locus-tag	class	description
N8I87_RS00045	COG1595	DNA-templated transcription, initiation
N8I87_RS00100	COG1278	Cold shock
N8I87_RS00145	COG4974	Belongs to the 'phage' integrase family
N8I87_RS00215	COG2226	methyltransferase
N8I87_RS00225	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
N8I87_RS00245	COG1484	DNA-dependent DNA replication
N8I87_RS00250	COG4584	PFAM Integrase catalytic
N8I87_RS00325	COG1518	maintenance of DNA repeat elements
N8I87_RS00340	COG1857	crispr-associated protein
N8I87_RS00400	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
N8I87_RS00415	COG1278	Cold shock
N8I87_RS00425	COG1556	Lactate utilization protein
N8I87_RS00430	COG1139	Iron-sulfur cluster binding protein
N8I87_RS00435	COG0247	lactate metabolic process
N8I87_RS00440	COG1620	l-lactate permease
N8I87_RS00445	COG2186	Transcriptional regulator
N8I87_RS00455	COG0789	Transcriptional regulator
N8I87_RS00475	COG0657	acetylesterase activity
N8I87_RS00485	COG4249	Peptidase C14 caspase catalytic subunit p20
N8I87_RS00485	COG2319	Wd-40 repeat
N8I87_RS00490	COG0657	acetylesterase activity
N8I87_RS00515	COG1250	3-hydroxyacyl-CoA dehydrogenase
N8I87_RS00515	COG1024	Enoyl-CoA hydratase
N8I87_RS00535	COG1024	Enoyl-CoA hydratase
N8I87_RS00585	COG0745	RESPONSE REGULATOR receiver
N8I87_RS00590	COG2205	protein histidine kinase activity
N8I87_RS00640	COG2205	protein histidine kinase activity
N8I87_RS00650	COG1477	protein flavinylation
N8I87_RS00660	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
N8I87_RS00675	COG0516	GMP reductase activity
N8I87_RS00675	COG0517	IMP dehydrogenase activity
N8I87_RS00680	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
N8I87_RS00680	COG3620	sequence-specific DNA binding
N8I87_RS00680	COG0617	tRNA 3'-terminal CCA addition
N8I87_RS00715	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
N8I87_RS00745	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
N8I87_RS00750	COG0569	domain protein
N8I87_RS00760	COG0589	response to stress
N8I87_RS00800	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
N8I87_RS00805	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
N8I87_RS00810	COG0508	dehydrogenase complex catalyzes the overall conversion of
N8I87_RS00810	COG0022	dehydrogenase e1 component
N8I87_RS00815	COG0508	dehydrogenase complex catalyzes the overall conversion of
N8I87_RS00865	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
N8I87_RS00890	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
N8I87_RS00910	COG3629	intracellular signal transduction
N8I87_RS00920	COG2124	cytochrome p450
N8I87_RS00930	COG0604	alcohol dehydrogenase
N8I87_RS00975	COG0604	alcohol dehydrogenase
N8I87_RS00975	COG3321	synthase
N8I87_RS01075	COG0586	Pfam SNARE associated Golgi protein
N8I87_RS01080	COG0438	transferase activity, transferring glycosyl groups
N8I87_RS01085	COG1968	undecaprenyl-diphosphatase activity
N8I87_RS01095	COG0745	RESPONSE REGULATOR receiver
N8I87_RS01100	COG5002	protein histidine kinase activity
N8I87_RS01120	COG2217	Heavy metal translocating P-type atpase
N8I87_RS01125	COG1937	Protein conserved in bacteria
N8I87_RS01130	COG2132	Multicopper oxidase
N8I87_RS01175	COG1140	nitrate reductase beta subunit
N8I87_RS01185	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
N8I87_RS01225	COG2151	metal-sulfur cluster biosynthetic enzyme
N8I87_RS01235	COG1366	Belongs to the anti-sigma-factor antagonist family
N8I87_RS01245	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
N8I87_RS01295	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
N8I87_RS01310	COG4716	Myosin-crossreactive antigen
N8I87_RS01380	COG4214	carbohydrate transport
N8I87_RS01385	COG4213	ABC transporter substrate-binding protein
N8I87_RS01395	COG0252	asparaginase activity
N8I87_RS01405	COG0431	NADPH-dependent FMN reductase
N8I87_RS01415	COG0277	FAD linked oxidase domain protein
N8I87_RS01440	COG3261	NADH dehydrogenase
N8I87_RS01440	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
N8I87_RS01445	COG0651	ATP synthesis coupled electron transport
N8I87_RS01455	COG0650	Formate hydrogenlyase subunit 4
N8I87_RS01465	COG3260	NADH ubiquinone oxidoreductase 20
N8I87_RS01495	COG0659	secondary active sulfate transmembrane transporter activity
N8I87_RS01505	COG2824	Alkylphosphonate utilization operon protein PhnA
N8I87_RS01515	COG0205	6-phosphofructokinase activity
N8I87_RS01520	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N8I87_RS01555	COG2207	Transcriptional regulator
N8I87_RS01575	COG0366	Alpha amylase catalytic
N8I87_RS01590	COG1653	transport
N8I87_RS01595	COG1609	Transcriptional regulator
N8I87_RS01605	COG2205	protein histidine kinase activity
N8I87_RS01610	COG0745	RESPONSE REGULATOR receiver
N8I87_RS01615	COG0477	Major facilitator Superfamily
N8I87_RS01620	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N8I87_RS01645	COG1309	transcriptional regulator
N8I87_RS01650	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
N8I87_RS01660	COG0640	Transcriptional regulator
N8I87_RS01665	COG2226	methyltransferase
N8I87_RS01705	COG3511	phospholipase C
N8I87_RS01720	COG0596	Alpha beta hydrolase
N8I87_RS01770	COG0477	Major facilitator Superfamily
N8I87_RS01775	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
N8I87_RS01785	COG2205	protein histidine kinase activity
N8I87_RS01815	COG0022	dehydrogenase e1 component
N8I87_RS01820	COG1012	belongs to the aldehyde dehydrogenase family
N8I87_RS01830	COG1309	transcriptional regulator
N8I87_RS01840	COG2072	flavoprotein involved in K transport
N8I87_RS01845	COG2267	carboxylic ester hydrolase activity
N8I87_RS01860	COG3795	YCII-related domain
N8I87_RS01870	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
N8I87_RS01900	COG2124	cytochrome p450
N8I87_RS01930	COG2814	Major facilitator Superfamily
N8I87_RS01940	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
N8I87_RS01970	COG1846	Transcriptional regulator
N8I87_RS01995	COG0745	RESPONSE REGULATOR receiver
N8I87_RS02000	COG2205	protein histidine kinase activity
N8I87_RS02005	COG1595	DNA-templated transcription, initiation
N8I87_RS02010	COG0655	NAD(P)H dehydrogenase (quinone) activity
N8I87_RS02025	COG1063	alcohol dehydrogenase
N8I87_RS02030	COG0395	ABC-type sugar transport system, permease component
N8I87_RS02035	COG1175	transmembrane transport
N8I87_RS02045	COG1349	DNA-binding transcription factor activity
N8I87_RS02085	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N8I87_RS02130	COG0702	epimerase
N8I87_RS02150	COG2084	Dehydrogenase
N8I87_RS02160	COG2124	cytochrome p450
N8I87_RS02185	COG0583	DNA-binding transcription factor activity
N8I87_RS02255	COG2226	methyltransferase
N8I87_RS02285	COG0667	Aldo Keto reductase
N8I87_RS02330	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
N8I87_RS02380	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N8I87_RS02390	COG2130	NADP-dependent
N8I87_RS02405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N8I87_RS02410	COG3850	Histidine kinase
N8I87_RS02415	COG2197	response regulator
N8I87_RS02425	COG0539	negative regulation of cytoplasmic translation
N8I87_RS02455	COG1140	nitrate reductase beta subunit
N8I87_RS02475	COG1017	nitric oxide dioxygenase activity
N8I87_RS02475	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
N8I87_RS02510	COG2132	Multicopper oxidase
N8I87_RS02515	COG0535	radical SAM domain protein
N8I87_RS02525	COG1140	nitrate reductase beta subunit
N8I87_RS02545	COG0303	'Molybdopterin
N8I87_RS02550	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
N8I87_RS02560	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
N8I87_RS02560	COG1918	ferrous iron import across plasma membrane
N8I87_RS02570	COG1045	serine acetyltransferase
N8I87_RS02605	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
N8I87_RS02635	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
N8I87_RS02635	COG1017	nitric oxide dioxygenase activity
N8I87_RS02640	COG1960	acyl-CoA dehydrogenase activity
N8I87_RS02645	COG1804	L-carnitine dehydratase bile acid-inducible protein F
N8I87_RS02650	COG0583	DNA-binding transcription factor activity
N8I87_RS02665	COG1028	Short-chain dehydrogenase reductase Sdr
N8I87_RS02700	COG0277	FAD linked oxidase domain protein
N8I87_RS02755	COG0346	lactoylglutathione lyase activity
N8I87_RS02780	COG2318	DinB family
N8I87_RS02800	COG0697	spore germination
N8I87_RS02845	COG0515	serine threonine protein kinase
N8I87_RS02850	COG1132	(ABC) transporter
N8I87_RS02870	COG0598	Magnesium transport protein CorA
N8I87_RS02875	COG3387	PFAM Glycoside hydrolase 15-related
N8I87_RS02885	COG1271	oxidase subunit
N8I87_RS02890	COG1028	Short-chain dehydrogenase reductase Sdr
N8I87_RS02900	COG0730	response to heat
N8I87_RS02905	COG0730	response to heat
N8I87_RS02910	COG3594	Acyltransferase
N8I87_RS02965	COG0701	Predicted permease
N8I87_RS03065	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
N8I87_RS03095	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
N8I87_RS03100	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
N8I87_RS03120	COG4176	ABC-type proline glycine betaine transport system permease component
N8I87_RS03125	COG4175	Glycine betaine
N8I87_RS03125	COG0517	IMP dehydrogenase activity
N8I87_RS03130	COG1012	belongs to the aldehyde dehydrogenase family
N8I87_RS03145	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
N8I87_RS03155	COG4638	Rieske (2fe-2S)
N8I87_RS03210	COG1796	DNA polymerase
N8I87_RS03210	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
N8I87_RS03240	COG1063	alcohol dehydrogenase
N8I87_RS03260	COG0549	Belongs to the carbamate kinase family
N8I87_RS03265	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
N8I87_RS03275	COG0531	amino acid
N8I87_RS03300	COG0318	PFAM AMP-dependent synthetase and ligase
N8I87_RS03365	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
N8I87_RS03385	COG3469	chitinase activity
N8I87_RS03550	COG0309	Hydrogenase expression formation protein (HypE)
N8I87_RS03560	COG0298	carbon dioxide binding
N8I87_RS03565	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
N8I87_RS03570	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
N8I87_RS03575	COG0375	protein maturation
N8I87_RS03605	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
N8I87_RS03615	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
N8I87_RS03615	COG1024	Enoyl-CoA hydratase
N8I87_RS03640	COG0009	L-threonylcarbamoyladenylate synthase
N8I87_RS03690	COG3739	integral membrane protein
N8I87_RS03720	COG2755	lipolytic protein G-D-S-L family
N8I87_RS03725	COG1063	alcohol dehydrogenase
N8I87_RS03745	COG0181	hydroxymethylbilane synthase activity
N8I87_RS03765	COG1846	Transcriptional regulator
N8I87_RS03805	COG0366	Alpha amylase catalytic
N8I87_RS03815	COG3281	Trehalose synthase
N8I87_RS03820	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
N8I87_RS03825	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
N8I87_RS03845	COG1252	NADH dehydrogenase
N8I87_RS03920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N8I87_RS03965	COG2340	Cysteine-rich secretory protein family
N8I87_RS03990	COG0515	serine threonine protein kinase
N8I87_RS03990	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
N8I87_RS04005	COG3647	Membrane
N8I87_RS04015	COG0667	Aldo Keto reductase
N8I87_RS04035	COG2304	oxidoreductase activity
N8I87_RS04040	COG0328	RNA-DNA hybrid ribonuclease activity
N8I87_RS04060	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
N8I87_RS04075	COG0596	Alpha beta hydrolase
N8I87_RS04080	COG1396	sequence-specific DNA binding
N8I87_RS04085	COG2318	DinB family
N8I87_RS04090	COG1191	sigma factor activity
N8I87_RS04120	COG1131	(ABC) transporter
N8I87_RS04120	COG1716	ATPase activity
N8I87_RS04120	COG0842	Transport permease protein
N8I87_RS04140	COG0667	Aldo Keto reductase
N8I87_RS04145	COG0583	DNA-binding transcription factor activity
N8I87_RS04155	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
N8I87_RS04175	COG0667	Aldo Keto reductase
N8I87_RS04185	COG1012	belongs to the aldehyde dehydrogenase family
N8I87_RS04190	COG4941	Belongs to the sigma-70 factor family
N8I87_RS04215	COG0531	amino acid
N8I87_RS04220	COG1940	carbohydrate kinase activity
N8I87_RS04225	COG3250	beta-galactosidase activity
N8I87_RS04265	COG0367	asparagine synthase
N8I87_RS04280	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
N8I87_RS04280	COG3320	Male sterility
N8I87_RS04285	COG0604	alcohol dehydrogenase
N8I87_RS04285	COG3321	synthase
N8I87_RS04290	COG0318	PFAM AMP-dependent synthetase and ligase
N8I87_RS04305	COG0673	inositol 2-dehydrogenase activity
N8I87_RS04310	COG3511	phospholipase C
N8I87_RS04345	COG1672	PFAM Archaeal ATPase
N8I87_RS04345	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
N8I87_RS04375	COG1024	Enoyl-CoA hydratase
N8I87_RS04400	COG0318	PFAM AMP-dependent synthetase and ligase
N8I87_RS04415	COG2070	2-Nitropropane dioxygenase
N8I87_RS04430	COG0515	serine threonine protein kinase
N8I87_RS04440	COG1960	acyl-CoA dehydrogenase activity
N8I87_RS04485	COG4191	Histidine kinase
N8I87_RS04490	COG2376	Dihydroxyacetone kinase
N8I87_RS04495	COG1461	Dihydroxyacetone kinase
N8I87_RS04525	COG0446	pyridine nucleotide-disulphide oxidoreductase
N8I87_RS04525	COG1902	pentaerythritol trinitrate reductase activity
N8I87_RS04545	COG2890	protein-(glutamine-N5) methyltransferase activity
N8I87_RS04565	COG3458	cephalosporin-C deacetylase activity
N8I87_RS04570	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
N8I87_RS04575	COG2188	Transcriptional regulator
N8I87_RS04580	COG2226	methyltransferase
N8I87_RS04595	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
N8I87_RS04615	COG2066	Belongs to the glutaminase family
N8I87_RS04630	COG1113	amino acid transport
N8I87_RS04635	COG2186	Transcriptional regulator
N8I87_RS04640	COG1968	undecaprenyl-diphosphatase activity
N8I87_RS04645	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
N8I87_RS04650	COG1993	acr, cog1993
N8I87_RS04695	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
N8I87_RS04705	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
N8I87_RS04730	COG2340	Cysteine-rich secretory protein family
N8I87_RS04765	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
N8I87_RS04800	COG1028	Short-chain dehydrogenase reductase Sdr
N8I87_RS04825	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
N8I87_RS04830	COG1215	transferase activity, transferring glycosyl groups
N8I87_RS04865	COG1349	DNA-binding transcription factor activity
N8I87_RS04890	COG0577	efflux transmembrane transporter activity
N8I87_RS04925	COG1940	carbohydrate kinase activity
N8I87_RS04975	COG4974	Belongs to the 'phage' integrase family
N8I87_RS04990	COG2813	Specifically methylates the guanine in position
N8I87_RS05000	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
N8I87_RS05005	COG1349	DNA-binding transcription factor activity
N8I87_RS05050	COG2197	response regulator
N8I87_RS05055	COG4585	Histidine kinase
N8I87_RS05080	COG0445	tRNA wobble uridine modification
N8I87_RS05095	COG1660	Displays ATPase and GTPase activities
N8I87_RS05135	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
N8I87_RS05140	COG2086	electron transfer activity
N8I87_RS05155	COG0204	Acyl-transferase
N8I87_RS05185	COG0584	glycerophosphoryl diester phosphodiesterase
N8I87_RS05210	COG1846	Transcriptional regulator
N8I87_RS05230	COG0671	phosphoesterase, PA-phosphatase related
N8I87_RS05240	COG1309	transcriptional regulator
N8I87_RS05255	COG0640	Transcriptional regulator
N8I87_RS05260	COG1902	pentaerythritol trinitrate reductase activity
N8I87_RS05275	COG1960	acyl-CoA dehydrogenase activity
N8I87_RS05295	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
N8I87_RS05300	COG2971	BadF BadG BcrA BcrD
N8I87_RS05310	COG2706	6-phosphogluconolactonase activity
N8I87_RS05325	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
N8I87_RS05330	COG0477	Major facilitator Superfamily
N8I87_RS05375	COG0714	Associated with various cellular activities
N8I87_RS05395	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
N8I87_RS05410	COG0432	Pfam Uncharacterised protein family UPF0047
N8I87_RS05415	COG1064	alcohol dehydrogenase
N8I87_RS05445	COG0842	Transport permease protein
N8I87_RS05445	COG1129	ABC transporter
N8I87_RS05470	COG1309	transcriptional regulator
N8I87_RS05480	COG2818	Glycosylase
N8I87_RS05515	COG2072	flavoprotein involved in K transport
N8I87_RS05520	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
N8I87_RS05525	COG1132	(ABC) transporter
N8I87_RS05555	COG1132	(ABC) transporter
N8I87_RS05560	COG1132	(ABC) transporter
N8I87_RS05570	COG0254	rRNA binding
N8I87_RS05585	COG1946	Acyl-CoA thioesterase
N8I87_RS05595	COG2018	Roadblock/LC7 domain
N8I87_RS05645	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
N8I87_RS05680	COG2267	carboxylic ester hydrolase activity
N8I87_RS05685	COG1051	belongs to the nudix hydrolase family
N8I87_RS05710	COG1012	belongs to the aldehyde dehydrogenase family
N8I87_RS05715	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
N8I87_RS05720	COG1012	belongs to the aldehyde dehydrogenase family
N8I87_RS05770	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
N8I87_RS05795	COG1960	acyl-CoA dehydrogenase activity
N8I87_RS05800	COG1960	acyl-CoA dehydrogenase activity
N8I87_RS05815	COG0492	ferredoxin-NADP+ reductase activity
N8I87_RS05820	COG1793	dna ligase
N8I87_RS05830	COG1012	belongs to the aldehyde dehydrogenase family
N8I87_RS05840	COG3424	synthase
N8I87_RS05845	COG2124	cytochrome p450
N8I87_RS05855	COG1960	acyl-CoA dehydrogenase activity
N8I87_RS05865	COG0242	peptide deformylase activity
N8I87_RS05870	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
N8I87_RS05875	COG3442	glutamine amidotransferase
N8I87_RS05880	COG0205	6-phosphofructokinase activity
N8I87_RS05900	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N8I87_RS05915	COG1522	sequence-specific DNA binding
N8I87_RS05920	COG1834	amidinotransferase
N8I87_RS05925	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
N8I87_RS05940	COG0204	Acyl-transferase
N8I87_RS05950	COG0829	nickel cation binding
N8I87_RS05955	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
N8I87_RS05960	COG0830	nickel cation binding
N8I87_RS05965	COG0804	urea catabolic process
N8I87_RS05970	COG0832	Belongs to the urease beta subunit family
N8I87_RS05975	COG0831	urea catabolic process
N8I87_RS05980	COG1309	transcriptional regulator
N8I87_RS05995	COG0740	serine-type endopeptidase activity
N8I87_RS06010	COG1280	lysine exporter protein (LysE YggA)
N8I87_RS06015	COG0583	DNA-binding transcription factor activity
N8I87_RS06035	COG0156	8-amino-7-oxononanoate synthase activity
N8I87_RS06045	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
N8I87_RS06050	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
N8I87_RS06055	COG2226	methyltransferase
N8I87_RS06060	COG1136	(ABC) transporter
N8I87_RS06060	COG0577	efflux transmembrane transporter activity
N8I87_RS06065	COG0577	efflux transmembrane transporter activity
N8I87_RS06065	COG1136	(ABC) transporter
N8I87_RS06100	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
N8I87_RS06105	COG3663	DNA glycosylase
N8I87_RS06125	COG4585	Histidine kinase
N8I87_RS06130	COG2197	response regulator
N8I87_RS06135	COG1940	carbohydrate kinase activity
N8I87_RS06140	COG2188	Transcriptional regulator
N8I87_RS06145	COG1595	DNA-templated transcription, initiation
N8I87_RS06155	COG2267	carboxylic ester hydrolase activity
N8I87_RS06165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N8I87_RS06190	COG0626	cystathionine gamma-synthase activity
N8I87_RS06215	COG1522	sequence-specific DNA binding
N8I87_RS06225	COG0420	3'-5' exonuclease activity
N8I87_RS06240	COG1739	Uncharacterized protein family UPF0029
N8I87_RS06255	COG1832	CoA-binding protein
N8I87_RS06260	COG0531	amino acid
N8I87_RS06265	COG0640	Transcriptional regulator
N8I87_RS06290	COG0110	maltose O-acetyltransferase activity
N8I87_RS06315	COG1819	glycosyl
N8I87_RS06320	COG0596	Alpha beta hydrolase
N8I87_RS06330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N8I87_RS06330	COG3321	synthase
N8I87_RS06370	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
N8I87_RS06385	COG0183	Belongs to the thiolase family
N8I87_RS06410	COG1968	undecaprenyl-diphosphatase activity
N8I87_RS06435	COG0815	Transfers the fatty acyl group on membrane lipoproteins
N8I87_RS06445	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N8I87_RS06465	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
N8I87_RS06515	COG0697	spore germination
N8I87_RS06550	COG1695	Transcriptional regulator
N8I87_RS06560	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
N8I87_RS06565	COG2326	polyphosphate kinase activity
N8I87_RS06595	COG0384	phenazine biosynthesis protein PhzF
N8I87_RS06665	COG0725	ABC transporter, periplasmic molybdate-binding protein
N8I87_RS06690	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
N8I87_RS06690	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
N8I87_RS06700	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
N8I87_RS06740	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
N8I87_RS06770	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
N8I87_RS06780	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
N8I87_RS06810	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
N8I87_RS06815	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
N8I87_RS06835	COG2018	Roadblock/LC7 domain
N8I87_RS06870	COG2814	Major facilitator Superfamily
N8I87_RS06875	COG4336	lyase activity
N8I87_RS06880	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
N8I87_RS06890	COG1984	allophanate hydrolase subunit 2
N8I87_RS06895	COG2755	lipolytic protein G-D-S-L family
N8I87_RS06900	COG0438	transferase activity, transferring glycosyl groups
N8I87_RS06935	COG2364	Membrane
N8I87_RS06945	COG2270	Major facilitator Superfamily
N8I87_RS06960	COG1216	Glycosyl transferase, family 2
N8I87_RS06985	COG1960	acyl-CoA dehydrogenase activity
N8I87_RS07045	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
N8I87_RS07050	COG0140	phosphoribosyl-ATP diphosphatase activity
N8I87_RS07055	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
N8I87_RS07060	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
N8I87_RS07060	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
N8I87_RS07065	COG3201	nicotinamide mononucleotide transporter
N8I87_RS07075	COG1595	DNA-templated transcription, initiation
N8I87_RS07080	COG0702	epimerase
N8I87_RS07085	COG1846	Transcriptional regulator
N8I87_RS07085	COG1940	carbohydrate kinase activity
N8I87_RS07090	COG2223	nitrite transmembrane transporter activity
N8I87_RS07125	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
N8I87_RS07155	COG3842	ATPase activity
N8I87_RS07175	COG2188	Transcriptional regulator
N8I87_RS07190	COG0531	amino acid
N8I87_RS07205	COG2390	Transcriptional regulator
N8I87_RS07210	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
N8I87_RS07215	COG2409	Drug exporters of the RND superfamily
N8I87_RS07225	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
N8I87_RS07240	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
N8I87_RS07255	COG0194	GDP metabolic process
N8I87_RS07265	COG0284	orotidine-5'-phosphate decarboxylase activity
N8I87_RS07270	COG0167	dihydroorotate dehydrogenase activity
N8I87_RS07275	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
N8I87_RS07280	COG0505	Belongs to the CarA family
N8I87_RS07290	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
N8I87_RS07295	COG0540	Belongs to the ATCase OTCase family
N8I87_RS07300	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
N8I87_RS07310	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
N8I87_RS07315	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
N8I87_RS07320	COG0006	proline dipeptidase activity
N8I87_RS07330	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
N8I87_RS07335	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
N8I87_RS07340	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
N8I87_RS07345	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
N8I87_RS07355	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
N8I87_RS07360	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
N8I87_RS07375	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
N8I87_RS07390	COG1131	(ABC) transporter
N8I87_RS07400	COG4585	Histidine kinase
N8I87_RS07405	COG2197	response regulator
N8I87_RS07410	COG0124	histidyl-tRNA synthetase
N8I87_RS07420	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
N8I87_RS07425	COG1196	nuclear chromosome segregation
N8I87_RS07435	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
N8I87_RS07440	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
N8I87_RS07445	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
N8I87_RS07450	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
N8I87_RS07460	COG2255	four-way junction helicase activity
N8I87_RS07465	COG0632	four-way junction helicase activity
N8I87_RS07470	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
N8I87_RS07475	COG0217	transcriptional regulatory protein
N8I87_RS07480	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
N8I87_RS07485	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
N8I87_RS07495	COG0438	transferase activity, transferring glycosyl groups
N8I87_RS07500	COG1560	Kdo2-lipid A biosynthetic process
N8I87_RS07505	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
N8I87_RS07525	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
N8I87_RS07540	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
N8I87_RS07620	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
N8I87_RS07620	COG0512	Glutamine amidotransferase of anthranilate synthase
N8I87_RS07675	COG0494	nUDIX hydrolase
N8I87_RS07680	COG2801	Transposase and inactivated derivatives
N8I87_RS07680	COG3415	Transposase
N8I87_RS07690	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
N8I87_RS07690	COG1648	precorrin-2 dehydrogenase activity
N8I87_RS07710	COG1464	Belongs to the NlpA lipoprotein family
N8I87_RS07715	COG2011	ABC-type metal ion transport system permease component
N8I87_RS07720	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
N8I87_RS07755	COG0204	Acyl-transferase
N8I87_RS07755	COG0318	PFAM AMP-dependent synthetase and ligase
N8I87_RS07760	COG0477	Major facilitator Superfamily
N8I87_RS07775	COG0165	Argininosuccinate lyase
N8I87_RS07780	COG0137	argininosuccinate synthase activity
N8I87_RS07800	COG2205	protein histidine kinase activity
N8I87_RS07805	COG0745	RESPONSE REGULATOR receiver
N8I87_RS07810	COG1017	nitric oxide dioxygenase activity
N8I87_RS07810	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
N8I87_RS07835	COG1438	arginine binding
N8I87_RS07840	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
N8I87_RS07845	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
N8I87_RS07850	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
N8I87_RS07855	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
N8I87_RS07920	COG1649	PFAM Uncharacterised BCR, COG1649
N8I87_RS07950	COG0072	phenylalanine-tRNA ligase activity
N8I87_RS07950	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N8I87_RS07955	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
N8I87_RS07960	COG5002	protein histidine kinase activity
N8I87_RS07965	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
N8I87_RS07970	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
N8I87_RS07975	COG0291	Belongs to the bacterial ribosomal protein bL35 family
N8I87_RS07980	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
N8I87_RS08020	COG1028	Short-chain dehydrogenase reductase Sdr
N8I87_RS08025	COG1012	belongs to the aldehyde dehydrogenase family
N8I87_RS08030	COG0174	glutamine synthetase
N8I87_RS08035	COG2186	Transcriptional regulator
N8I87_RS08040	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
N8I87_RS08055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N8I87_RS08070	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
N8I87_RS08080	COG0564	pseudouridine synthase activity
N8I87_RS08115	COG0805	protein transport
N8I87_RS08120	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
N8I87_RS08155	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
N8I87_RS08165	COG1609	Transcriptional regulator
N8I87_RS08170	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
N8I87_RS08175	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
N8I87_RS08190	COG4122	O-methyltransferase activity
N8I87_RS08195	COG1222	aaa ATPase
N8I87_RS08215	COG0517	IMP dehydrogenase activity
N8I87_RS08215	COG1994	Peptidase M50
N8I87_RS08225	COG2197	response regulator
N8I87_RS08230	COG4533	DNA binding
N8I87_RS08235	COG0747	negative chemotaxis
N8I87_RS08245	COG1410	methionine synthase
N8I87_RS08245	COG0646	methionine synthase
N8I87_RS08250	COG1414	Transcriptional regulator
N8I87_RS08255	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
N8I87_RS08260	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
N8I87_RS08265	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
N8I87_RS08270	COG2186	Transcriptional regulator
N8I87_RS08280	COG1404	Belongs to the peptidase S8 family
N8I87_RS08290	COG0215	cysteine-tRNA ligase activity
N8I87_RS08310	COG0598	Magnesium transport protein CorA
N8I87_RS08320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N8I87_RS08325	COG0667	Aldo Keto reductase
N8I87_RS08375	COG0308	aminopeptidase N
N8I87_RS08380	COG3012	SEC-C Motif Domain Protein
N8I87_RS08385	COG2186	Transcriptional regulator
N8I87_RS08390	COG3265	gluconokinase activity
N8I87_RS08420	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
N8I87_RS08425	COG2149	membrane
N8I87_RS08450	COG1960	acyl-CoA dehydrogenase activity
N8I87_RS08460	COG1309	transcriptional regulator
N8I87_RS08465	COG0318	PFAM AMP-dependent synthetase and ligase
N8I87_RS08475	COG3876	Protein conserved in bacteria
N8I87_RS08520	COG1960	acyl-CoA dehydrogenase activity
N8I87_RS08530	COG0640	Transcriptional regulator
N8I87_RS08555	COG0243	molybdopterin cofactor binding
N8I87_RS08560	COG1309	transcriptional regulator
N8I87_RS08570	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
N8I87_RS08575	COG2188	Transcriptional regulator
N8I87_RS08615	COG1595	DNA-templated transcription, initiation
N8I87_RS08640	COG2755	lipolytic protein G-D-S-L family
N8I87_RS08660	COG0726	polysaccharide deacetylase
N8I87_RS08660	COG1649	PFAM Uncharacterised BCR, COG1649
N8I87_RS08685	COG1725	Transcriptional regulator
N8I87_RS08735	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
N8I87_RS08740	COG0587	DNA-directed DNA polymerase activity
N8I87_RS08750	COG0330	HflC and HflK could
N8I87_RS08765	COG1799	cell septum assembly
N8I87_RS08770	COG1960	acyl-CoA dehydrogenase activity
N8I87_RS08775	COG0477	Major facilitator Superfamily
N8I87_RS08785	COG0671	phosphoesterase, PA-phosphatase related
N8I87_RS08825	COG3583	domain protein
N8I87_RS08840	COG1160	GTP binding
N8I87_RS08850	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
N8I87_RS08880	COG3541	Predicted nucleotidyltransferase
N8I87_RS08895	COG1187	pseudouridine synthase activity
N8I87_RS08900	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
N8I87_RS08905	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
N8I87_RS08920	COG0686	Belongs to the AlaDH PNT family
N8I87_RS08930	COG0494	nUDIX hydrolase
N8I87_RS08935	COG0504	CTP synthase activity
N8I87_RS08940	COG3387	PFAM Glycoside hydrolase 15-related
N8I87_RS08945	COG0277	FAD linked oxidase domain protein
N8I87_RS08955	COG0297	glycogen (starch) synthase activity
N8I87_RS08965	COG0497	DNA recombination
N8I87_RS08970	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
N8I87_RS08990	COG1120	ATPase activity
N8I87_RS08995	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N8I87_RS09000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N8I87_RS09005	COG0647	UMP catabolic process
N8I87_RS09040	COG2094	Belongs to the DNA glycosylase MPG family
N8I87_RS09050	COG1881	PFAM PEBP family protein
N8I87_RS09070	COG1119	ATPase activity
N8I87_RS09085	COG2197	response regulator
N8I87_RS09090	COG4585	Histidine kinase
N8I87_RS09095	COG4221	oxidoreductase activity
N8I87_RS09100	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
N8I87_RS09110	COG0842	Transport permease protein
N8I87_RS09110	COG1131	(ABC) transporter
N8I87_RS09110	COG1716	ATPase activity
N8I87_RS09120	COG3830	Belongs to the UPF0237 family
N8I87_RS09120	COG0560	Phosphoserine phosphatase
N8I87_RS09125	COG0588	phosphoglycerate mutase activity
N8I87_RS09145	COG2186	Transcriptional regulator
N8I87_RS09160	COG1028	Short-chain dehydrogenase reductase Sdr
N8I87_RS09175	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
N8I87_RS09195	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
N8I87_RS09200	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N8I87_RS09235	COG1063	alcohol dehydrogenase
N8I87_RS09255	COG0300	oxidoreductase activity
N8I87_RS09260	COG4689	acetoacetate decarboxylase
N8I87_RS09265	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
N8I87_RS09280	COG3387	PFAM Glycoside hydrolase 15-related
N8I87_RS09320	COG1024	Enoyl-CoA hydratase
N8I87_RS09330	COG0488	(ABC) transporter
N8I87_RS09350	COG0235	Class ii aldolase
N8I87_RS09370	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
N8I87_RS09375	COG1492	cobalamin metabolic process
N8I87_RS09395	COG1797	cobyrinic acid a,c-diamide synthase activity
N8I87_RS09430	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
N8I87_RS09455	COG0765	amino acid transport
N8I87_RS09460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N8I87_RS09465	COG0456	acetyltransferase
N8I87_RS09470	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
N8I87_RS09475	COG1917	Cupin 2, conserved barrel domain protein
N8I87_RS09480	COG5285	phytanoyl-CoA dioxygenase
N8I87_RS09485	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
N8I87_RS09530	COG2197	response regulator
N8I87_RS09540	COG1595	DNA-templated transcription, initiation
N8I87_RS09550	COG5297	Belongs to the glycosyl hydrolase family 6
N8I87_RS09565	COG4677	pectinesterase activity
N8I87_RS09585	COG1802	Transcriptional regulator
N8I87_RS09610	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N8I87_RS09615	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
N8I87_RS09620	COG1349	DNA-binding transcription factor activity
N8I87_RS09635	COG0395	ABC-type sugar transport system, permease component
N8I87_RS09710	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N8I87_RS09720	COG1595	DNA-templated transcription, initiation
N8I87_RS09730	COG2171	N-acyltransferase activity
N8I87_RS09735	COG3226	Transcriptional regulator
N8I87_RS09740	COG2076	Multidrug Resistance protein
N8I87_RS09755	COG2151	metal-sulfur cluster biosynthetic enzyme
N8I87_RS09760	COG0822	iron-sulfur transferase activity
N8I87_RS09765	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
N8I87_RS09770	COG0396	ATPase activity
N8I87_RS09780	COG0719	Fe-S assembly protein
N8I87_RS09795	COG2746	aminoglycoside 3-N-acetyltransferase activity
N8I87_RS09800	COG1131	(ABC) transporter
N8I87_RS09810	COG1612	heme a metabolic process
N8I87_RS09830	COG0109	protoheme IX farnesyltransferase activity
N8I87_RS09840	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
N8I87_RS09855	COG0363	glucosamine-6-phosphate deaminase activity
N8I87_RS09860	COG0395	ABC-type sugar transport system, permease component
N8I87_RS09865	COG1175	transmembrane transport
N8I87_RS09870	COG1653	transport
N8I87_RS09875	COG0366	Alpha amylase catalytic
N8I87_RS09885	COG1695	Transcriptional regulator
N8I87_RS09890	COG1136	(ABC) transporter
N8I87_RS09900	COG0166	Belongs to the GPI family
N8I87_RS09915	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
N8I87_RS09920	COG0149	triose-phosphate isomerase activity
N8I87_RS09925	COG0126	phosphoglycerate kinase activity
N8I87_RS09930	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
N8I87_RS09940	COG1481	regulation of sporulation
N8I87_RS09950	COG1660	Displays ATPase and GTPase activities
N8I87_RS09955	COG0322	excinuclease ABC activity
N8I87_RS09970	COG1609	Transcriptional regulator
N8I87_RS09980	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
N8I87_RS09990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N8I87_RS09995	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
N8I87_RS10000	COG1619	proteins homologs of microcin C7 resistance protein MccF
N8I87_RS10005	COG0477	Major facilitator Superfamily
N8I87_RS10010	COG0387	Pfam Sodium calcium exchanger
N8I87_RS10035	COG0556	nucleotide-excision repair
N8I87_RS10045	COG0584	glycerophosphoryl diester phosphodiesterase
N8I87_RS10050	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
N8I87_RS10060	COG2313	pseudouridylate synthase activity
N8I87_RS10065	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
N8I87_RS10065	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
N8I87_RS10075	COG2226	methyltransferase
N8I87_RS10080	COG0598	Magnesium transport protein CorA
N8I87_RS10110	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
N8I87_RS10115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N8I87_RS10155	COG2124	cytochrome p450
N8I87_RS10160	COG0402	S-adenosylhomocysteine deaminase activity
N8I87_RS10235	COG2226	methyltransferase
N8I87_RS10255	COG0237	dephospho-CoA kinase activity
N8I87_RS10265	COG0539	negative regulation of cytoplasmic translation
N8I87_RS10315	COG2050	protein possibly involved in aromatic compounds catabolism
N8I87_RS10365	COG0737	Belongs to the 5'-nucleotidase family
N8I87_RS10395	COG1605	Chorismate mutase
N8I87_RS10395	COG0287	Prephenate dehydrogenase
N8I87_RS10405	COG1028	Short-chain dehydrogenase reductase Sdr
N8I87_RS10410	COG1028	Short-chain dehydrogenase reductase Sdr
N8I87_RS10415	COG1024	Enoyl-CoA hydratase
N8I87_RS10440	COG0183	Belongs to the thiolase family
N8I87_RS10445	COG1309	transcriptional regulator
N8I87_RS10450	COG1028	Short-chain dehydrogenase reductase Sdr
N8I87_RS10455	COG1960	acyl-CoA dehydrogenase activity
N8I87_RS10465	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
N8I87_RS10470	COG2304	oxidoreductase activity
N8I87_RS10490	COG1215	transferase activity, transferring glycosyl groups
N8I87_RS10510	COG0067	glutamate synthase
N8I87_RS10510	COG0069	glutamate synthase activity
N8I87_RS10510	COG0070	glutamate synthase
N8I87_RS10540	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N8I87_RS10545	COG1804	L-carnitine dehydratase bile acid-inducible protein F
N8I87_RS10550	COG2301	Belongs to the HpcH HpaI aldolase family
N8I87_RS10555	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
N8I87_RS10565	COG0159	tryptophan synthase activity
N8I87_RS10570	COG0133	tryptophan synthase activity
N8I87_RS10575	COG0134	indole-3-glycerol-phosphate synthase activity
N8I87_RS10600	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
N8I87_RS10625	COG0107	imidazoleglycerol-phosphate synthase activity
N8I87_RS10630	COG0251	oxidation-reduction process
N8I87_RS10635	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
N8I87_RS10640	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
N8I87_RS10650	COG0131	Imidazoleglycerol-phosphate dehydratase
N8I87_RS10655	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
N8I87_RS10660	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
N8I87_RS10710	COG1432	Conserved Protein
N8I87_RS10720	COG0587	DNA-directed DNA polymerase activity
N8I87_RS10780	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
N8I87_RS10790	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
N8I87_RS10800	COG3599	regulation of cell shape
N8I87_RS10810	COG1799	cell septum assembly
N8I87_RS10820	COG1496	oxidoreductase activity
N8I87_RS10825	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
N8I87_RS10830	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
N8I87_RS10835	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
N8I87_RS10845	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
N8I87_RS10850	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
N8I87_RS10860	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
N8I87_RS10875	COG0275	rRNA processing
N8I87_RS10885	COG0714	Associated with various cellular activities
N8I87_RS10905	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
N8I87_RS10915	COG1126	abc transporter atp-binding protein
N8I87_RS10925	COG1309	transcriptional regulator
N8I87_RS10950	COG0352	thiamine-phosphate diphosphorylase activity
N8I87_RS10965	COG2022	thiamine diphosphate biosynthetic process
N8I87_RS10965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N8I87_RS10975	COG2022	thiamine diphosphate biosynthetic process
N8I87_RS10980	COG0515	serine threonine protein kinase
N8I87_RS10980	COG2815	serine threonine protein kinase
N8I87_RS10985	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
N8I87_RS10995	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
N8I87_RS11000	COG2193	ferroxidase activity
N8I87_RS11010	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
N8I87_RS11020	COG0205	6-phosphofructokinase activity
N8I87_RS11055	COG1940	carbohydrate kinase activity
N8I87_RS11065	COG0003	Pfam Anion-transporting ATPase
N8I87_RS11110	COG1388	LysM domain
N8I87_RS11110	COG0791	NLP P60 protein
N8I87_RS11110	COG3103	Sh3 type 3 domain protein
N8I87_RS11130	COG1960	acyl-CoA dehydrogenase activity
N8I87_RS11140	COG0142	geranyltranstransferase activity
N8I87_RS11150	COG2124	cytochrome p450
N8I87_RS11155	COG2124	cytochrome p450
N8I87_RS11170	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N8I87_RS11180	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
N8I87_RS11185	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
N8I87_RS11190	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
N8I87_RS11195	COG0723	plastoquinol--plastocyanin reductase activity
N8I87_RS11200	COG2010	Cytochrome c
N8I87_RS11205	COG1845	cytochrome c oxidase, subunit III
N8I87_RS11215	COG1376	ErfK ybiS ycfS ynhG family protein
N8I87_RS11225	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
N8I87_RS11230	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
N8I87_RS11240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N8I87_RS11260	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
N8I87_RS11265	COG2197	response regulator
N8I87_RS11290	COG2226	methyltransferase
N8I87_RS11310	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
N8I87_RS11315	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
N8I87_RS11315	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
N8I87_RS11340	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
N8I87_RS11345	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N8I87_RS11350	COG0508	dehydrogenase complex catalyzes the overall conversion of
N8I87_RS11360	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
N8I87_RS11415	COG0321	lipoyl(octanoyl) transferase activity
N8I87_RS11420	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
N8I87_RS11440	COG0174	glutamine synthetase
N8I87_RS11470	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N8I87_RS11485	COG2353	YceI-like domain
N8I87_RS11500	COG0501	Belongs to the peptidase M48B family
N8I87_RS11550	COG0745	RESPONSE REGULATOR receiver
N8I87_RS11565	COG2197	response regulator
N8I87_RS11600	COG1309	transcriptional regulator
N8I87_RS11625	COG0366	Alpha amylase catalytic
N8I87_RS11630	COG3833	ABC-type maltose transport systems, permease component
N8I87_RS11635	COG1175	transmembrane transport
N8I87_RS11645	COG1609	Transcriptional regulator
N8I87_RS11655	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
N8I87_RS11660	COG0174	glutamine synthetase
N8I87_RS11670	COG1959	2 iron, 2 sulfur cluster binding
N8I87_RS11755	COG2814	Major facilitator Superfamily
N8I87_RS11770	COG0477	Major facilitator Superfamily
N8I87_RS11775	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
N8I87_RS11800	COG1994	Peptidase M50
N8I87_RS11840	COG0384	phenazine biosynthesis protein PhzF
N8I87_RS11855	COG2837	iron assimilation
N8I87_RS11860	COG0672	)-iron permease
N8I87_RS11875	COG1309	transcriptional regulator
N8I87_RS11880	COG1834	amidinotransferase
N8I87_RS11890	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
N8I87_RS11895	COG2814	Major facilitator Superfamily
N8I87_RS11905	COG1028	Short-chain dehydrogenase reductase Sdr
N8I87_RS11920	COG1136	(ABC) transporter
N8I87_RS12025	COG3022	response to hydroperoxide
N8I87_RS12030	COG0800	Aldolase
N8I87_RS12045	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
N8I87_RS12060	COG1028	Short-chain dehydrogenase reductase Sdr
N8I87_RS12070	COG2030	dehydratase
N8I87_RS12080	COG4585	Histidine kinase
N8I87_RS12095	COG3415	Transposase
N8I87_RS12095	COG2801	Transposase and inactivated derivatives
N8I87_RS12105	COG2197	response regulator
N8I87_RS12125	COG0183	Belongs to the thiolase family
N8I87_RS12130	COG0477	Major facilitator Superfamily
N8I87_RS12140	COG0860	N-Acetylmuramoyl-L-alanine amidase
N8I87_RS12140	COG2247	cell wall binding repeat
N8I87_RS12150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N8I87_RS12175	COG0438	transferase activity, transferring glycosyl groups
N8I87_RS12180	COG1309	transcriptional regulator
N8I87_RS12200	COG1657	PFAM Prenyltransferase squalene oxidase
N8I87_RS12215	COG3845	ABC transporter
N8I87_RS12230	COG3619	membrane
N8I87_RS12235	COG2124	cytochrome p450
N8I87_RS12240	COG0183	Belongs to the thiolase family
N8I87_RS12290	COG4122	O-methyltransferase activity
N8I87_RS12310	COG2378	regulation of single-species biofilm formation
N8I87_RS12335	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
N8I87_RS12370	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
N8I87_RS12415	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
N8I87_RS12430	COG1358	cellular component organization or biogenesis
N8I87_RS12475	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
N8I87_RS12480	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
N8I87_RS12485	COG0477	Major facilitator Superfamily
N8I87_RS12490	COG1309	transcriptional regulator
N8I87_RS12505	COG0789	Transcriptional regulator
N8I87_RS12515	COG1741	Belongs to the pirin family
N8I87_RS12530	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
N8I87_RS12535	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
N8I87_RS12540	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
N8I87_RS12595	COG2130	NADP-dependent
N8I87_RS12615	COG4948	Mandelate Racemase Muconate Lactonizing
N8I87_RS12640	COG4214	carbohydrate transport
N8I87_RS12690	COG3386	PFAM SMP-30 Gluconolaconase
N8I87_RS12695	COG1414	Transcriptional regulator
N8I87_RS12725	COG4981	capsule polysaccharide biosynthetic process
N8I87_RS12775	COG0318	PFAM AMP-dependent synthetase and ligase
N8I87_RS12780	COG0825	malonyl-CoA metabolic process
N8I87_RS12780	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
N8I87_RS12790	COG1077	Cell shape determining protein MreB Mrl
N8I87_RS12845	COG0583	DNA-binding transcription factor activity
N8I87_RS12895	COG2161	toxin-antitoxin pair type II binding
N8I87_RS12900	COG4115	mRNA cleavage
N8I87_RS12925	COG1070	Carbohydrate kinase
N8I87_RS12940	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
N8I87_RS12945	COG0358	DNA primase activity
N8I87_RS12955	COG0232	Belongs to the dGTPase family. Type 2 subfamily
N8I87_RS12965	COG2949	membrane
N8I87_RS12975	COG0243	molybdopterin cofactor binding
N8I87_RS12990	COG0515	serine threonine protein kinase
N8I87_RS13010	COG0477	Major facilitator Superfamily
N8I87_RS13030	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
N8I87_RS13035	COG2146	nitrite reductase [NAD(P)H] activity
N8I87_RS13035	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
N8I87_RS13045	COG1028	Short-chain dehydrogenase reductase Sdr
N8I87_RS13060	COG0642	Histidine kinase
N8I87_RS13080	COG0574	Belongs to the PEP-utilizing enzyme family
N8I87_RS13080	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
N8I87_RS13085	COG1940	carbohydrate kinase activity
N8I87_RS13085	COG1846	Transcriptional regulator
N8I87_RS13090	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
N8I87_RS13120	COG0477	Major facilitator Superfamily
N8I87_RS13140	COG0667	Aldo Keto reductase
N8I87_RS13150	COG1280	lysine exporter protein (LysE YggA)
N8I87_RS13155	COG0423	glycine-tRNA ligase activity
N8I87_RS13160	COG3443	Belongs to the bacterial solute-binding protein 9 family
N8I87_RS13160	COG0803	Belongs to the bacterial solute-binding protein 9 family
N8I87_RS13165	COG1121	(ABC) transporter
N8I87_RS13170	COG1108	ABC-type Mn2 Zn2 transport systems permease components
N8I87_RS13190	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
N8I87_RS13195	COG1381	Involved in DNA repair and RecF pathway recombination
N8I87_RS13210	COG2186	Transcriptional regulator
N8I87_RS13215	COG0747	negative chemotaxis
N8I87_RS13225	COG0444	Belongs to the ABC transporter superfamily
N8I87_RS13230	COG4608	Belongs to the ABC transporter superfamily
N8I87_RS13235	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N8I87_RS13245	COG2197	response regulator
N8I87_RS13250	COG4585	Histidine kinase
N8I87_RS13255	COG2409	Drug exporters of the RND superfamily
N8I87_RS13265	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
N8I87_RS13280	COG2723	6-phospho-beta-galactosidase activity
N8I87_RS13295	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
N8I87_RS13330	COG2315	Protein conserved in bacteria
N8I87_RS13340	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
N8I87_RS13355	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N8I87_RS13360	COG4948	Mandelate Racemase Muconate Lactonizing
N8I87_RS13370	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
N8I87_RS13375	COG1234	tRNA 3'-trailer cleavage
N8I87_RS13380	COG0537	adenosine 5'-monophosphoramidase activity
N8I87_RS13385	COG0793	Belongs to the peptidase S41A family
N8I87_RS13385	COG4946	Tricorn protease homolog
N8I87_RS13410	COG0484	heat shock protein binding
N8I87_RS13415	COG1420	regulation of RNA biosynthetic process
N8I87_RS13460	COG0481	GTPase activity
N8I87_RS13465	COG0268	Binds directly to 16S ribosomal RNA
N8I87_RS13535	COG1555	photosystem II stabilization
N8I87_RS13540	COG1307	EDD domain protein, DegV family
N8I87_RS13550	COG0495	leucyl-tRNA aminoacylation
N8I87_RS13560	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
N8I87_RS13585	COG0477	Major facilitator Superfamily
N8I87_RS13600	COG0588	phosphoglycerate mutase activity
N8I87_RS13605	COG0799	negative regulation of ribosome biogenesis
N8I87_RS13615	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
N8I87_RS13630	COG0501	Belongs to the peptidase M48B family
N8I87_RS13645	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
N8I87_RS13655	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
N8I87_RS13670	COG1215	transferase activity, transferring glycosyl groups
N8I87_RS13690	COG3540	Alkaline phosphatase
N8I87_RS13700	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
N8I87_RS13705	COG0211	Belongs to the bacterial ribosomal protein bL27 family
N8I87_RS13710	COG0261	This protein binds to 23S rRNA in the presence of protein L20
N8I87_RS13790	COG0277	FAD linked oxidase domain protein
N8I87_RS13850	COG2186	Transcriptional regulator
N8I87_RS13885	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
N8I87_RS13915	COG0772	Belongs to the SEDS family
N8I87_RS13920	COG0768	penicillin binding
N8I87_RS13935	COG1077	Cell shape determining protein MreB Mrl
N8I87_RS13940	COG0105	UTP biosynthetic process
N8I87_RS13950	COG0285	dihydrofolate synthase activity
N8I87_RS13955	COG0525	valine-tRNA ligase activity
N8I87_RS13965	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
N8I87_RS13970	COG0740	serine-type endopeptidase activity
N8I87_RS13975	COG0740	serine-type endopeptidase activity
N8I87_RS13980	COG0544	peptidyl-prolyl cis-trans isomerase activity
N8I87_RS14000	COG3594	Acyltransferase
N8I87_RS14005	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
N8I87_RS14015	COG4552	Acetyltransferase involved in intracellular survival and related
N8I87_RS14025	COG0698	ribose 5-phosphate isomerase
N8I87_RS14030	COG1113	amino acid transport
N8I87_RS14035	COG0515	serine threonine protein kinase
N8I87_RS14055	COG0588	phosphoglycerate mutase activity
N8I87_RS14065	COG1653	transport
N8I87_RS14070	COG1175	transmembrane transport
N8I87_RS14075	COG0395	ABC-type sugar transport system, permease component
N8I87_RS14080	COG3842	ATPase activity
N8I87_RS14085	COG1349	DNA-binding transcription factor activity
N8I87_RS14110	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
N8I87_RS14180	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N8I87_RS14210	COG1136	(ABC) transporter
N8I87_RS14225	COG0668	transmembrane transport
N8I87_RS14240	COG1653	transport
N8I87_RS14245	COG1175	transmembrane transport
N8I87_RS14250	COG0395	ABC-type sugar transport system, permease component
N8I87_RS14255	COG1486	melibiose metabolic process
N8I87_RS14270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N8I87_RS14300	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
N8I87_RS14330	COG0629	single-stranded DNA binding
N8I87_RS14360	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
N8I87_RS14460	COG3962	Belongs to the TPP enzyme family
N8I87_RS14465	COG3718	enzyme involved in inositol metabolism
N8I87_RS14475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N8I87_RS14485	COG1063	alcohol dehydrogenase
N8I87_RS14490	COG2409	Drug exporters of the RND superfamily
N8I87_RS14520	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
N8I87_RS14590	COG1674	ftsk spoiiie
N8I87_RS14615	COG0673	inositol 2-dehydrogenase activity
N8I87_RS14625	COG1846	Transcriptional regulator
N8I87_RS14625	COG0456	acetyltransferase
N8I87_RS14645	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
N8I87_RS14650	COG1472	Belongs to the glycosyl hydrolase 3 family
N8I87_RS14700	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
N8I87_RS14730	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
N8I87_RS14745	COG0028	Belongs to the TPP enzyme family
N8I87_RS14770	COG1946	Acyl-CoA thioesterase
N8I87_RS14785	COG1309	transcriptional regulator
N8I87_RS14790	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
N8I87_RS14805	COG1960	acyl-CoA dehydrogenase activity
N8I87_RS14830	COG3486	L-lysine 6-monooxygenase (NADPH) activity
N8I87_RS14865	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
N8I87_RS14875	COG0589	response to stress
N8I87_RS14885	COG4977	sequence-specific DNA binding
N8I87_RS14890	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
N8I87_RS14950	COG0395	ABC-type sugar transport system, permease component
N8I87_RS14965	COG3979	chitinase
N8I87_RS14975	COG0745	RESPONSE REGULATOR receiver
N8I87_RS14985	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
N8I87_RS15000	COG0406	alpha-ribazole phosphatase activity
N8I87_RS15050	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N8I87_RS15060	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
N8I87_RS15065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N8I87_RS15070	COG0765	amino acid transport
N8I87_RS15075	COG0765	amino acid transport
N8I87_RS15080	COG1126	abc transporter atp-binding protein
N8I87_RS15095	COG0318	PFAM AMP-dependent synthetase and ligase
N8I87_RS15105	COG3397	chitin binding
N8I87_RS15125	COG2186	Transcriptional regulator
N8I87_RS15170	COG1940	carbohydrate kinase activity
N8I87_RS15175	COG0673	inositol 2-dehydrogenase activity
N8I87_RS15180	COG4702	Belongs to the UPF0303 family
N8I87_RS15195	COG0706	membrane insertase activity
N8I87_RS15215	COG3764	Sortase (surface protein transpeptidase)
N8I87_RS15370	COG2733	membrane
N8I87_RS15385	COG4555	ABC transporter
N8I87_RS15400	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
N8I87_RS15430	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
N8I87_RS15440	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
N8I87_RS15445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N8I87_RS15450	COG1263	PTS System
N8I87_RS15455	COG1263	PTS System
N8I87_RS15500	COG1335	isochorismatase
N8I87_RS15510	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
N8I87_RS15520	COG1113	amino acid transport
N8I87_RS15580	COG0277	FAD linked oxidase domain protein
N8I87_RS15590	COG3185	4-Hydroxyphenylpyruvate dioxygenase
N8I87_RS15600	COG1174	glycine betaine transport
N8I87_RS15605	COG1125	glycine betaine transport
N8I87_RS15605	COG0517	IMP dehydrogenase activity
N8I87_RS15610	COG1174	glycine betaine transport
N8I87_RS15625	COG4948	Mandelate Racemase Muconate Lactonizing
N8I87_RS15640	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N8I87_RS15650	COG0531	amino acid
N8I87_RS15665	COG3654	unkown
N8I87_RS15710	COG1529	Aldehyde oxidase and xanthine dehydrogenase
N8I87_RS15725	COG3525	Glycosyl hydrolase, family 20, catalytic domain
N8I87_RS15735	COG1678	Uncharacterized ACR, COG1678
N8I87_RS15740	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
N8I87_RS15745	COG0776	regulation of translation
N8I87_RS15755	COG3973	AAA domain
N8I87_RS15785	COG2223	nitrite transmembrane transporter activity
N8I87_RS15830	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
N8I87_RS15835	COG0793	Belongs to the peptidase S41A family
N8I87_RS15840	COG2177	Part of the ABC transporter FtsEX involved in
N8I87_RS15845	COG2884	Cell division ATP-binding protein ftsE
N8I87_RS15860	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
N8I87_RS15865	COG0515	serine threonine protein kinase
N8I87_RS15885	COG1175	transmembrane transport
N8I87_RS15890	COG0395	ABC-type sugar transport system, permease component
N8I87_RS15895	COG0463	Glycosyl transferase, family 2
N8I87_RS15895	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
N8I87_RS15900	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
N8I87_RS15905	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
N8I87_RS15915	COG1764	response to oxidative stress
N8I87_RS15920	COG1846	Transcriptional regulator
N8I87_RS15935	COG1215	transferase activity, transferring glycosyl groups
N8I87_RS15960	COG1134	teichoic acid transport
N8I87_RS15965	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
N8I87_RS15970	COG1215	transferase activity, transferring glycosyl groups
N8I87_RS15985	COG2902	Dehydrogenase
N8I87_RS16005	COG0653	protein targeting
N8I87_RS16015	COG3214	Protein conserved in bacteria
N8I87_RS16020	COG2197	response regulator
N8I87_RS16025	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
N8I87_RS16035	COG0823	Involved in the tonB-independent uptake of proteins
N8I87_RS16040	COG5002	protein histidine kinase activity
N8I87_RS16040	COG5000	phosphorelay sensor kinase activity
N8I87_RS16045	COG0745	RESPONSE REGULATOR receiver
N8I87_RS16050	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
N8I87_RS16070	COG0714	Associated with various cellular activities
N8I87_RS16110	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
N8I87_RS16115	COG0681	Belongs to the peptidase S26 family
N8I87_RS16125	COG1482	cell wall glycoprotein biosynthetic process
N8I87_RS16135	COG2835	tetraacyldisaccharide 4'-kinase activity
N8I87_RS16140	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
N8I87_RS16175	COG0391	Required for morphogenesis under gluconeogenic growth conditions
N8I87_RS16180	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
N8I87_RS16180	COG0778	Nitroreductase
N8I87_RS16205	COG1316	TRANSCRIPTIONal
N8I87_RS16210	COG1316	TRANSCRIPTIONal
N8I87_RS16215	COG1316	TRANSCRIPTIONal
N8I87_RS16230	COG1316	TRANSCRIPTIONal
N8I87_RS16240	COG1316	TRANSCRIPTIONal
N8I87_RS16280	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
N8I87_RS16295	COG2205	protein histidine kinase activity
N8I87_RS16300	COG0745	RESPONSE REGULATOR receiver
N8I87_RS16305	COG3104	oligopeptide transport
N8I87_RS16335	COG1366	Belongs to the anti-sigma-factor antagonist family
N8I87_RS16340	COG1191	sigma factor activity
N8I87_RS16350	COG1228	amidohydrolase
N8I87_RS16360	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N8I87_RS16365	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
N8I87_RS16405	COG2986	histidine ammonia-lyase
N8I87_RS16425	COG2755	lipolytic protein G-D-S-L family
N8I87_RS16430	COG0183	Belongs to the thiolase family
N8I87_RS16460	COG1136	(ABC) transporter
N8I87_RS16460	COG0577	efflux transmembrane transporter activity
N8I87_RS16465	COG0577	efflux transmembrane transporter activity
N8I87_RS16470	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
N8I87_RS16475	COG1252	NADH dehydrogenase
N8I87_RS16495	COG0148	phosphopyruvate hydratase activity
N8I87_RS16505	COG1652	LysM domain
N8I87_RS16585	COG0577	efflux transmembrane transporter activity
N8I87_RS16585	COG1136	(ABC) transporter
N8I87_RS16590	COG1136	(ABC) transporter
N8I87_RS16595	COG0477	Major facilitator Superfamily
N8I87_RS16605	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N8I87_RS16635	COG4585	Histidine kinase
N8I87_RS16650	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
N8I87_RS16655	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
N8I87_RS16660	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
N8I87_RS16665	COG0193	aminoacyl-tRNA hydrolase activity
N8I87_RS16680	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
N8I87_RS16690	COG1309	transcriptional regulator
N8I87_RS16705	COG4106	trans-aconitate 2-methyltransferase activity
N8I87_RS16710	COG1846	Transcriptional regulator
N8I87_RS16715	COG2197	response regulator
N8I87_RS16725	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
N8I87_RS16765	COG0488	(ABC) transporter
N8I87_RS16775	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
N8I87_RS16780	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
N8I87_RS16790	COG0084	hydrolase, TatD family'
N8I87_RS16825	COG0310	cobalt ion transport
N8I87_RS16835	COG1122	ATPase activity
N8I87_RS16840	COG1846	Transcriptional regulator
N8I87_RS16845	COG1764	response to oxidative stress
N8I87_RS16850	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
N8I87_RS16860	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
N8I87_RS16885	COG2409	Drug exporters of the RND superfamily
N8I87_RS16895	COG0793	Belongs to the peptidase S41A family
N8I87_RS16895	COG4946	Tricorn protease homolog
N8I87_RS16905	COG1028	Short-chain dehydrogenase reductase Sdr
N8I87_RS16910	COG2267	carboxylic ester hydrolase activity
N8I87_RS16915	COG2072	flavoprotein involved in K transport
N8I87_RS16930	COG0708	Exodeoxyribonuclease III
N8I87_RS16950	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N8I87_RS16955	COG0521	Mo-molybdopterin cofactor biosynthetic process
N8I87_RS16955	COG0315	cyclic pyranopterin monophosphate synthase activity
N8I87_RS16960	COG0315	cyclic pyranopterin monophosphate synthase activity
N8I87_RS16970	COG1210	Utp--glucose-1-phosphate uridylyltransferase
N8I87_RS16975	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
N8I87_RS17000	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
N8I87_RS17010	COG1970	mechanosensitive ion channel activity
N8I87_RS17025	COG3191	aminopeptidase activity
N8I87_RS17030	COG1376	ErfK ybiS ycfS ynhG family protein
N8I87_RS17045	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N8I87_RS17045	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N8I87_RS17045	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N8I87_RS17055	COG1349	DNA-binding transcription factor activity
N8I87_RS17060	COG0477	Major facilitator Superfamily
N8I87_RS17080	COG1247	-acetyltransferase
N8I87_RS17085	COG3384	dioxygenase
N8I87_RS17090	COG1846	Transcriptional regulator
N8I87_RS17115	COG0582	viral genome integration into host DNA
N8I87_RS17255	COG0604	alcohol dehydrogenase
N8I87_RS17275	COG1278	Cold shock
N8I87_RS17325	COG2268	Band 7 protein
N8I87_RS17335	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
N8I87_RS17360	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
N8I87_RS17385	COG0330	HflC and HflK could
N8I87_RS17400	COG0386	Belongs to the glutathione peroxidase family
N8I87_RS17505	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
N8I87_RS17535	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
N8I87_RS17545	COG1028	Short-chain dehydrogenase reductase Sdr
N8I87_RS17560	COG3903	Transcriptional regulator
N8I87_RS17560	COG3629	intracellular signal transduction
N8I87_RS17615	COG1024	Enoyl-CoA hydratase
N8I87_RS17635	COG1309	transcriptional regulator
N8I87_RS17645	COG1280	lysine exporter protein (LysE YggA)
N8I87_RS17655	COG1960	acyl-CoA dehydrogenase activity
N8I87_RS17705	COG2072	flavoprotein involved in K transport
N8I87_RS17710	COG1231	oxidoreductase activity
N8I87_RS17735	COG2814	Major facilitator Superfamily
N8I87_RS17740	COG0019	diaminopimelate decarboxylase activity
N8I87_RS17760	COG5000	phosphorelay sensor kinase activity
N8I87_RS17760	COG5002	protein histidine kinase activity
N8I87_RS17765	COG0745	RESPONSE REGULATOR receiver
N8I87_RS17775	COG1024	Enoyl-CoA hydratase
N8I87_RS17790	COG2271	Major facilitator Superfamily
N8I87_RS17795	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
N8I87_RS17800	COG1960	acyl-CoA dehydrogenase activity
N8I87_RS17805	COG1028	Short-chain dehydrogenase reductase Sdr
N8I87_RS17825	COG1960	acyl-CoA dehydrogenase activity
N8I87_RS17830	COG1960	acyl-CoA dehydrogenase activity
N8I87_RS17835	COG0318	PFAM AMP-dependent synthetase and ligase
N8I87_RS17890	COG1131	(ABC) transporter
N8I87_RS17900	COG2945	thiolester hydrolase activity
N8I87_RS17900	COG0596	Alpha beta hydrolase
N8I87_RS17910	COG4821	SIS domain
N8I87_RS17930	COG0259	pyridoxamine-phosphate oxidase activity
N8I87_RS17950	COG1024	Enoyl-CoA hydratase
N8I87_RS17955	COG0318	PFAM AMP-dependent synthetase and ligase
N8I87_RS17970	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
N8I87_RS18015	COG1132	(ABC) transporter
N8I87_RS18035	COG0277	FAD linked oxidase domain protein
N8I87_RS18035	COG0247	lactate metabolic process
N8I87_RS18040	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
N8I87_RS18070	COG0667	Aldo Keto reductase
N8I87_RS18100	COG2252	PERMEase
N8I87_RS18110	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
N8I87_RS18140	COG2814	Major facilitator Superfamily
N8I87_RS18150	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
N8I87_RS18155	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
N8I87_RS18185	COG1061	Type III restriction enzyme res subunit
N8I87_RS18200	COG3973	AAA domain
N8I87_RS18205	COG3415	Transposase
N8I87_RS18205	COG2801	Transposase and inactivated derivatives
N8I87_RS18240	COG1737	Transcriptional regulator
N8I87_RS18245	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
N8I87_RS18250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N8I87_RS18250	COG1263	PTS System
N8I87_RS18280	COG0459	protein refolding
N8I87_RS18300	COG0463	Glycosyl transferase, family 2
N8I87_RS18345	COG3300	MHYT domain
N8I87_RS18345	COG5001	Diguanylate cyclase
N8I87_RS18365	COG0494	nUDIX hydrolase
N8I87_RS18440	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
N8I87_RS18455	COG0662	Cupin 2, conserved barrel domain protein
N8I87_RS18465	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N8I87_RS18475	COG3842	ATPase activity
N8I87_RS18500	COG0215	cysteine-tRNA ligase activity
N8I87_RS18505	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
N8I87_RS18510	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
N8I87_RS18515	COG1329	Transcriptional regulator
N8I87_RS18530	COG5002	protein histidine kinase activity
N8I87_RS18565	COG0588	phosphoglycerate mutase activity
N8I87_RS18590	COG0438	transferase activity, transferring glycosyl groups
N8I87_RS18645	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
N8I87_RS18660	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
N8I87_RS18675	COG1309	transcriptional regulator
N8I87_RS18690	COG2186	Transcriptional regulator
N8I87_RS18705	COG4552	Acetyltransferase involved in intracellular survival and related
N8I87_RS18715	COG1490	D-aminoacyl-tRNA deacylase activity
N8I87_RS18720	COG0354	folic acid binding
N8I87_RS18730	COG3485	protocatechuate 3,4-dioxygenase
N8I87_RS18780	COG2897	thiosulfate sulfurtransferase activity
N8I87_RS18805	COG0745	RESPONSE REGULATOR receiver
N8I87_RS18810	COG1609	Transcriptional regulator
N8I87_RS18815	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N8I87_RS18825	COG0745	RESPONSE REGULATOR receiver
N8I87_RS18845	COG3866	Pectate lyase
N8I87_RS18850	COG0737	Belongs to the 5'-nucleotidase family
N8I87_RS18855	COG0456	acetyltransferase
N8I87_RS18870	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
N8I87_RS18880	COG0494	nUDIX hydrolase
N8I87_RS18880	COG0406	alpha-ribazole phosphatase activity
N8I87_RS18895	COG1937	Protein conserved in bacteria
N8I87_RS18905	COG0306	phosphate transporter
N8I87_RS18910	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
N8I87_RS18915	COG0581	inorganic phosphate transmembrane transporter activity
N8I87_RS18930	COG0277	FAD linked oxidase domain protein
N8I87_RS18940	COG0671	phosphoesterase, PA-phosphatase related
N8I87_RS18945	COG0741	lytic transglycosylase activity
N8I87_RS18945	COG1196	nuclear chromosome segregation
N8I87_RS18945	COG0739	heme binding
N8I87_RS19010	COG0675	Transposase, IS605 OrfB family
N8I87_RS19045	COG2226	methyltransferase
N8I87_RS19085	COG0579	oxidoreductase
N8I87_RS19090	COG0220	tRNA (guanine-N7-)-methyltransferase activity
N8I87_RS19110	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
N8I87_RS19110	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
N8I87_RS19120	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
N8I87_RS19125	COG1605	Chorismate mutase
N8I87_RS19155	COG0174	glutamine synthetase
N8I87_RS19160	COG0512	Glutamine amidotransferase of anthranilate synthase
N8I87_RS19160	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
N8I87_RS19190	COG0513	Belongs to the DEAD box helicase family
N8I87_RS19230	COG1643	Atp-dependent helicase
N8I87_RS19265	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
N8I87_RS19290	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
N8I87_RS19295	COG0047	phosphoribosylformylglycinamidine synthase activity
N8I87_RS19300	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
N8I87_RS19335	COG2197	response regulator
N8I87_RS19345	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
N8I87_RS19360	COG0151	Belongs to the GarS family
N8I87_RS19435	COG0823	Involved in the tonB-independent uptake of proteins
N8I87_RS19515	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
N8I87_RS19550	COG1191	sigma factor activity
N8I87_RS19555	COG1191	sigma factor activity
N8I87_RS19575	COG0477	Major facilitator Superfamily
N8I87_RS19580	COG2353	YceI-like domain
N8I87_RS19585	COG3467	pyridoxamine 5'-phosphate
N8I87_RS19595	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
N8I87_RS19605	COG2205	protein histidine kinase activity
N8I87_RS19610	COG0745	RESPONSE REGULATOR receiver
N8I87_RS19625	COG0675	Transposase, IS605 OrfB family
N8I87_RS19820	COG0318	PFAM AMP-dependent synthetase and ligase
N8I87_RS19825	COG1595	DNA-templated transcription, initiation
N8I87_RS19850	COG1960	acyl-CoA dehydrogenase activity
N8I87_RS19890	COG1051	belongs to the nudix hydrolase family
N8I87_RS19915	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N8I87_RS19930	COG0653	protein targeting
N8I87_RS19950	COG0006	proline dipeptidase activity
N8I87_RS19995	COG1999	signal sequence binding
N8I87_RS20010	COG2837	iron assimilation
N8I87_RS20020	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
N8I87_RS20025	COG0561	phosphatase activity
N8I87_RS20075	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
N8I87_RS20090	COG0561	phosphatase activity
N8I87_RS20095	COG4988	ABC transporter
N8I87_RS20100	COG1294	oxidase, subunit
N8I87_RS20105	COG1271	oxidase subunit
N8I87_RS20110	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
N8I87_RS20115	COG1609	Transcriptional regulator
N8I87_RS20120	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
N8I87_RS20130	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
N8I87_RS20155	COG0662	Cupin 2, conserved barrel domain protein
N8I87_RS20160	COG1950	PFAM Membrane protein of
N8I87_RS20165	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
N8I87_RS20170	COG0626	cystathionine gamma-synthase activity
N8I87_RS20195	COG2814	Major facilitator Superfamily
N8I87_RS20205	COG0456	acetyltransferase
N8I87_RS20215	COG0305	Participates in initiation and elongation during chromosome replication
N8I87_RS20225	COG0359	binds to the 23S rRNA
N8I87_RS20230	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
N8I87_RS20235	COG0629	single-stranded DNA binding
N8I87_RS20240	COG0360	Binds together with S18 to 16S ribosomal RNA
N8I87_RS20265	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
N8I87_RS20290	COG0617	tRNA 3'-terminal CCA addition
N8I87_RS20305	COG2815	serine threonine protein kinase
N8I87_RS20305	COG0515	serine threonine protein kinase
N8I87_RS20310	COG1595	DNA-templated transcription, initiation
N8I87_RS20320	COG0492	ferredoxin-NADP+ reductase activity
N8I87_RS20325	COG3118	belongs to the thioredoxin family
N8I87_RS20340	COG1192	Involved in chromosome partitioning
N8I87_RS20345	COG0357	Ribosomal RNA small subunit methyltransferase G
N8I87_RS20355	COG0706	membrane insertase activity
N8I87_RS20360	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
N8I87_RS20365	COG0594	ribonuclease P activity
N8I87_RS20370	COG0230	Belongs to the bacterial ribosomal protein bL34 family
N8I87_RS20375	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
N8I87_RS20385	COG0592	DNA-directed DNA polymerase activity
N8I87_RS20390	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
N8I87_RS20395	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
N8I87_RS20400	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
N8I87_RS20405	COG0187	DNA topoisomerase II activity
N8I87_RS20410	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
N8I87_RS20425	COG4249	Peptidase C14 caspase catalytic subunit p20
N8I87_RS20425	COG2319	Wd-40 repeat
N8I87_RS20445	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
N8I87_RS20475	COG0515	serine threonine protein kinase
N8I87_RS20490	COG0137	argininosuccinate synthase activity
N8I87_RS20495	COG0137	argininosuccinate synthase activity
N8I87_RS20530	COG1012	belongs to the aldehyde dehydrogenase family
N8I87_RS20545	COG4585	Histidine kinase
N8I87_RS20550	COG2197	response regulator
N8I87_RS20565	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
N8I87_RS20580	COG0535	radical SAM domain protein
N8I87_RS20610	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
N8I87_RS20615	COG0563	adenylate kinase activity
N8I87_RS20620	COG0248	Ppx GppA phosphatase
N8I87_RS20635	COG0705	Rhomboid family
N8I87_RS20650	COG3764	Sortase (surface protein transpeptidase)
N8I87_RS20665	COG3764	Sortase (surface protein transpeptidase)
N8I87_RS20670	COG3764	Sortase (surface protein transpeptidase)
N8I87_RS20675	COG0515	serine threonine protein kinase
N8I87_RS20680	COG0768	penicillin binding
N8I87_RS20695	COG1716	ATPase activity
N8I87_RS20700	COG1716	ATPase activity
N8I87_RS20720	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
N8I87_RS20730	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
N8I87_RS20735	COG2151	metal-sulfur cluster biosynthetic enzyme
N8I87_RS20740	COG3396	Phenylacetate-CoA oxygenase
N8I87_RS20745	COG3460	Phenylacetate-CoA oxygenase
N8I87_RS20750	COG3396	Phenylacetate-CoA oxygenase
N8I87_RS20775	COG1250	3-hydroxyacyl-CoA dehydrogenase
N8I87_RS20780	COG1309	transcriptional regulator
N8I87_RS20785	COG1522	sequence-specific DNA binding
N8I87_RS20805	COG0746	molybdenum cofactor guanylyltransferase activity
N8I87_RS20830	COG1028	Short-chain dehydrogenase reductase Sdr
N8I87_RS20830	COG0604	alcohol dehydrogenase
N8I87_RS20830	COG3321	synthase
N8I87_RS20845	COG0515	serine threonine protein kinase
N8I87_RS20850	COG0515	serine threonine protein kinase
N8I87_RS20865	COG0022	dehydrogenase e1 component
N8I87_RS20870	COG0508	dehydrogenase complex catalyzes the overall conversion of
N8I87_RS20885	COG2814	Major facilitator Superfamily
N8I87_RS20905	COG3290	protein histidine kinase activity
N8I87_RS20930	COG1362	aminopeptidase activity
N8I87_RS20935	COG1960	acyl-CoA dehydrogenase activity
N8I87_RS20950	COG1741	Belongs to the pirin family
N8I87_RS20965	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
N8I87_RS20995	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N8I87_RS21060	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
N8I87_RS21065	COG1957	nucleoside hydrolase
N8I87_RS21100	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
N8I87_RS21105	COG2326	polyphosphate kinase activity
N8I87_RS21120	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
N8I87_RS21135	COG3284	Transcriptional regulator
N8I87_RS21145	COG3387	PFAM Glycoside hydrolase 15-related
N8I87_RS21150	COG0477	Major facilitator Superfamily
N8I87_RS21180	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
N8I87_RS21185	COG1595	DNA-templated transcription, initiation
N8I87_RS21190	COG1252	NADH dehydrogenase
N8I87_RS21255	COG0702	epimerase
N8I87_RS21295	COG0717	Belongs to the dCTP deaminase family
N8I87_RS21315	COG2801	Transposase and inactivated derivatives
N8I87_RS21440	COG2181	nitrate reductase activity
N8I87_RS21440	COG0247	lactate metabolic process
N8I87_RS21445	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
N8I87_RS21450	COG0443	Heat shock 70 kDa protein
N8I87_RS21455	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
N8I87_RS21460	COG0484	heat shock protein binding
N8I87_RS21465	COG0789	Transcriptional regulator
N8I87_RS21470	COG4213	ABC transporter substrate-binding protein
N8I87_RS21495	COG0542	response to heat
N8I87_RS21520	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N8I87_RS21540	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
N8I87_RS21555	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
N8I87_RS21560	COG0191	fructose-bisphosphate aldolase activity
N8I87_RS21565	COG0477	Major facilitator Superfamily
N8I87_RS21580	COG3844	kynureninase activity
N8I87_RS21600	COG4585	Histidine kinase
N8I87_RS21605	COG2197	response regulator
N8I87_RS21610	COG4585	Histidine kinase
N8I87_RS21615	COG2197	response regulator
N8I87_RS21625	COG3559	Exporter of polyketide antibiotics
N8I87_RS21630	COG1131	(ABC) transporter
N8I87_RS21645	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
N8I87_RS21650	COG0737	Belongs to the 5'-nucleotidase family
N8I87_RS21665	COG0463	Glycosyl transferase, family 2
N8I87_RS21670	COG1802	Transcriptional regulator
N8I87_RS21690	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
N8I87_RS21695	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
N8I87_RS21715	COG1595	DNA-templated transcription, initiation
N8I87_RS21745	COG0701	Predicted permease
N8I87_RS21755	COG1280	lysine exporter protein (LysE YggA)
N8I87_RS21800	COG1408	metallophosphoesterase
N8I87_RS21820	COG0003	Pfam Anion-transporting ATPase
N8I87_RS21845	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N8I87_RS21880	COG2267	carboxylic ester hydrolase activity
N8I87_RS21895	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
N8I87_RS21960	COG1111	helicase
N8I87_RS21960	COG1205	dead DEAH box helicase
N8I87_RS21965	COG1366	Belongs to the anti-sigma-factor antagonist family
N8I87_RS21970	COG2172	sigma factor antagonist activity
N8I87_RS21975	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
N8I87_RS21995	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
N8I87_RS21995	COG1754	DNA topoisomerase type I activity
N8I87_RS22000	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
N8I87_RS22010	COG0596	Alpha beta hydrolase
N8I87_RS22030	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
N8I87_RS22085	COG2197	response regulator
N8I87_RS22095	COG3655	Transcriptional regulator
N8I87_RS22110	COG1231	oxidoreductase activity
N8I87_RS22130	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
N8I87_RS22130	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
N8I87_RS22140	COG0640	Transcriptional regulator
N8I87_RS22195	COG1012	belongs to the aldehyde dehydrogenase family
N8I87_RS22205	COG2318	DinB family
N8I87_RS22230	COG0076	glutamate decarboxylase activity
N8I87_RS22240	COG0789	Transcriptional regulator
N8I87_RS22250	COG0393	Putative heavy-metal-binding
N8I87_RS22265	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
N8I87_RS22270	COG2027	D-alanyl-D-alanine carboxypeptidase
N8I87_RS22280	COG0037	tRNA processing
N8I87_RS22295	COG0302	gtp cyclohydrolase
N8I87_RS22310	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
N8I87_RS22325	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
N8I87_RS22325	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
N8I87_RS22350	COG0649	NAD binding
N8I87_RS22365	COG2197	response regulator
N8I87_RS22370	COG1660	Displays ATPase and GTPase activities
N8I87_RS22390	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
N8I87_RS22395	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
N8I87_RS22405	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
N8I87_RS22425	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
N8I87_RS22465	COG0477	Major facilitator Superfamily
N8I87_RS22475	COG0346	lactoylglutathione lyase activity
N8I87_RS22480	COG2205	protein histidine kinase activity
N8I87_RS22485	COG0745	RESPONSE REGULATOR receiver
N8I87_RS22495	COG1595	DNA-templated transcription, initiation
N8I87_RS22510	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
N8I87_RS22530	COG0248	Ppx GppA phosphatase
N8I87_RS22535	COG1082	Xylose isomerase domain protein TIM barrel
N8I87_RS22540	COG1309	transcriptional regulator
N8I87_RS22545	COG0129	dihydroxy-acid dehydratase activity
N8I87_RS22550	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
N8I87_RS22550	COG0515	serine threonine protein kinase
N8I87_RS22555	COG4991	sh3 domain protein
N8I87_RS22575	COG0659	secondary active sulfate transmembrane transporter activity
N8I87_RS22580	COG1129	ABC transporter
N8I87_RS22580	COG0842	Transport permease protein
N8I87_RS22590	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
N8I87_RS22595	COG1335	isochorismatase
N8I87_RS22605	COG0180	Tryptophanyl-tRNA synthetase
N8I87_RS22625	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
N8I87_RS22635	COG0738	Major facilitator superfamily
N8I87_RS22640	COG0123	including yeast histone deacetylase and acetoin utilization protein
N8I87_RS22690	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
N8I87_RS22695	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
N8I87_RS22700	COG0181	hydroxymethylbilane synthase activity
N8I87_RS22705	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
N8I87_RS22705	COG1648	precorrin-2 dehydrogenase activity
N8I87_RS22710	COG0590	tRNA wobble adenosine to inosine editing
N8I87_RS22715	COG3224	Antibiotic biosynthesis monooxygenase
N8I87_RS22725	COG0113	porphobilinogen synthase activity
N8I87_RS22740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N8I87_RS22770	COG0018	arginyl-trna synthetase
N8I87_RS22775	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
N8I87_RS22795	COG1690	Belongs to the RtcB family
N8I87_RS22815	COG1742	UPF0060 membrane protein
N8I87_RS22825	COG1846	Transcriptional regulator
N8I87_RS22835	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N8I87_RS22850	COG2205	protein histidine kinase activity
N8I87_RS22860	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
N8I87_RS22860	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
N8I87_RS22880	COG1113	amino acid transport
N8I87_RS22895	COG2815	serine threonine protein kinase
N8I87_RS22895	COG0515	serine threonine protein kinase
N8I87_RS22910	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
N8I87_RS22915	COG0406	alpha-ribazole phosphatase activity
N8I87_RS22930	COG0785	Cytochrome C biogenesis protein
N8I87_RS22935	COG1333	cytochrome c biogenesis protein
N8I87_RS22940	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
N8I87_RS22985	COG0697	spore germination
N8I87_RS22990	COG0583	DNA-binding transcription factor activity
N8I87_RS23000	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
N8I87_RS23010	COG0163	prenyltransferase activity
N8I87_RS23020	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
N8I87_RS23025	COG1573	uracil-dna glycosylase
N8I87_RS23040	COG1309	transcriptional regulator
N8I87_RS23075	COG2124	cytochrome p450
N8I87_RS23090	COG1053	succinate dehydrogenase
N8I87_RS23095	COG4106	trans-aconitate 2-methyltransferase activity
N8I87_RS23110	COG1396	sequence-specific DNA binding
N8I87_RS23115	COG1278	Cold shock
N8I87_RS23120	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
N8I87_RS23205	COG1674	ftsk spoiiie
N8I87_RS23260	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
N8I87_RS23325	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
N8I87_RS23335	COG2226	methyltransferase
N8I87_RS23365	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
N8I87_RS23370	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
N8I87_RS23375	COG0649	NAD binding
N8I87_RS23385	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
N8I87_RS23390	COG1034	ATP synthesis coupled electron transport
N8I87_RS23395	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
N8I87_RS23400	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
N8I87_RS23410	COG0713	ATP synthesis coupled electron transport
N8I87_RS23415	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
N8I87_RS23425	COG1007	ATP synthesis coupled electron transport
N8I87_RS23430	COG0514	ATP-dependent DNA helicase (RecQ)
N8I87_RS23450	COG0492	ferredoxin-NADP+ reductase activity
N8I87_RS23460	COG0561	phosphatase activity
N8I87_RS23465	COG3953	SLT domain
N8I87_RS23465	COG5280	Phage tail tape measure protein TP901
N8I87_RS23475	COG0142	geranyltranstransferase activity
N8I87_RS23490	COG1131	(ABC) transporter
N8I87_RS23525	COG0702	epimerase
N8I87_RS23530	COG1733	regulation of RNA biosynthetic process
N8I87_RS23535	COG1013	pyruvate-flavodoxin oxidoreductase activity
N8I87_RS23540	COG0674	pyruvate-flavodoxin oxidoreductase activity
N8I87_RS23540	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
N8I87_RS23560	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
N8I87_RS23565	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
N8I87_RS23570	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
N8I87_RS23575	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
N8I87_RS23580	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
N8I87_RS23585	COG0839	Belongs to the complex I subunit 6 family
N8I87_RS23590	COG0713	ATP synthesis coupled electron transport
N8I87_RS23605	COG1007	ATP synthesis coupled electron transport
N8I87_RS23610	COG0501	Belongs to the peptidase M48B family
N8I87_RS23615	COG3304	Inner membrane component domain
N8I87_RS23625	COG2261	transglycosylase associated protein
N8I87_RS23630	COG1666	GTP binding
N8I87_RS23645	COG0702	epimerase
N8I87_RS23665	COG0267	Belongs to the bacterial ribosomal protein bL33 family
N8I87_RS23670	COG2030	dehydratase
N8I87_RS23690	COG0812	UDP-N-acetylmuramate dehydrogenase activity
N8I87_RS23700	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
N8I87_RS23705	COG0436	Aminotransferase
N8I87_RS23720	COG0250	Participates in transcription elongation, termination and antitermination
N8I87_RS23725	COG0582	viral genome integration into host DNA
N8I87_RS23745	COG2188	Transcriptional regulator
N8I87_RS23755	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
N8I87_RS23760	COG0081	regulation of translation
N8I87_RS23770	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
N8I87_RS23775	COG0222	ribosome binding
N8I87_RS23780	COG0085	RNA polymerase activity
N8I87_RS23785	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
N8I87_RS23815	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
N8I87_RS23820	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
N8I87_RS23825	COG0049	tRNA binding
N8I87_RS23830	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
N8I87_RS23840	COG3328	transposase activity
N8I87_RS23890	COG0051	transcription antitermination factor activity, RNA binding
N8I87_RS23895	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
N8I87_RS23900	COG0088	Forms part of the polypeptide exit tunnel
N8I87_RS23905	COG0089	rRNA binding
N8I87_RS23910	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
N8I87_RS23915	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
N8I87_RS23920	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
N8I87_RS23925	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
N8I87_RS23930	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
N8I87_RS23935	COG0255	Belongs to the universal ribosomal protein uL29 family
N8I87_RS23940	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
N8I87_RS23945	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
N8I87_RS23950	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
N8I87_RS23955	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
N8I87_RS23960	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
N8I87_RS23965	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
N8I87_RS23970	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
N8I87_RS23975	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
N8I87_RS23980	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
N8I87_RS23985	COG1841	ribosomal large subunit assembly
N8I87_RS23990	COG0200	Binds to the 23S rRNA
N8I87_RS24000	COG0563	adenylate kinase activity
N8I87_RS24010	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
N8I87_RS24015	COG0257	Belongs to the bacterial ribosomal protein bL36 family
N8I87_RS24020	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
N8I87_RS24025	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
N8I87_RS24030	COG0202	RNA polymerase activity
N8I87_RS24035	COG0203	ribosomal protein L17
N8I87_RS24040	COG0101	tRNA pseudouridine synthase activity
N8I87_RS24060	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
N8I87_RS24065	COG0463	Glycosyl transferase, family 2
N8I87_RS24080	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
N8I87_RS24085	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
N8I87_RS24090	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
N8I87_RS24095	COG1072	(Pantothenic acid kinase))
N8I87_RS24125	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
N8I87_RS24150	COG0736	holo-[acyl-carrier-protein] synthase activity
N8I87_RS24170	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N8I87_RS24175	COG0802	atpase or kinase
N8I87_RS24200	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
N8I87_RS24215	COG1472	Belongs to the glycosyl hydrolase 3 family
N8I87_RS24225	COG1175	transmembrane transport
N8I87_RS24230	COG1653	transport
N8I87_RS24235	COG1609	Transcriptional regulator
N8I87_RS24285	COG0726	polysaccharide deacetylase
N8I87_RS24290	COG0726	polysaccharide deacetylase
N8I87_RS24300	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
N8I87_RS24305	COG0459	protein refolding
N8I87_RS24315	COG1309	transcriptional regulator
N8I87_RS24325	COG4221	oxidoreductase activity
N8I87_RS24335	COG0583	DNA-binding transcription factor activity
N8I87_RS24350	COG1595	DNA-templated transcription, initiation
N8I87_RS24360	COG0516	GMP reductase activity
N8I87_RS24375	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
N8I87_RS24395	COG0515	serine threonine protein kinase
N8I87_RS24400	COG0515	serine threonine protein kinase
N8I87_RS24415	COG1012	belongs to the aldehyde dehydrogenase family
N8I87_RS24435	COG0519	Catalyzes the synthesis of GMP from XMP
N8I87_RS24435	COG0518	GMP synthase (glutamine-hydrolyzing) activity
N8I87_RS24485	COG2197	response regulator
N8I87_RS24540	COG0739	heme binding
N8I87_RS24550	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
N8I87_RS24550	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
N8I87_RS24565	COG0714	Associated with various cellular activities
N8I87_RS24570	COG2425	protein containing a von Willebrand factor type A (vWA) domain
N8I87_RS24575	COG3552	Protein containing von Willebrand factor type A (VWA) domain
N8I87_RS24590	COG0045	succinate-CoA ligase (ADP-forming) activity
N8I87_RS24620	COG0138	bifunctional purine biosynthesis protein purh
N8I87_RS24630	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
N8I87_RS24650	COG0039	L-malate dehydrogenase activity
N8I87_RS24660	COG1012	belongs to the aldehyde dehydrogenase family
N8I87_RS24670	COG4175	Glycine betaine
N8I87_RS24670	COG0517	IMP dehydrogenase activity
N8I87_RS24675	COG4176	ABC-type proline glycine betaine transport system permease component
N8I87_RS24690	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
N8I87_RS24695	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N8I87_RS24705	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
N8I87_RS24710	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
N8I87_RS24715	COG0180	Tryptophanyl-tRNA synthetase
N8I87_RS24750	COG1295	ribonuclease BN
N8I87_RS24755	COG1686	Belongs to the peptidase S11 family
N8I87_RS24875	COG2205	protein histidine kinase activity
N8I87_RS24880	COG0745	RESPONSE REGULATOR receiver
N8I87_RS24885	COG2409	Drug exporters of the RND superfamily
N8I87_RS24895	COG1309	transcriptional regulator
N8I87_RS24920	COG1053	succinate dehydrogenase
N8I87_RS24930	COG2009	succinate dehydrogenase
N8I87_RS24940	COG3525	Glycosyl hydrolase, family 20, catalytic domain
N8I87_RS24995	COG1595	DNA-templated transcription, initiation
N8I87_RS25010	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
N8I87_RS25010	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
N8I87_RS25020	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
N8I87_RS25030	COG1216	Glycosyl transferase, family 2
N8I87_RS25045	COG2089	acid synthase
N8I87_RS25060	COG1473	amidohydrolase
N8I87_RS25060	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
N8I87_RS25065	COG1744	ABC transporter substrate-binding protein PnrA-like
N8I87_RS25070	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
N8I87_RS25105	COG1744	ABC transporter substrate-binding protein PnrA-like
N8I87_RS25110	COG3845	ABC transporter
N8I87_RS25115	COG4603	Belongs to the binding-protein-dependent transport system permease family
N8I87_RS25120	COG1079	Belongs to the binding-protein-dependent transport system permease family
N8I87_RS25150	COG2814	Major facilitator Superfamily
N8I87_RS25155	COG0583	DNA-binding transcription factor activity
N8I87_RS25165	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
N8I87_RS25190	COG2205	protein histidine kinase activity
N8I87_RS25195	COG0745	RESPONSE REGULATOR receiver
N8I87_RS25200	COG1595	DNA-templated transcription, initiation
N8I87_RS25215	COG1012	belongs to the aldehyde dehydrogenase family
N8I87_RS25220	COG1012	belongs to the aldehyde dehydrogenase family
N8I87_RS25225	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
N8I87_RS25240	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
N8I87_RS25270	COG4770	biotin carboxylase activity
N8I87_RS25280	COG0424	maF-like protein
N8I87_RS25295	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
N8I87_RS25305	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
N8I87_RS25315	COG1024	Enoyl-CoA hydratase
N8I87_RS25325	COG2986	histidine ammonia-lyase
N8I87_RS25355	COG1136	(ABC) transporter
N8I87_RS25360	COG1404	Belongs to the peptidase S8 family
N8I87_RS25375	COG1064	alcohol dehydrogenase
N8I87_RS25385	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
N8I87_RS25475	COG2255	four-way junction helicase activity
N8I87_RS25480	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
N8I87_RS25495	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
N8I87_RS25505	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
N8I87_RS25525	COG1331	Highly conserved protein containing a thioredoxin domain
N8I87_RS25555	COG1309	transcriptional regulator
N8I87_RS25560	COG0477	Major facilitator Superfamily
N8I87_RS25570	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
N8I87_RS25580	COG0463	Glycosyl transferase, family 2
N8I87_RS25635	COG0436	Aminotransferase
N8I87_RS25655	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
N8I87_RS25670	COG1414	Transcriptional regulator
N8I87_RS25680	COG0251	oxidation-reduction process
N8I87_RS25715	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
N8I87_RS25755	COG2894	cell division
N8I87_RS25790	COG2197	response regulator
N8I87_RS25845	COG2318	DinB family
N8I87_RS25855	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
N8I87_RS25860	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
N8I87_RS25865	COG0741	lytic transglycosylase activity
N8I87_RS25875	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
N8I87_RS25880	COG0450	alkyl hydroperoxide reductase
N8I87_RS25910	COG1136	(ABC) transporter
N8I87_RS25935	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
N8I87_RS25950	COG0114	fumarate hydratase activity
N8I87_RS25955	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
N8I87_RS25955	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
N8I87_RS25980	COG0778	Nitroreductase
N8I87_RS25985	COG1722	exodeoxyribonuclease VII activity
N8I87_RS25990	COG1570	exodeoxyribonuclease VII activity
N8I87_RS25995	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
N8I87_RS26010	COG0012	GTP binding
N8I87_RS26025	COG0542	response to heat
N8I87_RS26130	COG1053	succinate dehydrogenase
N8I87_RS26150	COG1217	gtp-binding protein TYPA
N8I87_RS26155	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N8I87_RS26160	COG4166	transmembrane transport
N8I87_RS26165	COG0601	transmembrane transport
N8I87_RS26170	COG0444	Belongs to the ABC transporter superfamily
N8I87_RS26175	COG4608	Belongs to the ABC transporter superfamily
N8I87_RS26180	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
N8I87_RS26180	COG2813	Specifically methylates the guanine in position
N8I87_RS26185	COG4166	transmembrane transport
N8I87_RS26190	COG0601	transmembrane transport
N8I87_RS26195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N8I87_RS26205	COG4608	Belongs to the ABC transporter superfamily
N8I87_RS26220	COG0601	transmembrane transport
N8I87_RS26225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N8I87_RS26230	COG0444	Belongs to the ABC transporter superfamily
N8I87_RS26235	COG4608	Belongs to the ABC transporter superfamily
N8I87_RS26270	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
N8I87_RS26290	COG1131	(ABC) transporter
N8I87_RS26300	COG4585	Histidine kinase
N8I87_RS26305	COG2197	response regulator
N8I87_RS26340	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N8I87_RS26345	COG1611	Belongs to the LOG family
N8I87_RS26360	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
N8I87_RS26370	COG0519	Catalyzes the synthesis of GMP from XMP
N8I87_RS26375	COG1024	Enoyl-CoA hydratase
N8I87_RS26390	COG1595	DNA-templated transcription, initiation
N8I87_RS26400	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N8I87_RS26405	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
N8I87_RS26425	COG2239	Acts as a magnesium transporter
N8I87_RS26430	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
N8I87_RS26440	COG0598	Magnesium transport protein CorA
N8I87_RS26465	COG2095	MarC family integral membrane protein
N8I87_RS26475	COG1432	Conserved Protein
N8I87_RS26580	COG0210	DNA helicase
N8I87_RS26585	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N8I87_RS26625	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
N8I87_RS26675	COG3480	Lon protease (S16) C-terminal proteolytic domain
N8I87_RS26685	COG1615	UPF0182 protein
N8I87_RS26710	COG0753	catalase activity
N8I87_RS26720	COG0483	inositol monophosphate 1-phosphatase activity
N8I87_RS26740	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
N8I87_RS26770	COG2135	peptidase activity
N8I87_RS26780	COG1595	DNA-templated transcription, initiation
N8I87_RS26785	COG5662	AntiSigma factor
N8I87_RS26790	COG2199	diguanylate cyclase activity
N8I87_RS26790	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
N8I87_RS26805	COG0242	peptide deformylase activity
N8I87_RS26815	COG2124	cytochrome p450
N8I87_RS26820	COG4977	sequence-specific DNA binding
N8I87_RS26830	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
N8I87_RS26835	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
N8I87_RS26835	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
N8I87_RS26855	COG2188	Transcriptional regulator
N8I87_RS26860	COG2182	Extracellular solute-binding protein
N8I87_RS26865	COG1175	transmembrane transport
N8I87_RS26870	COG0395	ABC-type sugar transport system, permease component
N8I87_RS26875	COG1472	Belongs to the glycosyl hydrolase 3 family
N8I87_RS26880	COG0363	glucosamine-6-phosphate deaminase activity
N8I87_RS26895	COG1309	transcriptional regulator
N8I87_RS26910	COG1597	lipid kinase activity
N8I87_RS26940	COG2515	1-aminocyclopropane-1-carboxylate deaminase
N8I87_RS26950	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
N8I87_RS26960	COG0456	acetyltransferase
N8I87_RS26985	COG4941	Belongs to the sigma-70 factor family
N8I87_RS27000	COG0542	response to heat
N8I87_RS27080	COG0582	viral genome integration into host DNA
N8I87_RS27100	COG4106	trans-aconitate 2-methyltransferase activity
N8I87_RS27110	COG0765	amino acid transport
N8I87_RS27120	COG0281	malic enzyme
N8I87_RS27125	COG0604	alcohol dehydrogenase
N8I87_RS27205	COG2205	protein histidine kinase activity
N8I87_RS27210	COG0745	RESPONSE REGULATOR receiver
N8I87_RS27225	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
N8I87_RS27290	COG0791	NLP P60 protein
N8I87_RS27335	COG0772	Belongs to the SEDS family
N8I87_RS27340	COG2205	protein histidine kinase activity
N8I87_RS27360	COG1793	dna ligase
N8I87_RS27360	COG3285	dna ligase
N8I87_RS27365	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
N8I87_RS27465	COG3547	Transposase (IS116 IS110 IS902 family)
N8I87_RS27495	COG1132	(ABC) transporter
N8I87_RS27500	COG3629	intracellular signal transduction
N8I87_RS27500	COG3903	Transcriptional regulator
N8I87_RS27635	COG0018	arginyl-trna synthetase
N8I87_RS27640	COG0019	diaminopimelate decarboxylase activity
N8I87_RS27645	COG0460	homoserine dehydrogenase
N8I87_RS27650	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
N8I87_RS27655	COG0083	homoserine kinase activity
N8I87_RS27670	COG1316	TRANSCRIPTIONal
N8I87_RS27675	COG0254	rRNA binding
N8I87_RS27680	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
N8I87_RS27685	COG2890	protein-(glutamine-N5) methyltransferase activity
N8I87_RS27695	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
N8I87_RS27700	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
N8I87_RS27705	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
N8I87_RS27720	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
N8I87_RS27725	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
N8I87_RS27730	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
N8I87_RS27735	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
N8I87_RS27740	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
N8I87_RS27745	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
N8I87_RS27750	COG0355	proton-transporting ATP synthase activity, rotational mechanism
N8I87_RS27765	COG2197	response regulator
N8I87_RS27770	COG4585	Histidine kinase
N8I87_RS27800	COG1250	3-hydroxyacyl-CoA dehydrogenase
N8I87_RS27815	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
N8I87_RS27850	COG1131	(ABC) transporter
N8I87_RS27870	COG0183	Belongs to the thiolase family
N8I87_RS27965	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
N8I87_RS27965	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
N8I87_RS28000	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
N8I87_RS28005	COG0857	belongs to the CobB CobQ family
N8I87_RS28005	COG0280	phosphate acetyltransferase
N8I87_RS28010	COG0205	6-phosphofructokinase activity
N8I87_RS28020	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
N8I87_RS28030	COG4565	transcriptional regulatory protein
N8I87_RS28035	COG3290	protein histidine kinase activity
N8I87_RS28040	COG1301	dicarboxylic acid transport
N8I87_RS28050	COG0477	Major facilitator Superfamily
N8I87_RS28080	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
N8I87_RS28085	COG0789	Transcriptional regulator
N8I87_RS28100	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
N8I87_RS28105	COG3281	Trehalose synthase
N8I87_RS28125	COG0058	SHG alpha-glucan phosphorylase activity
N8I87_RS28155	COG1132	(ABC) transporter
N8I87_RS28160	COG1132	(ABC) transporter
N8I87_RS28165	COG1132	(ABC) transporter
N8I87_RS28180	COG1376	ErfK ybiS ycfS ynhG family protein
N8I87_RS28185	COG1376	ErfK ybiS ycfS ynhG family protein
N8I87_RS28215	COG0789	Transcriptional regulator
N8I87_RS28225	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
N8I87_RS28230	COG3525	Glycosyl hydrolase, family 20, catalytic domain
N8I87_RS28275	COG3409	Peptidoglycan-binding domain 1 protein
N8I87_RS28275	COG3757	hydrolase, family 25
N8I87_RS28285	COG1760	l-serine dehydratase
N8I87_RS28290	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
N8I87_RS28295	COG0509	glycine decarboxylation via glycine cleavage system
N8I87_RS28300	COG0404	The glycine cleavage system catalyzes the degradation of glycine
N8I87_RS28320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N8I87_RS28325	COG4166	transmembrane transport
N8I87_RS28335	COG0444	Belongs to the ABC transporter superfamily
N8I87_RS28340	COG4608	Belongs to the ABC transporter superfamily
N8I87_RS28350	COG2860	membrane
N8I87_RS28370	COG2378	regulation of single-species biofilm formation
N8I87_RS28410	COG0482	sulfurtransferase activity
N8I87_RS28425	COG1611	Belongs to the LOG family
N8I87_RS28430	COG4221	oxidoreductase activity
N8I87_RS28445	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
N8I87_RS28460	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
N8I87_RS28465	COG0154	amidase activity
N8I87_RS28475	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
N8I87_RS28480	COG2226	methyltransferase
N8I87_RS28490	COG2409	Drug exporters of the RND superfamily
N8I87_RS28495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N8I87_RS28515	COG2197	response regulator
N8I87_RS28525	COG2133	pyrroloquinoline quinone binding
N8I87_RS28530	COG0667	Aldo Keto reductase
N8I87_RS28540	COG5001	Diguanylate cyclase
N8I87_RS28550	COG0440	acetolactate synthase activity
N8I87_RS28555	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
N8I87_RS28560	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
N8I87_RS28565	COG0477	Major facilitator Superfamily
N8I87_RS28575	COG3835	regulator
N8I87_RS28580	COG0506	proline dehydrogenase activity
N8I87_RS28585	COG1012	belongs to the aldehyde dehydrogenase family
N8I87_RS28605	COG0473	3-isopropylmalate dehydrogenase activity
N8I87_RS28610	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
N8I87_RS28615	COG0832	Belongs to the urease beta subunit family
N8I87_RS28615	COG0831	urea catabolic process
N8I87_RS28620	COG0804	urea catabolic process
N8I87_RS28625	COG2957	Belongs to the agmatine deiminase family
N8I87_RS28635	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
N8I87_RS28650	COG1472	Belongs to the glycosyl hydrolase 3 family
N8I87_RS28705	COG5492	domain, Protein
N8I87_RS28710	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
N8I87_RS28730	COG2018	Roadblock/LC7 domain
N8I87_RS28750	COG2018	Roadblock/LC7 domain
N8I87_RS28765	COG0179	Fumarylacetoacetate (FAA) hydrolase
N8I87_RS28770	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
N8I87_RS28820	COG1414	Transcriptional regulator
N8I87_RS28825	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
N8I87_RS28830	COG0066	3-isopropylmalate dehydratase activity
N8I87_RS28840	COG0776	regulation of translation
N8I87_RS28850	COG1920	GTP binding
N8I87_RS28860	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
N8I87_RS28865	COG1181	Belongs to the D-alanine--D-alanine ligase family
N8I87_RS28885	COG0351	phosphomethylpyrimidine kinase
N8I87_RS28890	COG0227	Belongs to the bacterial ribosomal protein bL28 family
N8I87_RS28895	COG1461	Dihydroxyacetone kinase
N8I87_RS28905	COG0326	Molecular chaperone. Has ATPase activity
N8I87_RS28915	COG0742	ribosomal rna small subunit methyltransferase
N8I87_RS28920	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
N8I87_RS28935	COG0333	Belongs to the bacterial ribosomal protein bL32 family
N8I87_RS28940	COG0571	ribonuclease III activity
N8I87_RS28945	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
N8I87_RS28950	COG1733	regulation of RNA biosynthetic process
N8I87_RS28955	COG0655	NAD(P)H dehydrogenase (quinone) activity
N8I87_RS28965	COG1254	Belongs to the acylphosphatase family
N8I87_RS28975	COG1196	nuclear chromosome segregation
N8I87_RS28980	COG0477	Major facilitator Superfamily
N8I87_RS29035	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
N8I87_RS29045	COG0442	prolyl-tRNA aminoacylation
N8I87_RS29055	COG0228	four-way junction DNA binding
N8I87_RS29060	COG1837	Belongs to the UPF0109 family
N8I87_RS29065	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
N8I87_RS29070	COG0336	Belongs to the RNA methyltransferase TrmD family
N8I87_RS29075	COG0335	large ribosomal subunit rRNA binding
N8I87_RS29085	COG0681	Belongs to the peptidase S26 family
N8I87_RS29100	COG1051	belongs to the nudix hydrolase family
N8I87_RS29110	COG0792	nuclease activity
N8I87_RS29125	COG1191	sigma factor activity
N8I87_RS29140	COG0052	Belongs to the universal ribosomal protein uS2 family
N8I87_RS29145	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
N8I87_RS29150	COG0528	UMP kinase activity
N8I87_RS29155	COG0233	cytoplasmic translational termination
N8I87_RS29160	COG0575	Belongs to the CDS family
N8I87_RS29165	COG0820	rRNA (adenine-C2-)-methyltransferase activity
N8I87_RS29175	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
N8I87_RS29180	COG3842	ATPase activity
N8I87_RS29205	COG1136	(ABC) transporter
N8I87_RS29210	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
N8I87_RS29220	COG1012	belongs to the aldehyde dehydrogenase family
N8I87_RS29255	COG2205	protein histidine kinase activity
N8I87_RS29265	COG0745	RESPONSE REGULATOR receiver
N8I87_RS29290	COG0390	transport system, permease component
N8I87_RS29305	COG1309	transcriptional regulator
N8I87_RS29320	COG4585	Histidine kinase
N8I87_RS29325	COG2197	response regulator
N8I87_RS29365	COG0584	glycerophosphoryl diester phosphodiesterase
N8I87_RS29370	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
N8I87_RS29395	COG3842	ATPase activity
N8I87_RS29400	COG1176	ABC-type spermidine putrescine transport system, permease component I
N8I87_RS29405	COG1177	transmembrane transport
N8I87_RS29410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N8I87_RS29435	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
N8I87_RS29455	COG2508	Transcriptional regulator
N8I87_RS29460	COG1012	belongs to the aldehyde dehydrogenase family
N8I87_RS29480	COG5297	Belongs to the glycosyl hydrolase family 6
N8I87_RS29495	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
N8I87_RS29500	COG0750	zinc metalloprotease
N8I87_RS29505	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
N8I87_RS29520	COG0442	prolyl-tRNA aminoacylation
N8I87_RS29540	COG0779	Required for maturation of 30S ribosomal subunits
N8I87_RS29555	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
N8I87_RS29565	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
N8I87_RS29570	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
N8I87_RS29600	COG3266	domain, Protein
N8I87_RS29605	COG1404	Belongs to the peptidase S8 family
N8I87_RS29620	COG1404	Belongs to the peptidase S8 family
N8I87_RS29665	COG1674	ftsk spoiiie
N8I87_RS29690	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
N8I87_RS29695	COG1185	polyribonucleotide nucleotidyltransferase activity
N8I87_RS29700	COG0612	Peptidase, M16
N8I87_RS29705	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
N8I87_RS29725	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
N8I87_RS29730	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N8I87_RS29735	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
N8I87_RS29765	COG2208	phosphoserine phosphatase activity
N8I87_RS29765	COG2770	Histidine kinase
N8I87_RS29770	COG0784	Response regulator, receiver
N8I87_RS29770	COG2205	protein histidine kinase activity
N8I87_RS29780	COG1674	ftsk spoiiie
N8I87_RS29790	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
N8I87_RS29800	COG1058	Belongs to the CinA family
N8I87_RS29800	COG1546	Belongs to the CinA family
N8I87_RS29805	COG1396	sequence-specific DNA binding
N8I87_RS29820	COG1028	Short-chain dehydrogenase reductase Sdr
N8I87_RS29825	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
N8I87_RS29830	COG1201	RNA secondary structure unwinding
N8I87_RS29835	COG2207	Transcriptional regulator
N8I87_RS29860	COG0628	permease
N8I87_RS29870	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
N8I87_RS29905	COG0765	amino acid transport
N8I87_RS29910	COG0765	amino acid transport
N8I87_RS29915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N8I87_RS29920	COG1126	abc transporter atp-binding protein
N8I87_RS29925	COG0745	RESPONSE REGULATOR receiver
N8I87_RS29930	COG2205	protein histidine kinase activity
N8I87_RS29935	COG2358	TRAP transporter, solute receptor (TAXI family
N8I87_RS29955	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
N8I87_RS29975	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
N8I87_RS29985	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
N8I87_RS29990	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
N8I87_RS30000	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
N8I87_RS30035	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
N8I87_RS30040	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
N8I87_RS30045	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
N8I87_RS30060	COG0588	phosphoglycerate mutase activity
N8I87_RS30080	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
N8I87_RS30095	COG0514	ATP-dependent DNA helicase (RecQ)
N8I87_RS30120	COG1802	Transcriptional regulator
N8I87_RS30125	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
N8I87_RS30140	COG0187	DNA topoisomerase II activity
N8I87_RS30155	COG2197	response regulator
N8I87_RS30165	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N8I87_RS30190	COG0372	Belongs to the citrate synthase family
N8I87_RS30210	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
N8I87_RS30215	COG0612	Peptidase, M16
N8I87_RS30230	COG1802	Transcriptional regulator
N8I87_RS30235	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
N8I87_RS30240	COG0045	succinate-CoA ligase (ADP-forming) activity
N8I87_RS30240	COG1042	CoA-binding domain protein
N8I87_RS30240	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N8I87_RS30260	COG1435	thymidine kinase activity
N8I87_RS30290	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
N8I87_RS30305	COG0745	RESPONSE REGULATOR receiver
N8I87_RS30310	COG2205	protein histidine kinase activity
N8I87_RS30335	COG0756	dUTP diphosphatase activity
N8I87_RS30380	COG0569	domain protein
N8I87_RS30390	COG0531	amino acid
N8I87_RS30395	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
N8I87_RS30400	COG0009	L-threonylcarbamoyladenylate synthase
N8I87_RS30465	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
N8I87_RS30475	COG2409	Drug exporters of the RND superfamily
N8I87_RS30490	COG0142	geranyltranstransferase activity
N8I87_RS30550	COG1131	(ABC) transporter
N8I87_RS30610	COG2814	Major facilitator Superfamily
N8I87_RS30625	COG4044	May play a role in the intracellular transport of hydrophobic ligands
N8I87_RS30650	COG0300	oxidoreductase activity
N8I87_RS30650	COG1028	Short-chain dehydrogenase reductase Sdr
N8I87_RS30650	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N8I87_RS30650	COG0318	PFAM AMP-dependent synthetase and ligase
N8I87_RS30650	COG3321	synthase
N8I87_RS30660	COG0300	oxidoreductase activity
N8I87_RS30675	COG2124	cytochrome p450
N8I87_RS30695	COG0235	Class ii aldolase
N8I87_RS30695	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
N8I87_RS30700	COG0235	Class ii aldolase
N8I87_RS30705	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
N8I87_RS30710	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
N8I87_RS30720	COG4221	oxidoreductase activity
N8I87_RS30720	COG3321	synthase
N8I87_RS30720	COG0300	oxidoreductase activity
N8I87_RS30720	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
N8I87_RS30725	COG1104	cysteine desulfurase activity
N8I87_RS30740	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
N8I87_RS30750	COG4585	Histidine kinase
N8I87_RS30755	COG1131	(ABC) transporter
N8I87_RS30765	COG2197	response regulator
N8I87_RS30770	COG0318	PFAM AMP-dependent synthetase and ligase
N8I87_RS30790	COG0604	alcohol dehydrogenase
N8I87_RS30790	COG3321	synthase
N8I87_RS30795	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
N8I87_RS30830	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
N8I87_RS30840	COG3251	PFAM MbtH domain protein
N8I87_RS30865	COG0318	PFAM AMP-dependent synthetase and ligase
N8I87_RS30875	COG3629	intracellular signal transduction
N8I87_RS30875	COG3903	Transcriptional regulator
N8I87_RS30900	COG0154	amidase activity
N8I87_RS30915	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N8I87_RS30925	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
N8I87_RS30940	COG3321	synthase
N8I87_RS30940	COG0604	alcohol dehydrogenase
N8I87_RS30960	COG1131	(ABC) transporter
N8I87_RS30970	COG2267	carboxylic ester hydrolase activity
N8I87_RS30980	COG3321	synthase
N8I87_RS30980	COG0604	alcohol dehydrogenase
N8I87_RS30990	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N8I87_RS31005	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
N8I87_RS31015	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
N8I87_RS31025	COG1410	methionine synthase
N8I87_RS31025	COG0646	methionine synthase
N8I87_RS31070	COG1799	cell septum assembly
N8I87_RS31100	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
N8I87_RS31135	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
N8I87_RS31140	COG0531	amino acid
N8I87_RS31150	COG1024	Enoyl-CoA hydratase
N8I87_RS31190	COG2801	Transposase and inactivated derivatives
N8I87_RS31190	COG3415	Transposase
N8I87_RS31230	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
N8I87_RS31235	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
N8I87_RS31250	COG3537	Alpha-1,2-mannosidase
N8I87_RS31260	COG3629	intracellular signal transduction
N8I87_RS31260	COG3903	Transcriptional regulator
N8I87_RS31270	COG1653	transport
N8I87_RS31275	COG1175	transmembrane transport
N8I87_RS31280	COG0395	ABC-type sugar transport system, permease component
N8I87_RS31285	COG1940	carbohydrate kinase activity
N8I87_RS31290	COG4213	ABC transporter substrate-binding protein
N8I87_RS31300	COG4214	carbohydrate transport
N8I87_RS31305	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
N8I87_RS31310	COG0531	amino acid
N8I87_RS31335	COG1250	3-hydroxyacyl-CoA dehydrogenase
N8I87_RS31335	COG1024	Enoyl-CoA hydratase
N8I87_RS31340	COG0183	Belongs to the thiolase family
N8I87_RS31345	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
N8I87_RS31360	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
N8I87_RS31375	COG0446	pyridine nucleotide-disulphide oxidoreductase
N8I87_RS31390	COG3253	May function as heme-dependent peroxidase
N8I87_RS31410	COG3220	belongs to the UPF0276 family
N8I87_RS31420	COG1116	anion transmembrane transporter activity
N8I87_RS31440	COG1881	PFAM PEBP family protein
N8I87_RS31445	COG0330	HflC and HflK could
N8I87_RS31465	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
N8I87_RS31470	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
N8I87_RS31480	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
N8I87_RS31485	COG1113	amino acid transport
N8I87_RS31515	COG1174	glycine betaine transport
N8I87_RS31520	COG1174	glycine betaine transport
N8I87_RS31535	COG2018	Roadblock/LC7 domain
N8I87_RS31545	COG1732	Glycine betaine
N8I87_RS31550	COG2986	histidine ammonia-lyase
N8I87_RS31560	COG3340	Belongs to the peptidase S51 family
N8I87_RS31585	COG1309	transcriptional regulator
N8I87_RS31695	COG2409	Drug exporters of the RND superfamily
N8I87_RS31740	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N8I87_RS31745	COG1116	anion transmembrane transporter activity
N8I87_RS31765	COG0529	Catalyzes the synthesis of activated sulfate
N8I87_RS31770	COG0175	sulfate reduction
N8I87_RS31800	COG1960	acyl-CoA dehydrogenase activity
N8I87_RS31810	COG0702	epimerase
N8I87_RS31815	COG1917	Cupin 2, conserved barrel domain protein
N8I87_RS31815	COG4977	sequence-specific DNA binding
N8I87_RS31835	COG1476	TRANSCRIPTIONal
N8I87_RS31870	COG0477	Major facilitator Superfamily
N8I87_RS31875	COG1309	transcriptional regulator
N8I87_RS31890	COG2040	homocysteine
N8I87_RS31950	COG1175	transmembrane transport
N8I87_RS31975	COG0277	FAD linked oxidase domain protein
N8I87_RS32030	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
N8I87_RS32060	COG1278	Cold shock
N8I87_RS32065	COG1162	GTPase activity
N8I87_RS32075	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
N8I87_RS32100	COG0028	Belongs to the TPP enzyme family
N8I87_RS32120	COG1802	Transcriptional regulator
N8I87_RS32150	COG1529	Aldehyde oxidase and xanthine dehydrogenase
N8I87_RS32155	COG2252	PERMEase
N8I87_RS32170	COG2124	cytochrome p450
N8I87_RS32195	COG0515	serine threonine protein kinase
N8I87_RS32210	COG1653	transport
N8I87_RS32215	COG0598	Magnesium transport protein CorA
N8I87_RS32245	COG2197	response regulator
N8I87_RS32250	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
N8I87_RS32255	COG0318	PFAM AMP-dependent synthetase and ligase
N8I87_RS32265	COG3960	tartronate-semialdehyde synthase activity
N8I87_RS32280	COG2084	Dehydrogenase
N8I87_RS32285	COG3622	Belongs to the hyi family
N8I87_RS32305	COG2351	hydroxyisourate hydrolase activity
N8I87_RS32330	COG0406	alpha-ribazole phosphatase activity
N8I87_RS32335	COG0436	Aminotransferase
N8I87_RS32355	COG4264	IucA IucC family
N8I87_RS32375	COG2508	Transcriptional regulator
N8I87_RS32380	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N8I87_RS32395	COG0318	PFAM AMP-dependent synthetase and ligase
N8I87_RS32405	COG2197	response regulator
N8I87_RS32420	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
N8I87_RS32435	COG1414	Transcriptional regulator
N8I87_RS32440	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
N8I87_RS32445	COG4266	Belongs to the allantoicase family
N8I87_RS32470	COG2197	response regulator
N8I87_RS32490	COG0673	inositol 2-dehydrogenase activity
N8I87_RS32495	COG2188	Transcriptional regulator
N8I87_RS32500	COG1940	carbohydrate kinase activity
N8I87_RS32510	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
N8I87_RS32530	COG3903	Transcriptional regulator
N8I87_RS32530	COG3629	intracellular signal transduction
N8I87_RS32575	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N8I87_RS32630	COG0300	oxidoreductase activity
N8I87_RS32635	COG3387	PFAM Glycoside hydrolase 15-related
N8I87_RS32645	COG0028	Belongs to the TPP enzyme family
N8I87_RS32650	COG0277	FAD linked oxidase domain protein
N8I87_RS32650	COG0247	lactate metabolic process
N8I87_RS32695	COG2264	protein methyltransferase activity
N8I87_RS32715	COG0243	molybdopterin cofactor binding
N8I87_RS32735	COG0723	plastoquinol--plastocyanin reductase activity
N8I87_RS32735	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N8I87_RS32740	COG0546	phosphoglycolate phosphatase activity
N8I87_RS32745	COG1335	isochorismatase
N8I87_RS32750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N8I87_RS32805	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
N8I87_RS32810	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
N8I87_RS32815	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
N8I87_RS32845	COG1278	Cold shock
N8I87_RS32850	COG0513	Belongs to the DEAD box helicase family
N8I87_RS32875	COG1278	Cold shock
N8I87_RS32880	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
N8I87_RS32895	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
N8I87_RS32910	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
N8I87_RS32915	COG2072	flavoprotein involved in K transport
N8I87_RS32925	COG1247	-acetyltransferase
N8I87_RS32930	COG0640	Transcriptional regulator
N8I87_RS33025	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
N8I87_RS33030	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
N8I87_RS33065	COG0405	Gamma-glutamyltransferase
N8I87_RS33070	COG0542	response to heat
N8I87_RS33095	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
N8I87_RS33110	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
N8I87_RS33120	COG1953	Uracil, thiamine, allantoin
N8I87_RS33150	COG1012	belongs to the aldehyde dehydrogenase family
N8I87_RS33160	COG0483	inositol monophosphate 1-phosphatase activity
N8I87_RS33175	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
N8I87_RS33220	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
N8I87_RS33265	COG1278	Cold shock
N8I87_RS33275	COG0513	Belongs to the DEAD box helicase family
N8I87_RS33305	COG1929	Belongs to the glycerate kinase type-1 family
N8I87_RS33315	COG0688	phosphatidylethanolamine metabolic process
N8I87_RS33320	COG1960	acyl-CoA dehydrogenase activity
N8I87_RS33335	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
N8I87_RS33335	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
N8I87_RS33340	COG0604	alcohol dehydrogenase
N8I87_RS33350	COG1250	3-hydroxyacyl-CoA dehydrogenase
N8I87_RS33365	COG0596	Alpha beta hydrolase
N8I87_RS33385	COG2172	sigma factor antagonist activity
N8I87_RS33385	COG2208	phosphoserine phosphatase activity
N8I87_RS33385	COG1366	Belongs to the anti-sigma-factor antagonist family
N8I87_RS33390	COG4106	trans-aconitate 2-methyltransferase activity
N8I87_RS33395	COG2362	D-Aminopeptidase
N8I87_RS33400	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N8I87_RS33410	COG1619	proteins homologs of microcin C7 resistance protein MccF
N8I87_RS33445	COG3959	Transketolase, thiamine diphosphate binding domain
N8I87_RS33520	COG0406	alpha-ribazole phosphatase activity
N8I87_RS33525	COG0488	(ABC) transporter
N8I87_RS33535	COG0693	protein deglycase activity
N8I87_RS33605	COG0443	Heat shock 70 kDa protein
N8I87_RS33635	COG2154	pterin-4-alpha-carbinolamine dehydratase
N8I87_RS33640	COG2226	methyltransferase
N8I87_RS33655	COG2378	regulation of single-species biofilm formation
N8I87_RS33665	COG5297	Belongs to the glycosyl hydrolase family 6
N8I87_RS33665	COG4733	cellulase activity
N8I87_RS33670	COG5297	Belongs to the glycosyl hydrolase family 6
N8I87_RS33675	COG5297	Belongs to the glycosyl hydrolase family 6
N8I87_RS33710	COG0656	L-ascorbic acid biosynthetic process
N8I87_RS33720	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
N8I87_RS33735	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
N8I87_RS33745	COG3469	chitinase activity
N8I87_RS33750	COG3250	beta-galactosidase activity
N8I87_RS33780	COG1335	isochorismatase
N8I87_RS33785	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
N8I87_RS33790	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
N8I87_RS33795	COG1012	belongs to the aldehyde dehydrogenase family
N8I87_RS33815	COG0596	Alpha beta hydrolase
N8I87_RS33820	COG0183	Belongs to the thiolase family
N8I87_RS33825	COG1011	Hydrolase
N8I87_RS33830	COG0318	PFAM AMP-dependent synthetase and ligase
N8I87_RS33840	COG1309	transcriptional regulator
N8I87_RS33845	COG1028	Short-chain dehydrogenase reductase Sdr
N8I87_RS33850	COG1024	Enoyl-CoA hydratase
N8I87_RS33855	COG1960	acyl-CoA dehydrogenase activity
N8I87_RS33880	COG1946	Acyl-CoA thioesterase
N8I87_RS33885	COG1250	3-hydroxyacyl-CoA dehydrogenase
N8I87_RS33885	COG1024	Enoyl-CoA hydratase
N8I87_RS33890	COG2130	NADP-dependent
N8I87_RS33920	COG1376	ErfK ybiS ycfS ynhG family protein
N8I87_RS33950	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
N8I87_RS33960	COG2182	Extracellular solute-binding protein
N8I87_RS33965	COG1175	transmembrane transport
N8I87_RS33970	COG0395	ABC-type sugar transport system, permease component
N8I87_RS33975	COG2723	6-phospho-beta-galactosidase activity
N8I87_RS33990	COG0210	DNA helicase
N8I87_RS34005	COG4245	von Willebrand factor, type A
N8I87_RS34030	COG1401	restriction endodeoxyribonuclease activity
N8I87_RS34050	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
N8I87_RS34060	COG2815	serine threonine protein kinase
N8I87_RS34060	COG0515	serine threonine protein kinase
N8I87_RS34110	COG0297	glycogen (starch) synthase activity
N8I87_RS34130	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
N8I87_RS34150	COG3467	pyridoxamine 5'-phosphate
N8I87_RS34170	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
N8I87_RS34190	COG0789	Transcriptional regulator
N8I87_RS34240	COG1486	melibiose metabolic process
N8I87_RS34250	COG3469	chitinase activity
N8I87_RS34260	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
N8I87_RS34310	COG1175	transmembrane transport
N8I87_RS34315	COG0395	ABC-type sugar transport system, permease component
N8I87_RS34320	COG0366	Alpha amylase catalytic
N8I87_RS34340	COG3629	intracellular signal transduction
N8I87_RS34340	COG3903	Transcriptional regulator
N8I87_RS34405	COG3511	phospholipase C
N8I87_RS34435	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
N8I87_RS34440	COG0477	Major facilitator Superfamily
N8I87_RS34460	COG1793	dna ligase
N8I87_RS34535	COG1595	DNA-templated transcription, initiation
N8I87_RS34550	COG1834	amidinotransferase
N8I87_RS34555	COG0488	(ABC) transporter
N8I87_RS34590	COG3268	Saccharopine dehydrogenase
N8I87_RS34600	COG1804	L-carnitine dehydratase bile acid-inducible protein F
N8I87_RS34610	COG0183	Belongs to the thiolase family
N8I87_RS34615	COG1024	Enoyl-CoA hydratase
N8I87_RS34615	COG1250	3-hydroxyacyl-CoA dehydrogenase
N8I87_RS34640	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N8I87_RS34650	COG2936	dipeptidyl-peptidase activity
N8I87_RS34665	COG0488	(ABC) transporter
N8I87_RS34675	COG4977	sequence-specific DNA binding
N8I87_RS34685	COG1024	Enoyl-CoA hydratase
N8I87_RS34695	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
N8I87_RS34740	COG1134	teichoic acid transport
N8I87_RS34745	COG1562	ergosterol biosynthetic process
N8I87_RS34755	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
N8I87_RS34765	COG1657	PFAM Prenyltransferase squalene oxidase
N8I87_RS34780	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
N8I87_RS34785	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
N8I87_RS34805	COG2365	Tyrosine phosphatase family
N8I87_RS34820	COG2755	lipolytic protein G-D-S-L family
N8I87_RS34830	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
N8I87_RS34870	COG1063	alcohol dehydrogenase
N8I87_RS34875	COG0156	8-amino-7-oxononanoate synthase activity
N8I87_RS34880	COG0583	DNA-binding transcription factor activity
N8I87_RS34890	COG3958	Transketolase
N8I87_RS34895	COG3959	Transketolase, thiamine diphosphate binding domain
N8I87_RS34905	COG1309	transcriptional regulator
N8I87_RS34940	COG0561	phosphatase activity
N8I87_RS34950	COG2267	carboxylic ester hydrolase activity
N8I87_RS34955	COG0183	Belongs to the thiolase family
N8I87_RS34965	COG1011	Hydrolase
N8I87_RS34995	COG1234	tRNA 3'-trailer cleavage
N8I87_RS35015	COG0494	nUDIX hydrolase
N8I87_RS35030	COG0395	ABC-type sugar transport system, permease component
N8I87_RS35040	COG1653	transport
N8I87_RS35045	COG2188	Transcriptional regulator
N8I87_RS35050	COG3962	Belongs to the TPP enzyme family
N8I87_RS35090	COG0673	inositol 2-dehydrogenase activity
N8I87_RS35095	COG1028	Short-chain dehydrogenase reductase Sdr
N8I87_RS35110	COG1609	Transcriptional regulator
N8I87_RS35155	COG0142	geranyltranstransferase activity
N8I87_RS35170	COG3938	Belongs to the proline racemase family
N8I87_RS35190	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N8I87_RS35215	COG2197	response regulator
N8I87_RS35255	COG2838	Isocitrate dehydrogenase
N8I87_RS35260	COG0668	transmembrane transport
N8I87_RS35265	COG1024	Enoyl-CoA hydratase
N8I87_RS35275	COG1132	(ABC) transporter
N8I87_RS35305	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
N8I87_RS35320	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
N8I87_RS35340	COG0297	glycogen (starch) synthase activity
N8I87_RS35345	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
N8I87_RS35350	COG3537	Alpha-1,2-mannosidase
N8I87_RS35410	COG1609	Transcriptional regulator
N8I87_RS35420	COG1175	transmembrane transport
N8I87_RS35425	COG0395	ABC-type sugar transport system, permease component
N8I87_RS35450	COG2186	Transcriptional regulator
N8I87_RS35455	COG1879	ABC-type sugar transport system periplasmic component
N8I87_RS35460	COG1129	ABC transporter
N8I87_RS35470	COG4948	Mandelate Racemase Muconate Lactonizing
N8I87_RS35475	COG1028	Short-chain dehydrogenase reductase Sdr
N8I87_RS35510	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
N8I87_RS35535	COG0531	amino acid
N8I87_RS35555	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
N8I87_RS35555	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
N8I87_RS35560	COG0726	polysaccharide deacetylase
N8I87_RS35600	COG0583	DNA-binding transcription factor activity
N8I87_RS35610	COG1053	succinate dehydrogenase
N8I87_RS35615	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
N8I87_RS35645	COG0542	response to heat
N8I87_RS35650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N8I87_RS35660	COG3360	Dodecin
N8I87_RS35670	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
N8I87_RS35675	COG0121	glutamine amidotransferase
N8I87_RS35680	COG1262	PFAM Formylglycine-generating sulfatase enzyme
N8I87_RS35685	COG3572	ergothioneine biosynthetic process
N8I87_RS35700	COG2268	Band 7 protein
N8I87_RS35730	COG3903	Transcriptional regulator
N8I87_RS35730	COG3629	intracellular signal transduction
N8I87_RS35760	COG0243	molybdopterin cofactor binding
N8I87_RS35790	COG1609	Transcriptional regulator
N8I87_RS35795	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N8I87_RS35805	COG0242	peptide deformylase activity
N8I87_RS35840	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N8I87_RS35865	COG0604	alcohol dehydrogenase
N8I87_RS35880	COG0542	response to heat
N8I87_RS35890	COG1556	Lactate utilization protein
N8I87_RS35895	COG1139	Iron-sulfur cluster binding protein
N8I87_RS35900	COG0247	lactate metabolic process
N8I87_RS35905	COG1070	Carbohydrate kinase
N8I87_RS35910	COG1028	Short-chain dehydrogenase reductase Sdr
N8I87_RS35910	COG3347	Dehydrogenase
N8I87_RS35930	COG1609	Transcriptional regulator
N8I87_RS35945	COG1595	DNA-templated transcription, initiation
N8I87_RS35955	COG1357	PFAM Pentapeptide repeats (8 copies)
N8I87_RS35965	COG1309	transcriptional regulator
N8I87_RS35975	COG2706	6-phosphogluconolactonase activity
N8I87_RS36010	COG1796	DNA polymerase
N8I87_RS36010	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
N8I87_RS36045	COG2111	Na H antiporter
N8I87_RS36050	COG1006	Multisubunit Na H antiporter MnhC subunit
N8I87_RS36055	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
N8I87_RS36065	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
N8I87_RS36075	COG1366	Belongs to the anti-sigma-factor antagonist family
N8I87_RS36145	COG0435	Glutathione S-transferase
N8I87_RS36165	COG2124	cytochrome p450
N8I87_RS36185	COG0667	Aldo Keto reductase
N8I87_RS36210	COG1595	DNA-templated transcription, initiation
N8I87_RS36225	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
N8I87_RS36275	COG3832	glyoxalase III activity
N8I87_RS36325	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
N8I87_RS36335	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
N8I87_RS36395	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
N8I87_RS36455	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
N8I87_RS36480	COG1132	(ABC) transporter
N8I87_RS36485	COG1937	Protein conserved in bacteria
N8I87_RS36510	COG1028	Short-chain dehydrogenase reductase Sdr
N8I87_RS36620	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
N8I87_RS36655	COG2815	serine threonine protein kinase
N8I87_RS36655	COG0515	serine threonine protein kinase
N8I87_RS36660	COG0671	phosphoesterase, PA-phosphatase related
N8I87_RS36665	COG0671	phosphoesterase, PA-phosphatase related
N8I87_RS36670	COG0586	Pfam SNARE associated Golgi protein
N8I87_RS36700	COG3387	PFAM Glycoside hydrolase 15-related
N8I87_RS36735	COG3290	protein histidine kinase activity
N8I87_RS36750	COG2045	Belongs to the ComB family
N8I87_RS36810	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
N8I87_RS36870	COG0667	Aldo Keto reductase
N8I87_RS36875	COG2197	response regulator
N8I87_RS36890	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
N8I87_RS36920	COG0583	DNA-binding transcription factor activity
N8I87_RS36925	COG3291	Pkd domain containing protein
N8I87_RS36955	COG0745	RESPONSE REGULATOR receiver
N8I87_RS36960	COG5002	protein histidine kinase activity
N8I87_RS36995	COG2132	Multicopper oxidase
N8I87_RS37015	COG0701	Predicted permease
N8I87_RS37115	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
N8I87_RS37120	COG3864	Putative metallopeptidase domain
N8I87_RS37125	COG0714	Associated with various cellular activities
N8I87_RS37150	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
N8I87_RS37155	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
N8I87_RS37250	COG1414	Transcriptional regulator
N8I87_RS37255	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
N8I87_RS37280	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
N8I87_RS37295	COG1309	transcriptional regulator
N8I87_RS37310	COG1733	regulation of RNA biosynthetic process
N8I87_RS37315	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
N8I87_RS37330	COG0267	Belongs to the bacterial ribosomal protein bL33 family
N8I87_RS37400	COG2197	response regulator
N8I87_RS37425	COG0531	amino acid
N8I87_RS37480	COG0300	oxidoreductase activity
N8I87_RS37500	COG0137	argininosuccinate synthase activity
N8I87_RS37515	COG0277	FAD linked oxidase domain protein
N8I87_RS37520	COG1597	lipid kinase activity
N8I87_RS37525	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
N8I87_RS37535	COG0477	Major facilitator Superfamily
N8I87_RS37540	COG2175	clavaminate synthase activity
N8I87_RS37550	COG3246	L-lysine catabolic process to acetate
N8I87_RS37630	COG1132	(ABC) transporter
N8I87_RS37640	COG1309	transcriptional regulator
N8I87_RS37645	COG2409	Drug exporters of the RND superfamily
N8I87_RS37680	COG2755	lipolytic protein G-D-S-L family
N8I87_RS37710	COG0477	Major facilitator Superfamily
N8I87_RS37715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N8I87_RS37720	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
N8I87_RS37725	COG0477	Major facilitator Superfamily
N8I87_RS37780	COG2837	iron assimilation
N8I87_RS37790	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
N8I87_RS37805	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N8I87_RS37810	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
N8I87_RS37825	COG0517	IMP dehydrogenase activity
N8I87_RS37825	COG0516	GMP reductase activity
N8I87_RS37855	COG1454	alcohol dehydrogenase
N8I87_RS37855	COG1012	belongs to the aldehyde dehydrogenase family
N8I87_RS37875	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
N8I87_RS37895	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
N8I87_RS37900	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N8I87_RS37900	COG1042	CoA-binding domain protein
N8I87_RS37900	COG0045	succinate-CoA ligase (ADP-forming) activity
N8I87_RS37915	COG0574	Belongs to the PEP-utilizing enzyme family
N8I87_RS37915	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
N8I87_RS37920	COG0516	GMP reductase activity
N8I87_RS37920	COG0517	IMP dehydrogenase activity
N8I87_RS37935	COG2205	protein histidine kinase activity
N8I87_RS37940	COG0745	RESPONSE REGULATOR receiver
N8I87_RS37970	COG2124	cytochrome p450
N8I87_RS37975	COG2124	cytochrome p450
N8I87_RS37980	COG2124	cytochrome p450
N8I87_RS38000	COG0577	efflux transmembrane transporter activity
N8I87_RS38000	COG1136	(ABC) transporter
N8I87_RS38005	COG0577	efflux transmembrane transporter activity
N8I87_RS38005	COG1136	(ABC) transporter
N8I87_RS38015	COG3424	synthase
N8I87_RS38020	COG1024	Enoyl-CoA hydratase
N8I87_RS38025	COG1024	Enoyl-CoA hydratase
N8I87_RS38040	COG1132	(ABC) transporter
N8I87_RS38060	COG3265	gluconokinase activity
N8I87_RS38065	COG1252	NADH dehydrogenase
N8I87_RS38075	COG2133	pyrroloquinoline quinone binding
N8I87_RS38085	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
N8I87_RS38115	COG3979	chitinase
N8I87_RS38125	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
N8I87_RS38150	COG0515	serine threonine protein kinase
N8I87_RS38150	COG2815	serine threonine protein kinase
N8I87_RS38160	COG3290	protein histidine kinase activity
N8I87_RS38165	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
N8I87_RS38180	COG0437	4 iron, 4 sulfur cluster binding
N8I87_RS38190	COG3537	Alpha-1,2-mannosidase
N8I87_RS38195	COG4213	ABC transporter substrate-binding protein
N8I87_RS38205	COG2018	Roadblock/LC7 domain
N8I87_RS38220	COG3629	intracellular signal transduction
N8I87_RS38220	COG3903	Transcriptional regulator
N8I87_RS38250	COG2205	protein histidine kinase activity
N8I87_RS38275	COG0531	amino acid
N8I87_RS38300	COG1472	Belongs to the glycosyl hydrolase 3 family
N8I87_RS38310	COG1309	transcriptional regulator
N8I87_RS38320	COG0463	Glycosyl transferase, family 2
N8I87_RS38350	COG1028	Short-chain dehydrogenase reductase Sdr
N8I87_RS38350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N8I87_RS38350	COG3321	synthase
N8I87_RS38350	COG0318	PFAM AMP-dependent synthetase and ligase
N8I87_RS38350	COG0300	oxidoreductase activity
N8I87_RS38365	COG0583	DNA-binding transcription factor activity
N8I87_RS38370	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
N8I87_RS38385	COG0300	oxidoreductase activity
N8I87_RS38395	COG4716	Myosin-crossreactive antigen
N8I87_RS38400	COG0517	IMP dehydrogenase activity
N8I87_RS38400	COG0516	GMP reductase activity
N8I87_RS38410	COG0517	IMP dehydrogenase activity
N8I87_RS38410	COG0516	GMP reductase activity
N8I87_RS38415	COG0574	Belongs to the PEP-utilizing enzyme family
N8I87_RS38415	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
N8I87_RS38490	COG0709	Synthesizes selenophosphate from selenide and ATP
N8I87_RS38510	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
N8I87_RS38515	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
N8I87_RS38550	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
N8I87_RS38580	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
N8I87_RS38600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N8I87_RS38635	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
N8I87_RS38640	COG3876	Protein conserved in bacteria
N8I87_RS38655	COG1175	transmembrane transport
N8I87_RS38685	COG0142	geranyltranstransferase activity
N8I87_RS38700	COG0326	Molecular chaperone. Has ATPase activity
N8I87_RS38715	COG0604	alcohol dehydrogenase
N8I87_RS38725	COG0604	alcohol dehydrogenase
N8I87_RS38725	COG1028	Short-chain dehydrogenase reductase Sdr
N8I87_RS38725	COG3321	synthase
N8I87_RS38795	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
N8I87_RS38805	COG1088	dTDP-glucose 4,6-dehydratase activity
N8I87_RS38810	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
N8I87_RS38855	COG1215	transferase activity, transferring glycosyl groups
N8I87_RS38955	COG1028	Short-chain dehydrogenase reductase Sdr
N8I87_RS38960	COG1309	transcriptional regulator
N8I87_RS39045	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
N8I87_RS39050	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
N8I87_RS39060	COG0028	Belongs to the TPP enzyme family
N8I87_RS39070	COG2197	response regulator
N8I87_RS39075	COG4585	Histidine kinase
N8I87_RS39095	COG2362	D-Aminopeptidase
N8I87_RS39170	COG2197	response regulator
N8I87_RS39175	COG4585	Histidine kinase
N8I87_RS39195	COG0789	Transcriptional regulator
N8I87_RS39215	COG0438	transferase activity, transferring glycosyl groups
N8I87_RS39225	COG0438	transferase activity, transferring glycosyl groups
N8I87_RS39235	COG2172	sigma factor antagonist activity
N8I87_RS39235	COG1366	Belongs to the anti-sigma-factor antagonist family
N8I87_RS39235	COG2208	phosphoserine phosphatase activity
N8I87_RS39255	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
N8I87_RS39255	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N8I87_RS39260	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
N8I87_RS39265	COG0730	response to heat
N8I87_RS39270	COG1937	Protein conserved in bacteria
N8I87_RS39280	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N8I87_RS39290	COG1252	NADH dehydrogenase
N8I87_RS39295	COG2920	part of a sulfur-relay system
N8I87_RS39315	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
N8I87_RS39320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N8I87_RS39330	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
N8I87_RS39345	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
N8I87_RS39350	COG1280	lysine exporter protein (LysE YggA)
N8I87_RS39355	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
N8I87_RS39370	COG0154	amidase activity
N8I87_RS39410	COG1595	DNA-templated transcription, initiation
N8I87_RS39425	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
N8I87_RS39435	COG3275	phosphorelay sensor kinase activity
N8I87_RS39450	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N8I87_RS39455	COG1584	GPR1 FUN34 yaaH family protein
N8I87_RS39460	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
N8I87_RS39465	COG0563	adenylate kinase activity
N8I87_RS39475	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N8I87_RS39480	COG1278	Cold shock
N8I87_RS39510	COG0247	lactate metabolic process
N8I87_RS39515	COG0277	FAD linked oxidase domain protein
N8I87_RS39520	COG1620	l-lactate permease
N8I87_RS39580	COG1309	transcriptional regulator
N8I87_RS39585	COG1335	isochorismatase
N8I87_RS39590	COG2186	Transcriptional regulator
N8I87_RS39680	COG0302	gtp cyclohydrolase
N8I87_RS39695	COG1595	DNA-templated transcription, initiation
N8I87_RS39730	COG2318	DinB family
N8I87_RS39795	COG3655	Transcriptional regulator
N8I87_RS39840	COG1408	metallophosphoesterase
N8I87_RS39925	COG4585	Histidine kinase
N8I87_RS39930	COG2197	response regulator
N8I87_RS39950	COG3415	Transposase
N8I87_RS39950	COG2801	Transposase and inactivated derivatives
N8I87_RS39960	COG0517	IMP dehydrogenase activity
N8I87_RS39980	COG0204	Acyl-transferase
N8I87_RS40010	COG1012	belongs to the aldehyde dehydrogenase family
N8I87_RS40015	COG1028	Short-chain dehydrogenase reductase Sdr
N8I87_RS40045	COG1309	transcriptional regulator
N8I87_RS40065	COG0477	Major facilitator Superfamily
N8I87_RS40095	COG0583	DNA-binding transcription factor activity
N8I87_RS40120	COG0583	DNA-binding transcription factor activity
N8I87_RS40155	COG1733	regulation of RNA biosynthetic process
N8I87_RS40205	COG1982	Orn Lys Arg decarboxylase major
N8I87_RS40220	COG1295	ribonuclease BN
N8I87_RS40240	COG0517	IMP dehydrogenase activity
N8I87_RS40295	COG1302	Protein conserved in bacteria
N8I87_RS40340	COG2084	Dehydrogenase
N8I87_RS40345	COG1396	sequence-specific DNA binding
N8I87_RS40385	COG2208	phosphoserine phosphatase activity
N8I87_RS40385	COG2770	Histidine kinase
N8I87_RS40395	COG2226	methyltransferase
N8I87_RS40415	COG1278	Cold shock
N8I87_RS40480	COG2205	protein histidine kinase activity
N8I87_RS40500	COG2801	Transposase and inactivated derivatives
N8I87_RS40515	COG1846	Transcriptional regulator
N8I87_RS40515	COG1940	carbohydrate kinase activity
N8I87_RS40535	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
N8I87_RS40555	COG2318	DinB family
N8I87_RS40650	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
N8I87_RS40720	COG3629	intracellular signal transduction
N8I87_RS40720	COG3903	Transcriptional regulator
N8I87_RS40730	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
N8I87_RS40735	COG0596	Alpha beta hydrolase
N8I87_RS40760	COG1309	transcriptional regulator
N8I87_RS40815	COG0745	RESPONSE REGULATOR receiver
N8I87_RS40820	COG5002	protein histidine kinase activity
N8I87_RS40840	COG0800	Aldolase
N8I87_RS40850	COG0395	ABC-type sugar transport system, permease component
N8I87_RS40855	COG1175	transmembrane transport
N8I87_RS40865	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
N8I87_RS40870	COG1012	belongs to the aldehyde dehydrogenase family
N8I87_RS40875	COG1024	Enoyl-CoA hydratase
N8I87_RS40890	COG1609	Transcriptional regulator
N8I87_RS40905	COG0477	Major facilitator Superfamily
N8I87_RS40935	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
N8I87_RS40975	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
N8I87_RS41020	COG1830	Aldolase
N8I87_RS41055	COG0309	Hydrogenase expression formation protein (HypE)
N8I87_RS41080	COG0543	2 iron, 2 sulfur cluster binding
N8I87_RS41135	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
N8I87_RS41140	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
N8I87_RS41190	COG1131	(ABC) transporter
N8I87_RS41205	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
N8I87_RS41295	COG1121	(ABC) transporter
N8I87_RS41310	COG2226	methyltransferase
N8I87_RS41335	COG0604	alcohol dehydrogenase
N8I87_RS41335	COG1028	Short-chain dehydrogenase reductase Sdr
N8I87_RS41335	COG3321	synthase
N8I87_RS41370	COG0483	inositol monophosphate 1-phosphatase activity
N8I87_RS41375	COG0583	DNA-binding transcription factor activity
N8I87_RS41420	COG2130	NADP-dependent
N8I87_RS41425	COG2130	NADP-dependent
N8I87_RS41430	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
N8I87_RS41435	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
N8I87_RS41455	COG4585	Histidine kinase
N8I87_RS41550	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
N8I87_RS41555	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
N8I87_RS41565	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N8I87_RS41575	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
N8I87_RS41630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N8I87_RS41650	COG0318	PFAM AMP-dependent synthetase and ligase
N8I87_RS41655	COG0179	Fumarylacetoacetate (FAA) hydrolase
N8I87_RS41715	COG2826	transposase and inactivated derivatives, IS30 family
N8I87_RS41785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N8I87_RS41825	COG0587	DNA-directed DNA polymerase activity
N8I87_RS41835	COG4249	Peptidase C14 caspase catalytic subunit p20
N8I87_RS41835	COG2319	Wd-40 repeat
N8I87_RS41855	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
N8I87_RS42020	COG1309	transcriptional regulator
N8I87_RS42050	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N8I87_RS42070	COG3547	Transposase (IS116 IS110 IS902 family)
N8I87_RS42100	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
N8I87_RS42125	COG0644	oxidoreductase
N8I87_RS42130	COG0142	geranyltranstransferase activity
N8I87_RS42140	COG1404	Belongs to the peptidase S8 family
N8I87_RS42275	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
N8I87_RS42330	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
N8I87_RS42445	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
N8I87_RS42455	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
N8I87_RS42475	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
N8I87_RS42480	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
N8I87_RS42485	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
N8I87_RS42490	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
N8I87_RS42495	COG1064	alcohol dehydrogenase
N8I87_RS42500	COG0367	asparagine synthase
N8I87_RS42560	COG1309	transcriptional regulator
N8I87_RS42570	COG0702	epimerase
N8I87_RS42595	COG2850	peptidyl-arginine hydroxylation
N8I87_RS42635	COG3903	Transcriptional regulator
N8I87_RS42635	COG2197	response regulator
N8I87_RS42640	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
N8I87_RS42690	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
N8I87_RS42700	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N8I87_RS42860	COG2813	Specifically methylates the guanine in position
N8I87_RS42900	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
N8I87_RS42905	COG0477	Major facilitator Superfamily
N8I87_RS42930	COG1022	Amp-dependent synthetase and ligase
N8I87_RS42945	COG0667	Aldo Keto reductase
N8I87_RS42960	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
N8I87_RS42965	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
N8I87_RS42970	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
N8I87_RS42975	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
N8I87_RS42980	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
N8I87_RS42990	COG1028	Short-chain dehydrogenase reductase Sdr
N8I87_RS42995	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
N8I87_RS43000	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
N8I87_RS43045	COG2267	carboxylic ester hydrolase activity
N8I87_RS43055	COG0318	PFAM AMP-dependent synthetase and ligase
N8I87_RS43075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N8I87_RS43075	COG0604	alcohol dehydrogenase
N8I87_RS43075	COG4221	oxidoreductase activity
N8I87_RS43075	COG3321	synthase
N8I87_RS43085	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
N8I87_RS43185	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
N8I87_RS43190	COG1192	Involved in chromosome partitioning
N8I87_RS43210	COG4044	May play a role in the intracellular transport of hydrophobic ligands
N8I87_RS43245	COG0194	GDP metabolic process
N8I87_RS43250	COG3903	Transcriptional regulator
N8I87_RS43250	COG3629	intracellular signal transduction
N8I87_RS43255	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
N8I87_RS43275	COG0612	Peptidase, M16
N8I87_RS43290	COG4555	ABC transporter
N8I87_RS43370	COG3548	integral membrane protein
N8I87_RS43380	COG2329	Antibiotic biosynthesis monooxygenase
N8I87_RS43540	COG1475	DNA binding
N8I87_RS43560	COG0592	DNA-directed DNA polymerase activity
N8I87_RS43760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N8I87_RS43780	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives