locus-tag	class	description
AS200_RS00100	COG3547	Transposase (IS116 IS110 IS902 family)
AS200_RS00110	COG0419	ATPase involved in DNA repair
AS200_RS00115	COG0420	3'-5' exonuclease activity
AS200_RS00140	COG3293	Transposase
AS200_RS00180	COG1191	sigma factor activity
AS200_RS00255	COG3547	Transposase (IS116 IS110 IS902 family)
AS200_RS00265	COG0758	DNA mediated transformation
AS200_RS00345	COG0515	serine threonine protein kinase
AS200_RS00345	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AS200_RS00420	COG0791	NLP P60 protein
AS200_RS00420	COG3883	PFAM NLP P60 protein
AS200_RS00560	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AS200_RS00600	COG0531	amino acid
AS200_RS00620	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AS200_RS00625	COG0583	DNA-binding transcription factor activity
AS200_RS00635	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AS200_RS00695	COG2197	response regulator
AS200_RS00710	COG1278	Cold shock
AS200_RS00730	COG3293	Transposase
AS200_RS00805	COG0546	phosphoglycolate phosphatase activity
AS200_RS00815	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AS200_RS00825	COG1278	Cold shock
AS200_RS00830	COG0513	Belongs to the DEAD box helicase family
AS200_RS00845	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AS200_RS00900	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS200_RS00905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS200_RS00920	COG0017	Asparaginyl-tRNA synthetase
AS200_RS00945	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AS200_RS01000	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AS200_RS01000	COG0301	tRNA thio-modification
AS200_RS01075	COG0667	Aldo Keto reductase
AS200_RS01090	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AS200_RS01095	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AS200_RS01100	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
AS200_RS01105	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AS200_RS01115	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS200_RS01125	COG0529	Catalyzes the synthesis of activated sulfate
AS200_RS01145	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AS200_RS01160	COG1132	(ABC) transporter
AS200_RS01185	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AS200_RS01215	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AS200_RS01225	COG1028	Short-chain dehydrogenase reductase Sdr
AS200_RS01240	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AS200_RS01260	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AS200_RS01270	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AS200_RS01305	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AS200_RS01325	COG4977	sequence-specific DNA binding
AS200_RS01340	COG3693	PFAM glycoside hydrolase, family 10
AS200_RS01340	COG3507	Belongs to the glycosyl hydrolase 43 family
AS200_RS01340	COG2382	esterase
AS200_RS01350	COG0745	RESPONSE REGULATOR receiver
AS200_RS01360	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AS200_RS01400	COG2015	COG2015, Alkyl sulfatase and related hydrolases
AS200_RS01460	COG2867	negative regulation of translational initiation
AS200_RS01480	COG2226	methyltransferase
AS200_RS01505	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AS200_RS01525	COG1252	NADH dehydrogenase
AS200_RS01530	COG1595	DNA-templated transcription, initiation
AS200_RS01540	COG3328	transposase activity
AS200_RS01565	COG0702	epimerase
AS200_RS01590	COG0789	Transcriptional regulator
AS200_RS01595	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AS200_RS01620	COG1937	Protein conserved in bacteria
AS200_RS01630	COG2226	methyltransferase
AS200_RS01640	COG0745	RESPONSE REGULATOR receiver
AS200_RS01660	COG0667	Aldo Keto reductase
AS200_RS01675	COG0656	L-ascorbic acid biosynthetic process
AS200_RS01680	COG1064	alcohol dehydrogenase
AS200_RS01690	COG0583	DNA-binding transcription factor activity
AS200_RS01695	COG0667	Aldo Keto reductase
AS200_RS01700	COG0667	Aldo Keto reductase
AS200_RS01725	COG3328	transposase activity
AS200_RS01730	COG0596	Alpha beta hydrolase
AS200_RS01765	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AS200_RS01785	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AS200_RS01805	COG0179	Fumarylacetoacetate (FAA) hydrolase
AS200_RS01830	COG1028	Short-chain dehydrogenase reductase Sdr
AS200_RS01845	COG0250	Participates in transcription elongation, termination and antitermination
AS200_RS01885	COG2186	Transcriptional regulator
AS200_RS01895	COG1175	transmembrane transport
AS200_RS01900	COG0395	ABC-type sugar transport system, permease component
AS200_RS01965	COG1191	sigma factor activity
AS200_RS01980	COG1028	Short-chain dehydrogenase reductase Sdr
AS200_RS02005	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AS200_RS02015	COG0567	Dehydrogenase, E1 component
AS200_RS02015	COG0508	dehydrogenase complex catalyzes the overall conversion of
AS200_RS02020	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AS200_RS02020	COG1017	nitric oxide dioxygenase activity
AS200_RS02035	COG2186	Transcriptional regulator
AS200_RS02050	COG0800	Aldolase
AS200_RS02055	COG1028	Short-chain dehydrogenase reductase Sdr
AS200_RS02060	COG1063	alcohol dehydrogenase
AS200_RS02070	COG3618	amidohydrolase
AS200_RS02075	COG4948	Mandelate Racemase Muconate Lactonizing
AS200_RS02080	COG1172	Belongs to the binding-protein-dependent transport system permease family
AS200_RS02135	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AS200_RS02140	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AS200_RS02185	COG1309	transcriptional regulator
AS200_RS02220	COG4221	oxidoreductase activity
AS200_RS02275	COG1404	Belongs to the peptidase S8 family
AS200_RS02280	COG0596	Alpha beta hydrolase
AS200_RS02285	COG3629	intracellular signal transduction
AS200_RS02285	COG3903	Transcriptional regulator
AS200_RS02300	COG0667	Aldo Keto reductase
AS200_RS02375	COG1597	lipid kinase activity
AS200_RS02380	COG0277	FAD linked oxidase domain protein
AS200_RS02445	COG0028	Belongs to the TPP enzyme family
AS200_RS02460	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AS200_RS02505	COG1090	epimerase
AS200_RS02570	COG0395	ABC-type sugar transport system, permease component
AS200_RS02575	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AS200_RS02585	COG2226	methyltransferase
AS200_RS02600	COG1733	regulation of RNA biosynthetic process
AS200_RS02620	COG0667	Aldo Keto reductase
AS200_RS02635	COG0151	Belongs to the GarS family
AS200_RS02640	COG0574	Belongs to the PEP-utilizing enzyme family
AS200_RS02640	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AS200_RS02655	COG1191	sigma factor activity
AS200_RS02665	COG2770	Histidine kinase
AS200_RS02665	COG2208	phosphoserine phosphatase activity
AS200_RS02670	COG1278	Cold shock
AS200_RS02675	COG0598	Magnesium transport protein CorA
AS200_RS02680	COG1295	ribonuclease BN
AS200_RS02735	COG0300	oxidoreductase activity
AS200_RS02735	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS200_RS02735	COG1028	Short-chain dehydrogenase reductase Sdr
AS200_RS02735	COG3321	synthase
AS200_RS02735	COG0318	PFAM AMP-dependent synthetase and ligase
AS200_RS02740	COG3321	synthase
AS200_RS02740	COG0300	oxidoreductase activity
AS200_RS02740	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AS200_RS02740	COG4221	oxidoreductase activity
AS200_RS02750	COG2814	Major facilitator Superfamily
AS200_RS02760	COG1181	Belongs to the D-alanine--D-alanine ligase family
AS200_RS02770	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AS200_RS02775	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AS200_RS02790	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AS200_RS02795	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AS200_RS02800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS200_RS02840	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AS200_RS02870	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AS200_RS02890	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AS200_RS02900	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS200_RS02930	COG4865	methylaspartate mutase activity
AS200_RS02945	COG1595	DNA-templated transcription, initiation
AS200_RS02960	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AS200_RS03040	COG2267	carboxylic ester hydrolase activity
AS200_RS03055	COG0402	S-adenosylhomocysteine deaminase activity
AS200_RS03060	COG1309	transcriptional regulator
AS200_RS03070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS200_RS03095	COG1175	transmembrane transport
AS200_RS03100	COG0395	ABC-type sugar transport system, permease component
AS200_RS03110	COG1028	Short-chain dehydrogenase reductase Sdr
AS200_RS03115	COG1309	transcriptional regulator
AS200_RS03155	COG1733	regulation of RNA biosynthetic process
AS200_RS03165	COG2135	peptidase activity
AS200_RS03180	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AS200_RS03210	COG0714	Associated with various cellular activities
AS200_RS03225	COG2124	cytochrome p450
AS200_RS03290	COG4335	DNA alkylation repair
AS200_RS03300	COG4221	oxidoreductase activity
AS200_RS03310	COG2197	response regulator
AS200_RS03325	COG1309	transcriptional regulator
AS200_RS03355	COG2186	Transcriptional regulator
AS200_RS03360	COG0129	dihydroxy-acid dehydratase activity
AS200_RS03370	COG1472	Belongs to the glycosyl hydrolase 3 family
AS200_RS03380	COG1175	transmembrane transport
AS200_RS03400	COG5520	Belongs to the glycosyl hydrolase 30 family
AS200_RS03405	COG0583	DNA-binding transcription factor activity
AS200_RS03410	COG0483	inositol monophosphate 1-phosphatase activity
AS200_RS03435	COG1366	Belongs to the anti-sigma-factor antagonist family
AS200_RS03475	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AS200_RS03485	COG2197	response regulator
AS200_RS03490	COG3851	Histidine kinase
AS200_RS03495	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AS200_RS03540	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AS200_RS03560	COG0438	transferase activity, transferring glycosyl groups
AS200_RS03570	COG0438	transferase activity, transferring glycosyl groups
AS200_RS03610	COG1028	Short-chain dehydrogenase reductase Sdr
AS200_RS03635	COG1012	belongs to the aldehyde dehydrogenase family
AS200_RS03640	COG1028	Short-chain dehydrogenase reductase Sdr
AS200_RS03645	COG2072	flavoprotein involved in K transport
AS200_RS03650	COG1595	DNA-templated transcription, initiation
AS200_RS03710	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AS200_RS03725	COG1028	Short-chain dehydrogenase reductase Sdr
AS200_RS03750	COG2267	carboxylic ester hydrolase activity
AS200_RS03755	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AS200_RS03800	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AS200_RS03820	COG3629	intracellular signal transduction
AS200_RS03820	COG3903	Transcriptional regulator
AS200_RS03850	COG0586	Pfam SNARE associated Golgi protein
AS200_RS03855	COG0076	glutamate decarboxylase activity
AS200_RS03900	COG0745	RESPONSE REGULATOR receiver
AS200_RS03905	COG2205	protein histidine kinase activity
AS200_RS03985	COG1595	DNA-templated transcription, initiation
AS200_RS04010	COG2197	response regulator
AS200_RS04015	COG4585	Histidine kinase
AS200_RS04020	COG0577	efflux transmembrane transporter activity
AS200_RS04020	COG1136	(ABC) transporter
AS200_RS04075	COG1959	2 iron, 2 sulfur cluster binding
AS200_RS04075	COG1295	ribonuclease BN
AS200_RS04100	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AS200_RS04120	COG1366	Belongs to the anti-sigma-factor antagonist family
AS200_RS04150	COG3629	intracellular signal transduction
AS200_RS04150	COG3903	Transcriptional regulator
AS200_RS04170	COG1028	Short-chain dehydrogenase reductase Sdr
AS200_RS04195	COG0640	Transcriptional regulator
AS200_RS04215	COG1028	Short-chain dehydrogenase reductase Sdr
AS200_RS04225	COG2124	cytochrome p450
AS200_RS04230	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AS200_RS04235	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AS200_RS04240	COG0179	Fumarylacetoacetate (FAA) hydrolase
AS200_RS04275	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AS200_RS04275	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AS200_RS04320	COG0464	growth
AS200_RS04340	COG1674	ftsk spoiiie
AS200_RS04345	COG2197	response regulator
AS200_RS04380	COG0671	phosphoesterase, PA-phosphatase related
AS200_RS04420	COG0179	Fumarylacetoacetate (FAA) hydrolase
AS200_RS04440	COG2319	Wd-40 repeat
AS200_RS04440	COG4249	Peptidase C14 caspase catalytic subunit p20
AS200_RS04470	COG0028	Belongs to the TPP enzyme family
AS200_RS04475	COG0069	glutamate synthase activity
AS200_RS04485	COG0789	Transcriptional regulator
AS200_RS04500	COG1366	Belongs to the anti-sigma-factor antagonist family
AS200_RS04540	COG3250	beta-galactosidase activity
AS200_RS04590	COG0596	Alpha beta hydrolase
AS200_RS04595	COG2208	phosphoserine phosphatase activity
AS200_RS04595	COG2770	Histidine kinase
AS200_RS04610	COG1902	pentaerythritol trinitrate reductase activity
AS200_RS04635	COG1366	Belongs to the anti-sigma-factor antagonist family
AS200_RS04640	COG1366	Belongs to the anti-sigma-factor antagonist family
AS200_RS04645	COG2172	sigma factor antagonist activity
AS200_RS04685	COG1132	(ABC) transporter
AS200_RS04690	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AS200_RS04695	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AS200_RS04700	COG2130	NADP-dependent
AS200_RS04770	COG3345	alpha-galactosidase
AS200_RS04815	COG0300	oxidoreductase activity
AS200_RS04830	COG0657	acetylesterase activity
AS200_RS04875	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AS200_RS04880	COG0366	Alpha amylase catalytic
AS200_RS04880	COG1470	cell adhesion involved in biofilm formation
AS200_RS04900	COG1366	Belongs to the anti-sigma-factor antagonist family
AS200_RS04920	COG0367	asparagine synthase
AS200_RS04925	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AS200_RS04925	COG2308	Evidence 4 Homologs of previously reported genes of
AS200_RS04970	COG1335	isochorismatase
AS200_RS04980	COG1136	(ABC) transporter
AS200_RS05075	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AS200_RS05110	COG1982	Orn Lys Arg decarboxylase major
AS200_RS05135	COG0574	Belongs to the PEP-utilizing enzyme family
AS200_RS05135	COG3848	Pyruvate phosphate dikinase
AS200_RS05140	COG0583	DNA-binding transcription factor activity
AS200_RS05165	COG0745	RESPONSE REGULATOR receiver
AS200_RS05170	COG2205	protein histidine kinase activity
AS200_RS05200	COG0577	efflux transmembrane transporter activity
AS200_RS05200	COG1136	(ABC) transporter
AS200_RS05205	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AS200_RS05210	COG0589	response to stress
AS200_RS05230	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AS200_RS05245	COG0745	RESPONSE REGULATOR receiver
AS200_RS05255	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AS200_RS05265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS200_RS05270	COG0500	methyltransferase
AS200_RS05285	COG1937	Protein conserved in bacteria
AS200_RS05290	COG0730	response to heat
AS200_RS05295	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AS200_RS05300	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AS200_RS05300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS200_RS05315	COG0477	Major facilitator Superfamily
AS200_RS05345	COG3469	chitinase activity
AS200_RS05360	COG3507	Belongs to the glycosyl hydrolase 43 family
AS200_RS05380	COG3469	chitinase activity
AS200_RS05400	COG4977	sequence-specific DNA binding
AS200_RS05405	COG0477	Major facilitator Superfamily
AS200_RS05410	COG1846	Transcriptional regulator
AS200_RS05420	COG0531	amino acid
AS200_RS05435	COG0477	Major facilitator Superfamily
AS200_RS05460	COG2188	Transcriptional regulator
AS200_RS05470	COG1176	ABC-type spermidine putrescine transport system, permease component I
AS200_RS05480	COG3842	ATPase activity
AS200_RS05525	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AS200_RS05530	COG0515	serine threonine protein kinase
AS200_RS05535	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AS200_RS05570	COG0456	acetyltransferase
AS200_RS05580	COG3290	protein histidine kinase activity
AS200_RS05640	COG2080	2 iron, 2 sulfur cluster binding
AS200_RS05645	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AS200_RS05650	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AS200_RS05700	COG1132	(ABC) transporter
AS200_RS05705	COG0667	Aldo Keto reductase
AS200_RS05710	COG0673	inositol 2-dehydrogenase activity
AS200_RS05785	COG0395	ABC-type sugar transport system, permease component
AS200_RS05790	COG1175	transmembrane transport
AS200_RS05800	COG1940	carbohydrate kinase activity
AS200_RS05855	COG2050	protein possibly involved in aromatic compounds catabolism
AS200_RS05890	COG1940	carbohydrate kinase activity
AS200_RS05890	COG1846	Transcriptional regulator
AS200_RS05930	COG1132	(ABC) transporter
AS200_RS05955	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AS200_RS06000	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AS200_RS06010	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AS200_RS06035	COG1335	isochorismatase
AS200_RS06080	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AS200_RS06095	COG1846	Transcriptional regulator
AS200_RS06105	COG0515	serine threonine protein kinase
AS200_RS06115	COG1132	(ABC) transporter
AS200_RS06120	COG1132	(ABC) transporter
AS200_RS06165	COG0248	Ppx GppA phosphatase
AS200_RS06175	COG2890	protein-(glutamine-N5) methyltransferase activity
AS200_RS06220	COG1595	DNA-templated transcription, initiation
AS200_RS06240	COG0667	Aldo Keto reductase
AS200_RS06265	COG2815	serine threonine protein kinase
AS200_RS06265	COG0515	serine threonine protein kinase
AS200_RS06280	COG1309	transcriptional regulator
AS200_RS06285	COG1028	Short-chain dehydrogenase reductase Sdr
AS200_RS06290	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AS200_RS06305	COG1595	DNA-templated transcription, initiation
AS200_RS06340	COG0667	Aldo Keto reductase
AS200_RS06365	COG2124	cytochrome p450
AS200_RS06380	COG0435	Glutathione S-transferase
AS200_RS06400	COG0531	amino acid
AS200_RS06405	COG1228	amidohydrolase
AS200_RS06470	COG1012	belongs to the aldehyde dehydrogenase family
AS200_RS06490	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AS200_RS06500	COG2124	cytochrome p450
AS200_RS06510	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AS200_RS06515	COG1006	Multisubunit Na H antiporter MnhC subunit
AS200_RS06560	COG1028	Short-chain dehydrogenase reductase Sdr
AS200_RS06565	COG1796	DNA polymerase
AS200_RS06565	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AS200_RS06605	COG0437	4 iron, 4 sulfur cluster binding
AS200_RS06610	COG3383	formate dehydrogenase (NAD+) activity
AS200_RS06610	COG0243	molybdopterin cofactor binding
AS200_RS06630	COG2124	cytochrome p450
AS200_RS06630	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AS200_RS06640	COG0366	Alpha amylase catalytic
AS200_RS06670	COG2706	6-phosphogluconolactonase activity
AS200_RS06680	COG1309	transcriptional regulator
AS200_RS06690	COG1357	PFAM Pentapeptide repeats (8 copies)
AS200_RS06710	COG1609	Transcriptional regulator
AS200_RS06725	COG1879	ABC-type sugar transport system periplasmic component
AS200_RS06730	COG1172	Belongs to the binding-protein-dependent transport system permease family
AS200_RS06735	COG1172	Belongs to the binding-protein-dependent transport system permease family
AS200_RS06740	COG1129	ABC transporter
AS200_RS06755	COG0583	DNA-binding transcription factor activity
AS200_RS06760	COG1090	epimerase
AS200_RS06765	COG3250	beta-galactosidase activity
AS200_RS06775	COG3347	Dehydrogenase
AS200_RS06775	COG1028	Short-chain dehydrogenase reductase Sdr
AS200_RS06780	COG1070	Carbohydrate kinase
AS200_RS06785	COG0247	lactate metabolic process
AS200_RS06790	COG1139	Iron-sulfur cluster binding protein
AS200_RS06795	COG1556	Lactate utilization protein
AS200_RS06815	COG0542	response to heat
AS200_RS06890	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AS200_RS06895	COG0477	Major facilitator Superfamily
AS200_RS06905	COG1605	Chorismate mutase
AS200_RS06905	COG0077	Prephenate dehydratase
AS200_RS06910	COG0488	(ABC) transporter
AS200_RS06930	COG2205	protein histidine kinase activity
AS200_RS06965	COG0242	peptide deformylase activity
AS200_RS06975	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS200_RS06990	COG1609	Transcriptional regulator
AS200_RS07015	COG0583	DNA-binding transcription factor activity
AS200_RS07045	COG2814	Major facilitator Superfamily
AS200_RS07060	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AS200_RS07070	COG2188	Transcriptional regulator
AS200_RS07075	COG0300	oxidoreductase activity
AS200_RS07170	COG1028	Short-chain dehydrogenase reductase Sdr
AS200_RS07185	COG1252	NADH dehydrogenase
AS200_RS07190	COG0137	argininosuccinate synthase activity
AS200_RS07205	COG4948	Mandelate Racemase Muconate Lactonizing
AS200_RS07210	COG2610	gluconate transmembrane transporter activity
AS200_RS07220	COG0673	inositol 2-dehydrogenase activity
AS200_RS07255	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AS200_RS07255	COG0475	glutathione-regulated potassium exporter activity
AS200_RS07310	COG0326	Molecular chaperone. Has ATPase activity
AS200_RS07320	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
AS200_RS07320	COG3408	Glycogen debranching enzyme
AS200_RS07360	COG1366	Belongs to the anti-sigma-factor antagonist family
AS200_RS07365	COG5002	protein histidine kinase activity
AS200_RS07365	COG0784	Response regulator, receiver
AS200_RS07365	COG2205	protein histidine kinase activity
AS200_RS07420	COG1215	transferase activity, transferring glycosyl groups
AS200_RS07485	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AS200_RS07490	COG1088	dTDP-glucose 4,6-dehydratase activity
AS200_RS07500	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AS200_RS07545	COG2268	Band 7 protein
AS200_RS07580	COG3572	ergothioneine biosynthetic process
AS200_RS07585	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AS200_RS07590	COG0121	glutamine amidotransferase
AS200_RS07595	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
AS200_RS07640	COG1028	Short-chain dehydrogenase reductase Sdr
AS200_RS07645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS200_RS07665	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AS200_RS07720	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AS200_RS07725	COG1053	succinate dehydrogenase
AS200_RS07735	COG0583	DNA-binding transcription factor activity
AS200_RS07740	COG1028	Short-chain dehydrogenase reductase Sdr
AS200_RS07750	COG2197	response regulator
AS200_RS07795	COG0726	polysaccharide deacetylase
AS200_RS07840	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AS200_RS07875	COG1028	Short-chain dehydrogenase reductase Sdr
AS200_RS07880	COG4948	Mandelate Racemase Muconate Lactonizing
AS200_RS07890	COG1129	ABC transporter
AS200_RS07895	COG1879	ABC-type sugar transport system periplasmic component
AS200_RS07900	COG2186	Transcriptional regulator
AS200_RS07910	COG4941	Belongs to the sigma-70 factor family
AS200_RS07915	COG3795	YCII-related domain
AS200_RS07940	COG0395	ABC-type sugar transport system, permease component
AS200_RS07945	COG1175	transmembrane transport
AS200_RS07950	COG1653	transport
AS200_RS07955	COG1609	Transcriptional regulator
AS200_RS07960	COG2030	dehydratase
AS200_RS07965	COG0586	Pfam SNARE associated Golgi protein
AS200_RS07980	COG3842	ATPase activity
AS200_RS07985	COG0701	Predicted permease
AS200_RS07995	COG1028	Short-chain dehydrogenase reductase Sdr
AS200_RS08015	COG3537	Alpha-1,2-mannosidase
AS200_RS08025	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AS200_RS08030	COG0297	glycogen (starch) synthase activity
AS200_RS08050	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AS200_RS08060	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AS200_RS08065	COG1028	Short-chain dehydrogenase reductase Sdr
AS200_RS08085	COG2197	response regulator
AS200_RS08135	COG0513	Belongs to the DEAD box helicase family
AS200_RS08140	COG3693	PFAM glycoside hydrolase, family 10
AS200_RS08150	COG0531	amino acid
AS200_RS08160	COG1113	amino acid transport
AS200_RS08165	COG1132	(ABC) transporter
AS200_RS08175	COG1028	Short-chain dehydrogenase reductase Sdr
AS200_RS08180	COG1024	Enoyl-CoA hydratase
AS200_RS08185	COG0668	transmembrane transport
AS200_RS08195	COG2838	Isocitrate dehydrogenase
AS200_RS08230	COG1595	DNA-templated transcription, initiation
AS200_RS08235	COG2197	response regulator
AS200_RS08260	COG0697	spore germination
AS200_RS08275	COG1132	(ABC) transporter
AS200_RS08280	COG1595	DNA-templated transcription, initiation
AS200_RS08300	COG4221	oxidoreductase activity
AS200_RS08310	COG0477	Major facilitator Superfamily
AS200_RS08320	COG1234	tRNA 3'-trailer cleavage
AS200_RS08330	COG2814	Major facilitator Superfamily
AS200_RS08345	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AS200_RS08350	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AS200_RS08360	COG1454	alcohol dehydrogenase
AS200_RS08380	COG1609	Transcriptional regulator
AS200_RS08395	COG1609	Transcriptional regulator
AS200_RS08405	COG1028	Short-chain dehydrogenase reductase Sdr
AS200_RS08410	COG0673	inositol 2-dehydrogenase activity
AS200_RS08430	COG0673	inositol 2-dehydrogenase activity
AS200_RS08450	COG1879	ABC-type sugar transport system periplasmic component
AS200_RS08455	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AS200_RS08465	COG3718	enzyme involved in inositol metabolism
AS200_RS08470	COG3962	Belongs to the TPP enzyme family
AS200_RS08480	COG2188	Transcriptional regulator
AS200_RS08490	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AS200_RS08495	COG0438	transferase activity, transferring glycosyl groups
AS200_RS08505	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AS200_RS08565	COG1316	TRANSCRIPTIONal
AS200_RS08570	COG1086	Polysaccharide biosynthesis protein
AS200_RS08575	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AS200_RS08625	COG0254	rRNA binding
AS200_RS08630	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AS200_RS08640	COG2267	carboxylic ester hydrolase activity
AS200_RS08665	COG1917	Cupin 2, conserved barrel domain protein
AS200_RS08670	COG0402	S-adenosylhomocysteine deaminase activity
AS200_RS08675	COG0022	dehydrogenase e1 component
AS200_RS08680	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AS200_RS08685	COG0006	proline dipeptidase activity
AS200_RS08690	COG1396	sequence-specific DNA binding
AS200_RS08715	COG0174	glutamine synthetase
AS200_RS08755	COG0494	nUDIX hydrolase
AS200_RS08760	COG0366	Alpha amylase catalytic
AS200_RS08795	COG2268	Band 7 protein
AS200_RS08820	COG1937	Protein conserved in bacteria
AS200_RS08845	COG0583	DNA-binding transcription factor activity
AS200_RS08850	COG0156	8-amino-7-oxononanoate synthase activity
AS200_RS08855	COG1063	alcohol dehydrogenase
AS200_RS08865	COG1028	Short-chain dehydrogenase reductase Sdr
AS200_RS08870	COG0583	DNA-binding transcription factor activity
AS200_RS08880	COG0477	Major facilitator Superfamily
AS200_RS08890	COG1309	transcriptional regulator
AS200_RS08925	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AS200_RS08935	COG2755	lipolytic protein G-D-S-L family
AS200_RS08950	COG2365	Tyrosine phosphatase family
AS200_RS08970	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AS200_RS08975	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AS200_RS08990	COG1657	PFAM Prenyltransferase squalene oxidase
AS200_RS09000	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AS200_RS09010	COG1562	ergosterol biosynthetic process
AS200_RS09015	COG1388	LysM domain
AS200_RS09015	COG1134	teichoic acid transport
AS200_RS09060	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AS200_RS09070	COG1024	Enoyl-CoA hydratase
AS200_RS09080	COG2183	response to ionizing radiation
AS200_RS09085	COG0488	(ABC) transporter
AS200_RS09100	COG2936	dipeptidyl-peptidase activity
AS200_RS09110	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AS200_RS09120	COG1113	amino acid transport
AS200_RS09140	COG1250	3-hydroxyacyl-CoA dehydrogenase
AS200_RS09140	COG1024	Enoyl-CoA hydratase
AS200_RS09145	COG0183	Belongs to the thiolase family
AS200_RS09150	COG1960	acyl-CoA dehydrogenase activity
AS200_RS09155	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AS200_RS09160	COG3268	Saccharopine dehydrogenase
AS200_RS09165	COG1515	deoxyribonuclease V activity
AS200_RS09195	COG0488	(ABC) transporter
AS200_RS09200	COG1834	amidinotransferase
AS200_RS09240	COG1793	dna ligase
AS200_RS09270	COG0183	Belongs to the thiolase family
AS200_RS09275	COG3485	protocatechuate 3,4-dioxygenase
AS200_RS09280	COG3485	protocatechuate 3,4-dioxygenase
AS200_RS09285	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AS200_RS09290	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AS200_RS09300	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AS200_RS09300	COG1672	PFAM Archaeal ATPase
AS200_RS09305	COG3547	Transposase (IS116 IS110 IS902 family)
AS200_RS09335	COG3511	phospholipase C
AS200_RS09365	COG0596	Alpha beta hydrolase
AS200_RS09420	COG0730	response to heat
AS200_RS09440	COG1968	undecaprenyl-diphosphatase activity
AS200_RS09445	COG0671	phosphoesterase, PA-phosphatase related
AS200_RS09460	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AS200_RS09500	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AS200_RS09515	COG2814	Major facilitator Superfamily
AS200_RS09525	COG0768	penicillin binding
AS200_RS09570	COG2205	protein histidine kinase activity
AS200_RS09585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS200_RS09590	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AS200_RS09610	COG0500	methyltransferase
AS200_RS09615	COG0450	alkyl hydroperoxide reductase
AS200_RS09625	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AS200_RS09635	COG2920	part of a sulfur-relay system
AS200_RS09640	COG1252	NADH dehydrogenase
AS200_RS09655	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS200_RS09660	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
AS200_RS09665	COG1937	Protein conserved in bacteria
AS200_RS09670	COG0730	response to heat
AS200_RS09675	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AS200_RS09680	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AS200_RS09680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS200_RS09690	COG2226	methyltransferase
AS200_RS09705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS200_RS09735	COG0640	Transcriptional regulator
AS200_RS09740	COG0701	Predicted permease
AS200_RS09750	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AS200_RS09770	COG2346	COG2346, Truncated hemoglobins
AS200_RS09780	COG0366	Alpha amylase catalytic
AS200_RS09785	COG0395	ABC-type sugar transport system, permease component
AS200_RS09790	COG1175	transmembrane transport
AS200_RS09810	COG3938	Belongs to the proline racemase family
AS200_RS09815	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AS200_RS09830	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AS200_RS09835	COG1177	transmembrane transport
AS200_RS09840	COG1176	ABC-type spermidine putrescine transport system, permease component I
AS200_RS09845	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AS200_RS09850	COG3842	ATPase activity
AS200_RS09890	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AS200_RS09900	COG3469	chitinase activity
AS200_RS09910	COG1486	melibiose metabolic process
AS200_RS09915	COG1349	DNA-binding transcription factor activity
AS200_RS09920	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AS200_RS09930	COG1175	transmembrane transport
AS200_RS09935	COG0395	ABC-type sugar transport system, permease component
AS200_RS09940	COG3250	beta-galactosidase activity
AS200_RS09945	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AS200_RS09975	COG1028	Short-chain dehydrogenase reductase Sdr
AS200_RS10000	COG2197	response regulator
AS200_RS10010	COG2409	Drug exporters of the RND superfamily
AS200_RS10035	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AS200_RS10050	COG0166	Belongs to the GPI family
AS200_RS10055	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AS200_RS10060	COG0588	phosphoglycerate mutase activity
AS200_RS10070	COG3185	4-Hydroxyphenylpyruvate dioxygenase
AS200_RS10070	COG1082	Xylose isomerase domain protein TIM barrel
AS200_RS10075	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AS200_RS10085	COG0477	Major facilitator Superfamily
AS200_RS10095	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AS200_RS10100	COG0346	lactoylglutathione lyase activity
AS200_RS10105	COG3467	pyridoxamine 5'-phosphate
AS200_RS10115	COG0477	Major facilitator Superfamily
AS200_RS10140	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AS200_RS10155	COG0438	transferase activity, transferring glycosyl groups
AS200_RS10190	COG4166	transmembrane transport
AS200_RS10210	COG2723	6-phospho-beta-galactosidase activity
AS200_RS10215	COG0395	ABC-type sugar transport system, permease component
AS200_RS10220	COG1175	transmembrane transport
AS200_RS10225	COG2182	Extracellular solute-binding protein
AS200_RS10235	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AS200_RS10255	COG3594	Acyltransferase
AS200_RS10275	COG1012	belongs to the aldehyde dehydrogenase family
AS200_RS10285	COG0045	succinate-CoA ligase (ADP-forming) activity
AS200_RS10295	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AS200_RS10305	COG2223	nitrite transmembrane transporter activity
AS200_RS10330	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AS200_RS10340	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AS200_RS10345	COG3383	formate dehydrogenase (NAD+) activity
AS200_RS10360	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AS200_RS10365	COG1335	isochorismatase
AS200_RS10405	COG0477	Major facilitator Superfamily
AS200_RS10415	COG3250	beta-galactosidase activity
AS200_RS10420	COG3469	chitinase activity
AS200_RS10435	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AS200_RS10440	COG0656	L-ascorbic acid biosynthetic process
AS200_RS10465	COG5297	Belongs to the glycosyl hydrolase family 6
AS200_RS10475	COG4733	cellulase activity
AS200_RS10475	COG5297	Belongs to the glycosyl hydrolase family 6
AS200_RS10485	COG2378	regulation of single-species biofilm formation
AS200_RS10500	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AS200_RS10505	COG2154	pterin-4-alpha-carbinolamine dehydratase
AS200_RS10530	COG0443	Heat shock 70 kDa protein
AS200_RS10590	COG0028	Belongs to the TPP enzyme family
AS200_RS10615	COG0693	protein deglycase activity
AS200_RS10630	COG0488	(ABC) transporter
AS200_RS10635	COG0406	alpha-ribazole phosphatase activity
AS200_RS10695	COG1793	dna ligase
AS200_RS10695	COG3285	dna ligase
AS200_RS10700	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AS200_RS10710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS200_RS10715	COG4948	Mandelate Racemase Muconate Lactonizing
AS200_RS10745	COG1619	proteins homologs of microcin C7 resistance protein MccF
AS200_RS10750	COG1506	peptidase
AS200_RS10750	COG4946	Tricorn protease homolog
AS200_RS10750	COG0823	Involved in the tonB-independent uptake of proteins
AS200_RS10755	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AS200_RS10760	COG2362	D-Aminopeptidase
AS200_RS10775	COG2172	sigma factor antagonist activity
AS200_RS10775	COG2208	phosphoserine phosphatase activity
AS200_RS10775	COG1366	Belongs to the anti-sigma-factor antagonist family
AS200_RS10795	COG0596	Alpha beta hydrolase
AS200_RS10810	COG1250	3-hydroxyacyl-CoA dehydrogenase
AS200_RS10825	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AS200_RS10825	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AS200_RS10840	COG1960	acyl-CoA dehydrogenase activity
AS200_RS10845	COG0688	phosphatidylethanolamine metabolic process
AS200_RS10855	COG1929	Belongs to the glycerate kinase type-1 family
AS200_RS10865	COG0494	nUDIX hydrolase
AS200_RS10875	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AS200_RS10890	COG0640	Transcriptional regulator
AS200_RS10895	COG2814	Major facilitator Superfamily
AS200_RS10915	COG0671	phosphoesterase, PA-phosphatase related
AS200_RS10920	COG0671	phosphoesterase, PA-phosphatase related
AS200_RS10925	COG0586	Pfam SNARE associated Golgi protein
AS200_RS10955	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AS200_RS10965	COG0483	inositol monophosphate 1-phosphatase activity
AS200_RS10985	COG2197	response regulator
AS200_RS10990	COG3851	Histidine kinase
AS200_RS11005	COG1953	Uracil, thiamine, allantoin
AS200_RS11015	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AS200_RS11055	COG0542	response to heat
AS200_RS11060	COG0405	Gamma-glutamyltransferase
AS200_RS11075	COG1126	abc transporter atp-binding protein
AS200_RS11090	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AS200_RS11095	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AS200_RS11110	COG1140	nitrate reductase beta subunit
AS200_RS11130	COG0535	radical SAM domain protein
AS200_RS11150	COG1140	nitrate reductase beta subunit
AS200_RS11155	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AS200_RS11180	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AS200_RS11190	COG1940	carbohydrate kinase activity
AS200_RS11195	COG2188	Transcriptional regulator
AS200_RS11200	COG0673	inositol 2-dehydrogenase activity
AS200_RS11210	COG2197	response regulator
AS200_RS11240	COG1028	Short-chain dehydrogenase reductase Sdr
AS200_RS11245	COG4266	Belongs to the allantoicase family
AS200_RS11250	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AS200_RS11255	COG1414	Transcriptional regulator
AS200_RS11270	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AS200_RS11290	COG4264	IucA IucC family
AS200_RS11335	COG3548	integral membrane protein
AS200_RS11340	COG2233	PERMEase
AS200_RS11355	COG2351	hydroxyisourate hydrolase activity
AS200_RS11375	COG1796	DNA polymerase
AS200_RS11375	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AS200_RS11380	COG3622	Belongs to the hyi family
AS200_RS11385	COG2084	Dehydrogenase
AS200_RS11390	COG0753	catalase activity
AS200_RS11400	COG3960	tartronate-semialdehyde synthase activity
AS200_RS11410	COG0318	PFAM AMP-dependent synthetase and ligase
AS200_RS11415	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AS200_RS11420	COG2197	response regulator
AS200_RS11440	COG0583	DNA-binding transcription factor activity
AS200_RS11450	COG0598	Magnesium transport protein CorA
AS200_RS11455	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AS200_RS11485	COG2252	PERMEase
AS200_RS11490	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AS200_RS11520	COG1802	Transcriptional regulator
AS200_RS11545	COG0028	Belongs to the TPP enzyme family
AS200_RS11565	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AS200_RS11575	COG1162	GTPase activity
AS200_RS11600	COG0277	FAD linked oxidase domain protein
AS200_RS11610	COG1131	(ABC) transporter
AS200_RS11655	COG2755	lipolytic protein G-D-S-L family
AS200_RS11665	COG3328	transposase activity
AS200_RS11680	COG0531	amino acid
AS200_RS11685	COG2040	homocysteine
AS200_RS11695	COG1609	Transcriptional regulator
AS200_RS11725	COG1917	Cupin 2, conserved barrel domain protein
AS200_RS11725	COG4977	sequence-specific DNA binding
AS200_RS11735	COG1960	acyl-CoA dehydrogenase activity
AS200_RS11760	COG0175	sulfate reduction
AS200_RS11765	COG0529	Catalyzes the synthesis of activated sulfate
AS200_RS11795	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AS200_RS11805	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AS200_RS11815	COG2409	Drug exporters of the RND superfamily
AS200_RS11835	COG1175	transmembrane transport
AS200_RS11845	COG0583	DNA-binding transcription factor activity
AS200_RS11920	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AS200_RS11925	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AS200_RS11940	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AS200_RS11945	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AS200_RS11970	COG1309	transcriptional regulator
AS200_RS11995	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AS200_RS12005	COG0640	Transcriptional regulator
AS200_RS12035	COG2755	lipolytic protein G-D-S-L family
AS200_RS12050	COG2018	Roadblock/LC7 domain
AS200_RS12065	COG1174	glycine betaine transport
AS200_RS12070	COG1174	glycine betaine transport
AS200_RS12080	COG1477	protein flavinylation
AS200_RS12090	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AS200_RS12095	COG0745	RESPONSE REGULATOR receiver
AS200_RS12100	COG2205	protein histidine kinase activity
AS200_RS12110	COG5002	protein histidine kinase activity
AS200_RS12115	COG0745	RESPONSE REGULATOR receiver
AS200_RS12150	COG4821	SIS domain
AS200_RS12155	COG1737	Transcriptional regulator
AS200_RS12165	COG1472	Belongs to the glycosyl hydrolase 3 family
AS200_RS12175	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AS200_RS12180	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AS200_RS12210	COG0659	secondary active sulfate transmembrane transporter activity
AS200_RS12215	COG0330	HflC and HflK could
AS200_RS12220	COG1881	PFAM PEBP family protein
AS200_RS12225	COG2326	polyphosphate kinase activity
AS200_RS12255	COG3220	belongs to the UPF0276 family
AS200_RS12275	COG3253	May function as heme-dependent peroxidase
AS200_RS12290	COG0446	pyridine nucleotide-disulphide oxidoreductase
AS200_RS12305	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AS200_RS12320	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AS200_RS12325	COG3833	ABC-type maltose transport systems, permease component
AS200_RS12330	COG1175	transmembrane transport
AS200_RS12340	COG3250	beta-galactosidase activity
AS200_RS12345	COG1609	Transcriptional regulator
AS200_RS12350	COG0183	Belongs to the thiolase family
AS200_RS12355	COG1250	3-hydroxyacyl-CoA dehydrogenase
AS200_RS12355	COG1024	Enoyl-CoA hydratase
AS200_RS12360	COG1316	TRANSCRIPTIONal
AS200_RS12380	COG0531	amino acid
AS200_RS12385	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AS200_RS12390	COG4214	carbohydrate transport
AS200_RS12400	COG4213	ABC transporter substrate-binding protein
AS200_RS12405	COG1940	carbohydrate kinase activity
AS200_RS12410	COG0395	ABC-type sugar transport system, permease component
AS200_RS12415	COG1175	transmembrane transport
AS200_RS12420	COG1653	transport
AS200_RS12430	COG3537	Alpha-1,2-mannosidase
AS200_RS12445	COG2205	protein histidine kinase activity
AS200_RS12450	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AS200_RS12455	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AS200_RS12505	COG0529	Catalyzes the synthesis of activated sulfate
AS200_RS12525	COG1024	Enoyl-CoA hydratase
AS200_RS12535	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AS200_RS12540	COG2235	arginine
AS200_RS12555	COG2814	Major facilitator Superfamily
AS200_RS12565	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AS200_RS12600	COG1799	cell septum assembly
AS200_RS12610	COG2353	YceI-like domain
AS200_RS12620	COG0277	FAD linked oxidase domain protein
AS200_RS12620	COG0247	lactate metabolic process
AS200_RS12640	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AS200_RS12640	COG3608	succinylglutamate desuccinylase aspartoacylase
AS200_RS12660	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AS200_RS12665	COG0531	amino acid
AS200_RS12670	COG0569	domain protein
AS200_RS12700	COG1136	(ABC) transporter
AS200_RS12700	COG4591	ABC-type transport system involved in lipoprotein release permease component
AS200_RS12715	COG0756	dUTP diphosphatase activity
AS200_RS12740	COG2205	protein histidine kinase activity
AS200_RS12755	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AS200_RS12785	COG1435	thymidine kinase activity
AS200_RS12800	COG0045	succinate-CoA ligase (ADP-forming) activity
AS200_RS12800	COG1042	CoA-binding domain protein
AS200_RS12800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS200_RS12805	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AS200_RS12810	COG1802	Transcriptional regulator
AS200_RS12825	COG0612	Peptidase, M16
AS200_RS12830	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AS200_RS12835	COG0523	cobalamin synthesis protein
AS200_RS12850	COG0372	Belongs to the citrate synthase family
AS200_RS12865	COG2814	Major facilitator Superfamily
AS200_RS12875	COG3290	protein histidine kinase activity
AS200_RS12890	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AS200_RS12900	COG4565	transcriptional regulatory protein
AS200_RS12915	COG2197	response regulator
AS200_RS12920	COG4585	Histidine kinase
AS200_RS12930	COG0187	DNA topoisomerase II activity
AS200_RS12945	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AS200_RS12950	COG1802	Transcriptional regulator
AS200_RS12955	COG1126	abc transporter atp-binding protein
AS200_RS12990	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AS200_RS13010	COG0588	phosphoglycerate mutase activity
AS200_RS13030	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AS200_RS13035	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AS200_RS13040	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AS200_RS13070	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AS200_RS13080	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AS200_RS13085	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AS200_RS13095	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AS200_RS13115	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AS200_RS13135	COG2358	TRAP transporter, solute receptor (TAXI family
AS200_RS13140	COG2205	protein histidine kinase activity
AS200_RS13145	COG0745	RESPONSE REGULATOR receiver
AS200_RS13150	COG1126	abc transporter atp-binding protein
AS200_RS13155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AS200_RS13160	COG0765	amino acid transport
AS200_RS13165	COG0765	amino acid transport
AS200_RS13180	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AS200_RS13190	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AS200_RS13195	COG0628	permease
AS200_RS13220	COG1917	Cupin 2, conserved barrel domain protein
AS200_RS13220	COG2207	Transcriptional regulator
AS200_RS13225	COG1201	RNA secondary structure unwinding
AS200_RS13230	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AS200_RS13235	COG1028	Short-chain dehydrogenase reductase Sdr
AS200_RS13240	COG0783	Belongs to the Dps family
AS200_RS13245	COG1396	sequence-specific DNA binding
AS200_RS13250	COG1546	Belongs to the CinA family
AS200_RS13250	COG1058	Belongs to the CinA family
AS200_RS13260	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AS200_RS13270	COG1674	ftsk spoiiie
AS200_RS13280	COG0784	Response regulator, receiver
AS200_RS13280	COG2205	protein histidine kinase activity
AS200_RS13285	COG2208	phosphoserine phosphatase activity
AS200_RS13285	COG2770	Histidine kinase
AS200_RS13315	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AS200_RS13320	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AS200_RS13345	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AS200_RS13350	COG0612	Peptidase, M16
AS200_RS13355	COG1185	polyribonucleotide nucleotidyltransferase activity
AS200_RS13360	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AS200_RS13375	COG1674	ftsk spoiiie
AS200_RS13565	COG1404	Belongs to the peptidase S8 family
AS200_RS13595	COG0455	bacterial-type flagellum organization
AS200_RS13610	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AS200_RS13615	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AS200_RS13625	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AS200_RS13640	COG0779	Required for maturation of 30S ribosomal subunits
AS200_RS13685	COG0442	prolyl-tRNA aminoacylation
AS200_RS13700	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AS200_RS13705	COG0750	zinc metalloprotease
AS200_RS13710	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AS200_RS13730	COG1605	Chorismate mutase
AS200_RS13750	COG0395	ABC-type sugar transport system, permease component
AS200_RS13755	COG4209	transmembrane transport
AS200_RS13770	COG1012	belongs to the aldehyde dehydrogenase family
AS200_RS13775	COG2508	Transcriptional regulator
AS200_RS13805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AS200_RS13810	COG1177	transmembrane transport
AS200_RS13815	COG1176	ABC-type spermidine putrescine transport system, permease component I
AS200_RS13820	COG3842	ATPase activity
AS200_RS13845	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AS200_RS13850	COG0584	glycerophosphoryl diester phosphodiesterase
AS200_RS13870	COG1595	DNA-templated transcription, initiation
AS200_RS13885	COG2353	YceI-like domain
AS200_RS13895	COG1012	belongs to the aldehyde dehydrogenase family
AS200_RS13905	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AS200_RS13910	COG1136	(ABC) transporter
AS200_RS13955	COG3842	ATPase activity
AS200_RS13960	COG4149	molybdate abc transporter
AS200_RS13970	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AS200_RS13990	COG0575	Belongs to the CDS family
AS200_RS13995	COG0233	cytoplasmic translational termination
AS200_RS14000	COG0528	UMP kinase activity
AS200_RS14005	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AS200_RS14010	COG0052	Belongs to the universal ribosomal protein uS2 family
AS200_RS14015	COG4942	peptidase
AS200_RS14025	COG1191	sigma factor activity
AS200_RS14205	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
AS200_RS14210	COG2304	oxidoreductase activity
AS200_RS14225	COG0596	Alpha beta hydrolase
AS200_RS14265	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AS200_RS14270	COG0789	Transcriptional regulator
AS200_RS14280	COG3547	Transposase (IS116 IS110 IS902 family)
AS200_RS14285	COG3547	Transposase (IS116 IS110 IS902 family)
AS200_RS14300	COG2132	Multicopper oxidase
AS200_RS14310	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AS200_RS14335	COG1013	pyruvate-flavodoxin oxidoreductase activity
AS200_RS14340	COG0674	pyruvate-flavodoxin oxidoreductase activity
AS200_RS14340	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AS200_RS14345	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
AS200_RS14360	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AS200_RS14390	COG0745	RESPONSE REGULATOR receiver
AS200_RS14395	COG0642	Histidine kinase
AS200_RS14485	COG2815	serine threonine protein kinase
AS200_RS14485	COG0515	serine threonine protein kinase
AS200_RS14510	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
AS200_RS14515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AS200_RS14520	COG0765	amino acid transport
AS200_RS14525	COG1126	abc transporter atp-binding protein
AS200_RS14540	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AS200_RS14555	COG0517	IMP dehydrogenase activity
AS200_RS14555	COG1994	Peptidase M50
AS200_RS14575	COG1376	ErfK ybiS ycfS ynhG family protein
AS200_RS14590	COG2132	Multicopper oxidase
AS200_RS14625	COG2267	carboxylic ester hydrolase activity
AS200_RS14640	COG1937	Protein conserved in bacteria
AS200_RS14650	COG2226	methyltransferase
AS200_RS14660	COG0785	Cytochrome C biogenesis protein
AS200_RS14680	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AS200_RS14685	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AS200_RS14715	COG4716	Myosin-crossreactive antigen
AS200_RS14720	COG1937	Protein conserved in bacteria
AS200_RS14760	COG1131	(ABC) transporter
AS200_RS14780	COG2132	Multicopper oxidase
AS200_RS14785	COG5002	protein histidine kinase activity
AS200_RS14790	COG0745	RESPONSE REGULATOR receiver
AS200_RS14795	COG0501	Belongs to the peptidase M48B family
AS200_RS14825	COG0438	transferase activity, transferring glycosyl groups
AS200_RS14835	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AS200_RS14865	COG2217	Heavy metal translocating P-type atpase
AS200_RS14930	COG0789	Transcriptional regulator
AS200_RS14950	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AS200_RS14970	COG1968	undecaprenyl-diphosphatase activity
AS200_RS14975	COG0492	ferredoxin-NADP+ reductase activity
AS200_RS15000	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AS200_RS15000	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AS200_RS15040	COG0745	RESPONSE REGULATOR receiver
AS200_RS15045	COG2205	protein histidine kinase activity
AS200_RS15060	COG2372	response to copper ion
AS200_RS15100	COG2226	methyltransferase
AS200_RS15140	COG0672	)-iron permease
AS200_RS15155	COG3328	transposase activity
AS200_RS15170	COG2132	Multicopper oxidase
AS200_RS15180	COG1937	Protein conserved in bacteria
AS200_RS15185	COG2217	Heavy metal translocating P-type atpase
AS200_RS15210	COG1121	(ABC) transporter
AS200_RS15220	COG3794	PFAM blue (type 1) copper domain protein
AS200_RS15240	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AS200_RS15360	COG0681	Belongs to the peptidase S26 family
AS200_RS15365	COG0681	Belongs to the peptidase S26 family
AS200_RS15375	COG0335	large ribosomal subunit rRNA binding
AS200_RS15385	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AS200_RS15390	COG1837	Belongs to the UPF0109 family
AS200_RS15395	COG0228	four-way junction DNA binding
AS200_RS15415	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AS200_RS15450	COG0477	Major facilitator Superfamily
AS200_RS15455	COG1196	nuclear chromosome segregation
AS200_RS15465	COG1254	Belongs to the acylphosphatase family
AS200_RS15470	COG2340	Cysteine-rich secretory protein family
AS200_RS15490	COG1733	regulation of RNA biosynthetic process
AS200_RS15495	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AS200_RS15500	COG0571	ribonuclease III activity
AS200_RS15505	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AS200_RS15520	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AS200_RS15525	COG0742	ribosomal rna small subunit methyltransferase
AS200_RS15535	COG0326	Molecular chaperone. Has ATPase activity
AS200_RS15545	COG1461	Dihydroxyacetone kinase
AS200_RS15550	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AS200_RS15560	COG0351	phosphomethylpyrimidine kinase
AS200_RS15580	COG1181	Belongs to the D-alanine--D-alanine ligase family
AS200_RS15585	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AS200_RS15595	COG1920	GTP binding
AS200_RS15605	COG0776	regulation of translation
AS200_RS15615	COG0066	3-isopropylmalate dehydratase activity
AS200_RS15620	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AS200_RS15625	COG1414	Transcriptional regulator
AS200_RS15670	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AS200_RS15675	COG0179	Fumarylacetoacetate (FAA) hydrolase
AS200_RS15685	COG5002	protein histidine kinase activity
AS200_RS15690	COG2018	Roadblock/LC7 domain
AS200_RS15710	COG2018	Roadblock/LC7 domain
AS200_RS15730	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AS200_RS15735	COG5492	domain, Protein
AS200_RS15740	COG2353	YceI-like domain
AS200_RS15765	COG1472	Belongs to the glycosyl hydrolase 3 family
AS200_RS15780	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AS200_RS15790	COG2957	Belongs to the agmatine deiminase family
AS200_RS15795	COG0804	urea catabolic process
AS200_RS15800	COG0832	Belongs to the urease beta subunit family
AS200_RS15800	COG0831	urea catabolic process
AS200_RS15810	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AS200_RS15815	COG0473	3-isopropylmalate dehydrogenase activity
AS200_RS15835	COG1012	belongs to the aldehyde dehydrogenase family
AS200_RS15840	COG0506	proline dehydrogenase activity
AS200_RS15845	COG2508	Transcriptional regulator
AS200_RS15850	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS200_RS15865	COG0477	Major facilitator Superfamily
AS200_RS15870	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AS200_RS15875	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AS200_RS15880	COG0440	acetolactate synthase activity
AS200_RS15890	COG5001	Diguanylate cyclase
AS200_RS15900	COG0667	Aldo Keto reductase
AS200_RS15905	COG2133	pyrroloquinoline quinone binding
AS200_RS15915	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AS200_RS15915	COG1672	PFAM Archaeal ATPase
AS200_RS15925	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS200_RS15930	COG2409	Drug exporters of the RND superfamily
AS200_RS15945	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AS200_RS15955	COG0154	amidase activity
AS200_RS15960	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AS200_RS15985	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AS200_RS15995	COG4221	oxidoreductase activity
AS200_RS16000	COG1611	Belongs to the LOG family
AS200_RS16015	COG0482	sulfurtransferase activity
AS200_RS16045	COG2378	regulation of single-species biofilm formation
AS200_RS16065	COG2860	membrane
AS200_RS16075	COG4608	Belongs to the ABC transporter superfamily
AS200_RS16080	COG0444	Belongs to the ABC transporter superfamily
AS200_RS16090	COG0747	negative chemotaxis
AS200_RS16115	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AS200_RS16120	COG0509	glycine decarboxylation via glycine cleavage system
AS200_RS16125	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AS200_RS16130	COG1760	l-serine dehydratase
AS200_RS16150	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AS200_RS16160	COG0789	Transcriptional regulator
AS200_RS16195	COG1376	ErfK ybiS ycfS ynhG family protein
AS200_RS16205	COG2197	response regulator
AS200_RS16220	COG1131	(ABC) transporter
AS200_RS16225	COG1132	(ABC) transporter
AS200_RS16230	COG1132	(ABC) transporter
AS200_RS16235	COG1132	(ABC) transporter
AS200_RS16240	COG1132	(ABC) transporter
AS200_RS16260	COG0058	SHG alpha-glucan phosphorylase activity
AS200_RS16270	COG0366	Alpha amylase catalytic
AS200_RS16280	COG3281	Trehalose synthase
AS200_RS16285	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AS200_RS16300	COG0789	Transcriptional regulator
AS200_RS16305	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AS200_RS16315	COG0477	Major facilitator Superfamily
AS200_RS16325	COG1301	dicarboxylic acid transport
AS200_RS16330	COG3290	protein histidine kinase activity
AS200_RS16335	COG4565	transcriptional regulatory protein
AS200_RS16345	COG1175	transmembrane transport
AS200_RS16350	COG0395	ABC-type sugar transport system, permease component
AS200_RS16360	COG0205	6-phosphofructokinase activity
AS200_RS16365	COG0857	belongs to the CobB CobQ family
AS200_RS16365	COG0280	phosphate acetyltransferase
AS200_RS16370	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AS200_RS16405	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AS200_RS16405	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AS200_RS16480	COG0183	Belongs to the thiolase family
AS200_RS16485	COG0346	lactoylglutathione lyase activity
AS200_RS16500	COG1131	(ABC) transporter
AS200_RS16535	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
AS200_RS16550	COG1250	3-hydroxyacyl-CoA dehydrogenase
AS200_RS16585	COG2205	protein histidine kinase activity
AS200_RS16590	COG0745	RESPONSE REGULATOR receiver
AS200_RS16600	COG4585	Histidine kinase
AS200_RS16605	COG2197	response regulator
AS200_RS16620	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AS200_RS16625	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AS200_RS16630	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AS200_RS16635	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AS200_RS16640	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AS200_RS16645	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AS200_RS16650	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AS200_RS16665	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AS200_RS16670	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AS200_RS16675	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AS200_RS16685	COG2890	protein-(glutamine-N5) methyltransferase activity
AS200_RS16690	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AS200_RS16695	COG0254	rRNA binding
AS200_RS16715	COG0083	homoserine kinase activity
AS200_RS16720	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AS200_RS16725	COG0460	homoserine dehydrogenase
AS200_RS16730	COG0019	diaminopimelate decarboxylase activity
AS200_RS16735	COG0018	arginyl-trna synthetase
AS200_RS16740	COG0745	RESPONSE REGULATOR receiver
AS200_RS16765	COG0515	serine threonine protein kinase
AS200_RS16765	COG2815	serine threonine protein kinase
AS200_RS16830	COG3336	cytochrome c oxidase
AS200_RS16835	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AS200_RS16835	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AS200_RS16860	COG2372	response to copper ion
AS200_RS16875	COG0288	reversible hydration of carbon dioxide
AS200_RS16900	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AS200_RS16935	COG2132	Multicopper oxidase
AS200_RS16945	COG1376	ErfK ybiS ycfS ynhG family protein
AS200_RS16970	COG2226	methyltransferase
AS200_RS17045	COG2217	Heavy metal translocating P-type atpase
AS200_RS17050	COG1937	Protein conserved in bacteria
AS200_RS17060	COG2132	Multicopper oxidase
AS200_RS17145	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AS200_RS17150	COG3285	dna ligase
AS200_RS17150	COG1793	dna ligase
AS200_RS17170	COG2205	protein histidine kinase activity
AS200_RS17185	COG0768	penicillin binding
AS200_RS17210	COG1309	transcriptional regulator
AS200_RS17220	COG0791	NLP P60 protein
AS200_RS17245	COG5002	protein histidine kinase activity
AS200_RS17270	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AS200_RS17275	COG3386	PFAM SMP-30 Gluconolaconase
AS200_RS17305	COG0745	RESPONSE REGULATOR receiver
AS200_RS17310	COG2205	protein histidine kinase activity
AS200_RS17315	COG0567	Dehydrogenase, E1 component
AS200_RS17315	COG0508	dehydrogenase complex catalyzes the overall conversion of
AS200_RS17390	COG0604	alcohol dehydrogenase
AS200_RS17395	COG0281	malic enzyme
AS200_RS17405	COG0765	amino acid transport
AS200_RS17415	COG4106	trans-aconitate 2-methyltransferase activity
AS200_RS17435	COG2326	polyphosphate kinase activity
AS200_RS17480	COG0142	geranyltranstransferase activity
AS200_RS17485	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AS200_RS17500	COG0025	NhaP-type Na H and K H
AS200_RS17525	COG1597	lipid kinase activity
AS200_RS17540	COG1309	transcriptional regulator
AS200_RS17545	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AS200_RS17550	COG0363	glucosamine-6-phosphate deaminase activity
AS200_RS17555	COG1472	Belongs to the glycosyl hydrolase 3 family
AS200_RS17560	COG0395	ABC-type sugar transport system, permease component
AS200_RS17565	COG1175	transmembrane transport
AS200_RS17570	COG2182	Extracellular solute-binding protein
AS200_RS17575	COG2188	Transcriptional regulator
AS200_RS17600	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AS200_RS17630	COG2124	cytochrome p450
AS200_RS17640	COG0242	peptide deformylase activity
AS200_RS17655	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AS200_RS17655	COG2199	diguanylate cyclase activity
AS200_RS17660	COG5662	AntiSigma factor
AS200_RS17665	COG1595	DNA-templated transcription, initiation
AS200_RS17675	COG2135	peptidase activity
AS200_RS17690	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AS200_RS17695	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AS200_RS17740	COG1595	DNA-templated transcription, initiation
AS200_RS17760	COG1595	DNA-templated transcription, initiation
AS200_RS17770	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AS200_RS17790	COG0483	inositol monophosphate 1-phosphatase activity
AS200_RS17820	COG1615	UPF0182 protein
AS200_RS17830	COG3480	Lon protease (S16) C-terminal proteolytic domain
AS200_RS17885	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AS200_RS17920	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AS200_RS17925	COG0210	DNA helicase
AS200_RS17985	COG0601	transmembrane transport
AS200_RS17990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AS200_RS17995	COG4166	transmembrane transport
AS200_RS18035	COG0513	Belongs to the DEAD box helicase family
AS200_RS18045	COG1432	Conserved Protein
AS200_RS18050	COG2095	MarC family integral membrane protein
AS200_RS18065	COG2814	Major facilitator Superfamily
AS200_RS18075	COG0598	Magnesium transport protein CorA
AS200_RS18110	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AS200_RS18125	COG1595	DNA-templated transcription, initiation
AS200_RS18135	COG1024	Enoyl-CoA hydratase
AS200_RS18140	COG0519	Catalyzes the synthesis of GMP from XMP
AS200_RS18150	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AS200_RS18155	COG1611	Belongs to the LOG family
AS200_RS18160	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AS200_RS18195	COG2197	response regulator
AS200_RS18200	COG4585	Histidine kinase
AS200_RS18210	COG1131	(ABC) transporter
AS200_RS18225	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AS200_RS18240	COG4608	Belongs to the ABC transporter superfamily
AS200_RS18250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AS200_RS18255	COG0601	transmembrane transport
AS200_RS18280	COG0601	transmembrane transport
AS200_RS18290	COG0444	Belongs to the ABC transporter superfamily
AS200_RS18300	COG0346	lactoylglutathione lyase activity
AS200_RS18305	COG4608	Belongs to the ABC transporter superfamily
AS200_RS18315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AS200_RS18330	COG1217	gtp-binding protein TYPA
AS200_RS18355	COG1053	succinate dehydrogenase
AS200_RS18360	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AS200_RS18440	COG2329	Antibiotic biosynthesis monooxygenase
AS200_RS18445	COG0662	Cupin 2, conserved barrel domain protein
AS200_RS18455	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AS200_RS18460	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AS200_RS18520	COG0012	GTP binding
AS200_RS18535	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AS200_RS18545	COG1570	exodeoxyribonuclease VII activity
AS200_RS18550	COG1722	exodeoxyribonuclease VII activity
AS200_RS18555	COG0778	Nitroreductase
AS200_RS18580	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AS200_RS18580	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AS200_RS18585	COG0114	fumarate hydratase activity
AS200_RS18600	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AS200_RS18610	COG1136	(ABC) transporter
AS200_RS18640	COG0741	lytic transglycosylase activity
AS200_RS18645	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AS200_RS18650	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AS200_RS18670	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AS200_RS18740	COG2894	cell division
AS200_RS18765	COG2610	gluconate transmembrane transporter activity
AS200_RS18770	COG0251	oxidation-reduction process
AS200_RS18775	COG1414	Transcriptional regulator
AS200_RS18790	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AS200_RS18805	COG0436	Aminotransferase
AS200_RS18835	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
AS200_RS18845	COG0477	Major facilitator Superfamily
AS200_RS18850	COG1309	transcriptional regulator
AS200_RS18860	COG1331	Highly conserved protein containing a thioredoxin domain
AS200_RS18885	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AS200_RS18895	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AS200_RS18910	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AS200_RS18915	COG2255	four-way junction helicase activity
AS200_RS18920	COG1595	DNA-templated transcription, initiation
AS200_RS18940	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AS200_RS19005	COG4585	Histidine kinase
AS200_RS19010	COG2197	response regulator
AS200_RS19030	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AS200_RS19035	COG1064	alcohol dehydrogenase
AS200_RS19050	COG1404	Belongs to the peptidase S8 family
AS200_RS19055	COG1136	(ABC) transporter
AS200_RS19085	COG2986	histidine ammonia-lyase
AS200_RS19095	COG1024	Enoyl-CoA hydratase
AS200_RS19105	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AS200_RS19115	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AS200_RS19125	COG0424	maF-like protein
AS200_RS19135	COG4770	biotin carboxylase activity
AS200_RS19165	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AS200_RS19175	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AS200_RS19180	COG1012	belongs to the aldehyde dehydrogenase family
AS200_RS19185	COG1012	belongs to the aldehyde dehydrogenase family
AS200_RS19200	COG1595	DNA-templated transcription, initiation
AS200_RS19205	COG0745	RESPONSE REGULATOR receiver
AS200_RS19210	COG2205	protein histidine kinase activity
AS200_RS19235	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AS200_RS19245	COG0583	DNA-binding transcription factor activity
AS200_RS19250	COG2814	Major facilitator Superfamily
AS200_RS19275	COG1079	Belongs to the binding-protein-dependent transport system permease family
AS200_RS19280	COG4603	Belongs to the binding-protein-dependent transport system permease family
AS200_RS19285	COG3845	ABC transporter
AS200_RS19290	COG1744	ABC transporter substrate-binding protein PnrA-like
AS200_RS19295	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AS200_RS19295	COG1473	amidohydrolase
AS200_RS19300	COG2226	methyltransferase
AS200_RS19310	COG2089	acid synthase
AS200_RS19325	COG1216	Glycosyl transferase, family 2
AS200_RS19350	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AS200_RS19350	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AS200_RS19365	COG1595	DNA-templated transcription, initiation
AS200_RS19415	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AS200_RS19425	COG2009	succinate dehydrogenase
AS200_RS19435	COG1053	succinate dehydrogenase
AS200_RS19480	COG2409	Drug exporters of the RND superfamily
AS200_RS19485	COG0745	RESPONSE REGULATOR receiver
AS200_RS19490	COG2205	protein histidine kinase activity
AS200_RS19505	COG1408	metallophosphoesterase
AS200_RS19515	COG1686	Belongs to the peptidase S11 family
AS200_RS19520	COG1295	ribonuclease BN
AS200_RS19550	COG0180	Tryptophanyl-tRNA synthetase
AS200_RS19560	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AS200_RS19565	COG0754	glutathionylspermidine amidase activity
AS200_RS19580	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AS200_RS19580	COG0512	Glutamine amidotransferase of anthranilate synthase
AS200_RS19585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS200_RS19590	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AS200_RS19595	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AS200_RS19615	COG0517	IMP dehydrogenase activity
AS200_RS19615	COG4175	Glycine betaine
AS200_RS19625	COG1012	belongs to the aldehyde dehydrogenase family
AS200_RS19655	COG0477	Major facilitator Superfamily
AS200_RS19665	COG0039	L-malate dehydrogenase activity
AS200_RS19685	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AS200_RS19695	COG0138	bifunctional purine biosynthesis protein purh
AS200_RS19725	COG0045	succinate-CoA ligase (ADP-forming) activity
AS200_RS19740	COG3552	Protein containing von Willebrand factor type A (VWA) domain
AS200_RS19745	COG2425	protein containing a von Willebrand factor type A (vWA) domain
AS200_RS19750	COG0714	Associated with various cellular activities
AS200_RS19765	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AS200_RS19765	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AS200_RS19775	COG0739	heme binding
AS200_RS19800	COG2197	response regulator
AS200_RS19850	COG0519	Catalyzes the synthesis of GMP from XMP
AS200_RS19850	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AS200_RS19875	COG1012	belongs to the aldehyde dehydrogenase family
AS200_RS19880	COG0515	serine threonine protein kinase
AS200_RS19885	COG0515	serine threonine protein kinase
AS200_RS19890	COG2815	serine threonine protein kinase
AS200_RS19890	COG0515	serine threonine protein kinase
AS200_RS19895	COG0515	serine threonine protein kinase
AS200_RS19905	COG2815	serine threonine protein kinase
AS200_RS19905	COG0515	serine threonine protein kinase
AS200_RS19910	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AS200_RS19920	COG0516	GMP reductase activity
AS200_RS19930	COG1595	DNA-templated transcription, initiation
AS200_RS19945	COG0583	DNA-binding transcription factor activity
AS200_RS19950	COG4221	oxidoreductase activity
AS200_RS19960	COG0459	protein refolding
AS200_RS19965	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AS200_RS19975	COG0726	polysaccharide deacetylase
AS200_RS19980	COG0726	polysaccharide deacetylase
AS200_RS19995	COG4941	Belongs to the sigma-70 factor family
AS200_RS20030	COG1609	Transcriptional regulator
AS200_RS20050	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AS200_RS20070	COG0802	atpase or kinase
AS200_RS20080	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AS200_RS20090	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AS200_RS20090	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AS200_RS20095	COG0736	holo-[acyl-carrier-protein] synthase activity
AS200_RS20110	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AS200_RS20115	COG1072	(Pantothenic acid kinase))
AS200_RS20125	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AS200_RS20130	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AS200_RS20135	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AS200_RS20145	COG0101	tRNA pseudouridine synthase activity
AS200_RS20150	COG0203	ribosomal protein L17
AS200_RS20155	COG0202	RNA polymerase activity
AS200_RS20160	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AS200_RS20165	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AS200_RS20170	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AS200_RS20175	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AS200_RS20185	COG0563	adenylate kinase activity
AS200_RS20195	COG0200	Binds to the 23S rRNA
AS200_RS20200	COG1841	ribosomal large subunit assembly
AS200_RS20205	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AS200_RS20210	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AS200_RS20215	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AS200_RS20220	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AS200_RS20225	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AS200_RS20230	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AS200_RS20235	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AS200_RS20240	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AS200_RS20245	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AS200_RS20250	COG0255	Belongs to the universal ribosomal protein uL29 family
AS200_RS20255	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AS200_RS20260	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AS200_RS20265	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AS200_RS20270	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AS200_RS20275	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AS200_RS20280	COG0089	rRNA binding
AS200_RS20285	COG0088	Forms part of the polypeptide exit tunnel
AS200_RS20290	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AS200_RS20295	COG0051	transcription antitermination factor activity, RNA binding
AS200_RS20315	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AS200_RS20320	COG0049	tRNA binding
AS200_RS20325	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AS200_RS20340	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AS200_RS20345	COG0085	RNA polymerase activity
AS200_RS20350	COG0222	ribosome binding
AS200_RS20355	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AS200_RS20370	COG0081	regulation of translation
AS200_RS20375	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AS200_RS20380	COG0250	Participates in transcription elongation, termination and antitermination
AS200_RS20395	COG0436	Aminotransferase
AS200_RS20400	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AS200_RS20405	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AS200_RS20425	COG2030	dehydratase
AS200_RS20430	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AS200_RS20445	COG0402	S-adenosylhomocysteine deaminase activity
AS200_RS20450	COG0702	epimerase
AS200_RS20510	COG0789	Transcriptional regulator
AS200_RS20675	COG1666	GTP binding
AS200_RS20680	COG2261	transglycosylase associated protein
AS200_RS20695	COG3304	Inner membrane component domain
AS200_RS20700	COG0501	Belongs to the peptidase M48B family
AS200_RS20705	COG1007	ATP synthesis coupled electron transport
AS200_RS20720	COG0713	ATP synthesis coupled electron transport
AS200_RS20725	COG0839	Belongs to the complex I subunit 6 family
AS200_RS20730	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AS200_RS20735	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AS200_RS20740	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AS200_RS20745	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AS200_RS20750	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AS200_RS20770	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AS200_RS20770	COG0674	pyruvate-flavodoxin oxidoreductase activity
AS200_RS20775	COG1013	pyruvate-flavodoxin oxidoreductase activity
AS200_RS20790	COG1733	regulation of RNA biosynthetic process
AS200_RS20795	COG0702	epimerase
AS200_RS20830	COG1131	(ABC) transporter
AS200_RS20845	COG0142	geranyltranstransferase activity
AS200_RS20855	COG0561	phosphatase activity
AS200_RS20860	COG0492	ferredoxin-NADP+ reductase activity
AS200_RS20880	COG0514	ATP-dependent DNA helicase (RecQ)
AS200_RS20885	COG1007	ATP synthesis coupled electron transport
AS200_RS20895	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AS200_RS20900	COG0713	ATP synthesis coupled electron transport
AS200_RS20910	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AS200_RS20915	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AS200_RS20920	COG1034	ATP synthesis coupled electron transport
AS200_RS20925	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AS200_RS20935	COG0649	NAD binding
AS200_RS20940	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AS200_RS20945	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AS200_RS20975	COG2226	methyltransferase
AS200_RS20985	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AS200_RS21005	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
AS200_RS21010	COG1278	Cold shock
AS200_RS21015	COG1396	sequence-specific DNA binding
AS200_RS21075	COG1309	transcriptional regulator
AS200_RS21090	COG1573	uracil-dna glycosylase
AS200_RS21095	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AS200_RS21105	COG0163	prenyltransferase activity
AS200_RS21115	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AS200_RS21120	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AS200_RS21150	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AS200_RS21155	COG1333	cytochrome c biogenesis protein
AS200_RS21160	COG0785	Cytochrome C biogenesis protein
AS200_RS21165	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS200_RS21180	COG0406	alpha-ribazole phosphatase activity
AS200_RS21185	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AS200_RS21215	COG2205	protein histidine kinase activity
AS200_RS21220	COG0745	RESPONSE REGULATOR receiver
AS200_RS21240	COG0604	alcohol dehydrogenase
AS200_RS21245	COG1733	regulation of RNA biosynthetic process
AS200_RS21250	COG1846	Transcriptional regulator
AS200_RS21260	COG1742	UPF0060 membrane protein
AS200_RS21280	COG1690	Belongs to the RtcB family
AS200_RS21300	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
AS200_RS21305	COG0018	arginyl-trna synthetase
AS200_RS21335	COG3773	Cell wall hydrolase
AS200_RS21335	COG3409	Peptidoglycan-binding domain 1 protein
AS200_RS21360	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS200_RS21375	COG3152	Membrane
AS200_RS21380	COG0113	porphobilinogen synthase activity
AS200_RS21385	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AS200_RS21385	COG1648	precorrin-2 dehydrogenase activity
AS200_RS21390	COG0181	hydroxymethylbilane synthase activity
AS200_RS21395	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AS200_RS21400	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AS200_RS21445	COG0123	including yeast histone deacetylase and acetoin utilization protein
AS200_RS21460	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AS200_RS21480	COG0180	Tryptophanyl-tRNA synthetase
AS200_RS21490	COG1335	isochorismatase
AS200_RS21495	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AS200_RS21505	COG1129	ABC transporter
AS200_RS21505	COG0842	Transport permease protein
AS200_RS21510	COG2226	methyltransferase
AS200_RS21520	COG4991	sh3 domain protein
AS200_RS21525	COG4991	sh3 domain protein
AS200_RS21535	COG0129	dihydroxy-acid dehydratase activity
AS200_RS21545	COG1082	Xylose isomerase domain protein TIM barrel
AS200_RS21550	COG0248	Ppx GppA phosphatase
AS200_RS21570	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
AS200_RS21585	COG1595	DNA-templated transcription, initiation
AS200_RS21595	COG0745	RESPONSE REGULATOR receiver
AS200_RS21600	COG2205	protein histidine kinase activity
AS200_RS21605	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AS200_RS21620	COG0477	Major facilitator Superfamily
AS200_RS21630	COG0739	heme binding
AS200_RS21655	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AS200_RS21675	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AS200_RS21685	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AS200_RS21690	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AS200_RS21715	COG1660	Displays ATPase and GTPase activities
AS200_RS21720	COG2197	response regulator
AS200_RS21735	COG0649	NAD binding
AS200_RS21775	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AS200_RS21790	COG0302	gtp cyclohydrolase
AS200_RS21805	COG0037	tRNA processing
AS200_RS21815	COG2027	D-alanyl-D-alanine carboxypeptidase
AS200_RS21820	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AS200_RS21835	COG0393	Putative heavy-metal-binding
AS200_RS21840	COG0789	Transcriptional regulator
AS200_RS21845	COG0076	glutamate decarboxylase activity
AS200_RS21855	COG2318	DinB family
AS200_RS21860	COG1012	belongs to the aldehyde dehydrogenase family
AS200_RS21905	COG1280	lysine exporter protein (LysE YggA)
AS200_RS21915	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AS200_RS21915	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AS200_RS21920	COG3903	Transcriptional regulator
AS200_RS21920	COG3629	intracellular signal transduction
AS200_RS21960	COG1028	Short-chain dehydrogenase reductase Sdr
AS200_RS21970	COG0789	Transcriptional regulator
AS200_RS21985	COG0745	RESPONSE REGULATOR receiver
AS200_RS22005	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AS200_RS22015	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AS200_RS22020	COG0519	Catalyzes the synthesis of GMP from XMP
AS200_RS22020	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AS200_RS22030	COG0318	PFAM AMP-dependent synthetase and ligase
AS200_RS22045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS200_RS22050	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS200_RS22075	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AS200_RS22080	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AS200_RS22080	COG1754	DNA topoisomerase type I activity
AS200_RS22095	COG2890	protein-(glutamine-N5) methyltransferase activity
AS200_RS22105	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AS200_RS22115	COG1366	Belongs to the anti-sigma-factor antagonist family
AS200_RS22120	COG1205	dead DEAH box helicase
AS200_RS22120	COG1111	helicase
AS200_RS22180	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AS200_RS22185	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AS200_RS22195	COG2267	carboxylic ester hydrolase activity
AS200_RS22220	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS200_RS22240	COG0003	Pfam Anion-transporting ATPase
AS200_RS22250	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AS200_RS22255	COG1610	YqeY-like protein
AS200_RS22260	COG1408	metallophosphoesterase
AS200_RS22305	COG0701	Predicted permease
AS200_RS22330	COG1595	DNA-templated transcription, initiation
AS200_RS22350	COG0384	phenazine biosynthesis protein PhzF
AS200_RS22360	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AS200_RS22365	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AS200_RS22385	COG0693	protein deglycase activity
AS200_RS22390	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AS200_RS22395	COG1802	Transcriptional regulator
AS200_RS22400	COG1215	transferase activity, transferring glycosyl groups
AS200_RS22415	COG0737	Belongs to the 5'-nucleotidase family
AS200_RS22420	COG3547	Transposase (IS116 IS110 IS902 family)
AS200_RS22425	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AS200_RS22440	COG1131	(ABC) transporter
AS200_RS22445	COG3559	Exporter of polyketide antibiotics
AS200_RS22455	COG2197	response regulator
AS200_RS22460	COG4585	Histidine kinase
AS200_RS22465	COG2197	response regulator
AS200_RS22470	COG4585	Histidine kinase
AS200_RS22490	COG3844	kynureninase activity
AS200_RS22495	COG3483	tryptophan 2,3-dioxygenase activity
AS200_RS22505	COG0477	Major facilitator Superfamily
AS200_RS22510	COG0191	fructose-bisphosphate aldolase activity
AS200_RS22515	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AS200_RS22530	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AS200_RS22565	COG0542	response to heat
AS200_RS22590	COG4213	ABC transporter substrate-binding protein
AS200_RS22600	COG0789	Transcriptional regulator
AS200_RS22605	COG0484	heat shock protein binding
AS200_RS22610	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AS200_RS22615	COG0443	Heat shock 70 kDa protein
AS200_RS22620	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AS200_RS22625	COG2181	nitrate reductase activity
AS200_RS22625	COG0247	lactate metabolic process
AS200_RS22655	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AS200_RS22660	COG0717	Belongs to the dCTP deaminase family
AS200_RS22700	COG1278	Cold shock
AS200_RS22705	COG0513	Belongs to the DEAD box helicase family
AS200_RS22715	COG0726	polysaccharide deacetylase
AS200_RS22740	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AS200_RS22745	COG2192	nodulation
AS200_RS22760	COG0859	PFAM glycosyl transferase family 9
AS200_RS22770	COG0438	transferase activity, transferring glycosyl groups
AS200_RS22775	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AS200_RS22780	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AS200_RS22780	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AS200_RS22785	COG0859	PFAM glycosyl transferase family 9
AS200_RS22815	COG0243	molybdopterin cofactor binding
AS200_RS22825	COG2205	protein histidine kinase activity
AS200_RS22845	COG4656	Part of a membrane complex involved in electron transport
AS200_RS22875	COG4213	ABC transporter substrate-binding protein
AS200_RS22930	COG0640	Transcriptional regulator
AS200_RS22935	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
AS200_RS22945	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AS200_RS22970	COG1653	transport
AS200_RS23015	COG0583	DNA-binding transcription factor activity
AS200_RS23030	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AS200_RS23040	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AS200_RS23050	COG1741	Belongs to the pirin family
AS200_RS23060	COG1960	acyl-CoA dehydrogenase activity
AS200_RS23065	COG1362	aminopeptidase activity
AS200_RS23110	COG2226	methyltransferase
AS200_RS23120	COG0508	dehydrogenase complex catalyzes the overall conversion of
AS200_RS23125	COG0022	dehydrogenase e1 component
AS200_RS23140	COG0515	serine threonine protein kinase
AS200_RS23145	COG0515	serine threonine protein kinase
AS200_RS23165	COG1028	Short-chain dehydrogenase reductase Sdr
AS200_RS23165	COG0604	alcohol dehydrogenase
AS200_RS23165	COG3321	synthase
AS200_RS23200	COG1522	sequence-specific DNA binding
AS200_RS23205	COG1309	transcriptional regulator
AS200_RS23210	COG1250	3-hydroxyacyl-CoA dehydrogenase
AS200_RS23235	COG3396	Phenylacetate-CoA oxygenase
AS200_RS23240	COG3460	Phenylacetate-CoA oxygenase
AS200_RS23245	COG3396	Phenylacetate-CoA oxygenase
AS200_RS23250	COG2151	metal-sulfur cluster biosynthetic enzyme
AS200_RS23255	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AS200_RS23260	COG1960	acyl-CoA dehydrogenase activity
AS200_RS23285	COG1716	ATPase activity
AS200_RS23290	COG1716	ATPase activity
AS200_RS23305	COG0768	penicillin binding
AS200_RS23310	COG0515	serine threonine protein kinase
AS200_RS23315	COG3764	Sortase (surface protein transpeptidase)
AS200_RS23320	COG3764	Sortase (surface protein transpeptidase)
AS200_RS23330	COG3764	Sortase (surface protein transpeptidase)
AS200_RS23345	COG0705	Rhomboid family
AS200_RS23370	COG0515	serine threonine protein kinase
AS200_RS23390	COG4249	Peptidase C14 caspase catalytic subunit p20
AS200_RS23390	COG2319	Wd-40 repeat
AS200_RS23415	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AS200_RS23420	COG0187	DNA topoisomerase II activity
AS200_RS23425	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
AS200_RS23430	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AS200_RS23435	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AS200_RS23440	COG0592	DNA-directed DNA polymerase activity
AS200_RS23445	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AS200_RS23460	COG0706	membrane insertase activity
AS200_RS23470	COG0357	Ribosomal RNA small subunit methyltransferase G
AS200_RS23475	COG1192	Involved in chromosome partitioning
AS200_RS23490	COG3118	belongs to the thioredoxin family
AS200_RS23495	COG0492	ferredoxin-NADP+ reductase activity
AS200_RS23505	COG1595	DNA-templated transcription, initiation
AS200_RS23510	COG0515	serine threonine protein kinase
AS200_RS23510	COG2815	serine threonine protein kinase
AS200_RS23525	COG0617	tRNA 3'-terminal CCA addition
AS200_RS23555	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AS200_RS23580	COG0360	Binds together with S18 to 16S ribosomal RNA
AS200_RS23585	COG0629	single-stranded DNA binding
AS200_RS23590	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AS200_RS23595	COG0359	binds to the 23S rRNA
AS200_RS23605	COG0305	Participates in initiation and elongation during chromosome replication
AS200_RS23635	COG0626	cystathionine gamma-synthase activity
AS200_RS23640	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AS200_RS23645	COG1950	PFAM Membrane protein of
AS200_RS23650	COG0662	Cupin 2, conserved barrel domain protein
AS200_RS23675	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AS200_RS23695	COG1609	Transcriptional regulator
AS200_RS23700	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AS200_RS23705	COG1271	oxidase subunit
AS200_RS23710	COG1294	oxidase, subunit
AS200_RS23715	COG4988	ABC transporter
AS200_RS23720	COG0561	phosphatase activity
AS200_RS23735	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
AS200_RS23740	COG0789	Transcriptional regulator
AS200_RS23785	COG0561	phosphatase activity
AS200_RS23790	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AS200_RS23800	COG2837	iron assimilation
AS200_RS23840	COG0006	proline dipeptidase activity
AS200_RS23860	COG0653	protein targeting
AS200_RS23875	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AS200_RS23940	COG1595	DNA-templated transcription, initiation
AS200_RS23945	COG0318	PFAM AMP-dependent synthetase and ligase
AS200_RS23950	COG2814	Major facilitator Superfamily
AS200_RS23955	COG1309	transcriptional regulator
AS200_RS24010	COG0745	RESPONSE REGULATOR receiver
AS200_RS24015	COG2205	protein histidine kinase activity
AS200_RS24025	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AS200_RS24030	COG0477	Major facilitator Superfamily
AS200_RS24040	COG3467	pyridoxamine 5'-phosphate
AS200_RS24045	COG2353	YceI-like domain
AS200_RS24070	COG1191	sigma factor activity
AS200_RS24075	COG1191	sigma factor activity
AS200_RS24100	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AS200_RS24115	COG0433	COG0433 Predicted ATPase
AS200_RS24145	COG2372	response to copper ion
AS200_RS24150	COG1653	transport
AS200_RS24155	COG1175	transmembrane transport
AS200_RS24160	COG0395	ABC-type sugar transport system, permease component
AS200_RS24165	COG3345	alpha-galactosidase
AS200_RS24270	COG0151	Belongs to the GarS family
AS200_RS24285	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AS200_RS24295	COG2197	response regulator
AS200_RS24300	COG3851	Histidine kinase
AS200_RS24330	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AS200_RS24335	COG0047	phosphoribosylformylglycinamidine synthase activity
AS200_RS24340	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AS200_RS24360	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AS200_RS24395	COG1643	Atp-dependent helicase
AS200_RS24455	COG0513	Belongs to the DEAD box helicase family
AS200_RS24475	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AS200_RS24485	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AS200_RS24485	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AS200_RS24505	COG0667	Aldo Keto reductase
AS200_RS24515	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AS200_RS24520	COG0579	oxidoreductase
AS200_RS24550	COG1252	NADH dehydrogenase
AS200_RS24635	COG0741	lytic transglycosylase activity
AS200_RS24635	COG1196	nuclear chromosome segregation
AS200_RS24635	COG0739	heme binding
AS200_RS24640	COG0671	phosphoesterase, PA-phosphatase related
AS200_RS24645	COG0277	FAD linked oxidase domain protein
AS200_RS24660	COG0581	inorganic phosphate transmembrane transporter activity
AS200_RS24665	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AS200_RS24670	COG0306	phosphate transporter
AS200_RS24680	COG1937	Protein conserved in bacteria
AS200_RS24700	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AS200_RS24715	COG1131	(ABC) transporter
AS200_RS24730	COG0456	acetyltransferase
AS200_RS24735	COG0737	Belongs to the 5'-nucleotidase family
AS200_RS24740	COG1132	(ABC) transporter
AS200_RS24755	COG0745	RESPONSE REGULATOR receiver
AS200_RS24765	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AS200_RS24770	COG1609	Transcriptional regulator
AS200_RS24775	COG0745	RESPONSE REGULATOR receiver
AS200_RS24800	COG2897	thiosulfate sulfurtransferase activity
AS200_RS24835	COG3485	protocatechuate 3,4-dioxygenase
AS200_RS24840	COG0735	belongs to the Fur family
AS200_RS24850	COG1490	D-aminoacyl-tRNA deacylase activity
AS200_RS24860	COG4552	Acetyltransferase involved in intracellular survival and related
AS200_RS24865	COG2188	Transcriptional regulator
AS200_RS24875	COG2186	Transcriptional regulator
AS200_RS24880	COG0546	phosphoglycolate phosphatase activity
AS200_RS24900	COG1309	transcriptional regulator
AS200_RS24905	COG3973	AAA domain
AS200_RS24915	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AS200_RS24960	COG0438	transferase activity, transferring glycosyl groups
AS200_RS24970	COG2207	Transcriptional regulator
AS200_RS24970	COG1917	Cupin 2, conserved barrel domain protein
AS200_RS24990	COG0588	phosphoglycerate mutase activity
AS200_RS24995	COG0222	ribosome binding
AS200_RS25000	COG0222	ribosome binding
AS200_RS25030	COG5002	protein histidine kinase activity
AS200_RS25045	COG1329	Transcriptional regulator
AS200_RS25050	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AS200_RS25055	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AS200_RS25060	COG0215	cysteine-tRNA ligase activity
AS200_RS25085	COG3842	ATPase activity
AS200_RS25110	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AS200_RS25125	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AS200_RS25130	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AS200_RS25135	COG2175	clavaminate synthase activity
AS200_RS25150	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AS200_RS25155	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS200_RS25160	COG3321	synthase
AS200_RS25160	COG1028	Short-chain dehydrogenase reductase Sdr
AS200_RS25160	COG0604	alcohol dehydrogenase
AS200_RS25200	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AS200_RS25205	COG0318	PFAM AMP-dependent synthetase and ligase
AS200_RS25220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AS200_RS25225	COG1914	H( )-stimulated, divalent metal cation uptake system
AS200_RS25235	COG3903	Transcriptional regulator
AS200_RS25235	COG3629	intracellular signal transduction
AS200_RS25245	COG4585	Histidine kinase
AS200_RS25250	COG2197	response regulator
AS200_RS25365	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AS200_RS25385	COG3300	MHYT domain
AS200_RS25385	COG5001	Diguanylate cyclase
AS200_RS25395	COG1105	Belongs to the carbohydrate kinase PfkB family
AS200_RS25430	COG0463	Glycosyl transferase, family 2
AS200_RS25450	COG0459	protein refolding
AS200_RS25470	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AS200_RS25475	COG1737	Transcriptional regulator
AS200_RS25505	COG3142	Participates in the control of copper homeostasis
AS200_RS25510	COG3973	AAA domain
AS200_RS25525	COG1061	Type III restriction enzyme res subunit
AS200_RS25530	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AS200_RS25555	COG1278	Cold shock
AS200_RS25565	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
AS200_RS25570	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AS200_RS25580	COG2814	Major facilitator Superfamily
AS200_RS25610	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AS200_RS25620	COG2252	PERMEase
AS200_RS25650	COG0667	Aldo Keto reductase
AS200_RS25685	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AS200_RS25690	COG0596	Alpha beta hydrolase
AS200_RS25695	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AS200_RS25725	COG0277	FAD linked oxidase domain protein
AS200_RS25725	COG0247	lactate metabolic process
AS200_RS25730	COG1132	(ABC) transporter
AS200_RS25735	COG5006	permease, DMT superfamily
AS200_RS25750	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AS200_RS25765	COG0318	PFAM AMP-dependent synthetase and ligase
AS200_RS25780	COG0259	pyridoxamine-phosphate oxidase activity
AS200_RS25800	COG4821	SIS domain
AS200_RS25810	COG0596	Alpha beta hydrolase
AS200_RS25810	COG2945	thiolester hydrolase activity
AS200_RS25860	COG1595	DNA-templated transcription, initiation
AS200_RS25875	COG0318	PFAM AMP-dependent synthetase and ligase
AS200_RS25885	COG1960	acyl-CoA dehydrogenase activity
AS200_RS25890	COG1960	acyl-CoA dehydrogenase activity
AS200_RS25905	COG1028	Short-chain dehydrogenase reductase Sdr
AS200_RS25910	COG1960	acyl-CoA dehydrogenase activity
AS200_RS25915	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AS200_RS25935	COG1024	Enoyl-CoA hydratase
AS200_RS25945	COG1231	oxidoreductase activity
AS200_RS25950	COG2072	flavoprotein involved in K transport
AS200_RS25980	COG0259	pyridoxamine-phosphate oxidase activity
AS200_RS25995	COG1960	acyl-CoA dehydrogenase activity
AS200_RS26010	COG1309	transcriptional regulator
AS200_RS26020	COG0515	serine threonine protein kinase
AS200_RS26020	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AS200_RS26030	COG1024	Enoyl-CoA hydratase
AS200_RS26045	COG0318	PFAM AMP-dependent synthetase and ligase
AS200_RS26075	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AS200_RS26105	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AS200_RS26160	COG1686	Belongs to the peptidase S11 family
AS200_RS26175	COG0386	Belongs to the glutathione peroxidase family
AS200_RS26190	COG0330	HflC and HflK could
AS200_RS26210	COG0489	protein tyrosine kinase activity
AS200_RS26245	COG1404	Belongs to the peptidase S8 family
AS200_RS26265	COG0582	viral genome integration into host DNA
AS200_RS26275	COG1414	Transcriptional regulator
AS200_RS26295	COG1846	Transcriptional regulator
AS200_RS26300	COG3384	dioxygenase
AS200_RS26305	COG1247	-acetyltransferase
AS200_RS26310	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AS200_RS26325	COG0477	Major facilitator Superfamily
AS200_RS26330	COG1349	DNA-binding transcription factor activity
AS200_RS26340	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AS200_RS26340	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AS200_RS26340	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AS200_RS26355	COG1376	ErfK ybiS ycfS ynhG family protein
AS200_RS26360	COG3191	aminopeptidase activity
AS200_RS26375	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AS200_RS26385	COG1970	mechanosensitive ion channel activity
AS200_RS26395	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AS200_RS26420	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AS200_RS26425	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AS200_RS26435	COG0315	cyclic pyranopterin monophosphate synthase activity
AS200_RS26440	COG0521	Mo-molybdopterin cofactor biosynthetic process
AS200_RS26440	COG0315	cyclic pyranopterin monophosphate synthase activity
AS200_RS26460	COG0454	-acetyltransferase
AS200_RS26475	COG2072	flavoprotein involved in K transport
AS200_RS26480	COG2267	carboxylic ester hydrolase activity
AS200_RS26485	COG1028	Short-chain dehydrogenase reductase Sdr
AS200_RS26495	COG4946	Tricorn protease homolog
AS200_RS26495	COG0793	Belongs to the peptidase S41A family
AS200_RS26505	COG2409	Drug exporters of the RND superfamily
AS200_RS26525	COG0442	prolyl-tRNA aminoacylation
AS200_RS26545	COG1131	(ABC) transporter
AS200_RS26570	COG1764	response to oxidative stress
AS200_RS26580	COG1122	ATPase activity
AS200_RS26590	COG0310	cobalt ion transport
AS200_RS26605	COG0768	penicillin binding
AS200_RS26625	COG0084	hydrolase, TatD family'
AS200_RS26630	COG3584	3D domain protein
AS200_RS26630	COG3583	domain protein
AS200_RS26635	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AS200_RS26640	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AS200_RS26650	COG0488	(ABC) transporter
AS200_RS26690	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AS200_RS26700	COG2197	response regulator
AS200_RS26710	COG4106	trans-aconitate 2-methyltransferase activity
AS200_RS26720	COG1309	transcriptional regulator
AS200_RS26730	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AS200_RS26745	COG0193	aminoacyl-tRNA hydrolase activity
AS200_RS26750	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AS200_RS26755	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AS200_RS26760	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AS200_RS26775	COG4585	Histidine kinase
AS200_RS26805	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AS200_RS26815	COG0477	Major facilitator Superfamily
AS200_RS26820	COG1136	(ABC) transporter
AS200_RS26825	COG0577	efflux transmembrane transporter activity
AS200_RS26900	COG0148	phosphopyruvate hydratase activity
AS200_RS26915	COG1252	NADH dehydrogenase
AS200_RS26920	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AS200_RS26925	COG0577	efflux transmembrane transporter activity
AS200_RS26930	COG1136	(ABC) transporter
AS200_RS26995	COG0183	Belongs to the thiolase family
AS200_RS27000	COG2755	lipolytic protein G-D-S-L family
AS200_RS27015	COG4221	oxidoreductase activity
AS200_RS27025	COG2986	histidine ammonia-lyase
AS200_RS27065	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AS200_RS27070	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AS200_RS27080	COG1228	amidohydrolase
AS200_RS27090	COG1191	sigma factor activity
AS200_RS27095	COG1366	Belongs to the anti-sigma-factor antagonist family
AS200_RS27130	COG3104	oligopeptide transport
AS200_RS27135	COG0745	RESPONSE REGULATOR receiver
AS200_RS27140	COG2205	protein histidine kinase activity
AS200_RS27185	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AS200_RS27205	COG1316	TRANSCRIPTIONal
AS200_RS27215	COG1316	TRANSCRIPTIONal
AS200_RS27230	COG1316	TRANSCRIPTIONal
AS200_RS27235	COG1316	TRANSCRIPTIONal
AS200_RS27240	COG1316	TRANSCRIPTIONal
AS200_RS27265	COG0778	Nitroreductase
AS200_RS27265	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
AS200_RS27270	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AS200_RS27305	COG1620	l-lactate permease
AS200_RS27310	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AS200_RS27320	COG1482	cell wall glycoprotein biosynthetic process
AS200_RS27330	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AS200_RS27370	COG0714	Associated with various cellular activities
AS200_RS27390	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AS200_RS27395	COG0745	RESPONSE REGULATOR receiver
AS200_RS27400	COG5000	phosphorelay sensor kinase activity
AS200_RS27400	COG5002	protein histidine kinase activity
AS200_RS27405	COG0823	Involved in the tonB-independent uptake of proteins
AS200_RS27415	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AS200_RS27420	COG2197	response regulator
AS200_RS27425	COG3214	Protein conserved in bacteria
AS200_RS27435	COG0653	protein targeting
AS200_RS27455	COG2902	Dehydrogenase
AS200_RS27460	COG1134	teichoic acid transport
AS200_RS27490	COG1846	Transcriptional regulator
AS200_RS27495	COG1764	response to oxidative stress
AS200_RS27505	COG1216	Glycosyl transferase, family 2
AS200_RS27510	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AS200_RS27515	COG1216	Glycosyl transferase, family 2
AS200_RS27520	COG0395	ABC-type sugar transport system, permease component
AS200_RS27525	COG1175	transmembrane transport
AS200_RS27530	COG1653	transport
AS200_RS27540	COG0515	serine threonine protein kinase
AS200_RS27545	COG0515	serine threonine protein kinase
AS200_RS27550	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AS200_RS27565	COG2884	Cell division ATP-binding protein ftsE
AS200_RS27570	COG2177	Part of the ABC transporter FtsEX involved in
AS200_RS27575	COG0793	Belongs to the peptidase S41A family
AS200_RS27580	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AS200_RS27590	COG1472	Belongs to the glycosyl hydrolase 3 family
AS200_RS27595	COG1609	Transcriptional regulator
AS200_RS27600	COG1501	Belongs to the glycosyl hydrolase 31 family
AS200_RS27605	COG0395	ABC-type sugar transport system, permease component
AS200_RS27610	COG4209	transmembrane transport
AS200_RS27630	COG2223	nitrite transmembrane transporter activity
AS200_RS27660	COG3973	AAA domain
AS200_RS27670	COG0776	regulation of translation
AS200_RS27675	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AS200_RS27680	COG1678	Uncharacterized ACR, COG1678
AS200_RS27690	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AS200_RS27705	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AS200_RS27785	COG3185	4-Hydroxyphenylpyruvate dioxygenase
AS200_RS27815	COG0277	FAD linked oxidase domain protein
AS200_RS27850	COG1335	isochorismatase
AS200_RS27860	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AS200_RS27870	COG1113	amino acid transport
AS200_RS27895	COG1234	tRNA 3'-trailer cleavage
AS200_RS27900	COG1263	PTS System
AS200_RS27905	COG1263	PTS System
AS200_RS27910	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AS200_RS27915	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AS200_RS27925	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AS200_RS27975	COG4555	ABC transporter
AS200_RS27990	COG2733	membrane
AS200_RS27995	COG2814	Major facilitator Superfamily
AS200_RS28005	COG0071	Belongs to the small heat shock protein (HSP20) family
AS200_RS28025	COG0187	DNA topoisomerase II activity
AS200_RS28045	COG1074	ATP-dependent DNA helicase activity
AS200_RS28075	COG0270	DNA (cytosine-5-)-methyltransferase activity
AS200_RS28095	COG2814	Major facilitator Superfamily
AS200_RS28105	COG3764	Sortase (surface protein transpeptidase)
AS200_RS28125	COG4455	Protein of avirulence locus involved in temperature-dependent protein secretion
AS200_RS28125	COG0706	membrane insertase activity
AS200_RS28135	COG4702	Belongs to the UPF0303 family
AS200_RS28140	COG0673	inositol 2-dehydrogenase activity
AS200_RS28185	COG2186	Transcriptional regulator
AS200_RS28205	COG3397	chitin binding
AS200_RS28235	COG1126	abc transporter atp-binding protein
AS200_RS28240	COG0765	amino acid transport
AS200_RS28245	COG0765	amino acid transport
AS200_RS28250	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AS200_RS28265	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AS200_RS28280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS200_RS28325	COG0406	alpha-ribazole phosphatase activity
AS200_RS28350	COG0745	RESPONSE REGULATOR receiver
AS200_RS28360	COG3979	chitinase
AS200_RS28370	COG0395	ABC-type sugar transport system, permease component
AS200_RS28400	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AS200_RS28405	COG4977	sequence-specific DNA binding
AS200_RS28415	COG0589	response to stress
AS200_RS28420	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AS200_RS28450	COG3486	L-lysine 6-monooxygenase (NADPH) activity
AS200_RS28470	COG1960	acyl-CoA dehydrogenase activity
AS200_RS28485	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AS200_RS28490	COG1309	transcriptional regulator
AS200_RS28500	COG1946	Acyl-CoA thioesterase
AS200_RS28525	COG0028	Belongs to the TPP enzyme family
AS200_RS28530	COG2356	endonuclease I
AS200_RS28535	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AS200_RS28570	COG1472	Belongs to the glycosyl hydrolase 3 family
AS200_RS28575	COG0583	DNA-binding transcription factor activity
AS200_RS28585	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AS200_RS28605	COG1846	Transcriptional regulator
AS200_RS28605	COG0456	acetyltransferase
AS200_RS28610	COG1609	Transcriptional regulator
AS200_RS28615	COG0673	inositol 2-dehydrogenase activity
AS200_RS28630	COG1869	D-ribose catabolic process
AS200_RS28635	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AS200_RS28645	COG1129	ABC transporter
AS200_RS28650	COG1609	Transcriptional regulator
AS200_RS28680	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AS200_RS28715	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AS200_RS28725	COG3718	enzyme involved in inositol metabolism
AS200_RS28730	COG3962	Belongs to the TPP enzyme family
AS200_RS28785	COG0492	ferredoxin-NADP+ reductase activity
AS200_RS28810	COG0438	transferase activity, transferring glycosyl groups
AS200_RS28830	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AS200_RS28835	COG0438	transferase activity, transferring glycosyl groups
AS200_RS28875	COG2304	oxidoreductase activity
AS200_RS28885	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AS200_RS28900	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AS200_RS28905	COG0629	single-stranded DNA binding
AS200_RS28945	COG1136	(ABC) transporter
AS200_RS28945	COG0577	efflux transmembrane transporter activity
AS200_RS28965	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AS200_RS29000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AS200_RS29015	COG1486	melibiose metabolic process
AS200_RS29020	COG0395	ABC-type sugar transport system, permease component
AS200_RS29025	COG1175	transmembrane transport
AS200_RS29035	COG1940	carbohydrate kinase activity
AS200_RS29040	COG0668	transmembrane transport
AS200_RS29055	COG1136	(ABC) transporter
AS200_RS29085	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AS200_RS29090	COG1846	Transcriptional regulator
AS200_RS29100	COG0697	spore germination
AS200_RS29110	COG0583	DNA-binding transcription factor activity
AS200_RS29195	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AS200_RS29220	COG1349	DNA-binding transcription factor activity
AS200_RS29225	COG3842	ATPase activity
AS200_RS29230	COG0395	ABC-type sugar transport system, permease component
AS200_RS29235	COG1175	transmembrane transport
AS200_RS29240	COG1653	transport
AS200_RS29245	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AS200_RS29250	COG0588	phosphoglycerate mutase activity
AS200_RS29260	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS200_RS29265	COG1116	anion transmembrane transporter activity
AS200_RS29270	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AS200_RS29275	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AS200_RS29300	COG0515	serine threonine protein kinase
AS200_RS29305	COG1113	amino acid transport
AS200_RS29310	COG0698	ribose 5-phosphate isomerase
AS200_RS29320	COG4552	Acetyltransferase involved in intracellular survival and related
AS200_RS29335	COG3594	Acyltransferase
AS200_RS29355	COG0544	peptidyl-prolyl cis-trans isomerase activity
AS200_RS29360	COG0740	serine-type endopeptidase activity
AS200_RS29365	COG0740	serine-type endopeptidase activity
AS200_RS29370	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AS200_RS29380	COG0525	valine-tRNA ligase activity
AS200_RS29385	COG0285	dihydrofolate synthase activity
AS200_RS29395	COG0105	UTP biosynthetic process
AS200_RS29400	COG1077	Cell shape determining protein MreB Mrl
AS200_RS29415	COG0768	penicillin binding
AS200_RS29420	COG0772	Belongs to the SEDS family
AS200_RS29460	COG1530	ribonuclease E activity
AS200_RS29465	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AS200_RS29470	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AS200_RS29475	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AS200_RS29480	COG3540	Alkaline phosphatase
AS200_RS29510	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AS200_RS29520	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AS200_RS29535	COG0501	Belongs to the peptidase M48B family
AS200_RS29540	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AS200_RS29550	COG0799	negative regulation of ribosome biogenesis
AS200_RS29555	COG0588	phosphoglycerate mutase activity
AS200_RS29570	COG0477	Major facilitator Superfamily
AS200_RS29585	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AS200_RS29595	COG0495	leucyl-tRNA aminoacylation
AS200_RS29605	COG1307	EDD domain protein, DegV family
AS200_RS29610	COG1555	photosystem II stabilization
AS200_RS29665	COG2162	N-hydroxyarylamine O-acetyltransferase activity
AS200_RS29680	COG0268	Binds directly to 16S ribosomal RNA
AS200_RS29685	COG0481	GTPase activity
AS200_RS29725	COG1420	regulation of RNA biosynthetic process
AS200_RS29730	COG0484	heat shock protein binding
AS200_RS29755	COG0793	Belongs to the peptidase S41A family
AS200_RS29755	COG4946	Tricorn protease homolog
AS200_RS29760	COG0537	adenosine 5'-monophosphoramidase activity
AS200_RS29765	COG1234	tRNA 3'-trailer cleavage
AS200_RS29770	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AS200_RS29785	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AS200_RS29790	COG4948	Mandelate Racemase Muconate Lactonizing
AS200_RS29795	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AS200_RS29805	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AS200_RS29815	COG2315	Protein conserved in bacteria
AS200_RS29855	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AS200_RS29875	COG2723	6-phospho-beta-galactosidase activity
AS200_RS29890	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AS200_RS29900	COG2409	Drug exporters of the RND superfamily
AS200_RS29905	COG4585	Histidine kinase
AS200_RS29920	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AS200_RS29925	COG4608	Belongs to the ABC transporter superfamily
AS200_RS29930	COG0444	Belongs to the ABC transporter superfamily
AS200_RS29940	COG0747	negative chemotaxis
AS200_RS29945	COG2186	Transcriptional regulator
AS200_RS29975	COG1131	(ABC) transporter
AS200_RS29980	COG4585	Histidine kinase
AS200_RS29985	COG2197	response regulator
AS200_RS30010	COG1381	Involved in DNA repair and RecF pathway recombination
AS200_RS30015	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AS200_RS30030	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AS200_RS30035	COG1121	(ABC) transporter
AS200_RS30040	COG0803	Belongs to the bacterial solute-binding protein 9 family
AS200_RS30040	COG3443	Belongs to the bacterial solute-binding protein 9 family
AS200_RS30045	COG0423	glycine-tRNA ligase activity
AS200_RS30055	COG0667	Aldo Keto reductase
AS200_RS30075	COG0477	Major facilitator Superfamily
AS200_RS30105	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
AS200_RS30110	COG1940	carbohydrate kinase activity
AS200_RS30110	COG1846	Transcriptional regulator
AS200_RS30115	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AS200_RS30115	COG0574	Belongs to the PEP-utilizing enzyme family
AS200_RS30145	COG4221	oxidoreductase activity
AS200_RS30150	COG1028	Short-chain dehydrogenase reductase Sdr
AS200_RS30155	COG1309	transcriptional regulator
AS200_RS30165	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AS200_RS30165	COG2146	nitrite reductase [NAD(P)H] activity
AS200_RS30170	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AS200_RS30175	COG3896	Chloramphenicol phosphotransferase-like protein
AS200_RS30190	COG0431	NADPH-dependent FMN reductase
AS200_RS30205	COG0243	molybdopterin cofactor binding
AS200_RS30210	COG2949	membrane
AS200_RS30220	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AS200_RS30230	COG0358	DNA primase activity
AS200_RS30235	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AS200_RS30250	COG1070	Carbohydrate kinase
AS200_RS30285	COG1609	Transcriptional regulator
AS200_RS30290	COG1621	beta-fructofuranosidase activity
AS200_RS30300	COG1175	transmembrane transport
AS200_RS30305	COG0395	ABC-type sugar transport system, permease component
AS200_RS30345	COG1077	Cell shape determining protein MreB Mrl
AS200_RS30370	COG0825	malonyl-CoA metabolic process
AS200_RS30370	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AS200_RS30375	COG0318	PFAM AMP-dependent synthetase and ligase
AS200_RS30415	COG4981	capsule polysaccharide biosynthetic process
AS200_RS30445	COG1414	Transcriptional regulator
AS200_RS30475	COG0730	response to heat
AS200_RS30505	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AS200_RS30515	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AS200_RS30525	COG2160	L-arabinose isomerase activity
AS200_RS30530	COG0235	Class ii aldolase
AS200_RS30540	COG4214	carbohydrate transport
AS200_RS30545	COG1129	ABC transporter
AS200_RS30580	COG2130	NADP-dependent
AS200_RS30585	COG1764	response to oxidative stress
AS200_RS30590	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AS200_RS30650	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AS200_RS30655	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AS200_RS30660	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AS200_RS30675	COG1741	Belongs to the pirin family
AS200_RS30690	COG0789	Transcriptional regulator
AS200_RS30705	COG1309	transcriptional regulator
AS200_RS30710	COG0477	Major facilitator Superfamily
AS200_RS30720	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AS200_RS30770	COG1358	cellular component organization or biogenesis
AS200_RS30785	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AS200_RS30830	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AS200_RS30845	COG2259	Doxx family
AS200_RS30885	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AS200_RS30910	COG4122	O-methyltransferase activity
AS200_RS30915	COG0477	Major facilitator Superfamily
AS200_RS30925	COG2124	cytochrome p450
AS200_RS30930	COG0183	Belongs to the thiolase family
AS200_RS30935	COG3619	membrane
AS200_RS30960	COG3845	ABC transporter
AS200_RS31045	COG0494	nUDIX hydrolase
AS200_RS31070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS200_RS31085	COG1309	transcriptional regulator
AS200_RS31090	COG0438	transferase activity, transferring glycosyl groups
AS200_RS31115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS200_RS31125	COG0860	N-Acetylmuramoyl-L-alanine amidase
AS200_RS31135	COG0477	Major facilitator Superfamily
AS200_RS31140	COG0183	Belongs to the thiolase family
AS200_RS31160	COG2197	response regulator
AS200_RS31170	COG4585	Histidine kinase
AS200_RS31180	COG1131	(ABC) transporter
AS200_RS31185	COG2030	dehydratase
AS200_RS31195	COG1028	Short-chain dehydrogenase reductase Sdr
AS200_RS31205	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AS200_RS31220	COG0800	Aldolase
AS200_RS31225	COG3022	response to hydroperoxide
AS200_RS31280	COG3629	intracellular signal transduction
AS200_RS31280	COG3903	Transcriptional regulator
AS200_RS31305	COG0791	NLP P60 protein
AS200_RS31375	COG3903	Transcriptional regulator
AS200_RS31375	COG3629	intracellular signal transduction
AS200_RS31390	COG0318	PFAM AMP-dependent synthetase and ligase
AS200_RS31410	COG0667	Aldo Keto reductase
AS200_RS31415	COG1136	(ABC) transporter
AS200_RS31425	COG1686	Belongs to the peptidase S11 family
AS200_RS31435	COG3540	Alkaline phosphatase
AS200_RS31445	COG2814	Major facilitator Superfamily
AS200_RS31450	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AS200_RS31475	COG0672	)-iron permease
AS200_RS31480	COG2837	iron assimilation
AS200_RS31485	COG2822	iron ion transport
AS200_RS31535	COG1994	Peptidase M50
AS200_RS31555	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AS200_RS31560	COG0477	Major facilitator Superfamily
AS200_RS31575	COG2814	Major facilitator Superfamily
AS200_RS31585	COG2132	Multicopper oxidase
AS200_RS31605	COG1959	2 iron, 2 sulfur cluster binding
AS200_RS31615	COG0174	glutamine synthetase
AS200_RS31635	COG3511	phospholipase C
AS200_RS31645	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AS200_RS31660	COG1228	amidohydrolase
AS200_RS31670	COG1609	Transcriptional regulator
AS200_RS31680	COG1175	transmembrane transport
AS200_RS31685	COG3833	ABC-type maltose transport systems, permease component
AS200_RS31690	COG0366	Alpha amylase catalytic
AS200_RS31725	COG1309	transcriptional regulator
AS200_RS31760	COG2197	response regulator
AS200_RS31775	COG0745	RESPONSE REGULATOR receiver
AS200_RS31830	COG2201	protein-glutamate methylesterase activity
AS200_RS31860	COG0501	Belongs to the peptidase M48B family
AS200_RS31870	COG0174	glutamine synthetase
AS200_RS31890	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AS200_RS31895	COG0321	lipoyl(octanoyl) transferase activity
AS200_RS31920	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AS200_RS31955	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AS200_RS31965	COG0508	dehydrogenase complex catalyzes the overall conversion of
AS200_RS31970	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AS200_RS31975	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AS200_RS31990	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AS200_RS32005	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AS200_RS32005	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AS200_RS32010	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AS200_RS32030	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AS200_RS32035	COG2226	methyltransferase
AS200_RS32060	COG2197	response regulator
AS200_RS32085	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AS200_RS32085	COG0515	serine threonine protein kinase
AS200_RS32090	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AS200_RS32110	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AS200_RS32120	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AS200_RS32125	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AS200_RS32135	COG1376	ErfK ybiS ycfS ynhG family protein
AS200_RS32145	COG1845	cytochrome c oxidase, subunit III
AS200_RS32150	COG2010	Cytochrome c
AS200_RS32155	COG0723	plastoquinol--plastocyanin reductase activity
AS200_RS32160	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AS200_RS32165	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AS200_RS32170	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AS200_RS32215	COG0534	Mate efflux family protein
AS200_RS32235	COG1022	Amp-dependent synthetase and ligase
AS200_RS32250	COG0003	Pfam Anion-transporting ATPase
AS200_RS32260	COG1940	carbohydrate kinase activity
AS200_RS32285	COG4585	Histidine kinase
AS200_RS32290	COG2197	response regulator
AS200_RS32295	COG0205	6-phosphofructokinase activity
AS200_RS32300	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AS200_RS32310	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AS200_RS32315	COG0243	molybdopterin cofactor binding
AS200_RS32320	COG2193	ferroxidase activity
AS200_RS32325	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AS200_RS32335	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AS200_RS32340	COG0515	serine threonine protein kinase
AS200_RS32340	COG2815	serine threonine protein kinase
AS200_RS32345	COG2022	thiamine diphosphate biosynthetic process
AS200_RS32355	COG2022	thiamine diphosphate biosynthetic process
AS200_RS32355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AS200_RS32370	COG0352	thiamine-phosphate diphosphorylase activity
AS200_RS32395	COG1309	transcriptional regulator
AS200_RS32405	COG1121	(ABC) transporter
AS200_RS32415	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AS200_RS32435	COG0714	Associated with various cellular activities
AS200_RS32445	COG0275	rRNA processing
AS200_RS32460	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AS200_RS32470	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AS200_RS32475	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AS200_RS32485	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AS200_RS32490	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AS200_RS32495	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AS200_RS32500	COG1496	oxidoreductase activity
AS200_RS32510	COG1799	cell septum assembly
AS200_RS32520	COG3599	regulation of cell shape
AS200_RS32525	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AS200_RS32535	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AS200_RS32595	COG0587	DNA-directed DNA polymerase activity
AS200_RS32600	COG1432	Conserved Protein
AS200_RS32620	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AS200_RS32640	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AS200_RS32645	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AS200_RS32650	COG0131	Imidazoleglycerol-phosphate dehydratase
AS200_RS32660	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AS200_RS32665	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AS200_RS32670	COG0251	oxidation-reduction process
AS200_RS32675	COG0107	imidazoleglycerol-phosphate synthase activity
AS200_RS32695	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AS200_RS32725	COG0134	indole-3-glycerol-phosphate synthase activity
AS200_RS32730	COG0133	tryptophan synthase activity
AS200_RS32735	COG0159	tryptophan synthase activity
AS200_RS32745	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AS200_RS32760	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AS200_RS32780	COG1397	ADP-ribosylglycohydrolase
AS200_RS32790	COG0069	glutamate synthase activity
AS200_RS32790	COG0070	glutamate synthase
AS200_RS32790	COG0067	glutamate synthase
AS200_RS32805	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AS200_RS32810	COG1215	transferase activity, transferring glycosyl groups
AS200_RS32830	COG2304	oxidoreductase activity
AS200_RS32835	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AS200_RS32845	COG1960	acyl-CoA dehydrogenase activity
AS200_RS32855	COG1309	transcriptional regulator
AS200_RS32860	COG0183	Belongs to the thiolase family
AS200_RS32880	COG1024	Enoyl-CoA hydratase
AS200_RS32890	COG1028	Short-chain dehydrogenase reductase Sdr
AS200_RS32900	COG1605	Chorismate mutase
AS200_RS32900	COG0287	Prephenate dehydrogenase
AS200_RS32905	COG0745	RESPONSE REGULATOR receiver
AS200_RS32925	COG0737	Belongs to the 5'-nucleotidase family
AS200_RS32955	COG0411	ABC transporter
AS200_RS32965	COG0559	Belongs to the binding-protein-dependent transport system permease family
AS200_RS32985	COG2050	protein possibly involved in aromatic compounds catabolism
AS200_RS33020	COG1643	Atp-dependent helicase
AS200_RS33025	COG2226	methyltransferase
AS200_RS33025	COG1073	alpha beta
AS200_RS33030	COG0539	negative regulation of cytoplasmic translation
AS200_RS33040	COG0237	dephospho-CoA kinase activity
AS200_RS33075	COG2267	carboxylic ester hydrolase activity
AS200_RS33080	COG1802	Transcriptional regulator
AS200_RS33085	COG1953	Uracil, thiamine, allantoin
AS200_RS33115	COG2197	response regulator
AS200_RS33170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS200_RS33175	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AS200_RS33210	COG0598	Magnesium transport protein CorA
AS200_RS33215	COG2226	methyltransferase
AS200_RS33225	COG2313	pseudouridylate synthase activity
AS200_RS33235	COG1063	alcohol dehydrogenase
AS200_RS33240	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AS200_RS33245	COG0584	glycerophosphoryl diester phosphodiesterase
AS200_RS33255	COG0556	nucleotide-excision repair
AS200_RS33275	COG0387	Pfam Sodium calcium exchanger
AS200_RS33280	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AS200_RS33290	COG0765	amino acid transport
AS200_RS33295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AS200_RS33310	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AS200_RS33335	COG0322	excinuclease ABC activity
AS200_RS33340	COG1660	Displays ATPase and GTPase activities
AS200_RS33345	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AS200_RS33350	COG1481	regulation of sporulation
AS200_RS33360	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AS200_RS33365	COG0126	phosphoglycerate kinase activity
AS200_RS33370	COG0149	triose-phosphate isomerase activity
AS200_RS33375	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AS200_RS33390	COG0166	Belongs to the GPI family
AS200_RS33400	COG1136	(ABC) transporter
AS200_RS33405	COG1695	Transcriptional regulator
AS200_RS33410	COG1653	transport
AS200_RS33415	COG0366	Alpha amylase catalytic
AS200_RS33425	COG1175	transmembrane transport
AS200_RS33430	COG0395	ABC-type sugar transport system, permease component
AS200_RS33435	COG0363	glucosamine-6-phosphate deaminase activity
AS200_RS33450	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AS200_RS33460	COG0109	protoheme IX farnesyltransferase activity
AS200_RS33485	COG1131	(ABC) transporter
AS200_RS33490	COG2746	aminoglycoside 3-N-acetyltransferase activity
AS200_RS33505	COG0719	Fe-S assembly protein
AS200_RS33515	COG0396	ATPase activity
AS200_RS33520	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AS200_RS33525	COG0822	iron-sulfur transferase activity
AS200_RS33530	COG2151	metal-sulfur cluster biosynthetic enzyme
AS200_RS33540	COG2076	Multidrug Resistance protein
AS200_RS33545	COG3226	Transcriptional regulator
AS200_RS33570	COG2171	N-acyltransferase activity
AS200_RS33580	COG1595	DNA-templated transcription, initiation
AS200_RS33590	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AS200_RS33610	COG1959	2 iron, 2 sulfur cluster binding
AS200_RS33610	COG1295	ribonuclease BN
AS200_RS33660	COG1802	Transcriptional regulator
AS200_RS33675	COG1063	alcohol dehydrogenase
AS200_RS33680	COG0395	ABC-type sugar transport system, permease component
AS200_RS33695	COG1349	DNA-binding transcription factor activity
AS200_RS33700	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AS200_RS33705	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AS200_RS33720	COG1234	tRNA 3'-trailer cleavage
AS200_RS33725	COG1802	Transcriptional regulator
AS200_RS33740	COG1175	transmembrane transport
AS200_RS33745	COG0395	ABC-type sugar transport system, permease component
AS200_RS33765	COG1653	transport
AS200_RS33770	COG2755	lipolytic protein G-D-S-L family
AS200_RS33780	COG4677	pectinesterase activity
AS200_RS33785	COG4677	pectinesterase activity
AS200_RS33795	COG4733	cellulase activity
AS200_RS33815	COG1595	DNA-templated transcription, initiation
AS200_RS33820	COG2252	PERMEase
AS200_RS33825	COG0768	penicillin binding
AS200_RS33835	COG1414	Transcriptional regulator
AS200_RS33850	COG0477	Major facilitator Superfamily
AS200_RS33870	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AS200_RS33875	COG5285	phytanoyl-CoA dioxygenase
AS200_RS33880	COG1917	Cupin 2, conserved barrel domain protein
AS200_RS33885	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AS200_RS33890	COG0456	acetyltransferase
AS200_RS33895	COG2318	DinB family
AS200_RS33900	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AS200_RS33905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AS200_RS33910	COG0765	amino acid transport
AS200_RS33920	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AS200_RS33975	COG1797	cobyrinic acid a,c-diamide synthase activity
AS200_RS33995	COG1492	cobalamin metabolic process
AS200_RS34000	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AS200_RS34030	COG0235	Class ii aldolase
AS200_RS34045	COG0488	(ABC) transporter
AS200_RS34095	COG3387	PFAM Glycoside hydrolase 15-related
AS200_RS34110	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AS200_RS34130	COG1063	alcohol dehydrogenase
AS200_RS34140	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AS200_RS34160	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AS200_RS34165	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AS200_RS34175	COG0395	ABC-type sugar transport system, permease component
AS200_RS34210	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AS200_RS34240	COG2186	Transcriptional regulator
AS200_RS34255	COG0588	phosphoglycerate mutase activity
AS200_RS34260	COG3830	Belongs to the UPF0237 family
AS200_RS34260	COG0560	Phosphoserine phosphatase
AS200_RS34270	COG1131	(ABC) transporter
AS200_RS34270	COG0842	Transport permease protein
AS200_RS34270	COG1716	ATPase activity
AS200_RS34280	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AS200_RS34285	COG4221	oxidoreductase activity
AS200_RS34295	COG2197	response regulator
AS200_RS34310	COG1119	ATPase activity
AS200_RS34330	COG1881	PFAM PEBP family protein
AS200_RS34340	COG2094	Belongs to the DNA glycosylase MPG family
AS200_RS34375	COG0647	UMP catabolic process
AS200_RS34380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS200_RS34385	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS200_RS34390	COG1120	ATPase activity
AS200_RS34410	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AS200_RS34415	COG0497	DNA recombination
AS200_RS34430	COG3387	PFAM Glycoside hydrolase 15-related
AS200_RS34435	COG0504	CTP synthase activity
AS200_RS34440	COG0494	nUDIX hydrolase
AS200_RS34450	COG0686	Belongs to the AlaDH PNT family
AS200_RS34465	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AS200_RS34470	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AS200_RS34475	COG1187	pseudouridine synthase activity
AS200_RS34485	COG0494	nUDIX hydrolase
AS200_RS34495	COG3541	Predicted nucleotidyltransferase
AS200_RS34530	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AS200_RS34540	COG1160	GTP binding
AS200_RS34595	COG0671	phosphoesterase, PA-phosphatase related
AS200_RS34605	COG0477	Major facilitator Superfamily
AS200_RS34610	COG1960	acyl-CoA dehydrogenase activity
AS200_RS34615	COG1799	cell septum assembly
AS200_RS34635	COG0330	HflC and HflK could
AS200_RS34655	COG0587	DNA-directed DNA polymerase activity
AS200_RS34660	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AS200_RS34665	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AS200_RS34665	COG0662	Cupin 2, conserved barrel domain protein
AS200_RS34705	COG1725	Transcriptional regulator
AS200_RS34740	COG0463	Glycosyl transferase, family 2
AS200_RS34750	COG2755	lipolytic protein G-D-S-L family
AS200_RS34755	COG2815	serine threonine protein kinase
AS200_RS34755	COG0515	serine threonine protein kinase
AS200_RS34775	COG1595	DNA-templated transcription, initiation
AS200_RS34810	COG2188	Transcriptional regulator
AS200_RS34815	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AS200_RS34825	COG1309	transcriptional regulator
AS200_RS34830	COG0243	molybdopterin cofactor binding
AS200_RS34835	COG2851	Citrate transporter
AS200_RS34855	COG3842	ATPase activity
AS200_RS34875	COG0640	Transcriptional regulator
AS200_RS34885	COG1960	acyl-CoA dehydrogenase activity
AS200_RS34905	COG0789	Transcriptional regulator
AS200_RS34935	COG3876	Protein conserved in bacteria
AS200_RS34945	COG0318	PFAM AMP-dependent synthetase and ligase
AS200_RS34980	COG2149	membrane
AS200_RS34985	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AS200_RS35020	COG1063	alcohol dehydrogenase
AS200_RS35025	COG1028	Short-chain dehydrogenase reductase Sdr
AS200_RS35035	COG3265	gluconokinase activity
AS200_RS35040	COG2186	Transcriptional regulator
AS200_RS35045	COG3012	SEC-C Motif Domain Protein
AS200_RS35050	COG0308	aminopeptidase N
AS200_RS35075	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AS200_RS35105	COG0667	Aldo Keto reductase
AS200_RS35110	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS200_RS35120	COG0598	Magnesium transport protein CorA
AS200_RS35125	COG0588	phosphoglycerate mutase activity
AS200_RS35140	COG0215	cysteine-tRNA ligase activity
AS200_RS35160	COG2186	Transcriptional regulator
AS200_RS35165	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AS200_RS35170	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AS200_RS35175	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AS200_RS35180	COG1414	Transcriptional regulator
AS200_RS35185	COG1410	methionine synthase
AS200_RS35185	COG0646	methionine synthase
AS200_RS35190	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AS200_RS35195	COG4166	transmembrane transport
AS200_RS35200	COG0747	negative chemotaxis
AS200_RS35205	COG2197	response regulator
AS200_RS35215	COG1994	Peptidase M50
AS200_RS35215	COG0517	IMP dehydrogenase activity
AS200_RS35235	COG1222	aaa ATPase
AS200_RS35240	COG4122	O-methyltransferase activity
AS200_RS35250	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
AS200_RS35255	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
AS200_RS35260	COG1609	Transcriptional regulator
AS200_RS35270	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
AS200_RS35275	COG0545	Peptidyl-prolyl cis-trans isomerase
AS200_RS35285	COG2378	regulation of single-species biofilm formation
AS200_RS35305	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AS200_RS35310	COG0805	protein transport
AS200_RS35380	COG3665	Urea carboxylase-associated protein
AS200_RS35435	COG2124	cytochrome p450
AS200_RS35470	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AS200_RS35480	COG4175	Glycine betaine
AS200_RS35480	COG0517	IMP dehydrogenase activity
AS200_RS35485	COG4176	ABC-type proline glycine betaine transport system permease component
AS200_RS35510	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AS200_RS35520	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AS200_RS35530	COG0174	glutamine synthetase
AS200_RS35535	COG1012	belongs to the aldehyde dehydrogenase family
AS200_RS35575	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AS200_RS35580	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AS200_RS35585	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AS200_RS35590	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AS200_RS35595	COG5002	protein histidine kinase activity
AS200_RS35600	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AS200_RS35605	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AS200_RS35605	COG0072	phenylalanine-tRNA ligase activity
AS200_RS35620	COG0494	nUDIX hydrolase
AS200_RS35635	COG1649	PFAM Uncharacterised BCR, COG1649
AS200_RS35645	COG0697	spore germination
AS200_RS35675	COG0789	Transcriptional regulator
AS200_RS35685	COG0463	Glycosyl transferase, family 2
AS200_RS35695	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AS200_RS35700	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AS200_RS35705	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AS200_RS35710	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AS200_RS35715	COG1438	arginine binding
AS200_RS35740	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AS200_RS35740	COG1017	nitric oxide dioxygenase activity
AS200_RS35745	COG0745	RESPONSE REGULATOR receiver
AS200_RS35750	COG2205	protein histidine kinase activity
AS200_RS35765	COG0165	Argininosuccinate lyase
AS200_RS35780	COG0477	Major facilitator Superfamily
AS200_RS35785	COG0318	PFAM AMP-dependent synthetase and ligase
AS200_RS35785	COG0204	Acyl-transferase
AS200_RS35790	COG0584	glycerophosphoryl diester phosphodiesterase
AS200_RS35815	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AS200_RS35820	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AS200_RS35825	COG2011	ABC-type metal ion transport system permease component
AS200_RS35830	COG1464	Belongs to the NlpA lipoprotein family
AS200_RS35845	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AS200_RS35850	COG1648	precorrin-2 dehydrogenase activity
AS200_RS35850	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AS200_RS35860	COG0494	nUDIX hydrolase
AS200_RS35915	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AS200_RS35965	COG1175	transmembrane transport
AS200_RS35970	COG0395	ABC-type sugar transport system, permease component
AS200_RS36000	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AS200_RS36015	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AS200_RS36020	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AS200_RS36040	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AS200_RS36045	COG1560	Kdo2-lipid A biosynthetic process
AS200_RS36050	COG0438	transferase activity, transferring glycosyl groups
AS200_RS36060	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
AS200_RS36065	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
AS200_RS36070	COG0217	transcriptional regulatory protein
AS200_RS36075	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AS200_RS36080	COG0632	four-way junction helicase activity
AS200_RS36085	COG2255	four-way junction helicase activity
AS200_RS36095	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AS200_RS36100	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AS200_RS36105	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AS200_RS36110	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AS200_RS36115	COG1196	nuclear chromosome segregation
AS200_RS36120	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AS200_RS36130	COG0124	histidyl-tRNA synthetase
AS200_RS36135	COG2197	response regulator
AS200_RS36140	COG4585	Histidine kinase
AS200_RS36150	COG1131	(ABC) transporter
AS200_RS36165	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AS200_RS36185	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AS200_RS36190	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AS200_RS36200	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AS200_RS36205	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AS200_RS36210	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AS200_RS36215	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AS200_RS36225	COG0006	proline dipeptidase activity
AS200_RS36230	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AS200_RS36235	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AS200_RS36245	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AS200_RS36250	COG0540	Belongs to the ATCase OTCase family
AS200_RS36255	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AS200_RS36265	COG0505	Belongs to the CarA family
AS200_RS36270	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AS200_RS36275	COG0167	dihydroorotate dehydrogenase activity
AS200_RS36280	COG0284	orotidine-5'-phosphate decarboxylase activity
AS200_RS36290	COG0194	GDP metabolic process
AS200_RS36295	COG1758	RNA polymerase activity
AS200_RS36305	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AS200_RS36320	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AS200_RS36330	COG2409	Drug exporters of the RND superfamily
AS200_RS36335	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AS200_RS36340	COG2390	Transcriptional regulator
AS200_RS36360	COG0531	amino acid
AS200_RS36380	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AS200_RS36405	COG2233	PERMEase
AS200_RS36420	COG2223	nitrite transmembrane transporter activity
AS200_RS36425	COG1846	Transcriptional regulator
AS200_RS36425	COG1940	carbohydrate kinase activity
AS200_RS36445	COG3201	nicotinamide mononucleotide transporter
AS200_RS36450	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AS200_RS36450	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AS200_RS36455	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AS200_RS36460	COG0140	phosphoribosyl-ATP diphosphatase activity
AS200_RS36465	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AS200_RS36510	COG1960	acyl-CoA dehydrogenase activity
AS200_RS36540	COG1216	Glycosyl transferase, family 2
AS200_RS36555	COG2270	Major facilitator Superfamily
AS200_RS36565	COG2364	Membrane
AS200_RS36570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS200_RS36595	COG0438	transferase activity, transferring glycosyl groups
AS200_RS36600	COG0438	transferase activity, transferring glycosyl groups
AS200_RS36610	COG1984	allophanate hydrolase subunit 2
AS200_RS36615	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AS200_RS36620	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AS200_RS36625	COG4336	lyase activity
AS200_RS36630	COG2814	Major facilitator Superfamily
AS200_RS36665	COG2018	Roadblock/LC7 domain
AS200_RS36685	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AS200_RS36695	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AS200_RS36705	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
AS200_RS36720	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AS200_RS36725	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS200_RS36740	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AS200_RS36770	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AS200_RS36790	COG1716	ATPase activity
AS200_RS36810	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AS200_RS36820	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AS200_RS36820	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AS200_RS36885	COG0395	ABC-type sugar transport system, permease component
AS200_RS36895	COG1609	Transcriptional regulator
AS200_RS36930	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AS200_RS36945	COG1695	Transcriptional regulator
AS200_RS36985	COG0697	spore germination
AS200_RS37030	COG0747	negative chemotaxis
AS200_RS37035	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AS200_RS37050	COG2318	DinB family
AS200_RS37070	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AS200_RS37080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS200_RS37085	COG1028	Short-chain dehydrogenase reductase Sdr
AS200_RS37095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS200_RS37105	COG1968	undecaprenyl-diphosphatase activity
AS200_RS37130	COG0183	Belongs to the thiolase family
AS200_RS37150	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AS200_RS37170	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AS200_RS37210	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AS200_RS37215	COG2326	polyphosphate kinase activity
AS200_RS37235	COG0110	maltose O-acetyltransferase activity
AS200_RS37260	COG1832	CoA-binding protein
AS200_RS37270	COG0215	cysteine-tRNA ligase activity
AS200_RS37280	COG1739	Uncharacterized protein family UPF0029
AS200_RS37285	COG0420	3'-5' exonuclease activity
AS200_RS37290	COG0419	ATPase involved in DNA repair
AS200_RS37295	COG1522	sequence-specific DNA binding
AS200_RS37320	COG0626	cystathionine gamma-synthase activity
AS200_RS37345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS200_RS37355	COG0596	Alpha beta hydrolase
AS200_RS37365	COG1595	DNA-templated transcription, initiation
AS200_RS37370	COG2188	Transcriptional regulator
AS200_RS37375	COG1940	carbohydrate kinase activity
AS200_RS37385	COG4585	Histidine kinase
AS200_RS37405	COG3663	DNA glycosylase
AS200_RS37410	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AS200_RS37435	COG0456	acetyltransferase
AS200_RS37440	COG0577	efflux transmembrane transporter activity
AS200_RS37440	COG1136	(ABC) transporter
AS200_RS37445	COG0577	efflux transmembrane transporter activity
AS200_RS37445	COG1136	(ABC) transporter
AS200_RS37460	COG2226	methyltransferase
AS200_RS37475	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AS200_RS37480	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AS200_RS37485	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AS200_RS37520	COG0740	serine-type endopeptidase activity
AS200_RS37530	COG0831	urea catabolic process
AS200_RS37535	COG0832	Belongs to the urease beta subunit family
AS200_RS37540	COG0804	urea catabolic process
AS200_RS37550	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AS200_RS37555	COG0829	nickel cation binding
AS200_RS37570	COG2226	methyltransferase
AS200_RS37585	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AS200_RS37590	COG1834	amidinotransferase
AS200_RS37595	COG1522	sequence-specific DNA binding
AS200_RS37600	COG3279	Response regulator of the LytR AlgR family
AS200_RS37610	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AS200_RS37615	COG3275	phosphorelay sensor kinase activity
AS200_RS37620	COG0515	serine threonine protein kinase
AS200_RS37620	COG2815	serine threonine protein kinase
AS200_RS37635	COG0483	inositol monophosphate 1-phosphatase activity
AS200_RS37640	COG0205	6-phosphofructokinase activity
AS200_RS37645	COG3442	glutamine amidotransferase
AS200_RS37655	COG0242	peptide deformylase activity
AS200_RS37665	COG1960	acyl-CoA dehydrogenase activity
AS200_RS37670	COG2197	response regulator
AS200_RS37680	COG1136	(ABC) transporter
AS200_RS37710	COG1793	dna ligase
AS200_RS37715	COG0492	ferredoxin-NADP+ reductase activity
AS200_RS37740	COG1960	acyl-CoA dehydrogenase activity
AS200_RS37745	COG1960	acyl-CoA dehydrogenase activity
AS200_RS37770	COG0456	acetyltransferase
AS200_RS37785	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AS200_RS37805	COG1309	transcriptional regulator
AS200_RS37810	COG1012	belongs to the aldehyde dehydrogenase family
AS200_RS37830	COG0531	amino acid
AS200_RS37835	COG1940	carbohydrate kinase activity
AS200_RS37835	COG1846	Transcriptional regulator
AS200_RS37860	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AS200_RS37865	COG3239	Fatty acid desaturase
AS200_RS37920	COG3845	ABC transporter
AS200_RS37930	COG2018	Roadblock/LC7 domain
AS200_RS37940	COG1946	Acyl-CoA thioesterase
AS200_RS37955	COG0254	rRNA binding
AS200_RS37965	COG1132	(ABC) transporter
AS200_RS37990	COG1132	(ABC) transporter
AS200_RS38005	COG0432	Pfam Uncharacterised protein family UPF0047
AS200_RS38010	COG2124	cytochrome p450
AS200_RS38045	COG0823	Involved in the tonB-independent uptake of proteins
AS200_RS38055	COG0714	Associated with various cellular activities
AS200_RS38080	COG3973	AAA domain
AS200_RS38085	COG5006	permease, DMT superfamily
AS200_RS38095	COG0596	Alpha beta hydrolase
AS200_RS38110	COG3903	Transcriptional regulator
AS200_RS38110	COG3629	intracellular signal transduction
AS200_RS38115	COG3903	Transcriptional regulator
AS200_RS38115	COG3629	intracellular signal transduction
AS200_RS38145	COG1090	epimerase
AS200_RS38150	COG1595	DNA-templated transcription, initiation
AS200_RS38190	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AS200_RS38220	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AS200_RS38240	COG1960	acyl-CoA dehydrogenase activity
AS200_RS38260	COG3509	depolymerase
AS200_RS38270	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AS200_RS38275	COG1902	pentaerythritol trinitrate reductase activity
AS200_RS38280	COG0640	Transcriptional regulator
AS200_RS38285	COG2233	PERMEase
AS200_RS38300	COG1309	transcriptional regulator
AS200_RS38310	COG0546	phosphoglycolate phosphatase activity
AS200_RS38330	COG1846	Transcriptional regulator
AS200_RS38350	COG0584	glycerophosphoryl diester phosphodiesterase
AS200_RS38385	COG0204	Acyl-transferase
AS200_RS38410	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AS200_RS38425	COG0515	serine threonine protein kinase
AS200_RS38425	COG2815	serine threonine protein kinase
AS200_RS38445	COG3345	alpha-galactosidase
AS200_RS38455	COG1660	Displays ATPase and GTPase activities
AS200_RS38465	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS200_RS38475	COG0445	tRNA wobble uridine modification
AS200_RS38490	COG4585	Histidine kinase
AS200_RS38495	COG2197	response regulator
AS200_RS38575	COG4585	Histidine kinase
AS200_RS38590	COG4552	Acetyltransferase involved in intracellular survival and related
AS200_RS38595	COG2197	response regulator
AS200_RS38600	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AS200_RS38605	COG1584	GPR1 FUN34 yaaH family protein
AS200_RS38620	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AS200_RS38620	COG0723	plastoquinol--plastocyanin reductase activity
AS200_RS38640	COG1609	Transcriptional regulator
AS200_RS38685	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AS200_RS38705	COG0640	Transcriptional regulator
AS200_RS38720	COG4585	Histidine kinase
AS200_RS38725	COG2197	response regulator
AS200_RS38730	COG0281	malic enzyme
AS200_RS38745	COG0789	Transcriptional regulator
AS200_RS38770	COG2226	methyltransferase
AS200_RS38780	COG2197	response regulator
AS200_RS38790	COG2409	Drug exporters of the RND superfamily
AS200_RS38800	COG0395	ABC-type sugar transport system, permease component
AS200_RS38805	COG1175	transmembrane transport
AS200_RS38820	COG1940	carbohydrate kinase activity
AS200_RS38825	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AS200_RS38840	COG1012	belongs to the aldehyde dehydrogenase family
AS200_RS38845	COG0517	IMP dehydrogenase activity
AS200_RS38845	COG4175	Glycine betaine
AS200_RS38865	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AS200_RS38870	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AS200_RS38895	COG0789	Transcriptional regulator
AS200_RS38940	COG1609	Transcriptional regulator
AS200_RS38950	COG2197	response regulator
AS200_RS38960	COG4716	Myosin-crossreactive antigen
AS200_RS39015	COG1252	NADH dehydrogenase
AS200_RS39020	COG2920	part of a sulfur-relay system
AS200_RS39035	COG1960	acyl-CoA dehydrogenase activity
AS200_RS39040	COG0028	Belongs to the TPP enzyme family
AS200_RS39050	COG0659	secondary active sulfate transmembrane transporter activity
AS200_RS39070	COG1316	TRANSCRIPTIONal
AS200_RS39080	COG0640	Transcriptional regulator
AS200_RS39085	COG0584	glycerophosphoryl diester phosphodiesterase
AS200_RS39115	COG3387	PFAM Glycoside hydrolase 15-related
AS200_RS39120	COG1349	DNA-binding transcription factor activity
AS200_RS39125	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AS200_RS39135	COG2813	Specifically methylates the guanine in position
AS200_RS39150	COG1940	carbohydrate kinase activity
AS200_RS39185	COG1136	(ABC) transporter
AS200_RS39190	COG0577	efflux transmembrane transporter activity
AS200_RS39215	COG1349	DNA-binding transcription factor activity
AS200_RS39250	COG1215	transferase activity, transferring glycosyl groups
AS200_RS39255	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AS200_RS39275	COG0494	nUDIX hydrolase
AS200_RS39280	COG1028	Short-chain dehydrogenase reductase Sdr
AS200_RS39310	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS200_RS39310	COG3321	synthase
AS200_RS39315	COG0318	PFAM AMP-dependent synthetase and ligase
AS200_RS39320	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AS200_RS39325	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AS200_RS39335	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AS200_RS39355	COG3340	Belongs to the peptidase S51 family
AS200_RS39370	COG1028	Short-chain dehydrogenase reductase Sdr
AS200_RS39395	COG0395	ABC-type sugar transport system, permease component
AS200_RS39400	COG1175	transmembrane transport
AS200_RS39435	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AS200_RS39440	COG1993	acr, cog1993
AS200_RS39445	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AS200_RS39450	COG1968	undecaprenyl-diphosphatase activity
AS200_RS39455	COG2186	Transcriptional regulator
AS200_RS39460	COG1113	amino acid transport
AS200_RS39475	COG2066	Belongs to the glutaminase family
AS200_RS39485	COG5650	phosphatidylinositol metabolic process
AS200_RS39505	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AS200_RS39510	COG3795	YCII-related domain
AS200_RS39520	COG4941	Belongs to the sigma-70 factor family
AS200_RS39545	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AS200_RS39570	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AS200_RS39590	COG2890	protein-(glutamine-N5) methyltransferase activity
AS200_RS39615	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AS200_RS39620	COG0446	pyridine nucleotide-disulphide oxidoreductase
AS200_RS39620	COG1902	pentaerythritol trinitrate reductase activity
AS200_RS39635	COG4733	cellulase activity
AS200_RS39635	COG5297	Belongs to the glycosyl hydrolase family 6
AS200_RS39645	COG1028	Short-chain dehydrogenase reductase Sdr
AS200_RS39650	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
AS200_RS39655	COG1461	Dihydroxyacetone kinase
AS200_RS39660	COG2376	Dihydroxyacetone kinase
AS200_RS39695	COG0531	amino acid
AS200_RS39700	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AS200_RS39705	COG0549	Belongs to the carbamate kinase family
AS200_RS39715	COG1366	Belongs to the anti-sigma-factor antagonist family
AS200_RS39720	COG1063	alcohol dehydrogenase
AS200_RS39770	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AS200_RS39780	COG2205	protein histidine kinase activity
AS200_RS39815	COG1012	belongs to the aldehyde dehydrogenase family
AS200_RS39835	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AS200_RS39845	COG0493	'glutamate synthase
AS200_RS39850	COG1013	pyruvate-flavodoxin oxidoreductase activity
AS200_RS39855	COG0674	pyruvate-flavodoxin oxidoreductase activity
AS200_RS39880	COG0517	IMP dehydrogenase activity
AS200_RS39880	COG0516	GMP reductase activity
AS200_RS39895	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AS200_RS39900	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AS200_RS39905	COG0508	dehydrogenase complex catalyzes the overall conversion of
AS200_RS39905	COG0022	dehydrogenase e1 component
AS200_RS39910	COG0508	dehydrogenase complex catalyzes the overall conversion of
AS200_RS39915	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AS200_RS39930	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AS200_RS39940	COG0589	response to stress
AS200_RS40010	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
AS200_RS40025	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AS200_RS40030	COG0569	domain protein
AS200_RS40045	COG3842	ATPase activity
AS200_RS40075	COG0517	IMP dehydrogenase activity
AS200_RS40075	COG0516	GMP reductase activity
AS200_RS40105	COG2326	polyphosphate kinase activity
AS200_RS40110	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AS200_RS40120	COG0517	IMP dehydrogenase activity
AS200_RS40120	COG0516	GMP reductase activity
AS200_RS40150	COG0309	Hydrogenase expression formation protein (HypE)
AS200_RS40160	COG0516	GMP reductase activity
AS200_RS40160	COG0517	IMP dehydrogenase activity
AS200_RS40195	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AS200_RS40215	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AS200_RS40215	COG0574	Belongs to the PEP-utilizing enzyme family
AS200_RS40220	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AS200_RS40230	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AS200_RS40250	COG1960	acyl-CoA dehydrogenase activity
AS200_RS40275	COG0667	Aldo Keto reductase
AS200_RS40290	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AS200_RS40295	COG2070	2-Nitropropane dioxygenase
AS200_RS40310	COG2366	antibiotic biosynthetic process
AS200_RS40315	COG0318	PFAM AMP-dependent synthetase and ligase
AS200_RS40330	COG0596	Alpha beta hydrolase
AS200_RS40350	COG1024	Enoyl-CoA hydratase
AS200_RS40475	COG3250	beta-galactosidase activity
AS200_RS40480	COG1940	carbohydrate kinase activity
AS200_RS40485	COG0531	amino acid
AS200_RS40505	COG1595	DNA-templated transcription, initiation
AS200_RS40520	COG3046	protein related to deoxyribodipyrimidine photolyase
AS200_RS40530	COG0702	epimerase
AS200_RS40535	COG1846	Transcriptional regulator
AS200_RS40540	COG2409	Drug exporters of the RND superfamily
AS200_RS40545	COG1191	sigma factor activity
AS200_RS40565	COG4941	Belongs to the sigma-70 factor family
AS200_RS40570	COG1012	belongs to the aldehyde dehydrogenase family
AS200_RS40610	COG0346	lactoylglutathione lyase activity
AS200_RS40615	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AS200_RS40625	COG0583	DNA-binding transcription factor activity
AS200_RS40640	COG0477	Major facilitator Superfamily
AS200_RS40645	COG0667	Aldo Keto reductase
AS200_RS40670	COG1131	(ABC) transporter
AS200_RS40670	COG0842	Transport permease protein
AS200_RS40670	COG1716	ATPase activity
AS200_RS40705	COG1191	sigma factor activity
AS200_RS40710	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AS200_RS40715	COG1396	sequence-specific DNA binding
AS200_RS40720	COG0740	serine-type endopeptidase activity
AS200_RS40725	COG0740	serine-type endopeptidase activity
AS200_RS40730	COG0596	Alpha beta hydrolase
AS200_RS40740	COG4122	O-methyltransferase activity
AS200_RS40760	COG0328	RNA-DNA hybrid ribonuclease activity
AS200_RS40805	COG0667	Aldo Keto reductase
AS200_RS40820	COG3647	Membrane
AS200_RS40830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS200_RS40840	COG0515	serine threonine protein kinase
AS200_RS40840	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AS200_RS40845	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AS200_RS40850	COG0142	geranyltranstransferase activity
AS200_RS40880	COG1940	carbohydrate kinase activity
AS200_RS40880	COG1846	Transcriptional regulator
AS200_RS40885	COG3345	alpha-galactosidase
AS200_RS40910	COG3852	Histidine kinase
AS200_RS40935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS200_RS40990	COG5002	protein histidine kinase activity
AS200_RS41030	COG1982	Orn Lys Arg decarboxylase major
AS200_RS41090	COG1366	Belongs to the anti-sigma-factor antagonist family
AS200_RS41095	COG1366	Belongs to the anti-sigma-factor antagonist family
AS200_RS41155	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AS200_RS41160	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AS200_RS41165	COG3281	Trehalose synthase
AS200_RS41175	COG0366	Alpha amylase catalytic
AS200_RS41210	COG1846	Transcriptional regulator
AS200_RS41220	COG0842	Transport permease protein
AS200_RS41230	COG0181	hydroxymethylbilane synthase activity
AS200_RS41240	COG1028	Short-chain dehydrogenase reductase Sdr
AS200_RS41250	COG0477	Major facilitator Superfamily
AS200_RS41310	COG1830	Aldolase
AS200_RS41315	COG0205	6-phosphofructokinase activity
AS200_RS41320	COG4044	May play a role in the intracellular transport of hydrophobic ligands
AS200_RS41325	COG2814	Major facilitator Superfamily
AS200_RS41345	COG0009	L-threonylcarbamoyladenylate synthase
AS200_RS41395	COG1473	amidohydrolase
AS200_RS41420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AS200_RS41495	COG0367	asparagine synthase
AS200_RS41505	COG1295	ribonuclease BN
AS200_RS41525	COG0038	chloride channel
AS200_RS41635	COG1028	Short-chain dehydrogenase reductase Sdr
AS200_RS41650	COG0628	permease
AS200_RS41685	COG0142	geranyltranstransferase activity
AS200_RS41705	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
AS200_RS41750	COG0583	DNA-binding transcription factor activity
AS200_RS41760	COG1191	sigma factor activity
AS200_RS41775	COG3537	Alpha-1,2-mannosidase
AS200_RS41790	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AS200_RS41810	COG0300	oxidoreductase activity
AS200_RS41830	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AS200_RS41845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AS200_RS41850	COG1609	Transcriptional regulator
AS200_RS41880	COG0318	PFAM AMP-dependent synthetase and ligase
AS200_RS41915	COG0515	serine threonine protein kinase
AS200_RS41915	COG2815	serine threonine protein kinase
AS200_RS41925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS200_RS41930	COG4172	Belongs to the ABC transporter superfamily
AS200_RS41935	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AS200_RS41965	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AS200_RS41970	COG1116	anion transmembrane transporter activity
AS200_RS41980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS200_RS41990	COG0765	amino acid transport
AS200_RS41995	COG1126	abc transporter atp-binding protein
AS200_RS42010	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS200_RS42015	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS200_RS42020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS200_RS42025	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS200_RS42030	COG0431	NADPH-dependent FMN reductase
AS200_RS42035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS200_RS42055	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AS200_RS42065	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AS200_RS42080	COG2188	Transcriptional regulator
AS200_RS42135	COG2124	cytochrome p450
AS200_RS42150	COG2226	methyltransferase
AS200_RS42160	COG1366	Belongs to the anti-sigma-factor antagonist family
AS200_RS42185	COG1349	DNA-binding transcription factor activity
AS200_RS42200	COG0395	ABC-type sugar transport system, permease component
AS200_RS42205	COG1063	alcohol dehydrogenase
AS200_RS42215	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AS200_RS42220	COG0640	Transcriptional regulator
AS200_RS42225	COG0798	PFAM Bile acid sodium symporter
AS200_RS42230	COG0640	Transcriptional regulator
AS200_RS42255	COG1819	glycosyl
AS200_RS42275	COG0667	Aldo Keto reductase
AS200_RS42280	COG1609	Transcriptional regulator
AS200_RS42280	COG2207	Transcriptional regulator
AS200_RS42295	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AS200_RS42305	COG1028	Short-chain dehydrogenase reductase Sdr
AS200_RS42330	COG0477	Major facilitator Superfamily
AS200_RS42355	COG2132	Multicopper oxidase
AS200_RS42365	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AS200_RS42370	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AS200_RS42375	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AS200_RS42380	COG3547	Transposase (IS116 IS110 IS902 family)
AS200_RS42385	COG0009	L-threonylcarbamoyladenylate synthase
AS200_RS42430	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AS200_RS42445	COG2197	response regulator
AS200_RS42475	COG1011	Hydrolase
AS200_RS42505	COG0513	Belongs to the DEAD box helicase family
AS200_RS42510	COG1278	Cold shock
AS200_RS42540	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AS200_RS42555	COG5002	protein histidine kinase activity
AS200_RS42560	COG0745	RESPONSE REGULATOR receiver
AS200_RS42565	COG2409	Drug exporters of the RND superfamily
AS200_RS42620	COG3226	Transcriptional regulator
AS200_RS42650	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AS200_RS42660	COG0640	Transcriptional regulator
AS200_RS42700	COG1028	Short-chain dehydrogenase reductase Sdr
AS200_RS42715	COG0346	lactoylglutathione lyase activity
AS200_RS42725	COG2814	Major facilitator Superfamily
AS200_RS42740	COG0583	DNA-binding transcription factor activity
AS200_RS42760	COG4948	Mandelate Racemase Muconate Lactonizing
AS200_RS42765	COG3265	gluconokinase activity
AS200_RS42785	COG0784	Response regulator, receiver
AS200_RS42795	COG4251	negative regulation of phosphorylation
AS200_RS42835	COG0456	acetyltransferase
AS200_RS42840	COG0583	DNA-binding transcription factor activity
AS200_RS42850	COG4213	ABC transporter substrate-binding protein
AS200_RS42855	COG4214	carbohydrate transport
AS200_RS42865	COG1940	carbohydrate kinase activity
AS200_RS42910	COG0662	Cupin 2, conserved barrel domain protein
AS200_RS42935	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AS200_RS42965	COG1136	(ABC) transporter
AS200_RS42980	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
AS200_RS43095	COG2188	Transcriptional regulator
AS200_RS43100	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AS200_RS43135	COG4733	cellulase activity
AS200_RS43135	COG5297	Belongs to the glycosyl hydrolase family 6
AS200_RS43160	COG3844	kynureninase activity
AS200_RS43170	COG3483	tryptophan 2,3-dioxygenase activity
AS200_RS43180	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AS200_RS43185	COG2151	metal-sulfur cluster biosynthetic enzyme
AS200_RS43190	COG3396	Phenylacetate-CoA oxygenase
AS200_RS43200	COG3396	Phenylacetate-CoA oxygenase
AS200_RS43210	COG0318	PFAM AMP-dependent synthetase and ligase
AS200_RS43220	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AS200_RS43225	COG1846	Transcriptional regulator
AS200_RS43230	COG0604	alcohol dehydrogenase
AS200_RS43240	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS200_RS43270	COG0300	oxidoreductase activity
AS200_RS43315	COG0395	ABC-type sugar transport system, permease component
AS200_RS43345	COG0596	Alpha beta hydrolase
AS200_RS43350	COG1846	Transcriptional regulator
AS200_RS43355	COG0697	spore germination
AS200_RS43360	COG1301	dicarboxylic acid transport
AS200_RS43365	COG2828	Protein conserved in bacteria
AS200_RS43440	COG4221	oxidoreductase activity
AS200_RS43450	COG1131	(ABC) transporter
AS200_RS43460	COG4585	Histidine kinase
AS200_RS43465	COG2197	response regulator
AS200_RS43470	COG1032	radical SAM domain protein
AS200_RS43485	COG2255	four-way junction helicase activity
AS200_RS43500	COG1408	metallophosphoesterase
AS200_RS43505	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AS200_RS43535	COG1028	Short-chain dehydrogenase reductase Sdr
AS200_RS43540	COG1309	transcriptional regulator
AS200_RS43550	COG0596	Alpha beta hydrolase
AS200_RS43560	COG0596	Alpha beta hydrolase
AS200_RS43595	COG0641	radical SAM
AS200_RS43655	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AS200_RS43665	COG3290	protein histidine kinase activity
AS200_RS43670	COG4565	transcriptional regulatory protein
AS200_RS43675	COG0583	DNA-binding transcription factor activity
AS200_RS43690	COG1191	sigma factor activity
AS200_RS43795	COG1012	belongs to the aldehyde dehydrogenase family
AS200_RS43805	COG0583	DNA-binding transcription factor activity
AS200_RS43815	COG0656	L-ascorbic acid biosynthetic process
AS200_RS43830	COG0693	protein deglycase activity
AS200_RS43835	COG0443	Heat shock 70 kDa protein
AS200_RS43840	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AS200_RS43845	COG0484	heat shock protein binding
AS200_RS43855	COG0542	response to heat
AS200_RS43875	COG0071	Belongs to the small heat shock protein (HSP20) family
AS200_RS43895	COG0702	epimerase
AS200_RS43910	COG3835	regulator
AS200_RS43925	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AS200_RS43930	COG2197	response regulator
AS200_RS43935	COG4585	Histidine kinase
AS200_RS43980	COG0667	Aldo Keto reductase
AS200_RS44050	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AS200_RS44080	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AS200_RS44100	COG4565	transcriptional regulatory protein
AS200_RS44105	COG3290	protein histidine kinase activity
AS200_RS44120	COG4585	Histidine kinase
AS200_RS44135	COG2272	Belongs to the type-B carboxylesterase lipase family
AS200_RS44185	COG2770	Histidine kinase
AS200_RS44185	COG2208	phosphoserine phosphatase activity
AS200_RS44200	COG0745	RESPONSE REGULATOR receiver
AS200_RS44205	COG2205	protein histidine kinase activity
AS200_RS44240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AS200_RS44245	COG0789	Transcriptional regulator
AS200_RS44270	COG0702	epimerase
AS200_RS44290	COG3328	transposase activity