locus-tag	class	description
KNZ81_RS00070	COG2205	protein histidine kinase activity
KNZ81_RS00075	COG0745	RESPONSE REGULATOR receiver
KNZ81_RS00115	COG0577	efflux transmembrane transporter activity
KNZ81_RS00120	COG1136	(ABC) transporter
KNZ81_RS00135	COG0745	RESPONSE REGULATOR receiver
KNZ81_RS00140	COG5002	protein histidine kinase activity
KNZ81_RS00155	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KNZ81_RS00160	COG0066	3-isopropylmalate dehydratase activity
KNZ81_RS00165	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KNZ81_RS00170	COG1028	Short-chain dehydrogenase reductase Sdr
KNZ81_RS00175	COG1028	Short-chain dehydrogenase reductase Sdr
KNZ81_RS00215	COG4106	trans-aconitate 2-methyltransferase activity
KNZ81_RS00275	COG2814	Major facilitator Superfamily
KNZ81_RS00310	COG1012	belongs to the aldehyde dehydrogenase family
KNZ81_RS00320	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KNZ81_RS00340	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KNZ81_RS00350	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KNZ81_RS00355	COG3629	intracellular signal transduction
KNZ81_RS00365	COG0477	Major facilitator Superfamily
KNZ81_RS00375	COG0604	alcohol dehydrogenase
KNZ81_RS00375	COG3321	synthase
KNZ81_RS00435	COG3629	intracellular signal transduction
KNZ81_RS00470	COG1028	Short-chain dehydrogenase reductase Sdr
KNZ81_RS00490	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KNZ81_RS00545	COG1472	Belongs to the glycosyl hydrolase 3 family
KNZ81_RS00550	COG1874	Beta-galactosidase
KNZ81_RS00555	COG1609	Transcriptional regulator
KNZ81_RS00560	COG0395	ABC-type sugar transport system, permease component
KNZ81_RS00565	COG1175	transmembrane transport
KNZ81_RS00585	COG1028	Short-chain dehydrogenase reductase Sdr
KNZ81_RS00590	COG0477	Major facilitator Superfamily
KNZ81_RS00615	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KNZ81_RS00620	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
KNZ81_RS00625	COG2080	2 iron, 2 sulfur cluster binding
KNZ81_RS00635	COG2197	response regulator
KNZ81_RS00640	COG4585	Histidine kinase
KNZ81_RS00645	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
KNZ81_RS00650	COG1053	succinate dehydrogenase
KNZ81_RS00655	COG1028	Short-chain dehydrogenase reductase Sdr
KNZ81_RS00665	COG0477	Major facilitator Superfamily
KNZ81_RS00720	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KNZ81_RS00720	COG0446	pyridine nucleotide-disulphide oxidoreductase
KNZ81_RS00765	COG4608	Belongs to the ABC transporter superfamily
KNZ81_RS00770	COG0444	Belongs to the ABC transporter superfamily
KNZ81_RS00775	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KNZ81_RS00780	COG0601	transmembrane transport
KNZ81_RS00795	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KNZ81_RS00830	COG1793	dna ligase
KNZ81_RS00845	COG0277	FAD linked oxidase domain protein
KNZ81_RS00890	COG0318	PFAM AMP-dependent synthetase and ligase
KNZ81_RS00895	COG0589	response to stress
KNZ81_RS00900	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KNZ81_RS00905	COG2813	Specifically methylates the guanine in position
KNZ81_RS00915	COG2356	endonuclease I
KNZ81_RS00965	COG2084	Dehydrogenase
KNZ81_RS01000	COG1007	ATP synthesis coupled electron transport
KNZ81_RS01005	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KNZ81_RS01010	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KNZ81_RS01015	COG0713	ATP synthesis coupled electron transport
KNZ81_RS01025	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
KNZ81_RS01035	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KNZ81_RS01045	COG5297	Belongs to the glycosyl hydrolase family 6
KNZ81_RS01045	COG4733	cellulase activity
KNZ81_RS01055	COG0446	pyridine nucleotide-disulphide oxidoreductase
KNZ81_RS01055	COG1902	pentaerythritol trinitrate reductase activity
KNZ81_RS01065	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KNZ81_RS01095	COG0475	glutathione-regulated potassium exporter activity
KNZ81_RS01115	COG2197	response regulator
KNZ81_RS01125	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KNZ81_RS01135	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KNZ81_RS01145	COG3559	Exporter of polyketide antibiotics
KNZ81_RS01150	COG1131	(ABC) transporter
KNZ81_RS01155	COG1309	transcriptional regulator
KNZ81_RS01170	COG0477	Major facilitator Superfamily
KNZ81_RS01185	COG0328	RNA-DNA hybrid ribonuclease activity
KNZ81_RS01225	COG1595	DNA-templated transcription, initiation
KNZ81_RS01250	COG0667	Aldo Keto reductase
KNZ81_RS01265	COG0300	oxidoreductase activity
KNZ81_RS01280	COG1028	Short-chain dehydrogenase reductase Sdr
KNZ81_RS01285	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KNZ81_RS01300	COG1131	(ABC) transporter
KNZ81_RS01320	COG0326	Molecular chaperone. Has ATPase activity
KNZ81_RS01345	COG0346	lactoylglutathione lyase activity
KNZ81_RS01350	COG0640	Transcriptional regulator
KNZ81_RS01365	COG1120	ATPase activity
KNZ81_RS01390	COG1250	3-hydroxyacyl-CoA dehydrogenase
KNZ81_RS01395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KNZ81_RS01405	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KNZ81_RS01420	COG1349	DNA-binding transcription factor activity
KNZ81_RS01430	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KNZ81_RS01430	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KNZ81_RS01430	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
KNZ81_RS01435	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KNZ81_RS01435	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KNZ81_RS01440	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KNZ81_RS01465	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KNZ81_RS01485	COG0275	rRNA processing
KNZ81_RS01495	COG1695	Transcriptional regulator
KNZ81_RS01525	COG1028	Short-chain dehydrogenase reductase Sdr
KNZ81_RS01540	COG0513	Belongs to the DEAD box helicase family
KNZ81_RS01550	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KNZ81_RS01585	COG1349	DNA-binding transcription factor activity
KNZ81_RS01605	COG1940	carbohydrate kinase activity
KNZ81_RS01615	COG2223	nitrite transmembrane transporter activity
KNZ81_RS01645	COG1609	Transcriptional regulator
KNZ81_RS01655	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KNZ81_RS01700	COG0584	glycerophosphoryl diester phosphodiesterase
KNZ81_RS01715	COG1846	Transcriptional regulator
KNZ81_RS01735	COG0671	phosphoesterase, PA-phosphatase related
KNZ81_RS01780	COG0577	efflux transmembrane transporter activity
KNZ81_RS01780	COG1136	(ABC) transporter
KNZ81_RS01805	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KNZ81_RS01830	COG0165	Argininosuccinate lyase
KNZ81_RS01840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KNZ81_RS01845	COG1834	amidinotransferase
KNZ81_RS01855	COG1024	Enoyl-CoA hydratase
KNZ81_RS01860	COG1024	Enoyl-CoA hydratase
KNZ81_RS01865	COG3424	synthase
KNZ81_RS01870	COG2175	clavaminate synthase activity
KNZ81_RS01895	COG0604	alcohol dehydrogenase
KNZ81_RS01895	COG3321	synthase
KNZ81_RS01940	COG2233	PERMEase
KNZ81_RS01945	COG0640	Transcriptional regulator
KNZ81_RS01950	COG1902	pentaerythritol trinitrate reductase activity
KNZ81_RS01980	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KNZ81_RS01995	COG2706	6-phosphogluconolactonase activity
KNZ81_RS02000	COG2801	Transposase and inactivated derivatives
KNZ81_RS02000	COG3415	Transposase
KNZ81_RS02025	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KNZ81_RS02070	COG1472	Belongs to the glycosyl hydrolase 3 family
KNZ81_RS02075	COG0395	ABC-type sugar transport system, permease component
KNZ81_RS02080	COG1175	transmembrane transport
KNZ81_RS02135	COG0432	Pfam Uncharacterised protein family UPF0047
KNZ81_RS02150	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KNZ81_RS02155	COG1132	(ABC) transporter
KNZ81_RS02180	COG1132	(ABC) transporter
KNZ81_RS02185	COG1132	(ABC) transporter
KNZ81_RS02200	COG1946	Acyl-CoA thioesterase
KNZ81_RS02215	COG2018	Roadblock/LC7 domain
KNZ81_RS02260	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KNZ81_RS02295	COG2124	cytochrome p450
KNZ81_RS02300	COG2130	NADP-dependent
KNZ81_RS02305	COG1233	COG1233 Phytoene dehydrogenase and related
KNZ81_RS02375	COG0477	Major facilitator Superfamily
KNZ81_RS02385	COG0583	DNA-binding transcription factor activity
KNZ81_RS02390	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KNZ81_RS02395	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KNZ81_RS02400	COG1250	3-hydroxyacyl-CoA dehydrogenase
KNZ81_RS02405	COG1960	acyl-CoA dehydrogenase activity
KNZ81_RS02410	COG2391	methyltransferase activity
KNZ81_RS02450	COG0740	serine-type endopeptidase activity
KNZ81_RS02455	COG0740	serine-type endopeptidase activity
KNZ81_RS02480	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KNZ81_RS02490	COG0798	PFAM Bile acid sodium symporter
KNZ81_RS02495	COG2072	flavoprotein involved in K transport
KNZ81_RS02500	COG0659	secondary active sulfate transmembrane transporter activity
KNZ81_RS02505	COG0789	Transcriptional regulator
KNZ81_RS02510	COG0640	Transcriptional regulator
KNZ81_RS02540	COG3959	Transketolase, thiamine diphosphate binding domain
KNZ81_RS02545	COG3958	Transketolase
KNZ81_RS02605	COG2755	lipolytic protein G-D-S-L family
KNZ81_RS02610	COG2365	Tyrosine phosphatase family
KNZ81_RS02640	COG1657	PFAM Prenyltransferase squalene oxidase
KNZ81_RS02650	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KNZ81_RS02660	COG1562	ergosterol biosynthetic process
KNZ81_RS02665	COG1388	LysM domain
KNZ81_RS02665	COG1134	teichoic acid transport
KNZ81_RS02690	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KNZ81_RS02705	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
KNZ81_RS02720	COG1024	Enoyl-CoA hydratase
KNZ81_RS02750	COG1802	Transcriptional regulator
KNZ81_RS02755	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KNZ81_RS02760	COG0402	S-adenosylhomocysteine deaminase activity
KNZ81_RS02785	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KNZ81_RS02790	COG0789	Transcriptional regulator
KNZ81_RS02795	COG1024	Enoyl-CoA hydratase
KNZ81_RS02795	COG1250	3-hydroxyacyl-CoA dehydrogenase
KNZ81_RS02800	COG0183	Belongs to the thiolase family
KNZ81_RS02810	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KNZ81_RS02815	COG1683	Conserved Protein
KNZ81_RS02820	COG1515	deoxyribonuclease V activity
KNZ81_RS02840	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KNZ81_RS02850	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KNZ81_RS02850	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KNZ81_RS02860	COG0488	(ABC) transporter
KNZ81_RS02880	COG2197	response regulator
KNZ81_RS02895	COG0438	transferase activity, transferring glycosyl groups
KNZ81_RS02925	COG0254	rRNA binding
KNZ81_RS02935	COG1793	dna ligase
KNZ81_RS02940	COG1024	Enoyl-CoA hydratase
KNZ81_RS02980	COG0789	Transcriptional regulator
KNZ81_RS03005	COG2319	Wd-40 repeat
KNZ81_RS03005	COG4249	Peptidase C14 caspase catalytic subunit p20
KNZ81_RS03030	COG2274	protein secretion by the type I secretion system
KNZ81_RS03035	COG2274	protein secretion by the type I secretion system
KNZ81_RS03045	COG2259	Doxx family
KNZ81_RS03055	COG1869	D-ribose catabolic process
KNZ81_RS03060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KNZ81_RS03065	COG1172	Belongs to the binding-protein-dependent transport system permease family
KNZ81_RS03070	COG1129	ABC transporter
KNZ81_RS03075	COG1609	Transcriptional regulator
KNZ81_RS03095	COG1295	ribonuclease BN
KNZ81_RS03160	COG0673	inositol 2-dehydrogenase activity
KNZ81_RS03170	COG1172	Belongs to the binding-protein-dependent transport system permease family
KNZ81_RS03175	COG1129	ABC transporter
KNZ81_RS03180	COG1940	carbohydrate kinase activity
KNZ81_RS03185	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KNZ81_RS03200	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KNZ81_RS03210	COG0583	DNA-binding transcription factor activity
KNZ81_RS03215	COG1115	amino acid carrier protein
KNZ81_RS03240	COG2154	pterin-4-alpha-carbinolamine dehydratase
KNZ81_RS03315	COG0693	protein deglycase activity
KNZ81_RS03325	COG1597	lipid kinase activity
KNZ81_RS03330	COG4106	trans-aconitate 2-methyltransferase activity
KNZ81_RS03345	COG3226	Transcriptional regulator
KNZ81_RS03360	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KNZ81_RS03375	COG1309	transcriptional regulator
KNZ81_RS03390	COG1619	proteins homologs of microcin C7 resistance protein MccF
KNZ81_RS03400	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KNZ81_RS03475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KNZ81_RS03480	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KNZ81_RS03485	COG1120	ATPase activity
KNZ81_RS03490	COG1250	3-hydroxyacyl-CoA dehydrogenase
KNZ81_RS03500	COG0604	alcohol dehydrogenase
KNZ81_RS03505	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KNZ81_RS03505	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KNZ81_RS03510	COG2301	Belongs to the HpcH HpaI aldolase family
KNZ81_RS03525	COG0688	phosphatidylethanolamine metabolic process
KNZ81_RS03540	COG1929	Belongs to the glycerate kinase type-1 family
KNZ81_RS03545	COG0488	(ABC) transporter
KNZ81_RS03555	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KNZ81_RS03560	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
KNZ81_RS03585	COG0159	tryptophan synthase activity
KNZ81_RS03610	COG0483	inositol monophosphate 1-phosphatase activity
KNZ81_RS03620	COG0095	Lipoate-protein ligase
KNZ81_RS03640	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KNZ81_RS03665	COG0405	Gamma-glutamyltransferase
KNZ81_RS03690	COG0765	amino acid transport
KNZ81_RS03695	COG0765	amino acid transport
KNZ81_RS03700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KNZ81_RS03705	COG1126	abc transporter atp-binding protein
KNZ81_RS03730	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KNZ81_RS03745	COG2133	pyrroloquinoline quinone binding
KNZ81_RS03745	COG5183	chlorophyll binding
KNZ81_RS03750	COG1132	(ABC) transporter
KNZ81_RS03755	COG1132	(ABC) transporter
KNZ81_RS03780	COG2197	response regulator
KNZ81_RS03790	COG0464	growth
KNZ81_RS03875	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KNZ81_RS03885	COG1940	carbohydrate kinase activity
KNZ81_RS03895	COG1172	Belongs to the binding-protein-dependent transport system permease family
KNZ81_RS03905	COG2188	Transcriptional regulator
KNZ81_RS03910	COG0673	inositol 2-dehydrogenase activity
KNZ81_RS03920	COG2197	response regulator
KNZ81_RS03925	COG4585	Histidine kinase
KNZ81_RS03940	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KNZ81_RS03945	COG1414	Transcriptional regulator
KNZ81_RS03960	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KNZ81_RS03965	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
KNZ81_RS03970	COG2080	2 iron, 2 sulfur cluster binding
KNZ81_RS03975	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KNZ81_RS03990	COG4941	Belongs to the sigma-70 factor family
KNZ81_RS03995	COG3795	YCII-related domain
KNZ81_RS04000	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KNZ81_RS04005	COG1621	beta-fructofuranosidase activity
KNZ81_RS04010	COG1609	Transcriptional regulator
KNZ81_RS04025	COG1609	Transcriptional regulator
KNZ81_RS04075	COG2233	PERMEase
KNZ81_RS04090	COG2351	hydroxyisourate hydrolase activity
KNZ81_RS04110	COG3622	Belongs to the hyi family
KNZ81_RS04115	COG2084	Dehydrogenase
KNZ81_RS04120	COG0753	catalase activity
KNZ81_RS04130	COG3960	tartronate-semialdehyde synthase activity
KNZ81_RS04140	COG0318	PFAM AMP-dependent synthetase and ligase
KNZ81_RS04145	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KNZ81_RS04150	COG2197	response regulator
KNZ81_RS04190	COG1073	alpha beta
KNZ81_RS04215	COG2252	PERMEase
KNZ81_RS04220	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KNZ81_RS04235	COG3835	regulator
KNZ81_RS04245	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KNZ81_RS04255	COG1802	Transcriptional regulator
KNZ81_RS04275	COG0028	Belongs to the TPP enzyme family
KNZ81_RS04295	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KNZ81_RS04300	COG1162	GTPase activity
KNZ81_RS04310	COG2365	Tyrosine phosphatase family
KNZ81_RS04345	COG1595	DNA-templated transcription, initiation
KNZ81_RS04365	COG0702	epimerase
KNZ81_RS04370	COG1846	Transcriptional regulator
KNZ81_RS04375	COG2409	Drug exporters of the RND superfamily
KNZ81_RS04385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KNZ81_RS04390	COG1120	ATPase activity
KNZ81_RS04400	COG2255	four-way junction helicase activity
KNZ81_RS04425	COG2040	homocysteine
KNZ81_RS04445	COG1960	acyl-CoA dehydrogenase activity
KNZ81_RS04450	COG0604	alcohol dehydrogenase
KNZ81_RS04475	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KNZ81_RS04485	COG0175	sulfate reduction
KNZ81_RS04490	COG0529	Catalyzes the synthesis of activated sulfate
KNZ81_RS04515	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
KNZ81_RS04520	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KNZ81_RS04535	COG0386	Belongs to the glutathione peroxidase family
KNZ81_RS04570	COG5002	protein histidine kinase activity
KNZ81_RS04570	COG2176	DNA-directed DNA polymerase activity
KNZ81_RS04635	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KNZ81_RS04640	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KNZ81_RS04680	COG0726	polysaccharide deacetylase
KNZ81_RS04690	COG3220	belongs to the UPF0276 family
KNZ81_RS04700	COG3253	May function as heme-dependent peroxidase
KNZ81_RS04705	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KNZ81_RS04715	COG0446	pyridine nucleotide-disulphide oxidoreductase
KNZ81_RS04720	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KNZ81_RS04740	COG0183	Belongs to the thiolase family
KNZ81_RS04745	COG1024	Enoyl-CoA hydratase
KNZ81_RS04745	COG1250	3-hydroxyacyl-CoA dehydrogenase
KNZ81_RS04765	COG0531	amino acid
KNZ81_RS04770	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KNZ81_RS04775	COG4214	carbohydrate transport
KNZ81_RS04785	COG4213	ABC transporter substrate-binding protein
KNZ81_RS04795	COG0395	ABC-type sugar transport system, permease component
KNZ81_RS04800	COG1175	transmembrane transport
KNZ81_RS04805	COG1653	transport
KNZ81_RS04810	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KNZ81_RS04845	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KNZ81_RS04885	COG1320	monovalent cation:proton antiporter activity
KNZ81_RS04900	COG0651	ATP synthesis coupled electron transport
KNZ81_RS04910	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KNZ81_RS04910	COG2111	Na H antiporter
KNZ81_RS04920	COG2124	cytochrome p450
KNZ81_RS04950	COG0531	amino acid
KNZ81_RS04955	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KNZ81_RS04975	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KNZ81_RS05010	COG1799	cell septum assembly
KNZ81_RS05020	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
KNZ81_RS05035	COG1556	Lactate utilization protein
KNZ81_RS05040	COG1139	Iron-sulfur cluster binding protein
KNZ81_RS05045	COG0247	lactate metabolic process
KNZ81_RS05050	COG1620	l-lactate permease
KNZ81_RS05095	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KNZ81_RS05110	COG1120	ATPase activity
KNZ81_RS05115	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KNZ81_RS05120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KNZ81_RS05130	COG1733	regulation of RNA biosynthetic process
KNZ81_RS05180	COG3540	Alkaline phosphatase
KNZ81_RS05190	COG2050	protein possibly involved in aromatic compounds catabolism
KNZ81_RS05205	COG0789	Transcriptional regulator
KNZ81_RS05210	COG0640	Transcriptional regulator
KNZ81_RS05230	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KNZ81_RS05270	COG3226	Transcriptional regulator
KNZ81_RS05275	COG0738	Major facilitator superfamily
KNZ81_RS05280	COG0252	asparaginase activity
KNZ81_RS05325	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KNZ81_RS05335	COG0473	3-isopropylmalate dehydrogenase activity
KNZ81_RS05350	COG0656	L-ascorbic acid biosynthetic process
KNZ81_RS05385	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KNZ81_RS05410	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KNZ81_RS05420	COG1127	ABC transporter
KNZ81_RS05515	COG0395	ABC-type sugar transport system, permease component
KNZ81_RS05520	COG1063	alcohol dehydrogenase
KNZ81_RS05575	COG1201	RNA secondary structure unwinding
KNZ81_RS05600	COG2732	(Barnase) inhibitor
KNZ81_RS05620	COG2188	Transcriptional regulator
KNZ81_RS05630	COG1674	ftsk spoiiie
KNZ81_RS05645	COG0582	viral genome integration into host DNA
KNZ81_RS05665	COG0438	transferase activity, transferring glycosyl groups
KNZ81_RS05675	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KNZ81_RS05680	COG0531	amino acid
KNZ81_RS05685	COG0569	domain protein
KNZ81_RS05715	COG1136	(ABC) transporter
KNZ81_RS05735	COG0756	dUTP diphosphatase activity
KNZ81_RS05760	COG2205	protein histidine kinase activity
KNZ81_RS05765	COG0745	RESPONSE REGULATOR receiver
KNZ81_RS05775	COG0483	inositol monophosphate 1-phosphatase activity
KNZ81_RS05780	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KNZ81_RS05830	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KNZ81_RS05835	COG1802	Transcriptional regulator
KNZ81_RS05850	COG0612	Peptidase, M16
KNZ81_RS05855	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KNZ81_RS05870	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KNZ81_RS05885	COG1309	transcriptional regulator
KNZ81_RS05890	COG0187	DNA topoisomerase II activity
KNZ81_RS05905	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KNZ81_RS05910	COG1802	Transcriptional regulator
KNZ81_RS05950	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KNZ81_RS05965	COG0588	phosphoglycerate mutase activity
KNZ81_RS05990	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KNZ81_RS05995	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KNZ81_RS06000	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KNZ81_RS06040	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KNZ81_RS06050	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KNZ81_RS06055	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KNZ81_RS06065	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KNZ81_RS06085	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KNZ81_RS06095	COG2205	protein histidine kinase activity
KNZ81_RS06100	COG0745	RESPONSE REGULATOR receiver
KNZ81_RS06105	COG1126	abc transporter atp-binding protein
KNZ81_RS06110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KNZ81_RS06115	COG0765	amino acid transport
KNZ81_RS06120	COG0765	amino acid transport
KNZ81_RS06125	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KNZ81_RS06135	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KNZ81_RS06140	COG2137	regulation of response to DNA damage stimulus
KNZ81_RS06145	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KNZ81_RS06165	COG0628	permease
KNZ81_RS06190	COG1201	RNA secondary structure unwinding
KNZ81_RS06195	COG0596	Alpha beta hydrolase
KNZ81_RS06215	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KNZ81_RS06225	COG0783	Belongs to the Dps family
KNZ81_RS06230	COG1396	sequence-specific DNA binding
KNZ81_RS06235	COG1058	Belongs to the CinA family
KNZ81_RS06235	COG1546	Belongs to the CinA family
KNZ81_RS06245	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KNZ81_RS06255	COG1674	ftsk spoiiie
KNZ81_RS06265	COG2205	protein histidine kinase activity
KNZ81_RS06265	COG4999	Histidine kinase
KNZ81_RS06265	COG3850	Histidine kinase
KNZ81_RS06265	COG3437	response regulator, receiver
KNZ81_RS06270	COG2770	Histidine kinase
KNZ81_RS06270	COG2208	phosphoserine phosphatase activity
KNZ81_RS06280	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KNZ81_RS06300	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KNZ81_RS06305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KNZ81_RS06310	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
KNZ81_RS06330	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KNZ81_RS06335	COG0612	Peptidase, M16
KNZ81_RS06340	COG1185	polyribonucleotide nucleotidyltransferase activity
KNZ81_RS06345	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KNZ81_RS06355	COG0455	bacterial-type flagellum organization
KNZ81_RS06360	COG4166	transmembrane transport
KNZ81_RS06365	COG0601	transmembrane transport
KNZ81_RS06370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KNZ81_RS06375	COG0444	Belongs to the ABC transporter superfamily
KNZ81_RS06380	COG4608	Belongs to the ABC transporter superfamily
KNZ81_RS06385	COG1357	PFAM Pentapeptide repeats (8 copies)
KNZ81_RS06400	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KNZ81_RS06405	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KNZ81_RS06415	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KNZ81_RS06430	COG0779	Required for maturation of 30S ribosomal subunits
KNZ81_RS06450	COG0442	prolyl-tRNA aminoacylation
KNZ81_RS06470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KNZ81_RS06475	COG0601	transmembrane transport
KNZ81_RS06480	COG0747	negative chemotaxis
KNZ81_RS06495	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KNZ81_RS06500	COG0750	zinc metalloprotease
KNZ81_RS06505	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KNZ81_RS06510	COG1940	carbohydrate kinase activity
KNZ81_RS06515	COG1012	belongs to the aldehyde dehydrogenase family
KNZ81_RS06520	COG2508	Transcriptional regulator
KNZ81_RS06550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KNZ81_RS06555	COG1177	transmembrane transport
KNZ81_RS06560	COG1176	ABC-type spermidine putrescine transport system, permease component I
KNZ81_RS06565	COG3842	ATPase activity
KNZ81_RS06575	COG1012	belongs to the aldehyde dehydrogenase family
KNZ81_RS06590	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KNZ81_RS06595	COG0584	glycerophosphoryl diester phosphodiesterase
KNZ81_RS06610	COG1012	belongs to the aldehyde dehydrogenase family
KNZ81_RS06620	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KNZ81_RS06645	COG3842	ATPase activity
KNZ81_RS06650	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KNZ81_RS06660	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KNZ81_RS06670	COG0233	cytoplasmic translational termination
KNZ81_RS06675	COG0528	UMP kinase activity
KNZ81_RS06680	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KNZ81_RS06685	COG0052	Belongs to the universal ribosomal protein uS2 family
KNZ81_RS06690	COG1388	LysM domain
KNZ81_RS06690	COG4942	peptidase
KNZ81_RS06700	COG1191	sigma factor activity
KNZ81_RS06790	COG0629	single-stranded DNA binding
KNZ81_RS06980	COG0792	nuclease activity
KNZ81_RS06995	COG0681	Belongs to the peptidase S26 family
KNZ81_RS07000	COG0681	Belongs to the peptidase S26 family
KNZ81_RS07010	COG0681	Belongs to the peptidase S26 family
KNZ81_RS07015	COG0335	large ribosomal subunit rRNA binding
KNZ81_RS07020	COG0336	Belongs to the RNA methyltransferase TrmD family
KNZ81_RS07025	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KNZ81_RS07030	COG1837	Belongs to the UPF0109 family
KNZ81_RS07035	COG0228	four-way junction DNA binding
KNZ81_RS07050	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KNZ81_RS07060	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
KNZ81_RS07090	COG0477	Major facilitator Superfamily
KNZ81_RS07095	COG1196	nuclear chromosome segregation
KNZ81_RS07105	COG1254	Belongs to the acylphosphatase family
KNZ81_RS07110	COG2340	Cysteine-rich secretory protein family
KNZ81_RS07115	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KNZ81_RS07120	COG0571	ribonuclease III activity
KNZ81_RS07125	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KNZ81_RS07140	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KNZ81_RS07145	COG0742	ribosomal rna small subunit methyltransferase
KNZ81_RS07155	COG1461	Dihydroxyacetone kinase
KNZ81_RS07160	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KNZ81_RS07165	COG0351	phosphomethylpyrimidine kinase
KNZ81_RS07185	COG1181	Belongs to the D-alanine--D-alanine ligase family
KNZ81_RS07190	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KNZ81_RS07200	COG1920	GTP binding
KNZ81_RS07210	COG0776	regulation of translation
KNZ81_RS07220	COG0066	3-isopropylmalate dehydratase activity
KNZ81_RS07225	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KNZ81_RS07230	COG1414	Transcriptional regulator
KNZ81_RS07240	COG0789	Transcriptional regulator
KNZ81_RS07275	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KNZ81_RS07280	COG0179	Fumarylacetoacetate (FAA) hydrolase
KNZ81_RS07295	COG2018	Roadblock/LC7 domain
KNZ81_RS07315	COG2018	Roadblock/LC7 domain
KNZ81_RS07335	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KNZ81_RS07345	COG2353	YceI-like domain
KNZ81_RS07365	COG0789	Transcriptional regulator
KNZ81_RS07405	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KNZ81_RS07410	COG0477	Major facilitator Superfamily
KNZ81_RS07415	COG2957	Belongs to the agmatine deiminase family
KNZ81_RS07420	COG0804	urea catabolic process
KNZ81_RS07425	COG0832	Belongs to the urease beta subunit family
KNZ81_RS07425	COG0831	urea catabolic process
KNZ81_RS07430	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KNZ81_RS07435	COG0473	3-isopropylmalate dehydrogenase activity
KNZ81_RS07450	COG0575	Belongs to the CDS family
KNZ81_RS07465	COG1012	belongs to the aldehyde dehydrogenase family
KNZ81_RS07470	COG0506	proline dehydrogenase activity
KNZ81_RS07475	COG3835	regulator
KNZ81_RS07495	COG2890	protein-(glutamine-N5) methyltransferase activity
KNZ81_RS07505	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KNZ81_RS07510	COG0440	acetolactate synthase activity
KNZ81_RS07530	COG0667	Aldo Keto reductase
KNZ81_RS07535	COG2133	pyrroloquinoline quinone binding
KNZ81_RS07570	COG2409	Drug exporters of the RND superfamily
KNZ81_RS07575	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KNZ81_RS07585	COG0154	amidase activity
KNZ81_RS07590	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KNZ81_RS07600	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KNZ81_RS07610	COG4221	oxidoreductase activity
KNZ81_RS07630	COG0482	sulfurtransferase activity
KNZ81_RS07655	COG2860	membrane
KNZ81_RS07660	COG4608	Belongs to the ABC transporter superfamily
KNZ81_RS07665	COG0444	Belongs to the ABC transporter superfamily
KNZ81_RS07670	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KNZ81_RS07675	COG0601	transmembrane transport
KNZ81_RS07680	COG4166	transmembrane transport
KNZ81_RS07700	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KNZ81_RS07705	COG0509	glycine decarboxylation via glycine cleavage system
KNZ81_RS07710	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KNZ81_RS07715	COG1760	l-serine dehydratase
KNZ81_RS07730	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
KNZ81_RS07735	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
KNZ81_RS07740	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
KNZ81_RS07755	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KNZ81_RS07780	COG2085	NADP oxidoreductase coenzyme F420-dependent
KNZ81_RS07805	COG1376	ErfK ybiS ycfS ynhG family protein
KNZ81_RS07830	COG1132	(ABC) transporter
KNZ81_RS07835	COG1132	(ABC) transporter
KNZ81_RS07845	COG3903	Transcriptional regulator
KNZ81_RS07845	COG3629	intracellular signal transduction
KNZ81_RS07865	COG0366	Alpha amylase catalytic
KNZ81_RS07870	COG0366	Alpha amylase catalytic
KNZ81_RS07875	COG3281	Trehalose synthase
KNZ81_RS07880	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KNZ81_RS07895	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KNZ81_RS07910	COG1301	dicarboxylic acid transport
KNZ81_RS07915	COG3290	protein histidine kinase activity
KNZ81_RS07920	COG4565	transcriptional regulatory protein
KNZ81_RS07925	COG0205	6-phosphofructokinase activity
KNZ81_RS07930	COG0280	phosphate acetyltransferase
KNZ81_RS07930	COG0857	belongs to the CobB CobQ family
KNZ81_RS07935	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KNZ81_RS07975	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KNZ81_RS07975	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KNZ81_RS08005	COG2945	thiolester hydrolase activity
KNZ81_RS08005	COG0596	Alpha beta hydrolase
KNZ81_RS08045	COG1335	isochorismatase
KNZ81_RS08050	COG2205	protein histidine kinase activity
KNZ81_RS08075	COG0183	Belongs to the thiolase family
KNZ81_RS08095	COG1131	(ABC) transporter
KNZ81_RS08130	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
KNZ81_RS08145	COG1250	3-hydroxyacyl-CoA dehydrogenase
KNZ81_RS08160	COG4585	Histidine kinase
KNZ81_RS08165	COG2197	response regulator
KNZ81_RS08185	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KNZ81_RS08190	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KNZ81_RS08195	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KNZ81_RS08200	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KNZ81_RS08205	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KNZ81_RS08210	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KNZ81_RS08215	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KNZ81_RS08230	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KNZ81_RS08235	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KNZ81_RS08245	COG2890	protein-(glutamine-N5) methyltransferase activity
KNZ81_RS08250	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KNZ81_RS08255	COG0254	rRNA binding
KNZ81_RS08260	COG1316	TRANSCRIPTIONal
KNZ81_RS08270	COG0083	homoserine kinase activity
KNZ81_RS08275	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KNZ81_RS08280	COG0460	homoserine dehydrogenase
KNZ81_RS08285	COG0019	diaminopimelate decarboxylase activity
KNZ81_RS08290	COG0018	arginyl-trna synthetase
KNZ81_RS08315	COG1028	Short-chain dehydrogenase reductase Sdr
KNZ81_RS08330	COG1012	belongs to the aldehyde dehydrogenase family
KNZ81_RS08340	COG1191	sigma factor activity
KNZ81_RS08345	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KNZ81_RS08345	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KNZ81_RS08355	COG2267	carboxylic ester hydrolase activity
KNZ81_RS08360	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
KNZ81_RS08375	COG0772	Belongs to the SEDS family
KNZ81_RS08380	COG0768	penicillin binding
KNZ81_RS08450	COG0726	polysaccharide deacetylase
KNZ81_RS08455	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KNZ81_RS08460	COG0477	Major facilitator Superfamily
KNZ81_RS08475	COG1595	DNA-templated transcription, initiation
KNZ81_RS08485	COG1131	(ABC) transporter
KNZ81_RS08505	COG0745	RESPONSE REGULATOR receiver
KNZ81_RS08510	COG2205	protein histidine kinase activity
KNZ81_RS08515	COG0567	Dehydrogenase, E1 component
KNZ81_RS08515	COG0508	dehydrogenase complex catalyzes the overall conversion of
KNZ81_RS08545	COG2255	four-way junction helicase activity
KNZ81_RS08585	COG0604	alcohol dehydrogenase
KNZ81_RS08590	COG0281	malic enzyme
KNZ81_RS08595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KNZ81_RS08605	COG1126	abc transporter atp-binding protein
KNZ81_RS08610	COG4106	trans-aconitate 2-methyltransferase activity
KNZ81_RS08655	COG0142	geranyltranstransferase activity
KNZ81_RS08665	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KNZ81_RS08670	COG1959	2 iron, 2 sulfur cluster binding
KNZ81_RS08690	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KNZ81_RS08705	COG2172	sigma factor antagonist activity
KNZ81_RS08720	COG1597	lipid kinase activity
KNZ81_RS08735	COG0363	glucosamine-6-phosphate deaminase activity
KNZ81_RS08740	COG1472	Belongs to the glycosyl hydrolase 3 family
KNZ81_RS08745	COG0395	ABC-type sugar transport system, permease component
KNZ81_RS08750	COG1175	transmembrane transport
KNZ81_RS08755	COG2182	Extracellular solute-binding protein
KNZ81_RS08760	COG2188	Transcriptional regulator
KNZ81_RS08765	COG1966	Carbon starvation protein
KNZ81_RS08785	COG2124	cytochrome p450
KNZ81_RS08795	COG0242	peptide deformylase activity
KNZ81_RS08805	COG5662	AntiSigma factor
KNZ81_RS08810	COG1595	DNA-templated transcription, initiation
KNZ81_RS08820	COG2135	peptidase activity
KNZ81_RS08830	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KNZ81_RS08840	COG2076	Multidrug Resistance protein
KNZ81_RS08850	COG0483	inositol monophosphate 1-phosphatase activity
KNZ81_RS08855	COG0753	catalase activity
KNZ81_RS08880	COG1615	UPF0182 protein
KNZ81_RS08890	COG3480	Lon protease (S16) C-terminal proteolytic domain
KNZ81_RS08985	COG0210	DNA helicase
KNZ81_RS09075	COG0513	Belongs to the DEAD box helicase family
KNZ81_RS09085	COG1432	Conserved Protein
KNZ81_RS09095	COG2095	MarC family integral membrane protein
KNZ81_RS09100	COG0613	PHP domain protein
KNZ81_RS09105	COG2814	Major facilitator Superfamily
KNZ81_RS09115	COG0598	Magnesium transport protein CorA
KNZ81_RS09155	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KNZ81_RS09160	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KNZ81_RS09170	COG1595	DNA-templated transcription, initiation
KNZ81_RS09185	COG1024	Enoyl-CoA hydratase
KNZ81_RS09195	COG0519	Catalyzes the synthesis of GMP from XMP
KNZ81_RS09220	COG2207	Transcriptional regulator
KNZ81_RS09230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KNZ81_RS09260	COG0456	acetyltransferase
KNZ81_RS09265	COG2912	Transglutaminase-like superfamily
KNZ81_RS09275	COG1609	Transcriptional regulator
KNZ81_RS09280	COG1172	Belongs to the binding-protein-dependent transport system permease family
KNZ81_RS09310	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KNZ81_RS09335	COG4608	Belongs to the ABC transporter superfamily
KNZ81_RS09345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KNZ81_RS09350	COG0601	transmembrane transport
KNZ81_RS09360	COG4608	Belongs to the ABC transporter superfamily
KNZ81_RS09365	COG0444	Belongs to the ABC transporter superfamily
KNZ81_RS09370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KNZ81_RS09375	COG0601	transmembrane transport
KNZ81_RS09385	COG1217	gtp-binding protein TYPA
KNZ81_RS09490	COG1028	Short-chain dehydrogenase reductase Sdr
KNZ81_RS09495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KNZ81_RS09505	COG3473	Maleate cis-trans isomerase
KNZ81_RS09525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KNZ81_RS09530	COG0765	amino acid transport
KNZ81_RS09535	COG0765	amino acid transport
KNZ81_RS09540	COG1126	abc transporter atp-binding protein
KNZ81_RS09560	COG3397	chitin binding
KNZ81_RS09615	COG0673	inositol 2-dehydrogenase activity
KNZ81_RS09620	COG0179	Fumarylacetoacetate (FAA) hydrolase
KNZ81_RS09625	COG0706	membrane insertase activity
KNZ81_RS09650	COG2271	Major facilitator Superfamily
KNZ81_RS09655	COG2733	membrane
KNZ81_RS09685	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KNZ81_RS09695	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KNZ81_RS09720	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KNZ81_RS09725	COG2197	response regulator
KNZ81_RS09730	COG4585	Histidine kinase
KNZ81_RS09740	COG1131	(ABC) transporter
KNZ81_RS09750	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KNZ81_RS09755	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KNZ81_RS09760	COG1263	PTS System
KNZ81_RS09770	COG1234	tRNA 3'-trailer cleavage
KNZ81_RS09795	COG1113	amino acid transport
KNZ81_RS09810	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KNZ81_RS09820	COG1335	isochorismatase
KNZ81_RS09855	COG0277	FAD linked oxidase domain protein
KNZ81_RS09865	COG3185	4-Hydroxyphenylpyruvate dioxygenase
KNZ81_RS09875	COG1174	glycine betaine transport
KNZ81_RS09880	COG0517	IMP dehydrogenase activity
KNZ81_RS09880	COG1125	glycine betaine transport
KNZ81_RS09885	COG1174	glycine betaine transport
KNZ81_RS09920	COG1136	(ABC) transporter
KNZ81_RS09930	COG2318	DinB family
KNZ81_RS09965	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KNZ81_RS09985	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KNZ81_RS10000	COG3525	Glycosyl hydrolase, family 20, catalytic domain
KNZ81_RS10005	COG0395	ABC-type sugar transport system, permease component
KNZ81_RS10010	COG1175	transmembrane transport
KNZ81_RS10025	COG1678	Uncharacterized ACR, COG1678
KNZ81_RS10030	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KNZ81_RS10035	COG0776	regulation of translation
KNZ81_RS10045	COG3973	AAA domain
KNZ81_RS10045	COG3973	AAA domain
KNZ81_RS10090	COG0583	DNA-binding transcription factor activity
KNZ81_RS10105	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KNZ81_RS10110	COG0793	Belongs to the peptidase S41A family
KNZ81_RS10120	COG2884	Cell division ATP-binding protein ftsE
KNZ81_RS10135	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KNZ81_RS10140	COG0515	serine threonine protein kinase
KNZ81_RS10145	COG0515	serine threonine protein kinase
KNZ81_RS10150	COG1716	ATPase activity
KNZ81_RS10155	COG1653	transport
KNZ81_RS10160	COG1175	transmembrane transport
KNZ81_RS10165	COG0395	ABC-type sugar transport system, permease component
KNZ81_RS10170	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KNZ81_RS10175	COG0438	transferase activity, transferring glycosyl groups
KNZ81_RS10180	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KNZ81_RS10185	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KNZ81_RS10195	COG2226	methyltransferase
KNZ81_RS10210	COG2902	Dehydrogenase
KNZ81_RS10230	COG0583	DNA-binding transcription factor activity
KNZ81_RS10250	COG0653	protein targeting
KNZ81_RS10255	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KNZ81_RS10260	COG3214	Protein conserved in bacteria
KNZ81_RS10265	COG2197	response regulator
KNZ81_RS10270	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KNZ81_RS10280	COG0823	Involved in the tonB-independent uptake of proteins
KNZ81_RS10285	COG5002	protein histidine kinase activity
KNZ81_RS10290	COG0745	RESPONSE REGULATOR receiver
KNZ81_RS10295	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KNZ81_RS10350	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
KNZ81_RS10360	COG1482	cell wall glycoprotein biosynthetic process
KNZ81_RS10370	COG2835	tetraacyldisaccharide 4'-kinase activity
KNZ81_RS10385	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KNZ81_RS10390	COG1620	l-lactate permease
KNZ81_RS10425	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KNZ81_RS10430	COG0778	Nitroreductase
KNZ81_RS10430	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
KNZ81_RS10460	COG1316	TRANSCRIPTIONal
KNZ81_RS10470	COG1316	TRANSCRIPTIONal
KNZ81_RS10480	COG1316	TRANSCRIPTIONal
KNZ81_RS10485	COG3046	protein related to deoxyribodipyrimidine photolyase
KNZ81_RS10490	COG0753	catalase activity
KNZ81_RS10500	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KNZ81_RS10510	COG2072	flavoprotein involved in K transport
KNZ81_RS10550	COG2205	protein histidine kinase activity
KNZ81_RS10555	COG0745	RESPONSE REGULATOR receiver
KNZ81_RS10560	COG3104	oligopeptide transport
KNZ81_RS10570	COG1366	Belongs to the anti-sigma-factor antagonist family
KNZ81_RS10575	COG1191	sigma factor activity
KNZ81_RS10580	COG1228	amidohydrolase
KNZ81_RS10615	COG0395	ABC-type sugar transport system, permease component
KNZ81_RS10675	COG2755	lipolytic protein G-D-S-L family
KNZ81_RS10680	COG0183	Belongs to the thiolase family
KNZ81_RS10705	COG1476	TRANSCRIPTIONal
KNZ81_RS10725	COG1136	(ABC) transporter
KNZ81_RS10730	COG1136	(ABC) transporter
KNZ81_RS10730	COG0577	efflux transmembrane transporter activity
KNZ81_RS10735	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KNZ81_RS10740	COG1252	NADH dehydrogenase
KNZ81_RS10770	COG0148	phosphopyruvate hydratase activity
KNZ81_RS10785	COG2124	cytochrome p450
KNZ81_RS10800	COG0515	serine threonine protein kinase
KNZ81_RS10800	COG2815	serine threonine protein kinase
KNZ81_RS10825	COG1733	regulation of RNA biosynthetic process
KNZ81_RS10865	COG0154	amidase activity
KNZ81_RS10870	COG3226	Transcriptional regulator
KNZ81_RS10880	COG1473	amidohydrolase
KNZ81_RS10935	COG3629	intracellular signal transduction
KNZ81_RS10935	COG3903	Transcriptional regulator
KNZ81_RS10945	COG0477	Major facilitator Superfamily
KNZ81_RS10970	COG2267	carboxylic ester hydrolase activity
KNZ81_RS10980	COG1316	TRANSCRIPTIONal
KNZ81_RS11005	COG0789	Transcriptional regulator
KNZ81_RS11030	COG4585	Histidine kinase
KNZ81_RS11040	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KNZ81_RS11045	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KNZ81_RS11070	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KNZ81_RS11075	COG0193	aminoacyl-tRNA hydrolase activity
KNZ81_RS11085	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KNZ81_RS11105	COG4106	trans-aconitate 2-methyltransferase activity
KNZ81_RS11115	COG2197	response regulator
KNZ81_RS11120	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KNZ81_RS11165	COG0488	(ABC) transporter
KNZ81_RS11170	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KNZ81_RS11175	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KNZ81_RS11180	COG0084	hydrolase, TatD family'
KNZ81_RS11245	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KNZ81_RS11255	COG2409	Drug exporters of the RND superfamily
KNZ81_RS11265	COG0793	Belongs to the peptidase S41A family
KNZ81_RS11265	COG4946	Tricorn protease homolog
KNZ81_RS11275	COG4221	oxidoreductase activity
KNZ81_RS11285	COG2072	flavoprotein involved in K transport
KNZ81_RS11295	COG0708	Exodeoxyribonuclease III
KNZ81_RS11305	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KNZ81_RS11325	COG2197	response regulator
KNZ81_RS11365	COG0315	cyclic pyranopterin monophosphate synthase activity
KNZ81_RS11365	COG0521	Mo-molybdopterin cofactor biosynthetic process
KNZ81_RS11370	COG0315	cyclic pyranopterin monophosphate synthase activity
KNZ81_RS11380	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KNZ81_RS11385	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KNZ81_RS11395	COG3263	regulation of cellular component size
KNZ81_RS11410	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KNZ81_RS11420	COG1970	mechanosensitive ion channel activity
KNZ81_RS11435	COG3191	aminopeptidase activity
KNZ81_RS11455	COG3384	dioxygenase
KNZ81_RS11460	COG1846	Transcriptional regulator
KNZ81_RS11520	COG2050	protein possibly involved in aromatic compounds catabolism
KNZ81_RS11530	COG0183	Belongs to the thiolase family
KNZ81_RS11535	COG1024	Enoyl-CoA hydratase
KNZ81_RS11540	COG1250	3-hydroxyacyl-CoA dehydrogenase
KNZ81_RS11545	COG3396	Phenylacetate-CoA oxygenase
KNZ81_RS11550	COG3460	Phenylacetate-CoA oxygenase
KNZ81_RS11555	COG3396	Phenylacetate-CoA oxygenase
KNZ81_RS11560	COG2151	metal-sulfur cluster biosynthetic enzyme
KNZ81_RS11565	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KNZ81_RS11610	COG0582	viral genome integration into host DNA
KNZ81_RS11655	COG1609	Transcriptional regulator
KNZ81_RS11695	COG1278	Cold shock
KNZ81_RS11775	COG5297	Belongs to the glycosyl hydrolase family 6
KNZ81_RS11790	COG0148	phosphopyruvate hydratase activity
KNZ81_RS11805	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
KNZ81_RS11850	COG0366	Alpha amylase catalytic
KNZ81_RS11860	COG0815	Transfers the fatty acyl group on membrane lipoproteins
KNZ81_RS11880	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KNZ81_RS11885	COG1028	Short-chain dehydrogenase reductase Sdr
KNZ81_RS11895	COG0477	Major facilitator Superfamily
KNZ81_RS11945	COG0515	serine threonine protein kinase
KNZ81_RS11945	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KNZ81_RS11950	COG1309	transcriptional regulator
KNZ81_RS11980	COG1595	DNA-templated transcription, initiation
KNZ81_RS11995	COG2072	flavoprotein involved in K transport
KNZ81_RS12015	COG1366	Belongs to the anti-sigma-factor antagonist family
KNZ81_RS12095	COG4821	SIS domain
KNZ81_RS12105	COG0259	pyridoxamine-phosphate oxidase activity
KNZ81_RS12125	COG1024	Enoyl-CoA hydratase
KNZ81_RS12140	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KNZ81_RS12170	COG0583	DNA-binding transcription factor activity
KNZ81_RS12180	COG0247	lactate metabolic process
KNZ81_RS12180	COG0277	FAD linked oxidase domain protein
KNZ81_RS12185	COG2205	protein histidine kinase activity
KNZ81_RS12205	COG2124	cytochrome p450
KNZ81_RS12215	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KNZ81_RS12340	COG0667	Aldo Keto reductase
KNZ81_RS12365	COG2252	PERMEase
KNZ81_RS12375	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KNZ81_RS12400	COG2814	Major facilitator Superfamily
KNZ81_RS12410	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KNZ81_RS12415	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
KNZ81_RS12430	COG2197	response regulator
KNZ81_RS12435	COG1132	(ABC) transporter
KNZ81_RS12445	COG1132	(ABC) transporter
KNZ81_RS12455	COG0515	serine threonine protein kinase
KNZ81_RS12460	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KNZ81_RS12465	COG1120	ATPase activity
KNZ81_RS12470	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KNZ81_RS12475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KNZ81_RS12485	COG1295	ribonuclease BN
KNZ81_RS12495	COG2124	cytochrome p450
KNZ81_RS12540	COG1061	Type III restriction enzyme res subunit
KNZ81_RS12610	COG3973	AAA domain
KNZ81_RS12660	COG0406	alpha-ribazole phosphatase activity
KNZ81_RS12665	COG1737	Transcriptional regulator
KNZ81_RS12670	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KNZ81_RS12675	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KNZ81_RS12675	COG1263	PTS System
KNZ81_RS12680	COG0667	Aldo Keto reductase
KNZ81_RS12715	COG1278	Cold shock
KNZ81_RS12730	COG0463	Glycosyl transferase, family 2
KNZ81_RS12810	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KNZ81_RS12825	COG1105	Belongs to the carbohydrate kinase PfkB family
KNZ81_RS12850	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KNZ81_RS12875	COG1309	transcriptional regulator
KNZ81_RS12890	COG0577	efflux transmembrane transporter activity
KNZ81_RS12890	COG1136	(ABC) transporter
KNZ81_RS12925	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KNZ81_RS13055	COG1366	Belongs to the anti-sigma-factor antagonist family
KNZ81_RS13060	COG1366	Belongs to the anti-sigma-factor antagonist family
KNZ81_RS13065	COG2172	sigma factor antagonist activity
KNZ81_RS13090	COG0577	efflux transmembrane transporter activity
KNZ81_RS13090	COG1136	(ABC) transporter
KNZ81_RS13095	COG0577	efflux transmembrane transporter activity
KNZ81_RS13120	COG4585	Histidine kinase
KNZ81_RS13125	COG2197	response regulator
KNZ81_RS13130	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KNZ81_RS13135	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KNZ81_RS13155	COG0301	tRNA thio-modification
KNZ81_RS13175	COG0513	Belongs to the DEAD box helicase family
KNZ81_RS13180	COG1278	Cold shock
KNZ81_RS13210	COG2208	phosphoserine phosphatase activity
KNZ81_RS13210	COG2770	Histidine kinase
KNZ81_RS13230	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KNZ81_RS13240	COG1309	transcriptional regulator
KNZ81_RS13280	COG0531	amino acid
KNZ81_RS13285	COG4977	sequence-specific DNA binding
KNZ81_RS13300	COG0477	Major facilitator Superfamily
KNZ81_RS13305	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KNZ81_RS13310	COG0475	glutathione-regulated potassium exporter activity
KNZ81_RS13325	COG1834	amidinotransferase
KNZ81_RS13330	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KNZ81_RS13335	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KNZ81_RS13360	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KNZ81_RS13385	COG3842	ATPase activity
KNZ81_RS13395	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KNZ81_RS13405	COG1253	flavin adenine dinucleotide binding
KNZ81_RS13420	COG0215	cysteine-tRNA ligase activity
KNZ81_RS13435	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KNZ81_RS13455	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KNZ81_RS13460	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KNZ81_RS13465	COG1329	Transcriptional regulator
KNZ81_RS13475	COG0745	RESPONSE REGULATOR receiver
KNZ81_RS13480	COG5002	protein histidine kinase activity
KNZ81_RS13495	COG2076	Multidrug Resistance protein
KNZ81_RS13575	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KNZ81_RS13605	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
KNZ81_RS13625	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KNZ81_RS13630	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KNZ81_RS13645	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
KNZ81_RS13660	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
KNZ81_RS13665	COG0783	Belongs to the Dps family
KNZ81_RS13670	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
KNZ81_RS13675	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KNZ81_RS13705	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KNZ81_RS13730	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KNZ81_RS13735	COG1316	TRANSCRIPTIONal
KNZ81_RS13745	COG0640	Transcriptional regulator
KNZ81_RS13750	COG1028	Short-chain dehydrogenase reductase Sdr
KNZ81_RS13755	COG0789	Transcriptional regulator
KNZ81_RS13760	COG2801	Transposase and inactivated derivatives
KNZ81_RS13760	COG3415	Transposase
KNZ81_RS13770	COG1252	NADH dehydrogenase
KNZ81_RS13790	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KNZ81_RS13800	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KNZ81_RS13815	COG2186	Transcriptional regulator
KNZ81_RS13830	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KNZ81_RS13830	COG0825	malonyl-CoA metabolic process
KNZ81_RS13860	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KNZ81_RS13865	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KNZ81_RS13880	COG0596	Alpha beta hydrolase
KNZ81_RS13890	COG0789	Transcriptional regulator
KNZ81_RS13900	COG1028	Short-chain dehydrogenase reductase Sdr
KNZ81_RS13955	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KNZ81_RS13960	COG1754	DNA topoisomerase type I activity
KNZ81_RS13960	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KNZ81_RS13970	COG2890	protein-(glutamine-N5) methyltransferase activity
KNZ81_RS13985	COG1366	Belongs to the anti-sigma-factor antagonist family
KNZ81_RS13990	COG1205	dead DEAH box helicase
KNZ81_RS13990	COG1111	helicase
KNZ81_RS14050	COG0659	secondary active sulfate transmembrane transporter activity
KNZ81_RS14055	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KNZ81_RS14060	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KNZ81_RS14070	COG2267	carboxylic ester hydrolase activity
KNZ81_RS14100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KNZ81_RS14110	COG0251	oxidation-reduction process
KNZ81_RS14125	COG0003	Pfam Anion-transporting ATPase
KNZ81_RS14145	COG1408	metallophosphoesterase
KNZ81_RS14255	COG1136	(ABC) transporter
KNZ81_RS14255	COG0577	efflux transmembrane transporter activity
KNZ81_RS14270	COG2318	DinB family
KNZ81_RS14295	COG0596	Alpha beta hydrolase
KNZ81_RS14340	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KNZ81_RS14350	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KNZ81_RS14355	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KNZ81_RS14430	COG0666	response to abiotic stimulus
KNZ81_RS14440	COG4585	Histidine kinase
KNZ81_RS14445	COG2197	response regulator
KNZ81_RS14460	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KNZ81_RS14470	COG0596	Alpha beta hydrolase
KNZ81_RS14545	COG0366	Alpha amylase catalytic
KNZ81_RS14545	COG1470	cell adhesion involved in biofilm formation
KNZ81_RS14560	COG0579	oxidoreductase
KNZ81_RS14565	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KNZ81_RS14575	COG0667	Aldo Keto reductase
KNZ81_RS14595	COG2261	transglycosylase associated protein
KNZ81_RS14605	COG0542	response to heat
KNZ81_RS14635	COG0513	Belongs to the DEAD box helicase family
KNZ81_RS14670	COG1643	Atp-dependent helicase
KNZ81_RS14705	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
KNZ81_RS14720	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KNZ81_RS14725	COG0047	phosphoribosylformylglycinamidine synthase activity
KNZ81_RS14730	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KNZ81_RS14765	COG2197	response regulator
KNZ81_RS14775	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KNZ81_RS14790	COG0151	Belongs to the GarS family
KNZ81_RS14815	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KNZ81_RS14875	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KNZ81_RS14910	COG1191	sigma factor activity
KNZ81_RS14915	COG1191	sigma factor activity
KNZ81_RS14930	COG0477	Major facilitator Superfamily
KNZ81_RS14950	COG0477	Major facilitator Superfamily
KNZ81_RS14960	COG0745	RESPONSE REGULATOR receiver
KNZ81_RS14995	COG0318	PFAM AMP-dependent synthetase and ligase
KNZ81_RS15000	COG1595	DNA-templated transcription, initiation
KNZ81_RS15020	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KNZ81_RS15035	COG0653	protein targeting
KNZ81_RS15050	COG0006	proline dipeptidase activity
KNZ81_RS15070	COG1999	signal sequence binding
KNZ81_RS15085	COG2837	iron assimilation
KNZ81_RS15090	COG0077	Prephenate dehydratase
KNZ81_RS15095	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KNZ81_RS15100	COG0561	phosphatase activity
KNZ81_RS15120	COG1131	(ABC) transporter
KNZ81_RS15140	COG0561	phosphatase activity
KNZ81_RS15155	COG4988	ABC transporter
KNZ81_RS15160	COG1294	oxidase, subunit
KNZ81_RS15165	COG1271	oxidase subunit
KNZ81_RS15170	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KNZ81_RS15175	COG1609	Transcriptional regulator
KNZ81_RS15190	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KNZ81_RS15215	COG0662	Cupin 2, conserved barrel domain protein
KNZ81_RS15220	COG1950	PFAM Membrane protein of
KNZ81_RS15225	COG0626	cystathionine gamma-synthase activity
KNZ81_RS15250	COG0456	acetyltransferase
KNZ81_RS15265	COG0110	maltose O-acetyltransferase activity
KNZ81_RS15270	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KNZ81_RS15320	COG0305	Participates in initiation and elongation during chromosome replication
KNZ81_RS15330	COG0359	binds to the 23S rRNA
KNZ81_RS15335	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KNZ81_RS15340	COG0629	single-stranded DNA binding
KNZ81_RS15345	COG0360	Binds together with S18 to 16S ribosomal RNA
KNZ81_RS15370	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KNZ81_RS15395	COG0617	tRNA 3'-terminal CCA addition
KNZ81_RS15410	COG0515	serine threonine protein kinase
KNZ81_RS15410	COG2815	serine threonine protein kinase
KNZ81_RS15415	COG1595	DNA-templated transcription, initiation
KNZ81_RS15425	COG0492	ferredoxin-NADP+ reductase activity
KNZ81_RS15430	COG3118	belongs to the thioredoxin family
KNZ81_RS15445	COG1192	Involved in chromosome partitioning
KNZ81_RS15450	COG2826	transposase and inactivated derivatives, IS30 family
KNZ81_RS15455	COG0357	Ribosomal RNA small subunit methyltransferase G
KNZ81_RS15465	COG0706	membrane insertase activity
KNZ81_RS15470	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
KNZ81_RS15475	COG0594	ribonuclease P activity
KNZ81_RS15480	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KNZ81_RS15485	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KNZ81_RS15490	COG0592	DNA-directed DNA polymerase activity
KNZ81_RS15495	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KNZ81_RS15500	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KNZ81_RS15505	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
KNZ81_RS15510	COG0187	DNA topoisomerase II activity
KNZ81_RS15515	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KNZ81_RS15555	COG0515	serine threonine protein kinase
KNZ81_RS15585	COG1278	Cold shock
KNZ81_RS15615	COG0705	Rhomboid family
KNZ81_RS15640	COG3764	Sortase (surface protein transpeptidase)
KNZ81_RS15645	COG3764	Sortase (surface protein transpeptidase)
KNZ81_RS15650	COG0515	serine threonine protein kinase
KNZ81_RS15670	COG1716	ATPase activity
KNZ81_RS15675	COG1716	ATPase activity
KNZ81_RS15685	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KNZ81_RS15690	COG1733	regulation of RNA biosynthetic process
KNZ81_RS15730	COG1522	sequence-specific DNA binding
KNZ81_RS15755	COG0303	'Molybdopterin
KNZ81_RS15760	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KNZ81_RS15785	COG2826	transposase and inactivated derivatives, IS30 family
KNZ81_RS15790	COG0515	serine threonine protein kinase
KNZ81_RS15795	COG0515	serine threonine protein kinase
KNZ81_RS15810	COG0022	dehydrogenase e1 component
KNZ81_RS15815	COG0508	dehydrogenase complex catalyzes the overall conversion of
KNZ81_RS15830	COG2271	Major facilitator Superfamily
KNZ81_RS15865	COG1362	aminopeptidase activity
KNZ81_RS15885	COG1960	acyl-CoA dehydrogenase activity
KNZ81_RS15895	COG1741	Belongs to the pirin family
KNZ81_RS15910	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KNZ81_RS15920	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KNZ81_RS15955	COG1316	TRANSCRIPTIONal
KNZ81_RS15970	COG2268	Band 7 protein
KNZ81_RS15975	COG1937	Protein conserved in bacteria
KNZ81_RS15985	COG2208	phosphoserine phosphatase activity
KNZ81_RS15985	COG2770	Histidine kinase
KNZ81_RS16015	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KNZ81_RS16025	COG0477	Major facilitator Superfamily
KNZ81_RS16055	COG0247	lactate metabolic process
KNZ81_RS16055	COG2181	nitrate reductase activity
KNZ81_RS16085	COG0717	Belongs to the dCTP deaminase family
KNZ81_RS16125	COG2814	Major facilitator Superfamily
KNZ81_RS16135	COG1695	Transcriptional regulator
KNZ81_RS16170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KNZ81_RS16175	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KNZ81_RS16180	COG1120	ATPase activity
KNZ81_RS16185	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KNZ81_RS16200	COG1131	(ABC) transporter
KNZ81_RS16205	COG1725	Transcriptional regulator
KNZ81_RS16240	COG0443	Heat shock 70 kDa protein
KNZ81_RS16245	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KNZ81_RS16250	COG0484	heat shock protein binding
KNZ81_RS16255	COG0789	Transcriptional regulator
KNZ81_RS16280	COG0477	Major facilitator Superfamily
KNZ81_RS16355	COG0017	Asparaginyl-tRNA synthetase
KNZ81_RS16400	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KNZ81_RS16430	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KNZ81_RS16445	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
KNZ81_RS16495	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KNZ81_RS16510	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KNZ81_RS16515	COG0191	fructose-bisphosphate aldolase activity
KNZ81_RS16520	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KNZ81_RS16525	COG0477	Major facilitator Superfamily
KNZ81_RS16545	COG3844	kynureninase activity
KNZ81_RS16555	COG0702	epimerase
KNZ81_RS16560	COG4585	Histidine kinase
KNZ81_RS16565	COG2197	response regulator
KNZ81_RS16570	COG1335	isochorismatase
KNZ81_RS16585	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KNZ81_RS16600	COG2124	cytochrome p450
KNZ81_RS16645	COG1136	(ABC) transporter
KNZ81_RS16645	COG0577	efflux transmembrane transporter activity
KNZ81_RS16665	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KNZ81_RS16670	COG3251	PFAM MbtH domain protein
KNZ81_RS16675	COG2175	clavaminate synthase activity
KNZ81_RS16730	COG2318	DinB family
KNZ81_RS16755	COG1196	nuclear chromosome segregation
KNZ81_RS16755	COG0741	lytic transglycosylase activity
KNZ81_RS16755	COG0739	heme binding
KNZ81_RS16760	COG0671	phosphoesterase, PA-phosphatase related
KNZ81_RS16775	COG1028	Short-chain dehydrogenase reductase Sdr
KNZ81_RS16785	COG1937	Protein conserved in bacteria
KNZ81_RS16795	COG0306	phosphate transporter
KNZ81_RS16800	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KNZ81_RS16820	COG0406	alpha-ribazole phosphatase activity
KNZ81_RS16820	COG0494	nUDIX hydrolase
KNZ81_RS16825	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KNZ81_RS16830	COG2318	DinB family
KNZ81_RS16835	COG2826	transposase and inactivated derivatives, IS30 family
KNZ81_RS16875	COG2770	Histidine kinase
KNZ81_RS16875	COG2208	phosphoserine phosphatase activity
KNZ81_RS16885	COG0596	Alpha beta hydrolase
KNZ81_RS16890	COG3629	intracellular signal transduction
KNZ81_RS16890	COG3903	Transcriptional regulator
KNZ81_RS16970	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KNZ81_RS16990	COG3842	ATPase activity
KNZ81_RS17000	COG1725	Transcriptional regulator
KNZ81_RS17005	COG4941	Belongs to the sigma-70 factor family
KNZ81_RS17055	COG0456	acetyltransferase
KNZ81_RS17060	COG0737	Belongs to the 5'-nucleotidase family
KNZ81_RS17065	COG0235	Class ii aldolase
KNZ81_RS17070	COG2160	L-arabinose isomerase activity
KNZ81_RS17085	COG1609	Transcriptional regulator
KNZ81_RS17095	COG1129	ABC transporter
KNZ81_RS17100	COG4214	carbohydrate transport
KNZ81_RS17115	COG0745	RESPONSE REGULATOR receiver
KNZ81_RS17120	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KNZ81_RS17125	COG0569	domain protein
KNZ81_RS17130	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KNZ81_RS17135	COG1609	Transcriptional regulator
KNZ81_RS17140	COG0745	RESPONSE REGULATOR receiver
KNZ81_RS17165	COG2897	thiosulfate sulfurtransferase activity
KNZ81_RS17200	COG3485	protocatechuate 3,4-dioxygenase
KNZ81_RS17205	COG0735	belongs to the Fur family
KNZ81_RS17210	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KNZ81_RS17215	COG1490	D-aminoacyl-tRNA deacylase activity
KNZ81_RS17230	COG0789	Transcriptional regulator
KNZ81_RS17320	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KNZ81_RS17350	COG1309	transcriptional regulator
KNZ81_RS17375	COG0791	NLP P60 protein
KNZ81_RS17375	COG1388	LysM domain
KNZ81_RS17375	COG3103	Sh3 type 3 domain protein
KNZ81_RS17385	COG0438	transferase activity, transferring glycosyl groups
KNZ81_RS17410	COG0588	phosphoglycerate mutase activity
KNZ81_RS17415	COG0739	heme binding
KNZ81_RS17450	COG0501	Belongs to the peptidase M48B family
KNZ81_RS17470	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KNZ81_RS17470	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KNZ81_RS17495	COG1289	transmembrane transporter activity
KNZ81_RS17520	COG1012	belongs to the aldehyde dehydrogenase family
KNZ81_RS17525	COG2318	DinB family
KNZ81_RS17535	COG0655	NAD(P)H dehydrogenase (quinone) activity
KNZ81_RS17540	COG0789	Transcriptional regulator
KNZ81_RS17545	COG0586	Pfam SNARE associated Golgi protein
KNZ81_RS17555	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KNZ81_RS17560	COG2027	D-alanyl-D-alanine carboxypeptidase
KNZ81_RS17570	COG0037	tRNA processing
KNZ81_RS17585	COG0302	gtp cyclohydrolase
KNZ81_RS17600	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KNZ81_RS17615	COG1125	glycine betaine transport
KNZ81_RS17615	COG0517	IMP dehydrogenase activity
KNZ81_RS17620	COG1174	glycine betaine transport
KNZ81_RS17625	COG1174	glycine betaine transport
KNZ81_RS17640	COG0477	Major facilitator Superfamily
KNZ81_RS17715	COG1012	belongs to the aldehyde dehydrogenase family
KNZ81_RS17735	COG4585	Histidine kinase
KNZ81_RS17740	COG2197	response regulator
KNZ81_RS17760	COG0649	NAD binding
KNZ81_RS17775	COG2197	response regulator
KNZ81_RS17790	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KNZ81_RS17795	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KNZ81_RS17805	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KNZ81_RS17825	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
KNZ81_RS17855	COG0739	heme binding
KNZ81_RS17860	COG2205	protein histidine kinase activity
KNZ81_RS17865	COG0745	RESPONSE REGULATOR receiver
KNZ81_RS17875	COG1595	DNA-templated transcription, initiation
KNZ81_RS17885	COG0671	phosphoesterase, PA-phosphatase related
KNZ81_RS17895	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
KNZ81_RS17915	COG3415	Transposase
KNZ81_RS17915	COG2801	Transposase and inactivated derivatives
KNZ81_RS17930	COG0248	Ppx GppA phosphatase
KNZ81_RS17940	COG1082	Xylose isomerase domain protein TIM barrel
KNZ81_RS17950	COG0129	dihydroxy-acid dehydratase activity
KNZ81_RS17980	COG1129	ABC transporter
KNZ81_RS17980	COG0842	Transport permease protein
KNZ81_RS17990	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KNZ81_RS17995	COG0180	Tryptophanyl-tRNA synthetase
KNZ81_RS18015	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KNZ81_RS18020	COG2223	nitrite transmembrane transporter activity
KNZ81_RS18025	COG0123	including yeast histone deacetylase and acetoin utilization protein
KNZ81_RS18075	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KNZ81_RS18080	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KNZ81_RS18085	COG0181	hydroxymethylbilane synthase activity
KNZ81_RS18090	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KNZ81_RS18090	COG1648	precorrin-2 dehydrogenase activity
KNZ81_RS18095	COG0113	porphobilinogen synthase activity
KNZ81_RS18115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KNZ81_RS18120	COG0018	arginyl-trna synthetase
KNZ81_RS18125	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
KNZ81_RS18150	COG1690	Belongs to the RtcB family
KNZ81_RS18155	COG0659	secondary active sulfate transmembrane transporter activity
KNZ81_RS18200	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KNZ81_RS18205	COG0406	alpha-ribazole phosphatase activity
KNZ81_RS18215	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KNZ81_RS18220	COG0785	Cytochrome C biogenesis protein
KNZ81_RS18230	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KNZ81_RS18245	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
KNZ81_RS18250	COG0109	protoheme IX farnesyltransferase activity
KNZ81_RS18255	COG0163	prenyltransferase activity
KNZ81_RS18270	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
KNZ81_RS18290	COG1301	dicarboxylic acid transport
KNZ81_RS18365	COG0183	Belongs to the thiolase family
KNZ81_RS18375	COG1278	Cold shock
KNZ81_RS18380	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
KNZ81_RS18400	COG1674	ftsk spoiiie
KNZ81_RS18525	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
KNZ81_RS18570	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
KNZ81_RS18580	COG2226	methyltransferase
KNZ81_RS18605	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KNZ81_RS18610	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KNZ81_RS18615	COG0649	NAD binding
KNZ81_RS18625	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KNZ81_RS18630	COG1034	ATP synthesis coupled electron transport
KNZ81_RS18635	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
KNZ81_RS18640	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KNZ81_RS18645	COG0839	Belongs to the complex I subunit 6 family
KNZ81_RS18650	COG0713	ATP synthesis coupled electron transport
KNZ81_RS18655	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KNZ81_RS18665	COG1007	ATP synthesis coupled electron transport
KNZ81_RS18670	COG0514	ATP-dependent DNA helicase (RecQ)
KNZ81_RS18685	COG0561	phosphatase activity
KNZ81_RS18705	COG3104	oligopeptide transport
KNZ81_RS18710	COG0142	geranyltranstransferase activity
KNZ81_RS18730	COG0488	(ABC) transporter
KNZ81_RS18740	COG0702	epimerase
KNZ81_RS18745	COG1733	regulation of RNA biosynthetic process
KNZ81_RS18750	COG1013	pyruvate-flavodoxin oxidoreductase activity
KNZ81_RS18755	COG0674	pyruvate-flavodoxin oxidoreductase activity
KNZ81_RS18755	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KNZ81_RS18760	COG2197	response regulator
KNZ81_RS18765	COG4585	Histidine kinase
KNZ81_RS18775	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KNZ81_RS18780	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KNZ81_RS18785	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KNZ81_RS18790	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
KNZ81_RS18795	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KNZ81_RS18800	COG0839	Belongs to the complex I subunit 6 family
KNZ81_RS18805	COG0713	ATP synthesis coupled electron transport
KNZ81_RS18810	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KNZ81_RS18820	COG1007	ATP synthesis coupled electron transport
KNZ81_RS18825	COG0501	Belongs to the peptidase M48B family
KNZ81_RS18830	COG3304	Inner membrane component domain
KNZ81_RS18835	COG2261	transglycosylase associated protein
KNZ81_RS18840	COG1666	GTP binding
KNZ81_RS18855	COG0702	epimerase
KNZ81_RS18860	COG0402	S-adenosylhomocysteine deaminase activity
KNZ81_RS18875	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KNZ81_RS18880	COG2030	dehydratase
KNZ81_RS18890	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KNZ81_RS18900	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KNZ81_RS18905	COG0436	Aminotransferase
KNZ81_RS18930	COG0081	regulation of translation
KNZ81_RS18940	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KNZ81_RS18945	COG0222	ribosome binding
KNZ81_RS18950	COG0085	RNA polymerase activity
KNZ81_RS18955	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KNZ81_RS18990	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KNZ81_RS18995	COG0049	tRNA binding
KNZ81_RS19000	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KNZ81_RS19020	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
KNZ81_RS19030	COG0051	transcription antitermination factor activity, RNA binding
KNZ81_RS19035	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KNZ81_RS19040	COG0088	Forms part of the polypeptide exit tunnel
KNZ81_RS19045	COG0089	rRNA binding
KNZ81_RS19050	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KNZ81_RS19055	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KNZ81_RS19060	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KNZ81_RS19065	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KNZ81_RS19070	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KNZ81_RS19075	COG0255	Belongs to the universal ribosomal protein uL29 family
KNZ81_RS19080	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KNZ81_RS19085	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KNZ81_RS19090	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KNZ81_RS19095	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KNZ81_RS19100	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KNZ81_RS19105	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KNZ81_RS19110	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KNZ81_RS19115	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KNZ81_RS19120	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KNZ81_RS19125	COG1841	ribosomal large subunit assembly
KNZ81_RS19130	COG0200	Binds to the 23S rRNA
KNZ81_RS19135	COG0201	protein transport
KNZ81_RS19140	COG0563	adenylate kinase activity
KNZ81_RS19150	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KNZ81_RS19155	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KNZ81_RS19160	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KNZ81_RS19165	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KNZ81_RS19175	COG0203	ribosomal protein L17
KNZ81_RS19180	COG0101	tRNA pseudouridine synthase activity
KNZ81_RS19190	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KNZ81_RS19195	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KNZ81_RS19200	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KNZ81_RS19205	COG1072	(Pantothenic acid kinase))
KNZ81_RS19220	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KNZ81_RS19230	COG4977	sequence-specific DNA binding
KNZ81_RS19240	COG0736	holo-[acyl-carrier-protein] synthase activity
KNZ81_RS19305	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KNZ81_RS19315	COG0802	atpase or kinase
KNZ81_RS19340	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KNZ81_RS19375	COG0726	polysaccharide deacetylase
KNZ81_RS19390	COG4221	oxidoreductase activity
KNZ81_RS19395	COG0583	DNA-binding transcription factor activity
KNZ81_RS19405	COG2197	response regulator
KNZ81_RS19410	COG1595	DNA-templated transcription, initiation
KNZ81_RS19420	COG0516	GMP reductase activity
KNZ81_RS19430	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KNZ81_RS19470	COG1012	belongs to the aldehyde dehydrogenase family
KNZ81_RS19490	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KNZ81_RS19490	COG0519	Catalyzes the synthesis of GMP from XMP
KNZ81_RS19500	COG1028	Short-chain dehydrogenase reductase Sdr
KNZ81_RS19525	COG2197	response regulator
KNZ81_RS19530	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KNZ81_RS19595	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KNZ81_RS19640	COG2066	Belongs to the glutaminase family
KNZ81_RS19645	COG0739	heme binding
KNZ81_RS19645	COG1196	nuclear chromosome segregation
KNZ81_RS19645	COG0741	lytic transglycosylase activity
KNZ81_RS19650	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
KNZ81_RS19655	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KNZ81_RS19655	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KNZ81_RS19670	COG0714	Associated with various cellular activities
KNZ81_RS19675	COG2425	protein containing a von Willebrand factor type A (vWA) domain
KNZ81_RS19680	COG3552	Protein containing von Willebrand factor type A (VWA) domain
KNZ81_RS19685	COG0045	succinate-CoA ligase (ADP-forming) activity
KNZ81_RS19715	COG0138	bifunctional purine biosynthesis protein purh
KNZ81_RS19725	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KNZ81_RS19735	COG2197	response regulator
KNZ81_RS19760	COG0039	L-malate dehydrogenase activity
KNZ81_RS19785	COG1012	belongs to the aldehyde dehydrogenase family
KNZ81_RS19795	COG0517	IMP dehydrogenase activity
KNZ81_RS19795	COG4175	Glycine betaine
KNZ81_RS19825	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KNZ81_RS19830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KNZ81_RS19840	COG0754	glutathionylspermidine amidase activity
KNZ81_RS19850	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KNZ81_RS19885	COG0180	Tryptophanyl-tRNA synthetase
KNZ81_RS19930	COG1295	ribonuclease BN
KNZ81_RS19935	COG1686	Belongs to the peptidase S11 family
KNZ81_RS19945	COG1408	metallophosphoesterase
KNZ81_RS19970	COG0730	response to heat
KNZ81_RS19985	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KNZ81_RS19985	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KNZ81_RS19995	COG1937	Protein conserved in bacteria
KNZ81_RS20010	COG1309	transcriptional regulator
KNZ81_RS20025	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KNZ81_RS20030	COG1053	succinate dehydrogenase
KNZ81_RS20040	COG2009	succinate dehydrogenase
KNZ81_RS20080	COG1215	transferase activity, transferring glycosyl groups
KNZ81_RS20085	COG1595	DNA-templated transcription, initiation
KNZ81_RS20110	COG1028	Short-chain dehydrogenase reductase Sdr
KNZ81_RS20140	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KNZ81_RS20160	COG1216	Glycosyl transferase, family 2
KNZ81_RS20170	COG1083	cytidylyl-transferase
KNZ81_RS20175	COG2089	acid synthase
KNZ81_RS20185	COG1473	amidohydrolase
KNZ81_RS20185	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
KNZ81_RS20230	COG1744	ABC transporter substrate-binding protein PnrA-like
KNZ81_RS20235	COG3845	ABC transporter
KNZ81_RS20240	COG4603	Belongs to the binding-protein-dependent transport system permease family
KNZ81_RS20245	COG1079	Belongs to the binding-protein-dependent transport system permease family
KNZ81_RS20285	COG2814	Major facilitator Superfamily
KNZ81_RS20290	COG0583	DNA-binding transcription factor activity
KNZ81_RS20300	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KNZ81_RS20325	COG2205	protein histidine kinase activity
KNZ81_RS20330	COG0745	RESPONSE REGULATOR receiver
KNZ81_RS20335	COG1595	DNA-templated transcription, initiation
KNZ81_RS20355	COG1012	belongs to the aldehyde dehydrogenase family
KNZ81_RS20375	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KNZ81_RS20410	COG4770	biotin carboxylase activity
KNZ81_RS20420	COG0424	maF-like protein
KNZ81_RS20435	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KNZ81_RS20445	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
KNZ81_RS20450	COG1024	Enoyl-CoA hydratase
KNZ81_RS20460	COG2986	histidine ammonia-lyase
KNZ81_RS20480	COG2318	DinB family
KNZ81_RS20505	COG2255	four-way junction helicase activity
KNZ81_RS20510	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KNZ81_RS20525	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KNZ81_RS20535	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KNZ81_RS20565	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KNZ81_RS20575	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KNZ81_RS20620	COG1331	Highly conserved protein containing a thioredoxin domain
KNZ81_RS20640	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
KNZ81_RS20670	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
KNZ81_RS20685	COG1414	Transcriptional regulator
KNZ81_RS20690	COG0251	oxidation-reduction process
KNZ81_RS20705	COG0300	oxidoreductase activity
KNZ81_RS20710	COG1028	Short-chain dehydrogenase reductase Sdr
KNZ81_RS20760	COG2894	cell division
KNZ81_RS20790	COG2197	response regulator
KNZ81_RS20825	COG0656	L-ascorbic acid biosynthetic process
KNZ81_RS20840	COG3548	integral membrane protein
KNZ81_RS20850	COG0667	Aldo Keto reductase
KNZ81_RS20855	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KNZ81_RS20860	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KNZ81_RS20880	COG0450	alkyl hydroperoxide reductase
KNZ81_RS20885	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KNZ81_RS20895	COG1136	(ABC) transporter
KNZ81_RS20915	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KNZ81_RS20930	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KNZ81_RS20930	COG4106	trans-aconitate 2-methyltransferase activity
KNZ81_RS20940	COG0114	fumarate hydratase activity
KNZ81_RS20950	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
KNZ81_RS20950	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
KNZ81_RS20955	COG0515	serine threonine protein kinase
KNZ81_RS20980	COG0778	Nitroreductase
KNZ81_RS20985	COG1722	exodeoxyribonuclease VII activity
KNZ81_RS20990	COG1570	exodeoxyribonuclease VII activity
KNZ81_RS21000	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KNZ81_RS21015	COG0012	GTP binding
KNZ81_RS21025	COG0406	alpha-ribazole phosphatase activity
KNZ81_RS21050	COG0745	RESPONSE REGULATOR receiver
KNZ81_RS21105	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KNZ81_RS21110	COG4977	sequence-specific DNA binding
KNZ81_RS21125	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KNZ81_RS21150	COG3486	L-lysine 6-monooxygenase (NADPH) activity
KNZ81_RS21175	COG1028	Short-chain dehydrogenase reductase Sdr
KNZ81_RS21185	COG3655	Transcriptional regulator
KNZ81_RS21225	COG1960	acyl-CoA dehydrogenase activity
KNZ81_RS21240	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KNZ81_RS21245	COG1309	transcriptional regulator
KNZ81_RS21255	COG1946	Acyl-CoA thioesterase
KNZ81_RS21300	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KNZ81_RS21310	COG3960	tartronate-semialdehyde synthase activity
KNZ81_RS21330	COG1472	Belongs to the glycosyl hydrolase 3 family
KNZ81_RS21335	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KNZ81_RS21375	COG3718	enzyme involved in inositol metabolism
KNZ81_RS21380	COG3962	Belongs to the TPP enzyme family
KNZ81_RS21400	COG1131	(ABC) transporter
KNZ81_RS21430	COG3629	intracellular signal transduction
KNZ81_RS21430	COG3903	Transcriptional regulator
KNZ81_RS21460	COG0483	inositol monophosphate 1-phosphatase activity
KNZ81_RS21515	COG0629	single-stranded DNA binding
KNZ81_RS21545	COG1136	(ABC) transporter
KNZ81_RS21565	COG0667	Aldo Keto reductase
KNZ81_RS21570	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KNZ81_RS21600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KNZ81_RS21615	COG1486	melibiose metabolic process
KNZ81_RS21625	COG0668	transmembrane transport
KNZ81_RS21640	COG3525	Glycosyl hydrolase, family 20, catalytic domain
KNZ81_RS21640	COG3291	Pkd domain containing protein
KNZ81_RS21660	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KNZ81_RS21685	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KNZ81_RS21695	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KNZ81_RS21710	COG0318	PFAM AMP-dependent synthetase and ligase
KNZ81_RS21715	COG1012	belongs to the aldehyde dehydrogenase family
KNZ81_RS21720	COG2826	transposase and inactivated derivatives, IS30 family
KNZ81_RS21725	COG1819	glycosyl
KNZ81_RS21750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KNZ81_RS21760	COG1028	Short-chain dehydrogenase reductase Sdr
KNZ81_RS21760	COG3321	synthase
KNZ81_RS21760	COG4221	oxidoreductase activity
KNZ81_RS21760	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KNZ81_RS21775	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
KNZ81_RS21775	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KNZ81_RS21800	COG0583	DNA-binding transcription factor activity
KNZ81_RS21805	COG4266	Belongs to the allantoicase family
KNZ81_RS21830	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KNZ81_RS21835	COG0076	glutamate decarboxylase activity
KNZ81_RS21840	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KNZ81_RS21845	COG1113	amino acid transport
KNZ81_RS21850	COG1113	amino acid transport
KNZ81_RS21855	COG1268	BioY protein
KNZ81_RS21875	COG1113	amino acid transport
KNZ81_RS21890	COG4552	Acetyltransferase involved in intracellular survival and related
KNZ81_RS21900	COG0475	glutathione-regulated potassium exporter activity
KNZ81_RS21905	COG3594	Acyltransferase
KNZ81_RS21925	COG0544	peptidyl-prolyl cis-trans isomerase activity
KNZ81_RS21930	COG0740	serine-type endopeptidase activity
KNZ81_RS21935	COG0740	serine-type endopeptidase activity
KNZ81_RS21940	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KNZ81_RS21950	COG0525	valine-tRNA ligase activity
KNZ81_RS21955	COG0285	dihydrofolate synthase activity
KNZ81_RS21965	COG0105	UTP biosynthetic process
KNZ81_RS21970	COG1077	Cell shape determining protein MreB Mrl
KNZ81_RS21990	COG0772	Belongs to the SEDS family
KNZ81_RS22020	COG1530	ribonuclease E activity
KNZ81_RS22025	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KNZ81_RS22030	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KNZ81_RS22035	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KNZ81_RS22055	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KNZ81_RS22065	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KNZ81_RS22085	COG0501	Belongs to the peptidase M48B family
KNZ81_RS22100	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KNZ81_RS22110	COG0799	negative regulation of ribosome biogenesis
KNZ81_RS22115	COG0588	phosphoglycerate mutase activity
KNZ81_RS22140	COG0495	leucyl-tRNA aminoacylation
KNZ81_RS22150	COG1307	EDD domain protein, DegV family
KNZ81_RS22170	COG2353	YceI-like domain
KNZ81_RS22185	COG0268	Binds directly to 16S ribosomal RNA
KNZ81_RS22190	COG0481	GTPase activity
KNZ81_RS22220	COG0484	heat shock protein binding
KNZ81_RS22235	COG4946	Tricorn protease homolog
KNZ81_RS22235	COG0793	Belongs to the peptidase S41A family
KNZ81_RS22240	COG0537	adenosine 5'-monophosphoramidase activity
KNZ81_RS22245	COG1234	tRNA 3'-trailer cleavage
KNZ81_RS22265	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KNZ81_RS22270	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KNZ81_RS22295	COG1486	melibiose metabolic process
KNZ81_RS22300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KNZ81_RS22320	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KNZ81_RS22330	COG2315	Protein conserved in bacteria
KNZ81_RS22340	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KNZ81_RS22355	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KNZ81_RS22365	COG1381	Involved in DNA repair and RecF pathway recombination
KNZ81_RS22370	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KNZ81_RS22380	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KNZ81_RS22385	COG1121	(ABC) transporter
KNZ81_RS22395	COG0423	glycine-tRNA ligase activity
KNZ81_RS22460	COG3467	pyridoxamine 5'-phosphate
KNZ81_RS22475	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
KNZ81_RS22480	COG1846	Transcriptional regulator
KNZ81_RS22480	COG1940	carbohydrate kinase activity
KNZ81_RS22485	COG0574	Belongs to the PEP-utilizing enzyme family
KNZ81_RS22485	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KNZ81_RS22500	COG1324	tolerance protein
KNZ81_RS22510	COG2226	methyltransferase
KNZ81_RS22515	COG4106	trans-aconitate 2-methyltransferase activity
KNZ81_RS22570	COG1070	Carbohydrate kinase
KNZ81_RS22590	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KNZ81_RS22595	COG0358	DNA primase activity
KNZ81_RS22605	COG3290	protein histidine kinase activity
KNZ81_RS22610	COG4565	transcriptional regulatory protein
KNZ81_RS22615	COG2851	Citrate transporter
KNZ81_RS22630	COG0232	Belongs to the dGTPase family. Type 2 subfamily
KNZ81_RS22645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KNZ81_RS22675	COG1028	Short-chain dehydrogenase reductase Sdr
KNZ81_RS22690	COG2890	protein-(glutamine-N5) methyltransferase activity
KNZ81_RS22705	COG1077	Cell shape determining protein MreB Mrl
KNZ81_RS22725	COG2130	NADP-dependent
KNZ81_RS22730	COG1764	response to oxidative stress
KNZ81_RS22760	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KNZ81_RS22765	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KNZ81_RS22770	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KNZ81_RS22785	COG1741	Belongs to the pirin family
KNZ81_RS22795	COG0789	Transcriptional regulator
KNZ81_RS22800	COG0667	Aldo Keto reductase
KNZ81_RS22815	COG2197	response regulator
KNZ81_RS22820	COG4585	Histidine kinase
KNZ81_RS22840	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
KNZ81_RS22885	COG1358	cellular component organization or biogenesis
KNZ81_RS22900	COG0586	Pfam SNARE associated Golgi protein
KNZ81_RS23015	COG3845	ABC transporter
KNZ81_RS23035	COG0438	transferase activity, transferring glycosyl groups
KNZ81_RS23065	COG0477	Major facilitator Superfamily
KNZ81_RS23075	COG1960	acyl-CoA dehydrogenase activity
KNZ81_RS23105	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KNZ81_RS23125	COG0800	Aldolase
KNZ81_RS23130	COG3022	response to hydroperoxide
KNZ81_RS23185	COG0076	glutamate decarboxylase activity
KNZ81_RS23200	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KNZ81_RS23225	COG4974	Belongs to the 'phage' integrase family
KNZ81_RS23275	COG0384	phenazine biosynthesis protein PhzF
KNZ81_RS23280	COG1028	Short-chain dehydrogenase reductase Sdr
KNZ81_RS23290	COG0076	glutamate decarboxylase activity
KNZ81_RS23300	COG2814	Major facilitator Superfamily
KNZ81_RS23305	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KNZ81_RS23315	COG1834	amidinotransferase
KNZ81_RS23335	COG1120	ATPase activity
KNZ81_RS23340	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KNZ81_RS23390	COG1994	Peptidase M50
KNZ81_RS23395	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KNZ81_RS23405	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KNZ81_RS23405	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KNZ81_RS23410	COG2132	Multicopper oxidase
KNZ81_RS23430	COG0174	glutamine synthetase
KNZ81_RS23455	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KNZ81_RS23485	COG1609	Transcriptional regulator
KNZ81_RS23490	COG2182	Extracellular solute-binding protein
KNZ81_RS23495	COG1175	transmembrane transport
KNZ81_RS23500	COG0395	ABC-type sugar transport system, permease component
KNZ81_RS23505	COG0366	Alpha amylase catalytic
KNZ81_RS23525	COG1309	transcriptional regulator
KNZ81_RS23560	COG0745	RESPONSE REGULATOR receiver
KNZ81_RS23600	COG1012	belongs to the aldehyde dehydrogenase family
KNZ81_RS23665	COG2326	polyphosphate kinase activity
KNZ81_RS23680	COG2376	Dihydroxyacetone kinase
KNZ81_RS23690	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KNZ81_RS23720	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KNZ81_RS23725	COG0321	lipoyl(octanoyl) transferase activity
KNZ81_RS23775	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
KNZ81_RS23785	COG0508	dehydrogenase complex catalyzes the overall conversion of
KNZ81_RS23790	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KNZ81_RS23795	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KNZ81_RS23800	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
KNZ81_RS23810	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
KNZ81_RS23855	COG2197	response regulator
KNZ81_RS23860	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KNZ81_RS23865	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KNZ81_RS23890	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KNZ81_RS23895	COG1104	cysteine desulfurase activity
KNZ81_RS23900	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KNZ81_RS23905	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KNZ81_RS23915	COG1376	ErfK ybiS ycfS ynhG family protein
KNZ81_RS23925	COG1845	cytochrome c oxidase, subunit III
KNZ81_RS23930	COG2010	Cytochrome c
KNZ81_RS23935	COG0723	plastoquinol--plastocyanin reductase activity
KNZ81_RS23940	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KNZ81_RS23945	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KNZ81_RS23950	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KNZ81_RS23955	COG1929	Belongs to the glycerate kinase type-1 family
KNZ81_RS23965	COG0745	RESPONSE REGULATOR receiver
KNZ81_RS23970	COG5002	protein histidine kinase activity
KNZ81_RS23985	COG0705	Rhomboid family
KNZ81_RS24020	COG0438	transferase activity, transferring glycosyl groups
KNZ81_RS24040	COG0003	Pfam Anion-transporting ATPase
KNZ81_RS24050	COG1940	carbohydrate kinase activity
KNZ81_RS24075	COG4585	Histidine kinase
KNZ81_RS24080	COG2197	response regulator
KNZ81_RS24085	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KNZ81_RS24095	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
KNZ81_RS24100	COG0243	molybdopterin cofactor binding
KNZ81_RS24105	COG2193	ferroxidase activity
KNZ81_RS24110	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KNZ81_RS24115	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KNZ81_RS24120	COG0515	serine threonine protein kinase
KNZ81_RS24120	COG2815	serine threonine protein kinase
KNZ81_RS24125	COG2022	thiamine diphosphate biosynthetic process
KNZ81_RS24135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KNZ81_RS24135	COG2022	thiamine diphosphate biosynthetic process
KNZ81_RS24140	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KNZ81_RS24150	COG0352	thiamine-phosphate diphosphorylase activity
KNZ81_RS24170	COG1309	transcriptional regulator
KNZ81_RS24185	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KNZ81_RS24195	COG3547	Transposase (IS116 IS110 IS902 family)
KNZ81_RS24210	COG0714	Associated with various cellular activities
KNZ81_RS24220	COG0275	rRNA processing
KNZ81_RS24230	COG0768	penicillin binding
KNZ81_RS24235	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KNZ81_RS24245	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KNZ81_RS24250	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KNZ81_RS24260	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KNZ81_RS24265	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KNZ81_RS24270	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KNZ81_RS24275	COG1496	oxidoreductase activity
KNZ81_RS24280	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KNZ81_RS24285	COG1799	cell septum assembly
KNZ81_RS24295	COG3599	regulation of cell shape
KNZ81_RS24300	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KNZ81_RS24310	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KNZ81_RS24320	COG2153	protein acetylation
KNZ81_RS24335	COG0515	serine threonine protein kinase
KNZ81_RS24355	COG0587	DNA-directed DNA polymerase activity
KNZ81_RS24365	COG1432	Conserved Protein
KNZ81_RS24385	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KNZ81_RS24405	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KNZ81_RS24410	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KNZ81_RS24415	COG0131	Imidazoleglycerol-phosphate dehydratase
KNZ81_RS24425	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KNZ81_RS24430	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KNZ81_RS24435	COG0251	oxidation-reduction process
KNZ81_RS24440	COG0107	imidazoleglycerol-phosphate synthase activity
KNZ81_RS24450	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KNZ81_RS24460	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KNZ81_RS24470	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KNZ81_RS24490	COG0134	indole-3-glycerol-phosphate synthase activity
KNZ81_RS24495	COG0133	tryptophan synthase activity
KNZ81_RS24500	COG0159	tryptophan synthase activity
KNZ81_RS24510	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KNZ81_RS24520	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KNZ81_RS24555	COG0067	glutamate synthase
KNZ81_RS24555	COG0069	glutamate synthase activity
KNZ81_RS24555	COG0070	glutamate synthase
KNZ81_RS24570	COG1278	Cold shock
KNZ81_RS24575	COG0513	Belongs to the DEAD box helicase family
KNZ81_RS24585	COG1605	Chorismate mutase
KNZ81_RS24585	COG0287	Prephenate dehydrogenase
KNZ81_RS24615	COG3486	L-lysine 6-monooxygenase (NADPH) activity
KNZ81_RS24620	COG0737	Belongs to the 5'-nucleotidase family
KNZ81_RS24660	COG0559	Belongs to the binding-protein-dependent transport system permease family
KNZ81_RS24675	COG2050	protein possibly involved in aromatic compounds catabolism
KNZ81_RS24695	COG1643	Atp-dependent helicase
KNZ81_RS24700	COG2226	methyltransferase
KNZ81_RS24720	COG0237	dephospho-CoA kinase activity
KNZ81_RS24735	COG1288	antiporter activity
KNZ81_RS24785	COG0477	Major facilitator Superfamily
KNZ81_RS24795	COG0584	glycerophosphoryl diester phosphodiesterase
KNZ81_RS24805	COG0556	nucleotide-excision repair
KNZ81_RS24825	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KNZ81_RS24840	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KNZ81_RS24855	COG0322	excinuclease ABC activity
KNZ81_RS24860	COG1660	Displays ATPase and GTPase activities
KNZ81_RS24870	COG1481	regulation of sporulation
KNZ81_RS24875	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KNZ81_RS24880	COG0126	phosphoglycerate kinase activity
KNZ81_RS24885	COG0149	triose-phosphate isomerase activity
KNZ81_RS24890	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KNZ81_RS24900	COG0166	Belongs to the GPI family
KNZ81_RS24905	COG0363	glucosamine-6-phosphate deaminase activity
KNZ81_RS24920	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KNZ81_RS24925	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KNZ81_RS24930	COG0109	protoheme IX farnesyltransferase activity
KNZ81_RS24955	COG1131	(ABC) transporter
KNZ81_RS24970	COG0719	Fe-S assembly protein
KNZ81_RS24980	COG0396	ATPase activity
KNZ81_RS24985	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KNZ81_RS24990	COG0822	iron-sulfur transferase activity
KNZ81_RS25000	COG2171	N-acyltransferase activity
KNZ81_RS25040	COG2197	response regulator
KNZ81_RS25075	COG1902	pentaerythritol trinitrate reductase activity
KNZ81_RS25085	COG1917	Cupin 2, conserved barrel domain protein
KNZ81_RS25095	COG0456	acetyltransferase
KNZ81_RS25100	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KNZ81_RS25130	COG1797	cobyrinic acid a,c-diamide synthase activity
KNZ81_RS25145	COG1492	cobalamin metabolic process
KNZ81_RS25165	COG0235	Class ii aldolase
KNZ81_RS25185	COG0488	(ABC) transporter
KNZ81_RS25245	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KNZ81_RS25265	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KNZ81_RS25280	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KNZ81_RS25285	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KNZ81_RS25295	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
KNZ81_RS25315	COG2261	transglycosylase associated protein
KNZ81_RS25320	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KNZ81_RS25330	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KNZ81_RS25340	COG2186	Transcriptional regulator
KNZ81_RS25345	COG2807	transmembrane transport
KNZ81_RS25365	COG0560	Phosphoserine phosphatase
KNZ81_RS25365	COG3830	Belongs to the UPF0237 family
KNZ81_RS25370	COG1131	(ABC) transporter
KNZ81_RS25370	COG1716	ATPase activity
KNZ81_RS25370	COG0842	Transport permease protein
KNZ81_RS25390	COG2197	response regulator
KNZ81_RS25405	COG1119	ATPase activity
KNZ81_RS25425	COG1881	PFAM PEBP family protein
KNZ81_RS25435	COG2094	Belongs to the DNA glycosylase MPG family
KNZ81_RS25470	COG0647	UMP catabolic process
KNZ81_RS25490	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KNZ81_RS25495	COG0497	DNA recombination
KNZ81_RS25525	COG3387	PFAM Glycoside hydrolase 15-related
KNZ81_RS25530	COG0504	CTP synthase activity
KNZ81_RS25535	COG0494	nUDIX hydrolase
KNZ81_RS25545	COG0686	Belongs to the AlaDH PNT family
KNZ81_RS25560	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KNZ81_RS25565	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KNZ81_RS25570	COG1187	pseudouridine synthase activity
KNZ81_RS25580	COG1397	ADP-ribosylglycohydrolase
KNZ81_RS25600	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KNZ81_RS25610	COG1160	GTP binding
KNZ81_RS25630	COG0438	transferase activity, transferring glycosyl groups
KNZ81_RS25650	COG0671	phosphoesterase, PA-phosphatase related
KNZ81_RS25660	COG0477	Major facilitator Superfamily
KNZ81_RS25665	COG1799	cell septum assembly
KNZ81_RS25695	COG0330	HflC and HflK could
KNZ81_RS25710	COG0587	DNA-directed DNA polymerase activity
KNZ81_RS25715	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KNZ81_RS25790	COG1216	Glycosyl transferase, family 2
KNZ81_RS25810	COG2755	lipolytic protein G-D-S-L family
KNZ81_RS25815	COG2815	serine threonine protein kinase
KNZ81_RS25815	COG0515	serine threonine protein kinase
KNZ81_RS25830	COG3973	AAA domain
KNZ81_RS25835	COG2188	Transcriptional regulator
KNZ81_RS25840	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
KNZ81_RS25850	COG1309	transcriptional regulator
KNZ81_RS25880	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KNZ81_RS25915	COG0436	Aminotransferase
KNZ81_RS25945	COG3876	Protein conserved in bacteria
KNZ81_RS25955	COG0488	(ABC) transporter
KNZ81_RS25970	COG0318	PFAM AMP-dependent synthetase and ligase
KNZ81_RS25980	COG1960	acyl-CoA dehydrogenase activity
KNZ81_RS26000	COG2149	membrane
KNZ81_RS26005	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
KNZ81_RS26020	COG3573	Dehydrogenase
KNZ81_RS26045	COG3265	gluconokinase activity
KNZ81_RS26060	COG3012	SEC-C Motif Domain Protein
KNZ81_RS26065	COG3189	MarR family transcriptional regulator
KNZ81_RS26075	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KNZ81_RS26115	COG0667	Aldo Keto reductase
KNZ81_RS26120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KNZ81_RS26130	COG0598	Magnesium transport protein CorA
KNZ81_RS26150	COG0215	cysteine-tRNA ligase activity
KNZ81_RS26165	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KNZ81_RS26170	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KNZ81_RS26175	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KNZ81_RS26185	COG1410	methionine synthase
KNZ81_RS26185	COG0646	methionine synthase
KNZ81_RS26195	COG0747	negative chemotaxis
KNZ81_RS26200	COG2197	response regulator
KNZ81_RS26210	COG1994	Peptidase M50
KNZ81_RS26210	COG0517	IMP dehydrogenase activity
KNZ81_RS26230	COG1222	aaa ATPase
KNZ81_RS26235	COG4122	O-methyltransferase activity
KNZ81_RS26245	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
KNZ81_RS26250	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
KNZ81_RS26255	COG1609	Transcriptional regulator
KNZ81_RS26265	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
KNZ81_RS26300	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KNZ81_RS26305	COG0805	protein transport
KNZ81_RS26320	COG2124	cytochrome p450
KNZ81_RS26350	COG0564	pseudouridine synthase activity
KNZ81_RS26360	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KNZ81_RS26370	COG1595	DNA-templated transcription, initiation
KNZ81_RS26380	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KNZ81_RS26385	COG4175	Glycine betaine
KNZ81_RS26385	COG0517	IMP dehydrogenase activity
KNZ81_RS26390	COG4176	ABC-type proline glycine betaine transport system permease component
KNZ81_RS26410	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KNZ81_RS26415	COG0531	amino acid
KNZ81_RS26420	COG2186	Transcriptional regulator
KNZ81_RS26425	COG0174	glutamine synthetase
KNZ81_RS26430	COG1012	belongs to the aldehyde dehydrogenase family
KNZ81_RS26470	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KNZ81_RS26480	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KNZ81_RS26485	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KNZ81_RS26490	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KNZ81_RS26495	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KNZ81_RS26505	COG5002	protein histidine kinase activity
KNZ81_RS26510	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KNZ81_RS26515	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KNZ81_RS26515	COG0072	phenylalanine-tRNA ligase activity
KNZ81_RS26540	COG0697	spore germination
KNZ81_RS26545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KNZ81_RS26575	COG2838	Isocitrate dehydrogenase
KNZ81_RS26620	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KNZ81_RS26625	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KNZ81_RS26630	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KNZ81_RS26635	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KNZ81_RS26640	COG1438	arginine binding
KNZ81_RS26645	COG4585	Histidine kinase
KNZ81_RS26650	COG2197	response regulator
KNZ81_RS26660	COG2409	Drug exporters of the RND superfamily
KNZ81_RS26665	COG0385	Bile acid
KNZ81_RS26675	COG0165	Argininosuccinate lyase
KNZ81_RS26695	COG0477	Major facilitator Superfamily
KNZ81_RS26700	COG0318	PFAM AMP-dependent synthetase and ligase
KNZ81_RS26700	COG0204	Acyl-transferase
KNZ81_RS26705	COG0584	glycerophosphoryl diester phosphodiesterase
KNZ81_RS26730	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KNZ81_RS26735	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KNZ81_RS26740	COG2011	ABC-type metal ion transport system permease component
KNZ81_RS26745	COG1464	Belongs to the NlpA lipoprotein family
KNZ81_RS26750	COG1464	Belongs to the NlpA lipoprotein family
KNZ81_RS26765	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
KNZ81_RS26770	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KNZ81_RS26770	COG1648	precorrin-2 dehydrogenase activity
KNZ81_RS26920	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KNZ81_RS26925	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KNZ81_RS26940	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KNZ81_RS26945	COG1560	Kdo2-lipid A biosynthetic process
KNZ81_RS26950	COG0438	transferase activity, transferring glycosyl groups
KNZ81_RS26960	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
KNZ81_RS26965	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KNZ81_RS26970	COG0217	transcriptional regulatory protein
KNZ81_RS26975	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
KNZ81_RS26980	COG0632	four-way junction helicase activity
KNZ81_RS26985	COG2255	four-way junction helicase activity
KNZ81_RS26995	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KNZ81_RS27000	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KNZ81_RS27005	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KNZ81_RS27010	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KNZ81_RS27020	COG1196	nuclear chromosome segregation
KNZ81_RS27025	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KNZ81_RS27035	COG0124	histidyl-tRNA synthetase
KNZ81_RS27050	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KNZ81_RS27065	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KNZ81_RS27070	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KNZ81_RS27075	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KNZ81_RS27080	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KNZ81_RS27085	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KNZ81_RS27090	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KNZ81_RS27095	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KNZ81_RS27105	COG0006	proline dipeptidase activity
KNZ81_RS27110	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KNZ81_RS27115	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KNZ81_RS27125	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KNZ81_RS27130	COG0540	Belongs to the ATCase OTCase family
KNZ81_RS27135	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KNZ81_RS27145	COG0505	Belongs to the CarA family
KNZ81_RS27150	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KNZ81_RS27155	COG0167	dihydroorotate dehydrogenase activity
KNZ81_RS27160	COG0284	orotidine-5'-phosphate decarboxylase activity
KNZ81_RS27175	COG1758	RNA polymerase activity
KNZ81_RS27185	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KNZ81_RS27200	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KNZ81_RS27215	COG2318	DinB family
KNZ81_RS27220	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KNZ81_RS27225	COG2390	Transcriptional regulator
KNZ81_RS27265	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KNZ81_RS27280	COG0583	DNA-binding transcription factor activity
KNZ81_RS27290	COG2233	PERMEase
KNZ81_RS27300	COG0738	Major facilitator superfamily
KNZ81_RS27305	COG1940	carbohydrate kinase activity
KNZ81_RS27305	COG1846	Transcriptional regulator
KNZ81_RS27310	COG1090	epimerase
KNZ81_RS27325	COG3201	nicotinamide mononucleotide transporter
KNZ81_RS27330	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KNZ81_RS27330	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KNZ81_RS27335	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KNZ81_RS27340	COG0140	phosphoribosyl-ATP diphosphatase activity
KNZ81_RS27345	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KNZ81_RS27375	COG1960	acyl-CoA dehydrogenase activity
KNZ81_RS27400	COG0463	Glycosyl transferase, family 2
KNZ81_RS27405	COG3030	protein affecting phage T7 exclusion by the F plasmid
KNZ81_RS27415	COG2270	Major facilitator Superfamily
KNZ81_RS27425	COG2364	Membrane
KNZ81_RS27430	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KNZ81_RS27515	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
KNZ81_RS27535	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KNZ81_RS27545	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KNZ81_RS27575	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KNZ81_RS27595	COG1716	ATPase activity
KNZ81_RS27615	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KNZ81_RS27625	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KNZ81_RS27625	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KNZ81_RS27675	COG0697	spore germination
KNZ81_RS27690	COG0697	spore germination
KNZ81_RS27710	COG4251	negative regulation of phosphorylation
KNZ81_RS27760	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KNZ81_RS27790	COG0815	Transfers the fatty acyl group on membrane lipoproteins
KNZ81_RS27815	COG1982	Orn Lys Arg decarboxylase major
KNZ81_RS27825	COG1968	undecaprenyl-diphosphatase activity
KNZ81_RS27845	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KNZ81_RS27865	COG0583	DNA-binding transcription factor activity
KNZ81_RS27905	COG0110	maltose O-acetyltransferase activity
KNZ81_RS27925	COG1832	CoA-binding protein
KNZ81_RS27930	COG1739	Uncharacterized protein family UPF0029
KNZ81_RS27945	COG0420	3'-5' exonuclease activity
KNZ81_RS27950	COG0419	ATPase involved in DNA repair
KNZ81_RS27955	COG1522	sequence-specific DNA binding
KNZ81_RS28020	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KNZ81_RS28045	COG1024	Enoyl-CoA hydratase
KNZ81_RS28050	COG0318	PFAM AMP-dependent synthetase and ligase
KNZ81_RS28085	COG0626	cystathionine gamma-synthase activity
KNZ81_RS28110	COG2188	Transcriptional regulator
KNZ81_RS28115	COG1940	carbohydrate kinase activity
KNZ81_RS28140	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KNZ81_RS28165	COG0488	(ABC) transporter
KNZ81_RS28170	COG0488	(ABC) transporter
KNZ81_RS28180	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KNZ81_RS28185	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KNZ81_RS28190	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KNZ81_RS28215	COG0791	NLP P60 protein
KNZ81_RS28215	COG1388	LysM domain
KNZ81_RS28215	COG3103	Sh3 type 3 domain protein
KNZ81_RS28220	COG0740	serine-type endopeptidase activity
KNZ81_RS28230	COG0831	urea catabolic process
KNZ81_RS28235	COG0832	Belongs to the urease beta subunit family
KNZ81_RS28240	COG0804	urea catabolic process
KNZ81_RS28250	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KNZ81_RS28255	COG0829	nickel cation binding
KNZ81_RS28260	COG0204	Acyl-transferase
KNZ81_RS28290	COG1132	(ABC) transporter
KNZ81_RS28305	COG2175	clavaminate synthase activity
KNZ81_RS28315	COG0435	Glutathione S-transferase
KNZ81_RS28335	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KNZ81_RS28340	COG0583	DNA-binding transcription factor activity
KNZ81_RS28345	COG2208	phosphoserine phosphatase activity
KNZ81_RS28345	COG2770	Histidine kinase
KNZ81_RS28360	COG0205	6-phosphofructokinase activity
KNZ81_RS28365	COG3442	glutamine amidotransferase
KNZ81_RS28375	COG0242	peptide deformylase activity
KNZ81_RS28385	COG1960	acyl-CoA dehydrogenase activity
KNZ81_RS28405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KNZ81_RS28430	COG1175	transmembrane transport
KNZ81_RS28435	COG0395	ABC-type sugar transport system, permease component
KNZ81_RS28440	COG2723	6-phospho-beta-galactosidase activity
KNZ81_RS28445	COG0501	Belongs to the peptidase M48B family
KNZ81_RS28480	COG4566	intracellular signal transduction
KNZ81_RS28485	COG4251	negative regulation of phosphorylation
KNZ81_RS28490	COG0784	Response regulator, receiver
KNZ81_RS28510	COG0656	L-ascorbic acid biosynthetic process
KNZ81_RS28520	COG1595	DNA-templated transcription, initiation
KNZ81_RS28525	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KNZ81_RS28530	COG1132	(ABC) transporter
KNZ81_RS28550	COG3693	PFAM glycoside hydrolase, family 10
KNZ81_RS28560	COG0181	hydroxymethylbilane synthase activity
KNZ81_RS28565	COG0181	hydroxymethylbilane synthase activity
KNZ81_RS28570	COG0113	porphobilinogen synthase activity
KNZ81_RS28655	COG3629	intracellular signal transduction
KNZ81_RS28655	COG3903	Transcriptional regulator
KNZ81_RS28675	COG0277	FAD linked oxidase domain protein
KNZ81_RS28685	COG0656	L-ascorbic acid biosynthetic process
KNZ81_RS28740	COG2234	aminopeptidase activity
KNZ81_RS28755	COG2226	methyltransferase
KNZ81_RS28765	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KNZ81_RS28780	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KNZ81_RS28910	COG0242	peptide deformylase activity
KNZ81_RS29020	COG0305	Participates in initiation and elongation during chromosome replication
KNZ81_RS29065	COG3328	transposase activity
KNZ81_RS29140	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KNZ81_RS29185	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KNZ81_RS29190	COG3279	Response regulator of the LytR AlgR family
KNZ81_RS29200	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KNZ81_RS29205	COG3275	phosphorelay sensor kinase activity
KNZ81_RS29270	COG0583	DNA-binding transcription factor activity
KNZ81_RS29280	COG1053	succinate dehydrogenase
KNZ81_RS29285	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KNZ81_RS29290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KNZ81_RS29300	COG3360	Dodecin
KNZ81_RS29305	COG2182	Extracellular solute-binding protein
KNZ81_RS29310	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
KNZ81_RS29315	COG0121	glutamine amidotransferase
KNZ81_RS29320	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KNZ81_RS29340	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KNZ81_RS29345	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KNZ81_RS29370	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KNZ81_RS29370	COG1796	DNA polymerase
KNZ81_RS29375	COG0142	geranyltranstransferase activity
KNZ81_RS29405	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
KNZ81_RS29425	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KNZ81_RS29435	COG0254	rRNA binding
KNZ81_RS29440	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KNZ81_RS29445	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KNZ81_RS29450	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KNZ81_RS29505	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KNZ81_RS29510	COG4948	Mandelate Racemase Muconate Lactonizing
KNZ81_RS29590	COG0464	growth
KNZ81_RS29605	COG3655	Transcriptional regulator
KNZ81_RS29615	COG0803	Belongs to the bacterial solute-binding protein 9 family
KNZ81_RS29625	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KNZ81_RS29630	COG1121	(ABC) transporter
KNZ81_RS29635	COG4608	Belongs to the ABC transporter superfamily
KNZ81_RS29645	COG0601	transmembrane transport
KNZ81_RS29650	COG0747	negative chemotaxis
KNZ81_RS29660	COG3458	cephalosporin-C deacetylase activity
KNZ81_RS29670	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KNZ81_RS29680	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
KNZ81_RS29685	COG0363	glucosamine-6-phosphate deaminase activity
KNZ81_RS29690	COG0590	tRNA wobble adenosine to inosine editing
KNZ81_RS29695	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KNZ81_RS29720	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KNZ81_RS29770	COG0745	RESPONSE REGULATOR receiver
KNZ81_RS29775	COG0243	molybdopterin cofactor binding
KNZ81_RS29780	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KNZ81_RS29785	COG2146	nitrite reductase [NAD(P)H] activity
KNZ81_RS29785	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KNZ81_RS29805	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
KNZ81_RS29810	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KNZ81_RS29815	COG1984	allophanate hydrolase subunit 2
KNZ81_RS29830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KNZ81_RS29840	COG1120	ATPase activity
KNZ81_RS29870	COG1132	(ABC) transporter
KNZ81_RS29875	COG1132	(ABC) transporter
KNZ81_RS29880	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KNZ81_RS29890	COG0110	maltose O-acetyltransferase activity
KNZ81_RS29930	COG0640	Transcriptional regulator
KNZ81_RS29940	COG1349	DNA-binding transcription factor activity
KNZ81_RS29955	COG3395	kinase activity
KNZ81_RS29960	COG0235	Class ii aldolase
KNZ81_RS29980	COG2124	cytochrome p450
KNZ81_RS29985	COG1174	glycine betaine transport
KNZ81_RS29990	COG1174	glycine betaine transport
KNZ81_RS30000	COG1125	glycine betaine transport
KNZ81_RS30000	COG0517	IMP dehydrogenase activity
KNZ81_RS30025	COG1960	acyl-CoA dehydrogenase activity
KNZ81_RS30030	COG1960	acyl-CoA dehydrogenase activity
KNZ81_RS30040	COG0601	transmembrane transport
KNZ81_RS30045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KNZ81_RS30050	COG0444	Belongs to the ABC transporter superfamily
KNZ81_RS30055	COG1124	(ABC) transporter
KNZ81_RS30100	COG1028	Short-chain dehydrogenase reductase Sdr
KNZ81_RS30110	COG0142	geranyltranstransferase activity
KNZ81_RS30145	COG3321	synthase
KNZ81_RS30145	COG0604	alcohol dehydrogenase
KNZ81_RS30160	COG3321	synthase
KNZ81_RS30160	COG0604	alcohol dehydrogenase
KNZ81_RS30175	COG3321	synthase
KNZ81_RS30175	COG0604	alcohol dehydrogenase
KNZ81_RS30200	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KNZ81_RS30235	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KNZ81_RS30245	COG1129	ABC transporter
KNZ81_RS30275	COG3483	tryptophan 2,3-dioxygenase activity
KNZ81_RS30280	COG1028	Short-chain dehydrogenase reductase Sdr
KNZ81_RS30285	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KNZ81_RS30290	COG2151	metal-sulfur cluster biosynthetic enzyme
KNZ81_RS30295	COG3396	Phenylacetate-CoA oxygenase
KNZ81_RS30305	COG3396	Phenylacetate-CoA oxygenase
KNZ81_RS30325	COG0604	alcohol dehydrogenase
KNZ81_RS30335	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KNZ81_RS30395	COG0515	serine threonine protein kinase
KNZ81_RS30430	COG1404	Belongs to the peptidase S8 family
KNZ81_RS30445	COG3246	L-lysine catabolic process to acetate
KNZ81_RS30450	COG1250	3-hydroxyacyl-CoA dehydrogenase
KNZ81_RS30475	COG1309	transcriptional regulator
KNZ81_RS30490	COG1028	Short-chain dehydrogenase reductase Sdr
KNZ81_RS30495	COG1309	transcriptional regulator
KNZ81_RS30510	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KNZ81_RS30525	COG1250	3-hydroxyacyl-CoA dehydrogenase
KNZ81_RS30530	COG0604	alcohol dehydrogenase
KNZ81_RS30540	COG0789	Transcriptional regulator
KNZ81_RS30545	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KNZ81_RS30605	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KNZ81_RS30625	COG1028	Short-chain dehydrogenase reductase Sdr
KNZ81_RS30665	COG3629	intracellular signal transduction
KNZ81_RS30725	COG3321	synthase
KNZ81_RS30725	COG0604	alcohol dehydrogenase
KNZ81_RS30735	COG0477	Major facilitator Superfamily
KNZ81_RS30745	COG3629	intracellular signal transduction
KNZ81_RS30750	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KNZ81_RS30760	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KNZ81_RS30780	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KNZ81_RS30790	COG1012	belongs to the aldehyde dehydrogenase family
KNZ81_RS30825	COG2814	Major facilitator Superfamily
KNZ81_RS30885	COG4106	trans-aconitate 2-methyltransferase activity
KNZ81_RS30925	COG1028	Short-chain dehydrogenase reductase Sdr
KNZ81_RS30930	COG1028	Short-chain dehydrogenase reductase Sdr
KNZ81_RS30935	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KNZ81_RS30940	COG0066	3-isopropylmalate dehydratase activity
KNZ81_RS30945	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KNZ81_RS30960	COG5002	protein histidine kinase activity
KNZ81_RS30965	COG0745	RESPONSE REGULATOR receiver
KNZ81_RS30980	COG1136	(ABC) transporter
KNZ81_RS30985	COG0577	efflux transmembrane transporter activity
KNZ81_RS31025	COG0745	RESPONSE REGULATOR receiver
KNZ81_RS31030	COG2205	protein histidine kinase activity