locus-tag	class	description
GR129_RS00020	COG0483	inositol monophosphate 1-phosphatase activity
GR129_RS00035	COG2124	cytochrome p450
GR129_RS00040	COG1024	Enoyl-CoA hydratase
GR129_RS00045	COG1119	ATPase activity
GR129_RS00060	COG0784	Response regulator, receiver
GR129_RS00070	COG4251	negative regulation of phosphorylation
GR129_RS00105	COG2084	Dehydrogenase
GR129_RS00135	COG1028	Short-chain dehydrogenase reductase Sdr
GR129_RS00140	COG0656	L-ascorbic acid biosynthetic process
GR129_RS00165	COG0477	Major facilitator Superfamily
GR129_RS00185	COG0318	PFAM AMP-dependent synthetase and ligase
GR129_RS00230	COG1309	transcriptional regulator
GR129_RS00255	COG0367	asparagine synthase
GR129_RS00315	COG4716	Myosin-crossreactive antigen
GR129_RS00320	COG1309	transcriptional regulator
GR129_RS00420	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GR129_RS00430	COG0673	inositol 2-dehydrogenase activity
GR129_RS00440	COG2211	Major facilitator Superfamily
GR129_RS00480	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GR129_RS00500	COG1733	regulation of RNA biosynthetic process
GR129_RS00510	COG1959	2 iron, 2 sulfur cluster binding
GR129_RS00515	COG1028	Short-chain dehydrogenase reductase Sdr
GR129_RS00535	COG0318	PFAM AMP-dependent synthetase and ligase
GR129_RS00570	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GR129_RS00580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GR129_RS00625	COG2205	protein histidine kinase activity
GR129_RS00685	COG2197	response regulator
GR129_RS00700	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
GR129_RS00705	COG1228	amidohydrolase
GR129_RS00710	COG1278	Cold shock
GR129_RS00790	COG0367	asparagine synthase
GR129_RS00805	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GR129_RS00810	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GR129_RS00865	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GR129_RS00870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GR129_RS00895	COG1349	DNA-binding transcription factor activity
GR129_RS00920	COG1595	DNA-templated transcription, initiation
GR129_RS00935	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GR129_RS00940	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GR129_RS00985	COG0596	Alpha beta hydrolase
GR129_RS01010	COG1609	Transcriptional regulator
GR129_RS01020	COG1175	transmembrane transport
GR129_RS01060	COG1309	transcriptional regulator
GR129_RS01065	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GR129_RS01105	COG2124	cytochrome p450
GR129_RS01180	COG2814	Major facilitator Superfamily
GR129_RS01190	COG3251	PFAM MbtH domain protein
GR129_RS01210	COG2124	cytochrome p450
GR129_RS01220	COG0366	Alpha amylase catalytic
GR129_RS01230	COG1175	transmembrane transport
GR129_RS01250	COG1309	transcriptional regulator
GR129_RS01255	COG0277	FAD linked oxidase domain protein
GR129_RS01260	COG1733	regulation of RNA biosynthetic process
GR129_RS01280	COG0477	Major facilitator Superfamily
GR129_RS01310	COG3631	Ketosteroid isomerase-related protein
GR129_RS01315	COG0702	epimerase
GR129_RS01360	COG3046	protein related to deoxyribodipyrimidine photolyase
GR129_RS01375	COG1120	ATPase activity
GR129_RS01380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GR129_RS01410	COG1535	isochorismatase
GR129_RS01410	COG3433	isochorismatase activity
GR129_RS01415	COG0318	PFAM AMP-dependent synthetase and ligase
GR129_RS01460	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
GR129_RS01520	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
GR129_RS01540	COG1309	transcriptional regulator
GR129_RS01580	COG1028	Short-chain dehydrogenase reductase Sdr
GR129_RS01595	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GR129_RS01610	COG1278	Cold shock
GR129_RS01625	COG0069	glutamate synthase activity
GR129_RS01640	COG4977	sequence-specific DNA binding
GR129_RS01660	COG1609	Transcriptional regulator
GR129_RS01670	COG1172	Belongs to the binding-protein-dependent transport system permease family
GR129_RS01690	COG1609	Transcriptional regulator
GR129_RS01700	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GR129_RS01740	COG3896	Chloramphenicol phosphotransferase-like protein
GR129_RS01770	COG4948	Mandelate Racemase Muconate Lactonizing
GR129_RS01775	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GR129_RS01780	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GR129_RS01845	COG0110	maltose O-acetyltransferase activity
GR129_RS01885	COG0477	Major facilitator Superfamily
GR129_RS01925	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GR129_RS01945	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GR129_RS01960	COG0604	alcohol dehydrogenase
GR129_RS01980	COG1703	isobutyryl-CoA mutase activity
GR129_RS01980	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GR129_RS01980	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GR129_RS01985	COG2132	Multicopper oxidase
GR129_RS01995	COG0367	asparagine synthase
GR129_RS02065	COG0456	acetyltransferase
GR129_RS02085	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GR129_RS02125	COG1396	sequence-specific DNA binding
GR129_RS02155	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GR129_RS02160	COG0542	response to heat
GR129_RS02180	COG1597	lipid kinase activity
GR129_RS02185	COG0277	FAD linked oxidase domain protein
GR129_RS02215	COG1132	(ABC) transporter
GR129_RS02230	COG3979	chitinase
GR129_RS02260	COG2755	lipolytic protein G-D-S-L family
GR129_RS02280	COG0726	polysaccharide deacetylase
GR129_RS02290	COG2837	iron assimilation
GR129_RS02320	COG1228	amidohydrolase
GR129_RS02330	COG0589	response to stress
GR129_RS02360	COG0583	DNA-binding transcription factor activity
GR129_RS02400	COG1584	GPR1 FUN34 yaaH family protein
GR129_RS02425	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GR129_RS02430	COG2755	lipolytic protein G-D-S-L family
GR129_RS02445	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GR129_RS02465	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GR129_RS02470	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GR129_RS02475	COG2080	2 iron, 2 sulfur cluster binding
GR129_RS02495	COG0768	penicillin binding
GR129_RS02505	COG5002	protein histidine kinase activity
GR129_RS02510	COG0745	RESPONSE REGULATOR receiver
GR129_RS02545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GR129_RS02555	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GR129_RS02575	COG2409	Drug exporters of the RND superfamily
GR129_RS02580	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GR129_RS02590	COG1090	epimerase
GR129_RS02605	COG1316	TRANSCRIPTIONal
GR129_RS02610	COG0640	Transcriptional regulator
GR129_RS02685	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
GR129_RS02700	COG0516	GMP reductase activity
GR129_RS02700	COG0517	IMP dehydrogenase activity
GR129_RS02715	COG0517	IMP dehydrogenase activity
GR129_RS02720	COG0589	response to stress
GR129_RS02735	COG0701	Predicted permease
GR129_RS02770	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
GR129_RS02795	COG0375	protein maturation
GR129_RS02810	COG0298	carbon dioxide binding
GR129_RS02815	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
GR129_RS02825	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GR129_RS02835	COG1285	pathogenesis
GR129_RS02885	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GR129_RS02890	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GR129_RS02900	COG0438	transferase activity, transferring glycosyl groups
GR129_RS02940	COG0667	Aldo Keto reductase
GR129_RS02955	COG1846	Transcriptional regulator
GR129_RS02970	COG0437	4 iron, 4 sulfur cluster binding
GR129_RS02980	COG3383	formate dehydrogenase (NAD+) activity
GR129_RS02980	COG0243	molybdopterin cofactor binding
GR129_RS02985	COG0243	molybdopterin cofactor binding
GR129_RS02985	COG3383	formate dehydrogenase (NAD+) activity
GR129_RS02990	COG0709	Synthesizes selenophosphate from selenide and ATP
GR129_RS03005	COG1921	L-seryl-tRNASec selenium transferase activity
GR129_RS03080	COG0673	inositol 2-dehydrogenase activity
GR129_RS03085	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
GR129_RS03090	COG1335	isochorismatase
GR129_RS03120	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GR129_RS03135	COG0009	L-threonylcarbamoyladenylate synthase
GR129_RS03175	COG0656	L-ascorbic acid biosynthetic process
GR129_RS03190	COG2208	phosphoserine phosphatase activity
GR129_RS03215	COG1793	dna ligase
GR129_RS03220	COG0181	hydroxymethylbilane synthase activity
GR129_RS03230	COG0842	Transport permease protein
GR129_RS03270	COG0366	Alpha amylase catalytic
GR129_RS03280	COG3281	Trehalose synthase
GR129_RS03285	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GR129_RS03290	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
GR129_RS03305	COG1252	NADH dehydrogenase
GR129_RS03360	COG5002	protein histidine kinase activity
GR129_RS03380	COG3189	MarR family transcriptional regulator
GR129_RS03400	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GR129_RS03415	COG3852	Histidine kinase
GR129_RS03445	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GR129_RS03450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GR129_RS03470	COG0667	Aldo Keto reductase
GR129_RS03475	COG0328	RNA-DNA hybrid ribonuclease activity
GR129_RS03495	COG1191	sigma factor activity
GR129_RS03520	COG0667	Aldo Keto reductase
GR129_RS03525	COG0583	DNA-binding transcription factor activity
GR129_RS03535	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GR129_RS03560	COG0531	amino acid
GR129_RS03565	COG3250	beta-galactosidase activity
GR129_RS03610	COG0367	asparagine synthase
GR129_RS03635	COG3511	phospholipase C
GR129_RS03655	COG0510	thiamine kinase activity
GR129_RS03695	COG1024	Enoyl-CoA hydratase
GR129_RS03725	COG2070	2-Nitropropane dioxygenase
GR129_RS03745	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GR129_RS03755	COG4989	oxidoreductase activity
GR129_RS03765	COG1028	Short-chain dehydrogenase reductase Sdr
GR129_RS03775	COG1960	acyl-CoA dehydrogenase activity
GR129_RS03800	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
GR129_RS03800	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GR129_RS03805	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GR129_RS03810	COG0297	glycogen (starch) synthase activity
GR129_RS03815	COG0438	transferase activity, transferring glycosyl groups
GR129_RS03840	COG2192	nodulation
GR129_RS03845	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GR129_RS03855	COG1674	ftsk spoiiie
GR129_RS03880	COG0464	growth
GR129_RS03920	COG2376	Dihydroxyacetone kinase
GR129_RS03925	COG1461	Dihydroxyacetone kinase
GR129_RS03940	COG5297	Belongs to the glycosyl hydrolase family 6
GR129_RS03940	COG4733	cellulase activity
GR129_RS03955	COG1902	pentaerythritol trinitrate reductase activity
GR129_RS03955	COG0446	pyridine nucleotide-disulphide oxidoreductase
GR129_RS03980	COG2890	protein-(glutamine-N5) methyltransferase activity
GR129_RS03995	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GR129_RS04030	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GR129_RS04040	COG5650	phosphatidylinositol metabolic process
GR129_RS04050	COG2066	Belongs to the glutaminase family
GR129_RS04070	COG1968	undecaprenyl-diphosphatase activity
GR129_RS04075	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GR129_RS04080	COG1993	acr, cog1993
GR129_RS04085	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GR129_RS04120	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GR129_RS04135	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GR129_RS04155	COG2197	response regulator
GR129_RS04160	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GR129_RS04170	COG3469	chitinase activity
GR129_RS04205	COG0589	response to stress
GR129_RS04210	COG4191	Histidine kinase
GR129_RS04215	COG0549	Belongs to the carbamate kinase family
GR129_RS04220	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GR129_RS04230	COG0531	amino acid
GR129_RS04245	COG1028	Short-chain dehydrogenase reductase Sdr
GR129_RS04270	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GR129_RS04275	COG0463	Glycosyl transferase, family 2
GR129_RS04315	COG1349	DNA-binding transcription factor activity
GR129_RS04365	COG1940	carbohydrate kinase activity
GR129_RS04370	COG3145	DNA-N1-methyladenine dioxygenase activity
GR129_RS04385	COG2813	Specifically methylates the guanine in position
GR129_RS04390	COG0191	fructose-bisphosphate aldolase activity
GR129_RS04400	COG1349	DNA-binding transcription factor activity
GR129_RS04410	COG1595	DNA-templated transcription, initiation
GR129_RS04435	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GR129_RS04450	COG0180	Tryptophanyl-tRNA synthetase
GR129_RS04475	COG0445	tRNA wobble uridine modification
GR129_RS04480	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GR129_RS04490	COG1660	Displays ATPase and GTPase activities
GR129_RS04520	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GR129_RS04600	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GR129_RS04620	COG1309	transcriptional regulator
GR129_RS04635	COG0640	Transcriptional regulator
GR129_RS04640	COG1902	pentaerythritol trinitrate reductase activity
GR129_RS04655	COG1960	acyl-CoA dehydrogenase activity
GR129_RS04665	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GR129_RS04695	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GR129_RS04700	COG0477	Major facilitator Superfamily
GR129_RS04725	COG0714	Associated with various cellular activities
GR129_RS04740	COG1472	Belongs to the glycosyl hydrolase 3 family
GR129_RS04750	COG0492	ferredoxin-NADP+ reductase activity
GR129_RS04760	COG1132	(ABC) transporter
GR129_RS04795	COG1132	(ABC) transporter
GR129_RS04805	COG0254	rRNA binding
GR129_RS04820	COG1946	Acyl-CoA thioesterase
GR129_RS04830	COG2018	Roadblock/LC7 domain
GR129_RS04880	COG1940	carbohydrate kinase activity
GR129_RS04880	COG1846	Transcriptional regulator
GR129_RS04905	COG1012	belongs to the aldehyde dehydrogenase family
GR129_RS04925	COG4221	oxidoreductase activity
GR129_RS04960	COG0714	Associated with various cellular activities
GR129_RS05030	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GR129_RS05035	COG0443	Heat shock 70 kDa protein
GR129_RS05045	COG3959	Transketolase, thiamine diphosphate binding domain
GR129_RS05105	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GR129_RS05115	COG2197	response regulator
GR129_RS05130	COG0464	growth
GR129_RS05205	COG0586	Pfam SNARE associated Golgi protein
GR129_RS05240	COG1960	acyl-CoA dehydrogenase activity
GR129_RS05245	COG1960	acyl-CoA dehydrogenase activity
GR129_RS05260	COG1793	dna ligase
GR129_RS05280	COG3424	synthase
GR129_RS05285	COG2124	cytochrome p450
GR129_RS05295	COG1960	acyl-CoA dehydrogenase activity
GR129_RS05305	COG0242	peptide deformylase activity
GR129_RS05315	COG3442	glutamine amidotransferase
GR129_RS05320	COG0205	6-phosphofructokinase activity
GR129_RS05335	COG1522	sequence-specific DNA binding
GR129_RS05340	COG1834	amidinotransferase
GR129_RS05345	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GR129_RS05355	COG0204	Acyl-transferase
GR129_RS05360	COG0829	nickel cation binding
GR129_RS05365	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GR129_RS05375	COG0804	urea catabolic process
GR129_RS05380	COG0832	Belongs to the urease beta subunit family
GR129_RS05385	COG0831	urea catabolic process
GR129_RS05395	COG0740	serine-type endopeptidase activity
GR129_RS05430	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GR129_RS05440	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GR129_RS05500	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GR129_RS05505	COG3663	DNA glycosylase
GR129_RS05515	COG1940	carbohydrate kinase activity
GR129_RS05525	COG2188	Transcriptional regulator
GR129_RS05530	COG1595	DNA-templated transcription, initiation
GR129_RS05540	COG2267	carboxylic ester hydrolase activity
GR129_RS05555	COG0626	cystathionine gamma-synthase activity
GR129_RS05590	COG0419	ATPase involved in DNA repair
GR129_RS05600	COG1739	Uncharacterized protein family UPF0029
GR129_RS05615	COG1832	CoA-binding protein
GR129_RS05620	COG0531	amino acid
GR129_RS05625	COG0640	Transcriptional regulator
GR129_RS05650	COG0110	maltose O-acetyltransferase activity
GR129_RS05675	COG1819	glycosyl
GR129_RS05680	COG0596	Alpha beta hydrolase
GR129_RS05715	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GR129_RS05735	COG1733	regulation of RNA biosynthetic process
GR129_RS05755	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GR129_RS05760	COG0673	inositol 2-dehydrogenase activity
GR129_RS05775	COG2318	DinB family
GR129_RS05790	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GR129_RS05795	COG0747	negative chemotaxis
GR129_RS05800	COG1028	Short-chain dehydrogenase reductase Sdr
GR129_RS05835	COG0697	spore germination
GR129_RS05880	COG0509	glycine decarboxylation via glycine cleavage system
GR129_RS05955	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GR129_RS05955	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GR129_RS05965	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GR129_RS05985	COG1716	ATPase activity
GR129_RS06005	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GR129_RS06035	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GR129_RS06045	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GR129_RS06090	COG2018	Roadblock/LC7 domain
GR129_RS06105	COG1414	Transcriptional regulator
GR129_RS06135	COG4336	lyase activity
GR129_RS06140	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GR129_RS06145	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GR129_RS06150	COG1984	allophanate hydrolase subunit 2
GR129_RS06155	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GR129_RS06170	COG0438	transferase activity, transferring glycosyl groups
GR129_RS06205	COG2364	Membrane
GR129_RS06215	COG2270	Major facilitator Superfamily
GR129_RS06230	COG1216	Glycosyl transferase, family 2
GR129_RS06255	COG1960	acyl-CoA dehydrogenase activity
GR129_RS06310	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GR129_RS06315	COG0140	phosphoribosyl-ATP diphosphatase activity
GR129_RS06320	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GR129_RS06325	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GR129_RS06325	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GR129_RS06330	COG3201	nicotinamide mononucleotide transporter
GR129_RS06340	COG1846	Transcriptional regulator
GR129_RS06340	COG1940	carbohydrate kinase activity
GR129_RS06345	COG0738	Major facilitator superfamily
GR129_RS06355	COG2233	PERMEase
GR129_RS06365	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GR129_RS06375	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GR129_RS06400	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GR129_RS06405	COG3842	ATPase activity
GR129_RS06425	COG2188	Transcriptional regulator
GR129_RS06435	COG0531	amino acid
GR129_RS06465	COG2390	Transcriptional regulator
GR129_RS06470	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GR129_RS06535	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GR129_RS06555	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GR129_RS06570	COG0194	GDP metabolic process
GR129_RS06580	COG0284	orotidine-5'-phosphate decarboxylase activity
GR129_RS06585	COG0167	dihydroorotate dehydrogenase activity
GR129_RS06590	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GR129_RS06595	COG0505	Belongs to the CarA family
GR129_RS06605	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GR129_RS06615	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GR129_RS06625	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GR129_RS06630	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GR129_RS06635	COG0006	proline dipeptidase activity
GR129_RS06645	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GR129_RS06650	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GR129_RS06655	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GR129_RS06660	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GR129_RS06665	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GR129_RS06670	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GR129_RS06675	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GR129_RS06695	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GR129_RS06710	COG0124	histidyl-tRNA synthetase
GR129_RS06720	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GR129_RS06725	COG1196	nuclear chromosome segregation
GR129_RS06730	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GR129_RS06740	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GR129_RS06745	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GR129_RS06750	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GR129_RS06765	COG0632	four-way junction helicase activity
GR129_RS06770	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GR129_RS06775	COG0217	transcriptional regulatory protein
GR129_RS06780	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
GR129_RS06785	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
GR129_RS06795	COG0438	transferase activity, transferring glycosyl groups
GR129_RS06800	COG1560	Kdo2-lipid A biosynthetic process
GR129_RS06825	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GR129_RS06840	COG5002	protein histidine kinase activity
GR129_RS06840	COG2176	DNA-directed DNA polymerase activity
GR129_RS06895	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GR129_RS06945	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GR129_RS06945	COG1648	precorrin-2 dehydrogenase activity
GR129_RS06965	COG1464	Belongs to the NlpA lipoprotein family
GR129_RS06970	COG2011	ABC-type metal ion transport system permease component
GR129_RS06975	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GR129_RS06980	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GR129_RS07010	COG2132	Multicopper oxidase
GR129_RS07015	COG0477	Major facilitator Superfamily
GR129_RS07030	COG0165	Argininosuccinate lyase
GR129_RS07035	COG0137	argininosuccinate synthase activity
GR129_RS07060	COG1132	(ABC) transporter
GR129_RS07075	COG1438	arginine binding
GR129_RS07080	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GR129_RS07085	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GR129_RS07090	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GR129_RS07095	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GR129_RS07120	COG0463	Glycosyl transferase, family 2
GR129_RS07150	COG1649	PFAM Uncharacterised BCR, COG1649
GR129_RS07180	COG0072	phenylalanine-tRNA ligase activity
GR129_RS07180	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GR129_RS07185	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GR129_RS07190	COG5002	protein histidine kinase activity
GR129_RS07195	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GR129_RS07200	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GR129_RS07205	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GR129_RS07210	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GR129_RS07250	COG1012	belongs to the aldehyde dehydrogenase family
GR129_RS07265	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GR129_RS07280	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GR129_RS07290	COG4176	ABC-type proline glycine betaine transport system permease component
GR129_RS07295	COG0517	IMP dehydrogenase activity
GR129_RS07295	COG4175	Glycine betaine
GR129_RS07300	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GR129_RS07355	COG0805	protein transport
GR129_RS07360	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GR129_RS07380	COG2378	regulation of single-species biofilm formation
GR129_RS07390	COG0545	Peptidyl-prolyl cis-trans isomerase
GR129_RS07395	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
GR129_RS07405	COG1609	Transcriptional regulator
GR129_RS07410	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
GR129_RS07430	COG4122	O-methyltransferase activity
GR129_RS07435	COG1222	aaa ATPase
GR129_RS07460	COG1994	Peptidase M50
GR129_RS07460	COG0517	IMP dehydrogenase activity
GR129_RS07470	COG2197	response regulator
GR129_RS07475	COG0747	negative chemotaxis
GR129_RS07485	COG0646	methionine synthase
GR129_RS07485	COG1410	methionine synthase
GR129_RS07490	COG1414	Transcriptional regulator
GR129_RS07495	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GR129_RS07500	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GR129_RS07505	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GR129_RS07515	COG0215	cysteine-tRNA ligase activity
GR129_RS07535	COG0598	Magnesium transport protein CorA
GR129_RS07540	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GR129_RS07545	COG0667	Aldo Keto reductase
GR129_RS07585	COG2345	Transcriptional regulator
GR129_RS07590	COG2867	negative regulation of translational initiation
GR129_RS07590	COG2226	methyltransferase
GR129_RS07595	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GR129_RS07600	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GR129_RS07605	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GR129_RS07610	COG0662	Cupin 2, conserved barrel domain protein
GR129_RS07620	COG2329	Antibiotic biosynthesis monooxygenase
GR129_RS07625	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GR129_RS07630	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
GR129_RS07635	COG0477	Major facilitator Superfamily
GR129_RS07640	COG1309	transcriptional regulator
GR129_RS07645	COG2890	protein-(glutamine-N5) methyltransferase activity
GR129_RS07650	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GR129_RS07650	COG1796	DNA polymerase
GR129_RS07665	COG3012	SEC-C Motif Domain Protein
GR129_RS07670	COG2186	Transcriptional regulator
GR129_RS07675	COG3265	gluconokinase activity
GR129_RS07705	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GR129_RS07715	COG1960	acyl-CoA dehydrogenase activity
GR129_RS07735	COG3876	Protein conserved in bacteria
GR129_RS07785	COG1960	acyl-CoA dehydrogenase activity
GR129_RS07815	COG1309	transcriptional regulator
GR129_RS07825	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
GR129_RS07850	COG2755	lipolytic protein G-D-S-L family
GR129_RS07870	COG0726	polysaccharide deacetylase
GR129_RS07870	COG1649	PFAM Uncharacterised BCR, COG1649
GR129_RS07895	COG1725	Transcriptional regulator
GR129_RS07930	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GR129_RS07930	COG0662	Cupin 2, conserved barrel domain protein
GR129_RS07940	COG0587	DNA-directed DNA polymerase activity
GR129_RS07965	COG1126	abc transporter atp-binding protein
GR129_RS07975	COG0765	amino acid transport
GR129_RS07980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GR129_RS07990	COG1799	cell septum assembly
GR129_RS07995	COG1960	acyl-CoA dehydrogenase activity
GR129_RS08000	COG0477	Major facilitator Superfamily
GR129_RS08010	COG0671	phosphoesterase, PA-phosphatase related
GR129_RS08025	COG1652	LysM domain
GR129_RS08040	COG1160	GTP binding
GR129_RS08050	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GR129_RS08075	COG3541	Predicted nucleotidyltransferase
GR129_RS08085	COG1187	pseudouridine synthase activity
GR129_RS08090	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GR129_RS08095	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GR129_RS08110	COG0686	Belongs to the AlaDH PNT family
GR129_RS08125	COG0504	CTP synthase activity
GR129_RS08130	COG3387	PFAM Glycoside hydrolase 15-related
GR129_RS08145	COG0438	transferase activity, transferring glycosyl groups
GR129_RS08155	COG0497	DNA recombination
GR129_RS08160	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GR129_RS08180	COG1120	ATPase activity
GR129_RS08185	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GR129_RS08190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GR129_RS08195	COG0647	UMP catabolic process
GR129_RS08230	COG2094	Belongs to the DNA glycosylase MPG family
GR129_RS08240	COG1881	PFAM PEBP family protein
GR129_RS08260	COG1119	ATPase activity
GR129_RS08275	COG2197	response regulator
GR129_RS08285	COG1028	Short-chain dehydrogenase reductase Sdr
GR129_RS08290	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GR129_RS08300	COG0842	Transport permease protein
GR129_RS08300	COG1131	(ABC) transporter
GR129_RS08300	COG1716	ATPase activity
GR129_RS08305	COG3830	Belongs to the UPF0237 family
GR129_RS08305	COG0560	Phosphoserine phosphatase
GR129_RS08325	COG2186	Transcriptional regulator
GR129_RS08350	COG2207	Transcriptional regulator
GR129_RS08355	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GR129_RS08365	COG2223	nitrite transmembrane transporter activity
GR129_RS08370	COG0154	amidase activity
GR129_RS08380	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GR129_RS08400	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GR129_RS08405	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GR129_RS08415	COG1404	Belongs to the peptidase S8 family
GR129_RS08420	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GR129_RS08430	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GR129_RS08475	COG1302	Protein conserved in bacteria
GR129_RS08485	COG1024	Enoyl-CoA hydratase
GR129_RS08515	COG0235	Class ii aldolase
GR129_RS08535	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
GR129_RS08540	COG1492	cobalamin metabolic process
GR129_RS08560	COG1797	cobyrinic acid a,c-diamide synthase activity
GR129_RS08595	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
GR129_RS08630	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GR129_RS08640	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GR129_RS08645	COG1917	Cupin 2, conserved barrel domain protein
GR129_RS08650	COG5285	phytanoyl-CoA dioxygenase
GR129_RS08670	COG1414	Transcriptional regulator
GR129_RS08695	COG1349	DNA-binding transcription factor activity
GR129_RS08705	COG1175	transmembrane transport
GR129_RS08710	COG0395	ABC-type sugar transport system, permease component
GR129_RS08755	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GR129_RS08765	COG2171	N-acyltransferase activity
GR129_RS08770	COG3226	Transcriptional regulator
GR129_RS08785	COG0822	iron-sulfur transferase activity
GR129_RS08790	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GR129_RS08795	COG0396	ATPase activity
GR129_RS08825	COG1131	(ABC) transporter
GR129_RS08835	COG1612	heme a metabolic process
GR129_RS08845	COG0109	protoheme IX farnesyltransferase activity
GR129_RS08855	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GR129_RS08870	COG0363	glucosamine-6-phosphate deaminase activity
GR129_RS08880	COG0166	Belongs to the GPI family
GR129_RS08895	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GR129_RS08900	COG0149	triose-phosphate isomerase activity
GR129_RS08905	COG0126	phosphoglycerate kinase activity
GR129_RS08910	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GR129_RS08915	COG1481	regulation of sporulation
GR129_RS08920	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GR129_RS08925	COG1660	Displays ATPase and GTPase activities
GR129_RS08930	COG0322	excinuclease ABC activity
GR129_RS08945	COG1609	Transcriptional regulator
GR129_RS08965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GR129_RS08970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GR129_RS08975	COG0765	amino acid transport
GR129_RS08985	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GR129_RS08990	COG0477	Major facilitator Superfamily
GR129_RS08995	COG0387	Pfam Sodium calcium exchanger
GR129_RS09000	COG0861	Integral membrane protein TerC family
GR129_RS09015	COG0556	nucleotide-excision repair
GR129_RS09025	COG0584	glycerophosphoryl diester phosphodiesterase
GR129_RS09030	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GR129_RS09035	COG2313	pseudouridylate synthase activity
GR129_RS09045	COG2226	methyltransferase
GR129_RS09050	COG0598	Magnesium transport protein CorA
GR129_RS09135	COG0237	dephospho-CoA kinase activity
GR129_RS09150	COG0539	negative regulation of cytoplasmic translation
GR129_RS09155	COG2226	methyltransferase
GR129_RS09160	COG1643	Atp-dependent helicase
GR129_RS09195	COG2050	protein possibly involved in aromatic compounds catabolism
GR129_RS09200	COG0683	leucine binding
GR129_RS09205	COG0559	Belongs to the binding-protein-dependent transport system permease family
GR129_RS09215	COG0411	ABC transporter
GR129_RS09220	COG0410	ABC transporter
GR129_RS09265	COG1605	Chorismate mutase
GR129_RS09265	COG0287	Prephenate dehydrogenase
GR129_RS09285	COG1028	Short-chain dehydrogenase reductase Sdr
GR129_RS09290	COG1028	Short-chain dehydrogenase reductase Sdr
GR129_RS09295	COG1024	Enoyl-CoA hydratase
GR129_RS09325	COG1028	Short-chain dehydrogenase reductase Sdr
GR129_RS09330	COG1960	acyl-CoA dehydrogenase activity
GR129_RS09335	COG1960	acyl-CoA dehydrogenase activity
GR129_RS09355	COG0069	glutamate synthase activity
GR129_RS09355	COG0070	glutamate synthase
GR129_RS09355	COG0067	glutamate synthase
GR129_RS09365	COG1397	ADP-ribosylglycohydrolase
GR129_RS09385	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GR129_RS09390	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GR129_RS09400	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GR129_RS09410	COG0159	tryptophan synthase activity
GR129_RS09415	COG0133	tryptophan synthase activity
GR129_RS09425	COG0134	indole-3-glycerol-phosphate synthase activity
GR129_RS09450	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GR129_RS09460	COG0346	lactoylglutathione lyase activity
GR129_RS09475	COG0107	imidazoleglycerol-phosphate synthase activity
GR129_RS09480	COG0251	oxidation-reduction process
GR129_RS09485	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GR129_RS09490	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GR129_RS09495	COG0131	Imidazoleglycerol-phosphate dehydratase
GR129_RS09500	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GR129_RS09505	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GR129_RS09525	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GR129_RS09545	COG1432	Conserved Protein
GR129_RS09550	COG0587	DNA-directed DNA polymerase activity
GR129_RS09595	COG2153	protein acetylation
GR129_RS09605	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GR129_RS09610	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GR129_RS09615	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GR129_RS09630	COG1799	cell septum assembly
GR129_RS09645	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GR129_RS09650	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GR129_RS09655	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GR129_RS09665	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GR129_RS09670	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GR129_RS09680	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GR129_RS09695	COG0275	rRNA processing
GR129_RS09705	COG0714	Associated with various cellular activities
GR129_RS09735	COG1132	(ABC) transporter
GR129_RS09740	COG1511	domain protein
GR129_RS09745	COG1309	transcriptional regulator
GR129_RS09770	COG0352	thiamine-phosphate diphosphorylase activity
GR129_RS09790	COG2022	thiamine diphosphate biosynthetic process
GR129_RS09790	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GR129_RS09800	COG2022	thiamine diphosphate biosynthetic process
GR129_RS09805	COG2815	serine threonine protein kinase
GR129_RS09805	COG0515	serine threonine protein kinase
GR129_RS09810	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GR129_RS09815	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GR129_RS09820	COG2193	ferroxidase activity
GR129_RS09845	COG0205	6-phosphofructokinase activity
GR129_RS09850	COG2197	response regulator
GR129_RS09855	COG4585	Histidine kinase
GR129_RS09880	COG1940	carbohydrate kinase activity
GR129_RS09890	COG0003	Pfam Anion-transporting ATPase
GR129_RS09910	COG0438	transferase activity, transferring glycosyl groups
GR129_RS09925	COG0791	NLP P60 protein
GR129_RS09925	COG3883	PFAM NLP P60 protein
GR129_RS09955	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GR129_RS09960	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GR129_RS09965	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GR129_RS09970	COG0723	plastoquinol--plastocyanin reductase activity
GR129_RS09975	COG2010	Cytochrome c
GR129_RS09980	COG1845	cytochrome c oxidase, subunit III
GR129_RS10000	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GR129_RS10005	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GR129_RS10045	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GR129_RS10050	COG4585	Histidine kinase
GR129_RS10055	COG2197	response regulator
GR129_RS10060	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GR129_RS10090	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GR129_RS10110	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GR129_RS10130	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GR129_RS10140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GR129_RS10145	COG0508	dehydrogenase complex catalyzes the overall conversion of
GR129_RS10155	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GR129_RS10195	COG0321	lipoyl(octanoyl) transferase activity
GR129_RS10200	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GR129_RS10220	COG0174	glutamine synthetase
GR129_RS10240	COG0501	Belongs to the peptidase M48B family
GR129_RS10270	COG0745	RESPONSE REGULATOR receiver
GR129_RS10285	COG2197	response regulator
GR129_RS10325	COG0366	Alpha amylase catalytic
GR129_RS10330	COG3833	ABC-type maltose transport systems, permease component
GR129_RS10335	COG1175	transmembrane transport
GR129_RS10345	COG1609	Transcriptional regulator
GR129_RS10355	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GR129_RS10370	COG0174	glutamine synthetase
GR129_RS10375	COG1017	nitric oxide dioxygenase activity
GR129_RS10375	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GR129_RS10380	COG1959	2 iron, 2 sulfur cluster binding
GR129_RS10465	COG2814	Major facilitator Superfamily
GR129_RS10480	COG0477	Major facilitator Superfamily
GR129_RS10485	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GR129_RS10515	COG1994	Peptidase M50
GR129_RS10570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GR129_RS10575	COG1120	ATPase activity
GR129_RS10585	COG2837	iron assimilation
GR129_RS10590	COG0672	)-iron permease
GR129_RS10610	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GR129_RS10615	COG2814	Major facilitator Superfamily
GR129_RS10635	COG2259	Doxx family
GR129_RS10725	COG3022	response to hydroperoxide
GR129_RS10730	COG0800	Aldolase
GR129_RS10735	COG0328	RNA-DNA hybrid ribonuclease activity
GR129_RS10735	COG0406	alpha-ribazole phosphatase activity
GR129_RS10745	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GR129_RS10755	COG1028	Short-chain dehydrogenase reductase Sdr
GR129_RS10770	COG1131	(ABC) transporter
GR129_RS10780	COG4585	Histidine kinase
GR129_RS10785	COG2197	response regulator
GR129_RS10795	COG0477	Major facilitator Superfamily
GR129_RS10825	COG0860	N-Acetylmuramoyl-L-alanine amidase
GR129_RS10835	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GR129_RS10860	COG1309	transcriptional regulator
GR129_RS10915	COG3845	ABC transporter
GR129_RS10925	COG0741	lytic transglycosylase activity
GR129_RS10930	COG3619	membrane
GR129_RS10935	COG2124	cytochrome p450
GR129_RS10940	COG0183	Belongs to the thiolase family
GR129_RS10950	COG0477	Major facilitator Superfamily
GR129_RS10975	COG0583	DNA-binding transcription factor activity
GR129_RS11015	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GR129_RS11045	COG3973	AAA domain
GR129_RS11085	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GR129_RS11100	COG1358	cellular component organization or biogenesis
GR129_RS11145	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GR129_RS11155	COG1309	transcriptional regulator
GR129_RS11170	COG0667	Aldo Keto reductase
GR129_RS11175	COG0789	Transcriptional regulator
GR129_RS11190	COG1741	Belongs to the pirin family
GR129_RS11205	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GR129_RS11210	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GR129_RS11215	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GR129_RS11245	COG1335	isochorismatase
GR129_RS11250	COG1335	isochorismatase
GR129_RS11270	COG2130	NADP-dependent
GR129_RS11325	COG0477	Major facilitator Superfamily
GR129_RS11370	COG0318	PFAM AMP-dependent synthetase and ligase
GR129_RS11375	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GR129_RS11375	COG0825	malonyl-CoA metabolic process
GR129_RS11380	COG1404	Belongs to the peptidase S8 family
GR129_RS11405	COG1077	Cell shape determining protein MreB Mrl
GR129_RS11480	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GR129_RS11485	COG0358	DNA primase activity
GR129_RS11495	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GR129_RS11500	COG2949	membrane
GR129_RS11525	COG0395	ABC-type sugar transport system, permease component
GR129_RS11530	COG1175	transmembrane transport
GR129_RS11540	COG0535	radical SAM domain protein
GR129_RS11570	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GR129_RS11570	COG0574	Belongs to the PEP-utilizing enzyme family
GR129_RS11575	COG1846	Transcriptional regulator
GR129_RS11575	COG1940	carbohydrate kinase activity
GR129_RS11615	COG0477	Major facilitator Superfamily
GR129_RS11630	COG0667	Aldo Keto reductase
GR129_RS11640	COG0423	glycine-tRNA ligase activity
GR129_RS11650	COG1121	(ABC) transporter
GR129_RS11655	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GR129_RS11665	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GR129_RS11670	COG1381	Involved in DNA repair and RecF pathway recombination
GR129_RS11685	COG1396	sequence-specific DNA binding
GR129_RS11690	COG0747	negative chemotaxis
GR129_RS11700	COG0444	Belongs to the ABC transporter superfamily
GR129_RS11705	COG4608	Belongs to the ABC transporter superfamily
GR129_RS11710	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GR129_RS11715	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GR129_RS11735	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GR129_RS11770	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GR129_RS11805	COG1619	proteins homologs of microcin C7 resistance protein MccF
GR129_RS11810	COG2315	Protein conserved in bacteria
GR129_RS11820	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GR129_RS11835	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GR129_RS11840	COG1234	tRNA 3'-trailer cleavage
GR129_RS11845	COG0537	adenosine 5'-monophosphoramidase activity
GR129_RS11880	COG0484	heat shock protein binding
GR129_RS11885	COG1420	regulation of RNA biosynthetic process
GR129_RS11920	COG0481	GTPase activity
GR129_RS11930	COG0268	Binds directly to 16S ribosomal RNA
GR129_RS11945	COG2353	YceI-like domain
GR129_RS11960	COG1555	photosystem II stabilization
GR129_RS11965	COG1307	EDD domain protein, DegV family
GR129_RS11975	COG0495	leucyl-tRNA aminoacylation
GR129_RS11995	COG0588	phosphoglycerate mutase activity
GR129_RS12000	COG0799	negative regulation of ribosome biogenesis
GR129_RS12010	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GR129_RS12015	COG0501	Belongs to the peptidase M48B family
GR129_RS12030	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GR129_RS12040	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GR129_RS12045	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GR129_RS12050	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GR129_RS12060	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GR129_RS12065	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GR129_RS12080	COG1530	ribonuclease E activity
GR129_RS12095	COG0672	)-iron permease
GR129_RS12105	COG2837	iron assimilation
GR129_RS12120	COG0772	Belongs to the SEDS family
GR129_RS12125	COG0768	penicillin binding
GR129_RS12140	COG1077	Cell shape determining protein MreB Mrl
GR129_RS12145	COG0105	UTP biosynthetic process
GR129_RS12155	COG0285	dihydrofolate synthase activity
GR129_RS12160	COG0525	valine-tRNA ligase activity
GR129_RS12170	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GR129_RS12180	COG0740	serine-type endopeptidase activity
GR129_RS12185	COG0544	peptidyl-prolyl cis-trans isomerase activity
GR129_RS12220	COG3594	Acyltransferase
GR129_RS12240	COG0698	ribose 5-phosphate isomerase
GR129_RS12245	COG1113	amino acid transport
GR129_RS12255	COG1940	carbohydrate kinase activity
GR129_RS12265	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GR129_RS12270	COG1116	anion transmembrane transporter activity
GR129_RS12285	COG1113	amino acid transport
GR129_RS12295	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GR129_RS12305	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GR129_RS12365	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GR129_RS12395	COG0668	transmembrane transport
GR129_RS12415	COG1175	transmembrane transport
GR129_RS12420	COG0395	ABC-type sugar transport system, permease component
GR129_RS12425	COG1486	melibiose metabolic process
GR129_RS12440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GR129_RS12470	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GR129_RS12520	COG0629	single-stranded DNA binding
GR129_RS12540	COG3903	Transcriptional regulator
GR129_RS12540	COG3629	intracellular signal transduction
GR129_RS12565	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GR129_RS12590	COG4555	ABC transporter
GR129_RS12615	COG0318	PFAM AMP-dependent synthetase and ligase
GR129_RS12630	COG0110	maltose O-acetyltransferase activity
GR129_RS12650	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GR129_RS12665	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GR129_RS12675	COG2304	oxidoreductase activity
GR129_RS12740	COG1131	(ABC) transporter
GR129_RS12760	COG3718	enzyme involved in inositol metabolism
GR129_RS12770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GR129_RS12805	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GR129_RS12825	COG1129	ABC transporter
GR129_RS12830	COG1879	ABC-type sugar transport system periplasmic component
GR129_RS12835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GR129_RS12840	COG1869	D-ribose catabolic process
GR129_RS12860	COG1028	Short-chain dehydrogenase reductase Sdr
GR129_RS12875	COG0673	inositol 2-dehydrogenase activity
GR129_RS12880	COG1609	Transcriptional regulator
GR129_RS12930	COG0028	Belongs to the TPP enzyme family
GR129_RS12955	COG1946	Acyl-CoA thioesterase
GR129_RS12970	COG1309	transcriptional regulator
GR129_RS12975	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GR129_RS12990	COG1960	acyl-CoA dehydrogenase activity
GR129_RS13010	COG3486	L-lysine 6-monooxygenase (NADPH) activity
GR129_RS13035	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GR129_RS13045	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GR129_RS13050	COG4977	sequence-specific DNA binding
GR129_RS13060	COG0589	response to stress
GR129_RS13110	COG3979	chitinase
GR129_RS13120	COG0745	RESPONSE REGULATOR receiver
GR129_RS13145	COG0406	alpha-ribazole phosphatase activity
GR129_RS13195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GR129_RS13205	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GR129_RS13220	COG3397	chitin binding
GR129_RS13240	COG2186	Transcriptional regulator
GR129_RS13280	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GR129_RS13290	COG2188	Transcriptional regulator
GR129_RS13315	COG0673	inositol 2-dehydrogenase activity
GR129_RS13320	COG4702	Belongs to the UPF0303 family
GR129_RS13340	COG0706	membrane insertase activity
GR129_RS13350	COG1733	regulation of RNA biosynthetic process
GR129_RS13360	COG3764	Sortase (surface protein transpeptidase)
GR129_RS13400	COG0071	Belongs to the small heat shock protein (HSP20) family
GR129_RS13415	COG2733	membrane
GR129_RS13425	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GR129_RS13460	COG2076	Multidrug Resistance protein
GR129_RS13465	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GR129_RS13480	COG1131	(ABC) transporter
GR129_RS13495	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GR129_RS13500	COG1263	PTS System
GR129_RS13500	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GR129_RS13505	COG1263	PTS System
GR129_RS13505	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GR129_RS13510	COG1263	PTS System
GR129_RS13510	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GR129_RS13550	COG1113	amino acid transport
GR129_RS13565	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GR129_RS13575	COG1335	isochorismatase
GR129_RS13585	COG4412	M6 family metalloprotease domain protein
GR129_RS13585	COG3291	Pkd domain containing protein
GR129_RS13610	COG0277	FAD linked oxidase domain protein
GR129_RS13620	COG3185	4-Hydroxyphenylpyruvate dioxygenase
GR129_RS13685	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GR129_RS13695	COG1678	Uncharacterized ACR, COG1678
GR129_RS13700	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GR129_RS13705	COG0776	regulation of translation
GR129_RS13715	COG3973	AAA domain
GR129_RS13725	COG2264	protein methyltransferase activity
GR129_RS13735	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GR129_RS13740	COG0793	Belongs to the peptidase S41A family
GR129_RS13745	COG2177	Part of the ABC transporter FtsEX involved in
GR129_RS13750	COG2884	Cell division ATP-binding protein ftsE
GR129_RS13765	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GR129_RS13770	COG0515	serine threonine protein kinase
GR129_RS13775	COG0515	serine threonine protein kinase
GR129_RS13785	COG1653	transport
GR129_RS13790	COG1175	transmembrane transport
GR129_RS13795	COG0395	ABC-type sugar transport system, permease component
GR129_RS13825	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GR129_RS13830	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GR129_RS13835	COG1764	response to oxidative stress
GR129_RS13840	COG1846	Transcriptional regulator
GR129_RS13855	COG1215	transferase activity, transferring glycosyl groups
GR129_RS13880	COG1134	teichoic acid transport
GR129_RS13885	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GR129_RS13890	COG1215	transferase activity, transferring glycosyl groups
GR129_RS13900	COG2902	Dehydrogenase
GR129_RS13925	COG0653	protein targeting
GR129_RS13935	COG3214	Protein conserved in bacteria
GR129_RS13940	COG2197	response regulator
GR129_RS13945	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GR129_RS13955	COG0823	Involved in the tonB-independent uptake of proteins
GR129_RS13960	COG5002	protein histidine kinase activity
GR129_RS13960	COG5000	phosphorelay sensor kinase activity
GR129_RS13965	COG0745	RESPONSE REGULATOR receiver
GR129_RS13970	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
GR129_RS13990	COG0714	Associated with various cellular activities
GR129_RS14030	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GR129_RS14040	COG1482	cell wall glycoprotein biosynthetic process
GR129_RS14050	COG2835	tetraacyldisaccharide 4'-kinase activity
GR129_RS14105	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
GR129_RS14105	COG0778	Nitroreductase
GR129_RS14125	COG1316	TRANSCRIPTIONal
GR129_RS14130	COG1316	TRANSCRIPTIONal
GR129_RS14135	COG1316	TRANSCRIPTIONal
GR129_RS14155	COG1316	TRANSCRIPTIONal
GR129_RS14170	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GR129_RS14195	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GR129_RS14210	COG2205	protein histidine kinase activity
GR129_RS14215	COG0745	RESPONSE REGULATOR receiver
GR129_RS14250	COG1366	Belongs to the anti-sigma-factor antagonist family
GR129_RS14255	COG1191	sigma factor activity
GR129_RS14260	COG1228	amidohydrolase
GR129_RS14270	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GR129_RS14275	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GR129_RS14320	COG0789	Transcriptional regulator
GR129_RS14335	COG0318	PFAM AMP-dependent synthetase and ligase
GR129_RS14340	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GR129_RS14345	COG0519	Catalyzes the synthesis of GMP from XMP
GR129_RS14345	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GR129_RS14350	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GR129_RS14360	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GR129_RS14375	COG1960	acyl-CoA dehydrogenase activity
GR129_RS14380	COG1960	acyl-CoA dehydrogenase activity
GR129_RS14385	COG0745	RESPONSE REGULATOR receiver
GR129_RS14415	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GR129_RS14420	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GR129_RS14475	COG0183	Belongs to the thiolase family
GR129_RS14505	COG0577	efflux transmembrane transporter activity
GR129_RS14505	COG1136	(ABC) transporter
GR129_RS14510	COG0577	efflux transmembrane transporter activity
GR129_RS14515	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GR129_RS14520	COG1252	NADH dehydrogenase
GR129_RS14550	COG1652	LysM domain
GR129_RS14560	COG2124	cytochrome p450
GR129_RS14620	COG1136	(ABC) transporter
GR129_RS14620	COG0577	efflux transmembrane transporter activity
GR129_RS14670	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GR129_RS14675	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GR129_RS14680	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GR129_RS14685	COG0193	aminoacyl-tRNA hydrolase activity
GR129_RS14695	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GR129_RS14705	COG1309	transcriptional regulator
GR129_RS14725	COG4106	trans-aconitate 2-methyltransferase activity
GR129_RS14730	COG1846	Transcriptional regulator
GR129_RS14735	COG2197	response regulator
GR129_RS14745	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GR129_RS14785	COG0488	(ABC) transporter
GR129_RS14795	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GR129_RS14800	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GR129_RS14805	COG1388	LysM domain
GR129_RS14810	COG0084	hydrolase, TatD family'
GR129_RS14865	COG0310	cobalt ion transport
GR129_RS14875	COG1122	ATPase activity
GR129_RS14925	COG2409	Drug exporters of the RND superfamily
GR129_RS14935	COG0793	Belongs to the peptidase S41A family
GR129_RS14935	COG4946	Tricorn protease homolog
GR129_RS14945	COG1028	Short-chain dehydrogenase reductase Sdr
GR129_RS14955	COG2072	flavoprotein involved in K transport
GR129_RS14965	COG0708	Exodeoxyribonuclease III
GR129_RS14985	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GR129_RS14990	COG0521	Mo-molybdopterin cofactor biosynthetic process
GR129_RS14990	COG0315	cyclic pyranopterin monophosphate synthase activity
GR129_RS14995	COG0315	cyclic pyranopterin monophosphate synthase activity
GR129_RS15010	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GR129_RS15025	COG0477	Major facilitator Superfamily
GR129_RS15035	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GR129_RS15060	COG3191	aminopeptidase activity
GR129_RS15065	COG1376	ErfK ybiS ycfS ynhG family protein
GR129_RS15105	COG3384	dioxygenase
GR129_RS15110	COG1846	Transcriptional regulator
GR129_RS15140	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GR129_RS15150	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GR129_RS15165	COG1309	transcriptional regulator
GR129_RS15230	COG0386	Belongs to the glutathione peroxidase family
GR129_RS15255	COG1686	Belongs to the peptidase S11 family
GR129_RS15300	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
GR129_RS15330	COG1028	Short-chain dehydrogenase reductase Sdr
GR129_RS15345	COG3903	Transcriptional regulator
GR129_RS15345	COG3629	intracellular signal transduction
GR129_RS15355	COG1396	sequence-specific DNA binding
GR129_RS15360	COG0318	PFAM AMP-dependent synthetase and ligase
GR129_RS15375	COG1024	Enoyl-CoA hydratase
GR129_RS15380	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GR129_RS15380	COG0515	serine threonine protein kinase
GR129_RS15395	COG1309	transcriptional regulator
GR129_RS15400	COG1522	sequence-specific DNA binding
GR129_RS15405	COG1280	lysine exporter protein (LysE YggA)
GR129_RS15415	COG1960	acyl-CoA dehydrogenase activity
GR129_RS15440	COG2072	flavoprotein involved in K transport
GR129_RS15445	COG1181	Belongs to the D-alanine--D-alanine ligase family
GR129_RS15450	COG1024	Enoyl-CoA hydratase
GR129_RS15480	COG1960	acyl-CoA dehydrogenase activity
GR129_RS15485	COG1028	Short-chain dehydrogenase reductase Sdr
GR129_RS15500	COG1960	acyl-CoA dehydrogenase activity
GR129_RS15505	COG1960	acyl-CoA dehydrogenase activity
GR129_RS15605	COG4821	SIS domain
GR129_RS15615	COG0259	pyridoxamine-phosphate oxidase activity
GR129_RS15635	COG1024	Enoyl-CoA hydratase
GR129_RS15640	COG0318	PFAM AMP-dependent synthetase and ligase
GR129_RS15655	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GR129_RS15680	COG5006	permease, DMT superfamily
GR129_RS15690	COG0277	FAD linked oxidase domain protein
GR129_RS15690	COG0247	lactate metabolic process
GR129_RS15695	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GR129_RS15735	COG0667	Aldo Keto reductase
GR129_RS15775	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GR129_RS15800	COG2814	Major facilitator Superfamily
GR129_RS15810	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GR129_RS15815	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
GR129_RS15820	COG1278	Cold shock
GR129_RS15855	COG1061	Type III restriction enzyme res subunit
GR129_RS15870	COG3973	AAA domain
GR129_RS15880	COG2268	Band 7 protein
GR129_RS15920	COG1737	Transcriptional regulator
GR129_RS15925	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GR129_RS15930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GR129_RS15930	COG1263	PTS System
GR129_RS15935	COG4106	trans-aconitate 2-methyltransferase activity
GR129_RS15950	COG0459	protein refolding
GR129_RS15965	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GR129_RS15970	COG0463	Glycosyl transferase, family 2
GR129_RS15990	COG1653	transport
GR129_RS16005	COG1105	Belongs to the carbohydrate kinase PfkB family
GR129_RS16015	COG3300	MHYT domain
GR129_RS16015	COG5001	Diguanylate cyclase
GR129_RS16030	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GR129_RS16065	COG0723	plastoquinol--plastocyanin reductase activity
GR129_RS16065	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GR129_RS16090	COG2867	negative regulation of translational initiation
GR129_RS16095	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GR129_RS16100	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GR129_RS16115	COG2329	Antibiotic biosynthesis monooxygenase
GR129_RS16120	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GR129_RS16130	COG3842	ATPase activity
GR129_RS16140	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GR129_RS16150	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GR129_RS16155	COG0215	cysteine-tRNA ligase activity
GR129_RS16185	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GR129_RS16190	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GR129_RS16195	COG1329	Transcriptional regulator
GR129_RS16215	COG5002	protein histidine kinase activity
GR129_RS16230	COG0640	Transcriptional regulator
GR129_RS16235	COG0798	PFAM Bile acid sodium symporter
GR129_RS16250	COG2188	Transcriptional regulator
GR129_RS16285	COG0588	phosphoglycerate mutase activity
GR129_RS16315	COG0438	transferase activity, transferring glycosyl groups
GR129_RS16325	COG0791	NLP P60 protein
GR129_RS16325	COG3883	PFAM NLP P60 protein
GR129_RS16330	COG2204	response regulator
GR129_RS16370	COG0613	PHP domain protein
GR129_RS16400	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GR129_RS16410	COG1309	transcriptional regulator
GR129_RS16420	COG0546	phosphoglycolate phosphatase activity
GR129_RS16425	COG2186	Transcriptional regulator
GR129_RS16435	COG1609	Transcriptional regulator
GR129_RS16440	COG4552	Acetyltransferase involved in intracellular survival and related
GR129_RS16450	COG1490	D-aminoacyl-tRNA deacylase activity
GR129_RS16455	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GR129_RS16465	COG3485	protocatechuate 3,4-dioxygenase
GR129_RS16480	COG2897	thiosulfate sulfurtransferase activity
GR129_RS16515	COG0745	RESPONSE REGULATOR receiver
GR129_RS16520	COG1609	Transcriptional regulator
GR129_RS16525	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GR129_RS16535	COG0745	RESPONSE REGULATOR receiver
GR129_RS16545	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GR129_RS16550	COG0456	acetyltransferase
GR129_RS16555	COG1725	Transcriptional regulator
GR129_RS16570	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GR129_RS16610	COG0306	phosphate transporter
GR129_RS16620	COG1937	Protein conserved in bacteria
GR129_RS16645	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GR129_RS16665	COG0277	FAD linked oxidase domain protein
GR129_RS16670	COG0671	phosphoesterase, PA-phosphatase related
GR129_RS16675	COG0791	NLP P60 protein
GR129_RS16685	COG1028	Short-chain dehydrogenase reductase Sdr
GR129_RS16690	COG1028	Short-chain dehydrogenase reductase Sdr
GR129_RS16775	COG1252	NADH dehydrogenase
GR129_RS16805	COG0579	oxidoreductase
GR129_RS16810	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GR129_RS16835	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GR129_RS16835	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GR129_RS16870	COG0513	Belongs to the DEAD box helicase family
GR129_RS16915	COG1643	Atp-dependent helicase
GR129_RS16945	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GR129_RS16965	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GR129_RS16970	COG0047	phosphoribosylformylglycinamidine synthase activity
GR129_RS16975	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GR129_RS17010	COG2197	response regulator
GR129_RS17020	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GR129_RS17035	COG0151	Belongs to the GarS family
GR129_RS17060	COG1028	Short-chain dehydrogenase reductase Sdr
GR129_RS17090	COG0433	COG0433 Predicted ATPase
GR129_RS17105	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GR129_RS17140	COG1191	sigma factor activity
GR129_RS17145	COG1191	sigma factor activity
GR129_RS17160	COG1846	Transcriptional regulator
GR129_RS17180	COG3467	pyridoxamine 5'-phosphate
GR129_RS17195	COG0463	Glycosyl transferase, family 2
GR129_RS17200	COG2205	protein histidine kinase activity
GR129_RS17205	COG0745	RESPONSE REGULATOR receiver
GR129_RS17260	COG0318	PFAM AMP-dependent synthetase and ligase
GR129_RS17265	COG1595	DNA-templated transcription, initiation
GR129_RS17310	COG0653	protein targeting
GR129_RS17355	COG1999	signal sequence binding
GR129_RS17370	COG2837	iron assimilation
GR129_RS17380	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GR129_RS17385	COG0561	phosphatase activity
GR129_RS17405	COG1131	(ABC) transporter
GR129_RS17420	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
GR129_RS17455	COG0561	phosphatase activity
GR129_RS17460	COG4988	ABC transporter
GR129_RS17465	COG1294	oxidase, subunit
GR129_RS17470	COG1271	oxidase subunit
GR129_RS17475	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GR129_RS17485	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GR129_RS17495	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GR129_RS17510	COG1414	Transcriptional regulator
GR129_RS17520	COG0662	Cupin 2, conserved barrel domain protein
GR129_RS17525	COG1950	PFAM Membrane protein of
GR129_RS17530	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GR129_RS17535	COG0626	cystathionine gamma-synthase activity
GR129_RS17560	COG2814	Major facilitator Superfamily
GR129_RS17595	COG0305	Participates in initiation and elongation during chromosome replication
GR129_RS17605	COG0359	binds to the 23S rRNA
GR129_RS17610	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GR129_RS17615	COG0629	single-stranded DNA binding
GR129_RS17620	COG0360	Binds together with S18 to 16S ribosomal RNA
GR129_RS17645	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GR129_RS17665	COG0617	tRNA 3'-terminal CCA addition
GR129_RS17680	COG2815	serine threonine protein kinase
GR129_RS17680	COG0515	serine threonine protein kinase
GR129_RS17685	COG1595	DNA-templated transcription, initiation
GR129_RS17695	COG0492	ferredoxin-NADP+ reductase activity
GR129_RS17700	COG3118	belongs to the thioredoxin family
GR129_RS17715	COG1192	Involved in chromosome partitioning
GR129_RS17720	COG0357	Ribosomal RNA small subunit methyltransferase G
GR129_RS17730	COG0706	membrane insertase activity
GR129_RS17735	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GR129_RS17740	COG0594	ribonuclease P activity
GR129_RS17745	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GR129_RS17750	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GR129_RS17755	COG0592	DNA-directed DNA polymerase activity
GR129_RS17760	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
GR129_RS17765	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GR129_RS17770	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
GR129_RS17775	COG0187	DNA topoisomerase II activity
GR129_RS17800	COG4249	Peptidase C14 caspase catalytic subunit p20
GR129_RS17800	COG2319	Wd-40 repeat
GR129_RS17835	COG0515	serine threonine protein kinase
GR129_RS17850	COG0583	DNA-binding transcription factor activity
GR129_RS17860	COG3433	isochorismatase activity
GR129_RS17860	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GR129_RS17860	COG2226	methyltransferase
GR129_RS17875	COG1960	acyl-CoA dehydrogenase activity
GR129_RS17885	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GR129_RS17890	COG1028	Short-chain dehydrogenase reductase Sdr
GR129_RS17895	COG5285	phytanoyl-CoA dioxygenase
GR129_RS17930	COG0705	Rhomboid family
GR129_RS17945	COG3764	Sortase (surface protein transpeptidase)
GR129_RS17960	COG3764	Sortase (surface protein transpeptidase)
GR129_RS17965	COG3764	Sortase (surface protein transpeptidase)
GR129_RS17970	COG0515	serine threonine protein kinase
GR129_RS17975	COG0768	penicillin binding
GR129_RS17990	COG1716	ATPase activity
GR129_RS17995	COG1716	ATPase activity
GR129_RS18005	COG0477	Major facilitator Superfamily
GR129_RS18035	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GR129_RS18040	COG2151	metal-sulfur cluster biosynthetic enzyme
GR129_RS18045	COG3396	Phenylacetate-CoA oxygenase
GR129_RS18050	COG3460	Phenylacetate-CoA oxygenase
GR129_RS18055	COG3396	Phenylacetate-CoA oxygenase
GR129_RS18080	COG1250	3-hydroxyacyl-CoA dehydrogenase
GR129_RS18090	COG1522	sequence-specific DNA binding
GR129_RS18110	COG0746	molybdenum cofactor guanylyltransferase activity
GR129_RS18115	COG0303	'Molybdopterin
GR129_RS18120	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GR129_RS18140	COG0515	serine threonine protein kinase
GR129_RS18145	COG0515	serine threonine protein kinase
GR129_RS18160	COG0022	dehydrogenase e1 component
GR129_RS18165	COG0508	dehydrogenase complex catalyzes the overall conversion of
GR129_RS18200	COG2271	Major facilitator Superfamily
GR129_RS18235	COG1362	aminopeptidase activity
GR129_RS18240	COG1960	acyl-CoA dehydrogenase activity
GR129_RS18265	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GR129_RS18275	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GR129_RS18285	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GR129_RS18290	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GR129_RS18315	COG1473	amidohydrolase
GR129_RS18335	COG1957	nucleoside hydrolase
GR129_RS18340	COG0366	Alpha amylase catalytic
GR129_RS18385	COG0701	Predicted permease
GR129_RS18410	COG1595	DNA-templated transcription, initiation
GR129_RS18420	COG1309	transcriptional regulator
GR129_RS18425	COG1028	Short-chain dehydrogenase reductase Sdr
GR129_RS18435	COG3629	intracellular signal transduction
GR129_RS18435	COG3903	Transcriptional regulator
GR129_RS18485	COG1278	Cold shock
GR129_RS18495	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GR129_RS18595	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GR129_RS18675	COG0717	Belongs to the dCTP deaminase family
GR129_RS18680	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
GR129_RS18695	COG0247	lactate metabolic process
GR129_RS18695	COG2181	nitrate reductase activity
GR129_RS18700	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GR129_RS18705	COG0443	Heat shock 70 kDa protein
GR129_RS18710	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GR129_RS18715	COG0484	heat shock protein binding
GR129_RS18720	COG0789	Transcriptional regulator
GR129_RS18725	COG4213	ABC transporter substrate-binding protein
GR129_RS18755	COG0542	response to heat
GR129_RS18785	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GR129_RS18810	COG0477	Major facilitator Superfamily
GR129_RS18820	COG3483	tryptophan 2,3-dioxygenase activity
GR129_RS18825	COG3844	kynureninase activity
GR129_RS18835	COG4585	Histidine kinase
GR129_RS18840	COG2197	response regulator
GR129_RS18865	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GR129_RS18870	COG0737	Belongs to the 5'-nucleotidase family
GR129_RS18880	COG1802	Transcriptional regulator
GR129_RS18900	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GR129_RS18905	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GR129_RS18925	COG1595	DNA-templated transcription, initiation
GR129_RS18955	COG1937	Protein conserved in bacteria
GR129_RS18970	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GR129_RS19035	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GR129_RS19050	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GR129_RS19160	COG1609	Transcriptional regulator
GR129_RS19180	COG1408	metallophosphoesterase
GR129_RS19230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GR129_RS19265	COG2267	carboxylic ester hydrolase activity
GR129_RS19280	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GR129_RS19345	COG1205	dead DEAH box helicase
GR129_RS19345	COG1111	helicase
GR129_RS19350	COG1366	Belongs to the anti-sigma-factor antagonist family
GR129_RS19355	COG2172	sigma factor antagonist activity
GR129_RS19380	COG1754	DNA topoisomerase type I activity
GR129_RS19380	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GR129_RS19385	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GR129_RS19415	COG3903	Transcriptional regulator
GR129_RS19415	COG3629	intracellular signal transduction
GR129_RS19420	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GR129_RS19420	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GR129_RS19460	COG1012	belongs to the aldehyde dehydrogenase family
GR129_RS19465	COG2318	DinB family
GR129_RS19470	COG0076	glutamate decarboxylase activity
GR129_RS19475	COG0789	Transcriptional regulator
GR129_RS19490	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GR129_RS19505	COG0037	tRNA processing
GR129_RS19520	COG0302	gtp cyclohydrolase
GR129_RS19535	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GR129_RS19565	COG0649	NAD binding
GR129_RS19580	COG2197	response regulator
GR129_RS19595	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GR129_RS19600	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GR129_RS19610	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GR129_RS19630	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GR129_RS19650	COG0542	response to heat
GR129_RS19660	COG0739	heme binding
GR129_RS19675	COG2205	protein histidine kinase activity
GR129_RS19680	COG0745	RESPONSE REGULATOR receiver
GR129_RS19690	COG1595	DNA-templated transcription, initiation
GR129_RS19695	COG1194	a g-specific adenine glycosylase
GR129_RS19705	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
GR129_RS19725	COG0248	Ppx GppA phosphatase
GR129_RS19730	COG1082	Xylose isomerase domain protein TIM barrel
GR129_RS19740	COG0129	dihydroxy-acid dehydratase activity
GR129_RS19745	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GR129_RS19745	COG0515	serine threonine protein kinase
GR129_RS19750	COG4991	sh3 domain protein
GR129_RS19770	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GR129_RS19805	COG2223	nitrite transmembrane transporter activity
GR129_RS19810	COG0123	including yeast histone deacetylase and acetoin utilization protein
GR129_RS19850	COG0560	Phosphoserine phosphatase
GR129_RS19860	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GR129_RS19865	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GR129_RS19870	COG0181	hydroxymethylbilane synthase activity
GR129_RS19875	COG1648	precorrin-2 dehydrogenase activity
GR129_RS19875	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GR129_RS19910	COG0717	Belongs to the dCTP deaminase family
GR129_RS19930	COG1309	transcriptional regulator
GR129_RS19935	COG1028	Short-chain dehydrogenase reductase Sdr
GR129_RS19945	COG0113	porphobilinogen synthase activity
GR129_RS19950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GR129_RS19990	COG0018	arginyl-trna synthetase
GR129_RS19995	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
GR129_RS20015	COG1690	Belongs to the RtcB family
GR129_RS20035	COG1742	UPF0060 membrane protein
GR129_RS20055	COG2205	protein histidine kinase activity
GR129_RS20060	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GR129_RS20060	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GR129_RS20075	COG2815	serine threonine protein kinase
GR129_RS20075	COG0515	serine threonine protein kinase
GR129_RS20090	COG1191	sigma factor activity
GR129_RS20140	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GR129_RS20145	COG0406	alpha-ribazole phosphatase activity
GR129_RS20160	COG0785	Cytochrome C biogenesis protein
GR129_RS20165	COG1333	cytochrome c biogenesis protein
GR129_RS20205	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GR129_RS20215	COG0163	prenyltransferase activity
GR129_RS20225	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
GR129_RS20230	COG1573	uracil-dna glycosylase
GR129_RS20245	COG1309	transcriptional regulator
GR129_RS20250	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GR129_RS20300	COG2175	clavaminate synthase activity
GR129_RS20305	COG1215	transferase activity, transferring glycosyl groups
GR129_RS20320	COG0438	transferase activity, transferring glycosyl groups
GR129_RS20390	COG3629	intracellular signal transduction
GR129_RS20395	COG3629	intracellular signal transduction
GR129_RS20395	COG3903	Transcriptional regulator
GR129_RS20415	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
GR129_RS20435	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
GR129_RS20445	COG2226	methyltransferase
GR129_RS20465	COG0242	peptide deformylase activity
GR129_RS20480	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GR129_RS20485	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GR129_RS20490	COG0649	NAD binding
GR129_RS20500	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GR129_RS20505	COG1034	ATP synthesis coupled electron transport
GR129_RS20510	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GR129_RS20515	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GR129_RS20520	COG0839	Belongs to the complex I subunit 6 family
GR129_RS20525	COG0713	ATP synthesis coupled electron transport
GR129_RS20530	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GR129_RS20540	COG1007	ATP synthesis coupled electron transport
GR129_RS20555	COG0514	ATP-dependent DNA helicase (RecQ)
GR129_RS20580	COG0561	phosphatase activity
GR129_RS20585	COG3953	SLT domain
GR129_RS20585	COG5412	phage tail tape measure protein
GR129_RS20625	COG0702	epimerase
GR129_RS20630	COG1013	pyruvate-flavodoxin oxidoreductase activity
GR129_RS20635	COG0674	pyruvate-flavodoxin oxidoreductase activity
GR129_RS20635	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GR129_RS20640	COG2197	response regulator
GR129_RS20655	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GR129_RS20660	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GR129_RS20665	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GR129_RS20670	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GR129_RS20675	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GR129_RS20680	COG0839	Belongs to the complex I subunit 6 family
GR129_RS20685	COG0713	ATP synthesis coupled electron transport
GR129_RS20700	COG1007	ATP synthesis coupled electron transport
GR129_RS20705	COG0501	Belongs to the peptidase M48B family
GR129_RS20720	COG2261	transglycosylase associated protein
GR129_RS20725	COG1666	GTP binding
GR129_RS20830	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GR129_RS20845	COG1595	DNA-templated transcription, initiation
GR129_RS20865	COG0702	epimerase
GR129_RS20885	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GR129_RS20890	COG2030	dehydratase
GR129_RS20935	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GR129_RS20940	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GR129_RS20945	COG0436	Aminotransferase
GR129_RS20960	COG0250	Participates in transcription elongation, termination and antitermination
GR129_RS20970	COG0081	regulation of translation
GR129_RS20980	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GR129_RS20985	COG0222	ribosome binding
GR129_RS20990	COG0085	RNA polymerase activity
GR129_RS20995	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GR129_RS21000	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GR129_RS21005	COG0049	tRNA binding
GR129_RS21010	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GR129_RS21065	COG0051	transcription antitermination factor activity, RNA binding
GR129_RS21070	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GR129_RS21075	COG0088	Forms part of the polypeptide exit tunnel
GR129_RS21080	COG0089	rRNA binding
GR129_RS21085	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GR129_RS21090	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GR129_RS21095	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GR129_RS21100	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GR129_RS21105	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GR129_RS21110	COG0255	Belongs to the universal ribosomal protein uL29 family
GR129_RS21115	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GR129_RS21120	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GR129_RS21125	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GR129_RS21130	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GR129_RS21135	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GR129_RS21145	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GR129_RS21150	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GR129_RS21155	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GR129_RS21160	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GR129_RS21165	COG1841	ribosomal large subunit assembly
GR129_RS21170	COG0200	Binds to the 23S rRNA
GR129_RS21180	COG0563	adenylate kinase activity
GR129_RS21190	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GR129_RS21195	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GR129_RS21200	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GR129_RS21205	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GR129_RS21210	COG0202	RNA polymerase activity
GR129_RS21215	COG0203	ribosomal protein L17
GR129_RS21220	COG0101	tRNA pseudouridine synthase activity
GR129_RS21230	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GR129_RS21235	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GR129_RS21240	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GR129_RS21245	COG1072	(Pantothenic acid kinase))
GR129_RS21255	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GR129_RS21260	COG1028	Short-chain dehydrogenase reductase Sdr
GR129_RS21265	COG0736	holo-[acyl-carrier-protein] synthase activity
GR129_RS21275	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GR129_RS21285	COG0802	atpase or kinase
GR129_RS21305	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GR129_RS21335	COG0726	polysaccharide deacetylase
GR129_RS21340	COG0726	polysaccharide deacetylase
GR129_RS21350	COG0459	protein refolding
GR129_RS21360	COG4221	oxidoreductase activity
GR129_RS21370	COG0583	DNA-binding transcription factor activity
GR129_RS21385	COG1595	DNA-templated transcription, initiation
GR129_RS21395	COG0516	GMP reductase activity
GR129_RS21410	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GR129_RS21420	COG0515	serine threonine protein kinase
GR129_RS21420	COG2815	serine threonine protein kinase
GR129_RS21425	COG0515	serine threonine protein kinase
GR129_RS21430	COG0515	serine threonine protein kinase
GR129_RS21440	COG2207	Transcriptional regulator
GR129_RS21445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GR129_RS21450	COG0515	serine threonine protein kinase
GR129_RS21455	COG1012	belongs to the aldehyde dehydrogenase family
GR129_RS21470	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GR129_RS21470	COG0519	Catalyzes the synthesis of GMP from XMP
GR129_RS21510	COG2197	response regulator
GR129_RS21530	COG0739	heme binding
GR129_RS21555	COG0714	Associated with various cellular activities
GR129_RS21565	COG3552	Protein containing von Willebrand factor type A (VWA) domain
GR129_RS21570	COG0045	succinate-CoA ligase (ADP-forming) activity
GR129_RS21600	COG0138	bifunctional purine biosynthesis protein purh
GR129_RS21625	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GR129_RS21640	COG0039	L-malate dehydrogenase activity
GR129_RS21645	COG0477	Major facilitator Superfamily
GR129_RS21665	COG0517	IMP dehydrogenase activity
GR129_RS21665	COG4175	Glycine betaine
GR129_RS21670	COG4176	ABC-type proline glycine betaine transport system permease component
GR129_RS21685	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GR129_RS21690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GR129_RS21710	COG0754	glutathionylspermidine amidase activity
GR129_RS21715	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GR129_RS21720	COG0180	Tryptophanyl-tRNA synthetase
GR129_RS21735	COG1295	ribonuclease BN
GR129_RS21760	COG1309	transcriptional regulator
GR129_RS21780	COG1053	succinate dehydrogenase
GR129_RS21790	COG2009	succinate dehydrogenase
GR129_RS21800	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GR129_RS21825	COG1595	DNA-templated transcription, initiation
GR129_RS21850	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GR129_RS21860	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GR129_RS21870	COG1216	Glycosyl transferase, family 2
GR129_RS21885	COG2089	acid synthase
GR129_RS21900	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
GR129_RS21900	COG1473	amidohydrolase
GR129_RS21950	COG2814	Major facilitator Superfamily
GR129_RS21955	COG0583	DNA-binding transcription factor activity
GR129_RS21965	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GR129_RS21990	COG2205	protein histidine kinase activity
GR129_RS21995	COG0745	RESPONSE REGULATOR receiver
GR129_RS22000	COG1595	DNA-templated transcription, initiation
GR129_RS22015	COG1012	belongs to the aldehyde dehydrogenase family
GR129_RS22020	COG1012	belongs to the aldehyde dehydrogenase family
GR129_RS22025	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GR129_RS22035	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GR129_RS22060	COG4770	biotin carboxylase activity
GR129_RS22070	COG0424	maF-like protein
GR129_RS22085	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GR129_RS22100	COG2267	carboxylic ester hydrolase activity
GR129_RS22110	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
GR129_RS22120	COG1024	Enoyl-CoA hydratase
GR129_RS22130	COG2986	histidine ammonia-lyase
GR129_RS22160	COG1136	(ABC) transporter
GR129_RS22170	COG1064	alcohol dehydrogenase
GR129_RS22195	COG1595	DNA-templated transcription, initiation
GR129_RS22205	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GR129_RS22210	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GR129_RS22220	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GR129_RS22245	COG1331	Highly conserved protein containing a thioredoxin domain
GR129_RS22260	COG1309	transcriptional regulator
GR129_RS22270	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
GR129_RS22280	COG0436	Aminotransferase
GR129_RS22295	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
GR129_RS22310	COG1414	Transcriptional regulator
GR129_RS22315	COG0251	oxidation-reduction process
GR129_RS22375	COG2894	cell division
GR129_RS22405	COG3920	Histidine kinase
GR129_RS22410	COG2197	response regulator
GR129_RS22430	COG2885	chlorophyll binding
GR129_RS22450	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GR129_RS22455	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GR129_RS22470	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GR129_RS22475	COG0450	alkyl hydroperoxide reductase
GR129_RS22490	COG1136	(ABC) transporter
GR129_RS22500	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GR129_RS22515	COG0114	fumarate hydratase activity
GR129_RS22520	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GR129_RS22520	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GR129_RS22545	COG0778	Nitroreductase
GR129_RS22550	COG1722	exodeoxyribonuclease VII activity
GR129_RS22555	COG1570	exodeoxyribonuclease VII activity
GR129_RS22560	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GR129_RS22575	COG0012	GTP binding
GR129_RS22610	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
GR129_RS22620	COG2226	methyltransferase
GR129_RS22665	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GR129_RS22735	COG4166	transmembrane transport
GR129_RS22745	COG0444	Belongs to the ABC transporter superfamily
GR129_RS22750	COG4608	Belongs to the ABC transporter superfamily
GR129_RS22760	COG0346	lactoylglutathione lyase activity
GR129_RS22765	COG4608	Belongs to the ABC transporter superfamily
GR129_RS22770	COG0444	Belongs to the ABC transporter superfamily
GR129_RS22780	COG0747	negative chemotaxis
GR129_RS22790	COG4166	transmembrane transport
GR129_RS22795	COG0601	transmembrane transport
GR129_RS22805	COG0444	Belongs to the ABC transporter superfamily
GR129_RS22810	COG4608	Belongs to the ABC transporter superfamily
GR129_RS22825	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GR129_RS22840	COG1131	(ABC) transporter
GR129_RS22850	COG4585	Histidine kinase
GR129_RS22855	COG2197	response regulator
GR129_RS22890	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GR129_RS22895	COG1611	Belongs to the LOG family
GR129_RS22900	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GR129_RS22910	COG0519	Catalyzes the synthesis of GMP from XMP
GR129_RS22915	COG1024	Enoyl-CoA hydratase
GR129_RS22930	COG1595	DNA-templated transcription, initiation
GR129_RS22940	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GR129_RS22945	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GR129_RS22980	COG0598	Magnesium transport protein CorA
GR129_RS22990	COG2814	Major facilitator Superfamily
GR129_RS23005	COG2095	MarC family integral membrane protein
GR129_RS23010	COG1432	Conserved Protein
GR129_RS23065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GR129_RS23070	COG0601	transmembrane transport
GR129_RS23080	COG0438	transferase activity, transferring glycosyl groups
GR129_RS23105	COG1846	Transcriptional regulator
GR129_RS23140	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GR129_RS23145	COG2816	NAD+ diphosphatase activity
GR129_RS23180	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GR129_RS23230	COG3480	Lon protease (S16) C-terminal proteolytic domain
GR129_RS23240	COG1615	UPF0182 protein
GR129_RS23265	COG0753	catalase activity
GR129_RS23275	COG0483	inositol monophosphate 1-phosphatase activity
GR129_RS23285	COG2076	Multidrug Resistance protein
GR129_RS23295	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GR129_RS23305	COG2135	peptidase activity
GR129_RS23315	COG1595	DNA-templated transcription, initiation
GR129_RS23320	COG5662	AntiSigma factor
GR129_RS23330	COG0242	peptide deformylase activity
GR129_RS23340	COG2124	cytochrome p450
GR129_RS23345	COG4977	sequence-specific DNA binding
GR129_RS23375	COG2188	Transcriptional regulator
GR129_RS23395	COG1597	lipid kinase activity
GR129_RS23410	COG2172	sigma factor antagonist activity
GR129_RS23425	COG2515	1-aminocyclopropane-1-carboxylate deaminase
GR129_RS23430	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GR129_RS23465	COG1335	isochorismatase
GR129_RS23515	COG4106	trans-aconitate 2-methyltransferase activity
GR129_RS23520	COG1126	abc transporter atp-binding protein
GR129_RS23535	COG0281	malic enzyme
GR129_RS23540	COG0604	alcohol dehydrogenase
GR129_RS23555	COG0567	Dehydrogenase, E1 component
GR129_RS23555	COG0508	dehydrogenase complex catalyzes the overall conversion of
GR129_RS23560	COG2205	protein histidine kinase activity
GR129_RS23565	COG0745	RESPONSE REGULATOR receiver
GR129_RS23580	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GR129_RS23685	COG0768	penicillin binding
GR129_RS23715	COG1793	dna ligase
GR129_RS23715	COG3285	dna ligase
GR129_RS23720	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
GR129_RS23745	COG0395	ABC-type sugar transport system, permease component
GR129_RS23750	COG4209	transmembrane transport
GR129_RS23755	COG1609	Transcriptional regulator
GR129_RS23765	COG3629	intracellular signal transduction
GR129_RS23765	COG3903	Transcriptional regulator
GR129_RS23800	COG1720	tRNA m6t6A37 methyltransferase activity
GR129_RS23810	COG0626	cystathionine gamma-synthase activity
GR129_RS23825	COG1181	Belongs to the D-alanine--D-alanine ligase family
GR129_RS23830	COG1720	tRNA m6t6A37 methyltransferase activity
GR129_RS23870	COG0018	arginyl-trna synthetase
GR129_RS23875	COG0019	diaminopimelate decarboxylase activity
GR129_RS23880	COG0460	homoserine dehydrogenase
GR129_RS23885	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GR129_RS23890	COG0083	homoserine kinase activity
GR129_RS23905	COG0254	rRNA binding
GR129_RS23910	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GR129_RS23915	COG2890	protein-(glutamine-N5) methyltransferase activity
GR129_RS23925	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GR129_RS23930	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GR129_RS23935	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GR129_RS23950	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GR129_RS23955	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GR129_RS23960	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GR129_RS23965	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GR129_RS23975	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GR129_RS23980	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GR129_RS24020	COG1250	3-hydroxyacyl-CoA dehydrogenase
GR129_RS24035	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
GR129_RS24090	COG0183	Belongs to the thiolase family
GR129_RS24155	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GR129_RS24155	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GR129_RS24190	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GR129_RS24195	COG0280	phosphate acetyltransferase
GR129_RS24195	COG0857	belongs to the CobB CobQ family
GR129_RS24200	COG0205	6-phosphofructokinase activity
GR129_RS24210	COG4565	transcriptional regulatory protein
GR129_RS24215	COG3290	protein histidine kinase activity
GR129_RS24220	COG1301	dicarboxylic acid transport
GR129_RS24230	COG0477	Major facilitator Superfamily
GR129_RS24255	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GR129_RS24260	COG3281	Trehalose synthase
GR129_RS24270	COG0366	Alpha amylase catalytic
GR129_RS24275	COG0058	SHG alpha-glucan phosphorylase activity
GR129_RS24300	COG4585	Histidine kinase
GR129_RS24310	COG1131	(ABC) transporter
GR129_RS24315	COG1132	(ABC) transporter
GR129_RS24320	COG1132	(ABC) transporter
GR129_RS24340	COG1215	transferase activity, transferring glycosyl groups
GR129_RS24360	COG1376	ErfK ybiS ycfS ynhG family protein
GR129_RS24370	COG1024	Enoyl-CoA hydratase
GR129_RS24400	COG3409	Peptidoglycan-binding domain 1 protein
GR129_RS24400	COG3757	hydrolase, family 25
GR129_RS24415	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GR129_RS24420	COG0509	glycine decarboxylation via glycine cleavage system
GR129_RS24425	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GR129_RS24445	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GR129_RS24450	COG0747	negative chemotaxis
GR129_RS24465	COG4608	Belongs to the ABC transporter superfamily
GR129_RS24475	COG2860	membrane
GR129_RS24495	COG0583	DNA-binding transcription factor activity
GR129_RS24535	COG0482	sulfurtransferase activity
GR129_RS24550	COG1611	Belongs to the LOG family
GR129_RS24555	COG4221	oxidoreductase activity
GR129_RS24565	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GR129_RS24590	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GR129_RS24595	COG0154	amidase activity
GR129_RS24605	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GR129_RS24610	COG2409	Drug exporters of the RND superfamily
GR129_RS24630	COG2133	pyrroloquinoline quinone binding
GR129_RS24635	COG0667	Aldo Keto reductase
GR129_RS24660	COG0440	acetolactate synthase activity
GR129_RS24665	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GR129_RS24675	COG3835	regulator
GR129_RS24685	COG1012	belongs to the aldehyde dehydrogenase family
GR129_RS24705	COG0473	3-isopropylmalate dehydrogenase activity
GR129_RS24710	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GR129_RS24720	COG0804	urea catabolic process
GR129_RS24725	COG2957	Belongs to the agmatine deiminase family
GR129_RS24745	COG0477	Major facilitator Superfamily
GR129_RS24750	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GR129_RS24765	COG1472	Belongs to the glycosyl hydrolase 3 family
GR129_RS24785	COG2353	YceI-like domain
GR129_RS24790	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GR129_RS24815	COG2018	Roadblock/LC7 domain
GR129_RS24835	COG2018	Roadblock/LC7 domain
GR129_RS24840	COG5002	protein histidine kinase activity
GR129_RS24855	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GR129_RS24895	COG1414	Transcriptional regulator
GR129_RS24900	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GR129_RS24905	COG0066	3-isopropylmalate dehydratase activity
GR129_RS24915	COG0776	regulation of translation
GR129_RS24935	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GR129_RS24940	COG1181	Belongs to the D-alanine--D-alanine ligase family
GR129_RS24960	COG0351	phosphomethylpyrimidine kinase
GR129_RS24970	COG1846	Transcriptional regulator
GR129_RS24975	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GR129_RS24980	COG1461	Dihydroxyacetone kinase
GR129_RS25000	COG0742	ribosomal rna small subunit methyltransferase
GR129_RS25005	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GR129_RS25020	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GR129_RS25025	COG0571	ribonuclease III activity
GR129_RS25030	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GR129_RS25035	COG1733	regulation of RNA biosynthetic process
GR129_RS25050	COG1254	Belongs to the acylphosphatase family
GR129_RS25070	COG0477	Major facilitator Superfamily
GR129_RS25085	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GR129_RS25115	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GR129_RS25125	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GR129_RS25140	COG0228	four-way junction DNA binding
GR129_RS25145	COG1837	Belongs to the UPF0109 family
GR129_RS25150	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GR129_RS25155	COG0336	Belongs to the RNA methyltransferase TrmD family
GR129_RS25160	COG0335	large ribosomal subunit rRNA binding
GR129_RS25175	COG0681	Belongs to the peptidase S26 family
GR129_RS25185	COG1051	belongs to the nudix hydrolase family
GR129_RS25195	COG0792	nuclease activity
GR129_RS25200	COG0606	chelatase, subunit chli
GR129_RS25210	COG1191	sigma factor activity
GR129_RS25225	COG0052	Belongs to the universal ribosomal protein uS2 family
GR129_RS25235	COG0528	UMP kinase activity
GR129_RS25240	COG0233	cytoplasmic translational termination
GR129_RS25245	COG0575	Belongs to the CDS family
GR129_RS25255	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GR129_RS25265	COG4208	sulfate ABC transporter
GR129_RS25270	COG3842	ATPase activity
GR129_RS25290	COG4181	ATPase activity
GR129_RS25295	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GR129_RS25305	COG1012	belongs to the aldehyde dehydrogenase family
GR129_RS25320	COG0395	ABC-type sugar transport system, permease component
GR129_RS25340	COG3876	Protein conserved in bacteria
GR129_RS25355	COG1366	Belongs to the anti-sigma-factor antagonist family
GR129_RS25360	COG1366	Belongs to the anti-sigma-factor antagonist family
GR129_RS25365	COG2172	sigma factor antagonist activity
GR129_RS25375	COG0784	Response regulator, receiver
GR129_RS25375	COG2198	Histidine kinase
GR129_RS25375	COG5002	protein histidine kinase activity
GR129_RS25385	COG0584	glycerophosphoryl diester phosphodiesterase
GR129_RS25390	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GR129_RS25415	COG3842	ATPase activity
GR129_RS25420	COG1176	ABC-type spermidine putrescine transport system, permease component I
GR129_RS25425	COG1177	transmembrane transport
GR129_RS25430	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GR129_RS25465	COG1012	belongs to the aldehyde dehydrogenase family
GR129_RS25510	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GR129_RS25515	COG0750	zinc metalloprotease
GR129_RS25520	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GR129_RS25580	COG1247	-acetyltransferase
GR129_RS25585	COG0442	prolyl-tRNA aminoacylation
GR129_RS25590	COG1028	Short-chain dehydrogenase reductase Sdr
GR129_RS25595	COG0583	DNA-binding transcription factor activity
GR129_RS25615	COG0779	Required for maturation of 30S ribosomal subunits
GR129_RS25630	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GR129_RS25640	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GR129_RS25645	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GR129_RS25660	COG0455	bacterial-type flagellum organization
GR129_RS25695	COG1404	Belongs to the peptidase S8 family
GR129_RS25710	COG1674	ftsk spoiiie
GR129_RS25725	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GR129_RS25730	COG1185	polyribonucleotide nucleotidyltransferase activity
GR129_RS25735	COG0612	Peptidase, M16
GR129_RS25740	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GR129_RS25760	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
GR129_RS25765	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GR129_RS25770	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GR129_RS25800	COG2770	Histidine kinase
GR129_RS25800	COG2208	phosphoserine phosphatase activity
GR129_RS25820	COG1674	ftsk spoiiie
GR129_RS25830	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GR129_RS25840	COG1058	Belongs to the CinA family
GR129_RS25840	COG1546	Belongs to the CinA family
GR129_RS25845	COG1396	sequence-specific DNA binding
GR129_RS25850	COG0783	Belongs to the Dps family
GR129_RS25860	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GR129_RS25865	COG1201	RNA secondary structure unwinding
GR129_RS25890	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GR129_RS25895	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GR129_RS25900	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GR129_RS25930	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GR129_RS25945	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GR129_RS25955	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GR129_RS25970	COG0765	amino acid transport
GR129_RS25975	COG0765	amino acid transport
GR129_RS25980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GR129_RS25985	COG1126	abc transporter atp-binding protein
GR129_RS25990	COG0745	RESPONSE REGULATOR receiver
GR129_RS25995	COG2205	protein histidine kinase activity
GR129_RS26020	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GR129_RS26040	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GR129_RS26050	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GR129_RS26055	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GR129_RS26065	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GR129_RS26095	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GR129_RS26100	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GR129_RS26105	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GR129_RS26125	COG0588	phosphoglycerate mutase activity
GR129_RS26140	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GR129_RS26175	COG2186	Transcriptional regulator
GR129_RS26180	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GR129_RS26195	COG0187	DNA topoisomerase II activity
GR129_RS26220	COG2197	response regulator
GR129_RS26230	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GR129_RS26235	COG4565	transcriptional regulatory protein
GR129_RS26245	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GR129_RS26255	COG3290	protein histidine kinase activity
GR129_RS26270	COG0372	Belongs to the citrate synthase family
GR129_RS26280	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GR129_RS26285	COG0612	Peptidase, M16
GR129_RS26300	COG1802	Transcriptional regulator
GR129_RS26305	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GR129_RS26325	COG1435	thymidine kinase activity
GR129_RS26370	COG0745	RESPONSE REGULATOR receiver
GR129_RS26375	COG2205	protein histidine kinase activity
GR129_RS26400	COG0756	dUTP diphosphatase activity
GR129_RS26435	COG0569	domain protein
GR129_RS26440	COG0531	amino acid
GR129_RS26445	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GR129_RS26470	COG1819	glycosyl
GR129_RS26490	COG2192	nodulation
GR129_RS26495	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GR129_RS26515	COG0318	PFAM AMP-dependent synthetase and ligase
GR129_RS26550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GR129_RS26560	COG1132	(ABC) transporter
GR129_RS26565	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GR129_RS26570	COG1809	phosphosulfolactate synthase activity
GR129_RS26580	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GR129_RS26590	COG0165	Argininosuccinate lyase
GR129_RS26605	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GR129_RS26650	COG2175	clavaminate synthase activity
GR129_RS26660	COG3251	PFAM MbtH domain protein
GR129_RS26690	COG1136	(ABC) transporter
GR129_RS26700	COG2197	response regulator
GR129_RS26705	COG0438	transferase activity, transferring glycosyl groups
GR129_RS26750	COG3903	Transcriptional regulator
GR129_RS26750	COG3629	intracellular signal transduction
GR129_RS26810	COG1846	Transcriptional regulator
GR129_RS26850	COG1799	cell septum assembly
GR129_RS26880	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GR129_RS26895	COG2235	arginine
GR129_RS26900	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GR129_RS26905	COG0531	amino acid
GR129_RS26915	COG1024	Enoyl-CoA hydratase
GR129_RS26995	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GR129_RS27000	COG3629	intracellular signal transduction
GR129_RS27020	COG2814	Major facilitator Superfamily
GR129_RS27025	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GR129_RS27030	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GR129_RS27035	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GR129_RS27045	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GR129_RS27050	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GR129_RS27055	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GR129_RS27090	COG1012	belongs to the aldehyde dehydrogenase family
GR129_RS27105	COG0318	PFAM AMP-dependent synthetase and ligase
GR129_RS27120	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GR129_RS27125	COG0477	Major facilitator Superfamily
GR129_RS27130	COG0477	Major facilitator Superfamily
GR129_RS27145	COG0477	Major facilitator Superfamily
GR129_RS27155	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GR129_RS27200	COG2188	Transcriptional regulator
GR129_RS27210	COG1175	transmembrane transport
GR129_RS27220	COG1472	Belongs to the glycosyl hydrolase 3 family
GR129_RS27250	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GR129_RS27285	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GR129_RS27290	COG1522	sequence-specific DNA binding
GR129_RS27305	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GR129_RS27375	COG1175	transmembrane transport
GR129_RS27380	COG0395	ABC-type sugar transport system, permease component
GR129_RS27385	COG1940	carbohydrate kinase activity
GR129_RS27390	COG4213	ABC transporter substrate-binding protein
GR129_RS27400	COG4214	carbohydrate transport
GR129_RS27410	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GR129_RS27415	COG0531	amino acid
GR129_RS27430	COG2843	Capsule synthesis protein
GR129_RS27465	COG0183	Belongs to the thiolase family
GR129_RS27470	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
GR129_RS27485	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GR129_RS27495	COG0446	pyridine nucleotide-disulphide oxidoreductase
GR129_RS27520	COG3220	belongs to the UPF0276 family
GR129_RS27555	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GR129_RS27590	COG4152	abc transporter atp-binding protein
GR129_RS27605	COG0723	plastoquinol--plastocyanin reductase activity
GR129_RS27605	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GR129_RS27640	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GR129_RS27645	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GR129_RS27655	COG1174	glycine betaine transport
GR129_RS27660	COG1174	glycine betaine transport
GR129_RS27730	COG3173	Aminoglycoside phosphotransferase
GR129_RS27785	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GR129_RS27805	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
GR129_RS27835	COG0175	sulfate reduction
GR129_RS27845	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GR129_RS27850	COG0456	acetyltransferase
GR129_RS27865	COG1960	acyl-CoA dehydrogenase activity
GR129_RS27880	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GR129_RS27900	COG4221	oxidoreductase activity
GR129_RS27915	COG2040	homocysteine
GR129_RS27935	COG0277	FAD linked oxidase domain protein
GR129_RS27955	COG1942	4-Oxalocrotonate Tautomerase
GR129_RS27960	COG2814	Major facilitator Superfamily
GR129_RS27965	COG0583	DNA-binding transcription factor activity
GR129_RS27980	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GR129_RS27980	COG0473	3-isopropylmalate dehydrogenase activity
GR129_RS27990	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GR129_RS28005	COG1162	GTPase activity
GR129_RS28025	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GR129_RS28055	COG0028	Belongs to the TPP enzyme family
GR129_RS28070	COG1802	Transcriptional regulator
GR129_RS28095	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GR129_RS28100	COG2252	PERMEase
GR129_RS28130	COG0726	polysaccharide deacetylase
GR129_RS28160	COG2197	response regulator
GR129_RS28165	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GR129_RS28170	COG0318	PFAM AMP-dependent synthetase and ligase
GR129_RS28180	COG3960	tartronate-semialdehyde synthase activity
GR129_RS28195	COG0753	catalase activity
GR129_RS28200	COG2084	Dehydrogenase
GR129_RS28205	COG3622	Belongs to the hyi family
GR129_RS28225	COG2351	hydroxyisourate hydrolase activity
GR129_RS28240	COG2233	PERMEase
GR129_RS28260	COG0406	alpha-ribazole phosphatase activity
GR129_RS28270	COG0436	Aminotransferase
GR129_RS28275	COG1733	regulation of RNA biosynthetic process
GR129_RS28295	COG4264	IucA IucC family
GR129_RS28345	COG1414	Transcriptional regulator
GR129_RS28350	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GR129_RS28355	COG4266	Belongs to the allantoicase family
GR129_RS28390	COG0673	inositol 2-dehydrogenase activity
GR129_RS28410	COG1129	ABC transporter
GR129_RS28415	COG1940	carbohydrate kinase activity
GR129_RS28425	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GR129_RS28440	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GR129_RS28445	COG0069	glutamate synthase activity
GR129_RS28450	COG0017	Asparaginyl-tRNA synthetase
GR129_RS28455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GR129_RS28500	COG2205	protein histidine kinase activity
GR129_RS28530	COG1131	(ABC) transporter
GR129_RS28560	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GR129_RS28595	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GR129_RS28620	COG0405	Gamma-glutamyltransferase
GR129_RS28645	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GR129_RS28655	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GR129_RS28660	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GR129_RS28670	COG1953	Uracil, thiamine, allantoin
GR129_RS28710	COG0095	Lipoate-protein ligase
GR129_RS28720	COG0531	amino acid
GR129_RS28730	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
GR129_RS28735	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
GR129_RS28740	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
GR129_RS28770	COG0583	DNA-binding transcription factor activity
GR129_RS28815	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GR129_RS28825	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GR129_RS28830	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GR129_RS28845	COG1929	Belongs to the glycerate kinase type-1 family
GR129_RS28855	COG0688	phosphatidylethanolamine metabolic process
GR129_RS28860	COG1960	acyl-CoA dehydrogenase activity
GR129_RS28870	COG2301	Belongs to the HpcH HpaI aldolase family
GR129_RS28890	COG1250	3-hydroxyacyl-CoA dehydrogenase
GR129_RS28905	COG1295	ribonuclease BN
GR129_RS28940	COG4106	trans-aconitate 2-methyltransferase activity
GR129_RS28945	COG2362	D-Aminopeptidase
GR129_RS28950	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GR129_RS28960	COG1619	proteins homologs of microcin C7 resistance protein MccF
GR129_RS28985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GR129_RS28990	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GR129_RS29065	COG0488	(ABC) transporter
GR129_RS29085	COG0028	Belongs to the TPP enzyme family
GR129_RS29110	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GR129_RS29140	COG2154	pterin-4-alpha-carbinolamine dehydratase
GR129_RS29145	COG4106	trans-aconitate 2-methyltransferase activity
GR129_RS29145	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GR129_RS29175	COG0656	L-ascorbic acid biosynthetic process
GR129_RS29205	COG1846	Transcriptional regulator
GR129_RS29215	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GR129_RS29220	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GR129_RS29250	COG2850	peptidyl-arginine hydroxylation
GR129_RS29270	COG3537	Alpha-1,2-mannosidase
GR129_RS29275	COG1335	isochorismatase
GR129_RS29310	COG0477	Major facilitator Superfamily
GR129_RS29370	COG1175	transmembrane transport
GR129_RS29375	COG0395	ABC-type sugar transport system, permease component
GR129_RS29380	COG2723	6-phospho-beta-galactosidase activity
GR129_RS29405	COG3467	pyridoxamine 5'-phosphate
GR129_RS29410	COG2084	Dehydrogenase
GR129_RS29425	COG0406	alpha-ribazole phosphatase activity
GR129_RS29430	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
GR129_RS29435	COG0166	Belongs to the GPI family
GR129_RS29450	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GR129_RS29475	COG1486	melibiose metabolic process
GR129_RS29505	COG3511	phospholipase C
GR129_RS29545	COG0477	Major facilitator Superfamily
GR129_RS29565	COG1793	dna ligase
GR129_RS29595	COG1834	amidinotransferase
GR129_RS29600	COG0488	(ABC) transporter
GR129_RS29625	COG1515	deoxyribonuclease V activity
GR129_RS29635	COG3268	Saccharopine dehydrogenase
GR129_RS29640	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GR129_RS29645	COG0183	Belongs to the thiolase family
GR129_RS29650	COG1250	3-hydroxyacyl-CoA dehydrogenase
GR129_RS29650	COG1024	Enoyl-CoA hydratase
GR129_RS29660	COG1113	amino acid transport
GR129_RS29675	COG2936	dipeptidyl-peptidase activity
GR129_RS29685	COG0488	(ABC) transporter
GR129_RS29695	COG2183	response to ionizing radiation
GR129_RS29700	COG4977	sequence-specific DNA binding
GR129_RS29715	COG1024	Enoyl-CoA hydratase
GR129_RS29730	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GR129_RS29775	COG1134	teichoic acid transport
GR129_RS29780	COG1562	ergosterol biosynthetic process
GR129_RS29790	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
GR129_RS29800	COG1657	PFAM Prenyltransferase squalene oxidase
GR129_RS29815	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GR129_RS29845	COG2755	lipolytic protein G-D-S-L family
GR129_RS29885	COG1131	(ABC) transporter
GR129_RS29890	COG0842	Transport permease protein
GR129_RS29905	COG1473	amidohydrolase
GR129_RS29965	COG0156	8-amino-7-oxononanoate synthase activity
GR129_RS29970	COG0583	DNA-binding transcription factor activity
GR129_RS29985	COG3958	Transketolase
GR129_RS29990	COG3959	Transketolase, thiamine diphosphate binding domain
GR129_RS30000	COG1028	Short-chain dehydrogenase reductase Sdr
GR129_RS30005	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
GR129_RS30030	COG3629	intracellular signal transduction
GR129_RS30030	COG3903	Transcriptional regulator
GR129_RS30080	COG0174	glutamine synthetase
GR129_RS30090	COG0561	phosphatase activity
GR129_RS30115	COG2267	carboxylic ester hydrolase activity
GR129_RS30125	COG0318	PFAM AMP-dependent synthetase and ligase
GR129_RS30165	COG0318	PFAM AMP-dependent synthetase and ligase
GR129_RS30170	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GR129_RS30190	COG0156	8-amino-7-oxononanoate synthase activity
GR129_RS30195	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GR129_RS30200	COG1028	Short-chain dehydrogenase reductase Sdr
GR129_RS30225	COG3173	Aminoglycoside phosphotransferase
GR129_RS30245	COG0151	Belongs to the GarS family
GR129_RS30270	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GR129_RS30280	COG1509	lysine 2,3-aminomutase activity
GR129_RS30305	COG1132	(ABC) transporter
GR129_RS30310	COG1132	(ABC) transporter
GR129_RS30335	COG0180	Tryptophanyl-tRNA synthetase
GR129_RS30420	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GR129_RS30450	COG2124	cytochrome p450
GR129_RS30470	COG0673	inositol 2-dehydrogenase activity
GR129_RS30475	COG0673	inositol 2-dehydrogenase activity
GR129_RS30540	COG0028	Belongs to the TPP enzyme family
GR129_RS30580	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GR129_RS30600	COG0154	amidase activity
GR129_RS30605	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GR129_RS30615	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GR129_RS30615	COG2080	2 iron, 2 sulfur cluster binding
GR129_RS30635	COG0577	efflux transmembrane transporter activity
GR129_RS30640	COG4585	Histidine kinase
GR129_RS30645	COG2197	response regulator
GR129_RS30650	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GR129_RS30655	COG0702	epimerase
GR129_RS30665	COG0531	amino acid
GR129_RS30670	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GR129_RS30720	COG2197	response regulator
GR129_RS30800	COG2124	cytochrome p450
GR129_RS30815	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GR129_RS30830	COG2838	Isocitrate dehydrogenase
GR129_RS30840	COG0668	transmembrane transport
GR129_RS30845	COG0531	amino acid
GR129_RS30855	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GR129_RS30875	COG1024	Enoyl-CoA hydratase
GR129_RS30885	COG1132	(ABC) transporter
GR129_RS30905	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GR129_RS30910	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GR129_RS30980	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GR129_RS31015	COG2079	MmgE PrpD family protein
GR129_RS31020	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GR129_RS31040	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GR129_RS31070	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GR129_RS31080	COG1028	Short-chain dehydrogenase reductase Sdr
GR129_RS31080	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GR129_RS31080	COG4221	oxidoreductase activity
GR129_RS31080	COG3321	synthase
GR129_RS31135	COG1408	metallophosphoesterase
GR129_RS31165	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GR129_RS31175	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GR129_RS31185	COG0254	rRNA binding
GR129_RS31190	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GR129_RS31200	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GR129_RS31210	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GR129_RS31220	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GR129_RS31225	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GR129_RS31235	COG1132	(ABC) transporter
GR129_RS31260	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
GR129_RS31260	COG2308	Evidence 4 Homologs of previously reported genes of
GR129_RS31300	COG0601	transmembrane transport
GR129_RS31335	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GR129_RS31355	COG3537	Alpha-1,2-mannosidase
GR129_RS31380	COG0154	amidase activity
GR129_RS31400	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GR129_RS31415	COG0531	amino acid
GR129_RS31435	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GR129_RS31435	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GR129_RS31475	COG0583	DNA-binding transcription factor activity
GR129_RS31485	COG1053	succinate dehydrogenase
GR129_RS31490	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GR129_RS31520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GR129_RS31530	COG3360	Dodecin
GR129_RS31540	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
GR129_RS31545	COG0121	glutamine amidotransferase
GR129_RS31550	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GR129_RS31590	COG1028	Short-chain dehydrogenase reductase Sdr
GR129_RS31620	COG4555	ABC transporter
GR129_RS31645	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GR129_RS31660	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GR129_RS31705	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GR129_RS31715	COG0242	peptide deformylase activity
GR129_RS31725	COG3608	succinylglutamate desuccinylase aspartoacylase
GR129_RS31725	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GR129_RS31745	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GR129_RS31745	COG3608	succinylglutamate desuccinylase aspartoacylase
GR129_RS31780	COG0651	ATP synthesis coupled electron transport
GR129_RS31800	COG3260	NADH ubiquinone oxidoreductase 20
GR129_RS31805	COG2824	Alkylphosphonate utilization operon protein PhnA
GR129_RS31820	COG0659	secondary active sulfate transmembrane transporter activity
GR129_RS31835	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GR129_RS31840	COG1993	acr, cog1993
GR129_RS31845	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GR129_RS31850	COG0326	Molecular chaperone. Has ATPase activity
GR129_RS31900	COG2124	cytochrome p450
GR129_RS31925	COG2197	response regulator
GR129_RS31930	COG2197	response regulator
GR129_RS31935	COG3340	Belongs to the peptidase S51 family
GR129_RS31945	COG3251	PFAM MbtH domain protein
GR129_RS31960	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GR129_RS31985	COG1028	Short-chain dehydrogenase reductase Sdr
GR129_RS31995	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GR129_RS32000	COG1250	3-hydroxyacyl-CoA dehydrogenase
GR129_RS32010	COG0148	phosphopyruvate hydratase activity
GR129_RS32015	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GR129_RS32060	COG0671	phosphoesterase, PA-phosphatase related
GR129_RS32115	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GR129_RS32120	COG1028	Short-chain dehydrogenase reductase Sdr
GR129_RS32125	COG1021	2,3-dihydroxybenzoate-AMP ligase
GR129_RS32130	COG1535	isochorismatase
GR129_RS32130	COG3433	isochorismatase activity
GR129_RS32135	COG3486	L-lysine 6-monooxygenase (NADPH) activity
GR129_RS32155	COG1535	isochorismatase
GR129_RS32155	COG3433	isochorismatase activity
GR129_RS32170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GR129_RS32175	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GR129_RS32180	COG1120	ATPase activity
GR129_RS32190	COG0477	Major facilitator Superfamily
GR129_RS32195	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GR129_RS32210	COG4251	negative regulation of phosphorylation
GR129_RS32220	COG0784	Response regulator, receiver
GR129_RS32225	COG0300	oxidoreductase activity
GR129_RS32255	COG2226	methyltransferase
GR129_RS32340	COG1191	sigma factor activity
GR129_RS32360	COG0542	response to heat
GR129_RS32365	COG1174	glycine betaine transport
GR129_RS32385	COG1556	Lactate utilization protein
GR129_RS32390	COG1139	Iron-sulfur cluster binding protein
GR129_RS32395	COG0247	lactate metabolic process
GR129_RS32410	COG1357	PFAM Pentapeptide repeats (8 copies)
GR129_RS32420	COG1309	transcriptional regulator
GR129_RS32430	COG2706	6-phosphogluconolactonase activity
GR129_RS32470	COG2267	carboxylic ester hydrolase activity
GR129_RS32480	COG1796	DNA polymerase
GR129_RS32480	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GR129_RS32520	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GR129_RS32525	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GR129_RS32530	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GR129_RS32560	COG0435	Glutathione S-transferase
GR129_RS32575	COG2124	cytochrome p450
GR129_RS32610	COG2072	flavoprotein involved in K transport
GR129_RS32615	COG3629	intracellular signal transduction
GR129_RS32625	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
GR129_RS32645	COG0667	Aldo Keto reductase
GR129_RS32670	COG1595	DNA-templated transcription, initiation
GR129_RS32700	COG2890	protein-(glutamine-N5) methyltransferase activity
GR129_RS32720	COG4221	oxidoreductase activity
GR129_RS32810	COG0300	oxidoreductase activity
GR129_RS32830	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GR129_RS32900	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GR129_RS32925	COG1609	Transcriptional regulator
GR129_RS33000	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
GR129_RS33015	COG1335	isochorismatase
GR129_RS33030	COG0671	phosphoesterase, PA-phosphatase related
GR129_RS33035	COG0586	Pfam SNARE associated Golgi protein
GR129_RS33040	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
GR129_RS33055	COG3387	PFAM Glycoside hydrolase 15-related
GR129_RS33060	COG0583	DNA-binding transcription factor activity
GR129_RS33075	COG0590	tRNA wobble adenosine to inosine editing
GR129_RS33095	COG2045	Belongs to the ComB family
GR129_RS33220	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GR129_RS33230	COG3469	chitinase activity
GR129_RS33250	COG0248	Ppx GppA phosphatase
GR129_RS33290	COG2172	sigma factor antagonist activity
GR129_RS33295	COG1366	Belongs to the anti-sigma-factor antagonist family
GR129_RS33300	COG1366	Belongs to the anti-sigma-factor antagonist family
GR129_RS33315	COG1846	Transcriptional regulator
GR129_RS33335	COG1309	transcriptional regulator
GR129_RS33345	COG1028	Short-chain dehydrogenase reductase Sdr
GR129_RS33390	COG0730	response to heat
GR129_RS33400	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GR129_RS33400	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GR129_RS33440	COG2072	flavoprotein involved in K transport
GR129_RS33495	COG0673	inositol 2-dehydrogenase activity
GR129_RS33535	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
GR129_RS33540	COG0318	PFAM AMP-dependent synthetase and ligase
GR129_RS33550	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GR129_RS33555	COG0318	PFAM AMP-dependent synthetase and ligase
GR129_RS33585	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GR129_RS33600	COG0745	RESPONSE REGULATOR receiver
GR129_RS33620	COG5002	protein histidine kinase activity
GR129_RS33635	COG0860	N-Acetylmuramoyl-L-alanine amidase
GR129_RS33635	COG3409	Peptidoglycan-binding domain 1 protein
GR129_RS33645	COG2318	DinB family
GR129_RS33670	COG2197	response regulator
GR129_RS33690	COG0372	Belongs to the citrate synthase family
GR129_RS33720	COG0412	Dienelactone hydrolase
GR129_RS33755	COG0477	Major facilitator Superfamily
GR129_RS33780	COG0513	Belongs to the DEAD box helicase family
GR129_RS33785	COG1278	Cold shock
GR129_RS33840	COG1278	Cold shock
GR129_RS33860	COG0640	Transcriptional regulator
GR129_RS33890	COG0583	DNA-binding transcription factor activity
GR129_RS33910	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GR129_RS33985	COG0596	Alpha beta hydrolase
GR129_RS34015	COG1028	Short-chain dehydrogenase reductase Sdr
GR129_RS34035	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GR129_RS34065	COG0019	diaminopimelate decarboxylase activity
GR129_RS34105	COG0583	DNA-binding transcription factor activity
GR129_RS34115	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GR129_RS34140	COG0477	Major facilitator Superfamily
GR129_RS34145	COG2814	Major facilitator Superfamily
GR129_RS34225	COG2814	Major facilitator Superfamily
GR129_RS34235	COG0151	Belongs to the GarS family
GR129_RS34285	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
GR129_RS34295	COG0515	serine threonine protein kinase
GR129_RS34295	COG3266	domain, Protein
GR129_RS34310	COG0586	Pfam SNARE associated Golgi protein
GR129_RS34335	COG1191	sigma factor activity
GR129_RS34390	COG0009	L-threonylcarbamoyladenylate synthase
GR129_RS34405	COG1366	Belongs to the anti-sigma-factor antagonist family
GR129_RS34410	COG1366	Belongs to the anti-sigma-factor antagonist family
GR129_RS34415	COG2172	sigma factor antagonist activity
GR129_RS34435	COG1295	ribonuclease BN
GR129_RS34435	COG1959	2 iron, 2 sulfur cluster binding
GR129_RS34520	COG0535	radical SAM domain protein
GR129_RS34525	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GR129_RS34530	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GR129_RS34565	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GR129_RS34575	COG1349	DNA-binding transcription factor activity
GR129_RS34585	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GR129_RS34585	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GR129_RS34585	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GR129_RS34650	COG0318	PFAM AMP-dependent synthetase and ligase
GR129_RS34845	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
GR129_RS34890	COG3883	PFAM NLP P60 protein
GR129_RS34890	COG0791	NLP P60 protein
GR129_RS34980	COG0494	nUDIX hydrolase
GR129_RS35080	COG2186	Transcriptional regulator
GR129_RS35125	COG1660	Displays ATPase and GTPase activities
GR129_RS35145	COG1192	Involved in chromosome partitioning