locus-tag	class	description
HUT14_RS00015	COG0515	serine threonine protein kinase
HUT14_RS00015	COG2815	serine threonine protein kinase
HUT14_RS00050	COG0789	Transcriptional regulator
HUT14_RS00170	COG2197	response regulator
HUT14_RS00175	COG4585	Histidine kinase
HUT14_RS00210	COG2226	methyltransferase
HUT14_RS00215	COG3708	Transcriptional regulator
HUT14_RS00215	COG2207	Transcriptional regulator
HUT14_RS00250	COG3647	Membrane
HUT14_RS00260	COG1595	DNA-templated transcription, initiation
HUT14_RS00270	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT14_RS00275	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HUT14_RS00300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUT14_RS00310	COG2223	nitrite transmembrane transporter activity
HUT14_RS00330	COG3507	Belongs to the glycosyl hydrolase 43 family
HUT14_RS00370	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT14_RS00420	COG3629	intracellular signal transduction
HUT14_RS00420	COG3903	Transcriptional regulator
HUT14_RS00435	COG0515	serine threonine protein kinase
HUT14_RS00515	COG4106	trans-aconitate 2-methyltransferase activity
HUT14_RS00525	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT14_RS00535	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT14_RS00545	COG3251	PFAM MbtH domain protein
HUT14_RS00555	COG3340	Belongs to the peptidase S51 family
HUT14_RS00565	COG2197	response regulator
HUT14_RS00590	COG2124	cytochrome p450
HUT14_RS00605	COG2409	Drug exporters of the RND superfamily
HUT14_RS00640	COG0477	Major facilitator Superfamily
HUT14_RS00660	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
HUT14_RS00675	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUT14_RS00680	COG1309	transcriptional regulator
HUT14_RS00710	COG1595	DNA-templated transcription, initiation
HUT14_RS00720	COG2814	Major facilitator Superfamily
HUT14_RS00725	COG1028	Short-chain dehydrogenase reductase Sdr
HUT14_RS00740	COG4977	sequence-specific DNA binding
HUT14_RS00795	COG0596	Alpha beta hydrolase
HUT14_RS00810	COG0110	maltose O-acetyltransferase activity
HUT14_RS00815	COG1280	lysine exporter protein (LysE YggA)
HUT14_RS00875	COG1366	Belongs to the anti-sigma-factor antagonist family
HUT14_RS00880	COG0783	Belongs to the Dps family
HUT14_RS00885	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
HUT14_RS00910	COG0741	lytic transglycosylase activity
HUT14_RS00910	COG0739	heme binding
HUT14_RS00910	COG1196	nuclear chromosome segregation
HUT14_RS00920	COG2267	carboxylic ester hydrolase activity
HUT14_RS00960	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
HUT14_RS00960	COG2308	Evidence 4 Homologs of previously reported genes of
HUT14_RS00965	COG0367	asparagine synthase
HUT14_RS00985	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HUT14_RS00990	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HUT14_RS01015	COG0488	(ABC) transporter
HUT14_RS01040	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HUT14_RS01045	COG3119	arylsulfatase activity
HUT14_RS01095	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUT14_RS01095	COG1263	PTS System
HUT14_RS01100	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUT14_RS01100	COG1017	nitric oxide dioxygenase activity
HUT14_RS01115	COG1140	nitrate reductase beta subunit
HUT14_RS01125	COG2181	nitrate reductase activity
HUT14_RS01160	COG1024	Enoyl-CoA hydratase
HUT14_RS01170	COG2318	DinB family
HUT14_RS01195	COG4109	DRTGG domain
HUT14_RS01210	COG1269	ATP hydrolysis coupled proton transport
HUT14_RS01230	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
HUT14_RS01235	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
HUT14_RS01250	COG0516	GMP reductase activity
HUT14_RS01250	COG0517	IMP dehydrogenase activity
HUT14_RS01270	COG1357	PFAM Pentapeptide repeats (8 copies)
HUT14_RS01275	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HUT14_RS01280	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HUT14_RS01325	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
HUT14_RS01355	COG0375	protein maturation
HUT14_RS01360	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HUT14_RS01365	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
HUT14_RS01375	COG0409	Hydrogenase expression formation protein
HUT14_RS01450	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
HUT14_RS01460	COG1597	lipid kinase activity
HUT14_RS01465	COG0277	FAD linked oxidase domain protein
HUT14_RS01520	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HUT14_RS01525	COG0395	ABC-type sugar transport system, permease component
HUT14_RS01530	COG1175	transmembrane transport
HUT14_RS01550	COG0438	transferase activity, transferring glycosyl groups
HUT14_RS01580	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HUT14_RS01670	COG1609	Transcriptional regulator
HUT14_RS01680	COG1129	ABC transporter
HUT14_RS01685	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUT14_RS01690	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUT14_RS01720	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HUT14_RS01745	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUT14_RS01770	COG2124	cytochrome p450
HUT14_RS01780	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HUT14_RS01790	COG4941	Belongs to the sigma-70 factor family
HUT14_RS01795	COG3795	YCII-related domain
HUT14_RS01800	COG1309	transcriptional regulator
HUT14_RS01805	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HUT14_RS01815	COG0183	Belongs to the thiolase family
HUT14_RS01820	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT14_RS01840	COG1414	Transcriptional regulator
HUT14_RS01865	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HUT14_RS01880	COG2259	Doxx family
HUT14_RS01925	COG0395	ABC-type sugar transport system, permease component
HUT14_RS01930	COG1175	transmembrane transport
HUT14_RS01935	COG1653	transport
HUT14_RS01940	COG1501	Belongs to the glycosyl hydrolase 31 family
HUT14_RS01945	COG2326	polyphosphate kinase activity
HUT14_RS01950	COG1028	Short-chain dehydrogenase reductase Sdr
HUT14_RS01965	COG4209	transmembrane transport
HUT14_RS01970	COG0395	ABC-type sugar transport system, permease component
HUT14_RS01990	COG0110	maltose O-acetyltransferase activity
HUT14_RS02000	COG0714	Associated with various cellular activities
HUT14_RS02015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT14_RS02025	COG1120	ATPase activity
HUT14_RS02045	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HUT14_RS02055	COG3290	protein histidine kinase activity
HUT14_RS02065	COG0326	Molecular chaperone. Has ATPase activity
HUT14_RS02090	COG0667	Aldo Keto reductase
HUT14_RS02110	COG0559	Belongs to the binding-protein-dependent transport system permease family
HUT14_RS02120	COG0410	ABC transporter
HUT14_RS02125	COG2508	Transcriptional regulator
HUT14_RS02160	COG0243	molybdopterin cofactor binding
HUT14_RS02190	COG3290	protein histidine kinase activity
HUT14_RS02215	COG1017	nitric oxide dioxygenase activity
HUT14_RS02215	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUT14_RS02275	COG4977	sequence-specific DNA binding
HUT14_RS02285	COG1132	(ABC) transporter
HUT14_RS02290	COG0667	Aldo Keto reductase
HUT14_RS02300	COG0673	inositol 2-dehydrogenase activity
HUT14_RS02325	COG1554	hydrolase, family 65, central catalytic
HUT14_RS02375	COG1309	transcriptional regulator
HUT14_RS02395	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HUT14_RS02415	COG1028	Short-chain dehydrogenase reductase Sdr
HUT14_RS02435	COG1132	(ABC) transporter
HUT14_RS02520	COG0248	Ppx GppA phosphatase
HUT14_RS02535	COG2890	protein-(glutamine-N5) methyltransferase activity
HUT14_RS02595	COG0667	Aldo Keto reductase
HUT14_RS02615	COG0435	Glutathione S-transferase
HUT14_RS02650	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
HUT14_RS02650	COG1796	DNA polymerase
HUT14_RS02665	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HUT14_RS02695	COG2706	6-phosphogluconolactonase activity
HUT14_RS02705	COG1309	transcriptional regulator
HUT14_RS02715	COG1595	DNA-templated transcription, initiation
HUT14_RS02730	COG1609	Transcriptional regulator
HUT14_RS02750	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUT14_RS02755	COG1129	ABC transporter
HUT14_RS02760	COG4952	isomerase
HUT14_RS02765	COG3347	Dehydrogenase
HUT14_RS02765	COG1028	Short-chain dehydrogenase reductase Sdr
HUT14_RS02770	COG1070	Carbohydrate kinase
HUT14_RS02775	COG0247	lactate metabolic process
HUT14_RS02780	COG1139	Iron-sulfur cluster binding protein
HUT14_RS02785	COG1556	Lactate utilization protein
HUT14_RS02790	COG1136	(ABC) transporter
HUT14_RS02790	COG0577	efflux transmembrane transporter activity
HUT14_RS02800	COG0542	response to heat
HUT14_RS02855	COG0242	peptide deformylase activity
HUT14_RS02865	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HUT14_RS02870	COG1609	Transcriptional regulator
HUT14_RS02890	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HUT14_RS02895	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HUT14_RS02900	COG2080	2 iron, 2 sulfur cluster binding
HUT14_RS02910	COG0583	DNA-binding transcription factor activity
HUT14_RS02920	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUT14_RS02935	COG1881	PFAM PEBP family protein
HUT14_RS02955	COG1335	isochorismatase
HUT14_RS02985	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HUT14_RS02990	COG0121	glutamine amidotransferase
HUT14_RS02995	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
HUT14_RS03000	COG2182	Extracellular solute-binding protein
HUT14_RS03005	COG3360	Dodecin
HUT14_RS03015	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
HUT14_RS03030	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HUT14_RS03035	COG1053	succinate dehydrogenase
HUT14_RS03045	COG0583	DNA-binding transcription factor activity
HUT14_RS03055	COG0726	polysaccharide deacetylase
HUT14_RS03120	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HUT14_RS03165	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HUT14_RS03170	COG0297	glycogen (starch) synthase activity
HUT14_RS03190	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HUT14_RS03205	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HUT14_RS03225	COG2382	esterase
HUT14_RS03225	COG3507	Belongs to the glycosyl hydrolase 43 family
HUT14_RS03225	COG3693	PFAM glycoside hydrolase, family 10
HUT14_RS03235	COG3693	PFAM glycoside hydrolase, family 10
HUT14_RS03260	COG0179	Fumarylacetoacetate (FAA) hydrolase
HUT14_RS03265	COG4948	Mandelate Racemase Muconate Lactonizing
HUT14_RS03290	COG0247	lactate metabolic process
HUT14_RS03290	COG0277	FAD linked oxidase domain protein
HUT14_RS03295	COG0028	Belongs to the TPP enzyme family
HUT14_RS03300	COG4948	Mandelate Racemase Muconate Lactonizing
HUT14_RS03310	COG0300	oxidoreductase activity
HUT14_RS03325	COG0513	Belongs to the DEAD box helicase family
HUT14_RS03330	COG1132	(ABC) transporter
HUT14_RS03335	COG2860	membrane
HUT14_RS03340	COG1473	amidohydrolase
HUT14_RS03345	COG1595	DNA-templated transcription, initiation
HUT14_RS03380	COG1874	Beta-galactosidase
HUT14_RS03380	COG0366	Alpha amylase catalytic
HUT14_RS03390	COG1472	Belongs to the glycosyl hydrolase 3 family
HUT14_RS03400	COG1175	transmembrane transport
HUT14_RS03405	COG1653	transport
HUT14_RS03420	COG0395	ABC-type sugar transport system, permease component
HUT14_RS03485	COG4585	Histidine kinase
HUT14_RS03490	COG2197	response regulator
HUT14_RS03500	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HUT14_RS03505	COG1132	(ABC) transporter
HUT14_RS03515	COG0668	transmembrane transport
HUT14_RS03520	COG2838	Isocitrate dehydrogenase
HUT14_RS03565	COG2814	Major facilitator Superfamily
HUT14_RS03580	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HUT14_RS03585	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HUT14_RS03590	COG2188	Transcriptional regulator
HUT14_RS03595	COG0673	inositol 2-dehydrogenase activity
HUT14_RS03600	COG1609	Transcriptional regulator
HUT14_RS03610	COG1028	Short-chain dehydrogenase reductase Sdr
HUT14_RS03615	COG0673	inositol 2-dehydrogenase activity
HUT14_RS03620	COG0673	inositol 2-dehydrogenase activity
HUT14_RS03625	COG1312	Catalyzes the dehydration of D-mannonate
HUT14_RS03645	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUT14_RS03655	COG3718	enzyme involved in inositol metabolism
HUT14_RS03660	COG3962	Belongs to the TPP enzyme family
HUT14_RS03665	COG2188	Transcriptional regulator
HUT14_RS03710	COG0183	Belongs to the thiolase family
HUT14_RS03765	COG3959	Transketolase, thiamine diphosphate binding domain
HUT14_RS03770	COG3958	Transketolase
HUT14_RS03795	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HUT14_RS03795	COG2010	Cytochrome c
HUT14_RS03805	COG0191	fructose-bisphosphate aldolase activity
HUT14_RS03815	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HUT14_RS03820	COG0395	ABC-type sugar transport system, permease component
HUT14_RS03835	COG1349	DNA-binding transcription factor activity
HUT14_RS03845	COG0673	inositol 2-dehydrogenase activity
HUT14_RS03860	COG1028	Short-chain dehydrogenase reductase Sdr
HUT14_RS03885	COG1215	transferase activity, transferring glycosyl groups
HUT14_RS03915	COG1349	DNA-binding transcription factor activity
HUT14_RS03945	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
HUT14_RS03950	COG1940	carbohydrate kinase activity
HUT14_RS03960	COG2813	Specifically methylates the guanine in position
HUT14_RS03975	COG3387	PFAM Glycoside hydrolase 15-related
HUT14_RS04000	COG0673	inositol 2-dehydrogenase activity
HUT14_RS04050	COG2197	response regulator
HUT14_RS04055	COG4585	Histidine kinase
HUT14_RS04070	COG1660	Displays ATPase and GTPase activities
HUT14_RS04105	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HUT14_RS04155	COG0584	glycerophosphoryl diester phosphodiesterase
HUT14_RS04190	COG0671	phosphoesterase, PA-phosphatase related
HUT14_RS04195	COG1309	transcriptional regulator
HUT14_RS04220	COG0640	Transcriptional regulator
HUT14_RS04225	COG1902	pentaerythritol trinitrate reductase activity
HUT14_RS04240	COG1960	acyl-CoA dehydrogenase activity
HUT14_RS04250	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HUT14_RS04275	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUT14_RS04320	COG0589	response to stress
HUT14_RS04340	COG2205	protein histidine kinase activity
HUT14_RS04340	COG0784	Response regulator, receiver
HUT14_RS04340	COG2198	Histidine kinase
HUT14_RS04365	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HUT14_RS04390	COG0432	Pfam Uncharacterised protein family UPF0047
HUT14_RS04395	COG2072	flavoprotein involved in K transport
HUT14_RS04400	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HUT14_RS04405	COG1132	(ABC) transporter
HUT14_RS04415	COG1132	(ABC) transporter
HUT14_RS04420	COG1132	(ABC) transporter
HUT14_RS04430	COG0254	rRNA binding
HUT14_RS04445	COG1946	Acyl-CoA thioesterase
HUT14_RS04455	COG2018	Roadblock/LC7 domain
HUT14_RS04495	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HUT14_RS04540	COG1960	acyl-CoA dehydrogenase activity
HUT14_RS04545	COG1960	acyl-CoA dehydrogenase activity
HUT14_RS04565	COG1793	dna ligase
HUT14_RS04575	COG1012	belongs to the aldehyde dehydrogenase family
HUT14_RS04590	COG1960	acyl-CoA dehydrogenase activity
HUT14_RS04600	COG0242	peptide deformylase activity
HUT14_RS04605	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HUT14_RS04610	COG3442	glutamine amidotransferase
HUT14_RS04615	COG0205	6-phosphofructokinase activity
HUT14_RS04635	COG3275	phosphorelay sensor kinase activity
HUT14_RS04640	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUT14_RS04655	COG1522	sequence-specific DNA binding
HUT14_RS04660	COG1834	amidinotransferase
HUT14_RS04665	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HUT14_RS04685	COG0204	Acyl-transferase
HUT14_RS04695	COG0829	nickel cation binding
HUT14_RS04700	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HUT14_RS04710	COG0804	urea catabolic process
HUT14_RS04715	COG0832	Belongs to the urease beta subunit family
HUT14_RS04720	COG0831	urea catabolic process
HUT14_RS04730	COG0740	serine-type endopeptidase activity
HUT14_RS04765	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HUT14_RS04770	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HUT14_RS04775	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HUT14_RS04780	COG2226	methyltransferase
HUT14_RS04795	COG1136	(ABC) transporter
HUT14_RS04795	COG0577	efflux transmembrane transporter activity
HUT14_RS04800	COG0456	acetyltransferase
HUT14_RS04820	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HUT14_RS04845	COG4585	Histidine kinase
HUT14_RS04850	COG2197	response regulator
HUT14_RS04855	COG1940	carbohydrate kinase activity
HUT14_RS04860	COG2188	Transcriptional regulator
HUT14_RS04865	COG1595	DNA-templated transcription, initiation
HUT14_RS04875	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT14_RS04890	COG0626	cystathionine gamma-synthase activity
HUT14_RS04915	COG0419	ATPase involved in DNA repair
HUT14_RS04920	COG0420	3'-5' exonuclease activity
HUT14_RS04925	COG1739	Uncharacterized protein family UPF0029
HUT14_RS04935	COG0215	cysteine-tRNA ligase activity
HUT14_RS04940	COG1832	CoA-binding protein
HUT14_RS04945	COG0640	Transcriptional regulator
HUT14_RS04970	COG0110	maltose O-acetyltransferase activity
HUT14_RS05005	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HUT14_RS05020	COG1968	undecaprenyl-diphosphatase activity
HUT14_RS05030	COG1028	Short-chain dehydrogenase reductase Sdr
HUT14_RS05045	COG0815	Transfers the fatty acyl group on membrane lipoproteins
HUT14_RS05055	COG2318	DinB family
HUT14_RS05070	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HUT14_RS05135	COG0697	spore germination
HUT14_RS05195	COG1733	regulation of RNA biosynthetic process
HUT14_RS05210	COG0725	ABC transporter, periplasmic molybdate-binding protein
HUT14_RS05225	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HUT14_RS05225	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HUT14_RS05235	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HUT14_RS05255	COG1716	ATPase activity
HUT14_RS05275	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HUT14_RS05305	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HUT14_RS05315	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUT14_RS05330	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HUT14_RS05350	COG2018	Roadblock/LC7 domain
HUT14_RS05390	COG2814	Major facilitator Superfamily
HUT14_RS05395	COG4336	lyase activity
HUT14_RS05400	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
HUT14_RS05405	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HUT14_RS05410	COG1984	allophanate hydrolase subunit 2
HUT14_RS05420	COG0438	transferase activity, transferring glycosyl groups
HUT14_RS05425	COG0438	transferase activity, transferring glycosyl groups
HUT14_RS05455	COG2364	Membrane
HUT14_RS05465	COG2270	Major facilitator Superfamily
HUT14_RS05475	COG3030	protein affecting phage T7 exclusion by the F plasmid
HUT14_RS05480	COG0463	Glycosyl transferase, family 2
HUT14_RS05505	COG1960	acyl-CoA dehydrogenase activity
HUT14_RS05555	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
HUT14_RS05560	COG0140	phosphoribosyl-ATP diphosphatase activity
HUT14_RS05565	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
HUT14_RS05570	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUT14_RS05570	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUT14_RS05575	COG3201	nicotinamide mononucleotide transporter
HUT14_RS05585	COG1090	epimerase
HUT14_RS05590	COG1846	Transcriptional regulator
HUT14_RS05590	COG1940	carbohydrate kinase activity
HUT14_RS05595	COG2223	nitrite transmembrane transporter activity
HUT14_RS05605	COG2233	PERMEase
HUT14_RS05625	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HUT14_RS05640	COG0531	amino acid
HUT14_RS05655	COG2390	Transcriptional regulator
HUT14_RS05660	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HUT14_RS05665	COG2409	Drug exporters of the RND superfamily
HUT14_RS05675	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HUT14_RS05690	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HUT14_RS05700	COG1758	RNA polymerase activity
HUT14_RS05705	COG0194	GDP metabolic process
HUT14_RS05715	COG0284	orotidine-5'-phosphate decarboxylase activity
HUT14_RS05720	COG0167	dihydroorotate dehydrogenase activity
HUT14_RS05725	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HUT14_RS05730	COG0505	Belongs to the CarA family
HUT14_RS05740	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HUT14_RS05745	COG0540	Belongs to the ATCase OTCase family
HUT14_RS05750	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HUT14_RS05760	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HUT14_RS05765	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HUT14_RS05770	COG0006	proline dipeptidase activity
HUT14_RS05780	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HUT14_RS05785	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HUT14_RS05790	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HUT14_RS05800	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HUT14_RS05810	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HUT14_RS05815	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HUT14_RS05830	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HUT14_RS05845	COG0124	histidyl-tRNA synthetase
HUT14_RS05855	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HUT14_RS05860	COG1196	nuclear chromosome segregation
HUT14_RS05865	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HUT14_RS05870	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HUT14_RS05875	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HUT14_RS05880	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HUT14_RS05890	COG2255	four-way junction helicase activity
HUT14_RS05895	COG0632	four-way junction helicase activity
HUT14_RS05900	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HUT14_RS05905	COG0217	transcriptional regulatory protein
HUT14_RS05910	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HUT14_RS05915	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HUT14_RS05925	COG0438	transferase activity, transferring glycosyl groups
HUT14_RS05930	COG1560	Kdo2-lipid A biosynthetic process
HUT14_RS05935	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HUT14_RS05955	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HUT14_RS05970	COG5002	protein histidine kinase activity
HUT14_RS05970	COG2176	DNA-directed DNA polymerase activity
HUT14_RS05995	COG0395	ABC-type sugar transport system, permease component
HUT14_RS06000	COG1175	transmembrane transport
HUT14_RS06055	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HUT14_RS06115	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HUT14_RS06120	COG0475	glutathione-regulated potassium exporter activity
HUT14_RS06125	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HUT14_RS06155	COG1960	acyl-CoA dehydrogenase activity
HUT14_RS06170	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT14_RS06205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT14_RS06230	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HUT14_RS06230	COG1648	precorrin-2 dehydrogenase activity
HUT14_RS06235	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
HUT14_RS06250	COG1464	Belongs to the NlpA lipoprotein family
HUT14_RS06255	COG2011	ABC-type metal ion transport system permease component
HUT14_RS06260	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HUT14_RS06290	COG0584	glycerophosphoryl diester phosphodiesterase
HUT14_RS06295	COG0318	PFAM AMP-dependent synthetase and ligase
HUT14_RS06295	COG0204	Acyl-transferase
HUT14_RS06300	COG0477	Major facilitator Superfamily
HUT14_RS06315	COG0165	Argininosuccinate lyase
HUT14_RS06320	COG0137	argininosuccinate synthase activity
HUT14_RS06355	COG1438	arginine binding
HUT14_RS06360	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HUT14_RS06365	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HUT14_RS06370	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HUT14_RS06375	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HUT14_RS06385	COG2259	Doxx family
HUT14_RS06415	COG0697	spore germination
HUT14_RS06425	COG1649	PFAM Uncharacterised BCR, COG1649
HUT14_RS06450	COG0072	phenylalanine-tRNA ligase activity
HUT14_RS06450	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HUT14_RS06455	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HUT14_RS06460	COG5002	protein histidine kinase activity
HUT14_RS06465	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUT14_RS06470	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HUT14_RS06475	COG0291	Belongs to the bacterial ribosomal protein bL35 family
HUT14_RS06480	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HUT14_RS06525	COG1012	belongs to the aldehyde dehydrogenase family
HUT14_RS06530	COG0174	glutamine synthetase
HUT14_RS06540	COG0531	amino acid
HUT14_RS06545	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HUT14_RS06560	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HUT14_RS06570	COG4176	ABC-type proline glycine betaine transport system permease component
HUT14_RS06575	COG4175	Glycine betaine
HUT14_RS06575	COG0517	IMP dehydrogenase activity
HUT14_RS06580	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HUT14_RS06595	COG0564	pseudouridine synthase activity
HUT14_RS06635	COG0805	protein transport
HUT14_RS06640	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HUT14_RS06660	COG2378	regulation of single-species biofilm formation
HUT14_RS06670	COG0545	Peptidyl-prolyl cis-trans isomerase
HUT14_RS06675	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
HUT14_RS06685	COG1609	Transcriptional regulator
HUT14_RS06690	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
HUT14_RS06695	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
HUT14_RS06710	COG4122	O-methyltransferase activity
HUT14_RS06715	COG1222	aaa ATPase
HUT14_RS06735	COG1994	Peptidase M50
HUT14_RS06735	COG0517	IMP dehydrogenase activity
HUT14_RS06745	COG2197	response regulator
HUT14_RS06750	COG4166	transmembrane transport
HUT14_RS06755	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUT14_RS06760	COG0646	methionine synthase
HUT14_RS06760	COG1410	methionine synthase
HUT14_RS06765	COG1414	Transcriptional regulator
HUT14_RS06770	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HUT14_RS06775	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HUT14_RS06780	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HUT14_RS06785	COG2186	Transcriptional regulator
HUT14_RS06795	COG0215	cysteine-tRNA ligase activity
HUT14_RS06810	COG0588	phosphoglycerate mutase activity
HUT14_RS06815	COG0598	Magnesium transport protein CorA
HUT14_RS06825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT14_RS06830	COG0667	Aldo Keto reductase
HUT14_RS06860	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUT14_RS06870	COG3012	SEC-C Motif Domain Protein
HUT14_RS06875	COG2186	Transcriptional regulator
HUT14_RS06880	COG3265	gluconokinase activity
HUT14_RS06910	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
HUT14_RS06915	COG2149	membrane
HUT14_RS06935	COG1960	acyl-CoA dehydrogenase activity
HUT14_RS06960	COG3876	Protein conserved in bacteria
HUT14_RS06990	COG1960	acyl-CoA dehydrogenase activity
HUT14_RS07000	COG0640	Transcriptional regulator
HUT14_RS07025	COG2851	Citrate transporter
HUT14_RS07030	COG0243	molybdopterin cofactor binding
HUT14_RS07035	COG1309	transcriptional regulator
HUT14_RS07045	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
HUT14_RS07050	COG2188	Transcriptional regulator
HUT14_RS07085	COG1595	DNA-templated transcription, initiation
HUT14_RS07110	COG2755	lipolytic protein G-D-S-L family
HUT14_RS07125	COG1649	PFAM Uncharacterised BCR, COG1649
HUT14_RS07125	COG0726	polysaccharide deacetylase
HUT14_RS07140	COG1725	Transcriptional regulator
HUT14_RS07185	COG0587	DNA-directed DNA polymerase activity
HUT14_RS07210	COG1799	cell septum assembly
HUT14_RS07215	COG1960	acyl-CoA dehydrogenase activity
HUT14_RS07220	COG0477	Major facilitator Superfamily
HUT14_RS07230	COG0671	phosphoesterase, PA-phosphatase related
HUT14_RS07260	COG1160	GTP binding
HUT14_RS07270	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
HUT14_RS07300	COG1187	pseudouridine synthase activity
HUT14_RS07305	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HUT14_RS07310	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HUT14_RS07325	COG0686	Belongs to the AlaDH PNT family
HUT14_RS07335	COG0494	nUDIX hydrolase
HUT14_RS07340	COG0504	CTP synthase activity
HUT14_RS07345	COG3387	PFAM Glycoside hydrolase 15-related
HUT14_RS07360	COG0497	DNA recombination
HUT14_RS07365	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HUT14_RS07385	COG1120	ATPase activity
HUT14_RS07390	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT14_RS07395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT14_RS07400	COG0647	UMP catabolic process
HUT14_RS07430	COG2094	Belongs to the DNA glycosylase MPG family
HUT14_RS07440	COG1881	PFAM PEBP family protein
HUT14_RS07460	COG1119	ATPase activity
HUT14_RS07475	COG2197	response regulator
HUT14_RS07485	COG4221	oxidoreductase activity
HUT14_RS07490	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HUT14_RS07500	COG0842	Transport permease protein
HUT14_RS07500	COG1131	(ABC) transporter
HUT14_RS07500	COG1716	ATPase activity
HUT14_RS07510	COG3830	Belongs to the UPF0237 family
HUT14_RS07510	COG0560	Phosphoserine phosphatase
HUT14_RS07515	COG0588	phosphoglycerate mutase activity
HUT14_RS07530	COG2186	Transcriptional regulator
HUT14_RS07540	COG1028	Short-chain dehydrogenase reductase Sdr
HUT14_RS07545	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
HUT14_RS07565	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HUT14_RS07585	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HUT14_RS07590	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUT14_RS07610	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUT14_RS07620	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HUT14_RS07650	COG3387	PFAM Glycoside hydrolase 15-related
HUT14_RS07690	COG1024	Enoyl-CoA hydratase
HUT14_RS07700	COG0488	(ABC) transporter
HUT14_RS07720	COG0235	Class ii aldolase
HUT14_RS07735	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HUT14_RS07740	COG1492	cobalamin metabolic process
HUT14_RS07760	COG1797	cobyrinic acid a,c-diamide synthase activity
HUT14_RS07820	COG0765	amino acid transport
HUT14_RS07830	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HUT14_RS07835	COG0456	acetyltransferase
HUT14_RS07840	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HUT14_RS07845	COG1917	Cupin 2, conserved barrel domain protein
HUT14_RS07850	COG5285	phytanoyl-CoA dioxygenase
HUT14_RS07855	COG3844	kynureninase activity
HUT14_RS07875	COG4585	Histidine kinase
HUT14_RS07880	COG2197	response regulator
HUT14_RS07890	COG1414	Transcriptional regulator
HUT14_RS07900	COG0768	penicillin binding
HUT14_RS07905	COG1595	DNA-templated transcription, initiation
HUT14_RS07920	COG3507	Belongs to the glycosyl hydrolase 43 family
HUT14_RS07930	COG4677	pectinesterase activity
HUT14_RS07935	COG3866	Pectate lyase
HUT14_RS07940	COG2755	lipolytic protein G-D-S-L family
HUT14_RS07950	COG3507	Belongs to the glycosyl hydrolase 43 family
HUT14_RS07965	COG0395	ABC-type sugar transport system, permease component
HUT14_RS07980	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUT14_RS07985	COG1802	Transcriptional regulator
HUT14_RS08005	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUT14_RS08010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUT14_RS08015	COG1349	DNA-binding transcription factor activity
HUT14_RS08030	COG0395	ABC-type sugar transport system, permease component
HUT14_RS08035	COG1063	alcohol dehydrogenase
HUT14_RS08080	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUT14_RS08090	COG1595	DNA-templated transcription, initiation
HUT14_RS08095	COG2171	N-acyltransferase activity
HUT14_RS08105	COG2151	metal-sulfur cluster biosynthetic enzyme
HUT14_RS08110	COG0822	iron-sulfur transferase activity
HUT14_RS08115	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HUT14_RS08120	COG0396	ATPase activity
HUT14_RS08130	COG0719	Fe-S assembly protein
HUT14_RS08145	COG1131	(ABC) transporter
HUT14_RS08155	COG1612	heme a metabolic process
HUT14_RS08175	COG0109	protoheme IX farnesyltransferase activity
HUT14_RS08185	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HUT14_RS08200	COG0363	glucosamine-6-phosphate deaminase activity
HUT14_RS08205	COG0395	ABC-type sugar transport system, permease component
HUT14_RS08210	COG1175	transmembrane transport
HUT14_RS08220	COG0366	Alpha amylase catalytic
HUT14_RS08225	COG1653	transport
HUT14_RS08230	COG1695	Transcriptional regulator
HUT14_RS08235	COG1136	(ABC) transporter
HUT14_RS08235	COG0577	efflux transmembrane transporter activity
HUT14_RS08250	COG0166	Belongs to the GPI family
HUT14_RS08260	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HUT14_RS08265	COG0149	triose-phosphate isomerase activity
HUT14_RS08270	COG0126	phosphoglycerate kinase activity
HUT14_RS08275	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HUT14_RS08285	COG1481	regulation of sporulation
HUT14_RS08290	COG0391	Required for morphogenesis under gluconeogenic growth conditions
HUT14_RS08295	COG1660	Displays ATPase and GTPase activities
HUT14_RS08300	COG0322	excinuclease ABC activity
HUT14_RS08315	COG0723	plastoquinol--plastocyanin reductase activity
HUT14_RS08320	COG1609	Transcriptional regulator
HUT14_RS08325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUT14_RS08330	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HUT14_RS08340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUT14_RS08345	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
HUT14_RS08350	COG0387	Pfam Sodium calcium exchanger
HUT14_RS08370	COG0556	nucleotide-excision repair
HUT14_RS08380	COG0584	glycerophosphoryl diester phosphodiesterase
HUT14_RS08385	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HUT14_RS08395	COG2313	pseudouridylate synthase activity
HUT14_RS08525	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HUT14_RS08530	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HUT14_RS08535	COG2267	carboxylic ester hydrolase activity
HUT14_RS08545	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HUT14_RS08550	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HUT14_RS08565	COG0237	dephospho-CoA kinase activity
HUT14_RS08575	COG0539	negative regulation of cytoplasmic translation
HUT14_RS08585	COG1643	Atp-dependent helicase
HUT14_RS08615	COG2050	protein possibly involved in aromatic compounds catabolism
HUT14_RS08640	COG0411	ABC transporter
HUT14_RS08670	COG0737	Belongs to the 5'-nucleotidase family
HUT14_RS08675	COG3486	L-lysine 6-monooxygenase (NADPH) activity
HUT14_RS08685	COG0745	RESPONSE REGULATOR receiver
HUT14_RS08690	COG0287	Prephenate dehydrogenase
HUT14_RS08690	COG1605	Chorismate mutase
HUT14_RS08700	COG2304	oxidoreductase activity
HUT14_RS08720	COG0067	glutamate synthase
HUT14_RS08720	COG0069	glutamate synthase activity
HUT14_RS08720	COG0070	glutamate synthase
HUT14_RS08730	COG1397	ADP-ribosylglycohydrolase
HUT14_RS08750	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUT14_RS08755	COG2301	Belongs to the HpcH HpaI aldolase family
HUT14_RS08760	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HUT14_RS08770	COG0159	tryptophan synthase activity
HUT14_RS08775	COG0133	tryptophan synthase activity
HUT14_RS08780	COG0134	indole-3-glycerol-phosphate synthase activity
HUT14_RS08800	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HUT14_RS08805	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HUT14_RS08820	COG0107	imidazoleglycerol-phosphate synthase activity
HUT14_RS08825	COG0251	oxidation-reduction process
HUT14_RS08830	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HUT14_RS08835	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HUT14_RS08845	COG0131	Imidazoleglycerol-phosphate dehydratase
HUT14_RS08850	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HUT14_RS08855	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HUT14_RS08880	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HUT14_RS08900	COG1432	Conserved Protein
HUT14_RS08910	COG0587	DNA-directed DNA polymerase activity
HUT14_RS08970	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HUT14_RS08980	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HUT14_RS08985	COG3599	regulation of cell shape
HUT14_RS08995	COG1799	cell septum assembly
HUT14_RS09010	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HUT14_RS09015	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HUT14_RS09020	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HUT14_RS09030	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HUT14_RS09035	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HUT14_RS09045	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HUT14_RS09060	COG0275	rRNA processing
HUT14_RS09070	COG0714	Associated with various cellular activities
HUT14_RS09100	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HUT14_RS09105	COG1511	domain protein
HUT14_RS09110	COG1309	transcriptional regulator
HUT14_RS09130	COG0352	thiamine-phosphate diphosphorylase activity
HUT14_RS09150	COG2022	thiamine diphosphate biosynthetic process
HUT14_RS09150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUT14_RS09160	COG2022	thiamine diphosphate biosynthetic process
HUT14_RS09165	COG2815	serine threonine protein kinase
HUT14_RS09165	COG0515	serine threonine protein kinase
HUT14_RS09170	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HUT14_RS09175	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HUT14_RS09180	COG2193	ferroxidase activity
HUT14_RS09190	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
HUT14_RS09205	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HUT14_RS09215	COG4585	Histidine kinase
HUT14_RS09240	COG1940	carbohydrate kinase activity
HUT14_RS09250	COG0003	Pfam Anion-transporting ATPase
HUT14_RS09270	COG0438	transferase activity, transferring glycosyl groups
HUT14_RS09290	COG1388	LysM domain
HUT14_RS09290	COG3103	Sh3 type 3 domain protein
HUT14_RS09290	COG0791	NLP P60 protein
HUT14_RS09315	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HUT14_RS09320	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HUT14_RS09325	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HUT14_RS09330	COG0723	plastoquinol--plastocyanin reductase activity
HUT14_RS09335	COG2010	Cytochrome c
HUT14_RS09340	COG1845	cytochrome c oxidase, subunit III
HUT14_RS09350	COG1376	ErfK ybiS ycfS ynhG family protein
HUT14_RS09360	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HUT14_RS09365	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HUT14_RS09375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUT14_RS09395	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HUT14_RS09400	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HUT14_RS09405	COG2197	response regulator
HUT14_RS09450	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
HUT14_RS09460	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HUT14_RS09475	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HUT14_RS09480	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HUT14_RS09485	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUT14_RS09495	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HUT14_RS09545	COG0321	lipoyl(octanoyl) transferase activity
HUT14_RS09550	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HUT14_RS09570	COG0174	glutamine synthetase
HUT14_RS09580	COG0501	Belongs to the peptidase M48B family
HUT14_RS09610	COG0745	RESPONSE REGULATOR receiver
HUT14_RS09625	COG2197	response regulator
HUT14_RS09675	COG0366	Alpha amylase catalytic
HUT14_RS09680	COG3833	ABC-type maltose transport systems, permease component
HUT14_RS09685	COG1175	transmembrane transport
HUT14_RS09690	COG1653	transport
HUT14_RS09695	COG1609	Transcriptional regulator
HUT14_RS09705	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
HUT14_RS09730	COG0174	glutamine synthetase
HUT14_RS09735	COG1959	2 iron, 2 sulfur cluster binding
HUT14_RS09750	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HUT14_RS09750	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HUT14_RS09765	COG0477	Major facilitator Superfamily
HUT14_RS09770	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
HUT14_RS09790	COG1994	Peptidase M50
HUT14_RS09835	COG2837	iron assimilation
HUT14_RS09840	COG0672	)-iron permease
HUT14_RS09855	COG0584	glycerophosphoryl diester phosphodiesterase
HUT14_RS09860	COG1309	transcriptional regulator
HUT14_RS09870	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HUT14_RS09875	COG2814	Major facilitator Superfamily
HUT14_RS09895	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HUT14_RS09900	COG1414	Transcriptional regulator
HUT14_RS09910	COG2409	Drug exporters of the RND superfamily
HUT14_RS09945	COG1028	Short-chain dehydrogenase reductase Sdr
HUT14_RS09950	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HUT14_RS09955	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HUT14_RS09960	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUT14_RS09975	COG0183	Belongs to the thiolase family
HUT14_RS09980	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUT14_RS09985	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUT14_RS10015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT14_RS10020	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT14_RS10035	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT14_RS10045	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT14_RS10045	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT14_RS10050	COG2124	cytochrome p450
HUT14_RS10065	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HUT14_RS10085	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUT14_RS10090	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUT14_RS10125	COG1652	LysM domain
HUT14_RS10210	COG1201	RNA secondary structure unwinding
HUT14_RS10215	COG2124	cytochrome p450
HUT14_RS10220	COG2124	cytochrome p450
HUT14_RS10295	COG3022	response to hydroperoxide
HUT14_RS10300	COG0800	Aldolase
HUT14_RS10315	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HUT14_RS10330	COG2030	dehydratase
HUT14_RS10335	COG4585	Histidine kinase
HUT14_RS10340	COG2197	response regulator
HUT14_RS10350	COG0477	Major facilitator Superfamily
HUT14_RS10385	COG0438	transferase activity, transferring glycosyl groups
HUT14_RS10390	COG1309	transcriptional regulator
HUT14_RS10415	COG3845	ABC transporter
HUT14_RS10440	COG4122	O-methyltransferase activity
HUT14_RS10480	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUT14_RS10540	COG0586	Pfam SNARE associated Golgi protein
HUT14_RS10550	COG1358	cellular component organization or biogenesis
HUT14_RS10595	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HUT14_RS10605	COG0477	Major facilitator Superfamily
HUT14_RS10610	COG1309	transcriptional regulator
HUT14_RS10625	COG0789	Transcriptional regulator
HUT14_RS10675	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUT14_RS10680	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUT14_RS10685	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUT14_RS10710	COG1280	lysine exporter protein (LysE YggA)
HUT14_RS10720	COG2130	NADP-dependent
HUT14_RS10750	COG4213	ABC transporter substrate-binding protein
HUT14_RS10760	COG4214	carbohydrate transport
HUT14_RS10770	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HUT14_RS10775	COG3507	Belongs to the glycosyl hydrolase 43 family
HUT14_RS10810	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HUT14_RS10835	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HUT14_RS10845	COG1127	ABC transporter
HUT14_RS10880	COG0395	ABC-type sugar transport system, permease component
HUT14_RS10885	COG1175	transmembrane transport
HUT14_RS10915	COG3386	PFAM SMP-30 Gluconolaconase
HUT14_RS10920	COG1414	Transcriptional regulator
HUT14_RS10940	COG2186	Transcriptional regulator
HUT14_RS10950	COG0318	PFAM AMP-dependent synthetase and ligase
HUT14_RS10955	COG0825	malonyl-CoA metabolic process
HUT14_RS10955	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HUT14_RS10960	COG1077	Cell shape determining protein MreB Mrl
HUT14_RS11005	COG1070	Carbohydrate kinase
HUT14_RS11020	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HUT14_RS11025	COG0358	DNA primase activity
HUT14_RS11035	COG0232	Belongs to the dGTPase family. Type 2 subfamily
HUT14_RS11045	COG2949	membrane
HUT14_RS11050	COG0243	molybdopterin cofactor binding
HUT14_RS11075	COG1733	regulation of RNA biosynthetic process
HUT14_RS11095	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HUT14_RS11095	COG2146	nitrite reductase [NAD(P)H] activity
HUT14_RS11100	COG2146	nitrite reductase [NAD(P)H] activity
HUT14_RS11100	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HUT14_RS11120	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HUT14_RS11120	COG0574	Belongs to the PEP-utilizing enzyme family
HUT14_RS11145	COG0423	glycine-tRNA ligase activity
HUT14_RS11150	COG0803	Belongs to the bacterial solute-binding protein 9 family
HUT14_RS11150	COG3443	Belongs to the bacterial solute-binding protein 9 family
HUT14_RS11155	COG1120	ATPase activity
HUT14_RS11160	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HUT14_RS11175	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HUT14_RS11180	COG1381	Involved in DNA repair and RecF pathway recombination
HUT14_RS11220	COG2197	response regulator
HUT14_RS11225	COG4585	Histidine kinase
HUT14_RS11230	COG2409	Drug exporters of the RND superfamily
HUT14_RS11275	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HUT14_RS11295	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HUT14_RS11305	COG2315	Protein conserved in bacteria
HUT14_RS11315	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HUT14_RS11325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUT14_RS11330	COG4948	Mandelate Racemase Muconate Lactonizing
HUT14_RS11335	COG1414	Transcriptional regulator
HUT14_RS11345	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HUT14_RS11350	COG1234	tRNA 3'-trailer cleavage
HUT14_RS11355	COG0537	adenosine 5'-monophosphoramidase activity
HUT14_RS11360	COG0793	Belongs to the peptidase S41A family
HUT14_RS11360	COG4946	Tricorn protease homolog
HUT14_RS11380	COG0484	heat shock protein binding
HUT14_RS11385	COG1420	regulation of RNA biosynthetic process
HUT14_RS11415	COG0481	GTPase activity
HUT14_RS11420	COG0268	Binds directly to 16S ribosomal RNA
HUT14_RS11450	COG1307	EDD domain protein, DegV family
HUT14_RS11460	COG0495	leucyl-tRNA aminoacylation
HUT14_RS11470	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HUT14_RS11495	COG0588	phosphoglycerate mutase activity
HUT14_RS11500	COG0799	negative regulation of ribosome biogenesis
HUT14_RS11510	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HUT14_RS11520	COG0501	Belongs to the peptidase M48B family
HUT14_RS11535	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HUT14_RS11545	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HUT14_RS11560	COG1215	transferase activity, transferring glycosyl groups
HUT14_RS11575	COG3540	Alkaline phosphatase
HUT14_RS11585	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HUT14_RS11590	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HUT14_RS11595	COG0261	This protein binds to 23S rRNA in the presence of protein L20
HUT14_RS11620	COG1530	ribonuclease E activity
HUT14_RS11650	COG0772	Belongs to the SEDS family
HUT14_RS11655	COG0768	penicillin binding
HUT14_RS11670	COG1077	Cell shape determining protein MreB Mrl
HUT14_RS11675	COG0105	UTP biosynthetic process
HUT14_RS11685	COG0285	dihydrofolate synthase activity
HUT14_RS11695	COG0525	valine-tRNA ligase activity
HUT14_RS11705	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HUT14_RS11710	COG0740	serine-type endopeptidase activity
HUT14_RS11715	COG0740	serine-type endopeptidase activity
HUT14_RS11720	COG0544	peptidyl-prolyl cis-trans isomerase activity
HUT14_RS11740	COG3594	Acyltransferase
HUT14_RS11755	COG4552	Acetyltransferase involved in intracellular survival and related
HUT14_RS11770	COG1113	amino acid transport
HUT14_RS11780	COG1113	amino acid transport
HUT14_RS11790	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
HUT14_RS11850	COG1309	transcriptional regulator
HUT14_RS11860	COG0697	spore germination
HUT14_RS11865	COG1846	Transcriptional regulator
HUT14_RS11885	COG3525	Glycosyl hydrolase, family 20, catalytic domain
HUT14_RS11885	COG3291	Pkd domain containing protein
HUT14_RS11895	COG1136	(ABC) transporter
HUT14_RS11910	COG0668	transmembrane transport
HUT14_RS11920	COG1486	melibiose metabolic process
HUT14_RS11965	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HUT14_RS11985	COG1136	(ABC) transporter
HUT14_RS12050	COG1028	Short-chain dehydrogenase reductase Sdr
HUT14_RS12050	COG3321	synthase
HUT14_RS12050	COG0604	alcohol dehydrogenase
HUT14_RS12070	COG0629	single-stranded DNA binding
HUT14_RS12090	COG2267	carboxylic ester hydrolase activity
HUT14_RS12120	COG2304	oxidoreductase activity
HUT14_RS12150	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HUT14_RS12160	COG0728	peptidoglycan biosynthetic process
HUT14_RS12170	COG0438	transferase activity, transferring glycosyl groups
HUT14_RS12190	COG0492	ferredoxin-NADP+ reductase activity
HUT14_RS12205	COG1131	(ABC) transporter
HUT14_RS12240	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HUT14_RS12300	COG1609	Transcriptional regulator
HUT14_RS12305	COG1129	ABC transporter
HUT14_RS12315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUT14_RS12320	COG1869	D-ribose catabolic process
HUT14_RS12375	COG1674	ftsk spoiiie
HUT14_RS12395	COG0673	inositol 2-dehydrogenase activity
HUT14_RS12400	COG1609	Transcriptional regulator
HUT14_RS12415	COG0697	spore germination
HUT14_RS12425	COG1472	Belongs to the glycosyl hydrolase 3 family
HUT14_RS12455	COG2356	endonuclease I
HUT14_RS12465	COG0028	Belongs to the TPP enzyme family
HUT14_RS12490	COG1946	Acyl-CoA thioesterase
HUT14_RS12500	COG1309	transcriptional regulator
HUT14_RS12505	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUT14_RS12520	COG1960	acyl-CoA dehydrogenase activity
HUT14_RS12535	COG3409	Peptidoglycan-binding domain 1 protein
HUT14_RS12560	COG3486	L-lysine 6-monooxygenase (NADPH) activity
HUT14_RS12585	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HUT14_RS12590	COG0589	response to stress
HUT14_RS12595	COG4977	sequence-specific DNA binding
HUT14_RS12600	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HUT14_RS12625	COG0395	ABC-type sugar transport system, permease component
HUT14_RS12635	COG3979	chitinase
HUT14_RS12645	COG0745	RESPONSE REGULATOR receiver
HUT14_RS12655	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HUT14_RS12670	COG0406	alpha-ribazole phosphatase activity
HUT14_RS12720	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT14_RS12735	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HUT14_RS12750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUT14_RS12755	COG0765	amino acid transport
HUT14_RS12760	COG0765	amino acid transport
HUT14_RS12765	COG1126	abc transporter atp-binding protein
HUT14_RS12775	COG3397	chitin binding
HUT14_RS12820	COG1940	carbohydrate kinase activity
HUT14_RS12825	COG0673	inositol 2-dehydrogenase activity
HUT14_RS12830	COG4702	Belongs to the UPF0303 family
HUT14_RS12835	COG0706	membrane insertase activity
HUT14_RS12860	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
HUT14_RS12930	COG3467	pyridoxamine 5'-phosphate
HUT14_RS12935	COG1309	transcriptional regulator
HUT14_RS12940	COG4106	trans-aconitate 2-methyltransferase activity
HUT14_RS12945	COG3226	Transcriptional regulator
HUT14_RS12975	COG2271	Major facilitator Superfamily
HUT14_RS12980	COG2733	membrane
HUT14_RS12995	COG4555	ABC transporter
HUT14_RS13010	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HUT14_RS13050	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HUT14_RS13060	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HUT14_RS13065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUT14_RS13070	COG1263	PTS System
HUT14_RS13075	COG1263	PTS System
HUT14_RS13080	COG1234	tRNA 3'-trailer cleavage
HUT14_RS13105	COG1113	amino acid transport
HUT14_RS13115	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
HUT14_RS13125	COG1335	isochorismatase
HUT14_RS13155	COG0277	FAD linked oxidase domain protein
HUT14_RS13165	COG3185	4-Hydroxyphenylpyruvate dioxygenase
HUT14_RS13175	COG1174	glycine betaine transport
HUT14_RS13185	COG1174	glycine betaine transport
HUT14_RS13190	COG1732	Glycine betaine
HUT14_RS13205	COG1061	Type III restriction enzyme res subunit
HUT14_RS13210	COG3654	unkown
HUT14_RS13240	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HUT14_RS13255	COG3525	Glycosyl hydrolase, family 20, catalytic domain
HUT14_RS13260	COG0395	ABC-type sugar transport system, permease component
HUT14_RS13280	COG1678	Uncharacterized ACR, COG1678
HUT14_RS13285	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HUT14_RS13290	COG0776	regulation of translation
HUT14_RS13300	COG3973	AAA domain
HUT14_RS13325	COG2223	nitrite transmembrane transporter activity
HUT14_RS13390	COG0583	DNA-binding transcription factor activity
HUT14_RS13400	COG1609	Transcriptional regulator
HUT14_RS13415	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HUT14_RS13420	COG0793	Belongs to the peptidase S41A family
HUT14_RS13430	COG2884	Cell division ATP-binding protein ftsE
HUT14_RS13445	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HUT14_RS13450	COG0515	serine threonine protein kinase
HUT14_RS13455	COG0515	serine threonine protein kinase
HUT14_RS13470	COG1175	transmembrane transport
HUT14_RS13475	COG0395	ABC-type sugar transport system, permease component
HUT14_RS13480	COG0463	Glycosyl transferase, family 2
HUT14_RS13480	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HUT14_RS13485	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HUT14_RS13490	COG1216	Glycosyl transferase, family 2
HUT14_RS13505	COG1764	response to oxidative stress
HUT14_RS13510	COG1846	Transcriptional regulator
HUT14_RS13515	COG1215	transferase activity, transferring glycosyl groups
HUT14_RS13540	COG1134	teichoic acid transport
HUT14_RS13545	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HUT14_RS13550	COG1215	transferase activity, transferring glycosyl groups
HUT14_RS13560	COG2902	Dehydrogenase
HUT14_RS13580	COG0653	protein targeting
HUT14_RS13590	COG3214	Protein conserved in bacteria
HUT14_RS13595	COG2197	response regulator
HUT14_RS13600	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HUT14_RS13610	COG0823	Involved in the tonB-independent uptake of proteins
HUT14_RS13615	COG5002	protein histidine kinase activity
HUT14_RS13620	COG0745	RESPONSE REGULATOR receiver
HUT14_RS13625	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HUT14_RS13645	COG0714	Associated with various cellular activities
HUT14_RS13685	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HUT14_RS13695	COG1482	cell wall glycoprotein biosynthetic process
HUT14_RS13705	COG2835	tetraacyldisaccharide 4'-kinase activity
HUT14_RS13710	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HUT14_RS13715	COG1620	l-lactate permease
HUT14_RS13750	COG0391	Required for morphogenesis under gluconeogenic growth conditions
HUT14_RS13755	COG0778	Nitroreductase
HUT14_RS13755	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
HUT14_RS13780	COG1316	TRANSCRIPTIONal
HUT14_RS13785	COG1316	TRANSCRIPTIONal
HUT14_RS13790	COG1316	TRANSCRIPTIONal
HUT14_RS13795	COG1316	TRANSCRIPTIONal
HUT14_RS13800	COG0739	heme binding
HUT14_RS13810	COG1316	TRANSCRIPTIONal
HUT14_RS13820	COG1316	TRANSCRIPTIONal
HUT14_RS13830	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HUT14_RS13835	COG1960	acyl-CoA dehydrogenase activity
HUT14_RS13840	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HUT14_RS13870	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HUT14_RS13885	COG2205	protein histidine kinase activity
HUT14_RS13890	COG0745	RESPONSE REGULATOR receiver
HUT14_RS13895	COG3104	oligopeptide transport
HUT14_RS13905	COG1366	Belongs to the anti-sigma-factor antagonist family
HUT14_RS13910	COG1191	sigma factor activity
HUT14_RS13915	COG1228	amidohydrolase
HUT14_RS13930	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HUT14_RS13950	COG1316	TRANSCRIPTIONal
HUT14_RS13965	COG2755	lipolytic protein G-D-S-L family
HUT14_RS13970	COG0183	Belongs to the thiolase family
HUT14_RS14005	COG1136	(ABC) transporter
HUT14_RS14005	COG0577	efflux transmembrane transporter activity
HUT14_RS14010	COG0577	efflux transmembrane transporter activity
HUT14_RS14015	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HUT14_RS14020	COG1252	NADH dehydrogenase
HUT14_RS14040	COG0148	phosphopyruvate hydratase activity
HUT14_RS14115	COG1136	(ABC) transporter
HUT14_RS14115	COG0577	efflux transmembrane transporter activity
HUT14_RS14120	COG1136	(ABC) transporter
HUT14_RS14150	COG4585	Histidine kinase
HUT14_RS14165	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HUT14_RS14170	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HUT14_RS14175	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HUT14_RS14180	COG0193	aminoacyl-tRNA hydrolase activity
HUT14_RS14190	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HUT14_RS14200	COG1309	transcriptional regulator
HUT14_RS14205	COG4106	trans-aconitate 2-methyltransferase activity
HUT14_RS14215	COG2197	response regulator
HUT14_RS14225	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HUT14_RS14265	COG0488	(ABC) transporter
HUT14_RS14270	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HUT14_RS14275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HUT14_RS14280	COG0084	hydrolase, TatD family'
HUT14_RS14315	COG0310	cobalt ion transport
HUT14_RS14325	COG1122	ATPase activity
HUT14_RS14330	COG1846	Transcriptional regulator
HUT14_RS14360	COG2409	Drug exporters of the RND superfamily
HUT14_RS14370	COG4946	Tricorn protease homolog
HUT14_RS14370	COG0793	Belongs to the peptidase S41A family
HUT14_RS14385	COG2267	carboxylic ester hydrolase activity
HUT14_RS14390	COG2072	flavoprotein involved in K transport
HUT14_RS14405	COG0708	Exodeoxyribonuclease III
HUT14_RS14445	COG0521	Mo-molybdopterin cofactor biosynthetic process
HUT14_RS14445	COG0315	cyclic pyranopterin monophosphate synthase activity
HUT14_RS14450	COG0315	cyclic pyranopterin monophosphate synthase activity
HUT14_RS14460	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HUT14_RS14465	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HUT14_RS14475	COG3263	regulation of cellular component size
HUT14_RS14490	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HUT14_RS14525	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HUT14_RS14525	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HUT14_RS14525	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUT14_RS14535	COG1349	DNA-binding transcription factor activity
HUT14_RS14540	COG0477	Major facilitator Superfamily
HUT14_RS14560	COG1247	-acetyltransferase
HUT14_RS14565	COG3384	dioxygenase
HUT14_RS14570	COG1846	Transcriptional regulator
HUT14_RS14685	COG2188	Transcriptional regulator
HUT14_RS14700	COG1487	ribonuclease activity
HUT14_RS14730	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HUT14_RS14750	COG0076	glutamate decarboxylase activity
HUT14_RS14825	COG0386	Belongs to the glutathione peroxidase family
HUT14_RS14850	COG1686	Belongs to the peptidase S11 family
HUT14_RS14875	COG2815	serine threonine protein kinase
HUT14_RS14875	COG0515	serine threonine protein kinase
HUT14_RS14895	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
HUT14_RS14915	COG3629	intracellular signal transduction
HUT14_RS14915	COG3903	Transcriptional regulator
HUT14_RS14930	COG0515	serine threonine protein kinase
HUT14_RS14930	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HUT14_RS14940	COG1309	transcriptional regulator
HUT14_RS14950	COG0259	pyridoxamine-phosphate oxidase activity
HUT14_RS14960	COG2072	flavoprotein involved in K transport
HUT14_RS14965	COG2271	Major facilitator Superfamily
HUT14_RS15040	COG2945	thiolester hydrolase activity
HUT14_RS15040	COG0596	Alpha beta hydrolase
HUT14_RS15050	COG4821	SIS domain
HUT14_RS15065	COG2252	PERMEase
HUT14_RS15075	COG0259	pyridoxamine-phosphate oxidase activity
HUT14_RS15090	COG0318	PFAM AMP-dependent synthetase and ligase
HUT14_RS15105	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUT14_RS15120	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
HUT14_RS15130	COG5006	permease, DMT superfamily
HUT14_RS15140	COG0277	FAD linked oxidase domain protein
HUT14_RS15140	COG0247	lactate metabolic process
HUT14_RS15175	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HUT14_RS15210	COG0667	Aldo Keto reductase
HUT14_RS15240	COG2252	PERMEase
HUT14_RS15250	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HUT14_RS15260	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HUT14_RS15260	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HUT14_RS15275	COG2267	carboxylic ester hydrolase activity
HUT14_RS15280	COG0739	heme binding
HUT14_RS15310	COG2814	Major facilitator Superfamily
HUT14_RS15320	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HUT14_RS15325	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
HUT14_RS15330	COG1278	Cold shock
HUT14_RS15355	COG1061	Type III restriction enzyme res subunit
HUT14_RS15365	COG3973	AAA domain
HUT14_RS15400	COG1737	Transcriptional regulator
HUT14_RS15405	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HUT14_RS15430	COG0459	protein refolding
HUT14_RS15435	COG1278	Cold shock
HUT14_RS15450	COG0463	Glycosyl transferase, family 2
HUT14_RS15475	COG1940	carbohydrate kinase activity
HUT14_RS15495	COG5001	Diguanylate cyclase
HUT14_RS15495	COG3300	MHYT domain
HUT14_RS15510	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HUT14_RS15560	COG2378	regulation of single-species biofilm formation
HUT14_RS15565	COG3842	ATPase activity
HUT14_RS15590	COG0215	cysteine-tRNA ligase activity
HUT14_RS15595	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
HUT14_RS15600	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
HUT14_RS15605	COG1329	Transcriptional regulator
HUT14_RS15620	COG5002	protein histidine kinase activity
HUT14_RS15640	COG0588	phosphoglycerate mutase activity
HUT14_RS15655	COG1396	sequence-specific DNA binding
HUT14_RS15725	COG0438	transferase activity, transferring glycosyl groups
HUT14_RS15765	COG2318	DinB family
HUT14_RS15770	COG0395	ABC-type sugar transport system, permease component
HUT14_RS15775	COG1175	transmembrane transport
HUT14_RS15780	COG1653	transport
HUT14_RS15785	COG0156	8-amino-7-oxononanoate synthase activity
HUT14_RS15790	COG2186	Transcriptional regulator
HUT14_RS15795	COG3973	AAA domain
HUT14_RS15815	COG0546	phosphoglycolate phosphatase activity
HUT14_RS15820	COG2188	Transcriptional regulator
HUT14_RS15835	COG4552	Acetyltransferase involved in intracellular survival and related
HUT14_RS15845	COG1490	D-aminoacyl-tRNA deacylase activity
HUT14_RS15855	COG0735	belongs to the Fur family
HUT14_RS15860	COG3485	protocatechuate 3,4-dioxygenase
HUT14_RS15895	COG2897	thiosulfate sulfurtransferase activity
HUT14_RS15920	COG0745	RESPONSE REGULATOR receiver
HUT14_RS15925	COG1609	Transcriptional regulator
HUT14_RS15930	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUT14_RS15945	COG3866	Pectate lyase
HUT14_RS15980	COG0737	Belongs to the 5'-nucleotidase family
HUT14_RS15985	COG0456	acetyltransferase
HUT14_RS16020	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HUT14_RS16050	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HUT14_RS16055	COG0306	phosphate transporter
HUT14_RS16065	COG1937	Protein conserved in bacteria
HUT14_RS16085	COG0671	phosphoesterase, PA-phosphatase related
HUT14_RS16135	COG1131	(ABC) transporter
HUT14_RS16145	COG4585	Histidine kinase
HUT14_RS16150	COG2197	response regulator
HUT14_RS16170	COG1846	Transcriptional regulator
HUT14_RS16185	COG1252	NADH dehydrogenase
HUT14_RS16205	COG0579	oxidoreductase
HUT14_RS16210	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HUT14_RS16230	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HUT14_RS16230	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HUT14_RS16235	COG2197	response regulator
HUT14_RS16255	COG0513	Belongs to the DEAD box helicase family
HUT14_RS16290	COG1643	Atp-dependent helicase
HUT14_RS16310	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HUT14_RS16320	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
HUT14_RS16340	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HUT14_RS16345	COG0047	phosphoribosylformylglycinamidine synthase activity
HUT14_RS16350	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HUT14_RS16385	COG2197	response regulator
HUT14_RS16395	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
HUT14_RS16410	COG0151	Belongs to the GarS family
HUT14_RS16450	COG0438	transferase activity, transferring glycosyl groups
HUT14_RS16455	COG0438	transferase activity, transferring glycosyl groups
HUT14_RS16465	COG1028	Short-chain dehydrogenase reductase Sdr
HUT14_RS16500	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HUT14_RS16535	COG1191	sigma factor activity
HUT14_RS16540	COG1191	sigma factor activity
HUT14_RS16555	COG0477	Major facilitator Superfamily
HUT14_RS16575	COG3467	pyridoxamine 5'-phosphate
HUT14_RS16580	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HUT14_RS16590	COG2205	protein histidine kinase activity
HUT14_RS16595	COG0745	RESPONSE REGULATOR receiver
HUT14_RS16615	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HUT14_RS16645	COG0784	Response regulator, receiver
HUT14_RS16650	COG0318	PFAM AMP-dependent synthetase and ligase
HUT14_RS16655	COG1595	DNA-templated transcription, initiation
HUT14_RS16695	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUT14_RS16710	COG0653	protein targeting
HUT14_RS16725	COG0006	proline dipeptidase activity
HUT14_RS16745	COG1999	signal sequence binding
HUT14_RS16760	COG2837	iron assimilation
HUT14_RS16770	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HUT14_RS16775	COG0561	phosphatase activity
HUT14_RS16795	COG1131	(ABC) transporter
HUT14_RS16805	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
HUT14_RS16815	COG0561	phosphatase activity
HUT14_RS16825	COG4988	ABC transporter
HUT14_RS16830	COG1294	oxidase, subunit
HUT14_RS16835	COG1271	oxidase subunit
HUT14_RS16840	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HUT14_RS16845	COG1609	Transcriptional regulator
HUT14_RS16850	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HUT14_RS16865	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HUT14_RS16890	COG0662	Cupin 2, conserved barrel domain protein
HUT14_RS16895	COG1950	PFAM Membrane protein of
HUT14_RS16900	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HUT14_RS16905	COG0626	cystathionine gamma-synthase activity
HUT14_RS16930	COG2814	Major facilitator Superfamily
HUT14_RS16955	COG0305	Participates in initiation and elongation during chromosome replication
HUT14_RS16965	COG0359	binds to the 23S rRNA
HUT14_RS16970	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HUT14_RS16975	COG0629	single-stranded DNA binding
HUT14_RS16980	COG0360	Binds together with S18 to 16S ribosomal RNA
HUT14_RS17005	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HUT14_RS17015	COG1260	myo-inositol-1-phosphate synthase
HUT14_RS17030	COG0617	tRNA 3'-terminal CCA addition
HUT14_RS17050	COG1595	DNA-templated transcription, initiation
HUT14_RS17060	COG0492	ferredoxin-NADP+ reductase activity
HUT14_RS17065	COG3118	belongs to the thioredoxin family
HUT14_RS17080	COG1192	Involved in chromosome partitioning
HUT14_RS17085	COG0357	Ribosomal RNA small subunit methyltransferase G
HUT14_RS17095	COG0706	membrane insertase activity
HUT14_RS17100	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
HUT14_RS17105	COG0594	ribonuclease P activity
HUT14_RS17110	COG0230	Belongs to the bacterial ribosomal protein bL34 family
HUT14_RS17115	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HUT14_RS17120	COG0592	DNA-directed DNA polymerase activity
HUT14_RS17125	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
HUT14_RS17130	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HUT14_RS17135	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
HUT14_RS17140	COG0187	DNA topoisomerase II activity
HUT14_RS17145	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HUT14_RS17180	COG0515	serine threonine protein kinase
HUT14_RS17205	COG0705	Rhomboid family
HUT14_RS17230	COG3764	Sortase (surface protein transpeptidase)
HUT14_RS17235	COG3764	Sortase (surface protein transpeptidase)
HUT14_RS17240	COG0515	serine threonine protein kinase
HUT14_RS17245	COG0768	penicillin binding
HUT14_RS17260	COG1716	ATPase activity
HUT14_RS17265	COG1716	ATPase activity
HUT14_RS17275	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUT14_RS17275	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HUT14_RS17290	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HUT14_RS17295	COG1937	Protein conserved in bacteria
HUT14_RS17305	COG1937	Protein conserved in bacteria
HUT14_RS17320	COG1136	(ABC) transporter
HUT14_RS17320	COG0577	efflux transmembrane transporter activity
HUT14_RS17330	COG2197	response regulator
HUT14_RS17360	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUT14_RS17365	COG2151	metal-sulfur cluster biosynthetic enzyme
HUT14_RS17370	COG3396	Phenylacetate-CoA oxygenase
HUT14_RS17375	COG3460	Phenylacetate-CoA oxygenase
HUT14_RS17380	COG3396	Phenylacetate-CoA oxygenase
HUT14_RS17405	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUT14_RS17410	COG1309	transcriptional regulator
HUT14_RS17415	COG1522	sequence-specific DNA binding
HUT14_RS17440	COG0303	'Molybdopterin
HUT14_RS17460	COG3321	synthase
HUT14_RS17460	COG0604	alcohol dehydrogenase
HUT14_RS17460	COG1028	Short-chain dehydrogenase reductase Sdr
HUT14_RS17475	COG0515	serine threonine protein kinase
HUT14_RS17480	COG0515	serine threonine protein kinase
HUT14_RS17490	COG0022	dehydrogenase e1 component
HUT14_RS17495	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUT14_RS17540	COG1362	aminopeptidase activity
HUT14_RS17545	COG1960	acyl-CoA dehydrogenase activity
HUT14_RS17555	COG1741	Belongs to the pirin family
HUT14_RS17565	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HUT14_RS17580	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HUT14_RS17595	COG0583	DNA-binding transcription factor activity
HUT14_RS17650	COG0366	Alpha amylase catalytic
HUT14_RS17685	COG1278	Cold shock
HUT14_RS17695	COG0583	DNA-binding transcription factor activity
HUT14_RS17705	COG2367	Beta-lactamase
HUT14_RS17715	COG4213	ABC transporter substrate-binding protein
HUT14_RS17725	COG2755	lipolytic protein G-D-S-L family
HUT14_RS17725	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HUT14_RS17730	COG1595	DNA-templated transcription, initiation
HUT14_RS17735	COG1252	NADH dehydrogenase
HUT14_RS17750	COG1720	tRNA m6t6A37 methyltransferase activity
HUT14_RS17760	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HUT14_RS17810	COG3629	intracellular signal transduction
HUT14_RS17810	COG3903	Transcriptional regulator
HUT14_RS17840	COG0463	Glycosyl transferase, family 2
HUT14_RS17865	COG0475	glutathione-regulated potassium exporter activity
HUT14_RS17870	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HUT14_RS17900	COG2197	response regulator
HUT14_RS17905	COG4585	Histidine kinase
HUT14_RS17925	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HUT14_RS17935	COG0717	Belongs to the dCTP deaminase family
HUT14_RS17940	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
HUT14_RS17960	COG2181	nitrate reductase activity
HUT14_RS17960	COG0247	lactate metabolic process
HUT14_RS17965	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HUT14_RS17970	COG0443	Heat shock 70 kDa protein
HUT14_RS17975	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HUT14_RS17980	COG0484	heat shock protein binding
HUT14_RS17985	COG0789	Transcriptional regulator
HUT14_RS17990	COG4213	ABC transporter substrate-binding protein
HUT14_RS18025	COG0542	response to heat
HUT14_RS18060	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HUT14_RS18070	COG2017	converts alpha-aldose to the beta-anomer
HUT14_RS18075	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HUT14_RS18080	COG0191	fructose-bisphosphate aldolase activity
HUT14_RS18085	COG0477	Major facilitator Superfamily
HUT14_RS18120	COG4585	Histidine kinase
HUT14_RS18125	COG2197	response regulator
HUT14_RS18130	COG4585	Histidine kinase
HUT14_RS18135	COG2197	response regulator
HUT14_RS18145	COG3559	Exporter of polyketide antibiotics
HUT14_RS18150	COG1131	(ABC) transporter
HUT14_RS18170	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HUT14_RS18185	COG1802	Transcriptional regulator
HUT14_RS18195	COG0693	protein deglycase activity
HUT14_RS18210	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HUT14_RS18220	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HUT14_RS18225	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HUT14_RS18275	COG0701	Predicted permease
HUT14_RS18300	COG3321	synthase
HUT14_RS18300	COG1028	Short-chain dehydrogenase reductase Sdr
HUT14_RS18300	COG0604	alcohol dehydrogenase
HUT14_RS18310	COG3629	intracellular signal transduction
HUT14_RS18310	COG3903	Transcriptional regulator
HUT14_RS18430	COG0154	amidase activity
HUT14_RS18435	COG2217	Heavy metal translocating P-type atpase
HUT14_RS18470	COG3903	Transcriptional regulator
HUT14_RS18470	COG3629	intracellular signal transduction
HUT14_RS18490	COG3629	intracellular signal transduction
HUT14_RS18490	COG3903	Transcriptional regulator
HUT14_RS18515	COG1408	metallophosphoesterase
HUT14_RS18555	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HUT14_RS18565	COG0003	Pfam Anion-transporting ATPase
HUT14_RS18590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUT14_RS18615	COG0596	Alpha beta hydrolase
HUT14_RS18625	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HUT14_RS18630	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUT14_RS18700	COG1366	Belongs to the anti-sigma-factor antagonist family
HUT14_RS18710	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
HUT14_RS18720	COG2264	protein methyltransferase activity
HUT14_RS18730	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HUT14_RS18730	COG1754	DNA topoisomerase type I activity
HUT14_RS18735	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HUT14_RS18770	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HUT14_RS18770	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HUT14_RS18810	COG1012	belongs to the aldehyde dehydrogenase family
HUT14_RS18835	COG0789	Transcriptional regulator
HUT14_RS18840	COG0586	Pfam SNARE associated Golgi protein
HUT14_RS18850	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HUT14_RS18855	COG2027	D-alanyl-D-alanine carboxypeptidase
HUT14_RS18865	COG0037	tRNA processing
HUT14_RS18880	COG0302	gtp cyclohydrolase
HUT14_RS18895	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HUT14_RS18925	COG0649	NAD binding
HUT14_RS18945	COG1660	Displays ATPase and GTPase activities
HUT14_RS18965	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HUT14_RS18970	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HUT14_RS18980	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HUT14_RS19000	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HUT14_RS19025	COG0739	heme binding
HUT14_RS19040	COG2205	protein histidine kinase activity
HUT14_RS19045	COG0745	RESPONSE REGULATOR receiver
HUT14_RS19055	COG1595	DNA-templated transcription, initiation
HUT14_RS19060	COG1194	a g-specific adenine glycosylase
HUT14_RS19065	COG4585	Histidine kinase
HUT14_RS19085	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HUT14_RS19105	COG0248	Ppx GppA phosphatase
HUT14_RS19110	COG1082	Xylose isomerase domain protein TIM barrel
HUT14_RS19115	COG1309	transcriptional regulator
HUT14_RS19120	COG0129	dihydroxy-acid dehydratase activity
HUT14_RS19145	COG0842	Transport permease protein
HUT14_RS19145	COG1129	ABC transporter
HUT14_RS19155	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HUT14_RS19170	COG0180	Tryptophanyl-tRNA synthetase
HUT14_RS19200	COG0123	including yeast histone deacetylase and acetoin utilization protein
HUT14_RS19250	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HUT14_RS19255	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HUT14_RS19260	COG0181	hydroxymethylbilane synthase activity
HUT14_RS19265	COG1648	precorrin-2 dehydrogenase activity
HUT14_RS19265	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HUT14_RS19300	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HUT14_RS19330	COG0113	porphobilinogen synthase activity
HUT14_RS19345	COG2814	Major facilitator Superfamily
HUT14_RS19345	COG0477	Major facilitator Superfamily
HUT14_RS19355	COG2159	amidohydrolase
HUT14_RS19360	COG0745	RESPONSE REGULATOR receiver
HUT14_RS19365	COG2205	protein histidine kinase activity
HUT14_RS19380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT14_RS19385	COG0018	arginyl-trna synthetase
HUT14_RS19390	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
HUT14_RS19410	COG1690	Belongs to the RtcB family
HUT14_RS19420	COG1742	UPF0060 membrane protein
HUT14_RS19425	COG1846	Transcriptional regulator
HUT14_RS19430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT14_RS19445	COG2205	protein histidine kinase activity
HUT14_RS19450	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUT14_RS19455	COG2340	Cysteine-rich secretory protein family
HUT14_RS19490	COG2197	response regulator
HUT14_RS19510	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HUT14_RS19515	COG0406	alpha-ribazole phosphatase activity
HUT14_RS19530	COG0785	Cytochrome C biogenesis protein
HUT14_RS19535	COG1333	cytochrome c biogenesis protein
HUT14_RS19540	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HUT14_RS19585	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HUT14_RS19590	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HUT14_RS19600	COG0163	prenyltransferase activity
HUT14_RS19610	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
HUT14_RS19625	COG1301	dicarboxylic acid transport
HUT14_RS19650	COG1309	transcriptional regulator
HUT14_RS19665	COG0183	Belongs to the thiolase family
HUT14_RS19680	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
HUT14_RS19690	COG1674	ftsk spoiiie
HUT14_RS19700	COG4842	Belongs to the WXG100 family
HUT14_RS19770	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
HUT14_RS19820	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
HUT14_RS19830	COG3979	chitinase
HUT14_RS19850	COG2226	methyltransferase
HUT14_RS19880	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT14_RS19885	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT14_RS19890	COG0649	NAD binding
HUT14_RS19900	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HUT14_RS19905	COG1034	ATP synthesis coupled electron transport
HUT14_RS19910	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HUT14_RS19915	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT14_RS19920	COG0839	Belongs to the complex I subunit 6 family
HUT14_RS19925	COG0713	ATP synthesis coupled electron transport
HUT14_RS19930	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HUT14_RS19940	COG1007	ATP synthesis coupled electron transport
HUT14_RS19945	COG0514	ATP-dependent DNA helicase (RecQ)
HUT14_RS20000	COG0561	phosphatase activity
HUT14_RS20020	COG1131	(ABC) transporter
HUT14_RS20035	COG0655	NAD(P)H dehydrogenase (quinone) activity
HUT14_RS20055	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HUT14_RS20085	COG3903	Transcriptional regulator
HUT14_RS20085	COG3629	intracellular signal transduction
HUT14_RS20090	COG0702	epimerase
HUT14_RS20095	COG1733	regulation of RNA biosynthetic process
HUT14_RS20100	COG1013	pyruvate-flavodoxin oxidoreductase activity
HUT14_RS20105	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HUT14_RS20105	COG0674	pyruvate-flavodoxin oxidoreductase activity
HUT14_RS20125	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT14_RS20130	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT14_RS20135	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT14_RS20140	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HUT14_RS20145	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT14_RS20150	COG0839	Belongs to the complex I subunit 6 family
HUT14_RS20155	COG0713	ATP synthesis coupled electron transport
HUT14_RS20165	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT14_RS20170	COG1007	ATP synthesis coupled electron transport
HUT14_RS20175	COG0501	Belongs to the peptidase M48B family
HUT14_RS20180	COG3304	Inner membrane component domain
HUT14_RS20195	COG2261	transglycosylase associated protein
HUT14_RS20200	COG1666	GTP binding
HUT14_RS20215	COG0702	epimerase
HUT14_RS20235	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HUT14_RS20240	COG2030	dehydratase
HUT14_RS20250	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HUT14_RS20255	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HUT14_RS20260	COG0436	Aminotransferase
HUT14_RS20275	COG0250	Participates in transcription elongation, termination and antitermination
HUT14_RS20280	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HUT14_RS20285	COG0081	regulation of translation
HUT14_RS20295	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HUT14_RS20300	COG0222	ribosome binding
HUT14_RS20305	COG0085	RNA polymerase activity
HUT14_RS20310	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HUT14_RS20320	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HUT14_RS20325	COG0049	tRNA binding
HUT14_RS20330	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HUT14_RS20335	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HUT14_RS20360	COG0667	Aldo Keto reductase
HUT14_RS20375	COG2197	response regulator
HUT14_RS20380	COG4585	Histidine kinase
HUT14_RS20385	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HUT14_RS20395	COG1028	Short-chain dehydrogenase reductase Sdr
HUT14_RS20430	COG0051	transcription antitermination factor activity, RNA binding
HUT14_RS20435	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HUT14_RS20440	COG0088	Forms part of the polypeptide exit tunnel
HUT14_RS20445	COG0089	rRNA binding
HUT14_RS20450	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HUT14_RS20455	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HUT14_RS20460	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HUT14_RS20465	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HUT14_RS20470	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HUT14_RS20475	COG0255	Belongs to the universal ribosomal protein uL29 family
HUT14_RS20480	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HUT14_RS20485	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HUT14_RS20490	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HUT14_RS20495	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HUT14_RS20500	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HUT14_RS20505	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HUT14_RS20510	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HUT14_RS20515	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HUT14_RS20520	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HUT14_RS20525	COG1841	ribosomal large subunit assembly
HUT14_RS20530	COG0200	Binds to the 23S rRNA
HUT14_RS20540	COG0563	adenylate kinase activity
HUT14_RS20550	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HUT14_RS20555	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HUT14_RS20560	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HUT14_RS20565	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HUT14_RS20570	COG0202	RNA polymerase activity
HUT14_RS20575	COG0203	ribosomal protein L17
HUT14_RS20580	COG0101	tRNA pseudouridine synthase activity
HUT14_RS20590	COG2843	Capsule synthesis protein
HUT14_RS20625	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HUT14_RS20630	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HUT14_RS20635	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HUT14_RS20645	COG1072	(Pantothenic acid kinase))
HUT14_RS20655	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HUT14_RS20660	COG0736	holo-[acyl-carrier-protein] synthase activity
HUT14_RS20665	COG1191	sigma factor activity
HUT14_RS20680	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HUT14_RS20690	COG0802	atpase or kinase
HUT14_RS20715	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HUT14_RS20735	COG1609	Transcriptional regulator
HUT14_RS20740	COG1316	TRANSCRIPTIONal
HUT14_RS20750	COG4941	Belongs to the sigma-70 factor family
HUT14_RS20760	COG0726	polysaccharide deacetylase
HUT14_RS20765	COG0726	polysaccharide deacetylase
HUT14_RS20770	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HUT14_RS20775	COG0459	protein refolding
HUT14_RS20830	COG4221	oxidoreductase activity
HUT14_RS20840	COG0583	DNA-binding transcription factor activity
HUT14_RS20855	COG1595	DNA-templated transcription, initiation
HUT14_RS20865	COG0516	GMP reductase activity
HUT14_RS20875	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HUT14_RS20895	COG0515	serine threonine protein kinase
HUT14_RS20900	COG0515	serine threonine protein kinase
HUT14_RS20905	COG0515	serine threonine protein kinase
HUT14_RS20910	COG1012	belongs to the aldehyde dehydrogenase family
HUT14_RS20935	COG0519	Catalyzes the synthesis of GMP from XMP
HUT14_RS20935	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HUT14_RS20975	COG2197	response regulator
HUT14_RS20995	COG0739	heme binding
HUT14_RS21005	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUT14_RS21005	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUT14_RS21020	COG0714	Associated with various cellular activities
HUT14_RS21025	COG2425	protein containing a von Willebrand factor type A (vWA) domain
HUT14_RS21030	COG3552	Protein containing von Willebrand factor type A (VWA) domain
HUT14_RS21040	COG0045	succinate-CoA ligase (ADP-forming) activity
HUT14_RS21070	COG0138	bifunctional purine biosynthesis protein purh
HUT14_RS21085	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HUT14_RS21100	COG0039	L-malate dehydrogenase activity
HUT14_RS21105	COG1012	belongs to the aldehyde dehydrogenase family
HUT14_RS21115	COG0517	IMP dehydrogenase activity
HUT14_RS21115	COG4175	Glycine betaine
HUT14_RS21120	COG4176	ABC-type proline glycine betaine transport system permease component
HUT14_RS21130	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUT14_RS21140	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT14_RS21150	COG0754	glutathionylspermidine amidase activity
HUT14_RS21155	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HUT14_RS21165	COG0180	Tryptophanyl-tRNA synthetase
HUT14_RS21185	COG0671	phosphoesterase, PA-phosphatase related
HUT14_RS21200	COG1295	ribonuclease BN
HUT14_RS21215	COG1408	metallophosphoesterase
HUT14_RS21220	COG1309	transcriptional regulator
HUT14_RS21240	COG1053	succinate dehydrogenase
HUT14_RS21250	COG2009	succinate dehydrogenase
HUT14_RS21260	COG3525	Glycosyl hydrolase, family 20, catalytic domain
HUT14_RS21315	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUT14_RS21315	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUT14_RS21345	COG1216	Glycosyl transferase, family 2
HUT14_RS21365	COG1216	Glycosyl transferase, family 2
HUT14_RS21380	COG2089	acid synthase
HUT14_RS21390	COG1473	amidohydrolase
HUT14_RS21390	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
HUT14_RS21395	COG1744	ABC transporter substrate-binding protein PnrA-like
HUT14_RS21400	COG1744	ABC transporter substrate-binding protein PnrA-like
HUT14_RS21450	COG2814	Major facilitator Superfamily
HUT14_RS21455	COG0583	DNA-binding transcription factor activity
HUT14_RS21465	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HUT14_RS21490	COG2205	protein histidine kinase activity
HUT14_RS21495	COG0745	RESPONSE REGULATOR receiver
HUT14_RS21500	COG1595	DNA-templated transcription, initiation
HUT14_RS21515	COG1012	belongs to the aldehyde dehydrogenase family
HUT14_RS21520	COG1012	belongs to the aldehyde dehydrogenase family
HUT14_RS21525	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HUT14_RS21535	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HUT14_RS21560	COG4770	biotin carboxylase activity
HUT14_RS21570	COG0424	maF-like protein
HUT14_RS21580	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUT14_RS21590	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
HUT14_RS21600	COG1024	Enoyl-CoA hydratase
HUT14_RS21610	COG2986	histidine ammonia-lyase
HUT14_RS21635	COG1136	(ABC) transporter
HUT14_RS21640	COG1404	Belongs to the peptidase S8 family
HUT14_RS21650	COG1064	alcohol dehydrogenase
HUT14_RS21660	COG0515	serine threonine protein kinase
HUT14_RS21660	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HUT14_RS21680	COG2255	four-way junction helicase activity
HUT14_RS21685	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HUT14_RS21700	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HUT14_RS21710	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HUT14_RS21745	COG1331	Highly conserved protein containing a thioredoxin domain
HUT14_RS21760	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
HUT14_RS21785	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT14_RS21900	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HUT14_RS21955	COG0436	Aminotransferase
HUT14_RS21970	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
HUT14_RS21985	COG1414	Transcriptional regulator
HUT14_RS21995	COG2610	gluconate transmembrane transporter activity
HUT14_RS22030	COG2894	cell division
HUT14_RS22065	COG2197	response regulator
HUT14_RS22155	COG2226	methyltransferase
HUT14_RS22160	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HUT14_RS22165	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
HUT14_RS22180	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUT14_RS22185	COG0450	alkyl hydroperoxide reductase
HUT14_RS22200	COG1136	(ABC) transporter
HUT14_RS22220	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HUT14_RS22235	COG0114	fumarate hydratase activity
HUT14_RS22265	COG2226	methyltransferase
HUT14_RS22280	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HUT14_RS22280	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HUT14_RS22305	COG0778	Nitroreductase
HUT14_RS22310	COG1722	exodeoxyribonuclease VII activity
HUT14_RS22315	COG1570	exodeoxyribonuclease VII activity
HUT14_RS22320	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HUT14_RS22325	COG1940	carbohydrate kinase activity
HUT14_RS22335	COG0012	GTP binding
HUT14_RS22365	COG1366	Belongs to the anti-sigma-factor antagonist family
HUT14_RS22370	COG1366	Belongs to the anti-sigma-factor antagonist family
HUT14_RS22375	COG2172	sigma factor antagonist activity
HUT14_RS22450	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HUT14_RS22455	COG1053	succinate dehydrogenase
HUT14_RS22490	COG0601	transmembrane transport
HUT14_RS22495	COG0444	Belongs to the ABC transporter superfamily
HUT14_RS22500	COG4608	Belongs to the ABC transporter superfamily
HUT14_RS22510	COG0601	transmembrane transport
HUT14_RS22520	COG0444	Belongs to the ABC transporter superfamily
HUT14_RS22525	COG4608	Belongs to the ABC transporter superfamily
HUT14_RS22540	COG0154	amidase activity
HUT14_RS22545	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HUT14_RS22560	COG0477	Major facilitator Superfamily
HUT14_RS22600	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUT14_RS22620	COG0519	Catalyzes the synthesis of GMP from XMP
HUT14_RS22625	COG1024	Enoyl-CoA hydratase
HUT14_RS22640	COG1595	DNA-templated transcription, initiation
HUT14_RS22655	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HUT14_RS22690	COG0598	Magnesium transport protein CorA
HUT14_RS22700	COG2814	Major facilitator Superfamily
HUT14_RS22710	COG0613	PHP domain protein
HUT14_RS22715	COG2095	MarC family integral membrane protein
HUT14_RS22725	COG1432	Conserved Protein
HUT14_RS22800	COG0596	Alpha beta hydrolase
HUT14_RS22825	COG0210	DNA helicase
HUT14_RS22830	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUT14_RS22835	COG2816	NAD+ diphosphatase activity
HUT14_RS22870	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HUT14_RS22925	COG3480	Lon protease (S16) C-terminal proteolytic domain
HUT14_RS22935	COG1615	UPF0182 protein
HUT14_RS22960	COG0753	catalase activity
HUT14_RS22970	COG0483	inositol monophosphate 1-phosphatase activity
HUT14_RS22980	COG2076	Multidrug Resistance protein
HUT14_RS22985	COG1162	GTPase activity
HUT14_RS22990	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HUT14_RS23000	COG2135	peptidase activity
HUT14_RS23010	COG1595	DNA-templated transcription, initiation
HUT14_RS23015	COG5662	AntiSigma factor
HUT14_RS23020	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HUT14_RS23020	COG2199	diguanylate cyclase activity
HUT14_RS23035	COG0242	peptide deformylase activity
HUT14_RS23045	COG2124	cytochrome p450
HUT14_RS23060	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HUT14_RS23085	COG2188	Transcriptional regulator
HUT14_RS23090	COG0363	glucosamine-6-phosphate deaminase activity
HUT14_RS23105	COG1597	lipid kinase activity
HUT14_RS23115	COG1191	sigma factor activity
HUT14_RS23150	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUT14_RS23160	COG0456	acetyltransferase
HUT14_RS23170	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HUT14_RS23220	COG4106	trans-aconitate 2-methyltransferase activity
HUT14_RS23225	COG1126	abc transporter atp-binding protein
HUT14_RS23240	COG0281	malic enzyme
HUT14_RS23245	COG0604	alcohol dehydrogenase
HUT14_RS23275	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUT14_RS23275	COG0567	Dehydrogenase, E1 component
HUT14_RS23280	COG2205	protein histidine kinase activity
HUT14_RS23285	COG0745	RESPONSE REGULATOR receiver
HUT14_RS23290	COG0275	rRNA processing
HUT14_RS23295	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HUT14_RS23365	COG0768	penicillin binding
HUT14_RS23370	COG0772	Belongs to the SEDS family
HUT14_RS23390	COG1793	dna ligase
HUT14_RS23390	COG3285	dna ligase
HUT14_RS23395	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HUT14_RS23415	COG1595	DNA-templated transcription, initiation
HUT14_RS23430	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
HUT14_RS23465	COG1959	2 iron, 2 sulfur cluster binding
HUT14_RS23465	COG1295	ribonuclease BN
HUT14_RS23470	COG1366	Belongs to the anti-sigma-factor antagonist family
HUT14_RS23620	COG0018	arginyl-trna synthetase
HUT14_RS23625	COG0019	diaminopimelate decarboxylase activity
HUT14_RS23630	COG0460	homoserine dehydrogenase
HUT14_RS23635	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HUT14_RS23640	COG0083	homoserine kinase activity
HUT14_RS23655	COG0254	rRNA binding
HUT14_RS23660	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HUT14_RS23665	COG2890	protein-(glutamine-N5) methyltransferase activity
HUT14_RS23675	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HUT14_RS23680	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HUT14_RS23685	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HUT14_RS23700	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HUT14_RS23705	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HUT14_RS23710	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HUT14_RS23715	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HUT14_RS23720	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HUT14_RS23725	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HUT14_RS23730	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HUT14_RS23745	COG2197	response regulator
HUT14_RS23750	COG4585	Histidine kinase
HUT14_RS23775	COG1309	transcriptional regulator
HUT14_RS23785	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUT14_RS23800	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
HUT14_RS23835	COG1131	(ABC) transporter
HUT14_RS23855	COG0183	Belongs to the thiolase family
HUT14_RS23870	COG0745	RESPONSE REGULATOR receiver
HUT14_RS23930	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUT14_RS23930	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUT14_RS23970	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HUT14_RS23975	COG0280	phosphate acetyltransferase
HUT14_RS23975	COG0857	belongs to the CobB CobQ family
HUT14_RS23980	COG0205	6-phosphofructokinase activity
HUT14_RS23990	COG0395	ABC-type sugar transport system, permease component
HUT14_RS23995	COG1175	transmembrane transport
HUT14_RS24000	COG1653	transport
HUT14_RS24005	COG4565	transcriptional regulatory protein
HUT14_RS24010	COG3290	protein histidine kinase activity
HUT14_RS24015	COG1301	dicarboxylic acid transport
HUT14_RS24020	COG0789	Transcriptional regulator
HUT14_RS24035	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HUT14_RS24040	COG3281	Trehalose synthase
HUT14_RS24050	COG0366	Alpha amylase catalytic
HUT14_RS24055	COG0058	SHG alpha-glucan phosphorylase activity
HUT14_RS24075	COG1132	(ABC) transporter
HUT14_RS24080	COG1132	(ABC) transporter
HUT14_RS24085	COG1132	(ABC) transporter
HUT14_RS24090	COG1132	(ABC) transporter
HUT14_RS24095	COG1131	(ABC) transporter
HUT14_RS24105	COG4585	Histidine kinase
HUT14_RS24110	COG2197	response regulator
HUT14_RS24165	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HUT14_RS24195	COG0464	growth
HUT14_RS24205	COG1674	ftsk spoiiie
HUT14_RS24270	COG1760	l-serine dehydratase
HUT14_RS24275	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HUT14_RS24280	COG0509	glycine decarboxylation via glycine cleavage system
HUT14_RS24285	COG0404	The glycine cleavage system catalyzes the degradation of glycine
HUT14_RS24305	COG0747	negative chemotaxis
HUT14_RS24320	COG0444	Belongs to the ABC transporter superfamily
HUT14_RS24325	COG4608	Belongs to the ABC transporter superfamily
HUT14_RS24330	COG2860	membrane
HUT14_RS24340	COG1309	transcriptional regulator
HUT14_RS24370	COG0482	sulfurtransferase activity
HUT14_RS24390	COG1611	Belongs to the LOG family
HUT14_RS24395	COG4221	oxidoreductase activity
HUT14_RS24405	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HUT14_RS24415	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HUT14_RS24420	COG0154	amidase activity
HUT14_RS24430	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HUT14_RS24435	COG2226	methyltransferase
HUT14_RS24445	COG2409	Drug exporters of the RND superfamily
HUT14_RS24450	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUT14_RS24460	COG2197	response regulator
HUT14_RS24470	COG2133	pyrroloquinoline quinone binding
HUT14_RS24475	COG0667	Aldo Keto reductase
HUT14_RS24485	COG5001	Diguanylate cyclase
HUT14_RS24485	COG3300	MHYT domain
HUT14_RS24495	COG0440	acetolactate synthase activity
HUT14_RS24500	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HUT14_RS24505	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HUT14_RS24510	COG0477	Major facilitator Superfamily
HUT14_RS24520	COG2508	Transcriptional regulator
HUT14_RS24525	COG0506	proline dehydrogenase activity
HUT14_RS24530	COG1012	belongs to the aldehyde dehydrogenase family
HUT14_RS24535	COG0473	3-isopropylmalate dehydrogenase activity
HUT14_RS24540	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HUT14_RS24545	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HUT14_RS24560	COG1032	radical SAM domain protein
HUT14_RS24565	COG0300	oxidoreductase activity
HUT14_RS24570	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUT14_RS24590	COG2018	Roadblock/LC7 domain
HUT14_RS24610	COG2018	Roadblock/LC7 domain
HUT14_RS24615	COG5002	protein histidine kinase activity
HUT14_RS24625	COG0179	Fumarylacetoacetate (FAA) hydrolase
HUT14_RS24630	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HUT14_RS24665	COG0789	Transcriptional regulator
HUT14_RS24675	COG1414	Transcriptional regulator
HUT14_RS24680	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HUT14_RS24685	COG0066	3-isopropylmalate dehydratase activity
HUT14_RS24695	COG0776	regulation of translation
HUT14_RS24705	COG1920	GTP binding
HUT14_RS24715	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
HUT14_RS24720	COG1181	Belongs to the D-alanine--D-alanine ligase family
HUT14_RS24740	COG0351	phosphomethylpyrimidine kinase
HUT14_RS24745	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HUT14_RS24750	COG1461	Dihydroxyacetone kinase
HUT14_RS24760	COG0742	ribosomal rna small subunit methyltransferase
HUT14_RS24765	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HUT14_RS24775	COG1399	metal-binding, possibly nucleic acid-binding protein
HUT14_RS24780	COG0333	Belongs to the bacterial ribosomal protein bL32 family
HUT14_RS24785	COG0571	ribonuclease III activity
HUT14_RS24790	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HUT14_RS24795	COG1733	regulation of RNA biosynthetic process
HUT14_RS24830	COG2340	Cysteine-rich secretory protein family
HUT14_RS24835	COG1254	Belongs to the acylphosphatase family
HUT14_RS24845	COG1196	nuclear chromosome segregation
HUT14_RS24850	COG0477	Major facilitator Superfamily
HUT14_RS24880	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
HUT14_RS24900	COG0228	four-way junction DNA binding
HUT14_RS24905	COG1837	Belongs to the UPF0109 family
HUT14_RS24910	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HUT14_RS24915	COG0336	Belongs to the RNA methyltransferase TrmD family
HUT14_RS24920	COG0335	large ribosomal subunit rRNA binding
HUT14_RS24935	COG0681	Belongs to the peptidase S26 family
HUT14_RS24940	COG0681	Belongs to the peptidase S26 family
HUT14_RS24945	COG0494	nUDIX hydrolase
HUT14_RS24955	COG0792	nuclease activity
HUT14_RS24970	COG1191	sigma factor activity
HUT14_RS24980	COG4942	peptidase
HUT14_RS24985	COG0052	Belongs to the universal ribosomal protein uS2 family
HUT14_RS24990	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HUT14_RS24995	COG0528	UMP kinase activity
HUT14_RS25000	COG0233	cytoplasmic translational termination
HUT14_RS25005	COG0575	Belongs to the CDS family
HUT14_RS25015	COG0820	rRNA (adenine-C2-)-methyltransferase activity
HUT14_RS25025	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HUT14_RS25030	COG3842	ATPase activity
HUT14_RS25060	COG1136	(ABC) transporter
HUT14_RS25065	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HUT14_RS25075	COG1012	belongs to the aldehyde dehydrogenase family
HUT14_RS25090	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HUT14_RS25120	COG3842	ATPase activity
HUT14_RS25130	COG1177	transmembrane transport
HUT14_RS25135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUT14_RS25155	COG2508	Transcriptional regulator
HUT14_RS25160	COG1012	belongs to the aldehyde dehydrogenase family
HUT14_RS25175	COG4209	transmembrane transport
HUT14_RS25180	COG0395	ABC-type sugar transport system, permease component
HUT14_RS25205	COG2197	response regulator
HUT14_RS25210	COG4585	Histidine kinase
HUT14_RS25220	COG1136	(ABC) transporter
HUT14_RS25220	COG4591	ABC-type transport system involved in lipoprotein release permease component
HUT14_RS25230	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HUT14_RS25235	COG0750	zinc metalloprotease
HUT14_RS25240	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HUT14_RS25255	COG0442	prolyl-tRNA aminoacylation
HUT14_RS25275	COG0779	Required for maturation of 30S ribosomal subunits
HUT14_RS25290	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HUT14_RS25300	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HUT14_RS25305	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HUT14_RS25320	COG4608	Belongs to the ABC transporter superfamily
HUT14_RS25325	COG0444	Belongs to the ABC transporter superfamily
HUT14_RS25335	COG0601	transmembrane transport
HUT14_RS25340	COG0747	negative chemotaxis
HUT14_RS25345	COG0455	bacterial-type flagellum organization
HUT14_RS25355	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HUT14_RS25360	COG1185	polyribonucleotide nucleotidyltransferase activity
HUT14_RS25365	COG0612	Peptidase, M16
HUT14_RS25370	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
HUT14_RS25390	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUT14_RS25395	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HUT14_RS25425	COG2770	Histidine kinase
HUT14_RS25425	COG2208	phosphoserine phosphatase activity
HUT14_RS25430	COG2205	protein histidine kinase activity
HUT14_RS25430	COG0784	Response regulator, receiver
HUT14_RS25440	COG1674	ftsk spoiiie
HUT14_RS25450	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HUT14_RS25460	COG1546	Belongs to the CinA family
HUT14_RS25460	COG1058	Belongs to the CinA family
HUT14_RS25465	COG1396	sequence-specific DNA binding
HUT14_RS25470	COG0783	Belongs to the Dps family
HUT14_RS25480	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HUT14_RS25485	COG1201	RNA secondary structure unwinding
HUT14_RS25515	COG0628	permease
HUT14_RS25520	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HUT14_RS25565	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT14_RS25570	COG0765	amino acid transport
HUT14_RS25575	COG0765	amino acid transport
HUT14_RS25580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUT14_RS25585	COG1126	abc transporter atp-binding protein
HUT14_RS25590	COG0745	RESPONSE REGULATOR receiver
HUT14_RS25595	COG2205	protein histidine kinase activity
HUT14_RS25600	COG2358	TRAP transporter, solute receptor (TAXI family
HUT14_RS25615	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HUT14_RS25635	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HUT14_RS25645	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HUT14_RS25650	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HUT14_RS25655	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HUT14_RS25685	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HUT14_RS25690	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HUT14_RS25695	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HUT14_RS25730	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HUT14_RS25765	COG1802	Transcriptional regulator
HUT14_RS25790	COG0187	DNA topoisomerase II activity
HUT14_RS25800	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUT14_RS25805	COG4565	transcriptional regulatory protein
HUT14_RS25810	COG3290	protein histidine kinase activity
HUT14_RS25835	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HUT14_RS25840	COG0612	Peptidase, M16
HUT14_RS25855	COG1802	Transcriptional regulator
HUT14_RS25860	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUT14_RS25865	COG1042	CoA-binding domain protein
HUT14_RS25865	COG0045	succinate-CoA ligase (ADP-forming) activity
HUT14_RS25865	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUT14_RS25880	COG1435	thymidine kinase activity
HUT14_RS25900	COG3864	Putative metallopeptidase domain
HUT14_RS25905	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
HUT14_RS25975	COG0745	RESPONSE REGULATOR receiver
HUT14_RS25980	COG2205	protein histidine kinase activity
HUT14_RS26005	COG0756	dUTP diphosphatase activity
HUT14_RS26015	COG1136	(ABC) transporter
HUT14_RS26015	COG4591	ABC-type transport system involved in lipoprotein release permease component
HUT14_RS26045	COG0569	domain protein
HUT14_RS26050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUT14_RS26055	COG0531	amino acid
HUT14_RS26060	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HUT14_RS26105	COG0659	secondary active sulfate transmembrane transporter activity
HUT14_RS26110	COG0789	Transcriptional regulator
HUT14_RS26120	COG0640	Transcriptional regulator
HUT14_RS26125	COG2072	flavoprotein involved in K transport
HUT14_RS26130	COG0798	PFAM Bile acid sodium symporter
HUT14_RS26140	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HUT14_RS26145	COG0596	Alpha beta hydrolase
HUT14_RS26170	COG1960	acyl-CoA dehydrogenase activity
HUT14_RS26175	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUT14_RS26180	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HUT14_RS26185	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HUT14_RS26190	COG0583	DNA-binding transcription factor activity
HUT14_RS26195	COG0183	Belongs to the thiolase family
HUT14_RS26200	COG0477	Major facilitator Superfamily
HUT14_RS26215	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HUT14_RS26220	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
HUT14_RS26230	COG1216	Glycosyl transferase, family 2
HUT14_RS26240	COG4310	Domain of unknown function (DUF2172)
HUT14_RS26255	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HUT14_RS26290	COG0367	asparagine synthase
HUT14_RS26310	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HUT14_RS26325	COG4172	Belongs to the ABC transporter superfamily
HUT14_RS26330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUT14_RS26335	COG0601	transmembrane transport
HUT14_RS26340	COG4166	transmembrane transport
HUT14_RS26355	COG4948	Mandelate Racemase Muconate Lactonizing
HUT14_RS26360	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HUT14_RS26370	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HUT14_RS26380	COG2186	Transcriptional regulator
HUT14_RS26385	COG1013	pyruvate-flavodoxin oxidoreductase activity
HUT14_RS26390	COG0674	pyruvate-flavodoxin oxidoreductase activity
HUT14_RS26390	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HUT14_RS26395	COG0175	sulfate reduction
HUT14_RS26415	COG1116	anion transmembrane transporter activity
HUT14_RS26440	COG2197	response regulator
HUT14_RS26445	COG4585	Histidine kinase
HUT14_RS26475	COG1960	acyl-CoA dehydrogenase activity
HUT14_RS26485	COG2070	2-Nitropropane dioxygenase
HUT14_RS26485	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HUT14_RS26495	COG3321	synthase
HUT14_RS26495	COG0604	alcohol dehydrogenase
HUT14_RS26495	COG0604	alcohol dehydrogenase
HUT14_RS26495	COG3321	synthase
HUT14_RS26510	COG4566	intracellular signal transduction
HUT14_RS26515	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
HUT14_RS26530	COG1028	Short-chain dehydrogenase reductase Sdr
HUT14_RS26535	COG0402	S-adenosylhomocysteine deaminase activity
HUT14_RS26545	COG1021	2,3-dihydroxybenzoate-AMP ligase
HUT14_RS26555	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
HUT14_RS26575	COG1942	4-Oxalocrotonate Tautomerase
HUT14_RS26620	COG1349	DNA-binding transcription factor activity
HUT14_RS26625	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HUT14_RS26635	COG0667	Aldo Keto reductase
HUT14_RS26650	COG1914	H( )-stimulated, divalent metal cation uptake system
HUT14_RS26655	COG0738	Major facilitator superfamily
HUT14_RS26670	COG2188	Transcriptional regulator
HUT14_RS26675	COG2182	Extracellular solute-binding protein
HUT14_RS26680	COG1175	transmembrane transport
HUT14_RS26685	COG0395	ABC-type sugar transport system, permease component
HUT14_RS26690	COG1472	Belongs to the glycosyl hydrolase 3 family
HUT14_RS26700	COG1799	cell septum assembly
HUT14_RS26730	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HUT14_RS26740	COG2255	four-way junction helicase activity
HUT14_RS26750	COG0475	glutathione-regulated potassium exporter activity
HUT14_RS26760	COG2235	arginine
HUT14_RS26765	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HUT14_RS26775	COG1024	Enoyl-CoA hydratase
HUT14_RS26830	COG2755	lipolytic protein G-D-S-L family
HUT14_RS26835	COG1122	ATPase activity
HUT14_RS26845	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
HUT14_RS26850	COG0310	cobalt ion transport
HUT14_RS26860	COG0601	transmembrane transport
HUT14_RS26865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUT14_RS26870	COG0444	Belongs to the ABC transporter superfamily
HUT14_RS26890	COG1653	transport
HUT14_RS26905	COG0515	serine threonine protein kinase
HUT14_RS26965	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUT14_RS27000	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HUT14_RS27010	COG4257	antibiotic catabolic process
HUT14_RS27015	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HUT14_RS27040	COG1653	transport
HUT14_RS27045	COG1175	transmembrane transport
HUT14_RS27050	COG0395	ABC-type sugar transport system, permease component
HUT14_RS27055	COG1940	carbohydrate kinase activity
HUT14_RS27060	COG4213	ABC transporter substrate-binding protein
HUT14_RS27070	COG4214	carbohydrate transport
HUT14_RS27075	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HUT14_RS27080	COG0531	amino acid
HUT14_RS27095	COG1316	TRANSCRIPTIONal
HUT14_RS27100	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HUT14_RS27120	COG1024	Enoyl-CoA hydratase
HUT14_RS27120	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUT14_RS27125	COG0183	Belongs to the thiolase family
HUT14_RS27130	COG1609	Transcriptional regulator
HUT14_RS27135	COG3250	beta-galactosidase activity
HUT14_RS27145	COG1175	transmembrane transport
HUT14_RS27155	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
HUT14_RS27170	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HUT14_RS27205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT14_RS27210	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HUT14_RS27235	COG1132	(ABC) transporter
HUT14_RS27250	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT14_RS27275	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT14_RS27280	COG2197	response regulator
HUT14_RS27285	COG4585	Histidine kinase
HUT14_RS27305	COG0318	PFAM AMP-dependent synthetase and ligase
HUT14_RS27325	COG0446	pyridine nucleotide-disulphide oxidoreductase
HUT14_RS27355	COG3220	belongs to the UPF0276 family
HUT14_RS27380	COG0723	plastoquinol--plastocyanin reductase activity
HUT14_RS27395	COG0330	HflC and HflK could
HUT14_RS27400	COG0659	secondary active sulfate transmembrane transporter activity
HUT14_RS27425	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HUT14_RS27430	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HUT14_RS27460	COG0745	RESPONSE REGULATOR receiver
HUT14_RS27465	COG5002	protein histidine kinase activity
HUT14_RS27475	COG2205	protein histidine kinase activity
HUT14_RS27480	COG0745	RESPONSE REGULATOR receiver
HUT14_RS27500	COG2186	Transcriptional regulator
HUT14_RS27510	COG2376	Dihydroxyacetone kinase
HUT14_RS27515	COG0698	ribose 5-phosphate isomerase
HUT14_RS27520	COG0149	triose-phosphate isomerase activity
HUT14_RS27525	COG1082	Xylose isomerase domain protein TIM barrel
HUT14_RS27530	COG2084	Dehydrogenase
HUT14_RS27540	COG1174	glycine betaine transport
HUT14_RS27545	COG1174	glycine betaine transport
HUT14_RS27585	COG1309	transcriptional regulator
HUT14_RS27605	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HUT14_RS27690	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUT14_RS27695	COG1116	anion transmembrane transporter activity
HUT14_RS27715	COG0529	Catalyzes the synthesis of activated sulfate
HUT14_RS27720	COG0175	sulfate reduction
HUT14_RS27750	COG1960	acyl-CoA dehydrogenase activity
HUT14_RS27765	COG1917	Cupin 2, conserved barrel domain protein
HUT14_RS27765	COG4977	sequence-specific DNA binding
HUT14_RS27810	COG0789	Transcriptional regulator
HUT14_RS27835	COG2040	homocysteine
HUT14_RS27845	COG0477	Major facilitator Superfamily
HUT14_RS27880	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HUT14_RS27890	COG2755	lipolytic protein G-D-S-L family
HUT14_RS27945	COG0277	FAD linked oxidase domain protein
HUT14_RS27955	COG5297	Belongs to the glycosyl hydrolase family 6
HUT14_RS27960	COG1162	GTPase activity
HUT14_RS27985	COG0028	Belongs to the TPP enzyme family
HUT14_RS28015	COG1802	Transcriptional regulator
HUT14_RS28025	COG3835	regulator
HUT14_RS28040	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HUT14_RS28070	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HUT14_RS28080	COG0438	transferase activity, transferring glycosyl groups
HUT14_RS28090	COG1216	Glycosyl transferase, family 2
HUT14_RS28125	COG2197	response regulator
HUT14_RS28130	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUT14_RS28135	COG0318	PFAM AMP-dependent synthetase and ligase
HUT14_RS28140	COG3960	tartronate-semialdehyde synthase activity
HUT14_RS28155	COG2084	Dehydrogenase
HUT14_RS28160	COG3622	Belongs to the hyi family
HUT14_RS28180	COG2351	hydroxyisourate hydrolase activity
HUT14_RS28255	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUT14_RS28320	COG1414	Transcriptional regulator
HUT14_RS28325	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HUT14_RS28330	COG4266	Belongs to the allantoicase family
HUT14_RS28335	COG1028	Short-chain dehydrogenase reductase Sdr
HUT14_RS28355	COG2197	response regulator
HUT14_RS28370	COG2188	Transcriptional regulator
HUT14_RS28385	COG1129	ABC transporter
HUT14_RS28390	COG1940	carbohydrate kinase activity
HUT14_RS28400	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HUT14_RS28465	COG0142	geranyltranstransferase activity
HUT14_RS28470	COG3046	protein related to deoxyribodipyrimidine photolyase
HUT14_RS28480	COG0702	epimerase
HUT14_RS28485	COG1028	Short-chain dehydrogenase reductase Sdr
HUT14_RS28490	COG1278	Cold shock
HUT14_RS28495	COG0513	Belongs to the DEAD box helicase family
HUT14_RS28505	COG1278	Cold shock
HUT14_RS28510	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HUT14_RS28515	COG1115	amino acid carrier protein
HUT14_RS28535	COG1278	Cold shock
HUT14_RS28560	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUT14_RS28565	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
HUT14_RS28585	COG0405	Gamma-glutamyltransferase
HUT14_RS28590	COG0542	response to heat
HUT14_RS28615	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HUT14_RS28620	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HUT14_RS28630	COG1953	Uracil, thiamine, allantoin
HUT14_RS28650	COG4608	Belongs to the ABC transporter superfamily
HUT14_RS28655	COG0444	Belongs to the ABC transporter superfamily
HUT14_RS28665	COG4166	transmembrane transport
HUT14_RS28675	COG3458	cephalosporin-C deacetylase activity
HUT14_RS28685	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUT14_RS28695	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HUT14_RS28705	COG0483	inositol monophosphate 1-phosphatase activity
HUT14_RS28715	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HUT14_RS28725	COG0640	Transcriptional regulator
HUT14_RS28745	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HUT14_RS28755	COG1929	Belongs to the glycerate kinase type-1 family
HUT14_RS28770	COG0688	phosphatidylethanolamine metabolic process
HUT14_RS28775	COG1960	acyl-CoA dehydrogenase activity
HUT14_RS28785	COG2301	Belongs to the HpcH HpaI aldolase family
HUT14_RS28790	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUT14_RS28790	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUT14_RS28795	COG0604	alcohol dehydrogenase
HUT14_RS28805	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUT14_RS28820	COG0596	Alpha beta hydrolase
HUT14_RS28850	COG2362	D-Aminopeptidase
HUT14_RS28855	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUT14_RS28860	COG4946	Tricorn protease homolog
HUT14_RS28860	COG0823	Involved in the tonB-independent uptake of proteins
HUT14_RS28860	COG1506	peptidase
HUT14_RS28865	COG1619	proteins homologs of microcin C7 resistance protein MccF
HUT14_RS28890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT14_RS28905	COG1793	dna ligase
HUT14_RS28905	COG3285	dna ligase
HUT14_RS28965	COG0488	(ABC) transporter
HUT14_RS28980	COG0693	protein deglycase activity
HUT14_RS28985	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
HUT14_RS29055	COG0443	Heat shock 70 kDa protein
HUT14_RS29075	COG2154	pterin-4-alpha-carbinolamine dehydratase
HUT14_RS29085	COG3401	FG-GAP repeat protein
HUT14_RS29100	COG5297	Belongs to the glycosyl hydrolase family 6
HUT14_RS29100	COG4733	cellulase activity
HUT14_RS29105	COG5297	Belongs to the glycosyl hydrolase family 6
HUT14_RS29115	COG4221	oxidoreductase activity
HUT14_RS29120	COG0656	L-ascorbic acid biosynthetic process
HUT14_RS29140	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HUT14_RS29155	COG3383	formate dehydrogenase (NAD+) activity
HUT14_RS29160	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HUT14_RS29175	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUT14_RS29185	COG1940	carbohydrate kinase activity
HUT14_RS29190	COG1129	ABC transporter
HUT14_RS29195	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUT14_RS29200	COG1879	ABC-type sugar transport system periplasmic component
HUT14_RS29205	COG0673	inositol 2-dehydrogenase activity
HUT14_RS29260	COG2223	nitrite transmembrane transporter activity
HUT14_RS29270	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUT14_RS29280	COG0045	succinate-CoA ligase (ADP-forming) activity
HUT14_RS29290	COG1012	belongs to the aldehyde dehydrogenase family
HUT14_RS29305	COG0210	DNA helicase
HUT14_RS29320	COG0515	serine threonine protein kinase
HUT14_RS29350	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HUT14_RS29405	COG0477	Major facilitator Superfamily
HUT14_RS29410	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HUT14_RS29420	COG2182	Extracellular solute-binding protein
HUT14_RS29425	COG1175	transmembrane transport
HUT14_RS29430	COG0395	ABC-type sugar transport system, permease component
HUT14_RS29435	COG2723	6-phospho-beta-galactosidase activity
HUT14_RS29470	COG0714	Associated with various cellular activities
HUT14_RS29475	COG3552	Protein containing von Willebrand factor type A (VWA) domain
HUT14_RS29505	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
HUT14_RS29505	COG5479	isomerase activity
HUT14_RS29640	COG0297	glycogen (starch) synthase activity
HUT14_RS29660	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUT14_RS29670	COG3467	pyridoxamine 5'-phosphate
HUT14_RS29675	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HUT14_RS29680	COG0477	Major facilitator Superfamily
HUT14_RS29685	COG1309	transcriptional regulator
HUT14_RS29690	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HUT14_RS29700	COG0406	alpha-ribazole phosphatase activity
HUT14_RS29705	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
HUT14_RS29710	COG0166	Belongs to the GPI family
HUT14_RS29730	COG2409	Drug exporters of the RND superfamily
HUT14_RS29735	COG2197	response regulator
HUT14_RS29740	COG4585	Histidine kinase
HUT14_RS29745	COG1486	melibiose metabolic process
HUT14_RS29785	COG1653	transport
HUT14_RS29790	COG1175	transmembrane transport
HUT14_RS29795	COG0395	ABC-type sugar transport system, permease component
HUT14_RS29800	COG0366	Alpha amylase catalytic
HUT14_RS29810	COG0515	serine threonine protein kinase
HUT14_RS29820	COG1132	(ABC) transporter
HUT14_RS29825	COG1132	(ABC) transporter
HUT14_RS29830	COG2197	response regulator
HUT14_RS29840	COG3511	phospholipase C
HUT14_RS29865	COG1672	PFAM Archaeal ATPase
HUT14_RS29865	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
HUT14_RS29870	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUT14_RS29880	COG3485	protocatechuate 3,4-dioxygenase
HUT14_RS29885	COG3485	protocatechuate 3,4-dioxygenase
HUT14_RS29915	COG1793	dna ligase
HUT14_RS29965	COG0488	(ABC) transporter
HUT14_RS29995	COG1515	deoxyribonuclease V activity
HUT14_RS30000	COG3268	Saccharopine dehydrogenase
HUT14_RS30010	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUT14_RS30015	COG0183	Belongs to the thiolase family
HUT14_RS30020	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUT14_RS30020	COG1024	Enoyl-CoA hydratase
HUT14_RS30035	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HUT14_RS30050	COG0488	(ABC) transporter
HUT14_RS30060	COG2183	response to ionizing radiation
HUT14_RS30065	COG1024	Enoyl-CoA hydratase
HUT14_RS30080	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
HUT14_RS30125	COG1134	teichoic acid transport
HUT14_RS30130	COG1562	ergosterol biosynthetic process
HUT14_RS30140	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HUT14_RS30150	COG1657	PFAM Prenyltransferase squalene oxidase
HUT14_RS30165	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HUT14_RS30170	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HUT14_RS30205	COG2755	lipolytic protein G-D-S-L family
HUT14_RS30245	COG1063	alcohol dehydrogenase
HUT14_RS30250	COG0156	8-amino-7-oxononanoate synthase activity
HUT14_RS30255	COG0583	DNA-binding transcription factor activity
HUT14_RS30260	COG1028	Short-chain dehydrogenase reductase Sdr
HUT14_RS30280	COG2072	flavoprotein involved in K transport
HUT14_RS30285	COG1960	acyl-CoA dehydrogenase activity
HUT14_RS30340	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUT14_RS30400	COG0395	ABC-type sugar transport system, permease component
HUT14_RS30405	COG1175	transmembrane transport
HUT14_RS30430	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HUT14_RS30435	COG1993	acr, cog1993
HUT14_RS30440	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HUT14_RS30450	COG2186	Transcriptional regulator
HUT14_RS30480	COG3458	cephalosporin-C deacetylase activity
HUT14_RS30495	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HUT14_RS30505	COG2890	protein-(glutamine-N5) methyltransferase activity
HUT14_RS30520	COG1902	pentaerythritol trinitrate reductase activity
HUT14_RS30520	COG0446	pyridine nucleotide-disulphide oxidoreductase
HUT14_RS30550	COG1461	Dihydroxyacetone kinase
HUT14_RS30555	COG2376	Dihydroxyacetone kinase
HUT14_RS30560	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUT14_RS30570	COG0446	pyridine nucleotide-disulphide oxidoreductase
HUT14_RS30575	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUT14_RS30580	COG3938	Belongs to the proline racemase family
HUT14_RS30585	COG1802	Transcriptional regulator
HUT14_RS30590	COG2239	Acts as a magnesium transporter
HUT14_RS30620	COG0589	response to stress
HUT14_RS30630	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HUT14_RS30635	COG0569	domain protein
HUT14_RS30650	COG0071	Belongs to the small heat shock protein (HSP20) family
HUT14_RS30680	COG1063	alcohol dehydrogenase
HUT14_RS30690	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUT14_RS30695	COG0022	dehydrogenase e1 component
HUT14_RS30695	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUT14_RS30700	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HUT14_RS30705	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUT14_RS30755	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HUT14_RS30755	COG0574	Belongs to the PEP-utilizing enzyme family
HUT14_RS30760	COG4191	Histidine kinase
HUT14_RS30780	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HUT14_RS30795	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HUT14_RS30825	COG1140	nitrate reductase beta subunit
HUT14_RS30845	COG0517	IMP dehydrogenase activity
HUT14_RS30845	COG0516	GMP reductase activity
HUT14_RS30855	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HUT14_RS30940	COG0515	serine threonine protein kinase
HUT14_RS30950	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HUT14_RS31055	COG0346	lactoylglutathione lyase activity
HUT14_RS31060	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HUT14_RS31070	COG0583	DNA-binding transcription factor activity
HUT14_RS31075	COG0667	Aldo Keto reductase
HUT14_RS31110	COG1191	sigma factor activity
HUT14_RS31115	COG1396	sequence-specific DNA binding
HUT14_RS31120	COG0740	serine-type endopeptidase activity
HUT14_RS31125	COG0740	serine-type endopeptidase activity
HUT14_RS31140	COG0328	RNA-DNA hybrid ribonuclease activity
HUT14_RS31145	COG0667	Aldo Keto reductase
HUT14_RS31175	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HUT14_RS31175	COG0515	serine threonine protein kinase
HUT14_RS31180	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HUT14_RS31185	COG2340	Cysteine-rich secretory protein family
HUT14_RS31215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUT14_RS31265	COG0477	Major facilitator Superfamily
HUT14_RS31305	COG1252	NADH dehydrogenase
HUT14_RS31320	COG2172	sigma factor antagonist activity
HUT14_RS31325	COG1366	Belongs to the anti-sigma-factor antagonist family
HUT14_RS31330	COG1366	Belongs to the anti-sigma-factor antagonist family
HUT14_RS31345	COG2205	protein histidine kinase activity
HUT14_RS31345	COG5002	protein histidine kinase activity
HUT14_RS31345	COG0784	Response regulator, receiver
HUT14_RS31375	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
HUT14_RS31380	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HUT14_RS31385	COG3281	Trehalose synthase
HUT14_RS31395	COG0366	Alpha amylase catalytic
HUT14_RS31435	COG0181	hydroxymethylbilane synthase activity
HUT14_RS31445	COG3285	dna ligase
HUT14_RS31445	COG1793	dna ligase
HUT14_RS31470	COG1793	dna ligase
HUT14_RS31470	COG3285	dna ligase
HUT14_RS31475	COG0656	L-ascorbic acid biosynthetic process
HUT14_RS31495	COG0009	L-threonylcarbamoyladenylate synthase
HUT14_RS31505	COG2267	carboxylic ester hydrolase activity
HUT14_RS31510	COG0753	catalase activity
HUT14_RS31535	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
HUT14_RS31535	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
HUT14_RS31540	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
HUT14_RS31545	COG0438	transferase activity, transferring glycosyl groups
HUT14_RS31555	COG2192	nodulation
HUT14_RS31560	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUT14_RS31565	COG2124	cytochrome p450
HUT14_RS31600	COG3540	Alkaline phosphatase
HUT14_RS31630	COG1063	alcohol dehydrogenase
HUT14_RS31640	COG0659	secondary active sulfate transmembrane transporter activity
HUT14_RS31660	COG2264	protein methyltransferase activity
HUT14_RS31670	COG1295	ribonuclease BN
HUT14_RS31675	COG0456	acetyltransferase
HUT14_RS31685	COG2409	Drug exporters of the RND superfamily
HUT14_RS31720	COG1175	transmembrane transport
HUT14_RS31725	COG0395	ABC-type sugar transport system, permease component
HUT14_RS31750	COG0667	Aldo Keto reductase
HUT14_RS31825	COG0714	Associated with various cellular activities
HUT14_RS31850	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HUT14_RS31855	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HUT14_RS31915	COG2259	Doxx family
HUT14_RS31930	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HUT14_RS31935	COG2409	Drug exporters of the RND superfamily
HUT14_RS31940	COG1846	Transcriptional regulator
HUT14_RS31975	COG0596	Alpha beta hydrolase
HUT14_RS31975	COG2945	thiolester hydrolase activity
HUT14_RS31980	COG1733	regulation of RNA biosynthetic process
HUT14_RS31990	COG0656	L-ascorbic acid biosynthetic process
HUT14_RS32035	COG1595	DNA-templated transcription, initiation
HUT14_RS32040	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT14_RS32045	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT14_RS32055	COG0604	alcohol dehydrogenase
HUT14_RS32070	COG0318	PFAM AMP-dependent synthetase and ligase
HUT14_RS32080	COG3396	Phenylacetate-CoA oxygenase
HUT14_RS32090	COG3396	Phenylacetate-CoA oxygenase
HUT14_RS32095	COG2151	metal-sulfur cluster biosynthetic enzyme
HUT14_RS32100	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUT14_RS32105	COG1028	Short-chain dehydrogenase reductase Sdr
HUT14_RS32110	COG3483	tryptophan 2,3-dioxygenase activity
HUT14_RS32120	COG3844	kynureninase activity
HUT14_RS32185	COG1451	nucleotide metabolic process
HUT14_RS32190	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HUT14_RS32230	COG0159	tryptophan synthase activity
HUT14_RS32320	COG0515	serine threonine protein kinase
HUT14_RS32320	COG2815	serine threonine protein kinase
HUT14_RS32465	COG0738	Major facilitator superfamily
HUT14_RS32590	COG0154	amidase activity
HUT14_RS32605	COG2264	protein methyltransferase activity
HUT14_RS32610	COG0494	nUDIX hydrolase
HUT14_RS32635	COG0494	nUDIX hydrolase
HUT14_RS32645	COG1051	belongs to the nudix hydrolase family
HUT14_RS32665	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HUT14_RS32680	COG0302	gtp cyclohydrolase
HUT14_RS32685	COG0602	queuosine metabolic process
HUT14_RS32690	COG0720	synthase
HUT14_RS32745	COG3387	PFAM Glycoside hydrolase 15-related
HUT14_RS32775	COG1324	tolerance protein
HUT14_RS32795	COG1012	belongs to the aldehyde dehydrogenase family
HUT14_RS32810	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT14_RS32815	COG1120	ATPase activity
HUT14_RS32825	COG0738	Major facilitator superfamily
HUT14_RS32830	COG1595	DNA-templated transcription, initiation
HUT14_RS32840	COG1120	ATPase activity
HUT14_RS32845	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HUT14_RS32855	COG0803	Belongs to the bacterial solute-binding protein 9 family
HUT14_RS32930	COG2045	Belongs to the ComB family
HUT14_RS32945	COG2378	regulation of single-species biofilm formation
HUT14_RS32970	COG1028	Short-chain dehydrogenase reductase Sdr
HUT14_RS32995	COG1309	transcriptional regulator
HUT14_RS33015	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUT14_RS33020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT14_RS33030	COG0183	Belongs to the thiolase family
HUT14_RS33035	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUT14_RS33035	COG1024	Enoyl-CoA hydratase
HUT14_RS33040	COG1022	Amp-dependent synthetase and ligase
HUT14_RS33045	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HUT14_RS33060	COG1891	lyase activity
HUT14_RS33080	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HUT14_RS33090	COG0583	DNA-binding transcription factor activity
HUT14_RS33105	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HUT14_RS33110	COG0456	acetyltransferase
HUT14_RS33140	COG2755	lipolytic protein G-D-S-L family
HUT14_RS33170	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HUT14_RS33170	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HUT14_RS33180	COG0477	Major facilitator Superfamily
HUT14_RS33195	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HUT14_RS33230	COG0514	ATP-dependent DNA helicase (RecQ)
HUT14_RS33240	COG0515	serine threonine protein kinase
HUT14_RS33240	COG2815	serine threonine protein kinase
HUT14_RS33255	COG1309	transcriptional regulator
HUT14_RS33260	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUT14_RS33275	COG0531	amino acid
HUT14_RS33290	COG0596	Alpha beta hydrolase
HUT14_RS33315	COG1733	regulation of RNA biosynthetic process
HUT14_RS33325	COG2188	Transcriptional regulator
HUT14_RS33330	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HUT14_RS33335	COG1869	D-ribose catabolic process
HUT14_RS33340	COG1129	ABC transporter
HUT14_RS33350	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUT14_RS33355	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUT14_RS33420	COG4608	Belongs to the ABC transporter superfamily
HUT14_RS33425	COG0444	Belongs to the ABC transporter superfamily
HUT14_RS33435	COG0601	transmembrane transport
HUT14_RS33440	COG4166	transmembrane transport
HUT14_RS33445	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HUT14_RS33450	COG4948	Mandelate Racemase Muconate Lactonizing
HUT14_RS33455	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HUT14_RS33460	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUT14_RS33480	COG0667	Aldo Keto reductase
HUT14_RS33510	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUT14_RS33520	COG0254	rRNA binding
HUT14_RS33525	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HUT14_RS33530	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HUT14_RS33535	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HUT14_RS33540	COG0640	Transcriptional regulator
HUT14_RS33545	COG0346	lactoylglutathione lyase activity
HUT14_RS33650	COG0395	ABC-type sugar transport system, permease component
HUT14_RS33675	COG0667	Aldo Keto reductase
HUT14_RS33695	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HUT14_RS33695	COG0515	serine threonine protein kinase
HUT14_RS33745	COG2124	cytochrome p450
HUT14_RS33755	COG3321	synthase
HUT14_RS33755	COG1028	Short-chain dehydrogenase reductase Sdr
HUT14_RS33755	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUT14_RS33755	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUT14_RS33755	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT14_RS33760	COG3321	synthase
HUT14_RS33760	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUT14_RS33760	COG0300	oxidoreductase activity
HUT14_RS33760	COG4221	oxidoreductase activity
HUT14_RS33765	COG3321	synthase
HUT14_RS33765	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUT14_RS33765	COG0300	oxidoreductase activity
HUT14_RS33765	COG4221	oxidoreductase activity
HUT14_RS33770	COG4221	oxidoreductase activity
HUT14_RS33770	COG3321	synthase
HUT14_RS33770	COG0300	oxidoreductase activity
HUT14_RS33770	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUT14_RS33775	COG0300	oxidoreductase activity
HUT14_RS33775	COG3321	synthase
HUT14_RS33775	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUT14_RS33775	COG4221	oxidoreductase activity
HUT14_RS33780	COG2070	2-Nitropropane dioxygenase
HUT14_RS33780	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HUT14_RS33785	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HUT14_RS33790	COG3425	synthase
HUT14_RS33795	COG1024	Enoyl-CoA hydratase
HUT14_RS33800	COG1024	Enoyl-CoA hydratase
HUT14_RS33805	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUT14_RS33810	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUT14_RS33815	COG3321	synthase
HUT14_RS33820	COG0300	oxidoreductase activity
HUT14_RS33835	COG2814	Major facilitator Superfamily
HUT14_RS33920	COG3547	Transposase (IS116 IS110 IS902 family)
HUT14_RS34050	COG2815	serine threonine protein kinase
HUT14_RS34050	COG0515	serine threonine protein kinase