Superfamily
EES41_RS31965	COG2356	endonuclease I
EES41_RS31980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EES41_RS32005	COG3864	Putative metallopeptidase domain
EES41_RS32040	COG0515	serine threonine protein kinase
EES41_RS32040	COG2815	serine threonine protein kinase
EES41_RS32045	COG4585	Histidine kinase
EES41_RS32050	COG2197	response regulator
EES41_RS32095	COG1024	Enoyl-CoA hydratase
EES41_RS32115	COG1960	acyl-CoA dehydrogenase activity
EES41_RS32120	COG1960	acyl-CoA dehydrogenase activity
EES41_RS32130	COG2304	oxidoreductase activity
EES41_RS32150	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
EES41_RS32155	COG3511	phospholipase C
EES41_RS32190	COG1301	dicarboxylic acid transport
EES41_RS32195	COG3290	protein histidine kinase activity
EES41_RS32200	COG4565	transcriptional regulatory protein
EES41_RS32215	COG0076	glutamate decarboxylase activity
EES41_RS32235	COG1414	Transcriptional regulator
EES41_RS32250	COG0667	Aldo Keto reductase
EES41_RS32295	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EES41_RS32300	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EES41_RS32310	COG3547	Transposase (IS116 IS110 IS902 family)
EES41_RS32320	COG0667	Aldo Keto reductase
EES41_RS32325	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EES41_RS32335	COG1131	(ABC) transporter
EES41_RS32340	COG1793	dna ligase
EES41_RS32360	COG0477	Major facilitator Superfamily
EES41_RS32365	COG1404	Belongs to the peptidase S8 family
EES41_RS32365	COG4412	M6 family metalloprotease domain protein
EES41_RS32365	COG4412	M6 family metalloprotease domain protein
EES41_RS32365	COG1404	Belongs to the peptidase S8 family
EES41_RS32385	COG2124	cytochrome p450
EES41_RS32410	COG3265	gluconokinase activity
EES41_RS32420	COG4977	sequence-specific DNA binding
EES41_RS32425	COG0346	lactoylglutathione lyase activity
EES41_RS32430	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EES41_RS32480	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EES41_RS32485	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EES41_RS32495	COG1132	(ABC) transporter
EES41_RS32515	COG2197	response regulator
EES41_RS32520	COG4585	Histidine kinase
EES41_RS32545	COG0277	FAD linked oxidase domain protein
EES41_RS32550	COG2226	methyltransferase
EES41_RS32560	COG4264	IucA IucC family
EES41_RS32575	COG1191	sigma factor activity
EES41_RS32580	COG0517	IMP dehydrogenase activity
EES41_RS32580	COG4175	Glycine betaine
EES41_RS32590	COG2409	Drug exporters of the RND superfamily
EES41_RS32595	COG4585	Histidine kinase
EES41_RS32600	COG2197	response regulator
EES41_RS32630	COG0583	DNA-binding transcription factor activity
EES41_RS32635	COG0477	Major facilitator Superfamily
EES41_RS32645	COG3226	Transcriptional regulator
EES41_RS32705	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EES41_RS32705	COG1796	DNA polymerase
EES41_RS32735	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EES41_RS32745	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EES41_RS32750	COG1278	Cold shock
EES41_RS32765	COG1846	Transcriptional regulator
EES41_RS32770	COG1764	response to oxidative stress
EES41_RS32795	COG2197	response regulator
EES41_RS32825	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EES41_RS32830	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EES41_RS32870	COG2207	Transcriptional regulator
EES41_RS32875	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EES41_RS32880	COG1714	RDD family
EES41_RS32970	COG0318	PFAM AMP-dependent synthetase and ligase
EES41_RS33030	COG1396	sequence-specific DNA binding
EES41_RS33030	COG1917	Cupin 2, conserved barrel domain protein
EES41_RS33045	COG2124	cytochrome p450
EES41_RS33060	COG3973	AAA domain
EES41_RS33085	COG3629	intracellular signal transduction
EES41_RS33085	COG3903	Transcriptional regulator
EES41_RS33090	COG2197	response regulator
EES41_RS33095	COG3629	intracellular signal transduction
EES41_RS33095	COG3903	Transcriptional regulator
EES41_RS33140	COG4941	Belongs to the sigma-70 factor family
EES41_RS33145	COG3795	YCII-related domain
EES41_RS33165	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EES41_RS33185	COG0671	phosphoesterase, PA-phosphatase related
EES41_RS33190	COG2226	methyltransferase
EES41_RS33210	COG1028	Short-chain dehydrogenase reductase Sdr
EES41_RS33235	COG2319	Wd-40 repeat
EES41_RS33235	COG4249	Peptidase C14 caspase catalytic subunit p20
EES41_RS33250	COG0640	Transcriptional regulator
EES41_RS33330	COG4585	Histidine kinase
EES41_RS33335	COG2197	response regulator
EES41_RS33345	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EES41_RS33355	COG1960	acyl-CoA dehydrogenase activity
EES41_RS33425	COG0464	growth
EES41_RS33450	COG2814	Major facilitator Superfamily
EES41_RS33475	COG1028	Short-chain dehydrogenase reductase Sdr
EES41_RS33495	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EES41_RS33505	COG1309	transcriptional regulator
EES41_RS33510	COG0667	Aldo Keto reductase
EES41_RS33605	COG2268	Band 7 protein
EES41_RS33640	COG0745	RESPONSE REGULATOR receiver
EES41_RS33645	COG5002	protein histidine kinase activity
EES41_RS33665	COG2015	COG2015, Alkyl sulfatase and related hydrolases
EES41_RS33680	COG3387	PFAM Glycoside hydrolase 15-related
EES41_RS33735	COG1191	sigma factor activity
EES41_RS33770	COG0714	Associated with various cellular activities
EES41_RS33810	COG1278	Cold shock
EES41_RS33815	COG0513	Belongs to the DEAD box helicase family
EES41_RS33840	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EES41_RS33870	COG2207	Transcriptional regulator
EES41_RS33875	COG1028	Short-chain dehydrogenase reductase Sdr
EES41_RS33885	COG3631	Ketosteroid isomerase-related protein
EES41_RS33890	COG0702	epimerase
EES41_RS33900	COG4977	sequence-specific DNA binding
EES41_RS33925	COG0739	heme binding
EES41_RS33925	COG1196	nuclear chromosome segregation
EES41_RS33925	COG0741	lytic transglycosylase activity
EES41_RS33955	COG2340	Cysteine-rich secretory protein family
EES41_RS33970	COG0667	Aldo Keto reductase
EES41_RS33995	COG0456	acetyltransferase
EES41_RS34000	COG1024	Enoyl-CoA hydratase
EES41_RS34015	COG4977	sequence-specific DNA binding
EES41_RS34030	COG4221	oxidoreductase activity
EES41_RS34045	COG1309	transcriptional regulator
EES41_RS34055	COG3548	integral membrane protein
EES41_RS34080	COG1051	belongs to the nudix hydrolase family
EES41_RS34085	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EES41_RS34090	COG2814	Major facilitator Superfamily
EES41_RS34105	COG1028	Short-chain dehydrogenase reductase Sdr
EES41_RS34130	COG2124	cytochrome p450
EES41_RS34210	COG0784	Response regulator, receiver
EES41_RS34215	COG4251	negative regulation of phosphorylation
EES41_RS34235	COG0165	Argininosuccinate lyase
EES41_RS34245	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EES41_RS34280	COG2423	ornithine cyclodeaminase activity
EES41_RS34295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EES41_RS34360	COG0395	ABC-type sugar transport system, permease component
EES41_RS34365	COG1175	transmembrane transport
EES41_RS34370	COG1653	transport
EES41_RS34375	COG0366	Alpha amylase catalytic
EES41_RS34380	COG1653	transport
EES41_RS34390	COG1136	(ABC) transporter
EES41_RS34415	COG0583	DNA-binding transcription factor activity
EES41_RS34420	COG0596	Alpha beta hydrolase
EES41_RS34465	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
EES41_RS34475	COG2890	protein-(glutamine-N5) methyltransferase activity
EES41_RS34490	COG0069	glutamate synthase activity
EES41_RS34495	COG0028	Belongs to the TPP enzyme family
EES41_RS34510	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
EES41_RS34525	COG2326	polyphosphate kinase activity
EES41_RS34530	COG1295	ribonuclease BN
EES41_RS34565	COG0789	Transcriptional regulator
EES41_RS34590	COG0671	phosphoesterase, PA-phosphatase related
EES41_RS34615	COG3655	Transcriptional regulator
EES41_RS34655	COG0583	DNA-binding transcription factor activity
EES41_RS34675	COG3845	ABC transporter
EES41_RS34720	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EES41_RS34795	COG0596	Alpha beta hydrolase
EES41_RS34800	COG0596	Alpha beta hydrolase
EES41_RS34830	COG0586	Pfam SNARE associated Golgi protein
EES41_RS34835	COG0671	phosphoesterase, PA-phosphatase related
EES41_RS34850	COG2837	iron assimilation
EES41_RS34880	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EES41_RS34925	COG1733	regulation of RNA biosynthetic process
EES41_RS34960	COG1846	Transcriptional regulator
EES41_RS34965	COG2409	Drug exporters of the RND superfamily
EES41_RS34990	COG0583	DNA-binding transcription factor activity
EES41_RS35005	COG0784	Response regulator, receiver
EES41_RS35010	COG4251	negative regulation of phosphorylation
EES41_RS35070	COG2197	response regulator
EES41_RS35145	COG2945	thiolester hydrolase activity
EES41_RS35145	COG0596	Alpha beta hydrolase
EES41_RS35210	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EES41_RS35260	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
EES41_RS35290	COG2326	polyphosphate kinase activity
EES41_RS35300	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EES41_RS35305	COG0640	Transcriptional regulator
EES41_RS35320	COG1247	-acetyltransferase
EES41_RS35325	COG0640	Transcriptional regulator
EES41_RS35375	COG2353	YceI-like domain
EES41_RS35435	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EES41_RS35440	COG0596	Alpha beta hydrolase
EES41_RS35460	COG0765	amino acid transport
EES41_RS35475	COG1028	Short-chain dehydrogenase reductase Sdr
EES41_RS35645	COG1028	Short-chain dehydrogenase reductase Sdr
EES41_RS35650	COG3021	interspecies interaction between organisms
EES41_RS35675	COG0384	phenazine biosynthesis protein PhzF
EES41_RS35685	COG0583	DNA-binding transcription factor activity
EES41_RS35760	COG0667	Aldo Keto reductase
EES41_RS35770	COG2226	methyltransferase
EES41_RS35820	COG1733	regulation of RNA biosynthetic process
EES41_RS35880	COG0783	Belongs to the Dps family
EES41_RS36015	COG1366	Belongs to the anti-sigma-factor antagonist family
EES41_RS36040	COG2814	Major facilitator Superfamily
EES41_RS36045	COG0640	Transcriptional regulator
EES41_RS36060	COG0640	Transcriptional regulator
EES41_RS36075	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EES41_RS36090	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EES41_RS36110	COG0640	Transcriptional regulator
EES41_RS36115	COG1316	TRANSCRIPTIONal
EES41_RS36235	COG1309	transcriptional regulator
EES41_RS36240	COG0604	alcohol dehydrogenase
EES41_RS36240	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EES41_RS36240	COG3321	synthase
EES41_RS36240	COG4221	oxidoreductase activity
EES41_RS36375	COG3883	PFAM NLP P60 protein
EES41_RS36375	COG0791	NLP P60 protein
EES41_RS36420	COG2226	methyltransferase
EES41_RS36470	COG0438	transferase activity, transferring glycosyl groups
EES41_RS36485	COG1215	transferase activity, transferring glycosyl groups
EES41_RS36535	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EES41_RS36540	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EES41_RS36680	COG1585	Membrane protein implicated in regulation of membrane protease activity
EES41_RS36740	COG0535	radical SAM domain protein
EES41_RS36800	COG1278	Cold shock
EES41_RS36860	COG4974	Belongs to the 'phage' integrase family
EES41_RS36885	COG1484	DNA-dependent DNA replication
EES41_RS36900	COG0515	serine threonine protein kinase
EES41_RS36900	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EES41_RS36980	COG1278	Cold shock
EES41_RS37035	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EES41_RS37040	COG0673	inositol 2-dehydrogenase activity
EES41_RS37045	COG3718	enzyme involved in inositol metabolism
EES41_RS37285	COG0667	Aldo Keto reductase
EES41_RS37295	COG2030	dehydratase
EES41_RS37305	COG4770	biotin carboxylase activity
EES41_RS37310	COG3629	intracellular signal transduction
EES41_RS37330	COG1309	transcriptional regulator
EES41_RS37355	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EES41_RS37370	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EES41_RS37375	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EES41_RS37475	COG1131	(ABC) transporter
EES41_RS37485	COG4585	Histidine kinase
EES41_RS37490	COG2197	response regulator
EES41_RS37525	COG1505	serine-type exopeptidase activity
EES41_RS37640	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EES41_RS37645	COG0823	Involved in the tonB-independent uptake of proteins
EES41_RS37645	COG1506	peptidase
EES41_RS37705	COG1475	DNA binding
EES41_RS37710	COG1192	Involved in chromosome partitioning
EES41_RS37730	COG3328	transposase activity
EES41_RS37750	COG0596	Alpha beta hydrolase
EES41_RS37755	COG2318	DinB family
EES41_RS37770	COG0702	epimerase
EES41_RS37785	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EES41_RS37790	COG0318	PFAM AMP-dependent synthetase and ligase
EES41_RS37810	COG1309	transcriptional regulator
EES41_RS37860	COG1902	pentaerythritol trinitrate reductase activity
EES41_RS37885	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EES41_RS37900	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
EES41_RS37905	COG0512	Glutamine amidotransferase of anthranilate synthase
EES41_RS37905	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EES41_RS37915	COG0318	PFAM AMP-dependent synthetase and ligase
EES41_RS37930	COG0277	FAD linked oxidase domain protein
EES41_RS37940	COG0318	PFAM AMP-dependent synthetase and ligase
EES41_RS37970	COG1773	rubredoxin
EES41_RS37980	COG0477	Major facilitator Superfamily
EES41_RS37990	COG1028	Short-chain dehydrogenase reductase Sdr
EES41_RS38010	COG0745	RESPONSE REGULATOR receiver
EES41_RS38025	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EES41_RS38030	COG1410	methionine synthase
EES41_RS38030	COG0646	methionine synthase
EES41_RS38050	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EES41_RS38055	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EES41_RS38060	COG2814	Major facilitator Superfamily
EES41_RS38080	COG0154	amidase activity
EES41_RS38160	COG2814	Major facilitator Superfamily
EES41_RS38255	COG2850	peptidyl-arginine hydroxylation
EES41_RS38275	COG4257	antibiotic catabolic process
EES41_RS38280	COG0110	maltose O-acetyltransferase activity
EES41_RS38285	COG0583	DNA-binding transcription factor activity
EES41_RS38290	COG0596	Alpha beta hydrolase
EES41_RS38375	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EES41_RS38395	COG3250	beta-galactosidase activity
EES41_RS38420	COG4106	trans-aconitate 2-methyltransferase activity
EES41_RS38515	COG4221	oxidoreductase activity
EES41_RS38535	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EES41_RS38555	COG0110	maltose O-acetyltransferase activity
EES41_RS38570	COG0318	PFAM AMP-dependent synthetase and ligase
EES41_RS38605	COG4555	ABC transporter
EES41_RS38655	COG3629	intracellular signal transduction
EES41_RS38655	COG3903	Transcriptional regulator
EES41_RS38670	COG4106	trans-aconitate 2-methyltransferase activity
EES41_RS38710	COG2084	Dehydrogenase
EES41_RS38715	COG1733	regulation of RNA biosynthetic process
EES41_RS38745	COG0667	Aldo Keto reductase
EES41_RS38755	COG0395	ABC-type sugar transport system, permease component
EES41_RS38775	COG1349	DNA-binding transcription factor activity
EES41_RS38780	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EES41_RS38795	COG1349	DNA-binding transcription factor activity
EES41_RS38800	COG1172	Belongs to the binding-protein-dependent transport system permease family
EES41_RS38805	COG1129	ABC transporter
EES41_RS38810	COG1879	ABC-type sugar transport system periplasmic component
EES41_RS38830	COG4948	Mandelate Racemase Muconate Lactonizing
EES41_RS38835	COG1028	Short-chain dehydrogenase reductase Sdr
EES41_RS38845	COG0800	Aldolase
EES41_RS38855	COG1940	carbohydrate kinase activity
EES41_RS38860	COG1609	Transcriptional regulator
EES41_RS38905	COG1686	Belongs to the peptidase S11 family
EES41_RS38950	COG1846	Transcriptional regulator
EES41_RS38955	COG1902	pentaerythritol trinitrate reductase activity
EES41_RS38960	COG0077	Prephenate dehydratase
EES41_RS38970	COG1028	Short-chain dehydrogenase reductase Sdr
EES41_RS38975	COG1028	Short-chain dehydrogenase reductase Sdr
EES41_RS38980	COG2814	Major facilitator Superfamily
EES41_RS38985	COG0436	Aminotransferase
EES41_RS38995	COG1316	TRANSCRIPTIONal
EES41_RS39010	COG0300	oxidoreductase activity
EES41_RS39015	COG1309	transcriptional regulator
EES41_RS39105	COG0598	Magnesium transport protein CorA
EES41_RS39130	COG0702	epimerase
EES41_RS39135	COG1733	regulation of RNA biosynthetic process
EES41_RS39140	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EES41_RS39145	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
EES41_RS39150	COG2080	2 iron, 2 sulfur cluster binding
EES41_RS39195	COG1028	Short-chain dehydrogenase reductase Sdr
EES41_RS39205	COG1652	LysM domain
EES41_RS39250	COG0305	Participates in initiation and elongation during chromosome replication
EES41_RS39275	COG0604	alcohol dehydrogenase
EES41_RS39275	COG3321	synthase
EES41_RS39275	COG1028	Short-chain dehydrogenase reductase Sdr
EES41_RS39310	COG0436	Aminotransferase
EES41_RS39315	COG2423	ornithine cyclodeaminase activity
EES41_RS39335	COG1595	DNA-templated transcription, initiation
EES41_RS39375	COG3293	Transposase
EES41_RS39415	COG1028	Short-chain dehydrogenase reductase Sdr
EES41_RS39510	COG3328	transposase activity
EES41_RS39525	COG1228	amidohydrolase
EES41_RS39525	COG1228	amidohydrolase
EES41_RS39540	COG1404	Belongs to the peptidase S8 family
EES41_RS39570	COG1131	(ABC) transporter
EES41_RS39610	COG2161	toxin-antitoxin pair type II binding
EES41_RS39625	COG0305	Participates in initiation and elongation during chromosome replication
EES41_RS39675	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EES41_RS39680	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EES41_RS39685	COG0105	UTP biosynthetic process
EES41_RS39695	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EES41_RS39735	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EES41_RS39750	COG0641	radical SAM
EES41_RS39905	COG2801	Transposase and inactivated derivatives
EES41_RS39955	COG1475	DNA binding
EES41_RS40135	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EES41_RS40135	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EES41_RS40155	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
EES41_RS40180	COG1857	crispr-associated protein
EES41_RS40195	COG1518	maintenance of DNA repeat elements
EES41_RS40200	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EES41_RS40210	COG2801	Transposase and inactivated derivatives
EES41_RS40285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EES41_RS40285	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EES41_RS40290	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EES41_RS40295	COG0730	response to heat
EES41_RS40305	COG1937	Protein conserved in bacteria
EES41_RS40315	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EES41_RS40320	COG0587	DNA-directed DNA polymerase activity
EES41_RS40325	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EES41_RS40345	COG0789	Transcriptional regulator
EES41_RS40360	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EES41_RS40370	COG1309	transcriptional regulator
EES41_RS40375	COG2267	carboxylic ester hydrolase activity
EES41_RS40505	COG3321	synthase
EES41_RS40505	COG0604	alcohol dehydrogenase
EES41_RS40520	COG2124	cytochrome p450
EES41_RS40525	COG2207	Transcriptional regulator
EES41_RS40525	COG0662	Cupin 2, conserved barrel domain protein
EES41_RS40575	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EES41_RS40580	COG0596	Alpha beta hydrolase
EES41_RS40600	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
EES41_RS40610	COG0159	tryptophan synthase activity
EES41_RS40615	COG0134	indole-3-glycerol-phosphate synthase activity
EES41_RS40620	COG0477	Major facilitator Superfamily
EES41_RS40625	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EES41_RS40670	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EES41_RS40700	COG2226	methyltransferase
EES41_RS40725	COG1045	serine acetyltransferase
EES41_RS40745	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EES41_RS40770	COG0318	PFAM AMP-dependent synthetase and ligase
EES41_RS40820	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EES41_RS40835	COG0367	asparagine synthase
EES41_RS40865	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EES41_RS40975	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EES41_RS41010	COG2226	methyltransferase
EES41_RS41015	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity