locus-tag	class	description
IAG44_RS00020	COG0513	Belongs to the DEAD box helicase family
IAG44_RS00025	COG2249	NAD(P)H dehydrogenase (quinone) activity
IAG44_RS00060	COG0604	alcohol dehydrogenase
IAG44_RS00060	COG3321	synthase
IAG44_RS00065	COG3321	synthase
IAG44_RS00065	COG0604	alcohol dehydrogenase
IAG44_RS00070	COG2197	response regulator
IAG44_RS00115	COG2124	cytochrome p450
IAG44_RS00120	COG2124	cytochrome p450
IAG44_RS00125	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IAG44_RS00160	COG0800	Aldolase
IAG44_RS00165	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IAG44_RS00195	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IAG44_RS00205	COG1175	transmembrane transport
IAG44_RS00210	COG1653	transport
IAG44_RS00220	COG1472	Belongs to the glycosyl hydrolase 3 family
IAG44_RS00235	COG3693	PFAM glycoside hydrolase, family 10
IAG44_RS00240	COG0531	amino acid
IAG44_RS00260	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IAG44_RS00265	COG1309	transcriptional regulator
IAG44_RS00275	COG1231	oxidoreductase activity
IAG44_RS00280	COG2409	Drug exporters of the RND superfamily
IAG44_RS00300	COG0134	indole-3-glycerol-phosphate synthase activity
IAG44_RS00310	COG2755	lipolytic protein G-D-S-L family
IAG44_RS00325	COG1609	Transcriptional regulator
IAG44_RS00325	COG2207	Transcriptional regulator
IAG44_RS00330	COG2409	Drug exporters of the RND superfamily
IAG44_RS00335	COG2197	response regulator
IAG44_RS00340	COG4585	Histidine kinase
IAG44_RS00350	COG0745	RESPONSE REGULATOR receiver
IAG44_RS00375	COG1116	anion transmembrane transporter activity
IAG44_RS00380	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IAG44_RS00385	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IAG44_RS00410	COG2223	nitrite transmembrane transporter activity
IAG44_RS00415	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IAG44_RS00450	COG2205	protein histidine kinase activity
IAG44_RS00455	COG0745	RESPONSE REGULATOR receiver
IAG44_RS00505	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IAG44_RS00525	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IAG44_RS00525	COG3608	succinylglutamate desuccinylase aspartoacylase
IAG44_RS00530	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IAG44_RS00535	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
IAG44_RS00540	COG2080	2 iron, 2 sulfur cluster binding
IAG44_RS00575	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
IAG44_RS00610	COG0367	asparagine synthase
IAG44_RS00615	COG1280	lysine exporter protein (LysE YggA)
IAG44_RS00625	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IAG44_RS00635	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
IAG44_RS00640	COG1794	racemase activity, acting on amino acids and derivatives
IAG44_RS00655	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IAG44_RS00680	COG0659	secondary active sulfate transmembrane transporter activity
IAG44_RS00685	COG2824	Alkylphosphonate utilization operon protein PhnA
IAG44_RS00725	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IAG44_RS00745	COG0367	asparagine synthase
IAG44_RS00780	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IAG44_RS00795	COG4310	Domain of unknown function (DUF2172)
IAG44_RS00805	COG0463	Glycosyl transferase, family 2
IAG44_RS00815	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
IAG44_RS00820	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IAG44_RS00830	COG2319	Wd-40 repeat
IAG44_RS00830	COG4249	Peptidase C14 caspase catalytic subunit p20
IAG44_RS00845	COG0395	ABC-type sugar transport system, permease component
IAG44_RS00850	COG1175	transmembrane transport
IAG44_RS00875	COG1028	Short-chain dehydrogenase reductase Sdr
IAG44_RS00885	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
IAG44_RS00905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IAG44_RS00905	COG3321	synthase
IAG44_RS00935	COG3547	Transposase (IS116 IS110 IS902 family)
IAG44_RS00990	COG1733	regulation of RNA biosynthetic process
IAG44_RS00995	COG2226	methyltransferase
IAG44_RS01005	COG1309	transcriptional regulator
IAG44_RS01020	COG1733	regulation of RNA biosynthetic process
IAG44_RS01065	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IAG44_RS01075	COG0477	Major facilitator Superfamily
IAG44_RS01080	COG1028	Short-chain dehydrogenase reductase Sdr
IAG44_RS01105	COG0386	Belongs to the glutathione peroxidase family
IAG44_RS01110	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IAG44_RS01115	COG2192	nodulation
IAG44_RS01150	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IAG44_RS01160	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IAG44_RS01190	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IAG44_RS01200	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IAG44_RS01205	COG1028	Short-chain dehydrogenase reductase Sdr
IAG44_RS01210	COG2062	phosphohistidine phosphatase, SixA
IAG44_RS01215	COG1162	GTPase activity
IAG44_RS01270	COG4101	3-hydroxyanthranilate 3,4-dioxygenase activity
IAG44_RS01285	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IAG44_RS01290	COG4569	acetaldehyde dehydrogenase (acetylating) activity
IAG44_RS01295	COG3971	2-oxopent-4-enoate hydratase activity
IAG44_RS01305	COG1113	amino acid transport
IAG44_RS01310	COG3844	kynureninase activity
IAG44_RS01340	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IAG44_RS01355	COG1595	DNA-templated transcription, initiation
IAG44_RS01375	COG0569	domain protein
IAG44_RS01380	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IAG44_RS01385	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IAG44_RS01390	COG2268	Band 7 protein
IAG44_RS01395	COG1585	Membrane protein implicated in regulation of membrane protease activity
IAG44_RS01400	COG0309	Hydrogenase expression formation protein (HypE)
IAG44_RS01405	COG0409	Hydrogenase expression formation protein
IAG44_RS01435	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
IAG44_RS01445	COG1131	(ABC) transporter
IAG44_RS01475	COG0589	response to stress
IAG44_RS01515	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
IAG44_RS01520	COG0674	pyruvate-flavodoxin oxidoreductase activity
IAG44_RS01525	COG1013	pyruvate-flavodoxin oxidoreductase activity
IAG44_RS01540	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
IAG44_RS01545	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
IAG44_RS01555	COG1012	belongs to the aldehyde dehydrogenase family
IAG44_RS01575	COG0517	IMP dehydrogenase activity
IAG44_RS01575	COG0516	GMP reductase activity
IAG44_RS01600	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
IAG44_RS01605	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IAG44_RS01620	COG0716	FMN binding
IAG44_RS01675	COG0589	response to stress
IAG44_RS01680	COG0516	GMP reductase activity
IAG44_RS01680	COG0517	IMP dehydrogenase activity
IAG44_RS01690	COG0574	Belongs to the PEP-utilizing enzyme family
IAG44_RS01690	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IAG44_RS01705	COG1140	nitrate reductase beta subunit
IAG44_RS01710	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
IAG44_RS01745	COG1172	Belongs to the binding-protein-dependent transport system permease family
IAG44_RS01750	COG4211	Belongs to the binding-protein-dependent transport system permease family
IAG44_RS01755	COG1129	ABC transporter
IAG44_RS01775	COG2124	cytochrome p450
IAG44_RS01780	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IAG44_RS01790	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IAG44_RS01795	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IAG44_RS01810	COG0318	PFAM AMP-dependent synthetase and ligase
IAG44_RS01815	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IAG44_RS01885	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IAG44_RS01890	COG4948	Mandelate Racemase Muconate Lactonizing
IAG44_RS01910	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IAG44_RS01935	COG0438	transferase activity, transferring glycosyl groups
IAG44_RS01945	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IAG44_RS01950	COG2144	transferase activity, transferring acyl groups
IAG44_RS01970	COG2072	flavoprotein involved in K transport
IAG44_RS01980	COG1741	Belongs to the pirin family
IAG44_RS01985	COG1733	regulation of RNA biosynthetic process
IAG44_RS02010	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IAG44_RS02010	COG2070	2-Nitropropane dioxygenase
IAG44_RS02015	COG0300	oxidoreductase activity
IAG44_RS02015	COG3321	synthase
IAG44_RS02015	COG1028	Short-chain dehydrogenase reductase Sdr
IAG44_RS02015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IAG44_RS02015	COG0318	PFAM AMP-dependent synthetase and ligase
IAG44_RS02030	COG3971	2-oxopent-4-enoate hydratase activity
IAG44_RS02035	COG4569	acetaldehyde dehydrogenase (acetylating) activity
IAG44_RS02040	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IAG44_RS02060	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IAG44_RS02090	COG0346	lactoylglutathione lyase activity
IAG44_RS02100	COG0656	L-ascorbic acid biosynthetic process
IAG44_RS02105	COG1760	l-serine dehydratase
IAG44_RS02125	COG0406	alpha-ribazole phosphatase activity
IAG44_RS02190	COG0475	glutathione-regulated potassium exporter activity
IAG44_RS02200	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IAG44_RS02210	COG0546	phosphoglycolate phosphatase activity
IAG44_RS02245	COG2226	methyltransferase
IAG44_RS02275	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IAG44_RS02290	COG2203	Gaf domain
IAG44_RS02290	COG2199	diguanylate cyclase activity
IAG44_RS02330	COG2124	cytochrome p450
IAG44_RS02340	COG0009	L-threonylcarbamoyladenylate synthase
IAG44_RS02365	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAG44_RS02390	COG2207	Transcriptional regulator
IAG44_RS02395	COG2223	nitrite transmembrane transporter activity
IAG44_RS02420	COG0745	RESPONSE REGULATOR receiver
IAG44_RS02440	COG0181	hydroxymethylbilane synthase activity
IAG44_RS02445	COG3547	Transposase (IS116 IS110 IS902 family)
IAG44_RS02455	COG0842	Transport permease protein
IAG44_RS02505	COG0477	Major facilitator Superfamily
IAG44_RS02585	COG2340	Cysteine-rich secretory protein family
IAG44_RS02590	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IAG44_RS02590	COG0515	serine threonine protein kinase
IAG44_RS02600	COG0667	Aldo Keto reductase
IAG44_RS02615	COG2814	Major facilitator Superfamily
IAG44_RS02625	COG0328	RNA-DNA hybrid ribonuclease activity
IAG44_RS02630	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IAG44_RS02640	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IAG44_RS02650	COG0596	Alpha beta hydrolase
IAG44_RS02655	COG0740	serine-type endopeptidase activity
IAG44_RS02660	COG0740	serine-type endopeptidase activity
IAG44_RS02665	COG1396	sequence-specific DNA binding
IAG44_RS02670	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IAG44_RS02675	COG1191	sigma factor activity
IAG44_RS02705	COG0667	Aldo Keto reductase
IAG44_RS02710	COG0583	DNA-binding transcription factor activity
IAG44_RS02720	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IAG44_RS02725	COG0346	lactoylglutathione lyase activity
IAG44_RS02735	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IAG44_RS02740	COG0667	Aldo Keto reductase
IAG44_RS02745	COG1012	belongs to the aldehyde dehydrogenase family
IAG44_RS02765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAG44_RS02800	COG0673	inositol 2-dehydrogenase activity
IAG44_RS02815	COG0510	thiamine kinase activity
IAG44_RS02850	COG1024	Enoyl-CoA hydratase
IAG44_RS02865	COG2267	carboxylic ester hydrolase activity
IAG44_RS02875	COG0318	PFAM AMP-dependent synthetase and ligase
IAG44_RS02890	COG2366	antibiotic biosynthetic process
IAG44_RS02900	COG2070	2-Nitropropane dioxygenase
IAG44_RS02915	COG0515	serine threonine protein kinase
IAG44_RS02940	COG0402	S-adenosylhomocysteine deaminase activity
IAG44_RS02945	COG2197	response regulator
IAG44_RS02955	COG1063	alcohol dehydrogenase
IAG44_RS02960	COG1028	Short-chain dehydrogenase reductase Sdr
IAG44_RS02965	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IAG44_RS02970	COG0583	DNA-binding transcription factor activity
IAG44_RS02995	COG1960	acyl-CoA dehydrogenase activity
IAG44_RS03015	COG2326	polyphosphate kinase activity
IAG44_RS03020	COG0318	PFAM AMP-dependent synthetase and ligase
IAG44_RS03025	COG1309	transcriptional regulator
IAG44_RS03070	COG1960	acyl-CoA dehydrogenase activity
IAG44_RS03075	COG1960	acyl-CoA dehydrogenase activity
IAG44_RS03080	COG1028	Short-chain dehydrogenase reductase Sdr
IAG44_RS03095	COG1082	Xylose isomerase domain protein TIM barrel
IAG44_RS03095	COG3185	4-Hydroxyphenylpyruvate dioxygenase
IAG44_RS03100	COG1063	alcohol dehydrogenase
IAG44_RS03140	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IAG44_RS03165	COG2175	clavaminate synthase activity
IAG44_RS03170	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IAG44_RS03190	COG1404	Belongs to the peptidase S8 family
IAG44_RS03195	COG2376	Dihydroxyacetone kinase
IAG44_RS03200	COG1461	Dihydroxyacetone kinase
IAG44_RS03205	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
IAG44_RS03225	COG0446	pyridine nucleotide-disulphide oxidoreductase
IAG44_RS03225	COG1902	pentaerythritol trinitrate reductase activity
IAG44_RS03240	COG1609	Transcriptional regulator
IAG44_RS03275	COG0765	amino acid transport
IAG44_RS03280	COG0765	amino acid transport
IAG44_RS03285	COG1126	abc transporter atp-binding protein
IAG44_RS03300	COG1917	Cupin 2, conserved barrel domain protein
IAG44_RS03345	COG0148	phosphopyruvate hydratase activity
IAG44_RS03355	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IAG44_RS03450	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IAG44_RS03460	COG1024	Enoyl-CoA hydratase
IAG44_RS03470	COG3963	phosphatidate phosphatase activity
IAG44_RS03480	COG2197	response regulator
IAG44_RS03485	COG3250	beta-galactosidase activity
IAG44_RS03495	COG1609	Transcriptional regulator
IAG44_RS03515	COG1028	Short-chain dehydrogenase reductase Sdr
IAG44_RS03535	COG2986	histidine ammonia-lyase
IAG44_RS03545	COG1414	Transcriptional regulator
IAG44_RS03575	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IAG44_RS03580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IAG44_RS03605	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IAG44_RS03625	COG1595	DNA-templated transcription, initiation
IAG44_RS03645	COG3507	Belongs to the glycosyl hydrolase 43 family
IAG44_RS03690	COG2319	Wd-40 repeat
IAG44_RS03690	COG4249	Peptidase C14 caspase catalytic subunit p20
IAG44_RS03695	COG2186	Transcriptional regulator
IAG44_RS03705	COG0745	RESPONSE REGULATOR receiver
IAG44_RS03710	COG2205	protein histidine kinase activity
IAG44_RS03720	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IAG44_RS03730	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
IAG44_RS03740	COG0515	serine threonine protein kinase
IAG44_RS03740	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IAG44_RS03745	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IAG44_RS03745	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IAG44_RS03750	COG0655	NAD(P)H dehydrogenase (quinone) activity
IAG44_RS03755	COG2226	methyltransferase
IAG44_RS03760	COG2814	Major facilitator Superfamily
IAG44_RS03780	COG2807	transmembrane transport
IAG44_RS03800	COG1414	Transcriptional regulator
IAG44_RS03830	COG3851	Histidine kinase
IAG44_RS03885	COG1028	Short-chain dehydrogenase reductase Sdr
IAG44_RS03940	COG2192	nodulation
IAG44_RS03970	COG0505	Belongs to the CarA family
IAG44_RS03975	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IAG44_RS03980	COG1280	lysine exporter protein (LysE YggA)
IAG44_RS04000	COG0076	glutamate decarboxylase activity
IAG44_RS04010	COG2124	cytochrome p450
IAG44_RS04015	COG0537	adenosine 5'-monophosphoramidase activity
IAG44_RS04020	COG1404	Belongs to the peptidase S8 family
IAG44_RS04045	COG2837	iron assimilation
IAG44_RS04065	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IAG44_RS04080	COG1309	transcriptional regulator
IAG44_RS04085	COG0726	polysaccharide deacetylase
IAG44_RS04110	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IAG44_RS04130	COG1309	transcriptional regulator
IAG44_RS04155	COG2226	methyltransferase
IAG44_RS04160	COG0640	Transcriptional regulator
IAG44_RS04170	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IAG44_RS04210	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IAG44_RS04230	COG0583	DNA-binding transcription factor activity
IAG44_RS04240	COG1132	(ABC) transporter
IAG44_RS04250	COG1132	(ABC) transporter
IAG44_RS04255	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
IAG44_RS04260	COG1120	ATPase activity
IAG44_RS04265	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAG44_RS04270	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAG44_RS04275	COG3486	L-lysine 6-monooxygenase (NADPH) activity
IAG44_RS04310	COG1609	Transcriptional regulator
IAG44_RS04320	COG1175	transmembrane transport
IAG44_RS04330	COG3250	beta-galactosidase activity
IAG44_RS04335	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IAG44_RS04340	COG1072	(Pantothenic acid kinase))
IAG44_RS04355	COG0745	RESPONSE REGULATOR receiver
IAG44_RS04370	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IAG44_RS04385	COG3458	cephalosporin-C deacetylase activity
IAG44_RS04390	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IAG44_RS04405	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IAG44_RS04410	COG2267	carboxylic ester hydrolase activity
IAG44_RS04420	COG5650	phosphatidylinositol metabolic process
IAG44_RS04445	COG1113	amino acid transport
IAG44_RS04450	COG2186	Transcriptional regulator
IAG44_RS04455	COG1968	undecaprenyl-diphosphatase activity
IAG44_RS04460	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IAG44_RS04465	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IAG44_RS04475	COG0640	Transcriptional regulator
IAG44_RS04480	COG0346	lactoylglutathione lyase activity
IAG44_RS04500	COG1175	transmembrane transport
IAG44_RS04505	COG0395	ABC-type sugar transport system, permease component
IAG44_RS04525	COG0675	Transposase, IS605 OrfB family
IAG44_RS04535	COG0586	Pfam SNARE associated Golgi protein
IAG44_RS04540	COG4585	Histidine kinase
IAG44_RS04545	COG2197	response regulator
IAG44_RS04555	COG1414	Transcriptional regulator
IAG44_RS04595	COG1051	belongs to the nudix hydrolase family
IAG44_RS04605	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAG44_RS04615	COG0726	polysaccharide deacetylase
IAG44_RS04640	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IAG44_RS04730	COG4221	oxidoreductase activity
IAG44_RS04760	COG1846	Transcriptional regulator
IAG44_RS04790	COG1733	regulation of RNA biosynthetic process
IAG44_RS04805	COG1022	Amp-dependent synthetase and ligase
IAG44_RS04805	COG3320	Male sterility
IAG44_RS04860	COG1028	Short-chain dehydrogenase reductase Sdr
IAG44_RS04870	COG1454	alcohol dehydrogenase
IAG44_RS04870	COG1012	belongs to the aldehyde dehydrogenase family
IAG44_RS04875	COG0318	PFAM AMP-dependent synthetase and ligase
IAG44_RS04895	COG3321	synthase
IAG44_RS04895	COG0604	alcohol dehydrogenase
IAG44_RS04895	COG1028	Short-chain dehydrogenase reductase Sdr
IAG44_RS04900	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IAG44_RS04905	COG2409	Drug exporters of the RND superfamily
IAG44_RS04925	COG0159	tryptophan synthase activity
IAG44_RS04935	COG0189	ligase activity
IAG44_RS04955	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IAG44_RS04980	COG0297	glycogen (starch) synthase activity
IAG44_RS05040	COG1215	transferase activity, transferring glycosyl groups
IAG44_RS05080	COG1349	DNA-binding transcription factor activity
IAG44_RS05130	COG1735	metal-dependent hydrolase with the TIM-barrel fold
IAG44_RS05135	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
IAG44_RS05140	COG1309	transcriptional regulator
IAG44_RS05145	COG1028	Short-chain dehydrogenase reductase Sdr
IAG44_RS05150	COG1940	carbohydrate kinase activity
IAG44_RS05160	COG2813	Specifically methylates the guanine in position
IAG44_RS05170	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IAG44_RS05190	COG0326	Molecular chaperone. Has ATPase activity
IAG44_RS05220	COG0445	tRNA wobble uridine modification
IAG44_RS05235	COG1660	Displays ATPase and GTPase activities
IAG44_RS05275	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
IAG44_RS05300	COG0204	Acyl-transferase
IAG44_RS05335	COG0584	glycerophosphoryl diester phosphodiesterase
IAG44_RS05370	COG0671	phosphoesterase, PA-phosphatase related
IAG44_RS05380	COG1309	transcriptional regulator
IAG44_RS05410	COG3509	depolymerase
IAG44_RS05430	COG1960	acyl-CoA dehydrogenase activity
IAG44_RS05445	COG3629	intracellular signal transduction
IAG44_RS05455	COG1012	belongs to the aldehyde dehydrogenase family
IAG44_RS05490	COG3239	Fatty acid desaturase
IAG44_RS05495	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IAG44_RS05500	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IAG44_RS05505	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IAG44_RS05545	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IAG44_RS05560	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
IAG44_RS05595	COG1278	Cold shock
IAG44_RS05630	COG4585	Histidine kinase
IAG44_RS05635	COG2409	Drug exporters of the RND superfamily
IAG44_RS05650	COG1063	alcohol dehydrogenase
IAG44_RS05655	COG0179	Fumarylacetoacetate (FAA) hydrolase
IAG44_RS05665	COG0129	dihydroxy-acid dehydratase activity
IAG44_RS05670	COG1309	transcriptional regulator
IAG44_RS05675	COG1309	transcriptional regulator
IAG44_RS05680	COG2409	Drug exporters of the RND superfamily
IAG44_RS05705	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IAG44_RS05705	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IAG44_RS05705	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IAG44_RS05710	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
IAG44_RS05710	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IAG44_RS05710	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IAG44_RS05725	COG1404	Belongs to the peptidase S8 family
IAG44_RS05740	COG0477	Major facilitator Superfamily
IAG44_RS05750	COG3321	synthase
IAG44_RS05750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IAG44_RS05760	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IAG44_RS05765	COG0596	Alpha beta hydrolase
IAG44_RS05790	COG0673	inositol 2-dehydrogenase activity
IAG44_RS05805	COG1028	Short-chain dehydrogenase reductase Sdr
IAG44_RS05810	COG0673	inositol 2-dehydrogenase activity
IAG44_RS05820	COG0477	Major facilitator Superfamily
IAG44_RS05850	COG2188	Transcriptional regulator
IAG44_RS05860	COG1960	acyl-CoA dehydrogenase activity
IAG44_RS05870	COG2610	gluconate transmembrane transporter activity
IAG44_RS05875	COG4948	Mandelate Racemase Muconate Lactonizing
IAG44_RS05985	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IAG44_RS05995	COG2267	carboxylic ester hydrolase activity
IAG44_RS06000	COG4585	Histidine kinase
IAG44_RS06010	COG1136	(ABC) transporter
IAG44_RS06015	COG2197	response regulator
IAG44_RS06020	COG0561	phosphatase activity
IAG44_RS06025	COG0174	glutamine synthetase
IAG44_RS06045	COG1132	(ABC) transporter
IAG44_RS06060	COG3959	Transketolase, thiamine diphosphate binding domain
IAG44_RS06065	COG3958	Transketolase
IAG44_RS06080	COG0583	DNA-binding transcription factor activity
IAG44_RS06090	COG1063	alcohol dehydrogenase
IAG44_RS06125	COG2968	Membrane
IAG44_RS06130	COG2755	lipolytic protein G-D-S-L family
IAG44_RS06180	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IAG44_RS06185	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IAG44_RS06210	COG1233	COG1233 Phytoene dehydrogenase and related
IAG44_RS06220	COG1562	ergosterol biosynthetic process
IAG44_RS06225	COG1134	teichoic acid transport
IAG44_RS06265	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
IAG44_RS06275	COG1024	Enoyl-CoA hydratase
IAG44_RS06280	COG2183	response to ionizing radiation
IAG44_RS06285	COG0488	(ABC) transporter
IAG44_RS06295	COG2936	dipeptidyl-peptidase activity
IAG44_RS06300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IAG44_RS06310	COG1113	amino acid transport
IAG44_RS06315	COG1024	Enoyl-CoA hydratase
IAG44_RS06315	COG1250	3-hydroxyacyl-CoA dehydrogenase
IAG44_RS06320	COG0183	Belongs to the thiolase family
IAG44_RS06325	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IAG44_RS06330	COG3268	Saccharopine dehydrogenase
IAG44_RS06340	COG1515	deoxyribonuclease V activity
IAG44_RS06355	COG0488	(ABC) transporter
IAG44_RS06360	COG1834	amidinotransferase
IAG44_RS06410	COG1793	dna ligase
IAG44_RS06420	COG1846	Transcriptional regulator
IAG44_RS06435	COG0183	Belongs to the thiolase family
IAG44_RS06440	COG3485	protocatechuate 3,4-dioxygenase
IAG44_RS06445	COG3485	protocatechuate 3,4-dioxygenase
IAG44_RS06450	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IAG44_RS06455	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IAG44_RS06490	COG3511	phospholipase C
IAG44_RS06580	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IAG44_RS06600	COG1486	melibiose metabolic process
IAG44_RS06610	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IAG44_RS06620	COG1175	transmembrane transport
IAG44_RS06630	COG3250	beta-galactosidase activity
IAG44_RS06635	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IAG44_RS06665	COG1028	Short-chain dehydrogenase reductase Sdr
IAG44_RS06690	COG0596	Alpha beta hydrolase
IAG44_RS06705	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IAG44_RS06720	COG0166	Belongs to the GPI family
IAG44_RS06725	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
IAG44_RS06730	COG0406	alpha-ribazole phosphatase activity
IAG44_RS06740	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IAG44_RS06750	COG0477	Major facilitator Superfamily
IAG44_RS06790	COG3467	pyridoxamine 5'-phosphate
IAG44_RS06815	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IAG44_RS06830	COG0297	glycogen (starch) synthase activity
IAG44_RS06855	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAG44_RS06865	COG0456	acetyltransferase
IAG44_RS06865	COG1214	PFAM Peptidase M22, glycoprotease
IAG44_RS06885	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IAG44_RS06895	COG1725	Transcriptional regulator
IAG44_RS06900	COG1131	(ABC) transporter
IAG44_RS06935	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IAG44_RS06940	COG3938	Belongs to the proline racemase family
IAG44_RS07000	COG0395	ABC-type sugar transport system, permease component
IAG44_RS07005	COG1175	transmembrane transport
IAG44_RS07025	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IAG44_RS07035	COG2223	nitrite transmembrane transporter activity
IAG44_RS07090	COG0673	inositol 2-dehydrogenase activity
IAG44_RS07100	COG1172	Belongs to the binding-protein-dependent transport system permease family
IAG44_RS07105	COG1129	ABC transporter
IAG44_RS07110	COG1940	carbohydrate kinase activity
IAG44_RS07125	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IAG44_RS07135	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IAG44_RS07160	COG1028	Short-chain dehydrogenase reductase Sdr
IAG44_RS07170	COG5297	Belongs to the glycosyl hydrolase family 6
IAG44_RS07175	COG4733	cellulase activity
IAG44_RS07175	COG5297	Belongs to the glycosyl hydrolase family 6
IAG44_RS07200	COG4106	trans-aconitate 2-methyltransferase activity
IAG44_RS07200	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IAG44_RS07205	COG2154	pterin-4-alpha-carbinolamine dehydratase
IAG44_RS07235	COG0443	Heat shock 70 kDa protein
IAG44_RS07265	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
IAG44_RS07295	COG1191	sigma factor activity
IAG44_RS07300	COG0488	(ABC) transporter
IAG44_RS07320	COG1619	proteins homologs of microcin C7 resistance protein MccF
IAG44_RS07330	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IAG44_RS07355	COG2208	phosphoserine phosphatase activity
IAG44_RS07355	COG1366	Belongs to the anti-sigma-factor antagonist family
IAG44_RS07355	COG2172	sigma factor antagonist activity
IAG44_RS07395	COG1250	3-hydroxyacyl-CoA dehydrogenase
IAG44_RS07410	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IAG44_RS07410	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IAG44_RS07425	COG1960	acyl-CoA dehydrogenase activity
IAG44_RS07430	COG0688	phosphatidylethanolamine metabolic process
IAG44_RS07440	COG1929	Belongs to the glycerate kinase type-1 family
IAG44_RS07445	COG0494	nUDIX hydrolase
IAG44_RS07455	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IAG44_RS07480	COG0640	Transcriptional regulator
IAG44_RS07495	COG0156	8-amino-7-oxononanoate synthase activity
IAG44_RS07510	COG0243	molybdopterin cofactor binding
IAG44_RS07560	COG1082	Xylose isomerase domain protein TIM barrel
IAG44_RS07565	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IAG44_RS07575	COG0483	inositol monophosphate 1-phosphatase activity
IAG44_RS07595	COG3851	Histidine kinase
IAG44_RS07610	COG1953	Uracil, thiamine, allantoin
IAG44_RS07620	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IAG44_RS07635	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IAG44_RS07660	COG0405	Gamma-glutamyltransferase
IAG44_RS07685	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
IAG44_RS07690	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IAG44_RS07695	COG0745	RESPONSE REGULATOR receiver
IAG44_RS07700	COG1028	Short-chain dehydrogenase reductase Sdr
IAG44_RS07700	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IAG44_RS07700	COG0318	PFAM AMP-dependent synthetase and ligase
IAG44_RS07700	COG3321	synthase
IAG44_RS07700	COG0300	oxidoreductase activity
IAG44_RS07715	COG0077	Prephenate dehydratase
IAG44_RS07720	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IAG44_RS07725	COG1733	regulation of RNA biosynthetic process
IAG44_RS07735	COG0604	alcohol dehydrogenase
IAG44_RS07750	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IAG44_RS07755	COG0477	Major facilitator Superfamily
IAG44_RS07765	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IAG44_RS07780	COG3135	benzoate transporter
IAG44_RS07790	COG0109	protoheme IX farnesyltransferase activity
IAG44_RS07795	COG2226	methyltransferase
IAG44_RS07810	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IAG44_RS07815	COG0142	geranyltranstransferase activity
IAG44_RS07830	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IAG44_RS07835	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
IAG44_RS07855	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IAG44_RS07870	COG2226	methyltransferase
IAG44_RS07880	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IAG44_RS07890	COG1940	carbohydrate kinase activity
IAG44_RS07895	COG1129	ABC transporter
IAG44_RS07910	COG2188	Transcriptional regulator
IAG44_RS07915	COG0673	inositol 2-dehydrogenase activity
IAG44_RS07925	COG2197	response regulator
IAG44_RS07945	COG4266	Belongs to the allantoicase family
IAG44_RS07950	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IAG44_RS07955	COG1414	Transcriptional regulator
IAG44_RS07975	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IAG44_RS07995	COG4264	IucA IucC family
IAG44_RS08010	COG1733	regulation of RNA biosynthetic process
IAG44_RS08035	COG2351	hydroxyisourate hydrolase activity
IAG44_RS08055	COG3622	Belongs to the hyi family
IAG44_RS08060	COG0318	PFAM AMP-dependent synthetase and ligase
IAG44_RS08065	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IAG44_RS08070	COG2197	response regulator
IAG44_RS08075	COG4133	protoheme IX ABC transporter activity
IAG44_RS08090	COG0598	Magnesium transport protein CorA
IAG44_RS08100	COG2409	Drug exporters of the RND superfamily
IAG44_RS08105	COG4585	Histidine kinase
IAG44_RS08110	COG2197	response regulator
IAG44_RS08135	COG5634	Uncharacterized conserved protein (DUF2278)
IAG44_RS08140	COG3940	Belongs to the glycosyl hydrolase 43 family
IAG44_RS08145	COG3940	Belongs to the glycosyl hydrolase 43 family
IAG44_RS08155	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IAG44_RS08155	COG3608	succinylglutamate desuccinylase aspartoacylase
IAG44_RS08160	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IAG44_RS08175	COG3835	regulator
IAG44_RS08185	COG1802	Transcriptional regulator
IAG44_RS08235	COG1162	GTPase activity
IAG44_RS08245	COG0745	RESPONSE REGULATOR receiver
IAG44_RS08270	COG0277	FAD linked oxidase domain protein
IAG44_RS08285	COG1175	transmembrane transport
IAG44_RS08290	COG0395	ABC-type sugar transport system, permease component
IAG44_RS08300	COG4555	ABC transporter
IAG44_RS08395	COG0531	amino acid
IAG44_RS08400	COG2040	homocysteine
IAG44_RS08430	COG0395	ABC-type sugar transport system, permease component
IAG44_RS08435	COG1175	transmembrane transport
IAG44_RS08445	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IAG44_RS08465	COG0395	ABC-type sugar transport system, permease component
IAG44_RS08475	COG0596	Alpha beta hydrolase
IAG44_RS08515	COG4977	sequence-specific DNA binding
IAG44_RS08515	COG1917	Cupin 2, conserved barrel domain protein
IAG44_RS08520	COG0702	epimerase
IAG44_RS08530	COG1960	acyl-CoA dehydrogenase activity
IAG44_RS08535	COG3284	Transcriptional regulator
IAG44_RS08550	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IAG44_RS08560	COG0175	sulfate reduction
IAG44_RS08565	COG0529	Catalyzes the synthesis of activated sulfate
IAG44_RS08590	COG1116	anion transmembrane transporter activity
IAG44_RS08595	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IAG44_RS08610	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IAG44_RS08615	COG0667	Aldo Keto reductase
IAG44_RS08630	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IAG44_RS08645	COG1175	transmembrane transport
IAG44_RS08685	COG1716	ATPase activity
IAG44_RS08695	COG3173	Aminoglycoside phosphotransferase
IAG44_RS08710	COG0583	DNA-binding transcription factor activity
IAG44_RS08740	COG1309	transcriptional regulator
IAG44_RS08755	COG1404	Belongs to the peptidase S8 family
IAG44_RS08780	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IAG44_RS08795	COG0640	Transcriptional regulator
IAG44_RS08805	COG2986	histidine ammonia-lyase
IAG44_RS08815	COG5002	protein histidine kinase activity
IAG44_RS08820	COG2018	Roadblock/LC7 domain
IAG44_RS08845	COG1174	glycine betaine transport
IAG44_RS08870	COG0745	RESPONSE REGULATOR receiver
IAG44_RS08875	COG2205	protein histidine kinase activity
IAG44_RS08885	COG2271	Major facilitator Superfamily
IAG44_RS08890	COG0800	Aldolase
IAG44_RS08895	COG1349	DNA-binding transcription factor activity
IAG44_RS08915	COG3903	Transcriptional regulator
IAG44_RS08915	COG3629	intracellular signal transduction
IAG44_RS08920	COG3629	intracellular signal transduction
IAG44_RS08920	COG3903	Transcriptional regulator
IAG44_RS08930	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IAG44_RS08935	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IAG44_RS08980	COG4152	abc transporter atp-binding protein
IAG44_RS08995	COG3220	belongs to the UPF0276 family
IAG44_RS09015	COG3253	May function as heme-dependent peroxidase
IAG44_RS09030	COG0446	pyridine nucleotide-disulphide oxidoreductase
IAG44_RS09045	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IAG44_RS09060	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
IAG44_RS09065	COG3833	ABC-type maltose transport systems, permease component
IAG44_RS09080	COG3250	beta-galactosidase activity
IAG44_RS09085	COG1609	Transcriptional regulator
IAG44_RS09090	COG0183	Belongs to the thiolase family
IAG44_RS09095	COG1024	Enoyl-CoA hydratase
IAG44_RS09095	COG1250	3-hydroxyacyl-CoA dehydrogenase
IAG44_RS09105	COG0531	amino acid
IAG44_RS09110	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IAG44_RS09115	COG4214	carbohydrate transport
IAG44_RS09125	COG4213	ABC transporter substrate-binding protein
IAG44_RS09130	COG1940	carbohydrate kinase activity
IAG44_RS09135	COG0395	ABC-type sugar transport system, permease component
IAG44_RS09140	COG1175	transmembrane transport
IAG44_RS09145	COG1653	transport
IAG44_RS09175	COG0395	ABC-type sugar transport system, permease component
IAG44_RS09180	COG4209	transmembrane transport
IAG44_RS09185	COG3458	cephalosporin-C deacetylase activity
IAG44_RS09200	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IAG44_RS09210	COG0702	epimerase
IAG44_RS09215	COG4257	antibiotic catabolic process
IAG44_RS09225	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IAG44_RS09285	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IAG44_RS09290	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
IAG44_RS09355	COG1401	restriction endodeoxyribonuclease activity
IAG44_RS09365	COG0210	DNA helicase
IAG44_RS09385	COG1132	(ABC) transporter
IAG44_RS09390	COG0515	serine threonine protein kinase
IAG44_RS09435	COG1024	Enoyl-CoA hydratase
IAG44_RS09445	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IAG44_RS09450	COG2235	arginine
IAG44_RS09455	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IAG44_RS09480	COG1799	cell septum assembly
IAG44_RS09515	COG0235	Class ii aldolase
IAG44_RS09515	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
IAG44_RS09535	COG0402	S-adenosylhomocysteine deaminase activity
IAG44_RS09540	COG1703	isobutyryl-CoA mutase activity
IAG44_RS09540	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IAG44_RS09540	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IAG44_RS09560	COG2197	response regulator
IAG44_RS09570	COG0318	PFAM AMP-dependent synthetase and ligase
IAG44_RS09580	COG2084	Dehydrogenase
IAG44_RS09595	COG1028	Short-chain dehydrogenase reductase Sdr
IAG44_RS09605	COG2867	negative regulation of translational initiation
IAG44_RS09610	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IAG44_RS09615	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IAG44_RS09620	COG0662	Cupin 2, conserved barrel domain protein
IAG44_RS09645	COG1028	Short-chain dehydrogenase reductase Sdr
IAG44_RS09700	COG1404	Belongs to the peptidase S8 family
IAG44_RS09720	COG0367	asparagine synthase
IAG44_RS09745	COG2345	Transcriptional regulator
IAG44_RS09750	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IAG44_RS09755	COG2226	methyltransferase
IAG44_RS09760	COG1846	Transcriptional regulator
IAG44_RS09770	COG0475	glutathione-regulated potassium exporter activity
IAG44_RS09780	COG2345	Transcriptional regulator
IAG44_RS09810	COG2409	Drug exporters of the RND superfamily
IAG44_RS09820	COG1028	Short-chain dehydrogenase reductase Sdr
IAG44_RS09825	COG0367	asparagine synthase
IAG44_RS09835	COG3104	oligopeptide transport
IAG44_RS09845	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IAG44_RS09850	COG0531	amino acid
IAG44_RS09855	COG0569	domain protein
IAG44_RS09890	COG0756	dUTP diphosphatase activity
IAG44_RS09910	COG2205	protein histidine kinase activity
IAG44_RS09915	COG0745	RESPONSE REGULATOR receiver
IAG44_RS09925	COG0483	inositol monophosphate 1-phosphatase activity
IAG44_RS09930	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
IAG44_RS09965	COG1435	thymidine kinase activity
IAG44_RS09985	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IAG44_RS09990	COG1802	Transcriptional regulator
IAG44_RS10005	COG0612	Peptidase, M16
IAG44_RS10010	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IAG44_RS10030	COG0372	Belongs to the citrate synthase family
IAG44_RS10045	COG3290	protein histidine kinase activity
IAG44_RS10050	COG4565	transcriptional regulatory protein
IAG44_RS10055	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IAG44_RS10065	COG2197	response regulator
IAG44_RS10080	COG0187	DNA topoisomerase II activity
IAG44_RS10110	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
IAG44_RS10145	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IAG44_RS10155	COG0588	phosphoglycerate mutase activity
IAG44_RS10170	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IAG44_RS10175	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IAG44_RS10180	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IAG44_RS10210	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IAG44_RS10220	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IAG44_RS10225	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IAG44_RS10235	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IAG44_RS10255	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IAG44_RS10275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAG44_RS10280	COG2197	response regulator
IAG44_RS10315	COG2205	protein histidine kinase activity
IAG44_RS10320	COG0745	RESPONSE REGULATOR receiver
IAG44_RS10325	COG1126	abc transporter atp-binding protein
IAG44_RS10330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IAG44_RS10335	COG0765	amino acid transport
IAG44_RS10340	COG0765	amino acid transport
IAG44_RS10355	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IAG44_RS10370	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IAG44_RS10375	COG0628	permease
IAG44_RS10390	COG1201	RNA secondary structure unwinding
IAG44_RS10395	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IAG44_RS10400	COG1028	Short-chain dehydrogenase reductase Sdr
IAG44_RS10405	COG0783	Belongs to the Dps family
IAG44_RS10410	COG1396	sequence-specific DNA binding
IAG44_RS10415	COG1058	Belongs to the CinA family
IAG44_RS10415	COG1546	Belongs to the CinA family
IAG44_RS10425	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IAG44_RS10435	COG1674	ftsk spoiiie
IAG44_RS10450	COG2770	Histidine kinase
IAG44_RS10450	COG2208	phosphoserine phosphatase activity
IAG44_RS10480	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IAG44_RS10485	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IAG44_RS10500	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
IAG44_RS10505	COG0612	Peptidase, M16
IAG44_RS10510	COG1185	polyribonucleotide nucleotidyltransferase activity
IAG44_RS10515	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IAG44_RS10530	COG1674	ftsk spoiiie
IAG44_RS10585	COG0455	bacterial-type flagellum organization
IAG44_RS10600	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IAG44_RS10605	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IAG44_RS10615	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IAG44_RS10630	COG0779	Required for maturation of 30S ribosomal subunits
IAG44_RS10650	COG0442	prolyl-tRNA aminoacylation
IAG44_RS10665	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IAG44_RS10670	COG0750	zinc metalloprotease
IAG44_RS10675	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
IAG44_RS10700	COG1605	Chorismate mutase
IAG44_RS10725	COG0395	ABC-type sugar transport system, permease component
IAG44_RS10730	COG4209	transmembrane transport
IAG44_RS10735	COG1653	transport
IAG44_RS10740	COG1472	Belongs to the glycosyl hydrolase 3 family
IAG44_RS10750	COG1012	belongs to the aldehyde dehydrogenase family
IAG44_RS10775	COG2508	Transcriptional regulator
IAG44_RS10785	COG1177	transmembrane transport
IAG44_RS10795	COG3842	ATPase activity
IAG44_RS10820	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IAG44_RS10825	COG0584	glycerophosphoryl diester phosphodiesterase
IAG44_RS10865	COG1012	belongs to the aldehyde dehydrogenase family
IAG44_RS10875	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IAG44_RS10910	COG3842	ATPase activity
IAG44_RS10915	COG4208	sulfate ABC transporter
IAG44_RS10925	COG0820	rRNA (adenine-C2-)-methyltransferase activity
IAG44_RS10935	COG0575	Belongs to the CDS family
IAG44_RS10940	COG0233	cytoplasmic translational termination
IAG44_RS10945	COG0528	UMP kinase activity
IAG44_RS10950	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IAG44_RS10955	COG0052	Belongs to the universal ribosomal protein uS2 family
IAG44_RS10970	COG1191	sigma factor activity
IAG44_RS10985	COG0792	nuclease activity
IAG44_RS10995	COG0494	nUDIX hydrolase
IAG44_RS11005	COG0681	Belongs to the peptidase S26 family
IAG44_RS11010	COG0681	Belongs to the peptidase S26 family
IAG44_RS11015	COG0681	Belongs to the peptidase S26 family
IAG44_RS11020	COG0335	large ribosomal subunit rRNA binding
IAG44_RS11025	COG0336	Belongs to the RNA methyltransferase TrmD family
IAG44_RS11030	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IAG44_RS11035	COG1837	Belongs to the UPF0109 family
IAG44_RS11040	COG0228	four-way junction DNA binding
IAG44_RS11050	COG0442	prolyl-tRNA aminoacylation
IAG44_RS11060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IAG44_RS11070	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
IAG44_RS11105	COG0477	Major facilitator Superfamily
IAG44_RS11110	COG1196	nuclear chromosome segregation
IAG44_RS11120	COG1254	Belongs to the acylphosphatase family
IAG44_RS11125	COG2340	Cysteine-rich secretory protein family
IAG44_RS11130	COG1733	regulation of RNA biosynthetic process
IAG44_RS11135	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IAG44_RS11140	COG0571	ribonuclease III activity
IAG44_RS11145	COG0333	Belongs to the bacterial ribosomal protein bL32 family
IAG44_RS11160	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IAG44_RS11165	COG0742	ribosomal rna small subunit methyltransferase
IAG44_RS11175	COG0326	Molecular chaperone. Has ATPase activity
IAG44_RS11185	COG1461	Dihydroxyacetone kinase
IAG44_RS11190	COG0227	Belongs to the bacterial ribosomal protein bL28 family
IAG44_RS11195	COG0351	phosphomethylpyrimidine kinase
IAG44_RS11215	COG1181	Belongs to the D-alanine--D-alanine ligase family
IAG44_RS11220	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
IAG44_RS11230	COG1920	GTP binding
IAG44_RS11240	COG0776	regulation of translation
IAG44_RS11250	COG0066	3-isopropylmalate dehydratase activity
IAG44_RS11255	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IAG44_RS11260	COG1414	Transcriptional regulator
IAG44_RS11295	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IAG44_RS11300	COG0179	Fumarylacetoacetate (FAA) hydrolase
IAG44_RS11310	COG5002	protein histidine kinase activity
IAG44_RS11315	COG2018	Roadblock/LC7 domain
IAG44_RS11335	COG2018	Roadblock/LC7 domain
IAG44_RS11360	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IAG44_RS11375	COG4552	Acetyltransferase involved in intracellular survival and related
IAG44_RS11380	COG3903	Transcriptional regulator
IAG44_RS11380	COG3629	intracellular signal transduction
IAG44_RS11415	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IAG44_RS11420	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IAG44_RS11425	COG0473	3-isopropylmalate dehydrogenase activity
IAG44_RS11440	COG1012	belongs to the aldehyde dehydrogenase family
IAG44_RS11445	COG0506	proline dehydrogenase activity
IAG44_RS11450	COG3835	regulator
IAG44_RS11455	COG4166	transmembrane transport
IAG44_RS11460	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAG44_RS11470	COG4608	Belongs to the ABC transporter superfamily
IAG44_RS11480	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IAG44_RS11485	COG0440	acetolactate synthase activity
IAG44_RS11495	COG5001	Diguanylate cyclase
IAG44_RS11505	COG0667	Aldo Keto reductase
IAG44_RS11510	COG2133	pyrroloquinoline quinone binding
IAG44_RS11520	COG2197	response regulator
IAG44_RS11535	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IAG44_RS11540	COG2409	Drug exporters of the RND superfamily
IAG44_RS11550	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IAG44_RS11560	COG0154	amidase activity
IAG44_RS11565	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IAG44_RS11575	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IAG44_RS11590	COG4221	oxidoreductase activity
IAG44_RS11605	COG0482	sulfurtransferase activity
IAG44_RS11610	COG3023	N-Acetylmuramoyl-L-alanine amidase
IAG44_RS11620	COG1028	Short-chain dehydrogenase reductase Sdr
IAG44_RS11645	COG2378	regulation of single-species biofilm formation
IAG44_RS11665	COG2860	membrane
IAG44_RS11675	COG4608	Belongs to the ABC transporter superfamily
IAG44_RS11680	COG0444	Belongs to the ABC transporter superfamily
IAG44_RS11690	COG0747	negative chemotaxis
IAG44_RS11695	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAG44_RS11715	COG0404	The glycine cleavage system catalyzes the degradation of glycine
IAG44_RS11720	COG0509	glycine decarboxylation via glycine cleavage system
IAG44_RS11725	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IAG44_RS11730	COG1760	l-serine dehydratase
IAG44_RS11735	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IAG44_RS11745	COG2313	pseudouridylate synthase activity
IAG44_RS11755	COG2807	transmembrane transport
IAG44_RS11760	COG2188	Transcriptional regulator
IAG44_RS11800	COG2085	NADP oxidoreductase coenzyme F420-dependent
IAG44_RS11840	COG3119	arylsulfatase activity
IAG44_RS11850	COG1376	ErfK ybiS ycfS ynhG family protein
IAG44_RS11855	COG1376	ErfK ybiS ycfS ynhG family protein
IAG44_RS11870	COG2197	response regulator
IAG44_RS11875	COG4585	Histidine kinase
IAG44_RS11885	COG1131	(ABC) transporter
IAG44_RS11890	COG1132	(ABC) transporter
IAG44_RS11900	COG1132	(ABC) transporter
IAG44_RS11905	COG1132	(ABC) transporter
IAG44_RS11925	COG0058	SHG alpha-glucan phosphorylase activity
IAG44_RS11935	COG0366	Alpha amylase catalytic
IAG44_RS11945	COG3281	Trehalose synthase
IAG44_RS11950	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IAG44_RS11970	COG3118	belongs to the thioredoxin family
IAG44_RS11975	COG0789	Transcriptional regulator
IAG44_RS12000	COG3290	protein histidine kinase activity
IAG44_RS12005	COG4565	transcriptional regulatory protein
IAG44_RS12015	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IAG44_RS12025	COG0205	6-phosphofructokinase activity
IAG44_RS12030	COG0280	phosphate acetyltransferase
IAG44_RS12030	COG0857	belongs to the CobB CobQ family
IAG44_RS12035	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IAG44_RS12160	COG2205	protein histidine kinase activity
IAG44_RS12165	COG0745	RESPONSE REGULATOR receiver
IAG44_RS12185	COG0183	Belongs to the thiolase family
IAG44_RS12285	COG0464	growth
IAG44_RS12295	COG0823	Involved in the tonB-independent uptake of proteins
IAG44_RS12310	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
IAG44_RS12345	COG1131	(ABC) transporter
IAG44_RS12365	COG2026	Addiction module toxin, RelE StbE family
IAG44_RS12380	COG4585	Histidine kinase
IAG44_RS12390	COG2197	response regulator
IAG44_RS12410	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IAG44_RS12415	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IAG44_RS12420	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IAG44_RS12425	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IAG44_RS12430	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IAG44_RS12435	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IAG44_RS12440	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IAG44_RS12455	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IAG44_RS12460	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IAG44_RS12465	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IAG44_RS12475	COG2890	protein-(glutamine-N5) methyltransferase activity
IAG44_RS12480	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IAG44_RS12485	COG0254	rRNA binding
IAG44_RS12500	COG0083	homoserine kinase activity
IAG44_RS12505	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IAG44_RS12510	COG0460	homoserine dehydrogenase
IAG44_RS12515	COG0019	diaminopimelate decarboxylase activity
IAG44_RS12520	COG0018	arginyl-trna synthetase
IAG44_RS12520	COG0018	arginyl-trna synthetase
IAG44_RS12525	COG0745	RESPONSE REGULATOR receiver
IAG44_RS12550	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IAG44_RS12620	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IAG44_RS12630	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IAG44_RS12635	COG3903	Transcriptional regulator
IAG44_RS12635	COG3629	intracellular signal transduction
IAG44_RS12655	COG1609	Transcriptional regulator
IAG44_RS12720	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
IAG44_RS12725	COG1793	dna ligase
IAG44_RS12725	COG3285	dna ligase
IAG44_RS12745	COG2205	protein histidine kinase activity
IAG44_RS12800	COG0789	Transcriptional regulator
IAG44_RS12800	COG4978	Transcriptional regulator
IAG44_RS12815	COG1902	pentaerythritol trinitrate reductase activity
IAG44_RS12855	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IAG44_RS12885	COG0745	RESPONSE REGULATOR receiver
IAG44_RS12890	COG2205	protein histidine kinase activity
IAG44_RS12895	COG0567	Dehydrogenase, E1 component
IAG44_RS12895	COG0508	dehydrogenase complex catalyzes the overall conversion of
IAG44_RS12965	COG0604	alcohol dehydrogenase
IAG44_RS12970	COG0281	malic enzyme
IAG44_RS12990	COG4106	trans-aconitate 2-methyltransferase activity
IAG44_RS13050	COG0456	acetyltransferase
IAG44_RS13085	COG0142	geranyltranstransferase activity
IAG44_RS13090	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IAG44_RS13095	COG2515	1-aminocyclopropane-1-carboxylate deaminase
IAG44_RS13135	COG1597	lipid kinase activity
IAG44_RS13150	COG0363	glucosamine-6-phosphate deaminase activity
IAG44_RS13155	COG1472	Belongs to the glycosyl hydrolase 3 family
IAG44_RS13160	COG2188	Transcriptional regulator
IAG44_RS13190	COG2124	cytochrome p450
IAG44_RS13200	COG0242	peptide deformylase activity
IAG44_RS13220	COG5662	AntiSigma factor
IAG44_RS13225	COG1595	DNA-templated transcription, initiation
IAG44_RS13235	COG2135	peptidase activity
IAG44_RS13245	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IAG44_RS13255	COG2076	Multidrug Resistance protein
IAG44_RS13265	COG0483	inositol monophosphate 1-phosphatase activity
IAG44_RS13295	COG1615	UPF0182 protein
IAG44_RS13305	COG3480	Lon protease (S16) C-terminal proteolytic domain
IAG44_RS13310	COG0314	molybdopterin synthase activity
IAG44_RS13360	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IAG44_RS13395	COG2816	NAD+ diphosphatase activity
IAG44_RS13405	COG0210	DNA helicase
IAG44_RS13410	COG0210	DNA helicase
IAG44_RS13430	COG0596	Alpha beta hydrolase
IAG44_RS13475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAG44_RS13480	COG0747	negative chemotaxis
IAG44_RS13520	COG0513	Belongs to the DEAD box helicase family
IAG44_RS13530	COG1432	Conserved Protein
IAG44_RS13540	COG2095	MarC family integral membrane protein
IAG44_RS13555	COG2814	Major facilitator Superfamily
IAG44_RS13565	COG0598	Magnesium transport protein CorA
IAG44_RS13600	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IAG44_RS13605	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IAG44_RS13615	COG1595	DNA-templated transcription, initiation
IAG44_RS13630	COG1024	Enoyl-CoA hydratase
IAG44_RS13635	COG2818	Glycosylase
IAG44_RS13660	COG1611	Belongs to the LOG family
IAG44_RS13665	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IAG44_RS13705	COG2197	response regulator
IAG44_RS13710	COG4585	Histidine kinase
IAG44_RS13715	COG0842	Transport permease protein
IAG44_RS13720	COG1131	(ABC) transporter
IAG44_RS13735	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IAG44_RS13750	COG4608	Belongs to the ABC transporter superfamily
IAG44_RS13760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAG44_RS13765	COG0601	transmembrane transport
IAG44_RS13790	COG0601	transmembrane transport
IAG44_RS13795	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAG44_RS13810	COG4608	Belongs to the ABC transporter superfamily
IAG44_RS13820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAG44_RS13825	COG0601	transmembrane transport
IAG44_RS13830	COG4166	transmembrane transport
IAG44_RS13840	COG1217	gtp-binding protein TYPA
IAG44_RS13860	COG1053	succinate dehydrogenase
IAG44_RS13930	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IAG44_RS13935	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IAG44_RS13950	COG1028	Short-chain dehydrogenase reductase Sdr
IAG44_RS13985	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IAG44_RS14000	COG0012	GTP binding
IAG44_RS14015	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IAG44_RS14020	COG1570	exodeoxyribonuclease VII activity
IAG44_RS14025	COG1722	exodeoxyribonuclease VII activity
IAG44_RS14030	COG0778	Nitroreductase
IAG44_RS14035	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IAG44_RS14035	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IAG44_RS14060	COG0114	fumarate hydratase activity
IAG44_RS14075	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IAG44_RS14090	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IAG44_RS14130	COG2186	Transcriptional regulator
IAG44_RS14155	COG0450	alkyl hydroperoxide reductase
IAG44_RS14160	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IAG44_RS14170	COG0741	lytic transglycosylase activity
IAG44_RS14175	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
IAG44_RS14180	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IAG44_RS14225	COG2197	response regulator
IAG44_RS14260	COG2894	cell division
IAG44_RS14275	COG1396	sequence-specific DNA binding
IAG44_RS14275	COG3800	Transcriptional regulator
IAG44_RS14345	COG0436	Aminotransferase
IAG44_RS14400	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
IAG44_RS14410	COG0477	Major facilitator Superfamily
IAG44_RS14415	COG1309	transcriptional regulator
IAG44_RS14445	COG1331	Highly conserved protein containing a thioredoxin domain
IAG44_RS14485	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IAG44_RS14495	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IAG44_RS14510	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IAG44_RS14515	COG2255	four-way junction helicase activity
IAG44_RS14550	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IAG44_RS14560	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IAG44_RS14565	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IAG44_RS14575	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IAG44_RS14580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAG44_RS14585	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAG44_RS14590	COG1064	alcohol dehydrogenase
IAG44_RS14625	COG1136	(ABC) transporter
IAG44_RS14665	COG2986	histidine ammonia-lyase
IAG44_RS14675	COG1024	Enoyl-CoA hydratase
IAG44_RS14685	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
IAG44_RS14695	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IAG44_RS14710	COG0424	maF-like protein
IAG44_RS14720	COG4770	biotin carboxylase activity
IAG44_RS14745	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IAG44_RS14760	COG1012	belongs to the aldehyde dehydrogenase family
IAG44_RS14765	COG1012	belongs to the aldehyde dehydrogenase family
IAG44_RS14780	COG1595	DNA-templated transcription, initiation
IAG44_RS14785	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
IAG44_RS14790	COG0745	RESPONSE REGULATOR receiver
IAG44_RS14795	COG2205	protein histidine kinase activity
IAG44_RS14825	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IAG44_RS14835	COG0583	DNA-binding transcription factor activity
IAG44_RS14840	COG2814	Major facilitator Superfamily
IAG44_RS14885	COG1079	Belongs to the binding-protein-dependent transport system permease family
IAG44_RS14895	COG3845	ABC transporter
IAG44_RS14900	COG1744	ABC transporter substrate-binding protein PnrA-like
IAG44_RS14905	COG1744	ABC transporter substrate-binding protein PnrA-like
IAG44_RS14910	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
IAG44_RS14910	COG1473	amidohydrolase
IAG44_RS14925	COG2226	methyltransferase
IAG44_RS14945	COG2089	acid synthase
IAG44_RS14970	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IAG44_RS14985	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IAG44_RS14985	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IAG44_RS14995	COG1595	DNA-templated transcription, initiation
IAG44_RS15020	COG3525	Glycosyl hydrolase, family 20, catalytic domain
IAG44_RS15030	COG2009	succinate dehydrogenase
IAG44_RS15040	COG1053	succinate dehydrogenase
IAG44_RS15085	COG1309	transcriptional regulator
IAG44_RS15095	COG2409	Drug exporters of the RND superfamily
IAG44_RS15100	COG0745	RESPONSE REGULATOR receiver
IAG44_RS15105	COG2205	protein histidine kinase activity
IAG44_RS15110	COG0747	negative chemotaxis
IAG44_RS15115	COG1408	metallophosphoesterase
IAG44_RS15135	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IAG44_RS15175	COG1686	Belongs to the peptidase S11 family
IAG44_RS15180	COG1295	ribonuclease BN
IAG44_RS15205	COG0180	Tryptophanyl-tRNA synthetase
IAG44_RS15210	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IAG44_RS15220	COG0754	glutathionylspermidine amidase activity
IAG44_RS15235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IAG44_RS15240	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IAG44_RS15285	COG0039	L-malate dehydrogenase activity
IAG44_RS15325	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IAG44_RS15340	COG0515	serine threonine protein kinase
IAG44_RS15345	COG0138	bifunctional purine biosynthesis protein purh
IAG44_RS15375	COG0045	succinate-CoA ligase (ADP-forming) activity
IAG44_RS15380	COG3552	Protein containing von Willebrand factor type A (VWA) domain
IAG44_RS15385	COG2425	protein containing a von Willebrand factor type A (vWA) domain
IAG44_RS15390	COG0714	Associated with various cellular activities
IAG44_RS15405	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IAG44_RS15405	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IAG44_RS15425	COG0791	NLP P60 protein
IAG44_RS15425	COG0741	lytic transglycosylase activity
IAG44_RS15440	COG2197	response regulator
IAG44_RS15485	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IAG44_RS15485	COG0519	Catalyzes the synthesis of GMP from XMP
IAG44_RS15510	COG1012	belongs to the aldehyde dehydrogenase family
IAG44_RS15515	COG0515	serine threonine protein kinase
IAG44_RS15515	COG2815	serine threonine protein kinase
IAG44_RS15520	COG0515	serine threonine protein kinase
IAG44_RS15520	COG2815	serine threonine protein kinase
IAG44_RS15525	COG0515	serine threonine protein kinase
IAG44_RS15525	COG2815	serine threonine protein kinase
IAG44_RS15540	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IAG44_RS15550	COG0516	GMP reductase activity
IAG44_RS15560	COG1595	DNA-templated transcription, initiation
IAG44_RS15575	COG0583	DNA-binding transcription factor activity
IAG44_RS15585	COG4221	oxidoreductase activity
IAG44_RS15590	COG0459	protein refolding
IAG44_RS15600	COG0726	polysaccharide deacetylase
IAG44_RS15605	COG0726	polysaccharide deacetylase
IAG44_RS15620	COG4941	Belongs to the sigma-70 factor family
IAG44_RS15655	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IAG44_RS15675	COG0802	atpase or kinase
IAG44_RS15685	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IAG44_RS15695	COG0736	holo-[acyl-carrier-protein] synthase activity
IAG44_RS15710	COG3864	Putative metallopeptidase domain
IAG44_RS15715	COG0714	Associated with various cellular activities
IAG44_RS15730	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IAG44_RS15750	COG1072	(Pantothenic acid kinase))
IAG44_RS15760	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IAG44_RS15765	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IAG44_RS15770	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IAG44_RS15780	COG0101	tRNA pseudouridine synthase activity
IAG44_RS15785	COG0203	ribosomal protein L17
IAG44_RS15790	COG0202	RNA polymerase activity
IAG44_RS15795	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IAG44_RS15800	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IAG44_RS15805	COG0257	Belongs to the bacterial ribosomal protein bL36 family
IAG44_RS15810	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IAG44_RS15825	COG0563	adenylate kinase activity
IAG44_RS15830	COG0201	protein transport
IAG44_RS15835	COG0200	Binds to the 23S rRNA
IAG44_RS15840	COG1841	ribosomal large subunit assembly
IAG44_RS15845	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IAG44_RS15850	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IAG44_RS15855	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IAG44_RS15860	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IAG44_RS15865	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IAG44_RS15870	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IAG44_RS15875	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IAG44_RS15880	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IAG44_RS15885	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IAG44_RS15890	COG0255	Belongs to the universal ribosomal protein uL29 family
IAG44_RS15895	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IAG44_RS15900	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IAG44_RS15905	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IAG44_RS15910	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IAG44_RS15915	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IAG44_RS15920	COG0089	rRNA binding
IAG44_RS15925	COG0088	Forms part of the polypeptide exit tunnel
IAG44_RS15930	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IAG44_RS15935	COG0051	transcription antitermination factor activity, RNA binding
IAG44_RS15940	COG0667	Aldo Keto reductase
IAG44_RS15945	COG1472	Belongs to the glycosyl hydrolase 3 family
IAG44_RS15955	COG2124	cytochrome p450
IAG44_RS16065	COG2755	lipolytic protein G-D-S-L family
IAG44_RS16065	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IAG44_RS16070	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IAG44_RS16075	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IAG44_RS16080	COG0049	tRNA binding
IAG44_RS16085	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IAG44_RS16090	COG0463	Glycosyl transferase, family 2
IAG44_RS16105	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IAG44_RS16110	COG0085	RNA polymerase activity
IAG44_RS16120	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IAG44_RS16135	COG0081	regulation of translation
IAG44_RS16145	COG0250	Participates in transcription elongation, termination and antitermination
IAG44_RS16160	COG0436	Aminotransferase
IAG44_RS16165	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IAG44_RS16180	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IAG44_RS16185	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IAG44_RS16195	COG2030	dehydratase
IAG44_RS16200	COG0267	Belongs to the bacterial ribosomal protein bL33 family
IAG44_RS16215	COG0402	S-adenosylhomocysteine deaminase activity
IAG44_RS16220	COG0702	epimerase
IAG44_RS16295	COG0270	DNA (cytosine-5-)-methyltransferase activity
IAG44_RS16325	COG1666	GTP binding
IAG44_RS16330	COG2261	transglycosylase associated protein
IAG44_RS16340	COG3304	Inner membrane component domain
IAG44_RS16345	COG0501	Belongs to the peptidase M48B family
IAG44_RS16350	COG1007	ATP synthesis coupled electron transport
IAG44_RS16360	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IAG44_RS16365	COG0713	ATP synthesis coupled electron transport
IAG44_RS16370	COG0839	Belongs to the complex I subunit 6 family
IAG44_RS16375	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IAG44_RS16380	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
IAG44_RS16385	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IAG44_RS16385	COG0649	NAD binding
IAG44_RS16390	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IAG44_RS16395	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IAG44_RS16415	COG0674	pyruvate-flavodoxin oxidoreductase activity
IAG44_RS16415	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
IAG44_RS16420	COG1013	pyruvate-flavodoxin oxidoreductase activity
IAG44_RS16425	COG1733	regulation of RNA biosynthetic process
IAG44_RS16430	COG0702	epimerase
IAG44_RS16470	COG1131	(ABC) transporter
IAG44_RS16480	COG0142	geranyltranstransferase activity
IAG44_RS16490	COG0561	phosphatase activity
IAG44_RS16545	COG0514	ATP-dependent DNA helicase (RecQ)
IAG44_RS16550	COG1007	ATP synthesis coupled electron transport
IAG44_RS16560	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IAG44_RS16565	COG0713	ATP synthesis coupled electron transport
IAG44_RS16570	COG0839	Belongs to the complex I subunit 6 family
IAG44_RS16575	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IAG44_RS16580	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
IAG44_RS16585	COG1034	ATP synthesis coupled electron transport
IAG44_RS16590	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IAG44_RS16600	COG0649	NAD binding
IAG44_RS16605	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IAG44_RS16610	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IAG44_RS16620	COG0791	NLP P60 protein
IAG44_RS16645	COG2226	methyltransferase
IAG44_RS16655	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
IAG44_RS16670	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
IAG44_RS16675	COG1278	Cold shock
IAG44_RS16705	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
IAG44_RS16715	COG0183	Belongs to the thiolase family
IAG44_RS16720	COG1028	Short-chain dehydrogenase reductase Sdr
IAG44_RS16730	COG1309	transcriptional regulator
IAG44_RS16745	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
IAG44_RS16755	COG0163	prenyltransferase activity
IAG44_RS16770	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
IAG44_RS16780	COG2318	DinB family
IAG44_RS16785	COG0515	serine threonine protein kinase
IAG44_RS16785	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IAG44_RS16820	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IAG44_RS16830	COG0785	Cytochrome C biogenesis protein
IAG44_RS16845	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IAG44_RS16850	COG0406	alpha-ribazole phosphatase activity
IAG44_RS16880	COG0431	NADPH-dependent FMN reductase
IAG44_RS16885	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAG44_RS16900	COG1733	regulation of RNA biosynthetic process
IAG44_RS16925	COG1690	Belongs to the RtcB family
IAG44_RS16945	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
IAG44_RS16955	COG0018	arginyl-trna synthetase
IAG44_RS17000	COG0113	porphobilinogen synthase activity
IAG44_RS17005	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IAG44_RS17005	COG1648	precorrin-2 dehydrogenase activity
IAG44_RS17010	COG0181	hydroxymethylbilane synthase activity
IAG44_RS17015	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IAG44_RS17020	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IAG44_RS17070	COG0123	including yeast histone deacetylase and acetoin utilization protein
IAG44_RS17080	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IAG44_RS17105	COG0180	Tryptophanyl-tRNA synthetase
IAG44_RS17110	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IAG44_RS17120	COG0842	Transport permease protein
IAG44_RS17120	COG1129	ABC transporter
IAG44_RS17125	COG0659	secondary active sulfate transmembrane transporter activity
IAG44_RS17145	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IAG44_RS17145	COG0515	serine threonine protein kinase
IAG44_RS17150	COG0129	dihydroxy-acid dehydratase activity
IAG44_RS17160	COG1082	Xylose isomerase domain protein TIM barrel
IAG44_RS17165	COG0248	Ppx GppA phosphatase
IAG44_RS17185	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
IAG44_RS17195	COG1194	a g-specific adenine glycosylase
IAG44_RS17200	COG1595	DNA-templated transcription, initiation
IAG44_RS17210	COG0745	RESPONSE REGULATOR receiver
IAG44_RS17215	COG2205	protein histidine kinase activity
IAG44_RS17220	COG0477	Major facilitator Superfamily
IAG44_RS17230	COG0739	heme binding
IAG44_RS17230	COG1196	nuclear chromosome segregation
IAG44_RS17230	COG0741	lytic transglycosylase activity
IAG44_RS17255	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IAG44_RS17275	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IAG44_RS17285	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
IAG44_RS17290	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IAG44_RS17305	COG0640	Transcriptional regulator
IAG44_RS17310	COG2197	response regulator
IAG44_RS17325	COG0649	NAD binding
IAG44_RS17350	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IAG44_RS17350	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IAG44_RS17365	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IAG44_RS17380	COG0302	gtp cyclohydrolase
IAG44_RS17395	COG0037	tRNA processing
IAG44_RS17405	COG2027	D-alanyl-D-alanine carboxypeptidase
IAG44_RS17410	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IAG44_RS17420	COG0586	Pfam SNARE associated Golgi protein
IAG44_RS17425	COG0393	Putative heavy-metal-binding
IAG44_RS17430	COG0789	Transcriptional regulator
IAG44_RS17450	COG2318	DinB family
IAG44_RS17455	COG1012	belongs to the aldehyde dehydrogenase family
IAG44_RS17475	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IAG44_RS17485	COG0254	rRNA binding
IAG44_RS17490	COG0267	Belongs to the bacterial ribosomal protein bL33 family
IAG44_RS17495	COG0227	Belongs to the bacterial ribosomal protein bL28 family
IAG44_RS17500	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IAG44_RS17520	COG1404	Belongs to the peptidase S8 family
IAG44_RS17570	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IAG44_RS17570	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IAG44_RS17610	COG4555	ABC transporter
IAG44_RS17640	COG0585	pseudouridine synthase activity
IAG44_RS17655	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IAG44_RS17665	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IAG44_RS17695	COG0456	acetyltransferase
IAG44_RS17695	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IAG44_RS17700	COG2226	methyltransferase
IAG44_RS17705	COG0105	UTP biosynthetic process
IAG44_RS17790	COG3321	synthase
IAG44_RS17790	COG4221	oxidoreductase activity
IAG44_RS17790	COG0300	oxidoreductase activity
IAG44_RS17790	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IAG44_RS17795	COG0367	asparagine synthase
IAG44_RS17810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IAG44_RS17820	COG2085	NADP oxidoreductase coenzyme F420-dependent
IAG44_RS17840	COG1028	Short-chain dehydrogenase reductase Sdr
IAG44_RS17875	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IAG44_RS17880	COG0640	Transcriptional regulator
IAG44_RS17890	COG1942	4-Oxalocrotonate Tautomerase
IAG44_RS17895	COG2814	Major facilitator Superfamily
IAG44_RS17900	COG0583	DNA-binding transcription factor activity
IAG44_RS17905	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IAG44_RS17930	COG4191	Histidine kinase
IAG44_RS17975	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IAG44_RS17980	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IAG44_RS17985	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IAG44_RS17985	COG1754	DNA topoisomerase type I activity
IAG44_RS17995	COG2264	protein methyltransferase activity
IAG44_RS18005	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
IAG44_RS18015	COG1366	Belongs to the anti-sigma-factor antagonist family
IAG44_RS18020	COG1205	dead DEAH box helicase
IAG44_RS18020	COG1111	helicase
IAG44_RS18080	COG0288	reversible hydration of carbon dioxide
IAG44_RS18085	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IAG44_RS18100	COG2267	carboxylic ester hydrolase activity
IAG44_RS18130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IAG44_RS18155	COG0003	Pfam Anion-transporting ATPase
IAG44_RS18165	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IAG44_RS18175	COG1408	metallophosphoesterase
IAG44_RS18200	COG2255	four-way junction helicase activity
IAG44_RS18210	COG1376	ErfK ybiS ycfS ynhG family protein
IAG44_RS18225	COG0701	Predicted permease
IAG44_RS18250	COG1595	DNA-templated transcription, initiation
IAG44_RS18275	COG2205	protein histidine kinase activity
IAG44_RS18295	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IAG44_RS18300	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IAG44_RS18310	COG2205	protein histidine kinase activity
IAG44_RS18315	COG0745	RESPONSE REGULATOR receiver
IAG44_RS18340	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IAG44_RS18350	COG2197	response regulator
IAG44_RS18365	COG1802	Transcriptional regulator
IAG44_RS18370	COG0463	Glycosyl transferase, family 2
IAG44_RS18380	COG0737	Belongs to the 5'-nucleotidase family
IAG44_RS18390	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IAG44_RS18405	COG1131	(ABC) transporter
IAG44_RS18410	COG3559	Exporter of polyketide antibiotics
IAG44_RS18420	COG2124	cytochrome p450
IAG44_RS18470	COG2197	response regulator
IAG44_RS18475	COG4585	Histidine kinase
IAG44_RS18480	COG2197	response regulator
IAG44_RS18485	COG4585	Histidine kinase
IAG44_RS18505	COG3844	kynureninase activity
IAG44_RS18525	COG0191	fructose-bisphosphate aldolase activity
IAG44_RS18530	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IAG44_RS18545	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IAG44_RS18570	COG0542	response to heat
IAG44_RS18620	COG4213	ABC transporter substrate-binding protein
IAG44_RS18625	COG0789	Transcriptional regulator
IAG44_RS18630	COG0484	heat shock protein binding
IAG44_RS18635	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IAG44_RS18640	COG0443	Heat shock 70 kDa protein
IAG44_RS18645	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IAG44_RS18660	COG0247	lactate metabolic process
IAG44_RS18660	COG2181	nitrate reductase activity
IAG44_RS18670	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IAG44_RS18750	COG1609	Transcriptional regulator
IAG44_RS18755	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
IAG44_RS18760	COG0717	Belongs to the dCTP deaminase family
IAG44_RS18780	COG0714	Associated with various cellular activities
IAG44_RS18835	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IAG44_RS18855	COG2755	lipolytic protein G-D-S-L family
IAG44_RS18860	COG0515	serine threonine protein kinase
IAG44_RS18860	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IAG44_RS18890	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
IAG44_RS18895	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
IAG44_RS18900	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
IAG44_RS18915	COG0483	inositol monophosphate 1-phosphatase activity
IAG44_RS18930	COG4208	sulfate ABC transporter
IAG44_RS18950	COG1253	flavin adenine dinucleotide binding
IAG44_RS18965	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IAG44_RS19050	COG2319	Wd-40 repeat
IAG44_RS19050	COG4249	Peptidase C14 caspase catalytic subunit p20
IAG44_RS19120	COG0546	phosphoglycolate phosphatase activity
IAG44_RS19125	COG2186	Transcriptional regulator
IAG44_RS19135	COG2188	Transcriptional regulator
IAG44_RS19140	COG4552	Acetyltransferase involved in intracellular survival and related
IAG44_RS19155	COG1490	D-aminoacyl-tRNA deacylase activity
IAG44_RS19170	COG3485	protocatechuate 3,4-dioxygenase
IAG44_RS19220	COG0667	Aldo Keto reductase
IAG44_RS19240	COG2897	thiosulfate sulfurtransferase activity
IAG44_RS19265	COG0745	RESPONSE REGULATOR receiver
IAG44_RS19270	COG1609	Transcriptional regulator
IAG44_RS19275	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IAG44_RS19295	COG0456	acetyltransferase
IAG44_RS19345	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IAG44_RS19350	COG1957	nucleoside hydrolase
IAG44_RS19430	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IAG44_RS19435	COG3866	Pectate lyase
IAG44_RS19445	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IAG44_RS19475	COG1741	Belongs to the pirin family
IAG44_RS19480	COG1278	Cold shock
IAG44_RS19485	COG0513	Belongs to the DEAD box helicase family
IAG44_RS19500	COG1960	acyl-CoA dehydrogenase activity
IAG44_RS19510	COG4249	Peptidase C14 caspase catalytic subunit p20
IAG44_RS19510	COG2319	Wd-40 repeat
IAG44_RS19530	COG1196	nuclear chromosome segregation
IAG44_RS19565	COG1362	aminopeptidase activity
IAG44_RS19580	COG0493	'glutamate synthase
IAG44_RS19585	COG2814	Major facilitator Superfamily
IAG44_RS19595	COG0363	glucosamine-6-phosphate deaminase activity
IAG44_RS19600	COG1472	Belongs to the glycosyl hydrolase 3 family
IAG44_RS19675	COG1131	(ABC) transporter
IAG44_RS19720	COG0508	dehydrogenase complex catalyzes the overall conversion of
IAG44_RS19725	COG0022	dehydrogenase e1 component
IAG44_RS19745	COG0515	serine threonine protein kinase
IAG44_RS19750	COG0515	serine threonine protein kinase
IAG44_RS19765	COG1028	Short-chain dehydrogenase reductase Sdr
IAG44_RS19765	COG3321	synthase
IAG44_RS19765	COG0604	alcohol dehydrogenase
IAG44_RS19780	COG0303	'Molybdopterin
IAG44_RS19805	COG1522	sequence-specific DNA binding
IAG44_RS19840	COG1309	transcriptional regulator
IAG44_RS19845	COG1250	3-hydroxyacyl-CoA dehydrogenase
IAG44_RS19875	COG3460	Phenylacetate-CoA oxygenase
IAG44_RS19880	COG3396	Phenylacetate-CoA oxygenase
IAG44_RS19885	COG2151	metal-sulfur cluster biosynthetic enzyme
IAG44_RS19890	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IAG44_RS19900	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IAG44_RS19935	COG1716	ATPase activity
IAG44_RS19940	COG1716	ATPase activity
IAG44_RS19955	COG0768	penicillin binding
IAG44_RS19960	COG0515	serine threonine protein kinase
IAG44_RS19970	COG3764	Sortase (surface protein transpeptidase)
IAG44_RS19975	COG3764	Sortase (surface protein transpeptidase)
IAG44_RS19990	COG3764	Sortase (surface protein transpeptidase)
IAG44_RS20005	COG0705	Rhomboid family
IAG44_RS20025	COG0475	glutathione-regulated potassium exporter activity
IAG44_RS20060	COG1316	TRANSCRIPTIONal
IAG44_RS20145	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IAG44_RS20255	COG1051	belongs to the nudix hydrolase family
IAG44_RS20290	COG1484	DNA-dependent DNA replication
IAG44_RS20335	COG0741	lytic transglycosylase activity
IAG44_RS20335	COG0739	heme binding
IAG44_RS20335	COG1196	nuclear chromosome segregation
IAG44_RS20430	COG0105	UTP biosynthetic process
IAG44_RS20605	COG0582	viral genome integration into host DNA
IAG44_RS20620	COG0515	serine threonine protein kinase
IAG44_RS20655	COG2391	methyltransferase activity
IAG44_RS20670	COG3266	domain, Protein
IAG44_RS20675	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IAG44_RS20680	COG0187	DNA topoisomerase II activity
IAG44_RS20685	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
IAG44_RS20690	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IAG44_RS20695	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
IAG44_RS20700	COG0592	DNA-directed DNA polymerase activity
IAG44_RS20705	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IAG44_RS20715	COG0594	ribonuclease P activity
IAG44_RS20720	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
IAG44_RS20725	COG0706	membrane insertase activity
IAG44_RS20735	COG0357	Ribosomal RNA small subunit methyltransferase G
IAG44_RS20740	COG1192	Involved in chromosome partitioning
IAG44_RS20755	COG3118	belongs to the thioredoxin family
IAG44_RS20760	COG0492	ferredoxin-NADP+ reductase activity
IAG44_RS20770	COG1595	DNA-templated transcription, initiation
IAG44_RS20775	COG2815	serine threonine protein kinase
IAG44_RS20775	COG0515	serine threonine protein kinase
IAG44_RS20790	COG0617	tRNA 3'-terminal CCA addition
IAG44_RS20805	COG1260	myo-inositol-1-phosphate synthase
IAG44_RS20815	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
IAG44_RS20840	COG0360	Binds together with S18 to 16S ribosomal RNA
IAG44_RS20845	COG0629	single-stranded DNA binding
IAG44_RS20850	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IAG44_RS20855	COG0359	binds to the 23S rRNA
IAG44_RS20865	COG0305	Participates in initiation and elongation during chromosome replication
IAG44_RS20885	COG2814	Major facilitator Superfamily
IAG44_RS20910	COG0626	cystathionine gamma-synthase activity
IAG44_RS20915	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IAG44_RS20920	COG1950	PFAM Membrane protein of
IAG44_RS20925	COG0662	Cupin 2, conserved barrel domain protein
IAG44_RS20950	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IAG44_RS20965	COG1609	Transcriptional regulator
IAG44_RS20970	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IAG44_RS20975	COG1271	oxidase subunit
IAG44_RS20980	COG1294	oxidase, subunit
IAG44_RS20985	COG4988	ABC transporter
IAG44_RS20995	COG0741	lytic transglycosylase activity
IAG44_RS20995	COG0739	heme binding
IAG44_RS20995	COG1196	nuclear chromosome segregation
IAG44_RS21000	COG0561	phosphatase activity
IAG44_RS21010	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
IAG44_RS21035	COG1131	(ABC) transporter
IAG44_RS21055	COG0561	phosphatase activity
IAG44_RS21060	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IAG44_RS21065	COG0077	Prephenate dehydratase
IAG44_RS21070	COG2837	iron assimilation
IAG44_RS21075	COG1276	copper resistance
IAG44_RS21105	COG0006	proline dipeptidase activity
IAG44_RS21130	COG0653	protein targeting
IAG44_RS21145	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IAG44_RS21195	COG1595	DNA-templated transcription, initiation
IAG44_RS21205	COG0318	PFAM AMP-dependent synthetase and ligase
IAG44_RS21240	COG2814	Major facilitator Superfamily
IAG44_RS21245	COG1309	transcriptional regulator
IAG44_RS21250	COG0784	Response regulator, receiver
IAG44_RS21275	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IAG44_RS21290	COG0494	nUDIX hydrolase
IAG44_RS21295	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IAG44_RS21325	COG0745	RESPONSE REGULATOR receiver
IAG44_RS21330	COG2205	protein histidine kinase activity
IAG44_RS21340	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IAG44_RS21345	COG0477	Major facilitator Superfamily
IAG44_RS21355	COG3467	pyridoxamine 5'-phosphate
IAG44_RS21385	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
IAG44_RS21425	COG1191	sigma factor activity
IAG44_RS21430	COG1191	sigma factor activity
IAG44_RS21550	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IAG44_RS21565	COG0433	COG0433 Predicted ATPase
IAG44_RS21620	COG0477	Major facilitator Superfamily
IAG44_RS21630	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
IAG44_RS21655	COG0151	Belongs to the GarS family
IAG44_RS21670	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
IAG44_RS21680	COG2197	response regulator
IAG44_RS21715	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IAG44_RS21720	COG0047	phosphoribosylformylglycinamidine synthase activity
IAG44_RS21725	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IAG44_RS21755	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IAG44_RS21765	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IAG44_RS21785	COG1643	Atp-dependent helicase
IAG44_RS21825	COG0513	Belongs to the DEAD box helicase family
IAG44_RS21840	COG1595	DNA-templated transcription, initiation
IAG44_RS21855	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IAG44_RS21865	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IAG44_RS21865	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IAG44_RS21885	COG0667	Aldo Keto reductase
IAG44_RS21895	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IAG44_RS21900	COG0579	oxidoreductase
IAG44_RS21965	COG1252	NADH dehydrogenase
IAG44_RS21970	COG1366	Belongs to the anti-sigma-factor antagonist family
IAG44_RS21970	COG2172	sigma factor antagonist activity
IAG44_RS21970	COG2208	phosphoserine phosphatase activity
IAG44_RS22040	COG1309	transcriptional regulator
IAG44_RS22060	COG0741	lytic transglycosylase activity
IAG44_RS22060	COG0739	heme binding
IAG44_RS22060	COG1196	nuclear chromosome segregation
IAG44_RS22065	COG0671	phosphoesterase, PA-phosphatase related
IAG44_RS22070	COG0277	FAD linked oxidase domain protein
IAG44_RS22090	COG0306	phosphate transporter
IAG44_RS22100	COG1937	Protein conserved in bacteria
IAG44_RS22115	COG4106	trans-aconitate 2-methyltransferase activity
IAG44_RS22150	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IAG44_RS22170	COG0406	alpha-ribazole phosphatase activity
IAG44_RS22170	COG0494	nUDIX hydrolase
IAG44_RS22180	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IAG44_RS22195	COG3842	ATPase activity
IAG44_RS22200	COG1725	Transcriptional regulator
IAG44_RS22215	COG1131	(ABC) transporter
IAG44_RS22235	COG0456	acetyltransferase
IAG44_RS22240	COG0737	Belongs to the 5'-nucleotidase family
IAG44_RS22250	COG1136	(ABC) transporter
IAG44_RS22310	COG3842	ATPase activity
IAG44_RS22320	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IAG44_RS22330	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IAG44_RS22335	COG0215	cysteine-tRNA ligase activity
IAG44_RS22340	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
IAG44_RS22345	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
IAG44_RS22350	COG1329	Transcriptional regulator
IAG44_RS22365	COG5002	protein histidine kinase activity
IAG44_RS22415	COG0588	phosphoglycerate mutase activity
IAG44_RS22450	COG0438	transferase activity, transferring glycosyl groups
IAG44_RS22490	COG0789	Transcriptional regulator
IAG44_RS22495	COG2130	NADP-dependent
IAG44_RS22500	COG4977	sequence-specific DNA binding
IAG44_RS22510	COG1733	regulation of RNA biosynthetic process
IAG44_RS22525	COG1252	NADH dehydrogenase
IAG44_RS22530	COG1595	DNA-templated transcription, initiation
IAG44_RS22560	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IAG44_RS22565	COG1316	TRANSCRIPTIONal
IAG44_RS22585	COG3708	Transcriptional regulator
IAG44_RS22585	COG2207	Transcriptional regulator
IAG44_RS22605	COG0596	Alpha beta hydrolase
IAG44_RS22620	COG0494	nUDIX hydrolase
IAG44_RS22660	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IAG44_RS22685	COG1105	Belongs to the carbohydrate kinase PfkB family
IAG44_RS22690	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IAG44_RS22720	COG0463	Glycosyl transferase, family 2
IAG44_RS22735	COG1278	Cold shock
IAG44_RS22740	COG0459	protein refolding
IAG44_RS22820	COG3896	Chloramphenicol phosphotransferase-like protein
IAG44_RS22835	COG3629	intracellular signal transduction
IAG44_RS22835	COG3903	Transcriptional regulator
IAG44_RS22840	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IAG44_RS22845	COG1737	Transcriptional regulator
IAG44_RS22880	COG3973	AAA domain
IAG44_RS22900	COG1061	Type III restriction enzyme res subunit
IAG44_RS22935	COG1278	Cold shock
IAG44_RS22940	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
IAG44_RS22945	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IAG44_RS22955	COG2814	Major facilitator Superfamily
IAG44_RS22995	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IAG44_RS23005	COG2252	PERMEase
IAG44_RS23035	COG0667	Aldo Keto reductase
IAG44_RS23080	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IAG44_RS23085	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IAG44_RS23090	COG0277	FAD linked oxidase domain protein
IAG44_RS23090	COG0247	lactate metabolic process
IAG44_RS23100	COG1132	(ABC) transporter
IAG44_RS23105	COG5006	permease, DMT superfamily
IAG44_RS23130	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IAG44_RS23145	COG0318	PFAM AMP-dependent synthetase and ligase
IAG44_RS23165	COG0259	pyridoxamine-phosphate oxidase activity
IAG44_RS23190	COG4821	SIS domain
IAG44_RS23200	COG2945	thiolester hydrolase activity
IAG44_RS23200	COG0596	Alpha beta hydrolase
IAG44_RS23245	COG1366	Belongs to the anti-sigma-factor antagonist family
IAG44_RS23255	COG0318	PFAM AMP-dependent synthetase and ligase
IAG44_RS23265	COG1960	acyl-CoA dehydrogenase activity
IAG44_RS23270	COG1960	acyl-CoA dehydrogenase activity
IAG44_RS23285	COG1028	Short-chain dehydrogenase reductase Sdr
IAG44_RS23290	COG1960	acyl-CoA dehydrogenase activity
IAG44_RS23320	COG1024	Enoyl-CoA hydratase
IAG44_RS23350	COG2072	flavoprotein involved in K transport
IAG44_RS23355	COG1231	oxidoreductase activity
IAG44_RS23395	COG1960	acyl-CoA dehydrogenase activity
IAG44_RS23405	COG1309	transcriptional regulator
IAG44_RS23415	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IAG44_RS23415	COG0515	serine threonine protein kinase
IAG44_RS23425	COG2267	carboxylic ester hydrolase activity
IAG44_RS23430	COG1024	Enoyl-CoA hydratase
IAG44_RS23495	COG1012	belongs to the aldehyde dehydrogenase family
IAG44_RS23535	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
IAG44_RS23580	COG1686	Belongs to the peptidase S11 family
IAG44_RS23635	COG0386	Belongs to the glutathione peroxidase family
IAG44_RS23695	COG3226	Transcriptional regulator
IAG44_RS23700	COG0738	Major facilitator superfamily
IAG44_RS23740	COG1414	Transcriptional regulator
IAG44_RS23760	COG1846	Transcriptional regulator
IAG44_RS23765	COG3384	dioxygenase
IAG44_RS23770	COG1247	-acetyltransferase
IAG44_RS23775	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IAG44_RS23785	COG1349	DNA-binding transcription factor activity
IAG44_RS23795	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IAG44_RS23795	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IAG44_RS23795	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IAG44_RS23810	COG3191	aminopeptidase activity
IAG44_RS23825	COG1970	mechanosensitive ion channel activity
IAG44_RS23835	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IAG44_RS23860	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IAG44_RS23865	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IAG44_RS23875	COG0315	cyclic pyranopterin monophosphate synthase activity
IAG44_RS23880	COG0521	Mo-molybdopterin cofactor biosynthetic process
IAG44_RS23880	COG0315	cyclic pyranopterin monophosphate synthase activity
IAG44_RS23920	COG1136	(ABC) transporter
IAG44_RS23920	COG0577	efflux transmembrane transporter activity
IAG44_RS23930	COG2201	protein-glutamate methylesterase activity
IAG44_RS23940	COG0708	Exodeoxyribonuclease III
IAG44_RS23950	COG2072	flavoprotein involved in K transport
IAG44_RS23955	COG2267	carboxylic ester hydrolase activity
IAG44_RS23960	COG1028	Short-chain dehydrogenase reductase Sdr
IAG44_RS23970	COG4946	Tricorn protease homolog
IAG44_RS23970	COG0793	Belongs to the peptidase S41A family
IAG44_RS23980	COG2409	Drug exporters of the RND superfamily
IAG44_RS23995	COG0442	prolyl-tRNA aminoacylation
IAG44_RS24020	COG1764	response to oxidative stress
IAG44_RS24035	COG1846	Transcriptional regulator
IAG44_RS24040	COG1122	ATPase activity
IAG44_RS24050	COG0310	cobalt ion transport
IAG44_RS24065	COG0768	penicillin binding
IAG44_RS24095	COG0084	hydrolase, TatD family'
IAG44_RS24110	COG2188	Transcriptional regulator
IAG44_RS24130	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IAG44_RS24140	COG3583	domain protein
IAG44_RS24140	COG3584	3D domain protein
IAG44_RS24145	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IAG44_RS24150	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IAG44_RS24165	COG0488	(ABC) transporter
IAG44_RS24205	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IAG44_RS24225	COG0586	Pfam SNARE associated Golgi protein
IAG44_RS24250	COG2197	response regulator
IAG44_RS24255	COG1846	Transcriptional regulator
IAG44_RS24260	COG4106	trans-aconitate 2-methyltransferase activity
IAG44_RS24280	COG1309	transcriptional regulator
IAG44_RS24290	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IAG44_RS24300	COG0193	aminoacyl-tRNA hydrolase activity
IAG44_RS24305	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IAG44_RS24310	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IAG44_RS24315	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IAG44_RS24330	COG4585	Histidine kinase
IAG44_RS24360	COG2814	Major facilitator Superfamily
IAG44_RS24365	COG1136	(ABC) transporter
IAG44_RS24370	COG0577	efflux transmembrane transporter activity
IAG44_RS24435	COG1131	(ABC) transporter
IAG44_RS24490	COG2124	cytochrome p450
IAG44_RS24505	COG0148	phosphopyruvate hydratase activity
IAG44_RS24530	COG1252	NADH dehydrogenase
IAG44_RS24565	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IAG44_RS24570	COG0577	efflux transmembrane transporter activity
IAG44_RS24575	COG1136	(ABC) transporter
IAG44_RS24610	COG0183	Belongs to the thiolase family
IAG44_RS24620	COG2755	lipolytic protein G-D-S-L family
IAG44_RS24680	COG0019	diaminopimelate decarboxylase activity
IAG44_RS24685	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IAG44_RS24700	COG1228	amidohydrolase
IAG44_RS24705	COG1191	sigma factor activity
IAG44_RS24710	COG1366	Belongs to the anti-sigma-factor antagonist family
IAG44_RS24735	COG3104	oligopeptide transport
IAG44_RS24740	COG0745	RESPONSE REGULATOR receiver
IAG44_RS24745	COG2205	protein histidine kinase activity
IAG44_RS24780	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IAG44_RS24800	COG1316	TRANSCRIPTIONal
IAG44_RS24810	COG1404	Belongs to the peptidase S8 family
IAG44_RS24835	COG1316	TRANSCRIPTIONal
IAG44_RS24845	COG1316	TRANSCRIPTIONal
IAG44_RS24850	COG1316	TRANSCRIPTIONal
IAG44_RS24855	COG1316	TRANSCRIPTIONal
IAG44_RS24880	COG0778	Nitroreductase
IAG44_RS24880	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
IAG44_RS24885	COG0391	Required for morphogenesis under gluconeogenic growth conditions
IAG44_RS24925	COG2835	tetraacyldisaccharide 4'-kinase activity
IAG44_RS24935	COG1482	cell wall glycoprotein biosynthetic process
IAG44_RS24945	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IAG44_RS24985	COG0714	Associated with various cellular activities
IAG44_RS25005	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
IAG44_RS25010	COG0745	RESPONSE REGULATOR receiver
IAG44_RS25015	COG5002	protein histidine kinase activity
IAG44_RS25015	COG5000	phosphorelay sensor kinase activity
IAG44_RS25020	COG0823	Involved in the tonB-independent uptake of proteins
IAG44_RS25030	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IAG44_RS25035	COG2197	response regulator
IAG44_RS25040	COG3214	Protein conserved in bacteria
IAG44_RS25045	COG0653	protein targeting
IAG44_RS25065	COG2902	Dehydrogenase
IAG44_RS25070	COG1134	teichoic acid transport
IAG44_RS25120	COG1846	Transcriptional regulator
IAG44_RS25125	COG1764	response to oxidative stress
IAG44_RS25145	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IAG44_RS25150	COG0463	Glycosyl transferase, family 2
IAG44_RS25150	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IAG44_RS25155	COG0395	ABC-type sugar transport system, permease component
IAG44_RS25160	COG1175	transmembrane transport
IAG44_RS25170	COG1674	ftsk spoiiie
IAG44_RS25175	COG0515	serine threonine protein kinase
IAG44_RS25180	COG0515	serine threonine protein kinase
IAG44_RS25185	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IAG44_RS25200	COG2884	Cell division ATP-binding protein ftsE
IAG44_RS25205	COG2177	Part of the ABC transporter FtsEX involved in
IAG44_RS25210	COG0793	Belongs to the peptidase S41A family
IAG44_RS25215	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IAG44_RS25230	COG1501	Belongs to the glycosyl hydrolase 31 family
IAG44_RS25240	COG1175	transmembrane transport
IAG44_RS25245	COG1653	transport
IAG44_RS25255	COG0583	DNA-binding transcription factor activity
IAG44_RS25320	COG2223	nitrite transmembrane transporter activity
IAG44_RS25340	COG3973	AAA domain
IAG44_RS25350	COG0776	regulation of translation
IAG44_RS25355	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IAG44_RS25360	COG1678	Uncharacterized ACR, COG1678
IAG44_RS25380	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IAG44_RS25410	COG3654	unkown
IAG44_RS25440	COG1174	glycine betaine transport
IAG44_RS25450	COG1174	glycine betaine transport
IAG44_RS25465	COG0277	FAD linked oxidase domain protein
IAG44_RS25510	COG1278	Cold shock
IAG44_RS25515	COG1335	isochorismatase
IAG44_RS25525	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IAG44_RS25540	COG1113	amino acid transport
IAG44_RS25570	COG1263	PTS System
IAG44_RS25575	COG1263	PTS System
IAG44_RS25580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IAG44_RS25585	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IAG44_RS25595	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IAG44_RS25635	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IAG44_RS25650	COG4555	ABC transporter
IAG44_RS25660	COG2733	membrane
IAG44_RS25705	COG1074	ATP-dependent DNA helicase activity
IAG44_RS25735	COG0270	DNA (cytosine-5-)-methyltransferase activity
IAG44_RS25760	COG3764	Sortase (surface protein transpeptidase)
IAG44_RS25770	COG0706	membrane insertase activity
IAG44_RS25780	COG4702	Belongs to the UPF0303 family
IAG44_RS25785	COG0673	inositol 2-dehydrogenase activity
IAG44_RS25840	COG0318	PFAM AMP-dependent synthetase and ligase
IAG44_RS25855	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IAG44_RS25870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAG44_RS25920	COG0406	alpha-ribazole phosphatase activity
IAG44_RS25945	COG0395	ABC-type sugar transport system, permease component
IAG44_RS25985	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IAG44_RS25990	COG4977	sequence-specific DNA binding
IAG44_RS26000	COG0589	response to stress
IAG44_RS26010	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IAG44_RS26040	COG3486	L-lysine 6-monooxygenase (NADPH) activity
IAG44_RS26060	COG1960	acyl-CoA dehydrogenase activity
IAG44_RS26075	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IAG44_RS26080	COG1309	transcriptional regulator
IAG44_RS26090	COG1946	Acyl-CoA thioesterase
IAG44_RS26105	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IAG44_RS26115	COG3960	tartronate-semialdehyde synthase activity
IAG44_RS26135	COG2356	endonuclease I
IAG44_RS26140	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IAG44_RS26185	COG0395	ABC-type sugar transport system, permease component
IAG44_RS26190	COG1175	transmembrane transport
IAG44_RS26200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAG44_RS26210	COG1609	Transcriptional regulator
IAG44_RS26225	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IAG44_RS26270	COG0673	inositol 2-dehydrogenase activity
IAG44_RS26300	COG1869	D-ribose catabolic process
IAG44_RS26305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IAG44_RS26315	COG1129	ABC transporter
IAG44_RS26365	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IAG44_RS26375	COG0494	nUDIX hydrolase
IAG44_RS26400	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IAG44_RS26415	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IAG44_RS26425	COG3718	enzyme involved in inositol metabolism
IAG44_RS26430	COG3962	Belongs to the TPP enzyme family
IAG44_RS26470	COG1131	(ABC) transporter
IAG44_RS26515	COG0492	ferredoxin-NADP+ reductase activity
IAG44_RS26540	COG0438	transferase activity, transferring glycosyl groups
IAG44_RS26560	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IAG44_RS26565	COG0297	glycogen (starch) synthase activity
IAG44_RS26605	COG2304	oxidoreductase activity
IAG44_RS26635	COG0583	DNA-binding transcription factor activity
IAG44_RS26640	COG0697	spore germination
IAG44_RS26645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAG44_RS26660	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IAG44_RS26665	COG1454	alcohol dehydrogenase
IAG44_RS26700	COG0515	serine threonine protein kinase
IAG44_RS26705	COG0438	transferase activity, transferring glycosyl groups
IAG44_RS26705	COG1216	Glycosyl transferase, family 2
IAG44_RS26730	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IAG44_RS26735	COG0629	single-stranded DNA binding
IAG44_RS26800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IAG44_RS26810	COG0668	transmembrane transport
IAG44_RS26825	COG1136	(ABC) transporter
IAG44_RS26835	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IAG44_RS26870	COG0697	spore germination
IAG44_RS26875	COG1846	Transcriptional regulator
IAG44_RS26900	COG0583	DNA-binding transcription factor activity
IAG44_RS26985	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IAG44_RS27000	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IAG44_RS27005	COG1113	amino acid transport
IAG44_RS27020	COG0515	serine threonine protein kinase
IAG44_RS27025	COG1113	amino acid transport
IAG44_RS27060	COG0544	peptidyl-prolyl cis-trans isomerase activity
IAG44_RS27065	COG0740	serine-type endopeptidase activity
IAG44_RS27070	COG0740	serine-type endopeptidase activity
IAG44_RS27075	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IAG44_RS27085	COG0525	valine-tRNA ligase activity
IAG44_RS27095	COG0285	dihydrofolate synthase activity
IAG44_RS27105	COG0105	UTP biosynthetic process
IAG44_RS27110	COG1077	Cell shape determining protein MreB Mrl
IAG44_RS27125	COG0768	penicillin binding
IAG44_RS27130	COG0772	Belongs to the SEDS family
IAG44_RS27160	COG1530	ribonuclease E activity
IAG44_RS27165	COG0261	This protein binds to 23S rRNA in the presence of protein L20
IAG44_RS27170	COG0211	Belongs to the bacterial ribosomal protein bL27 family
IAG44_RS27175	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IAG44_RS27185	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IAG44_RS27190	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IAG44_RS27200	COG1216	Glycosyl transferase, family 2
IAG44_RS27230	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
IAG44_RS27235	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IAG44_RS27245	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IAG44_RS27260	COG0501	Belongs to the peptidase M48B family
IAG44_RS27275	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IAG44_RS27285	COG0799	negative regulation of ribosome biogenesis
IAG44_RS27290	COG0588	phosphoglycerate mutase activity
IAG44_RS27310	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IAG44_RS27320	COG0495	leucyl-tRNA aminoacylation
IAG44_RS27330	COG1307	EDD domain protein, DegV family
IAG44_RS27335	COG1555	photosystem II stabilization
IAG44_RS27335	COG1596	polysaccharide export
IAG44_RS27355	COG0268	Binds directly to 16S ribosomal RNA
IAG44_RS27360	COG0481	GTPase activity
IAG44_RS27400	COG1420	regulation of RNA biosynthetic process
IAG44_RS27405	COG0484	heat shock protein binding
IAG44_RS27420	COG4946	Tricorn protease homolog
IAG44_RS27420	COG0793	Belongs to the peptidase S41A family
IAG44_RS27425	COG0537	adenosine 5'-monophosphoramidase activity
IAG44_RS27430	COG1234	tRNA 3'-trailer cleavage
IAG44_RS27435	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IAG44_RS27465	COG4948	Mandelate Racemase Muconate Lactonizing
IAG44_RS27470	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IAG44_RS27480	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IAG44_RS27490	COG2315	Protein conserved in bacteria
IAG44_RS27530	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IAG44_RS27560	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IAG44_RS27590	COG1381	Involved in DNA repair and RecF pathway recombination
IAG44_RS27595	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IAG44_RS27610	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IAG44_RS27615	COG1120	ATPase activity
IAG44_RS27620	COG0803	Belongs to the bacterial solute-binding protein 9 family
IAG44_RS27620	COG3443	Belongs to the bacterial solute-binding protein 9 family
IAG44_RS27625	COG0423	glycine-tRNA ligase activity
IAG44_RS27660	COG1940	carbohydrate kinase activity
IAG44_RS27660	COG1846	Transcriptional regulator
IAG44_RS27665	COG0574	Belongs to the PEP-utilizing enzyme family
IAG44_RS27665	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IAG44_RS27670	COG4221	oxidoreductase activity
IAG44_RS27685	COG0745	RESPONSE REGULATOR receiver
IAG44_RS27690	COG2205	protein histidine kinase activity
IAG44_RS27700	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IAG44_RS27700	COG2146	nitrite reductase [NAD(P)H] activity
IAG44_RS27755	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
IAG44_RS27800	COG0477	Major facilitator Superfamily
IAG44_RS27820	COG2949	membrane
IAG44_RS27830	COG0232	Belongs to the dGTPase family. Type 2 subfamily
IAG44_RS27840	COG0358	DNA primase activity
IAG44_RS27855	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IAG44_RS27870	COG1070	Carbohydrate kinase
IAG44_RS27895	COG2272	Belongs to the type-B carboxylesterase lipase family
IAG44_RS27920	COG4585	Histidine kinase
IAG44_RS27925	COG2197	response regulator
IAG44_RS27940	COG1653	transport
IAG44_RS27945	COG1175	transmembrane transport
IAG44_RS27950	COG0395	ABC-type sugar transport system, permease component
IAG44_RS27965	COG1077	Cell shape determining protein MreB Mrl
IAG44_RS27970	COG0515	serine threonine protein kinase
IAG44_RS27970	COG2815	serine threonine protein kinase
IAG44_RS27975	COG2255	four-way junction helicase activity
IAG44_RS27990	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IAG44_RS27990	COG0825	malonyl-CoA metabolic process
IAG44_RS27995	COG0318	PFAM AMP-dependent synthetase and ligase
IAG44_RS28005	COG2186	Transcriptional regulator
IAG44_RS28025	COG1414	Transcriptional regulator
IAG44_RS28030	COG3386	PFAM SMP-30 Gluconolaconase
IAG44_RS28055	COG1175	transmembrane transport
IAG44_RS28060	COG0395	ABC-type sugar transport system, permease component
IAG44_RS28065	COG3507	Belongs to the glycosyl hydrolase 43 family
IAG44_RS28085	COG3507	Belongs to the glycosyl hydrolase 43 family
IAG44_RS28090	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IAG44_RS28100	COG4214	carbohydrate transport
IAG44_RS28105	COG1129	ABC transporter
IAG44_RS28145	COG2130	NADP-dependent
IAG44_RS28180	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IAG44_RS28185	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IAG44_RS28190	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IAG44_RS28205	COG1741	Belongs to the pirin family
IAG44_RS28210	COG0515	serine threonine protein kinase
IAG44_RS28210	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IAG44_RS28220	COG0789	Transcriptional regulator
IAG44_RS28235	COG1309	transcriptional regulator
IAG44_RS28240	COG0477	Major facilitator Superfamily
IAG44_RS28250	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
IAG44_RS28295	COG1358	cellular component organization or biogenesis
IAG44_RS28310	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IAG44_RS28345	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IAG44_RS28395	COG3629	intracellular signal transduction
IAG44_RS28395	COG3903	Transcriptional regulator
IAG44_RS28400	COG1595	DNA-templated transcription, initiation
IAG44_RS28405	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
IAG44_RS28460	COG4122	O-methyltransferase activity
IAG44_RS28490	COG0183	Belongs to the thiolase family
IAG44_RS28495	COG2124	cytochrome p450
IAG44_RS28525	COG1309	transcriptional regulator
IAG44_RS28530	COG0438	transferase activity, transferring glycosyl groups
IAG44_RS28555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAG44_RS28565	COG2247	cell wall binding repeat
IAG44_RS28565	COG0860	N-Acetylmuramoyl-L-alanine amidase
IAG44_RS28590	COG2197	response regulator
IAG44_RS28595	COG4585	Histidine kinase
IAG44_RS28600	COG2030	dehydratase
IAG44_RS28610	COG1028	Short-chain dehydrogenase reductase Sdr
IAG44_RS28615	COG0537	adenosine 5'-monophosphoramidase activity
IAG44_RS28630	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IAG44_RS28645	COG3022	response to hydroperoxide
IAG44_RS28700	COG0438	transferase activity, transferring glycosyl groups
IAG44_RS28745	COG1686	Belongs to the peptidase S11 family
IAG44_RS28750	COG1028	Short-chain dehydrogenase reductase Sdr
IAG44_RS28760	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IAG44_RS28775	COG0673	inositol 2-dehydrogenase activity
IAG44_RS28795	COG0672	)-iron permease
IAG44_RS28800	COG2837	iron assimilation
IAG44_RS28810	COG1120	ATPase activity
IAG44_RS28815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAG44_RS28865	COG2197	response regulator
IAG44_RS28870	COG4585	Histidine kinase
IAG44_RS28880	COG1994	Peptidase M50
IAG44_RS28910	COG2814	Major facilitator Superfamily
IAG44_RS28925	COG0477	Major facilitator Superfamily
IAG44_RS28930	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IAG44_RS28935	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IAG44_RS28935	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IAG44_RS28960	COG0174	glutamine synthetase
IAG44_RS28970	COG2402	Toxic component of a toxin-antitoxin (TA) module. An RNase
IAG44_RS28975	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
IAG44_RS28985	COG1609	Transcriptional regulator
IAG44_RS28990	COG2182	Extracellular solute-binding protein
IAG44_RS28995	COG1175	transmembrane transport
IAG44_RS29000	COG3833	ABC-type maltose transport systems, permease component
IAG44_RS29005	COG0366	Alpha amylase catalytic
IAG44_RS29030	COG1309	transcriptional regulator
IAG44_RS29065	COG2197	response regulator
IAG44_RS29070	COG4585	Histidine kinase
IAG44_RS29080	COG0745	RESPONSE REGULATOR receiver
IAG44_RS29120	COG0501	Belongs to the peptidase M48B family
IAG44_RS29130	COG0174	glutamine synthetase
IAG44_RS29150	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IAG44_RS29155	COG0321	lipoyl(octanoyl) transferase activity
IAG44_RS29180	COG1233	COG1233 Phytoene dehydrogenase and related
IAG44_RS29250	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
IAG44_RS29265	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IAG44_RS29270	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IAG44_RS29280	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
IAG44_RS29300	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
IAG44_RS29345	COG4585	Histidine kinase
IAG44_RS29350	COG2197	response regulator
IAG44_RS29355	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IAG44_RS29360	COG0515	serine threonine protein kinase
IAG44_RS29360	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IAG44_RS29395	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IAG44_RS29410	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IAG44_RS29420	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IAG44_RS29425	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IAG44_RS29435	COG1376	ErfK ybiS ycfS ynhG family protein
IAG44_RS29445	COG1845	cytochrome c oxidase, subunit III
IAG44_RS29450	COG2010	Cytochrome c
IAG44_RS29455	COG0723	plastoquinol--plastocyanin reductase activity
IAG44_RS29460	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IAG44_RS29465	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IAG44_RS29470	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IAG44_RS29515	COG0534	Mate efflux family protein
IAG44_RS29530	COG1022	Amp-dependent synthetase and ligase
IAG44_RS29545	COG0003	Pfam Anion-transporting ATPase
IAG44_RS29555	COG1940	carbohydrate kinase activity
IAG44_RS29580	COG4585	Histidine kinase
IAG44_RS29590	COG0205	6-phosphofructokinase activity
IAG44_RS29605	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
IAG44_RS29610	COG0243	molybdopterin cofactor binding
IAG44_RS29615	COG2193	ferroxidase activity
IAG44_RS29620	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IAG44_RS29635	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IAG44_RS29640	COG0515	serine threonine protein kinase
IAG44_RS29640	COG2815	serine threonine protein kinase
IAG44_RS29645	COG2022	thiamine diphosphate biosynthetic process
IAG44_RS29655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IAG44_RS29655	COG2022	thiamine diphosphate biosynthetic process
IAG44_RS29675	COG0352	thiamine-phosphate diphosphorylase activity
IAG44_RS29690	COG1233	COG1233 Phytoene dehydrogenase and related
IAG44_RS29700	COG1309	transcriptional regulator
IAG44_RS29710	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IAG44_RS29730	COG0714	Associated with various cellular activities
IAG44_RS29740	COG0275	rRNA processing
IAG44_RS29750	COG0768	penicillin binding
IAG44_RS29755	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IAG44_RS29765	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IAG44_RS29770	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IAG44_RS29780	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IAG44_RS29785	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IAG44_RS29790	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IAG44_RS29795	COG1496	oxidoreductase activity
IAG44_RS29805	COG1799	cell septum assembly
IAG44_RS29815	COG3599	regulation of cell shape
IAG44_RS29820	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IAG44_RS29825	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IAG44_RS29830	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IAG44_RS29880	COG0587	DNA-directed DNA polymerase activity
IAG44_RS29890	COG1432	Conserved Protein
IAG44_RS29910	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IAG44_RS29930	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IAG44_RS29935	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IAG44_RS29940	COG0131	Imidazoleglycerol-phosphate dehydratase
IAG44_RS29950	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IAG44_RS29955	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IAG44_RS29960	COG0251	oxidation-reduction process
IAG44_RS29965	COG0107	imidazoleglycerol-phosphate synthase activity
IAG44_RS29985	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IAG44_RS30010	COG0134	indole-3-glycerol-phosphate synthase activity
IAG44_RS30015	COG0133	tryptophan synthase activity
IAG44_RS30020	COG0159	tryptophan synthase activity
IAG44_RS30030	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IAG44_RS30040	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IAG44_RS30045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IAG44_RS30065	COG1397	ADP-ribosylglycohydrolase
IAG44_RS30075	COG0070	glutamate synthase
IAG44_RS30075	COG0069	glutamate synthase activity
IAG44_RS30075	COG0067	glutamate synthase
IAG44_RS30085	COG0667	Aldo Keto reductase
IAG44_RS30095	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IAG44_RS30100	COG0183	Belongs to the thiolase family
IAG44_RS30115	COG0287	Prephenate dehydrogenase
IAG44_RS30115	COG1605	Chorismate mutase
IAG44_RS30145	COG0737	Belongs to the 5'-nucleotidase family
IAG44_RS30185	COG0411	ABC transporter
IAG44_RS30205	COG2050	protein possibly involved in aromatic compounds catabolism
IAG44_RS30240	COG1643	Atp-dependent helicase
IAG44_RS30245	COG2226	methyltransferase
IAG44_RS30260	COG0237	dephospho-CoA kinase activity
IAG44_RS30280	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IAG44_RS30290	COG2267	carboxylic ester hydrolase activity
IAG44_RS30295	COG1802	Transcriptional regulator
IAG44_RS30300	COG1953	Uracil, thiamine, allantoin
IAG44_RS30345	COG0402	S-adenosylhomocysteine deaminase activity
IAG44_RS30360	COG1132	(ABC) transporter
IAG44_RS30385	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IAG44_RS30390	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IAG44_RS30420	COG0598	Magnesium transport protein CorA
IAG44_RS30425	COG2226	methyltransferase
IAG44_RS30430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IAG44_RS30435	COG2313	pseudouridylate synthase activity
IAG44_RS30445	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IAG44_RS30450	COG0584	glycerophosphoryl diester phosphodiesterase
IAG44_RS30460	COG0556	nucleotide-excision repair
IAG44_RS30480	COG0387	Pfam Sodium calcium exchanger
IAG44_RS30485	COG0477	Major facilitator Superfamily
IAG44_RS30495	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
IAG44_RS30505	COG0765	amino acid transport
IAG44_RS30510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IAG44_RS30525	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IAG44_RS30540	COG0322	excinuclease ABC activity
IAG44_RS30545	COG1660	Displays ATPase and GTPase activities
IAG44_RS30550	COG0391	Required for morphogenesis under gluconeogenic growth conditions
IAG44_RS30555	COG1481	regulation of sporulation
IAG44_RS30565	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IAG44_RS30570	COG0126	phosphoglycerate kinase activity
IAG44_RS30575	COG0149	triose-phosphate isomerase activity
IAG44_RS30580	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IAG44_RS30595	COG0363	glucosamine-6-phosphate deaminase activity
IAG44_RS30610	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IAG44_RS30620	COG0109	protoheme IX farnesyltransferase activity
IAG44_RS30650	COG3693	PFAM glycoside hydrolase, family 10
IAG44_RS30655	COG2746	aminoglycoside 3-N-acetyltransferase activity
IAG44_RS30670	COG0719	Fe-S assembly protein
IAG44_RS30680	COG0396	ATPase activity
IAG44_RS30685	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IAG44_RS30690	COG0822	iron-sulfur transferase activity
IAG44_RS30695	COG2151	metal-sulfur cluster biosynthetic enzyme
IAG44_RS30705	COG2076	Multidrug Resistance protein
IAG44_RS30710	COG3226	Transcriptional regulator
IAG44_RS30715	COG2171	N-acyltransferase activity
IAG44_RS30720	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IAG44_RS30765	COG0641	radical SAM
IAG44_RS30815	COG1802	Transcriptional regulator
IAG44_RS30825	COG1609	Transcriptional regulator
IAG44_RS30835	COG1175	transmembrane transport
IAG44_RS30840	COG0395	ABC-type sugar transport system, permease component
IAG44_RS30855	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IAG44_RS30860	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IAG44_RS30865	COG1349	DNA-binding transcription factor activity
IAG44_RS30875	COG1175	transmembrane transport
IAG44_RS30880	COG0395	ABC-type sugar transport system, permease component
IAG44_RS30885	COG1063	alcohol dehydrogenase
IAG44_RS30890	COG1404	Belongs to the peptidase S8 family
IAG44_RS30930	COG1234	tRNA 3'-trailer cleavage
IAG44_RS30935	COG1802	Transcriptional regulator
IAG44_RS30940	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IAG44_RS30950	COG1175	transmembrane transport
IAG44_RS30955	COG0395	ABC-type sugar transport system, permease component
IAG44_RS30960	COG3866	Pectate lyase
IAG44_RS30980	COG4677	pectinesterase activity
IAG44_RS30990	COG2755	lipolytic protein G-D-S-L family
IAG44_RS31000	COG4677	pectinesterase activity
IAG44_RS31005	COG4677	pectinesterase activity
IAG44_RS31030	COG1595	DNA-templated transcription, initiation
IAG44_RS31035	COG2252	PERMEase
IAG44_RS31045	COG1414	Transcriptional regulator
IAG44_RS31065	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IAG44_RS31070	COG1846	Transcriptional regulator
IAG44_RS31075	COG1902	pentaerythritol trinitrate reductase activity
IAG44_RS31080	COG2318	DinB family
IAG44_RS31085	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IAG44_RS31095	COG0765	amino acid transport
IAG44_RS31100	COG1126	abc transporter atp-binding protein
IAG44_RS31120	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
IAG44_RS31155	COG1797	cobyrinic acid a,c-diamide synthase activity
IAG44_RS31175	COG1492	cobalamin metabolic process
IAG44_RS31180	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
IAG44_RS31195	COG0235	Class ii aldolase
IAG44_RS31215	COG0488	(ABC) transporter
IAG44_RS31265	COG3387	PFAM Glycoside hydrolase 15-related
IAG44_RS31280	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IAG44_RS31285	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IAG44_RS31305	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IAG44_RS31310	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IAG44_RS31325	COG2261	transglycosylase associated protein
IAG44_RS31330	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IAG44_RS31345	COG1028	Short-chain dehydrogenase reductase Sdr
IAG44_RS31360	COG2186	Transcriptional regulator
IAG44_RS31365	COG2807	transmembrane transport
IAG44_RS31375	COG0588	phosphoglycerate mutase activity
IAG44_RS31380	COG3830	Belongs to the UPF0237 family
IAG44_RS31380	COG0560	Phosphoserine phosphatase
IAG44_RS31390	COG0842	Transport permease protein
IAG44_RS31390	COG1716	ATPase activity
IAG44_RS31390	COG1131	(ABC) transporter
IAG44_RS31405	COG2197	response regulator
IAG44_RS31425	COG1119	ATPase activity
IAG44_RS31445	COG1881	PFAM PEBP family protein
IAG44_RS31455	COG2094	Belongs to the DNA glycosylase MPG family
IAG44_RS31490	COG0647	UMP catabolic process
IAG44_RS31495	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAG44_RS31500	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAG44_RS31505	COG1120	ATPase activity
IAG44_RS31525	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IAG44_RS31530	COG0497	DNA recombination
IAG44_RS31535	COG0438	transferase activity, transferring glycosyl groups
IAG44_RS31545	COG3387	PFAM Glycoside hydrolase 15-related
IAG44_RS31550	COG0504	CTP synthase activity
IAG44_RS31555	COG0494	nUDIX hydrolase
IAG44_RS31565	COG0686	Belongs to the AlaDH PNT family
IAG44_RS31580	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IAG44_RS31585	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IAG44_RS31590	COG1187	pseudouridine synthase activity
IAG44_RS31600	COG1397	ADP-ribosylglycohydrolase
IAG44_RS31615	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
IAG44_RS31625	COG1160	GTP binding
IAG44_RS31640	COG1652	LysM domain
IAG44_RS31645	COG3583	domain protein
IAG44_RS31655	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IAG44_RS31665	COG0671	phosphoesterase, PA-phosphatase related
IAG44_RS31675	COG0477	Major facilitator Superfamily
IAG44_RS31680	COG1960	acyl-CoA dehydrogenase activity
IAG44_RS31685	COG1799	cell septum assembly
IAG44_RS31705	COG0330	HflC and HflK could
IAG44_RS31740	COG1725	Transcriptional regulator
IAG44_RS31755	COG1215	transferase activity, transferring glycosyl groups
IAG44_RS31770	COG2755	lipolytic protein G-D-S-L family
IAG44_RS31775	COG2815	serine threonine protein kinase
IAG44_RS31775	COG0515	serine threonine protein kinase
IAG44_RS31795	COG1595	DNA-templated transcription, initiation
IAG44_RS31830	COG2188	Transcriptional regulator
IAG44_RS31835	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
IAG44_RS31845	COG1309	transcriptional regulator
IAG44_RS31850	COG3383	formate dehydrogenase (NAD+) activity
IAG44_RS31855	COG2851	Citrate transporter
IAG44_RS31865	COG3842	ATPase activity
IAG44_RS31870	COG0477	Major facilitator Superfamily
IAG44_RS31880	COG1960	acyl-CoA dehydrogenase activity
IAG44_RS31900	COG0789	Transcriptional regulator
IAG44_RS31930	COG1028	Short-chain dehydrogenase reductase Sdr
IAG44_RS31935	COG0318	PFAM AMP-dependent synthetase and ligase
IAG44_RS31970	COG2149	membrane
IAG44_RS31980	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
IAG44_RS32005	COG1063	alcohol dehydrogenase
IAG44_RS32010	COG1028	Short-chain dehydrogenase reductase Sdr
IAG44_RS32020	COG3265	gluconokinase activity
IAG44_RS32025	COG2186	Transcriptional regulator
IAG44_RS32030	COG3012	SEC-C Motif Domain Protein
IAG44_RS32035	COG0308	aminopeptidase N
IAG44_RS32080	COG0667	Aldo Keto reductase
IAG44_RS32085	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAG44_RS32110	COG0215	cysteine-tRNA ligase activity
IAG44_RS32125	COG2186	Transcriptional regulator
IAG44_RS32130	COG0402	S-adenosylhomocysteine deaminase activity
IAG44_RS32140	COG1079	Belongs to the binding-protein-dependent transport system permease family
IAG44_RS32145	COG4603	Belongs to the binding-protein-dependent transport system permease family
IAG44_RS32150	COG3845	ABC transporter
IAG44_RS32160	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
IAG44_RS32160	COG0235	Class ii aldolase
IAG44_RS32165	COG0235	Class ii aldolase
IAG44_RS32170	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
IAG44_RS32175	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
IAG44_RS32185	COG1129	ABC transporter
IAG44_RS32195	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
IAG44_RS32200	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IAG44_RS32205	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IAG44_RS32210	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IAG44_RS32215	COG1414	Transcriptional regulator
IAG44_RS32225	COG0646	methionine synthase
IAG44_RS32225	COG1410	methionine synthase
IAG44_RS32235	COG0747	negative chemotaxis
IAG44_RS32240	COG2197	response regulator
IAG44_RS32250	COG1994	Peptidase M50
IAG44_RS32250	COG0517	IMP dehydrogenase activity
IAG44_RS32270	COG1222	aaa ATPase
IAG44_RS32275	COG4122	O-methyltransferase activity
IAG44_RS32290	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
IAG44_RS32295	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
IAG44_RS32300	COG1609	Transcriptional regulator
IAG44_RS32310	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
IAG44_RS32315	COG0545	Peptidyl-prolyl cis-trans isomerase
IAG44_RS32345	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IAG44_RS32350	COG0805	protein transport
IAG44_RS32405	COG1309	transcriptional regulator
IAG44_RS32410	COG0564	pseudouridine synthase activity
IAG44_RS32430	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IAG44_RS32435	COG0517	IMP dehydrogenase activity
IAG44_RS32435	COG4175	Glycine betaine
IAG44_RS32440	COG4176	ABC-type proline glycine betaine transport system permease component
IAG44_RS32455	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IAG44_RS32460	COG2186	Transcriptional regulator
IAG44_RS32465	COG0174	glutamine synthetase
IAG44_RS32470	COG1012	belongs to the aldehyde dehydrogenase family
IAG44_RS32510	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IAG44_RS32515	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IAG44_RS32520	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IAG44_RS32525	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IAG44_RS32530	COG5002	protein histidine kinase activity
IAG44_RS32535	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IAG44_RS32540	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IAG44_RS32540	COG0072	phenylalanine-tRNA ligase activity
IAG44_RS32570	COG1649	PFAM Uncharacterised BCR, COG1649
IAG44_RS32580	COG0697	spore germination
IAG44_RS32585	COG1609	Transcriptional regulator
IAG44_RS32625	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IAG44_RS32630	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IAG44_RS32635	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IAG44_RS32640	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IAG44_RS32645	COG1438	arginine binding
IAG44_RS32660	COG1017	nitric oxide dioxygenase activity
IAG44_RS32660	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IAG44_RS32675	COG0326	Molecular chaperone. Has ATPase activity
IAG44_RS32680	COG0165	Argininosuccinate lyase
IAG44_RS32685	COG0137	argininosuccinate synthase activity
IAG44_RS32730	COG0477	Major facilitator Superfamily
IAG44_RS32740	COG0584	glycerophosphoryl diester phosphodiesterase
IAG44_RS32760	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IAG44_RS32765	COG2011	ABC-type metal ion transport system permease component
IAG44_RS32770	COG1464	Belongs to the NlpA lipoprotein family
IAG44_RS32790	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
IAG44_RS32795	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IAG44_RS32795	COG1648	precorrin-2 dehydrogenase activity
IAG44_RS32855	COG0512	Glutamine amidotransferase of anthranilate synthase
IAG44_RS32855	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IAG44_RS32915	COG1175	transmembrane transport
IAG44_RS32920	COG0395	ABC-type sugar transport system, permease component
IAG44_RS32945	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IAG44_RS32960	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IAG44_RS32980	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IAG44_RS32985	COG1560	Kdo2-lipid A biosynthetic process
IAG44_RS32990	COG0438	transferase activity, transferring glycosyl groups
IAG44_RS33005	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
IAG44_RS33010	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
IAG44_RS33015	COG0217	transcriptional regulatory protein
IAG44_RS33020	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
IAG44_RS33025	COG0632	four-way junction helicase activity
IAG44_RS33030	COG2255	four-way junction helicase activity
IAG44_RS33040	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IAG44_RS33045	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IAG44_RS33050	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IAG44_RS33055	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IAG44_RS33060	COG1196	nuclear chromosome segregation
IAG44_RS33065	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IAG44_RS33075	COG0124	histidyl-tRNA synthetase
IAG44_RS33090	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IAG44_RS33105	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IAG44_RS33110	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IAG44_RS33120	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IAG44_RS33130	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IAG44_RS33135	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IAG44_RS33140	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IAG44_RS33150	COG0006	proline dipeptidase activity
IAG44_RS33155	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IAG44_RS33160	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IAG44_RS33170	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IAG44_RS33175	COG0540	Belongs to the ATCase OTCase family
IAG44_RS33180	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IAG44_RS33190	COG0505	Belongs to the CarA family
IAG44_RS33195	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IAG44_RS33200	COG0167	dihydroorotate dehydrogenase activity
IAG44_RS33205	COG0284	orotidine-5'-phosphate decarboxylase activity
IAG44_RS33215	COG0194	GDP metabolic process
IAG44_RS33220	COG1758	RNA polymerase activity
IAG44_RS33230	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IAG44_RS33250	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IAG44_RS33260	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IAG44_RS33265	COG2390	Transcriptional regulator
IAG44_RS33295	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IAG44_RS33310	COG2223	nitrite transmembrane transporter activity
IAG44_RS33325	COG1090	epimerase
IAG44_RS33340	COG3201	nicotinamide mononucleotide transporter
IAG44_RS33345	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IAG44_RS33345	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IAG44_RS33350	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
IAG44_RS33355	COG0140	phosphoribosyl-ATP diphosphatase activity
IAG44_RS33360	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IAG44_RS33425	COG1216	Glycosyl transferase, family 2
IAG44_RS33440	COG2270	Major facilitator Superfamily
IAG44_RS33490	COG2755	lipolytic protein G-D-S-L family
IAG44_RS33495	COG1984	allophanate hydrolase subunit 2
IAG44_RS33500	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
IAG44_RS33505	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
IAG44_RS33510	COG4336	lyase activity
IAG44_RS33550	COG2018	Roadblock/LC7 domain
IAG44_RS33565	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IAG44_RS33580	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
IAG44_RS33595	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IAG44_RS33600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IAG44_RS33615	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IAG44_RS33645	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IAG44_RS33665	COG1716	ATPase activity
IAG44_RS33685	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IAG44_RS33695	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IAG44_RS33695	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IAG44_RS33710	COG0725	ABC transporter, periplasmic molybdate-binding protein
IAG44_RS33725	COG1653	transport
IAG44_RS33730	COG1175	transmembrane transport
IAG44_RS33735	COG0395	ABC-type sugar transport system, permease component
IAG44_RS33745	COG1609	Transcriptional regulator
IAG44_RS33770	COG0384	phenazine biosynthesis protein PhzF
IAG44_RS33780	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IAG44_RS33785	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IAG44_RS33860	COG0747	negative chemotaxis
IAG44_RS33865	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IAG44_RS33880	COG1028	Short-chain dehydrogenase reductase Sdr
IAG44_RS33895	COG0815	Transfers the fatty acyl group on membrane lipoproteins
IAG44_RS33900	COG0673	inositol 2-dehydrogenase activity
IAG44_RS33915	COG2318	DinB family
IAG44_RS33940	COG1968	undecaprenyl-diphosphatase activity
IAG44_RS33970	COG0183	Belongs to the thiolase family
IAG44_RS33980	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IAG44_RS34010	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IAG44_RS34035	COG0110	maltose O-acetyltransferase activity
IAG44_RS34055	COG0640	Transcriptional regulator
IAG44_RS34065	COG1832	CoA-binding protein
IAG44_RS34080	COG1739	Uncharacterized protein family UPF0029
IAG44_RS34085	COG0420	3'-5' exonuclease activity
IAG44_RS34090	COG0419	ATPase involved in DNA repair
IAG44_RS34095	COG1522	sequence-specific DNA binding
IAG44_RS34125	COG2188	Transcriptional regulator
IAG44_RS34130	COG1940	carbohydrate kinase activity
IAG44_RS34135	COG2197	response regulator
IAG44_RS34140	COG4585	Histidine kinase
IAG44_RS34155	COG3663	DNA glycosylase
IAG44_RS34160	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IAG44_RS34180	COG0456	acetyltransferase
IAG44_RS34190	COG2226	methyltransferase
IAG44_RS34205	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IAG44_RS34210	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IAG44_RS34215	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IAG44_RS34240	COG0741	lytic transglycosylase activity
IAG44_RS34240	COG0791	NLP P60 protein
IAG44_RS34250	COG0740	serine-type endopeptidase activity
IAG44_RS34265	COG1309	transcriptional regulator
IAG44_RS34270	COG0831	urea catabolic process
IAG44_RS34275	COG0832	Belongs to the urease beta subunit family
IAG44_RS34280	COG0804	urea catabolic process
IAG44_RS34285	COG0830	nickel cation binding
IAG44_RS34290	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
IAG44_RS34295	COG0829	nickel cation binding
IAG44_RS34305	COG0204	Acyl-transferase
IAG44_RS34310	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IAG44_RS34315	COG1834	amidinotransferase
IAG44_RS34320	COG1522	sequence-specific DNA binding
IAG44_RS34325	COG3279	Response regulator of the LytR AlgR family
IAG44_RS34340	COG3275	phosphorelay sensor kinase activity
IAG44_RS34355	COG0205	6-phosphofructokinase activity
IAG44_RS34360	COG3442	glutamine amidotransferase
IAG44_RS34370	COG0242	peptide deformylase activity
IAG44_RS34380	COG1960	acyl-CoA dehydrogenase activity
IAG44_RS34390	COG2124	cytochrome p450
IAG44_RS34395	COG3424	synthase
IAG44_RS34400	COG1252	NADH dehydrogenase
IAG44_RS34420	COG1793	dna ligase
IAG44_RS34435	COG1960	acyl-CoA dehydrogenase activity
IAG44_RS34440	COG1960	acyl-CoA dehydrogenase activity
IAG44_RS34460	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IAG44_RS34465	COG2409	Drug exporters of the RND superfamily
IAG44_RS34470	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IAG44_RS34510	COG2272	Belongs to the type-B carboxylesterase lipase family
IAG44_RS34515	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IAG44_RS34525	COG1063	alcohol dehydrogenase
IAG44_RS34545	COG1472	Belongs to the glycosyl hydrolase 3 family
IAG44_RS34555	COG1175	transmembrane transport
IAG44_RS34565	COG1609	Transcriptional regulator
IAG44_RS34570	COG1012	belongs to the aldehyde dehydrogenase family
IAG44_RS34585	COG1940	carbohydrate kinase activity
IAG44_RS34585	COG1846	Transcriptional regulator
IAG44_RS34590	COG1070	Carbohydrate kinase
IAG44_RS34605	COG4279	zinc finger
IAG44_RS34610	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IAG44_RS34665	COG2018	Roadblock/LC7 domain
IAG44_RS34675	COG1946	Acyl-CoA thioesterase
IAG44_RS34690	COG0254	rRNA binding
IAG44_RS34700	COG1132	(ABC) transporter
IAG44_RS34720	COG1301	dicarboxylic acid transport
IAG44_RS34730	COG1132	(ABC) transporter
IAG44_RS34745	COG1116	anion transmembrane transporter activity
IAG44_RS34750	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IAG44_RS34755	COG0432	Pfam Uncharacterised protein family UPF0047
IAG44_RS34770	COG2814	Major facilitator Superfamily
IAG44_RS34775	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IAG44_RS34795	COG0438	transferase activity, transferring glycosyl groups
IAG44_RS34825	COG1846	Transcriptional regulator
IAG44_RS34835	COG4585	Histidine kinase
IAG44_RS34870	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IAG44_RS34880	COG0765	amino acid transport
IAG44_RS34885	COG1126	abc transporter atp-binding protein
IAG44_RS34890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IAG44_RS34900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAG44_RS34905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAG44_RS34915	COG2197	response regulator
IAG44_RS34940	COG2124	cytochrome p450
IAG44_RS34955	COG2838	Isocitrate dehydrogenase
IAG44_RS34960	COG0668	transmembrane transport
IAG44_RS34970	COG1132	(ABC) transporter
IAG44_RS34995	COG1309	transcriptional regulator
IAG44_RS35020	COG1652	LysM domain
IAG44_RS35035	COG0297	glycogen (starch) synthase activity
IAG44_RS35040	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IAG44_RS35060	COG1028	Short-chain dehydrogenase reductase Sdr
IAG44_RS35075	COG0454	-acetyltransferase
IAG44_RS35075	COG0456	acetyltransferase
IAG44_RS35090	COG0154	amidase activity
IAG44_RS35115	COG2186	Transcriptional regulator
IAG44_RS35120	COG4948	Mandelate Racemase Muconate Lactonizing
IAG44_RS35125	COG1028	Short-chain dehydrogenase reductase Sdr
IAG44_RS35140	COG3618	amidohydrolase
IAG44_RS35155	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IAG44_RS35185	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IAG44_RS35185	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IAG44_RS35190	COG0726	polysaccharide deacetylase
IAG44_RS35230	COG0583	DNA-binding transcription factor activity
IAG44_RS35240	COG1053	succinate dehydrogenase
IAG44_RS35245	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IAG44_RS35265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAG44_RS35270	COG1522	sequence-specific DNA binding
IAG44_RS35275	COG1280	lysine exporter protein (LysE YggA)
IAG44_RS35280	COG0523	cobalamin synthesis protein
IAG44_RS35300	COG3360	Dodecin
IAG44_RS35305	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
IAG44_RS35310	COG0121	glutamine amidotransferase
IAG44_RS35320	COG3572	ergothioneine biosynthetic process
IAG44_RS35370	COG0477	Major facilitator Superfamily
IAG44_RS35400	COG1012	belongs to the aldehyde dehydrogenase family
IAG44_RS35410	COG4585	Histidine kinase
IAG44_RS35415	COG2197	response regulator
IAG44_RS35425	COG0745	RESPONSE REGULATOR receiver
IAG44_RS35440	COG0124	histidyl-tRNA synthetase
IAG44_RS35445	COG1280	lysine exporter protein (LysE YggA)
IAG44_RS35460	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IAG44_RS35465	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IAG44_RS35470	COG0655	NAD(P)H dehydrogenase (quinone) activity
IAG44_RS35475	COG0318	PFAM AMP-dependent synthetase and ligase
IAG44_RS35485	COG1250	3-hydroxyacyl-CoA dehydrogenase
IAG44_RS35495	COG1960	acyl-CoA dehydrogenase activity
IAG44_RS35510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IAG44_RS35525	COG0318	PFAM AMP-dependent synthetase and ligase
IAG44_RS35550	COG0402	S-adenosylhomocysteine deaminase activity
IAG44_RS35560	COG2124	cytochrome p450
IAG44_RS35570	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IAG44_RS35585	COG1116	anion transmembrane transporter activity
IAG44_RS35590	COG0640	Transcriptional regulator
IAG44_RS35595	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IAG44_RS35600	COG0477	Major facilitator Superfamily
IAG44_RS35605	COG0745	RESPONSE REGULATOR receiver
IAG44_RS35620	COG1124	(ABC) transporter
IAG44_RS35625	COG0444	Belongs to the ABC transporter superfamily
IAG44_RS35630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAG44_RS35635	COG0601	transmembrane transport
IAG44_RS35655	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IAG44_RS35660	COG1609	Transcriptional regulator
IAG44_RS35675	COG0395	ABC-type sugar transport system, permease component
IAG44_RS35690	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IAG44_RS35715	COG2755	lipolytic protein G-D-S-L family
IAG44_RS35720	COG1082	Xylose isomerase domain protein TIM barrel
IAG44_RS35725	COG0673	inositol 2-dehydrogenase activity
IAG44_RS35730	COG2814	Major facilitator Superfamily
IAG44_RS35735	COG1609	Transcriptional regulator
IAG44_RS35760	COG2890	protein-(glutamine-N5) methyltransferase activity
IAG44_RS35815	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IAG44_RS35820	COG2814	Major facilitator Superfamily
IAG44_RS35840	COG0673	inositol 2-dehydrogenase activity
IAG44_RS35860	COG2409	Drug exporters of the RND superfamily
IAG44_RS35870	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IAG44_RS35875	COG0318	PFAM AMP-dependent synthetase and ligase
IAG44_RS35890	COG1120	ATPase activity
IAG44_RS35895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAG44_RS35920	COG2814	Major facilitator Superfamily
IAG44_RS35925	COG2197	response regulator
IAG44_RS35955	COG3973	AAA domain
IAG44_RS35960	COG1819	glycosyl
IAG44_RS35965	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAG44_RS35980	COG1609	Transcriptional regulator
IAG44_RS35990	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IAG44_RS36000	COG0242	peptide deformylase activity
IAG44_RS36090	COG0745	RESPONSE REGULATOR receiver
IAG44_RS36095	COG2205	protein histidine kinase activity
IAG44_RS36100	COG0300	oxidoreductase activity
IAG44_RS36115	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IAG44_RS36120	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IAG44_RS36125	COG0179	Fumarylacetoacetate (FAA) hydrolase
IAG44_RS36150	COG0477	Major facilitator Superfamily
IAG44_RS36155	COG0515	serine threonine protein kinase
IAG44_RS36165	COG0753	catalase activity
IAG44_RS36180	COG0028	Belongs to the TPP enzyme family
IAG44_RS36185	COG0247	lactate metabolic process
IAG44_RS36185	COG0277	FAD linked oxidase domain protein
IAG44_RS36190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAG44_RS36230	COG1006	Multisubunit Na H antiporter MnhC subunit
IAG44_RS36235	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IAG44_RS36240	COG0248	Ppx GppA phosphatase
IAG44_RS36300	COG1793	dna ligase
IAG44_RS36300	COG3285	dna ligase
IAG44_RS36320	COG0720	synthase
IAG44_RS36330	COG0302	gtp cyclohydrolase
IAG44_RS36350	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IAG44_RS36360	COG2226	methyltransferase
IAG44_RS36380	COG3958	Transketolase
IAG44_RS36405	COG2764	glyoxalase bleomycin resistance protein dioxygenase
IAG44_RS36410	COG1012	belongs to the aldehyde dehydrogenase family
IAG44_RS36425	COG1028	Short-chain dehydrogenase reductase Sdr
IAG44_RS36490	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IAG44_RS36490	COG0515	serine threonine protein kinase
IAG44_RS36545	COG0542	response to heat
IAG44_RS36550	COG1556	Lactate utilization protein
IAG44_RS36555	COG1139	Iron-sulfur cluster binding protein
IAG44_RS36560	COG0247	lactate metabolic process
IAG44_RS36565	COG1070	Carbohydrate kinase
IAG44_RS36570	COG1028	Short-chain dehydrogenase reductase Sdr
IAG44_RS36570	COG3347	Dehydrogenase
IAG44_RS36580	COG1129	ABC transporter
IAG44_RS36590	COG1172	Belongs to the binding-protein-dependent transport system permease family
IAG44_RS36595	COG1879	ABC-type sugar transport system periplasmic component
IAG44_RS36610	COG1609	Transcriptional regulator
IAG44_RS36620	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IAG44_RS36625	COG1595	DNA-templated transcription, initiation
IAG44_RS36630	COG1357	PFAM Pentapeptide repeats (8 copies)
IAG44_RS36640	COG1309	transcriptional regulator
IAG44_RS36650	COG2706	6-phosphogluconolactonase activity
IAG44_RS36715	COG3467	pyridoxamine 5'-phosphate
IAG44_RS36735	COG2197	response regulator
IAG44_RS36740	COG4585	Histidine kinase
IAG44_RS36745	COG2267	carboxylic ester hydrolase activity
IAG44_RS36750	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IAG44_RS36765	COG1846	Transcriptional regulator
IAG44_RS36770	COG1012	belongs to the aldehyde dehydrogenase family
IAG44_RS36795	COG2124	cytochrome p450
IAG44_RS36810	COG0667	Aldo Keto reductase
IAG44_RS36830	COG0574	Belongs to the PEP-utilizing enzyme family
IAG44_RS36830	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IAG44_RS36845	COG4585	Histidine kinase
IAG44_RS36850	COG2197	response regulator
IAG44_RS36880	COG3250	beta-galactosidase activity
IAG44_RS36935	COG2197	response regulator
IAG44_RS36970	COG2197	response regulator
IAG44_RS36975	COG1132	(ABC) transporter
IAG44_RS36980	COG1132	(ABC) transporter
IAG44_RS36990	COG0515	serine threonine protein kinase
IAG44_RS37000	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
IAG44_RS37035	COG0019	diaminopimelate decarboxylase activity
IAG44_RS37040	COG4264	IucA IucC family
IAG44_RS37045	COG2814	Major facilitator Superfamily
IAG44_RS37055	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IAG44_RS37060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IAG44_RS37065	COG1120	ATPase activity
IAG44_RS37070	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAG44_RS37075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAG44_RS37085	COG1132	(ABC) transporter
IAG44_RS37095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IAG44_RS37100	COG1028	Short-chain dehydrogenase reductase Sdr
IAG44_RS37130	COG1653	transport
IAG44_RS37135	COG1175	transmembrane transport
IAG44_RS37140	COG0395	ABC-type sugar transport system, permease component
IAG44_RS37145	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IAG44_RS37150	COG4948	Mandelate Racemase Muconate Lactonizing
IAG44_RS37175	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IAG44_RS37230	COG1175	transmembrane transport
IAG44_RS37235	COG0395	ABC-type sugar transport system, permease component
IAG44_RS37270	COG2814	Major facilitator Superfamily
IAG44_RS37285	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
IAG44_RS37330	COG0673	inositol 2-dehydrogenase activity
IAG44_RS37435	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IAG44_RS37455	COG3552	Protein containing von Willebrand factor type A (VWA) domain
IAG44_RS37460	COG0714	Associated with various cellular activities
IAG44_RS37470	COG0596	Alpha beta hydrolase
IAG44_RS37490	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IAG44_RS37500	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAG44_RS37505	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
IAG44_RS37555	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IAG44_RS37560	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAG44_RS37565	COG0601	transmembrane transport
IAG44_RS37585	COG4948	Mandelate Racemase Muconate Lactonizing
IAG44_RS37590	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IAG44_RS37600	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IAG44_RS37615	COG1472	Belongs to the glycosyl hydrolase 3 family
IAG44_RS37625	COG2971	BadF BadG BcrA BcrD
IAG44_RS37630	COG1472	Belongs to the glycosyl hydrolase 3 family
IAG44_RS37635	COG0395	ABC-type sugar transport system, permease component
IAG44_RS37640	COG1175	transmembrane transport
IAG44_RS37660	COG1737	Transcriptional regulator
IAG44_RS37665	COG4821	SIS domain
IAG44_RS37670	COG3525	Glycosyl hydrolase, family 20, catalytic domain
IAG44_RS37675	COG2353	YceI-like domain
IAG44_RS37685	COG3485	protocatechuate 3,4-dioxygenase
IAG44_RS37695	COG3284	Transcriptional regulator
IAG44_RS37705	COG4932	domain protein
IAG44_RS37760	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IAG44_RS37775	COG3833	ABC-type maltose transport systems, permease component
IAG44_RS37780	COG1175	transmembrane transport
IAG44_RS37855	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IAG44_RS37870	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
IAG44_RS37885	COG1012	belongs to the aldehyde dehydrogenase family
IAG44_RS37890	COG4175	Glycine betaine
IAG44_RS37890	COG0517	IMP dehydrogenase activity
IAG44_RS37895	COG4176	ABC-type proline glycine betaine transport system permease component
IAG44_RS37910	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IAG44_RS37915	COG0367	asparagine synthase
IAG44_RS37940	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IAG44_RS37950	COG4585	Histidine kinase
IAG44_RS37960	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IAG44_RS37965	COG2226	methyltransferase
IAG44_RS37965	COG2867	negative regulation of translational initiation
IAG44_RS37975	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IAG44_RS38020	COG0825	malonyl-CoA metabolic process
IAG44_RS38020	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IAG44_RS38025	COG0511	ligase activity, forming carbon-carbon bonds
IAG44_RS38030	COG0439	Biotin carboxylase
IAG44_RS38040	COG2409	Drug exporters of the RND superfamily
IAG44_RS38045	COG2197	response regulator
IAG44_RS38055	COG2015	COG2015, Alkyl sulfatase and related hydrolases
IAG44_RS38090	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IAG44_RS38100	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IAG44_RS38115	COG2267	carboxylic ester hydrolase activity
IAG44_RS38120	COG1902	pentaerythritol trinitrate reductase activity
IAG44_RS38155	COG3118	belongs to the thioredoxin family
IAG44_RS38160	COG2015	COG2015, Alkyl sulfatase and related hydrolases
IAG44_RS38165	COG1285	pathogenesis
IAG44_RS38180	COG0076	glutamate decarboxylase activity
IAG44_RS38200	COG3629	intracellular signal transduction
IAG44_RS38200	COG3903	Transcriptional regulator
IAG44_RS38210	COG1408	metallophosphoesterase
IAG44_RS38220	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IAG44_RS38235	COG0142	geranyltranstransferase activity
IAG44_RS38240	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IAG44_RS38265	COG3425	synthase
IAG44_RS38285	COG4585	Histidine kinase
IAG44_RS38290	COG2409	Drug exporters of the RND superfamily
IAG44_RS38310	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IAG44_RS38320	COG2197	response regulator
IAG44_RS38330	COG2132	Multicopper oxidase
IAG44_RS38345	COG0527	aspartate kinase activity
IAG44_RS38365	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
IAG44_RS38370	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IAG44_RS38375	COG1028	Short-chain dehydrogenase reductase Sdr
IAG44_RS38395	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IAG44_RS38410	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IAG44_RS38440	COG3507	Belongs to the glycosyl hydrolase 43 family
IAG44_RS38460	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IAG44_RS38465	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
IAG44_RS38470	COG0803	Belongs to the bacterial solute-binding protein 9 family
IAG44_RS38490	COG2311	Membrane
IAG44_RS38500	COG1280	lysine exporter protein (LysE YggA)
IAG44_RS38510	COG1028	Short-chain dehydrogenase reductase Sdr
IAG44_RS38520	COG1621	beta-fructofuranosidase activity
IAG44_RS38545	COG1609	Transcriptional regulator
IAG44_RS38560	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IAG44_RS38570	COG1733	regulation of RNA biosynthetic process
IAG44_RS38575	COG0596	Alpha beta hydrolase
IAG44_RS38580	COG2272	Belongs to the type-B carboxylesterase lipase family
IAG44_RS38585	COG1063	alcohol dehydrogenase
IAG44_RS38595	COG2315	Protein conserved in bacteria
IAG44_RS38600	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IAG44_RS38615	COG0714	Associated with various cellular activities
IAG44_RS38660	COG0477	Major facilitator Superfamily
IAG44_RS38670	COG1132	(ABC) transporter
IAG44_RS38670	COG2375	cellular response to nickel ion
IAG44_RS38675	COG1132	(ABC) transporter
IAG44_RS38705	COG3433	isochorismatase activity
IAG44_RS38705	COG2226	methyltransferase
IAG44_RS38705	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IAG44_RS38710	COG2226	methyltransferase
IAG44_RS38710	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IAG44_RS38710	COG3433	isochorismatase activity
IAG44_RS38715	COG1021	2,3-dihydroxybenzoate-AMP ligase
IAG44_RS38720	COG1169	isochorismate synthase
IAG44_RS38755	COG0142	geranyltranstransferase activity
IAG44_RS38760	COG1562	ergosterol biosynthetic process
IAG44_RS38770	COG1131	(ABC) transporter
IAG44_RS38795	COG2226	methyltransferase
IAG44_RS38820	COG2226	methyltransferase
IAG44_RS38830	COG0546	phosphoglycolate phosphatase activity
IAG44_RS38845	COG1175	transmembrane transport
IAG44_RS38850	COG0395	ABC-type sugar transport system, permease component
IAG44_RS38870	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IAG44_RS38885	COG2345	Transcriptional regulator
IAG44_RS38945	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IAG44_RS38960	COG0174	glutamine synthetase
IAG44_RS38975	COG4689	acetoacetate decarboxylase
IAG44_RS38980	COG1012	belongs to the aldehyde dehydrogenase family
IAG44_RS38990	COG0179	Fumarylacetoacetate (FAA) hydrolase
IAG44_RS39005	COG1012	belongs to the aldehyde dehydrogenase family
IAG44_RS39010	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IAG44_RS39015	COG1846	Transcriptional regulator
IAG44_RS39045	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IAG44_RS39090	COG3321	synthase
IAG44_RS39090	COG0604	alcohol dehydrogenase
IAG44_RS39155	COG2124	cytochrome p450
IAG44_RS39165	COG3903	Transcriptional regulator
IAG44_RS39165	COG3629	intracellular signal transduction
IAG44_RS39255	COG2755	lipolytic protein G-D-S-L family
IAG44_RS39270	COG3401	FG-GAP repeat protein
IAG44_RS39370	COG0789	Transcriptional regulator
IAG44_RS39375	COG0300	oxidoreductase activity
IAG44_RS39380	COG2197	response regulator
IAG44_RS39385	COG0604	alcohol dehydrogenase
IAG44_RS39385	COG1028	Short-chain dehydrogenase reductase Sdr
IAG44_RS39385	COG3321	synthase
IAG44_RS39410	COG0587	DNA-directed DNA polymerase activity
IAG44_RS39415	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IAG44_RS39415	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IAG44_RS39425	COG1132	(ABC) transporter
IAG44_RS39450	COG1802	Transcriptional regulator
IAG44_RS39460	COG3842	ATPase activity
IAG44_RS39480	COG1250	3-hydroxyacyl-CoA dehydrogenase
IAG44_RS39480	COG1024	Enoyl-CoA hydratase
IAG44_RS39500	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IAG44_RS39510	COG3618	amidohydrolase
IAG44_RS39525	COG0730	response to heat
IAG44_RS39530	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IAG44_RS39535	COG1937	Protein conserved in bacteria
IAG44_RS39555	COG0659	secondary active sulfate transmembrane transporter activity
IAG44_RS39560	COG0789	Transcriptional regulator
IAG44_RS39580	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
IAG44_RS39585	COG1181	Belongs to the D-alanine--D-alanine ligase family
IAG44_RS39595	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IAG44_RS39610	COG2205	protein histidine kinase activity
IAG44_RS39635	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IAG44_RS39655	COG1088	dTDP-glucose 4,6-dehydratase activity
IAG44_RS39680	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IAG44_RS39685	COG1104	cysteine desulfurase activity
IAG44_RS39690	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IAG44_RS39785	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IAG44_RS39805	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IAG44_RS39830	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IAG44_RS39940	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IAG44_RS40060	COG0791	NLP P60 protein
IAG44_RS40125	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IAG44_RS40130	COG1819	glycosyl
IAG44_RS40135	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IAG44_RS40140	COG1309	transcriptional regulator
IAG44_RS40155	COG0300	oxidoreductase activity
IAG44_RS40155	COG0318	PFAM AMP-dependent synthetase and ligase
IAG44_RS40155	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IAG44_RS40155	COG3321	synthase
IAG44_RS40155	COG1028	Short-chain dehydrogenase reductase Sdr
IAG44_RS40160	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IAG44_RS40160	COG4221	oxidoreductase activity
IAG44_RS40160	COG3321	synthase
IAG44_RS40160	COG1028	Short-chain dehydrogenase reductase Sdr
IAG44_RS40180	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IAG44_RS40210	COG0126	phosphoglycerate kinase activity
IAG44_RS40215	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IAG44_RS40220	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IAG44_RS40230	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IAG44_RS40260	COG0583	DNA-binding transcription factor activity
IAG44_RS40320	COG1620	l-lactate permease
IAG44_RS40355	COG0477	Major facilitator Superfamily
IAG44_RS40450	COG1309	transcriptional regulator
IAG44_RS40465	COG0667	Aldo Keto reductase
IAG44_RS40505	COG1028	Short-chain dehydrogenase reductase Sdr
IAG44_RS40510	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IAG44_RS40520	COG2188	Transcriptional regulator
IAG44_RS40585	COG5297	Belongs to the glycosyl hydrolase family 6
IAG44_RS40585	COG4733	cellulase activity
IAG44_RS40590	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAG44_RS40595	COG0431	NADPH-dependent FMN reductase
IAG44_RS40600	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IAG44_RS40615	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IAG44_RS40625	COG1024	Enoyl-CoA hydratase
IAG44_RS40630	COG1024	Enoyl-CoA hydratase
IAG44_RS40645	COG3251	PFAM MbtH domain protein
IAG44_RS40675	COG3629	intracellular signal transduction
IAG44_RS40745	COG0515	serine threonine protein kinase
IAG44_RS40745	COG2815	serine threonine protein kinase
IAG44_RS40775	COG1620	l-lactate permease
IAG44_RS40800	COG1309	transcriptional regulator
IAG44_RS40835	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IAG44_RS40920	COG0076	glutamate decarboxylase activity
IAG44_RS40935	COG0477	Major facilitator Superfamily
IAG44_RS40990	COG2814	Major facilitator Superfamily
IAG44_RS41000	COG2409	Drug exporters of the RND superfamily
IAG44_RS41025	COG2814	Major facilitator Superfamily
IAG44_RS41040	COG0583	DNA-binding transcription factor activity
IAG44_RS41050	COG1733	regulation of RNA biosynthetic process
IAG44_RS41055	COG0702	epimerase
IAG44_RS41070	COG4585	Histidine kinase
IAG44_RS41075	COG2197	response regulator
IAG44_RS41120	COG3833	ABC-type maltose transport systems, permease component
IAG44_RS41190	COG0583	DNA-binding transcription factor activity
IAG44_RS41210	COG3629	intracellular signal transduction
IAG44_RS41210	COG3903	Transcriptional regulator
IAG44_RS41215	COG0488	(ABC) transporter
IAG44_RS41235	COG0667	Aldo Keto reductase
IAG44_RS41285	COG3345	alpha-galactosidase
IAG44_RS41295	COG3795	YCII-related domain
IAG44_RS41305	COG3903	Transcriptional regulator
IAG44_RS41305	COG3629	intracellular signal transduction
IAG44_RS41325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IAG44_RS41340	COG3250	beta-galactosidase activity
IAG44_RS41350	COG2124	cytochrome p450
IAG44_RS41355	COG4221	oxidoreductase activity
IAG44_RS41365	COG0500	methyltransferase
IAG44_RS41375	COG1959	2 iron, 2 sulfur cluster binding
IAG44_RS41390	COG1028	Short-chain dehydrogenase reductase Sdr
IAG44_RS41400	COG1028	Short-chain dehydrogenase reductase Sdr
IAG44_RS41415	COG4770	biotin carboxylase activity
IAG44_RS41420	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IAG44_RS41435	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IAG44_RS41455	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IAG44_RS41460	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IAG44_RS41465	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAG44_RS41475	COG0431	NADPH-dependent FMN reductase
IAG44_RS41490	COG2828	Protein conserved in bacteria
IAG44_RS41520	COG4977	sequence-specific DNA binding
IAG44_RS41530	COG2814	Major facilitator Superfamily
IAG44_RS41575	COG1309	transcriptional regulator
IAG44_RS41580	COG2080	2 iron, 2 sulfur cluster binding
IAG44_RS41585	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
IAG44_RS41590	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IAG44_RS41715	COG1857	crispr-associated protein
IAG44_RS41730	COG1518	maintenance of DNA repeat elements
IAG44_RS41735	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IAG44_RS41745	COG1132	(ABC) transporter
IAG44_RS41780	COG1733	regulation of RNA biosynthetic process
IAG44_RS41825	COG1609	Transcriptional regulator
IAG44_RS41845	COG0395	ABC-type sugar transport system, permease component
IAG44_RS41850	COG4209	transmembrane transport
IAG44_RS41860	COG4214	carbohydrate transport
IAG44_RS41865	COG1129	ABC transporter
IAG44_RS41875	COG4948	Mandelate Racemase Muconate Lactonizing
IAG44_RS41880	COG3875	lactate racemase activity
IAG44_RS41885	COG1691	(AIR) carboxylase
IAG44_RS41890	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
IAG44_RS41895	COG1606	tRNA processing
IAG44_RS41910	COG0395	ABC-type sugar transport system, permease component
IAG44_RS41915	COG1175	transmembrane transport
IAG44_RS41925	COG2186	Transcriptional regulator
IAG44_RS41940	COG0745	RESPONSE REGULATOR receiver
IAG44_RS41950	COG0154	amidase activity
IAG44_RS41960	COG5520	Belongs to the glycosyl hydrolase 30 family
IAG44_RS41985	COG2319	Wd-40 repeat
IAG44_RS41985	COG4249	Peptidase C14 caspase catalytic subunit p20
IAG44_RS42040	COG0477	Major facilitator Superfamily
IAG44_RS42045	COG3959	Transketolase, thiamine diphosphate binding domain
IAG44_RS42050	COG3958	Transketolase
IAG44_RS42055	COG1028	Short-chain dehydrogenase reductase Sdr
IAG44_RS42060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAG44_RS42075	COG3185	4-Hydroxyphenylpyruvate dioxygenase
IAG44_RS42100	COG0561	phosphatase activity
IAG44_RS42105	COG4941	Belongs to the sigma-70 factor family
IAG44_RS42110	COG3795	YCII-related domain
IAG44_RS42115	COG3835	regulator
IAG44_RS42140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAG44_RS42175	COG1228	amidohydrolase
IAG44_RS42230	COG2318	DinB family
IAG44_RS42235	COG2409	Drug exporters of the RND superfamily
IAG44_RS42330	COG1982	Orn Lys Arg decarboxylase major
IAG44_RS42355	COG1228	amidohydrolase
IAG44_RS42385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IAG44_RS42390	COG2188	Transcriptional regulator
IAG44_RS42415	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
IAG44_RS42420	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
IAG44_RS42430	COG0535	radical SAM domain protein
IAG44_RS42470	COG0477	Major facilitator Superfamily
IAG44_RS42480	COG1959	2 iron, 2 sulfur cluster binding
IAG44_RS42515	COG4585	Histidine kinase
IAG44_RS42520	COG2197	response regulator
IAG44_RS42530	COG4565	transcriptional regulatory protein
IAG44_RS42535	COG3290	protein histidine kinase activity
IAG44_RS42575	COG3903	Transcriptional regulator
IAG44_RS42575	COG3629	intracellular signal transduction
IAG44_RS42595	COG0657	acetylesterase activity
IAG44_RS42640	COG0789	Transcriptional regulator
IAG44_RS42645	COG0604	alcohol dehydrogenase
IAG44_RS42655	COG0789	Transcriptional regulator
IAG44_RS42700	COG2909	trisaccharide binding
IAG44_RS42730	COG1764	response to oxidative stress
IAG44_RS42775	COG3903	Transcriptional regulator
IAG44_RS42775	COG3629	intracellular signal transduction
IAG44_RS42780	COG0596	Alpha beta hydrolase
IAG44_RS42800	COG1073	alpha beta
IAG44_RS42825	COG2267	carboxylic ester hydrolase activity
IAG44_RS42850	COG0596	Alpha beta hydrolase
IAG44_RS42860	COG0318	PFAM AMP-dependent synthetase and ligase
IAG44_RS42870	COG0154	amidase activity
IAG44_RS42880	COG1309	transcriptional regulator
IAG44_RS42900	COG0583	DNA-binding transcription factor activity