locus-tag	class	description
EJC51_RS00205	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EJC51_RS00215	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EJC51_RS00245	COG3285	dna ligase
EJC51_RS00245	COG1793	dna ligase
EJC51_RS00325	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EJC51_RS00440	COG1011	Hydrolase
EJC51_RS00560	COG3903	Transcriptional regulator
EJC51_RS00560	COG3629	intracellular signal transduction
EJC51_RS00585	COG0745	RESPONSE REGULATOR receiver
EJC51_RS00595	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EJC51_RS00605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EJC51_RS00610	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EJC51_RS00625	COG0183	Belongs to the thiolase family
EJC51_RS00630	COG0318	PFAM AMP-dependent synthetase and ligase
EJC51_RS00650	COG1172	Belongs to the binding-protein-dependent transport system permease family
EJC51_RS00655	COG1129	ABC transporter
EJC51_RS00680	COG1063	alcohol dehydrogenase
EJC51_RS00705	COG4585	Histidine kinase
EJC51_RS00710	COG2197	response regulator
EJC51_RS00720	COG2801	Transposase and inactivated derivatives
EJC51_RS00720	COG3415	Transposase
EJC51_RS00730	COG3250	beta-galactosidase activity
EJC51_RS00750	COG1609	Transcriptional regulator
EJC51_RS00810	COG2267	carboxylic ester hydrolase activity
EJC51_RS00840	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EJC51_RS00845	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
EJC51_RS00850	COG1937	Protein conserved in bacteria
EJC51_RS00855	COG0730	response to heat
EJC51_RS00860	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EJC51_RS00865	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EJC51_RS00865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EJC51_RS00880	COG0318	PFAM AMP-dependent synthetase and ligase
EJC51_RS00960	COG1309	transcriptional regulator
EJC51_RS00965	COG1028	Short-chain dehydrogenase reductase Sdr
EJC51_RS01005	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EJC51_RS01035	COG0259	pyridoxamine-phosphate oxidase activity
EJC51_RS01050	COG3433	isochorismatase activity
EJC51_RS01050	COG1535	isochorismatase
EJC51_RS01060	COG1021	2,3-dihydroxybenzoate-AMP ligase
EJC51_RS01145	COG2755	lipolytic protein G-D-S-L family
EJC51_RS01165	COG0789	Transcriptional regulator
EJC51_RS01170	COG4221	oxidoreductase activity
EJC51_RS01200	COG2124	cytochrome p450
EJC51_RS01275	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EJC51_RS01345	COG1131	(ABC) transporter
EJC51_RS01385	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
EJC51_RS01385	COG1672	PFAM Archaeal ATPase
EJC51_RS01415	COG1028	Short-chain dehydrogenase reductase Sdr
EJC51_RS01425	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EJC51_RS01435	COG0318	PFAM AMP-dependent synthetase and ligase
EJC51_RS01445	COG2267	carboxylic ester hydrolase activity
EJC51_RS01485	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EJC51_RS01500	COG1764	response to oxidative stress
EJC51_RS01575	COG0477	Major facilitator Superfamily
EJC51_RS01600	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EJC51_RS01615	COG1012	belongs to the aldehyde dehydrogenase family
EJC51_RS01630	COG1595	DNA-templated transcription, initiation
EJC51_RS01635	COG1053	succinate dehydrogenase
EJC51_RS01640	COG1595	DNA-templated transcription, initiation
EJC51_RS01670	COG0657	acetylesterase activity
EJC51_RS01695	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
EJC51_RS01710	COG1595	DNA-templated transcription, initiation
EJC51_RS01790	COG2249	NAD(P)H dehydrogenase (quinone) activity
EJC51_RS01795	COG0667	Aldo Keto reductase
EJC51_RS01805	COG4221	oxidoreductase activity
EJC51_RS01875	COG1619	proteins homologs of microcin C7 resistance protein MccF
EJC51_RS01895	COG0583	DNA-binding transcription factor activity
EJC51_RS01915	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EJC51_RS01920	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
EJC51_RS01925	COG2080	2 iron, 2 sulfur cluster binding
EJC51_RS01940	COG1028	Short-chain dehydrogenase reductase Sdr
EJC51_RS01960	COG1063	alcohol dehydrogenase
EJC51_RS02000	COG0655	NAD(P)H dehydrogenase (quinone) activity
EJC51_RS02010	COG1063	alcohol dehydrogenase
EJC51_RS02035	COG1028	Short-chain dehydrogenase reductase Sdr
EJC51_RS02065	COG0477	Major facilitator Superfamily
EJC51_RS02085	COG3852	Histidine kinase
EJC51_RS02095	COG1028	Short-chain dehydrogenase reductase Sdr
EJC51_RS02110	COG1028	Short-chain dehydrogenase reductase Sdr
EJC51_RS02135	COG1063	alcohol dehydrogenase
EJC51_RS02155	COG5520	Belongs to the glycosyl hydrolase 30 family
EJC51_RS02170	COG2207	Transcriptional regulator
EJC51_RS02170	COG3708	Transcriptional regulator
EJC51_RS02215	COG3903	Transcriptional regulator
EJC51_RS02215	COG3629	intracellular signal transduction
EJC51_RS02255	COG0300	oxidoreductase activity
EJC51_RS02300	COG1028	Short-chain dehydrogenase reductase Sdr
EJC51_RS02330	COG1309	transcriptional regulator
EJC51_RS02340	COG1309	transcriptional regulator
EJC51_RS02345	COG1902	pentaerythritol trinitrate reductase activity
EJC51_RS02360	COG3321	synthase
EJC51_RS02360	COG0604	alcohol dehydrogenase
EJC51_RS02370	COG1028	Short-chain dehydrogenase reductase Sdr
EJC51_RS02375	COG1960	acyl-CoA dehydrogenase activity
EJC51_RS02390	COG1028	Short-chain dehydrogenase reductase Sdr
EJC51_RS02395	COG1309	transcriptional regulator
EJC51_RS02400	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EJC51_RS02415	COG1028	Short-chain dehydrogenase reductase Sdr
EJC51_RS02425	COG1024	Enoyl-CoA hydratase
EJC51_RS02425	COG1250	3-hydroxyacyl-CoA dehydrogenase
EJC51_RS02435	COG0318	PFAM AMP-dependent synthetase and ligase
EJC51_RS02485	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
EJC51_RS02490	COG1309	transcriptional regulator
EJC51_RS02500	COG1012	belongs to the aldehyde dehydrogenase family
EJC51_RS02505	COG1902	pentaerythritol trinitrate reductase activity
EJC51_RS02520	COG0477	Major facilitator Superfamily
EJC51_RS02625	COG0596	Alpha beta hydrolase
EJC51_RS02715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EJC51_RS02735	COG2814	Major facilitator Superfamily
EJC51_RS02760	COG3507	Belongs to the glycosyl hydrolase 43 family
EJC51_RS02790	COG1309	transcriptional regulator
EJC51_RS02805	COG1280	lysine exporter protein (LysE YggA)
EJC51_RS02820	COG2124	cytochrome p450
EJC51_RS02825	COG1028	Short-chain dehydrogenase reductase Sdr
EJC51_RS02865	COG2249	NAD(P)H dehydrogenase (quinone) activity
EJC51_RS02870	COG0640	Transcriptional regulator
EJC51_RS02875	COG4585	Histidine kinase
EJC51_RS02895	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EJC51_RS02920	COG2072	flavoprotein involved in K transport
EJC51_RS02935	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EJC51_RS02955	COG2272	Belongs to the type-B carboxylesterase lipase family
EJC51_RS02965	COG0515	serine threonine protein kinase
EJC51_RS02965	COG2815	serine threonine protein kinase
EJC51_RS02975	COG0494	nUDIX hydrolase
EJC51_RS02990	COG1120	ATPase activity
EJC51_RS02995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EJC51_RS03060	COG1116	anion transmembrane transporter activity
EJC51_RS03065	COG0640	Transcriptional regulator
EJC51_RS03070	COG0598	Magnesium transport protein CorA
EJC51_RS03075	COG0598	Magnesium transport protein CorA
EJC51_RS03080	COG0598	Magnesium transport protein CorA
EJC51_RS03115	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EJC51_RS03120	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EJC51_RS03125	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EJC51_RS03135	COG0531	amino acid
EJC51_RS03210	COG0583	DNA-binding transcription factor activity
EJC51_RS03220	COG0745	RESPONSE REGULATOR receiver
EJC51_RS03235	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EJC51_RS03250	COG0300	oxidoreductase activity
EJC51_RS03255	COG0477	Major facilitator Superfamily
EJC51_RS03260	COG1733	regulation of RNA biosynthetic process
EJC51_RS03285	COG0477	Major facilitator Superfamily
EJC51_RS03295	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EJC51_RS03315	COG2867	negative regulation of translational initiation
EJC51_RS03320	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EJC51_RS03335	COG0662	Cupin 2, conserved barrel domain protein
EJC51_RS03395	COG0477	Major facilitator Superfamily
EJC51_RS03400	COG3387	PFAM Glycoside hydrolase 15-related
EJC51_RS03415	COG0121	glutamine amidotransferase
EJC51_RS03495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EJC51_RS03510	COG0800	Aldolase
EJC51_RS03515	COG1028	Short-chain dehydrogenase reductase Sdr
EJC51_RS03520	COG1063	alcohol dehydrogenase
EJC51_RS03530	COG3618	amidohydrolase
EJC51_RS03535	COG4948	Mandelate Racemase Muconate Lactonizing
EJC51_RS03540	COG1172	Belongs to the binding-protein-dependent transport system permease family
EJC51_RS03545	COG1129	ABC transporter
EJC51_RS03570	COG3693	PFAM glycoside hydrolase, family 10
EJC51_RS03585	COG2828	Protein conserved in bacteria
EJC51_RS03620	COG3345	alpha-galactosidase
EJC51_RS03640	COG0667	Aldo Keto reductase
EJC51_RS03670	COG1733	regulation of RNA biosynthetic process
EJC51_RS03680	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EJC51_RS03700	COG4585	Histidine kinase
EJC51_RS03705	COG2197	response regulator
EJC51_RS03735	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EJC51_RS03745	COG1309	transcriptional regulator
EJC51_RS03765	COG2205	protein histidine kinase activity
EJC51_RS03775	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EJC51_RS03785	COG1181	Belongs to the D-alanine--D-alanine ligase family
EJC51_RS03790	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
EJC51_RS03795	COG0583	DNA-binding transcription factor activity
EJC51_RS03820	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EJC51_RS03825	COG0254	rRNA binding
EJC51_RS03830	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EJC51_RS03845	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EJC51_RS03875	COG0583	DNA-binding transcription factor activity
EJC51_RS03935	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
EJC51_RS03960	COG0513	Belongs to the DEAD box helicase family
EJC51_RS03980	COG2409	Drug exporters of the RND superfamily
EJC51_RS03985	COG4585	Histidine kinase
EJC51_RS03990	COG2197	response regulator
EJC51_RS03995	COG1609	Transcriptional regulator
EJC51_RS04000	COG4209	transmembrane transport
EJC51_RS04005	COG0395	ABC-type sugar transport system, permease component
EJC51_RS04040	COG3795	YCII-related domain
EJC51_RS04045	COG4941	Belongs to the sigma-70 factor family
EJC51_RS04055	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EJC51_RS04070	COG4977	sequence-specific DNA binding
EJC51_RS04080	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EJC51_RS04085	COG0318	PFAM AMP-dependent synthetase and ligase
EJC51_RS04090	COG3321	synthase
EJC51_RS04090	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EJC51_RS04140	COG0745	RESPONSE REGULATOR receiver
EJC51_RS04145	COG2205	protein histidine kinase activity
EJC51_RS04160	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EJC51_RS04165	COG0583	DNA-binding transcription factor activity
EJC51_RS04195	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EJC51_RS04210	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EJC51_RS04250	COG0657	acetylesterase activity
EJC51_RS04270	COG0596	Alpha beta hydrolase
EJC51_RS04290	COG2226	methyltransferase
EJC51_RS04315	COG1846	Transcriptional regulator
EJC51_RS04320	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EJC51_RS04325	COG2045	Belongs to the ComB family
EJC51_RS04345	COG0789	Transcriptional regulator
EJC51_RS04350	COG2226	methyltransferase
EJC51_RS04355	COG0456	acetyltransferase
EJC51_RS04360	COG0574	Belongs to the PEP-utilizing enzyme family
EJC51_RS04360	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EJC51_RS04380	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
EJC51_RS04400	COG0543	2 iron, 2 sulfur cluster binding
EJC51_RS04415	COG0517	IMP dehydrogenase activity
EJC51_RS04415	COG0516	GMP reductase activity
EJC51_RS04425	COG0309	Hydrogenase expression formation protein (HypE)
EJC51_RS04480	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
EJC51_RS04500	COG1269	ATP hydrolysis coupled proton transport
EJC51_RS04520	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EJC51_RS04525	COG0569	domain protein
EJC51_RS04535	COG3842	ATPase activity
EJC51_RS04570	COG1131	(ABC) transporter
EJC51_RS04575	COG1830	Aldolase
EJC51_RS04585	COG0517	IMP dehydrogenase activity
EJC51_RS04600	COG2920	part of a sulfur-relay system
EJC51_RS04605	COG1252	NADH dehydrogenase
EJC51_RS04640	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EJC51_RS04645	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EJC51_RS04650	COG1063	alcohol dehydrogenase
EJC51_RS04670	COG0045	succinate-CoA ligase (ADP-forming) activity
EJC51_RS04670	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EJC51_RS04670	COG1042	CoA-binding domain protein
EJC51_RS04705	COG0549	Belongs to the carbamate kinase family
EJC51_RS04725	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EJC51_RS04745	COG1131	(ABC) transporter
EJC51_RS04770	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EJC51_RS04795	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EJC51_RS04810	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EJC51_RS04815	COG0674	pyruvate-flavodoxin oxidoreductase activity
EJC51_RS04820	COG1013	pyruvate-flavodoxin oxidoreductase activity
EJC51_RS04825	COG0493	'glutamate synthase
EJC51_RS04835	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EJC51_RS04855	COG1028	Short-chain dehydrogenase reductase Sdr
EJC51_RS04865	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EJC51_RS04875	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EJC51_RS04880	COG4948	Mandelate Racemase Muconate Lactonizing
EJC51_RS04900	COG0601	transmembrane transport
EJC51_RS04905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EJC51_RS04935	COG0135	phosphoribosylanthranilate isomerase activity
EJC51_RS04960	COG4044	May play a role in the intracellular transport of hydrophobic ligands
EJC51_RS04985	COG2353	YceI-like domain
EJC51_RS04995	COG2326	polyphosphate kinase activity
EJC51_RS05010	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EJC51_RS05010	COG1017	nitric oxide dioxygenase activity
EJC51_RS05015	COG4191	Histidine kinase
EJC51_RS05060	COG4106	trans-aconitate 2-methyltransferase activity
EJC51_RS05120	COG1846	Transcriptional regulator
EJC51_RS05130	COG2813	Specifically methylates the guanine in position
EJC51_RS05155	COG2409	Drug exporters of the RND superfamily
EJC51_RS05180	COG1136	(ABC) transporter
EJC51_RS05185	COG4585	Histidine kinase
EJC51_RS05190	COG2197	response regulator
EJC51_RS05195	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EJC51_RS05205	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EJC51_RS05205	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EJC51_RS05230	COG1653	transport
EJC51_RS05280	COG2267	carboxylic ester hydrolase activity
EJC51_RS05305	COG0009	L-threonylcarbamoyladenylate synthase
EJC51_RS05330	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EJC51_RS05340	COG3300	MHYT domain
EJC51_RS05340	COG5001	Diguanylate cyclase
EJC51_RS05360	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EJC51_RS05365	COG1621	beta-fructofuranosidase activity
EJC51_RS05375	COG1175	transmembrane transport
EJC51_RS05380	COG0395	ABC-type sugar transport system, permease component
EJC51_RS05390	COG1609	Transcriptional regulator
EJC51_RS05425	COG2207	Transcriptional regulator
EJC51_RS05430	COG2223	nitrite transmembrane transporter activity
EJC51_RS05455	COG1028	Short-chain dehydrogenase reductase Sdr
EJC51_RS05460	COG1793	dna ligase
EJC51_RS05475	COG0181	hydroxymethylbilane synthase activity
EJC51_RS05485	COG0842	Transport permease protein
EJC51_RS05495	COG1846	Transcriptional regulator
EJC51_RS05500	COG1191	sigma factor activity
EJC51_RS05530	COG0366	Alpha amylase catalytic
EJC51_RS05540	COG3281	Trehalose synthase
EJC51_RS05545	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EJC51_RS05550	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
EJC51_RS05565	COG1252	NADH dehydrogenase
EJC51_RS05595	COG1982	Orn Lys Arg decarboxylase major
EJC51_RS05605	COG0477	Major facilitator Superfamily
EJC51_RS05635	COG5002	protein histidine kinase activity
EJC51_RS05675	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EJC51_RS05695	COG0492	ferredoxin-NADP+ reductase activity
EJC51_RS05700	COG3852	Histidine kinase
EJC51_RS05710	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
EJC51_RS05710	COG1672	PFAM Archaeal ATPase
EJC51_RS05725	COG3345	alpha-galactosidase
EJC51_RS05730	COG1846	Transcriptional regulator
EJC51_RS05730	COG1940	carbohydrate kinase activity
EJC51_RS05745	COG2340	Cysteine-rich secretory protein family
EJC51_RS05765	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EJC51_RS05770	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EJC51_RS05770	COG0515	serine threonine protein kinase
EJC51_RS05780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EJC51_RS05795	COG3647	Membrane
EJC51_RS05805	COG0667	Aldo Keto reductase
EJC51_RS05835	COG2304	oxidoreductase activity
EJC51_RS05840	COG0328	RNA-DNA hybrid ribonuclease activity
EJC51_RS05855	COG1609	Transcriptional regulator
EJC51_RS05870	COG2205	protein histidine kinase activity
EJC51_RS05870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EJC51_RS05885	COG0596	Alpha beta hydrolase
EJC51_RS05890	COG0740	serine-type endopeptidase activity
EJC51_RS05895	COG0740	serine-type endopeptidase activity
EJC51_RS05910	COG1191	sigma factor activity
EJC51_RS05940	COG1131	(ABC) transporter
EJC51_RS05940	COG1716	ATPase activity
EJC51_RS05940	COG0842	Transport permease protein
EJC51_RS05960	COG0667	Aldo Keto reductase
EJC51_RS05965	COG0583	DNA-binding transcription factor activity
EJC51_RS05980	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EJC51_RS05985	COG0346	lactoylglutathione lyase activity
EJC51_RS06000	COG0667	Aldo Keto reductase
EJC51_RS06005	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
EJC51_RS06010	COG1012	belongs to the aldehyde dehydrogenase family
EJC51_RS06050	COG4941	Belongs to the sigma-70 factor family
EJC51_RS06075	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EJC51_RS06085	COG0431	NADPH-dependent FMN reductase
EJC51_RS06105	COG0583	DNA-binding transcription factor activity
EJC51_RS06115	COG0702	epimerase
EJC51_RS06140	COG0640	Transcriptional regulator
EJC51_RS06215	COG2235	arginine
EJC51_RS06270	COG1672	PFAM Archaeal ATPase
EJC51_RS06270	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
EJC51_RS06305	COG1024	Enoyl-CoA hydratase
EJC51_RS06325	COG0596	Alpha beta hydrolase
EJC51_RS06340	COG0318	PFAM AMP-dependent synthetase and ligase
EJC51_RS06345	COG2366	antibiotic biosynthetic process
EJC51_RS06395	COG2070	2-Nitropropane dioxygenase
EJC51_RS06400	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EJC51_RS06425	COG0515	serine threonine protein kinase
EJC51_RS06425	COG2815	serine threonine protein kinase
EJC51_RS06445	COG1509	lysine 2,3-aminomutase activity
EJC51_RS06450	COG1960	acyl-CoA dehydrogenase activity
EJC51_RS06495	COG2376	Dihydroxyacetone kinase
EJC51_RS06500	COG1461	Dihydroxyacetone kinase
EJC51_RS06505	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
EJC51_RS06515	COG1028	Short-chain dehydrogenase reductase Sdr
EJC51_RS06540	COG1902	pentaerythritol trinitrate reductase activity
EJC51_RS06540	COG0446	pyridine nucleotide-disulphide oxidoreductase
EJC51_RS06565	COG2890	protein-(glutamine-N5) methyltransferase activity
EJC51_RS06585	COG1028	Short-chain dehydrogenase reductase Sdr
EJC51_RS06585	COG0604	alcohol dehydrogenase
EJC51_RS06585	COG3321	synthase
EJC51_RS06590	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EJC51_RS06610	COG3458	cephalosporin-C deacetylase activity
EJC51_RS06615	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EJC51_RS06625	COG2226	methyltransferase
EJC51_RS06640	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EJC51_RS06645	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EJC51_RS06650	COG1686	Belongs to the peptidase S11 family
EJC51_RS06665	COG2066	Belongs to the glutaminase family
EJC51_RS06680	COG1113	amino acid transport
EJC51_RS06685	COG2186	Transcriptional regulator
EJC51_RS06690	COG1968	undecaprenyl-diphosphatase activity
EJC51_RS06695	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EJC51_RS06700	COG1993	acr, cog1993
EJC51_RS06705	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EJC51_RS06735	COG1175	transmembrane transport
EJC51_RS06740	COG0395	ABC-type sugar transport system, permease component
EJC51_RS06770	COG1960	acyl-CoA dehydrogenase activity
EJC51_RS06780	COG3340	Belongs to the peptidase S51 family
EJC51_RS06800	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EJC51_RS06800	COG2010	Cytochrome c
EJC51_RS06805	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EJC51_RS06890	COG1215	transferase activity, transferring glycosyl groups
EJC51_RS06945	COG1088	dTDP-glucose 4,6-dehydratase activity
EJC51_RS06955	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EJC51_RS06985	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EJC51_RS07055	COG1028	Short-chain dehydrogenase reductase Sdr
EJC51_RS07080	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EJC51_RS07085	COG1215	transferase activity, transferring glycosyl groups
EJC51_RS07120	COG1349	DNA-binding transcription factor activity
EJC51_RS07145	COG1760	l-serine dehydratase
EJC51_RS07150	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EJC51_RS07160	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EJC51_RS07180	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EJC51_RS07195	COG4176	ABC-type proline glycine betaine transport system permease component
EJC51_RS07200	COG4175	Glycine betaine
EJC51_RS07200	COG0517	IMP dehydrogenase activity
EJC51_RS07205	COG1012	belongs to the aldehyde dehydrogenase family
EJC51_RS07220	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
EJC51_RS07235	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EJC51_RS07255	COG0577	efflux transmembrane transporter activity
EJC51_RS07260	COG1136	(ABC) transporter
EJC51_RS07290	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EJC51_RS07305	COG1028	Short-chain dehydrogenase reductase Sdr
EJC51_RS07315	COG1940	carbohydrate kinase activity
EJC51_RS07325	COG2813	Specifically methylates the guanine in position
EJC51_RS07330	COG0191	fructose-bisphosphate aldolase activity
EJC51_RS07335	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EJC51_RS07340	COG1349	DNA-binding transcription factor activity
EJC51_RS07345	COG3387	PFAM Glycoside hydrolase 15-related
EJC51_RS07355	COG2382	esterase
EJC51_RS07360	COG1132	(ABC) transporter
EJC51_RS07370	COG1132	(ABC) transporter
EJC51_RS07380	COG1120	ATPase activity
EJC51_RS07385	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EJC51_RS07390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EJC51_RS07395	COG3486	L-lysine 6-monooxygenase (NADPH) activity
EJC51_RS07450	COG2197	response regulator
EJC51_RS07455	COG3594	Acyltransferase
EJC51_RS07480	COG3321	synthase
EJC51_RS07480	COG0604	alcohol dehydrogenase
EJC51_RS07505	COG3284	Transcriptional regulator
EJC51_RS07525	COG0725	ABC transporter, periplasmic molybdate-binding protein
EJC51_RS07545	COG0142	geranyltranstransferase activity
EJC51_RS07560	COG0346	lactoylglutathione lyase activity
EJC51_RS07565	COG2226	methyltransferase
EJC51_RS07570	COG2223	nitrite transmembrane transporter activity
EJC51_RS07590	COG2197	response regulator
EJC51_RS07595	COG4585	Histidine kinase
EJC51_RS07600	COG2409	Drug exporters of the RND superfamily
EJC51_RS07605	COG3903	Transcriptional regulator
EJC51_RS07605	COG3629	intracellular signal transduction
EJC51_RS07620	COG0445	tRNA wobble uridine modification
EJC51_RS07635	COG1660	Displays ATPase and GTPase activities
EJC51_RS07645	COG1090	epimerase
EJC51_RS07650	COG3345	alpha-galactosidase
EJC51_RS07670	COG0515	serine threonine protein kinase
EJC51_RS07685	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EJC51_RS07750	COG0584	glycerophosphoryl diester phosphodiesterase
EJC51_RS07770	COG0667	Aldo Keto reductase
EJC51_RS07795	COG0671	phosphoesterase, PA-phosphatase related
EJC51_RS07805	COG1309	transcriptional regulator
EJC51_RS07830	COG2233	PERMEase
EJC51_RS07835	COG0640	Transcriptional regulator
EJC51_RS07840	COG1902	pentaerythritol trinitrate reductase activity
EJC51_RS07845	COG3509	depolymerase
EJC51_RS07860	COG1960	acyl-CoA dehydrogenase activity
EJC51_RS07880	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EJC51_RS07885	COG2971	BadF BadG BcrA BcrD
EJC51_RS07895	COG2706	6-phosphogluconolactonase activity
EJC51_RS07910	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EJC51_RS07920	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
EJC51_RS07920	COG1672	PFAM Archaeal ATPase
EJC51_RS07925	COG1028	Short-chain dehydrogenase reductase Sdr
EJC51_RS07965	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EJC51_RS07970	COG2124	cytochrome p450
EJC51_RS08000	COG4221	oxidoreductase activity
EJC51_RS08005	COG0477	Major facilitator Superfamily
EJC51_RS08020	COG2205	protein histidine kinase activity
EJC51_RS08025	COG0745	RESPONSE REGULATOR receiver
EJC51_RS08040	COG0659	secondary active sulfate transmembrane transporter activity
EJC51_RS08050	COG0697	spore germination
EJC51_RS08060	COG0432	Pfam Uncharacterised protein family UPF0047
EJC51_RS08065	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EJC51_RS08070	COG1116	anion transmembrane transporter activity
EJC51_RS08090	COG1132	(ABC) transporter
EJC51_RS08095	COG1846	Transcriptional regulator
EJC51_RS08100	COG1301	dicarboxylic acid transport
EJC51_RS08115	COG1132	(ABC) transporter
EJC51_RS08120	COG1132	(ABC) transporter
EJC51_RS08145	COG0254	rRNA binding
EJC51_RS08160	COG1946	Acyl-CoA thioesterase
EJC51_RS08170	COG2018	Roadblock/LC7 domain
EJC51_RS08240	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EJC51_RS08260	COG2115	Belongs to the xylose isomerase family
EJC51_RS08290	COG1012	belongs to the aldehyde dehydrogenase family
EJC51_RS08300	COG0326	Molecular chaperone. Has ATPase activity
EJC51_RS08320	COG2814	Major facilitator Superfamily
EJC51_RS08340	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EJC51_RS08355	COG0179	Fumarylacetoacetate (FAA) hydrolase
EJC51_RS08395	COG1846	Transcriptional regulator
EJC51_RS08425	COG1960	acyl-CoA dehydrogenase activity
EJC51_RS08430	COG1960	acyl-CoA dehydrogenase activity
EJC51_RS08445	COG0492	ferredoxin-NADP+ reductase activity
EJC51_RS08450	COG1793	dna ligase
EJC51_RS08460	COG1012	belongs to the aldehyde dehydrogenase family
EJC51_RS08470	COG3424	synthase
EJC51_RS08475	COG2124	cytochrome p450
EJC51_RS08485	COG1960	acyl-CoA dehydrogenase activity
EJC51_RS08495	COG0242	peptide deformylase activity
EJC51_RS08505	COG3442	glutamine amidotransferase
EJC51_RS08510	COG0205	6-phosphofructokinase activity
EJC51_RS08535	COG3275	phosphorelay sensor kinase activity
EJC51_RS08540	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EJC51_RS08550	COG3279	Response regulator of the LytR AlgR family
EJC51_RS08555	COG1522	sequence-specific DNA binding
EJC51_RS08560	COG1834	amidinotransferase
EJC51_RS08565	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EJC51_RS08585	COG0829	nickel cation binding
EJC51_RS08590	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
EJC51_RS08600	COG0804	urea catabolic process
EJC51_RS08605	COG0832	Belongs to the urease beta subunit family
EJC51_RS08610	COG0831	urea catabolic process
EJC51_RS08615	COG1309	transcriptional regulator
EJC51_RS08630	COG0740	serine-type endopeptidase activity
EJC51_RS08660	COG0156	8-amino-7-oxononanoate synthase activity
EJC51_RS08665	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EJC51_RS08670	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EJC51_RS08675	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EJC51_RS08700	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EJC51_RS08715	COG1136	(ABC) transporter
EJC51_RS08720	COG1136	(ABC) transporter
EJC51_RS08720	COG0577	efflux transmembrane transporter activity
EJC51_RS08725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EJC51_RS08750	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EJC51_RS08755	COG3663	DNA glycosylase
EJC51_RS08775	COG4585	Histidine kinase
EJC51_RS08780	COG2197	response regulator
EJC51_RS08785	COG1940	carbohydrate kinase activity
EJC51_RS08790	COG2188	Transcriptional regulator
EJC51_RS08795	COG1595	DNA-templated transcription, initiation
EJC51_RS08800	COG2267	carboxylic ester hydrolase activity
EJC51_RS08810	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EJC51_RS08835	COG0626	cystathionine gamma-synthase activity
EJC51_RS08850	COG1028	Short-chain dehydrogenase reductase Sdr
EJC51_RS08865	COG1522	sequence-specific DNA binding
EJC51_RS08870	COG0419	ATPase involved in DNA repair
EJC51_RS08875	COG0420	3'-5' exonuclease activity
EJC51_RS08880	COG1739	Uncharacterized protein family UPF0029
EJC51_RS08900	COG1832	CoA-binding protein
EJC51_RS08955	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EJC51_RS09005	COG0640	Transcriptional regulator
EJC51_RS09030	COG0110	maltose O-acetyltransferase activity
EJC51_RS09080	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EJC51_RS09095	COG0183	Belongs to the thiolase family
EJC51_RS09125	COG1968	undecaprenyl-diphosphatase activity
EJC51_RS09140	COG3896	Chloramphenicol phosphotransferase-like protein
EJC51_RS09150	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EJC51_RS09160	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EJC51_RS09185	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EJC51_RS09230	COG0583	DNA-binding transcription factor activity
EJC51_RS09235	COG0697	spore germination
EJC51_RS09290	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
EJC51_RS09295	COG0384	phenazine biosynthesis protein PhzF
EJC51_RS09325	COG1609	Transcriptional regulator
EJC51_RS09335	COG0395	ABC-type sugar transport system, permease component
EJC51_RS09340	COG1175	transmembrane transport
EJC51_RS09350	COG3507	Belongs to the glycosyl hydrolase 43 family
EJC51_RS09360	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EJC51_RS09365	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EJC51_RS09370	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EJC51_RS09400	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EJC51_RS09400	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EJC51_RS09430	COG1716	ATPase activity
EJC51_RS09450	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EJC51_RS09480	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EJC51_RS09490	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EJC51_RS09505	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
EJC51_RS09515	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EJC51_RS09525	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EJC51_RS09530	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EJC51_RS09580	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EJC51_RS09585	COG2814	Major facilitator Superfamily
EJC51_RS09590	COG4336	lyase activity
EJC51_RS09595	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EJC51_RS09600	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EJC51_RS09605	COG1984	allophanate hydrolase subunit 2
EJC51_RS09610	COG2755	lipolytic protein G-D-S-L family
EJC51_RS09615	COG0438	transferase activity, transferring glycosyl groups
EJC51_RS09650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EJC51_RS09655	COG2364	Membrane
EJC51_RS09665	COG2270	Major facilitator Superfamily
EJC51_RS09680	COG0463	Glycosyl transferase, family 2
EJC51_RS09715	COG1960	acyl-CoA dehydrogenase activity
EJC51_RS09765	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EJC51_RS09770	COG0140	phosphoribosyl-ATP diphosphatase activity
EJC51_RS09775	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EJC51_RS09780	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EJC51_RS09780	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EJC51_RS09785	COG3201	nicotinamide mononucleotide transporter
EJC51_RS09795	COG1940	carbohydrate kinase activity
EJC51_RS09795	COG1846	Transcriptional regulator
EJC51_RS09810	COG2233	PERMEase
EJC51_RS09835	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EJC51_RS09850	COG3842	ATPase activity
EJC51_RS09870	COG2188	Transcriptional regulator
EJC51_RS09880	COG0531	amino acid
EJC51_RS09900	COG2390	Transcriptional regulator
EJC51_RS09905	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EJC51_RS09910	COG2409	Drug exporters of the RND superfamily
EJC51_RS09920	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EJC51_RS09935	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EJC51_RS09950	COG0194	GDP metabolic process
EJC51_RS09960	COG0284	orotidine-5'-phosphate decarboxylase activity
EJC51_RS09965	COG0167	dihydroorotate dehydrogenase activity
EJC51_RS09970	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EJC51_RS09975	COG0505	Belongs to the CarA family
EJC51_RS09985	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EJC51_RS09990	COG0540	Belongs to the ATCase OTCase family
EJC51_RS09995	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EJC51_RS10005	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EJC51_RS10010	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EJC51_RS10015	COG0006	proline dipeptidase activity
EJC51_RS10025	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EJC51_RS10030	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EJC51_RS10035	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EJC51_RS10040	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EJC51_RS10045	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EJC51_RS10055	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EJC51_RS10060	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EJC51_RS10080	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EJC51_RS10105	COG0124	histidyl-tRNA synthetase
EJC51_RS10115	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EJC51_RS10120	COG1196	nuclear chromosome segregation
EJC51_RS10125	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EJC51_RS10135	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EJC51_RS10140	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EJC51_RS10145	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EJC51_RS10155	COG2255	four-way junction helicase activity
EJC51_RS10160	COG0632	four-way junction helicase activity
EJC51_RS10165	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EJC51_RS10170	COG0217	transcriptional regulatory protein
EJC51_RS10175	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EJC51_RS10180	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EJC51_RS10190	COG0438	transferase activity, transferring glycosyl groups
EJC51_RS10195	COG1560	Kdo2-lipid A biosynthetic process
EJC51_RS10200	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EJC51_RS10225	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EJC51_RS10240	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EJC51_RS10270	COG0395	ABC-type sugar transport system, permease component
EJC51_RS10275	COG1175	transmembrane transport
EJC51_RS10280	COG1653	transport
EJC51_RS10325	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EJC51_RS10385	COG1648	precorrin-2 dehydrogenase activity
EJC51_RS10385	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EJC51_RS10390	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EJC51_RS10405	COG1464	Belongs to the NlpA lipoprotein family
EJC51_RS10410	COG1464	Belongs to the NlpA lipoprotein family
EJC51_RS10415	COG2011	ABC-type metal ion transport system permease component
EJC51_RS10420	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EJC51_RS10425	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EJC51_RS10455	COG0204	Acyl-transferase
EJC51_RS10455	COG0318	PFAM AMP-dependent synthetase and ligase
EJC51_RS10460	COG0477	Major facilitator Superfamily
EJC51_RS10475	COG0165	Argininosuccinate lyase
EJC51_RS10495	COG2205	protein histidine kinase activity
EJC51_RS10500	COG0745	RESPONSE REGULATOR receiver
EJC51_RS10505	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EJC51_RS10505	COG1017	nitric oxide dioxygenase activity
EJC51_RS10530	COG1438	arginine binding
EJC51_RS10535	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EJC51_RS10540	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EJC51_RS10545	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EJC51_RS10550	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EJC51_RS10580	COG0456	acetyltransferase
EJC51_RS10590	COG0697	spore germination
EJC51_RS10600	COG1649	PFAM Uncharacterised BCR, COG1649
EJC51_RS10630	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EJC51_RS10630	COG0072	phenylalanine-tRNA ligase activity
EJC51_RS10635	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EJC51_RS10640	COG5002	protein histidine kinase activity
EJC51_RS10645	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EJC51_RS10650	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EJC51_RS10655	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EJC51_RS10660	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EJC51_RS10705	COG1012	belongs to the aldehyde dehydrogenase family
EJC51_RS10710	COG0174	glutamine synthetase
EJC51_RS10720	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EJC51_RS10740	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EJC51_RS10750	COG4176	ABC-type proline glycine betaine transport system permease component
EJC51_RS10755	COG0517	IMP dehydrogenase activity
EJC51_RS10755	COG4175	Glycine betaine
EJC51_RS10765	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EJC51_RS10800	COG2124	cytochrome p450
EJC51_RS10860	COG0805	protein transport
EJC51_RS10865	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EJC51_RS10895	COG0545	Peptidyl-prolyl cis-trans isomerase
EJC51_RS10900	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
EJC51_RS10910	COG1609	Transcriptional regulator
EJC51_RS10915	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
EJC51_RS10920	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
EJC51_RS10935	COG4122	O-methyltransferase activity
EJC51_RS10940	COG1222	aaa ATPase
EJC51_RS10960	COG1994	Peptidase M50
EJC51_RS10960	COG0517	IMP dehydrogenase activity
EJC51_RS10970	COG2197	response regulator
EJC51_RS10975	COG4166	transmembrane transport
EJC51_RS10980	COG0747	negative chemotaxis
EJC51_RS10985	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EJC51_RS10990	COG1410	methionine synthase
EJC51_RS10990	COG0646	methionine synthase
EJC51_RS10995	COG1414	Transcriptional regulator
EJC51_RS11000	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EJC51_RS11005	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EJC51_RS11010	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EJC51_RS11020	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EJC51_RS11030	COG1129	ABC transporter
EJC51_RS11040	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EJC51_RS11045	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
EJC51_RS11055	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EJC51_RS11065	COG3845	ABC transporter
EJC51_RS11070	COG4603	Belongs to the binding-protein-dependent transport system permease family
EJC51_RS11075	COG1079	Belongs to the binding-protein-dependent transport system permease family
EJC51_RS11085	COG0402	S-adenosylhomocysteine deaminase activity
EJC51_RS11090	COG2186	Transcriptional regulator
EJC51_RS11105	COG1404	Belongs to the peptidase S8 family
EJC51_RS11105	COG4935	Belongs to the peptidase S8 family
EJC51_RS11115	COG0215	cysteine-tRNA ligase activity
EJC51_RS11130	COG0588	phosphoglycerate mutase activity
EJC51_RS11135	COG0598	Magnesium transport protein CorA
EJC51_RS11145	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EJC51_RS11150	COG0667	Aldo Keto reductase
EJC51_RS11180	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EJC51_RS11195	COG0308	aminopeptidase N
EJC51_RS11200	COG3012	SEC-C Motif Domain Protein
EJC51_RS11205	COG2186	Transcriptional regulator
EJC51_RS11210	COG3265	gluconokinase activity
EJC51_RS11250	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EJC51_RS11260	COG2149	membrane
EJC51_RS11300	COG0318	PFAM AMP-dependent synthetase and ligase
EJC51_RS11310	COG3876	Protein conserved in bacteria
EJC51_RS11345	COG0789	Transcriptional regulator
EJC51_RS11365	COG1960	acyl-CoA dehydrogenase activity
EJC51_RS11375	COG0640	Transcriptional regulator
EJC51_RS11380	COG0697	spore germination
EJC51_RS11415	COG2851	Citrate transporter
EJC51_RS11420	COG0243	molybdopterin cofactor binding
EJC51_RS11425	COG1309	transcriptional regulator
EJC51_RS11435	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
EJC51_RS11440	COG2188	Transcriptional regulator
EJC51_RS11475	COG1595	DNA-templated transcription, initiation
EJC51_RS11485	COG0457	Tetratricopeptide repeat
EJC51_RS11500	COG2755	lipolytic protein G-D-S-L family
EJC51_RS11530	COG1649	PFAM Uncharacterised BCR, COG1649
EJC51_RS11530	COG0726	polysaccharide deacetylase
EJC51_RS11555	COG1725	Transcriptional regulator
EJC51_RS11580	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EJC51_RS11580	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EJC51_RS11605	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EJC51_RS11610	COG0587	DNA-directed DNA polymerase activity
EJC51_RS11625	COG0330	HflC and HflK could
EJC51_RS11645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EJC51_RS11685	COG1799	cell septum assembly
EJC51_RS11690	COG1960	acyl-CoA dehydrogenase activity
EJC51_RS11695	COG0477	Major facilitator Superfamily
EJC51_RS11705	COG0671	phosphoesterase, PA-phosphatase related
EJC51_RS11760	COG1652	LysM domain
EJC51_RS11775	COG1160	GTP binding
EJC51_RS11785	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EJC51_RS11825	COG0494	nUDIX hydrolase
EJC51_RS11850	COG1187	pseudouridine synthase activity
EJC51_RS11855	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EJC51_RS11860	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EJC51_RS11875	COG0686	Belongs to the AlaDH PNT family
EJC51_RS11885	COG0494	nUDIX hydrolase
EJC51_RS11890	COG0504	CTP synthase activity
EJC51_RS11895	COG3387	PFAM Glycoside hydrolase 15-related
EJC51_RS11910	COG0438	transferase activity, transferring glycosyl groups
EJC51_RS11915	COG0497	DNA recombination
EJC51_RS11920	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EJC51_RS11940	COG1120	ATPase activity
EJC51_RS11945	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EJC51_RS11950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EJC51_RS11955	COG0647	UMP catabolic process
EJC51_RS11995	COG2094	Belongs to the DNA glycosylase MPG family
EJC51_RS12005	COG1881	PFAM PEBP family protein
EJC51_RS12025	COG1119	ATPase activity
EJC51_RS12045	COG2197	response regulator
EJC51_RS12055	COG4221	oxidoreductase activity
EJC51_RS12070	COG0842	Transport permease protein
EJC51_RS12070	COG1716	ATPase activity
EJC51_RS12070	COG1131	(ABC) transporter
EJC51_RS12085	COG3830	Belongs to the UPF0237 family
EJC51_RS12085	COG0560	Phosphoserine phosphatase
EJC51_RS12110	COG2186	Transcriptional regulator
EJC51_RS12120	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EJC51_RS12125	COG1028	Short-chain dehydrogenase reductase Sdr
EJC51_RS12140	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EJC51_RS12160	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EJC51_RS12165	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EJC51_RS12180	COG1404	Belongs to the peptidase S8 family
EJC51_RS12190	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EJC51_RS12200	COG1063	alcohol dehydrogenase
EJC51_RS12230	COG0300	oxidoreductase activity
EJC51_RS12250	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EJC51_RS12265	COG3387	PFAM Glycoside hydrolase 15-related
EJC51_RS12305	COG1024	Enoyl-CoA hydratase
EJC51_RS12315	COG0488	(ABC) transporter
EJC51_RS12340	COG0235	Class ii aldolase
EJC51_RS12360	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
EJC51_RS12365	COG1492	cobalamin metabolic process
EJC51_RS12385	COG1797	cobyrinic acid a,c-diamide synthase activity
EJC51_RS12440	COG1126	abc transporter atp-binding protein
EJC51_RS12445	COG0765	amino acid transport
EJC51_RS12455	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EJC51_RS12460	COG2318	DinB family
EJC51_RS12465	COG0456	acetyltransferase
EJC51_RS12470	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EJC51_RS12475	COG1917	Cupin 2, conserved barrel domain protein
EJC51_RS12480	COG5285	phytanoyl-CoA dioxygenase
EJC51_RS12485	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EJC51_RS12515	COG1414	Transcriptional regulator
EJC51_RS12530	COG2252	PERMEase
EJC51_RS12535	COG1595	DNA-templated transcription, initiation
EJC51_RS12560	COG4677	pectinesterase activity
EJC51_RS12565	COG4677	pectinesterase activity
EJC51_RS12570	COG3866	Pectate lyase
EJC51_RS12575	COG2755	lipolytic protein G-D-S-L family
EJC51_RS12600	COG0395	ABC-type sugar transport system, permease component
EJC51_RS12605	COG1175	transmembrane transport
EJC51_RS12620	COG1802	Transcriptional regulator
EJC51_RS12640	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EJC51_RS12645	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EJC51_RS12650	COG1349	DNA-binding transcription factor activity
EJC51_RS12665	COG0395	ABC-type sugar transport system, permease component
EJC51_RS12670	COG1063	alcohol dehydrogenase
EJC51_RS12685	COG0583	DNA-binding transcription factor activity
EJC51_RS12700	COG1802	Transcriptional regulator
EJC51_RS12745	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EJC51_RS12755	COG1595	DNA-templated transcription, initiation
EJC51_RS12770	COG2171	N-acyltransferase activity
EJC51_RS12785	COG3226	Transcriptional regulator
EJC51_RS12790	COG2076	Multidrug Resistance protein
EJC51_RS12800	COG2151	metal-sulfur cluster biosynthetic enzyme
EJC51_RS12805	COG0822	iron-sulfur transferase activity
EJC51_RS12810	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EJC51_RS12815	COG0396	ATPase activity
EJC51_RS12825	COG0719	Fe-S assembly protein
EJC51_RS12840	COG2746	aminoglycoside 3-N-acetyltransferase activity
EJC51_RS12845	COG1131	(ABC) transporter
EJC51_RS12875	COG0109	protoheme IX farnesyltransferase activity
EJC51_RS12890	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EJC51_RS12905	COG0363	glucosamine-6-phosphate deaminase activity
EJC51_RS12915	COG0166	Belongs to the GPI family
EJC51_RS12930	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EJC51_RS12935	COG0149	triose-phosphate isomerase activity
EJC51_RS12940	COG0126	phosphoglycerate kinase activity
EJC51_RS12945	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EJC51_RS12955	COG1481	regulation of sporulation
EJC51_RS12960	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EJC51_RS12965	COG1660	Displays ATPase and GTPase activities
EJC51_RS12970	COG0322	excinuclease ABC activity
EJC51_RS12990	COG1609	Transcriptional regulator
EJC51_RS13000	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EJC51_RS13010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EJC51_RS13015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EJC51_RS13020	COG0765	amino acid transport
EJC51_RS13030	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EJC51_RS13035	COG1619	proteins homologs of microcin C7 resistance protein MccF
EJC51_RS13040	COG0477	Major facilitator Superfamily
EJC51_RS13045	COG0387	Pfam Sodium calcium exchanger
EJC51_RS13070	COG0556	nucleotide-excision repair
EJC51_RS13080	COG0584	glycerophosphoryl diester phosphodiesterase
EJC51_RS13085	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EJC51_RS13090	COG1063	alcohol dehydrogenase
EJC51_RS13100	COG2313	pseudouridylate synthase activity
EJC51_RS13110	COG2226	methyltransferase
EJC51_RS13115	COG0598	Magnesium transport protein CorA
EJC51_RS13140	COG2910	NAD(P)H-binding
EJC51_RS13160	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EJC51_RS13165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EJC51_RS13170	COG0574	Belongs to the PEP-utilizing enzyme family
EJC51_RS13170	COG3848	Pyruvate phosphate dikinase
EJC51_RS13205	COG1132	(ABC) transporter
EJC51_RS13220	COG0402	S-adenosylhomocysteine deaminase activity
EJC51_RS13240	COG1136	(ABC) transporter
EJC51_RS13265	COG0515	serine threonine protein kinase
EJC51_RS13265	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EJC51_RS13270	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EJC51_RS13310	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EJC51_RS13350	COG0210	DNA helicase
EJC51_RS13385	COG1953	Uracil, thiamine, allantoin
EJC51_RS13390	COG1802	Transcriptional regulator
EJC51_RS13410	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EJC51_RS13430	COG0237	dephospho-CoA kinase activity
EJC51_RS13440	COG0539	negative regulation of cytoplasmic translation
EJC51_RS13445	COG2226	methyltransferase
EJC51_RS13455	COG1643	Atp-dependent helicase
EJC51_RS13495	COG2050	protein possibly involved in aromatic compounds catabolism
EJC51_RS13560	COG0737	Belongs to the 5'-nucleotidase family
EJC51_RS13580	COG0745	RESPONSE REGULATOR receiver
EJC51_RS13585	COG1605	Chorismate mutase
EJC51_RS13585	COG0287	Prephenate dehydrogenase
EJC51_RS13605	COG0477	Major facilitator Superfamily
EJC51_RS13610	COG1846	Transcriptional regulator
EJC51_RS13615	COG1028	Short-chain dehydrogenase reductase Sdr
EJC51_RS13625	COG1024	Enoyl-CoA hydratase
EJC51_RS13645	COG0183	Belongs to the thiolase family
EJC51_RS13650	COG1309	transcriptional regulator
EJC51_RS13660	COG1960	acyl-CoA dehydrogenase activity
EJC51_RS13665	COG1960	acyl-CoA dehydrogenase activity
EJC51_RS13670	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EJC51_RS13680	COG0667	Aldo Keto reductase
EJC51_RS13685	COG2304	oxidoreductase activity
EJC51_RS13710	COG1215	transferase activity, transferring glycosyl groups
EJC51_RS13715	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EJC51_RS13730	COG0070	glutamate synthase
EJC51_RS13730	COG0069	glutamate synthase activity
EJC51_RS13730	COG0067	glutamate synthase
EJC51_RS13740	COG1397	ADP-ribosylglycohydrolase
EJC51_RS13765	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EJC51_RS13770	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EJC51_RS13780	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EJC51_RS13790	COG0159	tryptophan synthase activity
EJC51_RS13795	COG0133	tryptophan synthase activity
EJC51_RS13805	COG0134	indole-3-glycerol-phosphate synthase activity
EJC51_RS13825	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EJC51_RS13830	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EJC51_RS13850	COG0107	imidazoleglycerol-phosphate synthase activity
EJC51_RS13855	COG0251	oxidation-reduction process
EJC51_RS13860	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EJC51_RS13865	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EJC51_RS13870	COG0131	Imidazoleglycerol-phosphate dehydratase
EJC51_RS13875	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EJC51_RS13880	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EJC51_RS13900	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EJC51_RS13920	COG1432	Conserved Protein
EJC51_RS13925	COG0587	DNA-directed DNA polymerase activity
EJC51_RS13985	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EJC51_RS14000	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EJC51_RS14005	COG3599	regulation of cell shape
EJC51_RS14015	COG1799	cell septum assembly
EJC51_RS14025	COG1496	oxidoreductase activity
EJC51_RS14030	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EJC51_RS14035	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EJC51_RS14040	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EJC51_RS14050	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EJC51_RS14055	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EJC51_RS14065	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EJC51_RS14070	COG0768	penicillin binding
EJC51_RS14080	COG0275	rRNA processing
EJC51_RS14090	COG0714	Associated with various cellular activities
EJC51_RS14110	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EJC51_RS14120	COG1126	abc transporter atp-binding protein
EJC51_RS14130	COG1309	transcriptional regulator
EJC51_RS14140	COG1233	COG1233 Phytoene dehydrogenase and related
EJC51_RS14155	COG0352	thiamine-phosphate diphosphorylase activity
EJC51_RS14175	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EJC51_RS14175	COG2022	thiamine diphosphate biosynthetic process
EJC51_RS14185	COG2022	thiamine diphosphate biosynthetic process
EJC51_RS14190	COG2815	serine threonine protein kinase
EJC51_RS14190	COG0515	serine threonine protein kinase
EJC51_RS14195	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EJC51_RS14205	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EJC51_RS14210	COG2193	ferroxidase activity
EJC51_RS14215	COG0243	molybdopterin cofactor binding
EJC51_RS14220	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
EJC51_RS14235	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EJC51_RS14240	COG0205	6-phosphofructokinase activity
EJC51_RS14245	COG2197	response regulator
EJC51_RS14250	COG4585	Histidine kinase
EJC51_RS14275	COG1940	carbohydrate kinase activity
EJC51_RS14285	COG0003	Pfam Anion-transporting ATPase
EJC51_RS14320	COG0534	Mate efflux family protein
EJC51_RS14365	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EJC51_RS14365	COG0515	serine threonine protein kinase
EJC51_RS14370	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EJC51_RS14375	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EJC51_RS14380	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EJC51_RS14385	COG0723	plastoquinol--plastocyanin reductase activity
EJC51_RS14390	COG2010	Cytochrome c
EJC51_RS14395	COG1845	cytochrome c oxidase, subunit III
EJC51_RS14405	COG1376	ErfK ybiS ycfS ynhG family protein
EJC51_RS14415	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EJC51_RS14420	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EJC51_RS14430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EJC51_RS14450	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EJC51_RS14455	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EJC51_RS14455	COG0515	serine threonine protein kinase
EJC51_RS14460	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EJC51_RS14465	COG2197	response regulator
EJC51_RS14470	COG4585	Histidine kinase
EJC51_RS14490	COG2226	methyltransferase
EJC51_RS14495	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EJC51_RS14515	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EJC51_RS14520	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EJC51_RS14520	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EJC51_RS14535	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
EJC51_RS14555	COG0438	transferase activity, transferring glycosyl groups
EJC51_RS14565	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EJC51_RS14570	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EJC51_RS14575	COG0508	dehydrogenase complex catalyzes the overall conversion of
EJC51_RS14590	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
EJC51_RS14635	COG1090	epimerase
EJC51_RS14650	COG0321	lipoyl(octanoyl) transferase activity
EJC51_RS14655	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EJC51_RS14675	COG0174	glutamine synthetase
EJC51_RS14690	COG0501	Belongs to the peptidase M48B family
EJC51_RS14760	COG0745	RESPONSE REGULATOR receiver
EJC51_RS14770	COG4585	Histidine kinase
EJC51_RS14775	COG2197	response regulator
EJC51_RS14810	COG1309	transcriptional regulator
EJC51_RS14840	COG0366	Alpha amylase catalytic
EJC51_RS14845	COG3833	ABC-type maltose transport systems, permease component
EJC51_RS14850	COG1175	transmembrane transport
EJC51_RS14860	COG1609	Transcriptional regulator
EJC51_RS14870	COG0583	DNA-binding transcription factor activity
EJC51_RS14875	COG0697	spore germination
EJC51_RS14880	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EJC51_RS14895	COG3511	phospholipase C
EJC51_RS14910	COG0174	glutamine synthetase
EJC51_RS14935	COG2814	Major facilitator Superfamily
EJC51_RS14950	COG0477	Major facilitator Superfamily
EJC51_RS14955	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EJC51_RS14975	COG1994	Peptidase M50
EJC51_RS15020	COG2822	iron ion transport
EJC51_RS15025	COG2837	iron assimilation
EJC51_RS15030	COG0672	)-iron permease
EJC51_RS15055	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EJC51_RS15060	COG2814	Major facilitator Superfamily
EJC51_RS15070	COG3540	Alkaline phosphatase
EJC51_RS15085	COG1136	(ABC) transporter
EJC51_RS15095	COG2259	Doxx family
EJC51_RS15125	COG3629	intracellular signal transduction
EJC51_RS15125	COG3903	Transcriptional regulator
EJC51_RS15130	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EJC51_RS15140	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EJC51_RS15145	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EJC51_RS15160	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EJC51_RS15185	COG1012	belongs to the aldehyde dehydrogenase family
EJC51_RS15190	COG0477	Major facilitator Superfamily
EJC51_RS15220	COG3321	synthase
EJC51_RS15220	COG0604	alcohol dehydrogenase
EJC51_RS15295	COG3022	response to hydroperoxide
EJC51_RS15300	COG0800	Aldolase
EJC51_RS15315	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EJC51_RS15325	COG1028	Short-chain dehydrogenase reductase Sdr
EJC51_RS15335	COG2030	dehydratase
EJC51_RS15340	COG4585	Histidine kinase
EJC51_RS15345	COG2197	response regulator
EJC51_RS15355	COG1733	regulation of RNA biosynthetic process
EJC51_RS15375	COG0477	Major facilitator Superfamily
EJC51_RS15395	COG0860	N-Acetylmuramoyl-L-alanine amidase
EJC51_RS15405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EJC51_RS15430	COG0438	transferase activity, transferring glycosyl groups
EJC51_RS15435	COG1309	transcriptional regulator
EJC51_RS15470	COG1657	PFAM Prenyltransferase squalene oxidase
EJC51_RS15485	COG3845	ABC transporter
EJC51_RS15500	COG3619	membrane
EJC51_RS15525	COG0183	Belongs to the thiolase family
EJC51_RS15530	COG2124	cytochrome p450
EJC51_RS15535	COG2072	flavoprotein involved in K transport
EJC51_RS15545	COG2197	response regulator
EJC51_RS15560	COG4122	O-methyltransferase activity
EJC51_RS15610	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EJC51_RS15650	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EJC51_RS15655	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EJC51_RS15695	COG1358	cellular component organization or biogenesis
EJC51_RS15740	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
EJC51_RS15745	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EJC51_RS15760	COG0477	Major facilitator Superfamily
EJC51_RS15765	COG1309	transcriptional regulator
EJC51_RS15780	COG0667	Aldo Keto reductase
EJC51_RS15785	COG0789	Transcriptional regulator
EJC51_RS15815	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EJC51_RS15820	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EJC51_RS15825	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EJC51_RS15865	COG0583	DNA-binding transcription factor activity
EJC51_RS15875	COG1280	lysine exporter protein (LysE YggA)
EJC51_RS15900	COG1764	response to oxidative stress
EJC51_RS15905	COG2130	NADP-dependent
EJC51_RS15925	COG1172	Belongs to the binding-protein-dependent transport system permease family
EJC51_RS15930	COG1172	Belongs to the binding-protein-dependent transport system permease family
EJC51_RS15940	COG1879	ABC-type sugar transport system periplasmic component
EJC51_RS15945	COG1609	Transcriptional regulator
EJC51_RS15950	COG4948	Mandelate Racemase Muconate Lactonizing
EJC51_RS15965	COG4213	ABC transporter substrate-binding protein
EJC51_RS15975	COG4214	carbohydrate transport
EJC51_RS15985	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EJC51_RS16005	COG3485	protocatechuate 3,4-dioxygenase
EJC51_RS16055	COG3386	PFAM SMP-30 Gluconolaconase
EJC51_RS16060	COG1414	Transcriptional regulator
EJC51_RS16095	COG4981	capsule polysaccharide biosynthetic process
EJC51_RS16140	COG0318	PFAM AMP-dependent synthetase and ligase
EJC51_RS16145	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EJC51_RS16145	COG0825	malonyl-CoA metabolic process
EJC51_RS16170	COG1077	Cell shape determining protein MreB Mrl
EJC51_RS16185	COG2205	protein histidine kinase activity
EJC51_RS16190	COG0745	RESPONSE REGULATOR receiver
EJC51_RS16220	COG2205	protein histidine kinase activity
EJC51_RS16225	COG0745	RESPONSE REGULATOR receiver
EJC51_RS16250	COG1070	Carbohydrate kinase
EJC51_RS16265	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EJC51_RS16270	COG0358	DNA primase activity
EJC51_RS16280	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EJC51_RS16290	COG2949	membrane
EJC51_RS16310	COG0243	molybdopterin cofactor binding
EJC51_RS16340	COG0477	Major facilitator Superfamily
EJC51_RS16365	COG3896	Chloramphenicol phosphotransferase-like protein
EJC51_RS16380	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EJC51_RS16385	COG2146	nitrite reductase [NAD(P)H] activity
EJC51_RS16385	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EJC51_RS16395	COG1309	transcriptional regulator
EJC51_RS16400	COG1028	Short-chain dehydrogenase reductase Sdr
EJC51_RS16430	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EJC51_RS16430	COG0574	Belongs to the PEP-utilizing enzyme family
EJC51_RS16435	COG1940	carbohydrate kinase activity
EJC51_RS16435	COG1846	Transcriptional regulator
EJC51_RS16440	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
EJC51_RS16475	COG0477	Major facilitator Superfamily
EJC51_RS16490	COG0667	Aldo Keto reductase
EJC51_RS16500	COG0423	glycine-tRNA ligase activity
EJC51_RS16510	COG1121	(ABC) transporter
EJC51_RS16515	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EJC51_RS16535	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EJC51_RS16540	COG1381	Involved in DNA repair and RecF pathway recombination
EJC51_RS16595	COG2197	response regulator
EJC51_RS16600	COG4585	Histidine kinase
EJC51_RS16605	COG2409	Drug exporters of the RND superfamily
EJC51_RS16615	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EJC51_RS16635	COG2723	6-phospho-beta-galactosidase activity
EJC51_RS16655	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EJC51_RS16705	COG3903	Transcriptional regulator
EJC51_RS16705	COG3629	intracellular signal transduction
EJC51_RS16740	COG2315	Protein conserved in bacteria
EJC51_RS16750	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EJC51_RS16770	COG4948	Mandelate Racemase Muconate Lactonizing
EJC51_RS16775	COG1414	Transcriptional regulator
EJC51_RS16785	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EJC51_RS16790	COG1234	tRNA 3'-trailer cleavage
EJC51_RS16795	COG0537	adenosine 5'-monophosphoramidase activity
EJC51_RS16800	COG0793	Belongs to the peptidase S41A family
EJC51_RS16800	COG4946	Tricorn protease homolog
EJC51_RS16825	COG0484	heat shock protein binding
EJC51_RS16830	COG1420	regulation of RNA biosynthetic process
EJC51_RS16855	COG2837	iron assimilation
EJC51_RS16895	COG0481	GTPase activity
EJC51_RS16900	COG0268	Binds directly to 16S ribosomal RNA
EJC51_RS16925	COG2333	competence protein COMEC
EJC51_RS16925	COG0658	competence protein
EJC51_RS16930	COG1555	photosystem II stabilization
EJC51_RS16930	COG1596	polysaccharide export
EJC51_RS16935	COG1307	EDD domain protein, DegV family
EJC51_RS16945	COG0495	leucyl-tRNA aminoacylation
EJC51_RS16980	COG0477	Major facilitator Superfamily
EJC51_RS16995	COG0588	phosphoglycerate mutase activity
EJC51_RS17000	COG0799	negative regulation of ribosome biogenesis
EJC51_RS17010	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EJC51_RS17015	COG0501	Belongs to the peptidase M48B family
EJC51_RS17030	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EJC51_RS17040	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EJC51_RS17055	COG1215	transferase activity, transferring glycosyl groups
EJC51_RS17075	COG3540	Alkaline phosphatase
EJC51_RS17095	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EJC51_RS17100	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EJC51_RS17105	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EJC51_RS17135	COG1530	ribonuclease E activity
EJC51_RS17190	COG0772	Belongs to the SEDS family
EJC51_RS17210	COG1077	Cell shape determining protein MreB Mrl
EJC51_RS17215	COG0105	UTP biosynthetic process
EJC51_RS17225	COG0285	dihydrofolate synthase activity
EJC51_RS17230	COG0525	valine-tRNA ligase activity
EJC51_RS17240	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EJC51_RS17245	COG0740	serine-type endopeptidase activity
EJC51_RS17250	COG0740	serine-type endopeptidase activity
EJC51_RS17255	COG0544	peptidyl-prolyl cis-trans isomerase activity
EJC51_RS17290	COG3594	Acyltransferase
EJC51_RS17305	COG0577	efflux transmembrane transporter activity
EJC51_RS17305	COG1136	(ABC) transporter
EJC51_RS17315	COG4552	Acetyltransferase involved in intracellular survival and related
EJC51_RS17325	COG0698	ribose 5-phosphate isomerase
EJC51_RS17330	COG1113	amino acid transport
EJC51_RS17335	COG0515	serine threonine protein kinase
EJC51_RS17355	COG1940	carbohydrate kinase activity
EJC51_RS17365	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EJC51_RS17370	COG1116	anion transmembrane transporter activity
EJC51_RS17375	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EJC51_RS17385	COG1113	amino acid transport
EJC51_RS17390	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EJC51_RS17400	COG0588	phosphoglycerate mutase activity
EJC51_RS17410	COG1349	DNA-binding transcription factor activity
EJC51_RS17420	COG1070	Carbohydrate kinase
EJC51_RS17430	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EJC51_RS17535	COG0697	spore germination
EJC51_RS17540	COG0697	spore germination
EJC51_RS17545	COG1846	Transcriptional regulator
EJC51_RS17550	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EJC51_RS17580	COG1136	(ABC) transporter
EJC51_RS17595	COG0668	transmembrane transport
EJC51_RS17615	COG1653	transport
EJC51_RS17620	COG1175	transmembrane transport
EJC51_RS17625	COG0395	ABC-type sugar transport system, permease component
EJC51_RS17630	COG1486	melibiose metabolic process
EJC51_RS17645	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EJC51_RS17675	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EJC51_RS17695	COG0577	efflux transmembrane transporter activity
EJC51_RS17695	COG1136	(ABC) transporter
EJC51_RS17725	COG0629	single-stranded DNA binding
EJC51_RS17765	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EJC51_RS17775	COG1051	belongs to the nudix hydrolase family
EJC51_RS17790	COG2813	Specifically methylates the guanine in position
EJC51_RS17800	COG0181	hydroxymethylbilane synthase activity
EJC51_RS17815	COG0494	nUDIX hydrolase
EJC51_RS17845	COG0438	transferase activity, transferring glycosyl groups
EJC51_RS17885	COG1720	tRNA m6t6A37 methyltransferase activity
EJC51_RS17915	COG2771	luxR family
EJC51_RS17950	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EJC51_RS17980	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EJC51_RS18040	COG1132	(ABC) transporter
EJC51_RS18090	COG0154	amidase activity
EJC51_RS18230	COG0151	Belongs to the GarS family
EJC51_RS18310	COG0791	NLP P60 protein
EJC51_RS18310	COG3883	PFAM NLP P60 protein
EJC51_RS18415	COG0714	Associated with various cellular activities
EJC51_RS18540	COG0519	Catalyzes the synthesis of GMP from XMP
EJC51_RS18555	COG1104	cysteine desulfurase activity
EJC51_RS18560	COG1061	Type III restriction enzyme res subunit
EJC51_RS18615	COG0017	Asparaginyl-tRNA synthetase
EJC51_RS18655	COG2304	oxidoreductase activity
EJC51_RS18720	COG0438	transferase activity, transferring glycosyl groups
EJC51_RS18745	COG0492	ferredoxin-NADP+ reductase activity
EJC51_RS18820	COG3962	Belongs to the TPP enzyme family
EJC51_RS18825	COG3718	enzyme involved in inositol metabolism
EJC51_RS18835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EJC51_RS18860	COG1063	alcohol dehydrogenase
EJC51_RS18865	COG0475	glutathione-regulated potassium exporter activity
EJC51_RS18865	COG0569	domain protein
EJC51_RS18885	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EJC51_RS18910	COG1396	sequence-specific DNA binding
EJC51_RS18925	COG1129	ABC transporter
EJC51_RS18930	COG1879	ABC-type sugar transport system periplasmic component
EJC51_RS18935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EJC51_RS18940	COG1869	D-ribose catabolic process
EJC51_RS18965	COG0673	inositol 2-dehydrogenase activity
EJC51_RS18970	COG1609	Transcriptional regulator
EJC51_RS18995	COG0456	acetyltransferase
EJC51_RS18995	COG1846	Transcriptional regulator
EJC51_RS19025	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EJC51_RS19045	COG1472	Belongs to the glycosyl hydrolase 3 family
EJC51_RS19085	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EJC51_RS19090	COG2356	endonuclease I
EJC51_RS19095	COG0028	Belongs to the TPP enzyme family
EJC51_RS19105	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EJC51_RS19125	COG1946	Acyl-CoA thioesterase
EJC51_RS19135	COG1309	transcriptional regulator
EJC51_RS19140	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EJC51_RS19155	COG1960	acyl-CoA dehydrogenase activity
EJC51_RS19165	COG3209	COG3209 Rhs family protein
EJC51_RS19205	COG3486	L-lysine 6-monooxygenase (NADPH) activity
EJC51_RS19240	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EJC51_RS19250	COG0589	response to stress
EJC51_RS19260	COG4977	sequence-specific DNA binding
EJC51_RS19265	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EJC51_RS19295	COG0395	ABC-type sugar transport system, permease component
EJC51_RS19305	COG3979	chitinase
EJC51_RS19315	COG0745	RESPONSE REGULATOR receiver
EJC51_RS19340	COG0406	alpha-ribazole phosphatase activity
EJC51_RS19390	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EJC51_RS19425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EJC51_RS19430	COG0765	amino acid transport
EJC51_RS19435	COG0765	amino acid transport
EJC51_RS19440	COG1126	abc transporter atp-binding protein
EJC51_RS19455	COG0318	PFAM AMP-dependent synthetase and ligase
EJC51_RS19465	COG3397	chitin binding
EJC51_RS19550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EJC51_RS19555	COG2188	Transcriptional regulator
EJC51_RS19570	COG0673	inositol 2-dehydrogenase activity
EJC51_RS19575	COG4702	Belongs to the UPF0303 family
EJC51_RS19585	COG0706	membrane insertase activity
EJC51_RS19605	COG3764	Sortase (surface protein transpeptidase)
EJC51_RS19740	COG2733	membrane
EJC51_RS19755	COG4555	ABC transporter
EJC51_RS19770	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EJC51_RS19805	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EJC51_RS19815	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EJC51_RS19820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EJC51_RS19825	COG1263	PTS System
EJC51_RS19830	COG1263	PTS System
EJC51_RS19835	COG1234	tRNA 3'-trailer cleavage
EJC51_RS19870	COG1113	amino acid transport
EJC51_RS19885	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EJC51_RS19895	COG1335	isochorismatase
EJC51_RS19930	COG0277	FAD linked oxidase domain protein
EJC51_RS19960	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EJC51_RS19970	COG1174	glycine betaine transport
EJC51_RS19980	COG1174	glycine betaine transport
EJC51_RS20015	COG3654	unkown
EJC51_RS20060	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EJC51_RS20065	COG0395	ABC-type sugar transport system, permease component
EJC51_RS20070	COG1175	transmembrane transport
EJC51_RS20090	COG1678	Uncharacterized ACR, COG1678
EJC51_RS20095	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EJC51_RS20100	COG0776	regulation of translation
EJC51_RS20110	COG3973	AAA domain
EJC51_RS20140	COG2223	nitrite transmembrane transporter activity
EJC51_RS20220	COG3655	Transcriptional regulator
EJC51_RS20260	COG0583	DNA-binding transcription factor activity
EJC51_RS20270	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EJC51_RS20270	COG2124	cytochrome p450
EJC51_RS20280	COG4209	transmembrane transport
EJC51_RS20285	COG0395	ABC-type sugar transport system, permease component
EJC51_RS20290	COG1501	Belongs to the glycosyl hydrolase 31 family
EJC51_RS20300	COG1472	Belongs to the glycosyl hydrolase 3 family
EJC51_RS20305	COG2027	D-alanyl-D-alanine carboxypeptidase
EJC51_RS20325	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EJC51_RS20330	COG0793	Belongs to the peptidase S41A family
EJC51_RS20340	COG2884	Cell division ATP-binding protein ftsE
EJC51_RS20355	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EJC51_RS20360	COG0515	serine threonine protein kinase
EJC51_RS20365	COG0515	serine threonine protein kinase
EJC51_RS20375	COG1653	transport
EJC51_RS20380	COG1175	transmembrane transport
EJC51_RS20385	COG0395	ABC-type sugar transport system, permease component
EJC51_RS20390	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EJC51_RS20390	COG0463	Glycosyl transferase, family 2
EJC51_RS20395	COG1764	response to oxidative stress
EJC51_RS20400	COG1846	Transcriptional regulator
EJC51_RS20430	COG1134	teichoic acid transport
EJC51_RS20465	COG0653	protein targeting
EJC51_RS20475	COG3214	Protein conserved in bacteria
EJC51_RS20480	COG2197	response regulator
EJC51_RS20485	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EJC51_RS20495	COG0823	Involved in the tonB-independent uptake of proteins
EJC51_RS20500	COG5002	protein histidine kinase activity
EJC51_RS20505	COG0745	RESPONSE REGULATOR receiver
EJC51_RS20595	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EJC51_RS20615	COG0714	Associated with various cellular activities
EJC51_RS20660	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EJC51_RS20665	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EJC51_RS20665	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EJC51_RS20665	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EJC51_RS20670	COG0681	Belongs to the peptidase S26 family
EJC51_RS20680	COG1482	cell wall glycoprotein biosynthetic process
EJC51_RS20690	COG2835	tetraacyldisaccharide 4'-kinase activity
EJC51_RS20730	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EJC51_RS20735	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
EJC51_RS20735	COG0778	Nitroreductase
EJC51_RS20760	COG1316	TRANSCRIPTIONal
EJC51_RS20765	COG1316	TRANSCRIPTIONal
EJC51_RS20770	COG1316	TRANSCRIPTIONal
EJC51_RS20775	COG1316	TRANSCRIPTIONal
EJC51_RS20785	COG1316	TRANSCRIPTIONal
EJC51_RS20800	COG1316	TRANSCRIPTIONal
EJC51_RS20815	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EJC51_RS20840	COG0789	Transcriptional regulator
EJC51_RS20845	COG1902	pentaerythritol trinitrate reductase activity
EJC51_RS20855	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EJC51_RS20870	COG2205	protein histidine kinase activity
EJC51_RS20875	COG0745	RESPONSE REGULATOR receiver
EJC51_RS20880	COG3104	oligopeptide transport
EJC51_RS20905	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EJC51_RS20920	COG1366	Belongs to the anti-sigma-factor antagonist family
EJC51_RS20925	COG1191	sigma factor activity
EJC51_RS20930	COG1228	amidohydrolase
EJC51_RS20940	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EJC51_RS20945	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EJC51_RS20995	COG1174	glycine betaine transport
EJC51_RS21000	COG1174	glycine betaine transport
EJC51_RS21010	COG0288	reversible hydration of carbon dioxide
EJC51_RS21020	COG1028	Short-chain dehydrogenase reductase Sdr
EJC51_RS21035	COG2755	lipolytic protein G-D-S-L family
EJC51_RS21040	COG0183	Belongs to the thiolase family
EJC51_RS21085	COG1136	(ABC) transporter
EJC51_RS21090	COG0577	efflux transmembrane transporter activity
EJC51_RS21095	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EJC51_RS21100	COG1252	NADH dehydrogenase
EJC51_RS21120	COG0148	phosphopyruvate hydratase activity
EJC51_RS21140	COG2124	cytochrome p450
EJC51_RS21220	COG0577	efflux transmembrane transporter activity
EJC51_RS21225	COG1136	(ABC) transporter
EJC51_RS21230	COG0477	Major facilitator Superfamily
EJC51_RS21245	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EJC51_RS21280	COG4585	Histidine kinase
EJC51_RS21295	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EJC51_RS21300	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EJC51_RS21305	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EJC51_RS21310	COG0193	aminoacyl-tRNA hydrolase activity
EJC51_RS21325	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EJC51_RS21335	COG1309	transcriptional regulator
EJC51_RS21350	COG4106	trans-aconitate 2-methyltransferase activity
EJC51_RS21360	COG2197	response regulator
EJC51_RS21390	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EJC51_RS21430	COG0488	(ABC) transporter
EJC51_RS21450	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EJC51_RS21460	COG3584	3D domain protein
EJC51_RS21460	COG3583	domain protein
EJC51_RS21465	COG0084	hydrolase, TatD family'
EJC51_RS21500	COG0310	cobalt ion transport
EJC51_RS21510	COG1122	ATPase activity
EJC51_RS21515	COG1846	Transcriptional regulator
EJC51_RS21520	COG1764	response to oxidative stress
EJC51_RS21525	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EJC51_RS21545	COG0442	prolyl-tRNA aminoacylation
EJC51_RS21555	COG2409	Drug exporters of the RND superfamily
EJC51_RS21565	COG0793	Belongs to the peptidase S41A family
EJC51_RS21565	COG4946	Tricorn protease homolog
EJC51_RS21570	COG1028	Short-chain dehydrogenase reductase Sdr
EJC51_RS21575	COG2267	carboxylic ester hydrolase activity
EJC51_RS21580	COG2072	flavoprotein involved in K transport
EJC51_RS21585	COG0789	Transcriptional regulator
EJC51_RS21590	COG0708	Exodeoxyribonuclease III
EJC51_RS21600	COG2197	response regulator
EJC51_RS21610	COG1136	(ABC) transporter
EJC51_RS21630	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EJC51_RS21635	COG0521	Mo-molybdopterin cofactor biosynthetic process
EJC51_RS21635	COG0315	cyclic pyranopterin monophosphate synthase activity
EJC51_RS21640	COG0315	cyclic pyranopterin monophosphate synthase activity
EJC51_RS21650	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EJC51_RS21655	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EJC51_RS21685	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EJC51_RS21695	COG1970	mechanosensitive ion channel activity
EJC51_RS21705	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EJC51_RS21720	COG3191	aminopeptidase activity
EJC51_RS21725	COG1376	ErfK ybiS ycfS ynhG family protein
EJC51_RS21750	COG1349	DNA-binding transcription factor activity
EJC51_RS21755	COG0477	Major facilitator Superfamily
EJC51_RS21775	COG3384	dioxygenase
EJC51_RS21780	COG1846	Transcriptional regulator
EJC51_RS21800	COG1414	Transcriptional regulator
EJC51_RS21870	COG3629	intracellular signal transduction
EJC51_RS21870	COG3903	Transcriptional regulator
EJC51_RS21890	COG0386	Belongs to the glutathione peroxidase family
EJC51_RS21905	COG1686	Belongs to the peptidase S11 family
EJC51_RS21990	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
EJC51_RS22045	COG2409	Drug exporters of the RND superfamily
EJC51_RS22055	COG1028	Short-chain dehydrogenase reductase Sdr
EJC51_RS22060	COG0667	Aldo Keto reductase
EJC51_RS22065	COG2814	Major facilitator Superfamily
EJC51_RS22070	COG2124	cytochrome p450
EJC51_RS22095	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EJC51_RS22110	COG0702	epimerase
EJC51_RS22125	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
EJC51_RS22150	COG3903	Transcriptional regulator
EJC51_RS22150	COG3629	intracellular signal transduction
EJC51_RS22175	COG1024	Enoyl-CoA hydratase
EJC51_RS22180	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EJC51_RS22180	COG0515	serine threonine protein kinase
EJC51_RS22190	COG1309	transcriptional regulator
EJC51_RS22195	COG1522	sequence-specific DNA binding
EJC51_RS22200	COG1280	lysine exporter protein (LysE YggA)
EJC51_RS22210	COG1960	acyl-CoA dehydrogenase activity
EJC51_RS22225	COG0259	pyridoxamine-phosphate oxidase activity
EJC51_RS22245	COG2072	flavoprotein involved in K transport
EJC51_RS22250	COG1231	oxidoreductase activity
EJC51_RS22260	COG1024	Enoyl-CoA hydratase
EJC51_RS22290	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
EJC51_RS22295	COG1960	acyl-CoA dehydrogenase activity
EJC51_RS22300	COG1028	Short-chain dehydrogenase reductase Sdr
EJC51_RS22320	COG1960	acyl-CoA dehydrogenase activity
EJC51_RS22325	COG1960	acyl-CoA dehydrogenase activity
EJC51_RS22335	COG0318	PFAM AMP-dependent synthetase and ligase
EJC51_RS22400	COG2945	thiolester hydrolase activity
EJC51_RS22400	COG0596	Alpha beta hydrolase
EJC51_RS22410	COG4821	SIS domain
EJC51_RS22425	COG0583	DNA-binding transcription factor activity
EJC51_RS22455	COG0259	pyridoxamine-phosphate oxidase activity
EJC51_RS22470	COG0318	PFAM AMP-dependent synthetase and ligase
EJC51_RS22485	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EJC51_RS22515	COG0277	FAD linked oxidase domain protein
EJC51_RS22515	COG0247	lactate metabolic process
EJC51_RS22540	COG2124	cytochrome p450
EJC51_RS22550	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EJC51_RS22565	COG1733	regulation of RNA biosynthetic process
EJC51_RS22570	COG0596	Alpha beta hydrolase
EJC51_RS22575	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EJC51_RS22615	COG0667	Aldo Keto reductase
EJC51_RS22645	COG2252	PERMEase
EJC51_RS22655	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EJC51_RS22690	COG2814	Major facilitator Superfamily
EJC51_RS22700	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EJC51_RS22705	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
EJC51_RS22710	COG1278	Cold shock
EJC51_RS22740	COG1061	Type III restriction enzyme res subunit
EJC51_RS22750	COG3973	AAA domain
EJC51_RS22785	COG1737	Transcriptional regulator
EJC51_RS22790	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EJC51_RS22795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EJC51_RS22795	COG1263	PTS System
EJC51_RS22805	COG2318	DinB family
EJC51_RS22825	COG0477	Major facilitator Superfamily
EJC51_RS22830	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EJC51_RS22840	COG0459	protein refolding
EJC51_RS22845	COG1278	Cold shock
EJC51_RS22860	COG0463	Glycosyl transferase, family 2
EJC51_RS22905	COG3300	MHYT domain
EJC51_RS22905	COG5001	Diguanylate cyclase
EJC51_RS22920	COG1595	DNA-templated transcription, initiation
EJC51_RS22925	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EJC51_RS23000	COG1024	Enoyl-CoA hydratase
EJC51_RS23005	COG1024	Enoyl-CoA hydratase
EJC51_RS23010	COG1024	Enoyl-CoA hydratase
EJC51_RS23015	COG3424	synthase
EJC51_RS23025	COG2197	response regulator
EJC51_RS23035	COG1132	(ABC) transporter
EJC51_RS23045	COG0577	efflux transmembrane transporter activity
EJC51_RS23045	COG1136	(ABC) transporter
EJC51_RS23050	COG0577	efflux transmembrane transporter activity
EJC51_RS23050	COG1136	(ABC) transporter
EJC51_RS23055	COG0793	Belongs to the peptidase S41A family
EJC51_RS23055	COG3409	Peptidoglycan-binding domain 1 protein
EJC51_RS23070	COG2124	cytochrome p450
EJC51_RS23085	COG2205	protein histidine kinase activity
EJC51_RS23090	COG0745	RESPONSE REGULATOR receiver
EJC51_RS23095	COG0745	RESPONSE REGULATOR receiver
EJC51_RS23105	COG3842	ATPase activity
EJC51_RS23125	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EJC51_RS23130	COG0215	cysteine-tRNA ligase activity
EJC51_RS23135	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EJC51_RS23140	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EJC51_RS23145	COG1329	Transcriptional regulator
EJC51_RS23165	COG5002	protein histidine kinase activity
EJC51_RS23185	COG0222	ribosome binding
EJC51_RS23190	COG0588	phosphoglycerate mutase activity
EJC51_RS23210	COG2207	Transcriptional regulator
EJC51_RS23210	COG1917	Cupin 2, conserved barrel domain protein
EJC51_RS23225	COG0438	transferase activity, transferring glycosyl groups
EJC51_RS23230	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EJC51_RS23260	COG2226	methyltransferase
EJC51_RS23305	COG2188	Transcriptional regulator
EJC51_RS23315	COG4552	Acetyltransferase involved in intracellular survival and related
EJC51_RS23325	COG1490	D-aminoacyl-tRNA deacylase activity
EJC51_RS23335	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EJC51_RS23345	COG3485	protocatechuate 3,4-dioxygenase
EJC51_RS23390	COG2897	thiosulfate sulfurtransferase activity
EJC51_RS23415	COG0745	RESPONSE REGULATOR receiver
EJC51_RS23420	COG1609	Transcriptional regulator
EJC51_RS23425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EJC51_RS23430	COG0745	RESPONSE REGULATOR receiver
EJC51_RS23450	COG0737	Belongs to the 5'-nucleotidase family
EJC51_RS23455	COG0456	acetyltransferase
EJC51_RS23485	COG1725	Transcriptional regulator
EJC51_RS23490	COG1131	(ABC) transporter
EJC51_RS23510	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EJC51_RS23540	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EJC51_RS23545	COG0306	phosphate transporter
EJC51_RS23555	COG1937	Protein conserved in bacteria
EJC51_RS23570	COG0277	FAD linked oxidase domain protein
EJC51_RS23575	COG0671	phosphoesterase, PA-phosphatase related
EJC51_RS23580	COG0741	lytic transglycosylase activity
EJC51_RS23580	COG0739	heme binding
EJC51_RS23580	COG1196	nuclear chromosome segregation
EJC51_RS23590	COG0300	oxidoreductase activity
EJC51_RS23685	COG1252	NADH dehydrogenase
EJC51_RS23715	COG0579	oxidoreductase
EJC51_RS23720	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EJC51_RS23730	COG0667	Aldo Keto reductase
EJC51_RS23750	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EJC51_RS23750	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EJC51_RS23760	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EJC51_RS23830	COG1643	Atp-dependent helicase
EJC51_RS23865	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EJC51_RS23885	COG1309	transcriptional regulator
EJC51_RS23895	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EJC51_RS23900	COG0047	phosphoribosylformylglycinamidine synthase activity
EJC51_RS23905	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EJC51_RS23940	COG2197	response regulator
EJC51_RS23950	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EJC51_RS23965	COG0151	Belongs to the GarS family
EJC51_RS24000	COG3345	alpha-galactosidase
EJC51_RS24050	COG0433	COG0433 Predicted ATPase
EJC51_RS24065	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EJC51_RS24095	COG1191	sigma factor activity
EJC51_RS24100	COG1191	sigma factor activity
EJC51_RS24120	COG0477	Major facilitator Superfamily
EJC51_RS24130	COG3467	pyridoxamine 5'-phosphate
EJC51_RS24140	COG0477	Major facilitator Superfamily
EJC51_RS24145	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EJC51_RS24155	COG2205	protein histidine kinase activity
EJC51_RS24160	COG0745	RESPONSE REGULATOR receiver
EJC51_RS24165	COG2329	Antibiotic biosynthesis monooxygenase
EJC51_RS24220	COG0784	Response regulator, receiver
EJC51_RS24225	COG0318	PFAM AMP-dependent synthetase and ligase
EJC51_RS24230	COG1595	DNA-templated transcription, initiation
EJC51_RS24270	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EJC51_RS24305	COG0006	proline dipeptidase activity
EJC51_RS24310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EJC51_RS24320	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
EJC51_RS24360	COG2837	iron assimilation
EJC51_RS24370	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EJC51_RS24375	COG0561	phosphatase activity
EJC51_RS24410	COG1131	(ABC) transporter
EJC51_RS24425	COG0789	Transcriptional regulator
EJC51_RS24430	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
EJC51_RS24445	COG0561	phosphatase activity
EJC51_RS24450	COG0739	heme binding
EJC51_RS24460	COG4988	ABC transporter
EJC51_RS24465	COG1294	oxidase, subunit
EJC51_RS24470	COG1271	oxidase subunit
EJC51_RS24480	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EJC51_RS24485	COG1609	Transcriptional regulator
EJC51_RS24505	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EJC51_RS24530	COG0662	Cupin 2, conserved barrel domain protein
EJC51_RS24535	COG1950	PFAM Membrane protein of
EJC51_RS24540	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EJC51_RS24545	COG0626	cystathionine gamma-synthase activity
EJC51_RS24575	COG2814	Major facilitator Superfamily
EJC51_RS24595	COG0305	Participates in initiation and elongation during chromosome replication
EJC51_RS24605	COG0359	binds to the 23S rRNA
EJC51_RS24610	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EJC51_RS24615	COG0629	single-stranded DNA binding
EJC51_RS24620	COG0360	Binds together with S18 to 16S ribosomal RNA
EJC51_RS24645	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EJC51_RS24670	COG0617	tRNA 3'-terminal CCA addition
EJC51_RS24685	COG2815	serine threonine protein kinase
EJC51_RS24685	COG0515	serine threonine protein kinase
EJC51_RS24690	COG1595	DNA-templated transcription, initiation
EJC51_RS24700	COG0492	ferredoxin-NADP+ reductase activity
EJC51_RS24705	COG3118	belongs to the thioredoxin family
EJC51_RS24720	COG1192	Involved in chromosome partitioning
EJC51_RS24725	COG0357	Ribosomal RNA small subunit methyltransferase G
EJC51_RS24735	COG0706	membrane insertase activity
EJC51_RS24740	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EJC51_RS24745	COG0594	ribonuclease P activity
EJC51_RS24755	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EJC51_RS24765	COG0592	DNA-directed DNA polymerase activity
EJC51_RS24770	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EJC51_RS24775	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EJC51_RS24780	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
EJC51_RS24785	COG0187	DNA topoisomerase II activity
EJC51_RS24790	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EJC51_RS24805	COG2319	Wd-40 repeat
EJC51_RS24805	COG4249	Peptidase C14 caspase catalytic subunit p20
EJC51_RS24830	COG0515	serine threonine protein kinase
EJC51_RS24845	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EJC51_RS24855	COG2264	protein methyltransferase activity
EJC51_RS24880	COG0662	Cupin 2, conserved barrel domain protein
EJC51_RS24885	COG1960	acyl-CoA dehydrogenase activity
EJC51_RS24895	COG2313	pseudouridylate synthase activity
EJC51_RS24900	COG0546	phosphoglycolate phosphatase activity
EJC51_RS24925	COG0705	Rhomboid family
EJC51_RS24940	COG3764	Sortase (surface protein transpeptidase)
EJC51_RS24955	COG3764	Sortase (surface protein transpeptidase)
EJC51_RS24960	COG3764	Sortase (surface protein transpeptidase)
EJC51_RS24970	COG0515	serine threonine protein kinase
EJC51_RS24980	COG0768	penicillin binding
EJC51_RS24995	COG1716	ATPase activity
EJC51_RS25000	COG1716	ATPase activity
EJC51_RS25010	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EJC51_RS25015	COG1733	regulation of RNA biosynthetic process
EJC51_RS25030	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EJC51_RS25040	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EJC51_RS25045	COG2151	metal-sulfur cluster biosynthetic enzyme
EJC51_RS25050	COG3396	Phenylacetate-CoA oxygenase
EJC51_RS25055	COG3460	Phenylacetate-CoA oxygenase
EJC51_RS25060	COG3396	Phenylacetate-CoA oxygenase
EJC51_RS25085	COG1250	3-hydroxyacyl-CoA dehydrogenase
EJC51_RS25090	COG1309	transcriptional regulator
EJC51_RS25095	COG1522	sequence-specific DNA binding
EJC51_RS25140	COG0604	alcohol dehydrogenase
EJC51_RS25140	COG3321	synthase
EJC51_RS25140	COG1028	Short-chain dehydrogenase reductase Sdr
EJC51_RS25155	COG0508	dehydrogenase complex catalyzes the overall conversion of
EJC51_RS25160	COG0022	dehydrogenase e1 component
EJC51_RS25185	COG0515	serine threonine protein kinase
EJC51_RS25190	COG0515	serine threonine protein kinase
EJC51_RS25255	COG1362	aminopeptidase activity
EJC51_RS25260	COG1960	acyl-CoA dehydrogenase activity
EJC51_RS25280	COG1741	Belongs to the pirin family
EJC51_RS25300	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EJC51_RS25335	COG1181	Belongs to the D-alanine--D-alanine ligase family
EJC51_RS25345	COG4166	transmembrane transport
EJC51_RS25350	COG3486	L-lysine 6-monooxygenase (NADPH) activity
EJC51_RS25370	COG2022	thiamine diphosphate biosynthetic process
EJC51_RS25370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EJC51_RS25375	COG1045	serine acetyltransferase
EJC51_RS25380	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EJC51_RS25380	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EJC51_RS25415	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EJC51_RS25430	COG1289	transmembrane transporter activity
EJC51_RS25440	COG0596	Alpha beta hydrolase
EJC51_RS25445	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EJC51_RS25495	COG4249	Peptidase C14 caspase catalytic subunit p20
EJC51_RS25495	COG2319	Wd-40 repeat
EJC51_RS25515	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EJC51_RS25520	COG1957	nucleoside hydrolase
EJC51_RS25530	COG0366	Alpha amylase catalytic
EJC51_RS25570	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EJC51_RS25585	COG4213	ABC transporter substrate-binding protein
EJC51_RS25590	COG1595	DNA-templated transcription, initiation
EJC51_RS25595	COG1252	NADH dehydrogenase
EJC51_RS25630	COG4977	sequence-specific DNA binding
EJC51_RS25645	COG2764	glyoxalase bleomycin resistance protein dioxygenase
EJC51_RS25680	COG1309	transcriptional regulator
EJC51_RS25700	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EJC51_RS25720	COG1309	transcriptional regulator
EJC51_RS25790	COG0745	RESPONSE REGULATOR receiver
EJC51_RS25795	COG5002	protein histidine kinase activity
EJC51_RS25820	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EJC51_RS25850	COG1595	DNA-templated transcription, initiation
EJC51_RS25855	COG1595	DNA-templated transcription, initiation
EJC51_RS25865	COG3693	PFAM glycoside hydrolase, family 10
EJC51_RS25890	COG1278	Cold shock
EJC51_RS25925	COG1278	Cold shock
EJC51_RS26005	COG2201	protein-glutamate methylesterase activity
EJC51_RS26015	COG3509	depolymerase
EJC51_RS26065	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EJC51_RS26090	COG1609	Transcriptional regulator
EJC51_RS26145	COG0717	Belongs to the dCTP deaminase family
EJC51_RS26200	COG3739	integral membrane protein
EJC51_RS26205	COG2181	nitrate reductase activity
EJC51_RS26205	COG0247	lactate metabolic process
EJC51_RS26210	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EJC51_RS26215	COG0443	Heat shock 70 kDa protein
EJC51_RS26220	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EJC51_RS26225	COG0484	heat shock protein binding
EJC51_RS26230	COG0789	Transcriptional regulator
EJC51_RS26245	COG4213	ABC transporter substrate-binding protein
EJC51_RS26255	COG1305	Transglutaminase-like
EJC51_RS26265	COG2308	Evidence 4 Homologs of previously reported genes of
EJC51_RS26300	COG0542	response to heat
EJC51_RS26335	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EJC51_RS26345	COG4585	Histidine kinase
EJC51_RS26350	COG2197	response regulator
EJC51_RS26365	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EJC51_RS26370	COG0191	fructose-bisphosphate aldolase activity
EJC51_RS26375	COG0477	Major facilitator Superfamily
EJC51_RS26390	COG3844	kynureninase activity
EJC51_RS26425	COG4585	Histidine kinase
EJC51_RS26430	COG2197	response regulator
EJC51_RS26435	COG4585	Histidine kinase
EJC51_RS26440	COG2197	response regulator
EJC51_RS26485	COG1309	transcriptional regulator
EJC51_RS26490	COG0667	Aldo Keto reductase
EJC51_RS26505	COG3559	Exporter of polyketide antibiotics
EJC51_RS26510	COG1131	(ABC) transporter
EJC51_RS26530	COG4302	ethanolamine ammonia-lyase activity
EJC51_RS26545	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EJC51_RS26555	COG0737	Belongs to the 5'-nucleotidase family
EJC51_RS26575	COG1802	Transcriptional regulator
EJC51_RS26580	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EJC51_RS26600	COG2197	response regulator
EJC51_RS26605	COG4585	Histidine kinase
EJC51_RS26620	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EJC51_RS26625	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EJC51_RS26640	COG3903	Transcriptional regulator
EJC51_RS26640	COG3629	intracellular signal transduction
EJC51_RS26685	COG2205	protein histidine kinase activity
EJC51_RS26705	COG1595	DNA-templated transcription, initiation
EJC51_RS26735	COG0701	Predicted permease
EJC51_RS26750	COG2249	NAD(P)H dehydrogenase (quinone) activity
EJC51_RS26755	COG4122	O-methyltransferase activity
EJC51_RS26775	COG1408	metallophosphoesterase
EJC51_RS26820	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EJC51_RS26835	COG0003	Pfam Anion-transporting ATPase
EJC51_RS26860	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EJC51_RS26895	COG2267	carboxylic ester hydrolase activity
EJC51_RS26905	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EJC51_RS26910	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EJC51_RS26985	COG1111	helicase
EJC51_RS26985	COG1205	dead DEAH box helicase
EJC51_RS26990	COG1366	Belongs to the anti-sigma-factor antagonist family
EJC51_RS27000	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
EJC51_RS27010	COG2264	protein methyltransferase activity
EJC51_RS27025	COG1754	DNA topoisomerase type I activity
EJC51_RS27025	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EJC51_RS27030	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EJC51_RS27035	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EJC51_RS27085	COG1302	Protein conserved in bacteria
EJC51_RS27150	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EJC51_RS27150	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EJC51_RS27160	COG1280	lysine exporter protein (LysE YggA)
EJC51_RS27180	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EJC51_RS27185	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EJC51_RS27190	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EJC51_RS27195	COG0254	rRNA binding
EJC51_RS27205	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EJC51_RS27245	COG1012	belongs to the aldehyde dehydrogenase family
EJC51_RS27250	COG2318	DinB family
EJC51_RS27270	COG0076	glutamate decarboxylase activity
EJC51_RS27280	COG0789	Transcriptional regulator
EJC51_RS27285	COG0393	Putative heavy-metal-binding
EJC51_RS27300	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EJC51_RS27305	COG2027	D-alanyl-D-alanine carboxypeptidase
EJC51_RS27315	COG0037	tRNA processing
EJC51_RS27330	COG0302	gtp cyclohydrolase
EJC51_RS27345	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EJC51_RS27385	COG0649	NAD binding
EJC51_RS27405	COG1660	Displays ATPase and GTPase activities
EJC51_RS27430	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EJC51_RS27435	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EJC51_RS27445	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EJC51_RS27465	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EJC51_RS27500	COG0739	heme binding
EJC51_RS27505	COG1309	transcriptional regulator
EJC51_RS27510	COG0477	Major facilitator Superfamily
EJC51_RS27515	COG3708	Transcriptional regulator
EJC51_RS27515	COG2207	Transcriptional regulator
EJC51_RS27525	COG2205	protein histidine kinase activity
EJC51_RS27530	COG0745	RESPONSE REGULATOR receiver
EJC51_RS27540	COG1595	DNA-templated transcription, initiation
EJC51_RS27555	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EJC51_RS27580	COG0248	Ppx GppA phosphatase
EJC51_RS27585	COG1082	Xylose isomerase domain protein TIM barrel
EJC51_RS27590	COG1309	transcriptional regulator
EJC51_RS27595	COG0129	dihydroxy-acid dehydratase activity
EJC51_RS27605	COG4991	sh3 domain protein
EJC51_RS27610	COG4991	sh3 domain protein
EJC51_RS27635	COG1129	ABC transporter
EJC51_RS27635	COG0842	Transport permease protein
EJC51_RS27645	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EJC51_RS27650	COG0180	Tryptophanyl-tRNA synthetase
EJC51_RS27675	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EJC51_RS27685	COG0738	Major facilitator superfamily
EJC51_RS27690	COG0123	including yeast histone deacetylase and acetoin utilization protein
EJC51_RS27745	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EJC51_RS27750	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EJC51_RS27755	COG0181	hydroxymethylbilane synthase activity
EJC51_RS27760	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EJC51_RS27760	COG1648	precorrin-2 dehydrogenase activity
EJC51_RS27780	COG0113	porphobilinogen synthase activity
EJC51_RS27800	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EJC51_RS27835	COG0018	arginyl-trna synthetase
EJC51_RS27840	COG2133	pyrroloquinoline quinone binding
EJC51_RS27840	COG5183	chlorophyll binding
EJC51_RS27845	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
EJC51_RS27865	COG1690	Belongs to the RtcB family
EJC51_RS27885	COG1742	UPF0060 membrane protein
EJC51_RS27895	COG1846	Transcriptional regulator
EJC51_RS27900	COG1733	regulation of RNA biosynthetic process
EJC51_RS27910	COG0477	Major facilitator Superfamily
EJC51_RS27920	COG1276	copper resistance
EJC51_RS27925	COG3794	PFAM blue (type 1) copper domain protein
EJC51_RS27940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EJC51_RS27950	COG0745	RESPONSE REGULATOR receiver
EJC51_RS27985	COG2264	protein methyltransferase activity
EJC51_RS27995	COG0723	plastoquinol--plastocyanin reductase activity
EJC51_RS27995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EJC51_RS28010	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EJC51_RS28015	COG0640	Transcriptional regulator
EJC51_RS28025	COG0640	Transcriptional regulator
EJC51_RS28040	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EJC51_RS28045	COG0406	alpha-ribazole phosphatase activity
EJC51_RS28055	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EJC51_RS28060	COG0785	Cytochrome C biogenesis protein
EJC51_RS28065	COG1333	cytochrome c biogenesis protein
EJC51_RS28070	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EJC51_RS28095	COG0137	argininosuccinate synthase activity
EJC51_RS28105	COG0640	Transcriptional regulator
EJC51_RS28120	COG0697	spore germination
EJC51_RS28125	COG0583	DNA-binding transcription factor activity
EJC51_RS28135	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EJC51_RS28140	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EJC51_RS28145	COG0163	prenyltransferase activity
EJC51_RS28155	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
EJC51_RS28160	COG1573	uracil-dna glycosylase
EJC51_RS28185	COG1309	transcriptional regulator
EJC51_RS28205	COG0183	Belongs to the thiolase family
EJC51_RS28215	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EJC51_RS28250	COG1053	succinate dehydrogenase
EJC51_RS28255	COG4106	trans-aconitate 2-methyltransferase activity
EJC51_RS28270	COG1396	sequence-specific DNA binding
EJC51_RS28275	COG1278	Cold shock
EJC51_RS28280	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
EJC51_RS28385	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
EJC51_RS28480	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
EJC51_RS28495	COG2226	methyltransferase
EJC51_RS28515	COG0242	peptide deformylase activity
EJC51_RS28530	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EJC51_RS28535	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EJC51_RS28540	COG0649	NAD binding
EJC51_RS28550	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EJC51_RS28555	COG1034	ATP synthesis coupled electron transport
EJC51_RS28560	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EJC51_RS28565	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EJC51_RS28570	COG0839	Belongs to the complex I subunit 6 family
EJC51_RS28575	COG0713	ATP synthesis coupled electron transport
EJC51_RS28580	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EJC51_RS28590	COG1007	ATP synthesis coupled electron transport
EJC51_RS28600	COG0514	ATP-dependent DNA helicase (RecQ)
EJC51_RS28605	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EJC51_RS28610	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EJC51_RS28615	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EJC51_RS28630	COG2188	Transcriptional regulator
EJC51_RS28650	COG0492	ferredoxin-NADP+ reductase activity
EJC51_RS28660	COG0561	phosphatase activity
EJC51_RS28675	COG3104	oligopeptide transport
EJC51_RS28680	COG0142	geranyltranstransferase activity
EJC51_RS28705	COG0655	NAD(P)H dehydrogenase (quinone) activity
EJC51_RS28735	COG0702	epimerase
EJC51_RS28740	COG1733	regulation of RNA biosynthetic process
EJC51_RS28750	COG1013	pyruvate-flavodoxin oxidoreductase activity
EJC51_RS28755	COG0674	pyruvate-flavodoxin oxidoreductase activity
EJC51_RS28755	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EJC51_RS28780	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EJC51_RS28785	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EJC51_RS28790	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EJC51_RS28795	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EJC51_RS28800	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EJC51_RS28810	COG0713	ATP synthesis coupled electron transport
EJC51_RS28815	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EJC51_RS28825	COG1007	ATP synthesis coupled electron transport
EJC51_RS28830	COG0501	Belongs to the peptidase M48B family
EJC51_RS28835	COG3304	Inner membrane component domain
EJC51_RS28850	COG2261	transglycosylase associated protein
EJC51_RS28855	COG1666	GTP binding
EJC51_RS28870	COG0702	epimerase
EJC51_RS28890	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EJC51_RS28895	COG2030	dehydratase
EJC51_RS28915	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EJC51_RS28935	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EJC51_RS28940	COG0436	Aminotransferase
EJC51_RS28955	COG0250	Participates in transcription elongation, termination and antitermination
EJC51_RS28970	COG0081	regulation of translation
EJC51_RS28985	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EJC51_RS28990	COG0222	ribosome binding
EJC51_RS29000	COG0085	RNA polymerase activity
EJC51_RS29005	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EJC51_RS29015	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EJC51_RS29020	COG0049	tRNA binding
EJC51_RS29025	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EJC51_RS29095	COG0051	transcription antitermination factor activity, RNA binding
EJC51_RS29100	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EJC51_RS29105	COG0088	Forms part of the polypeptide exit tunnel
EJC51_RS29110	COG0089	rRNA binding
EJC51_RS29115	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EJC51_RS29120	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EJC51_RS29125	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EJC51_RS29130	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EJC51_RS29135	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EJC51_RS29140	COG0255	Belongs to the universal ribosomal protein uL29 family
EJC51_RS29145	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EJC51_RS29150	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EJC51_RS29155	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EJC51_RS29160	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EJC51_RS29165	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EJC51_RS29175	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EJC51_RS29180	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EJC51_RS29185	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EJC51_RS29190	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EJC51_RS29195	COG1841	ribosomal large subunit assembly
EJC51_RS29200	COG0200	Binds to the 23S rRNA
EJC51_RS29210	COG0563	adenylate kinase activity
EJC51_RS29220	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EJC51_RS29225	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EJC51_RS29230	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EJC51_RS29235	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EJC51_RS29240	COG0202	RNA polymerase activity
EJC51_RS29245	COG0203	ribosomal protein L17
EJC51_RS29250	COG0101	tRNA pseudouridine synthase activity
EJC51_RS29260	COG1215	transferase activity, transferring glycosyl groups
EJC51_RS29295	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EJC51_RS29300	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EJC51_RS29305	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EJC51_RS29315	COG1072	(Pantothenic acid kinase))
EJC51_RS29320	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EJC51_RS29325	COG0736	holo-[acyl-carrier-protein] synthase activity
EJC51_RS29345	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EJC51_RS29355	COG0802	atpase or kinase
EJC51_RS29375	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EJC51_RS29395	COG1609	Transcriptional regulator
EJC51_RS29415	COG4941	Belongs to the sigma-70 factor family
EJC51_RS29430	COG0726	polysaccharide deacetylase
EJC51_RS29435	COG0726	polysaccharide deacetylase
EJC51_RS29445	COG0459	protein refolding
EJC51_RS29465	COG1181	Belongs to the D-alanine--D-alanine ligase family
EJC51_RS29475	COG4221	oxidoreductase activity
EJC51_RS29480	COG1834	amidinotransferase
EJC51_RS29505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EJC51_RS29515	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EJC51_RS29525	COG4221	oxidoreductase activity
EJC51_RS29535	COG0583	DNA-binding transcription factor activity
EJC51_RS29550	COG1595	DNA-templated transcription, initiation
EJC51_RS29560	COG0516	GMP reductase activity
EJC51_RS29570	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EJC51_RS29585	COG0515	serine threonine protein kinase
EJC51_RS29585	COG2815	serine threonine protein kinase
EJC51_RS29590	COG2815	serine threonine protein kinase
EJC51_RS29590	COG0515	serine threonine protein kinase
EJC51_RS29605	COG0515	serine threonine protein kinase
EJC51_RS29615	COG1012	belongs to the aldehyde dehydrogenase family
EJC51_RS29640	COG0519	Catalyzes the synthesis of GMP from XMP
EJC51_RS29640	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EJC51_RS29700	COG2197	response regulator
EJC51_RS29725	COG2319	Wd-40 repeat
EJC51_RS29725	COG4249	Peptidase C14 caspase catalytic subunit p20
EJC51_RS29735	COG0791	NLP P60 protein
EJC51_RS29755	COG0210	DNA helicase
EJC51_RS29770	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EJC51_RS29770	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EJC51_RS29790	COG0714	Associated with various cellular activities
EJC51_RS29795	COG2425	protein containing a von Willebrand factor type A (vWA) domain
EJC51_RS29805	COG3552	Protein containing von Willebrand factor type A (VWA) domain
EJC51_RS29825	COG0045	succinate-CoA ligase (ADP-forming) activity
EJC51_RS29855	COG0138	bifunctional purine biosynthesis protein purh
EJC51_RS29865	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EJC51_RS29885	COG0039	L-malate dehydrogenase activity
EJC51_RS29895	COG0477	Major facilitator Superfamily
EJC51_RS29915	COG2318	DinB family
EJC51_RS29925	COG1012	belongs to the aldehyde dehydrogenase family
EJC51_RS29935	COG0517	IMP dehydrogenase activity
EJC51_RS29935	COG4175	Glycine betaine
EJC51_RS29955	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EJC51_RS29960	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EJC51_RS29965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EJC51_RS29980	COG0754	glutathionylspermidine amidase activity
EJC51_RS29985	COG2226	methyltransferase
EJC51_RS29990	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EJC51_RS29995	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EJC51_RS30015	COG0180	Tryptophanyl-tRNA synthetase
EJC51_RS30035	COG0671	phosphoesterase, PA-phosphatase related
EJC51_RS30040	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EJC51_RS30045	COG1295	ribonuclease BN
EJC51_RS30060	COG1408	metallophosphoesterase
EJC51_RS30075	COG2205	protein histidine kinase activity
EJC51_RS30080	COG0745	RESPONSE REGULATOR receiver
EJC51_RS30085	COG2409	Drug exporters of the RND superfamily
EJC51_RS30090	COG1309	transcriptional regulator
EJC51_RS30120	COG1053	succinate dehydrogenase
EJC51_RS30130	COG2009	succinate dehydrogenase
EJC51_RS30190	COG1595	DNA-templated transcription, initiation
EJC51_RS30205	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EJC51_RS30205	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EJC51_RS30230	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EJC51_RS30260	COG1216	Glycosyl transferase, family 2
EJC51_RS30275	COG2089	acid synthase
EJC51_RS30300	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
EJC51_RS30300	COG1473	amidohydrolase
EJC51_RS30305	COG1744	ABC transporter substrate-binding protein PnrA-like
EJC51_RS30310	COG1744	ABC transporter substrate-binding protein PnrA-like
EJC51_RS30315	COG3845	ABC transporter
EJC51_RS30325	COG1079	Belongs to the binding-protein-dependent transport system permease family
EJC51_RS30360	COG2814	Major facilitator Superfamily
EJC51_RS30365	COG0583	DNA-binding transcription factor activity
EJC51_RS30375	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EJC51_RS30400	COG2205	protein histidine kinase activity
EJC51_RS30405	COG0745	RESPONSE REGULATOR receiver
EJC51_RS30410	COG1595	DNA-templated transcription, initiation
EJC51_RS30430	COG1012	belongs to the aldehyde dehydrogenase family
EJC51_RS30435	COG1012	belongs to the aldehyde dehydrogenase family
EJC51_RS30460	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EJC51_RS30500	COG4770	biotin carboxylase activity
EJC51_RS30510	COG0424	maF-like protein
EJC51_RS30530	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EJC51_RS30540	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
EJC51_RS30550	COG1024	Enoyl-CoA hydratase
EJC51_RS30560	COG2986	histidine ammonia-lyase
EJC51_RS30585	COG1404	Belongs to the peptidase S8 family
EJC51_RS30595	COG1136	(ABC) transporter
EJC51_RS30615	COG1064	alcohol dehydrogenase
EJC51_RS30625	COG2304	oxidoreductase activity
EJC51_RS30635	COG0702	epimerase
EJC51_RS30640	COG2188	Transcriptional regulator
EJC51_RS30660	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EJC51_RS30680	COG1595	DNA-templated transcription, initiation
EJC51_RS30685	COG2255	four-way junction helicase activity
EJC51_RS30690	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EJC51_RS30705	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EJC51_RS30715	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EJC51_RS30735	COG1331	Highly conserved protein containing a thioredoxin domain
EJC51_RS30765	COG1309	transcriptional regulator
EJC51_RS30770	COG0477	Major facilitator Superfamily
EJC51_RS30780	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
EJC51_RS30785	COG0515	serine threonine protein kinase
EJC51_RS30785	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EJC51_RS30855	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
EJC51_RS30870	COG1414	Transcriptional regulator
EJC51_RS30875	COG0251	oxidation-reduction process
EJC51_RS30880	COG2610	gluconate transmembrane transporter activity
EJC51_RS30905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EJC51_RS30935	COG1595	DNA-templated transcription, initiation
EJC51_RS30950	COG1819	glycosyl
EJC51_RS30955	COG3973	AAA domain
EJC51_RS30980	COG2894	cell division
EJC51_RS31010	COG3920	Histidine kinase
EJC51_RS31015	COG2197	response regulator
EJC51_RS31105	COG2318	DinB family
EJC51_RS31115	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EJC51_RS31125	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EJC51_RS31130	COG0741	lytic transglycosylase activity
EJC51_RS31140	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EJC51_RS31145	COG0450	alkyl hydroperoxide reductase
EJC51_RS31175	COG1136	(ABC) transporter
EJC51_RS31195	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EJC51_RS31210	COG0114	fumarate hydratase activity
EJC51_RS31215	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EJC51_RS31215	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EJC51_RS31240	COG0778	Nitroreductase
EJC51_RS31245	COG1722	exodeoxyribonuclease VII activity
EJC51_RS31250	COG1570	exodeoxyribonuclease VII activity
EJC51_RS31260	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EJC51_RS31275	COG0012	GTP binding
EJC51_RS31295	COG0745	RESPONSE REGULATOR receiver
EJC51_RS31300	COG1309	transcriptional regulator
EJC51_RS31305	COG0477	Major facilitator Superfamily
EJC51_RS31325	COG0745	RESPONSE REGULATOR receiver
EJC51_RS31360	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EJC51_RS31390	COG0583	DNA-binding transcription factor activity
EJC51_RS31450	COG1053	succinate dehydrogenase
EJC51_RS31475	COG1217	gtp-binding protein TYPA
EJC51_RS31480	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EJC51_RS31485	COG4166	transmembrane transport
EJC51_RS31490	COG0601	transmembrane transport
EJC51_RS31495	COG0444	Belongs to the ABC transporter superfamily
EJC51_RS31500	COG4608	Belongs to the ABC transporter superfamily
EJC51_RS31515	COG3629	intracellular signal transduction
EJC51_RS31530	COG0346	lactoylglutathione lyase activity
EJC51_RS31535	COG2318	DinB family
EJC51_RS31540	COG4608	Belongs to the ABC transporter superfamily
EJC51_RS31545	COG0444	Belongs to the ABC transporter superfamily
EJC51_RS31550	COG0601	transmembrane transport
EJC51_RS31555	COG0747	negative chemotaxis
EJC51_RS31560	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EJC51_RS31570	COG0601	transmembrane transport
EJC51_RS31575	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EJC51_RS31585	COG4608	Belongs to the ABC transporter superfamily
EJC51_RS31600	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EJC51_RS31615	COG1131	(ABC) transporter
EJC51_RS31625	COG4585	Histidine kinase
EJC51_RS31630	COG2197	response regulator
EJC51_RS31665	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EJC51_RS31675	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EJC51_RS31685	COG2818	Glycosylase
EJC51_RS31690	COG1024	Enoyl-CoA hydratase
EJC51_RS31705	COG1595	DNA-templated transcription, initiation
EJC51_RS31715	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EJC51_RS31720	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EJC51_RS31755	COG0598	Magnesium transport protein CorA
EJC51_RS31765	COG2814	Major facilitator Superfamily
EJC51_RS31780	COG2095	MarC family integral membrane protein
EJC51_RS31790	COG1432	Conserved Protein
EJC51_RS31845	COG0747	negative chemotaxis
EJC51_RS31850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EJC51_RS31915	COG0210	DNA helicase
EJC51_RS31920	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EJC51_RS31960	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EJC51_RS32010	COG3480	Lon protease (S16) C-terminal proteolytic domain
EJC51_RS32020	COG1615	UPF0182 protein
EJC51_RS32065	COG0483	inositol monophosphate 1-phosphatase activity
EJC51_RS32075	COG2076	Multidrug Resistance protein
EJC51_RS32085	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EJC51_RS32095	COG2135	peptidase activity
EJC51_RS32105	COG1595	DNA-templated transcription, initiation
EJC51_RS32110	COG5662	AntiSigma factor
EJC51_RS32115	COG2199	diguanylate cyclase activity
EJC51_RS32115	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
EJC51_RS32130	COG0242	peptide deformylase activity
EJC51_RS32140	COG2124	cytochrome p450
EJC51_RS32190	COG1966	Carbon starvation protein
EJC51_RS32195	COG2188	Transcriptional regulator
EJC51_RS32200	COG2182	Extracellular solute-binding protein
EJC51_RS32205	COG1175	transmembrane transport
EJC51_RS32210	COG0395	ABC-type sugar transport system, permease component
EJC51_RS32215	COG1472	Belongs to the glycosyl hydrolase 3 family
EJC51_RS32220	COG0363	glucosamine-6-phosphate deaminase activity
EJC51_RS32225	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EJC51_RS32230	COG1028	Short-chain dehydrogenase reductase Sdr
EJC51_RS32250	COG1597	lipid kinase activity
EJC51_RS32280	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EJC51_RS32290	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EJC51_RS32295	COG0142	geranyltranstransferase activity
EJC51_RS32325	COG4941	Belongs to the sigma-70 factor family
EJC51_RS32380	COG4106	trans-aconitate 2-methyltransferase activity
EJC51_RS32385	COG1126	abc transporter atp-binding protein
EJC51_RS32390	COG0765	amino acid transport
EJC51_RS32405	COG0281	malic enzyme
EJC51_RS32410	COG0604	alcohol dehydrogenase
EJC51_RS32455	COG0567	Dehydrogenase, E1 component
EJC51_RS32455	COG0508	dehydrogenase complex catalyzes the overall conversion of
EJC51_RS32460	COG2205	protein histidine kinase activity
EJC51_RS32465	COG0745	RESPONSE REGULATOR receiver
EJC51_RS32500	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EJC51_RS32590	COG0772	Belongs to the SEDS family
EJC51_RS32600	COG2205	protein histidine kinase activity
EJC51_RS32625	COG1793	dna ligase
EJC51_RS32625	COG3285	dna ligase
EJC51_RS32630	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EJC51_RS32635	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EJC51_RS32725	COG0270	DNA (cytosine-5-)-methyltransferase activity
EJC51_RS32760	COG0745	RESPONSE REGULATOR receiver
EJC51_RS32765	COG0018	arginyl-trna synthetase
EJC51_RS32770	COG0019	diaminopimelate decarboxylase activity
EJC51_RS32775	COG0460	homoserine dehydrogenase
EJC51_RS32780	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EJC51_RS32785	COG0083	homoserine kinase activity
EJC51_RS32805	COG0254	rRNA binding
EJC51_RS32810	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EJC51_RS32815	COG2890	protein-(glutamine-N5) methyltransferase activity
EJC51_RS32825	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EJC51_RS32830	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EJC51_RS32850	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EJC51_RS32855	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EJC51_RS32860	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EJC51_RS32865	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EJC51_RS32870	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EJC51_RS32875	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EJC51_RS32880	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EJC51_RS32895	COG2197	response regulator
EJC51_RS32900	COG4585	Histidine kinase
EJC51_RS32930	COG1250	3-hydroxyacyl-CoA dehydrogenase
EJC51_RS32945	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
EJC51_RS32980	COG1131	(ABC) transporter
EJC51_RS33000	COG0346	lactoylglutathione lyase activity
EJC51_RS33005	COG0183	Belongs to the thiolase family
EJC51_RS33025	COG0745	RESPONSE REGULATOR receiver
EJC51_RS33030	COG2205	protein histidine kinase activity
EJC51_RS33120	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EJC51_RS33120	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EJC51_RS33155	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EJC51_RS33160	COG0857	belongs to the CobB CobQ family
EJC51_RS33160	COG0280	phosphate acetyltransferase
EJC51_RS33165	COG0205	6-phosphofructokinase activity
EJC51_RS33175	COG0395	ABC-type sugar transport system, permease component
EJC51_RS33180	COG1175	transmembrane transport
EJC51_RS33190	COG3629	intracellular signal transduction
EJC51_RS33190	COG3903	Transcriptional regulator
EJC51_RS33195	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EJC51_RS33215	COG3629	intracellular signal transduction
EJC51_RS33215	COG3903	Transcriptional regulator
EJC51_RS33220	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EJC51_RS33240	COG3290	protein histidine kinase activity
EJC51_RS33245	COG1301	dicarboxylic acid transport
EJC51_RS33275	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EJC51_RS33280	COG0667	Aldo Keto reductase
EJC51_RS33290	COG1522	sequence-specific DNA binding
EJC51_RS33315	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EJC51_RS33320	COG3281	Trehalose synthase
EJC51_RS33330	COG0366	Alpha amylase catalytic
EJC51_RS33340	COG0058	SHG alpha-glucan phosphorylase activity
EJC51_RS33360	COG1132	(ABC) transporter
EJC51_RS33365	COG1132	(ABC) transporter
EJC51_RS33370	COG1132	(ABC) transporter
EJC51_RS33375	COG1132	(ABC) transporter
EJC51_RS33380	COG1131	(ABC) transporter
EJC51_RS33395	COG2197	response regulator
EJC51_RS33400	COG3119	arylsulfatase activity
EJC51_RS33410	COG1376	ErfK ybiS ycfS ynhG family protein
EJC51_RS33415	COG1376	ErfK ybiS ycfS ynhG family protein
EJC51_RS33450	COG0789	Transcriptional regulator
EJC51_RS33465	COG0604	alcohol dehydrogenase
EJC51_RS33470	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EJC51_RS33480	COG3409	Peptidoglycan-binding domain 1 protein
EJC51_RS33480	COG3757	hydrolase, family 25
EJC51_RS33485	COG1760	l-serine dehydratase
EJC51_RS33490	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EJC51_RS33495	COG0509	glycine decarboxylation via glycine cleavage system
EJC51_RS33500	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EJC51_RS33520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EJC51_RS33525	COG4166	transmembrane transport
EJC51_RS33535	COG0444	Belongs to the ABC transporter superfamily
EJC51_RS33540	COG4608	Belongs to the ABC transporter superfamily
EJC51_RS33550	COG2860	membrane
EJC51_RS33595	COG3023	N-Acetylmuramoyl-L-alanine amidase
EJC51_RS33600	COG0482	sulfurtransferase activity
EJC51_RS33615	COG1611	Belongs to the LOG family
EJC51_RS33620	COG4221	oxidoreductase activity
EJC51_RS33630	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EJC51_RS33640	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EJC51_RS33645	COG0154	amidase activity
EJC51_RS33655	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EJC51_RS33670	COG2409	Drug exporters of the RND superfamily
EJC51_RS33675	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EJC51_RS33690	COG1672	PFAM Archaeal ATPase
EJC51_RS33690	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
EJC51_RS33700	COG2133	pyrroloquinoline quinone binding
EJC51_RS33705	COG0667	Aldo Keto reductase
EJC51_RS33715	COG3300	MHYT domain
EJC51_RS33715	COG5001	Diguanylate cyclase
EJC51_RS33725	COG0440	acetolactate synthase activity
EJC51_RS33730	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EJC51_RS33735	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EJC51_RS33740	COG0477	Major facilitator Superfamily
EJC51_RS33750	COG4608	Belongs to the ABC transporter superfamily
EJC51_RS33760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EJC51_RS33765	COG0747	negative chemotaxis
EJC51_RS33770	COG3835	regulator
EJC51_RS33775	COG0506	proline dehydrogenase activity
EJC51_RS33780	COG1012	belongs to the aldehyde dehydrogenase family
EJC51_RS33795	COG0583	DNA-binding transcription factor activity
EJC51_RS33810	COG0473	3-isopropylmalate dehydrogenase activity
EJC51_RS33815	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EJC51_RS33825	COG0831	urea catabolic process
EJC51_RS33825	COG0832	Belongs to the urease beta subunit family
EJC51_RS33830	COG0804	urea catabolic process
EJC51_RS33835	COG2957	Belongs to the agmatine deiminase family
EJC51_RS33865	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EJC51_RS33900	COG2353	YceI-like domain
EJC51_RS33905	COG5492	domain, Protein
EJC51_RS33910	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EJC51_RS33930	COG2018	Roadblock/LC7 domain
EJC51_RS33950	COG2018	Roadblock/LC7 domain
EJC51_RS33955	COG5002	protein histidine kinase activity
EJC51_RS33965	COG0179	Fumarylacetoacetate (FAA) hydrolase
EJC51_RS33970	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EJC51_RS34015	COG1414	Transcriptional regulator
EJC51_RS34020	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EJC51_RS34025	COG0066	3-isopropylmalate dehydratase activity
EJC51_RS34035	COG0776	regulation of translation
EJC51_RS34045	COG1920	GTP binding
EJC51_RS34055	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EJC51_RS34060	COG1181	Belongs to the D-alanine--D-alanine ligase family
EJC51_RS34080	COG0351	phosphomethylpyrimidine kinase
EJC51_RS34085	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EJC51_RS34090	COG1461	Dihydroxyacetone kinase
EJC51_RS34100	COG0326	Molecular chaperone. Has ATPase activity
EJC51_RS34110	COG0742	ribosomal rna small subunit methyltransferase
EJC51_RS34115	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EJC51_RS34130	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EJC51_RS34135	COG0571	ribonuclease III activity
EJC51_RS34140	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EJC51_RS34145	COG1733	regulation of RNA biosynthetic process
EJC51_RS34150	COG0655	NAD(P)H dehydrogenase (quinone) activity
EJC51_RS34155	COG2340	Cysteine-rich secretory protein family
EJC51_RS34160	COG1254	Belongs to the acylphosphatase family
EJC51_RS34175	COG1196	nuclear chromosome segregation
EJC51_RS34180	COG0477	Major facilitator Superfamily
EJC51_RS34215	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
EJC51_RS34225	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EJC51_RS34240	COG0228	four-way junction DNA binding
EJC51_RS34245	COG1837	Belongs to the UPF0109 family
EJC51_RS34250	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EJC51_RS34255	COG0336	Belongs to the RNA methyltransferase TrmD family
EJC51_RS34260	COG0335	large ribosomal subunit rRNA binding
EJC51_RS34270	COG0681	Belongs to the peptidase S26 family
EJC51_RS34295	COG0792	nuclease activity
EJC51_RS34310	COG1191	sigma factor activity
EJC51_RS34320	COG4942	peptidase
EJC51_RS34325	COG0052	Belongs to the universal ribosomal protein uS2 family
EJC51_RS34330	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EJC51_RS34335	COG0528	UMP kinase activity
EJC51_RS34340	COG0233	cytoplasmic translational termination
EJC51_RS34345	COG0575	Belongs to the CDS family
EJC51_RS34360	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EJC51_RS34370	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EJC51_RS34375	COG3842	ATPase activity
EJC51_RS34405	COG1136	(ABC) transporter
EJC51_RS34410	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EJC51_RS34420	COG1012	belongs to the aldehyde dehydrogenase family
EJC51_RS34445	COG1595	DNA-templated transcription, initiation
EJC51_RS34460	COG0584	glycerophosphoryl diester phosphodiesterase
EJC51_RS34465	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EJC51_RS34490	COG3842	ATPase activity
EJC51_RS34495	COG1176	ABC-type spermidine putrescine transport system, permease component I
EJC51_RS34500	COG1177	transmembrane transport
EJC51_RS34505	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EJC51_RS34515	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EJC51_RS34545	COG1012	belongs to the aldehyde dehydrogenase family
EJC51_RS34560	COG1653	transport
EJC51_RS34565	COG4209	transmembrane transport
EJC51_RS34570	COG0395	ABC-type sugar transport system, permease component
EJC51_RS34615	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EJC51_RS34620	COG0750	zinc metalloprotease
EJC51_RS34625	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EJC51_RS34640	COG0442	prolyl-tRNA aminoacylation
EJC51_RS34655	COG1595	DNA-templated transcription, initiation
EJC51_RS34695	COG0779	Required for maturation of 30S ribosomal subunits
EJC51_RS34710	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EJC51_RS34720	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EJC51_RS34725	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EJC51_RS34755	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EJC51_RS34760	COG1185	polyribonucleotide nucleotidyltransferase activity
EJC51_RS34765	COG0612	Peptidase, M16
EJC51_RS34770	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EJC51_RS34790	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
EJC51_RS34795	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EJC51_RS34800	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EJC51_RS34835	COG2208	phosphoserine phosphatase activity
EJC51_RS34835	COG2770	Histidine kinase
EJC51_RS34845	COG2205	protein histidine kinase activity
EJC51_RS34845	COG3437	response regulator, receiver
EJC51_RS34845	COG3850	Histidine kinase
EJC51_RS34845	COG4999	Histidine kinase
EJC51_RS34855	COG1674	ftsk spoiiie
EJC51_RS34865	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EJC51_RS34875	COG1546	Belongs to the CinA family
EJC51_RS34875	COG1058	Belongs to the CinA family
EJC51_RS34880	COG1396	sequence-specific DNA binding
EJC51_RS34885	COG0783	Belongs to the Dps family
EJC51_RS34900	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EJC51_RS34905	COG1201	RNA secondary structure unwinding
EJC51_RS34910	COG2207	Transcriptional regulator
EJC51_RS34935	COG0628	permease
EJC51_RS34945	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EJC51_RS34965	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EJC51_RS34970	COG0765	amino acid transport
EJC51_RS34975	COG0765	amino acid transport
EJC51_RS34980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EJC51_RS34985	COG1126	abc transporter atp-binding protein
EJC51_RS34990	COG0745	RESPONSE REGULATOR receiver
EJC51_RS34995	COG2205	protein histidine kinase activity
EJC51_RS35000	COG2358	TRAP transporter, solute receptor (TAXI family
EJC51_RS35025	COG2197	response regulator
EJC51_RS35040	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EJC51_RS35060	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EJC51_RS35070	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EJC51_RS35075	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EJC51_RS35085	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EJC51_RS35120	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EJC51_RS35125	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EJC51_RS35130	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EJC51_RS35170	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EJC51_RS35185	COG0514	ATP-dependent DNA helicase (RecQ)
EJC51_RS35210	COG1802	Transcriptional regulator
EJC51_RS35215	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EJC51_RS35230	COG0187	DNA topoisomerase II activity
EJC51_RS35255	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EJC51_RS35260	COG4565	transcriptional regulatory protein
EJC51_RS35270	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EJC51_RS35280	COG4565	transcriptional regulatory protein
EJC51_RS35285	COG3290	protein histidine kinase activity
EJC51_RS35300	COG0372	Belongs to the citrate synthase family
EJC51_RS35320	COG0523	cobalamin synthesis protein
EJC51_RS35325	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EJC51_RS35330	COG0612	Peptidase, M16
EJC51_RS35345	COG1802	Transcriptional regulator
EJC51_RS35350	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EJC51_RS35360	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EJC51_RS35360	COG1042	CoA-binding domain protein
EJC51_RS35360	COG0045	succinate-CoA ligase (ADP-forming) activity
EJC51_RS35375	COG1435	thymidine kinase activity
EJC51_RS35420	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EJC51_RS35430	COG0745	RESPONSE REGULATOR receiver
EJC51_RS35435	COG2205	protein histidine kinase activity
EJC51_RS35460	COG0756	dUTP diphosphatase activity
EJC51_RS35475	COG4591	ABC-type transport system involved in lipoprotein release permease component
EJC51_RS35475	COG1136	(ABC) transporter
EJC51_RS35505	COG0569	domain protein
EJC51_RS35510	COG0531	amino acid
EJC51_RS35515	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EJC51_RS35520	COG0402	S-adenosylhomocysteine deaminase activity
EJC51_RS35550	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EJC51_RS35555	COG0477	Major facilitator Superfamily
EJC51_RS35575	COG0277	FAD linked oxidase domain protein
EJC51_RS35575	COG0247	lactate metabolic process
EJC51_RS35595	COG0243	molybdopterin cofactor binding
EJC51_RS35600	COG1799	cell septum assembly
EJC51_RS35635	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EJC51_RS35650	COG2235	arginine
EJC51_RS35655	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EJC51_RS35660	COG0531	amino acid
EJC51_RS35670	COG1024	Enoyl-CoA hydratase
EJC51_RS35715	COG2409	Drug exporters of the RND superfamily
EJC51_RS35730	COG3938	Belongs to the proline racemase family
EJC51_RS35740	COG0446	pyridine nucleotide-disulphide oxidoreductase
EJC51_RS35750	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EJC51_RS35750	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EJC51_RS35755	COG0791	NLP P60 protein
EJC51_RS35760	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EJC51_RS35775	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EJC51_RS35780	COG2205	protein histidine kinase activity
EJC51_RS35805	COG3537	Alpha-1,2-mannosidase
EJC51_RS35810	COG3458	cephalosporin-C deacetylase activity
EJC51_RS35815	COG4209	transmembrane transport
EJC51_RS35820	COG0395	ABC-type sugar transport system, permease component
EJC51_RS35850	COG0714	Associated with various cellular activities
EJC51_RS35870	COG1653	transport
EJC51_RS35875	COG1175	transmembrane transport
EJC51_RS35880	COG0395	ABC-type sugar transport system, permease component
EJC51_RS35885	COG1940	carbohydrate kinase activity
EJC51_RS35890	COG4213	ABC transporter substrate-binding protein
EJC51_RS35900	COG4214	carbohydrate transport
EJC51_RS35905	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EJC51_RS35910	COG0531	amino acid
EJC51_RS35920	COG0596	Alpha beta hydrolase
EJC51_RS35945	COG1024	Enoyl-CoA hydratase
EJC51_RS35945	COG1250	3-hydroxyacyl-CoA dehydrogenase
EJC51_RS35950	COG0183	Belongs to the thiolase family
EJC51_RS35955	COG1609	Transcriptional regulator
EJC51_RS35960	COG3250	beta-galactosidase activity
EJC51_RS35970	COG1175	transmembrane transport
EJC51_RS35980	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EJC51_RS35995	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EJC51_RS36010	COG0446	pyridine nucleotide-disulphide oxidoreductase
EJC51_RS36025	COG3253	May function as heme-dependent peroxidase
EJC51_RS36045	COG3220	belongs to the UPF0276 family
EJC51_RS36075	COG1136	(ABC) transporter
EJC51_RS36075	COG0577	efflux transmembrane transporter activity
EJC51_RS36080	COG0577	efflux transmembrane transporter activity
EJC51_RS36080	COG1136	(ABC) transporter
EJC51_RS36105	COG2326	polyphosphate kinase activity
EJC51_RS36115	COG0330	HflC and HflK could
EJC51_RS36145	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EJC51_RS36150	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EJC51_RS36165	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EJC51_RS36175	COG1472	Belongs to the glycosyl hydrolase 3 family
EJC51_RS36190	COG1472	Belongs to the glycosyl hydrolase 3 family
EJC51_RS36195	COG0395	ABC-type sugar transport system, permease component
EJC51_RS36200	COG1175	transmembrane transport
EJC51_RS36220	COG1737	Transcriptional regulator
EJC51_RS36225	COG4821	SIS domain
EJC51_RS36230	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EJC51_RS36255	COG2205	protein histidine kinase activity
EJC51_RS36260	COG0745	RESPONSE REGULATOR receiver
EJC51_RS36275	COG1477	protein flavinylation
EJC51_RS36280	COG3206	protein involved in exopolysaccharide biosynthesis
EJC51_RS36280	COG0489	protein tyrosine kinase activity
EJC51_RS36295	COG1174	glycine betaine transport
EJC51_RS36300	COG1174	glycine betaine transport
EJC51_RS36305	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EJC51_RS36310	COG1595	DNA-templated transcription, initiation
EJC51_RS36325	COG2018	Roadblock/LC7 domain
EJC51_RS36330	COG5002	protein histidine kinase activity
EJC51_RS36340	COG2755	lipolytic protein G-D-S-L family
EJC51_RS36360	COG5002	protein histidine kinase activity
EJC51_RS36360	COG3850	Histidine kinase
EJC51_RS36375	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EJC51_RS36405	COG1404	Belongs to the peptidase S8 family
EJC51_RS36410	COG1309	transcriptional regulator
EJC51_RS36435	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EJC51_RS36440	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EJC51_RS36450	COG0504	CTP synthase activity
EJC51_RS36460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EJC51_RS36465	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EJC51_RS36545	COG1175	transmembrane transport
EJC51_RS36560	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EJC51_RS36580	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EJC51_RS36585	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EJC51_RS36605	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EJC51_RS36610	COG1116	anion transmembrane transporter activity
EJC51_RS36615	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EJC51_RS36635	COG0529	Catalyzes the synthesis of activated sulfate
EJC51_RS36640	COG0175	sulfate reduction
EJC51_RS36670	COG1960	acyl-CoA dehydrogenase activity
EJC51_RS36735	COG2040	homocysteine
EJC51_RS36760	COG2755	lipolytic protein G-D-S-L family
EJC51_RS36825	COG1131	(ABC) transporter
EJC51_RS36835	COG0395	ABC-type sugar transport system, permease component
EJC51_RS36840	COG1175	transmembrane transport
EJC51_RS36855	COG0277	FAD linked oxidase domain protein
EJC51_RS36875	COG5297	Belongs to the glycosyl hydrolase family 6
EJC51_RS36880	COG1162	GTPase activity
EJC51_RS36910	COG1404	Belongs to the peptidase S8 family
EJC51_RS36920	COG0028	Belongs to the TPP enzyme family
EJC51_RS36950	COG1802	Transcriptional regulator
EJC51_RS36965	COG3835	regulator
EJC51_RS36980	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EJC51_RS36985	COG2252	PERMEase
EJC51_RS37000	COG5634	Uncharacterized conserved protein (DUF2278)
EJC51_RS37005	COG0726	polysaccharide deacetylase
EJC51_RS37010	COG3940	Belongs to the glycosyl hydrolase 43 family
EJC51_RS37020	COG2226	methyltransferase
EJC51_RS37025	COG0596	Alpha beta hydrolase
EJC51_RS37035	COG1063	alcohol dehydrogenase
EJC51_RS37040	COG1028	Short-chain dehydrogenase reductase Sdr
EJC51_RS37070	COG3594	Acyltransferase
EJC51_RS37090	COG0598	Magnesium transport protein CorA
EJC51_RS37145	COG0477	Major facilitator Superfamily
EJC51_RS37155	COG0596	Alpha beta hydrolase
EJC51_RS37200	COG1028	Short-chain dehydrogenase reductase Sdr
EJC51_RS37210	COG1733	regulation of RNA biosynthetic process
EJC51_RS37220	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EJC51_RS37230	COG3852	Histidine kinase
EJC51_RS37240	COG2267	carboxylic ester hydrolase activity
EJC51_RS37245	COG1028	Short-chain dehydrogenase reductase Sdr
EJC51_RS37270	COG0598	Magnesium transport protein CorA
EJC51_RS37280	COG0583	DNA-binding transcription factor activity
EJC51_RS37300	COG2197	response regulator
EJC51_RS37305	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EJC51_RS37310	COG0318	PFAM AMP-dependent synthetase and ligase
EJC51_RS37325	COG3960	tartronate-semialdehyde synthase activity
EJC51_RS37335	COG0753	catalase activity
EJC51_RS37340	COG2084	Dehydrogenase
EJC51_RS37345	COG3622	Belongs to the hyi family
EJC51_RS37365	COG2351	hydroxyisourate hydrolase activity
EJC51_RS37380	COG2233	PERMEase
EJC51_RS37390	COG0702	epimerase
EJC51_RS37400	COG1733	regulation of RNA biosynthetic process
EJC51_RS37415	COG0406	alpha-ribazole phosphatase activity
EJC51_RS37440	COG4264	IucA IucC family
EJC51_RS37445	COG4264	IucA IucC family
EJC51_RS37460	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EJC51_RS37475	COG1414	Transcriptional regulator
EJC51_RS37480	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EJC51_RS37485	COG4266	Belongs to the allantoicase family
EJC51_RS37490	COG1028	Short-chain dehydrogenase reductase Sdr
EJC51_RS37540	COG2197	response regulator
EJC51_RS37550	COG0673	inositol 2-dehydrogenase activity
EJC51_RS37555	COG2188	Transcriptional regulator
EJC51_RS37560	COG1940	carbohydrate kinase activity
EJC51_RS37570	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EJC51_RS37585	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EJC51_RS37590	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EJC51_RS37610	COG1126	abc transporter atp-binding protein
EJC51_RS37625	COG0405	Gamma-glutamyltransferase
EJC51_RS37660	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EJC51_RS37675	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EJC51_RS37685	COG1953	Uracil, thiamine, allantoin
EJC51_RS37700	COG4585	Histidine kinase
EJC51_RS37705	COG2197	response regulator
EJC51_RS37710	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EJC51_RS37720	COG0483	inositol monophosphate 1-phosphatase activity
EJC51_RS37730	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EJC51_RS37755	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EJC51_RS37765	COG1404	Belongs to the peptidase S8 family
EJC51_RS37770	COG0494	nUDIX hydrolase
EJC51_RS37780	COG1929	Belongs to the glycerate kinase type-1 family
EJC51_RS37790	COG0410	ABC transporter
EJC51_RS37805	COG0559	Belongs to the binding-protein-dependent transport system permease family
EJC51_RS37820	COG0688	phosphatidylethanolamine metabolic process
EJC51_RS37840	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EJC51_RS37840	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EJC51_RS37855	COG1250	3-hydroxyacyl-CoA dehydrogenase
EJC51_RS37875	COG0596	Alpha beta hydrolase
EJC51_RS37900	COG2226	methyltransferase
EJC51_RS37905	COG2362	D-Aminopeptidase
EJC51_RS37910	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EJC51_RS37920	COG1619	proteins homologs of microcin C7 resistance protein MccF
EJC51_RS37945	COG0457	Tetratricopeptide repeat
EJC51_RS37965	COG1028	Short-chain dehydrogenase reductase Sdr
EJC51_RS37970	COG4948	Mandelate Racemase Muconate Lactonizing
EJC51_RS37975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EJC51_RS37980	COG1252	NADH dehydrogenase
EJC51_RS37990	COG1793	dna ligase
EJC51_RS37990	COG3285	dna ligase
EJC51_RS38050	COG2226	methyltransferase
EJC51_RS38055	COG1597	lipid kinase activity
EJC51_RS38065	COG0488	(ABC) transporter
EJC51_RS38085	COG0693	protein deglycase activity
EJC51_RS38095	COG0517	IMP dehydrogenase activity
EJC51_RS38095	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EJC51_RS38110	COG0028	Belongs to the TPP enzyme family
EJC51_RS38165	COG0443	Heat shock 70 kDa protein
EJC51_RS38175	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EJC51_RS38180	COG1140	nitrate reductase beta subunit
EJC51_RS38210	COG2154	pterin-4-alpha-carbinolamine dehydratase
EJC51_RS38230	COG2378	regulation of single-species biofilm formation
EJC51_RS38235	COG3401	FG-GAP repeat protein
EJC51_RS38245	COG5297	Belongs to the glycosyl hydrolase family 6
EJC51_RS38245	COG4733	cellulase activity
EJC51_RS38250	COG5297	Belongs to the glycosyl hydrolase family 6
EJC51_RS38275	COG2197	response regulator
EJC51_RS38280	COG0656	L-ascorbic acid biosynthetic process
EJC51_RS38325	COG1335	isochorismatase
EJC51_RS38330	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EJC51_RS38340	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EJC51_RS38350	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EJC51_RS38365	COG1940	carbohydrate kinase activity
EJC51_RS38370	COG1129	ABC transporter
EJC51_RS38375	COG1172	Belongs to the binding-protein-dependent transport system permease family
EJC51_RS38385	COG0673	inositol 2-dehydrogenase activity
EJC51_RS38455	COG2223	nitrite transmembrane transporter activity
EJC51_RS38460	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EJC51_RS38465	COG0045	succinate-CoA ligase (ADP-forming) activity
EJC51_RS38475	COG1012	belongs to the aldehyde dehydrogenase family
EJC51_RS38480	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EJC51_RS38495	COG1802	Transcriptional regulator
EJC51_RS38510	COG3383	formate dehydrogenase (NAD+) activity
EJC51_RS38520	COG0583	DNA-binding transcription factor activity
EJC51_RS38525	COG0318	PFAM AMP-dependent synthetase and ligase
EJC51_RS38530	COG0028	Belongs to the TPP enzyme family
EJC51_RS38535	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EJC51_RS38555	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EJC51_RS38565	COG2182	Extracellular solute-binding protein
EJC51_RS38570	COG1175	transmembrane transport
EJC51_RS38575	COG0395	ABC-type sugar transport system, permease component
EJC51_RS38580	COG2723	6-phospho-beta-galactosidase activity
EJC51_RS38585	COG2223	nitrite transmembrane transporter activity
EJC51_RS38615	COG0747	negative chemotaxis
EJC51_RS38630	COG1183	phosphatidylcholine synthase activity
EJC51_RS38645	COG0297	glycogen (starch) synthase activity
EJC51_RS38665	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EJC51_RS38690	COG0477	Major facilitator Superfamily
EJC51_RS38700	COG3467	pyridoxamine 5'-phosphate
EJC51_RS38705	COG0346	lactoylglutathione lyase activity
EJC51_RS38710	COG0477	Major facilitator Superfamily
EJC51_RS38720	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EJC51_RS38725	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EJC51_RS38725	COG1082	Xylose isomerase domain protein TIM barrel
EJC51_RS38750	COG0588	phosphoglycerate mutase activity
EJC51_RS38755	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EJC51_RS38760	COG0166	Belongs to the GPI family
EJC51_RS38775	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EJC51_RS38800	COG2409	Drug exporters of the RND superfamily
EJC51_RS38810	COG2197	response regulator
EJC51_RS38815	COG4585	Histidine kinase
EJC51_RS38830	COG1028	Short-chain dehydrogenase reductase Sdr
EJC51_RS38850	COG0641	radical SAM
EJC51_RS38865	COG3903	Transcriptional regulator
EJC51_RS38865	COG3629	intracellular signal transduction
EJC51_RS38870	COG2267	carboxylic ester hydrolase activity
EJC51_RS38890	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EJC51_RS38895	COG3250	beta-galactosidase activity
EJC51_RS38900	COG0395	ABC-type sugar transport system, permease component
EJC51_RS38905	COG1175	transmembrane transport
EJC51_RS38915	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EJC51_RS38925	COG1486	melibiose metabolic process
EJC51_RS38940	COG3469	chitinase activity
EJC51_RS38950	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EJC51_RS38995	COG3842	ATPase activity
EJC51_RS39000	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EJC51_RS39005	COG1176	ABC-type spermidine putrescine transport system, permease component I
EJC51_RS39010	COG1177	transmembrane transport
EJC51_RS39025	COG1175	transmembrane transport
EJC51_RS39030	COG0395	ABC-type sugar transport system, permease component
EJC51_RS39035	COG0366	Alpha amylase catalytic
EJC51_RS39045	COG1116	anion transmembrane transporter activity
EJC51_RS39050	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EJC51_RS39055	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EJC51_RS39060	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EJC51_RS39080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EJC51_RS39090	COG3511	phospholipase C
EJC51_RS39125	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EJC51_RS39130	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EJC51_RS39135	COG3485	protocatechuate 3,4-dioxygenase
EJC51_RS39140	COG3485	protocatechuate 3,4-dioxygenase
EJC51_RS39160	COG1793	dna ligase
EJC51_RS39255	COG1834	amidinotransferase
EJC51_RS39260	COG0488	(ABC) transporter
EJC51_RS39305	COG3268	Saccharopine dehydrogenase
EJC51_RS39310	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EJC51_RS39315	COG1960	acyl-CoA dehydrogenase activity
EJC51_RS39320	COG0183	Belongs to the thiolase family
EJC51_RS39325	COG1024	Enoyl-CoA hydratase
EJC51_RS39325	COG1250	3-hydroxyacyl-CoA dehydrogenase
EJC51_RS39330	COG0789	Transcriptional regulator
EJC51_RS39335	COG1113	amino acid transport
EJC51_RS39345	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EJC51_RS39350	COG0010	Belongs to the arginase family
EJC51_RS39360	COG2936	dipeptidyl-peptidase activity
EJC51_RS39365	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EJC51_RS39380	COG0488	(ABC) transporter
EJC51_RS39385	COG2183	response to ionizing radiation
EJC51_RS39405	COG1024	Enoyl-CoA hydratase
EJC51_RS39420	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EJC51_RS39465	COG1134	teichoic acid transport
EJC51_RS39470	COG1562	ergosterol biosynthetic process
EJC51_RS39480	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EJC51_RS39490	COG1657	PFAM Prenyltransferase squalene oxidase
EJC51_RS39505	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EJC51_RS39510	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EJC51_RS39530	COG2365	Tyrosine phosphatase family
EJC51_RS39560	COG2755	lipolytic protein G-D-S-L family
EJC51_RS39565	COG2968	Membrane
EJC51_RS39635	COG1063	alcohol dehydrogenase
EJC51_RS39640	COG0156	8-amino-7-oxononanoate synthase activity
EJC51_RS39645	COG0583	DNA-binding transcription factor activity
EJC51_RS39675	COG1090	epimerase
EJC51_RS39680	COG0673	inositol 2-dehydrogenase activity
EJC51_RS39685	COG1609	Transcriptional regulator
EJC51_RS39700	COG0583	DNA-binding transcription factor activity
EJC51_RS39705	COG5006	permease, DMT superfamily
EJC51_RS39715	COG3387	PFAM Glycoside hydrolase 15-related
EJC51_RS39720	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EJC51_RS39735	COG0174	glutamine synthetase
EJC51_RS39750	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EJC51_RS39755	COG1396	sequence-specific DNA binding
EJC51_RS39760	COG0006	proline dipeptidase activity
EJC51_RS39765	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EJC51_RS39770	COG0022	dehydrogenase e1 component
EJC51_RS39775	COG0402	S-adenosylhomocysteine deaminase activity
EJC51_RS39815	COG2267	carboxylic ester hydrolase activity
EJC51_RS39820	COG0183	Belongs to the thiolase family
EJC51_RS39875	COG0438	transferase activity, transferring glycosyl groups
EJC51_RS39925	COG1088	dTDP-glucose 4,6-dehydratase activity
EJC51_RS39940	COG1316	TRANSCRIPTIONal
EJC51_RS39945	COG3387	PFAM Glycoside hydrolase 15-related
EJC51_RS39950	COG0513	Belongs to the DEAD box helicase family
EJC51_RS39955	COG1278	Cold shock
EJC51_RS39960	COG0494	nUDIX hydrolase
EJC51_RS39970	COG2188	Transcriptional regulator
EJC51_RS39975	COG3962	Belongs to the TPP enzyme family
EJC51_RS39980	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EJC51_RS40005	COG0673	inositol 2-dehydrogenase activity
EJC51_RS40015	COG0673	inositol 2-dehydrogenase activity
EJC51_RS40020	COG0673	inositol 2-dehydrogenase activity
EJC51_RS40025	COG1028	Short-chain dehydrogenase reductase Sdr
EJC51_RS40035	COG1609	Transcriptional regulator
EJC51_RS40050	COG3485	protocatechuate 3,4-dioxygenase
EJC51_RS40055	COG1454	alcohol dehydrogenase
EJC51_RS40070	COG2186	Transcriptional regulator
EJC51_RS40075	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EJC51_RS40080	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EJC51_RS40100	COG0477	Major facilitator Superfamily
EJC51_RS40130	COG0765	amino acid transport
EJC51_RS40135	COG1126	abc transporter atp-binding protein
EJC51_RS40140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EJC51_RS40145	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EJC51_RS40150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EJC51_RS40155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EJC51_RS40160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EJC51_RS40175	COG2197	response regulator
EJC51_RS40200	COG2124	cytochrome p450
EJC51_RS40225	COG2838	Isocitrate dehydrogenase
EJC51_RS40235	COG0668	transmembrane transport
EJC51_RS40240	COG0531	amino acid
EJC51_RS40250	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EJC51_RS40255	COG2022	thiamine diphosphate biosynthetic process
EJC51_RS40255	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EJC51_RS40265	COG1024	Enoyl-CoA hydratase
EJC51_RS40280	COG1132	(ABC) transporter
EJC51_RS40300	COG3618	amidohydrolase
EJC51_RS40315	COG0395	ABC-type sugar transport system, permease component
EJC51_RS40320	COG1175	transmembrane transport
EJC51_RS40330	COG2186	Transcriptional regulator
EJC51_RS40335	COG1703	isobutyryl-CoA mutase activity
EJC51_RS40335	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EJC51_RS40335	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EJC51_RS40340	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EJC51_RS40355	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EJC51_RS40360	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
EJC51_RS40385	COG0297	glycogen (starch) synthase activity
EJC51_RS40390	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EJC51_RS40410	COG1028	Short-chain dehydrogenase reductase Sdr
EJC51_RS40425	COG0154	amidase activity
EJC51_RS40440	COG1609	Transcriptional regulator
EJC51_RS40450	COG1175	transmembrane transport
EJC51_RS40455	COG0395	ABC-type sugar transport system, permease component
EJC51_RS40485	COG2186	Transcriptional regulator
EJC51_RS40490	COG1879	ABC-type sugar transport system periplasmic component
EJC51_RS40495	COG1129	ABC transporter
EJC51_RS40505	COG4948	Mandelate Racemase Muconate Lactonizing
EJC51_RS40510	COG1028	Short-chain dehydrogenase reductase Sdr
EJC51_RS40535	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EJC51_RS40570	COG2267	carboxylic ester hydrolase activity
EJC51_RS40580	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EJC51_RS40580	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EJC51_RS40585	COG0726	polysaccharide deacetylase
EJC51_RS40635	COG0583	DNA-binding transcription factor activity
EJC51_RS40645	COG1053	succinate dehydrogenase
EJC51_RS40650	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EJC51_RS40680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EJC51_RS40685	COG0523	cobalamin synthesis protein
EJC51_RS40700	COG3360	Dodecin
EJC51_RS40705	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
EJC51_RS40710	COG0121	glutamine amidotransferase
EJC51_RS40715	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EJC51_RS40735	COG2268	Band 7 protein
EJC51_RS40760	COG2226	methyltransferase
EJC51_RS40805	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EJC51_RS40815	COG0656	L-ascorbic acid biosynthetic process
EJC51_RS40855	COG0583	DNA-binding transcription factor activity
EJC51_RS40870	COG1609	Transcriptional regulator
EJC51_RS40880	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EJC51_RS40890	COG0242	peptide deformylase activity
EJC51_RS40940	COG0542	response to heat
EJC51_RS40950	COG1136	(ABC) transporter
EJC51_RS40955	COG1174	glycine betaine transport
EJC51_RS40960	COG1174	glycine betaine transport
EJC51_RS40985	COG1819	glycosyl
EJC51_RS40995	COG3250	beta-galactosidase activity
EJC51_RS41000	COG1556	Lactate utilization protein
EJC51_RS41005	COG1139	Iron-sulfur cluster binding protein
EJC51_RS41010	COG0247	lactate metabolic process
EJC51_RS41015	COG1070	Carbohydrate kinase
EJC51_RS41020	COG1028	Short-chain dehydrogenase reductase Sdr
EJC51_RS41020	COG3347	Dehydrogenase
EJC51_RS41030	COG1129	ABC transporter
EJC51_RS41035	COG1172	Belongs to the binding-protein-dependent transport system permease family
EJC51_RS41045	COG1879	ABC-type sugar transport system periplasmic component
EJC51_RS41060	COG1609	Transcriptional regulator
EJC51_RS41075	COG1595	DNA-templated transcription, initiation
EJC51_RS41085	COG1357	PFAM Pentapeptide repeats (8 copies)
EJC51_RS41095	COG1309	transcriptional regulator
EJC51_RS41105	COG2706	6-phosphogluconolactonase activity
EJC51_RS41125	COG0604	alcohol dehydrogenase
EJC51_RS41125	COG1028	Short-chain dehydrogenase reductase Sdr
EJC51_RS41125	COG3321	synthase
EJC51_RS41175	COG1796	DNA polymerase
EJC51_RS41175	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EJC51_RS41220	COG1006	Multisubunit Na H antiporter MnhC subunit
EJC51_RS41225	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EJC51_RS41245	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EJC51_RS41265	COG1012	belongs to the aldehyde dehydrogenase family
EJC51_RS41340	COG0531	amino acid
EJC51_RS41360	COG0435	Glutathione S-transferase
EJC51_RS41390	COG2124	cytochrome p450
EJC51_RS41415	COG0667	Aldo Keto reductase
EJC51_RS41450	COG1595	DNA-templated transcription, initiation
EJC51_RS41465	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EJC51_RS41485	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EJC51_RS41505	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EJC51_RS41535	COG0248	Ppx GppA phosphatase
EJC51_RS41545	COG0596	Alpha beta hydrolase
EJC51_RS41595	COG2197	response regulator
EJC51_RS41605	COG1132	(ABC) transporter
EJC51_RS41615	COG0515	serine threonine protein kinase
EJC51_RS41635	COG3510	cephalosporin hydroxylase
EJC51_RS41655	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EJC51_RS41685	COG3345	alpha-galactosidase
EJC51_RS41695	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EJC51_RS41710	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EJC51_RS41730	COG1012	belongs to the aldehyde dehydrogenase family
EJC51_RS41735	COG0019	diaminopimelate decarboxylase activity
EJC51_RS41745	COG2814	Major facilitator Superfamily
EJC51_RS41755	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EJC51_RS41760	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EJC51_RS41765	COG1120	ATPase activity
EJC51_RS41770	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EJC51_RS41775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EJC51_RS41800	COG3958	Transketolase
EJC51_RS41825	COG1028	Short-chain dehydrogenase reductase Sdr
EJC51_RS41840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EJC51_RS41860	COG0395	ABC-type sugar transport system, permease component
EJC51_RS41865	COG1175	transmembrane transport
EJC51_RS41870	COG1940	carbohydrate kinase activity
EJC51_RS41870	COG1846	Transcriptional regulator
EJC51_RS41910	COG1609	Transcriptional regulator
EJC51_RS41930	COG0395	ABC-type sugar transport system, permease component
EJC51_RS41935	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EJC51_RS41950	COG5492	domain, Protein
EJC51_RS41995	COG1940	carbohydrate kinase activity
EJC51_RS42010	COG0395	ABC-type sugar transport system, permease component
EJC51_RS42025	COG0702	epimerase
EJC51_RS42030	COG1733	regulation of RNA biosynthetic process
EJC51_RS42055	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
EJC51_RS42060	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
EJC51_RS42090	COG2409	Drug exporters of the RND superfamily
EJC51_RS42120	COG0673	inositol 2-dehydrogenase activity
EJC51_RS42125	COG0667	Aldo Keto reductase
EJC51_RS42130	COG1132	(ABC) transporter
EJC51_RS42195	COG0640	Transcriptional regulator
EJC51_RS42200	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EJC51_RS42225	COG0456	acetyltransferase
EJC51_RS42230	COG3321	synthase
EJC51_RS42230	COG1028	Short-chain dehydrogenase reductase Sdr
EJC51_RS42230	COG0604	alcohol dehydrogenase
EJC51_RS42255	COG3290	protein histidine kinase activity
EJC51_RS42285	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EJC51_RS42295	COG0697	spore germination
EJC51_RS42300	COG1846	Transcriptional regulator
EJC51_RS42330	COG2197	response regulator
EJC51_RS42350	COG2814	Major facilitator Superfamily
EJC51_RS42375	COG0129	dihydroxy-acid dehydratase activity
EJC51_RS42380	COG1414	Transcriptional regulator
EJC51_RS42385	COG0179	Fumarylacetoacetate (FAA) hydrolase
EJC51_RS42390	COG1063	alcohol dehydrogenase
EJC51_RS42400	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EJC51_RS42410	COG0702	epimerase
EJC51_RS42445	COG0596	Alpha beta hydrolase
EJC51_RS42460	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EJC51_RS42470	COG1595	DNA-templated transcription, initiation
EJC51_RS42490	COG4585	Histidine kinase
EJC51_RS42495	COG2197	response regulator
EJC51_RS42520	COG1765	OsmC-like protein
EJC51_RS42535	COG0395	ABC-type sugar transport system, permease component
EJC51_RS42550	COG1609	Transcriptional regulator
EJC51_RS42560	COG2132	Multicopper oxidase
EJC51_RS42575	COG0583	DNA-binding transcription factor activity
EJC51_RS42580	COG0281	malic enzyme
EJC51_RS42585	COG3619	membrane
EJC51_RS42625	COG0714	Associated with various cellular activities
EJC51_RS42665	COG1522	sequence-specific DNA binding
EJC51_RS42680	COG2378	regulation of single-species biofilm formation
EJC51_RS42705	COG0583	DNA-binding transcription factor activity
EJC51_RS42725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EJC51_RS42730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EJC51_RS42745	COG2814	Major facilitator Superfamily
EJC51_RS42775	COG4585	Histidine kinase
EJC51_RS42780	COG2197	response regulator
EJC51_RS42785	COG1295	ribonuclease BN
EJC51_RS42805	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
EJC51_RS42815	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EJC51_RS42820	COG0596	Alpha beta hydrolase
EJC51_RS42825	COG1609	Transcriptional regulator
EJC51_RS42835	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EJC51_RS42845	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EJC51_RS42870	COG0577	efflux transmembrane transporter activity
EJC51_RS42880	COG2197	response regulator
EJC51_RS42905	COG2197	response regulator
EJC51_RS42920	COG4552	Acetyltransferase involved in intracellular survival and related
EJC51_RS42930	COG1132	(ABC) transporter
EJC51_RS42940	COG1733	regulation of RNA biosynthetic process
EJC51_RS42975	COG1278	Cold shock
EJC51_RS43000	COG1940	carbohydrate kinase activity
EJC51_RS43005	COG1129	ABC transporter
EJC51_RS43010	COG1172	Belongs to the binding-protein-dependent transport system permease family
EJC51_RS43020	COG0673	inositol 2-dehydrogenase activity
EJC51_RS43040	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EJC51_RS43065	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EJC51_RS43080	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EJC51_RS43105	COG0583	DNA-binding transcription factor activity
EJC51_RS43110	COG0183	Belongs to the thiolase family
EJC51_RS43120	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EJC51_RS43125	COG2197	response regulator
EJC51_RS43130	COG4585	Histidine kinase
EJC51_RS43135	COG2409	Drug exporters of the RND superfamily
EJC51_RS43140	COG1970	mechanosensitive ion channel activity
EJC51_RS43150	COG1408	metallophosphoesterase
EJC51_RS43170	COG2814	Major facilitator Superfamily
EJC51_RS43180	COG0174	glutamine synthetase
EJC51_RS43195	COG4689	acetoacetate decarboxylase
EJC51_RS43235	COG1012	belongs to the aldehyde dehydrogenase family
EJC51_RS43240	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EJC51_RS43245	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EJC51_RS43255	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EJC51_RS43265	COG1846	Transcriptional regulator
EJC51_RS43285	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EJC51_RS43295	COG0701	Predicted permease
EJC51_RS43330	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EJC51_RS43330	COG2755	lipolytic protein G-D-S-L family
EJC51_RS43340	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EJC51_RS43345	COG1733	regulation of RNA biosynthetic process
EJC51_RS43350	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EJC51_RS43390	COG1414	Transcriptional regulator
EJC51_RS43425	COG2197	response regulator
EJC51_RS43440	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EJC51_RS43445	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EJC51_RS43460	COG2409	Drug exporters of the RND superfamily
EJC51_RS43470	COG3321	synthase
EJC51_RS43470	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EJC51_RS43480	COG1960	acyl-CoA dehydrogenase activity
EJC51_RS43525	COG1595	DNA-templated transcription, initiation
EJC51_RS43535	COG3409	Peptidoglycan-binding domain 1 protein
EJC51_RS43560	COG0095	Lipoate-protein ligase
EJC51_RS43565	COG2319	Wd-40 repeat
EJC51_RS43565	COG4249	Peptidase C14 caspase catalytic subunit p20
EJC51_RS43590	COG0326	Molecular chaperone. Has ATPase activity
EJC51_RS43595	COG0384	phenazine biosynthesis protein PhzF
EJC51_RS43620	COG0596	Alpha beta hydrolase
EJC51_RS43630	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EJC51_RS43675	COG0583	DNA-binding transcription factor activity
EJC51_RS43720	COG0640	Transcriptional regulator
EJC51_RS43730	COG1247	-acetyltransferase
EJC51_RS43735	COG0583	DNA-binding transcription factor activity
EJC51_RS43740	COG4221	oxidoreductase activity
EJC51_RS43780	COG2084	Dehydrogenase
EJC51_RS43815	COG0395	ABC-type sugar transport system, permease component
EJC51_RS43820	COG1175	transmembrane transport
EJC51_RS43835	COG1028	Short-chain dehydrogenase reductase Sdr
EJC51_RS43840	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EJC51_RS43845	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EJC51_RS43850	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EJC51_RS43870	COG0667	Aldo Keto reductase
EJC51_RS43895	COG2814	Major facilitator Superfamily
EJC51_RS43920	COG3290	protein histidine kinase activity
EJC51_RS43925	COG4565	transcriptional regulatory protein
EJC51_RS43945	COG4221	oxidoreductase activity
EJC51_RS43950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EJC51_RS43960	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EJC51_RS43970	COG0747	negative chemotaxis
EJC51_RS43975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EJC51_RS44060	COG1028	Short-chain dehydrogenase reductase Sdr
EJC51_RS44065	COG2267	carboxylic ester hydrolase activity
EJC51_RS44090	COG0395	ABC-type sugar transport system, permease component
EJC51_RS44095	COG1175	transmembrane transport
EJC51_RS44100	COG2182	Extracellular solute-binding protein
EJC51_RS44110	COG1609	Transcriptional regulator
EJC51_RS44135	COG2226	methyltransferase
EJC51_RS44145	COG1028	Short-chain dehydrogenase reductase Sdr
EJC51_RS44165	COG1454	alcohol dehydrogenase
EJC51_RS44170	COG3485	protocatechuate 3,4-dioxygenase
EJC51_RS44195	COG3507	Belongs to the glycosyl hydrolase 43 family
EJC51_RS44205	COG2186	Transcriptional regulator
EJC51_RS44225	COG0300	oxidoreductase activity
EJC51_RS44240	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EJC51_RS44280	COG2755	lipolytic protein G-D-S-L family
EJC51_RS44300	COG2223	nitrite transmembrane transporter activity
EJC51_RS44305	COG2072	flavoprotein involved in K transport
EJC51_RS44315	COG1012	belongs to the aldehyde dehydrogenase family
EJC51_RS44335	COG0667	Aldo Keto reductase
EJC51_RS44360	COG5297	Belongs to the glycosyl hydrolase family 6
EJC51_RS44365	COG4733	cellulase activity
EJC51_RS44365	COG5297	Belongs to the glycosyl hydrolase family 6
EJC51_RS44430	COG0542	response to heat
EJC51_RS44445	COG2837	iron assimilation
EJC51_RS44475	COG1309	transcriptional regulator
EJC51_RS44480	COG0596	Alpha beta hydrolase
EJC51_RS44505	COG1191	sigma factor activity
EJC51_RS44520	COG1366	Belongs to the anti-sigma-factor antagonist family
EJC51_RS44525	COG1366	Belongs to the anti-sigma-factor antagonist family
EJC51_RS44530	COG2172	sigma factor antagonist activity
EJC51_RS44560	COG1366	Belongs to the anti-sigma-factor antagonist family
EJC51_RS44565	COG5002	protein histidine kinase activity
EJC51_RS44565	COG2205	protein histidine kinase activity
EJC51_RS44565	COG0784	Response regulator, receiver
EJC51_RS44610	COG1309	transcriptional regulator
EJC51_RS44625	COG1309	transcriptional regulator
EJC51_RS44650	COG1309	transcriptional regulator
EJC51_RS44680	COG1733	regulation of RNA biosynthetic process
EJC51_RS44685	COG0596	Alpha beta hydrolase
EJC51_RS44690	COG2130	NADP-dependent
EJC51_RS44695	COG0789	Transcriptional regulator
EJC51_RS44720	COG4221	oxidoreductase activity
EJC51_RS44725	COG2409	Drug exporters of the RND superfamily
EJC51_RS44735	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EJC51_RS44740	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EJC51_RS44745	COG0179	Fumarylacetoacetate (FAA) hydrolase
EJC51_RS44770	COG0477	Major facilitator Superfamily
EJC51_RS44780	COG0515	serine threonine protein kinase
EJC51_RS44820	COG2770	Histidine kinase
EJC51_RS44820	COG2208	phosphoserine phosphatase activity
EJC51_RS44880	COG3345	alpha-galactosidase
EJC51_RS44925	COG2755	lipolytic protein G-D-S-L family
EJC51_RS44945	COG0789	Transcriptional regulator
EJC51_RS44950	COG1028	Short-chain dehydrogenase reductase Sdr
EJC51_RS44955	COG2197	response regulator
EJC51_RS44960	COG4585	Histidine kinase
EJC51_RS44965	COG2409	Drug exporters of the RND superfamily
EJC51_RS44970	COG2409	Drug exporters of the RND superfamily
EJC51_RS44975	COG2205	protein histidine kinase activity
EJC51_RS44980	COG0745	RESPONSE REGULATOR receiver
EJC51_RS44990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EJC51_RS44995	COG1120	ATPase activity
EJC51_RS45005	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EJC51_RS45035	COG1953	Uracil, thiamine, allantoin
EJC51_RS45045	COG0583	DNA-binding transcription factor activity
EJC51_RS45050	COG1028	Short-chain dehydrogenase reductase Sdr
EJC51_RS45110	COG0583	DNA-binding transcription factor activity
EJC51_RS45125	COG2226	methyltransferase
EJC51_RS45160	COG2124	cytochrome p450
EJC51_RS45185	COG2197	response regulator
EJC51_RS45195	COG3340	Belongs to the peptidase S51 family
EJC51_RS45205	COG3251	PFAM MbtH domain protein
EJC51_RS45220	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EJC51_RS45225	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EJC51_RS45235	COG4608	Belongs to the ABC transporter superfamily
EJC51_RS45250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EJC51_RS45260	COG2267	carboxylic ester hydrolase activity
EJC51_RS45265	COG2186	Transcriptional regulator
EJC51_RS45275	COG2315	Protein conserved in bacteria
EJC51_RS45295	COG2272	Belongs to the type-B carboxylesterase lipase family
EJC51_RS45305	COG0702	epimerase
EJC51_RS45335	COG3903	Transcriptional regulator
EJC51_RS45335	COG3629	intracellular signal transduction
EJC51_RS45355	COG1012	belongs to the aldehyde dehydrogenase family
EJC51_RS45460	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EJC51_RS45515	COG3629	intracellular signal transduction
EJC51_RS45515	COG3903	Transcriptional regulator
EJC51_RS45520	COG0010	Belongs to the arginase family
EJC51_RS45625	COG2732	(Barnase) inhibitor
EJC51_RS45705	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EJC51_RS45745	COG1175	transmembrane transport
EJC51_RS45750	COG0395	ABC-type sugar transport system, permease component
EJC51_RS45755	COG0300	oxidoreductase activity
EJC51_RS45760	COG0300	oxidoreductase activity
EJC51_RS45775	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EJC51_RS45795	COG2814	Major facilitator Superfamily
EJC51_RS45800	COG1309	transcriptional regulator
EJC51_RS45810	COG0477	Major facilitator Superfamily
EJC51_RS45830	COG2030	dehydratase
EJC51_RS45845	COG1028	Short-chain dehydrogenase reductase Sdr
EJC51_RS45875	COG0561	phosphatase activity
EJC51_RS45895	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EJC51_RS45900	COG1028	Short-chain dehydrogenase reductase Sdr
EJC51_RS45910	COG1309	transcriptional regulator
EJC51_RS45945	COG1028	Short-chain dehydrogenase reductase Sdr
EJC51_RS45965	COG3485	protocatechuate 3,4-dioxygenase
EJC51_RS45970	COG1454	alcohol dehydrogenase
EJC51_RS46005	COG1309	transcriptional regulator
EJC51_RS46015	COG0583	DNA-binding transcription factor activity
EJC51_RS46020	COG0183	Belongs to the thiolase family
EJC51_RS46030	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EJC51_RS46040	COG1431	PFAM Stem cell self-renewal protein Piwi
EJC51_RS46260	COG2319	Wd-40 repeat
EJC51_RS46260	COG4249	Peptidase C14 caspase catalytic subunit p20
EJC51_RS46295	COG1609	Transcriptional regulator
EJC51_RS46300	COG1653	transport
EJC51_RS46315	COG0366	Alpha amylase catalytic
EJC51_RS46345	COG5000	phosphorelay sensor kinase activity
EJC51_RS46345	COG5002	protein histidine kinase activity
EJC51_RS46420	COG0667	Aldo Keto reductase
EJC51_RS46525	COG0745	RESPONSE REGULATOR receiver
EJC51_RS46530	COG2205	protein histidine kinase activity
EJC51_RS46555	COG4585	Histidine kinase
EJC51_RS46560	COG2197	response regulator
EJC51_RS46595	COG1136	(ABC) transporter
EJC51_RS46600	COG1136	(ABC) transporter
EJC51_RS46610	COG5002	protein histidine kinase activity
EJC51_RS46625	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EJC51_RS46635	COG3290	protein histidine kinase activity
EJC51_RS46640	COG4565	transcriptional regulatory protein
EJC51_RS46650	COG2205	protein histidine kinase activity
EJC51_RS46655	COG0745	RESPONSE REGULATOR receiver
EJC51_RS46660	COG0671	phosphoesterase, PA-phosphatase related
EJC51_RS46665	COG0671	phosphoesterase, PA-phosphatase related
EJC51_RS46685	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EJC51_RS46690	COG0019	diaminopimelate decarboxylase activity
EJC51_RS46710	COG0601	transmembrane transport
EJC51_RS46715	COG4171	peptide transport system, permease
EJC51_RS46720	COG4172	Belongs to the ABC transporter superfamily
EJC51_RS46725	COG0726	polysaccharide deacetylase
EJC51_RS46730	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EJC51_RS46750	COG1621	beta-fructofuranosidase activity
EJC51_RS46775	COG0297	glycogen (starch) synthase activity
EJC51_RS46780	COG0717	Belongs to the dCTP deaminase family
EJC51_RS46785	COG0717	Belongs to the dCTP deaminase family
EJC51_RS46795	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EJC51_RS46875	COG0477	Major facilitator Superfamily
EJC51_RS46910	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EJC51_RS46920	COG1414	Transcriptional regulator
EJC51_RS46930	COG3971	2-oxopent-4-enoate hydratase activity
EJC51_RS46935	COG4569	acetaldehyde dehydrogenase (acetylating) activity
EJC51_RS46940	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EJC51_RS46955	COG0842	Transport permease protein
EJC51_RS46955	COG1129	ABC transporter
EJC51_RS46960	COG0142	geranyltranstransferase activity
EJC51_RS46965	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EJC51_RS47005	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EJC51_RS47105	COG1011	Hydrolase
EJC51_RS47220	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EJC51_RS47300	COG1793	dna ligase
EJC51_RS47300	COG3285	dna ligase
EJC51_RS47330	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EJC51_RS47340	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase