locus-tag	class	description
HUT19_RS00180	COG0791	NLP P60 protein
HUT19_RS00180	COG3883	PFAM NLP P60 protein
HUT19_RS00495	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HUT19_RS00530	COG3335	DDE superfamily endonuclease
HUT19_RS00580	COG0667	Aldo Keto reductase
HUT19_RS00585	COG3321	synthase
HUT19_RS00585	COG1028	Short-chain dehydrogenase reductase Sdr
HUT19_RS00585	COG0604	alcohol dehydrogenase
HUT19_RS00690	COG3335	DDE superfamily endonuclease
HUT19_RS00780	COG0477	Major facilitator Superfamily
HUT19_RS00795	COG1028	Short-chain dehydrogenase reductase Sdr
HUT19_RS00800	COG2175	clavaminate synthase activity
HUT19_RS00810	COG3251	PFAM MbtH domain protein
HUT19_RS00815	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT19_RS00835	COG0583	DNA-binding transcription factor activity
HUT19_RS00850	COG1028	Short-chain dehydrogenase reductase Sdr
HUT19_RS00875	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT19_RS00880	COG1960	acyl-CoA dehydrogenase activity
HUT19_RS00885	COG0475	glutathione-regulated potassium exporter activity
HUT19_RS00950	COG1309	transcriptional regulator
HUT19_RS00960	COG1129	ABC transporter
HUT19_RS00960	COG0842	Transport permease protein
HUT19_RS01000	COG1028	Short-chain dehydrogenase reductase Sdr
HUT19_RS01065	COG0477	Major facilitator Superfamily
HUT19_RS01070	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
HUT19_RS01100	COG0071	Belongs to the small heat shock protein (HSP20) family
HUT19_RS01110	COG2267	carboxylic ester hydrolase activity
HUT19_RS01115	COG1024	Enoyl-CoA hydratase
HUT19_RS01120	COG1024	Enoyl-CoA hydratase
HUT19_RS01125	COG1024	Enoyl-CoA hydratase
HUT19_RS01130	COG3424	synthase
HUT19_RS01165	COG0577	efflux transmembrane transporter activity
HUT19_RS01165	COG1136	(ABC) transporter
HUT19_RS01170	COG1136	(ABC) transporter
HUT19_RS01170	COG0577	efflux transmembrane transporter activity
HUT19_RS01175	COG3773	Cell wall hydrolase
HUT19_RS01175	COG3409	Peptidoglycan-binding domain 1 protein
HUT19_RS01180	COG0745	RESPONSE REGULATOR receiver
HUT19_RS01185	COG2205	protein histidine kinase activity
HUT19_RS01220	COG1132	(ABC) transporter
HUT19_RS01265	COG2197	response regulator
HUT19_RS01270	COG3851	Histidine kinase
HUT19_RS01275	COG3227	Zinc metalloprotease (Elastase)
HUT19_RS01290	COG3457	Alanine racemase
HUT19_RS01305	COG1940	carbohydrate kinase activity
HUT19_RS01310	COG1940	carbohydrate kinase activity
HUT19_RS01310	COG1846	Transcriptional regulator
HUT19_RS01335	COG0583	DNA-binding transcription factor activity
HUT19_RS01345	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUT19_RS01345	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
HUT19_RS01350	COG2188	Transcriptional regulator
HUT19_RS01370	COG1278	Cold shock
HUT19_RS01375	COG0583	DNA-binding transcription factor activity
HUT19_RS01405	COG1042	CoA-binding domain protein
HUT19_RS01405	COG0045	succinate-CoA ligase (ADP-forming) activity
HUT19_RS01405	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUT19_RS01410	COG2326	polyphosphate kinase activity
HUT19_RS01435	COG0517	IMP dehydrogenase activity
HUT19_RS01435	COG0516	GMP reductase activity
HUT19_RS01470	COG0569	domain protein
HUT19_RS01475	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HUT19_RS01480	COG3383	formate dehydrogenase (NAD+) activity
HUT19_RS01555	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
HUT19_RS01555	COG0617	tRNA 3'-terminal CCA addition
HUT19_RS01555	COG0517	IMP dehydrogenase activity
HUT19_RS01575	COG1960	acyl-CoA dehydrogenase activity
HUT19_RS01580	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUT19_RS01595	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUT19_RS01600	COG0583	DNA-binding transcription factor activity
HUT19_RS01655	COG0022	dehydrogenase e1 component
HUT19_RS01655	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUT19_RS01660	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HUT19_RS01665	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUT19_RS01680	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HUT19_RS01700	COG0596	Alpha beta hydrolase
HUT19_RS01710	COG4977	sequence-specific DNA binding
HUT19_RS01725	COG3835	regulator
HUT19_RS01750	COG1012	belongs to the aldehyde dehydrogenase family
HUT19_RS01760	COG0318	PFAM AMP-dependent synthetase and ligase
HUT19_RS01785	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUT19_RS01805	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HUT19_RS01805	COG2010	Cytochrome c
HUT19_RS01815	COG1309	transcriptional regulator
HUT19_RS01820	COG0154	amidase activity
HUT19_RS01830	COG2378	regulation of single-species biofilm formation
HUT19_RS01860	COG2135	peptidase activity
HUT19_RS01880	COG0247	lactate metabolic process
HUT19_RS01880	COG0277	FAD linked oxidase domain protein
HUT19_RS01885	COG0028	Belongs to the TPP enzyme family
HUT19_RS01890	COG4948	Mandelate Racemase Muconate Lactonizing
HUT19_RS01905	COG2770	Histidine kinase
HUT19_RS01905	COG2208	phosphoserine phosphatase activity
HUT19_RS01920	COG2890	protein-(glutamine-N5) methyltransferase activity
HUT19_RS01945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT19_RS01955	COG1846	Transcriptional regulator
HUT19_RS01975	COG0574	Belongs to the PEP-utilizing enzyme family
HUT19_RS01975	COG3848	Pyruvate phosphate dikinase
HUT19_RS01980	COG0789	Transcriptional regulator
HUT19_RS02020	COG3631	Ketosteroid isomerase-related protein
HUT19_RS02025	COG0702	epimerase
HUT19_RS02035	COG0477	Major facilitator Superfamily
HUT19_RS02055	COG2814	Major facilitator Superfamily
HUT19_RS02075	COG2249	NAD(P)H dehydrogenase (quinone) activity
HUT19_RS02080	COG0640	Transcriptional regulator
HUT19_RS02095	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HUT19_RS02105	COG0154	amidase activity
HUT19_RS02125	COG1021	2,3-dihydroxybenzoate-AMP ligase
HUT19_RS02150	COG2226	methyltransferase
HUT19_RS02155	COG2226	methyltransferase
HUT19_RS02160	COG0475	glutathione-regulated potassium exporter activity
HUT19_RS02180	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HUT19_RS02220	COG2267	carboxylic ester hydrolase activity
HUT19_RS02230	COG1404	Belongs to the peptidase S8 family
HUT19_RS02270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT19_RS02275	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HUT19_RS02280	COG1119	ATPase activity
HUT19_RS02290	COG4948	Mandelate Racemase Muconate Lactonizing
HUT19_RS02310	COG0531	amino acid
HUT19_RS02345	COG1028	Short-chain dehydrogenase reductase Sdr
HUT19_RS02405	COG1733	regulation of RNA biosynthetic process
HUT19_RS02505	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HUT19_RS02565	COG0346	lactoylglutathione lyase activity
HUT19_RS02580	COG0488	(ABC) transporter
HUT19_RS02595	COG0745	RESPONSE REGULATOR receiver
HUT19_RS02605	COG1012	belongs to the aldehyde dehydrogenase family
HUT19_RS02610	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HUT19_RS02615	COG1028	Short-chain dehydrogenase reductase Sdr
HUT19_RS02625	COG1024	Enoyl-CoA hydratase
HUT19_RS02630	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUT19_RS02640	COG0477	Major facilitator Superfamily
HUT19_RS02645	COG1396	sequence-specific DNA binding
HUT19_RS02660	COG4977	sequence-specific DNA binding
HUT19_RS02805	COG1609	Transcriptional regulator
HUT19_RS02815	COG0395	ABC-type sugar transport system, permease component
HUT19_RS02825	COG1653	transport
HUT19_RS02855	COG0477	Major facilitator Superfamily
HUT19_RS02900	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HUT19_RS02905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT19_RS02965	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT19_RS02970	COG0778	Nitroreductase
HUT19_RS03005	COG4106	trans-aconitate 2-methyltransferase activity
HUT19_RS03020	COG0723	plastoquinol--plastocyanin reductase activity
HUT19_RS03020	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUT19_RS03105	COG0028	Belongs to the TPP enzyme family
HUT19_RS03135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT19_RS03140	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HUT19_RS03145	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HUT19_RS03160	COG1733	regulation of RNA biosynthetic process
HUT19_RS03175	COG1280	lysine exporter protein (LysE YggA)
HUT19_RS03180	COG0328	RNA-DNA hybrid ribonuclease activity
HUT19_RS03220	COG2223	nitrite transmembrane transporter activity
HUT19_RS03225	COG2207	Transcriptional regulator
HUT19_RS03260	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUT19_RS03265	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HUT19_RS03285	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HUT19_RS03290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT19_RS03295	COG1120	ATPase activity
HUT19_RS03305	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HUT19_RS03310	COG1181	Belongs to the D-alanine--D-alanine ligase family
HUT19_RS03325	COG0596	Alpha beta hydrolase
HUT19_RS03330	COG3903	Transcriptional regulator
HUT19_RS03330	COG3629	intracellular signal transduction
HUT19_RS03345	COG3291	Pkd domain containing protein
HUT19_RS03345	COG3525	Glycosyl hydrolase, family 20, catalytic domain
HUT19_RS03360	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HUT19_RS03365	COG1960	acyl-CoA dehydrogenase activity
HUT19_RS03375	COG1522	sequence-specific DNA binding
HUT19_RS03390	COG1309	transcriptional regulator
HUT19_RS03435	COG3290	protein histidine kinase activity
HUT19_RS03440	COG1012	belongs to the aldehyde dehydrogenase family
HUT19_RS03460	COG0531	amino acid
HUT19_RS03470	COG0247	lactate metabolic process
HUT19_RS03470	COG0277	FAD linked oxidase domain protein
HUT19_RS03475	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HUT19_RS03515	COG2837	iron assimilation
HUT19_RS03520	COG0604	alcohol dehydrogenase
HUT19_RS03520	COG1028	Short-chain dehydrogenase reductase Sdr
HUT19_RS03520	COG3321	synthase
HUT19_RS03525	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUT19_RS03535	COG1834	amidinotransferase
HUT19_RS03540	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HUT19_RS03595	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
HUT19_RS03615	COG2226	methyltransferase
HUT19_RS03620	COG0443	Heat shock 70 kDa protein
HUT19_RS03635	COG2309	aminopeptidase activity
HUT19_RS03640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT19_RS03645	COG0477	Major facilitator Superfamily
HUT19_RS03670	COG1335	isochorismatase
HUT19_RS03675	COG0596	Alpha beta hydrolase
HUT19_RS03680	COG1846	Transcriptional regulator
HUT19_RS03700	COG1472	Belongs to the glycosyl hydrolase 3 family
HUT19_RS03720	COG3387	PFAM Glycoside hydrolase 15-related
HUT19_RS03730	COG3960	tartronate-semialdehyde synthase activity
HUT19_RS03750	COG1796	DNA polymerase
HUT19_RS03750	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
HUT19_RS03770	COG3254	rhamnose metabolic process
HUT19_RS03775	COG0673	inositol 2-dehydrogenase activity
HUT19_RS03780	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
HUT19_RS03785	COG1349	DNA-binding transcription factor activity
HUT19_RS03790	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HUT19_RS03795	COG0191	fructose-bisphosphate aldolase activity
HUT19_RS03805	COG0477	Major facilitator Superfamily
HUT19_RS03835	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HUT19_RS03855	COG0745	RESPONSE REGULATOR receiver
HUT19_RS03860	COG2205	protein histidine kinase activity
HUT19_RS03865	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HUT19_RS03875	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HUT19_RS03890	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HUT19_RS03920	COG2159	amidohydrolase
HUT19_RS03935	COG0590	tRNA wobble adenosine to inosine editing
HUT19_RS03940	COG3224	Antibiotic biosynthesis monooxygenase
HUT19_RS03960	COG0183	Belongs to the thiolase family
HUT19_RS03965	COG1309	transcriptional regulator
HUT19_RS03975	COG1960	acyl-CoA dehydrogenase activity
HUT19_RS03980	COG1960	acyl-CoA dehydrogenase activity
HUT19_RS03995	COG1960	acyl-CoA dehydrogenase activity
HUT19_RS04000	COG1024	Enoyl-CoA hydratase
HUT19_RS04030	COG3360	Dodecin
HUT19_RS04040	COG3958	Transketolase
HUT19_RS04045	COG1252	NADH dehydrogenase
HUT19_RS04055	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HUT19_RS04075	COG0667	Aldo Keto reductase
HUT19_RS04085	COG2197	response regulator
HUT19_RS04090	COG4585	Histidine kinase
HUT19_RS04150	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HUT19_RS04210	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
HUT19_RS04230	COG0110	maltose O-acetyltransferase activity
HUT19_RS04255	COG2124	cytochrome p450
HUT19_RS04285	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUT19_RS04310	COG0671	phosphoesterase, PA-phosphatase related
HUT19_RS04325	COG0477	Major facilitator Superfamily
HUT19_RS04330	COG0745	RESPONSE REGULATOR receiver
HUT19_RS04335	COG2205	protein histidine kinase activity
HUT19_RS04375	COG2205	protein histidine kinase activity
HUT19_RS04395	COG0174	glutamine synthetase
HUT19_RS04405	COG0300	oxidoreductase activity
HUT19_RS04410	COG1064	alcohol dehydrogenase
HUT19_RS04430	COG0386	Belongs to the glutathione peroxidase family
HUT19_RS04445	COG3842	ATPase activity
HUT19_RS04450	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HUT19_RS04455	COG1176	ABC-type spermidine putrescine transport system, permease component I
HUT19_RS04460	COG1177	transmembrane transport
HUT19_RS04530	COG0395	ABC-type sugar transport system, permease component
HUT19_RS04535	COG1175	transmembrane transport
HUT19_RS04540	COG1653	transport
HUT19_RS04545	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
HUT19_RS04545	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
HUT19_RS04555	COG1486	melibiose metabolic process
HUT19_RS04560	COG1349	DNA-binding transcription factor activity
HUT19_RS04580	COG1063	alcohol dehydrogenase
HUT19_RS04585	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT19_RS04600	COG0514	ATP-dependent DNA helicase (RecQ)
HUT19_RS04640	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HUT19_RS04650	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
HUT19_RS04665	COG0589	response to stress
HUT19_RS04675	COG1063	alcohol dehydrogenase
HUT19_RS04730	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HUT19_RS04750	COG0242	peptide deformylase activity
HUT19_RS04770	COG1741	Belongs to the pirin family
HUT19_RS04800	COG1595	DNA-templated transcription, initiation
HUT19_RS04805	COG3903	Transcriptional regulator
HUT19_RS04805	COG3629	intracellular signal transduction
HUT19_RS04850	COG0546	phosphoglycolate phosphatase activity
HUT19_RS04865	COG2356	endonuclease I
HUT19_RS04890	COG1191	sigma factor activity
HUT19_RS04900	COG1793	dna ligase
HUT19_RS04975	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HUT19_RS04980	COG1960	acyl-CoA dehydrogenase activity
HUT19_RS04990	COG0242	peptide deformylase activity
HUT19_RS05000	COG3442	glutamine amidotransferase
HUT19_RS05005	COG0205	6-phosphofructokinase activity
HUT19_RS05060	COG2234	aminopeptidase activity
HUT19_RS05060	COG4935	Belongs to the peptidase S8 family
HUT19_RS05070	COG0740	serine-type endopeptidase activity
HUT19_RS05080	COG0791	NLP P60 protein
HUT19_RS05080	COG0741	lytic transglycosylase activity
HUT19_RS05120	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HUT19_RS05125	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HUT19_RS05130	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HUT19_RS05135	COG2226	methyltransferase
HUT19_RS05150	COG1136	(ABC) transporter
HUT19_RS05150	COG0577	efflux transmembrane transporter activity
HUT19_RS05190	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HUT19_RS05195	COG3663	DNA glycosylase
HUT19_RS05205	COG1940	carbohydrate kinase activity
HUT19_RS05210	COG2188	Transcriptional regulator
HUT19_RS05215	COG1028	Short-chain dehydrogenase reductase Sdr
HUT19_RS05220	COG1595	DNA-templated transcription, initiation
HUT19_RS05225	COG2267	carboxylic ester hydrolase activity
HUT19_RS05245	COG0626	cystathionine gamma-synthase activity
HUT19_RS05260	COG0419	ATPase involved in DNA repair
HUT19_RS05265	COG0420	3'-5' exonuclease activity
HUT19_RS05270	COG0745	RESPONSE REGULATOR receiver
HUT19_RS05275	COG2205	protein histidine kinase activity
HUT19_RS05285	COG1739	Uncharacterized protein family UPF0029
HUT19_RS05290	COG1832	CoA-binding protein
HUT19_RS05350	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HUT19_RS05370	COG1968	undecaprenyl-diphosphatase activity
HUT19_RS05380	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HUT19_RS05390	COG4977	sequence-specific DNA binding
HUT19_RS05445	COG3046	protein related to deoxyribodipyrimidine photolyase
HUT19_RS05475	COG1027	Aspartate ammonia-lyase
HUT19_RS05485	COG1113	amino acid transport
HUT19_RS05490	COG2186	Transcriptional regulator
HUT19_RS05500	COG0815	Transfers the fatty acyl group on membrane lipoproteins
HUT19_RS05505	COG0673	inositol 2-dehydrogenase activity
HUT19_RS05530	COG2378	regulation of single-species biofilm formation
HUT19_RS05545	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HUT19_RS05595	COG0697	spore germination
HUT19_RS05625	COG0697	spore germination
HUT19_RS05650	COG1695	Transcriptional regulator
HUT19_RS05680	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HUT19_RS05680	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HUT19_RS05690	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HUT19_RS05710	COG1716	ATPase activity
HUT19_RS05730	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HUT19_RS05760	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HUT19_RS05775	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT19_RS05780	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUT19_RS05795	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HUT19_RS05805	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUT19_RS05810	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HUT19_RS05815	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HUT19_RS05830	COG2018	Roadblock/LC7 domain
HUT19_RS05850	COG2146	nitrite reductase [NAD(P)H] activity
HUT19_RS05870	COG4638	Rieske (2fe-2S)
HUT19_RS05875	COG1012	belongs to the aldehyde dehydrogenase family
HUT19_RS05880	COG0531	amino acid
HUT19_RS05915	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HUT19_RS05935	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
HUT19_RS05940	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HUT19_RS05945	COG1984	allophanate hydrolase subunit 2
HUT19_RS05970	COG0438	transferase activity, transferring glycosyl groups
HUT19_RS05975	COG0438	transferase activity, transferring glycosyl groups
HUT19_RS06015	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUT19_RS06050	COG1024	Enoyl-CoA hydratase
HUT19_RS06070	COG0596	Alpha beta hydrolase
HUT19_RS06080	COG2070	2-Nitropropane dioxygenase
HUT19_RS06090	COG0515	serine threonine protein kinase
HUT19_RS06100	COG1309	transcriptional regulator
HUT19_RS06135	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HUT19_RS06140	COG0251	oxidation-reduction process
HUT19_RS06145	COG0477	Major facilitator Superfamily
HUT19_RS06155	COG0028	Belongs to the TPP enzyme family
HUT19_RS06160	COG0477	Major facilitator Superfamily
HUT19_RS06165	COG0804	urea catabolic process
HUT19_RS06170	COG0831	urea catabolic process
HUT19_RS06170	COG0832	Belongs to the urease beta subunit family
HUT19_RS06180	COG1960	acyl-CoA dehydrogenase activity
HUT19_RS06190	COG2376	Dihydroxyacetone kinase
HUT19_RS06195	COG1461	Dihydroxyacetone kinase
HUT19_RS06200	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HUT19_RS06200	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUT19_RS06200	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
HUT19_RS06215	COG2124	cytochrome p450
HUT19_RS06235	COG1028	Short-chain dehydrogenase reductase Sdr
HUT19_RS06240	COG0494	nUDIX hydrolase
HUT19_RS06255	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HUT19_RS06260	COG1215	transferase activity, transferring glycosyl groups
HUT19_RS06315	COG1349	DNA-binding transcription factor activity
HUT19_RS06395	COG1940	carbohydrate kinase activity
HUT19_RS06425	COG2197	response regulator
HUT19_RS06430	COG4585	Histidine kinase
HUT19_RS06435	COG0445	tRNA wobble uridine modification
HUT19_RS06440	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUT19_RS06450	COG3833	ABC-type maltose transport systems, permease component
HUT19_RS06455	COG1175	transmembrane transport
HUT19_RS06465	COG3345	alpha-galactosidase
HUT19_RS06470	COG0515	serine threonine protein kinase
HUT19_RS06470	COG2815	serine threonine protein kinase
HUT19_RS06475	COG1940	carbohydrate kinase activity
HUT19_RS06510	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HUT19_RS06550	COG0584	glycerophosphoryl diester phosphodiesterase
HUT19_RS06585	COG0671	phosphoesterase, PA-phosphatase related
HUT19_RS06600	COG1011	Hydrolase
HUT19_RS06605	COG1309	transcriptional regulator
HUT19_RS06625	COG2233	PERMEase
HUT19_RS06665	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT19_RS06675	COG4865	methylaspartate mutase activity
HUT19_RS06695	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HUT19_RS06705	COG1960	acyl-CoA dehydrogenase activity
HUT19_RS06710	COG0662	Cupin 2, conserved barrel domain protein
HUT19_RS06730	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HUT19_RS06735	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HUT19_RS06765	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT19_RS06780	COG1902	pentaerythritol trinitrate reductase activity
HUT19_RS06790	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HUT19_RS06810	COG2706	6-phosphogluconolactonase activity
HUT19_RS06835	COG1968	undecaprenyl-diphosphatase activity
HUT19_RS06855	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HUT19_RS06870	COG0432	Pfam Uncharacterised protein family UPF0047
HUT19_RS06885	COG1609	Transcriptional regulator
HUT19_RS06890	COG0247	lactate metabolic process
HUT19_RS06895	COG1139	Iron-sulfur cluster binding protein
HUT19_RS06900	COG1556	Lactate utilization protein
HUT19_RS06955	COG2186	Transcriptional regulator
HUT19_RS06960	COG2364	Membrane
HUT19_RS06990	COG2111	Na H antiporter
HUT19_RS06995	COG1006	Multisubunit Na H antiporter MnhC subunit
HUT19_RS07000	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT19_RS07010	COG0463	Glycosyl transferase, family 2
HUT19_RS07035	COG1960	acyl-CoA dehydrogenase activity
HUT19_RS07080	COG1012	belongs to the aldehyde dehydrogenase family
HUT19_RS07085	COG0009	L-threonylcarbamoyladenylate synthase
HUT19_RS07105	COG5001	Diguanylate cyclase
HUT19_RS07115	COG3835	regulator
HUT19_RS07125	COG0572	uridine kinase
HUT19_RS07150	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
HUT19_RS07155	COG0140	phosphoribosyl-ATP diphosphatase activity
HUT19_RS07160	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
HUT19_RS07165	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUT19_RS07165	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUT19_RS07180	COG1940	carbohydrate kinase activity
HUT19_RS07180	COG1846	Transcriptional regulator
HUT19_RS07185	COG0738	Major facilitator superfamily
HUT19_RS07205	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HUT19_RS07215	COG0531	amino acid
HUT19_RS07235	COG2390	Transcriptional regulator
HUT19_RS07240	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HUT19_RS07260	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HUT19_RS07275	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HUT19_RS07285	COG1758	RNA polymerase activity
HUT19_RS07300	COG0284	orotidine-5'-phosphate decarboxylase activity
HUT19_RS07305	COG0167	dihydroorotate dehydrogenase activity
HUT19_RS07310	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HUT19_RS07315	COG0505	Belongs to the CarA family
HUT19_RS07325	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HUT19_RS07330	COG0540	Belongs to the ATCase OTCase family
HUT19_RS07335	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HUT19_RS07345	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HUT19_RS07350	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HUT19_RS07365	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HUT19_RS07370	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HUT19_RS07375	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HUT19_RS07380	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HUT19_RS07390	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HUT19_RS07395	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HUT19_RS07410	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HUT19_RS07430	COG1131	(ABC) transporter
HUT19_RS07440	COG4585	Histidine kinase
HUT19_RS07445	COG2197	response regulator
HUT19_RS07450	COG0124	histidyl-tRNA synthetase
HUT19_RS07465	COG1196	nuclear chromosome segregation
HUT19_RS07470	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HUT19_RS07475	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HUT19_RS07480	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HUT19_RS07485	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HUT19_RS07495	COG2255	four-way junction helicase activity
HUT19_RS07500	COG0632	four-way junction helicase activity
HUT19_RS07505	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HUT19_RS07510	COG0217	transcriptional regulatory protein
HUT19_RS07515	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HUT19_RS07520	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HUT19_RS07530	COG0438	transferase activity, transferring glycosyl groups
HUT19_RS07535	COG1560	Kdo2-lipid A biosynthetic process
HUT19_RS07540	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HUT19_RS07560	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HUT19_RS07575	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HUT19_RS07740	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HUT19_RS07800	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HUT19_RS07800	COG1648	precorrin-2 dehydrogenase activity
HUT19_RS07805	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
HUT19_RS07820	COG1464	Belongs to the NlpA lipoprotein family
HUT19_RS07825	COG1464	Belongs to the NlpA lipoprotein family
HUT19_RS07830	COG2011	ABC-type metal ion transport system permease component
HUT19_RS07835	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HUT19_RS07870	COG0318	PFAM AMP-dependent synthetase and ligase
HUT19_RS07870	COG0204	Acyl-transferase
HUT19_RS07885	COG0165	Argininosuccinate lyase
HUT19_RS07890	COG0137	argininosuccinate synthase activity
HUT19_RS07905	COG1028	Short-chain dehydrogenase reductase Sdr
HUT19_RS07910	COG1309	transcriptional regulator
HUT19_RS07915	COG1028	Short-chain dehydrogenase reductase Sdr
HUT19_RS07920	COG3835	regulator
HUT19_RS07980	COG1477	protein flavinylation
HUT19_RS07995	COG1438	arginine binding
HUT19_RS08000	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HUT19_RS08010	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HUT19_RS08015	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HUT19_RS08020	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HUT19_RS08060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT19_RS08065	COG0697	spore germination
HUT19_RS08075	COG1649	PFAM Uncharacterised BCR, COG1649
HUT19_RS08085	COG1285	pathogenesis
HUT19_RS08095	COG0494	nUDIX hydrolase
HUT19_RS08110	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HUT19_RS08110	COG0072	phenylalanine-tRNA ligase activity
HUT19_RS08115	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HUT19_RS08120	COG5002	protein histidine kinase activity
HUT19_RS08125	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUT19_RS08130	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HUT19_RS08135	COG0291	Belongs to the bacterial ribosomal protein bL35 family
HUT19_RS08140	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HUT19_RS08150	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HUT19_RS08165	COG1404	Belongs to the peptidase S8 family
HUT19_RS08190	COG1012	belongs to the aldehyde dehydrogenase family
HUT19_RS08205	COG0531	amino acid
HUT19_RS08210	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HUT19_RS08240	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HUT19_RS08255	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUT19_RS08280	COG2755	lipolytic protein G-D-S-L family
HUT19_RS08305	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HUT19_RS08310	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HUT19_RS08325	COG1657	PFAM Prenyltransferase squalene oxidase
HUT19_RS08335	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HUT19_RS08345	COG1562	ergosterol biosynthetic process
HUT19_RS08360	COG2826	transposase and inactivated derivatives, IS30 family
HUT19_RS08365	COG1134	teichoic acid transport
HUT19_RS08410	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
HUT19_RS08435	COG2183	response to ionizing radiation
HUT19_RS08445	COG0488	(ABC) transporter
HUT19_RS08470	COG2936	dipeptidyl-peptidase activity
HUT19_RS08485	COG3250	beta-galactosidase activity
HUT19_RS08495	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUT19_RS08495	COG1024	Enoyl-CoA hydratase
HUT19_RS08500	COG0183	Belongs to the thiolase family
HUT19_RS08505	COG1960	acyl-CoA dehydrogenase activity
HUT19_RS08510	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUT19_RS08525	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUT19_RS08535	COG1515	deoxyribonuclease V activity
HUT19_RS08595	COG1012	belongs to the aldehyde dehydrogenase family
HUT19_RS08600	COG0531	amino acid
HUT19_RS08620	COG0431	NADPH-dependent FMN reductase
HUT19_RS08630	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT19_RS08670	COG0477	Major facilitator Superfamily
HUT19_RS08685	COG1012	belongs to the aldehyde dehydrogenase family
HUT19_RS08695	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HUT19_RS08715	COG2226	methyltransferase
HUT19_RS08720	COG1022	Amp-dependent synthetase and ligase
HUT19_RS08730	COG0656	L-ascorbic acid biosynthetic process
HUT19_RS08745	COG1595	DNA-templated transcription, initiation
HUT19_RS08760	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HUT19_RS08765	COG2154	pterin-4-alpha-carbinolamine dehydratase
HUT19_RS08790	COG0531	amino acid
HUT19_RS08805	COG0701	Predicted permease
HUT19_RS08820	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HUT19_RS08855	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HUT19_RS08865	COG4214	carbohydrate transport
HUT19_RS08875	COG4213	ABC transporter substrate-binding protein
HUT19_RS08920	COG1295	ribonuclease BN
HUT19_RS08930	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
HUT19_RS08955	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUT19_RS08960	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUT19_RS08980	COG0439	Biotin carboxylase
HUT19_RS09035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT19_RS09040	COG0028	Belongs to the TPP enzyme family
HUT19_RS09045	COG4948	Mandelate Racemase Muconate Lactonizing
HUT19_RS09050	COG0693	protein deglycase activity
HUT19_RS09075	COG2226	methyltransferase
HUT19_RS09090	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUT19_RS09105	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUT19_RS09110	COG2362	D-Aminopeptidase
HUT19_RS09115	COG4106	trans-aconitate 2-methyltransferase activity
HUT19_RS09165	COG1309	transcriptional regulator
HUT19_RS09175	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUT19_RS09175	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUT19_RS09180	COG2301	Belongs to the HpcH HpaI aldolase family
HUT19_RS09190	COG1960	acyl-CoA dehydrogenase activity
HUT19_RS09195	COG0688	phosphatidylethanolamine metabolic process
HUT19_RS09215	COG1929	Belongs to the glycerate kinase type-1 family
HUT19_RS09225	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HUT19_RS09280	COG0181	hydroxymethylbilane synthase activity
HUT19_RS09295	COG0483	inositol monophosphate 1-phosphatase activity
HUT19_RS09300	COG1953	Uracil, thiamine, allantoin
HUT19_RS09305	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT19_RS09310	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HUT19_RS09315	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HUT19_RS09340	COG0405	Gamma-glutamyltransferase
HUT19_RS09355	COG0765	amino acid transport
HUT19_RS09360	COG0765	amino acid transport
HUT19_RS09365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUT19_RS09370	COG1126	abc transporter atp-binding protein
HUT19_RS09395	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUT19_RS09405	COG1940	carbohydrate kinase activity
HUT19_RS09425	COG2188	Transcriptional regulator
HUT19_RS09440	COG0800	Aldolase
HUT19_RS09490	COG4266	Belongs to the allantoicase family
HUT19_RS09495	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HUT19_RS09500	COG1414	Transcriptional regulator
HUT19_RS09555	COG3622	Belongs to the hyi family
HUT19_RS09560	COG2084	Dehydrogenase
HUT19_RS09580	COG0318	PFAM AMP-dependent synthetase and ligase
HUT19_RS09585	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUT19_RS09590	COG2197	response regulator
HUT19_RS09600	COG0598	Magnesium transport protein CorA
HUT19_RS09635	COG2252	PERMEase
HUT19_RS09640	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HUT19_RS09655	COG3835	regulator
HUT19_RS09665	COG1802	Transcriptional regulator
HUT19_RS09695	COG0028	Belongs to the TPP enzyme family
HUT19_RS09715	COG1162	GTPase activity
HUT19_RS09730	COG0456	acetyltransferase
HUT19_RS09735	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HUT19_RS09745	COG0175	sulfate reduction
HUT19_RS09750	COG0529	Catalyzes the synthesis of activated sulfate
HUT19_RS09810	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HUT19_RS09835	COG1175	transmembrane transport
HUT19_RS09880	COG0583	DNA-binding transcription factor activity
HUT19_RS09885	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HUT19_RS09900	COG2197	response regulator
HUT19_RS09915	COG1280	lysine exporter protein (LysE YggA)
HUT19_RS09920	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HUT19_RS09925	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HUT19_RS09990	COG5002	protein histidine kinase activity
HUT19_RS09995	COG0745	RESPONSE REGULATOR receiver
HUT19_RS10035	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HUT19_RS10040	COG3220	belongs to the UPF0276 family
HUT19_RS10070	COG1414	Transcriptional regulator
HUT19_RS10080	COG1414	Transcriptional regulator
HUT19_RS10085	COG2271	Major facilitator Superfamily
HUT19_RS10090	COG0446	pyridine nucleotide-disulphide oxidoreductase
HUT19_RS10100	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HUT19_RS10120	COG0183	Belongs to the thiolase family
HUT19_RS10125	COG1024	Enoyl-CoA hydratase
HUT19_RS10125	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUT19_RS10145	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HUT19_RS10160	COG0531	amino acid
HUT19_RS10165	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HUT19_RS10170	COG4214	carbohydrate transport
HUT19_RS10180	COG4213	ABC transporter substrate-binding protein
HUT19_RS10190	COG0395	ABC-type sugar transport system, permease component
HUT19_RS10195	COG1175	transmembrane transport
HUT19_RS10200	COG1653	transport
HUT19_RS10220	COG3537	Alpha-1,2-mannosidase
HUT19_RS10230	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HUT19_RS10255	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HUT19_RS10295	COG1024	Enoyl-CoA hydratase
HUT19_RS10305	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HUT19_RS10330	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HUT19_RS10340	COG2040	homocysteine
HUT19_RS10375	COG2423	ornithine cyclodeaminase activity
HUT19_RS10380	COG1802	Transcriptional regulator
HUT19_RS10395	COG0210	DNA helicase
HUT19_RS10410	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HUT19_RS10445	COG0515	serine threonine protein kinase
HUT19_RS10445	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HUT19_RS10450	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HUT19_RS10455	COG0531	amino acid
HUT19_RS10485	COG0569	domain protein
HUT19_RS10495	COG2826	transposase and inactivated derivatives, IS30 family
HUT19_RS10520	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
HUT19_RS10525	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HUT19_RS10530	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HUT19_RS10550	COG0756	dUTP diphosphatase activity
HUT19_RS10575	COG2205	protein histidine kinase activity
HUT19_RS10580	COG0745	RESPONSE REGULATOR receiver
HUT19_RS10590	COG0483	inositol monophosphate 1-phosphatase activity
HUT19_RS10640	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUT19_RS10640	COG1042	CoA-binding domain protein
HUT19_RS10640	COG0045	succinate-CoA ligase (ADP-forming) activity
HUT19_RS10645	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUT19_RS10650	COG1802	Transcriptional regulator
HUT19_RS10655	COG2826	transposase and inactivated derivatives, IS30 family
HUT19_RS10670	COG0612	Peptidase, M16
HUT19_RS10675	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HUT19_RS10690	COG3290	protein histidine kinase activity
HUT19_RS10695	COG4565	transcriptional regulatory protein
HUT19_RS10700	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUT19_RS10710	COG2197	response regulator
HUT19_RS10725	COG0187	DNA topoisomerase II activity
HUT19_RS10740	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HUT19_RS10745	COG1802	Transcriptional regulator
HUT19_RS10750	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HUT19_RS10765	COG0514	ATP-dependent DNA helicase (RecQ)
HUT19_RS10780	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HUT19_RS10790	COG0588	phosphoglycerate mutase activity
HUT19_RS10795	COG0488	(ABC) transporter
HUT19_RS10820	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HUT19_RS10855	COG2826	transposase and inactivated derivatives, IS30 family
HUT19_RS10860	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HUT19_RS10875	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HUT19_RS10880	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HUT19_RS10890	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HUT19_RS10915	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HUT19_RS10925	COG2205	protein histidine kinase activity
HUT19_RS10930	COG0745	RESPONSE REGULATOR receiver
HUT19_RS10935	COG1126	abc transporter atp-binding protein
HUT19_RS10940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUT19_RS10945	COG0765	amino acid transport
HUT19_RS10950	COG0765	amino acid transport
HUT19_RS10955	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT19_RS10965	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HUT19_RS10975	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HUT19_RS11005	COG1917	Cupin 2, conserved barrel domain protein
HUT19_RS11005	COG2207	Transcriptional regulator
HUT19_RS11010	COG1201	RNA secondary structure unwinding
HUT19_RS11015	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HUT19_RS11030	COG1396	sequence-specific DNA binding
HUT19_RS11035	COG1058	Belongs to the CinA family
HUT19_RS11035	COG1546	Belongs to the CinA family
HUT19_RS11045	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HUT19_RS11055	COG1674	ftsk spoiiie
HUT19_RS11065	COG2205	protein histidine kinase activity
HUT19_RS11065	COG4999	Histidine kinase
HUT19_RS11065	COG3850	Histidine kinase
HUT19_RS11065	COG3437	response regulator, receiver
HUT19_RS11070	COG2770	Histidine kinase
HUT19_RS11070	COG2208	phosphoserine phosphatase activity
HUT19_RS11075	COG3344	reverse transcriptase
HUT19_RS11085	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HUT19_RS11105	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HUT19_RS11110	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUT19_RS11115	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
HUT19_RS11135	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
HUT19_RS11140	COG0612	Peptidase, M16
HUT19_RS11145	COG1185	polyribonucleotide nucleotidyltransferase activity
HUT19_RS11150	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HUT19_RS11170	COG1674	ftsk spoiiie
HUT19_RS11200	COG1404	Belongs to the peptidase S8 family
HUT19_RS11205	COG3266	domain, Protein
HUT19_RS11230	COG0455	bacterial-type flagellum organization
HUT19_RS11240	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HUT19_RS11245	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HUT19_RS11255	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HUT19_RS11270	COG0779	Required for maturation of 30S ribosomal subunits
HUT19_RS11290	COG0442	prolyl-tRNA aminoacylation
HUT19_RS11295	COG0456	acetyltransferase
HUT19_RS11305	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HUT19_RS11310	COG0750	zinc metalloprotease
HUT19_RS11315	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HUT19_RS11330	COG1012	belongs to the aldehyde dehydrogenase family
HUT19_RS11335	COG2508	Transcriptional regulator
HUT19_RS11355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUT19_RS11360	COG1177	transmembrane transport
HUT19_RS11365	COG1176	ABC-type spermidine putrescine transport system, permease component I
HUT19_RS11370	COG3842	ATPase activity
HUT19_RS11380	COG1012	belongs to the aldehyde dehydrogenase family
HUT19_RS11400	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HUT19_RS11415	COG1012	belongs to the aldehyde dehydrogenase family
HUT19_RS11425	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HUT19_RS11440	COG0028	Belongs to the TPP enzyme family
HUT19_RS11445	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HUT19_RS11460	COG3842	ATPase activity
HUT19_RS11475	COG0820	rRNA (adenine-C2-)-methyltransferase activity
HUT19_RS11485	COG2188	Transcriptional regulator
HUT19_RS11520	COG1674	ftsk spoiiie
HUT19_RS11565	COG0575	Belongs to the CDS family
HUT19_RS11570	COG0233	cytoplasmic translational termination
HUT19_RS11575	COG0528	UMP kinase activity
HUT19_RS11580	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HUT19_RS11585	COG0052	Belongs to the universal ribosomal protein uS2 family
HUT19_RS11600	COG1191	sigma factor activity
HUT19_RS11615	COG0792	nuclease activity
HUT19_RS11630	COG0681	Belongs to the peptidase S26 family
HUT19_RS11635	COG0681	Belongs to the peptidase S26 family
HUT19_RS11650	COG0335	large ribosomal subunit rRNA binding
HUT19_RS11655	COG0336	Belongs to the RNA methyltransferase TrmD family
HUT19_RS11660	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HUT19_RS11665	COG1837	Belongs to the UPF0109 family
HUT19_RS11670	COG0228	four-way junction DNA binding
HUT19_RS11680	COG0442	prolyl-tRNA aminoacylation
HUT19_RS11695	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
HUT19_RS11730	COG4585	Histidine kinase
HUT19_RS11750	COG0477	Major facilitator Superfamily
HUT19_RS11755	COG1196	nuclear chromosome segregation
HUT19_RS11765	COG1254	Belongs to the acylphosphatase family
HUT19_RS11775	COG0655	NAD(P)H dehydrogenase (quinone) activity
HUT19_RS11780	COG1733	regulation of RNA biosynthetic process
HUT19_RS11785	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HUT19_RS11790	COG0571	ribonuclease III activity
HUT19_RS11795	COG0333	Belongs to the bacterial ribosomal protein bL32 family
HUT19_RS11810	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HUT19_RS11815	COG0742	ribosomal rna small subunit methyltransferase
HUT19_RS11820	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HUT19_RS11825	COG1461	Dihydroxyacetone kinase
HUT19_RS11830	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HUT19_RS11835	COG0351	phosphomethylpyrimidine kinase
HUT19_RS11855	COG1181	Belongs to the D-alanine--D-alanine ligase family
HUT19_RS11860	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
HUT19_RS11870	COG1920	GTP binding
HUT19_RS11880	COG0776	regulation of translation
HUT19_RS11890	COG0066	3-isopropylmalate dehydratase activity
HUT19_RS11895	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HUT19_RS11900	COG1414	Transcriptional regulator
HUT19_RS11940	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HUT19_RS11945	COG0179	Fumarylacetoacetate (FAA) hydrolase
HUT19_RS11955	COG5002	protein histidine kinase activity
HUT19_RS11960	COG2018	Roadblock/LC7 domain
HUT19_RS11980	COG2018	Roadblock/LC7 domain
HUT19_RS12000	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUT19_RS12005	COG2353	YceI-like domain
HUT19_RS12010	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HUT19_RS12015	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HUT19_RS12020	COG0473	3-isopropylmalate dehydrogenase activity
HUT19_RS12030	COG1012	belongs to the aldehyde dehydrogenase family
HUT19_RS12035	COG0506	proline dehydrogenase activity
HUT19_RS12055	COG0477	Major facilitator Superfamily
HUT19_RS12080	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HUT19_RS12085	COG0440	acetolactate synthase activity
HUT19_RS12105	COG0667	Aldo Keto reductase
HUT19_RS12110	COG2133	pyrroloquinoline quinone binding
HUT19_RS12120	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
HUT19_RS12120	COG1672	PFAM Archaeal ATPase
HUT19_RS12130	COG2409	Drug exporters of the RND superfamily
HUT19_RS12145	COG1940	carbohydrate kinase activity
HUT19_RS12155	COG0395	ABC-type sugar transport system, permease component
HUT19_RS12160	COG1175	transmembrane transport
HUT19_RS12165	COG1653	transport
HUT19_RS12170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUT19_RS12175	COG2222	sugar isomerase
HUT19_RS12190	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HUT19_RS12200	COG0154	amidase activity
HUT19_RS12205	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HUT19_RS12215	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HUT19_RS12230	COG1611	Belongs to the LOG family
HUT19_RS12240	COG0482	sulfurtransferase activity
HUT19_RS12280	COG2860	membrane
HUT19_RS12285	COG4608	Belongs to the ABC transporter superfamily
HUT19_RS12290	COG0444	Belongs to the ABC transporter superfamily
HUT19_RS12300	COG4166	transmembrane transport
HUT19_RS12325	COG0404	The glycine cleavage system catalyzes the degradation of glycine
HUT19_RS12330	COG0509	glycine decarboxylation via glycine cleavage system
HUT19_RS12335	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HUT19_RS12340	COG1760	l-serine dehydratase
HUT19_RS12355	COG0318	PFAM AMP-dependent synthetase and ligase
HUT19_RS12400	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HUT19_RS12420	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HUT19_RS12485	COG1132	(ABC) transporter
HUT19_RS12490	COG1132	(ABC) transporter
HUT19_RS12515	COG0058	SHG alpha-glucan phosphorylase activity
HUT19_RS12530	COG0366	Alpha amylase catalytic
HUT19_RS12540	COG3281	Trehalose synthase
HUT19_RS12545	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HUT19_RS12560	COG1301	dicarboxylic acid transport
HUT19_RS12565	COG3290	protein histidine kinase activity
HUT19_RS12570	COG4565	transcriptional regulatory protein
HUT19_RS12580	COG1175	transmembrane transport
HUT19_RS12585	COG0124	histidyl-tRNA synthetase
HUT19_RS12640	COG2318	DinB family
HUT19_RS12645	COG3833	ABC-type maltose transport systems, permease component
HUT19_RS12665	COG0205	6-phosphofructokinase activity
HUT19_RS12670	COG0857	belongs to the CobB CobQ family
HUT19_RS12670	COG0280	phosphate acetyltransferase
HUT19_RS12675	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HUT19_RS12715	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUT19_RS12715	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUT19_RS12765	COG3850	Histidine kinase
HUT19_RS12765	COG5002	protein histidine kinase activity
HUT19_RS12770	COG0745	RESPONSE REGULATOR receiver
HUT19_RS12785	COG0183	Belongs to the thiolase family
HUT19_RS12845	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
HUT19_RS12860	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUT19_RS12890	COG4585	Histidine kinase
HUT19_RS12895	COG2197	response regulator
HUT19_RS12905	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HUT19_RS12910	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HUT19_RS12915	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HUT19_RS12920	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HUT19_RS12925	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HUT19_RS12930	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HUT19_RS12935	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HUT19_RS12950	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HUT19_RS12955	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HUT19_RS12960	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HUT19_RS12970	COG2890	protein-(glutamine-N5) methyltransferase activity
HUT19_RS12975	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HUT19_RS12980	COG0254	rRNA binding
HUT19_RS12985	COG1316	TRANSCRIPTIONal
HUT19_RS12995	COG0083	homoserine kinase activity
HUT19_RS13000	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HUT19_RS13005	COG0460	homoserine dehydrogenase
HUT19_RS13010	COG0019	diaminopimelate decarboxylase activity
HUT19_RS13015	COG0018	arginyl-trna synthetase
HUT19_RS13040	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HUT19_RS13050	COG0515	serine threonine protein kinase
HUT19_RS13050	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HUT19_RS13095	COG0477	Major facilitator Superfamily
HUT19_RS13115	COG0583	DNA-binding transcription factor activity
HUT19_RS13150	COG3103	Sh3 type 3 domain protein
HUT19_RS13150	COG0791	NLP P60 protein
HUT19_RS13150	COG1388	LysM domain
HUT19_RS13195	COG1309	transcriptional regulator
HUT19_RS13200	COG2249	NAD(P)H dehydrogenase (quinone) activity
HUT19_RS13205	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HUT19_RS13220	COG0745	RESPONSE REGULATOR receiver
HUT19_RS13225	COG2205	protein histidine kinase activity
HUT19_RS13230	COG0567	Dehydrogenase, E1 component
HUT19_RS13230	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUT19_RS13240	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
HUT19_RS13260	COG0778	Nitroreductase
HUT19_RS13275	COG3321	synthase
HUT19_RS13275	COG0318	PFAM AMP-dependent synthetase and ligase
HUT19_RS13275	COG0300	oxidoreductase activity
HUT19_RS13275	COG1028	Short-chain dehydrogenase reductase Sdr
HUT19_RS13275	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT19_RS13310	COG0604	alcohol dehydrogenase
HUT19_RS13315	COG0281	malic enzyme
HUT19_RS13325	COG0765	amino acid transport
HUT19_RS13330	COG1126	abc transporter atp-binding protein
HUT19_RS13360	COG0583	DNA-binding transcription factor activity
HUT19_RS13400	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUT19_RS13420	COG2066	Belongs to the glutaminase family
HUT19_RS13460	COG1597	lipid kinase activity
HUT19_RS13475	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HUT19_RS13480	COG1472	Belongs to the glycosyl hydrolase 3 family
HUT19_RS13485	COG0395	ABC-type sugar transport system, permease component
HUT19_RS13490	COG1175	transmembrane transport
HUT19_RS13495	COG2182	Extracellular solute-binding protein
HUT19_RS13500	COG2188	Transcriptional regulator
HUT19_RS13525	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HUT19_RS13530	COG1349	DNA-binding transcription factor activity
HUT19_RS13535	COG0588	phosphoglycerate mutase activity
HUT19_RS13555	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HUT19_RS13560	COG0242	peptide deformylase activity
HUT19_RS13575	COG2199	diguanylate cyclase activity
HUT19_RS13575	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HUT19_RS13580	COG5662	AntiSigma factor
HUT19_RS13585	COG1595	DNA-templated transcription, initiation
HUT19_RS13595	COG2135	peptidase activity
HUT19_RS13605	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HUT19_RS13625	COG0483	inositol monophosphate 1-phosphatase activity
HUT19_RS13630	COG0517	IMP dehydrogenase activity
HUT19_RS13630	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HUT19_RS13635	COG0753	catalase activity
HUT19_RS13660	COG1615	UPF0182 protein
HUT19_RS13670	COG3480	Lon protease (S16) C-terminal proteolytic domain
HUT19_RS13725	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HUT19_RS13820	COG0438	transferase activity, transferring glycosyl groups
HUT19_RS13860	COG0513	Belongs to the DEAD box helicase family
HUT19_RS13865	COG0596	Alpha beta hydrolase
HUT19_RS13870	COG1432	Conserved Protein
HUT19_RS13880	COG2095	MarC family integral membrane protein
HUT19_RS13885	COG0613	PHP domain protein
HUT19_RS13900	COG0598	Magnesium transport protein CorA
HUT19_RS13940	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HUT19_RS13945	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUT19_RS13955	COG1595	DNA-templated transcription, initiation
HUT19_RS13970	COG1024	Enoyl-CoA hydratase
HUT19_RS13975	COG0519	Catalyzes the synthesis of GMP from XMP
HUT19_RS13985	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HUT19_RS13990	COG1611	Belongs to the LOG family
HUT19_RS13995	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUT19_RS14040	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HUT19_RS14060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUT19_RS14065	COG0747	negative chemotaxis
HUT19_RS14075	COG0444	Belongs to the ABC transporter superfamily
HUT19_RS14080	COG4608	Belongs to the ABC transporter superfamily
HUT19_RS14110	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HUT19_RS14130	COG0494	nUDIX hydrolase
HUT19_RS14140	COG4608	Belongs to the ABC transporter superfamily
HUT19_RS14150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUT19_RS14155	COG0601	transmembrane transport
HUT19_RS14160	COG4166	transmembrane transport
HUT19_RS14165	COG4608	Belongs to the ABC transporter superfamily
HUT19_RS14175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUT19_RS14180	COG0601	transmembrane transport
HUT19_RS14195	COG4166	transmembrane transport
HUT19_RS14240	COG0531	amino acid
HUT19_RS14270	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUT19_RS14280	COG0494	nUDIX hydrolase
HUT19_RS14305	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HUT19_RS14315	COG0012	GTP binding
HUT19_RS14330	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HUT19_RS14335	COG1570	exodeoxyribonuclease VII activity
HUT19_RS14340	COG1722	exodeoxyribonuclease VII activity
HUT19_RS14345	COG0778	Nitroreductase
HUT19_RS14370	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HUT19_RS14370	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HUT19_RS14375	COG3979	chitinase
HUT19_RS14385	COG0726	polysaccharide deacetylase
HUT19_RS14390	COG0114	fumarate hydratase activity
HUT19_RS14400	COG2226	methyltransferase
HUT19_RS14410	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HUT19_RS14430	COG1136	(ABC) transporter
HUT19_RS14445	COG0450	alkyl hydroperoxide reductase
HUT19_RS14450	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUT19_RS14465	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
HUT19_RS14470	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HUT19_RS14475	COG0667	Aldo Keto reductase
HUT19_RS14490	COG1278	Cold shock
HUT19_RS14500	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HUT19_RS14505	COG2885	chlorophyll binding
HUT19_RS14545	COG2894	cell division
HUT19_RS14580	COG2610	gluconate transmembrane transporter activity
HUT19_RS14590	COG1414	Transcriptional regulator
HUT19_RS14605	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
HUT19_RS14620	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
HUT19_RS14625	COG1272	protein, Hemolysin III
HUT19_RS14635	COG1331	Highly conserved protein containing a thioredoxin domain
HUT19_RS14650	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HUT19_RS14660	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HUT19_RS14675	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HUT19_RS14685	COG1595	DNA-templated transcription, initiation
HUT19_RS14705	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HUT19_RS14735	COG3629	intracellular signal transduction
HUT19_RS14735	COG3903	Transcriptional regulator
HUT19_RS14805	COG2018	Roadblock/LC7 domain
HUT19_RS14830	COG0740	serine-type endopeptidase activity
HUT19_RS14835	COG0740	serine-type endopeptidase activity
HUT19_RS14920	COG0667	Aldo Keto reductase
HUT19_RS14925	COG0577	efflux transmembrane transporter activity
HUT19_RS14925	COG1136	(ABC) transporter
HUT19_RS14930	COG1136	(ABC) transporter
HUT19_RS14935	COG0477	Major facilitator Superfamily
HUT19_RS14965	COG4585	Histidine kinase
HUT19_RS14975	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HUT19_RS14980	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HUT19_RS14985	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HUT19_RS14990	COG0193	aminoacyl-tRNA hydrolase activity
HUT19_RS15000	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HUT19_RS15010	COG1309	transcriptional regulator
HUT19_RS15020	COG4106	trans-aconitate 2-methyltransferase activity
HUT19_RS15025	COG1846	Transcriptional regulator
HUT19_RS15030	COG2197	response regulator
HUT19_RS15035	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HUT19_RS15070	COG0488	(ABC) transporter
HUT19_RS15075	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HUT19_RS15080	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HUT19_RS15085	COG3584	3D domain protein
HUT19_RS15085	COG3583	domain protein
HUT19_RS15090	COG0084	hydrolase, TatD family'
HUT19_RS15120	COG3903	Transcriptional regulator
HUT19_RS15120	COG3629	intracellular signal transduction
HUT19_RS15150	COG1122	ATPase activity
HUT19_RS15160	COG0310	cobalt ion transport
HUT19_RS15165	COG2409	Drug exporters of the RND superfamily
HUT19_RS15175	COG4946	Tricorn protease homolog
HUT19_RS15175	COG0793	Belongs to the peptidase S41A family
HUT19_RS15190	COG2267	carboxylic ester hydrolase activity
HUT19_RS15195	COG2072	flavoprotein involved in K transport
HUT19_RS15250	COG0708	Exodeoxyribonuclease III
HUT19_RS15305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUT19_RS15310	COG0521	Mo-molybdopterin cofactor biosynthetic process
HUT19_RS15310	COG0315	cyclic pyranopterin monophosphate synthase activity
HUT19_RS15315	COG0315	cyclic pyranopterin monophosphate synthase activity
HUT19_RS15325	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HUT19_RS15330	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HUT19_RS15340	COG3263	regulation of cellular component size
HUT19_RS15350	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HUT19_RS15360	COG1970	mechanosensitive ion channel activity
HUT19_RS15370	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUT19_RS15380	COG3634	alkyl hydroperoxide reductase activity
HUT19_RS15385	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HUT19_RS15385	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HUT19_RS15385	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HUT19_RS15390	COG1105	Belongs to the carbohydrate kinase PfkB family
HUT19_RS15395	COG1349	DNA-binding transcription factor activity
HUT19_RS15400	COG1028	Short-chain dehydrogenase reductase Sdr
HUT19_RS15420	COG3384	dioxygenase
HUT19_RS15425	COG1846	Transcriptional regulator
HUT19_RS15430	COG2826	transposase and inactivated derivatives, IS30 family
HUT19_RS15480	COG3486	L-lysine 6-monooxygenase (NADPH) activity
HUT19_RS15540	COG2226	methyltransferase
HUT19_RS15570	COG0640	Transcriptional regulator
HUT19_RS15590	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HUT19_RS15605	COG0798	PFAM Bile acid sodium symporter
HUT19_RS15625	COG0640	Transcriptional regulator
HUT19_RS15770	COG4974	Belongs to the 'phage' integrase family
HUT19_RS15805	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HUT19_RS15860	COG3335	DDE superfamily endonuclease
HUT19_RS15870	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HUT19_RS15920	COG3547	Transposase (IS116 IS110 IS902 family)
HUT19_RS15945	COG1028	Short-chain dehydrogenase reductase Sdr
HUT19_RS15955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT19_RS15970	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUT19_RS15985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT19_RS16015	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT19_RS16025	COG1028	Short-chain dehydrogenase reductase Sdr
HUT19_RS16030	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUT19_RS16055	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUT19_RS16080	COG0028	Belongs to the TPP enzyme family
HUT19_RS16085	COG1012	belongs to the aldehyde dehydrogenase family
HUT19_RS16090	COG1028	Short-chain dehydrogenase reductase Sdr
HUT19_RS16115	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT19_RS16135	COG0655	NAD(P)H dehydrogenase (quinone) activity
HUT19_RS16140	COG1012	belongs to the aldehyde dehydrogenase family
HUT19_RS16170	COG1414	Transcriptional regulator
HUT19_RS16180	COG1228	amidohydrolase
HUT19_RS16230	COG3246	L-lysine catabolic process to acetate
HUT19_RS16235	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUT19_RS16240	COG0824	Thioesterase
HUT19_RS16240	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUT19_RS16255	COG2515	1-aminocyclopropane-1-carboxylate deaminase
HUT19_RS16260	COG1793	dna ligase
HUT19_RS16265	COG1793	dna ligase
HUT19_RS16265	COG3285	dna ligase
HUT19_RS16270	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HUT19_RS16275	COG0702	epimerase
HUT19_RS16305	COG0515	serine threonine protein kinase
HUT19_RS16320	COG1653	transport
HUT19_RS16335	COG1686	Belongs to the peptidase S11 family
HUT19_RS16360	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT19_RS16365	COG1028	Short-chain dehydrogenase reductase Sdr
HUT19_RS16390	COG2226	methyltransferase
HUT19_RS16395	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
HUT19_RS16430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT19_RS16480	COG1024	Enoyl-CoA hydratase
HUT19_RS16490	COG0515	serine threonine protein kinase
HUT19_RS16490	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HUT19_RS16500	COG1309	transcriptional regulator
HUT19_RS16510	COG1960	acyl-CoA dehydrogenase activity
HUT19_RS16520	COG0259	pyridoxamine-phosphate oxidase activity
HUT19_RS16540	COG2072	flavoprotein involved in K transport
HUT19_RS16550	COG1024	Enoyl-CoA hydratase
HUT19_RS16555	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HUT19_RS16575	COG1012	belongs to the aldehyde dehydrogenase family
HUT19_RS16580	COG1960	acyl-CoA dehydrogenase activity
HUT19_RS16585	COG1028	Short-chain dehydrogenase reductase Sdr
HUT19_RS16600	COG1960	acyl-CoA dehydrogenase activity
HUT19_RS16605	COG1960	acyl-CoA dehydrogenase activity
HUT19_RS16610	COG0318	PFAM AMP-dependent synthetase and ligase
HUT19_RS16630	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HUT19_RS16650	COG1077	Cell shape determining protein MreB Mrl
HUT19_RS16665	COG2826	transposase and inactivated derivatives, IS30 family
HUT19_RS16670	COG0516	GMP reductase activity
HUT19_RS16680	COG1595	DNA-templated transcription, initiation
HUT19_RS16685	COG2197	response regulator
HUT19_RS16695	COG0583	DNA-binding transcription factor activity
HUT19_RS16705	COG4221	oxidoreductase activity
HUT19_RS16715	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HUT19_RS16770	COG2188	Transcriptional regulator
HUT19_RS16775	COG0726	polysaccharide deacetylase
HUT19_RS16810	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HUT19_RS16850	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HUT19_RS16875	COG0802	atpase or kinase
HUT19_RS16885	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HUT19_RS16910	COG0736	holo-[acyl-carrier-protein] synthase activity
HUT19_RS16915	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HUT19_RS16920	COG1072	(Pantothenic acid kinase))
HUT19_RS16930	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HUT19_RS16935	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HUT19_RS16940	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HUT19_RS16945	COG0488	(ABC) transporter
HUT19_RS16960	COG0438	transferase activity, transferring glycosyl groups
HUT19_RS16970	COG2770	Histidine kinase
HUT19_RS16970	COG2208	phosphoserine phosphatase activity
HUT19_RS16980	COG2172	sigma factor antagonist activity
HUT19_RS16985	COG1366	Belongs to the anti-sigma-factor antagonist family
HUT19_RS16995	COG1366	Belongs to the anti-sigma-factor antagonist family
HUT19_RS17000	COG0101	tRNA pseudouridine synthase activity
HUT19_RS17005	COG0203	ribosomal protein L17
HUT19_RS17010	COG0202	RNA polymerase activity
HUT19_RS17015	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HUT19_RS17020	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HUT19_RS17025	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HUT19_RS17030	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HUT19_RS17035	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HUT19_RS17045	COG0563	adenylate kinase activity
HUT19_RS17055	COG0200	Binds to the 23S rRNA
HUT19_RS17065	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HUT19_RS17070	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HUT19_RS17075	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HUT19_RS17080	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HUT19_RS17085	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HUT19_RS17090	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HUT19_RS17095	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HUT19_RS17100	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HUT19_RS17105	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HUT19_RS17110	COG0255	Belongs to the universal ribosomal protein uL29 family
HUT19_RS17115	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HUT19_RS17120	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HUT19_RS17125	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HUT19_RS17130	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HUT19_RS17135	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HUT19_RS17140	COG0089	rRNA binding
HUT19_RS17145	COG0088	Forms part of the polypeptide exit tunnel
HUT19_RS17150	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HUT19_RS17155	COG0051	transcription antitermination factor activity, RNA binding
HUT19_RS17190	COG3344	reverse transcriptase
HUT19_RS17195	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HUT19_RS17200	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HUT19_RS17205	COG0049	tRNA binding
HUT19_RS17210	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HUT19_RS17215	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HUT19_RS17220	COG0085	RNA polymerase activity
HUT19_RS17225	COG0222	ribosome binding
HUT19_RS17230	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HUT19_RS17240	COG0081	regulation of translation
HUT19_RS17245	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HUT19_RS17250	COG0250	Participates in transcription elongation, termination and antitermination
HUT19_RS17265	COG0436	Aminotransferase
HUT19_RS17270	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HUT19_RS17275	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HUT19_RS17285	COG2030	dehydratase
HUT19_RS17290	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HUT19_RS17310	COG0702	epimerase
HUT19_RS17330	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HUT19_RS17405	COG2188	Transcriptional regulator
HUT19_RS17420	COG1666	GTP binding
HUT19_RS17425	COG3304	Inner membrane component domain
HUT19_RS17430	COG0501	Belongs to the peptidase M48B family
HUT19_RS17435	COG1007	ATP synthesis coupled electron transport
HUT19_RS17445	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HUT19_RS17450	COG0713	ATP synthesis coupled electron transport
HUT19_RS17455	COG0839	Belongs to the complex I subunit 6 family
HUT19_RS17460	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT19_RS17465	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HUT19_RS17470	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT19_RS17475	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT19_RS17480	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT19_RS17485	COG4585	Histidine kinase
HUT19_RS17495	COG0674	pyruvate-flavodoxin oxidoreductase activity
HUT19_RS17495	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HUT19_RS17500	COG1013	pyruvate-flavodoxin oxidoreductase activity
HUT19_RS17505	COG0531	amino acid
HUT19_RS17510	COG1733	regulation of RNA biosynthetic process
HUT19_RS17515	COG0702	epimerase
HUT19_RS17585	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
HUT19_RS17590	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HUT19_RS17595	COG1007	ATP synthesis coupled electron transport
HUT19_RS17605	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HUT19_RS17610	COG0713	ATP synthesis coupled electron transport
HUT19_RS17615	COG0839	Belongs to the complex I subunit 6 family
HUT19_RS17620	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT19_RS17625	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HUT19_RS17630	COG1034	ATP synthesis coupled electron transport
HUT19_RS17635	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HUT19_RS17645	COG0649	NAD binding
HUT19_RS17650	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT19_RS17655	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT19_RS17690	COG2226	methyltransferase
HUT19_RS17700	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
HUT19_RS17710	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
HUT19_RS17735	COG1309	transcriptional regulator
HUT19_RS17740	COG1301	dicarboxylic acid transport
HUT19_RS17755	COG1573	uracil-dna glycosylase
HUT19_RS17760	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
HUT19_RS17775	COG0163	prenyltransferase activity
HUT19_RS17780	COG0109	protoheme IX farnesyltransferase activity
HUT19_RS17785	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HUT19_RS17795	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HUT19_RS17800	COG1333	cytochrome c biogenesis protein
HUT19_RS17805	COG0785	Cytochrome C biogenesis protein
HUT19_RS17810	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HUT19_RS17820	COG0406	alpha-ribazole phosphatase activity
HUT19_RS17825	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HUT19_RS17855	COG1690	Belongs to the RtcB family
HUT19_RS17875	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
HUT19_RS17880	COG0018	arginyl-trna synthetase
HUT19_RS17905	COG1072	(Pantothenic acid kinase))
HUT19_RS17910	COG0113	porphobilinogen synthase activity
HUT19_RS17915	COG1648	precorrin-2 dehydrogenase activity
HUT19_RS17915	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HUT19_RS17920	COG0181	hydroxymethylbilane synthase activity
HUT19_RS17925	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HUT19_RS17930	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HUT19_RS17980	COG0123	including yeast histone deacetylase and acetoin utilization protein
HUT19_RS17990	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUT19_RS18010	COG0180	Tryptophanyl-tRNA synthetase
HUT19_RS18015	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HUT19_RS18020	COG0659	secondary active sulfate transmembrane transporter activity
HUT19_RS18025	COG0515	serine threonine protein kinase
HUT19_RS18025	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HUT19_RS18035	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HUT19_RS18035	COG0515	serine threonine protein kinase
HUT19_RS18050	COG0129	dihydroxy-acid dehydratase activity
HUT19_RS18060	COG1082	Xylose isomerase domain protein TIM barrel
HUT19_RS18065	COG0248	Ppx GppA phosphatase
HUT19_RS18085	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HUT19_RS18095	COG1194	a g-specific adenine glycosylase
HUT19_RS18100	COG1595	DNA-templated transcription, initiation
HUT19_RS18110	COG0745	RESPONSE REGULATOR receiver
HUT19_RS18115	COG2205	protein histidine kinase activity
HUT19_RS18120	COG0346	lactoylglutathione lyase activity
HUT19_RS18140	COG0739	heme binding
HUT19_RS18145	COG0724	RNA recognition motif
HUT19_RS18155	COG2205	protein histidine kinase activity
HUT19_RS18160	COG0745	RESPONSE REGULATOR receiver
HUT19_RS18165	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUT19_RS18170	COG1609	Transcriptional regulator
HUT19_RS18175	COG0745	RESPONSE REGULATOR receiver
HUT19_RS18210	COG2897	thiosulfate sulfurtransferase activity
HUT19_RS18230	COG3485	protocatechuate 3,4-dioxygenase
HUT19_RS18235	COG0735	belongs to the Fur family
HUT19_RS18250	COG0577	efflux transmembrane transporter activity
HUT19_RS18250	COG1136	(ABC) transporter
HUT19_RS18255	COG1695	Transcriptional regulator
HUT19_RS18260	COG1653	transport
HUT19_RS18265	COG0366	Alpha amylase catalytic
HUT19_RS18275	COG1175	transmembrane transport
HUT19_RS18280	COG0395	ABC-type sugar transport system, permease component
HUT19_RS18285	COG1490	D-aminoacyl-tRNA deacylase activity
HUT19_RS18295	COG4552	Acetyltransferase involved in intracellular survival and related
HUT19_RS18325	COG2249	NAD(P)H dehydrogenase (quinone) activity
HUT19_RS18340	COG0667	Aldo Keto reductase
HUT19_RS18365	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HUT19_RS18390	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HUT19_RS18395	COG0306	phosphate transporter
HUT19_RS18405	COG1937	Protein conserved in bacteria
HUT19_RS18425	COG0277	FAD linked oxidase domain protein
HUT19_RS18430	COG0671	phosphoesterase, PA-phosphatase related
HUT19_RS18435	COG1196	nuclear chromosome segregation
HUT19_RS18435	COG0741	lytic transglycosylase activity
HUT19_RS18435	COG0739	heme binding
HUT19_RS18505	COG1252	NADH dehydrogenase
HUT19_RS18530	COG0579	oxidoreductase
HUT19_RS18535	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HUT19_RS18580	COG0667	Aldo Keto reductase
HUT19_RS18630	COG0513	Belongs to the DEAD box helicase family
HUT19_RS18690	COG1643	Atp-dependent helicase
HUT19_RS18720	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HUT19_RS18730	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
HUT19_RS18750	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HUT19_RS18755	COG0047	phosphoribosylformylglycinamidine synthase activity
HUT19_RS18760	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HUT19_RS18795	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
HUT19_RS18810	COG0151	Belongs to the GarS family
HUT19_RS18865	COG0463	Glycosyl transferase, family 2
HUT19_RS18870	COG1802	Transcriptional regulator
HUT19_RS18875	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HUT19_RS18880	COG0693	protein deglycase activity
HUT19_RS18905	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HUT19_RS18920	COG1131	(ABC) transporter
HUT19_RS18925	COG3559	Exporter of polyketide antibiotics
HUT19_RS18930	COG2124	cytochrome p450
HUT19_RS18935	COG2197	response regulator
HUT19_RS18940	COG4585	Histidine kinase
HUT19_RS18950	COG3844	kynureninase activity
HUT19_RS18955	COG3483	tryptophan 2,3-dioxygenase activity
HUT19_RS18965	COG0477	Major facilitator Superfamily
HUT19_RS18970	COG0191	fructose-bisphosphate aldolase activity
HUT19_RS18975	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HUT19_RS18990	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HUT19_RS19015	COG0542	response to heat
HUT19_RS19040	COG0789	Transcriptional regulator
HUT19_RS19045	COG0484	heat shock protein binding
HUT19_RS19050	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HUT19_RS19055	COG0443	Heat shock 70 kDa protein
HUT19_RS19060	COG2181	nitrate reductase activity
HUT19_RS19060	COG0247	lactate metabolic process
HUT19_RS19095	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
HUT19_RS19100	COG0717	Belongs to the dCTP deaminase family
HUT19_RS19165	COG2188	Transcriptional regulator
HUT19_RS19200	COG4249	Peptidase C14 caspase catalytic subunit p20
HUT19_RS19200	COG2319	Wd-40 repeat
HUT19_RS19210	COG2801	Transposase and inactivated derivatives
HUT19_RS19230	COG3335	DDE superfamily endonuclease
HUT19_RS19300	COG1132	(ABC) transporter
HUT19_RS19310	COG2402	Toxic component of a toxin-antitoxin (TA) module. An RNase
HUT19_RS19380	COG2197	response regulator
HUT19_RS19385	COG4585	Histidine kinase
HUT19_RS19395	COG0583	DNA-binding transcription factor activity
HUT19_RS19400	COG0384	phenazine biosynthesis protein PhzF
HUT19_RS19420	COG0725	ABC transporter, periplasmic molybdate-binding protein
HUT19_RS19480	COG2205	protein histidine kinase activity
HUT19_RS19495	COG0640	Transcriptional regulator
HUT19_RS19515	COG2124	cytochrome p450
HUT19_RS19530	COG2018	Roadblock/LC7 domain
HUT19_RS19540	COG3290	protein histidine kinase activity
HUT19_RS19555	COG1793	dna ligase
HUT19_RS19560	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUT19_RS19560	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUT19_RS19605	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HUT19_RS19615	COG1741	Belongs to the pirin family
HUT19_RS19625	COG1960	acyl-CoA dehydrogenase activity
HUT19_RS19640	COG1362	aminopeptidase activity
HUT19_RS19645	COG3903	Transcriptional regulator
HUT19_RS19645	COG3629	intracellular signal transduction
HUT19_RS19700	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUT19_RS19705	COG0022	dehydrogenase e1 component
HUT19_RS19725	COG0515	serine threonine protein kinase
HUT19_RS19730	COG0515	serine threonine protein kinase
HUT19_RS19745	COG0604	alcohol dehydrogenase
HUT19_RS19745	COG1028	Short-chain dehydrogenase reductase Sdr
HUT19_RS19745	COG3321	synthase
HUT19_RS19750	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HUT19_RS19780	COG1522	sequence-specific DNA binding
HUT19_RS19785	COG1309	transcriptional regulator
HUT19_RS19790	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUT19_RS19825	COG3396	Phenylacetate-CoA oxygenase
HUT19_RS19830	COG3460	Phenylacetate-CoA oxygenase
HUT19_RS19835	COG3396	Phenylacetate-CoA oxygenase
HUT19_RS19840	COG2151	metal-sulfur cluster biosynthetic enzyme
HUT19_RS19845	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUT19_RS19870	COG1733	regulation of RNA biosynthetic process
HUT19_RS19875	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HUT19_RS19880	COG3344	reverse transcriptase
HUT19_RS19895	COG3335	DDE superfamily endonuclease
HUT19_RS19945	COG0640	Transcriptional regulator
HUT19_RS19960	COG1253	flavin adenine dinucleotide binding
HUT19_RS19965	COG3594	Acyltransferase
HUT19_RS20005	COG1716	ATPase activity
HUT19_RS20010	COG1716	ATPase activity
HUT19_RS20025	COG0768	penicillin binding
HUT19_RS20030	COG0515	serine threonine protein kinase
HUT19_RS20035	COG3764	Sortase (surface protein transpeptidase)
HUT19_RS20040	COG3764	Sortase (surface protein transpeptidase)
HUT19_RS20055	COG3764	Sortase (surface protein transpeptidase)
HUT19_RS20100	COG0515	serine threonine protein kinase
HUT19_RS20125	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HUT19_RS20130	COG0187	DNA topoisomerase II activity
HUT19_RS20135	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
HUT19_RS20140	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HUT19_RS20145	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
HUT19_RS20150	COG0592	DNA-directed DNA polymerase activity
HUT19_RS20160	COG0230	Belongs to the bacterial ribosomal protein bL34 family
HUT19_RS20165	COG0594	ribonuclease P activity
HUT19_RS20170	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
HUT19_RS20175	COG0706	membrane insertase activity
HUT19_RS20185	COG0357	Ribosomal RNA small subunit methyltransferase G
HUT19_RS20190	COG1192	Involved in chromosome partitioning
HUT19_RS20205	COG3118	belongs to the thioredoxin family
HUT19_RS20220	COG1595	DNA-templated transcription, initiation
HUT19_RS20225	COG0515	serine threonine protein kinase
HUT19_RS20225	COG2815	serine threonine protein kinase
HUT19_RS20240	COG0617	tRNA 3'-terminal CCA addition
HUT19_RS20250	COG1260	myo-inositol-1-phosphate synthase
HUT19_RS20260	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HUT19_RS20285	COG0360	Binds together with S18 to 16S ribosomal RNA
HUT19_RS20290	COG0629	single-stranded DNA binding
HUT19_RS20295	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HUT19_RS20300	COG0359	binds to the 23S rRNA
HUT19_RS20310	COG0305	Participates in initiation and elongation during chromosome replication
HUT19_RS20330	COG1028	Short-chain dehydrogenase reductase Sdr
HUT19_RS20405	COG0626	cystathionine gamma-synthase activity
HUT19_RS20410	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HUT19_RS20415	COG1950	PFAM Membrane protein of
HUT19_RS20420	COG0662	Cupin 2, conserved barrel domain protein
HUT19_RS20440	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HUT19_RS20450	COG1733	regulation of RNA biosynthetic process
HUT19_RS20465	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HUT19_RS20470	COG1609	Transcriptional regulator
HUT19_RS20475	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HUT19_RS20480	COG1271	oxidase subunit
HUT19_RS20485	COG1294	oxidase, subunit
HUT19_RS20490	COG4988	ABC transporter
HUT19_RS20505	COG0561	phosphatase activity
HUT19_RS20515	COG0501	Belongs to the peptidase M48B family
HUT19_RS20525	COG1028	Short-chain dehydrogenase reductase Sdr
HUT19_RS20530	COG1131	(ABC) transporter
HUT19_RS20550	COG2378	regulation of single-species biofilm formation
HUT19_RS20565	COG0561	phosphatase activity
HUT19_RS20570	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HUT19_RS20580	COG2837	iron assimilation
HUT19_RS20595	COG1999	signal sequence binding
HUT19_RS20615	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT19_RS20620	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUT19_RS20625	COG0006	proline dipeptidase activity
HUT19_RS20640	COG0653	protein targeting
HUT19_RS20655	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUT19_RS20780	COG0758	DNA mediated transformation
HUT19_RS20785	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HUT19_RS20820	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HUT19_RS20825	COG0798	PFAM Bile acid sodium symporter
HUT19_RS20830	COG0640	Transcriptional regulator
HUT19_RS20900	COG1595	DNA-templated transcription, initiation
HUT19_RS20905	COG0318	PFAM AMP-dependent synthetase and ligase
HUT19_RS20930	COG0582	viral genome integration into host DNA
HUT19_RS20965	COG2188	Transcriptional regulator
HUT19_RS20970	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HUT19_RS20995	COG3335	DDE superfamily endonuclease
HUT19_RS21015	COG2226	methyltransferase
HUT19_RS21055	COG0745	RESPONSE REGULATOR receiver
HUT19_RS21060	COG2205	protein histidine kinase activity
HUT19_RS21070	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HUT19_RS21070	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HUT19_RS21075	COG0477	Major facilitator Superfamily
HUT19_RS21110	COG1191	sigma factor activity
HUT19_RS21115	COG1191	sigma factor activity
HUT19_RS21130	COG0205	6-phosphofructokinase activity
HUT19_RS21145	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HUT19_RS21150	COG0494	nUDIX hydrolase
HUT19_RS21160	COG1725	Transcriptional regulator
HUT19_RS21195	COG1674	ftsk spoiiie
HUT19_RS21250	COG0590	tRNA wobble adenosine to inosine editing
HUT19_RS21265	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HUT19_RS21280	COG0702	epimerase
HUT19_RS21290	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HUT19_RS21310	COG3594	Acyltransferase
HUT19_RS21370	COG1113	amino acid transport
HUT19_RS21385	COG0438	transferase activity, transferring glycosyl groups
HUT19_RS21395	COG0202	RNA polymerase activity
HUT19_RS21400	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HUT19_RS21410	COG2188	Transcriptional regulator
HUT19_RS21495	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HUT19_RS21500	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HUT19_RS21545	COG2124	cytochrome p450
HUT19_RS21610	COG1011	Hydrolase
HUT19_RS21650	COG1674	ftsk spoiiie
HUT19_RS21695	COG1408	metallophosphoesterase
HUT19_RS21705	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HUT19_RS21715	COG0003	Pfam Anion-transporting ATPase
HUT19_RS21740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUT19_RS21745	COG2826	transposase and inactivated derivatives, IS30 family
HUT19_RS21775	COG2267	carboxylic ester hydrolase activity
HUT19_RS21785	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HUT19_RS21790	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUT19_RS21795	COG0288	reversible hydration of carbon dioxide
HUT19_RS21855	COG1111	helicase
HUT19_RS21855	COG1205	dead DEAH box helicase
HUT19_RS21860	COG1366	Belongs to the anti-sigma-factor antagonist family
HUT19_RS21865	COG2172	sigma factor antagonist activity
HUT19_RS21870	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
HUT19_RS21880	COG2890	protein-(glutamine-N5) methyltransferase activity
HUT19_RS21890	COG1754	DNA topoisomerase type I activity
HUT19_RS21890	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HUT19_RS21895	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HUT19_RS21900	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HUT19_RS21920	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HUT19_RS21965	COG1674	ftsk spoiiie
HUT19_RS22005	COG1191	sigma factor activity
HUT19_RS22035	COG4585	Histidine kinase
HUT19_RS22040	COG2197	response regulator
HUT19_RS22045	COG2197	response regulator
HUT19_RS22095	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HUT19_RS22105	COG1595	DNA-templated transcription, initiation
HUT19_RS22125	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HUT19_RS22125	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HUT19_RS22150	COG1012	belongs to the aldehyde dehydrogenase family
HUT19_RS22155	COG2318	DinB family
HUT19_RS22180	COG0076	glutamate decarboxylase activity
HUT19_RS22190	COG0789	Transcriptional regulator
HUT19_RS22195	COG0586	Pfam SNARE associated Golgi protein
HUT19_RS22205	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HUT19_RS22210	COG2027	D-alanyl-D-alanine carboxypeptidase
HUT19_RS22220	COG0037	tRNA processing
HUT19_RS22235	COG0302	gtp cyclohydrolase
HUT19_RS22245	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HUT19_RS22250	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HUT19_RS22265	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HUT19_RS22265	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HUT19_RS22280	COG1174	glycine betaine transport
HUT19_RS22285	COG1174	glycine betaine transport
HUT19_RS22300	COG0649	NAD binding
HUT19_RS22315	COG2197	response regulator
HUT19_RS22320	COG0640	Transcriptional regulator
HUT19_RS22380	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HUT19_RS22385	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HUT19_RS22395	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HUT19_RS22415	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HUT19_RS22445	COG0737	Belongs to the 5'-nucleotidase family
HUT19_RS22450	COG0454	-acetyltransferase
HUT19_RS22450	COG0456	acetyltransferase
HUT19_RS22455	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HUT19_RS22475	COG0438	transferase activity, transferring glycosyl groups
HUT19_RS22505	COG0588	phosphoglycerate mutase activity
HUT19_RS22560	COG2188	Transcriptional regulator
HUT19_RS22595	COG1216	Glycosyl transferase, family 2
HUT19_RS22595	COG1442	glycosyl transferase family 8
HUT19_RS22605	COG1215	transferase activity, transferring glycosyl groups
HUT19_RS22615	COG5002	protein histidine kinase activity
HUT19_RS22625	COG2826	transposase and inactivated derivatives, IS30 family
HUT19_RS22635	COG1329	Transcriptional regulator
HUT19_RS22640	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
HUT19_RS22645	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
HUT19_RS22655	COG0215	cysteine-tRNA ligase activity
HUT19_RS22675	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HUT19_RS22685	COG3842	ATPase activity
HUT19_RS22695	COG4974	Belongs to the 'phage' integrase family
HUT19_RS22805	COG0582	viral genome integration into host DNA
HUT19_RS22825	COG0113	porphobilinogen synthase activity
HUT19_RS22830	COG0181	hydroxymethylbilane synthase activity
HUT19_RS22845	COG1309	transcriptional regulator
HUT19_RS22850	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUT19_RS22955	COG2124	cytochrome p450
HUT19_RS22960	COG1136	(ABC) transporter
HUT19_RS22960	COG0577	efflux transmembrane transporter activity
HUT19_RS22965	COG0577	efflux transmembrane transporter activity
HUT19_RS22965	COG1136	(ABC) transporter
HUT19_RS22975	COG2197	response regulator
HUT19_RS22995	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT19_RS23055	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUT19_RS23060	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUT19_RS23065	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUT19_RS23095	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HUT19_RS23100	COG1028	Short-chain dehydrogenase reductase Sdr
HUT19_RS23125	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HUT19_RS23130	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HUT19_RS23155	COG1414	Transcriptional regulator
HUT19_RS23160	COG3903	Transcriptional regulator
HUT19_RS23160	COG3629	intracellular signal transduction
HUT19_RS23195	COG1733	regulation of RNA biosynthetic process
HUT19_RS23225	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HUT19_RS23250	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HUT19_RS23285	COG0463	Glycosyl transferase, family 2
HUT19_RS23300	COG1278	Cold shock
HUT19_RS23305	COG0459	protein refolding
HUT19_RS23310	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HUT19_RS23315	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
HUT19_RS23350	COG0535	radical SAM domain protein
HUT19_RS23365	COG3142	Participates in the control of copper homeostasis
HUT19_RS23370	COG3973	AAA domain
HUT19_RS23410	COG1278	Cold shock
HUT19_RS23415	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
HUT19_RS23420	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HUT19_RS23430	COG2814	Major facilitator Superfamily
HUT19_RS23450	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HUT19_RS23460	COG2252	PERMEase
HUT19_RS23485	COG0667	Aldo Keto reductase
HUT19_RS23505	COG0277	FAD linked oxidase domain protein
HUT19_RS23505	COG0247	lactate metabolic process
HUT19_RS23520	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUT19_RS23525	COG4770	biotin carboxylase activity
HUT19_RS23535	COG0318	PFAM AMP-dependent synthetase and ligase
HUT19_RS23545	COG1309	transcriptional regulator
HUT19_RS23555	COG0259	pyridoxamine-phosphate oxidase activity
HUT19_RS23565	COG4821	SIS domain
HUT19_RS23575	COG2945	thiolester hydrolase activity
HUT19_RS23575	COG0596	Alpha beta hydrolase
HUT19_RS23650	COG1366	Belongs to the anti-sigma-factor antagonist family
HUT19_RS23655	COG3851	Histidine kinase
HUT19_RS23660	COG2197	response regulator
HUT19_RS23685	COG0515	serine threonine protein kinase
HUT19_RS23695	COG1012	belongs to the aldehyde dehydrogenase family
HUT19_RS23715	COG0519	Catalyzes the synthesis of GMP from XMP
HUT19_RS23715	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HUT19_RS23775	COG0515	serine threonine protein kinase
HUT19_RS23785	COG2197	response regulator
HUT19_RS23825	COG0460	homoserine dehydrogenase
HUT19_RS23860	COG0739	heme binding
HUT19_RS23870	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUT19_RS23885	COG0714	Associated with various cellular activities
HUT19_RS23895	COG3552	Protein containing von Willebrand factor type A (VWA) domain
HUT19_RS23910	COG0045	succinate-CoA ligase (ADP-forming) activity
HUT19_RS23935	COG0138	bifunctional purine biosynthesis protein purh
HUT19_RS23940	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HUT19_RS23955	COG0039	L-malate dehydrogenase activity
HUT19_RS23980	COG1012	belongs to the aldehyde dehydrogenase family
HUT19_RS23990	COG0517	IMP dehydrogenase activity
HUT19_RS23990	COG4175	Glycine betaine
HUT19_RS23995	COG4176	ABC-type proline glycine betaine transport system permease component
HUT19_RS24010	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUT19_RS24015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT19_RS24030	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HUT19_RS24040	COG0180	Tryptophanyl-tRNA synthetase
HUT19_RS24050	COG1295	ribonuclease BN
HUT19_RS24065	COG1408	metallophosphoesterase
HUT19_RS24095	COG0515	serine threonine protein kinase
HUT19_RS24095	COG2815	serine threonine protein kinase
HUT19_RS24100	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HUT19_RS24115	COG2009	succinate dehydrogenase
HUT19_RS24135	COG1595	DNA-templated transcription, initiation
HUT19_RS24150	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUT19_RS24150	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUT19_RS24155	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HUT19_RS24190	COG0726	polysaccharide deacetylase
HUT19_RS24195	COG1316	TRANSCRIPTIONal
HUT19_RS24215	COG4221	oxidoreductase activity
HUT19_RS24225	COG2186	Transcriptional regulator
HUT19_RS24230	COG3265	gluconokinase activity
HUT19_RS24245	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUT19_RS24270	COG1216	Glycosyl transferase, family 2
HUT19_RS24280	COG1083	cytidylyl-transferase
HUT19_RS24285	COG2089	acid synthase
HUT19_RS24295	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
HUT19_RS24295	COG1473	amidohydrolase
HUT19_RS24335	COG0583	DNA-binding transcription factor activity
HUT19_RS24340	COG2814	Major facilitator Superfamily
HUT19_RS24350	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HUT19_RS24380	COG2205	protein histidine kinase activity
HUT19_RS24385	COG0745	RESPONSE REGULATOR receiver
HUT19_RS24390	COG1595	DNA-templated transcription, initiation
HUT19_RS24405	COG1012	belongs to the aldehyde dehydrogenase family
HUT19_RS24410	COG1012	belongs to the aldehyde dehydrogenase family
HUT19_RS24425	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HUT19_RS24460	COG4770	biotin carboxylase activity
HUT19_RS24470	COG0424	maF-like protein
HUT19_RS24480	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUT19_RS24490	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
HUT19_RS24510	COG1024	Enoyl-CoA hydratase
HUT19_RS24520	COG2986	histidine ammonia-lyase
HUT19_RS24530	COG1376	ErfK ybiS ycfS ynhG family protein
HUT19_RS24610	COG1652	LysM domain
HUT19_RS24620	COG0148	phosphopyruvate hydratase activity
HUT19_RS24640	COG1252	NADH dehydrogenase
HUT19_RS24645	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HUT19_RS24650	COG0577	efflux transmembrane transporter activity
HUT19_RS24655	COG1136	(ABC) transporter
HUT19_RS24685	COG0183	Belongs to the thiolase family
HUT19_RS24690	COG2755	lipolytic protein G-D-S-L family
HUT19_RS24705	COG0318	PFAM AMP-dependent synthetase and ligase
HUT19_RS24710	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HUT19_RS24755	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HUT19_RS24770	COG1228	amidohydrolase
HUT19_RS24775	COG1191	sigma factor activity
HUT19_RS24780	COG1366	Belongs to the anti-sigma-factor antagonist family
HUT19_RS24815	COG0745	RESPONSE REGULATOR receiver
HUT19_RS24820	COG2205	protein histidine kinase activity
HUT19_RS24835	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HUT19_RS24845	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HUT19_RS24855	COG3344	reverse transcriptase
HUT19_RS24885	COG1316	TRANSCRIPTIONal
HUT19_RS24900	COG1316	TRANSCRIPTIONal
HUT19_RS24915	COG1316	TRANSCRIPTIONal
HUT19_RS24920	COG1316	TRANSCRIPTIONal
HUT19_RS24940	COG2124	cytochrome p450
HUT19_RS24955	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT19_RS24975	COG0300	oxidoreductase activity
HUT19_RS24985	COG0778	Nitroreductase
HUT19_RS24985	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
HUT19_RS24990	COG0391	Required for morphogenesis under gluconeogenic growth conditions
HUT19_RS25025	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HUT19_RS25030	COG2835	tetraacyldisaccharide 4'-kinase activity
HUT19_RS25040	COG1482	cell wall glycoprotein biosynthetic process
HUT19_RS25050	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HUT19_RS25050	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HUT19_RS25050	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUT19_RS25055	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HUT19_RS25085	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HUT19_RS25090	COG0745	RESPONSE REGULATOR receiver
HUT19_RS25095	COG5002	protein histidine kinase activity
HUT19_RS25100	COG0823	Involved in the tonB-independent uptake of proteins
HUT19_RS25110	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HUT19_RS25115	COG2197	response regulator
HUT19_RS25120	COG3214	Protein conserved in bacteria
HUT19_RS25130	COG0653	protein targeting
HUT19_RS25145	COG0546	phosphoglycolate phosphatase activity
HUT19_RS25150	COG0693	protein deglycase activity
HUT19_RS25155	COG2902	Dehydrogenase
HUT19_RS25160	COG1215	transferase activity, transferring glycosyl groups
HUT19_RS25185	COG0438	transferase activity, transferring glycosyl groups
HUT19_RS25240	COG0395	ABC-type sugar transport system, permease component
HUT19_RS25260	COG0515	serine threonine protein kinase
HUT19_RS25265	COG0515	serine threonine protein kinase
HUT19_RS25270	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HUT19_RS25285	COG2884	Cell division ATP-binding protein ftsE
HUT19_RS25295	COG0793	Belongs to the peptidase S41A family
HUT19_RS25300	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HUT19_RS25310	COG3344	reverse transcriptase
HUT19_RS25325	COG2027	D-alanyl-D-alanine carboxypeptidase
HUT19_RS25340	COG0583	DNA-binding transcription factor activity
HUT19_RS25345	COG2223	nitrite transmembrane transporter activity
HUT19_RS25365	COG3973	AAA domain
HUT19_RS25370	COG1278	Cold shock
HUT19_RS25380	COG0776	regulation of translation
HUT19_RS25385	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HUT19_RS25390	COG1678	Uncharacterized ACR, COG1678
HUT19_RS25410	COG1175	transmembrane transport
HUT19_RS25415	COG0395	ABC-type sugar transport system, permease component
HUT19_RS25420	COG3525	Glycosyl hydrolase, family 20, catalytic domain
HUT19_RS25530	COG2855	membrane
HUT19_RS25570	COG3185	4-Hydroxyphenylpyruvate dioxygenase
HUT19_RS25580	COG0277	FAD linked oxidase domain protein
HUT19_RS25610	COG2186	Transcriptional regulator
HUT19_RS25680	COG1335	isochorismatase
HUT19_RS25690	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
HUT19_RS25700	COG1113	amino acid transport
HUT19_RS25720	COG1234	tRNA 3'-trailer cleavage
HUT19_RS25725	COG1263	PTS System
HUT19_RS25730	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUT19_RS25735	COG2826	transposase and inactivated derivatives, IS30 family
HUT19_RS25740	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HUT19_RS25750	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HUT19_RS25770	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HUT19_RS25775	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HUT19_RS25800	COG2733	membrane
HUT19_RS25805	COG3764	Sortase (surface protein transpeptidase)
HUT19_RS25815	COG0706	membrane insertase activity
HUT19_RS25825	COG4702	Belongs to the UPF0303 family
HUT19_RS25830	COG0673	inositol 2-dehydrogenase activity
HUT19_RS25880	COG2186	Transcriptional regulator
HUT19_RS25910	COG3397	chitin binding
HUT19_RS25935	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUT19_RS25940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUT19_RS25945	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HUT19_RS25955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT19_RS25960	COG1063	alcohol dehydrogenase
HUT19_RS25965	COG0477	Major facilitator Superfamily
HUT19_RS25975	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUT19_RS25980	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUT19_RS26000	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUT19_RS26010	COG1028	Short-chain dehydrogenase reductase Sdr
HUT19_RS26035	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HUT19_RS26040	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUT19_RS26045	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HUT19_RS26050	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HUT19_RS26055	COG1028	Short-chain dehydrogenase reductase Sdr
HUT19_RS26070	COG4770	biotin carboxylase activity
HUT19_RS26100	COG1126	abc transporter atp-binding protein
HUT19_RS26105	COG0765	amino acid transport
HUT19_RS26110	COG0765	amino acid transport
HUT19_RS26115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUT19_RS26125	COG0154	amidase activity
HUT19_RS26160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT19_RS26180	COG2197	response regulator
HUT19_RS26185	COG4585	Histidine kinase
HUT19_RS26205	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
HUT19_RS26225	COG1028	Short-chain dehydrogenase reductase Sdr
HUT19_RS26270	COG0406	alpha-ribazole phosphatase activity
HUT19_RS26310	COG3979	chitinase
HUT19_RS26315	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HUT19_RS26345	COG1215	transferase activity, transferring glycosyl groups
HUT19_RS26375	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HUT19_RS26380	COG4977	sequence-specific DNA binding
HUT19_RS26390	COG0589	response to stress
HUT19_RS26395	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HUT19_RS26415	COG1960	acyl-CoA dehydrogenase activity
HUT19_RS26430	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUT19_RS26435	COG1309	transcriptional regulator
HUT19_RS26445	COG1946	Acyl-CoA thioesterase
HUT19_RS26455	COG1278	Cold shock
HUT19_RS26510	COG1472	Belongs to the glycosyl hydrolase 3 family
HUT19_RS26530	COG2264	protein methyltransferase activity
HUT19_RS26535	COG1609	Transcriptional regulator
HUT19_RS26540	COG0673	inositol 2-dehydrogenase activity
HUT19_RS26575	COG1869	D-ribose catabolic process
HUT19_RS26580	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUT19_RS26585	COG1879	ABC-type sugar transport system periplasmic component
HUT19_RS26590	COG1129	ABC transporter
HUT19_RS26595	COG1609	Transcriptional regulator
HUT19_RS26600	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HUT19_RS26625	COG2409	Drug exporters of the RND superfamily
HUT19_RS26640	COG0673	inositol 2-dehydrogenase activity
HUT19_RS26665	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUT19_RS26675	COG3718	enzyme involved in inositol metabolism
HUT19_RS26680	COG3962	Belongs to the TPP enzyme family
HUT19_RS26705	COG3226	Transcriptional regulator
HUT19_RS26720	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HUT19_RS26725	COG1053	succinate dehydrogenase
HUT19_RS26735	COG0583	DNA-binding transcription factor activity
HUT19_RS26740	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HUT19_RS26745	COG1993	acr, cog1993
HUT19_RS26750	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HUT19_RS26755	COG0142	geranyltranstransferase activity
HUT19_RS26760	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HUT19_RS26780	COG0017	Asparaginyl-tRNA synthetase
HUT19_RS26790	COG2226	methyltransferase
HUT19_RS26795	COG1619	proteins homologs of microcin C7 resistance protein MccF
HUT19_RS26815	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HUT19_RS26850	COG2264	protein methyltransferase activity
HUT19_RS26890	COG0741	lytic transglycosylase activity
HUT19_RS26940	COG0629	single-stranded DNA binding
HUT19_RS26970	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HUT19_RS27000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUT19_RS27020	COG1486	melibiose metabolic process
HUT19_RS27025	COG0395	ABC-type sugar transport system, permease component
HUT19_RS27030	COG1175	transmembrane transport
HUT19_RS27040	COG1940	carbohydrate kinase activity
HUT19_RS27040	COG1846	Transcriptional regulator
HUT19_RS27045	COG0668	transmembrane transport
HUT19_RS27075	COG3344	reverse transcriptase
HUT19_RS27110	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
HUT19_RS27115	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HUT19_RS27120	COG1113	amino acid transport
HUT19_RS27125	COG1268	BioY protein
HUT19_RS27130	COG1113	amino acid transport
HUT19_RS27145	COG4552	Acetyltransferase involved in intracellular survival and related
HUT19_RS27155	COG3594	Acyltransferase
HUT19_RS27175	COG0544	peptidyl-prolyl cis-trans isomerase activity
HUT19_RS27180	COG0740	serine-type endopeptidase activity
HUT19_RS27185	COG0740	serine-type endopeptidase activity
HUT19_RS27190	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HUT19_RS27210	COG0525	valine-tRNA ligase activity
HUT19_RS27215	COG0768	penicillin binding
HUT19_RS27220	COG0285	dihydrofolate synthase activity
HUT19_RS27230	COG0105	UTP biosynthetic process
HUT19_RS27235	COG1077	Cell shape determining protein MreB Mrl
HUT19_RS27250	COG0768	penicillin binding
HUT19_RS27255	COG0772	Belongs to the SEDS family
HUT19_RS27275	COG1530	ribonuclease E activity
HUT19_RS27280	COG0261	This protein binds to 23S rRNA in the presence of protein L20
HUT19_RS27285	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HUT19_RS27290	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HUT19_RS27300	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HUT19_RS27310	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HUT19_RS27325	COG0501	Belongs to the peptidase M48B family
HUT19_RS27340	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HUT19_RS27350	COG0799	negative regulation of ribosome biogenesis
HUT19_RS27355	COG0588	phosphoglycerate mutase activity
HUT19_RS27370	COG0477	Major facilitator Superfamily
HUT19_RS27390	COG0495	leucyl-tRNA aminoacylation
HUT19_RS27400	COG1307	EDD domain protein, DegV family
HUT19_RS27405	COG1555	photosystem II stabilization
HUT19_RS27430	COG4122	O-methyltransferase activity
HUT19_RS27450	COG0268	Binds directly to 16S ribosomal RNA
HUT19_RS27455	COG0481	GTPase activity
HUT19_RS27460	COG1022	Amp-dependent synthetase and ligase
HUT19_RS27490	COG1420	regulation of RNA biosynthetic process
HUT19_RS27495	COG0484	heat shock protein binding
HUT19_RS27515	COG0537	adenosine 5'-monophosphoramidase activity
HUT19_RS27520	COG1234	tRNA 3'-trailer cleavage
HUT19_RS27525	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUT19_RS27535	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HUT19_RS27565	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HUT19_RS27580	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HUT19_RS27590	COG2409	Drug exporters of the RND superfamily
HUT19_RS27595	COG4585	Histidine kinase
HUT19_RS27600	COG2197	response regulator
HUT19_RS27640	COG0456	acetyltransferase
HUT19_RS27640	COG0454	-acetyltransferase
HUT19_RS27650	COG1381	Involved in DNA repair and RecF pathway recombination
HUT19_RS27655	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HUT19_RS27660	COG0247	lactate metabolic process
HUT19_RS27665	COG0277	FAD linked oxidase domain protein
HUT19_RS27670	COG1620	l-lactate permease
HUT19_RS27675	COG2186	Transcriptional regulator
HUT19_RS27725	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HUT19_RS27730	COG1121	(ABC) transporter
HUT19_RS27740	COG0423	glycine-tRNA ligase activity
HUT19_RS27760	COG0667	Aldo Keto reductase
HUT19_RS27765	COG0477	Major facilitator Superfamily
HUT19_RS27790	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HUT19_RS27790	COG0574	Belongs to the PEP-utilizing enzyme family
HUT19_RS27800	COG0395	ABC-type sugar transport system, permease component
HUT19_RS27805	COG1175	transmembrane transport
HUT19_RS27820	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HUT19_RS27825	COG3485	protocatechuate 3,4-dioxygenase
HUT19_RS27830	COG3485	protocatechuate 3,4-dioxygenase
HUT19_RS27835	COG0183	Belongs to the thiolase family
HUT19_RS27840	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HUT19_RS27845	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HUT19_RS27855	COG2890	protein-(glutamine-N5) methyltransferase activity
HUT19_RS27890	COG2146	nitrite reductase [NAD(P)H] activity
HUT19_RS27890	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HUT19_RS27895	COG2146	nitrite reductase [NAD(P)H] activity
HUT19_RS27895	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HUT19_RS27900	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HUT19_RS27940	COG0745	RESPONSE REGULATOR receiver
HUT19_RS27950	COG3344	reverse transcriptase
HUT19_RS27980	COG2949	membrane
HUT19_RS27985	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HUT19_RS27995	COG0243	molybdopterin cofactor binding
HUT19_RS28005	COG0232	Belongs to the dGTPase family. Type 2 subfamily
HUT19_RS28020	COG0358	DNA primase activity
HUT19_RS28025	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HUT19_RS28030	COG1070	Carbohydrate kinase
HUT19_RS28060	COG1028	Short-chain dehydrogenase reductase Sdr
HUT19_RS28065	COG0583	DNA-binding transcription factor activity
HUT19_RS28110	COG2197	response regulator
HUT19_RS28115	COG4585	Histidine kinase
HUT19_RS28125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HUT19_RS28130	COG0588	phosphoglycerate mutase activity
HUT19_RS28145	COG3386	PFAM SMP-30 Gluconolaconase
HUT19_RS28160	COG2130	NADP-dependent
HUT19_RS28190	COG4221	oxidoreductase activity
HUT19_RS28235	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUT19_RS28240	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUT19_RS28245	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUT19_RS28270	COG0789	Transcriptional regulator
HUT19_RS28305	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HUT19_RS28310	COG0300	oxidoreductase activity
HUT19_RS28315	COG2197	response regulator
HUT19_RS28320	COG4585	Histidine kinase
HUT19_RS28335	COG1309	transcriptional regulator
HUT19_RS28340	COG0477	Major facilitator Superfamily
HUT19_RS28370	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HUT19_RS28415	COG1358	cellular component organization or biogenesis
HUT19_RS28450	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HUT19_RS28500	COG2304	oxidoreductase activity
HUT19_RS28560	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUT19_RS28615	COG1028	Short-chain dehydrogenase reductase Sdr
HUT19_RS28645	COG2207	Transcriptional regulator
HUT19_RS28660	COG2124	cytochrome p450
HUT19_RS28665	COG0183	Belongs to the thiolase family
HUT19_RS28675	COG3845	ABC transporter
HUT19_RS28715	COG2197	response regulator
HUT19_RS28720	COG1309	transcriptional regulator
HUT19_RS28725	COG0438	transferase activity, transferring glycosyl groups
HUT19_RS28745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT19_RS28755	COG0860	N-Acetylmuramoyl-L-alanine amidase
HUT19_RS28770	COG2197	response regulator
HUT19_RS28775	COG4585	Histidine kinase
HUT19_RS28780	COG2030	dehydratase
HUT19_RS28785	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
HUT19_RS28790	COG1028	Short-chain dehydrogenase reductase Sdr
HUT19_RS28795	COG3800	Transcriptional regulator
HUT19_RS28795	COG1396	sequence-specific DNA binding
HUT19_RS28820	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HUT19_RS28835	COG0800	Aldolase
HUT19_RS28840	COG3022	response to hydroperoxide
HUT19_RS28845	COG0366	Alpha amylase catalytic
HUT19_RS28865	COG1609	Transcriptional regulator
HUT19_RS28870	COG0789	Transcriptional regulator
HUT19_RS28970	COG1122	ATPase activity
HUT19_RS29040	COG1672	PFAM Archaeal ATPase
HUT19_RS29040	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
HUT19_RS29050	COG2814	Major facilitator Superfamily
HUT19_RS29060	COG0151	Belongs to the GarS family
HUT19_RS29070	COG2340	Cysteine-rich secretory protein family
HUT19_RS29115	COG3540	Alkaline phosphatase
HUT19_RS29120	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HUT19_RS29150	COG0672	)-iron permease
HUT19_RS29155	COG2837	iron assimilation
HUT19_RS29165	COG1120	ATPase activity
HUT19_RS29225	COG1175	transmembrane transport
HUT19_RS29230	COG0395	ABC-type sugar transport system, permease component
HUT19_RS29245	COG1994	Peptidase M50
HUT19_RS29270	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
HUT19_RS29275	COG0477	Major facilitator Superfamily
HUT19_RS29280	COG1309	transcriptional regulator
HUT19_RS29290	COG2814	Major facilitator Superfamily
HUT19_RS29295	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HUT19_RS29295	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HUT19_RS29300	COG2132	Multicopper oxidase
HUT19_RS29305	COG0174	glutamine synthetase
HUT19_RS29310	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HUT19_RS29380	COG2188	Transcriptional regulator
HUT19_RS29385	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HUT19_RS29395	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
HUT19_RS29405	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
HUT19_RS29410	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
HUT19_RS29430	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
HUT19_RS29455	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HUT19_RS29470	COG1609	Transcriptional regulator
HUT19_RS29475	COG0366	Alpha amylase catalytic
HUT19_RS29480	COG2182	Extracellular solute-binding protein
HUT19_RS29485	COG1175	transmembrane transport
HUT19_RS29490	COG3833	ABC-type maltose transport systems, permease component
HUT19_RS29495	COG0366	Alpha amylase catalytic
HUT19_RS29520	COG2197	response regulator
HUT19_RS29545	COG0745	RESPONSE REGULATOR receiver
HUT19_RS29575	COG0477	Major facilitator Superfamily
HUT19_RS29605	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HUT19_RS29615	COG0174	glutamine synthetase
HUT19_RS29635	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HUT19_RS29640	COG0321	lipoyl(octanoyl) transferase activity
HUT19_RS29680	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HUT19_RS29690	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUT19_RS29695	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HUT19_RS29700	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HUT19_RS29715	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HUT19_RS29715	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HUT19_RS29720	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
HUT19_RS29755	COG4585	Histidine kinase
HUT19_RS29760	COG2197	response regulator
HUT19_RS29765	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HUT19_RS29785	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUT19_RS29795	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HUT19_RS29800	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HUT19_RS29810	COG1376	ErfK ybiS ycfS ynhG family protein
HUT19_RS29820	COG1845	cytochrome c oxidase, subunit III
HUT19_RS29825	COG2010	Cytochrome c
HUT19_RS29830	COG0723	plastoquinol--plastocyanin reductase activity
HUT19_RS29835	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HUT19_RS29840	COG2826	transposase and inactivated derivatives, IS30 family
HUT19_RS29845	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HUT19_RS29850	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HUT19_RS29875	COG0791	NLP P60 protein
HUT19_RS29880	COG0791	NLP P60 protein
HUT19_RS29890	COG0438	transferase activity, transferring glycosyl groups
HUT19_RS29910	COG0003	Pfam Anion-transporting ATPase
HUT19_RS29920	COG1940	carbohydrate kinase activity
HUT19_RS29955	COG2197	response regulator
HUT19_RS29960	COG0205	6-phosphofructokinase activity
HUT19_RS30030	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
HUT19_RS30035	COG0243	molybdopterin cofactor binding
HUT19_RS30040	COG2193	ferroxidase activity
HUT19_RS30045	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HUT19_RS30055	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HUT19_RS30060	COG0515	serine threonine protein kinase
HUT19_RS30060	COG2815	serine threonine protein kinase
HUT19_RS30070	COG2022	thiamine diphosphate biosynthetic process
HUT19_RS30080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUT19_RS30080	COG2022	thiamine diphosphate biosynthetic process
HUT19_RS30085	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HUT19_RS30095	COG0352	thiamine-phosphate diphosphorylase activity
HUT19_RS30110	COG1233	COG1233 Phytoene dehydrogenase and related
HUT19_RS30115	COG1309	transcriptional regulator
HUT19_RS30125	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
HUT19_RS30135	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HUT19_RS30155	COG0714	Associated with various cellular activities
HUT19_RS30165	COG0275	rRNA processing
HUT19_RS30175	COG0768	penicillin binding
HUT19_RS30180	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HUT19_RS30185	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HUT19_RS30190	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HUT19_RS30195	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HUT19_RS30205	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HUT19_RS30210	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HUT19_RS30215	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HUT19_RS30230	COG1799	cell septum assembly
HUT19_RS30245	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HUT19_RS30255	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HUT19_RS30305	COG0587	DNA-directed DNA polymerase activity
HUT19_RS30315	COG1432	Conserved Protein
HUT19_RS30345	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HUT19_RS30355	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HUT19_RS30360	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HUT19_RS30365	COG0131	Imidazoleglycerol-phosphate dehydratase
HUT19_RS30375	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HUT19_RS30380	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HUT19_RS30385	COG0251	oxidation-reduction process
HUT19_RS30390	COG0107	imidazoleglycerol-phosphate synthase activity
HUT19_RS30435	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HUT19_RS30440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HUT19_RS30460	COG0134	indole-3-glycerol-phosphate synthase activity
HUT19_RS30465	COG0133	tryptophan synthase activity
HUT19_RS30470	COG0159	tryptophan synthase activity
HUT19_RS30480	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HUT19_RS30490	COG0069	glutamate synthase activity
HUT19_RS30490	COG0067	glutamate synthase
HUT19_RS30490	COG0070	glutamate synthase
HUT19_RS30505	COG3467	pyridoxamine 5'-phosphate
HUT19_RS30525	COG0287	Prephenate dehydrogenase
HUT19_RS30525	COG1605	Chorismate mutase
HUT19_RS30550	COG0737	Belongs to the 5'-nucleotidase family
HUT19_RS30590	COG0411	ABC transporter
HUT19_RS30615	COG2050	protein possibly involved in aromatic compounds catabolism
HUT19_RS30660	COG1643	Atp-dependent helicase
HUT19_RS30665	COG2226	methyltransferase
HUT19_RS30670	COG0539	negative regulation of cytoplasmic translation
HUT19_RS30685	COG0237	dephospho-CoA kinase activity
HUT19_RS30705	COG1309	transcriptional regulator
HUT19_RS30745	COG0584	glycerophosphoryl diester phosphodiesterase
HUT19_RS30755	COG0556	nucleotide-excision repair
HUT19_RS30775	COG0477	Major facilitator Superfamily
HUT19_RS30785	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HUT19_RS30795	COG1609	Transcriptional regulator
HUT19_RS30805	COG0322	excinuclease ABC activity
HUT19_RS30810	COG1660	Displays ATPase and GTPase activities
HUT19_RS30815	COG0391	Required for morphogenesis under gluconeogenic growth conditions
HUT19_RS30820	COG1481	regulation of sporulation
HUT19_RS30830	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HUT19_RS30835	COG0126	phosphoglycerate kinase activity
HUT19_RS30840	COG0149	triose-phosphate isomerase activity
HUT19_RS30845	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HUT19_RS30860	COG0166	Belongs to the GPI family
HUT19_RS30865	COG0363	glucosamine-6-phosphate deaminase activity
HUT19_RS30880	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HUT19_RS30885	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HUT19_RS30890	COG0109	protoheme IX farnesyltransferase activity
HUT19_RS30905	COG1612	heme a metabolic process
HUT19_RS30940	COG0396	ATPase activity
HUT19_RS30945	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HUT19_RS30950	COG0822	iron-sulfur transferase activity
HUT19_RS30960	COG2076	Multidrug Resistance protein
HUT19_RS30965	COG3226	Transcriptional regulator
HUT19_RS30970	COG2171	N-acyltransferase activity
HUT19_RS30975	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUT19_RS31000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT19_RS31025	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUT19_RS31030	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUT19_RS31055	COG0667	Aldo Keto reductase
HUT19_RS31065	COG4585	Histidine kinase
HUT19_RS31085	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HUT19_RS31090	COG5285	phytanoyl-CoA dioxygenase
HUT19_RS31095	COG1917	Cupin 2, conserved barrel domain protein
HUT19_RS31105	COG0456	acetyltransferase
HUT19_RS31135	COG1797	cobyrinic acid a,c-diamide synthase activity
HUT19_RS31150	COG1492	cobalamin metabolic process
HUT19_RS31155	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HUT19_RS31170	COG0235	Class ii aldolase
HUT19_RS31190	COG0488	(ABC) transporter
HUT19_RS31210	COG2205	protein histidine kinase activity
HUT19_RS31210	COG0784	Response regulator, receiver
HUT19_RS31225	COG1302	Protein conserved in bacteria
HUT19_RS31250	COG1028	Short-chain dehydrogenase reductase Sdr
HUT19_RS31255	COG3387	PFAM Glycoside hydrolase 15-related
HUT19_RS31270	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HUT19_RS31290	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUT19_RS31295	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HUT19_RS31315	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HUT19_RS31370	COG1028	Short-chain dehydrogenase reductase Sdr
HUT19_RS31375	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HUT19_RS31385	COG2186	Transcriptional regulator
HUT19_RS31390	COG2807	transmembrane transport
HUT19_RS31405	COG3830	Belongs to the UPF0237 family
HUT19_RS31405	COG0560	Phosphoserine phosphatase
HUT19_RS31415	COG1131	(ABC) transporter
HUT19_RS31415	COG0842	Transport permease protein
HUT19_RS31415	COG1716	ATPase activity
HUT19_RS31430	COG2197	response regulator
HUT19_RS31445	COG1119	ATPase activity
HUT19_RS31465	COG1881	PFAM PEBP family protein
HUT19_RS31480	COG2094	Belongs to the DNA glycosylase MPG family
HUT19_RS31515	COG0647	UMP catabolic process
HUT19_RS31520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT19_RS31525	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT19_RS31550	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HUT19_RS31555	COG0497	DNA recombination
HUT19_RS31560	COG0297	glycogen (starch) synthase activity
HUT19_RS31575	COG3387	PFAM Glycoside hydrolase 15-related
HUT19_RS31580	COG0504	CTP synthase activity
HUT19_RS31585	COG0494	nUDIX hydrolase
HUT19_RS31595	COG0686	Belongs to the AlaDH PNT family
HUT19_RS31610	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HUT19_RS31615	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HUT19_RS31620	COG1187	pseudouridine synthase activity
HUT19_RS31635	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
HUT19_RS31645	COG1160	GTP binding
HUT19_RS31660	COG0438	transferase activity, transferring glycosyl groups
HUT19_RS31670	COG0596	Alpha beta hydrolase
HUT19_RS31680	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HUT19_RS31730	COG0671	phosphoesterase, PA-phosphatase related
HUT19_RS31740	COG0477	Major facilitator Superfamily
HUT19_RS31745	COG1960	acyl-CoA dehydrogenase activity
HUT19_RS31750	COG1799	cell septum assembly
HUT19_RS31780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT19_RS31785	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT19_RS31795	COG0330	HflC and HflK could
HUT19_RS31810	COG3467	pyridoxamine 5'-phosphate
HUT19_RS31815	COG0587	DNA-directed DNA polymerase activity
HUT19_RS31820	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HUT19_RS31840	COG1764	response to oxidative stress
HUT19_RS31845	COG1846	Transcriptional regulator
HUT19_RS31865	COG2409	Drug exporters of the RND superfamily
HUT19_RS31875	COG0640	Transcriptional regulator
HUT19_RS31895	COG4264	IucA IucC family
HUT19_RS31900	COG0019	diaminopimelate decarboxylase activity
HUT19_RS31960	COG1725	Transcriptional regulator
HUT19_RS31965	COG1834	amidinotransferase
HUT19_RS31980	COG2755	lipolytic protein G-D-S-L family
HUT19_RS31985	COG0515	serine threonine protein kinase
HUT19_RS31990	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
HUT19_RS32030	COG2188	Transcriptional regulator
HUT19_RS32035	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
HUT19_RS32040	COG1309	transcriptional regulator
HUT19_RS32045	COG3383	formate dehydrogenase (NAD+) activity
HUT19_RS32050	COG2851	Citrate transporter
HUT19_RS32105	COG1960	acyl-CoA dehydrogenase activity
HUT19_RS32150	COG0318	PFAM AMP-dependent synthetase and ligase
HUT19_RS32155	COG1309	transcriptional regulator
HUT19_RS32180	COG2149	membrane
HUT19_RS32185	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
HUT19_RS32215	COG0438	transferase activity, transferring glycosyl groups
HUT19_RS32225	COG0702	epimerase
HUT19_RS32235	COG1733	regulation of RNA biosynthetic process
HUT19_RS32290	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HUT19_RS32295	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HUT19_RS32300	COG2080	2 iron, 2 sulfur cluster binding
HUT19_RS32330	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUT19_RS32335	COG1402	creatininase
HUT19_RS32350	COG0438	transferase activity, transferring glycosyl groups
HUT19_RS32370	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HUT19_RS32415	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUT19_RS32440	COG0667	Aldo Keto reductase
HUT19_RS32445	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT19_RS32455	COG0598	Magnesium transport protein CorA
HUT19_RS32460	COG0406	alpha-ribazole phosphatase activity
HUT19_RS32475	COG0215	cysteine-tRNA ligase activity
HUT19_RS32490	COG1028	Short-chain dehydrogenase reductase Sdr
HUT19_RS32500	COG1129	ABC transporter
HUT19_RS32505	COG4211	Belongs to the binding-protein-dependent transport system permease family
HUT19_RS32520	COG2186	Transcriptional regulator
HUT19_RS32530	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HUT19_RS32535	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HUT19_RS32540	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HUT19_RS32545	COG1414	Transcriptional regulator
HUT19_RS32550	COG1410	methionine synthase
HUT19_RS32550	COG0646	methionine synthase
HUT19_RS32555	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUT19_RS32570	COG2197	response regulator
HUT19_RS32580	COG1994	Peptidase M50
HUT19_RS32580	COG0517	IMP dehydrogenase activity
HUT19_RS32600	COG1222	aaa ATPase
HUT19_RS32605	COG4122	O-methyltransferase activity
HUT19_RS32615	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
HUT19_RS32620	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
HUT19_RS32625	COG1609	Transcriptional regulator
HUT19_RS32635	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
HUT19_RS32650	COG2378	regulation of single-species biofilm formation
HUT19_RS32670	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HUT19_RS32675	COG0805	protein transport
HUT19_RS32695	COG2826	transposase and inactivated derivatives, IS30 family
HUT19_RS32705	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HUT19_RS32710	COG4175	Glycine betaine
HUT19_RS32710	COG0517	IMP dehydrogenase activity
HUT19_RS32715	COG4176	ABC-type proline glycine betaine transport system permease component
HUT19_RS32725	COG0667	Aldo Keto reductase
HUT19_RS32750	COG1228	amidohydrolase
HUT19_RS32755	COG2267	carboxylic ester hydrolase activity
HUT19_RS32760	COG3958	Transketolase
HUT19_RS32765	COG3959	Transketolase, thiamine diphosphate binding domain
HUT19_RS32770	COG0789	Transcriptional regulator
HUT19_RS32835	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HUT19_RS32840	COG0698	ribose 5-phosphate isomerase
HUT19_RS32875	COG2376	Dihydroxyacetone kinase
HUT19_RS32940	COG2255	four-way junction helicase activity
HUT19_RS32975	COG3328	transposase activity
HUT19_RS33165	COG3328	transposase activity
HUT19_RS33185	COG4249	Peptidase C14 caspase catalytic subunit p20
HUT19_RS33185	COG2319	Wd-40 repeat
HUT19_RS33195	COG2801	Transposase and inactivated derivatives
HUT19_RS33220	COG3328	transposase activity
HUT19_RS33245	COG0604	alcohol dehydrogenase
HUT19_RS33250	COG0183	Belongs to the thiolase family
HUT19_RS33255	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUT19_RS33275	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUT19_RS33325	COG4106	trans-aconitate 2-methyltransferase activity
HUT19_RS33330	COG2197	response regulator
HUT19_RS33350	COG2340	Cysteine-rich secretory protein family
HUT19_RS33375	COG2860	membrane
HUT19_RS33385	COG1404	Belongs to the peptidase S8 family
HUT19_RS33390	COG1674	ftsk spoiiie
HUT19_RS33455	COG2390	Transcriptional regulator
HUT19_RS33470	COG1309	transcriptional regulator
HUT19_RS33475	COG2390	Transcriptional regulator
HUT19_RS33490	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HUT19_RS33515	COG1309	transcriptional regulator
HUT19_RS33540	COG0604	alcohol dehydrogenase
HUT19_RS33555	COG4221	oxidoreductase activity
HUT19_RS33560	COG1028	Short-chain dehydrogenase reductase Sdr
HUT19_RS33595	COG1024	Enoyl-CoA hydratase
HUT19_RS33600	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUT19_RS33615	COG0583	DNA-binding transcription factor activity
HUT19_RS33645	COG0601	transmembrane transport
HUT19_RS33650	COG0747	negative chemotaxis
HUT19_RS33665	COG4948	Mandelate Racemase Muconate Lactonizing
HUT19_RS33670	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HUT19_RS33680	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HUT19_RS33685	COG0596	Alpha beta hydrolase
HUT19_RS33700	COG1121	(ABC) transporter
HUT19_RS33705	COG0803	Belongs to the bacterial solute-binding protein 9 family
HUT19_RS33715	COG0523	cobalamin synthesis protein
HUT19_RS33730	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HUT19_RS33735	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HUT19_RS33740	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HUT19_RS33745	COG0254	rRNA binding
HUT19_RS33755	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HUT19_RS33760	COG0701	Predicted permease
HUT19_RS33775	COG1846	Transcriptional regulator
HUT19_RS33780	COG0038	chloride channel
HUT19_RS33800	COG2208	phosphoserine phosphatase activity
HUT19_RS33800	COG2770	Histidine kinase
HUT19_RS33880	COG2018	Roadblock/LC7 domain
HUT19_RS33920	COG1620	l-lactate permease
HUT19_RS33925	COG2186	Transcriptional regulator
HUT19_RS34020	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUT19_RS34030	COG3962	Belongs to the TPP enzyme family
HUT19_RS34035	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HUT19_RS34050	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HUT19_RS34055	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
HUT19_RS34065	COG1215	transferase activity, transferring glycosyl groups
HUT19_RS34075	COG4310	Domain of unknown function (DUF2172)
HUT19_RS34090	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HUT19_RS34100	COG0438	transferase activity, transferring glycosyl groups
HUT19_RS34145	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HUT19_RS34150	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HUT19_RS34160	COG0477	Major facilitator Superfamily
HUT19_RS34235	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUT19_RS34285	COG1454	alcohol dehydrogenase
HUT19_RS34295	COG1012	belongs to the aldehyde dehydrogenase family
HUT19_RS34300	COG4948	Mandelate Racemase Muconate Lactonizing
HUT19_RS34305	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
HUT19_RS34320	COG0477	Major facilitator Superfamily
HUT19_RS34325	COG0596	Alpha beta hydrolase
HUT19_RS34335	COG4977	sequence-specific DNA binding
HUT19_RS34345	COG1960	acyl-CoA dehydrogenase activity
HUT19_RS34365	COG1063	alcohol dehydrogenase
HUT19_RS34370	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HUT19_RS34375	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT19_RS34380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT19_RS34400	COG0243	molybdopterin cofactor binding
HUT19_RS34410	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HUT19_RS34435	COG0765	amino acid transport
HUT19_RS34445	COG0583	DNA-binding transcription factor activity
HUT19_RS34475	COG0183	Belongs to the thiolase family
HUT19_RS34485	COG0318	PFAM AMP-dependent synthetase and ligase
HUT19_RS34490	COG1309	transcriptional regulator
HUT19_RS34495	COG1028	Short-chain dehydrogenase reductase Sdr
HUT19_RS34515	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUT19_RS34525	COG0318	PFAM AMP-dependent synthetase and ligase
HUT19_RS34550	COG1024	Enoyl-CoA hydratase
HUT19_RS34560	COG0583	DNA-binding transcription factor activity
HUT19_RS34570	COG1028	Short-chain dehydrogenase reductase Sdr
HUT19_RS34575	COG2130	NADP-dependent
HUT19_RS34585	COG1309	transcriptional regulator
HUT19_RS34590	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HUT19_RS34610	COG3795	YCII-related domain
HUT19_RS34615	COG4941	Belongs to the sigma-70 factor family
HUT19_RS34620	COG2186	Transcriptional regulator
HUT19_RS34625	COG1620	l-lactate permease
HUT19_RS34630	COG0247	lactate metabolic process
HUT19_RS34635	COG1139	Iron-sulfur cluster binding protein
HUT19_RS34640	COG1556	Lactate utilization protein
HUT19_RS34670	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HUT19_RS34675	COG1012	belongs to the aldehyde dehydrogenase family
HUT19_RS34695	COG0477	Major facilitator Superfamily
HUT19_RS34700	COG0318	PFAM AMP-dependent synthetase and ligase
HUT19_RS34705	COG1960	acyl-CoA dehydrogenase activity
HUT19_RS34735	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HUT19_RS34740	COG0596	Alpha beta hydrolase
HUT19_RS34775	COG3973	AAA domain
HUT19_RS34790	COG3483	tryptophan 2,3-dioxygenase activity
HUT19_RS34800	COG2151	metal-sulfur cluster biosynthetic enzyme
HUT19_RS34805	COG3396	Phenylacetate-CoA oxygenase
HUT19_RS34815	COG3396	Phenylacetate-CoA oxygenase
HUT19_RS34840	COG3321	synthase
HUT19_RS34840	COG1028	Short-chain dehydrogenase reductase Sdr
HUT19_RS34840	COG0318	PFAM AMP-dependent synthetase and ligase
HUT19_RS34840	COG0300	oxidoreductase activity
HUT19_RS34840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT19_RS34850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT19_RS34855	COG1595	DNA-templated transcription, initiation
HUT19_RS34910	COG0789	Transcriptional regulator
HUT19_RS34945	COG0435	Glutathione S-transferase
HUT19_RS34955	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HUT19_RS34965	COG0395	ABC-type sugar transport system, permease component
HUT19_RS34970	COG1175	transmembrane transport
HUT19_RS34975	COG1653	transport
HUT19_RS34985	COG2186	Transcriptional regulator
HUT19_RS35005	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HUT19_RS35045	COG0596	Alpha beta hydrolase
HUT19_RS35075	COG1819	glycosyl
HUT19_RS35080	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HUT19_RS35090	COG3321	synthase
HUT19_RS35090	COG0604	alcohol dehydrogenase
HUT19_RS35090	COG1028	Short-chain dehydrogenase reductase Sdr
HUT19_RS35115	COG0156	8-amino-7-oxononanoate synthase activity
HUT19_RS35130	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUT19_RS35235	COG1960	acyl-CoA dehydrogenase activity
HUT19_RS35280	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
HUT19_RS35290	COG1131	(ABC) transporter
HUT19_RS35310	COG1349	DNA-binding transcription factor activity
HUT19_RS35315	COG1349	DNA-binding transcription factor activity
HUT19_RS35360	COG4585	Histidine kinase
HUT19_RS35380	COG0277	FAD linked oxidase domain protein
HUT19_RS35400	COG2267	carboxylic ester hydrolase activity
HUT19_RS35415	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUT19_RS35430	COG1233	COG1233 Phytoene dehydrogenase and related
HUT19_RS35435	COG1028	Short-chain dehydrogenase reductase Sdr
HUT19_RS35445	COG1960	acyl-CoA dehydrogenase activity
HUT19_RS35455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HUT19_RS35460	COG1181	Belongs to the D-alanine--D-alanine ligase family
HUT19_RS35480	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HUT19_RS35485	COG3404	Formiminotransferase-cyclodeaminase
HUT19_RS35535	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HUT19_RS35540	COG0646	methionine synthase
HUT19_RS35540	COG1410	methionine synthase
HUT19_RS35545	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HUT19_RS35545	COG0515	serine threonine protein kinase
HUT19_RS35550	COG0515	serine threonine protein kinase
HUT19_RS35550	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HUT19_RS35560	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HUT19_RS35565	COG4106	trans-aconitate 2-methyltransferase activity
HUT19_RS35610	COG4221	oxidoreductase activity
HUT19_RS35660	COG0254	rRNA binding
HUT19_RS35665	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HUT19_RS35675	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HUT19_RS35685	COG0673	inositol 2-dehydrogenase activity
HUT19_RS35690	COG1028	Short-chain dehydrogenase reductase Sdr
HUT19_RS35700	COG2084	Dehydrogenase
HUT19_RS35710	COG1260	myo-inositol-1-phosphate synthase
HUT19_RS35725	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT19_RS35740	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HUT19_RS35770	COG0443	Heat shock 70 kDa protein
HUT19_RS35775	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HUT19_RS35790	COG0542	response to heat
HUT19_RS35805	COG0071	Belongs to the small heat shock protein (HSP20) family
HUT19_RS35830	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HUT19_RS35860	COG3395	kinase activity
HUT19_RS35865	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HUT19_RS35895	COG1280	lysine exporter protein (LysE YggA)
HUT19_RS35925	COG1024	Enoyl-CoA hydratase
HUT19_RS35930	COG1683	Conserved Protein
HUT19_RS35950	COG2345	Transcriptional regulator
HUT19_RS36000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT19_RS36030	COG3552	Protein containing von Willebrand factor type A (VWA) domain
HUT19_RS36035	COG0714	Associated with various cellular activities
HUT19_RS36045	COG0531	amino acid
HUT19_RS36085	COG0667	Aldo Keto reductase
HUT19_RS36090	COG0583	DNA-binding transcription factor activity
HUT19_RS36130	COG1024	Enoyl-CoA hydratase
HUT19_RS36175	COG4106	trans-aconitate 2-methyltransferase activity
HUT19_RS36205	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HUT19_RS36285	COG2205	protein histidine kinase activity
HUT19_RS36290	COG0745	RESPONSE REGULATOR receiver
HUT19_RS36300	COG0366	Alpha amylase catalytic
HUT19_RS36300	COG1470	cell adhesion involved in biofilm formation
HUT19_RS36335	COG2340	Cysteine-rich secretory protein family
HUT19_RS36395	COG1028	Short-chain dehydrogenase reductase Sdr
HUT19_RS36395	COG3321	synthase
HUT19_RS36395	COG0300	oxidoreductase activity
HUT19_RS36395	COG0318	PFAM AMP-dependent synthetase and ligase
HUT19_RS36395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT19_RS36425	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HUT19_RS36445	COG1472	Belongs to the glycosyl hydrolase 3 family
HUT19_RS36450	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUT19_RS36460	COG4585	Histidine kinase
HUT19_RS36465	COG2197	response regulator
HUT19_RS36475	COG1136	(ABC) transporter
HUT19_RS36475	COG0577	efflux transmembrane transporter activity
HUT19_RS36480	COG0577	efflux transmembrane transporter activity
HUT19_RS36480	COG1136	(ABC) transporter
HUT19_RS36500	COG2205	protein histidine kinase activity
HUT19_RS36510	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HUT19_RS36515	COG1404	Belongs to the peptidase S8 family
HUT19_RS36550	COG1742	UPF0060 membrane protein
HUT19_RS36560	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HUT19_RS36565	COG1414	Transcriptional regulator
HUT19_RS36580	COG4948	Mandelate Racemase Muconate Lactonizing
HUT19_RS36585	COG0477	Major facilitator Superfamily
HUT19_RS36605	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HUT19_RS36610	COG0028	Belongs to the TPP enzyme family
HUT19_RS36615	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUT19_RS36625	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUT19_RS36640	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUT19_RS36645	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HUT19_RS36650	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUT19_RS36660	COG1028	Short-chain dehydrogenase reductase Sdr
HUT19_RS36665	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HUT19_RS36720	COG0477	Major facilitator Superfamily
HUT19_RS36730	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HUT19_RS36745	COG0431	NADPH-dependent FMN reductase
HUT19_RS36750	COG4948	Mandelate Racemase Muconate Lactonizing
HUT19_RS36775	COG3387	PFAM Glycoside hydrolase 15-related
HUT19_RS36790	COG0668	transmembrane transport
HUT19_RS36810	COG2124	cytochrome p450
HUT19_RS36815	COG2124	cytochrome p450
HUT19_RS36820	COG2267	carboxylic ester hydrolase activity
HUT19_RS36835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT19_RS36845	COG0019	diaminopimelate decarboxylase activity
HUT19_RS36890	COG0604	alcohol dehydrogenase
HUT19_RS36890	COG3321	synthase
HUT19_RS36890	COG0604	alcohol dehydrogenase
HUT19_RS36890	COG3321	synthase
HUT19_RS36900	COG1136	(ABC) transporter
HUT19_RS36910	COG4585	Histidine kinase
HUT19_RS36930	COG0739	heme binding
HUT19_RS36935	COG2508	Transcriptional regulator
HUT19_RS36945	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUT19_RS36965	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUT19_RS36970	COG0183	Belongs to the thiolase family
HUT19_RS36975	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUT19_RS36975	COG1024	Enoyl-CoA hydratase
HUT19_RS36980	COG2197	response regulator
HUT19_RS36985	COG1960	acyl-CoA dehydrogenase activity
HUT19_RS36990	COG1960	acyl-CoA dehydrogenase activity
HUT19_RS37020	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HUT19_RS37055	COG1063	alcohol dehydrogenase
HUT19_RS37075	COG0326	Molecular chaperone. Has ATPase activity
HUT19_RS37100	COG1309	transcriptional regulator
HUT19_RS37120	COG0697	spore germination
HUT19_RS37125	COG1522	sequence-specific DNA binding
HUT19_RS37165	COG2188	Transcriptional regulator
HUT19_RS37170	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUT19_RS37200	COG0477	Major facilitator Superfamily
HUT19_RS37225	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HUT19_RS37280	COG0583	DNA-binding transcription factor activity
HUT19_RS37285	COG0697	spore germination
HUT19_RS37295	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HUT19_RS37300	COG2080	2 iron, 2 sulfur cluster binding
HUT19_RS37305	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HUT19_RS37310	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HUT19_RS37320	COG2814	Major facilitator Superfamily
HUT19_RS37350	COG3594	Acyltransferase
HUT19_RS37355	COG2376	Dihydroxyacetone kinase
HUT19_RS37360	COG2376	Dihydroxyacetone kinase
HUT19_RS37365	COG4221	oxidoreductase activity
HUT19_RS37370	COG2814	Major facilitator Superfamily
HUT19_RS37375	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HUT19_RS37390	COG1070	Carbohydrate kinase
HUT19_RS37395	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HUT19_RS37400	COG0596	Alpha beta hydrolase
HUT19_RS37415	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HUT19_RS37420	COG0300	oxidoreductase activity
HUT19_RS37430	COG0726	polysaccharide deacetylase
HUT19_RS37435	COG0114	fumarate hydratase activity
HUT19_RS37440	COG2175	clavaminate synthase activity
HUT19_RS37450	COG0583	DNA-binding transcription factor activity
HUT19_RS37465	COG0306	phosphate transporter
HUT19_RS37475	COG1357	PFAM Pentapeptide repeats (8 copies)
HUT19_RS37530	COG0174	glutamine synthetase
HUT19_RS37545	COG4689	acetoacetate decarboxylase
HUT19_RS37575	COG1012	belongs to the aldehyde dehydrogenase family
HUT19_RS37580	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HUT19_RS37585	COG1846	Transcriptional regulator
HUT19_RS37590	COG3511	phospholipase C
HUT19_RS37645	COG0582	viral genome integration into host DNA
HUT19_RS37685	COG2226	methyltransferase
HUT19_RS37805	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUT19_RS37805	COG1522	sequence-specific DNA binding
HUT19_RS37810	COG2313	pseudouridylate synthase activity
HUT19_RS37815	COG0384	phenazine biosynthesis protein PhzF
HUT19_RS37855	COG1396	sequence-specific DNA binding
HUT19_RS37865	COG2815	serine threonine protein kinase
HUT19_RS37865	COG0515	serine threonine protein kinase
HUT19_RS37870	COG1252	NADH dehydrogenase
HUT19_RS37875	COG1595	DNA-templated transcription, initiation
HUT19_RS37885	COG0542	response to heat
HUT19_RS37890	COG1733	regulation of RNA biosynthetic process
HUT19_RS37910	COG2936	dipeptidyl-peptidase activity
HUT19_RS37930	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUT19_RS37990	COG2304	oxidoreductase activity
HUT19_RS37995	COG1131	(ABC) transporter
HUT19_RS38010	COG1215	transferase activity, transferring glycosyl groups
HUT19_RS38030	COG1309	transcriptional regulator
HUT19_RS38035	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HUT19_RS38040	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HUT19_RS38045	COG2080	2 iron, 2 sulfur cluster binding
HUT19_RS38060	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HUT19_RS38075	COG0477	Major facilitator Superfamily
HUT19_RS38090	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HUT19_RS38095	COG3012	SEC-C Motif Domain Protein
HUT19_RS38210	COG2124	cytochrome p450
HUT19_RS38230	COG2340	Cysteine-rich secretory protein family
HUT19_RS38245	COG0531	amino acid
HUT19_RS38255	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HUT19_RS38290	COG1902	pentaerythritol trinitrate reductase activity
HUT19_RS38325	COG1024	Enoyl-CoA hydratase
HUT19_RS38335	COG1028	Short-chain dehydrogenase reductase Sdr
HUT19_RS38365	COG0395	ABC-type sugar transport system, permease component
HUT19_RS38370	COG1175	transmembrane transport
HUT19_RS38385	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
HUT19_RS38390	COG0121	glutamine amidotransferase
HUT19_RS38395	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HUT19_RS38410	COG1960	acyl-CoA dehydrogenase activity
HUT19_RS38415	COG1960	acyl-CoA dehydrogenase activity
HUT19_RS38425	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUT19_RS38430	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUT19_RS38450	COG1940	carbohydrate kinase activity
HUT19_RS38450	COG1846	Transcriptional regulator
HUT19_RS38470	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HUT19_RS38535	COG2018	Roadblock/LC7 domain
HUT19_RS38545	COG1946	Acyl-CoA thioesterase
HUT19_RS38560	COG1132	(ABC) transporter
HUT19_RS38565	COG1132	(ABC) transporter
HUT19_RS38585	COG1132	(ABC) transporter
HUT19_RS38595	COG3458	cephalosporin-C deacetylase activity
HUT19_RS38605	COG0765	amino acid transport
HUT19_RS38610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUT19_RS38635	COG0667	Aldo Keto reductase
HUT19_RS38645	COG3973	AAA domain
HUT19_RS38660	COG2205	protein histidine kinase activity
HUT19_RS38665	COG0667	Aldo Keto reductase
HUT19_RS38680	COG2814	Major facilitator Superfamily
HUT19_RS38705	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
HUT19_RS38705	COG1796	DNA polymerase
HUT19_RS38710	COG2353	YceI-like domain
HUT19_RS38745	COG4585	Histidine kinase
HUT19_RS38760	COG1959	2 iron, 2 sulfur cluster binding
HUT19_RS38790	COG1028	Short-chain dehydrogenase reductase Sdr
HUT19_RS38795	COG1028	Short-chain dehydrogenase reductase Sdr
HUT19_RS38865	COG0596	Alpha beta hydrolase
HUT19_RS38870	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUT19_RS38875	COG3739	integral membrane protein
HUT19_RS38905	COG5504	Zn-dependent protease
HUT19_RS38910	COG2353	YceI-like domain
HUT19_RS38925	COG1063	alcohol dehydrogenase
HUT19_RS38945	COG0506	proline dehydrogenase activity
HUT19_RS39025	COG0697	spore germination
HUT19_RS39030	COG0583	DNA-binding transcription factor activity
HUT19_RS39035	COG4608	Belongs to the ABC transporter superfamily
HUT19_RS39045	COG0601	transmembrane transport
HUT19_RS39060	COG0006	proline dipeptidase activity
HUT19_RS39065	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUT19_RS39085	COG3938	Belongs to the proline racemase family
HUT19_RS39095	COG1802	Transcriptional regulator
HUT19_RS39160	COG1846	Transcriptional regulator
HUT19_RS39180	COG1132	(ABC) transporter
HUT19_RS39260	COG1611	Belongs to the LOG family
HUT19_RS39290	COG2272	Belongs to the type-B carboxylesterase lipase family
HUT19_RS39295	COG0367	asparagine synthase
HUT19_RS39300	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HUT19_RS39320	COG1028	Short-chain dehydrogenase reductase Sdr
HUT19_RS39330	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HUT19_RS39330	COG2146	nitrite reductase [NAD(P)H] activity
HUT19_RS39335	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HUT19_RS39340	COG0243	molybdopterin cofactor binding
HUT19_RS39345	COG2223	nitrite transmembrane transporter activity
HUT19_RS39365	COG2130	NADP-dependent
HUT19_RS39370	COG0475	glutathione-regulated potassium exporter activity
HUT19_RS39400	COG0583	DNA-binding transcription factor activity
HUT19_RS39435	COG2130	NADP-dependent
HUT19_RS39440	COG2130	NADP-dependent
HUT19_RS39460	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HUT19_RS39475	COG0069	glutamate synthase activity
HUT19_RS39560	COG0596	Alpha beta hydrolase
HUT19_RS39600	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT19_RS39605	COG1032	radical SAM domain protein
HUT19_RS39650	COG2271	Major facilitator Superfamily
HUT19_RS39660	COG2197	response regulator
HUT19_RS39665	COG4585	Histidine kinase
HUT19_RS39670	COG2409	Drug exporters of the RND superfamily
HUT19_RS39700	COG3483	tryptophan 2,3-dioxygenase activity
HUT19_RS39705	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUT19_RS39705	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
HUT19_RS39710	COG3290	protein histidine kinase activity
HUT19_RS39715	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HUT19_RS39750	COG0251	oxidation-reduction process
HUT19_RS39755	COG0179	Fumarylacetoacetate (FAA) hydrolase
HUT19_RS39780	COG2146	nitrite reductase [NAD(P)H] activity
HUT19_RS39785	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HUT19_RS39790	COG1126	abc transporter atp-binding protein
HUT19_RS39795	COG0765	amino acid transport
HUT19_RS39800	COG0765	amino acid transport
HUT19_RS39810	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HUT19_RS39815	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HUT19_RS39875	COG3185	4-Hydroxyphenylpyruvate dioxygenase
HUT19_RS39890	COG3629	intracellular signal transduction
HUT19_RS39905	COG0667	Aldo Keto reductase
HUT19_RS39915	COG0367	asparagine synthase
HUT19_RS39920	COG0010	Belongs to the arginase family
HUT19_RS39935	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HUT19_RS39940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT19_RS39950	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HUT19_RS39980	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HUT19_RS39995	COG1454	alcohol dehydrogenase
HUT19_RS39995	COG1012	belongs to the aldehyde dehydrogenase family
HUT19_RS40020	COG0531	amino acid
HUT19_RS40035	COG0549	Belongs to the carbamate kinase family
HUT19_RS40125	COG2366	antibiotic biosynthetic process
HUT19_RS40130	COG0463	Glycosyl transferase, family 2
HUT19_RS40150	COG0438	transferase activity, transferring glycosyl groups
HUT19_RS40175	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT19_RS40200	COG0367	asparagine synthase
HUT19_RS40230	COG2192	nodulation
HUT19_RS40245	COG1132	(ABC) transporter
HUT19_RS40320	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUT19_RS40325	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUT19_RS40380	COG2197	response regulator
HUT19_RS40385	COG4585	Histidine kinase
HUT19_RS40405	COG3835	regulator
HUT19_RS40420	COG3547	Transposase (IS116 IS110 IS902 family)
HUT19_RS40425	COG3547	Transposase (IS116 IS110 IS902 family)
HUT19_RS40460	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HUT19_RS40500	COG1213	nucleotidyl transferase
HUT19_RS40505	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HUT19_RS40510	COG3848	Pyruvate phosphate dikinase
HUT19_RS40510	COG0574	Belongs to the PEP-utilizing enzyme family
HUT19_RS40515	COG2226	methyltransferase
HUT19_RS40550	COG2226	methyltransferase
HUT19_RS40555	COG0477	Major facilitator Superfamily
HUT19_RS40560	COG3634	alkyl hydroperoxide reductase activity
HUT19_RS40575	COG0577	efflux transmembrane transporter activity
HUT19_RS40575	COG1136	(ABC) transporter
HUT19_RS40580	COG0577	efflux transmembrane transporter activity
HUT19_RS40580	COG1136	(ABC) transporter
HUT19_RS40600	COG2801	Transposase and inactivated derivatives
HUT19_RS40605	COG2197	response regulator
HUT19_RS40630	COG2826	transposase and inactivated derivatives, IS30 family
HUT19_RS40650	COG4974	Belongs to the 'phage' integrase family
HUT19_RS41040	COG3883	PFAM NLP P60 protein
HUT19_RS41040	COG0791	NLP P60 protein
HUT19_RS41270	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HUT19_RS41435	COG1192	Involved in chromosome partitioning
HUT19_RS41440	COG1475	DNA binding
HUT19_RS41445	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
HUT19_RS41710	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HUT19_RS41730	COG4195	phage-related replication protein
HUT19_RS42025	COG1674	ftsk spoiiie
HUT19_RS42215	COG1793	dna ligase