locus-tag	class	description
LJA35_RS00075	COG2223	nitrite transmembrane transporter activity
LJA35_RS00080	COG2207	Transcriptional regulator
LJA35_RS00090	COG3655	Transcriptional regulator
LJA35_RS00095	COG0644	oxidoreductase
LJA35_RS00140	COG1819	glycosyl
LJA35_RS00145	COG0789	Transcriptional regulator
LJA35_RS00150	COG1051	belongs to the nudix hydrolase family
LJA35_RS00220	COG0243	molybdopterin cofactor binding
LJA35_RS00240	COG0542	response to heat
LJA35_RS00260	COG0483	inositol monophosphate 1-phosphatase activity
LJA35_RS00270	COG3226	Transcriptional regulator
LJA35_RS00275	COG0738	Major facilitator superfamily
LJA35_RS00295	COG0583	DNA-binding transcription factor activity
LJA35_RS00315	COG0583	DNA-binding transcription factor activity
LJA35_RS00335	COG0531	amino acid
LJA35_RS00365	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LJA35_RS00375	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LJA35_RS00380	COG3387	PFAM Glycoside hydrolase 15-related
LJA35_RS00385	COG0589	response to stress
LJA35_RS00390	COG0129	dihydroxy-acid dehydratase activity
LJA35_RS00400	COG1278	Cold shock
LJA35_RS00405	COG1132	(ABC) transporter
LJA35_RS00425	COG0753	catalase activity
LJA35_RS00435	COG2249	NAD(P)H dehydrogenase (quinone) activity
LJA35_RS00450	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LJA35_RS00505	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LJA35_RS00520	COG4310	Domain of unknown function (DUF2172)
LJA35_RS00530	COG1215	transferase activity, transferring glycosyl groups
LJA35_RS00540	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
LJA35_RS00545	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LJA35_RS00575	COG2226	methyltransferase
LJA35_RS00580	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LJA35_RS00630	COG0604	alcohol dehydrogenase
LJA35_RS00630	COG1028	Short-chain dehydrogenase reductase Sdr
LJA35_RS00630	COG3321	synthase
LJA35_RS00635	COG0460	homoserine dehydrogenase
LJA35_RS00665	COG0667	Aldo Keto reductase
LJA35_RS00690	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
LJA35_RS00705	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LJA35_RS00715	COG1984	allophanate hydrolase subunit 2
LJA35_RS00750	COG0477	Major facilitator Superfamily
LJA35_RS00770	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LJA35_RS00780	COG1175	transmembrane transport
LJA35_RS00785	COG0395	ABC-type sugar transport system, permease component
LJA35_RS00790	COG1609	Transcriptional regulator
LJA35_RS00820	COG3290	protein histidine kinase activity
LJA35_RS00830	COG0346	lactoylglutathione lyase activity
LJA35_RS00835	COG0789	Transcriptional regulator
LJA35_RS00840	COG0659	secondary active sulfate transmembrane transporter activity
LJA35_RS00850	COG0483	inositol monophosphate 1-phosphatase activity
LJA35_RS00895	COG2382	esterase
LJA35_RS00905	COG1132	(ABC) transporter
LJA35_RS00915	COG1132	(ABC) transporter
LJA35_RS00925	COG1120	ATPase activity
LJA35_RS00930	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LJA35_RS00935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LJA35_RS00940	COG3486	L-lysine 6-monooxygenase (NADPH) activity
LJA35_RS00955	COG2936	dipeptidyl-peptidase activity
LJA35_RS00965	COG0513	Belongs to the DEAD box helicase family
LJA35_RS00975	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LJA35_RS00980	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LJA35_RS00990	COG0666	response to abiotic stimulus
LJA35_RS01040	COG1140	nitrate reductase beta subunit
LJA35_RS01050	COG2181	nitrate reductase activity
LJA35_RS01070	COG1278	Cold shock
LJA35_RS01080	COG0673	inositol 2-dehydrogenase activity
LJA35_RS01085	COG2188	Transcriptional regulator
LJA35_RS01120	COG0395	ABC-type sugar transport system, permease component
LJA35_RS01125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LJA35_RS01140	COG0739	heme binding
LJA35_RS01160	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LJA35_RS01165	COG3321	synthase
LJA35_RS01165	COG0604	alcohol dehydrogenase
LJA35_RS01170	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LJA35_RS01175	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LJA35_RS01180	COG2340	Cysteine-rich secretory protein family
LJA35_RS01185	COG2205	protein histidine kinase activity
LJA35_RS01190	COG0745	RESPONSE REGULATOR receiver
LJA35_RS01220	COG0789	Transcriptional regulator
LJA35_RS01235	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
LJA35_RS01260	COG0142	geranyltranstransferase activity
LJA35_RS01265	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LJA35_RS01270	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LJA35_RS01275	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LJA35_RS01280	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LJA35_RS01285	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LJA35_RS01300	COG3340	Belongs to the peptidase S51 family
LJA35_RS01305	COG2124	cytochrome p450
LJA35_RS01325	COG2018	Roadblock/LC7 domain
LJA35_RS01350	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
LJA35_RS01355	COG0655	NAD(P)H dehydrogenase (quinone) activity
LJA35_RS01360	COG0783	Belongs to the Dps family
LJA35_RS01380	COG1191	sigma factor activity
LJA35_RS01385	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
LJA35_RS01410	COG0505	Belongs to the CarA family
LJA35_RS01445	COG2235	arginine
LJA35_RS01465	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
LJA35_RS01480	COG1937	Protein conserved in bacteria
LJA35_RS01485	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LJA35_RS01520	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LJA35_RS01535	COG1595	DNA-templated transcription, initiation
LJA35_RS01550	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LJA35_RS01555	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LJA35_RS01575	COG0488	(ABC) transporter
LJA35_RS01585	COG1120	ATPase activity
LJA35_RS01590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LJA35_RS01620	COG3397	chitin binding
LJA35_RS01640	COG1028	Short-chain dehydrogenase reductase Sdr
LJA35_RS01645	COG2264	protein methyltransferase activity
LJA35_RS01710	COG1175	transmembrane transport
LJA35_RS01715	COG0395	ABC-type sugar transport system, permease component
LJA35_RS01720	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LJA35_RS01745	COG0277	FAD linked oxidase domain protein
LJA35_RS01785	COG3290	protein histidine kinase activity
LJA35_RS01805	COG0477	Major facilitator Superfamily
LJA35_RS01835	COG1295	ribonuclease BN
LJA35_RS01840	COG1028	Short-chain dehydrogenase reductase Sdr
LJA35_RS01855	COG2080	2 iron, 2 sulfur cluster binding
LJA35_RS01860	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
LJA35_RS01865	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LJA35_RS01910	COG1132	(ABC) transporter
LJA35_RS01960	COG0410	ABC transporter
LJA35_RS01965	COG2508	Transcriptional regulator
LJA35_RS01970	COG2197	response regulator
LJA35_RS01980	COG0673	inositol 2-dehydrogenase activity
LJA35_RS02060	COG1309	transcriptional regulator
LJA35_RS02090	COG1846	Transcriptional regulator
LJA35_RS02090	COG1940	carbohydrate kinase activity
LJA35_RS02095	COG1175	transmembrane transport
LJA35_RS02120	COG1028	Short-chain dehydrogenase reductase Sdr
LJA35_RS02140	COG1132	(ABC) transporter
LJA35_RS02195	COG0517	IMP dehydrogenase activity
LJA35_RS02225	COG2274	protein secretion by the type I secretion system
LJA35_RS02230	COG0248	Ppx GppA phosphatase
LJA35_RS02245	COG2890	protein-(glutamine-N5) methyltransferase activity
LJA35_RS02260	COG1304	FMN binding
LJA35_RS02275	COG3250	beta-galactosidase activity
LJA35_RS02290	COG0667	Aldo Keto reductase
LJA35_RS02305	COG2124	cytochrome p450
LJA35_RS02320	COG0435	Glutathione S-transferase
LJA35_RS02350	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LJA35_RS02365	COG1007	ATP synthesis coupled electron transport
LJA35_RS02370	COG1006	Multisubunit Na H antiporter MnhC subunit
LJA35_RS02410	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LJA35_RS02410	COG1796	DNA polymerase
LJA35_RS02455	COG2706	6-phosphogluconolactonase activity
LJA35_RS02475	COG1357	PFAM Pentapeptide repeats (8 copies)
LJA35_RS02480	COG1595	DNA-templated transcription, initiation
LJA35_RS02495	COG1609	Transcriptional regulator
LJA35_RS02515	COG1172	Belongs to the binding-protein-dependent transport system permease family
LJA35_RS02520	COG1129	ABC transporter
LJA35_RS02525	COG4952	isomerase
LJA35_RS02530	COG1028	Short-chain dehydrogenase reductase Sdr
LJA35_RS02530	COG3347	Dehydrogenase
LJA35_RS02535	COG1070	Carbohydrate kinase
LJA35_RS02540	COG0247	lactate metabolic process
LJA35_RS02545	COG1139	Iron-sulfur cluster binding protein
LJA35_RS02550	COG1556	Lactate utilization protein
LJA35_RS02555	COG0577	efflux transmembrane transporter activity
LJA35_RS02555	COG1136	(ABC) transporter
LJA35_RS02590	COG3540	Alkaline phosphatase
LJA35_RS02630	COG0668	transmembrane transport
LJA35_RS02645	COG2409	Drug exporters of the RND superfamily
LJA35_RS02650	COG1846	Transcriptional regulator
LJA35_RS02655	COG0702	epimerase
LJA35_RS02685	COG0604	alcohol dehydrogenase
LJA35_RS02715	COG1175	transmembrane transport
LJA35_RS02720	COG0395	ABC-type sugar transport system, permease component
LJA35_RS02725	COG1609	Transcriptional regulator
LJA35_RS02745	COG0800	Aldolase
LJA35_RS02760	COG0657	acetylesterase activity
LJA35_RS02795	COG0242	peptide deformylase activity
LJA35_RS02800	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LJA35_RS02805	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LJA35_RS02810	COG1609	Transcriptional regulator
LJA35_RS02825	COG0583	DNA-binding transcription factor activity
LJA35_RS02845	COG3976	FMN-binding domain protein
LJA35_RS02845	COG1053	succinate dehydrogenase
LJA35_RS02850	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LJA35_RS02860	COG0517	IMP dehydrogenase activity
LJA35_RS02875	COG0596	Alpha beta hydrolase
LJA35_RS02910	COG3572	ergothioneine biosynthetic process
LJA35_RS02915	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LJA35_RS02920	COG0121	glutamine amidotransferase
LJA35_RS02925	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
LJA35_RS02930	COG2182	Extracellular solute-binding protein
LJA35_RS02935	COG3360	Dodecin
LJA35_RS02945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LJA35_RS02970	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LJA35_RS02975	COG1053	succinate dehydrogenase
LJA35_RS02985	COG0583	DNA-binding transcription factor activity
LJA35_RS02995	COG0583	DNA-binding transcription factor activity
LJA35_RS03035	COG0726	polysaccharide deacetylase
LJA35_RS03045	COG0531	amino acid
LJA35_RS03050	COG2267	carboxylic ester hydrolase activity
LJA35_RS03080	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LJA35_RS03105	COG0395	ABC-type sugar transport system, permease component
LJA35_RS03110	COG1175	transmembrane transport
LJA35_RS03120	COG1609	Transcriptional regulator
LJA35_RS03155	COG3537	Alpha-1,2-mannosidase
LJA35_RS03170	COG0297	glycogen (starch) synthase activity
LJA35_RS03190	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LJA35_RS03205	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LJA35_RS03385	COG0159	tryptophan synthase activity
LJA35_RS03430	COG0084	hydrolase, TatD family'
LJA35_RS03455	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LJA35_RS03475	COG3291	Pkd domain containing protein
LJA35_RS03505	COG2409	Drug exporters of the RND superfamily
LJA35_RS03580	COG2217	Heavy metal translocating P-type atpase
LJA35_RS03590	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LJA35_RS03660	COG4109	DRTGG domain
LJA35_RS03705	COG0574	Belongs to the PEP-utilizing enzyme family
LJA35_RS03705	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LJA35_RS03715	COG1063	alcohol dehydrogenase
LJA35_RS03725	COG0589	response to stress
LJA35_RS03755	COG0745	RESPONSE REGULATOR receiver
LJA35_RS03760	COG2205	protein histidine kinase activity
LJA35_RS03780	COG0702	epimerase
LJA35_RS03790	COG3046	protein related to deoxyribodipyrimidine photolyase
LJA35_RS03795	COG0142	geranyltranstransferase activity
LJA35_RS03815	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
LJA35_RS03895	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LJA35_RS04040	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LJA35_RS04075	COG4585	Histidine kinase
LJA35_RS04080	COG2201	protein-glutamate methylesterase activity
LJA35_RS04090	COG1012	belongs to the aldehyde dehydrogenase family
LJA35_RS04135	COG1169	isochorismate synthase
LJA35_RS04140	COG1132	(ABC) transporter
LJA35_RS04145	COG1132	(ABC) transporter
LJA35_RS04145	COG2375	cellular response to nickel ion
LJA35_RS04150	COG4106	trans-aconitate 2-methyltransferase activity
LJA35_RS04155	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
LJA35_RS04160	COG2124	cytochrome p450
LJA35_RS04175	COG2226	methyltransferase
LJA35_RS04175	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LJA35_RS04175	COG3433	isochorismatase activity
LJA35_RS04180	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
LJA35_RS04180	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LJA35_RS04185	COG1021	2,3-dihydroxybenzoate-AMP ligase
LJA35_RS04190	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LJA35_RS04200	COG4171	peptide transport system, permease
LJA35_RS04205	COG0601	transmembrane transport
LJA35_RS04230	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LJA35_RS04235	COG1120	ATPase activity
LJA35_RS04240	COG1609	Transcriptional regulator
LJA35_RS04250	COG0402	S-adenosylhomocysteine deaminase activity
LJA35_RS04255	COG2233	PERMEase
LJA35_RS04300	COG0366	Alpha amylase catalytic
LJA35_RS04300	COG1874	Beta-galactosidase
LJA35_RS04325	COG1653	transport
LJA35_RS04330	COG1175	transmembrane transport
LJA35_RS04335	COG0395	ABC-type sugar transport system, permease component
LJA35_RS04340	COG0366	Alpha amylase catalytic
LJA35_RS04350	COG1132	(ABC) transporter
LJA35_RS04370	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LJA35_RS04380	COG0531	amino acid
LJA35_RS04385	COG0668	transmembrane transport
LJA35_RS04390	COG2838	Isocitrate dehydrogenase
LJA35_RS04405	COG2124	cytochrome p450
LJA35_RS04420	COG1404	Belongs to the peptidase S8 family
LJA35_RS04430	COG2197	response regulator
LJA35_RS04445	COG0385	Bile acid
LJA35_RS04450	COG2814	Major facilitator Superfamily
LJA35_RS04465	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LJA35_RS04470	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LJA35_RS04475	COG2186	Transcriptional regulator
LJA35_RS04480	COG0673	inositol 2-dehydrogenase activity
LJA35_RS04485	COG3548	integral membrane protein
LJA35_RS04490	COG1609	Transcriptional regulator
LJA35_RS04500	COG0673	inositol 2-dehydrogenase activity
LJA35_RS04505	COG2764	glyoxalase bleomycin resistance protein dioxygenase
LJA35_RS04530	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LJA35_RS04540	COG3718	enzyme involved in inositol metabolism
LJA35_RS04545	COG3962	Belongs to the TPP enzyme family
LJA35_RS04550	COG2188	Transcriptional regulator
LJA35_RS04600	COG0318	PFAM AMP-dependent synthetase and ligase
LJA35_RS04605	COG0183	Belongs to the thiolase family
LJA35_RS04610	COG2267	carboxylic ester hydrolase activity
LJA35_RS04635	COG0174	glutamine synthetase
LJA35_RS04650	COG1320	monovalent cation:proton antiporter activity
LJA35_RS04665	COG0651	ATP synthesis coupled electron transport
LJA35_RS04670	COG1006	Multisubunit Na H antiporter MnhC subunit
LJA35_RS04675	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LJA35_RS04675	COG2111	Na H antiporter
LJA35_RS04705	COG0583	DNA-binding transcription factor activity
LJA35_RS04710	COG0156	8-amino-7-oxononanoate synthase activity
LJA35_RS04715	COG1063	alcohol dehydrogenase
LJA35_RS04760	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LJA35_RS04775	COG0179	Fumarylacetoacetate (FAA) hydrolase
LJA35_RS04795	COG2755	lipolytic protein G-D-S-L family
LJA35_RS04805	COG2365	Tyrosine phosphatase family
LJA35_RS04825	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LJA35_RS04830	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LJA35_RS04845	COG1657	PFAM Prenyltransferase squalene oxidase
LJA35_RS04855	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LJA35_RS04875	COG1562	ergosterol biosynthetic process
LJA35_RS04880	COG1134	teichoic acid transport
LJA35_RS04920	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
LJA35_RS04930	COG1024	Enoyl-CoA hydratase
LJA35_RS04950	COG2183	response to ionizing radiation
LJA35_RS04955	COG0488	(ABC) transporter
LJA35_RS04965	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LJA35_RS04980	COG1113	amino acid transport
LJA35_RS04990	COG1024	Enoyl-CoA hydratase
LJA35_RS04990	COG1250	3-hydroxyacyl-CoA dehydrogenase
LJA35_RS04995	COG0183	Belongs to the thiolase family
LJA35_RS05000	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LJA35_RS05005	COG3268	Saccharopine dehydrogenase
LJA35_RS05020	COG1515	deoxyribonuclease V activity
LJA35_RS05050	COG0488	(ABC) transporter
LJA35_RS05055	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LJA35_RS05060	COG1834	amidinotransferase
LJA35_RS05105	COG1793	dna ligase
LJA35_RS05115	COG1470	cell adhesion involved in biofilm formation
LJA35_RS05135	COG0183	Belongs to the thiolase family
LJA35_RS05140	COG3485	protocatechuate 3,4-dioxygenase
LJA35_RS05145	COG3485	protocatechuate 3,4-dioxygenase
LJA35_RS05150	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LJA35_RS05155	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LJA35_RS05185	COG3511	phospholipase C
LJA35_RS05190	COG0477	Major facilitator Superfamily
LJA35_RS05205	COG2197	response regulator
LJA35_RS05210	COG1132	(ABC) transporter
LJA35_RS05215	COG1132	(ABC) transporter
LJA35_RS05225	COG0515	serine threonine protein kinase
LJA35_RS05265	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LJA35_RS05275	COG1486	melibiose metabolic process
LJA35_RS05290	COG2197	response regulator
LJA35_RS05295	COG2409	Drug exporters of the RND superfamily
LJA35_RS05315	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LJA35_RS05330	COG0166	Belongs to the GPI family
LJA35_RS05335	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
LJA35_RS05350	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LJA35_RS05370	COG0297	glycogen (starch) synthase activity
LJA35_RS05385	COG1183	phosphatidylcholine synthase activity
LJA35_RS05395	COG1309	transcriptional regulator
LJA35_RS05410	COG0747	negative chemotaxis
LJA35_RS05430	COG0443	Heat shock 70 kDa protein
LJA35_RS05460	COG1196	nuclear chromosome segregation
LJA35_RS05525	COG0300	oxidoreductase activity
LJA35_RS05555	COG3340	Belongs to the peptidase S51 family
LJA35_RS05580	COG1733	regulation of RNA biosynthetic process
LJA35_RS05610	COG1733	regulation of RNA biosynthetic process
LJA35_RS05625	COG4632	Exopolysaccharide biosynthesis protein
LJA35_RS05625	COG5434	Belongs to the glycosyl hydrolase 28 family
LJA35_RS05645	COG2723	6-phospho-beta-galactosidase activity
LJA35_RS05650	COG0395	ABC-type sugar transport system, permease component
LJA35_RS05655	COG1175	transmembrane transport
LJA35_RS05660	COG2182	Extracellular solute-binding protein
LJA35_RS05665	COG1940	carbohydrate kinase activity
LJA35_RS05705	COG0129	dihydroxy-acid dehydratase activity
LJA35_RS05715	COG1472	Belongs to the glycosyl hydrolase 3 family
LJA35_RS05725	COG1175	transmembrane transport
LJA35_RS05735	COG1609	Transcriptional regulator
LJA35_RS05740	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LJA35_RS05755	COG1012	belongs to the aldehyde dehydrogenase family
LJA35_RS05765	COG0045	succinate-CoA ligase (ADP-forming) activity
LJA35_RS05775	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LJA35_RS05785	COG2223	nitrite transmembrane transporter activity
LJA35_RS05820	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LJA35_RS05840	COG0673	inositol 2-dehydrogenase activity
LJA35_RS05850	COG1172	Belongs to the binding-protein-dependent transport system permease family
LJA35_RS05855	COG1129	ABC transporter
LJA35_RS05870	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LJA35_RS05885	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LJA35_RS05890	COG3383	formate dehydrogenase (NAD+) activity
LJA35_RS05895	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LJA35_RS05905	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LJA35_RS05910	COG1846	Transcriptional regulator
LJA35_RS05935	COG0477	Major facilitator Superfamily
LJA35_RS05945	COG0656	L-ascorbic acid biosynthetic process
LJA35_RS05950	COG4221	oxidoreductase activity
LJA35_RS05955	COG2226	methyltransferase
LJA35_RS05960	COG5297	Belongs to the glycosyl hydrolase family 6
LJA35_RS05965	COG4733	cellulase activity
LJA35_RS05965	COG5297	Belongs to the glycosyl hydrolase family 6
LJA35_RS05980	COG3401	FG-GAP repeat protein
LJA35_RS05990	COG2154	pterin-4-alpha-carbinolamine dehydratase
LJA35_RS06020	COG1140	nitrate reductase beta subunit
LJA35_RS06055	COG0531	amino acid
LJA35_RS06110	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LJA35_RS06120	COG0693	protein deglycase activity
LJA35_RS06135	COG0488	(ABC) transporter
LJA35_RS06140	COG1597	lipid kinase activity
LJA35_RS06205	COG1793	dna ligase
LJA35_RS06205	COG3285	dna ligase
LJA35_RS06220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LJA35_RS06250	COG1619	proteins homologs of microcin C7 resistance protein MccF
LJA35_RS06260	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LJA35_RS06265	COG2362	D-Aminopeptidase
LJA35_RS06300	COG0596	Alpha beta hydrolase
LJA35_RS06335	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LJA35_RS06335	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LJA35_RS06340	COG2301	Belongs to the HpcH HpaI aldolase family
LJA35_RS06350	COG1960	acyl-CoA dehydrogenase activity
LJA35_RS06355	COG0688	phosphatidylethanolamine metabolic process
LJA35_RS06365	COG1929	Belongs to the glycerate kinase type-1 family
LJA35_RS06370	COG0494	nUDIX hydrolase
LJA35_RS06375	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LJA35_RS06385	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LJA35_RS06400	COG0640	Transcriptional regulator
LJA35_RS06420	COG0444	Belongs to the ABC transporter superfamily
LJA35_RS06425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LJA35_RS06430	COG0601	transmembrane transport
LJA35_RS06440	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
LJA35_RS06450	COG0483	inositol monophosphate 1-phosphatase activity
LJA35_RS06465	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
LJA35_RS06475	COG1012	belongs to the aldehyde dehydrogenase family
LJA35_RS06480	COG1891	lyase activity
LJA35_RS06490	COG4585	Histidine kinase
LJA35_RS06510	COG1953	Uracil, thiamine, allantoin
LJA35_RS06515	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LJA35_RS06520	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LJA35_RS06535	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LJA35_RS06560	COG0405	Gamma-glutamyltransferase
LJA35_RS06580	COG0577	efflux transmembrane transporter activity
LJA35_RS06585	COG0577	efflux transmembrane transporter activity
LJA35_RS06585	COG1136	(ABC) transporter
LJA35_RS06615	COG0154	amidase activity
LJA35_RS06630	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LJA35_RS06635	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LJA35_RS06665	COG1959	2 iron, 2 sulfur cluster binding
LJA35_RS06685	COG0494	nUDIX hydrolase
LJA35_RS06700	COG1090	epimerase
LJA35_RS06715	COG1595	DNA-templated transcription, initiation
LJA35_RS06720	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LJA35_RS06735	COG1231	oxidoreductase activity
LJA35_RS06740	COG1115	amino acid carrier protein
LJA35_RS06755	COG1032	radical SAM domain protein
LJA35_RS06760	COG0437	4 iron, 4 sulfur cluster binding
LJA35_RS06780	COG0709	Synthesizes selenophosphate from selenide and ATP
LJA35_RS06810	COG3246	L-lysine catabolic process to acetate
LJA35_RS06815	COG1250	3-hydroxyacyl-CoA dehydrogenase
LJA35_RS06825	COG0277	FAD linked oxidase domain protein
LJA35_RS06825	COG0247	lactate metabolic process
LJA35_RS06835	COG1132	(ABC) transporter
LJA35_RS06840	COG1802	Transcriptional regulator
LJA35_RS06845	COG3938	Belongs to the proline racemase family
LJA35_RS06850	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LJA35_RS06855	COG0446	pyridine nucleotide-disulphide oxidoreductase
LJA35_RS06865	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LJA35_RS06875	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LJA35_RS06885	COG1940	carbohydrate kinase activity
LJA35_RS06905	COG2188	Transcriptional regulator
LJA35_RS06915	COG2197	response regulator
LJA35_RS06935	COG1028	Short-chain dehydrogenase reductase Sdr
LJA35_RS06940	COG4266	Belongs to the allantoicase family
LJA35_RS06945	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LJA35_RS06950	COG1414	Transcriptional regulator
LJA35_RS06965	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LJA35_RS07000	COG1482	cell wall glycoprotein biosynthetic process
LJA35_RS07005	COG1940	carbohydrate kinase activity
LJA35_RS07010	COG1609	Transcriptional regulator
LJA35_RS07015	COG3250	beta-galactosidase activity
LJA35_RS07025	COG1175	transmembrane transport
LJA35_RS07030	COG3833	ABC-type maltose transport systems, permease component
LJA35_RS07040	COG0346	lactoylglutathione lyase activity
LJA35_RS07060	COG4264	IucA IucC family
LJA35_RS07085	COG0406	alpha-ribazole phosphatase activity
LJA35_RS07100	COG2233	PERMEase
LJA35_RS07110	COG2233	PERMEase
LJA35_RS07120	COG2351	hydroxyisourate hydrolase activity
LJA35_RS07140	COG3622	Belongs to the hyi family
LJA35_RS07145	COG2084	Dehydrogenase
LJA35_RS07150	COG0753	catalase activity
LJA35_RS07165	COG3960	tartronate-semialdehyde synthase activity
LJA35_RS07175	COG0318	PFAM AMP-dependent synthetase and ligase
LJA35_RS07180	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LJA35_RS07185	COG2197	response regulator
LJA35_RS07200	COG2319	Wd-40 repeat
LJA35_RS07200	COG4249	Peptidase C14 caspase catalytic subunit p20
LJA35_RS07240	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
LJA35_RS07240	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LJA35_RS07245	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LJA35_RS07250	COG0438	transferase activity, transferring glycosyl groups
LJA35_RS07260	COG0859	PFAM glycosyl transferase family 9
LJA35_RS07265	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LJA35_RS07275	COG2192	nodulation
LJA35_RS07300	COG2252	PERMEase
LJA35_RS07305	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LJA35_RS07320	COG3835	regulator
LJA35_RS07350	COG3851	Histidine kinase
LJA35_RS07355	COG2197	response regulator
LJA35_RS07365	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LJA35_RS07370	COG1802	Transcriptional regulator
LJA35_RS07390	COG0028	Belongs to the TPP enzyme family
LJA35_RS07410	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LJA35_RS07420	COG1162	GTPase activity
LJA35_RS07425	COG4585	Histidine kinase
LJA35_RS07430	COG2197	response regulator
LJA35_RS07445	COG1131	(ABC) transporter
LJA35_RS07455	COG0277	FAD linked oxidase domain protein
LJA35_RS07490	COG2197	response regulator
LJA35_RS07495	COG4585	Histidine kinase
LJA35_RS07505	COG2040	homocysteine
LJA35_RS07515	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LJA35_RS07520	COG0473	3-isopropylmalate dehydrogenase activity
LJA35_RS07520	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LJA35_RS07530	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LJA35_RS07535	COG0583	DNA-binding transcription factor activity
LJA35_RS07540	COG2814	Major facilitator Superfamily
LJA35_RS07545	COG1942	4-Oxalocrotonate Tautomerase
LJA35_RS07550	COG0583	DNA-binding transcription factor activity
LJA35_RS07580	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LJA35_RS07585	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LJA35_RS07590	COG1028	Short-chain dehydrogenase reductase Sdr
LJA35_RS07610	COG2814	Major facilitator Superfamily
LJA35_RS07625	COG0714	Associated with various cellular activities
LJA35_RS07640	COG2027	D-alanyl-D-alanine carboxypeptidase
LJA35_RS07700	COG3142	Participates in the control of copper homeostasis
LJA35_RS07710	COG1940	carbohydrate kinase activity
LJA35_RS07710	COG1846	Transcriptional regulator
LJA35_RS07745	COG1960	acyl-CoA dehydrogenase activity
LJA35_RS07765	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LJA35_RS07775	COG0175	sulfate reduction
LJA35_RS07780	COG0529	Catalyzes the synthesis of activated sulfate
LJA35_RS07805	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
LJA35_RS07810	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LJA35_RS07835	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LJA35_RS07900	COG2814	Major facilitator Superfamily
LJA35_RS07910	COG1181	Belongs to the D-alanine--D-alanine ligase family
LJA35_RS07915	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LJA35_RS07930	COG3173	Aminoglycoside phosphotransferase
LJA35_RS07940	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LJA35_RS07960	COG1309	transcriptional regulator
LJA35_RS07995	COG1174	glycine betaine transport
LJA35_RS08000	COG1174	glycine betaine transport
LJA35_RS08010	COG0745	RESPONSE REGULATOR receiver
LJA35_RS08015	COG2205	protein histidine kinase activity
LJA35_RS08020	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LJA35_RS08020	COG2226	methyltransferase
LJA35_RS08020	COG3433	isochorismatase activity
LJA35_RS08025	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LJA35_RS08105	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LJA35_RS08110	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LJA35_RS08130	COG0330	HflC and HflK could
LJA35_RS08140	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LJA35_RS08140	COG0723	plastoquinol--plastocyanin reductase activity
LJA35_RS08160	COG4152	abc transporter atp-binding protein
LJA35_RS08170	COG3220	belongs to the UPF0276 family
LJA35_RS08185	COG3253	May function as heme-dependent peroxidase
LJA35_RS08190	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LJA35_RS08200	COG0446	pyridine nucleotide-disulphide oxidoreductase
LJA35_RS08240	COG1472	Belongs to the glycosyl hydrolase 3 family
LJA35_RS08245	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LJA35_RS08260	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
LJA35_RS08265	COG0183	Belongs to the thiolase family
LJA35_RS08270	COG1250	3-hydroxyacyl-CoA dehydrogenase
LJA35_RS08270	COG1024	Enoyl-CoA hydratase
LJA35_RS08275	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LJA35_RS08280	COG0438	transferase activity, transferring glycosyl groups
LJA35_RS08290	COG0438	transferase activity, transferring glycosyl groups
LJA35_RS08295	COG0438	transferase activity, transferring glycosyl groups
LJA35_RS08300	COG1316	TRANSCRIPTIONal
LJA35_RS08320	COG0531	amino acid
LJA35_RS08325	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LJA35_RS08330	COG3979	chitinase
LJA35_RS08335	COG4214	carbohydrate transport
LJA35_RS08345	COG4213	ABC transporter substrate-binding protein
LJA35_RS08350	COG1940	carbohydrate kinase activity
LJA35_RS08355	COG0395	ABC-type sugar transport system, permease component
LJA35_RS08360	COG1175	transmembrane transport
LJA35_RS08365	COG1653	transport
LJA35_RS08400	COG0395	ABC-type sugar transport system, permease component
LJA35_RS08405	COG4209	transmembrane transport
LJA35_RS08410	COG3458	cephalosporin-C deacetylase activity
LJA35_RS08420	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LJA35_RS08430	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LJA35_RS08470	COG0395	ABC-type sugar transport system, permease component
LJA35_RS08475	COG1175	transmembrane transport
LJA35_RS08485	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LJA35_RS08490	COG1349	DNA-binding transcription factor activity
LJA35_RS08495	COG0785	Cytochrome C biogenesis protein
LJA35_RS08500	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LJA35_RS08500	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LJA35_RS08565	COG1024	Enoyl-CoA hydratase
LJA35_RS08575	COG0531	amino acid
LJA35_RS08580	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LJA35_RS08585	COG2235	arginine
LJA35_RS08590	COG0475	glutathione-regulated potassium exporter activity
LJA35_RS08595	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LJA35_RS08625	COG1799	cell septum assembly
LJA35_RS08630	COG0247	lactate metabolic process
LJA35_RS08630	COG0277	FAD linked oxidase domain protein
LJA35_RS08645	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LJA35_RS08655	COG0310	cobalt ion transport
LJA35_RS08660	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
LJA35_RS08670	COG1122	ATPase activity
LJA35_RS08690	COG0477	Major facilitator Superfamily
LJA35_RS08705	COG2205	protein histidine kinase activity
LJA35_RS08710	COG0745	RESPONSE REGULATOR receiver
LJA35_RS08720	COG2409	Drug exporters of the RND superfamily
LJA35_RS08730	COG2814	Major facilitator Superfamily
LJA35_RS08750	COG1309	transcriptional regulator
LJA35_RS08755	COG0318	PFAM AMP-dependent synthetase and ligase
LJA35_RS08765	COG0456	acetyltransferase
LJA35_RS08785	COG3693	PFAM glycoside hydrolase, family 10
LJA35_RS08840	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LJA35_RS08845	COG0531	amino acid
LJA35_RS08870	COG0500	methyltransferase
LJA35_RS08880	COG1088	dTDP-glucose 4,6-dehydratase activity
LJA35_RS08890	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LJA35_RS08895	COG0156	8-amino-7-oxononanoate synthase activity
LJA35_RS08900	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LJA35_RS08905	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LJA35_RS08910	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LJA35_RS08915	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LJA35_RS08920	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LJA35_RS08950	COG1960	acyl-CoA dehydrogenase activity
LJA35_RS08955	COG3321	synthase
LJA35_RS08960	COG3629	intracellular signal transduction
LJA35_RS08965	COG0569	domain protein
LJA35_RS08995	COG1136	(ABC) transporter
LJA35_RS08995	COG4591	ABC-type transport system involved in lipoprotein release permease component
LJA35_RS09005	COG0756	dUTP diphosphatase activity
LJA35_RS09030	COG2205	protein histidine kinase activity
LJA35_RS09035	COG0745	RESPONSE REGULATOR receiver
LJA35_RS09050	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LJA35_RS09090	COG1435	thymidine kinase activity
LJA35_RS09110	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LJA35_RS09115	COG1802	Transcriptional regulator
LJA35_RS09130	COG0612	Peptidase, M16
LJA35_RS09135	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LJA35_RS09155	COG0372	Belongs to the citrate synthase family
LJA35_RS09170	COG3290	protein histidine kinase activity
LJA35_RS09175	COG4565	transcriptional regulatory protein
LJA35_RS09180	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LJA35_RS09190	COG0187	DNA topoisomerase II activity
LJA35_RS09205	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LJA35_RS09210	COG2186	Transcriptional regulator
LJA35_RS09245	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LJA35_RS09265	COG0588	phosphoglycerate mutase activity
LJA35_RS09280	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LJA35_RS09285	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LJA35_RS09290	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LJA35_RS09325	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LJA35_RS09335	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LJA35_RS09340	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LJA35_RS09350	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LJA35_RS09370	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LJA35_RS09375	COG5297	Belongs to the glycosyl hydrolase family 6
LJA35_RS09375	COG4733	cellulase activity
LJA35_RS09380	COG2197	response regulator
LJA35_RS09385	COG3851	Histidine kinase
LJA35_RS09410	COG2205	protein histidine kinase activity
LJA35_RS09415	COG0745	RESPONSE REGULATOR receiver
LJA35_RS09420	COG1126	abc transporter atp-binding protein
LJA35_RS09425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LJA35_RS09430	COG0765	amino acid transport
LJA35_RS09435	COG0765	amino acid transport
LJA35_RS09450	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LJA35_RS09460	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LJA35_RS09470	COG0628	permease
LJA35_RS09495	COG1917	Cupin 2, conserved barrel domain protein
LJA35_RS09495	COG2207	Transcriptional regulator
LJA35_RS09500	COG1201	RNA secondary structure unwinding
LJA35_RS09505	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LJA35_RS09525	COG0783	Belongs to the Dps family
LJA35_RS09530	COG1396	sequence-specific DNA binding
LJA35_RS09535	COG1058	Belongs to the CinA family
LJA35_RS09535	COG1546	Belongs to the CinA family
LJA35_RS09545	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LJA35_RS09555	COG1674	ftsk spoiiie
LJA35_RS09565	COG2205	protein histidine kinase activity
LJA35_RS09565	COG3437	response regulator, receiver
LJA35_RS09565	COG3850	Histidine kinase
LJA35_RS09565	COG4999	Histidine kinase
LJA35_RS09570	COG2770	Histidine kinase
LJA35_RS09570	COG2208	phosphoserine phosphatase activity
LJA35_RS09595	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LJA35_RS09600	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LJA35_RS09605	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
LJA35_RS09625	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LJA35_RS09630	COG0612	Peptidase, M16
LJA35_RS09635	COG1185	polyribonucleotide nucleotidyltransferase activity
LJA35_RS09640	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LJA35_RS09660	COG1674	ftsk spoiiie
LJA35_RS09675	COG1404	Belongs to the peptidase S8 family
LJA35_RS09720	COG3266	domain, Protein
LJA35_RS09735	COG0455	bacterial-type flagellum organization
LJA35_RS09740	COG0747	negative chemotaxis
LJA35_RS09745	COG0601	transmembrane transport
LJA35_RS09750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LJA35_RS09760	COG4608	Belongs to the ABC transporter superfamily
LJA35_RS09775	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LJA35_RS09780	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LJA35_RS09790	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LJA35_RS09805	COG0779	Required for maturation of 30S ribosomal subunits
LJA35_RS09825	COG0442	prolyl-tRNA aminoacylation
LJA35_RS09840	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LJA35_RS09845	COG0750	zinc metalloprotease
LJA35_RS09850	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
LJA35_RS09880	COG0395	ABC-type sugar transport system, permease component
LJA35_RS09885	COG4209	transmembrane transport
LJA35_RS09895	COG1472	Belongs to the glycosyl hydrolase 3 family
LJA35_RS09900	COG2197	response regulator
LJA35_RS09915	COG0438	transferase activity, transferring glycosyl groups
LJA35_RS09920	COG1012	belongs to the aldehyde dehydrogenase family
LJA35_RS09925	COG2508	Transcriptional regulator
LJA35_RS09960	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LJA35_RS09965	COG1177	transmembrane transport
LJA35_RS09970	COG1176	ABC-type spermidine putrescine transport system, permease component I
LJA35_RS09975	COG3842	ATPase activity
LJA35_RS10005	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LJA35_RS10030	COG1012	belongs to the aldehyde dehydrogenase family
LJA35_RS10040	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LJA35_RS10075	COG3842	ATPase activity
LJA35_RS10080	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LJA35_RS10090	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LJA35_RS10095	COG0575	Belongs to the CDS family
LJA35_RS10100	COG0233	cytoplasmic translational termination
LJA35_RS10105	COG0528	UMP kinase activity
LJA35_RS10110	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LJA35_RS10115	COG0052	Belongs to the universal ribosomal protein uS2 family
LJA35_RS10120	COG4942	peptidase
LJA35_RS10130	COG1191	sigma factor activity
LJA35_RS10145	COG0792	nuclease activity
LJA35_RS10165	COG0681	Belongs to the peptidase S26 family
LJA35_RS10180	COG0335	large ribosomal subunit rRNA binding
LJA35_RS10185	COG0336	Belongs to the RNA methyltransferase TrmD family
LJA35_RS10190	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LJA35_RS10195	COG1837	Belongs to the UPF0109 family
LJA35_RS10200	COG0228	four-way junction DNA binding
LJA35_RS10225	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
LJA35_RS10260	COG0477	Major facilitator Superfamily
LJA35_RS10275	COG1254	Belongs to the acylphosphatase family
LJA35_RS10320	COG1733	regulation of RNA biosynthetic process
LJA35_RS10325	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LJA35_RS10330	COG0571	ribonuclease III activity
LJA35_RS10335	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LJA35_RS10350	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LJA35_RS10355	COG0742	ribosomal rna small subunit methyltransferase
LJA35_RS10370	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LJA35_RS10385	COG0351	phosphomethylpyrimidine kinase
LJA35_RS10400	COG1181	Belongs to the D-alanine--D-alanine ligase family
LJA35_RS10405	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LJA35_RS10415	COG1920	GTP binding
LJA35_RS10425	COG0776	regulation of translation
LJA35_RS10435	COG0066	3-isopropylmalate dehydratase activity
LJA35_RS10440	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LJA35_RS10445	COG1414	Transcriptional regulator
LJA35_RS10495	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LJA35_RS10500	COG0179	Fumarylacetoacetate (FAA) hydrolase
LJA35_RS10510	COG5002	protein histidine kinase activity
LJA35_RS10515	COG2018	Roadblock/LC7 domain
LJA35_RS10535	COG2018	Roadblock/LC7 domain
LJA35_RS10555	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LJA35_RS10560	COG5492	domain, Protein
LJA35_RS10565	COG2353	YceI-like domain
LJA35_RS10570	COG1335	isochorismatase
LJA35_RS10590	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LJA35_RS10600	COG2957	Belongs to the agmatine deiminase family
LJA35_RS10605	COG0804	urea catabolic process
LJA35_RS10610	COG0831	urea catabolic process
LJA35_RS10610	COG0832	Belongs to the urease beta subunit family
LJA35_RS10620	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LJA35_RS10625	COG0473	3-isopropylmalate dehydrogenase activity
LJA35_RS10630	COG1012	belongs to the aldehyde dehydrogenase family
LJA35_RS10635	COG0506	proline dehydrogenase activity
LJA35_RS10650	COG0477	Major facilitator Superfamily
LJA35_RS10655	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LJA35_RS10660	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LJA35_RS10665	COG0440	acetolactate synthase activity
LJA35_RS10675	COG5001	Diguanylate cyclase
LJA35_RS10685	COG0667	Aldo Keto reductase
LJA35_RS10690	COG2133	pyrroloquinoline quinone binding
LJA35_RS10700	COG2197	response regulator
LJA35_RS10715	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LJA35_RS10720	COG2409	Drug exporters of the RND superfamily
LJA35_RS10725	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LJA35_RS10735	COG0154	amidase activity
LJA35_RS10740	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LJA35_RS10765	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LJA35_RS10775	COG4221	oxidoreductase activity
LJA35_RS10780	COG1611	Belongs to the LOG family
LJA35_RS10795	COG0482	sulfurtransferase activity
LJA35_RS10820	COG1309	transcriptional regulator
LJA35_RS10830	COG0789	Transcriptional regulator
LJA35_RS10840	COG2860	membrane
LJA35_RS10845	COG4608	Belongs to the ABC transporter superfamily
LJA35_RS10850	COG0444	Belongs to the ABC transporter superfamily
LJA35_RS10865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LJA35_RS10885	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LJA35_RS10890	COG0509	glycine decarboxylation via glycine cleavage system
LJA35_RS10895	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LJA35_RS10900	COG1760	l-serine dehydratase
LJA35_RS10905	COG0492	ferredoxin-NADP+ reductase activity
LJA35_RS10910	COG0277	FAD linked oxidase domain protein
LJA35_RS10915	COG1045	serine acetyltransferase
LJA35_RS10935	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LJA35_RS10940	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LJA35_RS10950	COG0151	Belongs to the GarS family
LJA35_RS10955	COG0431	NADPH-dependent FMN reductase
LJA35_RS10970	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LJA35_RS10985	COG1063	alcohol dehydrogenase
LJA35_RS11000	COG2223	nitrite transmembrane transporter activity
LJA35_RS11005	COG0243	molybdopterin cofactor binding
LJA35_RS11015	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LJA35_RS11015	COG2146	nitrite reductase [NAD(P)H] activity
LJA35_RS11030	COG0655	NAD(P)H dehydrogenase (quinone) activity
LJA35_RS11040	COG0655	NAD(P)H dehydrogenase (quinone) activity
LJA35_RS11055	COG1959	2 iron, 2 sulfur cluster binding
LJA35_RS11085	COG1028	Short-chain dehydrogenase reductase Sdr
LJA35_RS11120	COG3321	synthase
LJA35_RS11120	COG0318	PFAM AMP-dependent synthetase and ligase
LJA35_RS11120	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LJA35_RS11120	COG0300	oxidoreductase activity
LJA35_RS11120	COG1028	Short-chain dehydrogenase reductase Sdr
LJA35_RS11125	COG2207	Transcriptional regulator
LJA35_RS11130	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LJA35_RS11145	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LJA35_RS11160	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
LJA35_RS11180	COG0583	DNA-binding transcription factor activity
LJA35_RS11195	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LJA35_RS11200	COG1309	transcriptional regulator
LJA35_RS11220	COG3467	pyridoxamine 5'-phosphate
LJA35_RS11230	COG1028	Short-chain dehydrogenase reductase Sdr
LJA35_RS11230	COG0300	oxidoreductase activity
LJA35_RS11230	COG0318	PFAM AMP-dependent synthetase and ligase
LJA35_RS11230	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LJA35_RS11230	COG3321	synthase
LJA35_RS11270	COG0789	Transcriptional regulator
LJA35_RS11310	COG2197	response regulator
LJA35_RS11315	COG4585	Histidine kinase
LJA35_RS11325	COG1131	(ABC) transporter
LJA35_RS11330	COG1132	(ABC) transporter
LJA35_RS11335	COG1132	(ABC) transporter
LJA35_RS11340	COG1132	(ABC) transporter
LJA35_RS11345	COG1132	(ABC) transporter
LJA35_RS11365	COG0058	SHG alpha-glucan phosphorylase activity
LJA35_RS11370	COG0366	Alpha amylase catalytic
LJA35_RS11375	COG0366	Alpha amylase catalytic
LJA35_RS11380	COG3281	Trehalose synthase
LJA35_RS11385	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LJA35_RS11395	COG3118	belongs to the thioredoxin family
LJA35_RS11395	COG0492	ferredoxin-NADP+ reductase activity
LJA35_RS11405	COG1301	dicarboxylic acid transport
LJA35_RS11410	COG3290	protein histidine kinase activity
LJA35_RS11415	COG4565	transcriptional regulatory protein
LJA35_RS11485	COG1653	transport
LJA35_RS11495	COG0395	ABC-type sugar transport system, permease component
LJA35_RS11505	COG0205	6-phosphofructokinase activity
LJA35_RS11510	COG0857	belongs to the CobB CobQ family
LJA35_RS11510	COG0280	phosphate acetyltransferase
LJA35_RS11515	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LJA35_RS11550	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LJA35_RS11550	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LJA35_RS11595	COG2205	protein histidine kinase activity
LJA35_RS11600	COG0745	RESPONSE REGULATOR receiver
LJA35_RS11620	COG0183	Belongs to the thiolase family
LJA35_RS11640	COG1131	(ABC) transporter
LJA35_RS11675	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
LJA35_RS11690	COG1250	3-hydroxyacyl-CoA dehydrogenase
LJA35_RS11730	COG2197	response regulator
LJA35_RS11745	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LJA35_RS11750	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LJA35_RS11755	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LJA35_RS11760	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LJA35_RS11765	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LJA35_RS11770	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LJA35_RS11775	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LJA35_RS11790	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LJA35_RS11795	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LJA35_RS11800	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LJA35_RS11810	COG2890	protein-(glutamine-N5) methyltransferase activity
LJA35_RS11815	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LJA35_RS11820	COG0254	rRNA binding
LJA35_RS11825	COG1316	TRANSCRIPTIONal
LJA35_RS11840	COG0083	homoserine kinase activity
LJA35_RS11845	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LJA35_RS11850	COG0460	homoserine dehydrogenase
LJA35_RS11855	COG0019	diaminopimelate decarboxylase activity
LJA35_RS11860	COG0018	arginyl-trna synthetase
LJA35_RS11860	COG0018	arginyl-trna synthetase
LJA35_RS11865	COG0745	RESPONSE REGULATOR receiver
LJA35_RS11880	COG1733	regulation of RNA biosynthetic process
LJA35_RS11890	COG1683	Conserved Protein
LJA35_RS11910	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LJA35_RS11915	COG2329	Antibiotic biosynthesis monooxygenase
LJA35_RS11920	COG0662	Cupin 2, conserved barrel domain protein
LJA35_RS11925	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LJA35_RS11930	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LJA35_RS11935	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LJA35_RS11940	COG2867	negative regulation of translational initiation
LJA35_RS11955	COG3467	pyridoxamine 5'-phosphate
LJA35_RS11970	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
LJA35_RS11975	COG3285	dna ligase
LJA35_RS11975	COG1793	dna ligase
LJA35_RS11995	COG2205	protein histidine kinase activity
LJA35_RS12035	COG3883	PFAM NLP P60 protein
LJA35_RS12035	COG0791	NLP P60 protein
LJA35_RS12080	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LJA35_RS12090	COG0745	RESPONSE REGULATOR receiver
LJA35_RS12095	COG2205	protein histidine kinase activity
LJA35_RS12100	COG0567	Dehydrogenase, E1 component
LJA35_RS12100	COG0508	dehydrogenase complex catalyzes the overall conversion of
LJA35_RS12165	COG0542	response to heat
LJA35_RS12175	COG0604	alcohol dehydrogenase
LJA35_RS12180	COG0281	malic enzyme
LJA35_RS12195	COG1126	abc transporter atp-binding protein
LJA35_RS12200	COG4106	trans-aconitate 2-methyltransferase activity
LJA35_RS12235	COG0142	geranyltranstransferase activity
LJA35_RS12240	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LJA35_RS12280	COG1597	lipid kinase activity
LJA35_RS12300	COG0363	glucosamine-6-phosphate deaminase activity
LJA35_RS12305	COG1472	Belongs to the glycosyl hydrolase 3 family
LJA35_RS12310	COG0395	ABC-type sugar transport system, permease component
LJA35_RS12315	COG1175	transmembrane transport
LJA35_RS12320	COG2182	Extracellular solute-binding protein
LJA35_RS12325	COG2188	Transcriptional regulator
LJA35_RS12365	COG2124	cytochrome p450
LJA35_RS12375	COG0242	peptide deformylase activity
LJA35_RS12395	COG5662	AntiSigma factor
LJA35_RS12400	COG1595	DNA-templated transcription, initiation
LJA35_RS12410	COG2135	peptidase activity
LJA35_RS12420	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LJA35_RS12430	COG2076	Multidrug Resistance protein
LJA35_RS12440	COG0483	inositol monophosphate 1-phosphatase activity
LJA35_RS12450	COG0753	catalase activity
LJA35_RS12475	COG1615	UPF0182 protein
LJA35_RS12485	COG3480	Lon protease (S16) C-terminal proteolytic domain
LJA35_RS12540	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LJA35_RS12570	COG2816	NAD+ diphosphatase activity
LJA35_RS12580	COG0210	DNA helicase
LJA35_RS12605	COG0596	Alpha beta hydrolase
LJA35_RS12640	COG0596	Alpha beta hydrolase
LJA35_RS12640	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LJA35_RS12670	COG0513	Belongs to the DEAD box helicase family
LJA35_RS12680	COG1432	Conserved Protein
LJA35_RS12690	COG2095	MarC family integral membrane protein
LJA35_RS12695	COG0613	PHP domain protein
LJA35_RS12705	COG2814	Major facilitator Superfamily
LJA35_RS12715	COG0598	Magnesium transport protein CorA
LJA35_RS12750	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LJA35_RS12755	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LJA35_RS12765	COG1595	DNA-templated transcription, initiation
LJA35_RS12780	COG1024	Enoyl-CoA hydratase
LJA35_RS12785	COG0519	Catalyzes the synthesis of GMP from XMP
LJA35_RS12795	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LJA35_RS12805	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LJA35_RS12850	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LJA35_RS12875	COG4608	Belongs to the ABC transporter superfamily
LJA35_RS12880	COG0444	Belongs to the ABC transporter superfamily
LJA35_RS12885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LJA35_RS12890	COG0601	transmembrane transport
LJA35_RS12900	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LJA35_RS12905	COG0747	negative chemotaxis
LJA35_RS12915	COG0444	Belongs to the ABC transporter superfamily
LJA35_RS12930	COG4608	Belongs to the ABC transporter superfamily
LJA35_RS12935	COG0444	Belongs to the ABC transporter superfamily
LJA35_RS12940	COG0601	transmembrane transport
LJA35_RS12945	COG0747	negative chemotaxis
LJA35_RS12950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LJA35_RS12955	COG1217	gtp-binding protein TYPA
LJA35_RS12975	COG1053	succinate dehydrogenase
LJA35_RS12980	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LJA35_RS13025	COG0300	oxidoreductase activity
LJA35_RS13030	COG0583	DNA-binding transcription factor activity
LJA35_RS13055	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LJA35_RS13080	COG2264	protein methyltransferase activity
LJA35_RS13110	COG0012	GTP binding
LJA35_RS13125	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LJA35_RS13135	COG1570	exodeoxyribonuclease VII activity
LJA35_RS13140	COG1722	exodeoxyribonuclease VII activity
LJA35_RS13150	COG0778	Nitroreductase
LJA35_RS13175	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
LJA35_RS13175	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
LJA35_RS13185	COG0114	fumarate hydratase activity
LJA35_RS13200	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LJA35_RS13220	COG1136	(ABC) transporter
LJA35_RS13235	COG0450	alkyl hydroperoxide reductase
LJA35_RS13240	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LJA35_RS13250	COG0741	lytic transglycosylase activity
LJA35_RS13255	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LJA35_RS13260	COG2226	methyltransferase
LJA35_RS13330	COG2894	cell division
LJA35_RS13375	COG2610	gluconate transmembrane transporter activity
LJA35_RS13380	COG0251	oxidation-reduction process
LJA35_RS13385	COG1414	Transcriptional regulator
LJA35_RS13400	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
LJA35_RS13405	COG0436	Aminotransferase
LJA35_RS13415	COG2267	carboxylic ester hydrolase activity
LJA35_RS13420	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
LJA35_RS13440	COG1331	Highly conserved protein containing a thioredoxin domain
LJA35_RS13445	COG0590	tRNA wobble adenosine to inosine editing
LJA35_RS13455	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LJA35_RS13465	COG2255	four-way junction helicase activity
LJA35_RS13475	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LJA35_RS13485	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LJA35_RS13500	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LJA35_RS13530	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LJA35_RS13555	COG0667	Aldo Keto reductase
LJA35_RS13570	COG1140	nitrate reductase beta subunit
LJA35_RS13580	COG1090	epimerase
LJA35_RS13585	COG1064	alcohol dehydrogenase
LJA35_RS13625	COG2986	histidine ammonia-lyase
LJA35_RS13635	COG1024	Enoyl-CoA hydratase
LJA35_RS13645	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
LJA35_RS13655	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LJA35_RS13665	COG0424	maF-like protein
LJA35_RS13675	COG4770	biotin carboxylase activity
LJA35_RS13700	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LJA35_RS13715	COG1012	belongs to the aldehyde dehydrogenase family
LJA35_RS13720	COG1012	belongs to the aldehyde dehydrogenase family
LJA35_RS13725	COG0515	serine threonine protein kinase
LJA35_RS13750	COG1595	DNA-templated transcription, initiation
LJA35_RS13755	COG0745	RESPONSE REGULATOR receiver
LJA35_RS13760	COG2205	protein histidine kinase activity
LJA35_RS13785	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LJA35_RS13790	COG1959	2 iron, 2 sulfur cluster binding
LJA35_RS13795	COG1028	Short-chain dehydrogenase reductase Sdr
LJA35_RS13805	COG0583	DNA-binding transcription factor activity
LJA35_RS13810	COG2814	Major facilitator Superfamily
LJA35_RS13845	COG1079	Belongs to the binding-protein-dependent transport system permease family
LJA35_RS13850	COG4603	Belongs to the binding-protein-dependent transport system permease family
LJA35_RS13855	COG3845	ABC transporter
LJA35_RS13860	COG1744	ABC transporter substrate-binding protein PnrA-like
LJA35_RS13865	COG1744	ABC transporter substrate-binding protein PnrA-like
LJA35_RS13870	COG1473	amidohydrolase
LJA35_RS13870	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
LJA35_RS13880	COG2089	acid synthase
LJA35_RS13895	COG1216	Glycosyl transferase, family 2
LJA35_RS13910	COG0463	Glycosyl transferase, family 2
LJA35_RS13940	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LJA35_RS13940	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LJA35_RS13955	COG1595	DNA-templated transcription, initiation
LJA35_RS13965	COG1595	DNA-templated transcription, initiation
LJA35_RS13995	COG2009	succinate dehydrogenase
LJA35_RS14005	COG1053	succinate dehydrogenase
LJA35_RS14030	COG1309	transcriptional regulator
LJA35_RS14035	COG1408	metallophosphoesterase
LJA35_RS14045	COG1686	Belongs to the peptidase S11 family
LJA35_RS14085	COG0180	Tryptophanyl-tRNA synthetase
LJA35_RS14095	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LJA35_RS14100	COG0754	glutathionylspermidine amidase activity
LJA35_RS14110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LJA35_RS14115	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LJA35_RS14120	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LJA35_RS14125	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LJA35_RS14140	COG4175	Glycine betaine
LJA35_RS14140	COG0517	IMP dehydrogenase activity
LJA35_RS14150	COG1012	belongs to the aldehyde dehydrogenase family
LJA35_RS14155	COG0039	L-malate dehydrogenase activity
LJA35_RS14170	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LJA35_RS14200	COG0515	serine threonine protein kinase
LJA35_RS14200	COG2815	serine threonine protein kinase
LJA35_RS14205	COG0138	bifunctional purine biosynthesis protein purh
LJA35_RS14235	COG0045	succinate-CoA ligase (ADP-forming) activity
LJA35_RS14245	COG3552	Protein containing von Willebrand factor type A (VWA) domain
LJA35_RS14250	COG2425	protein containing a von Willebrand factor type A (vWA) domain
LJA35_RS14255	COG0714	Associated with various cellular activities
LJA35_RS14270	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LJA35_RS14270	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LJA35_RS14280	COG0739	heme binding
LJA35_RS14310	COG2197	response regulator
LJA35_RS14345	COG0519	Catalyzes the synthesis of GMP from XMP
LJA35_RS14345	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LJA35_RS14365	COG1012	belongs to the aldehyde dehydrogenase family
LJA35_RS14370	COG0515	serine threonine protein kinase
LJA35_RS14380	COG0515	serine threonine protein kinase
LJA35_RS14385	COG2815	serine threonine protein kinase
LJA35_RS14385	COG0515	serine threonine protein kinase
LJA35_RS14395	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LJA35_RS14405	COG0516	GMP reductase activity
LJA35_RS14415	COG1595	DNA-templated transcription, initiation
LJA35_RS14430	COG0583	DNA-binding transcription factor activity
LJA35_RS14440	COG4221	oxidoreductase activity
LJA35_RS14460	COG1280	lysine exporter protein (LysE YggA)
LJA35_RS14495	COG0459	protein refolding
LJA35_RS14500	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LJA35_RS14505	COG0726	polysaccharide deacetylase
LJA35_RS14510	COG0726	polysaccharide deacetylase
LJA35_RS14520	COG4941	Belongs to the sigma-70 factor family
LJA35_RS14530	COG1316	TRANSCRIPTIONal
LJA35_RS14545	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LJA35_RS14545	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LJA35_RS14565	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LJA35_RS14575	COG0456	acetyltransferase
LJA35_RS14575	COG1214	PFAM Peptidase M22, glycoprotease
LJA35_RS14590	COG0802	atpase or kinase
LJA35_RS14600	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LJA35_RS14605	COG0736	holo-[acyl-carrier-protein] synthase activity
LJA35_RS14625	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LJA35_RS14635	COG1072	(Pantothenic acid kinase))
LJA35_RS14650	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LJA35_RS14655	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LJA35_RS14660	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LJA35_RS14675	COG0101	tRNA pseudouridine synthase activity
LJA35_RS14680	COG0203	ribosomal protein L17
LJA35_RS14690	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LJA35_RS14695	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LJA35_RS14700	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LJA35_RS14705	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LJA35_RS14715	COG0563	adenylate kinase activity
LJA35_RS14720	COG0201	protein transport
LJA35_RS14725	COG0200	Binds to the 23S rRNA
LJA35_RS14730	COG1841	ribosomal large subunit assembly
LJA35_RS14735	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LJA35_RS14740	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LJA35_RS14745	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LJA35_RS14750	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LJA35_RS14755	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LJA35_RS14760	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LJA35_RS14765	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LJA35_RS14770	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LJA35_RS14775	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LJA35_RS14780	COG0255	Belongs to the universal ribosomal protein uL29 family
LJA35_RS14785	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LJA35_RS14790	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LJA35_RS14795	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LJA35_RS14800	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LJA35_RS14805	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LJA35_RS14810	COG0089	rRNA binding
LJA35_RS14815	COG0088	Forms part of the polypeptide exit tunnel
LJA35_RS14820	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LJA35_RS14825	COG0051	transcription antitermination factor activity, RNA binding
LJA35_RS14870	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LJA35_RS14880	COG1028	Short-chain dehydrogenase reductase Sdr
LJA35_RS14940	COG0583	DNA-binding transcription factor activity
LJA35_RS14970	COG2197	response regulator
LJA35_RS14980	COG1136	(ABC) transporter
LJA35_RS14995	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LJA35_RS15000	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LJA35_RS15005	COG0049	tRNA binding
LJA35_RS15010	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LJA35_RS15130	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LJA35_RS15135	COG0085	RNA polymerase activity
LJA35_RS15140	COG0222	ribosome binding
LJA35_RS15145	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LJA35_RS15160	COG0081	regulation of translation
LJA35_RS15165	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LJA35_RS15170	COG0250	Participates in transcription elongation, termination and antitermination
LJA35_RS15175	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LJA35_RS15185	COG0436	Aminotransferase
LJA35_RS15190	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LJA35_RS15205	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LJA35_RS15215	COG0477	Major facilitator Superfamily
LJA35_RS15240	COG2030	dehydratase
LJA35_RS15245	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LJA35_RS15260	COG0402	S-adenosylhomocysteine deaminase activity
LJA35_RS15265	COG0702	epimerase
LJA35_RS15285	COG1666	GTP binding
LJA35_RS15290	COG2261	transglycosylase associated protein
LJA35_RS15300	COG3304	Inner membrane component domain
LJA35_RS15305	COG0501	Belongs to the peptidase M48B family
LJA35_RS15310	COG1007	ATP synthesis coupled electron transport
LJA35_RS15320	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LJA35_RS15325	COG0713	ATP synthesis coupled electron transport
LJA35_RS15335	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LJA35_RS15340	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LJA35_RS15345	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LJA35_RS15350	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LJA35_RS15355	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LJA35_RS15375	COG0674	pyruvate-flavodoxin oxidoreductase activity
LJA35_RS15375	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
LJA35_RS15380	COG1013	pyruvate-flavodoxin oxidoreductase activity
LJA35_RS15385	COG0702	epimerase
LJA35_RS15430	COG1196	nuclear chromosome segregation
LJA35_RS15430	COG0739	heme binding
LJA35_RS15430	COG0741	lytic transglycosylase activity
LJA35_RS15505	COG1131	(ABC) transporter
LJA35_RS15515	COG0142	geranyltranstransferase activity
LJA35_RS15525	COG0561	phosphatase activity
LJA35_RS15540	COG0514	ATP-dependent DNA helicase (RecQ)
LJA35_RS15550	COG1007	ATP synthesis coupled electron transport
LJA35_RS15560	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LJA35_RS15565	COG0713	ATP synthesis coupled electron transport
LJA35_RS15570	COG0839	Belongs to the complex I subunit 6 family
LJA35_RS15575	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LJA35_RS15580	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LJA35_RS15585	COG1034	ATP synthesis coupled electron transport
LJA35_RS15590	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LJA35_RS15600	COG0649	NAD binding
LJA35_RS15605	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LJA35_RS15610	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LJA35_RS15625	COG0242	peptide deformylase activity
LJA35_RS15645	COG2226	methyltransferase
LJA35_RS15675	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
LJA35_RS15690	COG0515	serine threonine protein kinase
LJA35_RS15690	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LJA35_RS15695	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LJA35_RS15695	COG0515	serine threonine protein kinase
LJA35_RS15700	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
LJA35_RS15705	COG1278	Cold shock
LJA35_RS15710	COG2226	methyltransferase
LJA35_RS15735	COG1309	transcriptional regulator
LJA35_RS15740	COG1301	dicarboxylic acid transport
LJA35_RS15755	COG1573	uracil-dna glycosylase
LJA35_RS15760	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
LJA35_RS15770	COG0163	prenyltransferase activity
LJA35_RS15775	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LJA35_RS15780	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
LJA35_RS15830	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LJA35_RS15835	COG1333	cytochrome c biogenesis protein
LJA35_RS15840	COG0785	Cytochrome C biogenesis protein
LJA35_RS15845	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LJA35_RS15855	COG0406	alpha-ribazole phosphatase activity
LJA35_RS15860	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LJA35_RS15880	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LJA35_RS15910	COG0640	Transcriptional regulator
LJA35_RS15915	COG0798	PFAM Bile acid sodium symporter
LJA35_RS15925	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LJA35_RS15965	COG1007	ATP synthesis coupled electron transport
LJA35_RS15980	COG0713	ATP synthesis coupled electron transport
LJA35_RS15990	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LJA35_RS16000	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LJA35_RS16025	COG0569	domain protein
LJA35_RS16025	COG0475	glutathione-regulated potassium exporter activity
LJA35_RS16045	COG1366	Belongs to the anti-sigma-factor antagonist family
LJA35_RS16045	COG2208	phosphoserine phosphatase activity
LJA35_RS16045	COG2172	sigma factor antagonist activity
LJA35_RS16065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LJA35_RS16070	COG1742	UPF0060 membrane protein
LJA35_RS16085	COG1690	Belongs to the RtcB family
LJA35_RS16105	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
LJA35_RS16110	COG0018	arginyl-trna synthetase
LJA35_RS16115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LJA35_RS16135	COG0113	porphobilinogen synthase activity
LJA35_RS16150	COG3321	synthase
LJA35_RS16150	COG0604	alcohol dehydrogenase
LJA35_RS16195	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LJA35_RS16215	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
LJA35_RS16230	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LJA35_RS16230	COG1648	precorrin-2 dehydrogenase activity
LJA35_RS16235	COG0181	hydroxymethylbilane synthase activity
LJA35_RS16240	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LJA35_RS16245	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LJA35_RS16295	COG0123	including yeast histone deacetylase and acetoin utilization protein
LJA35_RS16315	COG0180	Tryptophanyl-tRNA synthetase
LJA35_RS16330	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LJA35_RS16340	COG0842	Transport permease protein
LJA35_RS16340	COG1129	ABC transporter
LJA35_RS16365	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LJA35_RS16365	COG0515	serine threonine protein kinase
LJA35_RS16370	COG0129	dihydroxy-acid dehydratase activity
LJA35_RS16380	COG1082	Xylose isomerase domain protein TIM barrel
LJA35_RS16385	COG0248	Ppx GppA phosphatase
LJA35_RS16405	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
LJA35_RS16415	COG1194	a g-specific adenine glycosylase
LJA35_RS16420	COG1595	DNA-templated transcription, initiation
LJA35_RS16430	COG0745	RESPONSE REGULATOR receiver
LJA35_RS16435	COG2205	protein histidine kinase activity
LJA35_RS16445	COG0346	lactoylglutathione lyase activity
LJA35_RS16480	COG0739	heme binding
LJA35_RS16520	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LJA35_RS16535	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LJA35_RS16545	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LJA35_RS16550	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LJA35_RS16575	COG1660	Displays ATPase and GTPase activities
LJA35_RS16595	COG0649	NAD binding
LJA35_RS16635	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LJA35_RS16650	COG0302	gtp cyclohydrolase
LJA35_RS16665	COG0037	tRNA processing
LJA35_RS16675	COG2027	D-alanyl-D-alanine carboxypeptidase
LJA35_RS16680	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LJA35_RS16690	COG0586	Pfam SNARE associated Golgi protein
LJA35_RS16695	COG0789	Transcriptional regulator
LJA35_RS16710	COG0076	glutamate decarboxylase activity
LJA35_RS16730	COG1012	belongs to the aldehyde dehydrogenase family
LJA35_RS16750	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LJA35_RS16760	COG0254	rRNA binding
LJA35_RS16765	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LJA35_RS16770	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LJA35_RS16775	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LJA35_RS16795	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LJA35_RS16795	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LJA35_RS16810	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LJA35_RS16820	COG1846	Transcriptional regulator
LJA35_RS16840	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LJA35_RS16845	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LJA35_RS16850	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LJA35_RS16850	COG1754	DNA topoisomerase type I activity
LJA35_RS16870	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
LJA35_RS16875	COG2172	sigma factor antagonist activity
LJA35_RS16880	COG1366	Belongs to the anti-sigma-factor antagonist family
LJA35_RS16885	COG1205	dead DEAH box helicase
LJA35_RS16885	COG1111	helicase
LJA35_RS16945	COG0659	secondary active sulfate transmembrane transporter activity
LJA35_RS16950	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LJA35_RS16955	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LJA35_RS16965	COG0596	Alpha beta hydrolase
LJA35_RS16980	COG0494	nUDIX hydrolase
LJA35_RS16995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LJA35_RS17005	COG0596	Alpha beta hydrolase
LJA35_RS17025	COG0003	Pfam Anion-transporting ATPase
LJA35_RS17035	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LJA35_RS17055	COG1408	metallophosphoesterase
LJA35_RS17075	COG1309	transcriptional regulator
LJA35_RS17095	COG2205	protein histidine kinase activity
LJA35_RS17100	COG0745	RESPONSE REGULATOR receiver
LJA35_RS17110	COG1234	tRNA 3'-trailer cleavage
LJA35_RS17120	COG0475	glutathione-regulated potassium exporter activity
LJA35_RS17170	COG1595	DNA-templated transcription, initiation
LJA35_RS17200	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LJA35_RS17205	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LJA35_RS17220	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LJA35_RS17225	COG1802	Transcriptional regulator
LJA35_RS17240	COG1595	DNA-templated transcription, initiation
LJA35_RS17255	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LJA35_RS17270	COG1131	(ABC) transporter
LJA35_RS17275	COG3559	Exporter of polyketide antibiotics
LJA35_RS17300	COG2197	response regulator
LJA35_RS17310	COG2197	response regulator
LJA35_RS17315	COG4585	Histidine kinase
LJA35_RS17335	COG3844	kynureninase activity
LJA35_RS17350	COG0477	Major facilitator Superfamily
LJA35_RS17355	COG0191	fructose-bisphosphate aldolase activity
LJA35_RS17360	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LJA35_RS17375	COG2197	response regulator
LJA35_RS17380	COG4585	Histidine kinase
LJA35_RS17385	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LJA35_RS17410	COG0542	response to heat
LJA35_RS17440	COG4213	ABC transporter substrate-binding protein
LJA35_RS17445	COG0789	Transcriptional regulator
LJA35_RS17450	COG0484	heat shock protein binding
LJA35_RS17455	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LJA35_RS17460	COG0443	Heat shock 70 kDa protein
LJA35_RS17465	COG2181	nitrate reductase activity
LJA35_RS17465	COG0247	lactate metabolic process
LJA35_RS17490	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
LJA35_RS17495	COG0717	Belongs to the dCTP deaminase family
LJA35_RS17540	COG1252	NADH dehydrogenase
LJA35_RS17545	COG1595	DNA-templated transcription, initiation
LJA35_RS17550	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
LJA35_RS17555	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
LJA35_RS17560	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
LJA35_RS17630	COG1278	Cold shock
LJA35_RS17635	COG0513	Belongs to the DEAD box helicase family
LJA35_RS17670	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LJA35_RS17675	COG5002	protein histidine kinase activity
LJA35_RS17680	COG0745	RESPONSE REGULATOR receiver
LJA35_RS17715	COG4585	Histidine kinase
LJA35_RS17725	COG1136	(ABC) transporter
LJA35_RS17725	COG0577	efflux transmembrane transporter activity
LJA35_RS17740	COG1136	(ABC) transporter
LJA35_RS17740	COG0577	efflux transmembrane transporter activity
LJA35_RS17745	COG2197	response regulator
LJA35_RS17750	COG4585	Histidine kinase
LJA35_RS17800	COG0583	DNA-binding transcription factor activity
LJA35_RS17825	COG1957	nucleoside hydrolase
LJA35_RS17830	COG0366	Alpha amylase catalytic
LJA35_RS17885	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LJA35_RS17895	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LJA35_RS17910	COG1741	Belongs to the pirin family
LJA35_RS17920	COG1960	acyl-CoA dehydrogenase activity
LJA35_RS17925	COG1362	aminopeptidase activity
LJA35_RS17960	COG2186	Transcriptional regulator
LJA35_RS17985	COG0508	dehydrogenase complex catalyzes the overall conversion of
LJA35_RS17990	COG0022	dehydrogenase e1 component
LJA35_RS18010	COG0515	serine threonine protein kinase
LJA35_RS18015	COG0515	serine threonine protein kinase
LJA35_RS18030	COG0604	alcohol dehydrogenase
LJA35_RS18030	COG1028	Short-chain dehydrogenase reductase Sdr
LJA35_RS18030	COG3321	synthase
LJA35_RS18045	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LJA35_RS18075	COG1522	sequence-specific DNA binding
LJA35_RS18080	COG1309	transcriptional regulator
LJA35_RS18085	COG1250	3-hydroxyacyl-CoA dehydrogenase
LJA35_RS18135	COG1716	ATPase activity
LJA35_RS18140	COG1716	ATPase activity
LJA35_RS18155	COG0768	penicillin binding
LJA35_RS18160	COG0515	serine threonine protein kinase
LJA35_RS18165	COG3764	Sortase (surface protein transpeptidase)
LJA35_RS18170	COG3764	Sortase (surface protein transpeptidase)
LJA35_RS18195	COG0705	Rhomboid family
LJA35_RS18210	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LJA35_RS18225	COG0515	serine threonine protein kinase
LJA35_RS18270	COG2319	Wd-40 repeat
LJA35_RS18270	COG4249	Peptidase C14 caspase catalytic subunit p20
LJA35_RS18285	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LJA35_RS18290	COG0187	DNA topoisomerase II activity
LJA35_RS18295	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
LJA35_RS18300	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LJA35_RS18305	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
LJA35_RS18310	COG0592	DNA-directed DNA polymerase activity
LJA35_RS18315	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LJA35_RS18320	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LJA35_RS18325	COG0594	ribonuclease P activity
LJA35_RS18330	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
LJA35_RS18335	COG0706	membrane insertase activity
LJA35_RS18345	COG0357	Ribosomal RNA small subunit methyltransferase G
LJA35_RS18350	COG1192	Involved in chromosome partitioning
LJA35_RS18365	COG3118	belongs to the thioredoxin family
LJA35_RS18370	COG0492	ferredoxin-NADP+ reductase activity
LJA35_RS18380	COG1595	DNA-templated transcription, initiation
LJA35_RS18400	COG0617	tRNA 3'-terminal CCA addition
LJA35_RS18430	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LJA35_RS18455	COG0360	Binds together with S18 to 16S ribosomal RNA
LJA35_RS18460	COG0629	single-stranded DNA binding
LJA35_RS18465	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LJA35_RS18470	COG0359	binds to the 23S rRNA
LJA35_RS18480	COG0305	Participates in initiation and elongation during chromosome replication
LJA35_RS18500	COG2814	Major facilitator Superfamily
LJA35_RS18525	COG0626	cystathionine gamma-synthase activity
LJA35_RS18530	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LJA35_RS18535	COG1950	PFAM Membrane protein of
LJA35_RS18540	COG0662	Cupin 2, conserved barrel domain protein
LJA35_RS18565	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LJA35_RS18585	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LJA35_RS18590	COG1609	Transcriptional regulator
LJA35_RS18595	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LJA35_RS18605	COG1271	oxidase subunit
LJA35_RS18610	COG1294	oxidase, subunit
LJA35_RS18615	COG4988	ABC transporter
LJA35_RS18625	COG0739	heme binding
LJA35_RS18630	COG0561	phosphatase activity
LJA35_RS18645	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
LJA35_RS18655	COG1131	(ABC) transporter
LJA35_RS18675	COG0561	phosphatase activity
LJA35_RS18680	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LJA35_RS18685	COG0077	Prephenate dehydratase
LJA35_RS18690	COG2837	iron assimilation
LJA35_RS18705	COG1999	signal sequence binding
LJA35_RS18725	COG0006	proline dipeptidase activity
LJA35_RS18745	COG0653	protein targeting
LJA35_RS18760	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LJA35_RS18770	COG1309	transcriptional regulator
LJA35_RS18785	COG0789	Transcriptional regulator
LJA35_RS18800	COG1595	DNA-templated transcription, initiation
LJA35_RS18805	COG0318	PFAM AMP-dependent synthetase and ligase
LJA35_RS18810	COG2814	Major facilitator Superfamily
LJA35_RS18815	COG1309	transcriptional regulator
LJA35_RS18820	COG0784	Response regulator, receiver
LJA35_RS18845	COG0768	penicillin binding
LJA35_RS18850	COG1733	regulation of RNA biosynthetic process
LJA35_RS18865	COG0745	RESPONSE REGULATOR receiver
LJA35_RS18870	COG2205	protein histidine kinase activity
LJA35_RS18880	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LJA35_RS18885	COG0477	Major facilitator Superfamily
LJA35_RS18895	COG3467	pyridoxamine 5'-phosphate
LJA35_RS18920	COG0477	Major facilitator Superfamily
LJA35_RS18935	COG1191	sigma factor activity
LJA35_RS18940	COG1191	sigma factor activity
LJA35_RS18975	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LJA35_RS19060	COG1434	Gram-negative-bacterium-type cell wall biogenesis
LJA35_RS19065	COG2188	Transcriptional regulator
LJA35_RS19150	COG0151	Belongs to the GarS family
LJA35_RS19165	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LJA35_RS19175	COG2197	response regulator
LJA35_RS19210	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LJA35_RS19215	COG0047	phosphoribosylformylglycinamidine synthase activity
LJA35_RS19220	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LJA35_RS19255	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LJA35_RS19290	COG1643	Atp-dependent helicase
LJA35_RS19365	COG2860	membrane
LJA35_RS19370	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LJA35_RS19370	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LJA35_RS19400	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LJA35_RS19410	COG0579	oxidoreductase
LJA35_RS19445	COG1252	NADH dehydrogenase
LJA35_RS19460	COG1846	Transcriptional regulator
LJA35_RS19465	COG2197	response regulator
LJA35_RS19470	COG4585	Histidine kinase
LJA35_RS19530	COG0741	lytic transglycosylase activity
LJA35_RS19530	COG0739	heme binding
LJA35_RS19530	COG1196	nuclear chromosome segregation
LJA35_RS19535	COG0671	phosphoesterase, PA-phosphatase related
LJA35_RS19540	COG0277	FAD linked oxidase domain protein
LJA35_RS19555	COG1937	Protein conserved in bacteria
LJA35_RS19565	COG0306	phosphate transporter
LJA35_RS19570	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LJA35_RS19590	COG0494	nUDIX hydrolase
LJA35_RS19590	COG0406	alpha-ribazole phosphatase activity
LJA35_RS19600	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LJA35_RS19630	COG0456	acetyltransferase
LJA35_RS19635	COG0737	Belongs to the 5'-nucleotidase family
LJA35_RS19640	COG1733	regulation of RNA biosynthetic process
LJA35_RS19655	COG0745	RESPONSE REGULATOR receiver
LJA35_RS19660	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LJA35_RS19665	COG1609	Transcriptional regulator
LJA35_RS19670	COG0745	RESPONSE REGULATOR receiver
LJA35_RS19695	COG2897	thiosulfate sulfurtransferase activity
LJA35_RS19715	COG1028	Short-chain dehydrogenase reductase Sdr
LJA35_RS19750	COG3485	protocatechuate 3,4-dioxygenase
LJA35_RS19755	COG0735	belongs to the Fur family
LJA35_RS19760	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LJA35_RS19765	COG1490	D-aminoacyl-tRNA deacylase activity
LJA35_RS19780	COG4552	Acetyltransferase involved in intracellular survival and related
LJA35_RS19785	COG2188	Transcriptional regulator
LJA35_RS19795	COG2188	Transcriptional regulator
LJA35_RS19800	COG0546	phosphoglycolate phosphatase activity
LJA35_RS19860	COG0438	transferase activity, transferring glycosyl groups
LJA35_RS19885	COG0588	phosphoglycerate mutase activity
LJA35_RS19930	COG3708	Transcriptional regulator
LJA35_RS19930	COG2207	Transcriptional regulator
LJA35_RS19960	COG5002	protein histidine kinase activity
LJA35_RS19975	COG1329	Transcriptional regulator
LJA35_RS19980	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
LJA35_RS19985	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
LJA35_RS19990	COG0215	cysteine-tRNA ligase activity
LJA35_RS20015	COG3842	ATPase activity
LJA35_RS20025	COG0596	Alpha beta hydrolase
LJA35_RS20110	COG0464	growth
LJA35_RS20125	COG1672	PFAM Archaeal ATPase
LJA35_RS20125	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
LJA35_RS20170	COG1309	transcriptional regulator
LJA35_RS20180	COG0494	nUDIX hydrolase
LJA35_RS20200	COG2197	response regulator
LJA35_RS20245	COG1940	carbohydrate kinase activity
LJA35_RS20250	COG1653	transport
LJA35_RS20270	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
LJA35_RS20280	COG0463	Glycosyl transferase, family 2
LJA35_RS20295	COG1278	Cold shock
LJA35_RS20300	COG0459	protein refolding
LJA35_RS20340	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LJA35_RS20345	COG1737	Transcriptional regulator
LJA35_RS20385	COG3973	AAA domain
LJA35_RS20395	COG1061	Type III restriction enzyme res subunit
LJA35_RS20430	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
LJA35_RS20435	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LJA35_RS20445	COG2814	Major facilitator Superfamily
LJA35_RS20460	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LJA35_RS20470	COG2252	PERMEase
LJA35_RS20500	COG0667	Aldo Keto reductase
LJA35_RS20545	COG2197	response regulator
LJA35_RS20555	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LJA35_RS20560	COG0277	FAD linked oxidase domain protein
LJA35_RS20560	COG0247	lactate metabolic process
LJA35_RS20585	COG2226	methyltransferase
LJA35_RS20600	COG2318	DinB family
LJA35_RS20630	COG0515	serine threonine protein kinase
LJA35_RS20630	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LJA35_RS20645	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LJA35_RS20660	COG0318	PFAM AMP-dependent synthetase and ligase
LJA35_RS20680	COG0259	pyridoxamine-phosphate oxidase activity
LJA35_RS20700	COG4821	SIS domain
LJA35_RS20710	COG0596	Alpha beta hydrolase
LJA35_RS20710	COG2945	thiolester hydrolase activity
LJA35_RS20720	COG1131	(ABC) transporter
LJA35_RS20780	COG1595	DNA-templated transcription, initiation
LJA35_RS20785	COG1366	Belongs to the anti-sigma-factor antagonist family
LJA35_RS20805	COG2271	Major facilitator Superfamily
LJA35_RS20815	COG2072	flavoprotein involved in K transport
LJA35_RS20825	COG0259	pyridoxamine-phosphate oxidase activity
LJA35_RS20835	COG1309	transcriptional regulator
LJA35_RS20845	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LJA35_RS20845	COG0515	serine threonine protein kinase
LJA35_RS20860	COG3629	intracellular signal transduction
LJA35_RS20860	COG3903	Transcriptional regulator
LJA35_RS20880	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
LJA35_RS20920	COG1686	Belongs to the peptidase S11 family
LJA35_RS20945	COG0386	Belongs to the glutathione peroxidase family
LJA35_RS20970	COG0110	maltose O-acetyltransferase activity
LJA35_RS20975	COG4257	antibiotic catabolic process
LJA35_RS20980	COG1309	transcriptional regulator
LJA35_RS20990	COG4941	Belongs to the sigma-70 factor family
LJA35_RS20995	COG3795	YCII-related domain
LJA35_RS21010	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LJA35_RS21020	COG0577	efflux transmembrane transporter activity
LJA35_RS21020	COG1136	(ABC) transporter
LJA35_RS21045	COG4585	Histidine kinase
LJA35_RS21100	COG1414	Transcriptional regulator
LJA35_RS21120	COG1846	Transcriptional regulator
LJA35_RS21125	COG3384	dioxygenase
LJA35_RS21130	COG1247	-acetyltransferase
LJA35_RS21135	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LJA35_RS21150	COG0477	Major facilitator Superfamily
LJA35_RS21155	COG1349	DNA-binding transcription factor activity
LJA35_RS21165	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LJA35_RS21165	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LJA35_RS21165	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LJA35_RS21195	COG1970	mechanosensitive ion channel activity
LJA35_RS21205	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LJA35_RS21230	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LJA35_RS21235	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LJA35_RS21245	COG0315	cyclic pyranopterin monophosphate synthase activity
LJA35_RS21250	COG0521	Mo-molybdopterin cofactor biosynthetic process
LJA35_RS21250	COG0315	cyclic pyranopterin monophosphate synthase activity
LJA35_RS21255	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LJA35_RS21275	COG0708	Exodeoxyribonuclease III
LJA35_RS21285	COG2072	flavoprotein involved in K transport
LJA35_RS21290	COG2267	carboxylic ester hydrolase activity
LJA35_RS21305	COG4946	Tricorn protease homolog
LJA35_RS21305	COG0793	Belongs to the peptidase S41A family
LJA35_RS21315	COG2409	Drug exporters of the RND superfamily
LJA35_RS21320	COG0442	prolyl-tRNA aminoacylation
LJA35_RS21335	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LJA35_RS21340	COG1122	ATPase activity
LJA35_RS21350	COG0310	cobalt ion transport
LJA35_RS21360	COG0768	penicillin binding
LJA35_RS21390	COG0084	hydrolase, TatD family'
LJA35_RS21395	COG1388	LysM domain
LJA35_RS21400	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LJA35_RS21405	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LJA35_RS21410	COG0488	(ABC) transporter
LJA35_RS21450	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LJA35_RS21465	COG2197	response regulator
LJA35_RS21475	COG4106	trans-aconitate 2-methyltransferase activity
LJA35_RS21485	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LJA35_RS21490	COG1309	transcriptional regulator
LJA35_RS21500	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
LJA35_RS21510	COG0193	aminoacyl-tRNA hydrolase activity
LJA35_RS21515	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LJA35_RS21520	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LJA35_RS21525	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LJA35_RS21540	COG4585	Histidine kinase
LJA35_RS21570	COG1136	(ABC) transporter
LJA35_RS21575	COG0577	efflux transmembrane transporter activity
LJA35_RS21645	COG0148	phosphopyruvate hydratase activity
LJA35_RS21665	COG1252	NADH dehydrogenase
LJA35_RS21670	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LJA35_RS21675	COG0577	efflux transmembrane transporter activity
LJA35_RS21675	COG1136	(ABC) transporter
LJA35_RS21680	COG1136	(ABC) transporter
LJA35_RS21715	COG0183	Belongs to the thiolase family
LJA35_RS21720	COG2755	lipolytic protein G-D-S-L family
LJA35_RS21755	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LJA35_RS21770	COG1228	amidohydrolase
LJA35_RS21780	COG1191	sigma factor activity
LJA35_RS21785	COG1366	Belongs to the anti-sigma-factor antagonist family
LJA35_RS21800	COG3104	oligopeptide transport
LJA35_RS21805	COG0745	RESPONSE REGULATOR receiver
LJA35_RS21810	COG2205	protein histidine kinase activity
LJA35_RS21825	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LJA35_RS21850	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LJA35_RS21870	COG1316	TRANSCRIPTIONal
LJA35_RS21885	COG1316	TRANSCRIPTIONal
LJA35_RS21890	COG1316	TRANSCRIPTIONal
LJA35_RS21895	COG1316	TRANSCRIPTIONal
LJA35_RS21900	COG1316	TRANSCRIPTIONal
LJA35_RS21905	COG1316	TRANSCRIPTIONal
LJA35_RS21930	COG0778	Nitroreductase
LJA35_RS21930	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
LJA35_RS21935	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LJA35_RS21970	COG1620	l-lactate permease
LJA35_RS21980	COG2835	tetraacyldisaccharide 4'-kinase activity
LJA35_RS21990	COG1482	cell wall glycoprotein biosynthetic process
LJA35_RS22000	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
LJA35_RS22025	COG0714	Associated with various cellular activities
LJA35_RS22050	COG0745	RESPONSE REGULATOR receiver
LJA35_RS22055	COG5000	phosphorelay sensor kinase activity
LJA35_RS22055	COG5002	protein histidine kinase activity
LJA35_RS22060	COG0823	Involved in the tonB-independent uptake of proteins
LJA35_RS22070	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LJA35_RS22075	COG2197	response regulator
LJA35_RS22080	COG3214	Protein conserved in bacteria
LJA35_RS22090	COG0653	protein targeting
LJA35_RS22110	COG2902	Dehydrogenase
LJA35_RS22115	COG1216	Glycosyl transferase, family 2
LJA35_RS22120	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LJA35_RS22125	COG1134	teichoic acid transport
LJA35_RS22155	COG1846	Transcriptional regulator
LJA35_RS22160	COG1764	response to oxidative stress
LJA35_RS22175	COG1216	Glycosyl transferase, family 2
LJA35_RS22180	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LJA35_RS22185	COG1215	transferase activity, transferring glycosyl groups
LJA35_RS22190	COG0395	ABC-type sugar transport system, permease component
LJA35_RS22195	COG1175	transmembrane transport
LJA35_RS22205	COG1674	ftsk spoiiie
LJA35_RS22210	COG0515	serine threonine protein kinase
LJA35_RS22215	COG0515	serine threonine protein kinase
LJA35_RS22220	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LJA35_RS22235	COG2884	Cell division ATP-binding protein ftsE
LJA35_RS22245	COG0793	Belongs to the peptidase S41A family
LJA35_RS22250	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LJA35_RS22265	COG0583	DNA-binding transcription factor activity
LJA35_RS22290	COG2223	nitrite transmembrane transporter activity
LJA35_RS22320	COG3973	AAA domain
LJA35_RS22330	COG0776	regulation of translation
LJA35_RS22335	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LJA35_RS22340	COG1678	Uncharacterized ACR, COG1678
LJA35_RS22355	COG1175	transmembrane transport
LJA35_RS22360	COG0395	ABC-type sugar transport system, permease component
LJA35_RS22365	COG3525	Glycosyl hydrolase, family 20, catalytic domain
LJA35_RS22380	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LJA35_RS22415	COG3480	Lon protease (S16) C-terminal proteolytic domain
LJA35_RS22425	COG1174	glycine betaine transport
LJA35_RS22445	COG3185	4-Hydroxyphenylpyruvate dioxygenase
LJA35_RS22455	COG0277	FAD linked oxidase domain protein
LJA35_RS22470	COG1714	RDD family
LJA35_RS22490	COG1335	isochorismatase
LJA35_RS22500	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LJA35_RS22510	COG1113	amino acid transport
LJA35_RS22535	COG1234	tRNA 3'-trailer cleavage
LJA35_RS22540	COG1263	PTS System
LJA35_RS22545	COG1263	PTS System
LJA35_RS22550	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LJA35_RS22555	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LJA35_RS22565	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LJA35_RS22595	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LJA35_RS22610	COG4555	ABC transporter
LJA35_RS22625	COG2733	membrane
LJA35_RS22650	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LJA35_RS22690	COG0702	epimerase
LJA35_RS22700	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LJA35_RS22735	COG1074	ATP-dependent DNA helicase activity
LJA35_RS22765	COG0270	DNA (cytosine-5-)-methyltransferase activity
LJA35_RS22850	COG4702	Belongs to the UPF0303 family
LJA35_RS22855	COG0673	inositol 2-dehydrogenase activity
LJA35_RS22870	COG2188	Transcriptional regulator
LJA35_RS22875	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LJA35_RS22920	COG0583	DNA-binding transcription factor activity
LJA35_RS22955	COG3397	chitin binding
LJA35_RS22970	COG1126	abc transporter atp-binding protein
LJA35_RS22975	COG0765	amino acid transport
LJA35_RS22980	COG0765	amino acid transport
LJA35_RS22985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LJA35_RS23000	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LJA35_RS23050	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LJA35_RS23060	COG4106	trans-aconitate 2-methyltransferase activity
LJA35_RS23115	COG0477	Major facilitator Superfamily
LJA35_RS23120	COG1012	belongs to the aldehyde dehydrogenase family
LJA35_RS23135	COG2267	carboxylic ester hydrolase activity
LJA35_RS23145	COG1028	Short-chain dehydrogenase reductase Sdr
LJA35_RS23175	COG1846	Transcriptional regulator
LJA35_RS23215	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LJA35_RS23225	COG0745	RESPONSE REGULATOR receiver
LJA35_RS23245	COG0395	ABC-type sugar transport system, permease component
LJA35_RS23270	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
LJA35_RS23275	COG4977	sequence-specific DNA binding
LJA35_RS23285	COG0589	response to stress
LJA35_RS23290	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LJA35_RS23320	COG3486	L-lysine 6-monooxygenase (NADPH) activity
LJA35_RS23340	COG1960	acyl-CoA dehydrogenase activity
LJA35_RS23355	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LJA35_RS23360	COG1309	transcriptional regulator
LJA35_RS23370	COG1946	Acyl-CoA thioesterase
LJA35_RS23385	COG0028	Belongs to the TPP enzyme family
LJA35_RS23400	COG2356	endonuclease I
LJA35_RS23435	COG1472	Belongs to the glycosyl hydrolase 3 family
LJA35_RS23460	COG1609	Transcriptional regulator
LJA35_RS23465	COG0673	inositol 2-dehydrogenase activity
LJA35_RS23480	COG1869	D-ribose catabolic process
LJA35_RS23485	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LJA35_RS23490	COG1879	ABC-type sugar transport system periplasmic component
LJA35_RS23495	COG1129	ABC transporter
LJA35_RS23510	COG1595	DNA-templated transcription, initiation
LJA35_RS23515	COG0640	Transcriptional regulator
LJA35_RS23565	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LJA35_RS23590	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LJA35_RS23620	COG1131	(ABC) transporter
LJA35_RS23680	COG0438	transferase activity, transferring glycosyl groups
LJA35_RS23700	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LJA35_RS23735	COG2304	oxidoreductase activity
LJA35_RS23750	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LJA35_RS23755	COG0456	acetyltransferase
LJA35_RS23760	COG2814	Major facilitator Superfamily
LJA35_RS23775	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LJA35_RS23790	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LJA35_RS23795	COG0629	single-stranded DNA binding
LJA35_RS23820	COG1535	isochorismatase
LJA35_RS23820	COG3433	isochorismatase activity
LJA35_RS23825	COG2378	regulation of single-species biofilm formation
LJA35_RS23855	COG1136	(ABC) transporter
LJA35_RS23855	COG0577	efflux transmembrane transporter activity
LJA35_RS23875	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LJA35_RS23905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LJA35_RS23920	COG1486	melibiose metabolic process
LJA35_RS23925	COG0395	ABC-type sugar transport system, permease component
LJA35_RS23930	COG1175	transmembrane transport
LJA35_RS23935	COG1653	transport
LJA35_RS23965	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LJA35_RS23995	COG0577	efflux transmembrane transporter activity
LJA35_RS23995	COG1136	(ABC) transporter
LJA35_RS24015	COG0668	transmembrane transport
LJA35_RS24020	COG1846	Transcriptional regulator
LJA35_RS24025	COG0697	spore germination
LJA35_RS24085	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LJA35_RS24090	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LJA35_RS24100	COG1268	BioY protein
LJA35_RS24105	COG1113	amino acid transport
LJA35_RS24110	COG0698	ribose 5-phosphate isomerase
LJA35_RS24120	COG4552	Acetyltransferase involved in intracellular survival and related
LJA35_RS24135	COG3594	Acyltransferase
LJA35_RS24155	COG0544	peptidyl-prolyl cis-trans isomerase activity
LJA35_RS24160	COG0740	serine-type endopeptidase activity
LJA35_RS24165	COG0740	serine-type endopeptidase activity
LJA35_RS24170	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LJA35_RS24180	COG0525	valine-tRNA ligase activity
LJA35_RS24185	COG0285	dihydrofolate synthase activity
LJA35_RS24195	COG0105	UTP biosynthetic process
LJA35_RS24200	COG1077	Cell shape determining protein MreB Mrl
LJA35_RS24215	COG0768	penicillin binding
LJA35_RS24220	COG0772	Belongs to the SEDS family
LJA35_RS24240	COG1530	ribonuclease E activity
LJA35_RS24245	COG0371	Dehydrogenase
LJA35_RS24250	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LJA35_RS24255	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LJA35_RS24260	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LJA35_RS24265	COG0438	transferase activity, transferring glycosyl groups
LJA35_RS24270	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LJA35_RS24275	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LJA35_RS24285	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LJA35_RS24295	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LJA35_RS24310	COG0501	Belongs to the peptidase M48B family
LJA35_RS24325	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LJA35_RS24335	COG0799	negative regulation of ribosome biogenesis
LJA35_RS24340	COG0588	phosphoglycerate mutase activity
LJA35_RS24360	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LJA35_RS24370	COG0495	leucyl-tRNA aminoacylation
LJA35_RS24380	COG1307	EDD domain protein, DegV family
LJA35_RS24385	COG1555	photosystem II stabilization
LJA35_RS24390	COG1234	tRNA 3'-trailer cleavage
LJA35_RS24400	COG0667	Aldo Keto reductase
LJA35_RS24420	COG2353	YceI-like domain
LJA35_RS24435	COG0268	Binds directly to 16S ribosomal RNA
LJA35_RS24440	COG0481	GTPase activity
LJA35_RS24470	COG1420	regulation of RNA biosynthetic process
LJA35_RS24475	COG0484	heat shock protein binding
LJA35_RS24500	COG4946	Tricorn protease homolog
LJA35_RS24500	COG0793	Belongs to the peptidase S41A family
LJA35_RS24505	COG0537	adenosine 5'-monophosphoramidase activity
LJA35_RS24510	COG1234	tRNA 3'-trailer cleavage
LJA35_RS24515	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LJA35_RS24525	COG1414	Transcriptional regulator
LJA35_RS24530	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LJA35_RS24535	COG4948	Mandelate Racemase Muconate Lactonizing
LJA35_RS24545	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LJA35_RS24550	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LJA35_RS24570	COG2315	Protein conserved in bacteria
LJA35_RS24580	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LJA35_RS24605	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LJA35_RS24650	COG2409	Drug exporters of the RND superfamily
LJA35_RS24655	COG4585	Histidine kinase
LJA35_RS24660	COG2197	response regulator
LJA35_RS24720	COG1381	Involved in DNA repair and RecF pathway recombination
LJA35_RS24725	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LJA35_RS24740	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LJA35_RS24745	COG1121	(ABC) transporter
LJA35_RS24750	COG3443	Belongs to the bacterial solute-binding protein 9 family
LJA35_RS24750	COG0803	Belongs to the bacterial solute-binding protein 9 family
LJA35_RS24755	COG0423	glycine-tRNA ligase activity
LJA35_RS24765	COG0477	Major facilitator Superfamily
LJA35_RS24800	COG0574	Belongs to the PEP-utilizing enzyme family
LJA35_RS24800	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LJA35_RS24805	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LJA35_RS24825	COG2146	nitrite reductase [NAD(P)H] activity
LJA35_RS24825	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LJA35_RS24860	COG1028	Short-chain dehydrogenase reductase Sdr
LJA35_RS24865	COG0583	DNA-binding transcription factor activity
LJA35_RS24880	COG0243	molybdopterin cofactor binding
LJA35_RS24885	COG2949	membrane
LJA35_RS24895	COG0232	Belongs to the dGTPase family. Type 2 subfamily
LJA35_RS24905	COG0358	DNA primase activity
LJA35_RS24910	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LJA35_RS24925	COG1070	Carbohydrate kinase
LJA35_RS25515	COG1077	Cell shape determining protein MreB Mrl
LJA35_RS25520	COG1404	Belongs to the peptidase S8 family
LJA35_RS25525	COG0825	malonyl-CoA metabolic process
LJA35_RS25525	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LJA35_RS25530	COG0318	PFAM AMP-dependent synthetase and ligase
LJA35_RS25540	COG2186	Transcriptional regulator
LJA35_RS25550	COG1414	Transcriptional regulator
LJA35_RS25555	COG3386	PFAM SMP-30 Gluconolaconase
LJA35_RS25585	COG1175	transmembrane transport
LJA35_RS25590	COG0395	ABC-type sugar transport system, permease component
LJA35_RS25610	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LJA35_RS25615	COG3507	Belongs to the glycosyl hydrolase 43 family
LJA35_RS25650	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LJA35_RS25675	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LJA35_RS25710	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LJA35_RS25720	COG4214	carbohydrate transport
LJA35_RS25725	COG1129	ABC transporter
LJA35_RS25760	COG2130	NADP-dependent
LJA35_RS25765	COG1764	response to oxidative stress
LJA35_RS25795	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LJA35_RS25800	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LJA35_RS25805	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LJA35_RS25810	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LJA35_RS25840	COG0789	Transcriptional regulator
LJA35_RS25845	COG0667	Aldo Keto reductase
LJA35_RS25860	COG1309	transcriptional regulator
LJA35_RS25865	COG0477	Major facilitator Superfamily
LJA35_RS25870	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
LJA35_RS25915	COG1358	cellular component organization or biogenesis
LJA35_RS25925	COG0586	Pfam SNARE associated Golgi protein
LJA35_RS25930	COG4585	Histidine kinase
LJA35_RS25935	COG2201	protein-glutamate methylesterase activity
LJA35_RS26000	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LJA35_RS26040	COG4122	O-methyltransferase activity
LJA35_RS26070	COG3409	Peptidoglycan-binding domain 1 protein
LJA35_RS26120	COG3845	ABC transporter
LJA35_RS26135	COG1657	PFAM Prenyltransferase squalene oxidase
LJA35_RS26140	COG1309	transcriptional regulator
LJA35_RS26145	COG0438	transferase activity, transferring glycosyl groups
LJA35_RS26170	COG0860	N-Acetylmuramoyl-L-alanine amidase
LJA35_RS26170	COG2247	cell wall binding repeat
LJA35_RS26180	COG0477	Major facilitator Superfamily
LJA35_RS26190	COG2197	response regulator
LJA35_RS26195	COG4585	Histidine kinase
LJA35_RS26205	COG1131	(ABC) transporter
LJA35_RS26210	COG2030	dehydratase
LJA35_RS26225	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LJA35_RS26240	COG0800	Aldolase
LJA35_RS26245	COG3022	response to hydroperoxide
LJA35_RS26290	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LJA35_RS26290	COG0515	serine threonine protein kinase
LJA35_RS26340	COG1280	lysine exporter protein (LysE YggA)
LJA35_RS26355	COG1028	Short-chain dehydrogenase reductase Sdr
LJA35_RS26380	COG2197	response regulator
LJA35_RS26400	COG0672	)-iron permease
LJA35_RS26405	COG2837	iron assimilation
LJA35_RS26415	COG1120	ATPase activity
LJA35_RS26420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LJA35_RS26445	COG0384	phenazine biosynthesis protein PhzF
LJA35_RS26485	COG1994	Peptidase M50
LJA35_RS26505	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LJA35_RS26515	COG2814	Major facilitator Superfamily
LJA35_RS26540	COG0174	glutamine synthetase
LJA35_RS26560	COG2161	toxin-antitoxin pair type II binding
LJA35_RS26565	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LJA35_RS26575	COG1609	Transcriptional regulator
LJA35_RS26585	COG1175	transmembrane transport
LJA35_RS26590	COG3833	ABC-type maltose transport systems, permease component
LJA35_RS26595	COG0366	Alpha amylase catalytic
LJA35_RS26615	COG1309	transcriptional regulator
LJA35_RS26645	COG2197	response regulator
LJA35_RS26660	COG0745	RESPONSE REGULATOR receiver
LJA35_RS26715	COG0501	Belongs to the peptidase M48B family
LJA35_RS26720	COG1733	regulation of RNA biosynthetic process
LJA35_RS26725	COG0702	epimerase
LJA35_RS26735	COG0174	glutamine synthetase
LJA35_RS26755	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LJA35_RS26760	COG0321	lipoyl(octanoyl) transferase activity
LJA35_RS26805	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
LJA35_RS26815	COG0508	dehydrogenase complex catalyzes the overall conversion of
LJA35_RS26820	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LJA35_RS26825	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LJA35_RS26835	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
LJA35_RS26845	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
LJA35_RS26865	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LJA35_RS26870	COG2226	methyltransferase
LJA35_RS26890	COG4585	Histidine kinase
LJA35_RS26895	COG2197	response regulator
LJA35_RS26900	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LJA35_RS26910	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LJA35_RS26930	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LJA35_RS26940	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LJA35_RS26945	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LJA35_RS26955	COG1376	ErfK ybiS ycfS ynhG family protein
LJA35_RS26965	COG1845	cytochrome c oxidase, subunit III
LJA35_RS26970	COG2010	Cytochrome c
LJA35_RS26975	COG0723	plastoquinol--plastocyanin reductase activity
LJA35_RS26980	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LJA35_RS26985	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LJA35_RS26990	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LJA35_RS26995	COG1929	Belongs to the glycerate kinase type-1 family
LJA35_RS27005	COG0745	RESPONSE REGULATOR receiver
LJA35_RS27010	COG2205	protein histidine kinase activity
LJA35_RS27060	COG0438	transferase activity, transferring glycosyl groups
LJA35_RS27080	COG0003	Pfam Anion-transporting ATPase
LJA35_RS27090	COG1940	carbohydrate kinase activity
LJA35_RS27115	COG4585	Histidine kinase
LJA35_RS27120	COG2197	response regulator
LJA35_RS27125	COG0205	6-phosphofructokinase activity
LJA35_RS27130	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LJA35_RS27145	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
LJA35_RS27155	COG2193	ferroxidase activity
LJA35_RS27160	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LJA35_RS27165	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LJA35_RS27170	COG2815	serine threonine protein kinase
LJA35_RS27170	COG0515	serine threonine protein kinase
LJA35_RS27175	COG2022	thiamine diphosphate biosynthetic process
LJA35_RS27185	COG2022	thiamine diphosphate biosynthetic process
LJA35_RS27185	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LJA35_RS27200	COG0352	thiamine-phosphate diphosphorylase activity
LJA35_RS27220	COG1309	transcriptional regulator
LJA35_RS27250	COG0714	Associated with various cellular activities
LJA35_RS27260	COG0275	rRNA processing
LJA35_RS27270	COG0768	penicillin binding
LJA35_RS27275	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LJA35_RS27280	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LJA35_RS27285	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LJA35_RS27290	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LJA35_RS27300	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LJA35_RS27305	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LJA35_RS27310	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LJA35_RS27315	COG1496	oxidoreductase activity
LJA35_RS27325	COG1799	cell septum assembly
LJA35_RS27335	COG3599	regulation of cell shape
LJA35_RS27340	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LJA35_RS27350	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LJA35_RS27365	COG0025	NhaP-type Na H and K H
LJA35_RS27400	COG0587	DNA-directed DNA polymerase activity
LJA35_RS27410	COG1432	Conserved Protein
LJA35_RS27430	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LJA35_RS27450	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LJA35_RS27455	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LJA35_RS27460	COG0131	Imidazoleglycerol-phosphate dehydratase
LJA35_RS27470	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LJA35_RS27475	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LJA35_RS27480	COG0251	oxidation-reduction process
LJA35_RS27485	COG0107	imidazoleglycerol-phosphate synthase activity
LJA35_RS27510	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LJA35_RS27535	COG0134	indole-3-glycerol-phosphate synthase activity
LJA35_RS27540	COG0133	tryptophan synthase activity
LJA35_RS27545	COG0159	tryptophan synthase activity
LJA35_RS27555	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LJA35_RS27560	COG2301	Belongs to the HpcH HpaI aldolase family
LJA35_RS27565	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LJA35_RS27600	COG0069	glutamate synthase activity
LJA35_RS27600	COG0070	glutamate synthase
LJA35_RS27600	COG0067	glutamate synthase
LJA35_RS27620	COG2304	oxidoreductase activity
LJA35_RS27625	COG2968	Membrane
LJA35_RS27635	COG0287	Prephenate dehydrogenase
LJA35_RS27635	COG1605	Chorismate mutase
LJA35_RS27655	COG0737	Belongs to the 5'-nucleotidase family
LJA35_RS27710	COG2050	protein possibly involved in aromatic compounds catabolism
LJA35_RS27735	COG1643	Atp-dependent helicase
LJA35_RS27745	COG0539	negative regulation of cytoplasmic translation
LJA35_RS27755	COG0237	dephospho-CoA kinase activity
LJA35_RS27770	COG2226	methyltransferase
LJA35_RS27790	COG2267	carboxylic ester hydrolase activity
LJA35_RS27810	COG0402	S-adenosylhomocysteine deaminase activity
LJA35_RS27860	COG2226	methyltransferase
LJA35_RS27870	COG2313	pseudouridylate synthase activity
LJA35_RS27880	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LJA35_RS27885	COG0584	glycerophosphoryl diester phosphodiesterase
LJA35_RS27895	COG0556	nucleotide-excision repair
LJA35_RS27915	COG0387	Pfam Sodium calcium exchanger
LJA35_RS27920	COG1619	proteins homologs of microcin C7 resistance protein MccF
LJA35_RS27925	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LJA35_RS27940	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LJA35_RS27945	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LJA35_RS27965	COG0322	excinuclease ABC activity
LJA35_RS27970	COG1660	Displays ATPase and GTPase activities
LJA35_RS27975	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LJA35_RS27980	COG1481	regulation of sporulation
LJA35_RS27990	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LJA35_RS27995	COG0126	phosphoglycerate kinase activity
LJA35_RS28000	COG0149	triose-phosphate isomerase activity
LJA35_RS28005	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LJA35_RS28015	COG0166	Belongs to the GPI family
LJA35_RS28025	COG1136	(ABC) transporter
LJA35_RS28030	COG1695	Transcriptional regulator
LJA35_RS28035	COG1653	transport
LJA35_RS28040	COG0366	Alpha amylase catalytic
LJA35_RS28045	COG1653	transport
LJA35_RS28050	COG1175	transmembrane transport
LJA35_RS28055	COG0395	ABC-type sugar transport system, permease component
LJA35_RS28060	COG0363	glucosamine-6-phosphate deaminase activity
LJA35_RS28075	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LJA35_RS28085	COG0109	protoheme IX farnesyltransferase activity
LJA35_RS28115	COG1131	(ABC) transporter
LJA35_RS28120	COG2746	aminoglycoside 3-N-acetyltransferase activity
LJA35_RS28135	COG0719	Fe-S assembly protein
LJA35_RS28145	COG0396	ATPase activity
LJA35_RS28150	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LJA35_RS28155	COG0822	iron-sulfur transferase activity
LJA35_RS28160	COG2151	metal-sulfur cluster biosynthetic enzyme
LJA35_RS28165	COG2076	Multidrug Resistance protein
LJA35_RS28170	COG3226	Transcriptional regulator
LJA35_RS28175	COG2171	N-acyltransferase activity
LJA35_RS28185	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LJA35_RS28225	COG1802	Transcriptional regulator
LJA35_RS28235	COG1309	transcriptional regulator
LJA35_RS28250	COG1063	alcohol dehydrogenase
LJA35_RS28270	COG1349	DNA-binding transcription factor activity
LJA35_RS28275	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LJA35_RS28280	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LJA35_RS28305	COG1802	Transcriptional regulator
LJA35_RS28320	COG1175	transmembrane transport
LJA35_RS28325	COG0395	ABC-type sugar transport system, permease component
LJA35_RS28340	COG3507	Belongs to the glycosyl hydrolase 43 family
LJA35_RS28350	COG2755	lipolytic protein G-D-S-L family
LJA35_RS28355	COG3866	Pectate lyase
LJA35_RS28360	COG4677	pectinesterase activity
LJA35_RS28370	COG3507	Belongs to the glycosyl hydrolase 43 family
LJA35_RS28380	COG1595	DNA-templated transcription, initiation
LJA35_RS28385	COG0768	penicillin binding
LJA35_RS28395	COG4585	Histidine kinase
LJA35_RS28410	COG1414	Transcriptional regulator
LJA35_RS28435	COG5285	phytanoyl-CoA dioxygenase
LJA35_RS28440	COG1917	Cupin 2, conserved barrel domain protein
LJA35_RS28445	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LJA35_RS28450	COG0456	acetyltransferase
LJA35_RS28455	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LJA35_RS28480	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
LJA35_RS28510	COG1797	cobyrinic acid a,c-diamide synthase activity
LJA35_RS28530	COG1492	cobalamin metabolic process
LJA35_RS28535	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
LJA35_RS28550	COG0235	Class ii aldolase
LJA35_RS28570	COG0488	(ABC) transporter
LJA35_RS28580	COG1024	Enoyl-CoA hydratase
LJA35_RS28615	COG3387	PFAM Glycoside hydrolase 15-related
LJA35_RS28640	COG1404	Belongs to the peptidase S8 family
LJA35_RS28650	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LJA35_RS28655	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LJA35_RS28675	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LJA35_RS28690	COG1028	Short-chain dehydrogenase reductase Sdr
LJA35_RS28700	COG2186	Transcriptional regulator
LJA35_RS28720	COG0560	Phosphoserine phosphatase
LJA35_RS28720	COG3830	Belongs to the UPF0237 family
LJA35_RS28730	COG0842	Transport permease protein
LJA35_RS28730	COG1131	(ABC) transporter
LJA35_RS28730	COG1716	ATPase activity
LJA35_RS28740	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LJA35_RS28745	COG4221	oxidoreductase activity
LJA35_RS28750	COG4585	Histidine kinase
LJA35_RS28755	COG2197	response regulator
LJA35_RS28770	COG1119	ATPase activity
LJA35_RS28790	COG1881	PFAM PEBP family protein
LJA35_RS28800	COG2094	Belongs to the DNA glycosylase MPG family
LJA35_RS28820	COG0647	UMP catabolic process
LJA35_RS28825	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LJA35_RS28830	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LJA35_RS28835	COG1120	ATPase activity
LJA35_RS28855	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LJA35_RS28860	COG0497	DNA recombination
LJA35_RS28865	COG0297	glycogen (starch) synthase activity
LJA35_RS28875	COG3387	PFAM Glycoside hydrolase 15-related
LJA35_RS28880	COG0504	CTP synthase activity
LJA35_RS28885	COG0494	nUDIX hydrolase
LJA35_RS28895	COG0686	Belongs to the AlaDH PNT family
LJA35_RS28910	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LJA35_RS28915	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LJA35_RS28920	COG1187	pseudouridine synthase activity
LJA35_RS28930	COG1397	ADP-ribosylglycohydrolase
LJA35_RS28935	COG3541	Predicted nucleotidyltransferase
LJA35_RS28960	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LJA35_RS28970	COG1160	GTP binding
LJA35_RS28995	COG0671	phosphoesterase, PA-phosphatase related
LJA35_RS29005	COG0477	Major facilitator Superfamily
LJA35_RS29010	COG1960	acyl-CoA dehydrogenase activity
LJA35_RS29015	COG1799	cell septum assembly
LJA35_RS29035	COG4585	Histidine kinase
LJA35_RS29045	COG1131	(ABC) transporter
LJA35_RS29060	COG0587	DNA-directed DNA polymerase activity
LJA35_RS29070	COG0662	Cupin 2, conserved barrel domain protein
LJA35_RS29070	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LJA35_RS29095	COG2226	methyltransferase
LJA35_RS29110	COG1725	Transcriptional regulator
LJA35_RS29125	COG2755	lipolytic protein G-D-S-L family
LJA35_RS29130	COG1595	DNA-templated transcription, initiation
LJA35_RS29165	COG2188	Transcriptional regulator
LJA35_RS29170	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
LJA35_RS29180	COG1309	transcriptional regulator
LJA35_RS29185	COG0243	molybdopterin cofactor binding
LJA35_RS29190	COG2851	Citrate transporter
LJA35_RS29205	COG3842	ATPase activity
LJA35_RS29225	COG0640	Transcriptional regulator
LJA35_RS29235	COG1960	acyl-CoA dehydrogenase activity
LJA35_RS29275	COG3876	Protein conserved in bacteria
LJA35_RS29290	COG0583	DNA-binding transcription factor activity
LJA35_RS29310	COG2149	membrane
LJA35_RS29315	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
LJA35_RS29335	COG1063	alcohol dehydrogenase
LJA35_RS29340	COG1028	Short-chain dehydrogenase reductase Sdr
LJA35_RS29350	COG3265	gluconokinase activity
LJA35_RS29355	COG2186	Transcriptional regulator
LJA35_RS29360	COG3012	SEC-C Motif Domain Protein
LJA35_RS29370	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LJA35_RS29400	COG0667	Aldo Keto reductase
LJA35_RS29405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LJA35_RS29415	COG0598	Magnesium transport protein CorA
LJA35_RS29420	COG0588	phosphoglycerate mutase activity
LJA35_RS29435	COG0215	cysteine-tRNA ligase activity
LJA35_RS29445	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LJA35_RS29450	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LJA35_RS29455	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LJA35_RS29460	COG1414	Transcriptional regulator
LJA35_RS29465	COG1410	methionine synthase
LJA35_RS29465	COG0646	methionine synthase
LJA35_RS29470	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LJA35_RS29475	COG4166	transmembrane transport
LJA35_RS29480	COG2197	response regulator
LJA35_RS29490	COG1994	Peptidase M50
LJA35_RS29490	COG0517	IMP dehydrogenase activity
LJA35_RS29510	COG1222	aaa ATPase
LJA35_RS29515	COG4122	O-methyltransferase activity
LJA35_RS29530	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
LJA35_RS29535	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
LJA35_RS29540	COG1609	Transcriptional regulator
LJA35_RS29550	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
LJA35_RS29555	COG0545	Peptidyl-prolyl cis-trans isomerase
LJA35_RS29585	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LJA35_RS29590	COG0805	protein transport
LJA35_RS29625	COG0564	pseudouridine synthase activity
LJA35_RS29640	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LJA35_RS29645	COG4175	Glycine betaine
LJA35_RS29645	COG0517	IMP dehydrogenase activity
LJA35_RS29650	COG4176	ABC-type proline glycine betaine transport system permease component
LJA35_RS29675	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LJA35_RS29685	COG0174	glutamine synthetase
LJA35_RS29690	COG1012	belongs to the aldehyde dehydrogenase family
LJA35_RS29735	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LJA35_RS29740	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LJA35_RS29745	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LJA35_RS29750	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LJA35_RS29755	COG5002	protein histidine kinase activity
LJA35_RS29760	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LJA35_RS29765	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LJA35_RS29765	COG0072	phenylalanine-tRNA ligase activity
LJA35_RS29785	COG1649	PFAM Uncharacterised BCR, COG1649
LJA35_RS29795	COG0697	spore germination
LJA35_RS29825	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LJA35_RS29830	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LJA35_RS29835	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LJA35_RS29840	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LJA35_RS29845	COG1438	arginine binding
LJA35_RS29880	COG0165	Argininosuccinate lyase
LJA35_RS29895	COG0477	Major facilitator Superfamily
LJA35_RS29905	COG0584	glycerophosphoryl diester phosphodiesterase
LJA35_RS29935	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LJA35_RS29940	COG2011	ABC-type metal ion transport system permease component
LJA35_RS29945	COG1464	Belongs to the NlpA lipoprotein family
LJA35_RS29960	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
LJA35_RS29965	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LJA35_RS29965	COG1648	precorrin-2 dehydrogenase activity
LJA35_RS30020	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LJA35_RS30075	COG1175	transmembrane transport
LJA35_RS30080	COG0395	ABC-type sugar transport system, permease component
LJA35_RS30105	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LJA35_RS30120	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LJA35_RS30140	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LJA35_RS30145	COG1560	Kdo2-lipid A biosynthetic process
LJA35_RS30150	COG0438	transferase activity, transferring glycosyl groups
LJA35_RS30160	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
LJA35_RS30165	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
LJA35_RS30170	COG0217	transcriptional regulatory protein
LJA35_RS30175	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LJA35_RS30180	COG0632	four-way junction helicase activity
LJA35_RS30185	COG2255	four-way junction helicase activity
LJA35_RS30195	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LJA35_RS30200	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LJA35_RS30205	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LJA35_RS30210	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LJA35_RS30215	COG1196	nuclear chromosome segregation
LJA35_RS30220	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LJA35_RS30230	COG0124	histidyl-tRNA synthetase
LJA35_RS30245	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LJA35_RS30265	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LJA35_RS30270	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LJA35_RS30280	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LJA35_RS30285	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LJA35_RS30290	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LJA35_RS30295	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LJA35_RS30305	COG0006	proline dipeptidase activity
LJA35_RS30310	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LJA35_RS30315	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LJA35_RS30325	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LJA35_RS30330	COG0540	Belongs to the ATCase OTCase family
LJA35_RS30335	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LJA35_RS30345	COG0505	Belongs to the CarA family
LJA35_RS30350	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LJA35_RS30355	COG0167	dihydroorotate dehydrogenase activity
LJA35_RS30360	COG0284	orotidine-5'-phosphate decarboxylase activity
LJA35_RS30370	COG0194	GDP metabolic process
LJA35_RS30375	COG1758	RNA polymerase activity
LJA35_RS30385	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LJA35_RS30400	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LJA35_RS30420	COG0515	serine threonine protein kinase
LJA35_RS30435	COG1653	transport
LJA35_RS30440	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LJA35_RS30445	COG2390	Transcriptional regulator
LJA35_RS30465	COG0531	amino acid
LJA35_RS30485	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LJA35_RS30510	COG2233	PERMEase
LJA35_RS30520	COG2223	nitrite transmembrane transporter activity
LJA35_RS30525	COG1846	Transcriptional regulator
LJA35_RS30545	COG3201	nicotinamide mononucleotide transporter
LJA35_RS30550	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LJA35_RS30550	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LJA35_RS30555	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LJA35_RS30560	COG0140	phosphoribosyl-ATP diphosphatase activity
LJA35_RS30565	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LJA35_RS30615	COG1960	acyl-CoA dehydrogenase activity
LJA35_RS30640	COG0463	Glycosyl transferase, family 2
LJA35_RS30655	COG2270	Major facilitator Superfamily
LJA35_RS30665	COG2364	Membrane
LJA35_RS30695	COG4336	lyase activity
LJA35_RS30700	COG2814	Major facilitator Superfamily
LJA35_RS30730	COG0326	Molecular chaperone. Has ATPase activity
LJA35_RS30750	COG2018	Roadblock/LC7 domain
LJA35_RS30765	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
LJA35_RS30780	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LJA35_RS30790	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LJA35_RS30805	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LJA35_RS30825	COG1716	ATPase activity
LJA35_RS30845	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LJA35_RS30855	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LJA35_RS30855	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LJA35_RS30875	COG0725	ABC transporter, periplasmic molybdate-binding protein
LJA35_RS30885	COG1609	Transcriptional regulator
LJA35_RS30910	COG0384	phenazine biosynthesis protein PhzF
LJA35_RS30915	COG2197	response regulator
LJA35_RS30920	COG4585	Histidine kinase
LJA35_RS30930	COG0577	efflux transmembrane transporter activity
LJA35_RS30930	COG1136	(ABC) transporter
LJA35_RS30970	COG0697	spore germination
LJA35_RS30985	COG0723	plastoquinol--plastocyanin reductase activity
LJA35_RS31025	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LJA35_RS31040	COG2318	DinB family
LJA35_RS31060	COG0815	Transfers the fatty acyl group on membrane lipoproteins
LJA35_RS31065	COG1028	Short-chain dehydrogenase reductase Sdr
LJA35_RS31110	COG1968	undecaprenyl-diphosphatase activity
LJA35_RS31125	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LJA35_RS31160	COG0110	maltose O-acetyltransferase activity
LJA35_RS31180	COG0640	Transcriptional regulator
LJA35_RS31185	COG1832	CoA-binding protein
LJA35_RS31195	COG1739	Uncharacterized protein family UPF0029
LJA35_RS31230	COG0420	3'-5' exonuclease activity
LJA35_RS31235	COG0419	ATPase involved in DNA repair
LJA35_RS31240	COG1522	sequence-specific DNA binding
LJA35_RS31255	COG1028	Short-chain dehydrogenase reductase Sdr
LJA35_RS31270	COG0626	cystathionine gamma-synthase activity
LJA35_RS31350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LJA35_RS31390	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
LJA35_RS31390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LJA35_RS31400	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
LJA35_RS31405	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LJA35_RS31430	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LJA35_RS31430	COG3320	Male sterility
LJA35_RS31435	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LJA35_RS31440	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LJA35_RS31445	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LJA35_RS31450	COG0022	dehydrogenase e1 component
LJA35_RS31455	COG0508	dehydrogenase complex catalyzes the overall conversion of
LJA35_RS31460	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LJA35_RS31465	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LJA35_RS31475	COG2267	carboxylic ester hydrolase activity
LJA35_RS31480	COG1595	DNA-templated transcription, initiation
LJA35_RS31485	COG2188	Transcriptional regulator
LJA35_RS31490	COG1940	carbohydrate kinase activity
LJA35_RS31495	COG2197	response regulator
LJA35_RS31500	COG4585	Histidine kinase
LJA35_RS31520	COG3663	DNA glycosylase
LJA35_RS31525	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LJA35_RS31545	COG0456	acetyltransferase
LJA35_RS31565	COG2226	methyltransferase
LJA35_RS31570	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LJA35_RS31575	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LJA35_RS31580	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LJA35_RS31585	COG0156	8-amino-7-oxononanoate synthase activity
LJA35_RS31610	COG0831	urea catabolic process
LJA35_RS31615	COG0832	Belongs to the urease beta subunit family
LJA35_RS31620	COG0804	urea catabolic process
LJA35_RS31630	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
LJA35_RS31635	COG0829	nickel cation binding
LJA35_RS31650	COG0204	Acyl-transferase
LJA35_RS31675	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LJA35_RS31680	COG1834	amidinotransferase
LJA35_RS31685	COG1522	sequence-specific DNA binding
LJA35_RS31700	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LJA35_RS31705	COG3275	phosphorelay sensor kinase activity
LJA35_RS31720	COG0205	6-phosphofructokinase activity
LJA35_RS31725	COG3442	glutamine amidotransferase
LJA35_RS31730	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LJA35_RS31735	COG0242	peptide deformylase activity
LJA35_RS31745	COG1960	acyl-CoA dehydrogenase activity
LJA35_RS31755	COG2124	cytochrome p450
LJA35_RS31760	COG3424	synthase
LJA35_RS31770	COG1012	belongs to the aldehyde dehydrogenase family
LJA35_RS31780	COG1793	dna ligase
LJA35_RS31790	COG1396	sequence-specific DNA binding
LJA35_RS31790	COG3800	Transcriptional regulator
LJA35_RS31800	COG1960	acyl-CoA dehydrogenase activity
LJA35_RS31805	COG1960	acyl-CoA dehydrogenase activity
LJA35_RS31830	COG0477	Major facilitator Superfamily
LJA35_RS31880	COG1012	belongs to the aldehyde dehydrogenase family
LJA35_RS31895	COG1846	Transcriptional regulator
LJA35_RS31895	COG1940	carbohydrate kinase activity
LJA35_RS31900	COG1070	Carbohydrate kinase
LJA35_RS31905	COG2115	Belongs to the xylose isomerase family
LJA35_RS31915	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LJA35_RS31975	COG2018	Roadblock/LC7 domain
LJA35_RS31985	COG1946	Acyl-CoA thioesterase
LJA35_RS32000	COG0254	rRNA binding
LJA35_RS32010	COG1132	(ABC) transporter
LJA35_RS32015	COG1132	(ABC) transporter
LJA35_RS32030	COG1132	(ABC) transporter
LJA35_RS32040	COG2072	flavoprotein involved in K transport
LJA35_RS32045	COG0432	Pfam Uncharacterised protein family UPF0047
LJA35_RS32070	COG3290	protein histidine kinase activity
LJA35_RS32075	COG4565	transcriptional regulatory protein
LJA35_RS32085	COG2080	2 iron, 2 sulfur cluster binding
LJA35_RS32090	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
LJA35_RS32095	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LJA35_RS32105	COG3387	PFAM Glycoside hydrolase 15-related
LJA35_RS32120	COG4221	oxidoreductase activity
LJA35_RS32155	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LJA35_RS32170	COG2706	6-phosphogluconolactonase activity
LJA35_RS32180	COG2971	BadF BadG BcrA BcrD
LJA35_RS32185	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LJA35_RS32195	COG1960	acyl-CoA dehydrogenase activity
LJA35_RS32210	COG1902	pentaerythritol trinitrate reductase activity
LJA35_RS32215	COG0640	Transcriptional regulator
LJA35_RS32235	COG1309	transcriptional regulator
LJA35_RS32245	COG0671	phosphoesterase, PA-phosphatase related
LJA35_RS32285	COG0584	glycerophosphoryl diester phosphodiesterase
LJA35_RS32310	COG0204	Acyl-transferase
LJA35_RS32330	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LJA35_RS32360	COG1660	Displays ATPase and GTPase activities
LJA35_RS32365	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LJA35_RS32375	COG0445	tRNA wobble uridine modification
LJA35_RS32380	COG4585	Histidine kinase
LJA35_RS32385	COG2197	response regulator
LJA35_RS32405	COG0738	Major facilitator superfamily
LJA35_RS32410	COG1609	Transcriptional regulator
LJA35_RS32420	COG1175	transmembrane transport
LJA35_RS32425	COG0395	ABC-type sugar transport system, permease component
LJA35_RS32430	COG3250	beta-galactosidase activity
LJA35_RS32440	COG2723	6-phospho-beta-galactosidase activity
LJA35_RS32445	COG0395	ABC-type sugar transport system, permease component
LJA35_RS32450	COG1175	transmembrane transport
LJA35_RS32460	COG1501	Belongs to the glycosyl hydrolase 31 family
LJA35_RS32475	COG0783	Belongs to the Dps family
LJA35_RS32480	COG0673	inositol 2-dehydrogenase activity
LJA35_RS32500	COG2608	mercury ion transmembrane transporter activity
LJA35_RS32515	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LJA35_RS32520	COG0191	fructose-bisphosphate aldolase activity
LJA35_RS32525	COG2813	Specifically methylates the guanine in position
LJA35_RS32535	COG1940	carbohydrate kinase activity
LJA35_RS32570	COG1136	(ABC) transporter
LJA35_RS32575	COG0577	efflux transmembrane transporter activity
LJA35_RS32590	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LJA35_RS32600	COG1349	DNA-binding transcription factor activity
LJA35_RS32640	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LJA35_RS32660	COG3345	alpha-galactosidase
LJA35_RS32675	COG1609	Transcriptional regulator
LJA35_RS32685	COG1175	transmembrane transport
LJA35_RS32695	COG1472	Belongs to the glycosyl hydrolase 3 family
LJA35_RS32710	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LJA35_RS32720	COG0137	argininosuccinate synthase activity
LJA35_RS32740	COG0444	Belongs to the ABC transporter superfamily
LJA35_RS32750	COG0747	negative chemotaxis
LJA35_RS32760	COG3458	cephalosporin-C deacetylase activity
LJA35_RS32770	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LJA35_RS32780	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
LJA35_RS32800	COG0640	Transcriptional regulator
LJA35_RS32805	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LJA35_RS32810	COG1993	acr, cog1993
LJA35_RS32815	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LJA35_RS32820	COG1968	undecaprenyl-diphosphatase activity
LJA35_RS32830	COG2066	Belongs to the glutaminase family
LJA35_RS32840	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LJA35_RS32855	COG2226	methyltransferase
LJA35_RS32860	COG2188	Transcriptional regulator
LJA35_RS32865	COG3458	cephalosporin-C deacetylase activity
LJA35_RS32880	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LJA35_RS32890	COG2890	protein-(glutamine-N5) methyltransferase activity
LJA35_RS32910	COG0446	pyridine nucleotide-disulphide oxidoreductase
LJA35_RS32910	COG1902	pentaerythritol trinitrate reductase activity
LJA35_RS32940	COG1461	Dihydroxyacetone kinase
LJA35_RS32945	COG2376	Dihydroxyacetone kinase
LJA35_RS32965	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LJA35_RS32965	COG1017	nitric oxide dioxygenase activity
LJA35_RS33020	COG1595	DNA-templated transcription, initiation
LJA35_RS33040	COG1053	succinate dehydrogenase
LJA35_RS33050	COG1764	response to oxidative stress
LJA35_RS33055	COG1595	DNA-templated transcription, initiation
LJA35_RS33095	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LJA35_RS33115	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
LJA35_RS33135	COG0477	Major facilitator Superfamily
LJA35_RS33165	COG1672	PFAM Archaeal ATPase
LJA35_RS33165	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
LJA35_RS33180	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
LJA35_RS33180	COG1672	PFAM Archaeal ATPase
LJA35_RS33200	COG0778	Nitroreductase
LJA35_RS33215	COG1595	DNA-templated transcription, initiation
LJA35_RS33220	COG1846	Transcriptional regulator
LJA35_RS33225	COG0640	Transcriptional regulator
LJA35_RS33250	COG0477	Major facilitator Superfamily
LJA35_RS33255	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LJA35_RS33275	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
LJA35_RS33275	COG1672	PFAM Archaeal ATPase
LJA35_RS33340	COG2837	iron assimilation
LJA35_RS33365	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LJA35_RS33375	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LJA35_RS33435	COG0745	RESPONSE REGULATOR receiver
LJA35_RS33440	COG2205	protein histidine kinase activity
LJA35_RS33450	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LJA35_RS33460	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LJA35_RS33485	COG0515	serine threonine protein kinase
LJA35_RS33500	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LJA35_RS33505	COG0318	PFAM AMP-dependent synthetase and ligase
LJA35_RS33550	COG0673	inositol 2-dehydrogenase activity
LJA35_RS33600	COG0346	lactoylglutathione lyase activity
LJA35_RS33605	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LJA35_RS33615	COG0583	DNA-binding transcription factor activity
LJA35_RS33620	COG0667	Aldo Keto reductase
LJA35_RS33650	COG1191	sigma factor activity
LJA35_RS33655	COG1396	sequence-specific DNA binding
LJA35_RS33660	COG0740	serine-type endopeptidase activity
LJA35_RS33665	COG0740	serine-type endopeptidase activity
LJA35_RS33680	COG0328	RNA-DNA hybrid ribonuclease activity
LJA35_RS33690	COG0667	Aldo Keto reductase
LJA35_RS33710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LJA35_RS33715	COG0515	serine threonine protein kinase
LJA35_RS33720	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LJA35_RS33730	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
LJA35_RS33730	COG1672	PFAM Archaeal ATPase
LJA35_RS33760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LJA35_RS33795	COG0477	Major facilitator Superfamily
LJA35_RS33805	COG1982	Orn Lys Arg decarboxylase major
LJA35_RS33845	COG1252	NADH dehydrogenase
LJA35_RS33860	COG2172	sigma factor antagonist activity
LJA35_RS33865	COG1366	Belongs to the anti-sigma-factor antagonist family
LJA35_RS33870	COG1366	Belongs to the anti-sigma-factor antagonist family
LJA35_RS33885	COG0784	Response regulator, receiver
LJA35_RS33885	COG5002	protein histidine kinase activity
LJA35_RS33885	COG2205	protein histidine kinase activity
LJA35_RS33915	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
LJA35_RS33920	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LJA35_RS33935	COG0366	Alpha amylase catalytic
LJA35_RS33965	COG1191	sigma factor activity
LJA35_RS33975	COG0181	hydroxymethylbilane synthase activity
LJA35_RS33985	COG1793	dna ligase
LJA35_RS33985	COG3285	dna ligase
LJA35_RS34010	COG2208	phosphoserine phosphatase activity
LJA35_RS34020	COG0656	L-ascorbic acid biosynthetic process
LJA35_RS34035	COG0009	L-threonylcarbamoyladenylate synthase
LJA35_RS34090	COG1088	dTDP-glucose 4,6-dehydratase activity
LJA35_RS34105	COG0456	acetyltransferase
LJA35_RS34140	COG2124	cytochrome p450
LJA35_RS34145	COG0142	geranyltranstransferase activity
LJA35_RS34155	COG1131	(ABC) transporter
LJA35_RS34180	COG0475	glutathione-regulated potassium exporter activity
LJA35_RS34205	COG1028	Short-chain dehydrogenase reductase Sdr
LJA35_RS34210	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
LJA35_RS34275	COG1120	ATPase activity
LJA35_RS34300	COG0110	maltose O-acetyltransferase activity
LJA35_RS34320	COG0395	ABC-type sugar transport system, permease component
LJA35_RS34325	COG4209	transmembrane transport
LJA35_RS34335	COG0028	Belongs to the TPP enzyme family
LJA35_RS34340	COG1028	Short-chain dehydrogenase reductase Sdr
LJA35_RS34365	COG2814	Major facilitator Superfamily
LJA35_RS34375	COG1959	2 iron, 2 sulfur cluster binding
LJA35_RS34395	COG5640	endopeptidase activity
LJA35_RS34400	COG0583	DNA-binding transcription factor activity
LJA35_RS34410	COG2814	Major facilitator Superfamily
LJA35_RS34425	COG0583	DNA-binding transcription factor activity
LJA35_RS34430	COG3340	Belongs to the peptidase S51 family
LJA35_RS34445	COG2124	cytochrome p450
LJA35_RS34500	COG1335	isochorismatase
LJA35_RS34515	COG1119	ATPase activity
LJA35_RS34525	COG5640	endopeptidase activity
LJA35_RS34575	COG2050	protein possibly involved in aromatic compounds catabolism
LJA35_RS34580	COG3396	Phenylacetate-CoA oxygenase
LJA35_RS34585	COG3460	Phenylacetate-CoA oxygenase
LJA35_RS34590	COG3396	Phenylacetate-CoA oxygenase
LJA35_RS34595	COG2151	metal-sulfur cluster biosynthetic enzyme
LJA35_RS34600	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LJA35_RS34650	COG1953	Uracil, thiamine, allantoin
LJA35_RS34665	COG1175	transmembrane transport
LJA35_RS34670	COG0395	ABC-type sugar transport system, permease component
LJA35_RS34680	COG2175	clavaminate synthase activity
LJA35_RS34705	COG4977	sequence-specific DNA binding
LJA35_RS34710	COG2755	lipolytic protein G-D-S-L family
LJA35_RS34715	COG0326	Molecular chaperone. Has ATPase activity
LJA35_RS34725	COG3226	Transcriptional regulator
LJA35_RS34740	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LJA35_RS34775	COG2409	Drug exporters of the RND superfamily
LJA35_RS34780	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LJA35_RS34790	COG0517	IMP dehydrogenase activity
LJA35_RS34790	COG0516	GMP reductase activity
LJA35_RS34825	COG3119	arylsulfatase activity
LJA35_RS34830	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LJA35_RS34835	COG0584	glycerophosphoryl diester phosphodiesterase
LJA35_RS34870	COG0395	ABC-type sugar transport system, permease component
LJA35_RS34885	COG1051	belongs to the nudix hydrolase family
LJA35_RS34890	COG0584	glycerophosphoryl diester phosphodiesterase
LJA35_RS34900	COG1366	Belongs to the anti-sigma-factor antagonist family
LJA35_RS34945	COG3250	beta-galactosidase activity
LJA35_RS34945	COG5297	Belongs to the glycosyl hydrolase family 6
LJA35_RS34985	COG0667	Aldo Keto reductase
LJA35_RS34990	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
LJA35_RS34995	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LJA35_RS35005	COG1737	Transcriptional regulator
LJA35_RS35010	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LJA35_RS35020	COG0154	amidase activity
LJA35_RS35025	COG1309	transcriptional regulator
LJA35_RS35070	COG2353	YceI-like domain
LJA35_RS35095	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
LJA35_RS35100	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
LJA35_RS35115	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LJA35_RS35125	COG5640	endopeptidase activity
LJA35_RS35175	COG0302	gtp cyclohydrolase
LJA35_RS35185	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LJA35_RS35195	COG4948	Mandelate Racemase Muconate Lactonizing
LJA35_RS35205	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LJA35_RS35255	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LJA35_RS35265	COG0488	(ABC) transporter
LJA35_RS35275	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LJA35_RS35285	COG0366	Alpha amylase catalytic
LJA35_RS35285	COG1470	cell adhesion involved in biofilm formation
LJA35_RS35290	COG1609	Transcriptional regulator
LJA35_RS35295	COG2186	Transcriptional regulator
LJA35_RS35300	COG4948	Mandelate Racemase Muconate Lactonizing
LJA35_RS35305	COG1028	Short-chain dehydrogenase reductase Sdr
LJA35_RS35315	COG3618	amidohydrolase
LJA35_RS35325	COG0154	amidase activity
LJA35_RS35345	COG1621	beta-fructofuranosidase activity
LJA35_RS35355	COG1175	transmembrane transport
LJA35_RS35360	COG0395	ABC-type sugar transport system, permease component
LJA35_RS35370	COG1609	Transcriptional regulator
LJA35_RS35425	COG2205	protein histidine kinase activity
LJA35_RS35430	COG0745	RESPONSE REGULATOR receiver
LJA35_RS35440	COG1131	(ABC) transporter
LJA35_RS35445	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LJA35_RS35475	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
LJA35_RS35490	COG0583	DNA-binding transcription factor activity
LJA35_RS35510	COG0456	acetyltransferase
LJA35_RS35515	COG1733	regulation of RNA biosynthetic process
LJA35_RS35525	COG3153	acetyltransferase
LJA35_RS35525	COG0456	acetyltransferase
LJA35_RS35550	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
LJA35_RS35565	COG2197	response regulator
LJA35_RS35595	COG1846	Transcriptional regulator
LJA35_RS35645	COG1733	regulation of RNA biosynthetic process
LJA35_RS35665	COG0235	Class ii aldolase
LJA35_RS35670	COG3395	kinase activity
LJA35_RS35675	COG0473	3-isopropylmalate dehydrogenase activity
LJA35_RS35695	COG2851	Citrate transporter
LJA35_RS35700	COG1012	belongs to the aldehyde dehydrogenase family
LJA35_RS35720	COG0667	Aldo Keto reductase
LJA35_RS35725	COG1733	regulation of RNA biosynthetic process
LJA35_RS35735	COG4946	Tricorn protease homolog
LJA35_RS35735	COG1506	peptidase
LJA35_RS35735	COG0823	Involved in the tonB-independent uptake of proteins
LJA35_RS35775	COG2226	methyltransferase
LJA35_RS35780	COG2226	methyltransferase
LJA35_RS35785	COG1028	Short-chain dehydrogenase reductase Sdr
LJA35_RS35790	COG1309	transcriptional regulator
LJA35_RS35845	COG0702	epimerase
LJA35_RS35860	COG1595	DNA-templated transcription, initiation
LJA35_RS35875	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
LJA35_RS35915	COG1309	transcriptional regulator
LJA35_RS35920	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LJA35_RS35925	COG3507	Belongs to the glycosyl hydrolase 43 family
LJA35_RS35935	COG0726	polysaccharide deacetylase
LJA35_RS35955	COG1028	Short-chain dehydrogenase reductase Sdr
LJA35_RS35970	COG2318	DinB family
LJA35_RS36000	COG2197	response regulator
LJA35_RS36020	COG1595	DNA-templated transcription, initiation
LJA35_RS36095	COG1028	Short-chain dehydrogenase reductase Sdr
LJA35_RS36115	COG0583	DNA-binding transcription factor activity
LJA35_RS36125	COG1231	oxidoreductase activity
LJA35_RS36130	COG0477	Major facilitator Superfamily
LJA35_RS36195	COG2226	methyltransferase
LJA35_RS36215	COG3387	PFAM Glycoside hydrolase 15-related
LJA35_RS36235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LJA35_RS36240	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LJA35_RS36245	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LJA35_RS36265	COG2814	Major facilitator Superfamily
LJA35_RS36325	COG1309	transcriptional regulator