locus-tag	class	description
OIM89_RS00005	COG1472	Belongs to the glycosyl hydrolase 3 family
OIM89_RS00010	COG1874	Beta-galactosidase
OIM89_RS00015	COG1609	Transcriptional regulator
OIM89_RS00020	COG0395	ABC-type sugar transport system, permease component
OIM89_RS00025	COG1175	transmembrane transport
OIM89_RS00045	COG1028	Short-chain dehydrogenase reductase Sdr
OIM89_RS00050	COG0477	Major facilitator Superfamily
OIM89_RS00075	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OIM89_RS00080	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
OIM89_RS00085	COG2080	2 iron, 2 sulfur cluster binding
OIM89_RS00095	COG2197	response regulator
OIM89_RS00100	COG4585	Histidine kinase
OIM89_RS00105	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
OIM89_RS00125	COG0477	Major facilitator Superfamily
OIM89_RS00180	COG0446	pyridine nucleotide-disulphide oxidoreductase
OIM89_RS00180	COG0404	The glycine cleavage system catalyzes the degradation of glycine
OIM89_RS00230	COG4608	Belongs to the ABC transporter superfamily
OIM89_RS00235	COG0444	Belongs to the ABC transporter superfamily
OIM89_RS00240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OIM89_RS00245	COG0601	transmembrane transport
OIM89_RS00250	COG0747	negative chemotaxis
OIM89_RS00260	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OIM89_RS00290	COG1793	dna ligase
OIM89_RS00325	COG0277	FAD linked oxidase domain protein
OIM89_RS00370	COG0318	PFAM AMP-dependent synthetase and ligase
OIM89_RS00375	COG0589	response to stress
OIM89_RS00380	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OIM89_RS00385	COG2813	Specifically methylates the guanine in position
OIM89_RS00395	COG2356	endonuclease I
OIM89_RS00425	COG2084	Dehydrogenase
OIM89_RS00460	COG1007	ATP synthesis coupled electron transport
OIM89_RS00465	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OIM89_RS00470	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OIM89_RS00475	COG0713	ATP synthesis coupled electron transport
OIM89_RS00485	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
OIM89_RS00495	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OIM89_RS00505	COG4733	cellulase activity
OIM89_RS00505	COG5297	Belongs to the glycosyl hydrolase family 6
OIM89_RS00515	COG1902	pentaerythritol trinitrate reductase activity
OIM89_RS00515	COG0446	pyridine nucleotide-disulphide oxidoreductase
OIM89_RS00525	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OIM89_RS00560	COG0475	glutathione-regulated potassium exporter activity
OIM89_RS00580	COG2197	response regulator
OIM89_RS00590	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OIM89_RS00605	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OIM89_RS00615	COG0640	Transcriptional regulator
OIM89_RS00630	COG0531	amino acid
OIM89_RS00650	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OIM89_RS00655	COG2192	nodulation
OIM89_RS00665	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
OIM89_RS00670	COG0859	PFAM glycosyl transferase family 9
OIM89_RS00680	COG0297	glycogen (starch) synthase activity
OIM89_RS00685	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
OIM89_RS00690	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
OIM89_RS00690	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
OIM89_RS00695	COG0859	PFAM glycosyl transferase family 9
OIM89_RS00720	COG1028	Short-chain dehydrogenase reductase Sdr
OIM89_RS00725	COG1482	cell wall glycoprotein biosynthetic process
OIM89_RS00730	COG0477	Major facilitator Superfamily
OIM89_RS00745	COG0328	RNA-DNA hybrid ribonuclease activity
OIM89_RS00750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OIM89_RS00755	COG0431	NADPH-dependent FMN reductase
OIM89_RS00785	COG1595	DNA-templated transcription, initiation
OIM89_RS00810	COG0667	Aldo Keto reductase
OIM89_RS00835	COG0726	polysaccharide deacetylase
OIM89_RS00845	COG1562	ergosterol biosynthetic process
OIM89_RS00850	COG1131	(ABC) transporter
OIM89_RS00870	COG0326	Molecular chaperone. Has ATPase activity
OIM89_RS00890	COG0702	epimerase
OIM89_RS00900	COG0346	lactoylglutathione lyase activity
OIM89_RS00905	COG0640	Transcriptional regulator
OIM89_RS00920	COG1120	ATPase activity
OIM89_RS00940	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OIM89_RS00960	COG1250	3-hydroxyacyl-CoA dehydrogenase
OIM89_RS00965	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OIM89_RS00985	COG1349	DNA-binding transcription factor activity
OIM89_RS00995	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OIM89_RS00995	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OIM89_RS00995	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
OIM89_RS01000	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OIM89_RS01000	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
OIM89_RS01005	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OIM89_RS01020	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OIM89_RS01040	COG2226	methyltransferase
OIM89_RS01080	COG1028	Short-chain dehydrogenase reductase Sdr
OIM89_RS01095	COG0513	Belongs to the DEAD box helicase family
OIM89_RS01105	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
OIM89_RS01120	COG3217	Mosc domain protein beta barrel domain protein
OIM89_RS01120	COG0633	Ferredoxin
OIM89_RS01140	COG1349	DNA-binding transcription factor activity
OIM89_RS01160	COG1940	carbohydrate kinase activity
OIM89_RS01170	COG2223	nitrite transmembrane transporter activity
OIM89_RS01185	COG2197	response regulator
OIM89_RS01190	COG0445	tRNA wobble uridine modification
OIM89_RS01200	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OIM89_RS01215	COG1609	Transcriptional regulator
OIM89_RS01225	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
OIM89_RS01270	COG0584	glycerophosphoryl diester phosphodiesterase
OIM89_RS01285	COG1846	Transcriptional regulator
OIM89_RS01305	COG0671	phosphoesterase, PA-phosphatase related
OIM89_RS01335	COG2233	PERMEase
OIM89_RS01340	COG0640	Transcriptional regulator
OIM89_RS01345	COG1902	pentaerythritol trinitrate reductase activity
OIM89_RS01370	COG0586	Pfam SNARE associated Golgi protein
OIM89_RS01375	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
OIM89_RS01390	COG2706	6-phosphogluconolactonase activity
OIM89_RS01400	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
OIM89_RS01405	COG0071	Belongs to the small heat shock protein (HSP20) family
OIM89_RS01445	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OIM89_RS01465	COG2814	Major facilitator Superfamily
OIM89_RS01495	COG1309	transcriptional regulator
OIM89_RS01510	COG1472	Belongs to the glycosyl hydrolase 3 family
OIM89_RS01515	COG0395	ABC-type sugar transport system, permease component
OIM89_RS01520	COG1175	transmembrane transport
OIM89_RS01530	COG1609	Transcriptional regulator
OIM89_RS01555	COG0432	Pfam Uncharacterised protein family UPF0047
OIM89_RS01560	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OIM89_RS01565	COG1116	anion transmembrane transporter activity
OIM89_RS01575	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OIM89_RS01585	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OIM89_RS01590	COG1132	(ABC) transporter
OIM89_RS01610	COG1132	(ABC) transporter
OIM89_RS01615	COG1132	(ABC) transporter
OIM89_RS01630	COG1946	Acyl-CoA thioesterase
OIM89_RS01645	COG2018	Roadblock/LC7 domain
OIM89_RS01690	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
OIM89_RS01715	COG1070	Carbohydrate kinase
OIM89_RS01725	COG2124	cytochrome p450
OIM89_RS01730	COG2130	NADP-dependent
OIM89_RS01735	COG1233	COG1233 Phytoene dehydrogenase and related
OIM89_RS01810	COG0477	Major facilitator Superfamily
OIM89_RS01815	COG0183	Belongs to the thiolase family
OIM89_RS01820	COG0583	DNA-binding transcription factor activity
OIM89_RS01825	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OIM89_RS01830	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OIM89_RS01835	COG1250	3-hydroxyacyl-CoA dehydrogenase
OIM89_RS01840	COG1960	acyl-CoA dehydrogenase activity
OIM89_RS01845	COG2391	methyltransferase activity
OIM89_RS01890	COG1396	sequence-specific DNA binding
OIM89_RS01895	COG0740	serine-type endopeptidase activity
OIM89_RS01900	COG0740	serine-type endopeptidase activity
OIM89_RS01950	COG3959	Transketolase, thiamine diphosphate binding domain
OIM89_RS01955	COG3958	Transketolase
OIM89_RS02030	COG2755	lipolytic protein G-D-S-L family
OIM89_RS02035	COG2365	Tyrosine phosphatase family
OIM89_RS02065	COG1657	PFAM Prenyltransferase squalene oxidase
OIM89_RS02075	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
OIM89_RS02085	COG1562	ergosterol biosynthetic process
OIM89_RS02090	COG1134	teichoic acid transport
OIM89_RS02090	COG1388	LysM domain
OIM89_RS02115	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
OIM89_RS02130	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
OIM89_RS02140	COG1162	GTPase activity
OIM89_RS02155	COG1024	Enoyl-CoA hydratase
OIM89_RS02180	COG1802	Transcriptional regulator
OIM89_RS02185	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
OIM89_RS02190	COG0402	S-adenosylhomocysteine deaminase activity
OIM89_RS02210	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OIM89_RS02215	COG0789	Transcriptional regulator
OIM89_RS02220	COG1024	Enoyl-CoA hydratase
OIM89_RS02220	COG1250	3-hydroxyacyl-CoA dehydrogenase
OIM89_RS02225	COG0183	Belongs to the thiolase family
OIM89_RS02230	COG1960	acyl-CoA dehydrogenase activity
OIM89_RS02235	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OIM89_RS02245	COG1515	deoxyribonuclease V activity
OIM89_RS02265	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OIM89_RS02275	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OIM89_RS02275	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OIM89_RS02305	COG2197	response regulator
OIM89_RS02320	COG0438	transferase activity, transferring glycosyl groups
OIM89_RS02355	COG0254	rRNA binding
OIM89_RS02365	COG1793	dna ligase
OIM89_RS02370	COG1024	Enoyl-CoA hydratase
OIM89_RS02405	COG0789	Transcriptional regulator
OIM89_RS02430	COG4249	Peptidase C14 caspase catalytic subunit p20
OIM89_RS02430	COG2319	Wd-40 repeat
OIM89_RS02460	COG2274	protein secretion by the type I secretion system
OIM89_RS02465	COG1846	Transcriptional regulator
OIM89_RS02500	COG1028	Short-chain dehydrogenase reductase Sdr
OIM89_RS02525	COG1012	belongs to the aldehyde dehydrogenase family
OIM89_RS02530	COG2080	2 iron, 2 sulfur cluster binding
OIM89_RS02545	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OIM89_RS02550	COG2814	Major facilitator Superfamily
OIM89_RS02555	COG2259	Doxx family
OIM89_RS02565	COG1869	D-ribose catabolic process
OIM89_RS02570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OIM89_RS02580	COG1129	ABC transporter
OIM89_RS02585	COG1609	Transcriptional regulator
OIM89_RS02605	COG1295	ribonuclease BN
OIM89_RS02670	COG0673	inositol 2-dehydrogenase activity
OIM89_RS02680	COG1172	Belongs to the binding-protein-dependent transport system permease family
OIM89_RS02685	COG1129	ABC transporter
OIM89_RS02690	COG1940	carbohydrate kinase activity
OIM89_RS02695	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OIM89_RS02710	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OIM89_RS02720	COG0583	DNA-binding transcription factor activity
OIM89_RS02725	COG1115	amino acid carrier protein
OIM89_RS02750	COG2154	pterin-4-alpha-carbinolamine dehydratase
OIM89_RS02780	COG1140	nitrate reductase beta subunit
OIM89_RS02795	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
OIM89_RS02845	COG0693	protein deglycase activity
OIM89_RS02855	COG1597	lipid kinase activity
OIM89_RS02860	COG2226	methyltransferase
OIM89_RS02875	COG3226	Transcriptional regulator
OIM89_RS02890	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OIM89_RS02905	COG1619	proteins homologs of microcin C7 resistance protein MccF
OIM89_RS02915	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OIM89_RS02955	COG0596	Alpha beta hydrolase
OIM89_RS02975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OIM89_RS02980	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OIM89_RS02985	COG1120	ATPase activity
OIM89_RS02990	COG1250	3-hydroxyacyl-CoA dehydrogenase
OIM89_RS03000	COG0604	alcohol dehydrogenase
OIM89_RS03005	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OIM89_RS03005	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OIM89_RS03010	COG2301	Belongs to the HpcH HpaI aldolase family
OIM89_RS03025	COG0688	phosphatidylethanolamine metabolic process
OIM89_RS03035	COG1929	Belongs to the glycerate kinase type-1 family
OIM89_RS03040	COG0488	(ABC) transporter
OIM89_RS03055	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
OIM89_RS03060	COG0702	epimerase
OIM89_RS03075	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
OIM89_RS03100	COG0159	tryptophan synthase activity
OIM89_RS03115	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
OIM89_RS03130	COG0483	inositol monophosphate 1-phosphatase activity
OIM89_RS03140	COG0095	Lipoate-protein ligase
OIM89_RS03160	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
OIM89_RS03185	COG0405	Gamma-glutamyltransferase
OIM89_RS03215	COG0765	amino acid transport
OIM89_RS03220	COG0765	amino acid transport
OIM89_RS03225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OIM89_RS03230	COG1126	abc transporter atp-binding protein
OIM89_RS03260	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OIM89_RS03270	COG1960	acyl-CoA dehydrogenase activity
OIM89_RS03290	COG5183	chlorophyll binding
OIM89_RS03290	COG2133	pyrroloquinoline quinone binding
OIM89_RS03295	COG1132	(ABC) transporter
OIM89_RS03300	COG1132	(ABC) transporter
OIM89_RS03335	COG2197	response regulator
OIM89_RS03345	COG0464	growth
OIM89_RS03435	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
OIM89_RS03445	COG1940	carbohydrate kinase activity
OIM89_RS03455	COG1172	Belongs to the binding-protein-dependent transport system permease family
OIM89_RS03465	COG2188	Transcriptional regulator
OIM89_RS03470	COG0673	inositol 2-dehydrogenase activity
OIM89_RS03485	COG2197	response regulator
OIM89_RS03490	COG4585	Histidine kinase
OIM89_RS03505	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
OIM89_RS03510	COG1414	Transcriptional regulator
OIM89_RS03525	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OIM89_RS03530	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
OIM89_RS03535	COG2080	2 iron, 2 sulfur cluster binding
OIM89_RS03540	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
OIM89_RS03555	COG4941	Belongs to the sigma-70 factor family
OIM89_RS03560	COG3795	YCII-related domain
OIM89_RS03565	COG0723	plastoquinol--plastocyanin reductase activity
OIM89_RS03565	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OIM89_RS03570	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OIM89_RS03575	COG1621	beta-fructofuranosidase activity
OIM89_RS03580	COG1609	Transcriptional regulator
OIM89_RS03595	COG1609	Transcriptional regulator
OIM89_RS03645	COG2233	PERMEase
OIM89_RS03660	COG2351	hydroxyisourate hydrolase activity
OIM89_RS03680	COG3622	Belongs to the hyi family
OIM89_RS03685	COG2084	Dehydrogenase
OIM89_RS03690	COG0753	catalase activity
OIM89_RS03715	COG3960	tartronate-semialdehyde synthase activity
OIM89_RS03725	COG0318	PFAM AMP-dependent synthetase and ligase
OIM89_RS03730	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OIM89_RS03735	COG2197	response regulator
OIM89_RS03745	COG1309	transcriptional regulator
OIM89_RS03775	COG2252	PERMEase
OIM89_RS03780	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OIM89_RS03795	COG3835	regulator
OIM89_RS03800	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
OIM89_RS03810	COG1802	Transcriptional regulator
OIM89_RS03830	COG0028	Belongs to the TPP enzyme family
OIM89_RS03850	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OIM89_RS03855	COG1162	GTPase activity
OIM89_RS03860	COG2124	cytochrome p450
OIM89_RS03865	COG0028	Belongs to the TPP enzyme family
OIM89_RS03880	COG2365	Tyrosine phosphatase family
OIM89_RS03900	COG0583	DNA-binding transcription factor activity
OIM89_RS03920	COG1595	DNA-templated transcription, initiation
OIM89_RS03940	COG0702	epimerase
OIM89_RS03945	COG1846	Transcriptional regulator
OIM89_RS03950	COG2409	Drug exporters of the RND superfamily
OIM89_RS03960	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OIM89_RS03965	COG1120	ATPase activity
OIM89_RS03975	COG1131	(ABC) transporter
OIM89_RS03980	COG1309	transcriptional regulator
OIM89_RS03995	COG2255	four-way junction helicase activity
OIM89_RS04020	COG2040	homocysteine
OIM89_RS04040	COG1960	acyl-CoA dehydrogenase activity
OIM89_RS04045	COG0604	alcohol dehydrogenase
OIM89_RS04070	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OIM89_RS04080	COG0175	sulfate reduction
OIM89_RS04085	COG0529	Catalyzes the synthesis of activated sulfate
OIM89_RS04110	COG1116	anion transmembrane transporter activity
OIM89_RS04115	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OIM89_RS04130	COG0386	Belongs to the glutathione peroxidase family
OIM89_RS04135	COG1064	alcohol dehydrogenase
OIM89_RS04140	COG1309	transcriptional regulator
OIM89_RS04175	COG2176	DNA-directed DNA polymerase activity
OIM89_RS04175	COG5002	protein histidine kinase activity
OIM89_RS04240	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OIM89_RS04245	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OIM89_RS04265	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
OIM89_RS04295	COG3220	belongs to the UPF0276 family
OIM89_RS04305	COG3253	May function as heme-dependent peroxidase
OIM89_RS04310	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
OIM89_RS04320	COG0446	pyridine nucleotide-disulphide oxidoreductase
OIM89_RS04325	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
OIM89_RS04345	COG0183	Belongs to the thiolase family
OIM89_RS04350	COG1250	3-hydroxyacyl-CoA dehydrogenase
OIM89_RS04350	COG1024	Enoyl-CoA hydratase
OIM89_RS04370	COG0531	amino acid
OIM89_RS04375	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OIM89_RS04380	COG4214	carbohydrate transport
OIM89_RS04390	COG4213	ABC transporter substrate-binding protein
OIM89_RS04400	COG0395	ABC-type sugar transport system, permease component
OIM89_RS04405	COG1175	transmembrane transport
OIM89_RS04410	COG1653	transport
OIM89_RS04415	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
OIM89_RS04440	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OIM89_RS04450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OIM89_RS04485	COG2235	arginine
OIM89_RS04490	COG1320	monovalent cation:proton antiporter activity
OIM89_RS04505	COG0651	ATP synthesis coupled electron transport
OIM89_RS04510	COG1006	Multisubunit Na H antiporter MnhC subunit
OIM89_RS04515	COG2111	Na H antiporter
OIM89_RS04515	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OIM89_RS04525	COG2124	cytochrome p450
OIM89_RS04555	COG0531	amino acid
OIM89_RS04560	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OIM89_RS04565	COG2235	arginine
OIM89_RS04575	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
OIM89_RS04610	COG1799	cell septum assembly
OIM89_RS04620	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
OIM89_RS04635	COG1556	Lactate utilization protein
OIM89_RS04640	COG1139	Iron-sulfur cluster binding protein
OIM89_RS04645	COG0247	lactate metabolic process
OIM89_RS04650	COG1620	l-lactate permease
OIM89_RS04660	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
OIM89_RS04700	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OIM89_RS04710	COG0267	Belongs to the bacterial ribosomal protein bL33 family
OIM89_RS04720	COG0477	Major facilitator Superfamily
OIM89_RS04725	COG1120	ATPase activity
OIM89_RS04730	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OIM89_RS04735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OIM89_RS04745	COG1733	regulation of RNA biosynthetic process
OIM89_RS04775	COG1309	transcriptional regulator
OIM89_RS04790	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OIM89_RS04805	COG2936	dipeptidyl-peptidase activity
OIM89_RS04820	COG1028	Short-chain dehydrogenase reductase Sdr
OIM89_RS04825	COG3540	Alkaline phosphatase
OIM89_RS04835	COG2050	protein possibly involved in aromatic compounds catabolism
OIM89_RS04850	COG0789	Transcriptional regulator
OIM89_RS04860	COG0640	Transcriptional regulator
OIM89_RS04880	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OIM89_RS04945	COG0438	transferase activity, transferring glycosyl groups
OIM89_RS04950	COG3226	Transcriptional regulator
OIM89_RS04955	COG0738	Major facilitator superfamily
OIM89_RS04970	COG4213	ABC transporter substrate-binding protein
OIM89_RS04975	COG1172	Belongs to the binding-protein-dependent transport system permease family
OIM89_RS04980	COG1172	Belongs to the binding-protein-dependent transport system permease family
OIM89_RS04985	COG1129	ABC transporter
OIM89_RS04990	COG1846	Transcriptional regulator
OIM89_RS04990	COG1940	carbohydrate kinase activity
OIM89_RS04995	COG0252	asparaginase activity
OIM89_RS05005	COG1028	Short-chain dehydrogenase reductase Sdr
OIM89_RS05035	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
OIM89_RS05045	COG0473	3-isopropylmalate dehydrogenase activity
OIM89_RS05060	COG0656	L-ascorbic acid biosynthetic process
OIM89_RS05095	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
OIM89_RS05120	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
OIM89_RS05130	COG1127	ABC transporter
OIM89_RS05215	COG0395	ABC-type sugar transport system, permease component
OIM89_RS05220	COG1063	alcohol dehydrogenase
OIM89_RS05285	COG0438	transferase activity, transferring glycosyl groups
OIM89_RS05295	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OIM89_RS05300	COG0531	amino acid
OIM89_RS05310	COG0569	domain protein
OIM89_RS05340	COG1136	(ABC) transporter
OIM89_RS05360	COG0756	dUTP diphosphatase activity
OIM89_RS05385	COG2205	protein histidine kinase activity
OIM89_RS05390	COG0745	RESPONSE REGULATOR receiver
OIM89_RS05400	COG0483	inositol monophosphate 1-phosphatase activity
OIM89_RS05405	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
OIM89_RS05455	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OIM89_RS05470	COG1802	Transcriptional regulator
OIM89_RS05485	COG0612	Peptidase, M16
OIM89_RS05490	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OIM89_RS05500	COG0366	Alpha amylase catalytic
OIM89_RS05505	COG0395	ABC-type sugar transport system, permease component
OIM89_RS05510	COG1175	transmembrane transport
OIM89_RS05530	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OIM89_RS05565	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OIM89_RS05570	COG1802	Transcriptional regulator
OIM89_RS05610	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OIM89_RS05625	COG0588	phosphoglycerate mutase activity
OIM89_RS05650	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OIM89_RS05655	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
OIM89_RS05660	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OIM89_RS05700	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OIM89_RS05710	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OIM89_RS05715	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
OIM89_RS05725	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
OIM89_RS05745	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OIM89_RS05750	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
OIM89_RS05755	COG2205	protein histidine kinase activity
OIM89_RS05765	COG1126	abc transporter atp-binding protein
OIM89_RS05770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OIM89_RS05775	COG0765	amino acid transport
OIM89_RS05780	COG0765	amino acid transport
OIM89_RS05785	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OIM89_RS05795	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OIM89_RS05800	COG2137	regulation of response to DNA damage stimulus
OIM89_RS05805	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
OIM89_RS05840	COG0628	permease
OIM89_RS05865	COG1201	RNA secondary structure unwinding
OIM89_RS05870	COG0596	Alpha beta hydrolase
OIM89_RS05890	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
OIM89_RS05900	COG0783	Belongs to the Dps family
OIM89_RS05905	COG1396	sequence-specific DNA binding
OIM89_RS05910	COG1058	Belongs to the CinA family
OIM89_RS05910	COG1546	Belongs to the CinA family
OIM89_RS05920	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OIM89_RS05930	COG1674	ftsk spoiiie
OIM89_RS05940	COG3850	Histidine kinase
OIM89_RS05940	COG4999	Histidine kinase
OIM89_RS05940	COG2205	protein histidine kinase activity
OIM89_RS05940	COG3437	response regulator, receiver
OIM89_RS05945	COG2208	phosphoserine phosphatase activity
OIM89_RS05945	COG2770	Histidine kinase
OIM89_RS05975	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OIM89_RS05980	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OIM89_RS05985	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
OIM89_RS06005	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
OIM89_RS06010	COG0612	Peptidase, M16
OIM89_RS06015	COG1185	polyribonucleotide nucleotidyltransferase activity
OIM89_RS06020	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
OIM89_RS06030	COG0455	bacterial-type flagellum organization
OIM89_RS06035	COG0747	negative chemotaxis
OIM89_RS06040	COG0601	transmembrane transport
OIM89_RS06045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OIM89_RS06055	COG4608	Belongs to the ABC transporter superfamily
OIM89_RS06075	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OIM89_RS06080	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OIM89_RS06090	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
OIM89_RS06105	COG0779	Required for maturation of 30S ribosomal subunits
OIM89_RS06125	COG0442	prolyl-tRNA aminoacylation
OIM89_RS06145	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OIM89_RS06150	COG0601	transmembrane transport
OIM89_RS06170	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
OIM89_RS06175	COG0750	zinc metalloprotease
OIM89_RS06180	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
OIM89_RS06185	COG1940	carbohydrate kinase activity
OIM89_RS06190	COG1012	belongs to the aldehyde dehydrogenase family
OIM89_RS06195	COG2508	Transcriptional regulator
OIM89_RS06195	COG2508	Transcriptional regulator
OIM89_RS06225	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OIM89_RS06230	COG1177	transmembrane transport
OIM89_RS06240	COG3842	ATPase activity
OIM89_RS06250	COG1012	belongs to the aldehyde dehydrogenase family
OIM89_RS06265	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
OIM89_RS06285	COG1012	belongs to the aldehyde dehydrogenase family
OIM89_RS06295	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
OIM89_RS06305	COG1136	(ABC) transporter
OIM89_RS06325	COG3842	ATPase activity
OIM89_RS06330	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
OIM89_RS06340	COG0820	rRNA (adenine-C2-)-methyltransferase activity
OIM89_RS06345	COG0575	Belongs to the CDS family
OIM89_RS06350	COG0233	cytoplasmic translational termination
OIM89_RS06355	COG0528	UMP kinase activity
OIM89_RS06360	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
OIM89_RS06365	COG0052	Belongs to the universal ribosomal protein uS2 family
OIM89_RS06380	COG1191	sigma factor activity
OIM89_RS06395	COG0792	nuclease activity
OIM89_RS06410	COG0681	Belongs to the peptidase S26 family
OIM89_RS06415	COG0681	Belongs to the peptidase S26 family
OIM89_RS06420	COG0681	Belongs to the peptidase S26 family
OIM89_RS06430	COG0335	large ribosomal subunit rRNA binding
OIM89_RS06435	COG0336	Belongs to the RNA methyltransferase TrmD family
OIM89_RS06440	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OIM89_RS06445	COG1837	Belongs to the UPF0109 family
OIM89_RS06450	COG0228	four-way junction DNA binding
OIM89_RS06465	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OIM89_RS06475	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
OIM89_RS06505	COG0477	Major facilitator Superfamily
OIM89_RS06510	COG1196	nuclear chromosome segregation
OIM89_RS06520	COG1254	Belongs to the acylphosphatase family
OIM89_RS06525	COG2340	Cysteine-rich secretory protein family
OIM89_RS06530	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
OIM89_RS06535	COG0571	ribonuclease III activity
OIM89_RS06540	COG0333	Belongs to the bacterial ribosomal protein bL32 family
OIM89_RS06555	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
OIM89_RS06560	COG0742	ribosomal rna small subunit methyltransferase
OIM89_RS06570	COG1461	Dihydroxyacetone kinase
OIM89_RS06575	COG0227	Belongs to the bacterial ribosomal protein bL28 family
OIM89_RS06580	COG0351	phosphomethylpyrimidine kinase
OIM89_RS06600	COG1181	Belongs to the D-alanine--D-alanine ligase family
OIM89_RS06605	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
OIM89_RS06615	COG1920	GTP binding
OIM89_RS06625	COG0776	regulation of translation
OIM89_RS06635	COG0066	3-isopropylmalate dehydratase activity
OIM89_RS06640	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OIM89_RS06645	COG1414	Transcriptional regulator
OIM89_RS06690	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OIM89_RS06695	COG0179	Fumarylacetoacetate (FAA) hydrolase
OIM89_RS06710	COG2018	Roadblock/LC7 domain
OIM89_RS06730	COG2018	Roadblock/LC7 domain
OIM89_RS06750	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OIM89_RS06760	COG2353	YceI-like domain
OIM89_RS06805	COG0789	Transcriptional regulator
OIM89_RS06845	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OIM89_RS06855	COG2957	Belongs to the agmatine deiminase family
OIM89_RS06860	COG0804	urea catabolic process
OIM89_RS06865	COG0832	Belongs to the urease beta subunit family
OIM89_RS06865	COG0831	urea catabolic process
OIM89_RS06870	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OIM89_RS06875	COG0473	3-isopropylmalate dehydrogenase activity
OIM89_RS06890	COG0575	Belongs to the CDS family
OIM89_RS06905	COG1012	belongs to the aldehyde dehydrogenase family
OIM89_RS06910	COG0506	proline dehydrogenase activity
OIM89_RS06915	COG3835	regulator
OIM89_RS06935	COG2890	protein-(glutamine-N5) methyltransferase activity
OIM89_RS06945	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
OIM89_RS06950	COG0440	acetolactate synthase activity
OIM89_RS06970	COG0667	Aldo Keto reductase
OIM89_RS06975	COG2133	pyrroloquinoline quinone binding
OIM89_RS06985	COG1672	PFAM Archaeal ATPase
OIM89_RS06985	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
OIM89_RS07005	COG2409	Drug exporters of the RND superfamily
OIM89_RS07010	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OIM89_RS07020	COG0154	amidase activity
OIM89_RS07025	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OIM89_RS07035	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OIM89_RS07045	COG4221	oxidoreductase activity
OIM89_RS07060	COG0596	Alpha beta hydrolase
OIM89_RS07065	COG0482	sulfurtransferase activity
OIM89_RS07090	COG2860	membrane
OIM89_RS07095	COG4608	Belongs to the ABC transporter superfamily
OIM89_RS07100	COG0444	Belongs to the ABC transporter superfamily
OIM89_RS07105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OIM89_RS07110	COG0601	transmembrane transport
OIM89_RS07115	COG4166	transmembrane transport
OIM89_RS07135	COG0404	The glycine cleavage system catalyzes the degradation of glycine
OIM89_RS07140	COG0509	glycine decarboxylation via glycine cleavage system
OIM89_RS07145	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OIM89_RS07150	COG1760	l-serine dehydratase
OIM89_RS07180	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
OIM89_RS07185	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
OIM89_RS07190	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
OIM89_RS07205	COG0477	Major facilitator Superfamily
OIM89_RS07220	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OIM89_RS07245	COG2085	NADP oxidoreductase coenzyme F420-dependent
OIM89_RS07275	COG1376	ErfK ybiS ycfS ynhG family protein
OIM89_RS07295	COG1131	(ABC) transporter
OIM89_RS07300	COG1132	(ABC) transporter
OIM89_RS07305	COG1132	(ABC) transporter
OIM89_RS07325	COG0366	Alpha amylase catalytic
OIM89_RS07330	COG0366	Alpha amylase catalytic
OIM89_RS07335	COG3281	Trehalose synthase
OIM89_RS07340	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
OIM89_RS07360	COG1119	ATPase activity
OIM89_RS07380	COG1301	dicarboxylic acid transport
OIM89_RS07385	COG3290	protein histidine kinase activity
OIM89_RS07390	COG4565	transcriptional regulatory protein
OIM89_RS07395	COG0205	6-phosphofructokinase activity
OIM89_RS07400	COG0280	phosphate acetyltransferase
OIM89_RS07400	COG0857	belongs to the CobB CobQ family
OIM89_RS07405	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OIM89_RS07445	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OIM89_RS07445	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OIM89_RS07510	COG1335	isochorismatase
OIM89_RS07515	COG2205	protein histidine kinase activity
OIM89_RS07545	COG0829	nickel cation binding
OIM89_RS07550	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OIM89_RS07555	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OIM89_RS07570	COG0183	Belongs to the thiolase family
OIM89_RS07590	COG1131	(ABC) transporter
OIM89_RS07625	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
OIM89_RS07640	COG1250	3-hydroxyacyl-CoA dehydrogenase
OIM89_RS07655	COG4585	Histidine kinase
OIM89_RS07660	COG2197	response regulator
OIM89_RS07680	COG0355	proton-transporting ATP synthase activity, rotational mechanism
OIM89_RS07685	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OIM89_RS07690	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
OIM89_RS07695	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OIM89_RS07700	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OIM89_RS07705	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
OIM89_RS07710	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OIM89_RS07725	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OIM89_RS07730	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OIM89_RS07740	COG2890	protein-(glutamine-N5) methyltransferase activity
OIM89_RS07745	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OIM89_RS07750	COG0254	rRNA binding
OIM89_RS07755	COG1316	TRANSCRIPTIONal
OIM89_RS07765	COG0083	homoserine kinase activity
OIM89_RS07770	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OIM89_RS07775	COG0460	homoserine dehydrogenase
OIM89_RS07780	COG0019	diaminopimelate decarboxylase activity
OIM89_RS07785	COG0018	arginyl-trna synthetase
OIM89_RS07850	COG2188	Transcriptional regulator
OIM89_RS07920	COG1012	belongs to the aldehyde dehydrogenase family
OIM89_RS07930	COG1191	sigma factor activity
OIM89_RS07935	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
OIM89_RS07935	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OIM89_RS07945	COG2267	carboxylic ester hydrolase activity
OIM89_RS07950	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
OIM89_RS07955	COG1793	dna ligase
OIM89_RS07955	COG3285	dna ligase
OIM89_RS07965	COG0772	Belongs to the SEDS family
OIM89_RS07970	COG0768	penicillin binding
OIM89_RS08045	COG0726	polysaccharide deacetylase
OIM89_RS08050	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
OIM89_RS08055	COG0477	Major facilitator Superfamily
OIM89_RS08070	COG1595	DNA-templated transcription, initiation
OIM89_RS08080	COG1131	(ABC) transporter
OIM89_RS08100	COG0745	RESPONSE REGULATOR receiver
OIM89_RS08105	COG2205	protein histidine kinase activity
OIM89_RS08110	COG0508	dehydrogenase complex catalyzes the overall conversion of
OIM89_RS08110	COG0567	Dehydrogenase, E1 component
OIM89_RS08140	COG2255	four-way junction helicase activity
OIM89_RS08180	COG0604	alcohol dehydrogenase
OIM89_RS08185	COG0281	malic enzyme
OIM89_RS08190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OIM89_RS08200	COG1126	abc transporter atp-binding protein
OIM89_RS08205	COG4106	trans-aconitate 2-methyltransferase activity
OIM89_RS08230	COG0789	Transcriptional regulator
OIM89_RS08255	COG0142	geranyltranstransferase activity
OIM89_RS08265	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OIM89_RS08270	COG1959	2 iron, 2 sulfur cluster binding
OIM89_RS08290	COG2515	1-aminocyclopropane-1-carboxylate deaminase
OIM89_RS08305	COG2172	sigma factor antagonist activity
OIM89_RS08320	COG1597	lipid kinase activity
OIM89_RS08335	COG0363	glucosamine-6-phosphate deaminase activity
OIM89_RS08340	COG1472	Belongs to the glycosyl hydrolase 3 family
OIM89_RS08345	COG0395	ABC-type sugar transport system, permease component
OIM89_RS08350	COG1175	transmembrane transport
OIM89_RS08355	COG2182	Extracellular solute-binding protein
OIM89_RS08360	COG2188	Transcriptional regulator
OIM89_RS08365	COG1966	Carbon starvation protein
OIM89_RS08385	COG2124	cytochrome p450
OIM89_RS08395	COG0242	peptide deformylase activity
OIM89_RS08405	COG5662	AntiSigma factor
OIM89_RS08410	COG1595	DNA-templated transcription, initiation
OIM89_RS08420	COG2135	peptidase activity
OIM89_RS08430	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
OIM89_RS08440	COG2076	Multidrug Resistance protein
OIM89_RS08450	COG0483	inositol monophosphate 1-phosphatase activity
OIM89_RS08455	COG0753	catalase activity
OIM89_RS08480	COG1615	UPF0182 protein
OIM89_RS08490	COG3480	Lon protease (S16) C-terminal proteolytic domain
OIM89_RS08585	COG0210	DNA helicase
OIM89_RS08675	COG0513	Belongs to the DEAD box helicase family
OIM89_RS08685	COG1432	Conserved Protein
OIM89_RS08695	COG2095	MarC family integral membrane protein
OIM89_RS08700	COG0613	PHP domain protein
OIM89_RS08705	COG2814	Major facilitator Superfamily
OIM89_RS08715	COG0598	Magnesium transport protein CorA
OIM89_RS08755	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OIM89_RS08760	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OIM89_RS08770	COG1595	DNA-templated transcription, initiation
OIM89_RS08785	COG1024	Enoyl-CoA hydratase
OIM89_RS08795	COG0519	Catalyzes the synthesis of GMP from XMP
OIM89_RS08820	COG2207	Transcriptional regulator
OIM89_RS08825	COG1611	Belongs to the LOG family
OIM89_RS08830	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OIM89_RS08865	COG2912	Transglutaminase-like superfamily
OIM89_RS08875	COG1609	Transcriptional regulator
OIM89_RS08880	COG1172	Belongs to the binding-protein-dependent transport system permease family
OIM89_RS08890	COG1129	ABC transporter
OIM89_RS08895	COG1879	ABC-type sugar transport system periplasmic component
OIM89_RS08900	COG3250	beta-galactosidase activity
OIM89_RS08920	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
OIM89_RS08940	COG4608	Belongs to the ABC transporter superfamily
OIM89_RS08950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OIM89_RS08955	COG0601	transmembrane transport
OIM89_RS08965	COG4608	Belongs to the ABC transporter superfamily
OIM89_RS08970	COG0444	Belongs to the ABC transporter superfamily
OIM89_RS08975	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OIM89_RS08980	COG0601	transmembrane transport
OIM89_RS08990	COG1217	gtp-binding protein TYPA
OIM89_RS09045	COG1554	hydrolase, family 65, central catalytic
OIM89_RS09095	COG1028	Short-chain dehydrogenase reductase Sdr
OIM89_RS09100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OIM89_RS09110	COG3473	Maleate cis-trans isomerase
OIM89_RS09115	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OIM89_RS09130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OIM89_RS09135	COG0765	amino acid transport
OIM89_RS09140	COG0765	amino acid transport
OIM89_RS09145	COG1126	abc transporter atp-binding protein
OIM89_RS09175	COG3397	chitin binding
OIM89_RS09230	COG0673	inositol 2-dehydrogenase activity
OIM89_RS09235	COG0179	Fumarylacetoacetate (FAA) hydrolase
OIM89_RS09240	COG0706	membrane insertase activity
OIM89_RS09285	COG2271	Major facilitator Superfamily
OIM89_RS09295	COG2733	membrane
OIM89_RS09325	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OIM89_RS09335	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
OIM89_RS09360	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OIM89_RS09370	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
OIM89_RS09375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OIM89_RS09380	COG1263	PTS System
OIM89_RS09390	COG1234	tRNA 3'-trailer cleavage
OIM89_RS09415	COG1113	amino acid transport
OIM89_RS09430	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
OIM89_RS09440	COG1335	isochorismatase
OIM89_RS09475	COG0277	FAD linked oxidase domain protein
OIM89_RS09485	COG3185	4-Hydroxyphenylpyruvate dioxygenase
OIM89_RS09495	COG1174	glycine betaine transport
OIM89_RS09500	COG1125	glycine betaine transport
OIM89_RS09500	COG0517	IMP dehydrogenase activity
OIM89_RS09505	COG1174	glycine betaine transport
OIM89_RS09555	COG1121	(ABC) transporter
OIM89_RS09570	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
OIM89_RS09575	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OIM89_RS09585	COG2318	DinB family
OIM89_RS09615	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
OIM89_RS09620	COG2318	DinB family
OIM89_RS09635	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OIM89_RS09650	COG3525	Glycosyl hydrolase, family 20, catalytic domain
OIM89_RS09655	COG0395	ABC-type sugar transport system, permease component
OIM89_RS09660	COG1175	transmembrane transport
OIM89_RS09675	COG1678	Uncharacterized ACR, COG1678
OIM89_RS09680	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OIM89_RS09685	COG0776	regulation of translation
OIM89_RS09695	COG3973	AAA domain
OIM89_RS09695	COG3973	AAA domain
OIM89_RS09740	COG0583	DNA-binding transcription factor activity
OIM89_RS09755	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
OIM89_RS09760	COG0793	Belongs to the peptidase S41A family
OIM89_RS09770	COG2884	Cell division ATP-binding protein ftsE
OIM89_RS09785	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
OIM89_RS09790	COG0515	serine threonine protein kinase
OIM89_RS09795	COG0515	serine threonine protein kinase
OIM89_RS09800	COG1716	ATPase activity
OIM89_RS09805	COG1653	transport
OIM89_RS09810	COG1175	transmembrane transport
OIM89_RS09815	COG0395	ABC-type sugar transport system, permease component
OIM89_RS09820	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OIM89_RS09825	COG0438	transferase activity, transferring glycosyl groups
OIM89_RS09830	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OIM89_RS09835	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OIM89_RS09845	COG2226	methyltransferase
OIM89_RS09860	COG2902	Dehydrogenase
OIM89_RS09880	COG0583	DNA-binding transcription factor activity
OIM89_RS09890	COG0653	protein targeting
OIM89_RS09895	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OIM89_RS09900	COG3214	Protein conserved in bacteria
OIM89_RS09905	COG2197	response regulator
OIM89_RS09910	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
OIM89_RS09920	COG0823	Involved in the tonB-independent uptake of proteins
OIM89_RS09925	COG5002	protein histidine kinase activity
OIM89_RS09930	COG0745	RESPONSE REGULATOR receiver
OIM89_RS09935	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
OIM89_RS09955	COG0714	Associated with various cellular activities
OIM89_RS09985	COG3293	Transposase
OIM89_RS10005	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
OIM89_RS10015	COG1482	cell wall glycoprotein biosynthetic process
OIM89_RS10025	COG2835	tetraacyldisaccharide 4'-kinase activity
OIM89_RS10035	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OIM89_RS10045	COG3293	Transposase
OIM89_RS10050	COG1620	l-lactate permease
OIM89_RS10085	COG0391	Required for morphogenesis under gluconeogenic growth conditions
OIM89_RS10090	COG0778	Nitroreductase
OIM89_RS10090	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
OIM89_RS10120	COG1316	TRANSCRIPTIONal
OIM89_RS10140	COG1316	TRANSCRIPTIONal
OIM89_RS10145	COG3046	protein related to deoxyribodipyrimidine photolyase
OIM89_RS10180	COG0753	catalase activity
OIM89_RS10210	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OIM89_RS10215	COG2197	response regulator
OIM89_RS10220	COG4585	Histidine kinase
OIM89_RS10225	COG1136	(ABC) transporter
OIM89_RS10225	COG0577	efflux transmembrane transporter activity
OIM89_RS10240	COG2072	flavoprotein involved in K transport
OIM89_RS10280	COG2205	protein histidine kinase activity
OIM89_RS10285	COG0745	RESPONSE REGULATOR receiver
OIM89_RS10290	COG3104	oligopeptide transport
OIM89_RS10295	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OIM89_RS10305	COG1366	Belongs to the anti-sigma-factor antagonist family
OIM89_RS10310	COG1191	sigma factor activity
OIM89_RS10315	COG1228	amidohydrolase
OIM89_RS10345	COG0395	ABC-type sugar transport system, permease component
OIM89_RS10415	COG2755	lipolytic protein G-D-S-L family
OIM89_RS10420	COG0183	Belongs to the thiolase family
OIM89_RS10445	COG1476	TRANSCRIPTIONal
OIM89_RS10460	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
OIM89_RS10470	COG1136	(ABC) transporter
OIM89_RS10475	COG0577	efflux transmembrane transporter activity
OIM89_RS10475	COG1136	(ABC) transporter
OIM89_RS10480	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
OIM89_RS10485	COG1252	NADH dehydrogenase
OIM89_RS10520	COG0148	phosphopyruvate hydratase activity
OIM89_RS10535	COG2124	cytochrome p450
OIM89_RS10580	COG3547	Transposase (IS116 IS110 IS902 family)
OIM89_RS10605	COG0667	Aldo Keto reductase
OIM89_RS10640	COG0154	amidase activity
OIM89_RS10645	COG3226	Transcriptional regulator
OIM89_RS10655	COG1473	amidohydrolase
OIM89_RS10710	COG3629	intracellular signal transduction
OIM89_RS10710	COG3903	Transcriptional regulator
OIM89_RS10720	COG0477	Major facilitator Superfamily
OIM89_RS10755	COG2267	carboxylic ester hydrolase activity
OIM89_RS10765	COG1316	TRANSCRIPTIONal
OIM89_RS10810	COG4585	Histidine kinase
OIM89_RS10820	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OIM89_RS10825	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OIM89_RS10845	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
OIM89_RS10850	COG0193	aminoacyl-tRNA hydrolase activity
OIM89_RS10865	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
OIM89_RS10880	COG4106	trans-aconitate 2-methyltransferase activity
OIM89_RS10890	COG2197	response regulator
OIM89_RS10895	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
OIM89_RS10940	COG0488	(ABC) transporter
OIM89_RS10945	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
OIM89_RS10950	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
OIM89_RS10955	COG0084	hydrolase, TatD family'
OIM89_RS10980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OIM89_RS11075	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
OIM89_RS11125	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OIM89_RS11135	COG2409	Drug exporters of the RND superfamily
OIM89_RS11145	COG0793	Belongs to the peptidase S41A family
OIM89_RS11145	COG4946	Tricorn protease homolog
OIM89_RS11155	COG4221	oxidoreductase activity
OIM89_RS11165	COG2072	flavoprotein involved in K transport
OIM89_RS11175	COG0708	Exodeoxyribonuclease III
OIM89_RS11185	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OIM89_RS11205	COG2197	response regulator
OIM89_RS11235	COG0315	cyclic pyranopterin monophosphate synthase activity
OIM89_RS11235	COG0521	Mo-molybdopterin cofactor biosynthetic process
OIM89_RS11240	COG0315	cyclic pyranopterin monophosphate synthase activity
OIM89_RS11250	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OIM89_RS11255	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OIM89_RS11265	COG3263	regulation of cellular component size
OIM89_RS11280	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
OIM89_RS11290	COG1970	mechanosensitive ion channel activity
OIM89_RS11305	COG3547	Transposase (IS116 IS110 IS902 family)
OIM89_RS11310	COG3191	aminopeptidase activity
OIM89_RS11330	COG3384	dioxygenase
OIM89_RS11335	COG1846	Transcriptional regulator
OIM89_RS11395	COG2050	protein possibly involved in aromatic compounds catabolism
OIM89_RS11405	COG0183	Belongs to the thiolase family
OIM89_RS11410	COG1024	Enoyl-CoA hydratase
OIM89_RS11415	COG1250	3-hydroxyacyl-CoA dehydrogenase
OIM89_RS11420	COG3396	Phenylacetate-CoA oxygenase
OIM89_RS11425	COG3460	Phenylacetate-CoA oxygenase
OIM89_RS11430	COG3396	Phenylacetate-CoA oxygenase
OIM89_RS11435	COG2151	metal-sulfur cluster biosynthetic enzyme
OIM89_RS11440	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIM89_RS11480	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OIM89_RS11485	COG0191	fructose-bisphosphate aldolase activity
OIM89_RS11490	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OIM89_RS11515	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OIM89_RS11545	COG0515	serine threonine protein kinase
OIM89_RS11545	COG2815	serine threonine protein kinase
OIM89_RS11560	COG1278	Cold shock
OIM89_RS11640	COG5297	Belongs to the glycosyl hydrolase family 6
OIM89_RS11660	COG0148	phosphopyruvate hydratase activity
OIM89_RS11675	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
OIM89_RS11710	COG0815	Transfers the fatty acyl group on membrane lipoproteins
OIM89_RS11715	COG1609	Transcriptional regulator
OIM89_RS11730	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OIM89_RS11735	COG1028	Short-chain dehydrogenase reductase Sdr
OIM89_RS11745	COG0477	Major facilitator Superfamily
OIM89_RS11805	COG1309	transcriptional regulator
OIM89_RS11825	COG2072	flavoprotein involved in K transport
OIM89_RS11830	COG2271	Major facilitator Superfamily
OIM89_RS11850	COG1366	Belongs to the anti-sigma-factor antagonist family
OIM89_RS11935	COG4821	SIS domain
OIM89_RS11945	COG0259	pyridoxamine-phosphate oxidase activity
OIM89_RS11965	COG1024	Enoyl-CoA hydratase
OIM89_RS11980	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OIM89_RS12030	COG0583	DNA-binding transcription factor activity
OIM89_RS12035	COG0247	lactate metabolic process
OIM89_RS12035	COG0277	FAD linked oxidase domain protein
OIM89_RS12040	COG2205	protein histidine kinase activity
OIM89_RS12060	COG2124	cytochrome p450
OIM89_RS12065	COG2124	cytochrome p450
OIM89_RS12070	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
OIM89_RS12165	COG0667	Aldo Keto reductase
OIM89_RS12190	COG2252	PERMEase
OIM89_RS12200	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
OIM89_RS12225	COG2814	Major facilitator Superfamily
OIM89_RS12235	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OIM89_RS12240	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
OIM89_RS12255	COG2197	response regulator
OIM89_RS12260	COG1132	(ABC) transporter
OIM89_RS12265	COG1132	(ABC) transporter
OIM89_RS12275	COG0515	serine threonine protein kinase
OIM89_RS12280	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OIM89_RS12285	COG1120	ATPase activity
OIM89_RS12290	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OIM89_RS12295	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OIM89_RS12310	COG1295	ribonuclease BN
OIM89_RS12320	COG2124	cytochrome p450
OIM89_RS12365	COG1061	Type III restriction enzyme res subunit
OIM89_RS12440	COG3973	AAA domain
OIM89_RS12530	COG0406	alpha-ribazole phosphatase activity
OIM89_RS12540	COG1737	Transcriptional regulator
OIM89_RS12545	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
OIM89_RS12550	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OIM89_RS12550	COG1263	PTS System
OIM89_RS12555	COG0667	Aldo Keto reductase
OIM89_RS12590	COG1278	Cold shock
OIM89_RS12605	COG0463	Glycosyl transferase, family 2
OIM89_RS12685	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OIM89_RS12720	COG1105	Belongs to the carbohydrate kinase PfkB family
OIM89_RS12745	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
OIM89_RS12760	COG1063	alcohol dehydrogenase
OIM89_RS12775	COG1309	transcriptional regulator
OIM89_RS12790	COG1136	(ABC) transporter
OIM89_RS12825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OIM89_RS12950	COG0577	efflux transmembrane transporter activity
OIM89_RS12950	COG1136	(ABC) transporter
OIM89_RS12955	COG0577	efflux transmembrane transporter activity
OIM89_RS13015	COG4585	Histidine kinase
OIM89_RS13020	COG2197	response regulator
OIM89_RS13025	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OIM89_RS13030	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OIM89_RS13050	COG0301	tRNA thio-modification
OIM89_RS13070	COG0513	Belongs to the DEAD box helicase family
OIM89_RS13075	COG1278	Cold shock
OIM89_RS13105	COG2208	phosphoserine phosphatase activity
OIM89_RS13105	COG2770	Histidine kinase
OIM89_RS13150	COG3842	ATPase activity
OIM89_RS13160	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OIM89_RS13170	COG1253	flavin adenine dinucleotide binding
OIM89_RS13185	COG0215	cysteine-tRNA ligase activity
OIM89_RS13200	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OIM89_RS13220	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
OIM89_RS13225	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
OIM89_RS13230	COG1329	Transcriptional regulator
OIM89_RS13240	COG0745	RESPONSE REGULATOR receiver
OIM89_RS13245	COG5002	protein histidine kinase activity
OIM89_RS13250	COG0704	Plays a role in the regulation of phosphate uptake
OIM89_RS13260	COG2076	Multidrug Resistance protein
OIM89_RS13285	COG3311	Transcriptional regulator
OIM89_RS13295	COG0588	phosphoglycerate mutase activity
OIM89_RS13320	COG0438	transferase activity, transferring glycosyl groups
OIM89_RS13355	COG1309	transcriptional regulator
OIM89_RS13375	COG2226	methyltransferase
OIM89_RS13385	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OIM89_RS13460	COG0789	Transcriptional regulator
OIM89_RS13475	COG1490	D-aminoacyl-tRNA deacylase activity
OIM89_RS13480	COG0404	The glycine cleavage system catalyzes the degradation of glycine
OIM89_RS13485	COG0735	belongs to the Fur family
OIM89_RS13490	COG3485	protocatechuate 3,4-dioxygenase
OIM89_RS13525	COG2897	thiosulfate sulfurtransferase activity
OIM89_RS13550	COG0745	RESPONSE REGULATOR receiver
OIM89_RS13555	COG1609	Transcriptional regulator
OIM89_RS13560	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OIM89_RS13565	COG0745	RESPONSE REGULATOR receiver
OIM89_RS13580	COG4214	carbohydrate transport
OIM89_RS13585	COG1129	ABC transporter
OIM89_RS13595	COG1609	Transcriptional regulator
OIM89_RS13600	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OIM89_RS13635	COG2160	L-arabinose isomerase activity
OIM89_RS13640	COG0235	Class ii aldolase
OIM89_RS13645	COG0737	Belongs to the 5'-nucleotidase family
OIM89_RS13650	COG0456	acetyltransferase
OIM89_RS13675	COG4941	Belongs to the sigma-70 factor family
OIM89_RS13680	COG1725	Transcriptional regulator
OIM89_RS13690	COG1131	(ABC) transporter
OIM89_RS13710	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
OIM89_RS13725	COG3547	Transposase (IS116 IS110 IS902 family)
OIM89_RS13740	COG2267	carboxylic ester hydrolase activity
OIM89_RS13760	COG2226	methyltransferase
OIM89_RS13775	COG1595	DNA-templated transcription, initiation
OIM89_RS13820	COG3903	Transcriptional regulator
OIM89_RS13820	COG3629	intracellular signal transduction
OIM89_RS13825	COG0596	Alpha beta hydrolase
OIM89_RS13835	COG2208	phosphoserine phosphatase activity
OIM89_RS13835	COG2770	Histidine kinase
OIM89_RS13890	COG2318	DinB family
OIM89_RS13895	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OIM89_RS13905	COG0406	alpha-ribazole phosphatase activity
OIM89_RS13905	COG0494	nUDIX hydrolase
OIM89_RS13925	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OIM89_RS13930	COG0306	phosphate transporter
OIM89_RS13940	COG1937	Protein conserved in bacteria
OIM89_RS13950	COG1028	Short-chain dehydrogenase reductase Sdr
OIM89_RS13965	COG0671	phosphoesterase, PA-phosphatase related
OIM89_RS13970	COG0739	heme binding
OIM89_RS13970	COG0741	lytic transglycosylase activity
OIM89_RS13970	COG1196	nuclear chromosome segregation
OIM89_RS13985	COG2318	DinB family
OIM89_RS13995	COG0509	glycine decarboxylation via glycine cleavage system
OIM89_RS14045	COG2175	clavaminate synthase activity
OIM89_RS14050	COG3251	PFAM MbtH domain protein
OIM89_RS14055	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OIM89_RS14075	COG1136	(ABC) transporter
OIM89_RS14075	COG0577	efflux transmembrane transporter activity
OIM89_RS14115	COG2124	cytochrome p450
OIM89_RS14120	COG0596	Alpha beta hydrolase
OIM89_RS14135	COG0798	PFAM Bile acid sodium symporter
OIM89_RS14140	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OIM89_RS14155	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OIM89_RS14175	COG2197	response regulator
OIM89_RS14180	COG4585	Histidine kinase
OIM89_RS14185	COG0702	epimerase
OIM89_RS14195	COG3844	kynureninase activity
OIM89_RS14215	COG0477	Major facilitator Superfamily
OIM89_RS14220	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
OIM89_RS14225	COG0191	fructose-bisphosphate aldolase activity
OIM89_RS14230	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OIM89_RS14245	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
OIM89_RS14275	COG2378	regulation of single-species biofilm formation
OIM89_RS14285	COG0542	response to heat
OIM89_RS14290	COG0477	Major facilitator Superfamily
OIM89_RS14315	COG0789	Transcriptional regulator
OIM89_RS14320	COG0484	heat shock protein binding
OIM89_RS14325	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
OIM89_RS14330	COG0443	Heat shock 70 kDa protein
OIM89_RS14365	COG1725	Transcriptional regulator
OIM89_RS14370	COG1131	(ABC) transporter
OIM89_RS14385	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
OIM89_RS14390	COG1120	ATPase activity
OIM89_RS14395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OIM89_RS14400	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OIM89_RS14440	COG1695	Transcriptional regulator
OIM89_RS14450	COG2814	Major facilitator Superfamily
OIM89_RS14465	COG0717	Belongs to the dCTP deaminase family
OIM89_RS14495	COG0247	lactate metabolic process
OIM89_RS14495	COG2181	nitrate reductase activity
OIM89_RS14500	COG0657	acetylesterase activity
OIM89_RS14525	COG0477	Major facilitator Superfamily
OIM89_RS14535	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OIM89_RS14575	COG1937	Protein conserved in bacteria
OIM89_RS14580	COG2268	Band 7 protein
OIM89_RS14595	COG1316	TRANSCRIPTIONal
OIM89_RS14635	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OIM89_RS14645	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
OIM89_RS14660	COG1741	Belongs to the pirin family
OIM89_RS14670	COG1960	acyl-CoA dehydrogenase activity
OIM89_RS14690	COG1362	aminopeptidase activity
OIM89_RS14745	COG0508	dehydrogenase complex catalyzes the overall conversion of
OIM89_RS14750	COG0022	dehydrogenase e1 component
OIM89_RS14765	COG0515	serine threonine protein kinase
OIM89_RS14770	COG0515	serine threonine protein kinase
OIM89_RS14795	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OIM89_RS14800	COG0303	'Molybdopterin
OIM89_RS14825	COG1522	sequence-specific DNA binding
OIM89_RS14865	COG1733	regulation of RNA biosynthetic process
OIM89_RS14870	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OIM89_RS14880	COG1716	ATPase activity
OIM89_RS14885	COG1716	ATPase activity
OIM89_RS14905	COG0515	serine threonine protein kinase
OIM89_RS14910	COG3764	Sortase (surface protein transpeptidase)
OIM89_RS14915	COG3764	Sortase (surface protein transpeptidase)
OIM89_RS14940	COG0705	Rhomboid family
OIM89_RS14960	COG1309	transcriptional regulator
OIM89_RS14965	COG1278	Cold shock
OIM89_RS14990	COG0515	serine threonine protein kinase
OIM89_RS15030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OIM89_RS15035	COG0187	DNA topoisomerase II activity
OIM89_RS15040	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
OIM89_RS15045	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OIM89_RS15050	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
OIM89_RS15055	COG0592	DNA-directed DNA polymerase activity
OIM89_RS15060	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
OIM89_RS15065	COG0230	Belongs to the bacterial ribosomal protein bL34 family
OIM89_RS15070	COG0594	ribonuclease P activity
OIM89_RS15075	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
OIM89_RS15080	COG0706	membrane insertase activity
OIM89_RS15090	COG0357	Ribosomal RNA small subunit methyltransferase G
OIM89_RS15095	COG1192	Involved in chromosome partitioning
OIM89_RS15110	COG3118	belongs to the thioredoxin family
OIM89_RS15115	COG0492	ferredoxin-NADP+ reductase activity
OIM89_RS15125	COG1595	DNA-templated transcription, initiation
OIM89_RS15130	COG2815	serine threonine protein kinase
OIM89_RS15130	COG0515	serine threonine protein kinase
OIM89_RS15145	COG0617	tRNA 3'-terminal CCA addition
OIM89_RS15170	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OIM89_RS15195	COG0360	Binds together with S18 to 16S ribosomal RNA
OIM89_RS15200	COG0629	single-stranded DNA binding
OIM89_RS15205	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OIM89_RS15210	COG0359	binds to the 23S rRNA
OIM89_RS15220	COG0305	Participates in initiation and elongation during chromosome replication
OIM89_RS15225	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OIM89_RS15230	COG0110	maltose O-acetyltransferase activity
OIM89_RS15270	COG0626	cystathionine gamma-synthase activity
OIM89_RS15275	COG1950	PFAM Membrane protein of
OIM89_RS15280	COG0662	Cupin 2, conserved barrel domain protein
OIM89_RS15305	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
OIM89_RS15320	COG1609	Transcriptional regulator
OIM89_RS15325	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OIM89_RS15330	COG1271	oxidase subunit
OIM89_RS15335	COG1294	oxidase, subunit
OIM89_RS15340	COG4988	ABC transporter
OIM89_RS15350	COG0739	heme binding
OIM89_RS15350	COG0741	lytic transglycosylase activity
OIM89_RS15350	COG1196	nuclear chromosome segregation
OIM89_RS15355	COG0561	phosphatase activity
OIM89_RS15375	COG1131	(ABC) transporter
OIM89_RS15395	COG0561	phosphatase activity
OIM89_RS15400	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OIM89_RS15405	COG0077	Prephenate dehydratase
OIM89_RS15410	COG2837	iron assimilation
OIM89_RS15425	COG1999	signal sequence binding
OIM89_RS15445	COG0006	proline dipeptidase activity
OIM89_RS15460	COG0653	protein targeting
OIM89_RS15475	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OIM89_RS15495	COG1595	DNA-templated transcription, initiation
OIM89_RS15500	COG0318	PFAM AMP-dependent synthetase and ligase
OIM89_RS15535	COG0745	RESPONSE REGULATOR receiver
OIM89_RS15545	COG0477	Major facilitator Superfamily
OIM89_RS15565	COG0477	Major facilitator Superfamily
OIM89_RS15580	COG1191	sigma factor activity
OIM89_RS15585	COG1191	sigma factor activity
OIM89_RS15620	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
OIM89_RS15685	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OIM89_RS15690	COG2837	iron assimilation
OIM89_RS15700	COG0659	secondary active sulfate transmembrane transporter activity
OIM89_RS15730	COG0151	Belongs to the GarS family
OIM89_RS15745	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
OIM89_RS15755	COG2197	response regulator
OIM89_RS15790	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OIM89_RS15795	COG0047	phosphoribosylformylglycinamidine synthase activity
OIM89_RS15800	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OIM89_RS15815	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
OIM89_RS15850	COG1643	Atp-dependent helicase
OIM89_RS15890	COG0513	Belongs to the DEAD box helicase family
OIM89_RS15920	COG0542	response to heat
OIM89_RS15930	COG2261	transglycosylase associated protein
OIM89_RS15950	COG0667	Aldo Keto reductase
OIM89_RS15960	COG0220	tRNA (guanine-N7-)-methyltransferase activity
OIM89_RS15965	COG0579	oxidoreductase
OIM89_RS15980	COG1470	cell adhesion involved in biofilm formation
OIM89_RS15980	COG0366	Alpha amylase catalytic
OIM89_RS16055	COG0596	Alpha beta hydrolase
OIM89_RS16070	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
OIM89_RS16120	COG2197	response regulator
OIM89_RS16135	COG0666	response to abiotic stimulus
OIM89_RS16210	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
OIM89_RS16215	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OIM89_RS16225	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OIM89_RS16270	COG0596	Alpha beta hydrolase
OIM89_RS16295	COG2318	DinB family
OIM89_RS16310	COG0577	efflux transmembrane transporter activity
OIM89_RS16310	COG1136	(ABC) transporter
OIM89_RS16325	COG1408	metallophosphoesterase
OIM89_RS16345	COG0003	Pfam Anion-transporting ATPase
OIM89_RS16360	COG0251	oxidation-reduction process
OIM89_RS16370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OIM89_RS16400	COG2267	carboxylic ester hydrolase activity
OIM89_RS16410	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
OIM89_RS16415	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OIM89_RS16420	COG0659	secondary active sulfate transmembrane transporter activity
OIM89_RS16480	COG1205	dead DEAH box helicase
OIM89_RS16480	COG1111	helicase
OIM89_RS16485	COG1366	Belongs to the anti-sigma-factor antagonist family
OIM89_RS16500	COG2890	protein-(glutamine-N5) methyltransferase activity
OIM89_RS16510	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OIM89_RS16510	COG1754	DNA topoisomerase type I activity
OIM89_RS16515	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OIM89_RS16555	COG0789	Transcriptional regulator
OIM89_RS16570	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OIM89_RS16575	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OIM89_RS16600	COG0825	malonyl-CoA metabolic process
OIM89_RS16600	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
OIM89_RS16605	COG0318	PFAM AMP-dependent synthetase and ligase
OIM89_RS16615	COG2186	Transcriptional regulator
OIM89_RS16635	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OIM89_RS16645	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
OIM89_RS16695	COG0494	nUDIX hydrolase
OIM89_RS16700	COG1252	NADH dehydrogenase
OIM89_RS16705	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OIM89_RS16715	COG1028	Short-chain dehydrogenase reductase Sdr
OIM89_RS16720	COG0640	Transcriptional regulator
OIM89_RS16730	COG1316	TRANSCRIPTIONal
OIM89_RS16750	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
OIM89_RS16755	COG1309	transcriptional regulator
OIM89_RS16765	COG5001	Diguanylate cyclase
OIM89_RS16795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OIM89_RS16800	COG1120	ATPase activity
OIM89_RS16805	COG0783	Belongs to the Dps family
OIM89_RS16835	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
OIM89_RS16840	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
OIM89_RS16860	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
OIM89_RS16890	COG0456	acetyltransferase
OIM89_RS16890	COG1214	PFAM Peptidase M22, glycoprotease
OIM89_RS16930	COG0739	heme binding
OIM89_RS16940	COG0477	Major facilitator Superfamily
OIM89_RS16940	COG2814	Major facilitator Superfamily
OIM89_RS16955	COG2159	amidohydrolase
OIM89_RS16965	COG2186	Transcriptional regulator
OIM89_RS16995	COG0501	Belongs to the peptidase M48B family
OIM89_RS17000	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OIM89_RS17000	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OIM89_RS17030	COG1289	transmembrane transporter activity
OIM89_RS17055	COG1012	belongs to the aldehyde dehydrogenase family
OIM89_RS17060	COG2318	DinB family
OIM89_RS17070	COG0655	NAD(P)H dehydrogenase (quinone) activity
OIM89_RS17075	COG0789	Transcriptional regulator
OIM89_RS17080	COG0586	Pfam SNARE associated Golgi protein
OIM89_RS17090	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
OIM89_RS17095	COG2027	D-alanyl-D-alanine carboxypeptidase
OIM89_RS17105	COG0037	tRNA processing
OIM89_RS17120	COG0302	gtp cyclohydrolase
OIM89_RS17135	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OIM89_RS17150	COG0517	IMP dehydrogenase activity
OIM89_RS17150	COG1125	glycine betaine transport
OIM89_RS17155	COG1174	glycine betaine transport
OIM89_RS17160	COG1174	glycine betaine transport
OIM89_RS17165	COG1732	Glycine betaine
OIM89_RS17175	COG0477	Major facilitator Superfamily
OIM89_RS17240	COG1012	belongs to the aldehyde dehydrogenase family
OIM89_RS17260	COG4585	Histidine kinase
OIM89_RS17265	COG2197	response regulator
OIM89_RS17285	COG0649	NAD binding
OIM89_RS17300	COG2197	response regulator
OIM89_RS17315	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
OIM89_RS17320	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
OIM89_RS17330	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
OIM89_RS17350	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
OIM89_RS17375	COG0739	heme binding
OIM89_RS17380	COG2205	protein histidine kinase activity
OIM89_RS17385	COG0745	RESPONSE REGULATOR receiver
OIM89_RS17395	COG1595	DNA-templated transcription, initiation
OIM89_RS17405	COG0671	phosphoesterase, PA-phosphatase related
OIM89_RS17415	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
OIM89_RS17445	COG0248	Ppx GppA phosphatase
OIM89_RS17455	COG1082	Xylose isomerase domain protein TIM barrel
OIM89_RS17460	COG1309	transcriptional regulator
OIM89_RS17465	COG0129	dihydroxy-acid dehydratase activity
OIM89_RS17475	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OIM89_RS17495	COG1129	ABC transporter
OIM89_RS17495	COG0842	Transport permease protein
OIM89_RS17505	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OIM89_RS17510	COG0180	Tryptophanyl-tRNA synthetase
OIM89_RS17530	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OIM89_RS17535	COG2223	nitrite transmembrane transporter activity
OIM89_RS17540	COG0123	including yeast histone deacetylase and acetoin utilization protein
OIM89_RS17570	COG4552	Acetyltransferase involved in intracellular survival and related
OIM89_RS17595	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
OIM89_RS17600	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
OIM89_RS17605	COG0181	hydroxymethylbilane synthase activity
OIM89_RS17610	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OIM89_RS17610	COG1648	precorrin-2 dehydrogenase activity
OIM89_RS17615	COG0113	porphobilinogen synthase activity
OIM89_RS17645	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OIM89_RS17650	COG0018	arginyl-trna synthetase
OIM89_RS17655	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
OIM89_RS17680	COG1690	Belongs to the RtcB family
OIM89_RS17685	COG0659	secondary active sulfate transmembrane transporter activity
OIM89_RS17730	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
OIM89_RS17735	COG0406	alpha-ribazole phosphatase activity
OIM89_RS17760	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OIM89_RS17765	COG0785	Cytochrome C biogenesis protein
OIM89_RS17775	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OIM89_RS17790	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
OIM89_RS17795	COG0109	protoheme IX farnesyltransferase activity
OIM89_RS17800	COG0163	prenyltransferase activity
OIM89_RS17815	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
OIM89_RS17830	COG1301	dicarboxylic acid transport
OIM89_RS17905	COG0183	Belongs to the thiolase family
OIM89_RS17915	COG1278	Cold shock
OIM89_RS17920	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
OIM89_RS17925	COG1674	ftsk spoiiie
OIM89_RS18070	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
OIM89_RS18080	COG2226	methyltransferase
OIM89_RS18105	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OIM89_RS18110	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OIM89_RS18115	COG0649	NAD binding
OIM89_RS18125	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
OIM89_RS18130	COG1034	ATP synthesis coupled electron transport
OIM89_RS18135	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
OIM89_RS18140	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OIM89_RS18145	COG0839	Belongs to the complex I subunit 6 family
OIM89_RS18150	COG0713	ATP synthesis coupled electron transport
OIM89_RS18155	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OIM89_RS18165	COG1007	ATP synthesis coupled electron transport
OIM89_RS18190	COG0561	phosphatase activity
OIM89_RS18200	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OIM89_RS18210	COG3104	oligopeptide transport
OIM89_RS18215	COG0142	geranyltranstransferase activity
OIM89_RS18235	COG0488	(ABC) transporter
OIM89_RS18245	COG0702	epimerase
OIM89_RS18250	COG1733	regulation of RNA biosynthetic process
OIM89_RS18255	COG1013	pyruvate-flavodoxin oxidoreductase activity
OIM89_RS18260	COG0674	pyruvate-flavodoxin oxidoreductase activity
OIM89_RS18260	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
OIM89_RS18265	COG2197	response regulator
OIM89_RS18270	COG4585	Histidine kinase
OIM89_RS18275	COG4585	Histidine kinase
OIM89_RS18280	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OIM89_RS18285	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OIM89_RS18290	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OIM89_RS18295	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
OIM89_RS18300	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OIM89_RS18305	COG0839	Belongs to the complex I subunit 6 family
OIM89_RS18310	COG0713	ATP synthesis coupled electron transport
OIM89_RS18315	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OIM89_RS18325	COG1007	ATP synthesis coupled electron transport
OIM89_RS18330	COG0501	Belongs to the peptidase M48B family
OIM89_RS18335	COG3304	Inner membrane component domain
OIM89_RS18340	COG2261	transglycosylase associated protein
OIM89_RS18345	COG1666	GTP binding
OIM89_RS18355	COG0702	epimerase
OIM89_RS18360	COG0402	S-adenosylhomocysteine deaminase activity
OIM89_RS18375	COG0267	Belongs to the bacterial ribosomal protein bL33 family
OIM89_RS18380	COG2030	dehydratase
OIM89_RS18390	COG0812	UDP-N-acetylmuramate dehydrogenase activity
OIM89_RS18400	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
OIM89_RS18405	COG0436	Aminotransferase
OIM89_RS18430	COG0081	regulation of translation
OIM89_RS18440	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
OIM89_RS18445	COG0222	ribosome binding
OIM89_RS18450	COG0085	RNA polymerase activity
OIM89_RS18455	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OIM89_RS18490	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
OIM89_RS18495	COG0049	tRNA binding
OIM89_RS18500	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OIM89_RS18550	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
OIM89_RS18560	COG0051	transcription antitermination factor activity, RNA binding
OIM89_RS18565	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OIM89_RS18570	COG0088	Forms part of the polypeptide exit tunnel
OIM89_RS18575	COG0089	rRNA binding
OIM89_RS18580	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
OIM89_RS18585	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
OIM89_RS18590	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
OIM89_RS18595	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
OIM89_RS18600	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
OIM89_RS18605	COG0255	Belongs to the universal ribosomal protein uL29 family
OIM89_RS18610	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
OIM89_RS18615	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
OIM89_RS18620	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
OIM89_RS18625	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
OIM89_RS18630	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OIM89_RS18635	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
OIM89_RS18640	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OIM89_RS18645	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
OIM89_RS18650	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
OIM89_RS18655	COG1841	ribosomal large subunit assembly
OIM89_RS18660	COG0200	Binds to the 23S rRNA
OIM89_RS18665	COG0201	protein transport
OIM89_RS18670	COG0563	adenylate kinase activity
OIM89_RS18680	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
OIM89_RS18685	COG0257	Belongs to the bacterial ribosomal protein bL36 family
OIM89_RS18690	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
OIM89_RS18695	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
OIM89_RS18705	COG0203	ribosomal protein L17
OIM89_RS18710	COG0101	tRNA pseudouridine synthase activity
OIM89_RS18720	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
OIM89_RS18725	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
OIM89_RS18730	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OIM89_RS18735	COG1072	(Pantothenic acid kinase))
OIM89_RS18750	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OIM89_RS18760	COG4977	sequence-specific DNA binding
OIM89_RS18770	COG0736	holo-[acyl-carrier-protein] synthase activity
OIM89_RS18835	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OIM89_RS18845	COG0802	atpase or kinase
OIM89_RS18870	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OIM89_RS18905	COG0726	polysaccharide deacetylase
OIM89_RS18920	COG4221	oxidoreductase activity
OIM89_RS18925	COG0583	DNA-binding transcription factor activity
OIM89_RS18935	COG2197	response regulator
OIM89_RS18940	COG1595	DNA-templated transcription, initiation
OIM89_RS18950	COG0516	GMP reductase activity
OIM89_RS18960	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
OIM89_RS18995	COG1012	belongs to the aldehyde dehydrogenase family
OIM89_RS19015	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OIM89_RS19015	COG0519	Catalyzes the synthesis of GMP from XMP
OIM89_RS19025	COG1028	Short-chain dehydrogenase reductase Sdr
OIM89_RS19060	COG2197	response regulator
OIM89_RS19065	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OIM89_RS19115	COG0456	acetyltransferase
OIM89_RS19115	COG1846	Transcriptional regulator
OIM89_RS19125	COG1228	amidohydrolase
OIM89_RS19175	COG2066	Belongs to the glutaminase family
OIM89_RS19180	COG0739	heme binding
OIM89_RS19180	COG0741	lytic transglycosylase activity
OIM89_RS19180	COG1196	nuclear chromosome segregation
OIM89_RS19185	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
OIM89_RS19190	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OIM89_RS19190	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OIM89_RS19205	COG0714	Associated with various cellular activities
OIM89_RS19210	COG2425	protein containing a von Willebrand factor type A (vWA) domain
OIM89_RS19215	COG3552	Protein containing von Willebrand factor type A (VWA) domain
OIM89_RS19220	COG0045	succinate-CoA ligase (ADP-forming) activity
OIM89_RS19250	COG0138	bifunctional purine biosynthesis protein purh
OIM89_RS19260	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OIM89_RS19295	COG0039	L-malate dehydrogenase activity
OIM89_RS19315	COG1012	belongs to the aldehyde dehydrogenase family
OIM89_RS19325	COG0517	IMP dehydrogenase activity
OIM89_RS19325	COG4175	Glycine betaine
OIM89_RS19355	COG0395	ABC-type sugar transport system, permease component
OIM89_RS19360	COG1175	transmembrane transport
OIM89_RS19380	COG2362	D-Aminopeptidase
OIM89_RS19385	COG1609	Transcriptional regulator
OIM89_RS19390	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OIM89_RS19395	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OIM89_RS19405	COG0754	glutathionylspermidine amidase activity
OIM89_RS19415	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OIM89_RS19455	COG0180	Tryptophanyl-tRNA synthetase
OIM89_RS19495	COG1295	ribonuclease BN
OIM89_RS19500	COG1686	Belongs to the peptidase S11 family
OIM89_RS19510	COG1408	metallophosphoesterase
OIM89_RS19525	COG1309	transcriptional regulator
OIM89_RS19540	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OIM89_RS19545	COG1053	succinate dehydrogenase
OIM89_RS19555	COG2009	succinate dehydrogenase
OIM89_RS19595	COG1215	transferase activity, transferring glycosyl groups
OIM89_RS19600	COG1595	DNA-templated transcription, initiation
OIM89_RS19630	COG1216	Glycosyl transferase, family 2
OIM89_RS19640	COG1083	cytidylyl-transferase
OIM89_RS19645	COG2089	acid synthase
OIM89_RS19655	COG1473	amidohydrolase
OIM89_RS19655	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
OIM89_RS19680	COG2197	response regulator
OIM89_RS19695	COG1744	ABC transporter substrate-binding protein PnrA-like
OIM89_RS19700	COG3845	ABC transporter
OIM89_RS19705	COG4603	Belongs to the binding-protein-dependent transport system permease family
OIM89_RS19710	COG1079	Belongs to the binding-protein-dependent transport system permease family
OIM89_RS19740	COG2814	Major facilitator Superfamily
OIM89_RS19745	COG0583	DNA-binding transcription factor activity
OIM89_RS19755	COG1136	(ABC) transporter
OIM89_RS19775	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
OIM89_RS19800	COG2205	protein histidine kinase activity
OIM89_RS19805	COG0745	RESPONSE REGULATOR receiver
OIM89_RS19810	COG1595	DNA-templated transcription, initiation
OIM89_RS19855	COG1012	belongs to the aldehyde dehydrogenase family
OIM89_RS19870	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OIM89_RS19905	COG4770	biotin carboxylase activity
OIM89_RS19915	COG0424	maF-like protein
OIM89_RS19930	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OIM89_RS19940	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
OIM89_RS19945	COG1024	Enoyl-CoA hydratase
OIM89_RS19955	COG2986	histidine ammonia-lyase
OIM89_RS19975	COG1136	(ABC) transporter
OIM89_RS19980	COG1064	alcohol dehydrogenase
OIM89_RS19985	COG2318	DinB family
OIM89_RS20010	COG2255	four-way junction helicase activity
OIM89_RS20015	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OIM89_RS20030	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OIM89_RS20040	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
OIM89_RS20075	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
OIM89_RS20100	COG1331	Highly conserved protein containing a thioredoxin domain
OIM89_RS20120	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
OIM89_RS20150	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
OIM89_RS20165	COG1414	Transcriptional regulator
OIM89_RS20170	COG0251	oxidation-reduction process
OIM89_RS20210	COG2894	cell division
OIM89_RS20270	COG2814	Major facilitator Superfamily
OIM89_RS20275	COG0656	L-ascorbic acid biosynthetic process
OIM89_RS20280	COG2304	oxidoreductase activity
OIM89_RS20290	COG3548	integral membrane protein
OIM89_RS20300	COG0667	Aldo Keto reductase
OIM89_RS20305	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OIM89_RS20310	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
OIM89_RS20330	COG0450	alkyl hydroperoxide reductase
OIM89_RS20335	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OIM89_RS20345	COG1136	(ABC) transporter
OIM89_RS20365	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OIM89_RS20380	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OIM89_RS20390	COG0114	fumarate hydratase activity
OIM89_RS20400	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
OIM89_RS20400	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
OIM89_RS20410	COG0515	serine threonine protein kinase
OIM89_RS20435	COG0778	Nitroreductase
OIM89_RS20440	COG1722	exodeoxyribonuclease VII activity
OIM89_RS20445	COG1570	exodeoxyribonuclease VII activity
OIM89_RS20455	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
OIM89_RS20470	COG0012	GTP binding
OIM89_RS20515	COG0406	alpha-ribazole phosphatase activity
OIM89_RS20540	COG0745	RESPONSE REGULATOR receiver
OIM89_RS20605	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
OIM89_RS20610	COG4977	sequence-specific DNA binding
OIM89_RS20625	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OIM89_RS20650	COG3486	L-lysine 6-monooxygenase (NADPH) activity
OIM89_RS20670	COG1028	Short-chain dehydrogenase reductase Sdr
OIM89_RS20720	COG1960	acyl-CoA dehydrogenase activity
OIM89_RS20735	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OIM89_RS20740	COG1309	transcriptional regulator
OIM89_RS20750	COG1946	Acyl-CoA thioesterase
OIM89_RS20785	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OIM89_RS20795	COG3960	tartronate-semialdehyde synthase activity
OIM89_RS20815	COG1472	Belongs to the glycosyl hydrolase 3 family
OIM89_RS20820	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OIM89_RS20860	COG3718	enzyme involved in inositol metabolism
OIM89_RS20865	COG3962	Belongs to the TPP enzyme family
OIM89_RS20880	COG0454	-acetyltransferase
OIM89_RS20880	COG0456	acetyltransferase
OIM89_RS20885	COG1131	(ABC) transporter
OIM89_RS20915	COG3629	intracellular signal transduction
OIM89_RS20915	COG3903	Transcriptional regulator
OIM89_RS20955	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OIM89_RS20995	COG0629	single-stranded DNA binding
OIM89_RS21030	COG1136	(ABC) transporter
OIM89_RS21050	COG0667	Aldo Keto reductase
OIM89_RS21055	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
OIM89_RS21085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OIM89_RS21100	COG1486	melibiose metabolic process
OIM89_RS21110	COG0668	transmembrane transport
OIM89_RS21130	COG3525	Glycosyl hydrolase, family 20, catalytic domain
OIM89_RS21150	COG0583	DNA-binding transcription factor activity
OIM89_RS21205	COG4266	Belongs to the allantoicase family
OIM89_RS21235	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
OIM89_RS21240	COG0076	glutamate decarboxylase activity
OIM89_RS21245	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OIM89_RS21250	COG1113	amino acid transport
OIM89_RS21255	COG1113	amino acid transport
OIM89_RS21260	COG1268	BioY protein
OIM89_RS21265	COG1113	amino acid transport
OIM89_RS21280	COG4552	Acetyltransferase involved in intracellular survival and related
OIM89_RS21290	COG0475	glutathione-regulated potassium exporter activity
OIM89_RS21295	COG3594	Acyltransferase
OIM89_RS21315	COG0544	peptidyl-prolyl cis-trans isomerase activity
OIM89_RS21320	COG0740	serine-type endopeptidase activity
OIM89_RS21325	COG0740	serine-type endopeptidase activity
OIM89_RS21330	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
OIM89_RS21340	COG0525	valine-tRNA ligase activity
OIM89_RS21345	COG0285	dihydrofolate synthase activity
OIM89_RS21355	COG0105	UTP biosynthetic process
OIM89_RS21360	COG1077	Cell shape determining protein MreB Mrl
OIM89_RS21380	COG0772	Belongs to the SEDS family
OIM89_RS21410	COG1530	ribonuclease E activity
OIM89_RS21415	COG0261	This protein binds to 23S rRNA in the presence of protein L20
OIM89_RS21420	COG0211	Belongs to the bacterial ribosomal protein bL27 family
OIM89_RS21425	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OIM89_RS21445	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OIM89_RS21455	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
OIM89_RS21475	COG0501	Belongs to the peptidase M48B family
OIM89_RS21490	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
OIM89_RS21500	COG0799	negative regulation of ribosome biogenesis
OIM89_RS21505	COG0588	phosphoglycerate mutase activity
OIM89_RS21530	COG0495	leucyl-tRNA aminoacylation
OIM89_RS21540	COG1307	EDD domain protein, DegV family
OIM89_RS21545	COG1555	photosystem II stabilization
OIM89_RS21645	COG0268	Binds directly to 16S ribosomal RNA
OIM89_RS21650	COG0481	GTPase activity
OIM89_RS21680	COG0484	heat shock protein binding
OIM89_RS21695	COG4946	Tricorn protease homolog
OIM89_RS21695	COG0793	Belongs to the peptidase S41A family
OIM89_RS21705	COG0537	adenosine 5'-monophosphoramidase activity
OIM89_RS21710	COG1234	tRNA 3'-trailer cleavage
OIM89_RS21730	COG2515	1-aminocyclopropane-1-carboxylate deaminase
OIM89_RS21735	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
OIM89_RS21760	COG1486	melibiose metabolic process
OIM89_RS21765	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OIM89_RS21785	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
OIM89_RS21795	COG2315	Protein conserved in bacteria
OIM89_RS21805	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OIM89_RS21820	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OIM89_RS21830	COG1381	Involved in DNA repair and RecF pathway recombination
OIM89_RS21835	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OIM89_RS21845	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OIM89_RS21850	COG1121	(ABC) transporter
OIM89_RS21860	COG0423	glycine-tRNA ligase activity
OIM89_RS21925	COG3467	pyridoxamine 5'-phosphate
OIM89_RS21935	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
OIM89_RS21940	COG1940	carbohydrate kinase activity
OIM89_RS21940	COG1846	Transcriptional regulator
OIM89_RS21950	COG0574	Belongs to the PEP-utilizing enzyme family
OIM89_RS21950	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OIM89_RS21965	COG1324	tolerance protein
OIM89_RS21975	COG0829	nickel cation binding
OIM89_RS21980	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
OIM89_RS21985	COG0830	nickel cation binding
OIM89_RS21990	COG0804	urea catabolic process
OIM89_RS21995	COG0832	Belongs to the urease beta subunit family
OIM89_RS22020	COG2226	methyltransferase
OIM89_RS22025	COG0736	holo-[acyl-carrier-protein] synthase activity
OIM89_RS22030	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OIM89_RS22040	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OIM89_RS22050	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OIM89_RS22055	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OIM89_RS22065	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OIM89_RS22115	COG1070	Carbohydrate kinase
OIM89_RS22135	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OIM89_RS22140	COG0358	DNA primase activity
OIM89_RS22150	COG3290	protein histidine kinase activity
OIM89_RS22155	COG4565	transcriptional regulatory protein
OIM89_RS22160	COG2851	Citrate transporter
OIM89_RS22180	COG0232	Belongs to the dGTPase family. Type 2 subfamily
OIM89_RS22200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OIM89_RS22230	COG1028	Short-chain dehydrogenase reductase Sdr
OIM89_RS22245	COG2890	protein-(glutamine-N5) methyltransferase activity
OIM89_RS22260	COG1077	Cell shape determining protein MreB Mrl
OIM89_RS22280	COG2130	NADP-dependent
OIM89_RS22285	COG1764	response to oxidative stress
OIM89_RS22320	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OIM89_RS22325	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OIM89_RS22330	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OIM89_RS22345	COG1741	Belongs to the pirin family
OIM89_RS22360	COG0789	Transcriptional regulator
OIM89_RS22365	COG0667	Aldo Keto reductase
OIM89_RS22380	COG2197	response regulator
OIM89_RS22385	COG4585	Histidine kinase
OIM89_RS22405	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
OIM89_RS22450	COG1358	cellular component organization or biogenesis
OIM89_RS22465	COG0586	Pfam SNARE associated Golgi protein
OIM89_RS22590	COG0438	transferase activity, transferring glycosyl groups
OIM89_RS22620	COG0477	Major facilitator Superfamily
OIM89_RS22625	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OIM89_RS22630	COG1960	acyl-CoA dehydrogenase activity
OIM89_RS22655	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OIM89_RS22675	COG0800	Aldolase
OIM89_RS22680	COG3022	response to hydroperoxide
OIM89_RS22710	COG1733	regulation of RNA biosynthetic process
OIM89_RS22730	COG2226	methyltransferase
OIM89_RS22735	COG0384	phenazine biosynthesis protein PhzF
OIM89_RS22755	COG0076	glutamate decarboxylase activity
OIM89_RS22765	COG2814	Major facilitator Superfamily
OIM89_RS22770	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OIM89_RS22780	COG1834	amidinotransferase
OIM89_RS22800	COG1120	ATPase activity
OIM89_RS22805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OIM89_RS22810	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OIM89_RS22825	COG0384	phenazine biosynthesis protein PhzF
OIM89_RS22855	COG1994	Peptidase M50
OIM89_RS22860	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
OIM89_RS22875	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
OIM89_RS22875	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OIM89_RS22880	COG2132	Multicopper oxidase
OIM89_RS22900	COG0174	glutamine synthetase
OIM89_RS22930	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
OIM89_RS22950	COG1228	amidohydrolase
OIM89_RS22965	COG1609	Transcriptional regulator
OIM89_RS22970	COG2182	Extracellular solute-binding protein
OIM89_RS22975	COG1175	transmembrane transport
OIM89_RS22980	COG0395	ABC-type sugar transport system, permease component
OIM89_RS22985	COG0366	Alpha amylase catalytic
OIM89_RS23005	COG0454	-acetyltransferase
OIM89_RS23005	COG0456	acetyltransferase
OIM89_RS23010	COG1309	transcriptional regulator
OIM89_RS23045	COG0745	RESPONSE REGULATOR receiver
OIM89_RS23085	COG1012	belongs to the aldehyde dehydrogenase family
OIM89_RS23150	COG2326	polyphosphate kinase activity
OIM89_RS23165	COG2376	Dihydroxyacetone kinase
OIM89_RS23170	COG2376	Dihydroxyacetone kinase
OIM89_RS23175	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OIM89_RS23210	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OIM89_RS23215	COG0321	lipoyl(octanoyl) transferase activity
OIM89_RS23265	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
OIM89_RS23275	COG0508	dehydrogenase complex catalyzes the overall conversion of
OIM89_RS23280	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OIM89_RS23285	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OIM89_RS23290	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
OIM89_RS23300	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
OIM89_RS23345	COG2197	response regulator
OIM89_RS23350	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OIM89_RS23355	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
OIM89_RS23380	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OIM89_RS23385	COG1104	cysteine desulfurase activity
OIM89_RS23390	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OIM89_RS23395	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OIM89_RS23405	COG1376	ErfK ybiS ycfS ynhG family protein
OIM89_RS23415	COG1845	cytochrome c oxidase, subunit III
OIM89_RS23420	COG2010	Cytochrome c
OIM89_RS23425	COG0723	plastoquinol--plastocyanin reductase activity
OIM89_RS23430	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
OIM89_RS23435	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OIM89_RS23440	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OIM89_RS23445	COG1929	Belongs to the glycerate kinase type-1 family
OIM89_RS23455	COG0745	RESPONSE REGULATOR receiver
OIM89_RS23460	COG5002	protein histidine kinase activity
OIM89_RS23510	COG0438	transferase activity, transferring glycosyl groups
OIM89_RS23530	COG0003	Pfam Anion-transporting ATPase
OIM89_RS23540	COG1940	carbohydrate kinase activity
OIM89_RS23565	COG4585	Histidine kinase
OIM89_RS23570	COG2197	response regulator
OIM89_RS23575	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OIM89_RS23585	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
OIM89_RS23590	COG0243	molybdopterin cofactor binding
OIM89_RS23595	COG2193	ferroxidase activity
OIM89_RS23600	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
OIM89_RS23605	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
OIM89_RS23610	COG2815	serine threonine protein kinase
OIM89_RS23610	COG0515	serine threonine protein kinase
OIM89_RS23615	COG2022	thiamine diphosphate biosynthetic process
OIM89_RS23625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OIM89_RS23625	COG2022	thiamine diphosphate biosynthetic process
OIM89_RS23630	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OIM89_RS23640	COG0352	thiamine-phosphate diphosphorylase activity
OIM89_RS23660	COG1309	transcriptional regulator
OIM89_RS23670	COG1121	(ABC) transporter
OIM89_RS23675	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OIM89_RS23695	COG0714	Associated with various cellular activities
OIM89_RS23705	COG0275	rRNA processing
OIM89_RS23720	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OIM89_RS23730	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OIM89_RS23735	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OIM89_RS23745	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OIM89_RS23750	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
OIM89_RS23755	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OIM89_RS23760	COG1496	oxidoreductase activity
OIM89_RS23770	COG1799	cell septum assembly
OIM89_RS23780	COG3599	regulation of cell shape
OIM89_RS23785	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OIM89_RS23795	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
OIM89_RS23805	COG2153	protein acetylation
OIM89_RS23820	COG0515	serine threonine protein kinase
OIM89_RS23840	COG0587	DNA-directed DNA polymerase activity
OIM89_RS23850	COG1432	Conserved Protein
OIM89_RS23870	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OIM89_RS23890	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OIM89_RS23895	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OIM89_RS23900	COG0131	Imidazoleglycerol-phosphate dehydratase
OIM89_RS23910	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OIM89_RS23915	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
OIM89_RS23920	COG0251	oxidation-reduction process
OIM89_RS23925	COG0107	imidazoleglycerol-phosphate synthase activity
OIM89_RS23930	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OIM89_RS23940	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
OIM89_RS23950	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OIM89_RS23970	COG0134	indole-3-glycerol-phosphate synthase activity
OIM89_RS23975	COG0133	tryptophan synthase activity
OIM89_RS23980	COG0159	tryptophan synthase activity
OIM89_RS23990	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
OIM89_RS24000	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OIM89_RS24025	COG1397	ADP-ribosylglycohydrolase
OIM89_RS24035	COG0067	glutamate synthase
OIM89_RS24035	COG0070	glutamate synthase
OIM89_RS24035	COG0069	glutamate synthase activity
OIM89_RS24050	COG1278	Cold shock
OIM89_RS24055	COG0513	Belongs to the DEAD box helicase family
OIM89_RS24065	COG0287	Prephenate dehydrogenase
OIM89_RS24065	COG1605	Chorismate mutase
OIM89_RS24100	COG0737	Belongs to the 5'-nucleotidase family
OIM89_RS24140	COG0559	Belongs to the binding-protein-dependent transport system permease family
OIM89_RS24155	COG2050	protein possibly involved in aromatic compounds catabolism
OIM89_RS24175	COG1643	Atp-dependent helicase
OIM89_RS24180	COG2226	methyltransferase
OIM89_RS24200	COG0237	dephospho-CoA kinase activity
OIM89_RS24220	COG1288	antiporter activity
OIM89_RS24270	COG0477	Major facilitator Superfamily
OIM89_RS24275	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OIM89_RS24280	COG0584	glycerophosphoryl diester phosphodiesterase
OIM89_RS24290	COG0556	nucleotide-excision repair
OIM89_RS24310	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
OIM89_RS24315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OIM89_RS24325	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OIM89_RS24340	COG0322	excinuclease ABC activity
OIM89_RS24345	COG1660	Displays ATPase and GTPase activities
OIM89_RS24355	COG1481	regulation of sporulation
OIM89_RS24360	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OIM89_RS24365	COG0126	phosphoglycerate kinase activity
OIM89_RS24370	COG0149	triose-phosphate isomerase activity
OIM89_RS24375	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
OIM89_RS24385	COG0166	Belongs to the GPI family
OIM89_RS24390	COG0363	glucosamine-6-phosphate deaminase activity
OIM89_RS24405	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OIM89_RS24410	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OIM89_RS24415	COG0109	protoheme IX farnesyltransferase activity
OIM89_RS24440	COG1131	(ABC) transporter
OIM89_RS24455	COG0719	Fe-S assembly protein
OIM89_RS24465	COG0396	ATPase activity
OIM89_RS24470	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OIM89_RS24475	COG0822	iron-sulfur transferase activity
OIM89_RS24485	COG2171	N-acyltransferase activity
OIM89_RS24520	COG2197	response regulator
OIM89_RS24525	COG4585	Histidine kinase
OIM89_RS24555	COG1902	pentaerythritol trinitrate reductase activity
OIM89_RS24565	COG1917	Cupin 2, conserved barrel domain protein
OIM89_RS24575	COG0456	acetyltransferase
OIM89_RS24580	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
OIM89_RS24610	COG1797	cobyrinic acid a,c-diamide synthase activity
OIM89_RS24625	COG1492	cobalamin metabolic process
OIM89_RS24645	COG0235	Class ii aldolase
OIM89_RS24665	COG0488	(ABC) transporter
OIM89_RS24725	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OIM89_RS24750	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OIM89_RS24765	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OIM89_RS24770	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OIM89_RS24780	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
OIM89_RS24800	COG2261	transglycosylase associated protein
OIM89_RS24805	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OIM89_RS24815	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
OIM89_RS24825	COG2186	Transcriptional regulator
OIM89_RS24830	COG2807	transmembrane transport
OIM89_RS24850	COG0560	Phosphoserine phosphatase
OIM89_RS24850	COG3830	Belongs to the UPF0237 family
OIM89_RS24855	COG0842	Transport permease protein
OIM89_RS24855	COG1131	(ABC) transporter
OIM89_RS24855	COG1716	ATPase activity
OIM89_RS24880	COG2197	response regulator
OIM89_RS24895	COG1119	ATPase activity
OIM89_RS24915	COG1881	PFAM PEBP family protein
OIM89_RS24925	COG2094	Belongs to the DNA glycosylase MPG family
OIM89_RS24960	COG0647	UMP catabolic process
OIM89_RS24980	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OIM89_RS24985	COG0497	DNA recombination
OIM89_RS25000	COG0438	transferase activity, transferring glycosyl groups
OIM89_RS25020	COG3387	PFAM Glycoside hydrolase 15-related
OIM89_RS25025	COG0504	CTP synthase activity
OIM89_RS25030	COG0494	nUDIX hydrolase
OIM89_RS25040	COG0686	Belongs to the AlaDH PNT family
OIM89_RS25055	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
OIM89_RS25060	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OIM89_RS25065	COG1187	pseudouridine synthase activity
OIM89_RS25075	COG1397	ADP-ribosylglycohydrolase
OIM89_RS25080	COG3541	Predicted nucleotidyltransferase
OIM89_RS25095	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
OIM89_RS25105	COG1160	GTP binding
OIM89_RS25125	COG0438	transferase activity, transferring glycosyl groups
OIM89_RS25145	COG0671	phosphoesterase, PA-phosphatase related
OIM89_RS25155	COG0477	Major facilitator Superfamily
OIM89_RS25160	COG1799	cell septum assembly
OIM89_RS25175	COG0765	amino acid transport
OIM89_RS25190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OIM89_RS25210	COG0330	HflC and HflK could
OIM89_RS25225	COG0587	DNA-directed DNA polymerase activity
OIM89_RS25230	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OIM89_RS25300	COG1216	Glycosyl transferase, family 2
OIM89_RS25320	COG2755	lipolytic protein G-D-S-L family
OIM89_RS25340	COG3973	AAA domain
OIM89_RS25345	COG2188	Transcriptional regulator
OIM89_RS25350	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
OIM89_RS25360	COG1309	transcriptional regulator
OIM89_RS25410	COG3876	Protein conserved in bacteria
OIM89_RS25420	COG0488	(ABC) transporter
OIM89_RS25425	COG0110	maltose O-acetyltransferase activity
OIM89_RS25435	COG0318	PFAM AMP-dependent synthetase and ligase
OIM89_RS25445	COG1960	acyl-CoA dehydrogenase activity
OIM89_RS25465	COG2149	membrane
OIM89_RS25470	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
OIM89_RS25510	COG3265	gluconokinase activity
OIM89_RS25520	COG3012	SEC-C Motif Domain Protein
OIM89_RS25525	COG3189	MarR family transcriptional regulator
OIM89_RS25535	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OIM89_RS25570	COG0667	Aldo Keto reductase
OIM89_RS25575	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OIM89_RS25585	COG0598	Magnesium transport protein CorA
OIM89_RS25605	COG0215	cysteine-tRNA ligase activity
OIM89_RS25620	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
OIM89_RS25625	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OIM89_RS25630	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
OIM89_RS25640	COG0646	methionine synthase
OIM89_RS25640	COG1410	methionine synthase
OIM89_RS25650	COG4166	transmembrane transport
OIM89_RS25655	COG2197	response regulator
OIM89_RS25665	COG1994	Peptidase M50
OIM89_RS25665	COG0517	IMP dehydrogenase activity
OIM89_RS25685	COG1222	aaa ATPase
OIM89_RS25690	COG4122	O-methyltransferase activity
OIM89_RS25700	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
OIM89_RS25705	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
OIM89_RS25720	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
OIM89_RS25755	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OIM89_RS25760	COG0805	protein transport
OIM89_RS25775	COG2124	cytochrome p450
OIM89_RS25805	COG0564	pseudouridine synthase activity
OIM89_RS25825	COG1595	DNA-templated transcription, initiation
OIM89_RS25835	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OIM89_RS25840	COG4175	Glycine betaine
OIM89_RS25840	COG0517	IMP dehydrogenase activity
OIM89_RS25865	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
OIM89_RS25870	COG0531	amino acid
OIM89_RS25875	COG2186	Transcriptional regulator
OIM89_RS25880	COG0174	glutamine synthetase
OIM89_RS25885	COG1012	belongs to the aldehyde dehydrogenase family
OIM89_RS25920	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
OIM89_RS25930	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
OIM89_RS25935	COG0291	Belongs to the bacterial ribosomal protein bL35 family
OIM89_RS25940	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
OIM89_RS25945	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OIM89_RS25955	COG5002	protein histidine kinase activity
OIM89_RS25960	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
OIM89_RS25965	COG0072	phenylalanine-tRNA ligase activity
OIM89_RS25965	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OIM89_RS26000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OIM89_RS26020	COG0426	domain, Protein
OIM89_RS26020	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIM89_RS26050	COG0667	Aldo Keto reductase
OIM89_RS26090	COG0537	adenosine 5'-monophosphoramidase activity
OIM89_RS26105	COG2249	NAD(P)H dehydrogenase (quinone) activity
OIM89_RS26120	COG1028	Short-chain dehydrogenase reductase Sdr
OIM89_RS26140	COG0697	spore germination
OIM89_RS26145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OIM89_RS26180	COG2838	Isocitrate dehydrogenase
OIM89_RS26200	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OIM89_RS26215	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
OIM89_RS26220	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
OIM89_RS26225	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
OIM89_RS26230	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OIM89_RS26235	COG1438	arginine binding
OIM89_RS26240	COG4585	Histidine kinase
OIM89_RS26245	COG2197	response regulator
OIM89_RS26255	COG2409	Drug exporters of the RND superfamily
OIM89_RS26260	COG0385	Bile acid
OIM89_RS26270	COG0165	Argininosuccinate lyase
OIM89_RS26290	COG0477	Major facilitator Superfamily
OIM89_RS26295	COG0318	PFAM AMP-dependent synthetase and ligase
OIM89_RS26295	COG0204	Acyl-transferase
OIM89_RS26300	COG0584	glycerophosphoryl diester phosphodiesterase
OIM89_RS26325	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OIM89_RS26330	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OIM89_RS26335	COG2011	ABC-type metal ion transport system permease component
OIM89_RS26340	COG1464	Belongs to the NlpA lipoprotein family
OIM89_RS26345	COG1464	Belongs to the NlpA lipoprotein family
OIM89_RS26360	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
OIM89_RS26365	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OIM89_RS26365	COG1648	precorrin-2 dehydrogenase activity
OIM89_RS26440	COG0456	acetyltransferase
OIM89_RS26500	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OIM89_RS26505	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OIM89_RS26520	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OIM89_RS26525	COG1560	Kdo2-lipid A biosynthetic process
OIM89_RS26530	COG0438	transferase activity, transferring glycosyl groups
OIM89_RS26540	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
OIM89_RS26545	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
OIM89_RS26550	COG0217	transcriptional regulatory protein
OIM89_RS26555	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
OIM89_RS26560	COG0632	four-way junction helicase activity
OIM89_RS26565	COG2255	four-way junction helicase activity
OIM89_RS26575	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OIM89_RS26580	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OIM89_RS26585	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OIM89_RS26590	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OIM89_RS26600	COG1196	nuclear chromosome segregation
OIM89_RS26605	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OIM89_RS26615	COG0124	histidyl-tRNA synthetase
OIM89_RS26630	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
OIM89_RS26645	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OIM89_RS26650	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OIM89_RS26655	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OIM89_RS26660	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OIM89_RS26665	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
OIM89_RS26670	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OIM89_RS26675	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
OIM89_RS26685	COG0006	proline dipeptidase activity
OIM89_RS26690	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OIM89_RS26695	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OIM89_RS26705	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
OIM89_RS26710	COG0540	Belongs to the ATCase OTCase family
OIM89_RS26715	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
OIM89_RS26725	COG0505	Belongs to the CarA family
OIM89_RS26730	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
OIM89_RS26735	COG0167	dihydroorotate dehydrogenase activity
OIM89_RS26740	COG0284	orotidine-5'-phosphate decarboxylase activity
OIM89_RS26755	COG1758	RNA polymerase activity
OIM89_RS26765	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OIM89_RS26800	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OIM89_RS26815	COG2318	DinB family
OIM89_RS26820	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
OIM89_RS26825	COG2390	Transcriptional regulator
OIM89_RS26865	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OIM89_RS26885	COG0697	spore germination
OIM89_RS26890	COG2233	PERMEase
OIM89_RS26900	COG0738	Major facilitator superfamily
OIM89_RS26905	COG1846	Transcriptional regulator
OIM89_RS26905	COG1940	carbohydrate kinase activity
OIM89_RS26910	COG1090	epimerase
OIM89_RS26925	COG3201	nicotinamide mononucleotide transporter
OIM89_RS26930	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OIM89_RS26930	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OIM89_RS26935	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
OIM89_RS26940	COG0140	phosphoribosyl-ATP diphosphatase activity
OIM89_RS26945	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
OIM89_RS26975	COG1960	acyl-CoA dehydrogenase activity
OIM89_RS26995	COG0463	Glycosyl transferase, family 2
OIM89_RS27010	COG2270	Major facilitator Superfamily
OIM89_RS27020	COG2364	Membrane
OIM89_RS27025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OIM89_RS27110	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
OIM89_RS27130	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OIM89_RS27140	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OIM89_RS27170	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
OIM89_RS27190	COG1716	ATPase activity
OIM89_RS27210	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OIM89_RS27220	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OIM89_RS27220	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OIM89_RS27275	COG0697	spore germination
OIM89_RS27290	COG0697	spore germination
OIM89_RS27310	COG4251	negative regulation of phosphorylation
OIM89_RS27360	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
OIM89_RS27390	COG0815	Transfers the fatty acyl group on membrane lipoproteins
OIM89_RS27410	COG1982	Orn Lys Arg decarboxylase major
OIM89_RS27420	COG1968	undecaprenyl-diphosphatase activity
OIM89_RS27440	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OIM89_RS27495	COG0110	maltose O-acetyltransferase activity
OIM89_RS27505	COG1832	CoA-binding protein
OIM89_RS27510	COG1739	Uncharacterized protein family UPF0029
OIM89_RS27530	COG1595	DNA-templated transcription, initiation
OIM89_RS27545	COG0420	3'-5' exonuclease activity
OIM89_RS27550	COG0419	ATPase involved in DNA repair
OIM89_RS27555	COG1522	sequence-specific DNA binding
OIM89_RS27565	COG1028	Short-chain dehydrogenase reductase Sdr
OIM89_RS27580	COG0626	cystathionine gamma-synthase activity
OIM89_RS27605	COG2188	Transcriptional regulator
OIM89_RS27610	COG1940	carbohydrate kinase activity
OIM89_RS27630	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OIM89_RS27660	COG0456	acetyltransferase
OIM89_RS27665	COG0488	(ABC) transporter
OIM89_RS27670	COG0488	(ABC) transporter
OIM89_RS27680	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
OIM89_RS27685	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
OIM89_RS27690	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
OIM89_RS27720	COG0740	serine-type endopeptidase activity
OIM89_RS27730	COG0831	urea catabolic process
OIM89_RS27735	COG0832	Belongs to the urease beta subunit family
OIM89_RS27740	COG0804	urea catabolic process
OIM89_RS27750	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
OIM89_RS27755	COG0829	nickel cation binding
OIM89_RS27760	COG4552	Acetyltransferase involved in intracellular survival and related
OIM89_RS27765	COG0204	Acyl-transferase
OIM89_RS27795	COG1132	(ABC) transporter
OIM89_RS27810	COG2175	clavaminate synthase activity
OIM89_RS27815	COG0477	Major facilitator Superfamily
OIM89_RS27820	COG0435	Glutathione S-transferase
OIM89_RS27825	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
OIM89_RS27825	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
OIM89_RS27840	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OIM89_RS27845	COG0583	DNA-binding transcription factor activity
OIM89_RS27870	COG0205	6-phosphofructokinase activity
OIM89_RS27875	COG3442	glutamine amidotransferase
OIM89_RS27885	COG0242	peptide deformylase activity
OIM89_RS27895	COG1960	acyl-CoA dehydrogenase activity
OIM89_RS27915	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OIM89_RS27940	COG1175	transmembrane transport
OIM89_RS27945	COG0395	ABC-type sugar transport system, permease component
OIM89_RS27950	COG2723	6-phospho-beta-galactosidase activity
OIM89_RS27955	COG0501	Belongs to the peptidase M48B family
OIM89_RS28005	COG4251	negative regulation of phosphorylation
OIM89_RS28010	COG0784	Response regulator, receiver
OIM89_RS28030	COG0656	L-ascorbic acid biosynthetic process
OIM89_RS28040	COG1595	DNA-templated transcription, initiation
OIM89_RS28050	COG1132	(ABC) transporter
OIM89_RS28070	COG3693	PFAM glycoside hydrolase, family 10
OIM89_RS28080	COG1309	transcriptional regulator
OIM89_RS28085	COG1131	(ABC) transporter
OIM89_RS28090	COG3559	Exporter of polyketide antibiotics
OIM89_RS28100	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
OIM89_RS28135	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
OIM89_RS28140	COG3279	Response regulator of the LytR AlgR family
OIM89_RS28150	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OIM89_RS28155	COG3275	phosphorelay sensor kinase activity
OIM89_RS28220	COG0583	DNA-binding transcription factor activity
OIM89_RS28230	COG1053	succinate dehydrogenase
OIM89_RS28235	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OIM89_RS28240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OIM89_RS28250	COG3360	Dodecin
OIM89_RS28255	COG2182	Extracellular solute-binding protein
OIM89_RS28260	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
OIM89_RS28265	COG0121	glutamine amidotransferase
OIM89_RS28270	COG1262	PFAM Formylglycine-generating sulfatase enzyme
OIM89_RS28290	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OIM89_RS28295	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OIM89_RS28300	COG1959	2 iron, 2 sulfur cluster binding
OIM89_RS28305	COG1028	Short-chain dehydrogenase reductase Sdr
OIM89_RS28325	COG2837	iron assimilation
OIM89_RS28335	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
OIM89_RS28335	COG1796	DNA polymerase
OIM89_RS28340	COG0142	geranyltranstransferase activity
OIM89_RS28370	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
OIM89_RS28380	COG2310	stress, protein
OIM89_RS28395	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OIM89_RS28405	COG0254	rRNA binding
OIM89_RS28410	COG0267	Belongs to the bacterial ribosomal protein bL33 family
OIM89_RS28415	COG0227	Belongs to the bacterial ribosomal protein bL28 family
OIM89_RS28420	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OIM89_RS28500	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
OIM89_RS28505	COG4948	Mandelate Racemase Muconate Lactonizing
OIM89_RS28545	COG4257	antibiotic catabolic process
OIM89_RS28555	COG0803	Belongs to the bacterial solute-binding protein 9 family
OIM89_RS28565	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OIM89_RS28570	COG1121	(ABC) transporter
OIM89_RS28575	COG4608	Belongs to the ABC transporter superfamily
OIM89_RS28580	COG0444	Belongs to the ABC transporter superfamily
OIM89_RS28590	COG0747	negative chemotaxis
OIM89_RS28600	COG3458	cephalosporin-C deacetylase activity
OIM89_RS28610	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OIM89_RS28620	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
OIM89_RS28625	COG0363	glucosamine-6-phosphate deaminase activity
OIM89_RS28630	COG0590	tRNA wobble adenosine to inosine editing
OIM89_RS28635	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OIM89_RS28665	COG2201	protein-glutamate methylesterase activity
OIM89_RS28670	COG0300	oxidoreductase activity
OIM89_RS28680	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OIM89_RS28725	COG0745	RESPONSE REGULATOR receiver
OIM89_RS28730	COG0243	molybdopterin cofactor binding
OIM89_RS28735	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OIM89_RS28740	COG2146	nitrite reductase [NAD(P)H] activity
OIM89_RS28740	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OIM89_RS28790	COG2188	Transcriptional regulator
OIM89_RS28795	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
OIM89_RS28800	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
OIM89_RS28805	COG1984	allophanate hydrolase subunit 2
OIM89_RS28825	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OIM89_RS28830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OIM89_RS28835	COG1120	ATPase activity
OIM89_RS28865	COG1132	(ABC) transporter
OIM89_RS28870	COG1132	(ABC) transporter
OIM89_RS28875	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OIM89_RS28885	COG0110	maltose O-acetyltransferase activity
OIM89_RS28905	COG0494	nUDIX hydrolase
OIM89_RS28920	COG3395	kinase activity
OIM89_RS28925	COG0235	Class ii aldolase
OIM89_RS28945	COG1116	anion transmembrane transporter activity
OIM89_RS28955	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OIM89_RS28965	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OIM89_RS28970	COG0583	DNA-binding transcription factor activity
OIM89_RS28980	COG1028	Short-chain dehydrogenase reductase Sdr
OIM89_RS29000	COG2124	cytochrome p450
OIM89_RS29005	COG1174	glycine betaine transport
OIM89_RS29010	COG1174	glycine betaine transport
OIM89_RS29020	COG0517	IMP dehydrogenase activity
OIM89_RS29020	COG1125	glycine betaine transport
OIM89_RS29045	COG1960	acyl-CoA dehydrogenase activity
OIM89_RS29050	COG1960	acyl-CoA dehydrogenase activity
OIM89_RS29060	COG0601	transmembrane transport
OIM89_RS29065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OIM89_RS29070	COG0444	Belongs to the ABC transporter superfamily
OIM89_RS29075	COG1124	(ABC) transporter
OIM89_RS29095	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
OIM89_RS29100	COG2318	DinB family
OIM89_RS29165	COG1028	Short-chain dehydrogenase reductase Sdr
OIM89_RS29215	COG3321	synthase
OIM89_RS29215	COG0604	alcohol dehydrogenase
OIM89_RS29245	COG3321	synthase
OIM89_RS29245	COG0604	alcohol dehydrogenase
OIM89_RS29270	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
OIM89_RS29305	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OIM89_RS29315	COG1129	ABC transporter
OIM89_RS29345	COG3483	tryptophan 2,3-dioxygenase activity
OIM89_RS29350	COG1028	Short-chain dehydrogenase reductase Sdr
OIM89_RS29355	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIM89_RS29360	COG2151	metal-sulfur cluster biosynthetic enzyme
OIM89_RS29365	COG3396	Phenylacetate-CoA oxygenase
OIM89_RS29375	COG3396	Phenylacetate-CoA oxygenase
OIM89_RS29390	COG0604	alcohol dehydrogenase
OIM89_RS29400	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OIM89_RS29445	COG0515	serine threonine protein kinase
OIM89_RS29480	COG1404	Belongs to the peptidase S8 family
OIM89_RS29525	COG3321	synthase
OIM89_RS29525	COG0300	oxidoreductase activity
OIM89_RS29525	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OIM89_RS29525	COG4221	oxidoreductase activity
OIM89_RS29535	COG4335	DNA alkylation repair
OIM89_RS29560	COG0477	Major facilitator Superfamily
OIM89_RS29585	COG1309	transcriptional regulator
OIM89_RS29590	COG3246	L-lysine catabolic process to acetate
OIM89_RS29595	COG1250	3-hydroxyacyl-CoA dehydrogenase
OIM89_RS29620	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OIM89_RS29630	COG1396	sequence-specific DNA binding
OIM89_RS29640	COG2318	DinB family
OIM89_RS29665	COG2801	Transposase and inactivated derivatives
OIM89_RS29665	COG3415	Transposase
OIM89_RS29670	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OIM89_RS29685	COG1250	3-hydroxyacyl-CoA dehydrogenase
OIM89_RS29690	COG0604	alcohol dehydrogenase
OIM89_RS29695	COG3293	Transposase
OIM89_RS29810	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OIM89_RS29815	COG0142	geranyltranstransferase activity
OIM89_RS29820	COG1028	Short-chain dehydrogenase reductase Sdr
OIM89_RS29820	COG0604	alcohol dehydrogenase
OIM89_RS29820	COG3321	synthase