locus-tag	class	description
KQY30_RS00140	COG0277	FAD linked oxidase domain protein
KQY30_RS00150	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KQY30_RS00155	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KQY30_RS00170	COG0179	Fumarylacetoacetate (FAA) hydrolase
KQY30_RS00175	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KQY30_RS00180	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KQY30_RS00185	COG1028	Short-chain dehydrogenase reductase Sdr
KQY30_RS00190	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KQY30_RS00195	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
KQY30_RS00235	COG0596	Alpha beta hydrolase
KQY30_RS00240	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
KQY30_RS00245	COG1181	Belongs to the D-alanine--D-alanine ligase family
KQY30_RS00255	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KQY30_RS00275	COG2205	protein histidine kinase activity
KQY30_RS00305	COG2226	methyltransferase
KQY30_RS00335	COG4977	sequence-specific DNA binding
KQY30_RS00375	COG2409	Drug exporters of the RND superfamily
KQY30_RS00380	COG0745	RESPONSE REGULATOR receiver
KQY30_RS00385	COG5002	protein histidine kinase activity
KQY30_RS00390	COG1609	Transcriptional regulator
KQY30_RS00405	COG0395	ABC-type sugar transport system, permease component
KQY30_RS00455	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KQY30_RS00505	COG2159	amidohydrolase
KQY30_RS00510	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KQY30_RS00525	COG0698	ribose 5-phosphate isomerase
KQY30_RS00535	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KQY30_RS00555	COG0588	phosphoglycerate mutase activity
KQY30_RS00580	COG1177	transmembrane transport
KQY30_RS00585	COG3842	ATPase activity
KQY30_RS00600	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KQY30_RS00650	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
KQY30_RS00690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KQY30_RS00695	COG1309	transcriptional regulator
KQY30_RS00705	COG0183	Belongs to the thiolase family
KQY30_RS00710	COG3396	Phenylacetate-CoA oxygenase
KQY30_RS00715	COG3460	Phenylacetate-CoA oxygenase
KQY30_RS00720	COG3396	Phenylacetate-CoA oxygenase
KQY30_RS00725	COG2151	metal-sulfur cluster biosynthetic enzyme
KQY30_RS00730	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KQY30_RS00750	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KQY30_RS00780	COG3345	alpha-galactosidase
KQY30_RS00785	COG0395	ABC-type sugar transport system, permease component
KQY30_RS00790	COG1175	transmembrane transport
KQY30_RS00800	COG1940	carbohydrate kinase activity
KQY30_RS00800	COG1846	Transcriptional regulator
KQY30_RS00845	COG1473	amidohydrolase
KQY30_RS00870	COG1994	Peptidase M50
KQY30_RS00905	COG1349	DNA-binding transcription factor activity
KQY30_RS00910	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KQY30_RS00925	COG0601	transmembrane transport
KQY30_RS00930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KQY30_RS00935	COG0444	Belongs to the ABC transporter superfamily
KQY30_RS00940	COG4608	Belongs to the ABC transporter superfamily
KQY30_RS00945	COG0667	Aldo Keto reductase
KQY30_RS00970	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KQY30_RS00975	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KQY30_RS01020	COG5650	phosphatidylinositol metabolic process
KQY30_RS01050	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KQY30_RS01095	COG0375	protein maturation
KQY30_RS01100	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KQY30_RS01105	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
KQY30_RS01115	COG0409	Hydrogenase expression formation protein
KQY30_RS01195	COG0825	malonyl-CoA metabolic process
KQY30_RS01195	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KQY30_RS01200	COG0318	PFAM AMP-dependent synthetase and ligase
KQY30_RS01210	COG2186	Transcriptional regulator
KQY30_RS01215	COG0656	L-ascorbic acid biosynthetic process
KQY30_RS01220	COG2814	Major facilitator Superfamily
KQY30_RS01230	COG0254	rRNA binding
KQY30_RS01235	COG0588	phosphoglycerate mutase activity
KQY30_RS01245	COG1278	Cold shock
KQY30_RS01285	COG0135	phosphoribosylanthranilate isomerase activity
KQY30_RS01290	COG1960	acyl-CoA dehydrogenase activity
KQY30_RS01295	COG0662	Cupin 2, conserved barrel domain protein
KQY30_RS01300	COG0159	tryptophan synthase activity
KQY30_RS01305	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KQY30_RS01320	COG2030	dehydratase
KQY30_RS01325	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KQY30_RS01345	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KQY30_RS01375	COG2267	carboxylic ester hydrolase activity
KQY30_RS01450	COG3424	synthase
KQY30_RS01460	COG0702	epimerase
KQY30_RS01470	COG0789	Transcriptional regulator
KQY30_RS01490	COG1132	(ABC) transporter
KQY30_RS01495	COG1522	sequence-specific DNA binding
KQY30_RS01530	COG1879	ABC-type sugar transport system periplasmic component
KQY30_RS01535	COG1172	Belongs to the binding-protein-dependent transport system permease family
KQY30_RS01545	COG1129	ABC transporter
KQY30_RS01550	COG4952	isomerase
KQY30_RS01555	COG1028	Short-chain dehydrogenase reductase Sdr
KQY30_RS01555	COG3347	Dehydrogenase
KQY30_RS01560	COG1070	Carbohydrate kinase
KQY30_RS01565	COG1609	Transcriptional regulator
KQY30_RS01595	COG2018	Roadblock/LC7 domain
KQY30_RS01615	COG4941	Belongs to the sigma-70 factor family
KQY30_RS01645	COG3239	Fatty acid desaturase
KQY30_RS01650	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KQY30_RS01665	COG1012	belongs to the aldehyde dehydrogenase family
KQY30_RS01700	COG0583	DNA-binding transcription factor activity
KQY30_RS01710	COG1028	Short-chain dehydrogenase reductase Sdr
KQY30_RS01720	COG0492	ferredoxin-NADP+ reductase activity
KQY30_RS01725	COG2409	Drug exporters of the RND superfamily
KQY30_RS01745	COG3629	intracellular signal transduction
KQY30_RS01745	COG3903	Transcriptional regulator
KQY30_RS01775	COG2801	Transposase and inactivated derivatives
KQY30_RS01775	COG3415	Transposase
KQY30_RS01835	COG1012	belongs to the aldehyde dehydrogenase family
KQY30_RS01870	COG1250	3-hydroxyacyl-CoA dehydrogenase
KQY30_RS01890	COG0318	PFAM AMP-dependent synthetase and ligase
KQY30_RS01910	COG0604	alcohol dehydrogenase
KQY30_RS01910	COG0604	alcohol dehydrogenase
KQY30_RS01910	COG3321	synthase
KQY30_RS01910	COG3321	synthase
KQY30_RS01965	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KQY30_RS01970	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KQY30_RS02010	COG0604	alcohol dehydrogenase
KQY30_RS02020	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KQY30_RS02045	COG1819	glycosyl
KQY30_RS02050	COG2272	Belongs to the type-B carboxylesterase lipase family
KQY30_RS02060	COG2272	Belongs to the type-B carboxylesterase lipase family
KQY30_RS02105	COG0720	synthase
KQY30_RS02110	COG0602	queuosine metabolic process
KQY30_RS02115	COG0302	gtp cyclohydrolase
KQY30_RS02125	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KQY30_RS02130	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KQY30_RS02135	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KQY30_RS02160	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KQY30_RS02180	COG0800	Aldolase
KQY30_RS02190	COG4948	Mandelate Racemase Muconate Lactonizing
KQY30_RS02195	COG2186	Transcriptional regulator
KQY30_RS02210	COG0395	ABC-type sugar transport system, permease component
KQY30_RS02225	COG3345	alpha-galactosidase
KQY30_RS02245	COG1960	acyl-CoA dehydrogenase activity
KQY30_RS02250	COG1960	acyl-CoA dehydrogenase activity
KQY30_RS02270	COG1125	glycine betaine transport
KQY30_RS02270	COG0517	IMP dehydrogenase activity
KQY30_RS02280	COG1174	glycine betaine transport
KQY30_RS02290	COG2124	cytochrome p450
KQY30_RS02300	COG0640	Transcriptional regulator
KQY30_RS02330	COG3835	regulator
KQY30_RS02335	COG0443	Heat shock 70 kDa protein
KQY30_RS02340	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KQY30_RS02355	COG0542	response to heat
KQY30_RS02370	COG4221	oxidoreductase activity
KQY30_RS02380	COG4221	oxidoreductase activity
KQY30_RS02385	COG0667	Aldo Keto reductase
KQY30_RS02430	COG3903	Transcriptional regulator
KQY30_RS02430	COG3629	intracellular signal transduction
KQY30_RS02440	COG2124	cytochrome p450
KQY30_RS02450	COG0477	Major facilitator Superfamily
KQY30_RS02520	COG1028	Short-chain dehydrogenase reductase Sdr
KQY30_RS02540	COG3321	synthase
KQY30_RS02540	COG0604	alcohol dehydrogenase
KQY30_RS02550	COG3209	COG3209 Rhs family protein
KQY30_RS02565	COG4106	trans-aconitate 2-methyltransferase activity
KQY30_RS02580	COG0477	Major facilitator Superfamily
KQY30_RS02610	COG4249	Peptidase C14 caspase catalytic subunit p20
KQY30_RS02610	COG2319	Wd-40 repeat
KQY30_RS02645	COG3959	Transketolase, thiamine diphosphate binding domain
KQY30_RS02650	COG1252	NADH dehydrogenase
KQY30_RS02670	COG0693	protein deglycase activity
KQY30_RS02675	COG0765	amino acid transport
KQY30_RS02680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KQY30_RS02695	COG0765	amino acid transport
KQY30_RS02700	COG1126	abc transporter atp-binding protein
KQY30_RS02705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KQY30_RS02710	COG0531	amino acid
KQY30_RS02735	COG1316	TRANSCRIPTIONal
KQY30_RS02780	COG2318	DinB family
KQY30_RS02805	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KQY30_RS02810	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KQY30_RS02840	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KQY30_RS02845	COG0121	glutamine amidotransferase
KQY30_RS02850	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
KQY30_RS02880	COG0395	ABC-type sugar transport system, permease component
KQY30_RS02885	COG1175	transmembrane transport
KQY30_RS02890	COG2182	Extracellular solute-binding protein
KQY30_RS02895	COG2188	Transcriptional regulator
KQY30_RS02900	COG2188	Transcriptional regulator
KQY30_RS02910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KQY30_RS02915	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KQY30_RS02920	COG1053	succinate dehydrogenase
KQY30_RS03005	COG3275	phosphorelay sensor kinase activity
KQY30_RS03010	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KQY30_RS03020	COG3279	Response regulator of the LytR AlgR family
KQY30_RS03030	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KQY30_RS03095	COG3321	synthase
KQY30_RS03095	COG0604	alcohol dehydrogenase
KQY30_RS03100	COG3250	beta-galactosidase activity
KQY30_RS03105	COG1609	Transcriptional regulator
KQY30_RS03110	COG1879	ABC-type sugar transport system periplasmic component
KQY30_RS03115	COG1129	ABC transporter
KQY30_RS03120	COG1172	Belongs to the binding-protein-dependent transport system permease family
KQY30_RS03125	COG1172	Belongs to the binding-protein-dependent transport system permease family
KQY30_RS03130	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KQY30_RS03135	COG0297	glycogen (starch) synthase activity
KQY30_RS03170	COG1175	transmembrane transport
KQY30_RS03175	COG0395	ABC-type sugar transport system, permease component
KQY30_RS03190	COG1063	alcohol dehydrogenase
KQY30_RS03210	COG1349	DNA-binding transcription factor activity
KQY30_RS03215	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KQY30_RS03315	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
KQY30_RS03325	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KQY30_RS03330	COG2124	cytochrome p450
KQY30_RS03360	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KQY30_RS03365	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KQY30_RS03370	COG1132	(ABC) transporter
KQY30_RS03375	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KQY30_RS03380	COG3251	PFAM MbtH domain protein
KQY30_RS03390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KQY30_RS03395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KQY30_RS03400	COG1120	ATPase activity
KQY30_RS03410	COG3486	L-lysine 6-monooxygenase (NADPH) activity
KQY30_RS03420	COG1879	ABC-type sugar transport system periplasmic component
KQY30_RS03425	COG1172	Belongs to the binding-protein-dependent transport system permease family
KQY30_RS03430	COG1129	ABC transporter
KQY30_RS03435	COG1012	belongs to the aldehyde dehydrogenase family
KQY30_RS03460	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KQY30_RS03465	COG2144	transferase activity, transferring acyl groups
KQY30_RS03485	COG2072	flavoprotein involved in K transport
KQY30_RS03530	COG3142	Participates in the control of copper homeostasis
KQY30_RS03540	COG1940	carbohydrate kinase activity
KQY30_RS03540	COG1846	Transcriptional regulator
KQY30_RS03565	COG1940	carbohydrate kinase activity
KQY30_RS03570	COG0515	serine threonine protein kinase
KQY30_RS03570	COG2815	serine threonine protein kinase
KQY30_RS03590	COG1556	Lactate utilization protein
KQY30_RS03595	COG1139	Iron-sulfur cluster binding protein
KQY30_RS03600	COG0247	lactate metabolic process
KQY30_RS03635	COG2267	carboxylic ester hydrolase activity
KQY30_RS03640	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KQY30_RS03640	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KQY30_RS03650	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KQY30_RS03655	COG1993	acr, cog1993
KQY30_RS03660	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KQY30_RS03670	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KQY30_RS03680	COG4335	DNA alkylation repair
KQY30_RS03695	COG0477	Major facilitator Superfamily
KQY30_RS03700	COG2345	Transcriptional regulator
KQY30_RS03705	COG2084	Dehydrogenase
KQY30_RS03710	COG2124	cytochrome p450
KQY30_RS03750	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KQY30_RS03755	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KQY30_RS03765	COG0438	transferase activity, transferring glycosyl groups
KQY30_RS03785	COG1595	DNA-templated transcription, initiation
KQY30_RS03800	COG2226	methyltransferase
KQY30_RS03810	COG2814	Major facilitator Superfamily
KQY30_RS03845	COG3903	Transcriptional regulator
KQY30_RS03845	COG3629	intracellular signal transduction
KQY30_RS03870	COG3959	Transketolase, thiamine diphosphate binding domain
KQY30_RS03875	COG3958	Transketolase
KQY30_RS03885	COG0583	DNA-binding transcription factor activity
KQY30_RS03890	COG0667	Aldo Keto reductase
KQY30_RS03895	COG3507	Belongs to the glycosyl hydrolase 43 family
KQY30_RS03915	COG1116	anion transmembrane transporter activity
KQY30_RS03925	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KQY30_RS03930	COG1609	Transcriptional regulator
KQY30_RS03955	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KQY30_RS03965	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KQY30_RS03975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KQY30_RS04005	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KQY30_RS04020	COG2755	lipolytic protein G-D-S-L family
KQY30_RS04030	COG2365	Tyrosine phosphatase family
KQY30_RS04035	COG1404	Belongs to the peptidase S8 family
KQY30_RS04060	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KQY30_RS04065	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KQY30_RS04075	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KQY30_RS04090	COG1233	COG1233 Phytoene dehydrogenase and related
KQY30_RS04100	COG1562	ergosterol biosynthetic process
KQY30_RS04105	COG1388	LysM domain
KQY30_RS04105	COG1134	teichoic acid transport
KQY30_RS04125	COG0371	Dehydrogenase
KQY30_RS04150	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
KQY30_RS04160	COG1024	Enoyl-CoA hydratase
KQY30_RS04170	COG0488	(ABC) transporter
KQY30_RS04185	COG2936	dipeptidyl-peptidase activity
KQY30_RS04210	COG4221	oxidoreductase activity
KQY30_RS04220	COG0789	Transcriptional regulator
KQY30_RS04225	COG1250	3-hydroxyacyl-CoA dehydrogenase
KQY30_RS04225	COG1024	Enoyl-CoA hydratase
KQY30_RS04230	COG0183	Belongs to the thiolase family
KQY30_RS04235	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KQY30_RS04240	COG1515	deoxyribonuclease V activity
KQY30_RS04255	COG0488	(ABC) transporter
KQY30_RS04260	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KQY30_RS04315	COG1793	dna ligase
KQY30_RS04340	COG3012	SEC-C Motif Domain Protein
KQY30_RS04350	COG1414	Transcriptional regulator
KQY30_RS04380	COG4214	carbohydrate transport
KQY30_RS04410	COG1940	carbohydrate kinase activity
KQY30_RS04435	COG1063	alcohol dehydrogenase
KQY30_RS04490	COG1686	Belongs to the peptidase S11 family
KQY30_RS04495	COG1357	PFAM Pentapeptide repeats (8 copies)
KQY30_RS04505	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KQY30_RS04530	COG2186	Transcriptional regulator
KQY30_RS04540	COG1175	transmembrane transport
KQY30_RS04545	COG0395	ABC-type sugar transport system, permease component
KQY30_RS04560	COG2159	amidohydrolase
KQY30_RS04565	COG3384	dioxygenase
KQY30_RS04580	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KQY30_RS04590	COG3842	ATPase activity
KQY30_RS04605	COG1840	ABC-type Fe3 transport system, periplasmic component
KQY30_RS04620	COG4638	Rieske (2fe-2S)
KQY30_RS04640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KQY30_RS04650	COG0179	Fumarylacetoacetate (FAA) hydrolase
KQY30_RS04655	COG1840	ABC-type Fe3 transport system, periplasmic component
KQY30_RS04675	COG1131	(ABC) transporter
KQY30_RS04700	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KQY30_RS04725	COG0745	RESPONSE REGULATOR receiver
KQY30_RS04730	COG2205	protein histidine kinase activity
KQY30_RS04735	COG2814	Major facilitator Superfamily
KQY30_RS04740	COG1028	Short-chain dehydrogenase reductase Sdr
KQY30_RS04755	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KQY30_RS04760	COG2264	protein methyltransferase activity
KQY30_RS04765	COG3961	Belongs to the TPP enzyme family
KQY30_RS04770	COG3961	Belongs to the TPP enzyme family
KQY30_RS04775	COG3835	regulator
KQY30_RS04810	COG2186	Transcriptional regulator
KQY30_RS04820	COG4948	Mandelate Racemase Muconate Lactonizing
KQY30_RS04830	COG1175	transmembrane transport
KQY30_RS04835	COG0395	ABC-type sugar transport system, permease component
KQY30_RS04840	COG0657	acetylesterase activity
KQY30_RS04855	COG0667	Aldo Keto reductase
KQY30_RS04890	COG3903	Transcriptional regulator
KQY30_RS04890	COG3629	intracellular signal transduction
KQY30_RS04895	COG4585	Histidine kinase
KQY30_RS04920	COG0477	Major facilitator Superfamily
KQY30_RS04935	COG1902	pentaerythritol trinitrate reductase activity
KQY30_RS04950	COG2197	response regulator
KQY30_RS05015	COG0156	8-amino-7-oxononanoate synthase activity
KQY30_RS05025	COG1024	Enoyl-CoA hydratase
KQY30_RS05030	COG1024	Enoyl-CoA hydratase
KQY30_RS05075	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KQY30_RS05095	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KQY30_RS05100	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KQY30_RS05130	COG0508	dehydrogenase complex catalyzes the overall conversion of
KQY30_RS05140	COG3622	Belongs to the hyi family
KQY30_RS05150	COG0179	Fumarylacetoacetate (FAA) hydrolase
KQY30_RS05155	COG0129	dihydroxy-acid dehydratase activity
KQY30_RS05180	COG3467	pyridoxamine 5'-phosphate
KQY30_RS05185	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KQY30_RS05190	COG1121	(ABC) transporter
KQY30_RS05200	COG0803	Belongs to the bacterial solute-binding protein 9 family
KQY30_RS05230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KQY30_RS05235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KQY30_RS05285	COG1595	DNA-templated transcription, initiation
KQY30_RS05305	COG1733	regulation of RNA biosynthetic process
KQY30_RS05395	COG0464	growth
KQY30_RS05485	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KQY30_RS05540	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KQY30_RS05570	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KQY30_RS05585	COG0028	Belongs to the TPP enzyme family
KQY30_RS05620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KQY30_RS05630	COG0765	amino acid transport
KQY30_RS05655	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
KQY30_RS05660	COG1028	Short-chain dehydrogenase reductase Sdr
KQY30_RS05675	COG0673	inositol 2-dehydrogenase activity
KQY30_RS05735	COG2272	Belongs to the type-B carboxylesterase lipase family
KQY30_RS05770	COG2197	response regulator
KQY30_RS05815	COG1131	(ABC) transporter
KQY30_RS05820	COG1725	Transcriptional regulator
KQY30_RS05855	COG1028	Short-chain dehydrogenase reductase Sdr
KQY30_RS05925	COG1012	belongs to the aldehyde dehydrogenase family
KQY30_RS05935	COG0045	succinate-CoA ligase (ADP-forming) activity
KQY30_RS05940	COG0028	Belongs to the TPP enzyme family
KQY30_RS05945	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KQY30_RS05955	COG2223	nitrite transmembrane transporter activity
KQY30_RS05960	COG2223	nitrite transmembrane transporter activity
KQY30_RS05995	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KQY30_RS06015	COG0673	inositol 2-dehydrogenase activity
KQY30_RS06025	COG1172	Belongs to the binding-protein-dependent transport system permease family
KQY30_RS06030	COG1129	ABC transporter
KQY30_RS06040	COG1940	carbohydrate kinase activity
KQY30_RS06050	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KQY30_RS06065	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KQY30_RS06070	COG3383	formate dehydrogenase (NAD+) activity
KQY30_RS06085	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KQY30_RS06095	COG0583	DNA-binding transcription factor activity
KQY30_RS06105	COG0656	L-ascorbic acid biosynthetic process
KQY30_RS06115	COG2154	pterin-4-alpha-carbinolamine dehydratase
KQY30_RS06125	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KQY30_RS06155	COG0395	ABC-type sugar transport system, permease component
KQY30_RS06160	COG1175	transmembrane transport
KQY30_RS06170	COG1609	Transcriptional regulator
KQY30_RS06190	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
KQY30_RS06240	COG4106	trans-aconitate 2-methyltransferase activity
KQY30_RS06250	COG0457	Tetratricopeptide repeat
KQY30_RS06265	COG1619	proteins homologs of microcin C7 resistance protein MccF
KQY30_RS06275	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KQY30_RS06280	COG2362	D-Aminopeptidase
KQY30_RS06320	COG2172	sigma factor antagonist activity
KQY30_RS06320	COG2208	phosphoserine phosphatase activity
KQY30_RS06320	COG1366	Belongs to the anti-sigma-factor antagonist family
KQY30_RS06335	COG1250	3-hydroxyacyl-CoA dehydrogenase
KQY30_RS06345	COG0604	alcohol dehydrogenase
KQY30_RS06350	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KQY30_RS06350	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KQY30_RS06355	COG2301	Belongs to the HpcH HpaI aldolase family
KQY30_RS06365	COG1960	acyl-CoA dehydrogenase activity
KQY30_RS06370	COG0688	phosphatidylethanolamine metabolic process
KQY30_RS06385	COG1929	Belongs to the glycerate kinase type-1 family
KQY30_RS06400	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KQY30_RS06405	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KQY30_RS06415	COG0281	malic enzyme
KQY30_RS06420	COG0114	fumarate hydratase activity
KQY30_RS06425	COG1271	oxidase subunit
KQY30_RS06440	COG2837	iron assimilation
KQY30_RS06455	COG2323	membrane
KQY30_RS06475	COG1309	transcriptional regulator
KQY30_RS06555	COG2188	Transcriptional regulator
KQY30_RS06610	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
KQY30_RS06620	COG0483	inositol monophosphate 1-phosphatase activity
KQY30_RS06650	COG1953	Uracil, thiamine, allantoin
KQY30_RS06660	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KQY30_RS06665	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KQY30_RS06695	COG0405	Gamma-glutamyltransferase
KQY30_RS06705	COG0765	amino acid transport
KQY30_RS06710	COG0765	amino acid transport
KQY30_RS06715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KQY30_RS06735	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KQY30_RS06750	COG1968	undecaprenyl-diphosphatase activity
KQY30_RS06760	COG0477	Major facilitator Superfamily
KQY30_RS06780	COG1940	carbohydrate kinase activity
KQY30_RS06785	COG1129	ABC transporter
KQY30_RS06800	COG2188	Transcriptional regulator
KQY30_RS06805	COG0673	inositol 2-dehydrogenase activity
KQY30_RS06815	COG4266	Belongs to the allantoicase family
KQY30_RS06820	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KQY30_RS06825	COG1414	Transcriptional regulator
KQY30_RS06840	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KQY30_RS06905	COG1733	regulation of RNA biosynthetic process
KQY30_RS06910	COG0477	Major facilitator Superfamily
KQY30_RS06935	COG2351	hydroxyisourate hydrolase activity
KQY30_RS06955	COG1834	amidinotransferase
KQY30_RS06960	COG3622	Belongs to the hyi family
KQY30_RS06965	COG2084	Dehydrogenase
KQY30_RS06970	COG3960	tartronate-semialdehyde synthase activity
KQY30_RS06995	COG0028	Belongs to the TPP enzyme family
KQY30_RS07000	COG0318	PFAM AMP-dependent synthetase and ligase
KQY30_RS07005	COG0516	GMP reductase activity
KQY30_RS07005	COG0517	IMP dehydrogenase activity
KQY30_RS07010	COG1063	alcohol dehydrogenase
KQY30_RS07015	COG0516	GMP reductase activity
KQY30_RS07015	COG0517	IMP dehydrogenase activity
KQY30_RS07030	COG2197	response regulator
KQY30_RS07065	COG2706	6-phosphogluconolactonase activity
KQY30_RS07105	COG1132	(ABC) transporter
KQY30_RS07110	COG1132	(ABC) transporter
KQY30_RS07135	COG2124	cytochrome p450
KQY30_RS07140	COG2124	cytochrome p450
KQY30_RS07185	COG1162	GTPase activity
KQY30_RS07210	COG0366	Alpha amylase catalytic
KQY30_RS07230	COG5002	protein histidine kinase activity
KQY30_RS07235	COG0745	RESPONSE REGULATOR receiver
KQY30_RS07265	COG2815	serine threonine protein kinase
KQY30_RS07265	COG0515	serine threonine protein kinase
KQY30_RS07275	COG1960	acyl-CoA dehydrogenase activity
KQY30_RS07300	COG0175	sulfate reduction
KQY30_RS07305	COG0529	Catalyzes the synthesis of activated sulfate
KQY30_RS07325	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
KQY30_RS07330	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KQY30_RS07370	COG1175	transmembrane transport
KQY30_RS07425	COG0346	lactoylglutathione lyase activity
KQY30_RS07445	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KQY30_RS07450	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KQY30_RS07475	COG2326	polyphosphate kinase activity
KQY30_RS07505	COG3220	belongs to the UPF0276 family
KQY30_RS07520	COG3253	May function as heme-dependent peroxidase
KQY30_RS07525	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KQY30_RS07535	COG0446	pyridine nucleotide-disulphide oxidoreductase
KQY30_RS07540	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KQY30_RS07560	COG0183	Belongs to the thiolase family
KQY30_RS07565	COG1024	Enoyl-CoA hydratase
KQY30_RS07565	COG1250	3-hydroxyacyl-CoA dehydrogenase
KQY30_RS07585	COG0531	amino acid
KQY30_RS07590	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KQY30_RS07595	COG4214	carbohydrate transport
KQY30_RS07605	COG4213	ABC transporter substrate-binding protein
KQY30_RS07610	COG1940	carbohydrate kinase activity
KQY30_RS07615	COG0395	ABC-type sugar transport system, permease component
KQY30_RS07620	COG1175	transmembrane transport
KQY30_RS07625	COG1653	transport
KQY30_RS07635	COG3903	Transcriptional regulator
KQY30_RS07635	COG3629	intracellular signal transduction
KQY30_RS07650	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KQY30_RS07680	COG1309	transcriptional regulator
KQY30_RS07685	COG0406	alpha-ribazole phosphatase activity
KQY30_RS07690	COG1070	Carbohydrate kinase
KQY30_RS07695	COG1349	DNA-binding transcription factor activity
KQY30_RS07715	COG0395	ABC-type sugar transport system, permease component
KQY30_RS07720	COG1175	transmembrane transport
KQY30_RS07730	COG3250	beta-galactosidase activity
KQY30_RS07735	COG3540	Alkaline phosphatase
KQY30_RS07740	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KQY30_RS07790	COG1024	Enoyl-CoA hydratase
KQY30_RS07805	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KQY30_RS07815	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KQY30_RS07825	COG2040	homocysteine
KQY30_RS07845	COG1799	cell septum assembly
KQY30_RS07865	COG1175	transmembrane transport
KQY30_RS07870	COG0395	ABC-type sugar transport system, permease component
KQY30_RS07890	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KQY30_RS07925	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KQY30_RS07930	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
KQY30_RS07935	COG2080	2 iron, 2 sulfur cluster binding
KQY30_RS07945	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KQY30_RS07950	COG0531	amino acid
KQY30_RS07955	COG0569	domain protein
KQY30_RS07985	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
KQY30_RS07990	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
KQY30_RS07995	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
KQY30_RS08010	COG0756	dUTP diphosphatase activity
KQY30_RS08030	COG2205	protein histidine kinase activity
KQY30_RS08035	COG0745	RESPONSE REGULATOR receiver
KQY30_RS08045	COG0483	inositol monophosphate 1-phosphatase activity
KQY30_RS08050	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KQY30_RS08075	COG1435	thymidine kinase activity
KQY30_RS08095	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KQY30_RS08100	COG1802	Transcriptional regulator
KQY30_RS08110	COG0612	Peptidase, M16
KQY30_RS08115	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KQY30_RS08135	COG0366	Alpha amylase catalytic
KQY30_RS08140	COG0395	ABC-type sugar transport system, permease component
KQY30_RS08145	COG1175	transmembrane transport
KQY30_RS08150	COG2182	Extracellular solute-binding protein
KQY30_RS08165	COG3290	protein histidine kinase activity
KQY30_RS08170	COG4565	transcriptional regulatory protein
KQY30_RS08175	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KQY30_RS08185	COG2197	response regulator
KQY30_RS08190	COG4585	Histidine kinase
KQY30_RS08200	COG0187	DNA topoisomerase II activity
KQY30_RS08215	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KQY30_RS08220	COG2186	Transcriptional regulator
KQY30_RS08225	COG3842	ATPase activity
KQY30_RS08335	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KQY30_RS08375	COG2045	Belongs to the ComB family
KQY30_RS08380	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KQY30_RS08385	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KQY30_RS08390	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KQY30_RS08425	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KQY30_RS08435	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KQY30_RS08440	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KQY30_RS08450	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KQY30_RS08470	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KQY30_RS08480	COG2205	protein histidine kinase activity
KQY30_RS08485	COG0745	RESPONSE REGULATOR receiver
KQY30_RS08490	COG1126	abc transporter atp-binding protein
KQY30_RS08495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KQY30_RS08500	COG0765	amino acid transport
KQY30_RS08505	COG0765	amino acid transport
KQY30_RS08510	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KQY30_RS08530	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KQY30_RS08560	COG0583	DNA-binding transcription factor activity
KQY30_RS08570	COG1917	Cupin 2, conserved barrel domain protein
KQY30_RS08570	COG2207	Transcriptional regulator
KQY30_RS08580	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KQY30_RS08590	COG0783	Belongs to the Dps family
KQY30_RS08595	COG1396	sequence-specific DNA binding
KQY30_RS08600	COG1058	Belongs to the CinA family
KQY30_RS08600	COG1546	Belongs to the CinA family
KQY30_RS08610	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KQY30_RS08630	COG3437	response regulator, receiver
KQY30_RS08630	COG3850	Histidine kinase
KQY30_RS08630	COG4999	Histidine kinase
KQY30_RS08630	COG2205	protein histidine kinase activity
KQY30_RS08630	COG3437	response regulator, receiver
KQY30_RS08630	COG3850	Histidine kinase
KQY30_RS08630	COG2205	protein histidine kinase activity
KQY30_RS08630	COG4999	Histidine kinase
KQY30_RS08635	COG2770	Histidine kinase
KQY30_RS08635	COG2208	phosphoserine phosphatase activity
KQY30_RS08660	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KQY30_RS08665	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KQY30_RS08670	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
KQY30_RS08685	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KQY30_RS08690	COG0612	Peptidase, M16
KQY30_RS08695	COG1185	polyribonucleotide nucleotidyltransferase activity
KQY30_RS08700	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KQY30_RS08710	COG1674	ftsk spoiiie
KQY30_RS08730	COG1404	Belongs to the peptidase S8 family
KQY30_RS08735	COG3266	domain, Protein
KQY30_RS08750	COG0455	bacterial-type flagellum organization
KQY30_RS08755	COG0747	negative chemotaxis
KQY30_RS08760	COG0601	transmembrane transport
KQY30_RS08765	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KQY30_RS08770	COG0444	Belongs to the ABC transporter superfamily
KQY30_RS08775	COG4608	Belongs to the ABC transporter superfamily
KQY30_RS08785	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KQY30_RS08790	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KQY30_RS08800	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KQY30_RS08815	COG0779	Required for maturation of 30S ribosomal subunits
KQY30_RS08830	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
KQY30_RS08835	COG0442	prolyl-tRNA aminoacylation
KQY30_RS08850	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KQY30_RS08855	COG0750	zinc metalloprotease
KQY30_RS08860	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KQY30_RS08880	COG1012	belongs to the aldehyde dehydrogenase family
KQY30_RS08885	COG2508	Transcriptional regulator
KQY30_RS08920	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KQY30_RS08925	COG1177	transmembrane transport
KQY30_RS08930	COG1176	ABC-type spermidine putrescine transport system, permease component I
KQY30_RS08935	COG3842	ATPase activity
KQY30_RS08940	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KQY30_RS08945	COG1012	belongs to the aldehyde dehydrogenase family
KQY30_RS08960	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KQY30_RS08965	COG0584	glycerophosphoryl diester phosphodiesterase
KQY30_RS08970	COG1012	belongs to the aldehyde dehydrogenase family
KQY30_RS08980	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KQY30_RS08985	COG1136	(ABC) transporter
KQY30_RS08995	COG3842	ATPase activity
KQY30_RS09010	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KQY30_RS09025	COG0233	cytoplasmic translational termination
KQY30_RS09030	COG0528	UMP kinase activity
KQY30_RS09035	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KQY30_RS09040	COG0052	Belongs to the universal ribosomal protein uS2 family
KQY30_RS09055	COG1191	sigma factor activity
KQY30_RS09135	COG0515	serine threonine protein kinase
KQY30_RS09135	COG2815	serine threonine protein kinase
KQY30_RS09145	COG1074	ATP-dependent DNA helicase activity
KQY30_RS09150	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KQY30_RS09170	COG0792	nuclease activity
KQY30_RS09185	COG0681	Belongs to the peptidase S26 family
KQY30_RS09200	COG0681	Belongs to the peptidase S26 family
KQY30_RS09205	COG0335	large ribosomal subunit rRNA binding
KQY30_RS09210	COG0336	Belongs to the RNA methyltransferase TrmD family
KQY30_RS09215	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KQY30_RS09220	COG1837	Belongs to the UPF0109 family
KQY30_RS09225	COG0228	four-way junction DNA binding
KQY30_RS09235	COG2188	Transcriptional regulator
KQY30_RS09255	COG1735	metal-dependent hydrolase with the TIM-barrel fold
KQY30_RS09260	COG0626	cystathionine gamma-synthase activity
KQY30_RS09265	COG3457	Alanine racemase
KQY30_RS09270	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
KQY30_RS09280	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
KQY30_RS09310	COG0477	Major facilitator Superfamily
KQY30_RS09315	COG1196	nuclear chromosome segregation
KQY30_RS09315	COG1196	nuclear chromosome segregation
KQY30_RS09325	COG1254	Belongs to the acylphosphatase family
KQY30_RS09330	COG2340	Cysteine-rich secretory protein family
KQY30_RS09335	COG1733	regulation of RNA biosynthetic process
KQY30_RS09340	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KQY30_RS09345	COG0571	ribonuclease III activity
KQY30_RS09350	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KQY30_RS09365	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KQY30_RS09370	COG0742	ribosomal rna small subunit methyltransferase
KQY30_RS09380	COG1461	Dihydroxyacetone kinase
KQY30_RS09385	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KQY30_RS09390	COG0351	phosphomethylpyrimidine kinase
KQY30_RS09410	COG1181	Belongs to the D-alanine--D-alanine ligase family
KQY30_RS09415	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KQY30_RS09430	COG0776	regulation of translation
KQY30_RS09440	COG0066	3-isopropylmalate dehydratase activity
KQY30_RS09445	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KQY30_RS09450	COG1414	Transcriptional regulator
KQY30_RS09485	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KQY30_RS09490	COG0179	Fumarylacetoacetate (FAA) hydrolase
KQY30_RS09500	COG5002	protein histidine kinase activity
KQY30_RS09505	COG2018	Roadblock/LC7 domain
KQY30_RS09525	COG2018	Roadblock/LC7 domain
KQY30_RS09545	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KQY30_RS09550	COG5492	domain, Protein
KQY30_RS09570	COG1472	Belongs to the glycosyl hydrolase 3 family
KQY30_RS09585	COG1609	Transcriptional regulator
KQY30_RS09595	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KQY30_RS09600	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KQY30_RS09605	COG0473	3-isopropylmalate dehydrogenase activity
KQY30_RS09615	COG0789	Transcriptional regulator
KQY30_RS09635	COG1073	alpha beta
KQY30_RS09640	COG1309	transcriptional regulator
KQY30_RS09655	COG1012	belongs to the aldehyde dehydrogenase family
KQY30_RS09660	COG0506	proline dehydrogenase activity
KQY30_RS09680	COG0477	Major facilitator Superfamily
KQY30_RS09690	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KQY30_RS09695	COG0440	acetolactate synthase activity
KQY30_RS09705	COG5001	Diguanylate cyclase
KQY30_RS09705	COG3300	MHYT domain
KQY30_RS09715	COG0667	Aldo Keto reductase
KQY30_RS09720	COG2133	pyrroloquinoline quinone binding
KQY30_RS09730	COG2197	response regulator
KQY30_RS09745	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KQY30_RS09755	COG1028	Short-chain dehydrogenase reductase Sdr
KQY30_RS09765	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KQY30_RS09770	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KQY30_RS09780	COG0154	amidase activity
KQY30_RS09785	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KQY30_RS09795	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KQY30_RS09805	COG4221	oxidoreductase activity
KQY30_RS09830	COG0482	sulfurtransferase activity
KQY30_RS09850	COG4608	Belongs to the ABC transporter superfamily
KQY30_RS09855	COG0444	Belongs to the ABC transporter superfamily
KQY30_RS09860	COG0601	transmembrane transport
KQY30_RS09865	COG0747	negative chemotaxis
KQY30_RS09890	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KQY30_RS09895	COG0509	glycine decarboxylation via glycine cleavage system
KQY30_RS09900	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KQY30_RS09905	COG1760	l-serine dehydratase
KQY30_RS09910	COG3903	Transcriptional regulator
KQY30_RS09910	COG3629	intracellular signal transduction
KQY30_RS09915	COG1335	isochorismatase
KQY30_RS09930	COG3629	intracellular signal transduction
KQY30_RS09930	COG3903	Transcriptional regulator
KQY30_RS09945	COG0154	amidase activity
KQY30_RS09975	COG0726	polysaccharide deacetylase
KQY30_RS09990	COG1376	ErfK ybiS ycfS ynhG family protein
KQY30_RS09995	COG1376	ErfK ybiS ycfS ynhG family protein
KQY30_RS10010	COG2197	response regulator
KQY30_RS10015	COG4585	Histidine kinase
KQY30_RS10030	COG1132	(ABC) transporter
KQY30_RS10035	COG1132	(ABC) transporter
KQY30_RS10040	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KQY30_RS10065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KQY30_RS10075	COG0058	SHG alpha-glucan phosphorylase activity
KQY30_RS10080	COG0366	Alpha amylase catalytic
KQY30_RS10085	COG0366	Alpha amylase catalytic
KQY30_RS10090	COG3281	Trehalose synthase
KQY30_RS10095	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KQY30_RS10115	COG3118	belongs to the thioredoxin family
KQY30_RS10140	COG2124	cytochrome p450
KQY30_RS10145	COG4948	Mandelate Racemase Muconate Lactonizing
KQY30_RS10150	COG1301	dicarboxylic acid transport
KQY30_RS10155	COG3290	protein histidine kinase activity
KQY30_RS10160	COG4565	transcriptional regulatory protein
KQY30_RS10170	COG1175	transmembrane transport
KQY30_RS10175	COG0395	ABC-type sugar transport system, permease component
KQY30_RS10180	COG0205	6-phosphofructokinase activity
KQY30_RS10185	COG0857	belongs to the CobB CobQ family
KQY30_RS10185	COG0280	phosphate acetyltransferase
KQY30_RS10230	COG0842	Transport permease protein
KQY30_RS10245	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KQY30_RS10245	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KQY30_RS10330	COG2205	protein histidine kinase activity
KQY30_RS10335	COG0745	RESPONSE REGULATOR receiver
KQY30_RS10350	COG0183	Belongs to the thiolase family
KQY30_RS10370	COG1131	(ABC) transporter
KQY30_RS10405	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
KQY30_RS10420	COG1250	3-hydroxyacyl-CoA dehydrogenase
KQY30_RS10440	COG3920	Histidine kinase
KQY30_RS10460	COG2197	response regulator
KQY30_RS10465	COG4585	Histidine kinase
KQY30_RS10475	COG0789	Transcriptional regulator
KQY30_RS10515	COG2197	response regulator
KQY30_RS10530	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KQY30_RS10535	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KQY30_RS10540	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KQY30_RS10545	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KQY30_RS10550	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KQY30_RS10555	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KQY30_RS10560	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KQY30_RS10580	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KQY30_RS10585	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KQY30_RS10595	COG2890	protein-(glutamine-N5) methyltransferase activity
KQY30_RS10600	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KQY30_RS10605	COG0254	rRNA binding
KQY30_RS10610	COG1316	TRANSCRIPTIONal
KQY30_RS10620	COG0083	homoserine kinase activity
KQY30_RS10625	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KQY30_RS10630	COG0460	homoserine dehydrogenase
KQY30_RS10635	COG0019	diaminopimelate decarboxylase activity
KQY30_RS10640	COG0018	arginyl-trna synthetase
KQY30_RS10645	COG0745	RESPONSE REGULATOR receiver
KQY30_RS10675	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KQY30_RS10720	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KQY30_RS10785	COG2072	flavoprotein involved in K transport
KQY30_RS10790	COG0745	RESPONSE REGULATOR receiver
KQY30_RS10795	COG1846	Transcriptional regulator
KQY30_RS10800	COG1028	Short-chain dehydrogenase reductase Sdr
KQY30_RS10845	COG2843	Capsule synthesis protein
KQY30_RS10885	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KQY30_RS10895	COG0768	penicillin binding
KQY30_RS10900	COG0768	penicillin binding
KQY30_RS10905	COG0768	penicillin binding
KQY30_RS10910	COG1686	Belongs to the peptidase S11 family
KQY30_RS10925	COG1012	belongs to the aldehyde dehydrogenase family
KQY30_RS10930	COG3491	Belongs to the iron ascorbate-dependent oxidoreductase family
KQY30_RS10935	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KQY30_RS10980	COG1309	transcriptional regulator
KQY30_RS11000	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
KQY30_RS11005	COG1793	dna ligase
KQY30_RS11005	COG3285	dna ligase
KQY30_RS11030	COG0772	Belongs to the SEDS family
KQY30_RS11035	COG0768	penicillin binding
KQY30_RS11040	COG0154	amidase activity
KQY30_RS11060	COG3883	PFAM NLP P60 protein
KQY30_RS11060	COG0791	NLP P60 protein
KQY30_RS11150	COG0745	RESPONSE REGULATOR receiver
KQY30_RS11155	COG2205	protein histidine kinase activity
KQY30_RS11160	COG0567	Dehydrogenase, E1 component
KQY30_RS11160	COG0508	dehydrogenase complex catalyzes the overall conversion of
KQY30_RS11180	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
KQY30_RS11215	COG2255	four-way junction helicase activity
KQY30_RS11275	COG0604	alcohol dehydrogenase
KQY30_RS11280	COG0281	malic enzyme
KQY30_RS11295	COG1126	abc transporter atp-binding protein
KQY30_RS11300	COG4106	trans-aconitate 2-methyltransferase activity
KQY30_RS11350	COG0142	geranyltranstransferase activity
KQY30_RS11355	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KQY30_RS11395	COG1597	lipid kinase activity
KQY30_RS11420	COG0395	ABC-type sugar transport system, permease component
KQY30_RS11425	COG1175	transmembrane transport
KQY30_RS11430	COG2182	Extracellular solute-binding protein
KQY30_RS11435	COG2188	Transcriptional regulator
KQY30_RS11460	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KQY30_RS11485	COG0242	peptide deformylase activity
KQY30_RS11505	COG5662	AntiSigma factor
KQY30_RS11510	COG1595	DNA-templated transcription, initiation
KQY30_RS11520	COG2135	peptidase activity
KQY30_RS11530	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KQY30_RS11540	COG2076	Multidrug Resistance protein
KQY30_RS11550	COG0483	inositol monophosphate 1-phosphatase activity
KQY30_RS11560	COG0753	catalase activity
KQY30_RS11585	COG1615	UPF0182 protein
KQY30_RS11595	COG3480	Lon protease (S16) C-terminal proteolytic domain
KQY30_RS11645	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KQY30_RS11695	COG0210	DNA helicase
KQY30_RS11755	COG0601	transmembrane transport
KQY30_RS11760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KQY30_RS11805	COG0513	Belongs to the DEAD box helicase family
KQY30_RS11815	COG1432	Conserved Protein
KQY30_RS11840	COG0598	Magnesium transport protein CorA
KQY30_RS11875	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KQY30_RS11880	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KQY30_RS11890	COG1595	DNA-templated transcription, initiation
KQY30_RS11905	COG1024	Enoyl-CoA hydratase
KQY30_RS11910	COG0519	Catalyzes the synthesis of GMP from XMP
KQY30_RS11925	COG1611	Belongs to the LOG family
KQY30_RS11930	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KQY30_RS11980	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KQY30_RS11995	COG4608	Belongs to the ABC transporter superfamily
KQY30_RS12005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KQY30_RS12010	COG0601	transmembrane transport
KQY30_RS12030	COG4608	Belongs to the ABC transporter superfamily
KQY30_RS12035	COG0444	Belongs to the ABC transporter superfamily
KQY30_RS12040	COG0601	transmembrane transport
KQY30_RS12045	COG0747	negative chemotaxis
KQY30_RS12050	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KQY30_RS12055	COG1217	gtp-binding protein TYPA
KQY30_RS12075	COG1053	succinate dehydrogenase
KQY30_RS12095	COG1175	transmembrane transport
KQY30_RS12100	COG0395	ABC-type sugar transport system, permease component
KQY30_RS12125	COG1842	Phage shock protein A
KQY30_RS12205	COG0012	GTP binding
KQY30_RS12220	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KQY30_RS12230	COG1722	exodeoxyribonuclease VII activity
KQY30_RS12255	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
KQY30_RS12255	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
KQY30_RS12260	COG0114	fumarate hydratase activity
KQY30_RS12280	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KQY30_RS12285	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KQY30_RS12305	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KQY30_RS12310	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KQY30_RS12315	COG0667	Aldo Keto reductase
KQY30_RS12320	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KQY30_RS12355	COG2885	chlorophyll binding
KQY30_RS12375	COG2197	response regulator
KQY30_RS12410	COG2894	cell division
KQY30_RS12455	COG0515	serine threonine protein kinase
KQY30_RS12455	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KQY30_RS12460	COG2610	gluconate transmembrane transporter activity
KQY30_RS12465	COG0251	oxidation-reduction process
KQY30_RS12470	COG1414	Transcriptional regulator
KQY30_RS12490	COG1487	ribonuclease activity
KQY30_RS12510	COG0436	Aminotransferase
KQY30_RS12570	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
KQY30_RS12580	COG0477	Major facilitator Superfamily
KQY30_RS12585	COG1309	transcriptional regulator
KQY30_RS12595	COG0367	asparagine synthase
KQY30_RS12640	COG0463	Glycosyl transferase, family 2
KQY30_RS12655	COG1331	Highly conserved protein containing a thioredoxin domain
KQY30_RS12680	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KQY30_RS12690	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KQY30_RS12705	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KQY30_RS12715	COG1595	DNA-templated transcription, initiation
KQY30_RS12735	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KQY30_RS12750	COG1028	Short-chain dehydrogenase reductase Sdr
KQY30_RS12760	COG1733	regulation of RNA biosynthetic process
KQY30_RS12770	COG0584	glycerophosphoryl diester phosphodiesterase
KQY30_RS12780	COG1028	Short-chain dehydrogenase reductase Sdr
KQY30_RS12785	COG0702	epimerase
KQY30_RS12850	COG1595	DNA-templated transcription, initiation
KQY30_RS12860	COG1131	(ABC) transporter
KQY30_RS12875	COG0488	(ABC) transporter
KQY30_RS12915	COG0454	-acetyltransferase
KQY30_RS12915	COG0456	acetyltransferase
KQY30_RS12920	COG1136	(ABC) transporter
KQY30_RS12930	COG1376	ErfK ybiS ycfS ynhG family protein
KQY30_RS12945	COG2986	histidine ammonia-lyase
KQY30_RS12965	COG1024	Enoyl-CoA hydratase
KQY30_RS12980	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KQY30_RS12995	COG1309	transcriptional regulator
KQY30_RS13000	COG0424	maF-like protein
KQY30_RS13010	COG4770	biotin carboxylase activity
KQY30_RS13040	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KQY30_RS13055	COG1012	belongs to the aldehyde dehydrogenase family
KQY30_RS13060	COG1012	belongs to the aldehyde dehydrogenase family
KQY30_RS13075	COG1595	DNA-templated transcription, initiation
KQY30_RS13080	COG0745	RESPONSE REGULATOR receiver
KQY30_RS13085	COG2205	protein histidine kinase activity
KQY30_RS13110	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KQY30_RS13120	COG0583	DNA-binding transcription factor activity
KQY30_RS13125	COG2814	Major facilitator Superfamily
KQY30_RS13155	COG1079	Belongs to the binding-protein-dependent transport system permease family
KQY30_RS13160	COG4603	Belongs to the binding-protein-dependent transport system permease family
KQY30_RS13165	COG3845	ABC transporter
KQY30_RS13170	COG1744	ABC transporter substrate-binding protein PnrA-like
KQY30_RS13175	COG1473	amidohydrolase
KQY30_RS13175	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
KQY30_RS13180	COG0326	Molecular chaperone. Has ATPase activity
KQY30_RS13205	COG1595	DNA-templated transcription, initiation
KQY30_RS13220	COG2089	acid synthase
KQY30_RS13235	COG1216	Glycosyl transferase, family 2
KQY30_RS13250	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KQY30_RS13250	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KQY30_RS13265	COG1595	DNA-templated transcription, initiation
KQY30_RS13285	COG2009	succinate dehydrogenase
KQY30_RS13295	COG1053	succinate dehydrogenase
KQY30_RS13300	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KQY30_RS13310	COG1309	transcriptional regulator
KQY30_RS13335	COG0745	RESPONSE REGULATOR receiver
KQY30_RS13340	COG2205	protein histidine kinase activity
KQY30_RS13350	COG1408	metallophosphoesterase
KQY30_RS13355	COG1686	Belongs to the peptidase S11 family
KQY30_RS13380	COG0180	Tryptophanyl-tRNA synthetase
KQY30_RS13385	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KQY30_RS13390	COG0754	glutathionylspermidine amidase activity
KQY30_RS13405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KQY30_RS13410	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KQY30_RS13415	COG0039	L-malate dehydrogenase activity
KQY30_RS13440	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KQY30_RS13450	COG0138	bifunctional purine biosynthesis protein purh
KQY30_RS13480	COG0045	succinate-CoA ligase (ADP-forming) activity
KQY30_RS13485	COG3552	Protein containing von Willebrand factor type A (VWA) domain
KQY30_RS13490	COG2425	protein containing a von Willebrand factor type A (vWA) domain
KQY30_RS13495	COG0714	Associated with various cellular activities
KQY30_RS13515	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KQY30_RS13515	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KQY30_RS13525	COG0739	heme binding
KQY30_RS13545	COG0791	NLP P60 protein
KQY30_RS13555	COG2197	response regulator
KQY30_RS13580	COG0519	Catalyzes the synthesis of GMP from XMP
KQY30_RS13580	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KQY30_RS13595	COG1012	belongs to the aldehyde dehydrogenase family
KQY30_RS13610	COG0515	serine threonine protein kinase
KQY30_RS13625	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KQY30_RS13640	COG2337	Toxic component of a toxin-antitoxin (TA) module
KQY30_RS13645	COG0516	GMP reductase activity
KQY30_RS13655	COG1595	DNA-templated transcription, initiation
KQY30_RS13660	COG2197	response regulator
KQY30_RS13670	COG0583	DNA-binding transcription factor activity
KQY30_RS13680	COG2132	Multicopper oxidase
KQY30_RS13685	COG4221	oxidoreductase activity
KQY30_RS13705	COG0726	polysaccharide deacetylase
KQY30_RS13725	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KQY30_RS13750	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KQY30_RS13775	COG0802	atpase or kinase
KQY30_RS13785	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KQY30_RS13795	COG0736	holo-[acyl-carrier-protein] synthase activity
KQY30_RS13800	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KQY30_RS13805	COG1072	(Pantothenic acid kinase))
KQY30_RS13815	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KQY30_RS13820	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KQY30_RS13825	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KQY30_RS13830	COG0488	(ABC) transporter
KQY30_RS13850	COG0101	tRNA pseudouridine synthase activity
KQY30_RS13855	COG0203	ribosomal protein L17
KQY30_RS13860	COG0202	RNA polymerase activity
KQY30_RS13865	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KQY30_RS13870	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KQY30_RS13875	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KQY30_RS13880	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KQY30_RS13890	COG0563	adenylate kinase activity
KQY30_RS13900	COG0200	Binds to the 23S rRNA
KQY30_RS13905	COG1841	ribosomal large subunit assembly
KQY30_RS13910	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KQY30_RS13915	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KQY30_RS13920	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KQY30_RS13925	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KQY30_RS13930	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KQY30_RS13935	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KQY30_RS13940	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KQY30_RS13945	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KQY30_RS13950	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KQY30_RS13955	COG0255	Belongs to the universal ribosomal protein uL29 family
KQY30_RS13960	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KQY30_RS13965	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KQY30_RS13970	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KQY30_RS13975	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KQY30_RS13980	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KQY30_RS13985	COG0089	rRNA binding
KQY30_RS13990	COG0088	Forms part of the polypeptide exit tunnel
KQY30_RS13995	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KQY30_RS14000	COG0051	transcription antitermination factor activity, RNA binding
KQY30_RS14015	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KQY30_RS14025	COG0049	tRNA binding
KQY30_RS14030	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KQY30_RS14035	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KQY30_RS14040	COG0085	RNA polymerase activity
KQY30_RS14045	COG0222	ribosome binding
KQY30_RS14050	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KQY30_RS14060	COG0081	regulation of translation
KQY30_RS14065	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KQY30_RS14075	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KQY30_RS14085	COG0436	Aminotransferase
KQY30_RS14090	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KQY30_RS14095	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KQY30_RS14100	COG0477	Major facilitator Superfamily
KQY30_RS14115	COG2030	dehydratase
KQY30_RS14120	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KQY30_RS14140	COG0702	epimerase
KQY30_RS14150	COG1666	GTP binding
KQY30_RS14155	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KQY30_RS14165	COG2261	transglycosylase associated protein
KQY30_RS14170	COG3304	Inner membrane component domain
KQY30_RS14175	COG0501	Belongs to the peptidase M48B family
KQY30_RS14180	COG1007	ATP synthesis coupled electron transport
KQY30_RS14190	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KQY30_RS14195	COG0713	ATP synthesis coupled electron transport
KQY30_RS14200	COG0839	Belongs to the complex I subunit 6 family
KQY30_RS14205	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KQY30_RS14210	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
KQY30_RS14215	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KQY30_RS14220	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KQY30_RS14225	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KQY30_RS14245	COG0674	pyruvate-flavodoxin oxidoreductase activity
KQY30_RS14245	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KQY30_RS14250	COG1013	pyruvate-flavodoxin oxidoreductase activity
KQY30_RS14255	COG1733	regulation of RNA biosynthetic process
KQY30_RS14260	COG0702	epimerase
KQY30_RS14285	COG4935	Belongs to the peptidase S8 family
KQY30_RS14285	COG2234	aminopeptidase activity
KQY30_RS14295	COG1131	(ABC) transporter
KQY30_RS14305	COG0142	geranyltranstransferase activity
KQY30_RS14310	COG0179	Fumarylacetoacetate (FAA) hydrolase
KQY30_RS14315	COG1007	ATP synthesis coupled electron transport
KQY30_RS14325	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KQY30_RS14330	COG0713	ATP synthesis coupled electron transport
KQY30_RS14335	COG0839	Belongs to the complex I subunit 6 family
KQY30_RS14340	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KQY30_RS14345	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
KQY30_RS14350	COG1034	ATP synthesis coupled electron transport
KQY30_RS14355	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KQY30_RS14365	COG0649	NAD binding
KQY30_RS14370	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KQY30_RS14375	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KQY30_RS14405	COG2226	methyltransferase
KQY30_RS14415	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
KQY30_RS14425	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
KQY30_RS14430	COG1278	Cold shock
KQY30_RS14450	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
KQY30_RS14460	COG0163	prenyltransferase activity
KQY30_RS14470	COG0109	protoheme IX farnesyltransferase activity
KQY30_RS14475	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
KQY30_RS14485	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KQY30_RS14490	COG1333	cytochrome c biogenesis protein
KQY30_RS14510	COG0406	alpha-ribazole phosphatase activity
KQY30_RS14515	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KQY30_RS14615	COG1742	UPF0060 membrane protein
KQY30_RS14625	COG1690	Belongs to the RtcB family
KQY30_RS14645	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
KQY30_RS14650	COG0018	arginyl-trna synthetase
KQY30_RS14655	COG0113	porphobilinogen synthase activity
KQY30_RS14660	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KQY30_RS14660	COG1648	precorrin-2 dehydrogenase activity
KQY30_RS14665	COG0181	hydroxymethylbilane synthase activity
KQY30_RS14670	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KQY30_RS14675	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KQY30_RS14725	COG0123	including yeast histone deacetylase and acetoin utilization protein
KQY30_RS14730	COG2223	nitrite transmembrane transporter activity
KQY30_RS14735	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KQY30_RS14755	COG0180	Tryptophanyl-tRNA synthetase
KQY30_RS14760	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KQY30_RS14770	COG0842	Transport permease protein
KQY30_RS14770	COG1129	ABC transporter
KQY30_RS14795	COG0129	dihydroxy-acid dehydratase activity
KQY30_RS14805	COG1082	Xylose isomerase domain protein TIM barrel
KQY30_RS14810	COG0248	Ppx GppA phosphatase
KQY30_RS14830	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
KQY30_RS14840	COG1194	a g-specific adenine glycosylase
KQY30_RS14845	COG1595	DNA-templated transcription, initiation
KQY30_RS14855	COG0745	RESPONSE REGULATOR receiver
KQY30_RS14860	COG2205	protein histidine kinase activity
KQY30_RS14865	COG0346	lactoylglutathione lyase activity
KQY30_RS14885	COG0739	heme binding
KQY30_RS14905	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
KQY30_RS14925	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KQY30_RS14935	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KQY30_RS14940	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KQY30_RS14955	COG2197	response regulator
KQY30_RS14970	COG0649	NAD binding
KQY30_RS14980	COG1732	Glycine betaine
KQY30_RS14985	COG1174	glycine betaine transport
KQY30_RS14990	COG1174	glycine betaine transport
KQY30_RS14995	COG0517	IMP dehydrogenase activity
KQY30_RS14995	COG1125	glycine betaine transport
KQY30_RS15015	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KQY30_RS15020	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KQY30_RS15030	COG0302	gtp cyclohydrolase
KQY30_RS15045	COG0037	tRNA processing
KQY30_RS15055	COG2027	D-alanyl-D-alanine carboxypeptidase
KQY30_RS15060	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KQY30_RS15070	COG0586	Pfam SNARE associated Golgi protein
KQY30_RS15075	COG0076	glutamate decarboxylase activity
KQY30_RS15095	COG1012	belongs to the aldehyde dehydrogenase family
KQY30_RS15130	COG0110	maltose O-acetyltransferase activity
KQY30_RS15145	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KQY30_RS15145	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KQY30_RS15160	COG2172	sigma factor antagonist activity
KQY30_RS15160	COG1366	Belongs to the anti-sigma-factor antagonist family
KQY30_RS15160	COG2208	phosphoserine phosphatase activity
KQY30_RS15180	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KQY30_RS15205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KQY30_RS15325	COG0739	heme binding
KQY30_RS15325	COG1196	nuclear chromosome segregation
KQY30_RS15325	COG0741	lytic transglycosylase activity
KQY30_RS15355	COG3903	Transcriptional regulator
KQY30_RS15355	COG3629	intracellular signal transduction
KQY30_RS15405	COG2311	Membrane
KQY30_RS15435	COG0596	Alpha beta hydrolase
KQY30_RS15440	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KQY30_RS15445	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KQY30_RS15455	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KQY30_RS15455	COG1754	DNA topoisomerase type I activity
KQY30_RS15465	COG2890	protein-(glutamine-N5) methyltransferase activity
KQY30_RS15475	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
KQY30_RS15485	COG1366	Belongs to the anti-sigma-factor antagonist family
KQY30_RS15490	COG1111	helicase
KQY30_RS15490	COG1205	dead DEAH box helicase
KQY30_RS15555	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KQY30_RS15560	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KQY30_RS15570	COG2267	carboxylic ester hydrolase activity
KQY30_RS15595	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KQY30_RS15625	COG0003	Pfam Anion-transporting ATPase
KQY30_RS15635	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KQY30_RS15745	COG0519	Catalyzes the synthesis of GMP from XMP
KQY30_RS15760	COG1104	cysteine desulfurase activity
KQY30_RS15765	COG1061	Type III restriction enzyme res subunit
KQY30_RS15845	COG1051	belongs to the nudix hydrolase family
KQY30_RS15855	COG0105	UTP biosynthetic process
KQY30_RS15935	COG1132	(ABC) transporter
KQY30_RS15960	COG1028	Short-chain dehydrogenase reductase Sdr
KQY30_RS15980	COG1376	ErfK ybiS ycfS ynhG family protein
KQY30_RS15990	COG0640	Transcriptional regulator
KQY30_RS16020	COG1595	DNA-templated transcription, initiation
KQY30_RS16040	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KQY30_RS16045	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KQY30_RS16060	COG0463	Glycosyl transferase, family 2
KQY30_RS16065	COG1802	Transcriptional regulator
KQY30_RS16070	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KQY30_RS16100	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KQY30_RS16115	COG1131	(ABC) transporter
KQY30_RS16120	COG3559	Exporter of polyketide antibiotics
KQY30_RS16130	COG2197	response regulator
KQY30_RS16135	COG4585	Histidine kinase
KQY30_RS16145	COG3844	kynureninase activity
KQY30_RS16165	COG0477	Major facilitator Superfamily
KQY30_RS16170	COG0191	fructose-bisphosphate aldolase activity
KQY30_RS16175	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KQY30_RS16190	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KQY30_RS16210	COG0542	response to heat
KQY30_RS16230	COG0789	Transcriptional regulator
KQY30_RS16235	COG0484	heat shock protein binding
KQY30_RS16240	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KQY30_RS16245	COG0443	Heat shock 70 kDa protein
KQY30_RS16250	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KQY30_RS16255	COG0247	lactate metabolic process
KQY30_RS16255	COG2181	nitrate reductase activity
KQY30_RS16270	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
KQY30_RS16275	COG0717	Belongs to the dCTP deaminase family
KQY30_RS16355	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KQY30_RS16395	COG0187	DNA topoisomerase II activity
KQY30_RS16450	COG4989	oxidoreductase activity
KQY30_RS16495	COG0604	alcohol dehydrogenase
KQY30_RS16555	COG2815	serine threonine protein kinase
KQY30_RS16555	COG0515	serine threonine protein kinase
KQY30_RS16640	COG2197	response regulator
KQY30_RS16655	COG1136	(ABC) transporter
KQY30_RS16655	COG0577	efflux transmembrane transporter activity
KQY30_RS16720	COG1064	alcohol dehydrogenase
KQY30_RS16730	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KQY30_RS16735	COG3903	Transcriptional regulator
KQY30_RS16735	COG3629	intracellular signal transduction
KQY30_RS16820	COG2268	Band 7 protein
KQY30_RS16860	COG1733	regulation of RNA biosynthetic process
KQY30_RS16890	COG0300	oxidoreductase activity
KQY30_RS16955	COG0667	Aldo Keto reductase
KQY30_RS16965	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KQY30_RS17025	COG1028	Short-chain dehydrogenase reductase Sdr
KQY30_RS17080	COG2205	protein histidine kinase activity
KQY30_RS17085	COG0745	RESPONSE REGULATOR receiver
KQY30_RS17090	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KQY30_RS17105	COG1595	DNA-templated transcription, initiation
KQY30_RS17110	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KQY30_RS17125	COG1396	sequence-specific DNA binding
KQY30_RS17130	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
KQY30_RS17145	COG1960	acyl-CoA dehydrogenase activity
KQY30_RS17150	COG1362	aminopeptidase activity
KQY30_RS17190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KQY30_RS17200	COG4221	oxidoreductase activity
KQY30_RS17205	COG0508	dehydrogenase complex catalyzes the overall conversion of
KQY30_RS17210	COG0022	dehydrogenase e1 component
KQY30_RS17235	COG0515	serine threonine protein kinase
KQY30_RS17240	COG0515	serine threonine protein kinase
KQY30_RS17255	COG4591	ABC-type transport system involved in lipoprotein release permease component
KQY30_RS17255	COG1136	(ABC) transporter
KQY30_RS17275	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KQY30_RS17280	COG0303	'Molybdopterin
KQY30_RS17305	COG1522	sequence-specific DNA binding
KQY30_RS17310	COG1309	transcriptional regulator
KQY30_RS17315	COG1250	3-hydroxyacyl-CoA dehydrogenase
KQY30_RS17340	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KQY30_RS17355	COG1733	regulation of RNA biosynthetic process
KQY30_RS17360	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KQY30_RS17370	COG1716	ATPase activity
KQY30_RS17375	COG1716	ATPase activity
KQY30_RS17395	COG0515	serine threonine protein kinase
KQY30_RS17400	COG3764	Sortase (surface protein transpeptidase)
KQY30_RS17405	COG3764	Sortase (surface protein transpeptidase)
KQY30_RS17430	COG0705	Rhomboid family
KQY30_RS17450	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KQY30_RS17450	COG2755	lipolytic protein G-D-S-L family
KQY30_RS17535	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KQY30_RS17545	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
KQY30_RS17550	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KQY30_RS17555	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KQY30_RS17560	COG0592	DNA-directed DNA polymerase activity
KQY30_RS17570	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KQY30_RS17575	COG0594	ribonuclease P activity
KQY30_RS17580	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
KQY30_RS17585	COG0706	membrane insertase activity
KQY30_RS17595	COG0357	Ribosomal RNA small subunit methyltransferase G
KQY30_RS17600	COG1192	Involved in chromosome partitioning
KQY30_RS17615	COG3118	belongs to the thioredoxin family
KQY30_RS17620	COG0492	ferredoxin-NADP+ reductase activity
KQY30_RS17630	COG1595	DNA-templated transcription, initiation
KQY30_RS17635	COG0515	serine threonine protein kinase
KQY30_RS17635	COG2815	serine threonine protein kinase
KQY30_RS17650	COG0617	tRNA 3'-terminal CCA addition
KQY30_RS17670	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KQY30_RS17695	COG0360	Binds together with S18 to 16S ribosomal RNA
KQY30_RS17700	COG0629	single-stranded DNA binding
KQY30_RS17705	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KQY30_RS17710	COG0359	binds to the 23S rRNA
KQY30_RS17730	COG0305	Participates in initiation and elongation during chromosome replication
KQY30_RS17855	COG0626	cystathionine gamma-synthase activity
KQY30_RS17860	COG1950	PFAM Membrane protein of
KQY30_RS17865	COG0662	Cupin 2, conserved barrel domain protein
KQY30_RS17885	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KQY30_RS17895	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KQY30_RS17900	COG1609	Transcriptional regulator
KQY30_RS17905	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KQY30_RS17910	COG1271	oxidase subunit
KQY30_RS17915	COG1294	oxidase, subunit
KQY30_RS17920	COG4988	ABC transporter
KQY30_RS17930	COG0561	phosphatase activity
KQY30_RS17940	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
KQY30_RS17960	COG1131	(ABC) transporter
KQY30_RS17970	COG1131	(ABC) transporter
KQY30_RS17985	COG0561	phosphatase activity
KQY30_RS17990	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KQY30_RS18000	COG2837	iron assimilation
KQY30_RS18005	COG2372	response to copper ion
KQY30_RS18030	COG0006	proline dipeptidase activity
KQY30_RS18050	COG0653	protein targeting
KQY30_RS18075	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KQY30_RS18110	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KQY30_RS18110	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KQY30_RS18175	COG2188	Transcriptional regulator
KQY30_RS18245	COG0277	FAD linked oxidase domain protein
KQY30_RS18285	COG0477	Major facilitator Superfamily
KQY30_RS18310	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KQY30_RS18320	COG0596	Alpha beta hydrolase
KQY30_RS18350	COG2755	lipolytic protein G-D-S-L family
KQY30_RS18365	COG0596	Alpha beta hydrolase
KQY30_RS18400	COG1819	glycosyl
KQY30_RS18405	COG2130	NADP-dependent
KQY30_RS18410	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KQY30_RS18415	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KQY30_RS18420	COG2867	negative regulation of translational initiation
KQY30_RS18430	COG2197	response regulator
KQY30_RS18450	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KQY30_RS18455	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KQY30_RS18495	COG1595	DNA-templated transcription, initiation
KQY30_RS18500	COG0318	PFAM AMP-dependent synthetase and ligase
KQY30_RS18560	COG0745	RESPONSE REGULATOR receiver
KQY30_RS18565	COG2205	protein histidine kinase activity
KQY30_RS18575	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KQY30_RS18575	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KQY30_RS18585	COG3467	pyridoxamine 5'-phosphate
KQY30_RS18590	COG2353	YceI-like domain
KQY30_RS18610	COG1191	sigma factor activity
KQY30_RS18615	COG1191	sigma factor activity
KQY30_RS18650	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KQY30_RS18690	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KQY30_RS18730	COG1028	Short-chain dehydrogenase reductase Sdr
KQY30_RS18745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KQY30_RS18785	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KQY30_RS18800	COG0702	epimerase
KQY30_RS18810	COG0179	Fumarylacetoacetate (FAA) hydrolase
KQY30_RS18835	COG1028	Short-chain dehydrogenase reductase Sdr
KQY30_RS18930	COG1595	DNA-templated transcription, initiation
KQY30_RS18945	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KQY30_RS18980	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KQY30_RS19005	COG0151	Belongs to the GarS family
KQY30_RS19020	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KQY30_RS19050	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KQY30_RS19055	COG0047	phosphoribosylformylglycinamidine synthase activity
KQY30_RS19060	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KQY30_RS19065	COG0456	acetyltransferase
KQY30_RS19065	COG1846	Transcriptional regulator
KQY30_RS19085	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
KQY30_RS19135	COG0785	Cytochrome C biogenesis protein
KQY30_RS19185	COG0513	Belongs to the DEAD box helicase family
KQY30_RS19245	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KQY30_RS19285	COG1396	sequence-specific DNA binding
KQY30_RS19285	COG3800	Transcriptional regulator
KQY30_RS19305	COG0579	oxidoreductase
KQY30_RS19350	COG1846	Transcriptional regulator
KQY30_RS19420	COG1196	nuclear chromosome segregation
KQY30_RS19420	COG0741	lytic transglycosylase activity
KQY30_RS19420	COG0739	heme binding
KQY30_RS19425	COG0671	phosphoesterase, PA-phosphatase related
KQY30_RS19440	COG0277	FAD linked oxidase domain protein
KQY30_RS19455	COG1937	Protein conserved in bacteria
KQY30_RS19465	COG0306	phosphate transporter
KQY30_RS19485	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KQY30_RS19490	COG0494	nUDIX hydrolase
KQY30_RS19490	COG0406	alpha-ribazole phosphatase activity
KQY30_RS19505	COG0456	acetyltransferase
KQY30_RS19510	COG0737	Belongs to the 5'-nucleotidase family
KQY30_RS19530	COG0181	hydroxymethylbilane synthase activity
KQY30_RS19605	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KQY30_RS19610	COG1609	Transcriptional regulator
KQY30_RS19615	COG0745	RESPONSE REGULATOR receiver
KQY30_RS19640	COG2897	thiosulfate sulfurtransferase activity
KQY30_RS19675	COG3485	protocatechuate 3,4-dioxygenase
KQY30_RS19680	COG0735	belongs to the Fur family
KQY30_RS19690	COG1490	D-aminoacyl-tRNA deacylase activity
KQY30_RS19705	COG4552	Acetyltransferase involved in intracellular survival and related
KQY30_RS19725	COG3973	AAA domain
KQY30_RS19740	COG1902	pentaerythritol trinitrate reductase activity
KQY30_RS19765	COG0640	Transcriptional regulator
KQY30_RS19770	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KQY30_RS19780	COG3848	Pyruvate phosphate dikinase
KQY30_RS19780	COG0574	Belongs to the PEP-utilizing enzyme family
KQY30_RS19815	COG0438	transferase activity, transferring glycosyl groups
KQY30_RS19845	COG2207	Transcriptional regulator
KQY30_RS19855	COG0588	phosphoglycerate mutase activity
KQY30_RS19875	COG5002	protein histidine kinase activity
KQY30_RS19890	COG1329	Transcriptional regulator
KQY30_RS19895	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KQY30_RS19900	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KQY30_RS19910	COG0215	cysteine-tRNA ligase activity
KQY30_RS19915	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KQY30_RS19925	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KQY30_RS19935	COG3842	ATPase activity
KQY30_RS19990	COG1061	Type III restriction enzyme res subunit
KQY30_RS20240	COG1573	uracil-dna glycosylase
KQY30_RS20250	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KQY30_RS20330	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KQY30_RS20400	COG0463	Glycosyl transferase, family 2
KQY30_RS20410	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KQY30_RS20470	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KQY30_RS20475	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
KQY30_RS20525	COG0702	epimerase
KQY30_RS20535	COG1309	transcriptional regulator
KQY30_RS20565	COG1061	Type III restriction enzyme res subunit
KQY30_RS20605	COG1120	ATPase activity
KQY30_RS20610	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KQY30_RS20615	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KQY30_RS20635	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
KQY30_RS20640	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KQY30_RS20650	COG2814	Major facilitator Superfamily
KQY30_RS20675	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KQY30_RS20705	COG0667	Aldo Keto reductase
KQY30_RS20710	COG2267	carboxylic ester hydrolase activity
KQY30_RS20730	COG0640	Transcriptional regulator
KQY30_RS20740	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KQY30_RS20750	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KQY30_RS20760	COG0247	lactate metabolic process
KQY30_RS20760	COG0277	FAD linked oxidase domain protein
KQY30_RS20795	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KQY30_RS20845	COG1028	Short-chain dehydrogenase reductase Sdr
KQY30_RS20905	COG0259	pyridoxamine-phosphate oxidase activity
KQY30_RS20925	COG4821	SIS domain
KQY30_RS20935	COG2945	thiolester hydrolase activity
KQY30_RS20935	COG0596	Alpha beta hydrolase
KQY30_RS21025	COG2072	flavoprotein involved in K transport
KQY30_RS21030	COG0259	pyridoxamine-phosphate oxidase activity
KQY30_RS21035	COG1309	transcriptional regulator
KQY30_RS21045	COG0515	serine threonine protein kinase
KQY30_RS21045	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KQY30_RS21110	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
KQY30_RS21125	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KQY30_RS21150	COG1686	Belongs to the peptidase S11 family
KQY30_RS21175	COG0577	efflux transmembrane transporter activity
KQY30_RS21180	COG0577	efflux transmembrane transporter activity
KQY30_RS21180	COG1136	(ABC) transporter
KQY30_RS21190	COG2197	response regulator
KQY30_RS21220	COG1028	Short-chain dehydrogenase reductase Sdr
KQY30_RS21225	COG0318	PFAM AMP-dependent synthetase and ligase
KQY30_RS21250	COG3384	dioxygenase
KQY30_RS21265	COG0477	Major facilitator Superfamily
KQY30_RS21270	COG1349	DNA-binding transcription factor activity
KQY30_RS21275	COG1105	Belongs to the carbohydrate kinase PfkB family
KQY30_RS21290	COG3191	aminopeptidase activity
KQY30_RS21300	COG1970	mechanosensitive ion channel activity
KQY30_RS21310	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KQY30_RS21335	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KQY30_RS21340	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KQY30_RS21350	COG0315	cyclic pyranopterin monophosphate synthase activity
KQY30_RS21355	COG0521	Mo-molybdopterin cofactor biosynthetic process
KQY30_RS21355	COG0315	cyclic pyranopterin monophosphate synthase activity
KQY30_RS21395	COG2732	(Barnase) inhibitor
KQY30_RS21440	COG3903	Transcriptional regulator
KQY30_RS21440	COG3629	intracellular signal transduction
KQY30_RS21470	COG0438	transferase activity, transferring glycosyl groups
KQY30_RS21485	COG0728	peptidoglycan biosynthetic process
KQY30_RS21495	COG0438	transferase activity, transferring glycosyl groups
KQY30_RS21550	COG0708	Exodeoxyribonuclease III
KQY30_RS21560	COG2072	flavoprotein involved in K transport
KQY30_RS21565	COG2267	carboxylic ester hydrolase activity
KQY30_RS21585	COG2409	Drug exporters of the RND superfamily
KQY30_RS21595	COG0310	cobalt ion transport
KQY30_RS21605	COG1122	ATPase activity
KQY30_RS21610	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KQY30_RS21630	COG0442	prolyl-tRNA aminoacylation
KQY30_RS21695	COG0084	hydrolase, TatD family'
KQY30_RS21705	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KQY30_RS21710	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KQY30_RS21725	COG0488	(ABC) transporter
KQY30_RS21755	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KQY30_RS21760	COG2197	response regulator
KQY30_RS21765	COG1846	Transcriptional regulator
KQY30_RS21770	COG4106	trans-aconitate 2-methyltransferase activity
KQY30_RS21785	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KQY30_RS21795	COG0193	aminoacyl-tRNA hydrolase activity
KQY30_RS21800	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KQY30_RS21805	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KQY30_RS21810	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KQY30_RS21825	COG4585	Histidine kinase
KQY30_RS21850	COG2031	fatty acid transporter
KQY30_RS21860	COG2814	Major facilitator Superfamily
KQY30_RS21865	COG1136	(ABC) transporter
KQY30_RS21870	COG0577	efflux transmembrane transporter activity
KQY30_RS21930	COG0515	serine threonine protein kinase
KQY30_RS21930	COG2815	serine threonine protein kinase
KQY30_RS21950	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KQY30_RS21970	COG2124	cytochrome p450
KQY30_RS21985	COG0148	phosphopyruvate hydratase activity
KQY30_RS22010	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KQY30_RS22015	COG0577	efflux transmembrane transporter activity
KQY30_RS22015	COG1136	(ABC) transporter
KQY30_RS22020	COG1136	(ABC) transporter
KQY30_RS22050	COG0183	Belongs to the thiolase family
KQY30_RS22055	COG2755	lipolytic protein G-D-S-L family
KQY30_RS22075	COG1174	glycine betaine transport
KQY30_RS22080	COG1174	glycine betaine transport
KQY30_RS22110	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KQY30_RS22115	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KQY30_RS22125	COG1228	amidohydrolase
KQY30_RS22155	COG0726	polysaccharide deacetylase
KQY30_RS22180	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KQY30_RS22185	COG1191	sigma factor activity
KQY30_RS22190	COG1366	Belongs to the anti-sigma-factor antagonist family
KQY30_RS22200	COG0745	RESPONSE REGULATOR receiver
KQY30_RS22205	COG2205	protein histidine kinase activity
KQY30_RS22240	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KQY30_RS22310	COG1316	TRANSCRIPTIONal
KQY30_RS22315	COG1607	acyl-coa hydrolase
KQY30_RS22320	COG0667	Aldo Keto reductase
KQY30_RS22325	COG2207	Transcriptional regulator
KQY30_RS22340	COG1316	TRANSCRIPTIONal
KQY30_RS22345	COG1316	TRANSCRIPTIONal
KQY30_RS22350	COG1316	TRANSCRIPTIONal
KQY30_RS22375	COG0778	Nitroreductase
KQY30_RS22375	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
KQY30_RS22380	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KQY30_RS22415	COG1620	l-lactate permease
KQY30_RS22420	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KQY30_RS22425	COG2835	tetraacyldisaccharide 4'-kinase activity
KQY30_RS22445	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
KQY30_RS22485	COG0714	Associated with various cellular activities
KQY30_RS22505	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KQY30_RS22510	COG0745	RESPONSE REGULATOR receiver
KQY30_RS22515	COG5000	phosphorelay sensor kinase activity
KQY30_RS22515	COG5002	protein histidine kinase activity
KQY30_RS22520	COG0823	Involved in the tonB-independent uptake of proteins
KQY30_RS22530	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KQY30_RS22535	COG2197	response regulator
KQY30_RS22540	COG3214	Protein conserved in bacteria
KQY30_RS22550	COG0653	protein targeting
KQY30_RS22570	COG0693	protein deglycase activity
KQY30_RS22575	COG2902	Dehydrogenase
KQY30_RS22585	COG1134	teichoic acid transport
KQY30_RS22585	COG1388	LysM domain
KQY30_RS22595	COG1309	transcriptional regulator
KQY30_RS22600	COG0395	ABC-type sugar transport system, permease component
KQY30_RS22605	COG1175	transmembrane transport
KQY30_RS22615	COG1674	ftsk spoiiie
KQY30_RS22620	COG0515	serine threonine protein kinase
KQY30_RS22630	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KQY30_RS22645	COG2884	Cell division ATP-binding protein ftsE
KQY30_RS22655	COG0793	Belongs to the peptidase S41A family
KQY30_RS22660	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KQY30_RS22675	COG0583	DNA-binding transcription factor activity
KQY30_RS22700	COG0242	peptide deformylase activity
KQY30_RS22705	COG2223	nitrite transmembrane transporter activity
KQY30_RS22735	COG3973	AAA domain
KQY30_RS22735	COG3973	AAA domain
KQY30_RS22745	COG0776	regulation of translation
KQY30_RS22750	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KQY30_RS22755	COG1678	Uncharacterized ACR, COG1678
KQY30_RS22770	COG1175	transmembrane transport
KQY30_RS22775	COG0395	ABC-type sugar transport system, permease component
KQY30_RS22780	COG3525	Glycosyl hydrolase, family 20, catalytic domain
KQY30_RS22795	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KQY30_RS22860	COG3185	4-Hydroxyphenylpyruvate dioxygenase
KQY30_RS22870	COG0277	FAD linked oxidase domain protein
KQY30_RS22915	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KQY30_RS22925	COG1113	amino acid transport
KQY30_RS22940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KQY30_RS22945	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
KQY30_RS22960	COG1234	tRNA 3'-trailer cleavage
KQY30_RS22965	COG1263	PTS System
KQY30_RS22970	COG1263	PTS System
KQY30_RS22975	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KQY30_RS22980	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KQY30_RS22990	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KQY30_RS23010	COG0477	Major facilitator Superfamily
KQY30_RS23025	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KQY30_RS23030	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KQY30_RS23045	COG4555	ABC transporter
KQY30_RS23060	COG2733	membrane
KQY30_RS23085	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KQY30_RS23085	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KQY30_RS23140	COG4702	Belongs to the UPF0303 family
KQY30_RS23145	COG0673	inositol 2-dehydrogenase activity
KQY30_RS23200	COG3397	chitin binding
KQY30_RS23210	COG3511	phospholipase C
KQY30_RS23225	COG1126	abc transporter atp-binding protein
KQY30_RS23230	COG0765	amino acid transport
KQY30_RS23235	COG0765	amino acid transport
KQY30_RS23240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KQY30_RS23250	COG0154	amidase activity
KQY30_RS23255	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KQY30_RS23270	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KQY30_RS23280	COG0702	epimerase
KQY30_RS23335	COG0406	alpha-ribazole phosphatase activity
KQY30_RS23365	COG0745	RESPONSE REGULATOR receiver
KQY30_RS23405	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KQY30_RS23410	COG4977	sequence-specific DNA binding
KQY30_RS23415	COG0589	response to stress
KQY30_RS23425	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KQY30_RS23445	COG1960	acyl-CoA dehydrogenase activity
KQY30_RS23460	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KQY30_RS23465	COG1309	transcriptional regulator
KQY30_RS23485	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KQY30_RS23495	COG0028	Belongs to the TPP enzyme family
KQY30_RS23520	COG1472	Belongs to the glycosyl hydrolase 3 family
KQY30_RS23530	COG1846	Transcriptional regulator
KQY30_RS23530	COG0456	acetyltransferase
KQY30_RS23535	COG1609	Transcriptional regulator
KQY30_RS23540	COG0673	inositol 2-dehydrogenase activity
KQY30_RS23555	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KQY30_RS23575	COG2409	Drug exporters of the RND superfamily
KQY30_RS23590	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KQY30_RS23590	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
KQY30_RS23600	COG3718	enzyme involved in inositol metabolism
KQY30_RS23605	COG3962	Belongs to the TPP enzyme family
KQY30_RS23615	COG0367	asparagine synthase
KQY30_RS23640	COG2132	Multicopper oxidase
KQY30_RS23655	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
KQY30_RS23660	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
KQY30_RS23665	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
KQY30_RS23680	COG3629	intracellular signal transduction
KQY30_RS23680	COG3903	Transcriptional regulator
KQY30_RS23685	COG2197	response regulator
KQY30_RS23695	COG3963	phosphatidate phosphatase activity
KQY30_RS23730	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KQY30_RS23760	COG0629	single-stranded DNA binding
KQY30_RS23785	COG2346	COG2346, Truncated hemoglobins
KQY30_RS23790	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KQY30_RS23820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KQY30_RS23835	COG1486	melibiose metabolic process
KQY30_RS23840	COG0395	ABC-type sugar transport system, permease component
KQY30_RS23845	COG1175	transmembrane transport
KQY30_RS23855	COG1940	carbohydrate kinase activity
KQY30_RS23860	COG0668	transmembrane transport
KQY30_RS23870	COG3525	Glycosyl hydrolase, family 20, catalytic domain
KQY30_RS23900	COG2337	Toxic component of a toxin-antitoxin (TA) module
KQY30_RS23905	COG2814	Major facilitator Superfamily
KQY30_RS23920	COG0494	nUDIX hydrolase
KQY30_RS23940	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KQY30_RS23945	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KQY30_RS23965	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KQY30_RS23970	COG4552	Acetyltransferase involved in intracellular survival and related
KQY30_RS23980	COG2223	nitrite transmembrane transporter activity
KQY30_RS23995	COG4221	oxidoreductase activity
KQY30_RS24050	COG2172	sigma factor antagonist activity
KQY30_RS24055	COG0475	glutathione-regulated potassium exporter activity
KQY30_RS24075	COG0544	peptidyl-prolyl cis-trans isomerase activity
KQY30_RS24080	COG0740	serine-type endopeptidase activity
KQY30_RS24085	COG0740	serine-type endopeptidase activity
KQY30_RS24090	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KQY30_RS24100	COG0525	valine-tRNA ligase activity
KQY30_RS24105	COG0285	dihydrofolate synthase activity
KQY30_RS24115	COG0105	UTP biosynthetic process
KQY30_RS24120	COG1077	Cell shape determining protein MreB Mrl
KQY30_RS24135	COG0768	penicillin binding
KQY30_RS24140	COG0772	Belongs to the SEDS family
KQY30_RS24160	COG1530	ribonuclease E activity
KQY30_RS24165	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KQY30_RS24170	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KQY30_RS24175	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KQY30_RS24225	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KQY30_RS24235	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KQY30_RS24250	COG0501	Belongs to the peptidase M48B family
KQY30_RS24265	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KQY30_RS24275	COG0799	negative regulation of ribosome biogenesis
KQY30_RS24280	COG0588	phosphoglycerate mutase activity
KQY30_RS24295	COG0477	Major facilitator Superfamily
KQY30_RS24315	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KQY30_RS24325	COG0495	leucyl-tRNA aminoacylation
KQY30_RS24335	COG1307	EDD domain protein, DegV family
KQY30_RS24340	COG1596	polysaccharide export
KQY30_RS24340	COG1555	photosystem II stabilization
KQY30_RS24345	COG1234	tRNA 3'-trailer cleavage
KQY30_RS24350	COG2353	YceI-like domain
KQY30_RS24365	COG0268	Binds directly to 16S ribosomal RNA
KQY30_RS24370	COG0481	GTPase activity
KQY30_RS24410	COG1420	regulation of RNA biosynthetic process
KQY30_RS24415	COG0484	heat shock protein binding
KQY30_RS24430	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KQY30_RS24440	COG0537	adenosine 5'-monophosphoramidase activity
KQY30_RS24445	COG1234	tRNA 3'-trailer cleavage
KQY30_RS24450	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
KQY30_RS24450	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KQY30_RS24470	COG2315	Protein conserved in bacteria
KQY30_RS24480	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KQY30_RS24495	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KQY30_RS24505	COG1381	Involved in DNA repair and RecF pathway recombination
KQY30_RS24510	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KQY30_RS24520	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KQY30_RS24525	COG1121	(ABC) transporter
KQY30_RS24530	COG0803	Belongs to the bacterial solute-binding protein 9 family
KQY30_RS24530	COG3443	Belongs to the bacterial solute-binding protein 9 family
KQY30_RS24535	COG0423	glycine-tRNA ligase activity
KQY30_RS24550	COG0667	Aldo Keto reductase
KQY30_RS24560	COG0477	Major facilitator Superfamily
KQY30_RS24585	COG2188	Transcriptional regulator
KQY30_RS24605	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KQY30_RS24610	COG0546	phosphoglycolate phosphatase activity
KQY30_RS24615	COG0574	Belongs to the PEP-utilizing enzyme family
KQY30_RS24615	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KQY30_RS24645	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KQY30_RS24645	COG2146	nitrite reductase [NAD(P)H] activity
KQY30_RS24665	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KQY30_RS24680	COG0243	molybdopterin cofactor binding
KQY30_RS24685	COG2949	membrane
KQY30_RS24695	COG3552	Protein containing von Willebrand factor type A (VWA) domain
KQY30_RS24700	COG0714	Associated with various cellular activities
KQY30_RS24720	COG0232	Belongs to the dGTPase family. Type 2 subfamily
KQY30_RS24730	COG0358	DNA primase activity
KQY30_RS24735	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KQY30_RS24750	COG1070	Carbohydrate kinase
KQY30_RS24825	COG0629	single-stranded DNA binding
KQY30_RS24990	COG5301	cellulose 1,4-beta-cellobiosidase activity
KQY30_RS25085	COG1764	response to oxidative stress
KQY30_RS25125	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KQY30_RS25130	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KQY30_RS25135	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KQY30_RS25150	COG1741	Belongs to the pirin family
KQY30_RS25165	COG0789	Transcriptional regulator
KQY30_RS25170	COG0667	Aldo Keto reductase
KQY30_RS25185	COG2197	response regulator
KQY30_RS25190	COG4585	Histidine kinase
KQY30_RS25205	COG1309	transcriptional regulator
KQY30_RS25210	COG0477	Major facilitator Superfamily
KQY30_RS25220	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
KQY30_RS25265	COG1358	cellular component organization or biogenesis
KQY30_RS25320	COG3290	protein histidine kinase activity
KQY30_RS25325	COG3608	succinylglutamate desuccinylase aspartoacylase
KQY30_RS25325	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
KQY30_RS25345	COG3608	succinylglutamate desuccinylase aspartoacylase
KQY30_RS25345	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
KQY30_RS25370	COG1472	Belongs to the glycosyl hydrolase 3 family
KQY30_RS25375	COG3833	ABC-type maltose transport systems, permease component
KQY30_RS25380	COG1175	transmembrane transport
KQY30_RS25385	COG1653	transport
KQY30_RS25455	COG4122	O-methyltransferase activity
KQY30_RS25470	COG3845	ABC transporter
KQY30_RS25495	COG1309	transcriptional regulator
KQY30_RS25500	COG0438	transferase activity, transferring glycosyl groups
KQY30_RS25525	COG0860	N-Acetylmuramoyl-L-alanine amidase
KQY30_RS25545	COG2197	response regulator
KQY30_RS25550	COG4585	Histidine kinase
KQY30_RS25560	COG1131	(ABC) transporter
KQY30_RS25575	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KQY30_RS25580	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KQY30_RS25595	COG0800	Aldolase
KQY30_RS25600	COG3022	response to hydroperoxide
KQY30_RS25610	COG2816	NAD+ diphosphatase activity
KQY30_RS25620	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KQY30_RS25995	COG4974	Belongs to the 'phage' integrase family
KQY30_RS26020	COG0662	Cupin 2, conserved barrel domain protein
KQY30_RS26050	COG0738	Major facilitator superfamily
KQY30_RS26090	COG0384	phenazine biosynthesis protein PhzF
KQY30_RS26120	COG0745	RESPONSE REGULATOR receiver
KQY30_RS26125	COG2205	protein histidine kinase activity
KQY30_RS26140	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KQY30_RS26155	COG2814	Major facilitator Superfamily
KQY30_RS26180	COG0672	)-iron permease
KQY30_RS26185	COG2837	iron assimilation
KQY30_RS26195	COG1120	ATPase activity
KQY30_RS26200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KQY30_RS26205	COG4558	Periplasmic binding protein
KQY30_RS26260	COG1994	Peptidase M50
KQY30_RS26280	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KQY30_RS26285	COG0477	Major facilitator Superfamily
KQY30_RS26300	COG2814	Major facilitator Superfamily
KQY30_RS26315	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KQY30_RS26315	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KQY30_RS26345	COG0174	glutamine synthetase
KQY30_RS26355	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KQY30_RS26365	COG1609	Transcriptional regulator
KQY30_RS26370	COG2182	Extracellular solute-binding protein
KQY30_RS26375	COG1175	transmembrane transport
KQY30_RS26385	COG0366	Alpha amylase catalytic
KQY30_RS26400	COG1309	transcriptional regulator
KQY30_RS26425	COG2197	response regulator
KQY30_RS26460	COG0745	RESPONSE REGULATOR receiver
KQY30_RS26515	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KQY30_RS26520	COG0321	lipoyl(octanoyl) transferase activity
KQY30_RS26560	COG2186	Transcriptional regulator
KQY30_RS26575	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
KQY30_RS26585	COG0508	dehydrogenase complex catalyzes the overall conversion of
KQY30_RS26590	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KQY30_RS26595	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KQY30_RS26600	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
KQY30_RS26605	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KQY30_RS26605	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KQY30_RS26610	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
KQY30_RS26625	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KQY30_RS26630	COG1132	(ABC) transporter
KQY30_RS26635	COG2226	methyltransferase
KQY30_RS26655	COG4585	Histidine kinase
KQY30_RS26660	COG2197	response regulator
KQY30_RS26665	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KQY30_RS26670	COG0584	glycerophosphoryl diester phosphodiesterase
KQY30_RS26680	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KQY30_RS26695	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KQY30_RS26705	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KQY30_RS26710	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KQY30_RS26720	COG1376	ErfK ybiS ycfS ynhG family protein
KQY30_RS26730	COG1845	cytochrome c oxidase, subunit III
KQY30_RS26735	COG2010	Cytochrome c
KQY30_RS26740	COG0723	plastoquinol--plastocyanin reductase activity
KQY30_RS26745	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KQY30_RS26750	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KQY30_RS26755	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KQY30_RS26765	COG0705	Rhomboid family
KQY30_RS26785	COG0741	lytic transglycosylase activity
KQY30_RS26785	COG0791	NLP P60 protein
KQY30_RS26800	COG0438	transferase activity, transferring glycosyl groups
KQY30_RS26820	COG0003	Pfam Anion-transporting ATPase
KQY30_RS26830	COG1940	carbohydrate kinase activity
KQY30_RS26855	COG4585	Histidine kinase
KQY30_RS26860	COG2197	response regulator
KQY30_RS26865	COG0205	6-phosphofructokinase activity
KQY30_RS26875	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
KQY30_RS26885	COG2193	ferroxidase activity
KQY30_RS26890	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KQY30_RS26895	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KQY30_RS26900	COG0515	serine threonine protein kinase
KQY30_RS26900	COG2815	serine threonine protein kinase
KQY30_RS26905	COG2022	thiamine diphosphate biosynthetic process
KQY30_RS26915	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KQY30_RS26915	COG2022	thiamine diphosphate biosynthetic process
KQY30_RS26930	COG0352	thiamine-phosphate diphosphorylase activity
KQY30_RS26945	COG1233	COG1233 Phytoene dehydrogenase and related
KQY30_RS26960	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KQY30_RS26980	COG0714	Associated with various cellular activities
KQY30_RS26990	COG0275	rRNA processing
KQY30_RS27000	COG0768	penicillin binding
KQY30_RS27005	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KQY30_RS27015	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KQY30_RS27020	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KQY30_RS27030	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KQY30_RS27035	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KQY30_RS27055	COG1799	cell septum assembly
KQY30_RS27065	COG3599	regulation of cell shape
KQY30_RS27080	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KQY30_RS27130	COG0587	DNA-directed DNA polymerase activity
KQY30_RS27140	COG1432	Conserved Protein
KQY30_RS27160	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KQY30_RS27180	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KQY30_RS27185	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KQY30_RS27190	COG0131	Imidazoleglycerol-phosphate dehydratase
KQY30_RS27200	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KQY30_RS27205	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KQY30_RS27210	COG0251	oxidation-reduction process
KQY30_RS27215	COG0107	imidazoleglycerol-phosphate synthase activity
KQY30_RS27230	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KQY30_RS27235	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KQY30_RS27255	COG0134	indole-3-glycerol-phosphate synthase activity
KQY30_RS27260	COG0133	tryptophan synthase activity
KQY30_RS27265	COG0159	tryptophan synthase activity
KQY30_RS27275	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KQY30_RS27280	COG2301	Belongs to the HpcH HpaI aldolase family
KQY30_RS27285	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KQY30_RS27290	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KQY30_RS27320	COG0067	glutamate synthase
KQY30_RS27320	COG0069	glutamate synthase activity
KQY30_RS27320	COG0070	glutamate synthase
KQY30_RS27340	COG1278	Cold shock
KQY30_RS27345	COG0513	Belongs to the DEAD box helicase family
KQY30_RS27375	COG0287	Prephenate dehydrogenase
KQY30_RS27375	COG1605	Chorismate mutase
KQY30_RS27390	COG0737	Belongs to the 5'-nucleotidase family
KQY30_RS27395	COG2968	Membrane
KQY30_RS27445	COG2050	protein possibly involved in aromatic compounds catabolism
KQY30_RS27465	COG1643	Atp-dependent helicase
KQY30_RS27495	COG0237	dephospho-CoA kinase activity
KQY30_RS27520	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KQY30_RS27550	COG2124	cytochrome p450
KQY30_RS27560	COG0436	Aminotransferase
KQY30_RS27590	COG2313	pseudouridylate synthase activity
KQY30_RS27595	COG1063	alcohol dehydrogenase
KQY30_RS27600	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KQY30_RS27605	COG0584	glycerophosphoryl diester phosphodiesterase
KQY30_RS27615	COG0556	nucleotide-excision repair
KQY30_RS27635	COG1619	proteins homologs of microcin C7 resistance protein MccF
KQY30_RS27650	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KQY30_RS27660	COG0322	excinuclease ABC activity
KQY30_RS27665	COG1660	Displays ATPase and GTPase activities
KQY30_RS27670	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KQY30_RS27675	COG1481	regulation of sporulation
KQY30_RS27685	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KQY30_RS27690	COG0126	phosphoglycerate kinase activity
KQY30_RS27695	COG0149	triose-phosphate isomerase activity
KQY30_RS27700	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KQY30_RS27710	COG0166	Belongs to the GPI family
KQY30_RS27725	COG0363	glucosamine-6-phosphate deaminase activity
KQY30_RS27740	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KQY30_RS27750	COG0109	protoheme IX farnesyltransferase activity
KQY30_RS27775	COG1131	(ABC) transporter
KQY30_RS27800	COG0396	ATPase activity
KQY30_RS27805	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KQY30_RS27810	COG0822	iron-sulfur transferase activity
KQY30_RS27815	COG2151	metal-sulfur cluster biosynthetic enzyme
KQY30_RS27825	COG2076	Multidrug Resistance protein
KQY30_RS27830	COG3226	Transcriptional regulator
KQY30_RS27840	COG2171	N-acyltransferase activity
KQY30_RS27845	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KQY30_RS27870	COG1028	Short-chain dehydrogenase reductase Sdr
KQY30_RS27890	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KQY30_RS27895	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KQY30_RS27910	COG2252	PERMEase
KQY30_RS27920	COG0154	amidase activity
KQY30_RS27925	COG0768	penicillin binding
KQY30_RS27935	COG1414	Transcriptional regulator
KQY30_RS27985	COG0667	Aldo Keto reductase
KQY30_RS27990	COG1846	Transcriptional regulator
KQY30_RS27995	COG1902	pentaerythritol trinitrate reductase activity
KQY30_RS28005	COG1917	Cupin 2, conserved barrel domain protein
KQY30_RS28050	COG1797	cobyrinic acid a,c-diamide synthase activity
KQY30_RS28055	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
KQY30_RS28065	COG1492	cobalamin metabolic process
KQY30_RS28070	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
KQY30_RS28085	COG0235	Class ii aldolase
KQY30_RS28105	COG0488	(ABC) transporter
KQY30_RS28125	COG2837	iron assimilation
KQY30_RS28170	COG3387	PFAM Glycoside hydrolase 15-related
KQY30_RS28205	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KQY30_RS28210	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KQY30_RS28225	COG2261	transglycosylase associated protein
KQY30_RS28230	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KQY30_RS28255	COG1028	Short-chain dehydrogenase reductase Sdr
KQY30_RS28260	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KQY30_RS28270	COG2186	Transcriptional regulator
KQY30_RS28290	COG0560	Phosphoserine phosphatase
KQY30_RS28290	COG3830	Belongs to the UPF0237 family
KQY30_RS28310	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KQY30_RS28315	COG0300	oxidoreductase activity
KQY30_RS28320	COG4585	Histidine kinase
KQY30_RS28325	COG2197	response regulator
KQY30_RS28340	COG1119	ATPase activity
KQY30_RS28365	COG1881	PFAM PEBP family protein
KQY30_RS28375	COG2094	Belongs to the DNA glycosylase MPG family
KQY30_RS28405	COG0647	UMP catabolic process
KQY30_RS28410	COG1120	ATPase activity
KQY30_RS28430	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KQY30_RS28435	COG0497	DNA recombination
KQY30_RS28450	COG3387	PFAM Glycoside hydrolase 15-related
KQY30_RS28455	COG0504	CTP synthase activity
KQY30_RS28460	COG0494	nUDIX hydrolase
KQY30_RS28470	COG0686	Belongs to the AlaDH PNT family
KQY30_RS28485	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KQY30_RS28490	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KQY30_RS28495	COG1187	pseudouridine synthase activity
KQY30_RS28520	COG3541	Predicted nucleotidyltransferase
KQY30_RS28540	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KQY30_RS28550	COG1160	GTP binding
KQY30_RS28575	COG0671	phosphoesterase, PA-phosphatase related
KQY30_RS28580	COG0477	Major facilitator Superfamily
KQY30_RS28585	COG1960	acyl-CoA dehydrogenase activity
KQY30_RS28590	COG1799	cell septum assembly
KQY30_RS28610	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KQY30_RS28615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KQY30_RS28640	COG0641	radical SAM
KQY30_RS28670	COG0587	DNA-directed DNA polymerase activity
KQY30_RS28690	COG2890	protein-(glutamine-N5) methyltransferase activity
KQY30_RS28695	COG4565	transcriptional regulatory protein
KQY30_RS28725	COG1725	Transcriptional regulator
KQY30_RS28735	COG0726	polysaccharide deacetylase
KQY30_RS28745	COG0463	Glycosyl transferase, family 2
KQY30_RS28750	COG2755	lipolytic protein G-D-S-L family
KQY30_RS28765	COG2188	Transcriptional regulator
KQY30_RS28770	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
KQY30_RS28780	COG3842	ATPase activity
KQY30_RS28785	COG0697	spore germination
KQY30_RS28815	COG3876	Protein conserved in bacteria
KQY30_RS28830	COG1960	acyl-CoA dehydrogenase activity
KQY30_RS28860	COG2149	membrane
KQY30_RS28865	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
KQY30_RS28870	COG3573	Dehydrogenase
KQY30_RS28890	COG3265	gluconokinase activity
KQY30_RS28895	COG2186	Transcriptional regulator
KQY30_RS28920	COG1366	Belongs to the anti-sigma-factor antagonist family
KQY30_RS28945	COG0516	GMP reductase activity
KQY30_RS28945	COG0517	IMP dehydrogenase activity
KQY30_RS28950	COG0367	asparagine synthase
KQY30_RS29035	COG3903	Transcriptional regulator
KQY30_RS29035	COG3629	intracellular signal transduction
KQY30_RS29045	COG3903	Transcriptional regulator
KQY30_RS29045	COG3629	intracellular signal transduction
KQY30_RS29065	COG1733	regulation of RNA biosynthetic process
KQY30_RS29095	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KQY30_RS29095	COG0515	serine threonine protein kinase
KQY30_RS29100	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KQY30_RS29100	COG0515	serine threonine protein kinase
KQY30_RS29135	COG0596	Alpha beta hydrolase
KQY30_RS29140	COG1017	nitric oxide dioxygenase activity
KQY30_RS29140	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KQY30_RS29150	COG0583	DNA-binding transcription factor activity
KQY30_RS29170	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KQY30_RS29200	COG0667	Aldo Keto reductase
KQY30_RS29205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KQY30_RS29215	COG0598	Magnesium transport protein CorA
KQY30_RS29235	COG0215	cysteine-tRNA ligase activity
KQY30_RS29245	COG4948	Mandelate Racemase Muconate Lactonizing
KQY30_RS29250	COG1028	Short-chain dehydrogenase reductase Sdr
KQY30_RS29260	COG1129	ABC transporter
KQY30_RS29265	COG1172	Belongs to the binding-protein-dependent transport system permease family
KQY30_RS29270	COG2186	Transcriptional regulator
KQY30_RS29275	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KQY30_RS29280	COG0646	methionine synthase
KQY30_RS29280	COG1410	methionine synthase
KQY30_RS29290	COG4166	transmembrane transport
KQY30_RS29295	COG2197	response regulator
KQY30_RS29305	COG0517	IMP dehydrogenase activity
KQY30_RS29305	COG1994	Peptidase M50
KQY30_RS29325	COG1222	aaa ATPase
KQY30_RS29330	COG4122	O-methyltransferase activity
KQY30_RS29340	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
KQY30_RS29345	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
KQY30_RS29350	COG1609	Transcriptional regulator
KQY30_RS29360	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
KQY30_RS29395	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KQY30_RS29400	COG0805	protein transport
KQY30_RS29435	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KQY30_RS29440	COG0517	IMP dehydrogenase activity
KQY30_RS29440	COG4175	Glycine betaine
KQY30_RS29470	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KQY30_RS29485	COG0174	glutamine synthetase
KQY30_RS29490	COG1012	belongs to the aldehyde dehydrogenase family
KQY30_RS29535	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KQY30_RS29540	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KQY30_RS29545	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KQY30_RS29550	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KQY30_RS29555	COG5002	protein histidine kinase activity
KQY30_RS29560	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KQY30_RS29565	COG0072	phenylalanine-tRNA ligase activity
KQY30_RS29565	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KQY30_RS29595	COG1649	PFAM Uncharacterised BCR, COG1649
KQY30_RS29600	COG0697	spore germination
KQY30_RS29615	COG2205	protein histidine kinase activity
KQY30_RS29620	COG0745	RESPONSE REGULATOR receiver
KQY30_RS29630	COG0514	ATP-dependent DNA helicase (RecQ)
KQY30_RS29670	COG2197	response regulator
KQY30_RS29675	COG4941	Belongs to the sigma-70 factor family
KQY30_RS29685	COG2207	Transcriptional regulator
KQY30_RS29685	COG3708	Transcriptional regulator
KQY30_RS29690	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KQY30_RS29695	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KQY30_RS29700	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KQY30_RS29705	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KQY30_RS29710	COG1438	arginine binding
KQY30_RS29740	COG3189	MarR family transcriptional regulator
KQY30_RS29745	COG0137	argininosuccinate synthase activity
KQY30_RS29750	COG0165	Argininosuccinate lyase
KQY30_RS29760	COG0204	Acyl-transferase
KQY30_RS29760	COG0318	PFAM AMP-dependent synthetase and ligase
KQY30_RS29790	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KQY30_RS29795	COG2011	ABC-type metal ion transport system permease component
KQY30_RS29800	COG1464	Belongs to the NlpA lipoprotein family
KQY30_RS29820	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
KQY30_RS29825	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KQY30_RS29825	COG1648	precorrin-2 dehydrogenase activity
KQY30_RS29885	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KQY30_RS29945	COG2176	DNA-directed DNA polymerase activity
KQY30_RS29945	COG5002	protein histidine kinase activity
KQY30_RS29960	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KQY30_RS29965	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KQY30_RS29990	COG1560	Kdo2-lipid A biosynthetic process
KQY30_RS30005	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
KQY30_RS30010	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KQY30_RS30015	COG0217	transcriptional regulatory protein
KQY30_RS30020	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
KQY30_RS30025	COG0632	four-way junction helicase activity
KQY30_RS30040	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KQY30_RS30045	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KQY30_RS30050	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KQY30_RS30055	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KQY30_RS30060	COG1196	nuclear chromosome segregation
KQY30_RS30075	COG0124	histidyl-tRNA synthetase
KQY30_RS30095	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KQY30_RS30115	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KQY30_RS30120	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KQY30_RS30125	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KQY30_RS30130	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KQY30_RS30135	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KQY30_RS30140	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KQY30_RS30145	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KQY30_RS30150	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KQY30_RS30160	COG0006	proline dipeptidase activity
KQY30_RS30165	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KQY30_RS30170	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KQY30_RS30180	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KQY30_RS30185	COG0540	Belongs to the ATCase OTCase family
KQY30_RS30190	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KQY30_RS30200	COG0505	Belongs to the CarA family
KQY30_RS30205	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KQY30_RS30210	COG0167	dihydroorotate dehydrogenase activity
KQY30_RS30215	COG0284	orotidine-5'-phosphate decarboxylase activity
KQY30_RS30230	COG1758	RNA polymerase activity
KQY30_RS30240	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KQY30_RS30265	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KQY30_RS30275	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KQY30_RS30280	COG2390	Transcriptional regulator
KQY30_RS30290	COG1191	sigma factor activity
KQY30_RS30300	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KQY30_RS30315	COG0738	Major facilitator superfamily
KQY30_RS30320	COG1940	carbohydrate kinase activity
KQY30_RS30320	COG1846	Transcriptional regulator
KQY30_RS30335	COG3201	nicotinamide mononucleotide transporter
KQY30_RS30340	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KQY30_RS30340	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KQY30_RS30345	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KQY30_RS30350	COG0140	phosphoribosyl-ATP diphosphatase activity
KQY30_RS30355	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KQY30_RS30410	COG1960	acyl-CoA dehydrogenase activity
KQY30_RS30425	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KQY30_RS30430	COG1216	Glycosyl transferase, family 2
KQY30_RS30435	COG3030	protein affecting phage T7 exclusion by the F plasmid
KQY30_RS30445	COG2270	Major facilitator Superfamily
KQY30_RS30485	COG0438	transferase activity, transferring glycosyl groups
KQY30_RS30490	COG0438	transferase activity, transferring glycosyl groups
KQY30_RS30505	COG1984	allophanate hydrolase subunit 2
KQY30_RS30510	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KQY30_RS30515	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
KQY30_RS30520	COG2814	Major facilitator Superfamily
KQY30_RS30555	COG2018	Roadblock/LC7 domain
KQY30_RS30570	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KQY30_RS30575	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KQY30_RS30585	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
KQY30_RS30600	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KQY30_RS30610	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KQY30_RS30640	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KQY30_RS30680	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KQY30_RS30725	COG1695	Transcriptional regulator
KQY30_RS30740	COG5006	permease, DMT superfamily
KQY30_RS30760	COG0697	spore germination
KQY30_RS30820	COG2318	DinB family
KQY30_RS30840	COG0815	Transfers the fatty acyl group on membrane lipoproteins
KQY30_RS30870	COG1968	undecaprenyl-diphosphatase activity
KQY30_RS30915	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KQY30_RS30925	COG1024	Enoyl-CoA hydratase
KQY30_RS30930	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KQY30_RS30960	COG2124	cytochrome p450
KQY30_RS31005	COG1832	CoA-binding protein
KQY30_RS31030	COG1063	alcohol dehydrogenase
KQY30_RS31035	COG1739	Uncharacterized protein family UPF0029
KQY30_RS31040	COG0420	3'-5' exonuclease activity
KQY30_RS31045	COG0419	ATPase involved in DNA repair
KQY30_RS31050	COG1028	Short-chain dehydrogenase reductase Sdr
KQY30_RS31080	COG1595	DNA-templated transcription, initiation
KQY30_RS31085	COG2188	Transcriptional regulator
KQY30_RS31090	COG1940	carbohydrate kinase activity
KQY30_RS31095	COG0748	coenzyme F420 binding
KQY30_RS31105	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KQY30_RS31130	COG0456	acetyltransferase
KQY30_RS31145	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KQY30_RS31150	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KQY30_RS31155	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KQY30_RS31160	COG0156	8-amino-7-oxononanoate synthase activity
KQY30_RS31190	COG0740	serine-type endopeptidase activity
KQY30_RS31240	COG0596	Alpha beta hydrolase
KQY30_RS31255	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KQY30_RS31320	COG1484	DNA-dependent DNA replication
KQY30_RS31330	COG0539	negative regulation of cytoplasmic translation
KQY30_RS31345	COG4974	Belongs to the 'phage' integrase family
KQY30_RS31390	COG0515	serine threonine protein kinase
KQY30_RS31390	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KQY30_RS31455	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KQY30_RS31470	COG1073	alpha beta
KQY30_RS31525	COG4974	Belongs to the 'phage' integrase family
KQY30_RS31580	COG1309	transcriptional regulator
KQY30_RS31585	COG0831	urea catabolic process
KQY30_RS31590	COG0832	Belongs to the urease beta subunit family
KQY30_RS31595	COG0804	urea catabolic process
KQY30_RS31600	COG0830	nickel cation binding
KQY30_RS31605	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KQY30_RS31610	COG0829	nickel cation binding
KQY30_RS31625	COG2132	Multicopper oxidase
KQY30_RS31630	COG0028	Belongs to the TPP enzyme family
KQY30_RS31650	COG2268	Band 7 protein
KQY30_RS31675	COG0205	6-phosphofructokinase activity
KQY30_RS31680	COG3442	glutamine amidotransferase
KQY30_RS31700	COG1960	acyl-CoA dehydrogenase activity
KQY30_RS31705	COG0386	Belongs to the glutathione peroxidase family
KQY30_RS31710	COG1946	Acyl-CoA thioesterase
KQY30_RS31725	COG1132	(ABC) transporter
KQY30_RS31730	COG1132	(ABC) transporter
KQY30_RS31735	COG1846	Transcriptional regulator
KQY30_RS31740	COG1132	(ABC) transporter
KQY30_RS31750	COG0492	ferredoxin-NADP+ reductase activity
KQY30_RS31755	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KQY30_RS31765	COG1116	anion transmembrane transporter activity
KQY30_RS31770	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KQY30_RS31775	COG0432	Pfam Uncharacterised protein family UPF0047
KQY30_RS31785	COG0515	serine threonine protein kinase
KQY30_RS31835	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
KQY30_RS32035	COG1172	Belongs to the binding-protein-dependent transport system permease family
KQY30_RS32040	COG1129	ABC transporter
KQY30_RS32045	COG1846	Transcriptional regulator
KQY30_RS32045	COG1940	carbohydrate kinase activity
KQY30_RS32050	COG3250	beta-galactosidase activity
KQY30_RS32075	COG1028	Short-chain dehydrogenase reductase Sdr
KQY30_RS32085	COG0028	Belongs to the TPP enzyme family
KQY30_RS32090	COG2838	Isocitrate dehydrogenase
KQY30_RS32130	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KQY30_RS32135	COG2706	6-phosphogluconolactonase activity
KQY30_RS32150	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KQY30_RS32160	COG1902	pentaerythritol trinitrate reductase activity
KQY30_RS32165	COG0640	Transcriptional regulator
KQY30_RS32185	COG1309	transcriptional regulator
KQY30_RS32205	COG0671	phosphoesterase, PA-phosphatase related
KQY30_RS32225	COG1940	carbohydrate kinase activity
KQY30_RS32235	COG0673	inositol 2-dehydrogenase activity
KQY30_RS32245	COG4948	Mandelate Racemase Muconate Lactonizing
KQY30_RS32250	COG1414	Transcriptional regulator
KQY30_RS32265	COG0395	ABC-type sugar transport system, permease component
KQY30_RS32270	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KQY30_RS32280	COG0584	glycerophosphoryl diester phosphodiesterase
KQY30_RS32335	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KQY30_RS32365	COG1660	Displays ATPase and GTPase activities
KQY30_RS32370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KQY30_RS32380	COG0445	tRNA wobble uridine modification
KQY30_RS32395	COG4585	Histidine kinase
KQY30_RS32400	COG2197	response regulator
KQY30_RS32415	COG0738	Major facilitator superfamily
KQY30_RS32420	COG1940	carbohydrate kinase activity
KQY30_RS32445	COG0577	efflux transmembrane transporter activity
KQY30_RS32470	COG1349	DNA-binding transcription factor activity
KQY30_RS32480	COG0464	growth
KQY30_RS32510	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KQY30_RS32535	COG1028	Short-chain dehydrogenase reductase Sdr
KQY30_RS32565	COG2255	four-way junction helicase activity
KQY30_RS32585	COG1073	alpha beta
KQY30_RS32605	COG0789	Transcriptional regulator
KQY30_RS32620	COG1136	(ABC) transporter
KQY30_RS32625	COG1136	(ABC) transporter
KQY30_RS32635	COG0642	Histidine kinase
KQY30_RS32640	COG0745	RESPONSE REGULATOR receiver
KQY30_RS32645	COG0745	RESPONSE REGULATOR receiver
KQY30_RS32650	COG2205	protein histidine kinase activity
KQY30_RS32665	COG2239	Acts as a magnesium transporter
KQY30_RS32755	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KQY30_RS32760	COG0028	Belongs to the TPP enzyme family
KQY30_RS32765	COG0318	PFAM AMP-dependent synthetase and ligase
KQY30_RS32770	COG0583	DNA-binding transcription factor activity
KQY30_RS32810	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KQY30_RS32825	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KQY30_RS32830	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KQY30_RS32835	COG3485	protocatechuate 3,4-dioxygenase
KQY30_RS32840	COG3485	protocatechuate 3,4-dioxygenase
KQY30_RS32860	COG1414	Transcriptional regulator
KQY30_RS32975	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KQY30_RS32980	COG1846	Transcriptional regulator
KQY30_RS33025	COG0501	Belongs to the peptidase M48B family
KQY30_RS33030	COG2197	response regulator
KQY30_RS33035	COG1132	(ABC) transporter
KQY30_RS33040	COG1132	(ABC) transporter
KQY30_RS33050	COG0515	serine threonine protein kinase
KQY30_RS33055	COG5297	Belongs to the glycosyl hydrolase family 6
KQY30_RS33065	COG5297	Belongs to the glycosyl hydrolase family 6
KQY30_RS33065	COG4733	cellulase activity
KQY30_RS33120	COG1316	TRANSCRIPTIONal
KQY30_RS33165	COG0456	acetyltransferase
KQY30_RS33175	COG0671	phosphoesterase, PA-phosphatase related
KQY30_RS33180	COG0586	Pfam SNARE associated Golgi protein
KQY30_RS33200	COG3594	Acyltransferase
KQY30_RS33215	COG0412	Dienelactone hydrolase
KQY30_RS33245	COG0477	Major facilitator Superfamily
KQY30_RS33270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KQY30_RS33270	COG2022	thiamine diphosphate biosynthetic process
KQY30_RS33275	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KQY30_RS33305	COG1028	Short-chain dehydrogenase reductase Sdr
KQY30_RS33330	COG0475	glutathione-regulated potassium exporter activity
KQY30_RS33355	COG1461	Dihydroxyacetone kinase
KQY30_RS33365	COG0537	adenosine 5'-monophosphoramidase activity
KQY30_RS33370	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KQY30_RS33380	COG0442	prolyl-tRNA aminoacylation
KQY30_RS33385	COG0438	transferase activity, transferring glycosyl groups
KQY30_RS33410	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
KQY30_RS33420	COG0709	Synthesizes selenophosphate from selenide and ATP
KQY30_RS33425	COG1960	acyl-CoA dehydrogenase activity
KQY30_RS33430	COG1309	transcriptional regulator
KQY30_RS33435	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KQY30_RS33445	COG1309	transcriptional regulator
KQY30_RS33450	COG4191	Histidine kinase
KQY30_RS33465	COG0656	L-ascorbic acid biosynthetic process
KQY30_RS33475	COG1309	transcriptional regulator
KQY30_RS33480	COG2197	response regulator
KQY30_RS33485	COG4585	Histidine kinase
KQY30_RS33540	COG1522	sequence-specific DNA binding
KQY30_RS33545	COG1309	transcriptional regulator
KQY30_RS33565	COG0604	alcohol dehydrogenase
KQY30_RS33575	COG0583	DNA-binding transcription factor activity
KQY30_RS33685	COG0596	Alpha beta hydrolase
KQY30_RS33720	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KQY30_RS33720	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KQY30_RS33755	COG0288	reversible hydration of carbon dioxide
KQY30_RS33765	COG0789	Transcriptional regulator
KQY30_RS33785	COG3336	cytochrome c oxidase
KQY30_RS33790	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KQY30_RS33795	COG0475	glutathione-regulated potassium exporter activity
KQY30_RS33810	COG4106	trans-aconitate 2-methyltransferase activity
KQY30_RS33815	COG0640	Transcriptional regulator
KQY30_RS33830	COG0604	alcohol dehydrogenase
KQY30_RS33830	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KQY30_RS33830	COG3321	synthase
KQY30_RS33830	COG4221	oxidoreductase activity
KQY30_RS33835	COG1028	Short-chain dehydrogenase reductase Sdr
KQY30_RS33865	COG1309	transcriptional regulator
KQY30_RS33890	COG1028	Short-chain dehydrogenase reductase Sdr
KQY30_RS33900	COG0367	asparagine synthase
KQY30_RS33910	COG1028	Short-chain dehydrogenase reductase Sdr
KQY30_RS33940	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KQY30_RS33950	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
KQY30_RS33955	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
KQY30_RS33980	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
KQY30_RS33985	COG1819	glycosyl
KQY30_RS34005	COG2207	Transcriptional regulator
KQY30_RS34020	COG1028	Short-chain dehydrogenase reductase Sdr
KQY30_RS34030	COG4326	sporulation control protein
KQY30_RS34070	COG1028	Short-chain dehydrogenase reductase Sdr
KQY30_RS34080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KQY30_RS34095	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KQY30_RS34100	COG3938	Belongs to the proline racemase family
KQY30_RS34125	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KQY30_RS34130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KQY30_RS34135	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KQY30_RS34160	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KQY30_RS34175	COG0546	phosphoglycolate phosphatase activity
KQY30_RS34180	COG1796	DNA polymerase
KQY30_RS34180	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KQY30_RS34195	COG3383	formate dehydrogenase (NAD+) activity
KQY30_RS34195	COG0243	molybdopterin cofactor binding
KQY30_RS34200	COG0437	4 iron, 4 sulfur cluster binding
KQY30_RS34230	COG2813	Specifically methylates the guanine in position
KQY30_RS34235	COG3585	molybdate ion transport
KQY30_RS34275	COG1793	dna ligase
KQY30_RS34285	COG0515	serine threonine protein kinase
KQY30_RS34295	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KQY30_RS34300	COG0387	Pfam Sodium calcium exchanger
KQY30_RS34355	COG2356	endonuclease I
KQY30_RS34365	COG3469	chitinase activity
KQY30_RS34410	COG0515	serine threonine protein kinase
KQY30_RS34430	COG0277	FAD linked oxidase domain protein
KQY30_RS34465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KQY30_RS34470	COG0765	amino acid transport
KQY30_RS34520	COG3387	PFAM Glycoside hydrolase 15-related
KQY30_RS34535	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KQY30_RS34550	COG1132	(ABC) transporter
KQY30_RS34555	COG2755	lipolytic protein G-D-S-L family
KQY30_RS34565	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KQY30_RS34590	COG3321	synthase
KQY30_RS34590	COG0604	alcohol dehydrogenase
KQY30_RS34615	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KQY30_RS34635	COG0604	alcohol dehydrogenase
KQY30_RS34635	COG3321	synthase
KQY30_RS34670	COG4326	sporulation control protein
KQY30_RS34705	COG1196	nuclear chromosome segregation
KQY30_RS34705	COG0739	heme binding
KQY30_RS34705	COG0741	lytic transglycosylase activity
KQY30_RS34715	COG0745	RESPONSE REGULATOR receiver
KQY30_RS34720	COG2205	protein histidine kinase activity
KQY30_RS34725	COG1486	melibiose metabolic process
KQY30_RS34745	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KQY30_RS34750	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
KQY30_RS34805	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KQY30_RS34825	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KQY30_RS34835	COG2376	Dihydroxyacetone kinase
KQY30_RS34855	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KQY30_RS34875	COG1175	transmembrane transport
KQY30_RS34880	COG0395	ABC-type sugar transport system, permease component
KQY30_RS34885	COG4948	Mandelate Racemase Muconate Lactonizing
KQY30_RS34925	COG2197	response regulator
KQY30_RS34970	COG4221	oxidoreductase activity
KQY30_RS34980	COG1309	transcriptional regulator
KQY30_RS34985	COG4221	oxidoreductase activity
KQY30_RS34995	COG1028	Short-chain dehydrogenase reductase Sdr
KQY30_RS35005	COG1309	transcriptional regulator
KQY30_RS35010	COG0596	Alpha beta hydrolase
KQY30_RS35080	COG2755	lipolytic protein G-D-S-L family
KQY30_RS35170	COG3903	Transcriptional regulator
KQY30_RS35170	COG3629	intracellular signal transduction
KQY30_RS35190	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KQY30_RS35210	COG1309	transcriptional regulator
KQY30_RS35215	COG0702	epimerase
KQY30_RS35230	COG4221	oxidoreductase activity
KQY30_RS35265	COG2197	response regulator
KQY30_RS35305	COG1028	Short-chain dehydrogenase reductase Sdr
KQY30_RS35330	COG1609	Transcriptional regulator
KQY30_RS35350	COG1175	transmembrane transport
KQY30_RS35355	COG0395	ABC-type sugar transport system, permease component
KQY30_RS35360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KQY30_RS35370	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KQY30_RS35370	COG2755	lipolytic protein G-D-S-L family
KQY30_RS35425	COG2814	Major facilitator Superfamily
KQY30_RS35440	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KQY30_RS35525	COG1522	sequence-specific DNA binding
KQY30_RS35615	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KQY30_RS35640	COG1132	(ABC) transporter
KQY30_RS35710	COG1028	Short-chain dehydrogenase reductase Sdr
KQY30_RS35735	COG0346	lactoylglutathione lyase activity
KQY30_RS35745	COG1733	regulation of RNA biosynthetic process
KQY30_RS35760	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KQY30_RS35775	COG1028	Short-chain dehydrogenase reductase Sdr
KQY30_RS35780	COG1309	transcriptional regulator
KQY30_RS35805	COG1309	transcriptional regulator
KQY30_RS36120	COG1175	transmembrane transport
KQY30_RS36125	COG1175	transmembrane transport
KQY30_RS36170	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KQY30_RS36290	COG1196	nuclear chromosome segregation
KQY30_RS36305	COG0640	Transcriptional regulator
KQY30_RS36380	COG1012	belongs to the aldehyde dehydrogenase family
KQY30_RS36415	COG3973	AAA domain
KQY30_RS36425	COG0300	oxidoreductase activity
KQY30_RS36425	COG0318	PFAM AMP-dependent synthetase and ligase
KQY30_RS36425	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KQY30_RS36425	COG1028	Short-chain dehydrogenase reductase Sdr
KQY30_RS36425	COG3321	synthase
KQY30_RS36425	COG0300	oxidoreductase activity
KQY30_RS36425	COG0318	PFAM AMP-dependent synthetase and ligase
KQY30_RS36425	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KQY30_RS36425	COG1028	Short-chain dehydrogenase reductase Sdr
KQY30_RS36425	COG3321	synthase
KQY30_RS36745	COG0330	HflC and HflK could