locus-tag	class	description
AS97_RS00285	COG1846	Transcriptional regulator
AS97_RS00295	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AS97_RS00315	COG1522	sequence-specific DNA binding
AS97_RS00330	COG4166	transmembrane transport
AS97_RS00345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AS97_RS00355	COG4608	Belongs to the ABC transporter superfamily
AS97_RS00360	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AS97_RS00365	COG0683	leucine binding
AS97_RS00390	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS00420	COG0559	Belongs to the binding-protein-dependent transport system permease family
AS97_RS00445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS97_RS00450	COG0508	dehydrogenase complex catalyzes the overall conversion of
AS97_RS00455	COG0022	dehydrogenase e1 component
AS97_RS00470	COG1960	acyl-CoA dehydrogenase activity
AS97_RS00475	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AS97_RS00480	COG1522	sequence-specific DNA binding
AS97_RS00550	COG0318	PFAM AMP-dependent synthetase and ligase
AS97_RS00560	COG3246	L-lysine catabolic process to acetate
AS97_RS00570	COG2175	clavaminate synthase activity
AS97_RS00585	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AS97_RS00695	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AS97_RS00715	COG0179	Fumarylacetoacetate (FAA) hydrolase
AS97_RS00725	COG1063	alcohol dehydrogenase
AS97_RS00745	COG1802	Transcriptional regulator
AS97_RS00755	COG0318	PFAM AMP-dependent synthetase and ligase
AS97_RS00790	COG1120	ATPase activity
AS97_RS00795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS97_RS00805	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AS97_RS00880	COG0318	PFAM AMP-dependent synthetase and ligase
AS97_RS00925	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AS97_RS00975	COG4221	oxidoreductase activity
AS97_RS01010	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS01015	COG1309	transcriptional regulator
AS97_RS01035	COG4566	intracellular signal transduction
AS97_RS01060	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AS97_RS01070	COG0730	response to heat
AS97_RS01125	COG1012	belongs to the aldehyde dehydrogenase family
AS97_RS01130	COG1012	belongs to the aldehyde dehydrogenase family
AS97_RS01135	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AS97_RS01140	COG1172	Belongs to the binding-protein-dependent transport system permease family
AS97_RS01145	COG1129	ABC transporter
AS97_RS01155	COG1069	ribulokinase activity
AS97_RS01160	COG1063	alcohol dehydrogenase
AS97_RS01165	COG1879	ABC-type sugar transport system periplasmic component
AS97_RS01185	COG5492	domain, Protein
AS97_RS01190	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
AS97_RS01195	COG0395	ABC-type sugar transport system, permease component
AS97_RS01200	COG1175	transmembrane transport
AS97_RS01315	COG0395	ABC-type sugar transport system, permease component
AS97_RS01330	COG1609	Transcriptional regulator
AS97_RS01385	COG1733	regulation of RNA biosynthetic process
AS97_RS01395	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AS97_RS01400	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AS97_RS01405	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AS97_RS01435	COG1454	alcohol dehydrogenase
AS97_RS01480	COG0596	Alpha beta hydrolase
AS97_RS01485	COG1335	isochorismatase
AS97_RS01515	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AS97_RS01520	COG2309	aminopeptidase activity
AS97_RS01575	COG1175	transmembrane transport
AS97_RS01580	COG0395	ABC-type sugar transport system, permease component
AS97_RS01595	COG3661	Belongs to the glycosyl hydrolase 67 family
AS97_RS01610	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AS97_RS01630	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AS97_RS01640	COG0747	negative chemotaxis
AS97_RS01645	COG0601	transmembrane transport
AS97_RS01650	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AS97_RS01655	COG0444	Belongs to the ABC transporter superfamily
AS97_RS01660	COG4608	Belongs to the ABC transporter superfamily
AS97_RS01700	COG1891	lyase activity
AS97_RS01715	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AS97_RS01725	COG1733	regulation of RNA biosynthetic process
AS97_RS01755	COG0655	NAD(P)H dehydrogenase (quinone) activity
AS97_RS01775	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AS97_RS01785	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS01790	COG1012	belongs to the aldehyde dehydrogenase family
AS97_RS01795	COG4608	Belongs to the ABC transporter superfamily
AS97_RS01805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AS97_RS01810	COG0601	transmembrane transport
AS97_RS01820	COG0473	3-isopropylmalate dehydrogenase activity
AS97_RS01830	COG2186	Transcriptional regulator
AS97_RS01840	COG0789	Transcriptional regulator
AS97_RS01860	COG1073	alpha beta
AS97_RS01910	COG2226	methyltransferase
AS97_RS01945	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AS97_RS01970	COG4977	sequence-specific DNA binding
AS97_RS02000	COG1733	regulation of RNA biosynthetic process
AS97_RS02025	COG0739	heme binding
AS97_RS02075	COG2084	Dehydrogenase
AS97_RS02080	COG3395	kinase activity
AS97_RS02095	COG3622	Belongs to the hyi family
AS97_RS02100	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AS97_RS02115	COG2318	DinB family
AS97_RS02120	COG0667	Aldo Keto reductase
AS97_RS02145	COG1959	2 iron, 2 sulfur cluster binding
AS97_RS02155	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AS97_RS02165	COG2345	Transcriptional regulator
AS97_RS02170	COG0789	Transcriptional regulator
AS97_RS02215	COG1982	Orn Lys Arg decarboxylase major
AS97_RS02245	COG2080	2 iron, 2 sulfur cluster binding
AS97_RS02250	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AS97_RS02255	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AS97_RS02270	COG2124	cytochrome p450
AS97_RS02300	COG0596	Alpha beta hydrolase
AS97_RS02310	COG1309	transcriptional regulator
AS97_RS02335	COG0726	polysaccharide deacetylase
AS97_RS02355	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AS97_RS02405	COG3321	synthase
AS97_RS02405	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS02405	COG0604	alcohol dehydrogenase
AS97_RS02415	COG0328	RNA-DNA hybrid ribonuclease activity
AS97_RS02420	COG2356	endonuclease I
AS97_RS02445	COG1959	2 iron, 2 sulfur cluster binding
AS97_RS02450	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS02480	COG1051	belongs to the nudix hydrolase family
AS97_RS02505	COG3511	phospholipase C
AS97_RS02545	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AS97_RS02595	COG1357	PFAM Pentapeptide repeats (8 copies)
AS97_RS02605	COG0306	phosphate transporter
AS97_RS02625	COG2175	clavaminate synthase activity
AS97_RS02630	COG3629	intracellular signal transduction
AS97_RS02630	COG3903	Transcriptional regulator
AS97_RS02645	COG0596	Alpha beta hydrolase
AS97_RS02655	COG0114	fumarate hydratase activity
AS97_RS02660	COG0726	polysaccharide deacetylase
AS97_RS02675	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AS97_RS02680	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AS97_RS02685	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AS97_RS02695	COG3290	protein histidine kinase activity
AS97_RS02700	COG4565	transcriptional regulatory protein
AS97_RS02710	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AS97_RS02735	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AS97_RS02740	COG2376	Dihydroxyacetone kinase
AS97_RS02745	COG2376	Dihydroxyacetone kinase
AS97_RS02750	COG3594	Acyltransferase
AS97_RS02755	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AS97_RS02785	COG0747	negative chemotaxis
AS97_RS02810	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS97_RS02820	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AS97_RS02825	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AS97_RS02830	COG2080	2 iron, 2 sulfur cluster binding
AS97_RS02835	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AS97_RS02925	COG0412	Dienelactone hydrolase
AS97_RS02945	COG0326	Molecular chaperone. Has ATPase activity
AS97_RS03000	COG0604	alcohol dehydrogenase
AS97_RS03020	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AS97_RS03030	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AS97_RS03050	COG0018	arginyl-trna synthetase
AS97_RS03055	COG0739	heme binding
AS97_RS03065	COG2175	clavaminate synthase activity
AS97_RS03070	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AS97_RS03080	COG0109	protoheme IX farnesyltransferase activity
AS97_RS03090	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AS97_RS03115	COG0668	transmembrane transport
AS97_RS03145	COG3387	PFAM Glycoside hydrolase 15-related
AS97_RS03160	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AS97_RS03170	COG0477	Major facilitator Superfamily
AS97_RS03185	COG3537	Alpha-1,2-mannosidase
AS97_RS03220	COG4948	Mandelate Racemase Muconate Lactonizing
AS97_RS03225	COG2610	gluconate transmembrane transporter activity
AS97_RS03255	COG1414	Transcriptional regulator
AS97_RS03260	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AS97_RS03270	COG1968	undecaprenyl-diphosphatase activity
AS97_RS03275	COG1902	pentaerythritol trinitrate reductase activity
AS97_RS03280	COG1595	DNA-templated transcription, initiation
AS97_RS03305	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AS97_RS03315	COG4221	oxidoreductase activity
AS97_RS03380	COG1309	transcriptional regulator
AS97_RS03390	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AS97_RS03395	COG3291	Pkd domain containing protein
AS97_RS03395	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AS97_RS03455	COG0435	Glutathione S-transferase
AS97_RS03500	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS03565	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AS97_RS03575	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS03580	COG0667	Aldo Keto reductase
AS97_RS03585	COG0604	alcohol dehydrogenase
AS97_RS03585	COG3321	synthase
AS97_RS03600	COG1819	glycosyl
AS97_RS03615	COG0604	alcohol dehydrogenase
AS97_RS03615	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS03615	COG3321	synthase
AS97_RS03625	COG0488	(ABC) transporter
AS97_RS03650	COG3509	depolymerase
AS97_RS03665	COG1012	belongs to the aldehyde dehydrogenase family
AS97_RS03690	COG3835	regulator
AS97_RS03695	COG2226	methyltransferase
AS97_RS03705	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AS97_RS03715	COG2271	Major facilitator Superfamily
AS97_RS03770	COG0701	Predicted permease
AS97_RS03795	COG4585	Histidine kinase
AS97_RS03800	COG2197	response regulator
AS97_RS03820	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS03875	COG0531	amino acid
AS97_RS03930	COG3119	arylsulfatase activity
AS97_RS03935	COG3507	Belongs to the glycosyl hydrolase 43 family
AS97_RS03955	COG1175	transmembrane transport
AS97_RS03960	COG0395	ABC-type sugar transport system, permease component
AS97_RS03965	COG1609	Transcriptional regulator
AS97_RS03970	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AS97_RS03995	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS97_RS04010	COG2226	methyltransferase
AS97_RS04045	COG2197	response regulator
AS97_RS04110	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS97_RS04150	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AS97_RS04185	COG0542	response to heat
AS97_RS04195	COG0515	serine threonine protein kinase
AS97_RS04195	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AS97_RS04230	COG0789	Transcriptional regulator
AS97_RS04245	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AS97_RS04260	COG1695	Transcriptional regulator
AS97_RS04285	COG3634	alkyl hydroperoxide reductase activity
AS97_RS04295	COG3290	protein histidine kinase activity
AS97_RS04300	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AS97_RS04320	COG1063	alcohol dehydrogenase
AS97_RS04330	COG2072	flavoprotein involved in K transport
AS97_RS04345	COG1053	succinate dehydrogenase
AS97_RS04350	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AS97_RS04400	COG2197	response regulator
AS97_RS04415	COG5006	permease, DMT superfamily
AS97_RS04435	COG3467	pyridoxamine 5'-phosphate
AS97_RS04590	COG0587	DNA-directed DNA polymerase activity
AS97_RS04595	COG1609	Transcriptional regulator
AS97_RS04605	COG1175	transmembrane transport
AS97_RS04610	COG0395	ABC-type sugar transport system, permease component
AS97_RS04615	COG0366	Alpha amylase catalytic
AS97_RS04625	COG0137	argininosuccinate synthase activity
AS97_RS04635	COG4948	Mandelate Racemase Muconate Lactonizing
AS97_RS04660	COG2353	YceI-like domain
AS97_RS04675	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
AS97_RS04680	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AS97_RS04695	COG0277	FAD linked oxidase domain protein
AS97_RS04710	COG3046	protein related to deoxyribodipyrimidine photolyase
AS97_RS04720	COG4585	Histidine kinase
AS97_RS04725	COG2197	response regulator
AS97_RS04735	COG0577	efflux transmembrane transporter activity
AS97_RS04735	COG1136	(ABC) transporter
AS97_RS04740	COG1136	(ABC) transporter
AS97_RS04745	COG2197	response regulator
AS97_RS04750	COG4585	Histidine kinase
AS97_RS04775	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS04805	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS04845	COG1959	2 iron, 2 sulfur cluster binding
AS97_RS04880	COG1316	TRANSCRIPTIONal
AS97_RS04885	COG2261	transglycosylase associated protein
AS97_RS04895	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS04905	COG1819	glycosyl
AS97_RS04910	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AS97_RS04915	COG1309	transcriptional regulator
AS97_RS04990	COG1222	aaa ATPase
AS97_RS05025	COG0583	DNA-binding transcription factor activity
AS97_RS05035	COG2318	DinB family
AS97_RS05045	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AS97_RS05070	COG0640	Transcriptional regulator
AS97_RS05090	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AS97_RS05100	COG0254	rRNA binding
AS97_RS05105	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AS97_RS05110	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AS97_RS05115	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AS97_RS05120	COG1024	Enoyl-CoA hydratase
AS97_RS05135	COG0723	plastoquinol--plastocyanin reductase activity
AS97_RS05135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AS97_RS05170	COG1113	amino acid transport
AS97_RS05175	COG2186	Transcriptional regulator
AS97_RS05190	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AS97_RS05195	COG0673	inositol 2-dehydrogenase activity
AS97_RS05210	COG2318	DinB family
AS97_RS05250	COG2378	regulation of single-species biofilm formation
AS97_RS05260	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AS97_RS05290	COG1846	Transcriptional regulator
AS97_RS05295	COG3387	PFAM Glycoside hydrolase 15-related
AS97_RS05305	COG0028	Belongs to the TPP enzyme family
AS97_RS05310	COG0277	FAD linked oxidase domain protein
AS97_RS05310	COG0247	lactate metabolic process
AS97_RS05315	COG2755	lipolytic protein G-D-S-L family
AS97_RS05325	COG3655	Transcriptional regulator
AS97_RS05335	COG0494	nUDIX hydrolase
AS97_RS05345	COG0318	PFAM AMP-dependent synthetase and ligase
AS97_RS05350	COG0183	Belongs to the thiolase family
AS97_RS05425	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AS97_RS05435	COG0583	DNA-binding transcription factor activity
AS97_RS05460	COG2072	flavoprotein involved in K transport
AS97_RS05490	COG0384	phenazine biosynthesis protein PhzF
AS97_RS05515	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AS97_RS05525	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS05540	COG3795	YCII-related domain
AS97_RS05545	COG4941	Belongs to the sigma-70 factor family
AS97_RS05555	COG0583	DNA-binding transcription factor activity
AS97_RS05560	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS05570	COG0477	Major facilitator Superfamily
AS97_RS05580	COG2801	Transposase and inactivated derivatives
AS97_RS05580	COG3415	Transposase
AS97_RS05595	COG0488	(ABC) transporter
AS97_RS05615	COG0583	DNA-binding transcription factor activity
AS97_RS05620	COG0697	spore germination
AS97_RS05685	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AS97_RS05685	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AS97_RS05715	COG1716	ATPase activity
AS97_RS05735	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AS97_RS05760	COG2190	(PTS) system
AS97_RS05765	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AS97_RS05780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS97_RS05785	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AS97_RS05800	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
AS97_RS05805	COG1177	transmembrane transport
AS97_RS05810	COG1176	ABC-type spermidine putrescine transport system, permease component I
AS97_RS05815	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AS97_RS05820	COG3842	ATPase activity
AS97_RS05830	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AS97_RS05835	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AS97_RS05840	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AS97_RS05855	COG2018	Roadblock/LC7 domain
AS97_RS05875	COG2146	nitrite reductase [NAD(P)H] activity
AS97_RS05895	COG4638	Rieske (2fe-2S)
AS97_RS05900	COG1012	belongs to the aldehyde dehydrogenase family
AS97_RS05930	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AS97_RS05950	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AS97_RS05955	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AS97_RS05980	COG0438	transferase activity, transferring glycosyl groups
AS97_RS05985	COG0438	transferase activity, transferring glycosyl groups
AS97_RS06055	COG1024	Enoyl-CoA hydratase
AS97_RS06080	COG2070	2-Nitropropane dioxygenase
AS97_RS06090	COG2815	serine threonine protein kinase
AS97_RS06090	COG0515	serine threonine protein kinase
AS97_RS06115	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AS97_RS06120	COG4249	Peptidase C14 caspase catalytic subunit p20
AS97_RS06120	COG2319	Wd-40 repeat
AS97_RS06140	COG1960	acyl-CoA dehydrogenase activity
AS97_RS06150	COG2376	Dihydroxyacetone kinase
AS97_RS06155	COG1461	Dihydroxyacetone kinase
AS97_RS06160	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
AS97_RS06160	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AS97_RS06160	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AS97_RS06165	COG0142	geranyltranstransferase activity
AS97_RS06175	COG2124	cytochrome p450
AS97_RS06180	COG2124	cytochrome p450
AS97_RS06200	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS06205	COG1051	belongs to the nudix hydrolase family
AS97_RS06220	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AS97_RS06270	COG0464	growth
AS97_RS06280	COG1349	DNA-binding transcription factor activity
AS97_RS06315	COG1940	carbohydrate kinase activity
AS97_RS06345	COG2197	response regulator
AS97_RS06350	COG4585	Histidine kinase
AS97_RS06355	COG0445	tRNA wobble uridine modification
AS97_RS06365	COG1660	Displays ATPase and GTPase activities
AS97_RS06370	COG0395	ABC-type sugar transport system, permease component
AS97_RS06375	COG1175	transmembrane transport
AS97_RS06385	COG3345	alpha-galactosidase
AS97_RS06390	COG0515	serine threonine protein kinase
AS97_RS06390	COG2815	serine threonine protein kinase
AS97_RS06395	COG1940	carbohydrate kinase activity
AS97_RS06430	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AS97_RS06470	COG0584	glycerophosphoryl diester phosphodiesterase
AS97_RS06500	COG0671	phosphoesterase, PA-phosphatase related
AS97_RS06510	COG0456	acetyltransferase
AS97_RS06550	COG0367	asparagine synthase
AS97_RS06555	COG2814	Major facilitator Superfamily
AS97_RS06560	COG1120	ATPase activity
AS97_RS06565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS97_RS06595	COG0259	pyridoxamine-phosphate oxidase activity
AS97_RS06610	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AS97_RS06650	COG0493	'glutamate synthase
AS97_RS06655	COG2233	PERMEase
AS97_RS06660	COG0640	Transcriptional regulator
AS97_RS06665	COG1902	pentaerythritol trinitrate reductase activity
AS97_RS06675	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AS97_RS06695	COG2706	6-phosphogluconolactonase activity
AS97_RS06715	COG2027	D-alanyl-D-alanine carboxypeptidase
AS97_RS06720	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AS97_RS06730	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AS97_RS06735	COG1116	anion transmembrane transporter activity
AS97_RS06785	COG0738	Major facilitator superfamily
AS97_RS06810	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS97_RS06815	COG3119	arylsulfatase activity
AS97_RS06825	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AS97_RS06830	COG3940	Belongs to the glycosyl hydrolase 43 family
AS97_RS06835	COG0596	Alpha beta hydrolase
AS97_RS06845	COG3850	Histidine kinase
AS97_RS06850	COG0842	Transport permease protein
AS97_RS06860	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AS97_RS06900	COG0673	inositol 2-dehydrogenase activity
AS97_RS06910	COG1414	Transcriptional regulator
AS97_RS06930	COG2226	methyltransferase
AS97_RS06940	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AS97_RS06945	COG0659	secondary active sulfate transmembrane transporter activity
AS97_RS06960	COG0596	Alpha beta hydrolase
AS97_RS06970	COG1902	pentaerythritol trinitrate reductase activity
AS97_RS06975	COG1846	Transcriptional regulator
AS97_RS06980	COG1522	sequence-specific DNA binding
AS97_RS06985	COG1960	acyl-CoA dehydrogenase activity
AS97_RS07000	COG0583	DNA-binding transcription factor activity
AS97_RS07020	COG0656	L-ascorbic acid biosynthetic process
AS97_RS07030	COG2814	Major facilitator Superfamily
AS97_RS07055	COG1231	oxidoreductase activity
AS97_RS07060	COG3961	Belongs to the TPP enzyme family
AS97_RS07070	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS07080	COG0251	oxidation-reduction process
AS97_RS07105	COG0596	Alpha beta hydrolase
AS97_RS07125	COG1120	ATPase activity
AS97_RS07130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS97_RS07140	COG1595	DNA-templated transcription, initiation
AS97_RS07145	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AS97_RS07165	COG0515	serine threonine protein kinase
AS97_RS07200	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AS97_RS07255	COG1191	sigma factor activity
AS97_RS07270	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS07320	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AS97_RS07340	COG3469	chitinase activity
AS97_RS07385	COG3548	integral membrane protein
AS97_RS07395	COG1129	ABC transporter
AS97_RS07405	COG1172	Belongs to the binding-protein-dependent transport system permease family
AS97_RS07410	COG4948	Mandelate Racemase Muconate Lactonizing
AS97_RS07420	COG3469	chitinase activity
AS97_RS07435	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AS97_RS07440	COG0842	Transport permease protein
AS97_RS07440	COG1131	(ABC) transporter
AS97_RS07440	COG1716	ATPase activity
AS97_RS07505	COG0698	ribose 5-phosphate isomerase
AS97_RS07510	COG2376	Dihydroxyacetone kinase
AS97_RS07525	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AS97_RS07530	COG1349	DNA-binding transcription factor activity
AS97_RS07535	COG2814	Major facilitator Superfamily
AS97_RS07555	COG0473	3-isopropylmalate dehydrogenase activity
AS97_RS07555	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AS97_RS07560	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS97_RS07570	COG0574	Belongs to the PEP-utilizing enzyme family
AS97_RS07570	COG3848	Pyruvate phosphate dikinase
AS97_RS07585	COG0142	geranyltranstransferase activity
AS97_RS07610	COG0009	L-threonylcarbamoyladenylate synthase
AS97_RS07625	COG1309	transcriptional regulator
AS97_RS07660	COG0702	epimerase
AS97_RS07670	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AS97_RS07675	COG0667	Aldo Keto reductase
AS97_RS07685	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AS97_RS07725	COG2130	NADP-dependent
AS97_RS07740	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS07755	COG2207	Transcriptional regulator
AS97_RS07760	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS07780	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS07805	COG0154	amidase activity
AS97_RS07845	COG0477	Major facilitator Superfamily
AS97_RS07850	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS07865	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AS97_RS07895	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AS97_RS07895	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AS97_RS07895	COG1703	isobutyryl-CoA mutase activity
AS97_RS07900	COG2226	methyltransferase
AS97_RS07940	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AS97_RS07945	COG0277	FAD linked oxidase domain protein
AS97_RS07965	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS07965	COG3321	synthase
AS97_RS07965	COG0604	alcohol dehydrogenase
AS97_RS07970	COG1733	regulation of RNA biosynthetic process
AS97_RS07985	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AS97_RS08040	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AS97_RS08055	COG4310	Domain of unknown function (DUF2172)
AS97_RS08065	COG1215	transferase activity, transferring glycosyl groups
AS97_RS08075	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
AS97_RS08080	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AS97_RS08110	COG1476	TRANSCRIPTIONal
AS97_RS08120	COG1408	metallophosphoesterase
AS97_RS08125	COG2217	Heavy metal translocating P-type atpase
AS97_RS08160	COG0318	PFAM AMP-dependent synthetase and ligase
AS97_RS08185	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AS97_RS08190	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AS97_RS08195	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AS97_RS08205	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS08220	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AS97_RS08225	COG3959	Transketolase, thiamine diphosphate binding domain
AS97_RS08230	COG3958	Transketolase
AS97_RS08260	COG1250	3-hydroxyacyl-CoA dehydrogenase
AS97_RS08270	COG1960	acyl-CoA dehydrogenase activity
AS97_RS08280	COG2226	methyltransferase
AS97_RS08285	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS08290	COG1611	Belongs to the LOG family
AS97_RS08310	COG0513	Belongs to the DEAD box helicase family
AS97_RS08315	COG1278	Cold shock
AS97_RS08325	COG2205	protein histidine kinase activity
AS97_RS08330	COG0745	RESPONSE REGULATOR receiver
AS97_RS08340	COG0516	GMP reductase activity
AS97_RS08340	COG0517	IMP dehydrogenase activity
AS97_RS08345	COG1902	pentaerythritol trinitrate reductase activity
AS97_RS08355	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS08360	COG0583	DNA-binding transcription factor activity
AS97_RS08365	COG2318	DinB family
AS97_RS08375	COG0640	Transcriptional regulator
AS97_RS08380	COG0798	PFAM Bile acid sodium symporter
AS97_RS08385	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AS97_RS08450	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
AS97_RS08500	COG2326	polyphosphate kinase activity
AS97_RS08510	COG0589	response to stress
AS97_RS08515	COG2239	Acts as a magnesium transporter
AS97_RS08530	COG0309	Hydrogenase expression formation protein (HypE)
AS97_RS08540	COG0298	carbon dioxide binding
AS97_RS08545	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AS97_RS08585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS97_RS08590	COG2807	transmembrane transport
AS97_RS08600	COG0563	adenylate kinase activity
AS97_RS08615	COG0318	PFAM AMP-dependent synthetase and ligase
AS97_RS08630	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AS97_RS08650	COG0477	Major facilitator Superfamily
AS97_RS08655	COG1022	Amp-dependent synthetase and ligase
AS97_RS08660	COG1309	transcriptional regulator
AS97_RS08675	COG1024	Enoyl-CoA hydratase
AS97_RS08680	COG1024	Enoyl-CoA hydratase
AS97_RS08685	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AS97_RS08695	COG0583	DNA-binding transcription factor activity
AS97_RS08715	COG1140	nitrate reductase beta subunit
AS97_RS08755	COG2814	Major facilitator Superfamily
AS97_RS08760	COG1012	belongs to the aldehyde dehydrogenase family
AS97_RS08770	COG2814	Major facilitator Superfamily
AS97_RS08815	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS08825	COG0667	Aldo Keto reductase
AS97_RS08865	COG4948	Mandelate Racemase Muconate Lactonizing
AS97_RS08875	COG2271	Major facilitator Superfamily
AS97_RS08880	COG2186	Transcriptional regulator
AS97_RS08890	COG1301	dicarboxylic acid transport
AS97_RS08895	COG2828	Protein conserved in bacteria
AS97_RS08940	COG1063	alcohol dehydrogenase
AS97_RS08945	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS08960	COG1175	transmembrane transport
AS97_RS08965	COG0395	ABC-type sugar transport system, permease component
AS97_RS08970	COG4948	Mandelate Racemase Muconate Lactonizing
AS97_RS08985	COG2186	Transcriptional regulator
AS97_RS09005	COG0038	chloride channel
AS97_RS09010	COG2770	Histidine kinase
AS97_RS09010	COG2208	phosphoserine phosphatase activity
AS97_RS09045	COG4977	sequence-specific DNA binding
AS97_RS09045	COG1917	Cupin 2, conserved barrel domain protein
AS97_RS09085	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AS97_RS09090	COG1024	Enoyl-CoA hydratase
AS97_RS09140	COG1335	isochorismatase
AS97_RS09155	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS09165	COG0583	DNA-binding transcription factor activity
AS97_RS09220	COG1175	transmembrane transport
AS97_RS09230	COG1309	transcriptional regulator
AS97_RS09270	COG0109	protoheme IX farnesyltransferase activity
AS97_RS09285	COG3547	Transposase (IS116 IS110 IS902 family)
AS97_RS09330	COG0477	Major facilitator Superfamily
AS97_RS09370	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AS97_RS09375	COG2860	membrane
AS97_RS09390	COG1960	acyl-CoA dehydrogenase activity
AS97_RS09400	COG1250	3-hydroxyacyl-CoA dehydrogenase
AS97_RS09460	COG3321	synthase
AS97_RS09460	COG0604	alcohol dehydrogenase
AS97_RS09520	COG1024	Enoyl-CoA hydratase
AS97_RS09525	COG1024	Enoyl-CoA hydratase
AS97_RS09545	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AS97_RS09555	COG0165	Argininosuccinate lyase
AS97_RS09590	COG4569	acetaldehyde dehydrogenase (acetylating) activity
AS97_RS09600	COG3321	synthase
AS97_RS09600	COG0604	alcohol dehydrogenase
AS97_RS09605	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AS97_RS09615	COG0475	glutathione-regulated potassium exporter activity
AS97_RS09675	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AS97_RS09680	COG3251	PFAM MbtH domain protein
AS97_RS09705	COG1309	transcriptional regulator
AS97_RS09745	COG1968	undecaprenyl-diphosphatase activity
AS97_RS09750	COG0438	transferase activity, transferring glycosyl groups
AS97_RS09755	COG0586	Pfam SNARE associated Golgi protein
AS97_RS09790	COG1929	Belongs to the glycerate kinase type-1 family
AS97_RS09825	COG0667	Aldo Keto reductase
AS97_RS09830	COG1309	transcriptional regulator
AS97_RS09845	COG1116	anion transmembrane transporter activity
AS97_RS09855	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AS97_RS09865	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AS97_RS09870	COG0583	DNA-binding transcription factor activity
AS97_RS09895	COG3876	Protein conserved in bacteria
AS97_RS09910	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AS97_RS09915	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AS97_RS09925	COG1737	Transcriptional regulator
AS97_RS09930	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AS97_RS09945	COG1609	Transcriptional regulator
AS97_RS09950	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS09960	COG0477	Major facilitator Superfamily
AS97_RS09965	COG1053	succinate dehydrogenase
AS97_RS09990	COG0583	DNA-binding transcription factor activity
AS97_RS09995	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AS97_RS10000	COG0531	amino acid
AS97_RS10015	COG2124	cytochrome p450
AS97_RS10020	COG1012	belongs to the aldehyde dehydrogenase family
AS97_RS10085	COG0583	DNA-binding transcription factor activity
AS97_RS10095	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS10130	COG0071	Belongs to the small heat shock protein (HSP20) family
AS97_RS10150	COG0542	response to heat
AS97_RS10155	COG0542	response to heat
AS97_RS10170	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AS97_RS10175	COG0443	Heat shock 70 kDa protein
AS97_RS10240	COG1653	transport
AS97_RS10245	COG1335	isochorismatase
AS97_RS10305	COG0513	Belongs to the DEAD box helicase family
AS97_RS10325	COG0745	RESPONSE REGULATOR receiver
AS97_RS10330	COG0515	serine threonine protein kinase
AS97_RS10355	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS97_RS10360	COG0477	Major facilitator Superfamily
AS97_RS10375	COG4106	trans-aconitate 2-methyltransferase activity
AS97_RS10380	COG1309	transcriptional regulator
AS97_RS10400	COG1024	Enoyl-CoA hydratase
AS97_RS10405	COG1024	Enoyl-CoA hydratase
AS97_RS10410	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AS97_RS10425	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AS97_RS10465	COG0583	DNA-binding transcription factor activity
AS97_RS10470	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AS97_RS10525	COG3547	Transposase (IS116 IS110 IS902 family)
AS97_RS10535	COG0189	ligase activity
AS97_RS10550	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AS97_RS10565	COG2271	Major facilitator Superfamily
AS97_RS10580	COG1802	Transcriptional regulator
AS97_RS10585	COG1024	Enoyl-CoA hydratase
AS97_RS10595	COG1250	3-hydroxyacyl-CoA dehydrogenase
AS97_RS10600	COG0183	Belongs to the thiolase family
AS97_RS10650	COG0649	NAD binding
AS97_RS10735	COG1595	DNA-templated transcription, initiation
AS97_RS10760	COG2362	D-Aminopeptidase
AS97_RS10770	COG0747	negative chemotaxis
AS97_RS10775	COG0601	transmembrane transport
AS97_RS10780	COG0444	Belongs to the ABC transporter superfamily
AS97_RS10800	COG4948	Mandelate Racemase Muconate Lactonizing
AS97_RS10810	COG1012	belongs to the aldehyde dehydrogenase family
AS97_RS10815	COG1012	belongs to the aldehyde dehydrogenase family
AS97_RS10820	COG1012	belongs to the aldehyde dehydrogenase family
AS97_RS10880	COG4104	PAAR repeat-containing protein
AS97_RS10880	COG3209	COG3209 Rhs family protein
AS97_RS10930	COG0583	DNA-binding transcription factor activity
AS97_RS10935	COG1024	Enoyl-CoA hydratase
AS97_RS10940	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AS97_RS10945	COG0477	Major facilitator Superfamily
AS97_RS11015	COG0673	inositol 2-dehydrogenase activity
AS97_RS11025	COG3903	Transcriptional regulator
AS97_RS11025	COG3629	intracellular signal transduction
AS97_RS11030	COG1132	(ABC) transporter
AS97_RS11035	COG1132	(ABC) transporter
AS97_RS11040	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS97_RS11060	COG1132	(ABC) transporter
AS97_RS11095	COG0402	S-adenosylhomocysteine deaminase activity
AS97_RS11105	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AS97_RS11110	COG0351	phosphomethylpyrimidine kinase
AS97_RS11120	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AS97_RS11170	COG3629	intracellular signal transduction
AS97_RS11170	COG3903	Transcriptional regulator
AS97_RS11210	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
AS97_RS11215	COG2222	sugar isomerase
AS97_RS11230	COG0191	fructose-bisphosphate aldolase activity
AS97_RS11245	COG2801	Transposase and inactivated derivatives
AS97_RS11275	COG1725	Transcriptional regulator
AS97_RS11280	COG1131	(ABC) transporter
AS97_RS11400	COG1063	alcohol dehydrogenase
AS97_RS11440	COG2172	sigma factor antagonist activity
AS97_RS11440	COG2208	phosphoserine phosphatase activity
AS97_RS11440	COG1366	Belongs to the anti-sigma-factor antagonist family
AS97_RS11455	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AS97_RS11460	COG0477	Major facilitator Superfamily
AS97_RS11485	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AS97_RS11510	COG1522	sequence-specific DNA binding
AS97_RS11550	COG0154	amidase activity
AS97_RS11555	COG1609	Transcriptional regulator
AS97_RS11580	COG1920	GTP binding
AS97_RS11585	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AS97_RS11590	COG2814	Major facilitator Superfamily
AS97_RS11635	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS11670	COG3959	Transketolase, thiamine diphosphate binding domain
AS97_RS11675	COG3958	Transketolase
AS97_RS11680	COG2267	carboxylic ester hydrolase activity
AS97_RS11685	COG1228	amidohydrolase
AS97_RS11710	COG4175	Glycine betaine
AS97_RS11710	COG0517	IMP dehydrogenase activity
AS97_RS11715	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AS97_RS11740	COG0805	protein transport
AS97_RS11745	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AS97_RS11765	COG2378	regulation of single-species biofilm formation
AS97_RS11775	COG0545	Peptidyl-prolyl cis-trans isomerase
AS97_RS11780	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
AS97_RS11790	COG1609	Transcriptional regulator
AS97_RS11795	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
AS97_RS11800	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
AS97_RS11810	COG4122	O-methyltransferase activity
AS97_RS11815	COG1222	aaa ATPase
AS97_RS11835	COG0517	IMP dehydrogenase activity
AS97_RS11835	COG1994	Peptidase M50
AS97_RS11845	COG2197	response regulator
AS97_RS11860	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AS97_RS11865	COG0646	methionine synthase
AS97_RS11865	COG1410	methionine synthase
AS97_RS11870	COG1414	Transcriptional regulator
AS97_RS11875	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AS97_RS11880	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AS97_RS11885	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AS97_RS11895	COG2186	Transcriptional regulator
AS97_RS11910	COG4211	Belongs to the binding-protein-dependent transport system permease family
AS97_RS11915	COG1129	ABC transporter
AS97_RS11925	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS11930	COG4948	Mandelate Racemase Muconate Lactonizing
AS97_RS11940	COG0215	cysteine-tRNA ligase activity
AS97_RS11960	COG0598	Magnesium transport protein CorA
AS97_RS11970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS97_RS11975	COG0667	Aldo Keto reductase
AS97_RS12000	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AS97_RS12015	COG5520	Belongs to the glycosyl hydrolase 30 family
AS97_RS12020	COG3507	Belongs to the glycosyl hydrolase 43 family
AS97_RS12040	COG1017	nitric oxide dioxygenase activity
AS97_RS12040	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AS97_RS12060	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AS97_RS12065	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AS97_RS12070	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AS97_RS12100	COG4221	oxidoreductase activity
AS97_RS12120	COG0297	glycogen (starch) synthase activity
AS97_RS12140	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AS97_RS12145	COG2080	2 iron, 2 sulfur cluster binding
AS97_RS12150	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AS97_RS12155	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AS97_RS12170	COG0702	epimerase
AS97_RS12190	COG0438	transferase activity, transferring glycosyl groups
AS97_RS12225	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AS97_RS12230	COG2149	membrane
AS97_RS12250	COG1733	regulation of RNA biosynthetic process
AS97_RS12270	COG0318	PFAM AMP-dependent synthetase and ligase
AS97_RS12325	COG0675	Transposase, IS605 OrfB family
AS97_RS12350	COG2851	Citrate transporter
AS97_RS12355	COG0243	molybdopterin cofactor binding
AS97_RS12360	COG1309	transcriptional regulator
AS97_RS12365	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AS97_RS12370	COG2188	Transcriptional regulator
AS97_RS12400	COG2755	lipolytic protein G-D-S-L family
AS97_RS12415	COG1834	amidinotransferase
AS97_RS12420	COG1725	Transcriptional regulator
AS97_RS12430	COG2226	methyltransferase
AS97_RS12435	COG2226	methyltransferase
AS97_RS12440	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AS97_RS12440	COG0596	Alpha beta hydrolase
AS97_RS12440	COG2226	methyltransferase
AS97_RS12445	COG2814	Major facilitator Superfamily
AS97_RS12460	COG4585	Histidine kinase
AS97_RS12465	COG2409	Drug exporters of the RND superfamily
AS97_RS12500	COG1250	3-hydroxyacyl-CoA dehydrogenase
AS97_RS12545	COG0019	diaminopimelate decarboxylase activity
AS97_RS12585	COG1846	Transcriptional regulator
AS97_RS12590	COG1764	response to oxidative stress
AS97_RS12600	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AS97_RS12605	COG0587	DNA-directed DNA polymerase activity
AS97_RS12610	COG3467	pyridoxamine 5'-phosphate
AS97_RS12625	COG0330	HflC and HflK could
AS97_RS12635	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS97_RS12640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS97_RS12645	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AS97_RS12670	COG1799	cell septum assembly
AS97_RS12675	COG1960	acyl-CoA dehydrogenase activity
AS97_RS12680	COG0477	Major facilitator Superfamily
AS97_RS12690	COG0671	phosphoesterase, PA-phosphatase related
AS97_RS12740	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AS97_RS12755	COG0438	transferase activity, transferring glycosyl groups
AS97_RS12770	COG1160	GTP binding
AS97_RS12780	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AS97_RS12795	COG1187	pseudouridine synthase activity
AS97_RS12800	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AS97_RS12805	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AS97_RS12820	COG0686	Belongs to the AlaDH PNT family
AS97_RS12825	COG3903	Transcriptional regulator
AS97_RS12825	COG3629	intracellular signal transduction
AS97_RS12830	COG0494	nUDIX hydrolase
AS97_RS12835	COG0504	CTP synthase activity
AS97_RS12840	COG3387	PFAM Glycoside hydrolase 15-related
AS97_RS12855	COG0297	glycogen (starch) synthase activity
AS97_RS12860	COG0497	DNA recombination
AS97_RS12865	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AS97_RS12885	COG1120	ATPase activity
AS97_RS12890	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS97_RS12895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS97_RS12900	COG0647	UMP catabolic process
AS97_RS12935	COG2094	Belongs to the DNA glycosylase MPG family
AS97_RS12945	COG2732	(Barnase) inhibitor
AS97_RS12950	COG1881	PFAM PEBP family protein
AS97_RS12970	COG1119	ATPase activity
AS97_RS12985	COG2197	response regulator
AS97_RS13000	COG1131	(ABC) transporter
AS97_RS13000	COG0842	Transport permease protein
AS97_RS13000	COG1716	ATPase activity
AS97_RS13010	COG0560	Phosphoserine phosphatase
AS97_RS13010	COG3830	Belongs to the UPF0237 family
AS97_RS13025	COG2807	transmembrane transport
AS97_RS13030	COG2186	Transcriptional regulator
AS97_RS13040	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AS97_RS13045	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS13105	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AS97_RS13125	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AS97_RS13130	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AS97_RS13165	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AS97_RS13180	COG3387	PFAM Glycoside hydrolase 15-related
AS97_RS13225	COG2205	protein histidine kinase activity
AS97_RS13225	COG3437	response regulator, receiver
AS97_RS13225	COG3850	Histidine kinase
AS97_RS13225	COG4999	Histidine kinase
AS97_RS13235	COG1024	Enoyl-CoA hydratase
AS97_RS13245	COG0488	(ABC) transporter
AS97_RS13260	COG0235	Class ii aldolase
AS97_RS13275	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AS97_RS13280	COG1492	cobalamin metabolic process
AS97_RS13295	COG1797	cobyrinic acid a,c-diamide synthase activity
AS97_RS13335	COG0456	acetyltransferase
AS97_RS13345	COG1917	Cupin 2, conserved barrel domain protein
AS97_RS13350	COG5285	phytanoyl-CoA dioxygenase
AS97_RS13355	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AS97_RS13365	COG1414	Transcriptional regulator
AS97_RS13375	COG4585	Histidine kinase
AS97_RS13385	COG0667	Aldo Keto reductase
AS97_RS13395	COG0726	polysaccharide deacetylase
AS97_RS13415	COG0395	ABC-type sugar transport system, permease component
AS97_RS13430	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AS97_RS13435	COG1802	Transcriptional regulator
AS97_RS13445	COG2223	nitrite transmembrane transporter activity
AS97_RS13455	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AS97_RS13460	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AS97_RS13465	COG1335	isochorismatase
AS97_RS13470	COG0477	Major facilitator Superfamily
AS97_RS13525	COG2171	N-acyltransferase activity
AS97_RS13535	COG2076	Multidrug Resistance protein
AS97_RS13545	COG0822	iron-sulfur transferase activity
AS97_RS13550	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AS97_RS13555	COG0396	ATPase activity
AS97_RS13565	COG0719	Fe-S assembly protein
AS97_RS13590	COG1612	heme a metabolic process
AS97_RS13605	COG0109	protoheme IX farnesyltransferase activity
AS97_RS13610	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AS97_RS13615	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AS97_RS13630	COG0363	glucosamine-6-phosphate deaminase activity
AS97_RS13635	COG0166	Belongs to the GPI family
AS97_RS13650	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AS97_RS13655	COG0149	triose-phosphate isomerase activity
AS97_RS13660	COG0126	phosphoglycerate kinase activity
AS97_RS13665	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AS97_RS13680	COG1481	regulation of sporulation
AS97_RS13690	COG1660	Displays ATPase and GTPase activities
AS97_RS13695	COG0322	excinuclease ABC activity
AS97_RS13715	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AS97_RS13730	COG0477	Major facilitator Superfamily
AS97_RS13750	COG0556	nucleotide-excision repair
AS97_RS13755	COG0584	glycerophosphoryl diester phosphodiesterase
AS97_RS13760	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AS97_RS13815	COG0237	dephospho-CoA kinase activity
AS97_RS13840	COG1643	Atp-dependent helicase
AS97_RS13885	COG2050	protein possibly involved in aromatic compounds catabolism
AS97_RS13910	COG0411	ABC transporter
AS97_RS13945	COG0737	Belongs to the 5'-nucleotidase family
AS97_RS13955	COG0076	glutamate decarboxylase activity
AS97_RS13975	COG1140	nitrate reductase beta subunit
AS97_RS13995	COG0287	Prephenate dehydrogenase
AS97_RS13995	COG1605	Chorismate mutase
AS97_RS14015	COG3467	pyridoxamine 5'-phosphate
AS97_RS14035	COG0067	glutamate synthase
AS97_RS14035	COG0069	glutamate synthase activity
AS97_RS14035	COG0070	glutamate synthase
AS97_RS14045	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AS97_RS14055	COG0159	tryptophan synthase activity
AS97_RS14060	COG0133	tryptophan synthase activity
AS97_RS14065	COG0134	indole-3-glycerol-phosphate synthase activity
AS97_RS14085	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AS97_RS14090	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AS97_RS14110	COG4221	oxidoreductase activity
AS97_RS14140	COG1902	pentaerythritol trinitrate reductase activity
AS97_RS14145	COG0789	Transcriptional regulator
AS97_RS14160	COG0107	imidazoleglycerol-phosphate synthase activity
AS97_RS14165	COG0251	oxidation-reduction process
AS97_RS14170	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AS97_RS14175	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AS97_RS14190	COG0131	Imidazoleglycerol-phosphate dehydratase
AS97_RS14195	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AS97_RS14200	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AS97_RS14210	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AS97_RS14215	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AS97_RS14245	COG0587	DNA-directed DNA polymerase activity
AS97_RS14295	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AS97_RS14305	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AS97_RS14320	COG1799	cell septum assembly
AS97_RS14330	COG1496	oxidoreductase activity
AS97_RS14335	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AS97_RS14340	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AS97_RS14345	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AS97_RS14355	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AS97_RS14360	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AS97_RS14370	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AS97_RS14375	COG0768	penicillin binding
AS97_RS14385	COG0275	rRNA processing
AS97_RS14395	COG0714	Associated with various cellular activities
AS97_RS14425	COG1129	ABC transporter
AS97_RS14435	COG1309	transcriptional regulator
AS97_RS14440	COG1233	COG1233 Phytoene dehydrogenase and related
AS97_RS14455	COG0352	thiamine-phosphate diphosphorylase activity
AS97_RS14470	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AS97_RS14470	COG2022	thiamine diphosphate biosynthetic process
AS97_RS14480	COG2022	thiamine diphosphate biosynthetic process
AS97_RS14490	COG2815	serine threonine protein kinase
AS97_RS14490	COG0515	serine threonine protein kinase
AS97_RS14500	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AS97_RS14510	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AS97_RS14515	COG2193	ferroxidase activity
AS97_RS14525	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AS97_RS14545	COG0205	6-phosphofructokinase activity
AS97_RS14550	COG2197	response regulator
AS97_RS14580	COG1940	carbohydrate kinase activity
AS97_RS14590	COG0003	Pfam Anion-transporting ATPase
AS97_RS14650	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AS97_RS14655	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AS97_RS14660	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AS97_RS14665	COG0723	plastoquinol--plastocyanin reductase activity
AS97_RS14670	COG2010	Cytochrome c
AS97_RS14675	COG1845	cytochrome c oxidase, subunit III
AS97_RS14685	COG1376	ErfK ybiS ycfS ynhG family protein
AS97_RS14695	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AS97_RS14700	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AS97_RS14710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AS97_RS14730	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AS97_RS14735	COG2197	response regulator
AS97_RS14740	COG4585	Histidine kinase
AS97_RS14775	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AS97_RS14780	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AS97_RS14785	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AS97_RS14790	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AS97_RS14795	COG0508	dehydrogenase complex catalyzes the overall conversion of
AS97_RS14805	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AS97_RS14815	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS14845	COG0640	Transcriptional regulator
AS97_RS14855	COG0321	lipoyl(octanoyl) transferase activity
AS97_RS14860	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AS97_RS14895	COG1280	lysine exporter protein (LysE YggA)
AS97_RS14905	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AS97_RS14935	COG0477	Major facilitator Superfamily
AS97_RS14955	COG0745	RESPONSE REGULATOR receiver
AS97_RS14980	COG2197	response regulator
AS97_RS15025	COG3833	ABC-type maltose transport systems, permease component
AS97_RS15035	COG2182	Extracellular solute-binding protein
AS97_RS15040	COG0366	Alpha amylase catalytic
AS97_RS15045	COG1609	Transcriptional regulator
AS97_RS15060	COG0561	phosphatase activity
AS97_RS15065	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AS97_RS15075	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
AS97_RS15105	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AS97_RS15110	COG0174	glutamine synthetase
AS97_RS15115	COG2132	Multicopper oxidase
AS97_RS15120	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AS97_RS15120	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AS97_RS15125	COG2814	Major facilitator Superfamily
AS97_RS15135	COG1309	transcriptional regulator
AS97_RS15140	COG0477	Major facilitator Superfamily
AS97_RS15145	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AS97_RS15165	COG1994	Peptidase M50
AS97_RS15180	COG0395	ABC-type sugar transport system, permease component
AS97_RS15185	COG1175	transmembrane transport
AS97_RS15230	COG2822	iron ion transport
AS97_RS15235	COG2837	iron assimilation
AS97_RS15240	COG0672	)-iron permease
AS97_RS15265	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AS97_RS15270	COG2814	Major facilitator Superfamily
AS97_RS15280	COG3540	Alkaline phosphatase
AS97_RS15285	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS15330	COG1414	Transcriptional regulator
AS97_RS15340	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AS97_RS15345	COG0477	Major facilitator Superfamily
AS97_RS15365	COG3022	response to hydroperoxide
AS97_RS15370	COG0800	Aldolase
AS97_RS15385	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AS97_RS15390	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AS97_RS15410	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS15415	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AS97_RS15420	COG2030	dehydratase
AS97_RS15425	COG4585	Histidine kinase
AS97_RS15430	COG2197	response regulator
AS97_RS15440	COG0860	N-Acetylmuramoyl-L-alanine amidase
AS97_RS15450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS97_RS15470	COG0438	transferase activity, transferring glycosyl groups
AS97_RS15475	COG1309	transcriptional regulator
AS97_RS15480	COG2197	response regulator
AS97_RS15520	COG3845	ABC transporter
AS97_RS15535	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AS97_RS15540	COG0183	Belongs to the thiolase family
AS97_RS15545	COG2124	cytochrome p450
AS97_RS15565	COG2207	Transcriptional regulator
AS97_RS15595	COG0596	Alpha beta hydrolase
AS97_RS15615	COG0745	RESPONSE REGULATOR receiver
AS97_RS15620	COG5002	protein histidine kinase activity
AS97_RS15640	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AS97_RS15740	COG1396	sequence-specific DNA binding
AS97_RS15750	COG0740	serine-type endopeptidase activity
AS97_RS15755	COG0740	serine-type endopeptidase activity
AS97_RS15775	COG1959	2 iron, 2 sulfur cluster binding
AS97_RS15785	COG1073	alpha beta
AS97_RS15810	COG2197	response regulator
AS97_RS15815	COG4585	Histidine kinase
AS97_RS15850	COG4977	sequence-specific DNA binding
AS97_RS15890	COG1358	cellular component organization or biogenesis
AS97_RS15935	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AS97_RS15945	COG0477	Major facilitator Superfamily
AS97_RS15950	COG1309	transcriptional regulator
AS97_RS15965	COG4585	Histidine kinase
AS97_RS15970	COG2197	response regulator
AS97_RS15980	COG0667	Aldo Keto reductase
AS97_RS15985	COG0789	Transcriptional regulator
AS97_RS16010	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AS97_RS16015	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AS97_RS16020	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AS97_RS16045	COG1309	transcriptional regulator
AS97_RS16090	COG4214	carbohydrate transport
AS97_RS16165	COG2130	NADP-dependent
AS97_RS16180	COG3386	PFAM SMP-30 Gluconolaconase
AS97_RS16185	COG1414	Transcriptional regulator
AS97_RS16200	COG0588	phosphoglycerate mutase activity
AS97_RS16205	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS97_RS16210	COG2130	NADP-dependent
AS97_RS16255	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AS97_RS16255	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AS97_RS16265	COG2197	response regulator
AS97_RS16270	COG3851	Histidine kinase
AS97_RS16325	COG1070	Carbohydrate kinase
AS97_RS16335	COG0358	DNA primase activity
AS97_RS16345	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AS97_RS16355	COG0243	molybdopterin cofactor binding
AS97_RS16360	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AS97_RS16365	COG2949	membrane
AS97_RS16395	COG0745	RESPONSE REGULATOR receiver
AS97_RS16400	COG5002	protein histidine kinase activity
AS97_RS16425	COG2124	cytochrome p450
AS97_RS16435	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AS97_RS16440	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AS97_RS16440	COG2146	nitrite reductase [NAD(P)H] activity
AS97_RS16445	COG2146	nitrite reductase [NAD(P)H] activity
AS97_RS16445	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AS97_RS16465	COG1609	Transcriptional regulator
AS97_RS16475	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS16480	COG2890	protein-(glutamine-N5) methyltransferase activity
AS97_RS16485	COG1846	Transcriptional regulator
AS97_RS16490	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AS97_RS16495	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AS97_RS16500	COG0183	Belongs to the thiolase family
AS97_RS16505	COG3485	protocatechuate 3,4-dioxygenase
AS97_RS16510	COG3485	protocatechuate 3,4-dioxygenase
AS97_RS16515	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AS97_RS16520	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AS97_RS16525	COG2182	Extracellular solute-binding protein
AS97_RS16535	COG0395	ABC-type sugar transport system, permease component
AS97_RS16555	COG4585	Histidine kinase
AS97_RS16560	COG2197	response regulator
AS97_RS16590	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AS97_RS16590	COG0574	Belongs to the PEP-utilizing enzyme family
AS97_RS16615	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AS97_RS16630	COG0477	Major facilitator Superfamily
AS97_RS16635	COG2197	response regulator
AS97_RS16655	COG0423	glycine-tRNA ligase activity
AS97_RS16665	COG1121	(ABC) transporter
AS97_RS16670	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AS97_RS16725	COG0667	Aldo Keto reductase
AS97_RS16730	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AS97_RS16735	COG1381	Involved in DNA repair and RecF pathway recombination
AS97_RS16760	COG1846	Transcriptional regulator
AS97_RS16775	COG2315	Protein conserved in bacteria
AS97_RS16785	COG0454	-acetyltransferase
AS97_RS16785	COG0456	acetyltransferase
AS97_RS16810	COG2197	response regulator
AS97_RS16815	COG4585	Histidine kinase
AS97_RS16820	COG2409	Drug exporters of the RND superfamily
AS97_RS16830	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AS97_RS16845	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AS97_RS16865	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AS97_RS16875	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AS97_RS16880	COG1234	tRNA 3'-trailer cleavage
AS97_RS16885	COG0537	adenosine 5'-monophosphoramidase activity
AS97_RS16905	COG0484	heat shock protein binding
AS97_RS16910	COG1420	regulation of RNA biosynthetic process
AS97_RS16935	COG1022	Amp-dependent synthetase and ligase
AS97_RS16940	COG0481	GTPase activity
AS97_RS16945	COG0268	Binds directly to 16S ribosomal RNA
AS97_RS17005	COG1555	photosystem II stabilization
AS97_RS17010	COG1307	EDD domain protein, DegV family
AS97_RS17020	COG0495	leucyl-tRNA aminoacylation
AS97_RS17050	COG0588	phosphoglycerate mutase activity
AS97_RS17055	COG0799	negative regulation of ribosome biogenesis
AS97_RS17065	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AS97_RS17080	COG0501	Belongs to the peptidase M48B family
AS97_RS17095	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AS97_RS17105	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AS97_RS17115	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AS97_RS17120	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AS97_RS17125	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AS97_RS17130	COG1530	ribonuclease E activity
AS97_RS17150	COG0772	Belongs to the SEDS family
AS97_RS17155	COG0768	penicillin binding
AS97_RS17170	COG1077	Cell shape determining protein MreB Mrl
AS97_RS17175	COG0105	UTP biosynthetic process
AS97_RS17185	COG0285	dihydrofolate synthase activity
AS97_RS17190	COG0768	penicillin binding
AS97_RS17195	COG0525	valine-tRNA ligase activity
AS97_RS17215	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AS97_RS17220	COG0740	serine-type endopeptidase activity
AS97_RS17225	COG0740	serine-type endopeptidase activity
AS97_RS17230	COG0544	peptidyl-prolyl cis-trans isomerase activity
AS97_RS17250	COG3594	Acyltransferase
AS97_RS17260	COG1136	(ABC) transporter
AS97_RS17270	COG4552	Acetyltransferase involved in intracellular survival and related
AS97_RS17285	COG1113	amino acid transport
AS97_RS17290	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AS97_RS17295	COG1113	amino acid transport
AS97_RS17305	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AS97_RS17365	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AS97_RS17365	COG3291	Pkd domain containing protein
AS97_RS17375	COG0668	transmembrane transport
AS97_RS17385	COG1846	Transcriptional regulator
AS97_RS17385	COG1940	carbohydrate kinase activity
AS97_RS17395	COG1175	transmembrane transport
AS97_RS17405	COG1486	melibiose metabolic process
AS97_RS17420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AS97_RS17485	COG0629	single-stranded DNA binding
AS97_RS17510	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AS97_RS17550	COG3251	PFAM MbtH domain protein
AS97_RS17555	COG0142	geranyltranstransferase activity
AS97_RS17560	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AS97_RS17565	COG1993	acr, cog1993
AS97_RS17570	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AS97_RS17575	COG0583	DNA-binding transcription factor activity
AS97_RS17595	COG0318	PFAM AMP-dependent synthetase and ligase
AS97_RS17605	COG1131	(ABC) transporter
AS97_RS17645	COG0604	alcohol dehydrogenase
AS97_RS17645	COG3321	synthase
AS97_RS17650	COG0604	alcohol dehydrogenase
AS97_RS17650	COG3321	synthase
AS97_RS17660	COG0604	alcohol dehydrogenase
AS97_RS17660	COG3321	synthase
AS97_RS17680	COG3321	synthase
AS97_RS17680	COG0604	alcohol dehydrogenase
AS97_RS17710	COG3402	PFAM membrane-flanked domain
AS97_RS17720	COG4585	Histidine kinase
AS97_RS17725	COG2197	response regulator
AS97_RS17760	COG3962	Belongs to the TPP enzyme family
AS97_RS17765	COG3718	enzyme involved in inositol metabolism
AS97_RS17775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AS97_RS17790	COG1312	Catalyzes the dehydration of D-mannonate
AS97_RS17795	COG0673	inositol 2-dehydrogenase activity
AS97_RS17805	COG2409	Drug exporters of the RND superfamily
AS97_RS17830	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AS97_RS17840	COG1129	ABC transporter
AS97_RS17845	COG1879	ABC-type sugar transport system periplasmic component
AS97_RS17850	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AS97_RS17855	COG1869	D-ribose catabolic process
AS97_RS17865	COG1595	DNA-templated transcription, initiation
AS97_RS17920	COG0673	inositol 2-dehydrogenase activity
AS97_RS17935	COG0395	ABC-type sugar transport system, permease component
AS97_RS17940	COG1175	transmembrane transport
AS97_RS17965	COG1609	Transcriptional regulator
AS97_RS17985	COG1846	Transcriptional regulator
AS97_RS17985	COG0456	acetyltransferase
AS97_RS18010	COG1472	Belongs to the glycosyl hydrolase 3 family
AS97_RS18035	COG2197	response regulator
AS97_RS18040	COG4585	Histidine kinase
AS97_RS18075	COG1278	Cold shock
AS97_RS18080	COG0513	Belongs to the DEAD box helicase family
AS97_RS18090	COG1946	Acyl-CoA thioesterase
AS97_RS18100	COG1309	transcriptional regulator
AS97_RS18105	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AS97_RS18125	COG1960	acyl-CoA dehydrogenase activity
AS97_RS18145	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AS97_RS18150	COG0589	response to stress
AS97_RS18160	COG4977	sequence-specific DNA binding
AS97_RS18165	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AS97_RS18190	COG0789	Transcriptional regulator
AS97_RS18220	COG4733	cellulase activity
AS97_RS18220	COG5297	Belongs to the glycosyl hydrolase family 6
AS97_RS18230	COG5297	Belongs to the glycosyl hydrolase family 6
AS97_RS18260	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AS97_RS18265	COG3979	chitinase
AS97_RS18375	COG4585	Histidine kinase
AS97_RS18380	COG2197	response regulator
AS97_RS18400	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS97_RS18420	COG3473	Maleate cis-trans isomerase
AS97_RS18435	COG0154	amidase activity
AS97_RS18445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AS97_RS18450	COG0765	amino acid transport
AS97_RS18455	COG0765	amino acid transport
AS97_RS18460	COG1126	abc transporter atp-binding protein
AS97_RS18480	COG2267	carboxylic ester hydrolase activity
AS97_RS18495	COG4770	biotin carboxylase activity
AS97_RS18510	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS18515	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AS97_RS18525	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AS97_RS18530	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AS97_RS18555	COG0300	oxidoreductase activity
AS97_RS18580	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AS97_RS18585	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AS97_RS18590	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AS97_RS18600	COG0477	Major facilitator Superfamily
AS97_RS18605	COG1063	alcohol dehydrogenase
AS97_RS18620	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AS97_RS18625	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AS97_RS18660	COG3397	chitin binding
AS97_RS18680	COG3548	integral membrane protein
AS97_RS18705	COG2186	Transcriptional regulator
AS97_RS18750	COG0673	inositol 2-dehydrogenase activity
AS97_RS18755	COG4702	Belongs to the UPF0303 family
AS97_RS18765	COG0706	membrane insertase activity
AS97_RS18775	COG3764	Sortase (surface protein transpeptidase)
AS97_RS18780	COG2733	membrane
AS97_RS18810	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AS97_RS18815	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AS97_RS18835	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AS97_RS18845	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AS97_RS18850	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AS97_RS18855	COG1263	PTS System
AS97_RS18865	COG2274	protein secretion by the type I secretion system
AS97_RS18875	COG1234	tRNA 3'-trailer cleavage
AS97_RS18895	COG1113	amino acid transport
AS97_RS18905	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AS97_RS18915	COG1335	isochorismatase
AS97_RS18955	COG1064	alcohol dehydrogenase
AS97_RS18980	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AS97_RS18985	COG0277	FAD linked oxidase domain protein
AS97_RS18995	COG3185	4-Hydroxyphenylpyruvate dioxygenase
AS97_RS19035	COG3654	unkown
AS97_RS19050	COG2855	membrane
AS97_RS19060	COG0583	DNA-binding transcription factor activity
AS97_RS19075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS97_RS19080	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AS97_RS19095	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AS97_RS19100	COG0395	ABC-type sugar transport system, permease component
AS97_RS19105	COG1175	transmembrane transport
AS97_RS19125	COG1678	Uncharacterized ACR, COG1678
AS97_RS19130	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AS97_RS19135	COG0776	regulation of translation
AS97_RS19145	COG1278	Cold shock
AS97_RS19150	COG3973	AAA domain
AS97_RS19175	COG2223	nitrite transmembrane transporter activity
AS97_RS19190	COG0583	DNA-binding transcription factor activity
AS97_RS19205	COG0583	DNA-binding transcription factor activity
AS97_RS19220	COG0395	ABC-type sugar transport system, permease component
AS97_RS19225	COG1501	Belongs to the glycosyl hydrolase 31 family
AS97_RS19280	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AS97_RS19290	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AS97_RS19295	COG0793	Belongs to the peptidase S41A family
AS97_RS19305	COG2884	Cell division ATP-binding protein ftsE
AS97_RS19320	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AS97_RS19325	COG0515	serine threonine protein kinase
AS97_RS19330	COG0515	serine threonine protein kinase
AS97_RS19345	COG1653	transport
AS97_RS19350	COG1175	transmembrane transport
AS97_RS19355	COG0395	ABC-type sugar transport system, permease component
AS97_RS19395	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AS97_RS19395	COG0463	Glycosyl transferase, family 2
AS97_RS19400	COG0438	transferase activity, transferring glycosyl groups
AS97_RS19430	COG0463	Glycosyl transferase, family 2
AS97_RS19430	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AS97_RS19435	COG2902	Dehydrogenase
AS97_RS19440	COG0693	protein deglycase activity
AS97_RS19445	COG0546	phosphoglycolate phosphatase activity
AS97_RS19460	COG0653	protein targeting
AS97_RS19470	COG3214	Protein conserved in bacteria
AS97_RS19475	COG2197	response regulator
AS97_RS19480	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AS97_RS19490	COG0823	Involved in the tonB-independent uptake of proteins
AS97_RS19495	COG5000	phosphorelay sensor kinase activity
AS97_RS19495	COG5002	protein histidine kinase activity
AS97_RS19500	COG0745	RESPONSE REGULATOR receiver
AS97_RS19505	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AS97_RS19535	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AS97_RS19540	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AS97_RS19540	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AS97_RS19540	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AS97_RS19550	COG1482	cell wall glycoprotein biosynthetic process
AS97_RS19560	COG2835	tetraacyldisaccharide 4'-kinase activity
AS97_RS19565	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AS97_RS19570	COG1620	l-lactate permease
AS97_RS19605	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AS97_RS19610	COG0778	Nitroreductase
AS97_RS19610	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
AS97_RS19635	COG1316	TRANSCRIPTIONal
AS97_RS19640	COG1316	TRANSCRIPTIONal
AS97_RS19655	COG1316	TRANSCRIPTIONal
AS97_RS19660	COG1607	acyl-coa hydrolase
AS97_RS19665	COG1316	TRANSCRIPTIONal
AS97_RS19705	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AS97_RS19735	COG2205	protein histidine kinase activity
AS97_RS19740	COG0745	RESPONSE REGULATOR receiver
AS97_RS19745	COG3104	oligopeptide transport
AS97_RS19775	COG1366	Belongs to the anti-sigma-factor antagonist family
AS97_RS19780	COG1191	sigma factor activity
AS97_RS19785	COG1228	amidohydrolase
AS97_RS19800	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AS97_RS19835	COG2986	histidine ammonia-lyase
AS97_RS19845	COG1174	glycine betaine transport
AS97_RS19860	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AS97_RS19865	COG0318	PFAM AMP-dependent synthetase and ligase
AS97_RS19890	COG2755	lipolytic protein G-D-S-L family
AS97_RS19895	COG0183	Belongs to the thiolase family
AS97_RS19925	COG0577	efflux transmembrane transporter activity
AS97_RS19925	COG1136	(ABC) transporter
AS97_RS19930	COG0577	efflux transmembrane transporter activity
AS97_RS19935	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AS97_RS19940	COG1252	NADH dehydrogenase
AS97_RS19960	COG0148	phosphopyruvate hydratase activity
AS97_RS19975	COG2124	cytochrome p450
AS97_RS20010	COG3033	Beta-eliminating lyase
AS97_RS20060	COG2986	histidine ammonia-lyase
AS97_RS20070	COG1024	Enoyl-CoA hydratase
AS97_RS20080	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AS97_RS20090	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AS97_RS20100	COG0424	maF-like protein
AS97_RS20110	COG4770	biotin carboxylase activity
AS97_RS20145	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AS97_RS20165	COG1012	belongs to the aldehyde dehydrogenase family
AS97_RS20180	COG1595	DNA-templated transcription, initiation
AS97_RS20185	COG0745	RESPONSE REGULATOR receiver
AS97_RS20190	COG2205	protein histidine kinase activity
AS97_RS20215	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AS97_RS20225	COG2814	Major facilitator Superfamily
AS97_RS20230	COG0583	DNA-binding transcription factor activity
AS97_RS20255	COG1079	Belongs to the binding-protein-dependent transport system permease family
AS97_RS20260	COG4603	Belongs to the binding-protein-dependent transport system permease family
AS97_RS20265	COG3845	ABC transporter
AS97_RS20270	COG1744	ABC transporter substrate-binding protein PnrA-like
AS97_RS20300	COG1473	amidohydrolase
AS97_RS20300	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AS97_RS20310	COG2089	acid synthase
AS97_RS20315	COG1083	cytidylyl-transferase
AS97_RS20325	COG1216	Glycosyl transferase, family 2
AS97_RS20335	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AS97_RS20370	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AS97_RS20385	COG1063	alcohol dehydrogenase
AS97_RS20390	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS20400	COG3265	gluconokinase activity
AS97_RS20405	COG2186	Transcriptional regulator
AS97_RS20410	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS20415	COG1309	transcriptional regulator
AS97_RS20440	COG1316	TRANSCRIPTIONal
AS97_RS20445	COG1215	transferase activity, transferring glycosyl groups
AS97_RS20475	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AS97_RS20475	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AS97_RS20490	COG1595	DNA-templated transcription, initiation
AS97_RS20510	COG2009	succinate dehydrogenase
AS97_RS20525	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AS97_RS20535	COG1408	metallophosphoesterase
AS97_RS20540	COG1686	Belongs to the peptidase S11 family
AS97_RS20545	COG1295	ribonuclease BN
AS97_RS20560	COG0180	Tryptophanyl-tRNA synthetase
AS97_RS20570	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AS97_RS20575	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AS97_RS20580	COG0754	glutathionylspermidine amidase activity
AS97_RS20590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS97_RS20595	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AS97_RS20610	COG4176	ABC-type proline glycine betaine transport system permease component
AS97_RS20615	COG0517	IMP dehydrogenase activity
AS97_RS20615	COG4175	Glycine betaine
AS97_RS20625	COG1012	belongs to the aldehyde dehydrogenase family
AS97_RS20650	COG0039	L-malate dehydrogenase activity
AS97_RS20665	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AS97_RS20670	COG0138	bifunctional purine biosynthesis protein purh
AS97_RS20695	COG0045	succinate-CoA ligase (ADP-forming) activity
AS97_RS20710	COG3552	Protein containing von Willebrand factor type A (VWA) domain
AS97_RS20720	COG0714	Associated with various cellular activities
AS97_RS20735	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AS97_RS20745	COG0739	heme binding
AS97_RS20790	COG2197	response regulator
AS97_RS20810	COG0515	serine threonine protein kinase
AS97_RS20835	COG0519	Catalyzes the synthesis of GMP from XMP
AS97_RS20835	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AS97_RS20855	COG1012	belongs to the aldehyde dehydrogenase family
AS97_RS20860	COG2815	serine threonine protein kinase
AS97_RS20860	COG0515	serine threonine protein kinase
AS97_RS20865	COG0515	serine threonine protein kinase
AS97_RS20885	COG2197	response regulator
AS97_RS20890	COG4585	Histidine kinase
AS97_RS20895	COG1366	Belongs to the anti-sigma-factor antagonist family
AS97_RS20940	COG1131	(ABC) transporter
AS97_RS20965	COG0596	Alpha beta hydrolase
AS97_RS20965	COG2945	thiolester hydrolase activity
AS97_RS20975	COG4821	SIS domain
AS97_RS20985	COG0259	pyridoxamine-phosphate oxidase activity
AS97_RS20995	COG1309	transcriptional regulator
AS97_RS21000	COG1024	Enoyl-CoA hydratase
AS97_RS21005	COG0318	PFAM AMP-dependent synthetase and ligase
AS97_RS21020	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AS97_RS21050	COG2442	InterPro IPR007367
AS97_RS21055	COG0247	lactate metabolic process
AS97_RS21055	COG0277	FAD linked oxidase domain protein
AS97_RS21060	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AS97_RS21075	COG0667	Aldo Keto reductase
AS97_RS21095	COG2252	PERMEase
AS97_RS21120	COG2814	Major facilitator Superfamily
AS97_RS21130	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AS97_RS21135	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
AS97_RS21140	COG1278	Cold shock
AS97_RS21155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS97_RS21160	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS97_RS21165	COG1120	ATPase activity
AS97_RS21185	COG1061	Type III restriction enzyme res subunit
AS97_RS21195	COG3973	AAA domain
AS97_RS21205	COG3142	Participates in the control of copper homeostasis
AS97_RS21235	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AS97_RS21240	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AS97_RS21245	COG0459	protein refolding
AS97_RS21250	COG1278	Cold shock
AS97_RS21265	COG0463	Glycosyl transferase, family 2
AS97_RS21275	COG1877	trehalose-phosphatase activity
AS97_RS21275	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AS97_RS21290	COG1940	carbohydrate kinase activity
AS97_RS21300	COG1105	Belongs to the carbohydrate kinase PfkB family
AS97_RS21315	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AS97_RS21320	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AS97_RS21335	COG1309	transcriptional regulator
AS97_RS21340	COG1064	alcohol dehydrogenase
AS97_RS21355	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS97_RS21360	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AS97_RS21395	COG2124	cytochrome p450
AS97_RS21415	COG2124	cytochrome p450
AS97_RS21435	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AS97_RS21450	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS21455	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AS97_RS21485	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AS97_RS21490	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AS97_RS21495	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AS97_RS21510	COG3903	Transcriptional regulator
AS97_RS21510	COG3629	intracellular signal transduction
AS97_RS21545	COG3842	ATPase activity
AS97_RS21555	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AS97_RS21570	COG0215	cysteine-tRNA ligase activity
AS97_RS21575	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AS97_RS21580	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AS97_RS21585	COG1329	Transcriptional regulator
AS97_RS21600	COG5002	protein histidine kinase activity
AS97_RS21615	COG4249	Peptidase C14 caspase catalytic subunit p20
AS97_RS21615	COG2319	Wd-40 repeat
AS97_RS21630	COG1215	transferase activity, transferring glycosyl groups
AS97_RS21635	COG2188	Transcriptional regulator
AS97_RS21645	COG0588	phosphoglycerate mutase activity
AS97_RS21675	COG0438	transferase activity, transferring glycosyl groups
AS97_RS21685	COG0531	amino acid
AS97_RS21695	COG0667	Aldo Keto reductase
AS97_RS21700	COG0406	alpha-ribazole phosphatase activity
AS97_RS21700	COG0494	nUDIX hydrolase
AS97_RS21710	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AS97_RS21715	COG0454	-acetyltransferase
AS97_RS21715	COG0456	acetyltransferase
AS97_RS21720	COG4804	nuclease activity
AS97_RS21725	COG0737	Belongs to the 5'-nucleotidase family
AS97_RS21740	COG1024	Enoyl-CoA hydratase
AS97_RS21745	COG1733	regulation of RNA biosynthetic process
AS97_RS21795	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AS97_RS21815	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AS97_RS21825	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AS97_RS21830	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AS97_RS21850	COG0640	Transcriptional regulator
AS97_RS21855	COG0640	Transcriptional regulator
AS97_RS21860	COG2197	response regulator
AS97_RS21875	COG0649	NAD binding
AS97_RS21890	COG1174	glycine betaine transport
AS97_RS21895	COG1174	glycine betaine transport
AS97_RS21900	COG0517	IMP dehydrogenase activity
AS97_RS21900	COG1125	glycine betaine transport
AS97_RS21910	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AS97_RS21910	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AS97_RS21925	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AS97_RS21930	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AS97_RS21940	COG0302	gtp cyclohydrolase
AS97_RS21955	COG0037	tRNA processing
AS97_RS21965	COG2027	D-alanyl-D-alanine carboxypeptidase
AS97_RS21970	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AS97_RS21980	COG0586	Pfam SNARE associated Golgi protein
AS97_RS21985	COG0789	Transcriptional regulator
AS97_RS21995	COG0076	glutamate decarboxylase activity
AS97_RS22020	COG2318	DinB family
AS97_RS22025	COG1012	belongs to the aldehyde dehydrogenase family
AS97_RS22050	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AS97_RS22050	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AS97_RS22055	COG1077	Cell shape determining protein MreB Mrl
AS97_RS22070	COG1595	DNA-templated transcription, initiation
AS97_RS22080	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AS97_RS22085	COG2197	response regulator
AS97_RS22135	COG0671	phosphoesterase, PA-phosphatase related
AS97_RS22140	COG2197	response regulator
AS97_RS22145	COG4585	Histidine kinase
AS97_RS22165	COG1191	sigma factor activity
AS97_RS22170	COG0640	Transcriptional regulator
AS97_RS22180	COG2197	response regulator
AS97_RS22205	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AS97_RS22215	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AS97_RS22220	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AS97_RS22220	COG1754	DNA topoisomerase type I activity
AS97_RS22230	COG2890	protein-(glutamine-N5) methyltransferase activity
AS97_RS22240	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AS97_RS22245	COG2172	sigma factor antagonist activity
AS97_RS22250	COG1366	Belongs to the anti-sigma-factor antagonist family
AS97_RS22255	COG1205	dead DEAH box helicase
AS97_RS22255	COG1111	helicase
AS97_RS22320	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AS97_RS22335	COG2267	carboxylic ester hydrolase activity
AS97_RS22360	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS97_RS22385	COG0003	Pfam Anion-transporting ATPase
AS97_RS22395	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AS97_RS22405	COG1408	metallophosphoesterase
AS97_RS22455	COG2124	cytochrome p450
AS97_RS22500	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AS97_RS22505	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AS97_RS22555	COG4585	Histidine kinase
AS97_RS22560	COG2197	response regulator
AS97_RS22570	COG0577	efflux transmembrane transporter activity
AS97_RS22570	COG1136	(ABC) transporter
AS97_RS22575	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AS97_RS22595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AS97_RS22610	COG3594	Acyltransferase
AS97_RS22620	COG0501	Belongs to the peptidase M48B family
AS97_RS22630	COG2124	cytochrome p450
AS97_RS22635	COG0702	epimerase
AS97_RS22650	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AS97_RS22685	COG0205	6-phosphofructokinase activity
AS97_RS22695	COG1191	sigma factor activity
AS97_RS22700	COG1191	sigma factor activity
AS97_RS22740	COG0477	Major facilitator Superfamily
AS97_RS22745	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AS97_RS22755	COG2205	protein histidine kinase activity
AS97_RS22760	COG0745	RESPONSE REGULATOR receiver
AS97_RS22795	COG0024	Methionine aminopeptidase
AS97_RS22870	COG2188	Transcriptional regulator
AS97_RS22905	COG0582	viral genome integration into host DNA
AS97_RS22925	COG5000	phosphorelay sensor kinase activity
AS97_RS22930	COG0318	PFAM AMP-dependent synthetase and ligase
AS97_RS22935	COG1595	DNA-templated transcription, initiation
AS97_RS23025	COG1403	HNH endonuclease
AS97_RS23090	COG0494	nUDIX hydrolase
AS97_RS23140	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AS97_RS23155	COG0653	protein targeting
AS97_RS23170	COG0006	proline dipeptidase activity
AS97_RS23175	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AS97_RS23180	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS97_RS23200	COG1999	signal sequence binding
AS97_RS23210	COG2372	response to copper ion
AS97_RS23215	COG2837	iron assimilation
AS97_RS23225	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AS97_RS23230	COG0561	phosphatase activity
AS97_RS23255	COG2807	transmembrane transport
AS97_RS23280	COG1131	(ABC) transporter
AS97_RS23295	COG0501	Belongs to the peptidase M48B family
AS97_RS23320	COG4988	ABC transporter
AS97_RS23325	COG1294	oxidase, subunit
AS97_RS23330	COG1271	oxidase subunit
AS97_RS23335	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AS97_RS23340	COG1609	Transcriptional regulator
AS97_RS23360	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AS97_RS23380	COG0662	Cupin 2, conserved barrel domain protein
AS97_RS23385	COG1950	PFAM Membrane protein of
AS97_RS23390	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AS97_RS23395	COG0626	cystathionine gamma-synthase activity
AS97_RS23460	COG0242	peptide deformylase activity
AS97_RS23465	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AS97_RS23495	COG0305	Participates in initiation and elongation during chromosome replication
AS97_RS23505	COG0359	binds to the 23S rRNA
AS97_RS23510	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AS97_RS23515	COG0629	single-stranded DNA binding
AS97_RS23520	COG0360	Binds together with S18 to 16S ribosomal RNA
AS97_RS23545	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AS97_RS23555	COG1260	myo-inositol-1-phosphate synthase
AS97_RS23565	COG0617	tRNA 3'-terminal CCA addition
AS97_RS23580	COG0515	serine threonine protein kinase
AS97_RS23580	COG2815	serine threonine protein kinase
AS97_RS23585	COG1595	DNA-templated transcription, initiation
AS97_RS23595	COG0492	ferredoxin-NADP+ reductase activity
AS97_RS23600	COG3118	belongs to the thioredoxin family
AS97_RS23615	COG1192	Involved in chromosome partitioning
AS97_RS23620	COG0357	Ribosomal RNA small subunit methyltransferase G
AS97_RS23630	COG0706	membrane insertase activity
AS97_RS23635	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AS97_RS23640	COG0594	ribonuclease P activity
AS97_RS23645	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AS97_RS23655	COG0592	DNA-directed DNA polymerase activity
AS97_RS23660	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AS97_RS23665	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AS97_RS23670	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
AS97_RS23675	COG0187	DNA topoisomerase II activity
AS97_RS23680	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AS97_RS23705	COG0515	serine threonine protein kinase
AS97_RS23735	COG0705	Rhomboid family
AS97_RS23750	COG3764	Sortase (surface protein transpeptidase)
AS97_RS23765	COG3764	Sortase (surface protein transpeptidase)
AS97_RS23770	COG3764	Sortase (surface protein transpeptidase)
AS97_RS23775	COG0515	serine threonine protein kinase
AS97_RS23780	COG0768	penicillin binding
AS97_RS23795	COG1716	ATPase activity
AS97_RS23800	COG1716	ATPase activity
AS97_RS23810	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AS97_RS23815	COG1733	regulation of RNA biosynthetic process
AS97_RS23830	COG0425	Belongs to the sulfur carrier protein TusA family
AS97_RS23830	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AS97_RS23840	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AS97_RS23845	COG2151	metal-sulfur cluster biosynthetic enzyme
AS97_RS23850	COG3396	Phenylacetate-CoA oxygenase
AS97_RS23855	COG3460	Phenylacetate-CoA oxygenase
AS97_RS23860	COG3396	Phenylacetate-CoA oxygenase
AS97_RS23885	COG1250	3-hydroxyacyl-CoA dehydrogenase
AS97_RS23890	COG1309	transcriptional regulator
AS97_RS23895	COG1522	sequence-specific DNA binding
AS97_RS23925	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AS97_RS23930	COG0604	alcohol dehydrogenase
AS97_RS23930	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS23930	COG3321	synthase
AS97_RS23945	COG0515	serine threonine protein kinase
AS97_RS23950	COG0515	serine threonine protein kinase
AS97_RS23970	COG0022	dehydrogenase e1 component
AS97_RS23975	COG0508	dehydrogenase complex catalyzes the overall conversion of
AS97_RS24015	COG1362	aminopeptidase activity
AS97_RS24030	COG1960	acyl-CoA dehydrogenase activity
AS97_RS24040	COG1741	Belongs to the pirin family
AS97_RS24065	COG2837	iron assimilation
AS97_RS24075	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AS97_RS24090	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AS97_RS24125	COG1793	dna ligase
AS97_RS24135	COG3290	protein histidine kinase activity
AS97_RS24145	COG2018	Roadblock/LC7 domain
AS97_RS24220	COG3938	Belongs to the proline racemase family
AS97_RS24245	COG0725	ABC transporter, periplasmic molybdate-binding protein
AS97_RS24280	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
AS97_RS24290	COG2409	Drug exporters of the RND superfamily
AS97_RS24295	COG4585	Histidine kinase
AS97_RS24300	COG2197	response regulator
AS97_RS24310	COG0583	DNA-binding transcription factor activity
AS97_RS24320	COG2268	Band 7 protein
AS97_RS24345	COG0515	serine threonine protein kinase
AS97_RS24345	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AS97_RS24400	COG4133	protoheme IX ABC transporter activity
AS97_RS24450	COG2402	Toxic component of a toxin-antitoxin (TA) module. An RNase
AS97_RS24470	COG1695	Transcriptional regulator
AS97_RS24525	COG0717	Belongs to the dCTP deaminase family
AS97_RS24530	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AS97_RS24545	COG3290	protein histidine kinase activity
AS97_RS24550	COG0247	lactate metabolic process
AS97_RS24550	COG2181	nitrate reductase activity
AS97_RS24555	COG0443	Heat shock 70 kDa protein
AS97_RS24560	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AS97_RS24565	COG0484	heat shock protein binding
AS97_RS24570	COG0789	Transcriptional regulator
AS97_RS24590	COG0542	response to heat
AS97_RS24710	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AS97_RS24750	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AS97_RS24765	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AS97_RS24770	COG0191	fructose-bisphosphate aldolase activity
AS97_RS24775	COG0477	Major facilitator Superfamily
AS97_RS24790	COG3844	kynureninase activity
AS97_RS24800	COG4585	Histidine kinase
AS97_RS24805	COG2197	response regulator
AS97_RS24810	COG2124	cytochrome p450
AS97_RS24815	COG3559	Exporter of polyketide antibiotics
AS97_RS24820	COG1131	(ABC) transporter
AS97_RS24835	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AS97_RS24850	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AS97_RS24855	COG1802	Transcriptional regulator
AS97_RS24870	COG0151	Belongs to the GarS family
AS97_RS24890	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AS97_RS24920	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AS97_RS24925	COG0047	phosphoribosylformylglycinamidine synthase activity
AS97_RS24930	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AS97_RS24950	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AS97_RS24960	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AS97_RS24985	COG1643	Atp-dependent helicase
AS97_RS25000	COG0477	Major facilitator Superfamily
AS97_RS25045	COG2188	Transcriptional regulator
AS97_RS25095	COG0582	viral genome integration into host DNA
AS97_RS25135	COG0513	Belongs to the DEAD box helicase family
AS97_RS25180	COG0667	Aldo Keto reductase
AS97_RS25210	COG0556	nucleotide-excision repair
AS97_RS25220	COG1376	ErfK ybiS ycfS ynhG family protein
AS97_RS25230	COG1595	DNA-templated transcription, initiation
AS97_RS25240	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AS97_RS25245	COG0579	oxidoreductase
AS97_RS25270	COG1252	NADH dehydrogenase
AS97_RS25285	COG1846	Transcriptional regulator
AS97_RS25340	COG0739	heme binding
AS97_RS25340	COG0741	lytic transglycosylase activity
AS97_RS25340	COG1196	nuclear chromosome segregation
AS97_RS25345	COG0671	phosphoesterase, PA-phosphatase related
AS97_RS25350	COG0277	FAD linked oxidase domain protein
AS97_RS25370	COG1937	Protein conserved in bacteria
AS97_RS25380	COG0306	phosphate transporter
AS97_RS25385	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AS97_RS25410	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AS97_RS25440	COG4941	Belongs to the sigma-70 factor family
AS97_RS25445	COG0667	Aldo Keto reductase
AS97_RS25455	COG2249	NAD(P)H dehydrogenase (quinone) activity
AS97_RS25485	COG4552	Acetyltransferase involved in intracellular survival and related
AS97_RS25495	COG1490	D-aminoacyl-tRNA deacylase activity
AS97_RS25505	COG0735	belongs to the Fur family
AS97_RS25510	COG3485	protocatechuate 3,4-dioxygenase
AS97_RS25530	COG2897	thiosulfate sulfurtransferase activity
AS97_RS25565	COG0745	RESPONSE REGULATOR receiver
AS97_RS25570	COG1609	Transcriptional regulator
AS97_RS25575	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AS97_RS25595	COG0724	RNA recognition motif
AS97_RS25605	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AS97_RS25635	COG0739	heme binding
AS97_RS25655	COG0346	lactoylglutathione lyase activity
AS97_RS25660	COG2205	protein histidine kinase activity
AS97_RS25665	COG0745	RESPONSE REGULATOR receiver
AS97_RS25675	COG1595	DNA-templated transcription, initiation
AS97_RS25680	COG1194	a g-specific adenine glycosylase
AS97_RS25690	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
AS97_RS25710	COG0248	Ppx GppA phosphatase
AS97_RS25715	COG1082	Xylose isomerase domain protein TIM barrel
AS97_RS25720	COG1309	transcriptional regulator
AS97_RS25725	COG0129	dihydroxy-acid dehydratase activity
AS97_RS25755	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AS97_RS25760	COG0180	Tryptophanyl-tRNA synthetase
AS97_RS25780	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AS97_RS25790	COG0123	including yeast histone deacetylase and acetoin utilization protein
AS97_RS25840	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AS97_RS25845	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AS97_RS25850	COG0181	hydroxymethylbilane synthase activity
AS97_RS25855	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AS97_RS25855	COG1648	precorrin-2 dehydrogenase activity
AS97_RS25860	COG0113	porphobilinogen synthase activity
AS97_RS25885	COG1072	(Pantothenic acid kinase))
AS97_RS25905	COG0018	arginyl-trna synthetase
AS97_RS25910	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
AS97_RS25930	COG1690	Belongs to the RtcB family
AS97_RS25935	COG2124	cytochrome p450
AS97_RS25940	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AS97_RS25960	COG1742	UPF0060 membrane protein
AS97_RS25980	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AS97_RS25985	COG0406	alpha-ribazole phosphatase activity
AS97_RS25995	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS97_RS26000	COG0785	Cytochrome C biogenesis protein
AS97_RS26005	COG1333	cytochrome c biogenesis protein
AS97_RS26010	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AS97_RS26020	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AS97_RS26025	COG0109	protoheme IX farnesyltransferase activity
AS97_RS26030	COG0163	prenyltransferase activity
AS97_RS26045	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AS97_RS26050	COG1573	uracil-dna glycosylase
AS97_RS26065	COG1301	dicarboxylic acid transport
AS97_RS26080	COG1309	transcriptional regulator
AS97_RS26090	COG2207	Transcriptional regulator
AS97_RS26100	COG1278	Cold shock
AS97_RS26105	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
AS97_RS26115	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AS97_RS26125	COG2226	methyltransferase
AS97_RS26145	COG1388	LysM domain
AS97_RS26145	COG3103	Sh3 type 3 domain protein
AS97_RS26145	COG0791	NLP P60 protein
AS97_RS26155	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AS97_RS26160	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AS97_RS26165	COG0649	NAD binding
AS97_RS26180	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AS97_RS26185	COG1034	ATP synthesis coupled electron transport
AS97_RS26190	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AS97_RS26195	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AS97_RS26200	COG0839	Belongs to the complex I subunit 6 family
AS97_RS26205	COG0713	ATP synthesis coupled electron transport
AS97_RS26210	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AS97_RS26220	COG1007	ATP synthesis coupled electron transport
AS97_RS26250	COG0142	geranyltranstransferase activity
AS97_RS26280	COG0702	epimerase
AS97_RS26285	COG0531	amino acid
AS97_RS26290	COG1013	pyruvate-flavodoxin oxidoreductase activity
AS97_RS26295	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AS97_RS26295	COG0674	pyruvate-flavodoxin oxidoreductase activity
AS97_RS26305	COG4585	Histidine kinase
AS97_RS26310	COG4585	Histidine kinase
AS97_RS26315	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AS97_RS26320	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AS97_RS26325	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AS97_RS26330	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AS97_RS26335	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AS97_RS26340	COG0839	Belongs to the complex I subunit 6 family
AS97_RS26345	COG0713	ATP synthesis coupled electron transport
AS97_RS26350	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AS97_RS26360	COG1007	ATP synthesis coupled electron transport
AS97_RS26365	COG0501	Belongs to the peptidase M48B family
AS97_RS26370	COG3304	Inner membrane component domain
AS97_RS26375	COG1666	GTP binding
AS97_RS26400	COG1970	mechanosensitive ion channel activity
AS97_RS26420	COG0702	epimerase
AS97_RS26440	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AS97_RS26445	COG2030	dehydratase
AS97_RS26455	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AS97_RS26460	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AS97_RS26465	COG0436	Aminotransferase
AS97_RS26485	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AS97_RS26490	COG0081	regulation of translation
AS97_RS26500	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AS97_RS26505	COG0222	ribosome binding
AS97_RS26510	COG0085	RNA polymerase activity
AS97_RS26515	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AS97_RS26530	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AS97_RS26535	COG0049	tRNA binding
AS97_RS26540	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AS97_RS26545	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AS97_RS26570	COG0051	transcription antitermination factor activity, RNA binding
AS97_RS26575	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AS97_RS26580	COG0088	Forms part of the polypeptide exit tunnel
AS97_RS26585	COG0089	rRNA binding
AS97_RS26590	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AS97_RS26595	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AS97_RS26600	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AS97_RS26605	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AS97_RS26610	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AS97_RS26615	COG0255	Belongs to the universal ribosomal protein uL29 family
AS97_RS26620	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AS97_RS26625	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AS97_RS26630	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AS97_RS26635	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AS97_RS26640	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AS97_RS26645	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AS97_RS26650	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AS97_RS26655	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AS97_RS26660	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AS97_RS26670	COG0200	Binds to the 23S rRNA
AS97_RS26680	COG0563	adenylate kinase activity
AS97_RS26690	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AS97_RS26695	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AS97_RS26700	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AS97_RS26705	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AS97_RS26710	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AS97_RS26715	COG0202	RNA polymerase activity
AS97_RS26720	COG0203	ribosomal protein L17
AS97_RS26725	COG0101	tRNA pseudouridine synthase activity
AS97_RS26730	COG1366	Belongs to the anti-sigma-factor antagonist family
AS97_RS26735	COG1366	Belongs to the anti-sigma-factor antagonist family
AS97_RS26740	COG2172	sigma factor antagonist activity
AS97_RS26750	COG2770	Histidine kinase
AS97_RS26750	COG2208	phosphoserine phosphatase activity
AS97_RS26760	COG0438	transferase activity, transferring glycosyl groups
AS97_RS26775	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AS97_RS26780	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AS97_RS26785	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AS97_RS26795	COG1072	(Pantothenic acid kinase))
AS97_RS26805	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AS97_RS26810	COG0736	holo-[acyl-carrier-protein] synthase activity
AS97_RS26860	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AS97_RS26870	COG0802	atpase or kinase
AS97_RS26895	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AS97_RS26905	COG3903	Transcriptional regulator
AS97_RS26905	COG3629	intracellular signal transduction
AS97_RS26910	COG0596	Alpha beta hydrolase
AS97_RS26965	COG0726	polysaccharide deacetylase
AS97_RS26970	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AS97_RS26975	COG0459	protein refolding
AS97_RS26980	COG4221	oxidoreductase activity
AS97_RS26990	COG0583	DNA-binding transcription factor activity
AS97_RS27000	COG2197	response regulator
AS97_RS27005	COG1595	DNA-templated transcription, initiation
AS97_RS27015	COG0516	GMP reductase activity
AS97_RS27030	COG1077	Cell shape determining protein MreB Mrl
AS97_RS27045	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AS97_RS27065	COG0318	PFAM AMP-dependent synthetase and ligase
AS97_RS27070	COG1960	acyl-CoA dehydrogenase activity
AS97_RS27075	COG1960	acyl-CoA dehydrogenase activity
AS97_RS27090	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS27095	COG1960	acyl-CoA dehydrogenase activity
AS97_RS27100	COG1012	belongs to the aldehyde dehydrogenase family
AS97_RS27110	COG4977	sequence-specific DNA binding
AS97_RS27120	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AS97_RS27125	COG1024	Enoyl-CoA hydratase
AS97_RS27135	COG2072	flavoprotein involved in K transport
AS97_RS27150	COG0259	pyridoxamine-phosphate oxidase activity
AS97_RS27160	COG1960	acyl-CoA dehydrogenase activity
AS97_RS27170	COG1309	transcriptional regulator
AS97_RS27180	COG0515	serine threonine protein kinase
AS97_RS27180	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AS97_RS27195	COG1024	Enoyl-CoA hydratase
AS97_RS27255	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AS97_RS27280	COG1695	Transcriptional regulator
AS97_RS27305	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AS97_RS27335	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS27370	COG1686	Belongs to the peptidase S11 family
AS97_RS27380	COG1653	transport
AS97_RS27400	COG0515	serine threonine protein kinase
AS97_RS27425	COG1309	transcriptional regulator
AS97_RS27435	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AS97_RS27455	COG0730	response to heat
AS97_RS27460	COG1937	Protein conserved in bacteria
AS97_RS27465	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AS97_RS27470	COG1793	dna ligase
AS97_RS27470	COG3285	dna ligase
AS97_RS27475	COG1793	dna ligase
AS97_RS27480	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AS97_RS27500	COG1250	3-hydroxyacyl-CoA dehydrogenase
AS97_RS27500	COG0824	Thioesterase
AS97_RS27505	COG1250	3-hydroxyacyl-CoA dehydrogenase
AS97_RS27510	COG3246	L-lysine catabolic process to acetate
AS97_RS27515	COG1309	transcriptional regulator
AS97_RS27520	COG0515	serine threonine protein kinase
AS97_RS27530	COG0596	Alpha beta hydrolase
AS97_RS27550	COG2378	regulation of single-species biofilm formation
AS97_RS27565	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AS97_RS27610	COG0330	HflC and HflK could
AS97_RS27635	COG3486	L-lysine 6-monooxygenase (NADPH) activity
AS97_RS27685	COG1309	transcriptional regulator
AS97_RS27705	COG1846	Transcriptional regulator
AS97_RS27710	COG3384	dioxygenase
AS97_RS27730	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS27735	COG1349	DNA-binding transcription factor activity
AS97_RS27740	COG1105	Belongs to the carbohydrate kinase PfkB family
AS97_RS27745	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AS97_RS27745	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AS97_RS27750	COG0492	ferredoxin-NADP+ reductase activity
AS97_RS27760	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AS97_RS27770	COG1970	mechanosensitive ion channel activity
AS97_RS27780	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AS97_RS27790	COG3263	regulation of cellular component size
AS97_RS27800	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AS97_RS27805	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AS97_RS27815	COG0315	cyclic pyranopterin monophosphate synthase activity
AS97_RS27820	COG0315	cyclic pyranopterin monophosphate synthase activity
AS97_RS27820	COG0521	Mo-molybdopterin cofactor biosynthetic process
AS97_RS27825	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS97_RS27840	COG0783	Belongs to the Dps family
AS97_RS27855	COG0708	Exodeoxyribonuclease III
AS97_RS27865	COG2072	flavoprotein involved in K transport
AS97_RS27870	COG2267	carboxylic ester hydrolase activity
AS97_RS27885	COG4946	Tricorn protease homolog
AS97_RS27885	COG0793	Belongs to the peptidase S41A family
AS97_RS27895	COG2409	Drug exporters of the RND superfamily
AS97_RS27900	COG0310	cobalt ion transport
AS97_RS27910	COG1122	ATPase activity
AS97_RS27950	COG4166	transmembrane transport
AS97_RS28005	COG0084	hydrolase, TatD family'
AS97_RS28010	COG3583	domain protein
AS97_RS28010	COG3584	3D domain protein
AS97_RS28015	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AS97_RS28020	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AS97_RS28025	COG0488	(ABC) transporter
AS97_RS28060	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AS97_RS28065	COG2197	response regulator
AS97_RS28075	COG4106	trans-aconitate 2-methyltransferase activity
AS97_RS28085	COG1309	transcriptional regulator
AS97_RS28095	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AS97_RS28105	COG0193	aminoacyl-tRNA hydrolase activity
AS97_RS28110	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AS97_RS28115	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AS97_RS28120	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AS97_RS28135	COG4585	Histidine kinase
AS97_RS28165	COG2814	Major facilitator Superfamily
AS97_RS28170	COG1136	(ABC) transporter
AS97_RS28175	COG0577	efflux transmembrane transporter activity
AS97_RS28180	COG0667	Aldo Keto reductase
AS97_RS28280	COG4608	Belongs to the ABC transporter superfamily
AS97_RS28300	COG0583	DNA-binding transcription factor activity
AS97_RS28310	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AS97_RS28315	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS28320	COG0583	DNA-binding transcription factor activity
AS97_RS28335	COG5002	protein histidine kinase activity
AS97_RS28340	COG2018	Roadblock/LC7 domain
AS97_RS28365	COG2378	regulation of single-species biofilm formation
AS97_RS28375	COG0789	Transcriptional regulator
AS97_RS28390	COG2304	oxidoreductase activity
AS97_RS28400	COG2770	Histidine kinase
AS97_RS28400	COG2208	phosphoserine phosphatase activity
AS97_RS28440	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AS97_RS28470	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AS97_RS28485	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AS97_RS28495	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AS97_RS28505	COG3903	Transcriptional regulator
AS97_RS28505	COG3629	intracellular signal transduction
AS97_RS28515	COG1331	Highly conserved protein containing a thioredoxin domain
AS97_RS28525	COG1272	protein, Hemolysin III
AS97_RS28530	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
AS97_RS28550	COG0601	transmembrane transport
AS97_RS28555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AS97_RS28580	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AS97_RS28595	COG1414	Transcriptional regulator
AS97_RS28605	COG2610	gluconate transmembrane transporter activity
AS97_RS28610	COG1131	(ABC) transporter
AS97_RS28675	COG2894	cell division
AS97_RS28715	COG2885	chlorophyll binding
AS97_RS28720	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AS97_RS28725	COG1278	Cold shock
AS97_RS28740	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AS97_RS28745	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AS97_RS28760	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AS97_RS28765	COG0450	alkyl hydroperoxide reductase
AS97_RS28785	COG1136	(ABC) transporter
AS97_RS28805	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AS97_RS28815	COG3185	4-Hydroxyphenylpyruvate dioxygenase
AS97_RS28815	COG1082	Xylose isomerase domain protein TIM barrel
AS97_RS28820	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AS97_RS28825	COG1309	transcriptional regulator
AS97_RS28835	COG2226	methyltransferase
AS97_RS28845	COG0114	fumarate hydratase activity
AS97_RS28860	COG3469	chitinase activity
AS97_RS28865	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AS97_RS28865	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AS97_RS28890	COG0778	Nitroreductase
AS97_RS28895	COG1722	exodeoxyribonuclease VII activity
AS97_RS28900	COG1570	exodeoxyribonuclease VII activity
AS97_RS28905	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AS97_RS28920	COG0012	GTP binding
AS97_RS28925	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AS97_RS28935	COG3547	Transposase (IS116 IS110 IS902 family)
AS97_RS28950	COG0582	viral genome integration into host DNA
AS97_RS28955	COG1201	RNA secondary structure unwinding
AS97_RS29030	COG0028	Belongs to the TPP enzyme family
AS97_RS29045	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AS97_RS29065	COG1349	DNA-binding transcription factor activity
AS97_RS29110	COG0142	geranyltranstransferase activity
AS97_RS29125	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
AS97_RS29130	COG4221	oxidoreductase activity
AS97_RS29135	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS29145	COG0583	DNA-binding transcription factor activity
AS97_RS29160	COG0531	amino acid
AS97_RS29185	COG1053	succinate dehydrogenase
AS97_RS29205	COG1217	gtp-binding protein TYPA
AS97_RS29215	COG0601	transmembrane transport
AS97_RS29220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AS97_RS29225	COG0444	Belongs to the ABC transporter superfamily
AS97_RS29230	COG4608	Belongs to the ABC transporter superfamily
AS97_RS29275	COG0596	Alpha beta hydrolase
AS97_RS29280	COG4166	transmembrane transport
AS97_RS29285	COG0601	transmembrane transport
AS97_RS29290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AS97_RS29300	COG4608	Belongs to the ABC transporter superfamily
AS97_RS29315	COG4608	Belongs to the ABC transporter superfamily
AS97_RS29320	COG0444	Belongs to the ABC transporter superfamily
AS97_RS29330	COG0747	negative chemotaxis
AS97_RS29335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AS97_RS29355	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AS97_RS29370	COG1131	(ABC) transporter
AS97_RS29380	COG4585	Histidine kinase
AS97_RS29385	COG2197	response regulator
AS97_RS29420	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AS97_RS29425	COG1611	Belongs to the LOG family
AS97_RS29430	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AS97_RS29440	COG0519	Catalyzes the synthesis of GMP from XMP
AS97_RS29445	COG1024	Enoyl-CoA hydratase
AS97_RS29460	COG1595	DNA-templated transcription, initiation
AS97_RS29470	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AS97_RS29475	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AS97_RS29515	COG0598	Magnesium transport protein CorA
AS97_RS29535	COG2095	MarC family integral membrane protein
AS97_RS29545	COG1432	Conserved Protein
AS97_RS29550	COG0596	Alpha beta hydrolase
AS97_RS29685	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AS97_RS29735	COG3480	Lon protease (S16) C-terminal proteolytic domain
AS97_RS29745	COG1615	UPF0182 protein
AS97_RS29770	COG0753	catalase activity
AS97_RS29780	COG0483	inositol monophosphate 1-phosphatase activity
AS97_RS29790	COG2076	Multidrug Resistance protein
AS97_RS29800	COG1162	GTPase activity
AS97_RS29805	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AS97_RS29815	COG2135	peptidase activity
AS97_RS29825	COG1595	DNA-templated transcription, initiation
AS97_RS29830	COG5662	AntiSigma factor
AS97_RS29835	COG2199	diguanylate cyclase activity
AS97_RS29835	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AS97_RS29850	COG0242	peptide deformylase activity
AS97_RS29855	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AS97_RS29935	COG2188	Transcriptional regulator
AS97_RS29940	COG2182	Extracellular solute-binding protein
AS97_RS29945	COG1175	transmembrane transport
AS97_RS29950	COG0395	ABC-type sugar transport system, permease component
AS97_RS29955	COG1472	Belongs to the glycosyl hydrolase 3 family
AS97_RS29960	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AS97_RS29975	COG1597	lipid kinase activity
AS97_RS30020	COG2066	Belongs to the glutaminase family
AS97_RS30040	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AS97_RS30065	COG5640	endopeptidase activity
AS97_RS30070	COG0583	DNA-binding transcription factor activity
AS97_RS30115	COG0765	amino acid transport
AS97_RS30125	COG0281	malic enzyme
AS97_RS30150	COG3321	synthase
AS97_RS30150	COG0300	oxidoreductase activity
AS97_RS30150	COG0318	PFAM AMP-dependent synthetase and ligase
AS97_RS30150	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS30150	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS97_RS30165	COG0778	Nitroreductase
AS97_RS30190	COG0789	Transcriptional regulator
AS97_RS30195	COG0567	Dehydrogenase, E1 component
AS97_RS30195	COG0508	dehydrogenase complex catalyzes the overall conversion of
AS97_RS30200	COG2205	protein histidine kinase activity
AS97_RS30205	COG0745	RESPONSE REGULATOR receiver
AS97_RS30220	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AS97_RS30230	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS30235	COG2249	NAD(P)H dehydrogenase (quinone) activity
AS97_RS30240	COG1309	transcriptional regulator
AS97_RS30285	COG3103	Sh3 type 3 domain protein
AS97_RS30285	COG1388	LysM domain
AS97_RS30285	COG0791	NLP P60 protein
AS97_RS30325	COG0477	Major facilitator Superfamily
AS97_RS30345	COG3903	Transcriptional regulator
AS97_RS30345	COG3629	intracellular signal transduction
AS97_RS30370	COG4585	Histidine kinase
AS97_RS30375	COG2197	response regulator
AS97_RS30470	COG1733	regulation of RNA biosynthetic process
AS97_RS30505	COG0745	RESPONSE REGULATOR receiver
AS97_RS30510	COG0018	arginyl-trna synthetase
AS97_RS30510	COG0018	arginyl-trna synthetase
AS97_RS30515	COG0019	diaminopimelate decarboxylase activity
AS97_RS30520	COG0460	homoserine dehydrogenase
AS97_RS30525	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AS97_RS30530	COG0083	homoserine kinase activity
AS97_RS30540	COG1316	TRANSCRIPTIONal
AS97_RS30545	COG0254	rRNA binding
AS97_RS30550	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AS97_RS30555	COG2890	protein-(glutamine-N5) methyltransferase activity
AS97_RS30565	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AS97_RS30570	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AS97_RS30575	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AS97_RS30590	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AS97_RS30595	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AS97_RS30600	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AS97_RS30605	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AS97_RS30610	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AS97_RS30615	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AS97_RS30620	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AS97_RS30630	COG2197	response regulator
AS97_RS30635	COG4585	Histidine kinase
AS97_RS30665	COG1250	3-hydroxyacyl-CoA dehydrogenase
AS97_RS30680	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
AS97_RS30730	COG0183	Belongs to the thiolase family
AS97_RS30745	COG0745	RESPONSE REGULATOR receiver
AS97_RS30750	COG2205	protein histidine kinase activity
AS97_RS30805	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AS97_RS30805	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AS97_RS30840	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AS97_RS30845	COG0857	belongs to the CobB CobQ family
AS97_RS30845	COG0280	phosphate acetyltransferase
AS97_RS30850	COG0205	6-phosphofructokinase activity
AS97_RS30870	COG3833	ABC-type maltose transport systems, permease component
AS97_RS30875	COG1316	TRANSCRIPTIONal
AS97_RS30895	COG1309	transcriptional regulator
AS97_RS30935	COG1309	transcriptional regulator
AS97_RS30940	COG1175	transmembrane transport
AS97_RS30950	COG3469	chitinase activity
AS97_RS30955	COG4565	transcriptional regulatory protein
AS97_RS30960	COG4191	Histidine kinase
AS97_RS30965	COG1301	dicarboxylic acid transport
AS97_RS30975	COG3629	intracellular signal transduction
AS97_RS30975	COG3903	Transcriptional regulator
AS97_RS30980	COG0395	ABC-type sugar transport system, permease component
AS97_RS30985	COG1175	transmembrane transport
AS97_RS30990	COG1653	transport
AS97_RS31000	COG2186	Transcriptional regulator
AS97_RS31005	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AS97_RS31010	COG3281	Trehalose synthase
AS97_RS31020	COG0366	Alpha amylase catalytic
AS97_RS31040	COG3401	FG-GAP repeat protein
AS97_RS31045	COG0058	SHG alpha-glucan phosphorylase activity
AS97_RS31110	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AS97_RS31130	COG2318	DinB family
AS97_RS31135	COG3340	Belongs to the peptidase S51 family
AS97_RS31175	COG1132	(ABC) transporter
AS97_RS31180	COG1132	(ABC) transporter
AS97_RS31255	COG3209	COG3209 Rhs family protein
AS97_RS31260	COG1595	DNA-templated transcription, initiation
AS97_RS31275	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AS97_RS31310	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AS97_RS31325	COG1760	l-serine dehydratase
AS97_RS31330	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AS97_RS31335	COG0509	glycine decarboxylation via glycine cleavage system
AS97_RS31340	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AS97_RS31365	COG4166	transmembrane transport
AS97_RS31375	COG0444	Belongs to the ABC transporter superfamily
AS97_RS31380	COG4608	Belongs to the ABC transporter superfamily
AS97_RS31385	COG2860	membrane
AS97_RS31425	COG0482	sulfurtransferase activity
AS97_RS31440	COG1819	glycosyl
AS97_RS31470	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AS97_RS31490	COG0300	oxidoreductase activity
AS97_RS31500	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AS97_RS31510	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AS97_RS31515	COG0154	amidase activity
AS97_RS31525	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AS97_RS31535	COG2409	Drug exporters of the RND superfamily
AS97_RS31545	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AS97_RS31545	COG1672	PFAM Archaeal ATPase
AS97_RS31555	COG2133	pyrroloquinoline quinone binding
AS97_RS31560	COG0667	Aldo Keto reductase
AS97_RS31580	COG0440	acetolactate synthase activity
AS97_RS31585	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AS97_RS31590	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AS97_RS31625	COG0477	Major facilitator Superfamily
AS97_RS31640	COG0506	proline dehydrogenase activity
AS97_RS31645	COG1012	belongs to the aldehyde dehydrogenase family
AS97_RS31655	COG0473	3-isopropylmalate dehydrogenase activity
AS97_RS31660	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AS97_RS31665	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AS97_RS31670	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AS97_RS31690	COG2018	Roadblock/LC7 domain
AS97_RS31710	COG2018	Roadblock/LC7 domain
AS97_RS31715	COG5002	protein histidine kinase activity
AS97_RS31725	COG0179	Fumarylacetoacetate (FAA) hydrolase
AS97_RS31730	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AS97_RS31770	COG1414	Transcriptional regulator
AS97_RS31775	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AS97_RS31780	COG0066	3-isopropylmalate dehydratase activity
AS97_RS31790	COG0776	regulation of translation
AS97_RS31795	COG1920	GTP binding
AS97_RS31805	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AS97_RS31810	COG1181	Belongs to the D-alanine--D-alanine ligase family
AS97_RS31830	COG0351	phosphomethylpyrimidine kinase
AS97_RS31835	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AS97_RS31840	COG1461	Dihydroxyacetone kinase
AS97_RS31850	COG0742	ribosomal rna small subunit methyltransferase
AS97_RS31855	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AS97_RS31870	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AS97_RS31875	COG0571	ribonuclease III activity
AS97_RS31880	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AS97_RS31885	COG1733	regulation of RNA biosynthetic process
AS97_RS31890	COG2340	Cysteine-rich secretory protein family
AS97_RS31895	COG1254	Belongs to the acylphosphatase family
AS97_RS31905	COG1196	nuclear chromosome segregation
AS97_RS31910	COG0477	Major facilitator Superfamily
AS97_RS31930	COG4585	Histidine kinase
AS97_RS31965	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AS97_RS31980	COG0442	prolyl-tRNA aminoacylation
AS97_RS31990	COG0228	four-way junction DNA binding
AS97_RS31995	COG1837	Belongs to the UPF0109 family
AS97_RS32000	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AS97_RS32005	COG0336	Belongs to the RNA methyltransferase TrmD family
AS97_RS32010	COG0335	large ribosomal subunit rRNA binding
AS97_RS32015	COG0681	Belongs to the peptidase S26 family
AS97_RS32020	COG0681	Belongs to the peptidase S26 family
AS97_RS32025	COG0681	Belongs to the peptidase S26 family
AS97_RS32030	COG0681	Belongs to the peptidase S26 family
AS97_RS32035	COG1051	belongs to the nudix hydrolase family
AS97_RS32045	COG0792	nuclease activity
AS97_RS32060	COG1191	sigma factor activity
AS97_RS32075	COG0052	Belongs to the universal ribosomal protein uS2 family
AS97_RS32080	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AS97_RS32085	COG0528	UMP kinase activity
AS97_RS32090	COG0233	cytoplasmic translational termination
AS97_RS32095	COG0575	Belongs to the CDS family
AS97_RS32100	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AS97_RS32110	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AS97_RS32115	COG3842	ATPase activity
AS97_RS32130	COG1136	(ABC) transporter
AS97_RS32135	COG0028	Belongs to the TPP enzyme family
AS97_RS32150	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AS97_RS32160	COG1012	belongs to the aldehyde dehydrogenase family
AS97_RS32175	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AS97_RS32190	COG1012	belongs to the aldehyde dehydrogenase family
AS97_RS32200	COG3842	ATPase activity
AS97_RS32205	COG1176	ABC-type spermidine putrescine transport system, permease component I
AS97_RS32210	COG1177	transmembrane transport
AS97_RS32215	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AS97_RS32235	COG2508	Transcriptional regulator
AS97_RS32240	COG1012	belongs to the aldehyde dehydrogenase family
AS97_RS32265	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AS97_RS32270	COG0750	zinc metalloprotease
AS97_RS32275	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AS97_RS32290	COG0442	prolyl-tRNA aminoacylation
AS97_RS32310	COG0779	Required for maturation of 30S ribosomal subunits
AS97_RS32325	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AS97_RS32335	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AS97_RS32340	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AS97_RS32350	COG0455	bacterial-type flagellum organization
AS97_RS32370	COG1404	Belongs to the peptidase S8 family
AS97_RS32395	COG1404	Belongs to the peptidase S8 family
AS97_RS32425	COG1674	ftsk spoiiie
AS97_RS32440	COG1404	Belongs to the peptidase S8 family
AS97_RS32495	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AS97_RS32500	COG1185	polyribonucleotide nucleotidyltransferase activity
AS97_RS32505	COG0612	Peptidase, M16
AS97_RS32510	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AS97_RS32530	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
AS97_RS32535	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AS97_RS32540	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AS97_RS32575	COG2205	protein histidine kinase activity
AS97_RS32575	COG3850	Histidine kinase
AS97_RS32575	COG4999	Histidine kinase
AS97_RS32575	COG3437	response regulator, receiver
AS97_RS32585	COG1674	ftsk spoiiie
AS97_RS32595	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AS97_RS32605	COG1058	Belongs to the CinA family
AS97_RS32605	COG1546	Belongs to the CinA family
AS97_RS32610	COG1396	sequence-specific DNA binding
AS97_RS32620	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AS97_RS32625	COG1201	RNA secondary structure unwinding
AS97_RS32670	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AS97_RS32680	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AS97_RS32685	COG0765	amino acid transport
AS97_RS32690	COG0765	amino acid transport
AS97_RS32695	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AS97_RS32700	COG1126	abc transporter atp-binding protein
AS97_RS32710	COG2205	protein histidine kinase activity
AS97_RS32715	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AS97_RS32725	COG1414	Transcriptional regulator
AS97_RS32730	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AS97_RS32750	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AS97_RS32760	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AS97_RS32765	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AS97_RS32775	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AS97_RS32790	COG1335	isochorismatase
AS97_RS32840	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AS97_RS32845	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AS97_RS32850	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AS97_RS32865	COG0488	(ABC) transporter
AS97_RS32880	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AS97_RS32910	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AS97_RS32915	COG1802	Transcriptional regulator
AS97_RS32920	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AS97_RS32935	COG0187	DNA topoisomerase II activity
AS97_RS32945	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AS97_RS32950	COG4565	transcriptional regulatory protein
AS97_RS32955	COG3290	protein histidine kinase activity
AS97_RS32970	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AS97_RS32975	COG0612	Peptidase, M16
AS97_RS32990	COG1802	Transcriptional regulator
AS97_RS32995	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AS97_RS33000	COG1042	CoA-binding domain protein
AS97_RS33000	COG0045	succinate-CoA ligase (ADP-forming) activity
AS97_RS33000	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS97_RS33015	COG1435	thymidine kinase activity
AS97_RS33050	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AS97_RS33065	COG0745	RESPONSE REGULATOR receiver
AS97_RS33070	COG2205	protein histidine kinase activity
AS97_RS33095	COG0756	dUTP diphosphatase activity
AS97_RS33135	COG0569	domain protein
AS97_RS33165	COG0531	amino acid
AS97_RS33170	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AS97_RS33175	COG2409	Drug exporters of the RND superfamily
AS97_RS33205	COG2040	homocysteine
AS97_RS33215	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AS97_RS33245	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AS97_RS33270	COG4948	Mandelate Racemase Muconate Lactonizing
AS97_RS33275	COG2186	Transcriptional regulator
AS97_RS33310	COG1309	transcriptional regulator
AS97_RS33320	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AS97_RS33340	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AS97_RS33350	COG3537	Alpha-1,2-mannosidase
AS97_RS33355	COG0702	epimerase
AS97_RS33360	COG1733	regulation of RNA biosynthetic process
AS97_RS33365	COG1335	isochorismatase
AS97_RS33380	COG1653	transport
AS97_RS33385	COG1175	transmembrane transport
AS97_RS33390	COG0395	ABC-type sugar transport system, permease component
AS97_RS33395	COG1940	carbohydrate kinase activity
AS97_RS33400	COG4213	ABC transporter substrate-binding protein
AS97_RS33410	COG4214	carbohydrate transport
AS97_RS33415	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AS97_RS33420	COG0531	amino acid
AS97_RS33435	COG1250	3-hydroxyacyl-CoA dehydrogenase
AS97_RS33435	COG1024	Enoyl-CoA hydratase
AS97_RS33440	COG0183	Belongs to the thiolase family
AS97_RS33445	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AS97_RS33460	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AS97_RS33470	COG0446	pyridine nucleotide-disulphide oxidoreductase
AS97_RS33490	COG1414	Transcriptional regulator
AS97_RS33495	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AS97_RS33500	COG3253	May function as heme-dependent peroxidase
AS97_RS33520	COG3220	belongs to the UPF0276 family
AS97_RS33525	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AS97_RS33570	COG0745	RESPONSE REGULATOR receiver
AS97_RS33575	COG5002	protein histidine kinase activity
AS97_RS33625	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AS97_RS33630	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AS97_RS33675	COG1119	ATPase activity
AS97_RS33680	COG2188	Transcriptional regulator
AS97_RS33700	COG1175	transmembrane transport
AS97_RS33720	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AS97_RS33725	COG2409	Drug exporters of the RND superfamily
AS97_RS33750	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS33760	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AS97_RS33765	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AS97_RS33790	COG0529	Catalyzes the synthesis of activated sulfate
AS97_RS33795	COG0175	sulfate reduction
AS97_RS33805	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AS97_RS33830	COG1162	GTPase activity
AS97_RS33840	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AS97_RS33850	COG0028	Belongs to the TPP enzyme family
AS97_RS33870	COG1802	Transcriptional regulator
AS97_RS33880	COG3835	regulator
AS97_RS33890	COG2080	2 iron, 2 sulfur cluster binding
AS97_RS33895	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AS97_RS33920	COG0598	Magnesium transport protein CorA
AS97_RS33925	COG2197	response regulator
AS97_RS33930	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AS97_RS33935	COG0318	PFAM AMP-dependent synthetase and ligase
AS97_RS33965	COG2351	hydroxyisourate hydrolase activity
AS97_RS33980	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AS97_RS33985	COG0746	molybdenum cofactor guanylyltransferase activity
AS97_RS33995	COG1414	Transcriptional regulator
AS97_RS34005	COG4266	Belongs to the allantoicase family
AS97_RS34040	COG0800	Aldolase
AS97_RS34060	COG2188	Transcriptional regulator
AS97_RS34080	COG1940	carbohydrate kinase activity
AS97_RS34100	COG1012	belongs to the aldehyde dehydrogenase family
AS97_RS34115	COG0535	radical SAM domain protein
AS97_RS34145	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AS97_RS34150	COG0563	adenylate kinase activity
AS97_RS34155	COG3284	Transcriptional regulator
AS97_RS34160	COG1063	alcohol dehydrogenase
AS97_RS34185	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AS97_RS34190	COG3199	ATP-NAD kinase
AS97_RS34195	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AS97_RS34200	COG0022	dehydrogenase e1 component
AS97_RS34240	COG0477	Major facilitator Superfamily
AS97_RS34245	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS34260	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AS97_RS34265	COG1113	amino acid transport
AS97_RS34295	COG2197	response regulator
AS97_RS34315	COG0577	efflux transmembrane transporter activity
AS97_RS34315	COG1136	(ABC) transporter
AS97_RS34320	COG0577	efflux transmembrane transporter activity
AS97_RS34325	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AS97_RS34345	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AS97_RS34370	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AS97_RS34410	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AS97_RS34435	COG1126	abc transporter atp-binding protein
AS97_RS34440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AS97_RS34445	COG0765	amino acid transport
AS97_RS34450	COG0765	amino acid transport
AS97_RS34485	COG0405	Gamma-glutamyltransferase
AS97_RS34515	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AS97_RS34520	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AS97_RS34530	COG1953	Uracil, thiamine, allantoin
AS97_RS34545	COG0483	inositol monophosphate 1-phosphatase activity
AS97_RS34555	COG0181	hydroxymethylbilane synthase activity
AS97_RS34590	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AS97_RS34615	COG1929	Belongs to the glycerate kinase type-1 family
AS97_RS34635	COG0688	phosphatidylethanolamine metabolic process
AS97_RS34640	COG1960	acyl-CoA dehydrogenase activity
AS97_RS34650	COG2301	Belongs to the HpcH HpaI aldolase family
AS97_RS34655	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AS97_RS34655	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AS97_RS34670	COG1309	transcriptional regulator
AS97_RS34710	COG2362	D-Aminopeptidase
AS97_RS34715	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AS97_RS34750	COG4106	trans-aconitate 2-methyltransferase activity
AS97_RS34755	COG0516	GMP reductase activity
AS97_RS34755	COG0517	IMP dehydrogenase activity
AS97_RS34785	COG0693	protein deglycase activity
AS97_RS34790	COG0028	Belongs to the TPP enzyme family
AS97_RS34795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS97_RS34850	COG2867	negative regulation of translational initiation
AS97_RS34855	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AS97_RS34895	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AS97_RS34940	COG4213	ABC transporter substrate-binding protein
AS97_RS34950	COG4214	carbohydrate transport
AS97_RS34965	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AS97_RS34975	COG0531	amino acid
AS97_RS35015	COG2154	pterin-4-alpha-carbinolamine dehydratase
AS97_RS35030	COG1595	DNA-templated transcription, initiation
AS97_RS35040	COG0656	L-ascorbic acid biosynthetic process
AS97_RS35060	COG0583	DNA-binding transcription factor activity
AS97_RS35070	COG2226	methyltransferase
AS97_RS35105	COG1309	transcriptional regulator
AS97_RS35110	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AS97_RS35125	COG3383	formate dehydrogenase (NAD+) activity
AS97_RS35140	COG0222	ribosome binding
AS97_RS35145	COG1940	carbohydrate kinase activity
AS97_RS35150	COG1129	ABC transporter
AS97_RS35155	COG1172	Belongs to the binding-protein-dependent transport system permease family
AS97_RS35160	COG1879	ABC-type sugar transport system periplasmic component
AS97_RS35165	COG0673	inositol 2-dehydrogenase activity
AS97_RS35235	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AS97_RS35245	COG0045	succinate-CoA ligase (ADP-forming) activity
AS97_RS35355	COG2226	methyltransferase
AS97_RS35360	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS97_RS35395	COG0714	Associated with various cellular activities
AS97_RS35495	COG4948	Mandelate Racemase Muconate Lactonizing
AS97_RS35510	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AS97_RS35530	COG0789	Transcriptional regulator
AS97_RS35540	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AS97_RS35600	COG1674	ftsk spoiiie
AS97_RS35615	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AS97_RS35625	COG1205	dead DEAH box helicase
AS97_RS35625	COG1111	helicase
AS97_RS35660	COG2755	lipolytic protein G-D-S-L family
AS97_RS35690	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AS97_RS35695	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AS97_RS35760	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AS97_RS35765	COG3835	regulator
AS97_RS35770	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AS97_RS35775	COG2271	Major facilitator Superfamily
AS97_RS35800	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AS97_RS35815	COG0179	Fumarylacetoacetate (FAA) hydrolase
AS97_RS35845	COG0248	Ppx GppA phosphatase
AS97_RS35855	COG2890	protein-(glutamine-N5) methyltransferase activity
AS97_RS35870	COG0519	Catalyzes the synthesis of GMP from XMP
AS97_RS35885	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AS97_RS35895	COG1609	Transcriptional regulator
AS97_RS35905	COG0667	Aldo Keto reductase
AS97_RS35910	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AS97_RS35915	COG2205	protein histidine kinase activity
AS97_RS35930	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AS97_RS35940	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AS97_RS35945	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AS97_RS35950	COG0519	Catalyzes the synthesis of GMP from XMP
AS97_RS35955	COG0667	Aldo Keto reductase
AS97_RS35965	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS35995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AS97_RS36000	COG0444	Belongs to the ABC transporter superfamily
AS97_RS36020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS97_RS36030	COG0431	NADPH-dependent FMN reductase
AS97_RS36060	COG1012	belongs to the aldehyde dehydrogenase family
AS97_RS36110	COG1515	deoxyribonuclease V activity
AS97_RS36120	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AS97_RS36130	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AS97_RS36135	COG0183	Belongs to the thiolase family
AS97_RS36140	COG1024	Enoyl-CoA hydratase
AS97_RS36140	COG1250	3-hydroxyacyl-CoA dehydrogenase
AS97_RS36145	COG0583	DNA-binding transcription factor activity
AS97_RS36155	COG0789	Transcriptional regulator
AS97_RS36170	COG0308	aminopeptidase N
AS97_RS36175	COG2936	dipeptidyl-peptidase activity
AS97_RS36185	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AS97_RS36195	COG2183	response to ionizing radiation
AS97_RS36210	COG1024	Enoyl-CoA hydratase
AS97_RS36220	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AS97_RS36265	COG1134	teichoic acid transport
AS97_RS36285	COG1562	ergosterol biosynthetic process
AS97_RS36295	COG1233	COG1233 Phytoene dehydrogenase and related
AS97_RS36305	COG1657	PFAM Prenyltransferase squalene oxidase
AS97_RS36320	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AS97_RS36325	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AS97_RS36340	COG2365	Tyrosine phosphatase family
AS97_RS36350	COG2755	lipolytic protein G-D-S-L family
AS97_RS36400	COG0596	Alpha beta hydrolase
AS97_RS36405	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AS97_RS36410	COG0531	amino acid
AS97_RS36425	COG1012	belongs to the aldehyde dehydrogenase family
AS97_RS36465	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AS97_RS36475	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AS97_RS36480	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AS97_RS36485	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AS97_RS36490	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AS97_RS36495	COG5002	protein histidine kinase activity
AS97_RS36500	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AS97_RS36505	COG0072	phenylalanine-tRNA ligase activity
AS97_RS36505	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AS97_RS36530	COG1285	pathogenesis
AS97_RS36545	COG1649	PFAM Uncharacterised BCR, COG1649
AS97_RS36555	COG0697	spore germination
AS97_RS36605	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AS97_RS36610	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AS97_RS36615	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AS97_RS36620	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AS97_RS36625	COG1438	arginine binding
AS97_RS36630	COG0385	Bile acid
AS97_RS36645	COG1477	protein flavinylation
AS97_RS36675	COG0137	argininosuccinate synthase activity
AS97_RS36680	COG0165	Argininosuccinate lyase
AS97_RS36695	COG0204	Acyl-transferase
AS97_RS36695	COG0318	PFAM AMP-dependent synthetase and ligase
AS97_RS36735	COG2011	ABC-type metal ion transport system permease component
AS97_RS36740	COG1464	Belongs to the NlpA lipoprotein family
AS97_RS36755	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AS97_RS36760	COG1648	precorrin-2 dehydrogenase activity
AS97_RS36760	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AS97_RS36785	COG2814	Major facilitator Superfamily
AS97_RS36795	COG1309	transcriptional regulator
AS97_RS36840	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AS97_RS36840	COG0512	Glutamine amidotransferase of anthranilate synthase
AS97_RS36915	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AS97_RS36930	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AS97_RS36950	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AS97_RS36955	COG1560	Kdo2-lipid A biosynthetic process
AS97_RS36960	COG0438	transferase activity, transferring glycosyl groups
AS97_RS36970	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
AS97_RS36975	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
AS97_RS36980	COG0217	transcriptional regulatory protein
AS97_RS36985	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AS97_RS36990	COG0632	four-way junction helicase activity
AS97_RS36995	COG2255	four-way junction helicase activity
AS97_RS37005	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AS97_RS37010	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AS97_RS37015	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AS97_RS37020	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AS97_RS37025	COG1196	nuclear chromosome segregation
AS97_RS37030	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AS97_RS37040	COG0124	histidyl-tRNA synthetase
AS97_RS37080	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AS97_RS37095	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AS97_RS37100	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AS97_RS37110	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AS97_RS37115	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AS97_RS37120	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AS97_RS37125	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AS97_RS37135	COG0006	proline dipeptidase activity
AS97_RS37140	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AS97_RS37145	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AS97_RS37155	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AS97_RS37160	COG0540	Belongs to the ATCase OTCase family
AS97_RS37165	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AS97_RS37175	COG0505	Belongs to the CarA family
AS97_RS37180	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AS97_RS37185	COG0167	dihydroorotate dehydrogenase activity
AS97_RS37190	COG0284	orotidine-5'-phosphate decarboxylase activity
AS97_RS37200	COG0194	GDP metabolic process
AS97_RS37215	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AS97_RS37230	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AS97_RS37235	COG1132	(ABC) transporter
AS97_RS37250	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AS97_RS37255	COG2390	Transcriptional regulator
AS97_RS37290	COG0531	amino acid
AS97_RS37300	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AS97_RS37325	COG2233	PERMEase
AS97_RS37335	COG0738	Major facilitator superfamily
AS97_RS37340	COG1940	carbohydrate kinase activity
AS97_RS37340	COG1846	Transcriptional regulator
AS97_RS37360	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AS97_RS37360	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AS97_RS37365	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AS97_RS37370	COG0140	phosphoribosyl-ATP diphosphatase activity
AS97_RS37375	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AS97_RS37430	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS37440	COG0673	inositol 2-dehydrogenase activity
AS97_RS37455	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AS97_RS37470	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AS97_RS37525	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AS97_RS37530	COG2315	Protein conserved in bacteria
AS97_RS37550	COG0436	Aminotransferase
AS97_RS37575	COG1733	regulation of RNA biosynthetic process
AS97_RS37610	COG3835	regulator
AS97_RS37650	COG2175	clavaminate synthase activity
AS97_RS37665	COG2124	cytochrome p450
AS97_RS37730	COG2132	Multicopper oxidase
AS97_RS37740	COG1012	belongs to the aldehyde dehydrogenase family
AS97_RS37755	COG1960	acyl-CoA dehydrogenase activity
AS97_RS37780	COG0463	Glycosyl transferase, family 2
AS97_RS37790	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AS97_RS37795	COG1006	Multisubunit Na H antiporter MnhC subunit
AS97_RS37800	COG2111	Na H antiporter
AS97_RS37830	COG2364	Membrane
AS97_RS37835	COG2186	Transcriptional regulator
AS97_RS37855	COG1940	carbohydrate kinase activity
AS97_RS37875	COG2207	Transcriptional regulator
AS97_RS37880	COG0154	amidase activity
AS97_RS37900	COG1940	carbohydrate kinase activity
AS97_RS37915	COG1556	Lactate utilization protein
AS97_RS37920	COG1139	Iron-sulfur cluster binding protein
AS97_RS37925	COG0247	lactate metabolic process
AS97_RS37930	COG1070	Carbohydrate kinase
AS97_RS37935	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS37935	COG3347	Dehydrogenase
AS97_RS37945	COG3250	beta-galactosidase activity
AS97_RS37960	COG1172	Belongs to the binding-protein-dependent transport system permease family
AS97_RS37980	COG3254	rhamnose metabolic process
AS97_RS37985	COG1609	Transcriptional regulator
AS97_RS37990	COG1609	Transcriptional regulator
AS97_RS38000	COG2072	flavoprotein involved in K transport
AS97_RS38025	COG0596	Alpha beta hydrolase
AS97_RS38035	COG2264	protein methyltransferase activity
AS97_RS38040	COG0596	Alpha beta hydrolase
AS97_RS38045	COG3971	2-oxopent-4-enoate hydratase activity
AS97_RS38050	COG4569	acetaldehyde dehydrogenase (acetylating) activity
AS97_RS38055	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AS97_RS38080	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AS97_RS38095	COG1175	transmembrane transport
AS97_RS38100	COG0395	ABC-type sugar transport system, permease component
AS97_RS38110	COG1874	Beta-galactosidase
AS97_RS38115	COG1472	Belongs to the glycosyl hydrolase 3 family
AS97_RS38130	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AS97_RS38210	COG0604	alcohol dehydrogenase
AS97_RS38230	COG2409	Drug exporters of the RND superfamily
AS97_RS38250	COG0604	alcohol dehydrogenase
AS97_RS38250	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS38250	COG3321	synthase
AS97_RS38325	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AS97_RS38340	COG0642	Histidine kinase
AS97_RS38345	COG2018	Roadblock/LC7 domain
AS97_RS38370	COG0395	ABC-type sugar transport system, permease component
AS97_RS38375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AS97_RS38435	COG4565	transcriptional regulatory protein
AS97_RS38440	COG3290	protein histidine kinase activity
AS97_RS38460	COG1070	Carbohydrate kinase
AS97_RS38480	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AS97_RS38485	COG2226	methyltransferase
AS97_RS38490	COG2267	carboxylic ester hydrolase activity
AS97_RS38505	COG0667	Aldo Keto reductase
AS97_RS38510	COG0640	Transcriptional regulator
AS97_RS38570	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AS97_RS38580	COG1968	undecaprenyl-diphosphatase activity
AS97_RS38600	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AS97_RS38645	COG3336	cytochrome c oxidase
AS97_RS38700	COG1832	CoA-binding protein
AS97_RS38705	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS97_RS38710	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AS97_RS38735	COG1739	Uncharacterized protein family UPF0029
AS97_RS38740	COG0420	3'-5' exonuclease activity
AS97_RS38745	COG0419	ATPase involved in DNA repair
AS97_RS38780	COG2267	carboxylic ester hydrolase activity
AS97_RS38785	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS38790	COG2188	Transcriptional regulator
AS97_RS38795	COG1940	carbohydrate kinase activity
AS97_RS38810	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AS97_RS38850	COG1136	(ABC) transporter
AS97_RS38850	COG0577	efflux transmembrane transporter activity
AS97_RS38855	COG2226	methyltransferase
AS97_RS38860	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AS97_RS38865	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AS97_RS38870	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AS97_RS38875	COG0156	8-amino-7-oxononanoate synthase activity
AS97_RS38900	COG0791	NLP P60 protein
AS97_RS38900	COG0741	lytic transglycosylase activity
AS97_RS38910	COG0740	serine-type endopeptidase activity
AS97_RS38920	COG2234	aminopeptidase activity
AS97_RS38920	COG4935	Belongs to the peptidase S8 family
AS97_RS38925	COG0831	urea catabolic process
AS97_RS38930	COG0832	Belongs to the urease beta subunit family
AS97_RS38935	COG0804	urea catabolic process
AS97_RS38940	COG0830	nickel cation binding
AS97_RS38945	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AS97_RS38950	COG0829	nickel cation binding
AS97_RS39005	COG0205	6-phosphofructokinase activity
AS97_RS39010	COG3442	glutamine amidotransferase
AS97_RS39020	COG0242	peptide deformylase activity
AS97_RS39030	COG1960	acyl-CoA dehydrogenase activity
AS97_RS39035	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AS97_RS39080	COG0702	epimerase
AS97_RS39085	COG3631	Ketosteroid isomerase-related protein
AS97_RS39090	COG1309	transcriptional regulator
AS97_RS39105	COG0252	asparaginase activity
AS97_RS39120	COG1793	dna ligase
AS97_RS39130	COG1191	sigma factor activity
AS97_RS39145	COG1132	(ABC) transporter
AS97_RS39150	COG1132	(ABC) transporter
AS97_RS39155	COG1349	DNA-binding transcription factor activity
AS97_RS39160	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AS97_RS39175	COG0747	negative chemotaxis
AS97_RS39180	COG0601	transmembrane transport
AS97_RS39185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AS97_RS39195	COG4608	Belongs to the ABC transporter superfamily
AS97_RS39200	COG0667	Aldo Keto reductase
AS97_RS39210	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS39270	COG3629	intracellular signal transduction
AS97_RS39270	COG3903	Transcriptional regulator
AS97_RS39275	COG1595	DNA-templated transcription, initiation
AS97_RS39295	COG0395	ABC-type sugar transport system, permease component
AS97_RS39300	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AS97_RS39335	COG0242	peptide deformylase activity
AS97_RS39400	COG1063	alcohol dehydrogenase
AS97_RS39425	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AS97_RS39430	COG0277	FAD linked oxidase domain protein
AS97_RS39440	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AS97_RS39520	COG1126	abc transporter atp-binding protein
AS97_RS39525	COG0765	amino acid transport
AS97_RS39575	COG2186	Transcriptional regulator
AS97_RS39600	COG0514	ATP-dependent DNA helicase (RecQ)
AS97_RS39615	COG1914	H( )-stimulated, divalent metal cation uptake system
AS97_RS39620	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AS97_RS39635	COG1063	alcohol dehydrogenase
AS97_RS39640	COG0395	ABC-type sugar transport system, permease component
AS97_RS39660	COG1486	melibiose metabolic process
AS97_RS39670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AS97_RS39675	COG1653	transport
AS97_RS39680	COG1175	transmembrane transport
AS97_RS39685	COG0395	ABC-type sugar transport system, permease component
AS97_RS39770	COG2353	YceI-like domain
AS97_RS39800	COG0667	Aldo Keto reductase
AS97_RS39870	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AS97_RS39915	COG0386	Belongs to the glutathione peroxidase family
AS97_RS39925	COG1595	DNA-templated transcription, initiation
AS97_RS39965	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AS97_RS39970	COG0583	DNA-binding transcription factor activity
AS97_RS39975	COG2851	Citrate transporter
AS97_RS39980	COG1064	alcohol dehydrogenase
AS97_RS39985	COG3537	Alpha-1,2-mannosidase
AS97_RS39990	COG4221	oxidoreductase activity
AS97_RS40025	COG0174	glutamine synthetase
AS97_RS40035	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AS97_RS40050	COG2133	pyrroloquinoline quinone binding
AS97_RS40065	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AS97_RS40070	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
AS97_RS40090	COG0438	transferase activity, transferring glycosyl groups
AS97_RS40095	COG0745	RESPONSE REGULATOR receiver
AS97_RS40100	COG2205	protein histidine kinase activity
AS97_RS40100	COG2972	Histidine kinase
AS97_RS40125	COG0477	Major facilitator Superfamily
AS97_RS40130	COG1733	regulation of RNA biosynthetic process
AS97_RS40145	COG0671	phosphoesterase, PA-phosphatase related
AS97_RS40160	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AS97_RS40210	COG0110	maltose O-acetyltransferase activity
AS97_RS40225	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
AS97_RS40295	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AS97_RS40360	COG1131	(ABC) transporter
AS97_RS40370	COG3851	Histidine kinase
AS97_RS40375	COG2197	response regulator
AS97_RS40385	COG0667	Aldo Keto reductase
AS97_RS40405	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AS97_RS40420	COG3959	Transketolase, thiamine diphosphate binding domain
AS97_RS40435	COG3360	Dodecin
AS97_RS40445	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AS97_RS40470	COG1024	Enoyl-CoA hydratase
AS97_RS40475	COG1960	acyl-CoA dehydrogenase activity
AS97_RS40490	COG1309	transcriptional regulator
AS97_RS40535	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AS97_RS40550	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AS97_RS40560	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AS97_RS40565	COG2205	protein histidine kinase activity
AS97_RS40570	COG0745	RESPONSE REGULATOR receiver
AS97_RS40595	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AS97_RS40620	COG0191	fructose-bisphosphate aldolase activity
AS97_RS40625	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AS97_RS40630	COG1349	DNA-binding transcription factor activity
AS97_RS40635	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AS97_RS40665	COG2182	Extracellular solute-binding protein
AS97_RS40670	COG1175	transmembrane transport
AS97_RS40675	COG0395	ABC-type sugar transport system, permease component
AS97_RS40680	COG2723	6-phospho-beta-galactosidase activity
AS97_RS40705	COG1796	DNA polymerase
AS97_RS40705	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AS97_RS40715	COG3250	beta-galactosidase activity
AS97_RS40735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS97_RS40745	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS40760	COG1472	Belongs to the glycosyl hydrolase 3 family
AS97_RS40770	COG1802	Transcriptional regulator
AS97_RS40775	COG1012	belongs to the aldehyde dehydrogenase family
AS97_RS40780	COG0596	Alpha beta hydrolase
AS97_RS40795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS97_RS40800	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AS97_RS40815	COG1522	sequence-specific DNA binding
AS97_RS40825	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AS97_RS40845	COG0443	Heat shock 70 kDa protein
AS97_RS40860	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AS97_RS40885	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AS97_RS40905	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AS97_RS40910	COG1834	amidinotransferase
AS97_RS40930	COG0673	inositol 2-dehydrogenase activity
AS97_RS40940	COG3290	protein histidine kinase activity
AS97_RS40950	COG2207	Transcriptional regulator
AS97_RS40955	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS40980	COG0189	ligase activity
AS97_RS40985	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AS97_RS40985	COG1522	sequence-specific DNA binding
AS97_RS40990	COG2313	pseudouridylate synthase activity
AS97_RS40995	COG0384	phenazine biosynthesis protein PhzF
AS97_RS41025	COG0747	negative chemotaxis
AS97_RS41035	COG1012	belongs to the aldehyde dehydrogenase family
AS97_RS41045	COG1595	DNA-templated transcription, initiation
AS97_RS41055	COG0542	response to heat
AS97_RS41070	COG2936	dipeptidyl-peptidase activity
AS97_RS41080	COG3629	intracellular signal transduction
AS97_RS41100	COG0604	alcohol dehydrogenase
AS97_RS41100	COG3321	synthase
AS97_RS41105	COG0604	alcohol dehydrogenase
AS97_RS41105	COG3321	synthase
AS97_RS41110	COG3321	synthase
AS97_RS41110	COG0604	alcohol dehydrogenase
AS97_RS41120	COG0596	Alpha beta hydrolase
AS97_RS41120	COG2945	thiolester hydrolase activity
AS97_RS41185	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AS97_RS41255	COG1215	transferase activity, transferring glycosyl groups
AS97_RS41275	COG1309	transcriptional regulator
AS97_RS41280	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AS97_RS41285	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AS97_RS41290	COG2080	2 iron, 2 sulfur cluster binding
AS97_RS41305	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AS97_RS41365	COG0477	Major facilitator Superfamily
AS97_RS41385	COG0006	proline dipeptidase activity
AS97_RS41400	COG3012	SEC-C Motif Domain Protein
AS97_RS41405	COG1063	alcohol dehydrogenase
AS97_RS41410	COG2271	Major facilitator Superfamily
AS97_RS41520	COG0789	Transcriptional regulator
AS97_RS41535	COG0464	growth
AS97_RS41570	COG0437	4 iron, 4 sulfur cluster binding
AS97_RS41575	COG3383	formate dehydrogenase (NAD+) activity
AS97_RS41575	COG0243	molybdopterin cofactor binding
AS97_RS41600	COG1309	transcriptional regulator
AS97_RS41640	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AS97_RS41680	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AS97_RS41690	COG2340	Cysteine-rich secretory protein family
AS97_RS41705	COG0531	amino acid
AS97_RS41715	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AS97_RS41740	COG3290	protein histidine kinase activity
AS97_RS41760	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
AS97_RS41770	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AS97_RS41775	COG3572	ergothioneine biosynthetic process
AS97_RS41785	COG1960	acyl-CoA dehydrogenase activity
AS97_RS41790	COG1960	acyl-CoA dehydrogenase activity
AS97_RS41810	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AS97_RS41815	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AS97_RS41835	COG1070	Carbohydrate kinase
AS97_RS41845	COG4677	pectinesterase activity
AS97_RS41855	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS41860	COG1309	transcriptional regulator
AS97_RS41865	COG1902	pentaerythritol trinitrate reductase activity
AS97_RS41875	COG0800	Aldolase
AS97_RS41885	COG1609	Transcriptional regulator
AS97_RS41900	COG0673	inositol 2-dehydrogenase activity
AS97_RS41905	COG0477	Major facilitator Superfamily
AS97_RS41910	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS41960	COG2267	carboxylic ester hydrolase activity
AS97_RS41985	COG2018	Roadblock/LC7 domain
AS97_RS41995	COG1946	Acyl-CoA thioesterase
AS97_RS42010	COG1132	(ABC) transporter
AS97_RS42015	COG1132	(ABC) transporter
AS97_RS42030	COG1132	(ABC) transporter
AS97_RS42055	COG3321	synthase
AS97_RS42055	COG0604	alcohol dehydrogenase
AS97_RS42065	COG0604	alcohol dehydrogenase
AS97_RS42065	COG3321	synthase
AS97_RS42095	COG0604	alcohol dehydrogenase
AS97_RS42095	COG3321	synthase
AS97_RS42100	COG0318	PFAM AMP-dependent synthetase and ligase
AS97_RS42110	COG1309	transcriptional regulator
AS97_RS42120	COG1733	regulation of RNA biosynthetic process
AS97_RS42140	COG2391	methyltransferase activity
AS97_RS42155	COG2318	DinB family
AS97_RS42170	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AS97_RS42175	COG1113	amino acid transport
AS97_RS42180	COG2207	Transcriptional regulator
AS97_RS42180	COG3708	Transcriptional regulator
AS97_RS42200	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AS97_RS42205	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AS97_RS42210	COG2080	2 iron, 2 sulfur cluster binding
AS97_RS42240	COG4608	Belongs to the ABC transporter superfamily
AS97_RS42245	COG0444	Belongs to the ABC transporter superfamily
AS97_RS42250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AS97_RS42255	COG0601	transmembrane transport
AS97_RS42260	COG4166	transmembrane transport
AS97_RS42265	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AS97_RS42300	COG2188	Transcriptional regulator
AS97_RS42305	COG1397	ADP-ribosylglycohydrolase
AS97_RS42350	COG0367	asparagine synthase
AS97_RS42375	COG0492	ferredoxin-NADP+ reductase activity
AS97_RS42380	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
AS97_RS42435	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AS97_RS42465	COG0402	S-adenosylhomocysteine deaminase activity
AS97_RS42470	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AS97_RS42505	COG1309	transcriptional regulator
AS97_RS42510	COG1960	acyl-CoA dehydrogenase activity
AS97_RS42530	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AS97_RS42545	COG0179	Fumarylacetoacetate (FAA) hydrolase
AS97_RS42555	COG0145	ligase activity
AS97_RS42570	COG2814	Major facilitator Superfamily
AS97_RS42575	COG0318	PFAM AMP-dependent synthetase and ligase
AS97_RS42590	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS42645	COG3622	Belongs to the hyi family
AS97_RS42660	COG0235	Class ii aldolase
AS97_RS42665	COG3395	kinase activity
AS97_RS42680	COG0477	Major facilitator Superfamily
AS97_RS42695	COG1113	amino acid transport
AS97_RS42715	COG3485	protocatechuate 3,4-dioxygenase
AS97_RS42725	COG1414	Transcriptional regulator
AS97_RS42735	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AS97_RS42740	COG4221	oxidoreductase activity
AS97_RS42760	COG1132	(ABC) transporter
AS97_RS42765	COG1132	(ABC) transporter
AS97_RS42810	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AS97_RS42815	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AS97_RS42850	COG3173	Aminoglycoside phosphotransferase
AS97_RS42855	COG4770	biotin carboxylase activity
AS97_RS42870	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AS97_RS42905	COG0765	amino acid transport
AS97_RS42910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AS97_RS42955	COG0667	Aldo Keto reductase
AS97_RS42975	COG0667	Aldo Keto reductase
AS97_RS42980	COG4948	Mandelate Racemase Muconate Lactonizing
AS97_RS42985	COG3547	Transposase (IS116 IS110 IS902 family)
AS97_RS42990	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AS97_RS43010	COG2814	Major facilitator Superfamily
AS97_RS43025	COG0673	inositol 2-dehydrogenase activity
AS97_RS43040	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AS97_RS43040	COG1796	DNA polymerase
AS97_RS43070	COG0697	spore germination
AS97_RS43095	COG1454	alcohol dehydrogenase
AS97_RS43105	COG1012	belongs to the aldehyde dehydrogenase family
AS97_RS43110	COG4948	Mandelate Racemase Muconate Lactonizing
AS97_RS43130	COG0477	Major facilitator Superfamily
AS97_RS43190	COG0583	DNA-binding transcription factor activity
AS97_RS43200	COG1846	Transcriptional regulator
AS97_RS43200	COG1940	carbohydrate kinase activity
AS97_RS43205	COG3345	alpha-galactosidase
AS97_RS43215	COG3401	FG-GAP repeat protein
AS97_RS43215	COG2755	lipolytic protein G-D-S-L family
AS97_RS43235	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS43250	COG0745	RESPONSE REGULATOR receiver
AS97_RS43260	COG0583	DNA-binding transcription factor activity
AS97_RS43285	COG0318	PFAM AMP-dependent synthetase and ligase
AS97_RS43290	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AS97_RS43300	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AS97_RS43310	COG1021	2,3-dihydroxybenzoate-AMP ligase
AS97_RS43355	COG1609	Transcriptional regulator
AS97_RS43370	COG3486	L-lysine 6-monooxygenase (NADPH) activity
AS97_RS43375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS97_RS43380	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS97_RS43385	COG1120	ATPase activity
AS97_RS43390	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AS97_RS43395	COG1132	(ABC) transporter
AS97_RS43405	COG1132	(ABC) transporter
AS97_RS43410	COG2382	esterase
AS97_RS43445	COG1233	COG1233 Phytoene dehydrogenase and related
AS97_RS43470	COG3458	cephalosporin-C deacetylase activity
AS97_RS43485	COG0745	RESPONSE REGULATOR receiver
AS97_RS43530	COG3250	beta-galactosidase activity
AS97_RS43535	COG0395	ABC-type sugar transport system, permease component
AS97_RS43540	COG1175	transmembrane transport
AS97_RS43550	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AS97_RS43560	COG1486	melibiose metabolic process
AS97_RS43675	COG2197	response regulator
AS97_RS43695	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS43765	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS97_RS43785	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AS97_RS43790	COG0601	transmembrane transport
AS97_RS43805	COG0477	Major facilitator Superfamily
AS97_RS43810	COG1942	4-Oxalocrotonate Tautomerase
AS97_RS43825	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AS97_RS43835	COG0477	Major facilitator Superfamily
AS97_RS43840	COG1414	Transcriptional regulator
AS97_RS43890	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS43900	COG4569	acetaldehyde dehydrogenase (acetylating) activity
AS97_RS43905	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AS97_RS43955	COG0789	Transcriptional regulator
AS97_RS43970	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS43975	COG1960	acyl-CoA dehydrogenase activity
AS97_RS43980	COG1960	acyl-CoA dehydrogenase activity
AS97_RS43985	COG1024	Enoyl-CoA hydratase
AS97_RS43990	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS43995	COG1309	transcriptional regulator
AS97_RS44000	COG0183	Belongs to the thiolase family
AS97_RS44020	COG1024	Enoyl-CoA hydratase
AS97_RS44030	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS44040	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS44060	COG4989	oxidoreductase activity
AS97_RS44080	COG1064	alcohol dehydrogenase
AS97_RS44130	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AS97_RS44165	COG3321	synthase
AS97_RS44165	COG0604	alcohol dehydrogenase
AS97_RS44180	COG1252	NADH dehydrogenase
AS97_RS44225	COG0583	DNA-binding transcription factor activity
AS97_RS44245	COG1136	(ABC) transporter
AS97_RS44255	COG1609	Transcriptional regulator
AS97_RS44260	COG1653	transport
AS97_RS44265	COG1175	transmembrane transport
AS97_RS44275	COG1472	Belongs to the glycosyl hydrolase 3 family
AS97_RS44285	COG0129	dihydroxy-acid dehydratase activity
AS97_RS44300	COG1980	fructose-bisphosphate aldolase activity
AS97_RS44315	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AS97_RS44335	COG3507	Belongs to the glycosyl hydrolase 43 family
AS97_RS44340	COG3345	alpha-galactosidase
AS97_RS44360	COG3250	beta-galactosidase activity
AS97_RS44365	COG3509	depolymerase
AS97_RS44375	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AS97_RS44395	COG3693	PFAM glycoside hydrolase, family 10
AS97_RS44415	COG1802	Transcriptional regulator
AS97_RS44420	COG0179	Fumarylacetoacetate (FAA) hydrolase
AS97_RS44430	COG2814	Major facilitator Superfamily
AS97_RS44435	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AS97_RS44445	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AS97_RS44485	COG1396	sequence-specific DNA binding
AS97_RS44515	COG1172	Belongs to the binding-protein-dependent transport system permease family
AS97_RS44520	COG1129	ABC transporter
AS97_RS44535	COG0434	BtpA family
AS97_RS44540	COG1609	Transcriptional regulator
AS97_RS44555	COG1017	nitric oxide dioxygenase activity
AS97_RS44555	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AS97_RS44575	COG2423	ornithine cyclodeaminase activity
AS97_RS44580	COG3938	Belongs to the proline racemase family
AS97_RS44595	COG2318	DinB family
AS97_RS44660	COG2197	response regulator
AS97_RS44670	COG2409	Drug exporters of the RND superfamily
AS97_RS44715	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AS97_RS44725	COG2267	carboxylic ester hydrolase activity
AS97_RS44740	COG0300	oxidoreductase activity
AS97_RS44745	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AS97_RS44755	COG1476	TRANSCRIPTIONal
AS97_RS44760	COG2171	N-acyltransferase activity
AS97_RS44765	COG4266	Belongs to the allantoicase family
AS97_RS44770	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AS97_RS44780	COG1953	Uracil, thiamine, allantoin
AS97_RS44790	COG1414	Transcriptional regulator
AS97_RS44800	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AS97_RS44810	COG3622	Belongs to the hyi family
AS97_RS44815	COG2084	Dehydrogenase
AS97_RS44820	COG3960	tartronate-semialdehyde synthase activity
AS97_RS44825	COG1929	Belongs to the glycerate kinase type-1 family
AS97_RS44845	COG1309	transcriptional regulator
AS97_RS44850	COG1960	acyl-CoA dehydrogenase activity
AS97_RS44920	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AS97_RS44945	COG0477	Major facilitator Superfamily
AS97_RS44965	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AS97_RS45065	COG0488	(ABC) transporter
AS97_RS45070	COG0488	(ABC) transporter
AS97_RS45105	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS45135	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AS97_RS45185	COG0701	Predicted permease
AS97_RS45215	COG3547	Transposase (IS116 IS110 IS902 family)
AS97_RS45245	COG0492	ferredoxin-NADP+ reductase activity
AS97_RS45250	COG2814	Major facilitator Superfamily
AS97_RS45320	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AS97_RS45335	COG0242	peptide deformylase activity
AS97_RS45410	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS45435	COG0596	Alpha beta hydrolase
AS97_RS45555	COG4598	ABC transporter
AS97_RS45580	COG2124	cytochrome p450
AS97_RS45585	COG1960	acyl-CoA dehydrogenase activity
AS97_RS45590	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AS97_RS45595	COG1960	acyl-CoA dehydrogenase activity
AS97_RS45600	COG0477	Major facilitator Superfamily
AS97_RS45605	COG0583	DNA-binding transcription factor activity
AS97_RS45640	COG0604	alcohol dehydrogenase
AS97_RS45640	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS45640	COG3321	synthase
AS97_RS45695	COG3547	Transposase (IS116 IS110 IS902 family)
AS97_RS45700	COG2755	lipolytic protein G-D-S-L family
AS97_RS45730	COG0829	nickel cation binding
AS97_RS45735	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AS97_RS45745	COG0804	urea catabolic process
AS97_RS45750	COG0832	Belongs to the urease beta subunit family
AS97_RS45800	COG3547	Transposase (IS116 IS110 IS902 family)
AS97_RS45810	COG4124	Belongs to the glycosyl hydrolase 26 family
AS97_RS45845	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AS97_RS45855	COG0463	Glycosyl transferase, family 2
AS97_RS45870	COG4172	Belongs to the ABC transporter superfamily
AS97_RS45880	COG0601	transmembrane transport
AS97_RS45890	COG1940	carbohydrate kinase activity
AS97_RS45910	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AS97_RS45915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS97_RS45930	COG1012	belongs to the aldehyde dehydrogenase family
AS97_RS45935	COG0596	Alpha beta hydrolase
AS97_RS45965	COG1802	Transcriptional regulator
AS97_RS45975	COG2801	Transposase and inactivated derivatives
AS97_RS45990	COG0477	Major facilitator Superfamily
AS97_RS45995	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS46000	COG1414	Transcriptional regulator
AS97_RS46010	COG0179	Fumarylacetoacetate (FAA) hydrolase
AS97_RS46015	COG0179	Fumarylacetoacetate (FAA) hydrolase
AS97_RS46020	COG1028	Short-chain dehydrogenase reductase Sdr
AS97_RS46080	COG2267	carboxylic ester hydrolase activity
AS97_RS46100	COG3473	Maleate cis-trans isomerase
AS97_RS46115	COG1309	transcriptional regulator
AS97_RS46120	COG1012	belongs to the aldehyde dehydrogenase family
AS97_RS46155	COG1012	belongs to the aldehyde dehydrogenase family
AS97_RS46165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS97_RS46170	COG2188	Transcriptional regulator
AS97_RS46175	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AS97_RS46180	COG2814	Major facilitator Superfamily
AS97_RS46235	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AS97_RS46260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS97_RS46280	COG2226	methyltransferase
AS97_RS46290	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AS97_RS46295	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AS97_RS46340	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AS97_RS46435	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP