locus-tag	class	description
GWQ54_RS00005	COG3629	intracellular signal transduction
GWQ54_RS00005	COG3903	Transcriptional regulator
GWQ54_RS00020	COG2860	membrane
GWQ54_RS00040	COG0531	amino acid
GWQ54_RS00120	COG0180	Tryptophanyl-tRNA synthetase
GWQ54_RS00145	COG1793	dna ligase
GWQ54_RS00150	COG1289	transmembrane transporter activity
GWQ54_RS00160	COG5640	endopeptidase activity
GWQ54_RS00165	COG0583	DNA-binding transcription factor activity
GWQ54_RS00185	COG2205	protein histidine kinase activity
GWQ54_RS00190	COG0745	RESPONSE REGULATOR receiver
GWQ54_RS00195	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GWQ54_RS00200	COG2197	response regulator
GWQ54_RS00210	COG1222	aaa ATPase
GWQ54_RS00225	COG3629	intracellular signal transduction
GWQ54_RS00225	COG3903	Transcriptional regulator
GWQ54_RS00310	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GWQ54_RS00325	COG1741	Belongs to the pirin family
GWQ54_RS00350	COG1960	acyl-CoA dehydrogenase activity
GWQ54_RS00360	COG1362	aminopeptidase activity
GWQ54_RS00370	COG3903	Transcriptional regulator
GWQ54_RS00370	COG3629	intracellular signal transduction
GWQ54_RS00415	COG0508	dehydrogenase complex catalyzes the overall conversion of
GWQ54_RS00420	COG0022	dehydrogenase e1 component
GWQ54_RS00445	COG0515	serine threonine protein kinase
GWQ54_RS00450	COG0515	serine threonine protein kinase
GWQ54_RS00470	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GWQ54_RS00480	COG0746	molybdenum cofactor guanylyltransferase activity
GWQ54_RS00510	COG1309	transcriptional regulator
GWQ54_RS00515	COG1250	3-hydroxyacyl-CoA dehydrogenase
GWQ54_RS00545	COG3460	Phenylacetate-CoA oxygenase
GWQ54_RS00550	COG3396	Phenylacetate-CoA oxygenase
GWQ54_RS00555	COG2151	metal-sulfur cluster biosynthetic enzyme
GWQ54_RS00560	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GWQ54_RS00585	COG2197	response regulator
GWQ54_RS00590	COG4585	Histidine kinase
GWQ54_RS00600	COG1716	ATPase activity
GWQ54_RS00605	COG1716	ATPase activity
GWQ54_RS00620	COG0768	penicillin binding
GWQ54_RS00625	COG0515	serine threonine protein kinase
GWQ54_RS00630	COG3764	Sortase (surface protein transpeptidase)
GWQ54_RS00635	COG3764	Sortase (surface protein transpeptidase)
GWQ54_RS00650	COG3764	Sortase (surface protein transpeptidase)
GWQ54_RS00665	COG0705	Rhomboid family
GWQ54_RS00690	COG0515	serine threonine protein kinase
GWQ54_RS00720	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GWQ54_RS00730	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
GWQ54_RS00735	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GWQ54_RS00740	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
GWQ54_RS00745	COG0592	DNA-directed DNA polymerase activity
GWQ54_RS00755	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GWQ54_RS00760	COG0594	ribonuclease P activity
GWQ54_RS00765	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GWQ54_RS00770	COG0706	membrane insertase activity
GWQ54_RS00780	COG0357	Ribosomal RNA small subunit methyltransferase G
GWQ54_RS00785	COG1192	Involved in chromosome partitioning
GWQ54_RS00800	COG3118	belongs to the thioredoxin family
GWQ54_RS00805	COG0492	ferredoxin-NADP+ reductase activity
GWQ54_RS00815	COG1595	DNA-templated transcription, initiation
GWQ54_RS00835	COG0617	tRNA 3'-terminal CCA addition
GWQ54_RS00850	COG1260	myo-inositol-1-phosphate synthase
GWQ54_RS00860	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GWQ54_RS00885	COG0360	Binds together with S18 to 16S ribosomal RNA
GWQ54_RS00890	COG0629	single-stranded DNA binding
GWQ54_RS00895	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GWQ54_RS00900	COG0359	binds to the 23S rRNA
GWQ54_RS00910	COG0305	Participates in initiation and elongation during chromosome replication
GWQ54_RS00925	COG0456	acetyltransferase
GWQ54_RS00935	COG2814	Major facilitator Superfamily
GWQ54_RS00970	COG0626	cystathionine gamma-synthase activity
GWQ54_RS00975	COG1950	PFAM Membrane protein of
GWQ54_RS00980	COG0662	Cupin 2, conserved barrel domain protein
GWQ54_RS01005	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GWQ54_RS01055	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GWQ54_RS01060	COG1609	Transcriptional regulator
GWQ54_RS01065	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GWQ54_RS01075	COG1271	oxidase subunit
GWQ54_RS01080	COG1294	oxidase, subunit
GWQ54_RS01085	COG4988	ABC transporter
GWQ54_RS01095	COG0561	phosphatase activity
GWQ54_RS01115	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
GWQ54_RS01130	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GWQ54_RS01135	COG0789	Transcriptional regulator
GWQ54_RS01155	COG1131	(ABC) transporter
GWQ54_RS01165	COG1131	(ABC) transporter
GWQ54_RS01180	COG2807	transmembrane transport
GWQ54_RS01185	COG2186	Transcriptional regulator
GWQ54_RS01195	COG0561	phosphatase activity
GWQ54_RS01200	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GWQ54_RS01205	COG0077	Prephenate dehydratase
GWQ54_RS01210	COG2837	iron assimilation
GWQ54_RS01215	COG2372	response to copper ion
GWQ54_RS01225	COG1999	signal sequence binding
GWQ54_RS01245	COG0006	proline dipeptidase activity
GWQ54_RS01265	COG0653	protein targeting
GWQ54_RS01285	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GWQ54_RS01305	COG1960	acyl-CoA dehydrogenase activity
GWQ54_RS01315	COG1960	acyl-CoA dehydrogenase activity
GWQ54_RS01335	COG1595	DNA-templated transcription, initiation
GWQ54_RS01340	COG0318	PFAM AMP-dependent synthetase and ligase
GWQ54_RS01350	COG0784	Response regulator, receiver
GWQ54_RS01385	COG0745	RESPONSE REGULATOR receiver
GWQ54_RS01390	COG2205	protein histidine kinase activity
GWQ54_RS01400	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GWQ54_RS01405	COG0477	Major facilitator Superfamily
GWQ54_RS01415	COG2353	YceI-like domain
GWQ54_RS01425	COG1846	Transcriptional regulator
GWQ54_RS01440	COG1191	sigma factor activity
GWQ54_RS01445	COG1191	sigma factor activity
GWQ54_RS01475	COG0590	tRNA wobble adenosine to inosine editing
GWQ54_RS01490	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GWQ54_RS01505	COG0433	COG0433 Predicted ATPase
GWQ54_RS01540	COG0745	RESPONSE REGULATOR receiver
GWQ54_RS01565	COG0151	Belongs to the GarS family
GWQ54_RS01580	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GWQ54_RS01590	COG2197	response regulator
GWQ54_RS01625	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GWQ54_RS01630	COG0047	phosphoribosylformylglycinamidine synthase activity
GWQ54_RS01635	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GWQ54_RS01650	COG3119	arylsulfatase activity
GWQ54_RS01660	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GWQ54_RS01695	COG1643	Atp-dependent helicase
GWQ54_RS01705	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GWQ54_RS01705	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GWQ54_RS01710	COG0785	Cytochrome C biogenesis protein
GWQ54_RS01740	COG0513	Belongs to the DEAD box helicase family
GWQ54_RS01820	COG0667	Aldo Keto reductase
GWQ54_RS01830	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GWQ54_RS01835	COG0579	oxidoreductase
GWQ54_RS01865	COG1252	NADH dehydrogenase
GWQ54_RS01880	COG1846	Transcriptional regulator
GWQ54_RS01940	COG0741	lytic transglycosylase activity
GWQ54_RS01940	COG1196	nuclear chromosome segregation
GWQ54_RS01940	COG0739	heme binding
GWQ54_RS01945	COG0671	phosphoesterase, PA-phosphatase related
GWQ54_RS01970	COG1937	Protein conserved in bacteria
GWQ54_RS01980	COG0306	phosphate transporter
GWQ54_RS01985	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GWQ54_RS02005	COG0494	nUDIX hydrolase
GWQ54_RS02005	COG0406	alpha-ribazole phosphatase activity
GWQ54_RS02020	COG0456	acetyltransferase
GWQ54_RS02025	COG0737	Belongs to the 5'-nucleotidase family
GWQ54_RS02035	COG0745	RESPONSE REGULATOR receiver
GWQ54_RS02040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GWQ54_RS02045	COG1609	Transcriptional regulator
GWQ54_RS02050	COG0745	RESPONSE REGULATOR receiver
GWQ54_RS02075	COG2897	thiosulfate sulfurtransferase activity
GWQ54_RS02095	COG3485	protocatechuate 3,4-dioxygenase
GWQ54_RS02110	COG1490	D-aminoacyl-tRNA deacylase activity
GWQ54_RS02125	COG4552	Acetyltransferase involved in intracellular survival and related
GWQ54_RS02130	COG0604	alcohol dehydrogenase
GWQ54_RS02140	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GWQ54_RS02175	COG0438	transferase activity, transferring glycosyl groups
GWQ54_RS02190	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GWQ54_RS02220	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GWQ54_RS02240	COG0588	phosphoglycerate mutase activity
GWQ54_RS02260	COG5002	protein histidine kinase activity
GWQ54_RS02275	COG1329	Transcriptional regulator
GWQ54_RS02280	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GWQ54_RS02285	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GWQ54_RS02290	COG3467	pyridoxamine 5'-phosphate
GWQ54_RS02295	COG0215	cysteine-tRNA ligase activity
GWQ54_RS02300	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GWQ54_RS02310	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GWQ54_RS02320	COG3842	ATPase activity
GWQ54_RS02335	COG0723	plastoquinol--plastocyanin reductase activity
GWQ54_RS02335	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GWQ54_RS02360	COG2197	response regulator
GWQ54_RS02390	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GWQ54_RS02430	COG1105	Belongs to the carbohydrate kinase PfkB family
GWQ54_RS02435	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GWQ54_RS02445	COG1653	transport
GWQ54_RS02455	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GWQ54_RS02455	COG1877	trehalose-phosphatase activity
GWQ54_RS02465	COG0463	Glycosyl transferase, family 2
GWQ54_RS02540	COG1263	PTS System
GWQ54_RS02540	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GWQ54_RS02545	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GWQ54_RS02550	COG1737	Transcriptional regulator
GWQ54_RS02565	COG1278	Cold shock
GWQ54_RS02595	COG3973	AAA domain
GWQ54_RS02600	COG1595	DNA-templated transcription, initiation
GWQ54_RS02615	COG1061	Type III restriction enzyme res subunit
GWQ54_RS02630	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GWQ54_RS02650	COG2268	Band 7 protein
GWQ54_RS02665	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GWQ54_RS02670	COG1120	ATPase activity
GWQ54_RS02675	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GWQ54_RS02680	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GWQ54_RS02695	COG1278	Cold shock
GWQ54_RS02700	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
GWQ54_RS02705	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GWQ54_RS02715	COG2814	Major facilitator Superfamily
GWQ54_RS02730	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GWQ54_RS02740	COG2252	PERMEase
GWQ54_RS02755	COG2814	Major facilitator Superfamily
GWQ54_RS02760	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GWQ54_RS02765	COG0667	Aldo Keto reductase
GWQ54_RS02790	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GWQ54_RS02810	COG1012	belongs to the aldehyde dehydrogenase family
GWQ54_RS02815	COG2318	DinB family
GWQ54_RS02825	COG0076	glutamate decarboxylase activity
GWQ54_RS02830	COG0393	Putative heavy-metal-binding
GWQ54_RS02835	COG0586	Pfam SNARE associated Golgi protein
GWQ54_RS02845	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GWQ54_RS02850	COG2027	D-alanyl-D-alanine carboxypeptidase
GWQ54_RS02860	COG0037	tRNA processing
GWQ54_RS02875	COG0302	gtp cyclohydrolase
GWQ54_RS02890	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GWQ54_RS02915	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GWQ54_RS02915	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GWQ54_RS02930	COG1174	glycine betaine transport
GWQ54_RS02935	COG1174	glycine betaine transport
GWQ54_RS02940	COG1732	Glycine betaine
GWQ54_RS02955	COG0649	NAD binding
GWQ54_RS02970	COG2197	response regulator
GWQ54_RS02975	COG0640	Transcriptional regulator
GWQ54_RS02995	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GWQ54_RS03000	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GWQ54_RS03010	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GWQ54_RS03030	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GWQ54_RS03060	COG0739	heme binding
GWQ54_RS03080	COG2205	protein histidine kinase activity
GWQ54_RS03085	COG0745	RESPONSE REGULATOR receiver
GWQ54_RS03095	COG1595	DNA-templated transcription, initiation
GWQ54_RS03100	COG1194	a g-specific adenine glycosylase
GWQ54_RS03105	COG0671	phosphoesterase, PA-phosphatase related
GWQ54_RS03115	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
GWQ54_RS03135	COG0248	Ppx GppA phosphatase
GWQ54_RS03140	COG1082	Xylose isomerase domain protein TIM barrel
GWQ54_RS03150	COG0129	dihydroxy-acid dehydratase activity
GWQ54_RS03175	COG1129	ABC transporter
GWQ54_RS03175	COG0842	Transport permease protein
GWQ54_RS03185	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GWQ54_RS03210	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GWQ54_RS03220	COG0123	including yeast histone deacetylase and acetoin utilization protein
GWQ54_RS03270	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GWQ54_RS03275	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GWQ54_RS03280	COG0181	hydroxymethylbilane synthase activity
GWQ54_RS03285	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GWQ54_RS03285	COG1648	precorrin-2 dehydrogenase activity
GWQ54_RS03290	COG0113	porphobilinogen synthase activity
GWQ54_RS03335	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GWQ54_RS03345	COG2814	Major facilitator Superfamily
GWQ54_RS03360	COG0018	arginyl-trna synthetase
GWQ54_RS03365	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
GWQ54_RS03385	COG1690	Belongs to the RtcB family
GWQ54_RS03405	COG1742	UPF0060 membrane protein
GWQ54_RS03415	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GWQ54_RS03425	COG1846	Transcriptional regulator
GWQ54_RS03450	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GWQ54_RS03455	COG0640	Transcriptional regulator
GWQ54_RS03470	COG3585	molybdate ion transport
GWQ54_RS03480	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GWQ54_RS03485	COG0406	alpha-ribazole phosphatase activity
GWQ54_RS03495	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GWQ54_RS03500	COG0785	Cytochrome C biogenesis protein
GWQ54_RS03505	COG1333	cytochrome c biogenesis protein
GWQ54_RS03510	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GWQ54_RS03520	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GWQ54_RS03530	COG0163	prenyltransferase activity
GWQ54_RS03540	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
GWQ54_RS03605	COG1278	Cold shock
GWQ54_RS03610	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
GWQ54_RS03625	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GWQ54_RS03630	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
GWQ54_RS03645	COG2226	methyltransferase
GWQ54_RS03675	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GWQ54_RS03680	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GWQ54_RS03685	COG0649	NAD binding
GWQ54_RS03695	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GWQ54_RS03700	COG1034	ATP synthesis coupled electron transport
GWQ54_RS03705	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GWQ54_RS03710	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GWQ54_RS03720	COG0713	ATP synthesis coupled electron transport
GWQ54_RS03725	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GWQ54_RS03735	COG1007	ATP synthesis coupled electron transport
GWQ54_RS03740	COG0514	ATP-dependent DNA helicase (RecQ)
GWQ54_RS03755	COG0492	ferredoxin-NADP+ reductase activity
GWQ54_RS03765	COG3104	oligopeptide transport
GWQ54_RS03770	COG0142	geranyltranstransferase activity
GWQ54_RS03800	COG2234	aminopeptidase activity
GWQ54_RS03800	COG4935	Belongs to the peptidase S8 family
GWQ54_RS03810	COG0488	(ABC) transporter
GWQ54_RS03820	COG0702	epimerase
GWQ54_RS03825	COG1733	regulation of RNA biosynthetic process
GWQ54_RS03830	COG1013	pyruvate-flavodoxin oxidoreductase activity
GWQ54_RS03835	COG0674	pyruvate-flavodoxin oxidoreductase activity
GWQ54_RS03835	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GWQ54_RS03855	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GWQ54_RS03860	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GWQ54_RS03865	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GWQ54_RS03870	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GWQ54_RS03885	COG0713	ATP synthesis coupled electron transport
GWQ54_RS03900	COG1007	ATP synthesis coupled electron transport
GWQ54_RS03905	COG1970	mechanosensitive ion channel activity
GWQ54_RS03910	COG0501	Belongs to the peptidase M48B family
GWQ54_RS03915	COG3304	Inner membrane component domain
GWQ54_RS03920	COG2261	transglycosylase associated protein
GWQ54_RS03930	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GWQ54_RS03935	COG1666	GTP binding
GWQ54_RS03970	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GWQ54_RS03975	COG2030	dehydratase
GWQ54_RS03985	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GWQ54_RS03990	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GWQ54_RS03995	COG0436	Aminotransferase
GWQ54_RS04005	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GWQ54_RS04015	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GWQ54_RS04020	COG0081	regulation of translation
GWQ54_RS04030	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GWQ54_RS04035	COG0222	ribosome binding
GWQ54_RS04040	COG0085	RNA polymerase activity
GWQ54_RS04045	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GWQ54_RS04155	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GWQ54_RS04160	COG0049	tRNA binding
GWQ54_RS04165	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GWQ54_RS04170	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GWQ54_RS04205	COG0051	transcription antitermination factor activity, RNA binding
GWQ54_RS04210	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GWQ54_RS04215	COG0088	Forms part of the polypeptide exit tunnel
GWQ54_RS04220	COG0089	rRNA binding
GWQ54_RS04225	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GWQ54_RS04230	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GWQ54_RS04235	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GWQ54_RS04240	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GWQ54_RS04245	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GWQ54_RS04250	COG0255	Belongs to the universal ribosomal protein uL29 family
GWQ54_RS04255	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GWQ54_RS04260	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GWQ54_RS04265	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GWQ54_RS04270	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GWQ54_RS04275	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GWQ54_RS04280	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GWQ54_RS04285	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GWQ54_RS04290	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GWQ54_RS04295	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GWQ54_RS04305	COG0200	Binds to the 23S rRNA
GWQ54_RS04310	COG0201	protein transport
GWQ54_RS04315	COG0563	adenylate kinase activity
GWQ54_RS04325	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GWQ54_RS04330	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GWQ54_RS04335	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GWQ54_RS04340	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GWQ54_RS04345	COG0202	RNA polymerase activity
GWQ54_RS04350	COG0203	ribosomal protein L17
GWQ54_RS04355	COG0101	tRNA pseudouridine synthase activity
GWQ54_RS04365	COG0488	(ABC) transporter
GWQ54_RS04370	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GWQ54_RS04375	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GWQ54_RS04380	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GWQ54_RS04390	COG1072	(Pantothenic acid kinase))
GWQ54_RS04395	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GWQ54_RS04400	COG0736	holo-[acyl-carrier-protein] synthase activity
GWQ54_RS04415	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GWQ54_RS04425	COG0802	atpase or kinase
GWQ54_RS04450	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GWQ54_RS04460	COG0726	polysaccharide deacetylase
GWQ54_RS04465	COG3973	AAA domain
GWQ54_RS04500	COG0726	polysaccharide deacetylase
GWQ54_RS04505	COG0772	Belongs to the SEDS family
GWQ54_RS04510	COG1316	TRANSCRIPTIONal
GWQ54_RS04515	COG2205	protein histidine kinase activity
GWQ54_RS04520	COG0745	RESPONSE REGULATOR receiver
GWQ54_RS04525	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GWQ54_RS04555	COG1609	Transcriptional regulator
GWQ54_RS04565	COG4221	oxidoreductase activity
GWQ54_RS04575	COG0583	DNA-binding transcription factor activity
GWQ54_RS04590	COG1595	DNA-templated transcription, initiation
GWQ54_RS04600	COG0516	GMP reductase activity
GWQ54_RS04615	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GWQ54_RS04635	COG0515	serine threonine protein kinase
GWQ54_RS04640	COG0515	serine threonine protein kinase
GWQ54_RS04640	COG2815	serine threonine protein kinase
GWQ54_RS04645	COG1012	belongs to the aldehyde dehydrogenase family
GWQ54_RS04665	COG0519	Catalyzes the synthesis of GMP from XMP
GWQ54_RS04665	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GWQ54_RS04695	COG2197	response regulator
GWQ54_RS04730	COG0739	heme binding
GWQ54_RS04740	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GWQ54_RS04755	COG0714	Associated with various cellular activities
GWQ54_RS04760	COG2425	protein containing a von Willebrand factor type A (vWA) domain
GWQ54_RS04765	COG3552	Protein containing von Willebrand factor type A (VWA) domain
GWQ54_RS04770	COG0045	succinate-CoA ligase (ADP-forming) activity
GWQ54_RS04800	COG0138	bifunctional purine biosynthesis protein purh
GWQ54_RS04810	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GWQ54_RS04820	COG4585	Histidine kinase
GWQ54_RS04825	COG2197	response regulator
GWQ54_RS04835	COG0039	L-malate dehydrogenase activity
GWQ54_RS04850	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GWQ54_RS04855	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GWQ54_RS04860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GWQ54_RS04880	COG0754	glutathionylspermidine amidase activity
GWQ54_RS04900	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GWQ54_RS04905	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GWQ54_RS04910	COG0180	Tryptophanyl-tRNA synthetase
GWQ54_RS04925	COG0277	FAD linked oxidase domain protein
GWQ54_RS04930	COG0671	phosphoesterase, PA-phosphatase related
GWQ54_RS04950	COG1686	Belongs to the peptidase S11 family
GWQ54_RS04960	COG0747	negative chemotaxis
GWQ54_RS04980	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GWQ54_RS04985	COG1053	succinate dehydrogenase
GWQ54_RS04995	COG2009	succinate dehydrogenase
GWQ54_RS05005	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GWQ54_RS05010	COG1595	DNA-templated transcription, initiation
GWQ54_RS05025	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GWQ54_RS05025	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GWQ54_RS05035	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GWQ54_RS05055	COG1216	Glycosyl transferase, family 2
GWQ54_RS05070	COG2089	acid synthase
GWQ54_RS05080	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
GWQ54_RS05080	COG1473	amidohydrolase
GWQ54_RS05085	COG1744	ABC transporter substrate-binding protein PnrA-like
GWQ54_RS05090	COG3845	ABC transporter
GWQ54_RS05095	COG4603	Belongs to the binding-protein-dependent transport system permease family
GWQ54_RS05100	COG1079	Belongs to the binding-protein-dependent transport system permease family
GWQ54_RS05130	COG2814	Major facilitator Superfamily
GWQ54_RS05135	COG0583	DNA-binding transcription factor activity
GWQ54_RS05145	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GWQ54_RS05175	COG2205	protein histidine kinase activity
GWQ54_RS05180	COG0745	RESPONSE REGULATOR receiver
GWQ54_RS05185	COG1595	DNA-templated transcription, initiation
GWQ54_RS05200	COG1012	belongs to the aldehyde dehydrogenase family
GWQ54_RS05205	COG1012	belongs to the aldehyde dehydrogenase family
GWQ54_RS05235	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GWQ54_RS05275	COG1476	TRANSCRIPTIONal
GWQ54_RS05290	COG4770	biotin carboxylase activity
GWQ54_RS05300	COG0424	maF-like protein
GWQ54_RS05315	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GWQ54_RS05330	COG1024	Enoyl-CoA hydratase
GWQ54_RS05340	COG2986	histidine ammonia-lyase
GWQ54_RS05365	COG1064	alcohol dehydrogenase
GWQ54_RS05375	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GWQ54_RS05395	COG1595	DNA-templated transcription, initiation
GWQ54_RS05405	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GWQ54_RS05420	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GWQ54_RS05430	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GWQ54_RS05440	COG2255	four-way junction helicase activity
GWQ54_RS05450	COG1331	Highly conserved protein containing a thioredoxin domain
GWQ54_RS05460	COG1309	transcriptional regulator
GWQ54_RS05470	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
GWQ54_RS05500	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
GWQ54_RS05515	COG1414	Transcriptional regulator
GWQ54_RS05520	COG0251	oxidation-reduction process
GWQ54_RS05525	COG2610	gluconate transmembrane transporter activity
GWQ54_RS05550	COG2894	cell division
GWQ54_RS05585	COG2197	response regulator
GWQ54_RS05605	COG2885	chlorophyll binding
GWQ54_RS05620	COG2226	methyltransferase
GWQ54_RS05630	COG0667	Aldo Keto reductase
GWQ54_RS05635	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GWQ54_RS05640	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GWQ54_RS05655	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GWQ54_RS05660	COG0450	alkyl hydroperoxide reductase
GWQ54_RS05675	COG1136	(ABC) transporter
GWQ54_RS05690	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GWQ54_RS05705	COG0114	fumarate hydratase activity
GWQ54_RS05720	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GWQ54_RS05720	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GWQ54_RS05745	COG0778	Nitroreductase
GWQ54_RS05750	COG1722	exodeoxyribonuclease VII activity
GWQ54_RS05755	COG1570	exodeoxyribonuclease VII activity
GWQ54_RS05765	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GWQ54_RS05780	COG0012	GTP binding
GWQ54_RS05795	COG0475	glutathione-regulated potassium exporter activity
GWQ54_RS05865	COG1053	succinate dehydrogenase
GWQ54_RS05885	COG1217	gtp-binding protein TYPA
GWQ54_RS05900	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GWQ54_RS05905	COG0444	Belongs to the ABC transporter superfamily
GWQ54_RS05910	COG4608	Belongs to the ABC transporter superfamily
GWQ54_RS05920	COG0601	transmembrane transport
GWQ54_RS05925	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GWQ54_RS05935	COG4608	Belongs to the ABC transporter superfamily
GWQ54_RS05945	COG4608	Belongs to the ABC transporter superfamily
GWQ54_RS05950	COG0444	Belongs to the ABC transporter superfamily
GWQ54_RS05955	COG0601	transmembrane transport
GWQ54_RS05960	COG0747	negative chemotaxis
GWQ54_RS05965	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GWQ54_RS05980	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GWQ54_RS05995	COG1131	(ABC) transporter
GWQ54_RS06005	COG4585	Histidine kinase
GWQ54_RS06010	COG2197	response regulator
GWQ54_RS06050	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GWQ54_RS06055	COG1611	Belongs to the LOG family
GWQ54_RS06060	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GWQ54_RS06070	COG2818	Glycosylase
GWQ54_RS06075	COG1024	Enoyl-CoA hydratase
GWQ54_RS06090	COG1595	DNA-templated transcription, initiation
GWQ54_RS06100	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GWQ54_RS06105	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GWQ54_RS06155	COG0598	Magnesium transport protein CorA
GWQ54_RS06165	COG2814	Major facilitator Superfamily
GWQ54_RS06180	COG2095	MarC family integral membrane protein
GWQ54_RS06190	COG1432	Conserved Protein
GWQ54_RS06195	COG0596	Alpha beta hydrolase
GWQ54_RS06230	COG2267	carboxylic ester hydrolase activity
GWQ54_RS06240	COG0747	negative chemotaxis
GWQ54_RS06245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GWQ54_RS06250	COG0601	transmembrane transport
GWQ54_RS06290	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
GWQ54_RS06295	COG0535	radical SAM domain protein
GWQ54_RS06310	COG1140	nitrate reductase beta subunit
GWQ54_RS06340	COG0210	DNA helicase
GWQ54_RS06385	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GWQ54_RS06440	COG3480	Lon protease (S16) C-terminal proteolytic domain
GWQ54_RS06450	COG1615	UPF0182 protein
GWQ54_RS06475	COG0753	catalase activity
GWQ54_RS06485	COG0483	inositol monophosphate 1-phosphatase activity
GWQ54_RS06495	COG2076	Multidrug Resistance protein
GWQ54_RS06505	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GWQ54_RS06515	COG2135	peptidase activity
GWQ54_RS06525	COG1595	DNA-templated transcription, initiation
GWQ54_RS06530	COG5662	AntiSigma factor
GWQ54_RS06535	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GWQ54_RS06535	COG2199	diguanylate cyclase activity
GWQ54_RS06550	COG0242	peptide deformylase activity
GWQ54_RS06555	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GWQ54_RS06585	COG0667	Aldo Keto reductase
GWQ54_RS06600	COG1215	transferase activity, transferring glycosyl groups
GWQ54_RS06605	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GWQ54_RS06610	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GWQ54_RS06625	COG1215	transferase activity, transferring glycosyl groups
GWQ54_RS06640	COG2188	Transcriptional regulator
GWQ54_RS06645	COG2182	Extracellular solute-binding protein
GWQ54_RS06650	COG1175	transmembrane transport
GWQ54_RS06655	COG0395	ABC-type sugar transport system, permease component
GWQ54_RS06660	COG1472	Belongs to the glycosyl hydrolase 3 family
GWQ54_RS06675	COG0019	diaminopimelate decarboxylase activity
GWQ54_RS06680	COG0738	Major facilitator superfamily
GWQ54_RS06685	COG0363	glucosamine-6-phosphate deaminase activity
GWQ54_RS06700	COG1597	lipid kinase activity
GWQ54_RS06715	COG2172	sigma factor antagonist activity
GWQ54_RS06730	COG2515	1-aminocyclopropane-1-carboxylate deaminase
GWQ54_RS06740	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GWQ54_RS06740	COG1017	nitric oxide dioxygenase activity
GWQ54_RS06745	COG1959	2 iron, 2 sulfur cluster binding
GWQ54_RS06750	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GWQ54_RS06755	COG0142	geranyltranstransferase activity
GWQ54_RS06775	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GWQ54_RS06785	COG3896	Chloramphenicol phosphotransferase-like protein
GWQ54_RS06810	COG4106	trans-aconitate 2-methyltransferase activity
GWQ54_RS06815	COG1126	abc transporter atp-binding protein
GWQ54_RS06820	COG0765	amino acid transport
GWQ54_RS06835	COG0604	alcohol dehydrogenase
GWQ54_RS06875	COG0567	Dehydrogenase, E1 component
GWQ54_RS06875	COG0508	dehydrogenase complex catalyzes the overall conversion of
GWQ54_RS06880	COG2205	protein histidine kinase activity
GWQ54_RS06885	COG0745	RESPONSE REGULATOR receiver
GWQ54_RS06910	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GWQ54_RS06960	COG0791	NLP P60 protein
GWQ54_RS06960	COG3883	PFAM NLP P60 protein
GWQ54_RS06995	COG0768	penicillin binding
GWQ54_RS07010	COG2205	protein histidine kinase activity
GWQ54_RS07035	COG3795	YCII-related domain
GWQ54_RS07040	COG4941	Belongs to the sigma-70 factor family
GWQ54_RS07050	COG1793	dna ligase
GWQ54_RS07050	COG3285	dna ligase
GWQ54_RS07055	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
GWQ54_RS07060	COG2770	Histidine kinase
GWQ54_RS07060	COG2208	phosphoserine phosphatase activity
GWQ54_RS07070	COG1674	ftsk spoiiie
GWQ54_RS07115	COG0789	Transcriptional regulator
GWQ54_RS07150	COG0018	arginyl-trna synthetase
GWQ54_RS07155	COG0019	diaminopimelate decarboxylase activity
GWQ54_RS07160	COG0460	homoserine dehydrogenase
GWQ54_RS07165	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GWQ54_RS07170	COG0083	homoserine kinase activity
GWQ54_RS07180	COG1316	TRANSCRIPTIONal
GWQ54_RS07185	COG0254	rRNA binding
GWQ54_RS07190	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GWQ54_RS07195	COG2890	protein-(glutamine-N5) methyltransferase activity
GWQ54_RS07205	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GWQ54_RS07210	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GWQ54_RS07230	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GWQ54_RS07235	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GWQ54_RS07240	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GWQ54_RS07245	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GWQ54_RS07250	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GWQ54_RS07255	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GWQ54_RS07260	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GWQ54_RS07275	COG2197	response regulator
GWQ54_RS07280	COG4585	Histidine kinase
GWQ54_RS07290	COG0745	RESPONSE REGULATOR receiver
GWQ54_RS07295	COG2205	protein histidine kinase activity
GWQ54_RS07330	COG1250	3-hydroxyacyl-CoA dehydrogenase
GWQ54_RS07345	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
GWQ54_RS07400	COG0183	Belongs to the thiolase family
GWQ54_RS07465	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GWQ54_RS07465	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GWQ54_RS07470	COG2205	protein histidine kinase activity
GWQ54_RS07480	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GWQ54_RS07530	COG1686	Belongs to the peptidase S11 family
GWQ54_RS07540	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GWQ54_RS07545	COG0280	phosphate acetyltransferase
GWQ54_RS07545	COG0857	belongs to the CobB CobQ family
GWQ54_RS07550	COG0205	6-phosphofructokinase activity
GWQ54_RS07560	COG3833	ABC-type maltose transport systems, permease component
GWQ54_RS07570	COG1653	transport
GWQ54_RS07575	COG4565	transcriptional regulatory protein
GWQ54_RS07580	COG3290	protein histidine kinase activity
GWQ54_RS07585	COG1301	dicarboxylic acid transport
GWQ54_RS07605	COG0477	Major facilitator Superfamily
GWQ54_RS07610	COG0789	Transcriptional regulator
GWQ54_RS07630	COG1653	transport
GWQ54_RS07635	COG1175	transmembrane transport
GWQ54_RS07640	COG0395	ABC-type sugar transport system, permease component
GWQ54_RS07655	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GWQ54_RS07660	COG3281	Trehalose synthase
GWQ54_RS07665	COG0366	Alpha amylase catalytic
GWQ54_RS07670	COG0366	Alpha amylase catalytic
GWQ54_RS07675	COG0058	SHG alpha-glucan phosphorylase activity
GWQ54_RS07690	COG2318	DinB family
GWQ54_RS07700	COG1132	(ABC) transporter
GWQ54_RS07705	COG1132	(ABC) transporter
GWQ54_RS07710	COG1131	(ABC) transporter
GWQ54_RS07720	COG4585	Histidine kinase
GWQ54_RS07725	COG2197	response regulator
GWQ54_RS07735	COG1376	ErfK ybiS ycfS ynhG family protein
GWQ54_RS07755	COG0726	polysaccharide deacetylase
GWQ54_RS07780	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GWQ54_RS07785	COG1760	l-serine dehydratase
GWQ54_RS07790	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GWQ54_RS07795	COG0509	glycine decarboxylation via glycine cleavage system
GWQ54_RS07800	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GWQ54_RS07820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GWQ54_RS07825	COG4166	transmembrane transport
GWQ54_RS07835	COG0444	Belongs to the ABC transporter superfamily
GWQ54_RS07840	COG4608	Belongs to the ABC transporter superfamily
GWQ54_RS07850	COG2860	membrane
GWQ54_RS07885	COG0482	sulfurtransferase activity
GWQ54_RS07910	COG4221	oxidoreductase activity
GWQ54_RS07920	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GWQ54_RS07940	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GWQ54_RS07945	COG0154	amidase activity
GWQ54_RS07955	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GWQ54_RS07980	COG0577	efflux transmembrane transporter activity
GWQ54_RS07980	COG1136	(ABC) transporter
GWQ54_RS07985	COG1136	(ABC) transporter
GWQ54_RS07985	COG0577	efflux transmembrane transporter activity
GWQ54_RS07990	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GWQ54_RS08005	COG2197	response regulator
GWQ54_RS08010	COG2133	pyrroloquinoline quinone binding
GWQ54_RS08015	COG0656	L-ascorbic acid biosynthetic process
GWQ54_RS08025	COG5001	Diguanylate cyclase
GWQ54_RS08025	COG3300	MHYT domain
GWQ54_RS08035	COG0440	acetolactate synthase activity
GWQ54_RS08040	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GWQ54_RS08045	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GWQ54_RS08060	COG0506	proline dehydrogenase activity
GWQ54_RS08065	COG1012	belongs to the aldehyde dehydrogenase family
GWQ54_RS08070	COG0778	Nitroreductase
GWQ54_RS08070	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
GWQ54_RS08085	COG3511	phospholipase C
GWQ54_RS08095	COG1695	Transcriptional regulator
GWQ54_RS08105	COG0477	Major facilitator Superfamily
GWQ54_RS08115	COG0473	3-isopropylmalate dehydrogenase activity
GWQ54_RS08120	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GWQ54_RS08130	COG0832	Belongs to the urease beta subunit family
GWQ54_RS08130	COG0831	urea catabolic process
GWQ54_RS08135	COG0804	urea catabolic process
GWQ54_RS08140	COG2957	Belongs to the agmatine deiminase family
GWQ54_RS08150	COG0477	Major facilitator Superfamily
GWQ54_RS08155	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GWQ54_RS08170	COG1028	Short-chain dehydrogenase reductase Sdr
GWQ54_RS08180	COG2353	YceI-like domain
GWQ54_RS08195	COG1349	DNA-binding transcription factor activity
GWQ54_RS08205	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GWQ54_RS08220	COG0596	Alpha beta hydrolase
GWQ54_RS08235	COG2018	Roadblock/LC7 domain
GWQ54_RS08255	COG2018	Roadblock/LC7 domain
GWQ54_RS08260	COG5002	protein histidine kinase activity
GWQ54_RS08270	COG0179	Fumarylacetoacetate (FAA) hydrolase
GWQ54_RS08275	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GWQ54_RS08285	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
GWQ54_RS08315	COG0789	Transcriptional regulator
GWQ54_RS08325	COG1414	Transcriptional regulator
GWQ54_RS08330	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GWQ54_RS08335	COG0066	3-isopropylmalate dehydratase activity
GWQ54_RS08345	COG0776	regulation of translation
GWQ54_RS08355	COG1920	GTP binding
GWQ54_RS08365	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GWQ54_RS08370	COG1181	Belongs to the D-alanine--D-alanine ligase family
GWQ54_RS08390	COG0351	phosphomethylpyrimidine kinase
GWQ54_RS08395	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GWQ54_RS08400	COG1461	Dihydroxyacetone kinase
GWQ54_RS08410	COG0742	ribosomal rna small subunit methyltransferase
GWQ54_RS08415	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GWQ54_RS08430	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GWQ54_RS08435	COG0571	ribonuclease III activity
GWQ54_RS08440	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GWQ54_RS08445	COG1733	regulation of RNA biosynthetic process
GWQ54_RS08455	COG2340	Cysteine-rich secretory protein family
GWQ54_RS08460	COG1254	Belongs to the acylphosphatase family
GWQ54_RS08470	COG1196	nuclear chromosome segregation
GWQ54_RS08475	COG0477	Major facilitator Superfamily
GWQ54_RS08480	COG1950	PFAM Membrane protein of
GWQ54_RS08520	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GWQ54_RS08530	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GWQ54_RS08540	COG0442	prolyl-tRNA aminoacylation
GWQ54_RS08550	COG0228	four-way junction DNA binding
GWQ54_RS08555	COG1837	Belongs to the UPF0109 family
GWQ54_RS08560	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GWQ54_RS08565	COG0336	Belongs to the RNA methyltransferase TrmD family
GWQ54_RS08570	COG0335	large ribosomal subunit rRNA binding
GWQ54_RS08575	COG0681	Belongs to the peptidase S26 family
GWQ54_RS08580	COG0681	Belongs to the peptidase S26 family
GWQ54_RS08585	COG0681	Belongs to the peptidase S26 family
GWQ54_RS08605	COG0792	nuclease activity
GWQ54_RS08620	COG1191	sigma factor activity
GWQ54_RS08635	COG0052	Belongs to the universal ribosomal protein uS2 family
GWQ54_RS08640	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GWQ54_RS08645	COG0528	UMP kinase activity
GWQ54_RS08650	COG0233	cytoplasmic translational termination
GWQ54_RS08655	COG0575	Belongs to the CDS family
GWQ54_RS08660	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GWQ54_RS08670	COG1177	transmembrane transport
GWQ54_RS08675	COG3842	ATPase activity
GWQ54_RS08695	COG1136	(ABC) transporter
GWQ54_RS08700	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GWQ54_RS08710	COG1012	belongs to the aldehyde dehydrogenase family
GWQ54_RS08730	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GWQ54_RS08755	COG3842	ATPase activity
GWQ54_RS08760	COG1176	ABC-type spermidine putrescine transport system, permease component I
GWQ54_RS08765	COG1177	transmembrane transport
GWQ54_RS08770	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GWQ54_RS08800	COG2508	Transcriptional regulator
GWQ54_RS08815	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GWQ54_RS08820	COG0750	zinc metalloprotease
GWQ54_RS08825	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GWQ54_RS08840	COG0442	prolyl-tRNA aminoacylation
GWQ54_RS08860	COG0779	Required for maturation of 30S ribosomal subunits
GWQ54_RS08875	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GWQ54_RS08885	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GWQ54_RS08890	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GWQ54_RS08905	COG4608	Belongs to the ABC transporter superfamily
GWQ54_RS08910	COG0444	Belongs to the ABC transporter superfamily
GWQ54_RS08920	COG0601	transmembrane transport
GWQ54_RS08925	COG4166	transmembrane transport
GWQ54_RS08930	COG0455	bacterial-type flagellum organization
GWQ54_RS08950	COG1404	Belongs to the peptidase S8 family
GWQ54_RS08965	COG1404	Belongs to the peptidase S8 family
GWQ54_RS08985	COG1674	ftsk spoiiie
GWQ54_RS08995	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GWQ54_RS09000	COG1185	polyribonucleotide nucleotidyltransferase activity
GWQ54_RS09005	COG0612	Peptidase, M16
GWQ54_RS09010	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GWQ54_RS09030	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
GWQ54_RS09035	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GWQ54_RS09040	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GWQ54_RS09070	COG2208	phosphoserine phosphatase activity
GWQ54_RS09070	COG2770	Histidine kinase
GWQ54_RS09075	COG2205	protein histidine kinase activity
GWQ54_RS09075	COG4999	Histidine kinase
GWQ54_RS09075	COG3850	Histidine kinase
GWQ54_RS09075	COG3437	response regulator, receiver
GWQ54_RS09085	COG1674	ftsk spoiiie
GWQ54_RS09095	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GWQ54_RS09105	COG1546	Belongs to the CinA family
GWQ54_RS09105	COG1058	Belongs to the CinA family
GWQ54_RS09110	COG1396	sequence-specific DNA binding
GWQ54_RS09115	COG0783	Belongs to the Dps family
GWQ54_RS09125	COG1028	Short-chain dehydrogenase reductase Sdr
GWQ54_RS09130	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GWQ54_RS09135	COG1201	RNA secondary structure unwinding
GWQ54_RS09140	COG2207	Transcriptional regulator
GWQ54_RS09140	COG1917	Cupin 2, conserved barrel domain protein
GWQ54_RS09170	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GWQ54_RS09180	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GWQ54_RS09195	COG0765	amino acid transport
GWQ54_RS09200	COG0765	amino acid transport
GWQ54_RS09205	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GWQ54_RS09210	COG1126	abc transporter atp-binding protein
GWQ54_RS09215	COG0745	RESPONSE REGULATOR receiver
GWQ54_RS09220	COG2205	protein histidine kinase activity
GWQ54_RS09225	COG2358	TRAP transporter, solute receptor (TAXI family
GWQ54_RS09230	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GWQ54_RS09245	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GWQ54_RS09255	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GWQ54_RS09260	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GWQ54_RS09270	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GWQ54_RS09310	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GWQ54_RS09315	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GWQ54_RS09320	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GWQ54_RS09335	COG0588	phosphoglycerate mutase activity
GWQ54_RS09345	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GWQ54_RS09380	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GWQ54_RS09390	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GWQ54_RS09405	COG0187	DNA topoisomerase II activity
GWQ54_RS09415	COG4585	Histidine kinase
GWQ54_RS09420	COG2197	response regulator
GWQ54_RS09430	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GWQ54_RS09435	COG4565	transcriptional regulatory protein
GWQ54_RS09445	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GWQ54_RS09460	COG3290	protein histidine kinase activity
GWQ54_RS09480	COG1175	transmembrane transport
GWQ54_RS09490	COG0366	Alpha amylase catalytic
GWQ54_RS09500	COG2267	carboxylic ester hydrolase activity
GWQ54_RS09505	COG0372	Belongs to the citrate synthase family
GWQ54_RS09510	COG0372	Belongs to the citrate synthase family
GWQ54_RS09520	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GWQ54_RS09525	COG0612	Peptidase, M16
GWQ54_RS09535	COG0739	heme binding
GWQ54_RS09540	COG1802	Transcriptional regulator
GWQ54_RS09545	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GWQ54_RS09565	COG1435	thymidine kinase activity
GWQ54_RS09630	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GWQ54_RS09645	COG0745	RESPONSE REGULATOR receiver
GWQ54_RS09650	COG2205	protein histidine kinase activity
GWQ54_RS09675	COG0756	dUTP diphosphatase activity
GWQ54_RS09685	COG1136	(ABC) transporter
GWQ54_RS09685	COG4591	ABC-type transport system involved in lipoprotein release permease component
GWQ54_RS09715	COG0569	domain protein
GWQ54_RS09720	COG0531	amino acid
GWQ54_RS09725	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GWQ54_RS09750	COG2815	serine threonine protein kinase
GWQ54_RS09750	COG0515	serine threonine protein kinase
GWQ54_RS09760	COG0210	DNA helicase
GWQ54_RS09770	COG1401	restriction endodeoxyribonuclease activity
GWQ54_RS09800	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GWQ54_RS09810	COG2815	serine threonine protein kinase
GWQ54_RS09810	COG0515	serine threonine protein kinase
GWQ54_RS09825	COG3209	COG3209 Rhs family protein
GWQ54_RS09835	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
GWQ54_RS09845	COG1799	cell septum assembly
GWQ54_RS09875	COG2040	homocysteine
GWQ54_RS09885	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GWQ54_RS09895	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GWQ54_RS09900	COG0531	amino acid
GWQ54_RS09910	COG1024	Enoyl-CoA hydratase
GWQ54_RS09930	COG1960	acyl-CoA dehydrogenase activity
GWQ54_RS09940	COG0006	proline dipeptidase activity
GWQ54_RS09950	COG3938	Belongs to the proline racemase family
GWQ54_RS09960	COG3486	L-lysine 6-monooxygenase (NADPH) activity
GWQ54_RS09965	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GWQ54_RS09970	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GWQ54_RS09975	COG1120	ATPase activity
GWQ54_RS09985	COG1132	(ABC) transporter
GWQ54_RS09995	COG1132	(ABC) transporter
GWQ54_RS10000	COG2382	esterase
GWQ54_RS10010	COG1228	amidohydrolase
GWQ54_RS10020	COG0456	acetyltransferase
GWQ54_RS10025	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GWQ54_RS10030	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GWQ54_RS10035	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GWQ54_RS10040	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GWQ54_RS10050	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GWQ54_RS10060	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GWQ54_RS10080	COG1653	transport
GWQ54_RS10085	COG1175	transmembrane transport
GWQ54_RS10090	COG0395	ABC-type sugar transport system, permease component
GWQ54_RS10095	COG1940	carbohydrate kinase activity
GWQ54_RS10100	COG4213	ABC transporter substrate-binding protein
GWQ54_RS10110	COG4214	carbohydrate transport
GWQ54_RS10115	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GWQ54_RS10120	COG0531	amino acid
GWQ54_RS10135	COG1024	Enoyl-CoA hydratase
GWQ54_RS10135	COG1250	3-hydroxyacyl-CoA dehydrogenase
GWQ54_RS10140	COG0183	Belongs to the thiolase family
GWQ54_RS10145	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
GWQ54_RS10160	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GWQ54_RS10165	COG0446	pyridine nucleotide-disulphide oxidoreductase
GWQ54_RS10170	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
GWQ54_RS10175	COG3253	May function as heme-dependent peroxidase
GWQ54_RS10195	COG3220	belongs to the UPF0276 family
GWQ54_RS10230	COG2326	polyphosphate kinase activity
GWQ54_RS10255	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GWQ54_RS10260	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GWQ54_RS10265	COG3903	Transcriptional regulator
GWQ54_RS10265	COG3629	intracellular signal transduction
GWQ54_RS10275	COG3629	intracellular signal transduction
GWQ54_RS10275	COG3903	Transcriptional regulator
GWQ54_RS10300	COG0577	efflux transmembrane transporter activity
GWQ54_RS10300	COG1136	(ABC) transporter
GWQ54_RS10350	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GWQ54_RS10355	COG2091	lysine biosynthetic process via aminoadipic acid
GWQ54_RS10360	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GWQ54_RS10400	COG0346	lactoylglutathione lyase activity
GWQ54_RS10435	COG2124	cytochrome p450
GWQ54_RS10495	COG0667	Aldo Keto reductase
GWQ54_RS10500	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GWQ54_RS10515	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GWQ54_RS10520	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
GWQ54_RS10540	COG0529	Catalyzes the synthesis of activated sulfate
GWQ54_RS10545	COG0175	sulfate reduction
GWQ54_RS10555	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GWQ54_RS10565	COG3284	Transcriptional regulator
GWQ54_RS10570	COG1960	acyl-CoA dehydrogenase activity
GWQ54_RS10590	COG0640	Transcriptional regulator
GWQ54_RS10595	COG1116	anion transmembrane transporter activity
GWQ54_RS10605	COG1162	GTPase activity
GWQ54_RS10615	COG0387	Pfam Sodium calcium exchanger
GWQ54_RS10620	COG0367	asparagine synthase
GWQ54_RS10640	COG1404	Belongs to the peptidase S8 family
GWQ54_RS10650	COG0028	Belongs to the TPP enzyme family
GWQ54_RS10675	COG1802	Transcriptional regulator
GWQ54_RS10685	COG3835	regulator
GWQ54_RS10700	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GWQ54_RS10705	COG2252	PERMEase
GWQ54_RS10715	COG4552	Acetyltransferase involved in intracellular survival and related
GWQ54_RS10725	COG2272	Belongs to the type-B carboxylesterase lipase family
GWQ54_RS10735	COG2197	response regulator
GWQ54_RS10745	COG1278	Cold shock
GWQ54_RS10750	COG0513	Belongs to the DEAD box helicase family
GWQ54_RS10760	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
GWQ54_RS10765	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
GWQ54_RS10770	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
GWQ54_RS10780	COG2124	cytochrome p450
GWQ54_RS10840	COG0318	PFAM AMP-dependent synthetase and ligase
GWQ54_RS10850	COG3960	tartronate-semialdehyde synthase activity
GWQ54_RS10855	COG0640	Transcriptional regulator
GWQ54_RS10885	COG0753	catalase activity
GWQ54_RS10890	COG2084	Dehydrogenase
GWQ54_RS10895	COG3622	Belongs to the hyi family
GWQ54_RS10915	COG2351	hydroxyisourate hydrolase activity
GWQ54_RS10925	COG2233	PERMEase
GWQ54_RS10935	COG2233	PERMEase
GWQ54_RS10940	COG1263	PTS System
GWQ54_RS10950	COG1349	DNA-binding transcription factor activity
GWQ54_RS10965	COG1357	PFAM Pentapeptide repeats (8 copies)
GWQ54_RS10980	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GWQ54_RS10985	COG1288	antiporter activity
GWQ54_RS10990	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GWQ54_RS11005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GWQ54_RS11030	COG2197	response regulator
GWQ54_RS11035	COG4585	Histidine kinase
GWQ54_RS11040	COG0577	efflux transmembrane transporter activity
GWQ54_RS11050	COG1414	Transcriptional regulator
GWQ54_RS11055	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GWQ54_RS11060	COG4266	Belongs to the allantoicase family
GWQ54_RS11080	COG2197	response regulator
GWQ54_RS11095	COG0673	inositol 2-dehydrogenase activity
GWQ54_RS11100	COG2188	Transcriptional regulator
GWQ54_RS11125	COG1940	carbohydrate kinase activity
GWQ54_RS11135	COG0596	Alpha beta hydrolase
GWQ54_RS11155	COG1126	abc transporter atp-binding protein
GWQ54_RS11160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GWQ54_RS11165	COG0765	amino acid transport
GWQ54_RS11170	COG0765	amino acid transport
GWQ54_RS11180	COG1376	ErfK ybiS ycfS ynhG family protein
GWQ54_RS11195	COG0745	RESPONSE REGULATOR receiver
GWQ54_RS11200	COG2205	protein histidine kinase activity
GWQ54_RS11230	COG0405	Gamma-glutamyltransferase
GWQ54_RS11265	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GWQ54_RS11270	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GWQ54_RS11290	COG0483	inositol monophosphate 1-phosphatase activity
GWQ54_RS11310	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GWQ54_RS11320	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GWQ54_RS11330	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GWQ54_RS11335	COG1929	Belongs to the glycerate kinase type-1 family
GWQ54_RS11350	COG0688	phosphatidylethanolamine metabolic process
GWQ54_RS11355	COG1960	acyl-CoA dehydrogenase activity
GWQ54_RS11365	COG2301	Belongs to the HpcH HpaI aldolase family
GWQ54_RS11370	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GWQ54_RS11370	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GWQ54_RS11375	COG0604	alcohol dehydrogenase
GWQ54_RS11385	COG1250	3-hydroxyacyl-CoA dehydrogenase
GWQ54_RS11420	COG1366	Belongs to the anti-sigma-factor antagonist family
GWQ54_RS11420	COG2172	sigma factor antagonist activity
GWQ54_RS11420	COG2208	phosphoserine phosphatase activity
GWQ54_RS11445	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GWQ54_RS11450	COG2362	D-Aminopeptidase
GWQ54_RS11455	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GWQ54_RS11465	COG1619	proteins homologs of microcin C7 resistance protein MccF
GWQ54_RS11475	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GWQ54_RS11500	COG0457	Tetratricopeptide repeat
GWQ54_RS11525	COG1595	DNA-templated transcription, initiation
GWQ54_RS11635	COG0531	amino acid
GWQ54_RS11695	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GWQ54_RS11735	COG5002	protein histidine kinase activity
GWQ54_RS11760	COG2154	pterin-4-alpha-carbinolamine dehydratase
GWQ54_RS11785	COG0656	L-ascorbic acid biosynthetic process
GWQ54_RS11830	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GWQ54_RS11840	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GWQ54_RS11865	COG1012	belongs to the aldehyde dehydrogenase family
GWQ54_RS11945	COG3291	Pkd domain containing protein
GWQ54_RS11955	COG4106	trans-aconitate 2-methyltransferase activity
GWQ54_RS11995	COG0137	argininosuccinate synthase activity
GWQ54_RS12005	COG1129	ABC transporter
GWQ54_RS12010	COG1879	ABC-type sugar transport system periplasmic component
GWQ54_RS12015	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GWQ54_RS12025	COG2814	Major facilitator Superfamily
GWQ54_RS12060	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
GWQ54_RS12085	COG0366	Alpha amylase catalytic
GWQ54_RS12090	COG3281	Trehalose synthase
GWQ54_RS12095	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GWQ54_RS12110	COG0297	glycogen (starch) synthase activity
GWQ54_RS12155	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GWQ54_RS12160	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GWQ54_RS12175	COG3511	phospholipase C
GWQ54_RS12180	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GWQ54_RS12225	COG3903	Transcriptional regulator
GWQ54_RS12225	COG3629	intracellular signal transduction
GWQ54_RS12240	COG1063	alcohol dehydrogenase
GWQ54_RS12245	COG0156	8-amino-7-oxononanoate synthase activity
GWQ54_RS12280	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
GWQ54_RS12295	COG3012	SEC-C Motif Domain Protein
GWQ54_RS12305	COG4413	Urea transporter
GWQ54_RS12350	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GWQ54_RS12410	COG1793	dna ligase
GWQ54_RS12425	COG1263	PTS System
GWQ54_RS12430	COG2188	Transcriptional regulator
GWQ54_RS12450	COG0488	(ABC) transporter
GWQ54_RS12470	COG1515	deoxyribonuclease V activity
GWQ54_RS12475	COG3268	Saccharopine dehydrogenase
GWQ54_RS12480	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GWQ54_RS12485	COG1960	acyl-CoA dehydrogenase activity
GWQ54_RS12490	COG0183	Belongs to the thiolase family
GWQ54_RS12495	COG1250	3-hydroxyacyl-CoA dehydrogenase
GWQ54_RS12495	COG1024	Enoyl-CoA hydratase
GWQ54_RS12510	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GWQ54_RS12530	COG2936	dipeptidyl-peptidase activity
GWQ54_RS12565	COG2183	response to ionizing radiation
GWQ54_RS12575	COG4977	sequence-specific DNA binding
GWQ54_RS12590	COG1024	Enoyl-CoA hydratase
GWQ54_RS12605	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GWQ54_RS12645	COG1134	teichoic acid transport
GWQ54_RS12650	COG1562	ergosterol biosynthetic process
GWQ54_RS12660	COG1233	COG1233 Phytoene dehydrogenase and related
GWQ54_RS12670	COG1657	PFAM Prenyltransferase squalene oxidase
GWQ54_RS12685	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GWQ54_RS12705	COG2365	Tyrosine phosphatase family
GWQ54_RS12725	COG2755	lipolytic protein G-D-S-L family
GWQ54_RS12735	COG0726	polysaccharide deacetylase
GWQ54_RS12745	COG3467	pyridoxamine 5'-phosphate
GWQ54_RS12795	COG1960	acyl-CoA dehydrogenase activity
GWQ54_RS12800	COG0673	inositol 2-dehydrogenase activity
GWQ54_RS12815	COG0583	DNA-binding transcription factor activity
GWQ54_RS12820	COG1028	Short-chain dehydrogenase reductase Sdr
GWQ54_RS12865	COG4106	trans-aconitate 2-methyltransferase activity
GWQ54_RS12880	COG0604	alcohol dehydrogenase
GWQ54_RS12900	COG1349	DNA-binding transcription factor activity
GWQ54_RS12905	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GWQ54_RS12920	COG0247	lactate metabolic process
GWQ54_RS12925	COG1139	Iron-sulfur cluster binding protein
GWQ54_RS12930	COG1556	Lactate utilization protein
GWQ54_RS12995	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GWQ54_RS13000	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GWQ54_RS13005	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GWQ54_RS13025	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GWQ54_RS13035	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GWQ54_RS13040	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GWQ54_RS13045	COG1028	Short-chain dehydrogenase reductase Sdr
GWQ54_RS13050	COG1024	Enoyl-CoA hydratase
GWQ54_RS13065	COG2124	cytochrome p450
GWQ54_RS13070	COG2814	Major facilitator Superfamily
GWQ54_RS13080	COG1028	Short-chain dehydrogenase reductase Sdr
GWQ54_RS13095	COG1846	Transcriptional regulator
GWQ54_RS13105	COG1309	transcriptional regulator
GWQ54_RS13125	COG1028	Short-chain dehydrogenase reductase Sdr
GWQ54_RS13135	COG1285	pathogenesis
GWQ54_RS13200	COG0671	phosphoesterase, PA-phosphatase related
GWQ54_RS13205	COG0586	Pfam SNARE associated Golgi protein
GWQ54_RS13225	COG2409	Drug exporters of the RND superfamily
GWQ54_RS13280	COG1366	Belongs to the anti-sigma-factor antagonist family
GWQ54_RS13295	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GWQ54_RS13315	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GWQ54_RS13340	COG0542	response to heat
GWQ54_RS13345	COG3537	Alpha-1,2-mannosidase
GWQ54_RS13365	COG1506	peptidase
GWQ54_RS13365	COG0823	Involved in the tonB-independent uptake of proteins
GWQ54_RS13390	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GWQ54_RS13410	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GWQ54_RS13415	COG3275	phosphorelay sensor kinase activity
GWQ54_RS13445	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GWQ54_RS13445	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GWQ54_RS13450	COG0726	polysaccharide deacetylase
GWQ54_RS13500	COG0583	DNA-binding transcription factor activity
GWQ54_RS13510	COG1053	succinate dehydrogenase
GWQ54_RS13515	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GWQ54_RS13520	COG3979	chitinase
GWQ54_RS13540	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GWQ54_RS13555	COG2182	Extracellular solute-binding protein
GWQ54_RS13585	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
GWQ54_RS13590	COG0121	glutamine amidotransferase
GWQ54_RS13595	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GWQ54_RS13600	COG3572	ergothioneine biosynthetic process
GWQ54_RS13615	COG3858	chitin binding
GWQ54_RS13620	COG0640	Transcriptional regulator
GWQ54_RS13625	COG3250	beta-galactosidase activity
GWQ54_RS13630	COG1940	carbohydrate kinase activity
GWQ54_RS13635	COG0531	amino acid
GWQ54_RS13640	COG2268	Band 7 protein
GWQ54_RS13655	COG4106	trans-aconitate 2-methyltransferase activity
GWQ54_RS13670	COG0596	Alpha beta hydrolase
GWQ54_RS13680	COG1609	Transcriptional regulator
GWQ54_RS13690	COG0183	Belongs to the thiolase family
GWQ54_RS13720	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GWQ54_RS13725	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GWQ54_RS13735	COG0438	transferase activity, transferring glycosyl groups
GWQ54_RS13750	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GWQ54_RS13780	COG1285	pathogenesis
GWQ54_RS13850	COG1917	Cupin 2, conserved barrel domain protein
GWQ54_RS13850	COG2207	Transcriptional regulator
GWQ54_RS13855	COG1028	Short-chain dehydrogenase reductase Sdr
GWQ54_RS13865	COG0346	lactoylglutathione lyase activity
GWQ54_RS13875	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
GWQ54_RS13875	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GWQ54_RS13880	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GWQ54_RS13900	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GWQ54_RS13925	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GWQ54_RS13940	COG0789	Transcriptional regulator
GWQ54_RS13975	COG1509	lysine 2,3-aminomutase activity
GWQ54_RS13980	COG4948	Mandelate Racemase Muconate Lactonizing
GWQ54_RS13985	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GWQ54_RS14000	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GWQ54_RS14005	COG1181	Belongs to the D-alanine--D-alanine ligase family
GWQ54_RS14020	COG1960	acyl-CoA dehydrogenase activity
GWQ54_RS14025	COG1024	Enoyl-CoA hydratase
GWQ54_RS14045	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GWQ54_RS14070	COG1366	Belongs to the anti-sigma-factor antagonist family
GWQ54_RS14075	COG1366	Belongs to the anti-sigma-factor antagonist family
GWQ54_RS14080	COG2172	sigma factor antagonist activity
GWQ54_RS14100	COG4251	negative regulation of phosphorylation
GWQ54_RS14105	COG0784	Response regulator, receiver
GWQ54_RS14130	COG0784	Response regulator, receiver
GWQ54_RS14135	COG4251	negative regulation of phosphorylation
GWQ54_RS14155	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GWQ54_RS14160	COG2378	regulation of single-species biofilm formation
GWQ54_RS14175	COG1366	Belongs to the anti-sigma-factor antagonist family
GWQ54_RS14205	COG2957	Belongs to the agmatine deiminase family
GWQ54_RS14210	COG2957	Belongs to the agmatine deiminase family
GWQ54_RS14225	COG0832	Belongs to the urease beta subunit family
GWQ54_RS14225	COG0831	urea catabolic process
GWQ54_RS14230	COG0804	urea catabolic process
GWQ54_RS14235	COG2957	Belongs to the agmatine deiminase family
GWQ54_RS14250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GWQ54_RS14265	COG2957	Belongs to the agmatine deiminase family
GWQ54_RS14280	COG2813	Specifically methylates the guanine in position
GWQ54_RS14335	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GWQ54_RS14360	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GWQ54_RS14395	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
GWQ54_RS14400	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GWQ54_RS14405	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GWQ54_RS14405	COG2080	2 iron, 2 sulfur cluster binding
GWQ54_RS14410	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GWQ54_RS14425	COG1940	carbohydrate kinase activity
GWQ54_RS14440	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GWQ54_RS14445	COG1116	anion transmembrane transporter activity
GWQ54_RS14450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GWQ54_RS14465	COG4044	May play a role in the intracellular transport of hydrophobic ligands
GWQ54_RS14470	COG0515	serine threonine protein kinase
GWQ54_RS14470	COG2815	serine threonine protein kinase
GWQ54_RS14570	COG1228	amidohydrolase
GWQ54_RS14575	COG1174	glycine betaine transport
GWQ54_RS14580	COG1174	glycine betaine transport
GWQ54_RS14595	COG1125	glycine betaine transport
GWQ54_RS14595	COG0517	IMP dehydrogenase activity
GWQ54_RS14600	COG2205	protein histidine kinase activity
GWQ54_RS14605	COG0745	RESPONSE REGULATOR receiver
GWQ54_RS14615	COG0577	efflux transmembrane transporter activity
GWQ54_RS14615	COG1136	(ABC) transporter
GWQ54_RS14620	COG1136	(ABC) transporter
GWQ54_RS14620	COG4591	ABC-type transport system involved in lipoprotein release permease component
GWQ54_RS14645	COG1024	Enoyl-CoA hydratase
GWQ54_RS14650	COG1028	Short-chain dehydrogenase reductase Sdr
GWQ54_RS14660	COG1960	acyl-CoA dehydrogenase activity
GWQ54_RS14665	COG1960	acyl-CoA dehydrogenase activity
GWQ54_RS14680	COG0601	transmembrane transport
GWQ54_RS14685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GWQ54_RS14690	COG0444	Belongs to the ABC transporter superfamily
GWQ54_RS14695	COG4608	Belongs to the ABC transporter superfamily
GWQ54_RS14760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GWQ54_RS14770	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GWQ54_RS14775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GWQ54_RS14780	COG0693	protein deglycase activity
GWQ54_RS14785	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
GWQ54_RS14820	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GWQ54_RS14865	COG1070	Carbohydrate kinase
GWQ54_RS14870	COG2115	Belongs to the xylose isomerase family
GWQ54_RS14875	COG1028	Short-chain dehydrogenase reductase Sdr
GWQ54_RS14900	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GWQ54_RS14910	COG3511	phospholipase C
GWQ54_RS14930	COG2890	protein-(glutamine-N5) methyltransferase activity
GWQ54_RS14940	COG5002	protein histidine kinase activity
GWQ54_RS14940	COG0784	Response regulator, receiver
GWQ54_RS14940	COG2205	protein histidine kinase activity
GWQ54_RS14965	COG1191	sigma factor activity
GWQ54_RS14985	COG0783	Belongs to the Dps family
GWQ54_RS14990	COG2080	2 iron, 2 sulfur cluster binding
GWQ54_RS14995	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GWQ54_RS15000	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GWQ54_RS15005	COG2770	Histidine kinase
GWQ54_RS15005	COG2208	phosphoserine phosphatase activity
GWQ54_RS15030	COG1032	radical SAM domain protein
GWQ54_RS15040	COG1295	ribonuclease BN
GWQ54_RS15055	COG1733	regulation of RNA biosynthetic process
GWQ54_RS15060	COG1595	DNA-templated transcription, initiation
GWQ54_RS15070	COG0477	Major facilitator Superfamily
GWQ54_RS15110	COG4221	oxidoreductase activity
GWQ54_RS15160	COG1846	Transcriptional regulator
GWQ54_RS15165	COG0477	Major facilitator Superfamily
GWQ54_RS15190	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GWQ54_RS15275	COG0242	peptide deformylase activity
GWQ54_RS15290	COG0662	Cupin 2, conserved barrel domain protein
GWQ54_RS15310	COG4067	protein conserved in archaea
GWQ54_RS15310	COG0189	ligase activity
GWQ54_RS15330	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GWQ54_RS15360	COG2208	phosphoserine phosphatase activity
GWQ54_RS15360	COG2770	Histidine kinase
GWQ54_RS15375	COG1846	Transcriptional regulator
GWQ54_RS15385	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GWQ54_RS15390	COG1064	alcohol dehydrogenase
GWQ54_RS15405	COG0277	FAD linked oxidase domain protein
GWQ54_RS15405	COG0247	lactate metabolic process
GWQ54_RS15410	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GWQ54_RS15420	COG1620	l-lactate permease
GWQ54_RS15435	COG0235	Class ii aldolase
GWQ54_RS15440	COG3395	kinase activity
GWQ54_RS15455	COG1082	Xylose isomerase domain protein TIM barrel
GWQ54_RS15460	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GWQ54_RS15480	COG2319	Wd-40 repeat
GWQ54_RS15480	COG4249	Peptidase C14 caspase catalytic subunit p20
GWQ54_RS15490	COG1819	glycosyl
GWQ54_RS15560	COG2197	response regulator
GWQ54_RS15585	COG1012	belongs to the aldehyde dehydrogenase family
GWQ54_RS15670	COG4251	negative regulation of phosphorylation
GWQ54_RS15675	COG0784	Response regulator, receiver
GWQ54_RS15705	COG1191	sigma factor activity
GWQ54_RS15735	COG1959	2 iron, 2 sulfur cluster binding
GWQ54_RS15735	COG1295	ribonuclease BN
GWQ54_RS15745	COG1191	sigma factor activity
GWQ54_RS15790	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GWQ54_RS15805	COG1366	Belongs to the anti-sigma-factor antagonist family
GWQ54_RS15810	COG1366	Belongs to the anti-sigma-factor antagonist family
GWQ54_RS15815	COG2172	sigma factor antagonist activity
GWQ54_RS15825	COG0784	Response regulator, receiver
GWQ54_RS15825	COG2198	Histidine kinase
GWQ54_RS15825	COG5002	protein histidine kinase activity
GWQ54_RS15830	COG0784	Response regulator, receiver
GWQ54_RS15915	COG0154	amidase activity
GWQ54_RS15970	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GWQ54_RS16045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GWQ54_RS16050	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GWQ54_RS16055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GWQ54_RS16060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GWQ54_RS16075	COG1309	transcriptional regulator
GWQ54_RS16145	COG2362	D-Aminopeptidase
GWQ54_RS16155	COG0076	glutamate decarboxylase activity
GWQ54_RS16190	COG1335	isochorismatase
GWQ54_RS16200	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GWQ54_RS16215	COG2318	DinB family
GWQ54_RS16240	COG0640	Transcriptional regulator
GWQ54_RS16265	COG0367	asparagine synthase
GWQ54_RS16325	COG1181	Belongs to the D-alanine--D-alanine ligase family
GWQ54_RS16470	COG2207	Transcriptional regulator
GWQ54_RS16485	COG2843	Capsule synthesis protein
GWQ54_RS16545	COG3629	intracellular signal transduction
GWQ54_RS16545	COG3903	Transcriptional regulator
GWQ54_RS16585	COG3486	L-lysine 6-monooxygenase (NADPH) activity
GWQ54_RS16590	COG0531	amino acid
GWQ54_RS16600	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GWQ54_RS16610	COG0456	acetyltransferase
GWQ54_RS16620	COG1280	lysine exporter protein (LysE YggA)
GWQ54_RS16630	COG0626	cystathionine gamma-synthase activity
GWQ54_RS16640	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GWQ54_RS16680	COG1335	isochorismatase
GWQ54_RS16695	COG0251	oxidation-reduction process
GWQ54_RS16735	COG0436	Aminotransferase
GWQ54_RS16745	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GWQ54_RS16760	COG1028	Short-chain dehydrogenase reductase Sdr
GWQ54_RS16850	COG3251	PFAM MbtH domain protein
GWQ54_RS16865	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GWQ54_RS16885	COG3483	tryptophan 2,3-dioxygenase activity
GWQ54_RS16900	COG2124	cytochrome p450
GWQ54_RS16935	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GWQ54_RS16950	COG0009	L-threonylcarbamoyladenylate synthase
GWQ54_RS16960	COG1309	transcriptional regulator
GWQ54_RS16965	COG1846	Transcriptional regulator
GWQ54_RS17055	COG0346	lactoylglutathione lyase activity
GWQ54_RS17085	COG0596	Alpha beta hydrolase
GWQ54_RS17105	COG1473	amidohydrolase
GWQ54_RS17155	COG1073	alpha beta
GWQ54_RS17170	COG0657	acetylesterase activity
GWQ54_RS17190	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GWQ54_RS17200	COG0438	transferase activity, transferring glycosyl groups
GWQ54_RS17210	COG0438	transferase activity, transferring glycosyl groups
GWQ54_RS17250	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GWQ54_RS17270	COG0477	Major facilitator Superfamily
GWQ54_RS17275	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GWQ54_RS17280	COG2205	protein histidine kinase activity
GWQ54_RS17285	COG0745	RESPONSE REGULATOR receiver
GWQ54_RS17340	COG2205	protein histidine kinase activity
GWQ54_RS17345	COG0745	RESPONSE REGULATOR receiver
GWQ54_RS17355	COG3976	FMN-binding domain protein
GWQ54_RS17355	COG0431	NADPH-dependent FMN reductase
GWQ54_RS17355	COG1053	succinate dehydrogenase
GWQ54_RS17395	COG1349	DNA-binding transcription factor activity
GWQ54_RS17410	COG0395	ABC-type sugar transport system, permease component
GWQ54_RS17415	COG1063	alcohol dehydrogenase
GWQ54_RS17460	COG1028	Short-chain dehydrogenase reductase Sdr
GWQ54_RS17465	COG4948	Mandelate Racemase Muconate Lactonizing
GWQ54_RS17470	COG1940	carbohydrate kinase activity
GWQ54_RS17475	COG2271	Major facilitator Superfamily
GWQ54_RS17485	COG0019	diaminopimelate decarboxylase activity
GWQ54_RS17515	COG0657	acetylesterase activity
GWQ54_RS17530	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
GWQ54_RS17570	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GWQ54_RS17580	COG1609	Transcriptional regulator
GWQ54_RS17590	COG0402	S-adenosylhomocysteine deaminase activity
GWQ54_RS17595	COG2233	PERMEase
GWQ54_RS17645	COG0583	DNA-binding transcription factor activity
GWQ54_RS17660	COG3629	intracellular signal transduction
GWQ54_RS17750	COG1733	regulation of RNA biosynthetic process
GWQ54_RS17790	COG3548	integral membrane protein
GWQ54_RS17810	COG0667	Aldo Keto reductase
GWQ54_RS17820	COG0667	Aldo Keto reductase
GWQ54_RS17870	COG1231	oxidoreductase activity
GWQ54_RS17925	COG0596	Alpha beta hydrolase
GWQ54_RS17940	COG1309	transcriptional regulator
GWQ54_RS17945	COG1028	Short-chain dehydrogenase reductase Sdr
GWQ54_RS17960	COG4191	Histidine kinase
GWQ54_RS17965	COG2814	Major facilitator Superfamily
GWQ54_RS17985	COG0659	secondary active sulfate transmembrane transporter activity
GWQ54_RS17995	COG0300	oxidoreductase activity
GWQ54_RS18020	COG2188	Transcriptional regulator
GWQ54_RS18025	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
GWQ54_RS18055	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GWQ54_RS18090	COG0667	Aldo Keto reductase
GWQ54_RS18140	COG2814	Major facilitator Superfamily
GWQ54_RS18150	COG1051	belongs to the nudix hydrolase family
GWQ54_RS18195	COG3033	Beta-eliminating lyase
GWQ54_RS18395	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GWQ54_RS18455	COG3344	reverse transcriptase
GWQ54_RS18585	COG3293	Transposase
GWQ54_RS18630	COG4974	Belongs to the 'phage' integrase family
GWQ54_RS18675	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GWQ54_RS18685	COG0326	Molecular chaperone. Has ATPase activity
GWQ54_RS18750	COG1295	ribonuclease BN
GWQ54_RS18825	COG0494	nUDIX hydrolase
GWQ54_RS18905	COG2815	serine threonine protein kinase
GWQ54_RS18905	COG0515	serine threonine protein kinase
GWQ54_RS18910	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GWQ54_RS18930	COG1132	(ABC) transporter
GWQ54_RS18940	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GWQ54_RS18960	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GWQ54_RS18980	COG2226	methyltransferase
GWQ54_RS18990	COG0667	Aldo Keto reductase
GWQ54_RS18995	COG1028	Short-chain dehydrogenase reductase Sdr
GWQ54_RS19000	COG1260	myo-inositol-1-phosphate synthase
GWQ54_RS19005	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GWQ54_RS19010	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
GWQ54_RS19020	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GWQ54_RS19025	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GWQ54_RS19035	COG0494	nUDIX hydrolase
GWQ54_RS19060	COG0583	DNA-binding transcription factor activity
GWQ54_RS19065	COG2208	phosphoserine phosphatase activity
GWQ54_RS19065	COG2770	Histidine kinase
GWQ54_RS19125	COG2409	Drug exporters of the RND superfamily
GWQ54_RS19130	COG1846	Transcriptional regulator
GWQ54_RS19140	COG0702	epimerase
GWQ54_RS19175	COG0142	geranyltranstransferase activity
GWQ54_RS19185	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
GWQ54_RS19185	COG0493	'glutamate synthase
GWQ54_RS19190	COG1595	DNA-templated transcription, initiation
GWQ54_RS19290	COG3251	PFAM MbtH domain protein
GWQ54_RS19310	COG2124	cytochrome p450
GWQ54_RS19325	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GWQ54_RS19395	COG1309	transcriptional regulator
GWQ54_RS19410	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GWQ54_RS19440	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GWQ54_RS19445	COG3046	protein related to deoxyribodipyrimidine photolyase
GWQ54_RS19470	COG3293	Transposase
GWQ54_RS19540	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
GWQ54_RS19625	COG0583	DNA-binding transcription factor activity
GWQ54_RS19645	COG4221	oxidoreductase activity
GWQ54_RS19670	COG1028	Short-chain dehydrogenase reductase Sdr
GWQ54_RS19740	COG1716	ATPase activity
GWQ54_RS19740	COG1131	(ABC) transporter
GWQ54_RS19740	COG0842	Transport permease protein
GWQ54_RS19750	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GWQ54_RS19765	COG2264	protein methyltransferase activity
GWQ54_RS19780	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GWQ54_RS19795	COG1309	transcriptional regulator
GWQ54_RS19825	COG1309	transcriptional regulator
GWQ54_RS19840	COG3158	transport of potassium into the cell
GWQ54_RS19875	COG4221	oxidoreductase activity
GWQ54_RS19900	COG3104	oligopeptide transport
GWQ54_RS19905	COG1461	Dihydroxyacetone kinase
GWQ54_RS19910	COG2376	Dihydroxyacetone kinase
GWQ54_RS19915	COG0371	Dehydrogenase
GWQ54_RS19955	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GWQ54_RS19965	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GWQ54_RS19970	COG1459	type II secretion system
GWQ54_RS19995	COG1228	amidohydrolase
GWQ54_RS20020	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
GWQ54_RS20085	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GWQ54_RS20110	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GWQ54_RS20120	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
GWQ54_RS20150	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
GWQ54_RS20170	COG0596	Alpha beta hydrolase
GWQ54_RS20175	COG4941	Belongs to the sigma-70 factor family
GWQ54_RS20180	COG3795	YCII-related domain
GWQ54_RS20195	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GWQ54_RS20220	COG3568	Endonuclease Exonuclease Phosphatase
GWQ54_RS20245	COG0596	Alpha beta hydrolase
GWQ54_RS20265	COG4989	oxidoreductase activity
GWQ54_RS20270	COG2226	methyltransferase
GWQ54_RS20270	COG1073	alpha beta
GWQ54_RS20275	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GWQ54_RS20280	COG1960	acyl-CoA dehydrogenase activity
GWQ54_RS20290	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GWQ54_RS20295	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GWQ54_RS20335	COG1064	alcohol dehydrogenase
GWQ54_RS20350	COG0483	inositol monophosphate 1-phosphatase activity
GWQ54_RS20370	COG0477	Major facilitator Superfamily
GWQ54_RS20380	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GWQ54_RS20405	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GWQ54_RS20455	COG4106	trans-aconitate 2-methyltransferase activity
GWQ54_RS20490	COG3629	intracellular signal transduction
GWQ54_RS20490	COG3903	Transcriptional regulator
GWQ54_RS20510	COG1408	metallophosphoesterase
GWQ54_RS20555	COG0778	Nitroreductase
GWQ54_RS20605	COG1063	alcohol dehydrogenase
GWQ54_RS20610	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GWQ54_RS20615	COG2226	methyltransferase
GWQ54_RS20640	COG0583	DNA-binding transcription factor activity
GWQ54_RS20645	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GWQ54_RS20675	COG1428	Deoxynucleoside kinase
GWQ54_RS20680	COG1921	L-seryl-tRNASec selenium transferase activity
GWQ54_RS20685	COG0028	Belongs to the TPP enzyme family
GWQ54_RS20690	COG0069	glutamate synthase activity
GWQ54_RS20700	COG2211	Major facilitator Superfamily
GWQ54_RS20710	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GWQ54_RS20715	COG0156	8-amino-7-oxononanoate synthase activity
GWQ54_RS20725	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GWQ54_RS20730	COG3962	Belongs to the TPP enzyme family
GWQ54_RS20735	COG0318	PFAM AMP-dependent synthetase and ligase
GWQ54_RS20745	COG3655	Transcriptional regulator
GWQ54_RS20750	COG1846	Transcriptional regulator
GWQ54_RS20785	COG1012	belongs to the aldehyde dehydrogenase family
GWQ54_RS20860	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GWQ54_RS20900	COG3848	Pyruvate phosphate dikinase
GWQ54_RS20900	COG0574	Belongs to the PEP-utilizing enzyme family
GWQ54_RS20910	COG0702	epimerase
GWQ54_RS20920	COG0667	Aldo Keto reductase
GWQ54_RS20975	COG4195	phage-related replication protein
GWQ54_RS21000	COG2205	protein histidine kinase activity
GWQ54_RS21015	COG0318	PFAM AMP-dependent synthetase and ligase
GWQ54_RS21035	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GWQ54_RS21060	COG4221	oxidoreductase activity
GWQ54_RS21090	COG1918	ferrous iron import across plasma membrane
GWQ54_RS21090	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GWQ54_RS21105	COG1733	regulation of RNA biosynthetic process
GWQ54_RS21110	COG2084	Dehydrogenase
GWQ54_RS21175	COG2208	phosphoserine phosphatase activity
GWQ54_RS21175	COG2770	Histidine kinase
GWQ54_RS21180	COG0596	Alpha beta hydrolase
GWQ54_RS21190	COG1846	Transcriptional regulator
GWQ54_RS21195	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GWQ54_RS21235	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GWQ54_RS21240	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GWQ54_RS21305	COG2267	carboxylic ester hydrolase activity
GWQ54_RS21320	COG2366	antibiotic biosynthetic process
GWQ54_RS21370	COG0500	methyltransferase
GWQ54_RS21385	COG0702	epimerase
GWQ54_RS21410	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GWQ54_RS21420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GWQ54_RS21450	COG1191	sigma factor activity
GWQ54_RS21465	COG0142	geranyltranstransferase activity
GWQ54_RS21485	COG0583	DNA-binding transcription factor activity
GWQ54_RS21555	COG2182	Extracellular solute-binding protein
GWQ54_RS21560	COG1175	transmembrane transport
GWQ54_RS21565	COG0395	ABC-type sugar transport system, permease component
GWQ54_RS21570	COG2723	6-phospho-beta-galactosidase activity
GWQ54_RS21625	COG0596	Alpha beta hydrolase
GWQ54_RS21650	COG1725	Transcriptional regulator
GWQ54_RS21660	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
GWQ54_RS21685	COG1595	DNA-templated transcription, initiation
GWQ54_RS21715	COG0783	Belongs to the Dps family
GWQ54_RS21725	COG3386	PFAM SMP-30 Gluconolaconase
GWQ54_RS21750	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GWQ54_RS21760	COG3237	CsbD-like
GWQ54_RS21785	COG1012	belongs to the aldehyde dehydrogenase family
GWQ54_RS21800	COG2066	Belongs to the glutaminase family
GWQ54_RS21830	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GWQ54_RS21860	COG0531	amino acid
GWQ54_RS21920	COG1011	Hydrolase
GWQ54_RS21945	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GWQ54_RS21950	COG0215	cysteine-tRNA ligase activity
GWQ54_RS21955	COG0671	phosphoesterase, PA-phosphatase related
GWQ54_RS21960	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GWQ54_RS21965	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GWQ54_RS21995	COG4941	Belongs to the sigma-70 factor family
GWQ54_RS22005	COG0789	Transcriptional regulator
GWQ54_RS22035	COG0142	geranyltranstransferase activity
GWQ54_RS22065	COG3537	Alpha-1,2-mannosidase
GWQ54_RS22070	COG1609	Transcriptional regulator
GWQ54_RS22080	COG1686	Belongs to the peptidase S11 family
GWQ54_RS22120	COG2205	protein histidine kinase activity
GWQ54_RS22125	COG0745	RESPONSE REGULATOR receiver
GWQ54_RS22140	COG0577	efflux transmembrane transporter activity
GWQ54_RS22140	COG1136	(ABC) transporter
GWQ54_RS22145	COG1136	(ABC) transporter
GWQ54_RS22145	COG0577	efflux transmembrane transporter activity
GWQ54_RS22150	COG0588	phosphoglycerate mutase activity
GWQ54_RS22155	COG0189	ligase activity
GWQ54_RS22160	COG0189	ligase activity
GWQ54_RS22170	COG2018	Roadblock/LC7 domain
GWQ54_RS22255	COG2197	response regulator
GWQ54_RS22260	COG4585	Histidine kinase
GWQ54_RS22280	COG3239	Fatty acid desaturase
GWQ54_RS22285	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GWQ54_RS22320	COG1012	belongs to the aldehyde dehydrogenase family
GWQ54_RS22335	COG1191	sigma factor activity
GWQ54_RS22355	COG0640	Transcriptional regulator
GWQ54_RS22380	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GWQ54_RS22385	COG1733	regulation of RNA biosynthetic process
GWQ54_RS22405	COG1028	Short-chain dehydrogenase reductase Sdr
GWQ54_RS22430	COG1028	Short-chain dehydrogenase reductase Sdr
GWQ54_RS22440	COG2197	response regulator
GWQ54_RS22445	COG5297	Belongs to the glycosyl hydrolase family 6
GWQ54_RS22445	COG3250	beta-galactosidase activity
GWQ54_RS22505	COG1028	Short-chain dehydrogenase reductase Sdr
GWQ54_RS22510	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GWQ54_RS22515	COG2815	serine threonine protein kinase
GWQ54_RS22515	COG0515	serine threonine protein kinase
GWQ54_RS22545	COG2124	cytochrome p450
GWQ54_RS22565	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GWQ54_RS22620	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
GWQ54_RS22620	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GWQ54_RS22625	COG3433	isochorismatase activity
GWQ54_RS22625	COG2226	methyltransferase
GWQ54_RS22625	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GWQ54_RS22655	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GWQ54_RS22660	COG0436	Aminotransferase
GWQ54_RS22695	COG4716	Myosin-crossreactive antigen
GWQ54_RS22755	COG0531	amino acid
GWQ54_RS22760	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GWQ54_RS22790	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GWQ54_RS22810	COG1028	Short-chain dehydrogenase reductase Sdr
GWQ54_RS22815	COG2080	2 iron, 2 sulfur cluster binding
GWQ54_RS22820	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GWQ54_RS22855	COG2124	cytochrome p450
GWQ54_RS22870	COG2124	cytochrome p450
GWQ54_RS22910	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GWQ54_RS22945	COG1132	(ABC) transporter
GWQ54_RS22955	COG0667	Aldo Keto reductase
GWQ54_RS22990	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GWQ54_RS22995	COG0009	L-threonylcarbamoyladenylate synthase
GWQ54_RS23035	COG0596	Alpha beta hydrolase
GWQ54_RS23035	COG0508	dehydrogenase complex catalyzes the overall conversion of
GWQ54_RS23040	COG0701	Predicted permease
GWQ54_RS23095	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GWQ54_RS23110	COG0572	uridine kinase
GWQ54_RS23155	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GWQ54_RS23190	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
GWQ54_RS23200	COG0328	RNA-DNA hybrid ribonuclease activity
GWQ54_RS23220	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GWQ54_RS23220	COG1796	DNA polymerase
GWQ54_RS23235	COG2319	Wd-40 repeat
GWQ54_RS23235	COG4249	Peptidase C14 caspase catalytic subunit p20
GWQ54_RS23265	COG2272	Belongs to the type-B carboxylesterase lipase family
GWQ54_RS23270	COG2814	Major facilitator Superfamily
GWQ54_RS23280	COG1764	response to oxidative stress
GWQ54_RS23285	COG1846	Transcriptional regulator
GWQ54_RS23290	COG1028	Short-chain dehydrogenase reductase Sdr
GWQ54_RS23325	COG0626	cystathionine gamma-synthase activity
GWQ54_RS23345	COG1012	belongs to the aldehyde dehydrogenase family
GWQ54_RS23355	COG3345	alpha-galactosidase
GWQ54_RS23360	COG2197	response regulator
GWQ54_RS23380	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
GWQ54_RS23385	COG0681	Belongs to the peptidase S26 family
GWQ54_RS23395	COG1191	sigma factor activity
GWQ54_RS23405	COG3469	chitinase activity
GWQ54_RS23410	COG1686	Belongs to the peptidase S11 family
GWQ54_RS23490	COG2124	cytochrome p450
GWQ54_RS23540	COG1672	PFAM Archaeal ATPase
GWQ54_RS23540	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
GWQ54_RS23545	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GWQ54_RS23590	COG0318	PFAM AMP-dependent synthetase and ligase
GWQ54_RS23600	COG2070	2-Nitropropane dioxygenase
GWQ54_RS23605	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GWQ54_RS23615	COG2815	serine threonine protein kinase
GWQ54_RS23615	COG0515	serine threonine protein kinase
GWQ54_RS23625	COG1960	acyl-CoA dehydrogenase activity
GWQ54_RS23640	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GWQ54_RS23650	COG2207	Transcriptional regulator
GWQ54_RS23655	COG2223	nitrite transmembrane transporter activity
GWQ54_RS23665	COG3189	MarR family transcriptional regulator
GWQ54_RS23680	COG1090	epimerase
GWQ54_RS23690	COG0254	rRNA binding
GWQ54_RS23695	COG2376	Dihydroxyacetone kinase
GWQ54_RS23700	COG1461	Dihydroxyacetone kinase
GWQ54_RS23715	COG1902	pentaerythritol trinitrate reductase activity
GWQ54_RS23715	COG0446	pyridine nucleotide-disulphide oxidoreductase
GWQ54_RS23740	COG2233	PERMEase
GWQ54_RS23770	COG1940	carbohydrate kinase activity
GWQ54_RS23775	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GWQ54_RS23775	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GWQ54_RS23780	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GWQ54_RS23790	COG3345	alpha-galactosidase
GWQ54_RS23795	COG2226	methyltransferase
GWQ54_RS23810	COG0768	penicillin binding
GWQ54_RS23825	COG2124	cytochrome p450
GWQ54_RS23845	COG2838	Isocitrate dehydrogenase
GWQ54_RS23860	COG0668	transmembrane transport
GWQ54_RS23890	COG0151	Belongs to the GarS family
GWQ54_RS23900	COG1733	regulation of RNA biosynthetic process
GWQ54_RS23905	COG0702	epimerase
GWQ54_RS23940	COG0385	Bile acid
GWQ54_RS23950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GWQ54_RS23980	COG4865	methylaspartate mutase activity
GWQ54_RS24005	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GWQ54_RS24010	COG0017	Asparaginyl-tRNA synthetase
GWQ54_RS24015	COG0069	glutamate synthase activity
GWQ54_RS24020	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GWQ54_RS24025	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GWQ54_RS24035	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
GWQ54_RS24040	COG2124	cytochrome p450
GWQ54_RS24045	COG3251	PFAM MbtH domain protein
GWQ54_RS24050	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GWQ54_RS24055	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GWQ54_RS24060	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GWQ54_RS24065	COG0165	Argininosuccinate lyase
GWQ54_RS24075	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GWQ54_RS24085	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GWQ54_RS24095	COG1733	regulation of RNA biosynthetic process
GWQ54_RS24100	COG0596	Alpha beta hydrolase
GWQ54_RS24115	COG2208	phosphoserine phosphatase activity
GWQ54_RS24115	COG2770	Histidine kinase
GWQ54_RS24160	COG1028	Short-chain dehydrogenase reductase Sdr
GWQ54_RS24185	COG1215	transferase activity, transferring glycosyl groups
GWQ54_RS24205	COG3217	Mosc domain protein beta barrel domain protein
GWQ54_RS24205	COG0633	Ferredoxin
GWQ54_RS24215	COG0464	growth
GWQ54_RS24225	COG1349	DNA-binding transcription factor activity
GWQ54_RS24235	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GWQ54_RS24240	COG0589	response to stress
GWQ54_RS24280	COG1940	carbohydrate kinase activity
GWQ54_RS24285	COG2223	nitrite transmembrane transporter activity
GWQ54_RS24300	COG2197	response regulator
GWQ54_RS24305	COG4585	Histidine kinase
GWQ54_RS24325	COG0395	ABC-type sugar transport system, permease component
GWQ54_RS24330	COG1175	transmembrane transport
GWQ54_RS24340	COG0445	tRNA wobble uridine modification
GWQ54_RS24355	COG1660	Displays ATPase and GTPase activities
GWQ54_RS24410	COG0395	ABC-type sugar transport system, permease component
GWQ54_RS24415	COG1175	transmembrane transport
GWQ54_RS24435	COG0515	serine threonine protein kinase
GWQ54_RS24435	COG2815	serine threonine protein kinase
GWQ54_RS24445	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GWQ54_RS24465	COG0204	Acyl-transferase
GWQ54_RS24500	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GWQ54_RS24510	COG0584	glycerophosphoryl diester phosphodiesterase
GWQ54_RS24535	COG0671	phosphoesterase, PA-phosphatase related
GWQ54_RS24545	COG1309	transcriptional regulator
GWQ54_RS24555	COG0640	Transcriptional regulator
GWQ54_RS24560	COG1902	pentaerythritol trinitrate reductase activity
GWQ54_RS24575	COG1309	transcriptional regulator
GWQ54_RS24585	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GWQ54_RS24600	COG2706	6-phosphogluconolactonase activity
GWQ54_RS24615	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GWQ54_RS24645	COG2274	protein secretion by the type I secretion system
GWQ54_RS24650	COG0501	Belongs to the peptidase M48B family
GWQ54_RS24685	COG0432	Pfam Uncharacterised protein family UPF0047
GWQ54_RS24690	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GWQ54_RS24695	COG1116	anion transmembrane transporter activity
GWQ54_RS24705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GWQ54_RS24720	COG1132	(ABC) transporter
GWQ54_RS24745	COG1132	(ABC) transporter
GWQ54_RS24750	COG1132	(ABC) transporter
GWQ54_RS24765	COG1946	Acyl-CoA thioesterase
GWQ54_RS24770	COG0386	Belongs to the glutathione peroxidase family
GWQ54_RS24775	COG1960	acyl-CoA dehydrogenase activity
GWQ54_RS24785	COG0242	peptide deformylase activity
GWQ54_RS24795	COG3442	glutamine amidotransferase
GWQ54_RS24800	COG0205	6-phosphofructokinase activity
GWQ54_RS24830	COG0829	nickel cation binding
GWQ54_RS24835	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GWQ54_RS24845	COG0804	urea catabolic process
GWQ54_RS24850	COG0832	Belongs to the urease beta subunit family
GWQ54_RS24855	COG0831	urea catabolic process
GWQ54_RS24870	COG0740	serine-type endopeptidase activity
GWQ54_RS24905	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GWQ54_RS24910	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GWQ54_RS24915	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GWQ54_RS24955	COG0456	acetyltransferase
GWQ54_RS24955	COG1214	PFAM Peptidase M22, glycoprotease
GWQ54_RS24960	COG0242	peptide deformylase activity
GWQ54_RS24965	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GWQ54_RS24990	COG4585	Histidine kinase
GWQ54_RS24995	COG2197	response regulator
GWQ54_RS25000	COG1940	carbohydrate kinase activity
GWQ54_RS25005	COG2188	Transcriptional regulator
GWQ54_RS25035	COG1522	sequence-specific DNA binding
GWQ54_RS25040	COG0419	ATPase involved in DNA repair
GWQ54_RS25045	COG0420	3'-5' exonuclease activity
GWQ54_RS25050	COG1739	Uncharacterized protein family UPF0029
GWQ54_RS25065	COG1832	CoA-binding protein
GWQ54_RS25070	COG2267	carboxylic ester hydrolase activity
GWQ54_RS25085	COG0641	radical SAM
GWQ54_RS25155	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GWQ54_RS25165	COG1968	undecaprenyl-diphosphatase activity
GWQ54_RS25200	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GWQ54_RS25210	COG2318	DinB family
GWQ54_RS25225	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GWQ54_RS25230	COG0747	negative chemotaxis
GWQ54_RS25235	COG1028	Short-chain dehydrogenase reductase Sdr
GWQ54_RS25275	COG0697	spore germination
GWQ54_RS25315	COG1695	Transcriptional regulator
GWQ54_RS25360	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GWQ54_RS25360	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GWQ54_RS25370	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GWQ54_RS25390	COG1716	ATPase activity
GWQ54_RS25410	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GWQ54_RS25440	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GWQ54_RS25455	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GWQ54_RS25460	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GWQ54_RS25475	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
GWQ54_RS25490	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GWQ54_RS25495	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GWQ54_RS25510	COG2018	Roadblock/LC7 domain
GWQ54_RS25545	COG2814	Major facilitator Superfamily
GWQ54_RS25550	COG4336	lyase activity
GWQ54_RS25555	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GWQ54_RS25560	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GWQ54_RS25565	COG1984	allophanate hydrolase subunit 2
GWQ54_RS25575	COG0438	transferase activity, transferring glycosyl groups
GWQ54_RS25605	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GWQ54_RS25610	COG2364	Membrane
GWQ54_RS25620	COG2270	Major facilitator Superfamily
GWQ54_RS25635	COG0463	Glycosyl transferase, family 2
GWQ54_RS25665	COG1960	acyl-CoA dehydrogenase activity
GWQ54_RS25675	COG1309	transcriptional regulator
GWQ54_RS25730	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GWQ54_RS25735	COG0140	phosphoribosyl-ATP diphosphatase activity
GWQ54_RS25740	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GWQ54_RS25745	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GWQ54_RS25745	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GWQ54_RS25750	COG3201	nicotinamide mononucleotide transporter
GWQ54_RS25770	COG1940	carbohydrate kinase activity
GWQ54_RS25770	COG1846	Transcriptional regulator
GWQ54_RS25775	COG0738	Major facilitator superfamily
GWQ54_RS25780	COG2233	PERMEase
GWQ54_RS25800	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GWQ54_RS25810	COG0531	amino acid
GWQ54_RS25825	COG2732	(Barnase) inhibitor
GWQ54_RS25835	COG1793	dna ligase
GWQ54_RS25850	COG2390	Transcriptional regulator
GWQ54_RS25855	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GWQ54_RS25865	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GWQ54_RS25880	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GWQ54_RS25895	COG0194	GDP metabolic process
GWQ54_RS25905	COG0284	orotidine-5'-phosphate decarboxylase activity
GWQ54_RS25910	COG0167	dihydroorotate dehydrogenase activity
GWQ54_RS25915	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GWQ54_RS25920	COG0505	Belongs to the CarA family
GWQ54_RS25930	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GWQ54_RS25935	COG0540	Belongs to the ATCase OTCase family
GWQ54_RS25940	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GWQ54_RS25950	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GWQ54_RS25955	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GWQ54_RS25960	COG0006	proline dipeptidase activity
GWQ54_RS25970	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GWQ54_RS25975	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GWQ54_RS25980	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GWQ54_RS25985	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GWQ54_RS25990	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GWQ54_RS25995	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GWQ54_RS26000	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GWQ54_RS26005	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GWQ54_RS26025	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GWQ54_RS26055	COG0124	histidyl-tRNA synthetase
GWQ54_RS26065	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GWQ54_RS26070	COG1196	nuclear chromosome segregation
GWQ54_RS26090	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GWQ54_RS26095	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GWQ54_RS26100	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GWQ54_RS26105	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GWQ54_RS26115	COG2255	four-way junction helicase activity
GWQ54_RS26120	COG0632	four-way junction helicase activity
GWQ54_RS26125	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GWQ54_RS26130	COG0217	transcriptional regulatory protein
GWQ54_RS26135	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
GWQ54_RS26140	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
GWQ54_RS26150	COG0438	transferase activity, transferring glycosyl groups
GWQ54_RS26155	COG1560	Kdo2-lipid A biosynthetic process
GWQ54_RS26160	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GWQ54_RS26180	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GWQ54_RS26195	COG5002	protein histidine kinase activity
GWQ54_RS26195	COG2176	DNA-directed DNA polymerase activity
GWQ54_RS26255	COG0512	Glutamine amidotransferase of anthranilate synthase
GWQ54_RS26255	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GWQ54_RS26305	COG1648	precorrin-2 dehydrogenase activity
GWQ54_RS26305	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GWQ54_RS26310	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GWQ54_RS26325	COG1464	Belongs to the NlpA lipoprotein family
GWQ54_RS26330	COG2011	ABC-type metal ion transport system permease component
GWQ54_RS26335	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GWQ54_RS26370	COG0318	PFAM AMP-dependent synthetase and ligase
GWQ54_RS26370	COG0204	Acyl-transferase
GWQ54_RS26375	COG0477	Major facilitator Superfamily
GWQ54_RS26385	COG0165	Argininosuccinate lyase
GWQ54_RS26395	COG1438	arginine binding
GWQ54_RS26400	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GWQ54_RS26405	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GWQ54_RS26410	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GWQ54_RS26415	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GWQ54_RS26425	COG1595	DNA-templated transcription, initiation
GWQ54_RS26430	COG1252	NADH dehydrogenase
GWQ54_RS26435	COG4941	Belongs to the sigma-70 factor family
GWQ54_RS26445	COG0110	maltose O-acetyltransferase activity
GWQ54_RS26460	COG0697	spore germination
GWQ54_RS26465	COG1649	PFAM Uncharacterised BCR, COG1649
GWQ54_RS26480	COG1051	belongs to the nudix hydrolase family
GWQ54_RS26495	COG0072	phenylalanine-tRNA ligase activity
GWQ54_RS26495	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GWQ54_RS26500	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GWQ54_RS26505	COG5002	protein histidine kinase activity
GWQ54_RS26510	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GWQ54_RS26515	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GWQ54_RS26520	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GWQ54_RS26525	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GWQ54_RS26570	COG1012	belongs to the aldehyde dehydrogenase family
GWQ54_RS26575	COG0174	glutamine synthetase
GWQ54_RS26585	COG1113	amino acid transport
GWQ54_RS26590	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GWQ54_RS26630	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GWQ54_RS26660	COG2409	Drug exporters of the RND superfamily
GWQ54_RS26670	COG2197	response regulator
GWQ54_RS26700	COG0805	protein transport
GWQ54_RS26705	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GWQ54_RS26725	COG2378	regulation of single-species biofilm formation
GWQ54_RS26735	COG0545	Peptidyl-prolyl cis-trans isomerase
GWQ54_RS26740	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
GWQ54_RS26750	COG1609	Transcriptional regulator
GWQ54_RS26755	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
GWQ54_RS26760	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
GWQ54_RS26775	COG4122	O-methyltransferase activity
GWQ54_RS26780	COG1222	aaa ATPase
GWQ54_RS26800	COG0517	IMP dehydrogenase activity
GWQ54_RS26800	COG1994	Peptidase M50
GWQ54_RS26810	COG2197	response regulator
GWQ54_RS26815	COG4166	transmembrane transport
GWQ54_RS26820	COG0747	negative chemotaxis
GWQ54_RS26830	COG1410	methionine synthase
GWQ54_RS26830	COG0646	methionine synthase
GWQ54_RS26835	COG1414	Transcriptional regulator
GWQ54_RS26840	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GWQ54_RS26845	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GWQ54_RS26850	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GWQ54_RS26855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GWQ54_RS26860	COG2186	Transcriptional regulator
GWQ54_RS26870	COG1012	belongs to the aldehyde dehydrogenase family
GWQ54_RS26890	COG0215	cysteine-tRNA ligase activity
GWQ54_RS26910	COG0598	Magnesium transport protein CorA
GWQ54_RS26920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GWQ54_RS26925	COG0667	Aldo Keto reductase
GWQ54_RS26955	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GWQ54_RS26965	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GWQ54_RS26970	COG0564	pseudouridine synthase activity
GWQ54_RS26975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GWQ54_RS27000	COG1113	amino acid transport
GWQ54_RS27005	COG2186	Transcriptional regulator
GWQ54_RS27010	COG3265	gluconokinase activity
GWQ54_RS27035	COG3573	Dehydrogenase
GWQ54_RS27040	COG0697	spore germination
GWQ54_RS27055	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GWQ54_RS27060	COG2149	membrane
GWQ54_RS27075	COG1960	acyl-CoA dehydrogenase activity
GWQ54_RS27085	COG0318	PFAM AMP-dependent synthetase and ligase
GWQ54_RS27095	COG3876	Protein conserved in bacteria
GWQ54_RS27140	COG1960	acyl-CoA dehydrogenase activity
GWQ54_RS27160	COG2851	Citrate transporter
GWQ54_RS27165	COG0243	molybdopterin cofactor binding
GWQ54_RS27170	COG1309	transcriptional regulator
GWQ54_RS27175	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
GWQ54_RS27180	COG2188	Transcriptional regulator
GWQ54_RS27195	COG1720	tRNA m6t6A37 methyltransferase activity
GWQ54_RS27215	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GWQ54_RS27225	COG0515	serine threonine protein kinase
GWQ54_RS27230	COG2755	lipolytic protein G-D-S-L family
GWQ54_RS27270	COG1725	Transcriptional regulator
GWQ54_RS27280	COG2226	methyltransferase
GWQ54_RS27305	COG1028	Short-chain dehydrogenase reductase Sdr
GWQ54_RS27320	COG0587	DNA-directed DNA polymerase activity
GWQ54_RS27335	COG1454	alcohol dehydrogenase
GWQ54_RS27335	COG1012	belongs to the aldehyde dehydrogenase family
GWQ54_RS27340	COG0330	HflC and HflK could
GWQ54_RS27350	COG3903	Transcriptional regulator
GWQ54_RS27350	COG3629	intracellular signal transduction
GWQ54_RS27365	COG0641	radical SAM
GWQ54_RS27395	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GWQ54_RS27400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GWQ54_RS27405	COG1126	abc transporter atp-binding protein
GWQ54_RS27420	COG0765	amino acid transport
GWQ54_RS27430	COG1799	cell septum assembly
GWQ54_RS27435	COG1960	acyl-CoA dehydrogenase activity
GWQ54_RS27440	COG0477	Major facilitator Superfamily
GWQ54_RS27445	COG0671	phosphoesterase, PA-phosphatase related
GWQ54_RS27465	COG0438	transferase activity, transferring glycosyl groups
GWQ54_RS27485	COG1160	GTP binding
GWQ54_RS27495	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GWQ54_RS27530	COG1397	ADP-ribosylglycohydrolase
GWQ54_RS27540	COG1187	pseudouridine synthase activity
GWQ54_RS27545	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GWQ54_RS27550	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GWQ54_RS27565	COG0686	Belongs to the AlaDH PNT family
GWQ54_RS27575	COG0494	nUDIX hydrolase
GWQ54_RS27580	COG0504	CTP synthase activity
GWQ54_RS27585	COG3387	PFAM Glycoside hydrolase 15-related
GWQ54_RS27595	COG0297	glycogen (starch) synthase activity
GWQ54_RS27600	COG0497	DNA recombination
GWQ54_RS27610	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GWQ54_RS27630	COG1120	ATPase activity
GWQ54_RS27635	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GWQ54_RS27640	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GWQ54_RS27645	COG0647	UMP catabolic process
GWQ54_RS27680	COG2094	Belongs to the DNA glycosylase MPG family
GWQ54_RS27690	COG1881	PFAM PEBP family protein
GWQ54_RS27715	COG1119	ATPase activity
GWQ54_RS27730	COG2197	response regulator
GWQ54_RS27735	COG4585	Histidine kinase
GWQ54_RS27740	COG1028	Short-chain dehydrogenase reductase Sdr
GWQ54_RS27755	COG1716	ATPase activity
GWQ54_RS27755	COG1131	(ABC) transporter
GWQ54_RS27755	COG0842	Transport permease protein
GWQ54_RS27765	COG3830	Belongs to the UPF0237 family
GWQ54_RS27765	COG0560	Phosphoserine phosphatase
GWQ54_RS27770	COG0588	phosphoglycerate mutase activity
GWQ54_RS27785	COG2186	Transcriptional regulator
GWQ54_RS27795	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GWQ54_RS27800	COG1028	Short-chain dehydrogenase reductase Sdr
GWQ54_RS27815	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GWQ54_RS27835	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GWQ54_RS27840	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GWQ54_RS27855	COG1063	alcohol dehydrogenase
GWQ54_RS27910	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GWQ54_RS27925	COG3387	PFAM Glycoside hydrolase 15-related
GWQ54_RS27965	COG1024	Enoyl-CoA hydratase
GWQ54_RS27975	COG0488	(ABC) transporter
GWQ54_RS28005	COG0235	Class ii aldolase
GWQ54_RS28025	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
GWQ54_RS28030	COG1492	cobalamin metabolic process
GWQ54_RS28045	COG1797	cobyrinic acid a,c-diamide synthase activity
GWQ54_RS28075	COG0456	acetyltransferase
GWQ54_RS28090	COG5285	phytanoyl-CoA dioxygenase
GWQ54_RS28105	COG1902	pentaerythritol trinitrate reductase activity
GWQ54_RS28110	COG1846	Transcriptional regulator
GWQ54_RS28130	COG0477	Major facilitator Superfamily
GWQ54_RS28145	COG1414	Transcriptional regulator
GWQ54_RS28150	COG4585	Histidine kinase
GWQ54_RS28155	COG2197	response regulator
GWQ54_RS28160	COG0768	penicillin binding
GWQ54_RS28175	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GWQ54_RS28180	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GWQ54_RS28195	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GWQ54_RS28225	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GWQ54_RS28230	COG2171	N-acyltransferase activity
GWQ54_RS28250	COG3226	Transcriptional regulator
GWQ54_RS28265	COG2151	metal-sulfur cluster biosynthetic enzyme
GWQ54_RS28270	COG0822	iron-sulfur transferase activity
GWQ54_RS28275	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GWQ54_RS28280	COG0396	ATPase activity
GWQ54_RS28290	COG0719	Fe-S assembly protein
GWQ54_RS28305	COG2746	aminoglycoside 3-N-acetyltransferase activity
GWQ54_RS28310	COG2116	formate transmembrane transporter activity
GWQ54_RS28315	COG1131	(ABC) transporter
GWQ54_RS28340	COG0109	protoheme IX farnesyltransferase activity
GWQ54_RS28350	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GWQ54_RS28365	COG0363	glucosamine-6-phosphate deaminase activity
GWQ54_RS28370	COG0166	Belongs to the GPI family
GWQ54_RS28380	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GWQ54_RS28390	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GWQ54_RS28400	COG1481	regulation of sporulation
GWQ54_RS28405	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GWQ54_RS28410	COG1660	Displays ATPase and GTPase activities
GWQ54_RS28415	COG0322	excinuclease ABC activity
GWQ54_RS28435	COG2146	nitrite reductase [NAD(P)H] activity
GWQ54_RS28445	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GWQ54_RS28460	COG0477	Major facilitator Superfamily
GWQ54_RS28480	COG0556	nucleotide-excision repair
GWQ54_RS28490	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GWQ54_RS28505	COG2313	pseudouridylate synthase activity
GWQ54_RS28530	COG0477	Major facilitator Superfamily
GWQ54_RS28550	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GWQ54_RS28595	COG0237	dephospho-CoA kinase activity
GWQ54_RS28610	COG2226	methyltransferase
GWQ54_RS28615	COG1643	Atp-dependent helicase
GWQ54_RS28645	COG2050	protein possibly involved in aromatic compounds catabolism
GWQ54_RS28660	COG0559	Belongs to the binding-protein-dependent transport system permease family
GWQ54_RS28700	COG2968	Membrane
GWQ54_RS28705	COG0737	Belongs to the 5'-nucleotidase family
GWQ54_RS28725	COG0287	Prephenate dehydrogenase
GWQ54_RS28725	COG1605	Chorismate mutase
GWQ54_RS28780	COG0366	Alpha amylase catalytic
GWQ54_RS28780	COG1470	cell adhesion involved in biofilm formation
GWQ54_RS28785	COG0076	glutamate decarboxylase activity
GWQ54_RS28815	COG3851	Histidine kinase
GWQ54_RS28820	COG2197	response regulator
GWQ54_RS28835	COG3833	ABC-type maltose transport systems, permease component
GWQ54_RS28845	COG3842	ATPase activity
GWQ54_RS28850	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GWQ54_RS28855	COG2186	Transcriptional regulator
GWQ54_RS28870	COG1028	Short-chain dehydrogenase reductase Sdr
GWQ54_RS28875	COG1028	Short-chain dehydrogenase reductase Sdr
GWQ54_RS28880	COG1024	Enoyl-CoA hydratase
GWQ54_RS28935	COG1278	Cold shock
GWQ54_RS28940	COG0183	Belongs to the thiolase family
GWQ54_RS28945	COG1309	transcriptional regulator
GWQ54_RS28950	COG1028	Short-chain dehydrogenase reductase Sdr
GWQ54_RS28955	COG1960	acyl-CoA dehydrogenase activity
GWQ54_RS28960	COG1960	acyl-CoA dehydrogenase activity
GWQ54_RS28965	COG4221	oxidoreductase activity
GWQ54_RS28980	COG2304	oxidoreductase activity
GWQ54_RS29000	COG0069	glutamate synthase activity
GWQ54_RS29000	COG0070	glutamate synthase
GWQ54_RS29000	COG0067	glutamate synthase
GWQ54_RS29010	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GWQ54_RS29015	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GWQ54_RS29025	COG0159	tryptophan synthase activity
GWQ54_RS29030	COG0133	tryptophan synthase activity
GWQ54_RS29035	COG0134	indole-3-glycerol-phosphate synthase activity
GWQ54_RS29060	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GWQ54_RS29065	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GWQ54_RS29085	COG0107	imidazoleglycerol-phosphate synthase activity
GWQ54_RS29090	COG0251	oxidation-reduction process
GWQ54_RS29095	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GWQ54_RS29100	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GWQ54_RS29110	COG0131	Imidazoleglycerol-phosphate dehydratase
GWQ54_RS29115	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GWQ54_RS29120	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GWQ54_RS29135	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GWQ54_RS29160	COG1432	Conserved Protein
GWQ54_RS29170	COG0587	DNA-directed DNA polymerase activity
GWQ54_RS29215	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GWQ54_RS29225	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GWQ54_RS29240	COG1799	cell septum assembly
GWQ54_RS29245	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GWQ54_RS29260	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GWQ54_RS29265	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GWQ54_RS29275	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GWQ54_RS29280	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GWQ54_RS29290	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GWQ54_RS29305	COG0275	rRNA processing
GWQ54_RS29315	COG0714	Associated with various cellular activities
GWQ54_RS29345	COG1129	ABC transporter
GWQ54_RS29355	COG1309	transcriptional regulator
GWQ54_RS29365	COG1233	COG1233 Phytoene dehydrogenase and related
GWQ54_RS29380	COG0352	thiamine-phosphate diphosphorylase activity
GWQ54_RS29395	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GWQ54_RS29395	COG2022	thiamine diphosphate biosynthetic process
GWQ54_RS29405	COG2022	thiamine diphosphate biosynthetic process
GWQ54_RS29410	COG2815	serine threonine protein kinase
GWQ54_RS29410	COG0515	serine threonine protein kinase
GWQ54_RS29415	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GWQ54_RS29420	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GWQ54_RS29425	COG2193	ferroxidase activity
GWQ54_RS29435	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
GWQ54_RS29455	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GWQ54_RS29460	COG0205	6-phosphofructokinase activity
GWQ54_RS29465	COG2197	response regulator
GWQ54_RS29470	COG4585	Histidine kinase
GWQ54_RS29495	COG1940	carbohydrate kinase activity
GWQ54_RS29505	COG0003	Pfam Anion-transporting ATPase
GWQ54_RS29520	COG1022	Amp-dependent synthetase and ligase
GWQ54_RS29525	COG0438	transferase activity, transferring glycosyl groups
GWQ54_RS29540	COG0791	NLP P60 protein
GWQ54_RS29540	COG0741	lytic transglycosylase activity
GWQ54_RS29570	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GWQ54_RS29575	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GWQ54_RS29580	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GWQ54_RS29585	COG0723	plastoquinol--plastocyanin reductase activity
GWQ54_RS29590	COG2010	Cytochrome c
GWQ54_RS29595	COG1845	cytochrome c oxidase, subunit III
GWQ54_RS29605	COG1376	ErfK ybiS ycfS ynhG family protein
GWQ54_RS29615	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GWQ54_RS29620	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GWQ54_RS29630	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GWQ54_RS29650	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GWQ54_RS29655	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GWQ54_RS29660	COG2197	response regulator
GWQ54_RS29685	COG2226	methyltransferase
GWQ54_RS29690	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GWQ54_RS29705	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GWQ54_RS29710	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GWQ54_RS29710	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GWQ54_RS29725	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GWQ54_RS29745	COG0438	transferase activity, transferring glycosyl groups
GWQ54_RS29755	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GWQ54_RS29760	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GWQ54_RS29765	COG0508	dehydrogenase complex catalyzes the overall conversion of
GWQ54_RS29775	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GWQ54_RS29790	COG2186	Transcriptional regulator
GWQ54_RS29810	COG1028	Short-chain dehydrogenase reductase Sdr
GWQ54_RS29850	COG0321	lipoyl(octanoyl) transferase activity
GWQ54_RS29855	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GWQ54_RS29885	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
GWQ54_RS29910	COG0745	RESPONSE REGULATOR receiver
GWQ54_RS29915	COG4585	Histidine kinase
GWQ54_RS29920	COG2197	response regulator
GWQ54_RS29925	COG2813	Specifically methylates the guanine in position
GWQ54_RS29945	COG2365	Tyrosine phosphatase family
GWQ54_RS29985	COG0583	DNA-binding transcription factor activity
GWQ54_RS30005	COG0366	Alpha amylase catalytic
GWQ54_RS30010	COG3833	ABC-type maltose transport systems, permease component
GWQ54_RS30015	COG1175	transmembrane transport
GWQ54_RS30020	COG2182	Extracellular solute-binding protein
GWQ54_RS30025	COG0366	Alpha amylase catalytic
GWQ54_RS30030	COG1609	Transcriptional regulator
GWQ54_RS30040	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GWQ54_RS30050	COG3594	Acyltransferase
GWQ54_RS30055	COG3511	phospholipase C
GWQ54_RS30075	COG0174	glutamine synthetase
GWQ54_RS30120	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GWQ54_RS30120	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GWQ54_RS30135	COG0477	Major facilitator Superfamily
GWQ54_RS30140	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GWQ54_RS30160	COG1994	Peptidase M50
GWQ54_RS30215	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GWQ54_RS30220	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GWQ54_RS30225	COG1120	ATPase activity
GWQ54_RS30235	COG2837	iron assimilation
GWQ54_RS30240	COG0672	)-iron permease
GWQ54_RS30255	COG1834	amidinotransferase
GWQ54_RS30265	COG2814	Major facilitator Superfamily
GWQ54_RS30275	COG0384	phenazine biosynthesis protein PhzF
GWQ54_RS30300	COG0789	Transcriptional regulator
GWQ54_RS30310	COG0557	exoribonuclease II activity
GWQ54_RS30315	COG3022	response to hydroperoxide
GWQ54_RS30320	COG0800	Aldolase
GWQ54_RS30335	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GWQ54_RS30340	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GWQ54_RS30355	COG1028	Short-chain dehydrogenase reductase Sdr
GWQ54_RS30365	COG2030	dehydratase
GWQ54_RS30370	COG1131	(ABC) transporter
GWQ54_RS30380	COG4585	Histidine kinase
GWQ54_RS30385	COG2197	response regulator
GWQ54_RS30395	COG0183	Belongs to the thiolase family
GWQ54_RS30400	COG1960	acyl-CoA dehydrogenase activity
GWQ54_RS30420	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GWQ54_RS30440	COG0438	transferase activity, transferring glycosyl groups
GWQ54_RS30445	COG1309	transcriptional regulator
GWQ54_RS30480	COG3845	ABC transporter
GWQ54_RS30500	COG0183	Belongs to the thiolase family
GWQ54_RS30505	COG2124	cytochrome p450
GWQ54_RS30565	COG2259	Doxx family
GWQ54_RS30590	COG0598	Magnesium transport protein CorA
GWQ54_RS30605	COG0477	Major facilitator Superfamily
GWQ54_RS30635	COG2186	Transcriptional regulator
GWQ54_RS30640	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GWQ54_RS30660	COG1358	cellular component organization or biogenesis
GWQ54_RS30705	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GWQ54_RS30715	COG0477	Major facilitator Superfamily
GWQ54_RS30720	COG1309	transcriptional regulator
GWQ54_RS30735	COG4585	Histidine kinase
GWQ54_RS30740	COG2197	response regulator
GWQ54_RS30755	COG0667	Aldo Keto reductase
GWQ54_RS30760	COG0789	Transcriptional regulator
GWQ54_RS30770	COG1741	Belongs to the pirin family
GWQ54_RS30785	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GWQ54_RS30790	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GWQ54_RS30795	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GWQ54_RS30815	COG1309	transcriptional regulator
GWQ54_RS30845	COG2267	carboxylic ester hydrolase activity
GWQ54_RS30850	COG1764	response to oxidative stress
GWQ54_RS30855	COG2130	NADP-dependent
GWQ54_RS30860	COG1846	Transcriptional regulator
GWQ54_RS30885	COG0318	PFAM AMP-dependent synthetase and ligase
GWQ54_RS30890	COG0825	malonyl-CoA metabolic process
GWQ54_RS30890	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GWQ54_RS30930	COG1070	Carbohydrate kinase
GWQ54_RS30945	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GWQ54_RS30950	COG0358	DNA primase activity
GWQ54_RS30960	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GWQ54_RS30975	COG2949	membrane
GWQ54_RS30995	COG2205	protein histidine kinase activity
GWQ54_RS31050	COG2146	nitrite reductase [NAD(P)H] activity
GWQ54_RS31050	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GWQ54_RS31060	COG1309	transcriptional regulator
GWQ54_RS31065	COG1028	Short-chain dehydrogenase reductase Sdr
GWQ54_RS31070	COG1028	Short-chain dehydrogenase reductase Sdr
GWQ54_RS31080	COG0531	amino acid
GWQ54_RS31085	COG2182	Extracellular solute-binding protein
GWQ54_RS31095	COG0395	ABC-type sugar transport system, permease component
GWQ54_RS31105	COG0574	Belongs to the PEP-utilizing enzyme family
GWQ54_RS31105	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GWQ54_RS31125	COG0477	Major facilitator Superfamily
GWQ54_RS31135	COG0667	Aldo Keto reductase
GWQ54_RS31150	COG2197	response regulator
GWQ54_RS31165	COG0423	glycine-tRNA ligase activity
GWQ54_RS31170	COG0803	Belongs to the bacterial solute-binding protein 9 family
GWQ54_RS31170	COG3443	Belongs to the bacterial solute-binding protein 9 family
GWQ54_RS31175	COG1121	(ABC) transporter
GWQ54_RS31180	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GWQ54_RS31190	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GWQ54_RS31195	COG1381	Involved in DNA repair and RecF pathway recombination
GWQ54_RS31205	COG2197	response regulator
GWQ54_RS31210	COG4585	Histidine kinase
GWQ54_RS31215	COG2409	Drug exporters of the RND superfamily
GWQ54_RS31240	COG0477	Major facilitator Superfamily
GWQ54_RS31245	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GWQ54_RS31270	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GWQ54_RS31310	COG2315	Protein conserved in bacteria
GWQ54_RS31320	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GWQ54_RS31330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GWQ54_RS31335	COG4948	Mandelate Racemase Muconate Lactonizing
GWQ54_RS31345	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GWQ54_RS31350	COG1234	tRNA 3'-trailer cleavage
GWQ54_RS31355	COG0537	adenosine 5'-monophosphoramidase activity
GWQ54_RS31375	COG0484	heat shock protein binding
GWQ54_RS31380	COG1420	regulation of RNA biosynthetic process
GWQ54_RS31415	COG1022	Amp-dependent synthetase and ligase
GWQ54_RS31420	COG0481	GTPase activity
GWQ54_RS31425	COG0268	Binds directly to 16S ribosomal RNA
GWQ54_RS31440	COG0318	PFAM AMP-dependent synthetase and ligase
GWQ54_RS31450	COG2197	response regulator
GWQ54_RS31455	COG4585	Histidine kinase
GWQ54_RS31465	COG4585	Histidine kinase
GWQ54_RS31490	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
GWQ54_RS31495	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
GWQ54_RS31500	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GWQ54_RS31505	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GWQ54_RS31540	COG0667	Aldo Keto reductase
GWQ54_RS31575	COG1819	glycosyl
GWQ54_RS31580	COG1131	(ABC) transporter
GWQ54_RS31600	COG1819	glycosyl
GWQ54_RS31610	COG2814	Major facilitator Superfamily
GWQ54_RS31620	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GWQ54_RS31625	COG0318	PFAM AMP-dependent synthetase and ligase
GWQ54_RS31635	COG0431	NADPH-dependent FMN reductase
GWQ54_RS31655	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
GWQ54_RS31680	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GWQ54_RS31700	COG2353	YceI-like domain
GWQ54_RS31715	COG1555	photosystem II stabilization
GWQ54_RS31715	COG1596	polysaccharide export
GWQ54_RS31720	COG1307	EDD domain protein, DegV family
GWQ54_RS31730	COG0495	leucyl-tRNA aminoacylation
GWQ54_RS31770	COG0588	phosphoglycerate mutase activity
GWQ54_RS31775	COG0799	negative regulation of ribosome biogenesis
GWQ54_RS31785	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GWQ54_RS31800	COG0501	Belongs to the peptidase M48B family
GWQ54_RS31815	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GWQ54_RS31825	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GWQ54_RS31840	COG0463	Glycosyl transferase, family 2
GWQ54_RS31850	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GWQ54_RS31855	COG0438	transferase activity, transferring glycosyl groups
GWQ54_RS31875	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GWQ54_RS31880	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GWQ54_RS31885	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GWQ54_RS31890	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GWQ54_RS31895	COG1530	ribonuclease E activity
GWQ54_RS31935	COG0772	Belongs to the SEDS family
GWQ54_RS31940	COG0768	penicillin binding
GWQ54_RS31955	COG1077	Cell shape determining protein MreB Mrl
GWQ54_RS31960	COG0105	UTP biosynthetic process
GWQ54_RS31970	COG0285	dihydrofolate synthase activity
GWQ54_RS31975	COG1077	Cell shape determining protein MreB Mrl
GWQ54_RS31980	COG4585	Histidine kinase
GWQ54_RS31990	COG0525	valine-tRNA ligase activity
GWQ54_RS32000	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GWQ54_RS32005	COG0740	serine-type endopeptidase activity
GWQ54_RS32010	COG0740	serine-type endopeptidase activity
GWQ54_RS32015	COG0544	peptidyl-prolyl cis-trans isomerase activity
GWQ54_RS32045	COG1136	(ABC) transporter
GWQ54_RS32045	COG0577	efflux transmembrane transporter activity
GWQ54_RS32055	COG4552	Acetyltransferase involved in intracellular survival and related
GWQ54_RS32070	COG1113	amino acid transport
GWQ54_RS32080	COG1268	BioY protein
GWQ54_RS32085	COG1113	amino acid transport
GWQ54_RS32090	COG1113	amino acid transport
GWQ54_RS32095	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GWQ54_RS32105	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GWQ54_RS32130	COG2234	aminopeptidase activity
GWQ54_RS32160	COG4266	Belongs to the allantoicase family
GWQ54_RS32165	COG0667	Aldo Keto reductase
GWQ54_RS32180	COG0697	spore germination
GWQ54_RS32190	COG1846	Transcriptional regulator
GWQ54_RS32210	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GWQ54_RS32220	COG0668	transmembrane transport
GWQ54_RS32235	COG1940	carbohydrate kinase activity
GWQ54_RS32245	COG1175	transmembrane transport
GWQ54_RS32250	COG0395	ABC-type sugar transport system, permease component
GWQ54_RS32255	COG1486	melibiose metabolic process
GWQ54_RS32270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GWQ54_RS32300	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GWQ54_RS32320	COG1136	(ABC) transporter
GWQ54_RS32320	COG0577	efflux transmembrane transporter activity
GWQ54_RS32345	COG0629	single-stranded DNA binding
GWQ54_RS32365	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
GWQ54_RS32370	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GWQ54_RS32375	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GWQ54_RS32385	COG1131	(ABC) transporter
GWQ54_RS32420	COG3962	Belongs to the TPP enzyme family
GWQ54_RS32425	COG3718	enzyme involved in inositol metabolism
GWQ54_RS32465	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GWQ54_RS32485	COG1609	Transcriptional regulator
GWQ54_RS32490	COG0673	inositol 2-dehydrogenase activity
GWQ54_RS32525	COG0583	DNA-binding transcription factor activity
GWQ54_RS32545	COG1472	Belongs to the glycosyl hydrolase 3 family
GWQ54_RS32565	COG1132	(ABC) transporter
GWQ54_RS32570	COG0028	Belongs to the TPP enzyme family
GWQ54_RS32580	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GWQ54_RS32595	COG1946	Acyl-CoA thioesterase
GWQ54_RS32610	COG1309	transcriptional regulator
GWQ54_RS32615	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GWQ54_RS32630	COG1960	acyl-CoA dehydrogenase activity
GWQ54_RS32660	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GWQ54_RS32670	COG0589	response to stress
GWQ54_RS32680	COG4977	sequence-specific DNA binding
GWQ54_RS32685	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GWQ54_RS32720	COG2985	domain, Protein
GWQ54_RS32750	COG5002	protein histidine kinase activity
GWQ54_RS32755	COG0745	RESPONSE REGULATOR receiver
GWQ54_RS32765	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GWQ54_RS32780	COG0588	phosphoglycerate mutase activity
GWQ54_RS32835	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GWQ54_RS32840	COG0154	amidase activity
GWQ54_RS32845	COG4150	thiosulfate binding
GWQ54_RS32850	COG0765	amino acid transport
GWQ54_RS32855	COG0765	amino acid transport
GWQ54_RS32860	COG1126	abc transporter atp-binding protein
GWQ54_RS32875	COG0477	Major facilitator Superfamily
GWQ54_RS32885	COG0318	PFAM AMP-dependent synthetase and ligase
GWQ54_RS32890	COG3397	chitin binding
GWQ54_RS32955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GWQ54_RS32960	COG2188	Transcriptional regulator
GWQ54_RS32975	COG0673	inositol 2-dehydrogenase activity
GWQ54_RS32980	COG4702	Belongs to the UPF0303 family
GWQ54_RS32995	COG0706	membrane insertase activity
GWQ54_RS33015	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GWQ54_RS33025	COG3764	Sortase (surface protein transpeptidase)
GWQ54_RS33070	COG2733	membrane
GWQ54_RS33080	COG4555	ABC transporter
GWQ54_RS33095	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GWQ54_RS33135	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GWQ54_RS33145	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GWQ54_RS33150	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GWQ54_RS33155	COG1263	PTS System
GWQ54_RS33160	COG1263	PTS System
GWQ54_RS33165	COG1234	tRNA 3'-trailer cleavage
GWQ54_RS33185	COG1120	ATPase activity
GWQ54_RS33190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GWQ54_RS33205	COG1113	amino acid transport
GWQ54_RS33215	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GWQ54_RS33225	COG1335	isochorismatase
GWQ54_RS33265	COG0277	FAD linked oxidase domain protein
GWQ54_RS33275	COG3185	4-Hydroxyphenylpyruvate dioxygenase
GWQ54_RS33285	COG1174	glycine betaine transport
GWQ54_RS33295	COG1174	glycine betaine transport
GWQ54_RS33345	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GWQ54_RS33360	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GWQ54_RS33365	COG0395	ABC-type sugar transport system, permease component
GWQ54_RS33385	COG1678	Uncharacterized ACR, COG1678
GWQ54_RS33390	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GWQ54_RS33395	COG0776	regulation of translation
GWQ54_RS33405	COG3973	AAA domain
GWQ54_RS33440	COG2223	nitrite transmembrane transporter activity
GWQ54_RS33460	COG0583	DNA-binding transcription factor activity
GWQ54_RS33480	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GWQ54_RS33485	COG0793	Belongs to the peptidase S41A family
GWQ54_RS33495	COG2884	Cell division ATP-binding protein ftsE
GWQ54_RS33510	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GWQ54_RS33515	COG0515	serine threonine protein kinase
GWQ54_RS33520	COG0515	serine threonine protein kinase
GWQ54_RS33525	COG1674	ftsk spoiiie
GWQ54_RS33530	COG1653	transport
GWQ54_RS33535	COG1175	transmembrane transport
GWQ54_RS33540	COG0395	ABC-type sugar transport system, permease component
GWQ54_RS33545	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GWQ54_RS33550	COG1309	transcriptional regulator
GWQ54_RS33570	COG2902	Dehydrogenase
GWQ54_RS33595	COG0653	protein targeting
GWQ54_RS33605	COG3214	Protein conserved in bacteria
GWQ54_RS33610	COG2197	response regulator
GWQ54_RS33615	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GWQ54_RS33620	COG0823	Involved in the tonB-independent uptake of proteins
GWQ54_RS33625	COG5002	protein histidine kinase activity
GWQ54_RS33625	COG5000	phosphorelay sensor kinase activity
GWQ54_RS33630	COG0745	RESPONSE REGULATOR receiver
GWQ54_RS33635	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
GWQ54_RS33655	COG0714	Associated with various cellular activities
GWQ54_RS33695	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GWQ54_RS33700	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GWQ54_RS33700	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GWQ54_RS33700	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GWQ54_RS33710	COG1482	cell wall glycoprotein biosynthetic process
GWQ54_RS33720	COG2835	tetraacyldisaccharide 4'-kinase activity
GWQ54_RS33725	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GWQ54_RS33760	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GWQ54_RS33765	COG0778	Nitroreductase
GWQ54_RS33765	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
GWQ54_RS33800	COG1316	TRANSCRIPTIONal
GWQ54_RS33810	COG1316	TRANSCRIPTIONal
GWQ54_RS33815	COG1607	acyl-coa hydrolase
GWQ54_RS33820	COG1316	TRANSCRIPTIONal
GWQ54_RS33855	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GWQ54_RS33870	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GWQ54_RS33885	COG2205	protein histidine kinase activity
GWQ54_RS33890	COG0745	RESPONSE REGULATOR receiver
GWQ54_RS33895	COG3104	oligopeptide transport
GWQ54_RS33930	COG1366	Belongs to the anti-sigma-factor antagonist family
GWQ54_RS33935	COG1191	sigma factor activity
GWQ54_RS33980	COG1228	amidohydrolase
GWQ54_RS33990	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GWQ54_RS33995	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GWQ54_RS34040	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GWQ54_RS34055	COG2755	lipolytic protein G-D-S-L family
GWQ54_RS34060	COG0183	Belongs to the thiolase family
GWQ54_RS34100	COG1136	(ABC) transporter
GWQ54_RS34105	COG1136	(ABC) transporter
GWQ54_RS34105	COG0577	efflux transmembrane transporter activity
GWQ54_RS34110	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GWQ54_RS34135	COG0148	phosphopyruvate hydratase activity
GWQ54_RS34150	COG2124	cytochrome p450
GWQ54_RS34230	COG1595	DNA-templated transcription, initiation
GWQ54_RS34245	COG0577	efflux transmembrane transporter activity
GWQ54_RS34250	COG1136	(ABC) transporter
GWQ54_RS34255	COG0477	Major facilitator Superfamily
GWQ54_RS34285	COG4585	Histidine kinase
GWQ54_RS34300	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GWQ54_RS34305	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GWQ54_RS34315	COG0583	DNA-binding transcription factor activity
GWQ54_RS34320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GWQ54_RS34325	COG0193	aminoacyl-tRNA hydrolase activity
GWQ54_RS34335	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GWQ54_RS34345	COG1309	transcriptional regulator
GWQ54_RS34360	COG4106	trans-aconitate 2-methyltransferase activity
GWQ54_RS34365	COG1846	Transcriptional regulator
GWQ54_RS34370	COG2197	response regulator
GWQ54_RS34380	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GWQ54_RS34420	COG0488	(ABC) transporter
GWQ54_RS34430	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GWQ54_RS34435	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GWQ54_RS34445	COG0084	hydrolase, TatD family'
GWQ54_RS34475	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GWQ54_RS34480	COG1122	ATPase activity
GWQ54_RS34490	COG0310	cobalt ion transport
GWQ54_RS34500	COG2409	Drug exporters of the RND superfamily
GWQ54_RS34510	COG0793	Belongs to the peptidase S41A family
GWQ54_RS34510	COG4946	Tricorn protease homolog
GWQ54_RS34515	COG1028	Short-chain dehydrogenase reductase Sdr
GWQ54_RS34520	COG2267	carboxylic ester hydrolase activity
GWQ54_RS34525	COG2072	flavoprotein involved in K transport
GWQ54_RS34535	COG0708	Exodeoxyribonuclease III
GWQ54_RS34560	COG0315	cyclic pyranopterin monophosphate synthase activity
GWQ54_RS34560	COG0521	Mo-molybdopterin cofactor biosynthetic process
GWQ54_RS34565	COG0315	cyclic pyranopterin monophosphate synthase activity
GWQ54_RS34575	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GWQ54_RS34580	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GWQ54_RS34585	COG2366	antibiotic biosynthetic process
GWQ54_RS34590	COG3263	regulation of cellular component size
GWQ54_RS34605	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GWQ54_RS34615	COG1970	mechanosensitive ion channel activity
GWQ54_RS34635	COG0437	4 iron, 4 sulfur cluster binding
GWQ54_RS34640	COG0243	molybdopterin cofactor binding
GWQ54_RS34650	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GWQ54_RS34660	COG2223	nitrite transmembrane transporter activity
GWQ54_RS34665	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GWQ54_RS34665	COG2146	nitrite reductase [NAD(P)H] activity
GWQ54_RS34725	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GWQ54_RS34725	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GWQ54_RS34725	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GWQ54_RS34730	COG1105	Belongs to the carbohydrate kinase PfkB family
GWQ54_RS34735	COG1349	DNA-binding transcription factor activity
GWQ54_RS34740	COG0477	Major facilitator Superfamily
GWQ54_RS34755	COG1247	-acetyltransferase
GWQ54_RS34760	COG3384	dioxygenase
GWQ54_RS34765	COG1846	Transcriptional regulator
GWQ54_RS34795	COG1376	ErfK ybiS ycfS ynhG family protein
GWQ54_RS34805	COG0582	viral genome integration into host DNA
GWQ54_RS34895	COG0243	molybdopterin cofactor binding
GWQ54_RS34905	COG1686	Belongs to the peptidase S11 family
GWQ54_RS34955	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
GWQ54_RS35015	COG1131	(ABC) transporter
GWQ54_RS35085	COG1024	Enoyl-CoA hydratase
GWQ54_RS35110	COG2890	protein-(glutamine-N5) methyltransferase activity
GWQ54_RS35115	COG0515	serine threonine protein kinase
GWQ54_RS35115	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GWQ54_RS35135	COG1960	acyl-CoA dehydrogenase activity
GWQ54_RS35150	COG0259	pyridoxamine-phosphate oxidase activity
GWQ54_RS35165	COG2072	flavoprotein involved in K transport
GWQ54_RS35175	COG1024	Enoyl-CoA hydratase
GWQ54_RS35180	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GWQ54_RS35215	COG1960	acyl-CoA dehydrogenase activity
GWQ54_RS35220	COG1028	Short-chain dehydrogenase reductase Sdr
GWQ54_RS35235	COG1960	acyl-CoA dehydrogenase activity
GWQ54_RS35240	COG1960	acyl-CoA dehydrogenase activity
GWQ54_RS35250	COG0318	PFAM AMP-dependent synthetase and ligase
GWQ54_RS35255	COG0823	Involved in the tonB-independent uptake of proteins
GWQ54_RS35265	COG1366	Belongs to the anti-sigma-factor antagonist family
GWQ54_RS35320	COG2945	thiolester hydrolase activity
GWQ54_RS35320	COG0596	Alpha beta hydrolase
GWQ54_RS35330	COG4821	SIS domain
GWQ54_RS35345	COG0259	pyridoxamine-phosphate oxidase activity
GWQ54_RS35445	COG0438	transferase activity, transferring glycosyl groups
GWQ54_RS35450	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GWQ54_RS35460	COG0728	peptidoglycan biosynthetic process
GWQ54_RS35530	COG0318	PFAM AMP-dependent synthetase and ligase
GWQ54_RS35545	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GWQ54_RS35565	COG5006	permease, DMT superfamily
GWQ54_RS35605	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GWQ54_RS35635	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GWQ54_RS35650	COG2197	response regulator
GWQ54_RS35655	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GWQ54_RS35655	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GWQ54_RS35700	COG2723	6-phospho-beta-galactosidase activity
GWQ54_RS35735	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GWQ54_RS35740	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GWQ54_RS35740	COG1754	DNA topoisomerase type I activity
GWQ54_RS35750	COG2890	protein-(glutamine-N5) methyltransferase activity
GWQ54_RS35760	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
GWQ54_RS35765	COG2172	sigma factor antagonist activity
GWQ54_RS35770	COG1366	Belongs to the anti-sigma-factor antagonist family
GWQ54_RS35775	COG1111	helicase
GWQ54_RS35775	COG1205	dead DEAH box helicase
GWQ54_RS35835	COG0288	reversible hydration of carbon dioxide
GWQ54_RS35840	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GWQ54_RS35845	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GWQ54_RS35855	COG2267	carboxylic ester hydrolase activity
GWQ54_RS35860	COG1486	melibiose metabolic process
GWQ54_RS35890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GWQ54_RS35920	COG0003	Pfam Anion-transporting ATPase
GWQ54_RS35930	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GWQ54_RS35935	COG1610	YqeY-like protein
GWQ54_RS35940	COG1408	metallophosphoesterase
GWQ54_RS35965	COG1309	transcriptional regulator
GWQ54_RS35975	COG0596	Alpha beta hydrolase
GWQ54_RS35980	COG0300	oxidoreductase activity
GWQ54_RS35985	COG2814	Major facilitator Superfamily
GWQ54_RS36035	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
GWQ54_RS36065	COG2226	methyltransferase
GWQ54_RS36085	COG2197	response regulator
GWQ54_RS36090	COG0318	PFAM AMP-dependent synthetase and ligase
GWQ54_RS36095	COG0156	8-amino-7-oxononanoate synthase activity
GWQ54_RS36100	COG0318	PFAM AMP-dependent synthetase and ligase
GWQ54_RS36110	COG0745	RESPONSE REGULATOR receiver
GWQ54_RS36115	COG2205	protein histidine kinase activity
GWQ54_RS36120	COG1136	(ABC) transporter
GWQ54_RS36125	COG1136	(ABC) transporter
GWQ54_RS36125	COG0577	efflux transmembrane transporter activity
GWQ54_RS36155	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
GWQ54_RS36160	COG2814	Major facilitator Superfamily
GWQ54_RS36160	COG0477	Major facilitator Superfamily
GWQ54_RS36175	COG0512	Glutamine amidotransferase of anthranilate synthase
GWQ54_RS36205	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GWQ54_RS36215	COG3485	protocatechuate 3,4-dioxygenase
GWQ54_RS36230	COG1414	Transcriptional regulator
GWQ54_RS36255	COG1316	TRANSCRIPTIONal
GWQ54_RS36260	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GWQ54_RS36285	COG1595	DNA-templated transcription, initiation
GWQ54_RS36305	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GWQ54_RS36310	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GWQ54_RS36325	COG0463	Glycosyl transferase, family 2
GWQ54_RS36330	COG1802	Transcriptional regulator
GWQ54_RS36335	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GWQ54_RS36395	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GWQ54_RS36410	COG1131	(ABC) transporter
GWQ54_RS36415	COG3559	Exporter of polyketide antibiotics
GWQ54_RS36430	COG2197	response regulator
GWQ54_RS36435	COG4585	Histidine kinase
GWQ54_RS36460	COG3844	kynureninase activity
GWQ54_RS36480	COG0477	Major facilitator Superfamily
GWQ54_RS36485	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GWQ54_RS36490	COG0191	fructose-bisphosphate aldolase activity
GWQ54_RS36495	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GWQ54_RS36510	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GWQ54_RS36540	COG0542	response to heat
GWQ54_RS36570	COG0789	Transcriptional regulator
GWQ54_RS36575	COG0484	heat shock protein binding
GWQ54_RS36580	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GWQ54_RS36585	COG0443	Heat shock 70 kDa protein
GWQ54_RS36595	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GWQ54_RS36600	COG1088	dTDP-glucose 4,6-dehydratase activity
GWQ54_RS36605	COG0247	lactate metabolic process
GWQ54_RS36605	COG2181	nitrate reductase activity
GWQ54_RS36625	COG0717	Belongs to the dCTP deaminase family
GWQ54_RS36640	COG0596	Alpha beta hydrolase
GWQ54_RS36680	COG0330	HflC and HflK could
GWQ54_RS36725	COG1280	lysine exporter protein (LysE YggA)
GWQ54_RS36745	COG4948	Mandelate Racemase Muconate Lactonizing
GWQ54_RS36770	COG1278	Cold shock
GWQ54_RS36775	COG0513	Belongs to the DEAD box helicase family
GWQ54_RS36790	COG1802	Transcriptional regulator
GWQ54_RS36805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GWQ54_RS36810	COG2837	iron assimilation
GWQ54_RS36855	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
GWQ54_RS36890	COG1181	Belongs to the D-alanine--D-alanine ligase family
GWQ54_RS36895	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GWQ54_RS36905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GWQ54_RS36915	COG0069	glutamate synthase activity
GWQ54_RS36920	COG0017	Asparaginyl-tRNA synthetase
GWQ54_RS36945	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GWQ54_RS36970	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GWQ54_RS37600	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GWQ54_RS37630	COG2230	cyclopropane-fatty-acyl-phospholipid synthase