locus-tag	class	description
SFR_RS00025	COG3293	Transposase
SFR_RS00045	COG3293	Transposase
SFR_RS00070	COG2801	Transposase and inactivated derivatives
SFR_RS00085	COG2197	response regulator
SFR_RS00090	COG4585	Histidine kinase
SFR_RS00110	COG1136	(ABC) transporter
SFR_RS00110	COG4591	ABC-type transport system involved in lipoprotein release permease component
SFR_RS00135	COG2801	Transposase and inactivated derivatives
SFR_RS00145	COG2205	protein histidine kinase activity
SFR_RS00150	COG0745	RESPONSE REGULATOR receiver
SFR_RS00155	COG0577	efflux transmembrane transporter activity
SFR_RS00165	COG1136	(ABC) transporter
SFR_RS00200	COG3386	PFAM SMP-30 Gluconolaconase
SFR_RS00205	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SFR_RS00210	COG0800	Aldolase
SFR_RS00215	COG4948	Mandelate Racemase Muconate Lactonizing
SFR_RS00220	COG2186	Transcriptional regulator
SFR_RS00230	COG1063	alcohol dehydrogenase
SFR_RS00235	COG1172	Belongs to the binding-protein-dependent transport system permease family
SFR_RS00240	COG1129	ABC transporter
SFR_RS00245	COG1879	ABC-type sugar transport system periplasmic component
SFR_RS00275	COG1028	Short-chain dehydrogenase reductase Sdr
SFR_RS00310	COG1472	Belongs to the glycosyl hydrolase 3 family
SFR_RS00315	COG1874	Beta-galactosidase
SFR_RS00320	COG1609	Transcriptional regulator
SFR_RS00325	COG0395	ABC-type sugar transport system, permease component
SFR_RS00330	COG1175	transmembrane transport
SFR_RS00350	COG1028	Short-chain dehydrogenase reductase Sdr
SFR_RS00355	COG0477	Major facilitator Superfamily
SFR_RS00380	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SFR_RS00385	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
SFR_RS00390	COG2080	2 iron, 2 sulfur cluster binding
SFR_RS00400	COG2197	response regulator
SFR_RS00405	COG4585	Histidine kinase
SFR_RS00410	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
SFR_RS00485	COG0446	pyridine nucleotide-disulphide oxidoreductase
SFR_RS00485	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SFR_RS00535	COG4608	Belongs to the ABC transporter superfamily
SFR_RS00540	COG0444	Belongs to the ABC transporter superfamily
SFR_RS00545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SFR_RS00550	COG0601	transmembrane transport
SFR_RS00555	COG0747	negative chemotaxis
SFR_RS00565	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SFR_RS00590	COG1793	dna ligase
SFR_RS00625	COG0277	FAD linked oxidase domain protein
SFR_RS00685	COG0318	PFAM AMP-dependent synthetase and ligase
SFR_RS00690	COG0589	response to stress
SFR_RS00695	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SFR_RS00700	COG2813	Specifically methylates the guanine in position
SFR_RS00710	COG2356	endonuclease I
SFR_RS00740	COG2084	Dehydrogenase
SFR_RS00755	COG2267	carboxylic ester hydrolase activity
SFR_RS00780	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SFR_RS00785	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SFR_RS00790	COG0713	ATP synthesis coupled electron transport
SFR_RS00800	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SFR_RS00810	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SFR_RS00830	COG0446	pyridine nucleotide-disulphide oxidoreductase
SFR_RS00830	COG1902	pentaerythritol trinitrate reductase activity
SFR_RS00840	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SFR_RS00875	COG0475	glutathione-regulated potassium exporter activity
SFR_RS00895	COG2197	response regulator
SFR_RS00910	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SFR_RS00925	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SFR_RS00935	COG3268	Saccharopine dehydrogenase
SFR_RS00970	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
SFR_RS00975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SFR_RS00985	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SFR_RS00990	COG1535	isochorismatase
SFR_RS00990	COG3433	isochorismatase activity
SFR_RS01010	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SFR_RS01015	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SFR_RS01070	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SFR_RS01075	COG1181	Belongs to the D-alanine--D-alanine ligase family
SFR_RS01085	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SFR_RS01105	COG3559	Exporter of polyketide antibiotics
SFR_RS01110	COG1131	(ABC) transporter
SFR_RS01115	COG1309	transcriptional regulator
SFR_RS01120	COG0477	Major facilitator Superfamily
SFR_RS01135	COG0328	RNA-DNA hybrid ribonuclease activity
SFR_RS01140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SFR_RS01145	COG0431	NADPH-dependent FMN reductase
SFR_RS01175	COG1595	DNA-templated transcription, initiation
SFR_RS01200	COG0667	Aldo Keto reductase
SFR_RS01235	COG1562	ergosterol biosynthetic process
SFR_RS01240	COG1131	(ABC) transporter
SFR_RS01260	COG0326	Molecular chaperone. Has ATPase activity
SFR_RS01280	COG0702	epimerase
SFR_RS01290	COG0346	lactoylglutathione lyase activity
SFR_RS01295	COG0640	Transcriptional regulator
SFR_RS01310	COG1120	ATPase activity
SFR_RS01330	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SFR_RS01340	COG1960	acyl-CoA dehydrogenase activity
SFR_RS01350	COG1250	3-hydroxyacyl-CoA dehydrogenase
SFR_RS01360	COG3321	synthase
SFR_RS01360	COG1028	Short-chain dehydrogenase reductase Sdr
SFR_RS01360	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SFR_RS01360	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SFR_RS01360	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SFR_RS01365	COG3321	synthase
SFR_RS01365	COG1028	Short-chain dehydrogenase reductase Sdr
SFR_RS01365	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SFR_RS01365	COG4221	oxidoreductase activity
SFR_RS01380	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SFR_RS01395	COG1349	DNA-binding transcription factor activity
SFR_RS01405	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SFR_RS01405	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
SFR_RS01405	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SFR_RS01410	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
SFR_RS01410	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SFR_RS01415	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SFR_RS01440	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SFR_RS01470	COG1695	Transcriptional regulator
SFR_RS01495	COG1028	Short-chain dehydrogenase reductase Sdr
SFR_RS01510	COG0513	Belongs to the DEAD box helicase family
SFR_RS01520	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SFR_RS01535	COG3217	Mosc domain protein beta barrel domain protein
SFR_RS01535	COG0633	Ferredoxin
SFR_RS01555	COG1349	DNA-binding transcription factor activity
SFR_RS01575	COG1940	carbohydrate kinase activity
SFR_RS01585	COG2223	nitrite transmembrane transporter activity
SFR_RS01600	COG2197	response regulator
SFR_RS01615	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SFR_RS01640	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
SFR_RS01680	COG0584	glycerophosphoryl diester phosphodiesterase
SFR_RS01695	COG1846	Transcriptional regulator
SFR_RS01715	COG0671	phosphoesterase, PA-phosphatase related
SFR_RS01745	COG2233	PERMEase
SFR_RS01750	COG0640	Transcriptional regulator
SFR_RS01755	COG1902	pentaerythritol trinitrate reductase activity
SFR_RS01770	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SFR_RS01785	COG2706	6-phosphogluconolactonase activity
SFR_RS01795	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SFR_RS01800	COG0071	Belongs to the small heat shock protein (HSP20) family
SFR_RS01805	COG0076	glutamate decarboxylase activity
SFR_RS01810	COG0243	molybdopterin cofactor binding
SFR_RS01825	COG0303	'Molybdopterin
SFR_RS01830	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SFR_RS01845	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
SFR_RS01850	COG0583	DNA-binding transcription factor activity
SFR_RS01895	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SFR_RS01900	COG1120	ATPase activity
SFR_RS01905	COG2207	Transcriptional regulator
SFR_RS01910	COG2814	Major facilitator Superfamily
SFR_RS01935	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
SFR_RS01950	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
SFR_RS01970	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
SFR_RS01990	COG0477	Major facilitator Superfamily
SFR_RS01995	COG1309	transcriptional regulator
SFR_RS02005	COG1472	Belongs to the glycosyl hydrolase 3 family
SFR_RS02015	COG1175	transmembrane transport
SFR_RS02025	COG1609	Transcriptional regulator
SFR_RS02050	COG0432	Pfam Uncharacterised protein family UPF0047
SFR_RS02055	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SFR_RS02060	COG1116	anion transmembrane transporter activity
SFR_RS02070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SFR_RS02075	COG0492	ferredoxin-NADP+ reductase activity
SFR_RS02080	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SFR_RS02085	COG1132	(ABC) transporter
SFR_RS02105	COG1132	(ABC) transporter
SFR_RS02110	COG1132	(ABC) transporter
SFR_RS02125	COG1946	Acyl-CoA thioesterase
SFR_RS02140	COG2018	Roadblock/LC7 domain
SFR_RS02185	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SFR_RS02210	COG1070	Carbohydrate kinase
SFR_RS02220	COG2124	cytochrome p450
SFR_RS02225	COG2130	NADP-dependent
SFR_RS02305	COG0477	Major facilitator Superfamily
SFR_RS02310	COG0183	Belongs to the thiolase family
SFR_RS02315	COG0583	DNA-binding transcription factor activity
SFR_RS02320	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
SFR_RS02325	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
SFR_RS02330	COG1250	3-hydroxyacyl-CoA dehydrogenase
SFR_RS02335	COG1960	acyl-CoA dehydrogenase activity
SFR_RS02385	COG0740	serine-type endopeptidase activity
SFR_RS02390	COG0740	serine-type endopeptidase activity
SFR_RS02425	COG4521	taurine ABC transporter
SFR_RS02430	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SFR_RS02450	COG3959	Transketolase, thiamine diphosphate binding domain
SFR_RS02455	COG3958	Transketolase
SFR_RS02525	COG2755	lipolytic protein G-D-S-L family
SFR_RS02530	COG2365	Tyrosine phosphatase family
SFR_RS02560	COG1657	PFAM Prenyltransferase squalene oxidase
SFR_RS02570	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SFR_RS02580	COG1562	ergosterol biosynthetic process
SFR_RS02585	COG1134	teichoic acid transport
SFR_RS02585	COG1388	LysM domain
SFR_RS02610	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SFR_RS02625	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
SFR_RS02640	COG1024	Enoyl-CoA hydratase
SFR_RS02655	COG2183	response to ionizing radiation
SFR_RS02670	COG1802	Transcriptional regulator
SFR_RS02675	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SFR_RS02680	COG0402	S-adenosylhomocysteine deaminase activity
SFR_RS02705	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SFR_RS02710	COG0789	Transcriptional regulator
SFR_RS02715	COG1250	3-hydroxyacyl-CoA dehydrogenase
SFR_RS02715	COG1024	Enoyl-CoA hydratase
SFR_RS02720	COG0183	Belongs to the thiolase family
SFR_RS02730	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SFR_RS02735	COG1683	Conserved Protein
SFR_RS02740	COG1515	deoxyribonuclease V activity
SFR_RS02770	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SFR_RS02780	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SFR_RS02780	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SFR_RS02790	COG0488	(ABC) transporter
SFR_RS02810	COG0438	transferase activity, transferring glycosyl groups
SFR_RS02845	COG0254	rRNA binding
SFR_RS02855	COG1793	dna ligase
SFR_RS02860	COG1024	Enoyl-CoA hydratase
SFR_RS02895	COG0789	Transcriptional regulator
SFR_RS02940	COG1846	Transcriptional regulator
SFR_RS03000	COG1012	belongs to the aldehyde dehydrogenase family
SFR_RS03025	COG2259	Doxx family
SFR_RS03035	COG1869	D-ribose catabolic process
SFR_RS03040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SFR_RS03045	COG1172	Belongs to the binding-protein-dependent transport system permease family
SFR_RS03050	COG1129	ABC transporter
SFR_RS03055	COG1609	Transcriptional regulator
SFR_RS03075	COG1295	ribonuclease BN
SFR_RS03140	COG0673	inositol 2-dehydrogenase activity
SFR_RS03150	COG1172	Belongs to the binding-protein-dependent transport system permease family
SFR_RS03155	COG1129	ABC transporter
SFR_RS03160	COG1940	carbohydrate kinase activity
SFR_RS03165	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SFR_RS03175	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
SFR_RS03185	COG0583	DNA-binding transcription factor activity
SFR_RS03190	COG1115	amino acid carrier protein
SFR_RS03215	COG2154	pterin-4-alpha-carbinolamine dehydratase
SFR_RS03245	COG1140	nitrate reductase beta subunit
SFR_RS03305	COG0693	protein deglycase activity
SFR_RS03315	COG1597	lipid kinase activity
SFR_RS03320	COG4106	trans-aconitate 2-methyltransferase activity
SFR_RS03335	COG3226	Transcriptional regulator
SFR_RS03345	COG0604	alcohol dehydrogenase
SFR_RS03360	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SFR_RS03380	COG1619	proteins homologs of microcin C7 resistance protein MccF
SFR_RS03390	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SFR_RS03435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SFR_RS03440	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SFR_RS03445	COG1120	ATPase activity
SFR_RS03450	COG1250	3-hydroxyacyl-CoA dehydrogenase
SFR_RS03460	COG0604	alcohol dehydrogenase
SFR_RS03465	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SFR_RS03465	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SFR_RS03470	COG2301	Belongs to the HpcH HpaI aldolase family
SFR_RS03485	COG0688	phosphatidylethanolamine metabolic process
SFR_RS03495	COG1929	Belongs to the glycerate kinase type-1 family
SFR_RS03500	COG0488	(ABC) transporter
SFR_RS03515	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
SFR_RS03520	COG0702	epimerase
SFR_RS03525	COG1028	Short-chain dehydrogenase reductase Sdr
SFR_RS03535	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
SFR_RS03560	COG0159	tryptophan synthase activity
SFR_RS03575	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
SFR_RS03590	COG0483	inositol monophosphate 1-phosphatase activity
SFR_RS03600	COG0095	Lipoate-protein ligase
SFR_RS03620	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SFR_RS03645	COG0405	Gamma-glutamyltransferase
SFR_RS03675	COG0765	amino acid transport
SFR_RS03680	COG0765	amino acid transport
SFR_RS03685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SFR_RS03690	COG1126	abc transporter atp-binding protein
SFR_RS03720	COG1228	amidohydrolase
SFR_RS03725	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SFR_RS03740	COG1960	acyl-CoA dehydrogenase activity
SFR_RS03770	COG5183	chlorophyll binding
SFR_RS03770	COG2133	pyrroloquinoline quinone binding
SFR_RS03775	COG1132	(ABC) transporter
SFR_RS03780	COG1132	(ABC) transporter
SFR_RS03785	COG1120	ATPase activity
SFR_RS03790	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SFR_RS03795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SFR_RS03800	COG2375	cellular response to nickel ion
SFR_RS03805	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SFR_RS03810	COG2207	Transcriptional regulator
SFR_RS03840	COG2197	response regulator
SFR_RS03850	COG0464	growth
SFR_RS03930	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SFR_RS03940	COG1940	carbohydrate kinase activity
SFR_RS03950	COG1172	Belongs to the binding-protein-dependent transport system permease family
SFR_RS03960	COG2188	Transcriptional regulator
SFR_RS03965	COG0673	inositol 2-dehydrogenase activity
SFR_RS03980	COG2197	response regulator
SFR_RS03985	COG4585	Histidine kinase
SFR_RS04000	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SFR_RS04005	COG1414	Transcriptional regulator
SFR_RS04020	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SFR_RS04025	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
SFR_RS04030	COG2080	2 iron, 2 sulfur cluster binding
SFR_RS04035	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
SFR_RS04050	COG4941	Belongs to the sigma-70 factor family
SFR_RS04055	COG3795	YCII-related domain
SFR_RS04060	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SFR_RS04065	COG1621	beta-fructofuranosidase activity
SFR_RS04085	COG1609	Transcriptional regulator
SFR_RS04135	COG2233	PERMEase
SFR_RS04150	COG2351	hydroxyisourate hydrolase activity
SFR_RS04170	COG3622	Belongs to the hyi family
SFR_RS04175	COG2084	Dehydrogenase
SFR_RS04180	COG0753	catalase activity
SFR_RS04185	COG3960	tartronate-semialdehyde synthase activity
SFR_RS04200	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SFR_RS04205	COG2197	response regulator
SFR_RS04215	COG1309	transcriptional regulator
SFR_RS04255	COG2252	PERMEase
SFR_RS04260	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SFR_RS04275	COG3835	regulator
SFR_RS04280	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SFR_RS04290	COG1802	Transcriptional regulator
SFR_RS04305	COG1028	Short-chain dehydrogenase reductase Sdr
SFR_RS04320	COG0028	Belongs to the TPP enzyme family
SFR_RS04340	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SFR_RS04345	COG1162	GTPase activity
SFR_RS04355	COG2365	Tyrosine phosphatase family
SFR_RS04395	COG1595	DNA-templated transcription, initiation
SFR_RS04415	COG0702	epimerase
SFR_RS04420	COG1846	Transcriptional regulator
SFR_RS04425	COG2409	Drug exporters of the RND superfamily
SFR_RS04435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SFR_RS04440	COG1120	ATPase activity
SFR_RS04450	COG2255	four-way junction helicase activity
SFR_RS04475	COG2040	homocysteine
SFR_RS04495	COG1960	acyl-CoA dehydrogenase activity
SFR_RS04505	COG0604	alcohol dehydrogenase
SFR_RS04530	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SFR_RS04540	COG0175	sulfate reduction
SFR_RS04545	COG0529	Catalyzes the synthesis of activated sulfate
SFR_RS04570	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
SFR_RS04575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SFR_RS04590	COG0386	Belongs to the glutathione peroxidase family
SFR_RS04625	COG5002	protein histidine kinase activity
SFR_RS04625	COG2176	DNA-directed DNA polymerase activity
SFR_RS04695	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SFR_RS04700	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SFR_RS04720	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
SFR_RS04725	COG1595	DNA-templated transcription, initiation
SFR_RS04740	COG0726	polysaccharide deacetylase
SFR_RS04750	COG3220	belongs to the UPF0276 family
SFR_RS04760	COG3253	May function as heme-dependent peroxidase
SFR_RS04765	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SFR_RS04775	COG0446	pyridine nucleotide-disulphide oxidoreductase
SFR_RS04780	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
SFR_RS04800	COG0183	Belongs to the thiolase family
SFR_RS04805	COG1250	3-hydroxyacyl-CoA dehydrogenase
SFR_RS04805	COG1024	Enoyl-CoA hydratase
SFR_RS04825	COG0531	amino acid
SFR_RS04830	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SFR_RS04835	COG4214	carbohydrate transport
SFR_RS04845	COG4213	ABC transporter substrate-binding protein
SFR_RS04855	COG0395	ABC-type sugar transport system, permease component
SFR_RS04860	COG1175	transmembrane transport
SFR_RS04865	COG1653	transport
SFR_RS04880	COG2161	toxin-antitoxin pair type II binding
SFR_RS04930	COG2815	serine threonine protein kinase
SFR_RS04930	COG0515	serine threonine protein kinase
SFR_RS04935	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
SFR_RS04970	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SFR_RS04990	COG1120	ATPase activity
SFR_RS04995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SFR_RS05000	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SFR_RS05020	COG2235	arginine
SFR_RS05025	COG1320	monovalent cation:proton antiporter activity
SFR_RS05040	COG0651	ATP synthesis coupled electron transport
SFR_RS05045	COG1006	Multisubunit Na H antiporter MnhC subunit
SFR_RS05050	COG2111	Na H antiporter
SFR_RS05050	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SFR_RS05060	COG2124	cytochrome p450
SFR_RS05090	COG0531	amino acid
SFR_RS05095	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SFR_RS05100	COG2235	arginine
SFR_RS05140	COG1799	cell septum assembly
SFR_RS05150	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
SFR_RS05165	COG1556	Lactate utilization protein
SFR_RS05170	COG1139	Iron-sulfur cluster binding protein
SFR_RS05175	COG0247	lactate metabolic process
SFR_RS05180	COG1620	l-lactate permease
SFR_RS05190	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
SFR_RS05230	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SFR_RS05235	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SFR_RS05250	COG1120	ATPase activity
SFR_RS05255	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SFR_RS05260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SFR_RS05270	COG1733	regulation of RNA biosynthetic process
SFR_RS05285	COG4172	Belongs to the ABC transporter superfamily
SFR_RS05290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SFR_RS05295	COG0601	transmembrane transport
SFR_RS05305	COG0747	negative chemotaxis
SFR_RS05315	COG1309	transcriptional regulator
SFR_RS05330	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SFR_RS05345	COG2936	dipeptidyl-peptidase activity
SFR_RS05365	COG3540	Alkaline phosphatase
SFR_RS05375	COG2050	protein possibly involved in aromatic compounds catabolism
SFR_RS05390	COG0789	Transcriptional regulator
SFR_RS05395	COG0640	Transcriptional regulator
SFR_RS05415	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
SFR_RS05465	COG3226	Transcriptional regulator
SFR_RS05470	COG0738	Major facilitator superfamily
SFR_RS05485	COG4213	ABC transporter substrate-binding protein
SFR_RS05490	COG1172	Belongs to the binding-protein-dependent transport system permease family
SFR_RS05495	COG1172	Belongs to the binding-protein-dependent transport system permease family
SFR_RS05500	COG1129	ABC transporter
SFR_RS05505	COG1940	carbohydrate kinase activity
SFR_RS05505	COG1846	Transcriptional regulator
SFR_RS05510	COG0252	asparaginase activity
SFR_RS05520	COG1028	Short-chain dehydrogenase reductase Sdr
SFR_RS05540	COG1028	Short-chain dehydrogenase reductase Sdr
SFR_RS05555	COG1028	Short-chain dehydrogenase reductase Sdr
SFR_RS05590	COG0473	3-isopropylmalate dehydrogenase activity
SFR_RS05605	COG0656	L-ascorbic acid biosynthetic process
SFR_RS05640	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
SFR_RS05665	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
SFR_RS05675	COG1127	ABC transporter
SFR_RS05710	COG0583	DNA-binding transcription factor activity
SFR_RS05720	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SFR_RS05735	COG4221	oxidoreductase activity
SFR_RS05740	COG0300	oxidoreductase activity
SFR_RS05805	COG2233	PERMEase
SFR_RS05810	COG0402	S-adenosylhomocysteine deaminase activity
SFR_RS05825	COG0559	Belongs to the binding-protein-dependent transport system permease family
SFR_RS05860	COG0395	ABC-type sugar transport system, permease component
SFR_RS05865	COG1063	alcohol dehydrogenase
SFR_RS05880	COG0438	transferase activity, transferring glycosyl groups
SFR_RS05885	COG2197	response regulator
SFR_RS05895	COG0577	efflux transmembrane transporter activity
SFR_RS05895	COG1136	(ABC) transporter
SFR_RS05905	COG2197	response regulator
SFR_RS05915	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SFR_RS05925	COG3251	PFAM MbtH domain protein
SFR_RS05935	COG2175	clavaminate synthase activity
SFR_RS05965	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SFR_RS05970	COG0531	amino acid
SFR_RS05975	COG0569	domain protein
SFR_RS06005	COG1136	(ABC) transporter
SFR_RS06005	COG4591	ABC-type transport system involved in lipoprotein release permease component
SFR_RS06025	COG0756	dUTP diphosphatase activity
SFR_RS06050	COG2205	protein histidine kinase activity
SFR_RS06055	COG0745	RESPONSE REGULATOR receiver
SFR_RS06060	COG0483	inositol monophosphate 1-phosphatase activity
SFR_RS06065	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SFR_RS06115	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SFR_RS06120	COG1802	Transcriptional regulator
SFR_RS06135	COG0612	Peptidase, M16
SFR_RS06140	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SFR_RS06150	COG0366	Alpha amylase catalytic
SFR_RS06155	COG0395	ABC-type sugar transport system, permease component
SFR_RS06160	COG1175	transmembrane transport
SFR_RS06165	COG1653	transport
SFR_RS06180	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SFR_RS06200	COG0187	DNA topoisomerase II activity
SFR_RS06215	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SFR_RS06220	COG1802	Transcriptional regulator
SFR_RS06255	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SFR_RS06270	COG0588	phosphoglycerate mutase activity
SFR_RS06290	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SFR_RS06295	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SFR_RS06300	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SFR_RS06340	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SFR_RS06350	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SFR_RS06355	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SFR_RS06365	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SFR_RS06385	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SFR_RS06395	COG2205	protein histidine kinase activity
SFR_RS06400	COG0745	RESPONSE REGULATOR receiver
SFR_RS06405	COG1126	abc transporter atp-binding protein
SFR_RS06410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SFR_RS06415	COG0765	amino acid transport
SFR_RS06420	COG0765	amino acid transport
SFR_RS06425	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SFR_RS06445	COG2137	regulation of response to DNA damage stimulus
SFR_RS06450	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SFR_RS06475	COG0628	permease
SFR_RS06500	COG1201	RNA secondary structure unwinding
SFR_RS06505	COG0596	Alpha beta hydrolase
SFR_RS06525	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SFR_RS06535	COG0783	Belongs to the Dps family
SFR_RS06540	COG1396	sequence-specific DNA binding
SFR_RS06545	COG1546	Belongs to the CinA family
SFR_RS06545	COG1058	Belongs to the CinA family
SFR_RS06555	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SFR_RS06565	COG1674	ftsk spoiiie
SFR_RS06575	COG2205	protein histidine kinase activity
SFR_RS06575	COG3437	response regulator, receiver
SFR_RS06575	COG3850	Histidine kinase
SFR_RS06575	COG4999	Histidine kinase
SFR_RS06625	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SFR_RS06630	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
SFR_RS06650	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SFR_RS06655	COG0612	Peptidase, M16
SFR_RS06660	COG1185	polyribonucleotide nucleotidyltransferase activity
SFR_RS06665	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
SFR_RS06680	COG0747	negative chemotaxis
SFR_RS06685	COG0601	transmembrane transport
SFR_RS06690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SFR_RS06695	COG0444	Belongs to the ABC transporter superfamily
SFR_RS06700	COG4608	Belongs to the ABC transporter superfamily
SFR_RS06705	COG1357	PFAM Pentapeptide repeats (8 copies)
SFR_RS06730	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SFR_RS06735	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SFR_RS06745	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SFR_RS06760	COG0779	Required for maturation of 30S ribosomal subunits
SFR_RS06780	COG0442	prolyl-tRNA aminoacylation
SFR_RS06800	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SFR_RS06805	COG0601	transmembrane transport
SFR_RS06810	COG0747	negative chemotaxis
SFR_RS06830	COG0750	zinc metalloprotease
SFR_RS06835	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
SFR_RS06840	COG1940	carbohydrate kinase activity
SFR_RS06845	COG1012	belongs to the aldehyde dehydrogenase family
SFR_RS06880	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SFR_RS06885	COG1177	transmembrane transport
SFR_RS06890	COG1176	ABC-type spermidine putrescine transport system, permease component I
SFR_RS06895	COG3842	ATPase activity
SFR_RS06905	COG1012	belongs to the aldehyde dehydrogenase family
SFR_RS06920	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SFR_RS06935	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SFR_RS06940	COG1012	belongs to the aldehyde dehydrogenase family
SFR_RS06950	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SFR_RS06975	COG3842	ATPase activity
SFR_RS06980	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
SFR_RS06990	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SFR_RS06995	COG0575	Belongs to the CDS family
SFR_RS07000	COG0233	cytoplasmic translational termination
SFR_RS07005	COG0528	UMP kinase activity
SFR_RS07010	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SFR_RS07015	COG0052	Belongs to the universal ribosomal protein uS2 family
SFR_RS07030	COG1191	sigma factor activity
SFR_RS07120	COG0629	single-stranded DNA binding
SFR_RS07300	COG0792	nuclease activity
SFR_RS07315	COG0681	Belongs to the peptidase S26 family
SFR_RS07320	COG0681	Belongs to the peptidase S26 family
SFR_RS07325	COG0681	Belongs to the peptidase S26 family
SFR_RS07330	COG0681	Belongs to the peptidase S26 family
SFR_RS07335	COG0335	large ribosomal subunit rRNA binding
SFR_RS07340	COG0336	Belongs to the RNA methyltransferase TrmD family
SFR_RS07345	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SFR_RS07350	COG1837	Belongs to the UPF0109 family
SFR_RS07355	COG0228	four-way junction DNA binding
SFR_RS07370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SFR_RS07380	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
SFR_RS07410	COG0477	Major facilitator Superfamily
SFR_RS07425	COG1254	Belongs to the acylphosphatase family
SFR_RS07430	COG2340	Cysteine-rich secretory protein family
SFR_RS07435	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SFR_RS07440	COG0571	ribonuclease III activity
SFR_RS07445	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SFR_RS07460	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SFR_RS07465	COG0742	ribosomal rna small subunit methyltransferase
SFR_RS07475	COG1461	Dihydroxyacetone kinase
SFR_RS07480	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SFR_RS07485	COG0351	phosphomethylpyrimidine kinase
SFR_RS07505	COG1181	Belongs to the D-alanine--D-alanine ligase family
SFR_RS07510	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SFR_RS07520	COG1920	GTP binding
SFR_RS07530	COG0776	regulation of translation
SFR_RS07540	COG0066	3-isopropylmalate dehydratase activity
SFR_RS07545	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SFR_RS07550	COG1414	Transcriptional regulator
SFR_RS07595	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SFR_RS07600	COG0179	Fumarylacetoacetate (FAA) hydrolase
SFR_RS07615	COG2018	Roadblock/LC7 domain
SFR_RS07640	COG2018	Roadblock/LC7 domain
SFR_RS07660	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SFR_RS07670	COG2353	YceI-like domain
SFR_RS07710	COG0789	Transcriptional regulator
SFR_RS07730	COG4221	oxidoreductase activity
SFR_RS07760	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SFR_RS07770	COG0477	Major facilitator Superfamily
SFR_RS07775	COG2957	Belongs to the agmatine deiminase family
SFR_RS07780	COG0804	urea catabolic process
SFR_RS07785	COG0832	Belongs to the urease beta subunit family
SFR_RS07785	COG0831	urea catabolic process
SFR_RS07790	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SFR_RS07795	COG0473	3-isopropylmalate dehydrogenase activity
SFR_RS07820	COG1012	belongs to the aldehyde dehydrogenase family
SFR_RS07825	COG0506	proline dehydrogenase activity
SFR_RS07830	COG3835	regulator
SFR_RS07850	COG2890	protein-(glutamine-N5) methyltransferase activity
SFR_RS07860	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SFR_RS07865	COG0440	acetolactate synthase activity
SFR_RS07885	COG0667	Aldo Keto reductase
SFR_RS07890	COG2133	pyrroloquinoline quinone binding
SFR_RS07900	COG3293	Transposase
SFR_RS07915	COG2197	response regulator
SFR_RS07930	COG2409	Drug exporters of the RND superfamily
SFR_RS07935	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SFR_RS07945	COG0154	amidase activity
SFR_RS07950	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SFR_RS07960	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SFR_RS07970	COG4221	oxidoreductase activity
SFR_RS07990	COG0482	sulfurtransferase activity
SFR_RS08015	COG2860	membrane
SFR_RS08020	COG4608	Belongs to the ABC transporter superfamily
SFR_RS08025	COG0444	Belongs to the ABC transporter superfamily
SFR_RS08030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SFR_RS08035	COG0601	transmembrane transport
SFR_RS08040	COG0747	negative chemotaxis
SFR_RS08060	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SFR_RS08065	COG0509	glycine decarboxylation via glycine cleavage system
SFR_RS08070	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SFR_RS08075	COG1760	l-serine dehydratase
SFR_RS08090	COG2814	Major facilitator Superfamily
SFR_RS08095	COG2197	response regulator
SFR_RS08100	COG0277	FAD linked oxidase domain protein
SFR_RS08115	COG0475	glutathione-regulated potassium exporter activity
SFR_RS08135	COG1013	pyruvate-flavodoxin oxidoreductase activity
SFR_RS08140	COG4552	Acetyltransferase involved in intracellular survival and related
SFR_RS08155	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
SFR_RS08160	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
SFR_RS08165	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
SFR_RS08180	COG0477	Major facilitator Superfamily
SFR_RS08195	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SFR_RS08220	COG2085	NADP oxidoreductase coenzyme F420-dependent
SFR_RS08245	COG1376	ErfK ybiS ycfS ynhG family protein
SFR_RS08270	COG1132	(ABC) transporter
SFR_RS08275	COG1132	(ABC) transporter
SFR_RS08285	COG1733	regulation of RNA biosynthetic process
SFR_RS08305	COG0366	Alpha amylase catalytic
SFR_RS08310	COG0366	Alpha amylase catalytic
SFR_RS08315	COG3281	Trehalose synthase
SFR_RS08320	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SFR_RS08335	COG1119	ATPase activity
SFR_RS08345	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SFR_RS08360	COG1301	dicarboxylic acid transport
SFR_RS08365	COG3290	protein histidine kinase activity
SFR_RS08370	COG4565	transcriptional regulatory protein
SFR_RS08375	COG0205	6-phosphofructokinase activity
SFR_RS08380	COG0857	belongs to the CobB CobQ family
SFR_RS08380	COG0280	phosphate acetyltransferase
SFR_RS08385	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SFR_RS08430	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SFR_RS08430	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SFR_RS08505	COG1335	isochorismatase
SFR_RS08535	COG0183	Belongs to the thiolase family
SFR_RS08555	COG1131	(ABC) transporter
SFR_RS08590	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
SFR_RS08605	COG1250	3-hydroxyacyl-CoA dehydrogenase
SFR_RS08620	COG4585	Histidine kinase
SFR_RS08625	COG2197	response regulator
SFR_RS08645	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SFR_RS08650	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SFR_RS08655	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SFR_RS08660	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SFR_RS08665	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SFR_RS08670	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SFR_RS08675	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SFR_RS08690	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SFR_RS08695	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SFR_RS08705	COG2890	protein-(glutamine-N5) methyltransferase activity
SFR_RS08710	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SFR_RS08715	COG0254	rRNA binding
SFR_RS08720	COG1316	TRANSCRIPTIONal
SFR_RS08730	COG0083	homoserine kinase activity
SFR_RS08740	COG0019	diaminopimelate decarboxylase activity
SFR_RS08745	COG0018	arginyl-trna synthetase
SFR_RS08770	COG1012	belongs to the aldehyde dehydrogenase family
SFR_RS08780	COG1191	sigma factor activity
SFR_RS08785	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SFR_RS08785	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
SFR_RS08795	COG2267	carboxylic ester hydrolase activity
SFR_RS08800	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
SFR_RS08815	COG0772	Belongs to the SEDS family
SFR_RS08890	COG0726	polysaccharide deacetylase
SFR_RS08895	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SFR_RS08900	COG0477	Major facilitator Superfamily
SFR_RS08915	COG1595	DNA-templated transcription, initiation
SFR_RS08925	COG1131	(ABC) transporter
SFR_RS08945	COG0745	RESPONSE REGULATOR receiver
SFR_RS08950	COG2205	protein histidine kinase activity
SFR_RS08955	COG0508	dehydrogenase complex catalyzes the overall conversion of
SFR_RS08955	COG0567	Dehydrogenase, E1 component
SFR_RS08985	COG2255	four-way junction helicase activity
SFR_RS09030	COG0604	alcohol dehydrogenase
SFR_RS09035	COG0281	malic enzyme
SFR_RS09050	COG1126	abc transporter atp-binding protein
SFR_RS09055	COG4106	trans-aconitate 2-methyltransferase activity
SFR_RS09105	COG0142	geranyltranstransferase activity
SFR_RS09115	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SFR_RS09120	COG1959	2 iron, 2 sulfur cluster binding
SFR_RS09140	COG2515	1-aminocyclopropane-1-carboxylate deaminase
SFR_RS09155	COG2172	sigma factor antagonist activity
SFR_RS09170	COG1597	lipid kinase activity
SFR_RS09185	COG0363	glucosamine-6-phosphate deaminase activity
SFR_RS09190	COG1472	Belongs to the glycosyl hydrolase 3 family
SFR_RS09195	COG0395	ABC-type sugar transport system, permease component
SFR_RS09200	COG1175	transmembrane transport
SFR_RS09205	COG2182	Extracellular solute-binding protein
SFR_RS09210	COG2188	Transcriptional regulator
SFR_RS09215	COG1966	Carbon starvation protein
SFR_RS09235	COG2124	cytochrome p450
SFR_RS09245	COG0242	peptide deformylase activity
SFR_RS09255	COG5662	AntiSigma factor
SFR_RS09260	COG1595	DNA-templated transcription, initiation
SFR_RS09270	COG2135	peptidase activity
SFR_RS09280	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SFR_RS09290	COG2076	Multidrug Resistance protein
SFR_RS09300	COG0483	inositol monophosphate 1-phosphatase activity
SFR_RS09305	COG0753	catalase activity
SFR_RS09330	COG1615	UPF0182 protein
SFR_RS09340	COG3480	Lon protease (S16) C-terminal proteolytic domain
SFR_RS09395	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SFR_RS09435	COG0210	DNA helicase
SFR_RS09530	COG0513	Belongs to the DEAD box helicase family
SFR_RS09540	COG1432	Conserved Protein
SFR_RS09545	COG2095	MarC family integral membrane protein
SFR_RS09550	COG0613	PHP domain protein
SFR_RS09555	COG2814	Major facilitator Superfamily
SFR_RS09565	COG0598	Magnesium transport protein CorA
SFR_RS09605	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SFR_RS09620	COG1595	DNA-templated transcription, initiation
SFR_RS09635	COG1024	Enoyl-CoA hydratase
SFR_RS09645	COG0519	Catalyzes the synthesis of GMP from XMP
SFR_RS09680	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SFR_RS09710	COG0456	acetyltransferase
SFR_RS09715	COG2912	Transglutaminase-like superfamily
SFR_RS09725	COG1609	Transcriptional regulator
SFR_RS09730	COG1172	Belongs to the binding-protein-dependent transport system permease family
SFR_RS09740	COG1129	ABC transporter
SFR_RS09745	COG1879	ABC-type sugar transport system periplasmic component
SFR_RS09750	COG3250	beta-galactosidase activity
SFR_RS09770	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SFR_RS09795	COG4608	Belongs to the ABC transporter superfamily
SFR_RS09805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SFR_RS09810	COG0601	transmembrane transport
SFR_RS09820	COG4608	Belongs to the ABC transporter superfamily
SFR_RS09825	COG0444	Belongs to the ABC transporter superfamily
SFR_RS09830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SFR_RS09835	COG0601	transmembrane transport
SFR_RS09845	COG1217	gtp-binding protein TYPA
SFR_RS09955	COG1028	Short-chain dehydrogenase reductase Sdr
SFR_RS09960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SFR_RS09970	COG3473	Maleate cis-trans isomerase
SFR_RS09990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SFR_RS09995	COG0765	amino acid transport
SFR_RS10000	COG0765	amino acid transport
SFR_RS10005	COG1126	abc transporter atp-binding protein
SFR_RS10035	COG3397	chitin binding
SFR_RS10090	COG0673	inositol 2-dehydrogenase activity
SFR_RS10095	COG0179	Fumarylacetoacetate (FAA) hydrolase
SFR_RS10100	COG0706	membrane insertase activity
SFR_RS10135	COG2271	Major facilitator Superfamily
SFR_RS10140	COG2733	membrane
SFR_RS10170	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SFR_RS10180	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SFR_RS10205	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SFR_RS10210	COG2197	response regulator
SFR_RS10240	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
SFR_RS10245	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SFR_RS10250	COG1263	PTS System
SFR_RS10260	COG1234	tRNA 3'-trailer cleavage
SFR_RS10280	COG1113	amino acid transport
SFR_RS10295	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
SFR_RS10305	COG1335	isochorismatase
SFR_RS10330	COG0745	RESPONSE REGULATOR receiver
SFR_RS10335	COG2205	protein histidine kinase activity
SFR_RS10370	COG0277	FAD linked oxidase domain protein
SFR_RS10380	COG3185	4-Hydroxyphenylpyruvate dioxygenase
SFR_RS10390	COG1174	glycine betaine transport
SFR_RS10395	COG1125	glycine betaine transport
SFR_RS10395	COG0517	IMP dehydrogenase activity
SFR_RS10400	COG1174	glycine betaine transport
SFR_RS10445	COG1116	anion transmembrane transporter activity
SFR_RS10465	COG2318	DinB family
SFR_RS10490	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SFR_RS10515	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SFR_RS10530	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SFR_RS10535	COG0395	ABC-type sugar transport system, permease component
SFR_RS10540	COG1175	transmembrane transport
SFR_RS10555	COG1678	Uncharacterized ACR, COG1678
SFR_RS10560	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SFR_RS10565	COG0776	regulation of translation
SFR_RS10575	COG3973	AAA domain
SFR_RS10575	COG3973	AAA domain
SFR_RS10620	COG0583	DNA-binding transcription factor activity
SFR_RS10635	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SFR_RS10640	COG0793	Belongs to the peptidase S41A family
SFR_RS10650	COG2884	Cell division ATP-binding protein ftsE
SFR_RS10665	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SFR_RS10670	COG0515	serine threonine protein kinase
SFR_RS10675	COG0515	serine threonine protein kinase
SFR_RS10685	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SFR_RS10690	COG1653	transport
SFR_RS10695	COG1175	transmembrane transport
SFR_RS10700	COG0395	ABC-type sugar transport system, permease component
SFR_RS10705	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SFR_RS10710	COG0438	transferase activity, transferring glycosyl groups
SFR_RS10715	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SFR_RS10720	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SFR_RS10730	COG2226	methyltransferase
SFR_RS10745	COG2902	Dehydrogenase
SFR_RS10765	COG0583	DNA-binding transcription factor activity
SFR_RS10780	COG0653	protein targeting
SFR_RS10785	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SFR_RS10790	COG3214	Protein conserved in bacteria
SFR_RS10795	COG2197	response regulator
SFR_RS10800	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SFR_RS10810	COG0823	Involved in the tonB-independent uptake of proteins
SFR_RS10815	COG5002	protein histidine kinase activity
SFR_RS10820	COG0745	RESPONSE REGULATOR receiver
SFR_RS10825	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
SFR_RS10845	COG0714	Associated with various cellular activities
SFR_RS10850	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
SFR_RS10890	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
SFR_RS10900	COG1482	cell wall glycoprotein biosynthetic process
SFR_RS10910	COG2835	tetraacyldisaccharide 4'-kinase activity
SFR_RS10920	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SFR_RS10930	COG1620	l-lactate permease
SFR_RS10965	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SFR_RS10970	COG0778	Nitroreductase
SFR_RS10970	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
SFR_RS11020	COG1316	TRANSCRIPTIONal
SFR_RS11025	COG3046	protein related to deoxyribodipyrimidine photolyase
SFR_RS11080	COG0753	catalase activity
SFR_RS11115	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SFR_RS11125	COG2072	flavoprotein involved in K transport
SFR_RS11150	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SFR_RS11165	COG2205	protein histidine kinase activity
SFR_RS11170	COG0745	RESPONSE REGULATOR receiver
SFR_RS11175	COG3104	oligopeptide transport
SFR_RS11185	COG1366	Belongs to the anti-sigma-factor antagonist family
SFR_RS11190	COG1191	sigma factor activity
SFR_RS11195	COG1228	amidohydrolase
SFR_RS11205	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SFR_RS11225	COG0395	ABC-type sugar transport system, permease component
SFR_RS11295	COG2755	lipolytic protein G-D-S-L family
SFR_RS11300	COG0183	Belongs to the thiolase family
SFR_RS11320	COG1476	TRANSCRIPTIONal
SFR_RS11335	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
SFR_RS11345	COG1136	(ABC) transporter
SFR_RS11350	COG0577	efflux transmembrane transporter activity
SFR_RS11350	COG1136	(ABC) transporter
SFR_RS11355	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SFR_RS11360	COG1252	NADH dehydrogenase
SFR_RS11390	COG0148	phosphopyruvate hydratase activity
SFR_RS11445	COG1733	regulation of RNA biosynthetic process
SFR_RS11490	COG0154	amidase activity
SFR_RS11495	COG3226	Transcriptional regulator
SFR_RS11505	COG1473	amidohydrolase
SFR_RS11560	COG3629	intracellular signal transduction
SFR_RS11560	COG3903	Transcriptional regulator
SFR_RS11610	COG0596	Alpha beta hydrolase
SFR_RS11620	COG1316	TRANSCRIPTIONal
SFR_RS11640	COG0789	Transcriptional regulator
SFR_RS11665	COG4585	Histidine kinase
SFR_RS11675	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SFR_RS11680	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SFR_RS11705	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
SFR_RS11710	COG0193	aminoacyl-tRNA hydrolase activity
SFR_RS11720	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
SFR_RS11740	COG4106	trans-aconitate 2-methyltransferase activity
SFR_RS11750	COG2197	response regulator
SFR_RS11755	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
SFR_RS11800	COG0488	(ABC) transporter
SFR_RS11805	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SFR_RS11810	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SFR_RS11815	COG0084	hydrolase, TatD family'
SFR_RS11900	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SFR_RS11910	COG2409	Drug exporters of the RND superfamily
SFR_RS11920	COG4946	Tricorn protease homolog
SFR_RS11920	COG0793	Belongs to the peptidase S41A family
SFR_RS11930	COG4221	oxidoreductase activity
SFR_RS11940	COG2072	flavoprotein involved in K transport
SFR_RS11950	COG0708	Exodeoxyribonuclease III
SFR_RS11960	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SFR_RS11980	COG2197	response regulator
SFR_RS12025	COG0315	cyclic pyranopterin monophosphate synthase activity
SFR_RS12025	COG0521	Mo-molybdopterin cofactor biosynthetic process
SFR_RS12030	COG0315	cyclic pyranopterin monophosphate synthase activity
SFR_RS12040	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SFR_RS12045	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SFR_RS12055	COG3263	regulation of cellular component size
SFR_RS12080	COG1970	mechanosensitive ion channel activity
SFR_RS12095	COG3191	aminopeptidase activity
SFR_RS12115	COG3384	dioxygenase
SFR_RS12120	COG1846	Transcriptional regulator
SFR_RS12175	COG2050	protein possibly involved in aromatic compounds catabolism
SFR_RS12185	COG0183	Belongs to the thiolase family
SFR_RS12190	COG1024	Enoyl-CoA hydratase
SFR_RS12195	COG1250	3-hydroxyacyl-CoA dehydrogenase
SFR_RS12200	COG3396	Phenylacetate-CoA oxygenase
SFR_RS12205	COG3460	Phenylacetate-CoA oxygenase
SFR_RS12210	COG3396	Phenylacetate-CoA oxygenase
SFR_RS12215	COG2151	metal-sulfur cluster biosynthetic enzyme
SFR_RS12220	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SFR_RS12255	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SFR_RS12270	COG1278	Cold shock
SFR_RS12350	COG5297	Belongs to the glycosyl hydrolase family 6
SFR_RS12375	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SFR_RS12415	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SFR_RS12450	COG0515	serine threonine protein kinase
SFR_RS12450	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SFR_RS12455	COG1309	transcriptional regulator
SFR_RS12475	COG2072	flavoprotein involved in K transport
SFR_RS12480	COG2271	Major facilitator Superfamily
SFR_RS12500	COG1366	Belongs to the anti-sigma-factor antagonist family
SFR_RS12580	COG4821	SIS domain
SFR_RS12590	COG0259	pyridoxamine-phosphate oxidase activity
SFR_RS12610	COG1024	Enoyl-CoA hydratase
SFR_RS12625	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SFR_RS12680	COG0583	DNA-binding transcription factor activity
SFR_RS12690	COG0277	FAD linked oxidase domain protein
SFR_RS12690	COG0247	lactate metabolic process
SFR_RS12695	COG2205	protein histidine kinase activity
SFR_RS12715	COG2124	cytochrome p450
SFR_RS12725	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
SFR_RS12810	COG0667	Aldo Keto reductase
SFR_RS12835	COG2252	PERMEase
SFR_RS12845	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SFR_RS12880	COG2814	Major facilitator Superfamily
SFR_RS12890	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SFR_RS12895	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
SFR_RS12900	COG1278	Cold shock
SFR_RS12910	COG2197	response regulator
SFR_RS12920	COG1132	(ABC) transporter
SFR_RS12930	COG0515	serine threonine protein kinase
SFR_RS12935	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SFR_RS12940	COG1120	ATPase activity
SFR_RS12945	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SFR_RS12950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SFR_RS12970	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SFR_RS12975	COG1295	ribonuclease BN
SFR_RS12985	COG2124	cytochrome p450
SFR_RS13045	COG1061	Type III restriction enzyme res subunit
SFR_RS13085	COG0789	Transcriptional regulator
SFR_RS13120	COG3973	AAA domain
SFR_RS13165	COG4585	Histidine kinase
SFR_RS13170	COG2197	response regulator
SFR_RS13205	COG0406	alpha-ribazole phosphatase activity
SFR_RS13215	COG1737	Transcriptional regulator
SFR_RS13220	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
SFR_RS13225	COG1263	PTS System
SFR_RS13225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SFR_RS13230	COG0667	Aldo Keto reductase
SFR_RS13270	COG1278	Cold shock
SFR_RS13285	COG0463	Glycosyl transferase, family 2
SFR_RS13310	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SFR_RS13375	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SFR_RS13430	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SFR_RS13510	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SFR_RS13580	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
SFR_RS13595	COG1366	Belongs to the anti-sigma-factor antagonist family
SFR_RS13600	COG1366	Belongs to the anti-sigma-factor antagonist family
SFR_RS13605	COG2172	sigma factor antagonist activity
SFR_RS13630	COG0577	efflux transmembrane transporter activity
SFR_RS13630	COG1136	(ABC) transporter
SFR_RS13635	COG0577	efflux transmembrane transporter activity
SFR_RS13645	COG1902	pentaerythritol trinitrate reductase activity
SFR_RS13675	COG2409	Drug exporters of the RND superfamily
SFR_RS13695	COG2197	response regulator
SFR_RS13700	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SFR_RS13705	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SFR_RS13725	COG0301	tRNA thio-modification
SFR_RS13750	COG1278	Cold shock
SFR_RS13780	COG2770	Histidine kinase
SFR_RS13780	COG2208	phosphoserine phosphatase activity
SFR_RS13815	COG0456	acetyltransferase
SFR_RS13825	COG0436	Aminotransferase
SFR_RS13835	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SFR_RS13845	COG3486	L-lysine 6-monooxygenase (NADPH) activity
SFR_RS13855	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SFR_RS13855	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SFR_RS13900	COG2814	Major facilitator Superfamily
SFR_RS13910	COG3842	ATPase activity
SFR_RS13920	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SFR_RS13930	COG1253	flavin adenine dinucleotide binding
SFR_RS13945	COG0215	cysteine-tRNA ligase activity
SFR_RS13960	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SFR_RS13980	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
SFR_RS13985	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
SFR_RS13990	COG1329	Transcriptional regulator
SFR_RS14005	COG0745	RESPONSE REGULATOR receiver
SFR_RS14010	COG5002	protein histidine kinase activity
SFR_RS14020	COG2076	Multidrug Resistance protein
SFR_RS14100	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SFR_RS14140	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SFR_RS14165	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SFR_RS14170	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SFR_RS14205	COG0783	Belongs to the Dps family
SFR_RS14210	COG1120	ATPase activity
SFR_RS14215	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SFR_RS14235	COG5001	Diguanylate cyclase
SFR_RS14250	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
SFR_RS14255	COG0793	Belongs to the peptidase S41A family
SFR_RS14270	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SFR_RS14275	COG1316	TRANSCRIPTIONal
SFR_RS14285	COG0640	Transcriptional regulator
SFR_RS14295	COG1252	NADH dehydrogenase
SFR_RS14350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SFR_RS14360	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
SFR_RS14370	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SFR_RS14395	COG2186	Transcriptional regulator
SFR_RS14410	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SFR_RS14410	COG0825	malonyl-CoA metabolic process
SFR_RS14420	COG0789	Transcriptional regulator
SFR_RS14435	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
SFR_RS14440	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SFR_RS14455	COG0789	Transcriptional regulator
SFR_RS14475	COG1028	Short-chain dehydrogenase reductase Sdr
SFR_RS14490	COG2249	NAD(P)H dehydrogenase (quinone) activity
SFR_RS14510	COG3293	Transposase
SFR_RS14520	COG0537	adenosine 5'-monophosphoramidase activity
SFR_RS14600	COG0270	DNA (cytosine-5-)-methyltransferase activity
SFR_RS14645	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SFR_RS14650	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SFR_RS14650	COG1754	DNA topoisomerase type I activity
SFR_RS14660	COG2890	protein-(glutamine-N5) methyltransferase activity
SFR_RS14675	COG1366	Belongs to the anti-sigma-factor antagonist family
SFR_RS14680	COG1111	helicase
SFR_RS14680	COG1205	dead DEAH box helicase
SFR_RS14740	COG0659	secondary active sulfate transmembrane transporter activity
SFR_RS14745	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SFR_RS14750	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SFR_RS14760	COG2267	carboxylic ester hydrolase activity
SFR_RS14790	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SFR_RS14800	COG0251	oxidation-reduction process
SFR_RS14810	COG0003	Pfam Anion-transporting ATPase
SFR_RS14835	COG1408	metallophosphoesterase
SFR_RS14850	COG1136	(ABC) transporter
SFR_RS14850	COG0577	efflux transmembrane transporter activity
SFR_RS14865	COG2318	DinB family
SFR_RS14890	COG0596	Alpha beta hydrolase
SFR_RS14910	COG2130	NADP-dependent
SFR_RS14955	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SFR_RS14960	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SFR_RS15025	COG1733	regulation of RNA biosynthetic process
SFR_RS15035	COG0666	response to abiotic stimulus
SFR_RS15045	COG4585	Histidine kinase
SFR_RS15050	COG2197	response regulator
SFR_RS15110	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SFR_RS15215	COG0579	oxidoreductase
SFR_RS15220	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SFR_RS15230	COG0667	Aldo Keto reductase
SFR_RS15260	COG0542	response to heat
SFR_RS15290	COG0513	Belongs to the DEAD box helicase family
SFR_RS15325	COG1643	Atp-dependent helicase
SFR_RS15360	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SFR_RS15375	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SFR_RS15380	COG0047	phosphoribosylformylglycinamidine synthase activity
SFR_RS15385	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SFR_RS15420	COG2197	response regulator
SFR_RS15430	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SFR_RS15445	COG0151	Belongs to the GarS family
SFR_RS15470	COG0659	secondary active sulfate transmembrane transporter activity
SFR_RS15480	COG2837	iron assimilation
SFR_RS15485	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SFR_RS15550	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SFR_RS15580	COG1191	sigma factor activity
SFR_RS15585	COG1191	sigma factor activity
SFR_RS15600	COG0477	Major facilitator Superfamily
SFR_RS15620	COG0477	Major facilitator Superfamily
SFR_RS15630	COG0745	RESPONSE REGULATOR receiver
SFR_RS15665	COG0318	PFAM AMP-dependent synthetase and ligase
SFR_RS15670	COG1595	DNA-templated transcription, initiation
SFR_RS15690	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SFR_RS15710	COG0653	protein targeting
SFR_RS15725	COG0006	proline dipeptidase activity
SFR_RS15745	COG1999	signal sequence binding
SFR_RS15760	COG2837	iron assimilation
SFR_RS15765	COG0077	Prephenate dehydratase
SFR_RS15770	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SFR_RS15775	COG0561	phosphatase activity
SFR_RS15795	COG1131	(ABC) transporter
SFR_RS15815	COG0561	phosphatase activity
SFR_RS15820	COG1196	nuclear chromosome segregation
SFR_RS15820	COG0739	heme binding
SFR_RS15820	COG0741	lytic transglycosylase activity
SFR_RS15830	COG4988	ABC transporter
SFR_RS15835	COG1294	oxidase, subunit
SFR_RS15840	COG1271	oxidase subunit
SFR_RS15845	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SFR_RS15850	COG1609	Transcriptional regulator
SFR_RS15865	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
SFR_RS15890	COG0662	Cupin 2, conserved barrel domain protein
SFR_RS15895	COG1950	PFAM Membrane protein of
SFR_RS15900	COG0626	cystathionine gamma-synthase activity
SFR_RS15945	COG0110	maltose O-acetyltransferase activity
SFR_RS15950	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SFR_RS15955	COG0305	Participates in initiation and elongation during chromosome replication
SFR_RS15965	COG0359	binds to the 23S rRNA
SFR_RS15970	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SFR_RS15975	COG0629	single-stranded DNA binding
SFR_RS15980	COG0360	Binds together with S18 to 16S ribosomal RNA
SFR_RS16005	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SFR_RS16035	COG0617	tRNA 3'-terminal CCA addition
SFR_RS16050	COG2815	serine threonine protein kinase
SFR_RS16050	COG0515	serine threonine protein kinase
SFR_RS16055	COG1595	DNA-templated transcription, initiation
SFR_RS16065	COG0492	ferredoxin-NADP+ reductase activity
SFR_RS16070	COG3118	belongs to the thioredoxin family
SFR_RS16085	COG1192	Involved in chromosome partitioning
SFR_RS16090	COG0357	Ribosomal RNA small subunit methyltransferase G
SFR_RS16100	COG0706	membrane insertase activity
SFR_RS16105	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
SFR_RS16110	COG0594	ribonuclease P activity
SFR_RS16115	COG0230	Belongs to the bacterial ribosomal protein bL34 family
SFR_RS16120	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SFR_RS16125	COG0592	DNA-directed DNA polymerase activity
SFR_RS16130	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
SFR_RS16135	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SFR_RS16140	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
SFR_RS16145	COG0187	DNA topoisomerase II activity
SFR_RS16150	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SFR_RS16190	COG0515	serine threonine protein kinase
SFR_RS16220	COG1278	Cold shock
SFR_RS16225	COG1309	transcriptional regulator
SFR_RS16245	COG0705	Rhomboid family
SFR_RS16265	COG3764	Sortase (surface protein transpeptidase)
SFR_RS16270	COG3764	Sortase (surface protein transpeptidase)
SFR_RS16275	COG0515	serine threonine protein kinase
SFR_RS16300	COG1716	ATPase activity
SFR_RS16305	COG1716	ATPase activity
SFR_RS16315	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
SFR_RS16320	COG1733	regulation of RNA biosynthetic process
SFR_RS16360	COG1522	sequence-specific DNA binding
SFR_RS16385	COG0303	'Molybdopterin
SFR_RS16390	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SFR_RS16415	COG0515	serine threonine protein kinase
SFR_RS16420	COG0515	serine threonine protein kinase
SFR_RS16435	COG0022	dehydrogenase e1 component
SFR_RS16440	COG0508	dehydrogenase complex catalyzes the overall conversion of
SFR_RS16500	COG1362	aminopeptidase activity
SFR_RS16520	COG1960	acyl-CoA dehydrogenase activity
SFR_RS16530	COG1741	Belongs to the pirin family
SFR_RS16535	COG0628	permease
SFR_RS16545	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SFR_RS16555	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SFR_RS16595	COG1316	TRANSCRIPTIONal
SFR_RS16610	COG2268	Band 7 protein
SFR_RS16615	COG1937	Protein conserved in bacteria
SFR_RS16620	COG1064	alcohol dehydrogenase
SFR_RS16655	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SFR_RS16675	COG0477	Major facilitator Superfamily
SFR_RS16705	COG0494	nUDIX hydrolase
SFR_RS16730	COG0657	acetylesterase activity
SFR_RS16735	COG2181	nitrate reductase activity
SFR_RS16735	COG0247	lactate metabolic process
SFR_RS16765	COG0717	Belongs to the dCTP deaminase family
SFR_RS16795	COG2814	Major facilitator Superfamily
SFR_RS16805	COG1695	Transcriptional regulator
SFR_RS16875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SFR_RS16880	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SFR_RS16885	COG1120	ATPase activity
SFR_RS16890	COG1404	Belongs to the peptidase S8 family
SFR_RS16895	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
SFR_RS16915	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
SFR_RS16925	COG1131	(ABC) transporter
SFR_RS16930	COG1725	Transcriptional regulator
SFR_RS16965	COG0443	Heat shock 70 kDa protein
SFR_RS16970	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SFR_RS16975	COG0484	heat shock protein binding
SFR_RS16980	COG0789	Transcriptional regulator
SFR_RS17005	COG0477	Major facilitator Superfamily
SFR_RS17020	COG2378	regulation of single-species biofilm formation
SFR_RS17050	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
SFR_RS17065	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SFR_RS17070	COG0191	fructose-bisphosphate aldolase activity
SFR_RS17075	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SFR_RS17080	COG0477	Major facilitator Superfamily
SFR_RS17100	COG3844	kynureninase activity
SFR_RS17115	COG4585	Histidine kinase
SFR_RS17120	COG2197	response regulator
SFR_RS17130	COG1335	isochorismatase
SFR_RS17145	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SFR_RS17160	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SFR_RS17165	COG0798	PFAM Bile acid sodium symporter
SFR_RS17180	COG2267	carboxylic ester hydrolase activity
SFR_RS17185	COG2124	cytochrome p450
SFR_RS17190	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SFR_RS17195	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SFR_RS17200	COG0477	Major facilitator Superfamily
SFR_RS17250	COG0509	glycine decarboxylation via glycine cleavage system
SFR_RS17260	COG2318	DinB family
SFR_RS17280	COG0739	heme binding
SFR_RS17280	COG0741	lytic transglycosylase activity
SFR_RS17280	COG1196	nuclear chromosome segregation
SFR_RS17285	COG0671	phosphoesterase, PA-phosphatase related
SFR_RS17300	COG1028	Short-chain dehydrogenase reductase Sdr
SFR_RS17310	COG1937	Protein conserved in bacteria
SFR_RS17320	COG0306	phosphate transporter
SFR_RS17325	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SFR_RS17345	COG0406	alpha-ribazole phosphatase activity
SFR_RS17345	COG0494	nUDIX hydrolase
SFR_RS17375	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SFR_RS17380	COG2318	DinB family
SFR_RS17425	COG2208	phosphoserine phosphatase activity
SFR_RS17425	COG2770	Histidine kinase
SFR_RS17435	COG0596	Alpha beta hydrolase
SFR_RS17440	COG3903	Transcriptional regulator
SFR_RS17440	COG3629	intracellular signal transduction
SFR_RS17480	COG1595	DNA-templated transcription, initiation
SFR_RS17535	COG2267	carboxylic ester hydrolase activity
SFR_RS17570	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
SFR_RS17580	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
SFR_RS17590	COG1725	Transcriptional regulator
SFR_RS17595	COG4941	Belongs to the sigma-70 factor family
SFR_RS17645	COG0456	acetyltransferase
SFR_RS17650	COG0737	Belongs to the 5'-nucleotidase family
SFR_RS17655	COG0235	Class ii aldolase
SFR_RS17660	COG2160	L-arabinose isomerase activity
SFR_RS17670	COG1609	Transcriptional regulator
SFR_RS17680	COG1129	ABC transporter
SFR_RS17685	COG4214	carbohydrate transport
SFR_RS17700	COG0745	RESPONSE REGULATOR receiver
SFR_RS17705	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SFR_RS17710	COG1609	Transcriptional regulator
SFR_RS17715	COG0745	RESPONSE REGULATOR receiver
SFR_RS17740	COG2897	thiosulfate sulfurtransferase activity
SFR_RS17775	COG3485	protocatechuate 3,4-dioxygenase
SFR_RS17780	COG0735	belongs to the Fur family
SFR_RS17785	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SFR_RS17790	COG1490	D-aminoacyl-tRNA deacylase activity
SFR_RS17805	COG0789	Transcriptional regulator
SFR_RS17890	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SFR_RS17900	COG2226	methyltransferase
SFR_RS17945	COG0791	NLP P60 protein
SFR_RS17945	COG1388	LysM domain
SFR_RS17945	COG3103	Sh3 type 3 domain protein
SFR_RS17955	COG0438	transferase activity, transferring glycosyl groups
SFR_RS17980	COG0588	phosphoglycerate mutase activity
SFR_RS17990	COG2186	Transcriptional regulator
SFR_RS18010	COG0739	heme binding
SFR_RS18025	COG2814	Major facilitator Superfamily
SFR_RS18025	COG0477	Major facilitator Superfamily
SFR_RS18040	COG2159	amidohydrolase
SFR_RS18045	COG2828	Protein conserved in bacteria
SFR_RS18050	COG2186	Transcriptional regulator
SFR_RS18080	COG0501	Belongs to the peptidase M48B family
SFR_RS18085	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SFR_RS18085	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SFR_RS18125	COG1289	transmembrane transporter activity
SFR_RS18150	COG1012	belongs to the aldehyde dehydrogenase family
SFR_RS18155	COG2318	DinB family
SFR_RS18165	COG0655	NAD(P)H dehydrogenase (quinone) activity
SFR_RS18170	COG0789	Transcriptional regulator
SFR_RS18175	COG0586	Pfam SNARE associated Golgi protein
SFR_RS18185	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SFR_RS18190	COG2027	D-alanyl-D-alanine carboxypeptidase
SFR_RS18200	COG0037	tRNA processing
SFR_RS18215	COG0302	gtp cyclohydrolase
SFR_RS18230	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
SFR_RS18245	COG1125	glycine betaine transport
SFR_RS18245	COG0517	IMP dehydrogenase activity
SFR_RS18250	COG1174	glycine betaine transport
SFR_RS18255	COG1174	glycine betaine transport
SFR_RS18260	COG1732	Glycine betaine
SFR_RS18270	COG0477	Major facilitator Superfamily
SFR_RS18285	COG0477	Major facilitator Superfamily
SFR_RS18350	COG1012	belongs to the aldehyde dehydrogenase family
SFR_RS18365	COG4585	Histidine kinase
SFR_RS18370	COG2197	response regulator
SFR_RS18390	COG0649	NAD binding
SFR_RS18405	COG2197	response regulator
SFR_RS18420	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
SFR_RS18425	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SFR_RS18435	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
SFR_RS18455	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
SFR_RS18485	COG0739	heme binding
SFR_RS18490	COG2205	protein histidine kinase activity
SFR_RS18495	COG0745	RESPONSE REGULATOR receiver
SFR_RS18505	COG1595	DNA-templated transcription, initiation
SFR_RS18515	COG0671	phosphoesterase, PA-phosphatase related
SFR_RS18525	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
SFR_RS18560	COG0248	Ppx GppA phosphatase
SFR_RS18570	COG1082	Xylose isomerase domain protein TIM barrel
SFR_RS18580	COG0129	dihydroxy-acid dehydratase activity
SFR_RS18590	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SFR_RS18610	COG1129	ABC transporter
SFR_RS18610	COG0842	Transport permease protein
SFR_RS18620	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SFR_RS18625	COG0180	Tryptophanyl-tRNA synthetase
SFR_RS18660	COG0123	including yeast histone deacetylase and acetoin utilization protein
SFR_RS18715	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
SFR_RS18720	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
SFR_RS18725	COG0181	hydroxymethylbilane synthase activity
SFR_RS18730	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SFR_RS18730	COG1648	precorrin-2 dehydrogenase activity
SFR_RS18735	COG0113	porphobilinogen synthase activity
SFR_RS18755	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SFR_RS18760	COG0018	arginyl-trna synthetase
SFR_RS18765	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
SFR_RS18790	COG1690	Belongs to the RtcB family
SFR_RS18795	COG0659	secondary active sulfate transmembrane transporter activity
SFR_RS18850	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SFR_RS18855	COG0406	alpha-ribazole phosphatase activity
SFR_RS18865	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SFR_RS18870	COG0785	Cytochrome C biogenesis protein
SFR_RS18880	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SFR_RS18895	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
SFR_RS18900	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SFR_RS18905	COG0163	prenyltransferase activity
SFR_RS18915	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SFR_RS18930	COG1301	dicarboxylic acid transport
SFR_RS18945	COG1131	(ABC) transporter
SFR_RS18950	COG3559	Exporter of polyketide antibiotics
SFR_RS18980	COG0183	Belongs to the thiolase family
SFR_RS18990	COG1278	Cold shock
SFR_RS18995	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
SFR_RS19000	COG1674	ftsk spoiiie
SFR_RS19100	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
SFR_RS19160	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SFR_RS19170	COG2226	methyltransferase
SFR_RS19195	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SFR_RS19200	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SFR_RS19205	COG0649	NAD binding
SFR_RS19215	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SFR_RS19225	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SFR_RS19230	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SFR_RS19235	COG0839	Belongs to the complex I subunit 6 family
SFR_RS19240	COG0713	ATP synthesis coupled electron transport
SFR_RS19245	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SFR_RS19255	COG1007	ATP synthesis coupled electron transport
SFR_RS19260	COG0514	ATP-dependent DNA helicase (RecQ)
SFR_RS19275	COG0561	phosphatase activity
SFR_RS19285	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SFR_RS19300	COG3104	oligopeptide transport
SFR_RS19305	COG0142	geranyltranstransferase activity
SFR_RS19325	COG0488	(ABC) transporter
SFR_RS19335	COG0702	epimerase
SFR_RS19340	COG1733	regulation of RNA biosynthetic process
SFR_RS19345	COG1013	pyruvate-flavodoxin oxidoreductase activity
SFR_RS19350	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SFR_RS19350	COG0674	pyruvate-flavodoxin oxidoreductase activity
SFR_RS19355	COG2197	response regulator
SFR_RS19360	COG4585	Histidine kinase
SFR_RS19370	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SFR_RS19375	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SFR_RS19380	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SFR_RS19385	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SFR_RS19390	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SFR_RS19395	COG0839	Belongs to the complex I subunit 6 family
SFR_RS19400	COG0713	ATP synthesis coupled electron transport
SFR_RS19405	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SFR_RS19415	COG1007	ATP synthesis coupled electron transport
SFR_RS19420	COG0501	Belongs to the peptidase M48B family
SFR_RS19425	COG3304	Inner membrane component domain
SFR_RS19430	COG2261	transglycosylase associated protein
SFR_RS19435	COG1666	GTP binding
SFR_RS19450	COG0702	epimerase
SFR_RS19455	COG0402	S-adenosylhomocysteine deaminase activity
SFR_RS19470	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SFR_RS19475	COG2030	dehydratase
SFR_RS19485	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SFR_RS19495	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SFR_RS19500	COG0436	Aminotransferase
SFR_RS19525	COG0081	regulation of translation
SFR_RS19535	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SFR_RS19540	COG0222	ribosome binding
SFR_RS19550	COG0085	RNA polymerase activity
SFR_RS19555	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SFR_RS19590	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SFR_RS19595	COG0049	tRNA binding
SFR_RS19600	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SFR_RS19635	COG1074	ATP-dependent DNA helicase activity
SFR_RS19665	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
SFR_RS19675	COG0051	transcription antitermination factor activity, RNA binding
SFR_RS19680	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SFR_RS19685	COG0088	Forms part of the polypeptide exit tunnel
SFR_RS19690	COG0089	rRNA binding
SFR_RS19695	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SFR_RS19700	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SFR_RS19705	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SFR_RS19710	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SFR_RS19715	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SFR_RS19720	COG0255	Belongs to the universal ribosomal protein uL29 family
SFR_RS19725	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SFR_RS19730	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SFR_RS19735	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SFR_RS19740	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SFR_RS19745	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SFR_RS19755	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SFR_RS19760	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SFR_RS19765	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SFR_RS19770	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SFR_RS19775	COG1841	ribosomal large subunit assembly
SFR_RS19780	COG0200	Binds to the 23S rRNA
SFR_RS19785	COG0201	protein transport
SFR_RS19790	COG0563	adenylate kinase activity
SFR_RS19800	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SFR_RS19805	COG0257	Belongs to the bacterial ribosomal protein bL36 family
SFR_RS19810	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SFR_RS19815	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SFR_RS19825	COG0203	ribosomal protein L17
SFR_RS19830	COG0101	tRNA pseudouridine synthase activity
SFR_RS19840	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SFR_RS19845	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SFR_RS19850	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SFR_RS19855	COG1072	(Pantothenic acid kinase))
SFR_RS19870	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SFR_RS19885	COG4977	sequence-specific DNA binding
SFR_RS19900	COG0736	holo-[acyl-carrier-protein] synthase activity
SFR_RS19965	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SFR_RS19975	COG0802	atpase or kinase
SFR_RS20000	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SFR_RS20035	COG0726	polysaccharide deacetylase
SFR_RS20050	COG4221	oxidoreductase activity
SFR_RS20055	COG0583	DNA-binding transcription factor activity
SFR_RS20065	COG2197	response regulator
SFR_RS20070	COG1595	DNA-templated transcription, initiation
SFR_RS20080	COG0516	GMP reductase activity
SFR_RS20090	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SFR_RS20125	COG1012	belongs to the aldehyde dehydrogenase family
SFR_RS20145	COG0519	Catalyzes the synthesis of GMP from XMP
SFR_RS20145	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SFR_RS20155	COG1028	Short-chain dehydrogenase reductase Sdr
SFR_RS20195	COG2197	response regulator
SFR_RS20200	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SFR_RS20245	COG0456	acetyltransferase
SFR_RS20245	COG1846	Transcriptional regulator
SFR_RS20255	COG1228	amidohydrolase
SFR_RS20275	COG0791	NLP P60 protein
SFR_RS20315	COG2066	Belongs to the glutaminase family
SFR_RS20320	COG0741	lytic transglycosylase activity
SFR_RS20320	COG0739	heme binding
SFR_RS20320	COG1196	nuclear chromosome segregation
SFR_RS20325	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
SFR_RS20330	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SFR_RS20330	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SFR_RS20345	COG0714	Associated with various cellular activities
SFR_RS20350	COG2425	protein containing a von Willebrand factor type A (vWA) domain
SFR_RS20355	COG3552	Protein containing von Willebrand factor type A (VWA) domain
SFR_RS20360	COG0045	succinate-CoA ligase (ADP-forming) activity
SFR_RS20390	COG0138	bifunctional purine biosynthesis protein purh
SFR_RS20400	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SFR_RS20425	COG0039	L-malate dehydrogenase activity
SFR_RS20445	COG1012	belongs to the aldehyde dehydrogenase family
SFR_RS20455	COG0517	IMP dehydrogenase activity
SFR_RS20455	COG4175	Glycine betaine
SFR_RS20485	COG0395	ABC-type sugar transport system, permease component
SFR_RS20490	COG1175	transmembrane transport
SFR_RS20510	COG2362	D-Aminopeptidase
SFR_RS20515	COG1609	Transcriptional regulator
SFR_RS20525	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SFR_RS20530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SFR_RS20540	COG0754	glutathionylspermidine amidase activity
SFR_RS20555	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SFR_RS20590	COG0180	Tryptophanyl-tRNA synthetase
SFR_RS20635	COG1295	ribonuclease BN
SFR_RS20650	COG1408	metallophosphoesterase
SFR_RS20675	COG1309	transcriptional regulator
SFR_RS20690	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SFR_RS20695	COG1053	succinate dehydrogenase
SFR_RS20705	COG2009	succinate dehydrogenase
SFR_RS20745	COG1215	transferase activity, transferring glycosyl groups
SFR_RS20750	COG1595	DNA-templated transcription, initiation
SFR_RS20820	COG1216	Glycosyl transferase, family 2
SFR_RS20830	COG1083	cytidylyl-transferase
SFR_RS20835	COG2089	acid synthase
SFR_RS20845	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SFR_RS20845	COG1473	amidohydrolase
SFR_RS20860	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SFR_RS20890	COG1744	ABC transporter substrate-binding protein PnrA-like
SFR_RS20895	COG3845	ABC transporter
SFR_RS20900	COG4603	Belongs to the binding-protein-dependent transport system permease family
SFR_RS20905	COG1079	Belongs to the binding-protein-dependent transport system permease family
SFR_RS20945	COG2814	Major facilitator Superfamily
SFR_RS20950	COG0583	DNA-binding transcription factor activity
SFR_RS20975	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SFR_RS21000	COG2205	protein histidine kinase activity
SFR_RS21005	COG0745	RESPONSE REGULATOR receiver
SFR_RS21010	COG1595	DNA-templated transcription, initiation
SFR_RS21055	COG1012	belongs to the aldehyde dehydrogenase family
SFR_RS21075	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SFR_RS21110	COG4770	biotin carboxylase activity
SFR_RS21120	COG0424	maF-like protein
SFR_RS21130	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SFR_RS21140	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SFR_RS21145	COG1024	Enoyl-CoA hydratase
SFR_RS21155	COG2986	histidine ammonia-lyase
SFR_RS21175	COG1136	(ABC) transporter
SFR_RS21180	COG1064	alcohol dehydrogenase
SFR_RS21185	COG2318	DinB family
SFR_RS21210	COG2255	four-way junction helicase activity
SFR_RS21215	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SFR_RS21230	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SFR_RS21240	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SFR_RS21275	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SFR_RS21295	COG1331	Highly conserved protein containing a thioredoxin domain
SFR_RS21315	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
SFR_RS21345	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
SFR_RS21360	COG1414	Transcriptional regulator
SFR_RS21365	COG0251	oxidation-reduction process
SFR_RS21435	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SFR_RS21470	COG2894	cell division
SFR_RS21535	COG2814	Major facilitator Superfamily
SFR_RS21540	COG0656	L-ascorbic acid biosynthetic process
SFR_RS21545	COG2304	oxidoreductase activity
SFR_RS21555	COG3548	integral membrane protein
SFR_RS21570	COG0667	Aldo Keto reductase
SFR_RS21575	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SFR_RS21580	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
SFR_RS21600	COG0450	alkyl hydroperoxide reductase
SFR_RS21605	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SFR_RS21615	COG1136	(ABC) transporter
SFR_RS21635	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SFR_RS21650	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SFR_RS21660	COG0114	fumarate hydratase activity
SFR_RS21670	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
SFR_RS21670	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
SFR_RS21685	COG0515	serine threonine protein kinase
SFR_RS21710	COG0778	Nitroreductase
SFR_RS21715	COG1722	exodeoxyribonuclease VII activity
SFR_RS21720	COG1570	exodeoxyribonuclease VII activity
SFR_RS21725	COG0531	amino acid
SFR_RS21730	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
SFR_RS21745	COG0012	GTP binding
SFR_RS21775	COG0709	Synthesizes selenophosphate from selenide and ATP
SFR_RS21805	COG0406	alpha-ribazole phosphatase activity
SFR_RS21830	COG0745	RESPONSE REGULATOR receiver
SFR_RS21845	COG2985	domain, Protein
SFR_RS21890	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
SFR_RS21895	COG4977	sequence-specific DNA binding
SFR_RS21910	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SFR_RS21935	COG3486	L-lysine 6-monooxygenase (NADPH) activity
SFR_RS21965	COG1028	Short-chain dehydrogenase reductase Sdr
SFR_RS21975	COG3655	Transcriptional regulator
SFR_RS22010	COG1960	acyl-CoA dehydrogenase activity
SFR_RS22025	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SFR_RS22030	COG1309	transcriptional regulator
SFR_RS22040	COG1946	Acyl-CoA thioesterase
SFR_RS22060	COG1011	Hydrolase
SFR_RS22085	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SFR_RS22095	COG3960	tartronate-semialdehyde synthase activity
SFR_RS22115	COG1472	Belongs to the glycosyl hydrolase 3 family
SFR_RS22120	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SFR_RS22165	COG3718	enzyme involved in inositol metabolism
SFR_RS22170	COG3962	Belongs to the TPP enzyme family
SFR_RS22185	COG1131	(ABC) transporter
SFR_RS22215	COG3903	Transcriptional regulator
SFR_RS22215	COG3629	intracellular signal transduction
SFR_RS22240	COG0483	inositol monophosphate 1-phosphatase activity
SFR_RS22250	COG1940	carbohydrate kinase activity
SFR_RS22255	COG0395	ABC-type sugar transport system, permease component
SFR_RS22270	COG1063	alcohol dehydrogenase
SFR_RS22275	COG1082	Xylose isomerase domain protein TIM barrel
SFR_RS22280	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
SFR_RS22335	COG0629	single-stranded DNA binding
SFR_RS22370	COG1136	(ABC) transporter
SFR_RS22390	COG0667	Aldo Keto reductase
SFR_RS22395	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SFR_RS22425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SFR_RS22445	COG1486	melibiose metabolic process
SFR_RS22455	COG0668	transmembrane transport
SFR_RS22470	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SFR_RS22490	COG0583	DNA-binding transcription factor activity
SFR_RS22530	COG4266	Belongs to the allantoicase family
SFR_RS22565	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
SFR_RS22570	COG0076	glutamate decarboxylase activity
SFR_RS22575	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SFR_RS22580	COG1113	amino acid transport
SFR_RS22585	COG1113	amino acid transport
SFR_RS22590	COG1268	BioY protein
SFR_RS22595	COG1113	amino acid transport
SFR_RS22610	COG4552	Acetyltransferase involved in intracellular survival and related
SFR_RS22620	COG0475	glutathione-regulated potassium exporter activity
SFR_RS22625	COG3594	Acyltransferase
SFR_RS22645	COG0544	peptidyl-prolyl cis-trans isomerase activity
SFR_RS22650	COG0740	serine-type endopeptidase activity
SFR_RS22655	COG0740	serine-type endopeptidase activity
SFR_RS22660	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SFR_RS22670	COG0525	valine-tRNA ligase activity
SFR_RS22675	COG0285	dihydrofolate synthase activity
SFR_RS22685	COG0105	UTP biosynthetic process
SFR_RS22690	COG1077	Cell shape determining protein MreB Mrl
SFR_RS22710	COG0772	Belongs to the SEDS family
SFR_RS22735	COG1530	ribonuclease E activity
SFR_RS22740	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SFR_RS22745	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SFR_RS22750	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SFR_RS22770	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SFR_RS22780	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SFR_RS22800	COG0501	Belongs to the peptidase M48B family
SFR_RS22805	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SFR_RS22815	COG0799	negative regulation of ribosome biogenesis
SFR_RS22820	COG0588	phosphoglycerate mutase activity
SFR_RS22845	COG0495	leucyl-tRNA aminoacylation
SFR_RS22855	COG1307	EDD domain protein, DegV family
SFR_RS22870	COG2353	YceI-like domain
SFR_RS22885	COG0268	Binds directly to 16S ribosomal RNA
SFR_RS22890	COG0481	GTPase activity
SFR_RS22925	COG0484	heat shock protein binding
SFR_RS22940	COG4946	Tricorn protease homolog
SFR_RS22940	COG0793	Belongs to the peptidase S41A family
SFR_RS22945	COG0537	adenosine 5'-monophosphoramidase activity
SFR_RS22950	COG1234	tRNA 3'-trailer cleavage
SFR_RS22970	COG2515	1-aminocyclopropane-1-carboxylate deaminase
SFR_RS22975	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SFR_RS23000	COG1486	melibiose metabolic process
SFR_RS23005	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SFR_RS23025	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SFR_RS23035	COG2315	Protein conserved in bacteria
SFR_RS23045	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SFR_RS23060	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SFR_RS23075	COG1381	Involved in DNA repair and RecF pathway recombination
SFR_RS23080	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SFR_RS23090	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SFR_RS23095	COG1121	(ABC) transporter
SFR_RS23105	COG0423	glycine-tRNA ligase activity
SFR_RS23150	COG0189	ligase activity
SFR_RS23160	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SFR_RS23175	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SFR_RS23180	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
SFR_RS23190	COG3467	pyridoxamine 5'-phosphate
SFR_RS23200	COG0151	Belongs to the GarS family
SFR_RS23215	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
SFR_RS23220	COG1940	carbohydrate kinase activity
SFR_RS23220	COG1846	Transcriptional regulator
SFR_RS23230	COG0574	Belongs to the PEP-utilizing enzyme family
SFR_RS23230	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SFR_RS23245	COG1324	tolerance protein
SFR_RS23255	COG0829	nickel cation binding
SFR_RS23260	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SFR_RS23265	COG0830	nickel cation binding
SFR_RS23270	COG0804	urea catabolic process
SFR_RS23275	COG0832	Belongs to the urease beta subunit family
SFR_RS23285	COG0738	Major facilitator superfamily
SFR_RS23290	COG1028	Short-chain dehydrogenase reductase Sdr
SFR_RS23305	COG2226	methyltransferase
SFR_RS23345	COG1070	Carbohydrate kinase
SFR_RS23365	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SFR_RS23370	COG0358	DNA primase activity
SFR_RS23380	COG3290	protein histidine kinase activity
SFR_RS23385	COG4565	transcriptional regulatory protein
SFR_RS23390	COG2851	Citrate transporter
SFR_RS23400	COG0232	Belongs to the dGTPase family. Type 2 subfamily
SFR_RS23425	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SFR_RS23450	COG1028	Short-chain dehydrogenase reductase Sdr
SFR_RS23465	COG2890	protein-(glutamine-N5) methyltransferase activity
SFR_RS23480	COG1077	Cell shape determining protein MreB Mrl
SFR_RS23505	COG2130	NADP-dependent
SFR_RS23510	COG1764	response to oxidative stress
SFR_RS23540	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SFR_RS23545	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SFR_RS23550	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SFR_RS23565	COG1741	Belongs to the pirin family
SFR_RS23580	COG0789	Transcriptional regulator
SFR_RS23585	COG0667	Aldo Keto reductase
SFR_RS23600	COG2197	response regulator
SFR_RS23605	COG4585	Histidine kinase
SFR_RS23625	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
SFR_RS23665	COG1196	nuclear chromosome segregation
SFR_RS23705	COG1056	cytidyltransferase-related domain
SFR_RS23705	COG1051	belongs to the nudix hydrolase family
SFR_RS23715	COG2186	Transcriptional regulator
SFR_RS23720	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
SFR_RS23765	COG1358	cellular component organization or biogenesis
SFR_RS23780	COG0586	Pfam SNARE associated Golgi protein
SFR_RS23885	COG3845	ABC transporter
SFR_RS23905	COG0438	transferase activity, transferring glycosyl groups
SFR_RS23935	COG0477	Major facilitator Superfamily
SFR_RS23940	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SFR_RS23945	COG1960	acyl-CoA dehydrogenase activity
SFR_RS23960	COG2197	response regulator
SFR_RS23965	COG0346	lactoylglutathione lyase activity
SFR_RS23970	COG4585	Histidine kinase
SFR_RS23980	COG1131	(ABC) transporter
SFR_RS23990	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
SFR_RS24005	COG0800	Aldolase
SFR_RS24010	COG3022	response to hydroperoxide
SFR_RS24050	COG1733	regulation of RNA biosynthetic process
SFR_RS24070	COG2226	methyltransferase
SFR_RS24075	COG0384	phenazine biosynthesis protein PhzF
SFR_RS24095	COG0076	glutamate decarboxylase activity
SFR_RS24110	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SFR_RS24120	COG1834	amidinotransferase
SFR_RS24140	COG1120	ATPase activity
SFR_RS24145	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SFR_RS24150	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SFR_RS24195	COG1994	Peptidase M50
SFR_RS24200	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
SFR_RS24215	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SFR_RS24215	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SFR_RS24220	COG2132	Multicopper oxidase
SFR_RS24240	COG0174	glutamine synthetase
SFR_RS24320	COG0174	glutamine synthetase
SFR_RS24340	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
SFR_RS24355	COG0531	amino acid
SFR_RS24360	COG1228	amidohydrolase
SFR_RS24375	COG1609	Transcriptional regulator
SFR_RS24380	COG2182	Extracellular solute-binding protein
SFR_RS24385	COG1175	transmembrane transport
SFR_RS24390	COG0395	ABC-type sugar transport system, permease component
SFR_RS24395	COG0366	Alpha amylase catalytic
SFR_RS24415	COG0456	acetyltransferase
SFR_RS24415	COG0454	-acetyltransferase
SFR_RS24420	COG1309	transcriptional regulator
SFR_RS24460	COG0745	RESPONSE REGULATOR receiver
SFR_RS24495	COG1012	belongs to the aldehyde dehydrogenase family
SFR_RS24555	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SFR_RS24560	COG2326	polyphosphate kinase activity
SFR_RS24570	COG2376	Dihydroxyacetone kinase
SFR_RS24580	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SFR_RS24620	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SFR_RS24625	COG0321	lipoyl(octanoyl) transferase activity
SFR_RS24635	COG0456	acetyltransferase
SFR_RS24660	COG4221	oxidoreductase activity
SFR_RS24675	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
SFR_RS24690	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SFR_RS24695	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SFR_RS24700	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
SFR_RS24710	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SFR_RS24755	COG2197	response regulator
SFR_RS24760	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SFR_RS24765	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
SFR_RS24785	COG3293	Transposase
SFR_RS24800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SFR_RS24805	COG1104	cysteine desulfurase activity
SFR_RS24810	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
SFR_RS24815	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SFR_RS24825	COG1376	ErfK ybiS ycfS ynhG family protein
SFR_RS24835	COG1845	cytochrome c oxidase, subunit III
SFR_RS24840	COG2010	Cytochrome c
SFR_RS24845	COG0723	plastoquinol--plastocyanin reductase activity
SFR_RS24850	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SFR_RS24855	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SFR_RS24860	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SFR_RS24865	COG1929	Belongs to the glycerate kinase type-1 family
SFR_RS24875	COG0745	RESPONSE REGULATOR receiver
SFR_RS24880	COG5002	protein histidine kinase activity
SFR_RS24895	COG0705	Rhomboid family
SFR_RS24930	COG0438	transferase activity, transferring glycosyl groups
SFR_RS24950	COG0003	Pfam Anion-transporting ATPase
SFR_RS24960	COG1940	carbohydrate kinase activity
SFR_RS24985	COG4585	Histidine kinase
SFR_RS24990	COG2197	response regulator
SFR_RS24995	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SFR_RS25005	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
SFR_RS25010	COG0243	molybdopterin cofactor binding
SFR_RS25015	COG2193	ferroxidase activity
SFR_RS25020	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SFR_RS25025	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
SFR_RS25030	COG2815	serine threonine protein kinase
SFR_RS25030	COG0515	serine threonine protein kinase
SFR_RS25035	COG2022	thiamine diphosphate biosynthetic process
SFR_RS25045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SFR_RS25045	COG2022	thiamine diphosphate biosynthetic process
SFR_RS25060	COG0352	thiamine-phosphate diphosphorylase activity
SFR_RS25080	COG1309	transcriptional regulator
SFR_RS25090	COG1129	ABC transporter
SFR_RS25095	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SFR_RS25115	COG0714	Associated with various cellular activities
SFR_RS25125	COG0275	rRNA processing
SFR_RS25135	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SFR_RS25145	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SFR_RS25150	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SFR_RS25160	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SFR_RS25165	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
SFR_RS25170	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SFR_RS25175	COG1496	oxidoreductase activity
SFR_RS25185	COG1799	cell septum assembly
SFR_RS25195	COG3599	regulation of cell shape
SFR_RS25205	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SFR_RS25215	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SFR_RS25225	COG2153	protein acetylation
SFR_RS25240	COG0515	serine threonine protein kinase
SFR_RS25260	COG0587	DNA-directed DNA polymerase activity
SFR_RS25265	COG1432	Conserved Protein
SFR_RS25285	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SFR_RS25305	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SFR_RS25310	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SFR_RS25315	COG0131	Imidazoleglycerol-phosphate dehydratase
SFR_RS25320	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SFR_RS25325	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SFR_RS25330	COG0251	oxidation-reduction process
SFR_RS25335	COG0107	imidazoleglycerol-phosphate synthase activity
SFR_RS25340	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SFR_RS25350	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SFR_RS25380	COG0134	indole-3-glycerol-phosphate synthase activity
SFR_RS25385	COG0133	tryptophan synthase activity
SFR_RS25390	COG0159	tryptophan synthase activity
SFR_RS25400	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SFR_RS25410	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SFR_RS25415	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SFR_RS25435	COG1397	ADP-ribosylglycohydrolase
SFR_RS25445	COG0067	glutamate synthase
SFR_RS25445	COG0069	glutamate synthase activity
SFR_RS25445	COG0070	glutamate synthase
SFR_RS25460	COG1278	Cold shock
SFR_RS25465	COG0513	Belongs to the DEAD box helicase family
SFR_RS25475	COG1605	Chorismate mutase
SFR_RS25475	COG0287	Prephenate dehydrogenase
SFR_RS25505	COG3486	L-lysine 6-monooxygenase (NADPH) activity
SFR_RS25550	COG0559	Belongs to the binding-protein-dependent transport system permease family
SFR_RS25560	COG2746	aminoglycoside 3-N-acetyltransferase activity
SFR_RS25565	COG2050	protein possibly involved in aromatic compounds catabolism
SFR_RS25585	COG1643	Atp-dependent helicase
SFR_RS25590	COG2226	methyltransferase
SFR_RS25610	COG0237	dephospho-CoA kinase activity
SFR_RS25640	COG1288	antiporter activity
SFR_RS25690	COG0477	Major facilitator Superfamily
SFR_RS25700	COG0584	glycerophosphoryl diester phosphodiesterase
SFR_RS25710	COG0556	nucleotide-excision repair
SFR_RS25730	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
SFR_RS25735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SFR_RS25745	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SFR_RS25760	COG0322	excinuclease ABC activity
SFR_RS25765	COG1660	Displays ATPase and GTPase activities
SFR_RS25775	COG1481	regulation of sporulation
SFR_RS25780	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SFR_RS25785	COG0126	phosphoglycerate kinase activity
SFR_RS25790	COG0149	triose-phosphate isomerase activity
SFR_RS25795	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SFR_RS25805	COG0166	Belongs to the GPI family
SFR_RS25810	COG0363	glucosamine-6-phosphate deaminase activity
SFR_RS25825	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SFR_RS25830	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SFR_RS25835	COG0109	protoheme IX farnesyltransferase activity
SFR_RS25860	COG1131	(ABC) transporter
SFR_RS25875	COG0719	Fe-S assembly protein
SFR_RS25885	COG0396	ATPase activity
SFR_RS25890	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SFR_RS25895	COG0822	iron-sulfur transferase activity
SFR_RS25905	COG2171	N-acyltransferase activity
SFR_RS25940	COG2197	response regulator
SFR_RS25945	COG4585	Histidine kinase
SFR_RS25975	COG1902	pentaerythritol trinitrate reductase activity
SFR_RS25980	COG5285	phytanoyl-CoA dioxygenase
SFR_RS25985	COG1917	Cupin 2, conserved barrel domain protein
SFR_RS25995	COG0456	acetyltransferase
SFR_RS26030	COG1797	cobyrinic acid a,c-diamide synthase activity
SFR_RS26045	COG1492	cobalamin metabolic process
SFR_RS26050	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
SFR_RS26065	COG0235	Class ii aldolase
SFR_RS26085	COG0488	(ABC) transporter
SFR_RS26095	COG1024	Enoyl-CoA hydratase
SFR_RS26140	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SFR_RS26160	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SFR_RS26175	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SFR_RS26180	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SFR_RS26190	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
SFR_RS26210	COG2261	transglycosylase associated protein
SFR_RS26215	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SFR_RS26225	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
SFR_RS26235	COG2186	Transcriptional regulator
SFR_RS26240	COG2807	transmembrane transport
SFR_RS26250	COG3293	Transposase
SFR_RS26265	COG3830	Belongs to the UPF0237 family
SFR_RS26265	COG0560	Phosphoserine phosphatase
SFR_RS26270	COG1716	ATPase activity
SFR_RS26270	COG0842	Transport permease protein
SFR_RS26270	COG1131	(ABC) transporter
SFR_RS26280	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SFR_RS26295	COG2197	response regulator
SFR_RS26310	COG1119	ATPase activity
SFR_RS26330	COG1881	PFAM PEBP family protein
SFR_RS26340	COG2094	Belongs to the DNA glycosylase MPG family
SFR_RS26380	COG0647	UMP catabolic process
SFR_RS26400	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SFR_RS26405	COG0497	DNA recombination
SFR_RS26425	COG3896	Chloramphenicol phosphotransferase-like protein
SFR_RS26440	COG3387	PFAM Glycoside hydrolase 15-related
SFR_RS26445	COG0504	CTP synthase activity
SFR_RS26450	COG0494	nUDIX hydrolase
SFR_RS26460	COG0686	Belongs to the AlaDH PNT family
SFR_RS26475	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
SFR_RS26480	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
SFR_RS26485	COG1187	pseudouridine synthase activity
SFR_RS26495	COG1397	ADP-ribosylglycohydrolase
SFR_RS26500	COG3541	Predicted nucleotidyltransferase
SFR_RS26515	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
SFR_RS26525	COG1160	GTP binding
SFR_RS26545	COG0438	transferase activity, transferring glycosyl groups
SFR_RS26565	COG0671	phosphoesterase, PA-phosphatase related
SFR_RS26575	COG0477	Major facilitator Superfamily
SFR_RS26580	COG1799	cell septum assembly
SFR_RS26595	COG0765	amino acid transport
SFR_RS26605	COG0765	amino acid transport
SFR_RS26615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SFR_RS26620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SFR_RS26640	COG0330	HflC and HflK could
SFR_RS26655	COG0587	DNA-directed DNA polymerase activity
SFR_RS26660	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SFR_RS26720	COG1216	Glycosyl transferase, family 2
SFR_RS26740	COG2755	lipolytic protein G-D-S-L family
SFR_RS26760	COG3973	AAA domain
SFR_RS26770	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
SFR_RS26790	COG1309	transcriptional regulator
SFR_RS26840	COG3876	Protein conserved in bacteria
SFR_RS26850	COG0488	(ABC) transporter
SFR_RS26865	COG0318	PFAM AMP-dependent synthetase and ligase
SFR_RS26875	COG1960	acyl-CoA dehydrogenase activity
SFR_RS26895	COG2149	membrane
SFR_RS26900	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
SFR_RS26940	COG3265	gluconokinase activity
SFR_RS26950	COG3012	SEC-C Motif Domain Protein
SFR_RS26955	COG3189	MarR family transcriptional regulator
SFR_RS26965	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SFR_RS26995	COG0667	Aldo Keto reductase
SFR_RS27000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SFR_RS27010	COG0598	Magnesium transport protein CorA
SFR_RS27030	COG0215	cysteine-tRNA ligase activity
SFR_RS27045	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SFR_RS27050	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SFR_RS27055	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SFR_RS27065	COG1410	methionine synthase
SFR_RS27065	COG0646	methionine synthase
SFR_RS27075	COG0747	negative chemotaxis
SFR_RS27080	COG2197	response regulator
SFR_RS27090	COG1994	Peptidase M50
SFR_RS27090	COG0517	IMP dehydrogenase activity
SFR_RS27115	COG1222	aaa ATPase
SFR_RS27120	COG4122	O-methyltransferase activity
SFR_RS27130	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SFR_RS27135	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SFR_RS27150	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SFR_RS27185	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SFR_RS27190	COG0805	protein transport
SFR_RS27205	COG2124	cytochrome p450
SFR_RS27235	COG0564	pseudouridine synthase activity
SFR_RS27245	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SFR_RS27255	COG1595	DNA-templated transcription, initiation
SFR_RS27265	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SFR_RS27270	COG0517	IMP dehydrogenase activity
SFR_RS27270	COG4175	Glycine betaine
SFR_RS27295	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SFR_RS27300	COG0531	amino acid
SFR_RS27305	COG2186	Transcriptional regulator
SFR_RS27310	COG0174	glutamine synthetase
SFR_RS27315	COG1012	belongs to the aldehyde dehydrogenase family
SFR_RS27350	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SFR_RS27360	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SFR_RS27365	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SFR_RS27370	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SFR_RS27375	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SFR_RS27380	COG5002	protein histidine kinase activity
SFR_RS27385	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SFR_RS27390	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SFR_RS27390	COG0072	phenylalanine-tRNA ligase activity
SFR_RS27420	COG0697	spore germination
SFR_RS27425	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SFR_RS27465	COG2838	Isocitrate dehydrogenase
SFR_RS27480	COG1309	transcriptional regulator
SFR_RS27495	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SFR_RS27530	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SFR_RS27535	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
SFR_RS27540	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SFR_RS27545	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SFR_RS27550	COG1438	arginine binding
SFR_RS27555	COG4585	Histidine kinase
SFR_RS27560	COG2197	response regulator
SFR_RS27570	COG2409	Drug exporters of the RND superfamily
SFR_RS27575	COG0385	Bile acid
SFR_RS27585	COG0165	Argininosuccinate lyase
SFR_RS27605	COG0477	Major facilitator Superfamily
SFR_RS27610	COG0204	Acyl-transferase
SFR_RS27610	COG0318	PFAM AMP-dependent synthetase and ligase
SFR_RS27615	COG0584	glycerophosphoryl diester phosphodiesterase
SFR_RS27640	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SFR_RS27645	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SFR_RS27650	COG2011	ABC-type metal ion transport system permease component
SFR_RS27655	COG1464	Belongs to the NlpA lipoprotein family
SFR_RS27660	COG1464	Belongs to the NlpA lipoprotein family
SFR_RS27675	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SFR_RS27680	COG1648	precorrin-2 dehydrogenase activity
SFR_RS27680	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SFR_RS27755	COG0456	acetyltransferase
SFR_RS27810	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SFR_RS27815	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SFR_RS27830	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SFR_RS27835	COG1560	Kdo2-lipid A biosynthetic process
SFR_RS27840	COG0438	transferase activity, transferring glycosyl groups
SFR_RS27850	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
SFR_RS27855	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
SFR_RS27860	COG0217	transcriptional regulatory protein
SFR_RS27865	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
SFR_RS27870	COG0632	four-way junction helicase activity
SFR_RS27875	COG2255	four-way junction helicase activity
SFR_RS27885	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SFR_RS27890	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SFR_RS27895	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SFR_RS27900	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SFR_RS27910	COG1196	nuclear chromosome segregation
SFR_RS27915	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SFR_RS27925	COG0124	histidyl-tRNA synthetase
SFR_RS27940	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SFR_RS27955	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SFR_RS27960	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SFR_RS27965	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SFR_RS27970	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SFR_RS27975	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SFR_RS27980	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SFR_RS27985	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SFR_RS27995	COG0006	proline dipeptidase activity
SFR_RS28000	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SFR_RS28005	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SFR_RS28015	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
SFR_RS28020	COG0540	Belongs to the ATCase OTCase family
SFR_RS28025	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SFR_RS28035	COG0505	Belongs to the CarA family
SFR_RS28040	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SFR_RS28045	COG0167	dihydroorotate dehydrogenase activity
SFR_RS28050	COG0284	orotidine-5'-phosphate decarboxylase activity
SFR_RS28065	COG1758	RNA polymerase activity
SFR_RS28075	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SFR_RS28110	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SFR_RS28125	COG2318	DinB family
SFR_RS28130	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SFR_RS28135	COG2390	Transcriptional regulator
SFR_RS28175	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SFR_RS28195	COG0697	spore germination
SFR_RS28200	COG2233	PERMEase
SFR_RS28210	COG0738	Major facilitator superfamily
SFR_RS28215	COG1940	carbohydrate kinase activity
SFR_RS28215	COG1846	Transcriptional regulator
SFR_RS28220	COG1090	epimerase
SFR_RS28235	COG3201	nicotinamide mononucleotide transporter
SFR_RS28240	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SFR_RS28240	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SFR_RS28245	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
SFR_RS28250	COG0140	phosphoribosyl-ATP diphosphatase activity
SFR_RS28255	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SFR_RS28285	COG1960	acyl-CoA dehydrogenase activity
SFR_RS28310	COG0463	Glycosyl transferase, family 2
SFR_RS28315	COG3030	protein affecting phage T7 exclusion by the F plasmid
SFR_RS28325	COG2270	Major facilitator Superfamily
SFR_RS28335	COG2364	Membrane
SFR_RS28340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SFR_RS28430	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
SFR_RS28450	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SFR_RS28460	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SFR_RS28495	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SFR_RS28515	COG1716	ATPase activity
SFR_RS28535	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SFR_RS28545	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SFR_RS28545	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SFR_RS28585	COG1185	polyribonucleotide nucleotidyltransferase activity
SFR_RS28605	COG0697	spore germination
SFR_RS28620	COG0697	spore germination
SFR_RS28640	COG4251	negative regulation of phosphorylation
SFR_RS28690	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SFR_RS28740	COG1982	Orn Lys Arg decarboxylase major
SFR_RS28750	COG1968	undecaprenyl-diphosphatase activity
SFR_RS28770	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SFR_RS28830	COG0110	maltose O-acetyltransferase activity
SFR_RS28840	COG1832	CoA-binding protein
SFR_RS28845	COG1739	Uncharacterized protein family UPF0029
SFR_RS28865	COG1595	DNA-templated transcription, initiation
SFR_RS28880	COG0420	3'-5' exonuclease activity
SFR_RS28885	COG0419	ATPase involved in DNA repair
SFR_RS28890	COG1522	sequence-specific DNA binding
SFR_RS28900	COG1028	Short-chain dehydrogenase reductase Sdr
SFR_RS28915	COG0626	cystathionine gamma-synthase activity
SFR_RS28940	COG2188	Transcriptional regulator
SFR_RS28945	COG1940	carbohydrate kinase activity
SFR_RS28960	COG3663	DNA glycosylase
SFR_RS28965	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SFR_RS28985	COG0456	acetyltransferase
SFR_RS28990	COG0488	(ABC) transporter
SFR_RS28995	COG0488	(ABC) transporter
SFR_RS29005	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SFR_RS29010	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SFR_RS29015	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SFR_RS29040	COG0791	NLP P60 protein
SFR_RS29045	COG0740	serine-type endopeptidase activity
SFR_RS29055	COG0831	urea catabolic process
SFR_RS29060	COG0832	Belongs to the urease beta subunit family
SFR_RS29065	COG0804	urea catabolic process
SFR_RS29075	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SFR_RS29080	COG0829	nickel cation binding
SFR_RS29085	COG4552	Acetyltransferase involved in intracellular survival and related
SFR_RS29090	COG0204	Acyl-transferase
SFR_RS29135	COG2175	clavaminate synthase activity
SFR_RS29145	COG0435	Glutathione S-transferase
SFR_RS29150	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SFR_RS29150	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
SFR_RS29160	COG2208	phosphoserine phosphatase activity
SFR_RS29160	COG2770	Histidine kinase
SFR_RS29170	COG0205	6-phosphofructokinase activity
SFR_RS29175	COG3442	glutamine amidotransferase
SFR_RS29185	COG0242	peptide deformylase activity
SFR_RS29195	COG1960	acyl-CoA dehydrogenase activity
SFR_RS29215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SFR_RS29240	COG1175	transmembrane transport
SFR_RS29245	COG0395	ABC-type sugar transport system, permease component
SFR_RS29250	COG2723	6-phospho-beta-galactosidase activity
SFR_RS29255	COG0501	Belongs to the peptidase M48B family
SFR_RS29300	COG4251	negative regulation of phosphorylation
SFR_RS29325	COG0656	L-ascorbic acid biosynthetic process
SFR_RS29335	COG1595	DNA-templated transcription, initiation
SFR_RS29345	COG1132	(ABC) transporter
SFR_RS29370	COG0697	spore germination
SFR_RS29375	COG0546	phosphoglycolate phosphatase activity
SFR_RS29380	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SFR_RS29390	COG2313	pseudouridylate synthase activity
SFR_RS29395	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
SFR_RS29425	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SFR_RS29430	COG3279	Response regulator of the LytR AlgR family
SFR_RS29440	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SFR_RS29445	COG3275	phosphorelay sensor kinase activity
SFR_RS29510	COG0583	DNA-binding transcription factor activity
SFR_RS29520	COG1053	succinate dehydrogenase
SFR_RS29525	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SFR_RS29530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SFR_RS29540	COG3360	Dodecin
SFR_RS29545	COG2182	Extracellular solute-binding protein
SFR_RS29550	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
SFR_RS29555	COG0121	glutamine amidotransferase
SFR_RS29560	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SFR_RS29580	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SFR_RS29585	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SFR_RS29605	COG2837	iron assimilation
SFR_RS29615	COG1796	DNA polymerase
SFR_RS29615	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
SFR_RS29620	COG0142	geranyltranstransferase activity
SFR_RS29650	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
SFR_RS29675	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SFR_RS29685	COG0254	rRNA binding
SFR_RS29690	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SFR_RS29695	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SFR_RS29700	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SFR_RS29730	COG0477	Major facilitator Superfamily
SFR_RS29760	COG3119	arylsulfatase activity
SFR_RS29775	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
SFR_RS29780	COG4948	Mandelate Racemase Muconate Lactonizing
SFR_RS29850	COG0464	growth
SFR_RS29870	COG3655	Transcriptional regulator
SFR_RS29880	COG4257	antibiotic catabolic process
SFR_RS29890	COG0803	Belongs to the bacterial solute-binding protein 9 family
SFR_RS29900	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SFR_RS29905	COG1121	(ABC) transporter
SFR_RS29910	COG4608	Belongs to the ABC transporter superfamily
SFR_RS29915	COG0444	Belongs to the ABC transporter superfamily
SFR_RS29920	COG0601	transmembrane transport
SFR_RS29925	COG0747	negative chemotaxis
SFR_RS29935	COG3458	cephalosporin-C deacetylase activity
SFR_RS29945	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SFR_RS29955	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
SFR_RS29960	COG0363	glucosamine-6-phosphate deaminase activity
SFR_RS29965	COG0590	tRNA wobble adenosine to inosine editing
SFR_RS29970	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SFR_RS30000	COG2201	protein-glutamate methylesterase activity
SFR_RS30005	COG0300	oxidoreductase activity
SFR_RS30015	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SFR_RS30050	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
SFR_RS30055	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
SFR_RS30060	COG1984	allophanate hydrolase subunit 2
SFR_RS30090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SFR_RS30100	COG1120	ATPase activity
SFR_RS30125	COG1132	(ABC) transporter
SFR_RS30130	COG1132	(ABC) transporter
SFR_RS30135	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SFR_RS30145	COG0110	maltose O-acetyltransferase activity
SFR_RS30160	COG0242	peptide deformylase activity
SFR_RS30185	COG1414	Transcriptional regulator
SFR_RS30190	COG3971	2-oxopent-4-enoate hydratase activity
SFR_RS30200	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SFR_RS30220	COG1349	DNA-binding transcription factor activity
SFR_RS30235	COG3395	kinase activity
SFR_RS30240	COG0235	Class ii aldolase
SFR_RS30270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SFR_RS30280	COG4608	Belongs to the ABC transporter superfamily
SFR_RS30285	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SFR_RS30300	COG1028	Short-chain dehydrogenase reductase Sdr
SFR_RS30315	COG2124	cytochrome p450
SFR_RS30320	COG1174	glycine betaine transport
SFR_RS30325	COG1174	glycine betaine transport
SFR_RS30335	COG0517	IMP dehydrogenase activity
SFR_RS30335	COG1125	glycine betaine transport
SFR_RS30360	COG1960	acyl-CoA dehydrogenase activity
SFR_RS30365	COG1960	acyl-CoA dehydrogenase activity
SFR_RS30375	COG0601	transmembrane transport
SFR_RS30380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SFR_RS30385	COG0444	Belongs to the ABC transporter superfamily
SFR_RS30390	COG1124	(ABC) transporter
SFR_RS30400	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
SFR_RS30405	COG2318	DinB family
SFR_RS30430	COG0277	FAD linked oxidase domain protein
SFR_RS30435	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SFR_RS30445	COG2814	Major facilitator Superfamily
SFR_RS30495	COG1028	Short-chain dehydrogenase reductase Sdr
SFR_RS30505	COG0142	geranyltranstransferase activity
SFR_RS30545	COG0604	alcohol dehydrogenase
SFR_RS30545	COG3321	synthase
SFR_RS30575	COG0604	alcohol dehydrogenase
SFR_RS30575	COG3321	synthase
SFR_RS30595	COG2124	cytochrome p450
SFR_RS30600	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SFR_RS30635	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SFR_RS30675	COG3483	tryptophan 2,3-dioxygenase activity
SFR_RS30680	COG1028	Short-chain dehydrogenase reductase Sdr
SFR_RS30685	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SFR_RS30690	COG2151	metal-sulfur cluster biosynthetic enzyme
SFR_RS30695	COG3396	Phenylacetate-CoA oxygenase
SFR_RS30705	COG3396	Phenylacetate-CoA oxygenase
SFR_RS30720	COG0604	alcohol dehydrogenase
SFR_RS30730	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SFR_RS30780	COG0515	serine threonine protein kinase
SFR_RS30810	COG1404	Belongs to the peptidase S8 family
SFR_RS30855	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SFR_RS30865	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SFR_RS30865	COG1028	Short-chain dehydrogenase reductase Sdr
SFR_RS30865	COG0318	PFAM AMP-dependent synthetase and ligase
SFR_RS30865	COG0300	oxidoreductase activity
SFR_RS30865	COG3321	synthase
SFR_RS30870	COG3321	synthase
SFR_RS30870	COG1028	Short-chain dehydrogenase reductase Sdr
SFR_RS30870	COG0604	alcohol dehydrogenase
SFR_RS30890	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SFR_RS30890	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SFR_RS30890	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SFR_RS30890	COG3321	synthase
SFR_RS30890	COG1028	Short-chain dehydrogenase reductase Sdr
SFR_RS30895	COG3321	synthase
SFR_RS30895	COG0604	alcohol dehydrogenase
SFR_RS30900	COG4221	oxidoreductase activity
SFR_RS30900	COG3321	synthase
SFR_RS30900	COG0300	oxidoreductase activity
SFR_RS30900	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SFR_RS30910	COG4335	DNA alkylation repair
SFR_RS30940	COG0477	Major facilitator Superfamily
SFR_RS30970	COG3246	L-lysine catabolic process to acetate
SFR_RS30975	COG1250	3-hydroxyacyl-CoA dehydrogenase
SFR_RS31150	COG2801	Transposase and inactivated derivatives
SFR_RS31200	COG3386	PFAM SMP-30 Gluconolaconase
SFR_RS31210	COG4948	Mandelate Racemase Muconate Lactonizing
SFR_RS31230	COG1063	alcohol dehydrogenase
SFR_RS31250	COG1879	ABC-type sugar transport system periplasmic component