locus-tag	class	description
DEH18_RS00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
DEH18_RS00015	ENOG4108J5G	6-phosphogluconate dehydrogenase
DEH18_RS00020	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
DEH18_RS00025	ENOG4105K7N	UPF0232 protein
DEH18_RS00035	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
DEH18_RS00060	ENOG4108UGD	Serine Threonine protein kinase
DEH18_RS00100	ENOG4105ZJT	Cell division protein CrgA
DEH18_RS00110	ENOG4108U4N	(sortase) family
DEH18_RS00125	ENOG4108U4N	(sortase) family
DEH18_RS00130	ENOG4108RN7	integral membrane protein
DEH18_RS00135	ENOG4105CTB	Polyprenyl synthetase
DEH18_RS00145	ENOG4105CJN	penicillin-binding protein
DEH18_RS00150	ENOG4107QHZ	cell cycle protein
DEH18_RS00160	ENOG4105HZM	Fha domain containing protein
DEH18_RS00165	ENOG4105TV9	FHA Domain-Containing protein
DEH18_RS00175	ENOG4107U5X	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
DEH18_RS00180	ENOG4105KVH	Transcriptional regulator
DEH18_RS00195	ENOG4105C1G	acyl-Coa dehydrogenase
DEH18_RS00200	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
DEH18_RS00205	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
DEH18_RS00210	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
DEH18_RS00215	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
DEH18_RS00220	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
DEH18_RS00240	ENOG4108VC7	Protein of unknown function (DUF2587)
DEH18_RS00255	ENOG4107SVH	Potassium channel protein
DEH18_RS00260	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
DEH18_RS00265	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
DEH18_RS00270	ENOG4107QSN	dihydrolipoamide acetyltransferase
DEH18_RS00300	ENOG4107QPV	Serine Threonine protein kinase
DEH18_RS00325	ENOG4105CPP	Dehydrogenase, E1 component
DEH18_RS00330	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
DEH18_RS00365	ENOG4105D29	Helix-turn-helix type 11 domain protein
DEH18_RS00380	ENOG410667J	hydrolase
DEH18_RS00385	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
DEH18_RS00395	ENOG4105DBE	peroxidase
DEH18_RS00400	ENOG4105JDN	Copper resistance protein
DEH18_RS00410	ENOG4108ZX6	Electron transport protein SCO1 SenC
DEH18_RS00435	ENOG4107T6F	Xaa-Pro aminopeptidase
DEH18_RS00455	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
DEH18_RS00470	ENOG4105C0H	protease
DEH18_RS00480	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
DEH18_RS00515	ENOG4105CEY	Amp-dependent synthetase and ligase
DEH18_RS00520	ENOG4108UXN	response regulator
DEH18_RS00560	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
DEH18_RS00580	ENOG4108N6D	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
DEH18_RS00625	ENOG4105C79	DNA protecting protein DprA
DEH18_RS00630	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
DEH18_RS00635	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
DEH18_RS00665	ENOG4105CNU	cell division protein FtsK
DEH18_RS00690	ENOG4106CY5	excisionase
DEH18_RS00695	ENOG4107T65	Integrase
DEH18_RS00700	ENOG4105BZU	Histidine kinase
DEH18_RS00715	ENOG4108Z6B	deaminase
DEH18_RS00730	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
DEH18_RS00745	ENOG4105IIU	Aminopeptidase
DEH18_RS00755	ENOG4107S91	Sodium hydrogen exchanger
DEH18_RS00780	ENOG4108R85	Short chain dehydrogenase
DEH18_RS00785	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
DEH18_RS00800	ENOG4108XEP	Alpha Beta Hydrolase Fold protein
DEH18_RS00805	ENOG4105ECP	epimerase
DEH18_RS00815	ENOG4105DU6	RNA polymerase
DEH18_RS00845	ENOG4106NZI	LysR family Transcriptional regulator
DEH18_RS00850	ENOG4105C2C	drug resistance transporter, Bcr CflA
DEH18_RS00890	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
DEH18_RS00895	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
DEH18_RS00905	ENOG4108ZHR	arsR family transcriptional regulator
DEH18_RS00910	ENOG4105MUA	Resistance protein
DEH18_RS00915	ENOG4105CFH	Aspartokinase
DEH18_RS00940	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
DEH18_RS00955	ENOG4105EE8	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
DEH18_RS00970	ENOG41081F0	Precorrin-8x methylmutase
DEH18_RS00980	ENOG4105CTK	cobaltochelatase, cobn subunit
DEH18_RS01010	ENOG4105BZ4	penicillin-binding protein
DEH18_RS01035	ENOG4105KME	endoribonuclease L-psp
DEH18_RS01045	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
DEH18_RS01060	ENOG4105P8F	nudix hydrolase
DEH18_RS01075	ENOG4105D74	hydrolase
DEH18_RS01090	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
DEH18_RS01095	ENOG4107B2H	carbonic anhydrase
DEH18_RS01155	ENOG4108I5C	dEAD DEAH box helicase
DEH18_RS01160	ENOG4105WN5	stage II sporulation protein
DEH18_RS01165	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
DEH18_RS01170	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
DEH18_RS01185	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
DEH18_RS01190	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
DEH18_RS01225	ENOG4108SQ4	Glyoxalase Bleomycin resistance protein (Dioxygenase
DEH18_RS01250	ENOG4105EBM	Alpha Beta Hydrolase Fold protein
DEH18_RS01255	ENOG4105D17	glycoside hydrolase, family 3 domain protein
DEH18_RS01265	ENOG4107R3A	FAD linked oxidase domain protein
DEH18_RS01280	ENOG4105PGM	cation diffusion facilitator family transporter
DEH18_RS01290	ENOG41082VC	UPF0145 protein
DEH18_RS01300	ENOG4105C57	major facilitator superfamily
DEH18_RS01325	ENOG4106T9R	serine protease
DEH18_RS01335	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
DEH18_RS01360	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
DEH18_RS01400	ENOG4107RPC	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
DEH18_RS01405	ENOG4105BZU	Histidine kinase
DEH18_RS01410	ENOG4105WH1	Two component transcriptional regulator luxr family
DEH18_RS01425	ENOG4105BZU	Histidine kinase
DEH18_RS01430	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
DEH18_RS01445	ENOG4108VJ1	Transcriptional regulator (CarD family
DEH18_RS01450	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
DEH18_RS01455	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
DEH18_RS01465	ENOG4105DEF	Extracellular solute-binding protein, family 5
DEH18_RS01480	ENOG410905P	Pyridoxamine 5-phosphate
DEH18_RS01485	ENOG4105C8N	cysteinyl-tRNA synthetase
DEH18_RS01490	ENOG4105C2N	RNA methyltransferase TrmH family group 3
DEH18_RS01510	ENOG4108IJ9	(ABC) transporter
DEH18_RS01550	ENOG4105EX0	alpha-galactosidase
DEH18_RS01565	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
DEH18_RS01575	ENOG4105BZU	Histidine kinase
DEH18_RS01590	ENOG4105CE4	GlcNAc 6-P deacetylase
DEH18_RS01610	ENOG4108JGH	Tetr family transcriptional regulator
DEH18_RS01615	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
DEH18_RS01625	ENOG4105C3Q	Glycosyl transferase, family 2
DEH18_RS01640	ENOG4105VEQ	Cold shock protein
DEH18_RS01655	ENOG4105R1U	AraC Family Transcriptional Regulator
DEH18_RS01660	ENOG4105EU0	Major facilitator Superfamily
DEH18_RS01710	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
DEH18_RS01720	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DEH18_RS01725	ENOG4106G6Q	Transcriptional regulator
DEH18_RS01775	ENOG4105F27	Major Facilitator
DEH18_RS01785	ENOG4106N3A	copper homeostasis protein cutc
DEH18_RS01795	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
DEH18_RS01835	ENOG4105CEY	Amp-dependent synthetase and ligase
DEH18_RS01840	ENOG4105CFI	type iii restriction protein res subunit
DEH18_RS01855	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
DEH18_RS01860	ENOG4108KXM	LysR family Transcriptional regulator
DEH18_RS01870	ENOG4105GYP	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity)
DEH18_RS01875	ENOG4107SI7	Substrate-binding region of abc-type glycine betaine transport system
DEH18_RS01880	ENOG4108IJ8	ABC transporter
DEH18_RS01885	ENOG4105E90	ABC transporter
DEH18_RS01890	ENOG4105E90	ABC transporter
DEH18_RS01905	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
DEH18_RS01910	ENOG4108MES	Periplasmic binding protein
DEH18_RS01915	ENOG4105E0A	ABC, transporter
DEH18_RS01920	ENOG4105TVJ	transport system, permease
DEH18_RS01925	ENOG4105DQ5	transport system permease protein
DEH18_RS01940	ENOG4105VEQ	Cold shock protein
DEH18_RS01950	ENOG4105ECR	NmrA family
DEH18_RS01955	ENOG4105E63	Pfam:DUF178
DEH18_RS01960	ENOG4108UIH	futalosine nucleosidase
DEH18_RS01985	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
DEH18_RS01995	ENOG4105C7N	Xanthine uracil vitamin C permease
DEH18_RS02005	ENOG4107MII	Sugar-specific transcriptional regulator TrmB
DEH18_RS02025	ENOG4105CPC	Aldo Keto reductase
DEH18_RS02065	ENOG4107R8H	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
DEH18_RS02075	ENOG4105CQB	FAD linked oxidase domain protein
DEH18_RS02090	ENOG4108CIP	transcriptional regulator
DEH18_RS02105	ENOG4107QX3	carboxylase
DEH18_RS02120	ENOG4105CGU	Enoyl-CoA hydratase
DEH18_RS02140	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
DEH18_RS02145	ENOG4105BZU	Histidine kinase
DEH18_RS02150	ENOG4108SU4	UPF0309 protein
DEH18_RS02200	ENOG41082AN	stage II sporulation protein
DEH18_RS02205	ENOG4105CEY	Amp-dependent synthetase and ligase
DEH18_RS02215	ENOG4105CC9	acyl-Coa dehydrogenase
DEH18_RS02220	ENOG4105D2B	acyl-CoA dehydrogenase
DEH18_RS02235	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
DEH18_RS02240	ENOG4105C26	Dehydrogenase
DEH18_RS02245	ENOG4107QPD	alcohol dehydrogenase
DEH18_RS02250	ENOG4105ECQ	AraC Family Transcriptional Regulator
DEH18_RS02265	ENOG4105MXW	flavin reductase domain protein, FMN-binding
DEH18_RS02270	ENOG4105CGU	Enoyl-CoA hydratase
DEH18_RS02280	ENOG4105H3G	oxidoreductase
DEH18_RS02310	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
DEH18_RS02315	ENOG4108762	serine threonine protein kinase
DEH18_RS02330	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
DEH18_RS02345	ENOG4105CEY	Amp-dependent synthetase and ligase
DEH18_RS02360	ENOG4105F0K	SARP family transcriptional regulator
DEH18_RS02375	ENOG4105CHR	reductase
DEH18_RS02390	ENOG4105CPC	Aldo Keto reductase
DEH18_RS02410	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
DEH18_RS02415	ENOG41065RQ	ADP-ribosylation crystallin J1
DEH18_RS02435	ENOG4105DZ1	carboxypeptidase
DEH18_RS02495	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
DEH18_RS02500	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
DEH18_RS02510	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
DEH18_RS02515	ENOG4108MXC	l-carnitine dehydratase bile acid-inducible protein F
DEH18_RS02535	ENOG4105FDP	GntR family transcriptional regulator
DEH18_RS02585	ENOG4105VTR	Integrase
DEH18_RS02595	ENOG4105BZU	Histidine kinase
DEH18_RS02600	ENOG4107T5V	SNARE associated Golgi
DEH18_RS02605	ENOG4105D17	glycoside hydrolase, family 3 domain protein
DEH18_RS02610	ENOG4105CS1	NAD(P)H quinone oxidoreductase
DEH18_RS02630	ENOG4105E98	transcriptional regulator DeoR family
DEH18_RS02635	ENOG4105DE4	1-phosphofructokinase
DEH18_RS02640	ENOG4105DM4	PTS System
DEH18_RS02655	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
DEH18_RS02665	ENOG4107USC	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
DEH18_RS02690	ENOG41080UU	5-formyltetrahydrofolate cyclo-ligase
DEH18_RS02695	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
DEH18_RS02705	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
DEH18_RS02710	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
DEH18_RS02715	ENOG4108Z9I	-acetyltransferase
DEH18_RS02750	ENOG4105DND	Transcriptional regulator
DEH18_RS02765	ENOG4105KPY	Small multidrug resistance protein
DEH18_RS02770	ENOG4107SQU	synthase
DEH18_RS02775	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
DEH18_RS02785	ENOG4105CGK	Exodeoxyribonuclease III
DEH18_RS02795	ENOG4105F95	Monooxygenase
DEH18_RS02800	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
DEH18_RS02805	ENOG4108R85	Short chain dehydrogenase
DEH18_RS02820	ENOG4105EYF	MMPL domain protein
DEH18_RS02825	ENOG4105KF0	sporulation and cell division protein, SsgA
DEH18_RS02850	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
DEH18_RS02855	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
DEH18_RS02865	ENOG4105F8V	Hydrolase, tatD family
DEH18_RS02890	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
DEH18_RS02900	ENOG4105C5H	ABC transporter
DEH18_RS02945	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
DEH18_RS02950	ENOG4105WH1	Two component transcriptional regulator luxr family
DEH18_RS02970	ENOG4105WH1	Two component transcriptional regulator luxr family
DEH18_RS02980	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
DEH18_RS02985	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
DEH18_RS03000	ENOG4105VEQ	Cold shock protein
DEH18_RS03005	ENOG4105C1J	atp-dependent rna helicase
DEH18_RS03020	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
DEH18_RS03050	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
DEH18_RS03055	ENOG4107XT7	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
DEH18_RS03060	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
DEH18_RS03065	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
DEH18_RS03080	ENOG4105BZU	Histidine kinase
DEH18_RS03105	ENOG4108KGH	TRANSCRIPTIONal
DEH18_RS03145	ENOG4105EBR	Carboxylesterase
DEH18_RS03150	ENOG4105CY0	Metallo-Beta-Lactamase
DEH18_RS03165	ENOG4105KV4	Transcriptional regulator
DEH18_RS03220	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
DEH18_RS03260	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
DEH18_RS03265	ENOG4107RBB	ABC transporter, permease
DEH18_RS03270	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
DEH18_RS03305	ENOG4106PGW	Short-chain dehydrogenase reductase Sdr
DEH18_RS03315	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
DEH18_RS03330	ENOG4108VGI	doxx family
DEH18_RS03355	ENOG4105CHU	acetyl-coa acetyltransferase
DEH18_RS03375	ENOG41061AU	MarR family Transcriptional regulator
DEH18_RS03390	ENOG4108EQM	faD-dependent pyridine nucleotide-disulfide oxidoreductase
DEH18_RS03410	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
DEH18_RS03415	ENOG4107YY3	extracellular solute-binding protein family 1
DEH18_RS03440	ENOG4108TKH	Nitroreductase
DEH18_RS03450	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
DEH18_RS03485	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
DEH18_RS03490	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
DEH18_RS03495	ENOG4105CGP	Urocanate hydratase
DEH18_RS03510	ENOG4105CI2	imidazolone-5-propionate hydrolase
DEH18_RS03535	ENOG4105C57	major facilitator superfamily
DEH18_RS03540	ENOG4108N6D	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
DEH18_RS03580	ENOG4105DUX	Transporter
DEH18_RS03585	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
DEH18_RS03590	ENOG4105BZU	Histidine kinase
DEH18_RS03650	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
DEH18_RS03660	ENOG4108KGH	TRANSCRIPTIONal
DEH18_RS03665	ENOG4108S4H	thioesterase Superfamily protein
DEH18_RS03685	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
DEH18_RS03705	ENOG4108KGH	TRANSCRIPTIONal
DEH18_RS03725	ENOG41064MX	Tetr family transcriptional regulator
DEH18_RS03750	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
DEH18_RS03760	ENOG41088YA	Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives (By similarity)
DEH18_RS03765	ENOG4105EIH	LPPG Fo 2-phospho-L-lactate transferase
DEH18_RS03775	ENOG4105K51	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
DEH18_RS03780	ENOG4107RGC	Glycosyl transferase, family 2
DEH18_RS03800	ENOG4107QKV	phosphomannomutase
DEH18_RS03805	ENOG4105W49	UPF0434 protein
DEH18_RS03815	ENOG4105EIP	mannose-6-phosphate isomerase
DEH18_RS03825	ENOG4105DM4	PTS System
DEH18_RS03830	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
DEH18_RS03870	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
DEH18_RS03875	ENOG4108WQ6	secreted protein
DEH18_RS03890	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
DEH18_RS03895	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
DEH18_RS03900	ENOG4105BZU	Histidine kinase
DEH18_RS03905	ENOG4105G3P	Lipoprotein lpqB
DEH18_RS03915	ENOG4108S7Q	sigma 54 modulation protein ribosomal protein S30ea
DEH18_RS03920	ENOG4105WH1	Two component transcriptional regulator luxr family
DEH18_RS03930	ENOG4108YYQ	gCN5-related N-acetyltransferase
DEH18_RS03935	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
DEH18_RS03960	ENOG4105C7I	Dehydrogenase
DEH18_RS03970	ENOG4108I69	Glycosyl transferases group 1
DEH18_RS03985	ENOG4107ISF	Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component the mycobacterial cell wall. Catalyzes the transfer of arabinofuranosyl (Araf) residues residue from the sugar donor beta-D-arabinofuranosyl-1-monophosphoryldecaprenol (DPA) to the arabinan domain to form terminal beta-(1- 2)-linked Araf residues, which marks the end point for AG arabinan biosynthesis before decoration with mycolic acids
DEH18_RS03990	ENOG4105J5G	Transferase hexapeptide repeat containing protein
DEH18_RS04000	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
DEH18_RS04035	ENOG4107SJB	teichoic acid biosynthesis
DEH18_RS04055	ENOG4106YN8	Prenyltransferase
DEH18_RS04065	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
DEH18_RS04090	ENOG4108UGD	Serine Threonine protein kinase
DEH18_RS04095	ENOG4108QVN	serine threonine protein kinase
DEH18_RS04100	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
DEH18_RS04115	ENOG4105CAK	Cell division ATP-binding protein ftsE
DEH18_RS04120	ENOG4107RYD	Part of the ABC transporter FtsEX involved in cellular division (By similarity)
DEH18_RS04125	ENOG4105CN1	protease
DEH18_RS04130	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
DEH18_RS04150	ENOG4106NZI	LysR family Transcriptional regulator
DEH18_RS04165	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
DEH18_RS04170	ENOG4108IND	Tetr family transcriptional regulator
DEH18_RS04190	ENOG4105EEM	helicase
DEH18_RS04200	ENOG4105VEQ	Cold shock protein
DEH18_RS04210	ENOG4108426	dNA-binding protein
DEH18_RS04220	ENOG4108TZY	GntR Family Transcriptional Regulator
DEH18_RS04230	ENOG4106SMU	thiamine transporter membrane protein
DEH18_RS04235	ENOG4108I5D	sulfate abc transporter
DEH18_RS04240	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
DEH18_RS04245	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
DEH18_RS04250	ENOG4108UJU	UPF0301 protein
DEH18_RS04310	ENOG4108ME1	Peptidase M55 D-aminopeptidase
DEH18_RS04320	ENOG4105XN3	extracellular solute-binding protein family 1
DEH18_RS04330	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
DEH18_RS04335	ENOG4105E2D	ec 3.2.1.52
DEH18_RS04350	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
DEH18_RS04380	ENOG4105CNA	YD repeat protein
DEH18_RS04400	ENOG4108KSA	LysR family transcriptional regulator
DEH18_RS04410	ENOG4107ZR7	Membrane
DEH18_RS04435	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
DEH18_RS04440	ENOG4105CQB	FAD linked oxidase domain protein
DEH18_RS04450	ENOG4105KF0	sporulation and cell division protein, SsgA
DEH18_RS04475	ENOG4108RWI	nicotinamidase
DEH18_RS04485	ENOG4105KEN	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
DEH18_RS04495	ENOG4105C85	amino acid
DEH18_RS04525	ENOG4108RQ5	Beta-lactamase domain-containing protein
DEH18_RS04540	ENOG4105CI1	PTS System
DEH18_RS04545	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
DEH18_RS04555	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
DEH18_RS04565	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
DEH18_RS04585	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
DEH18_RS04590	ENOG4108URH	decarboxylase
DEH18_RS04610	ENOG4105CSH	Transporter
DEH18_RS04625	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
DEH18_RS04630	ENOG4105KPY	Small multidrug resistance protein
DEH18_RS04635	ENOG4105BZ4	penicillin-binding protein
DEH18_RS04650	ENOG4105CJ1	ABC, transporter
DEH18_RS04660	ENOG4106BRA	Membrane
DEH18_RS04675	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
DEH18_RS04680	ENOG4105ERH	Fumarylacetoacetate hydrolase
DEH18_RS04685	ENOG4105D9R	oxidoreductase
DEH18_RS04690	ENOG41080U6	GntR family transcriptional regulator
DEH18_RS04695	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
DEH18_RS04715	ENOG4108N53	binding-protein-dependent transport systems inner membrane Component
DEH18_RS04730	ENOG4108W9Q	Endoglucanase (EC 3.2.1.4)
DEH18_RS04735	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
DEH18_RS04760	ENOG4108M1A	Chitin-binding protein
DEH18_RS04805	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
DEH18_RS04810	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
DEH18_RS04820	ENOG4105RE0	Asp Glu hydantoin racemase
DEH18_RS04825	ENOG4105DEN	Luciferase family
DEH18_RS04830	ENOG4105BZU	Histidine kinase
DEH18_RS04890	ENOG4108RQS	Two component transcriptional regulator (Winged helix family
DEH18_RS04895	ENOG410804D	Sensor Signal Transduction Histidine Kinase
DEH18_RS04900	ENOG4108NNZ	chitinase
DEH18_RS04905	ENOG4105ETE	Transcriptional regulator (LacI family
DEH18_RS04910	ENOG4105DR5	peptidase
DEH18_RS04920	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
DEH18_RS04925	ENOG4105ECQ	AraC Family Transcriptional Regulator
DEH18_RS04940	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
DEH18_RS04950	ENOG4105E2D	ec 3.2.1.52
DEH18_RS04960	ENOG4105C1G	acyl-Coa dehydrogenase
DEH18_RS04965	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
DEH18_RS04975	ENOG4107QX3	carboxylase
DEH18_RS04985	ENOG4105C1G	acyl-Coa dehydrogenase
DEH18_RS04990	ENOG4105C29	acyl-CoA thioesterase
DEH18_RS04995	ENOG4108XFF	
DEH18_RS05020	ENOG4105ETE	Transcriptional regulator (LacI family
DEH18_RS05045	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
DEH18_RS05050	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
DEH18_RS05055	ENOG4105CNN	ABC, transporter
DEH18_RS05060	ENOG4105C2J	ABC transporter
DEH18_RS05065	ENOG4105ETE	Transcriptional regulator (LacI family
DEH18_RS05070	ENOG4105C7H	Helicase, RecD TraA family
DEH18_RS05095	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
DEH18_RS05115	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
DEH18_RS05130	ENOG4107ZQV	short-chain dehydrogenase reductase
DEH18_RS05235	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
DEH18_RS05290	ENOG4105WH1	Two component transcriptional regulator luxr family
DEH18_RS05295	ENOG4108S01	response regulator
DEH18_RS05300	ENOG4108ZGX	Histidine kinase
DEH18_RS05330	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
DEH18_RS05350	ENOG4105C19	ABC transporter
DEH18_RS05370	ENOG4105VMP	Transcriptional regulator
DEH18_RS05445	ENOG410842T	Pterin carbinolamine dehydratase
DEH18_RS05450	ENOG4105C2J	ABC transporter
DEH18_RS05465	ENOG4105CRQ	synthase (Component I)
DEH18_RS05470	ENOG4105DDQ	anthranilate synthase
DEH18_RS05475	ENOG4108I0Q	anthranilate phosphoribosyltransferase
DEH18_RS05480	ENOG4105DK0	Indole-3-glycerol phosphate synthase
DEH18_RS05485	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
DEH18_RS05500	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
DEH18_RS05505	ENOG4105MCD	Part of cytochrome c oxidase, its function is
DEH18_RS05510	ENOG4105BZ9	Cytochrome C oxidase, subunit I
DEH18_RS05515	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
DEH18_RS05520	ENOG4105CEY	Amp-dependent synthetase and ligase
DEH18_RS05530	ENOG4105JZI	cytochrome P450
DEH18_RS05550	ENOG41065SU	Two-component system sensor kinase
DEH18_RS05555	ENOG4108KXV	response regulator
DEH18_RS05565	ENOG4105EXC	Acyl-transferase
DEH18_RS05575	ENOG4105DTD	Dehydrogenase
DEH18_RS05595	ENOG4105CHR	reductase
DEH18_RS05605	ENOG4105CEY	Amp-dependent synthetase and ligase
DEH18_RS05630	ENOG4105VHU	single-stranded DNA-binding protein
DEH18_RS05655	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
DEH18_RS05670	ENOG4108Z18	K06886 hemoglobin
DEH18_RS05675	ENOG4105CMI	transporter
DEH18_RS05680	ENOG4105CJ1	ABC, transporter
DEH18_RS05695	ENOG4105CT1	(ABC) transporter
DEH18_RS05730	ENOG4105II7	pyrroline-5-carboxylate reductase
DEH18_RS05735	ENOG4105D8X	mechanosensitive ion channel
DEH18_RS05745	ENOG4105CPE	K01197 hyaluronoglucosaminidase EC 3.2.1.35
DEH18_RS05790	ENOG4108KXM	LysR family Transcriptional regulator
DEH18_RS05800	ENOG4105MC2	DSBA oxidoreductase
DEH18_RS05805	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
DEH18_RS05810	ENOG4105C85	amino acid
DEH18_RS05820	ENOG4105C85	amino acid
DEH18_RS05865	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
DEH18_RS05875	ENOG4105CJW	magnesium transporter
DEH18_RS05880	ENOG4108TGC	Acyltransferase
DEH18_RS05900	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
DEH18_RS05905	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
DEH18_RS05910	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
DEH18_RS05915	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
DEH18_RS05935	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
DEH18_RS05955	ENOG4108IJG	ABC transporter substrate-binding protein
DEH18_RS05960	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
DEH18_RS05970	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
DEH18_RS05975	ENOG4105DFF	Rod shape-determining protein mreb
DEH18_RS05990	ENOG4105CJN	penicillin-binding protein
DEH18_RS05995	ENOG4105CNI	cell division protein FtsW
DEH18_RS06025	ENOG4105C03	ribonuclease
DEH18_RS06030	ENOG410826X	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
DEH18_RS06035	ENOG4105K46	50S ribosomal protein l27
DEH18_RS06040	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DEH18_RS06085	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
DEH18_RS06095	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
DEH18_RS06110	ENOG4105D0M	Protease HtpX homolog
DEH18_RS06120	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
DEH18_RS06155	ENOG4108VJY	integral membrane protein
DEH18_RS06165	ENOG4105C8T	Leucyl-tRNA synthetase
DEH18_RS06175	ENOG4105EPR	degv family
DEH18_RS06190	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
DEH18_RS06195	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
DEH18_RS06220	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
DEH18_RS06225	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
DEH18_RS06230	ENOG4107QWG	2-Nitropropane dioxygenase
DEH18_RS06240	ENOG4107YU2	histidine triad (hIT) protein
DEH18_RS06245	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
DEH18_RS06260	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
DEH18_RS06275	ENOG4105MSB	protein, conserved in bacteria
DEH18_RS06285	ENOG4107VNR	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
DEH18_RS06295	ENOG4105D7K	pfkb domain protein
DEH18_RS06300	ENOG4105F8D	glycoside hydrolase family 4
DEH18_RS06305	ENOG4105EQX	glucarate dehydratase
DEH18_RS06315	ENOG4107QXN	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
DEH18_RS06330	ENOG4105CS2	ec 3.2.1.21
DEH18_RS06340	ENOG4108RCM	Nitroreductase
DEH18_RS06345	ENOG4106DBE	Involved in DNA repair and RecF pathway recombination (By similarity)
DEH18_RS06350	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
DEH18_RS06365	ENOG4105EJ2	Transcriptional regulator
DEH18_RS06395	ENOG4105FDK	ABC transporter
DEH18_RS06405	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
DEH18_RS06410	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
DEH18_RS06415	ENOG4108A65	Transcriptional regulator
DEH18_RS06420	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
DEH18_RS06425	ENOG4105VUN	Transcriptional regulator
DEH18_RS06485	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
DEH18_RS06495	ENOG4108MRH	transcriptional regulatory protein
DEH18_RS06505	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
DEH18_RS06515	ENOG4105CEY	Amp-dependent synthetase and ligase
DEH18_RS06520	ENOG4107RSM	transcriptional regulator
DEH18_RS06545	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
DEH18_RS06555	ENOG4105C7K	acetolactate synthase
DEH18_RS06560	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
DEH18_RS06565	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
DEH18_RS06570	ENOG4105NDH	peptidase s1 and s6 chymotrypsin hap
DEH18_RS06590	ENOG4105C87	Aminotransferase class I and II
DEH18_RS06640	ENOG4105DQE	DNA ligase
DEH18_RS06645	ENOG4105FDF	Could be involved in DNA repair (By similarity)
DEH18_RS06665	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
DEH18_RS06675	ENOG41073B4	coagulation factor 5 8 type domain-containing protein
DEH18_RS06680	ENOG4108M6P	methyltransferase
DEH18_RS06705	ENOG41090MY	MarR family Transcriptional regulator
DEH18_RS06710	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
DEH18_RS06715	ENOG4108ZHJ	Organic hydroperoxide resistance protein
DEH18_RS06735	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
DEH18_RS06745	ENOG41082KT	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
DEH18_RS06750	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
DEH18_RS06775	ENOG4105VUF	Transcriptional regulator
DEH18_RS06790	ENOG4105WH1	Two component transcriptional regulator luxr family
DEH18_RS06825	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
DEH18_RS06870	ENOG4105DAX	Pfam:DUF2983
DEH18_RS06935	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
DEH18_RS06960	ENOG4106A3M	Cytochrome p-450
DEH18_RS06965	ENOG4105F2C	Acetyl-CoA acetyltransferase
DEH18_RS06970	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
DEH18_RS06975	ENOG4107T5V	SNARE associated Golgi
DEH18_RS06995	ENOG4105BZ1	(ABC) transporter
DEH18_RS07010	ENOG4105EWU	Squalene--hopene cyclase
DEH18_RS07035	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
DEH18_RS07055	ENOG4105E7W	lamb ycsf family protein
DEH18_RS07060	ENOG4105P4J	Allophanate hydrolase, subunit 1
DEH18_RS07065	ENOG4107R7A	Allophanate hydrolase subunit 2
DEH18_RS07070	ENOG4108SGK	Tetr family transcriptional regulator
DEH18_RS07075	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
DEH18_RS07080	ENOG4107QVI	Methyltransferase, type 11
DEH18_RS07090	ENOG4105DYW	oxidoreductase
DEH18_RS07100	ENOG4108RU2	n-acetylmuramoyl-l-alanine amidase
DEH18_RS07120	ENOG4105BZU	Histidine kinase
DEH18_RS07135	ENOG4105CHR	reductase
DEH18_RS07150	ENOG4105EGD	dinuclear metal center protein, YbgI family
DEH18_RS07160	ENOG4105CVJ	phosphoglycerate mutase
DEH18_RS07165	ENOG4108UHU	Aldolase
DEH18_RS07170	ENOG4107XFJ	UPF0246 protein
DEH18_RS07175	ENOG4105DNP	FAD linked oxidase domain protein
DEH18_RS07215	ENOG4105BZU	Histidine kinase
DEH18_RS07250	ENOG4105CJ1	ABC, transporter
DEH18_RS07265	ENOG4105CJ1	ABC, transporter
DEH18_RS07280	ENOG4105D9P	serine threonine protein kinase
DEH18_RS07330	ENOG4108Z6Z	Transcriptional regulator
DEH18_RS07340	ENOG4105DMF	Dehydrogenase
DEH18_RS07350	ENOG4105EMU	Dehydrogenase
DEH18_RS07355	ENOG4105C2C	drug resistance transporter, Bcr CflA
DEH18_RS07360	ENOG4107S1E	Beta-lactamase
DEH18_RS07370	ENOG4105CIK	Amidinotransferase
DEH18_RS07390	ENOG4106A0S	
DEH18_RS07395	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
DEH18_RS07400	ENOG4105CJ1	ABC, transporter
DEH18_RS07410	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
DEH18_RS07420	ENOG4107TXC	Transcriptional regulator
DEH18_RS07430	ENOG4105E0Y	RtcB Protein
DEH18_RS07460	ENOG4105I1K	ABC transporter
DEH18_RS07505	ENOG4108IND	Tetr family transcriptional regulator
DEH18_RS07525	ENOG4107XZ0	Peptidase M50
DEH18_RS07555	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
DEH18_RS07560	ENOG4105C57	major facilitator superfamily
DEH18_RS07575	ENOG4105F27	Major Facilitator
DEH18_RS07585	ENOG4105C4K	Nad synthetase
DEH18_RS07590	ENOG4107R16	Multicopper oxidase
DEH18_RS07605	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
DEH18_RS07645	ENOG4108UZX	fmn reductase
DEH18_RS07655	ENOG4105C5F	glutamine synthetase
DEH18_RS07660	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
DEH18_RS07670	ENOG4105ETE	Transcriptional regulator (LacI family
DEH18_RS07675	ENOG4105CG3	alpha amylase, catalytic region
DEH18_RS07685	ENOG4105D56	permease protein
DEH18_RS07695	ENOG4105CG3	alpha amylase, catalytic region
DEH18_RS07705	ENOG4108XZR	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity (By similarity)
DEH18_RS07715	ENOG4105WH1	Two component transcriptional regulator luxr family
DEH18_RS07720	ENOG41060BG	Tetr family transcriptional regulator
DEH18_RS07740	ENOG4105WH1	Two component transcriptional regulator luxr family
DEH18_RS07750	ENOG4105NDH	peptidase s1 and s6 chymotrypsin hap
DEH18_RS07765	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
DEH18_RS07780	ENOG4108222	arsenate reductase
DEH18_RS07790	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
DEH18_RS07795	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
DEH18_RS07810	ENOG4105D4P	Coproporphyrinogen iii oxidase
DEH18_RS07900	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
DEH18_RS07905	ENOG4105E9K	Isocitrate dehydrogenase
DEH18_RS07940	ENOG4105WH1	Two component transcriptional regulator luxr family
DEH18_RS07945	ENOG4105BZU	Histidine kinase
DEH18_RS07950	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
DEH18_RS07965	ENOG4105D56	permease protein
DEH18_RS07975	ENOG4105E2R	ROK family
DEH18_RS08050	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
DEH18_RS08055	ENOG4105EHG	Permease protein
DEH18_RS08065	ENOG4105E0A	ABC, transporter
DEH18_RS08070	ENOG4105EHG	Permease protein
DEH18_RS08100	ENOG4105CHR	reductase
DEH18_RS08105	ENOG4105D29	Helix-turn-helix type 11 domain protein
DEH18_RS08110	ENOG4105C8J	)-transporter
DEH18_RS08120	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
DEH18_RS08140	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
DEH18_RS08145	ENOG41080Z7	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
DEH18_RS08150	ENOG4105CRK	lysyL-tRNA synthetase
DEH18_RS08155	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
DEH18_RS08205	ENOG4105WH1	Two component transcriptional regulator luxr family
DEH18_RS08220	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
DEH18_RS08240	ENOG4105C3J	Cysteine desulfurase
DEH18_RS08245	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
DEH18_RS08250	ENOG4105BZ9	Cytochrome C oxidase, subunit I
DEH18_RS08255	ENOG4105MCD	Part of cytochrome c oxidase, its function is
DEH18_RS08270	ENOG4105CCU	oxidase (Subunit III)
DEH18_RS08275	ENOG4107UDY	cytochrome C
DEH18_RS08280	ENOG4107EUI	c reductase, iron-sulfur
DEH18_RS08285	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
DEH18_RS08290	ENOG4108I0Q	anthranilate phosphoribosyltransferase
DEH18_RS08330	ENOG4105C87	Aminotransferase class I and II
DEH18_RS08335	ENOG4105DFD	Na H antiporter
DEH18_RS08355	ENOG4105BZW	Glycerate kinase
DEH18_RS08365	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
DEH18_RS08445	ENOG4105D0U	Arsenite-activated ATPase (ArsA)
DEH18_RS08455	ENOG4105DKQ	ROK family
DEH18_RS08465	ENOG4108VHC	Short-chain dehydrogenase reductase Sdr
DEH18_RS08495	ENOG4105WH1	Two component transcriptional regulator luxr family
DEH18_RS08500	ENOG4105CTQ	phosphohexokinase
DEH18_RS08505	ENOG4105C5I	Dehydrogenase
DEH18_RS08515	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
DEH18_RS08525	ENOG4108UQY	Iron-storage protein
DEH18_RS08535	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
DEH18_RS08555	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
DEH18_RS08580	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
DEH18_RS08595	ENOG4107VFM	Dehydrogenase
DEH18_RS08600	ENOG4108IG5	Transcriptional regulator
DEH18_RS08610	ENOG4107T0D	ABC, transporter
DEH18_RS08620	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
DEH18_RS08650	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
DEH18_RS08660	ENOG4105CJN	penicillin-binding protein
DEH18_RS08665	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
DEH18_RS08675	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
DEH18_RS08680	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
DEH18_RS08690	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
DEH18_RS08700	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
DEH18_RS08705	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
DEH18_RS08710	ENOG4105DFA	alanine racemase domain protein
DEH18_RS08715	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
DEH18_RS08725	ENOG4107VQS	DivIVA family
DEH18_RS08735	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
DEH18_RS08740	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DEH18_RS08745	ENOG4107ZIW	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
DEH18_RS08795	ENOG4105C0B	DNA polymerase III (alpha subunit)
DEH18_RS08820	ENOG4108Z66	YbaK ebsC protein
DEH18_RS08835	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
DEH18_RS08840	ENOG4105CIH	Imidazole acetol-phosphate transaminase
DEH18_RS08845	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
DEH18_RS08850	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
DEH18_RS08855	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
DEH18_RS08860	ENOG4108176	endoribonuclease L-psp
DEH18_RS08865	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
DEH18_RS08870	ENOG4105E0A	ABC, transporter
DEH18_RS08875	ENOG4108HUF	Transporter
DEH18_RS08880	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
DEH18_RS08890	ENOG4105E33	succinate dehydrogenase
DEH18_RS08915	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
DEH18_RS08920	ENOG4105CRQ	synthase (Component I)
DEH18_RS08940	ENOG4105DK0	Indole-3-glycerol phosphate synthase
DEH18_RS08950	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
DEH18_RS08955	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
DEH18_RS08965	ENOG4107TBN	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
DEH18_RS08970	ENOG4105D65	subunit l
DEH18_RS08975	ENOG4108ZE9	Monovalent cation H antiporter subunit C
DEH18_RS08980	ENOG4108JPZ	Monovalent cation H antiporter subunit D
DEH18_RS08995	ENOG4105KJM	monovalent cation h antiporter subunit g
DEH18_RS09005	ENOG4105CI0	Citrate lyase
DEH18_RS09010	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
DEH18_RS09030	ENOG41065RQ	ADP-ribosylation crystallin J1
DEH18_RS09050	ENOG4105ETE	Transcriptional regulator (LacI family
DEH18_RS09070	ENOG4105CBC	glutamate synthase
DEH18_RS09080	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
DEH18_RS09090	ENOG4108Z4X	TRANSCRIPTIONal
DEH18_RS09110	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
DEH18_RS09140	ENOG4105X1Q	TOBE domain protein
DEH18_RS09215	ENOG4105ESP	cell wall surface anchor family protein
DEH18_RS09220	ENOG4108BRW	Activates expression of the rhaSR operon in response to L-rhamnose (By similarity)
DEH18_RS09225	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
DEH18_RS09235	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
DEH18_RS09285	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
DEH18_RS09315	ENOG4108IV0	ABC, transporter
DEH18_RS09320	ENOG4105C0Z	ABC transporter
DEH18_RS09325	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
DEH18_RS09330	ENOG4105C32	Amino acid ABC transporter (Permease)
DEH18_RS09340	ENOG4105KA0	thioesterase Superfamily protein
DEH18_RS09370	ENOG4105CQ7	ATP-dependent helicase
DEH18_RS09375	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
DEH18_RS09395	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
DEH18_RS09410	ENOG4105CV8	reductase
DEH18_RS09415	ENOG4105C0D	helicase
DEH18_RS09465	ENOG4108HH4	Major Facilitator Superfamily
DEH18_RS09475	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
DEH18_RS09480	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
DEH18_RS09540	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
DEH18_RS09545	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
DEH18_RS09550	ENOG4105CHW	UPF0052 protein
DEH18_RS09555	ENOG4105CIE	May be required for sporulation (By similarity)
DEH18_RS09560	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
DEH18_RS09565	ENOG4105BZA	Phosphoglycerate kinase
DEH18_RS09570	ENOG4105CP7	Triose-phosphate isomerase
DEH18_RS09585	ENOG4107QP8	phosphohexose isomerase
DEH18_RS09595	ENOG4107XU2	6-phosphogluconolactonase (EC 3.1.1.31)
DEH18_RS09610	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
DEH18_RS09620	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
DEH18_RS09640	ENOG4105CJ1	ABC, transporter
DEH18_RS09655	ENOG4105JRK	feS assembly protein SufD
DEH18_RS09665	ENOG4105C3K	feS assembly ATPase SufC
DEH18_RS09670	ENOG4105C9B	Cysteine desulfurase
DEH18_RS09675	ENOG4108UNV	SUF system FeS assembly protein, NifU family
DEH18_RS09685	ENOG410814C	multidrug resistance protein
DEH18_RS09690	ENOG4108RFG	Tetr family transcriptional regulator
DEH18_RS09695	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
DEH18_RS09700	ENOG4105EXN	Sulfate transport protein CysZ
DEH18_RS09715	ENOG4105CUC	YeeE YedE family protein
DEH18_RS09720	ENOG4105CSH	Transporter
DEH18_RS09745	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
DEH18_RS09755	ENOG4105Y3U	Transglycosylase-associated protein
DEH18_RS09760	ENOG4105E9Z	Nad-dependent epimerase dehydratase
DEH18_RS09775	ENOG4105CJN	penicillin-binding protein
DEH18_RS09790	ENOG4105WH1	Two component transcriptional regulator luxr family
DEH18_RS09795	ENOG4108ZGX	Histidine kinase
DEH18_RS09805	ENOG4107HP6	Transcriptional regulator
DEH18_RS09825	ENOG4105EV8	ectoine hydroxylase
DEH18_RS09830	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
DEH18_RS09835	ENOG4108JPW	Aminotransferase
DEH18_RS09840	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
DEH18_RS09850	ENOG4105GRZ	Ycii-related protein
DEH18_RS09855	ENOG4105D8K	carboxyl transferase
DEH18_RS09880	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
DEH18_RS09895	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
DEH18_RS09900	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
DEH18_RS09925	ENOG4105C5H	ABC transporter
DEH18_RS09980	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
DEH18_RS09990	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
DEH18_RS10000	ENOG4107QN1	sodium solute
DEH18_RS10005	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
DEH18_RS10020	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
DEH18_RS10025	ENOG4105CHR	reductase
DEH18_RS10030	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
DEH18_RS10035	ENOG4107YCY	Transcriptional regulator
DEH18_RS10040	ENOG4105DJ2	Major Facilitator Superfamily
DEH18_RS10060	ENOG4105IDI	abc transporter atp-binding protein
DEH18_RS10075	ENOG4105WH1	Two component transcriptional regulator luxr family
DEH18_RS10095	ENOG4105DKW	ABC transporter
DEH18_RS10115	ENOG4108V1U	phospholipid-binding protein
DEH18_RS10130	ENOG4108VX5	3-methyladenine DNA glycosylase
DEH18_RS10155	ENOG4105DUU	IucA IucC family protein
DEH18_RS10165	ENOG4105F1Y	L-lysine 6-monooxygenase (NADPH)
DEH18_RS10180	ENOG4105DSU	hydrolase
DEH18_RS10185	ENOG4105Q26	Siderophore-interacting protein
DEH18_RS10195	ENOG4105DQ5	transport system permease protein
DEH18_RS10200	ENOG4105TVJ	transport system, permease
DEH18_RS10205	ENOG4105E0A	ABC, transporter
DEH18_RS10220	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
DEH18_RS10225	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
DEH18_RS10230	ENOG4108MJN	Glycosyl Transferase
DEH18_RS10235	ENOG4105ETE	Transcriptional regulator (LacI family
DEH18_RS10250	ENOG4105BZP	glycoside hydrolase 15-related
DEH18_RS10255	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
DEH18_RS10260	ENOG4108YZ4	nudix hydrolase
DEH18_RS10270	ENOG4105DCF	alanine dehydrogenase
DEH18_RS10285	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
DEH18_RS10290	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
DEH18_RS10295	ENOG4105FE9	pseudouridine synthase
DEH18_RS10310	ENOG4105CAT	Cytidine monophosphate kinase
DEH18_RS10320	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
DEH18_RS10335	ENOG4106839	domain protein
DEH18_RS10340	ENOG4108I69	Glycosyl transferases group 1
DEH18_RS10365	ENOG4105C57	major facilitator superfamily
DEH18_RS10370	ENOG4105C1G	acyl-Coa dehydrogenase
DEH18_RS10375	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
DEH18_RS10415	ENOG4105C0B	DNA polymerase III (alpha subunit)
DEH18_RS10440	ENOG4107IFA	Lipase (EC 3.1.1.3)
DEH18_RS10465	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
DEH18_RS10510	ENOG4108SHN	Glycosyl transferase, family 2
DEH18_RS10515	ENOG4106WTF	Glycosyl transferase, family 2
DEH18_RS10535	ENOG4105FDP	GntR family transcriptional regulator
DEH18_RS10540	ENOG4105F1J	Homogentisate 1,2-dioxygenase
DEH18_RS10545	ENOG4105D4T	Citrate transporter
DEH18_RS10585	ENOG4105CEY	Amp-dependent synthetase and ligase
DEH18_RS10590	ENOG4108IG5	Transcriptional regulator
DEH18_RS10595	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
DEH18_RS10605	ENOG4105C1G	acyl-Coa dehydrogenase
DEH18_RS10615	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
DEH18_RS10625	ENOG4105VG5	Membrane
DEH18_RS10630	ENOG4105PTV	Nudix Hydrolase
DEH18_RS10675	ENOG4105MRC	Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth
DEH18_RS10695	ENOG4105W2E	Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth (By similarity)
DEH18_RS10705	ENOG4107ETC	gas vesicle protein
DEH18_RS10715	ENOG4105KT7	mgtC SapB transporter
DEH18_RS10725	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
DEH18_RS10730	ENOG4105EG2	ABC transporter, permease
DEH18_RS10740	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
DEH18_RS10745	ENOG4108RFG	Tetr family transcriptional regulator
DEH18_RS10750	ENOG4105C57	major facilitator superfamily
DEH18_RS10770	ENOG4105DR5	peptidase
DEH18_RS10775	ENOG4105CNT	hydrolase family 2
DEH18_RS10780	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
DEH18_RS10785	ENOG4107TB5	TRANSCRIPTIONal
DEH18_RS10795	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
DEH18_RS10800	ENOG41082SX	arsR family transcriptional regulator
DEH18_RS10825	ENOG4105C9B	Cysteine desulfurase
DEH18_RS10830	ENOG4105ESN	nucleotide-binding protein
DEH18_RS10830	ENOG4105ESN	nucleotide-binding protein
DEH18_RS10840	ENOG4107B2H	carbonic anhydrase
DEH18_RS10850	ENOG4105DRS	transport system, permease
DEH18_RS10855	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
DEH18_RS10885	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
DEH18_RS10890	ENOG4108IJ9	(ABC) transporter
DEH18_RS10895	ENOG4105DB7	PHP domain protein
DEH18_RS10900	ENOG4105DXB	Major Facilitator superfamily
DEH18_RS10910	ENOG4105C8I	hydrolase, family 38
DEH18_RS10935	ENOG4107WCA	isomerase
DEH18_RS10965	ENOG4108NBA	ATP-dependent carboxylate-amine ligase (By similarity)
DEH18_RS10980	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
DEH18_RS10990	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
DEH18_RS11030	ENOG41079KZ	Major Facilitator Superfamily
DEH18_RS11035	ENOG4105C26	Dehydrogenase
DEH18_RS11060	ENOG4105CHR	reductase
DEH18_RS11070	ENOG4105C7K	acetolactate synthase
DEH18_RS11095	ENOG4105EMN	RNA polymerase sigma factor
DEH18_RS11100	ENOG41067HS	methyltransferase
DEH18_RS11110	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
DEH18_RS11130	ENOG4106A3M	Cytochrome p-450
DEH18_RS11150	ENOG4105C85	amino acid
DEH18_RS11185	ENOG4105EMU	Dehydrogenase
DEH18_RS11210	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
DEH18_RS11240	ENOG4105CPC	Aldo Keto reductase
DEH18_RS11245	ENOG4105DYW	oxidoreductase
DEH18_RS11255	ENOG4105D7N	magnesium and cobalt transport protein CorA
DEH18_RS11260	ENOG4108RH7	phosphoglycerate mutase
DEH18_RS11275	ENOG4105C8N	cysteinyl-tRNA synthetase
DEH18_RS11285	ENOG4105DIA	mandelate racemase muconate lactonizing
DEH18_RS11305	ENOG41071MT	Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane
DEH18_RS11310	ENOG4105JXH	GntR family transcriptional regulator
DEH18_RS11320	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
DEH18_RS11325	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
DEH18_RS11330	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
DEH18_RS11335	ENOG4108K8U	Glycerol operon regulatory protein
DEH18_RS11340	ENOG4105C3R	Methionine synthase
DEH18_RS11350	ENOG4105DEF	Extracellular solute-binding protein, family 5
DEH18_RS11355	ENOG4105WH1	Two component transcriptional regulator luxr family
DEH18_RS11380	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
DEH18_RS11385	ENOG4105E5F	proteasome
DEH18_RS11390	ENOG4105WFD	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation (By similarity)
DEH18_RS11395	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
DEH18_RS11400	ENOG4105F7N	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
DEH18_RS11405	ENOG4105ETE	Transcriptional regulator (LacI family
DEH18_RS11415	ENOG4105DVV	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine (By similarity)
DEH18_RS11430	ENOG4108FFZ	Transcriptional regulator
DEH18_RS11445	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
DEH18_RS11450	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
DEH18_RS11470	ENOG4105HFS	5'-3' exonuclease
DEH18_RS11475	ENOG4108IJ7	Glycine betaine
DEH18_RS11480	ENOG4107SQ8	Glycine betaine
DEH18_RS11510	ENOG4108Z86	Glutamine amidotransferase
DEH18_RS11515	ENOG4105CUB	amino acid
DEH18_RS11520	ENOG41073TP	transcriptional regulator
DEH18_RS11530	ENOG4105C26	Dehydrogenase
DEH18_RS11555	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
DEH18_RS11570	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
DEH18_RS11580	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
DEH18_RS11585	ENOG41084BS	50S ribosomal protein L35
DEH18_RS11590	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
DEH18_RS11595	ENOG4108RWN	rrna methyltransferase
DEH18_RS11600	ENOG4105BZU	Histidine kinase
DEH18_RS11605	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
DEH18_RS11610	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
DEH18_RS11620	ENOG41079KZ	Major Facilitator Superfamily
DEH18_RS11650	ENOG4105CPC	Aldo Keto reductase
DEH18_RS11660	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
DEH18_RS11665	ENOG4108Z40	Transcriptional regulator
DEH18_RS11670	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
DEH18_RS11675	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
DEH18_RS11680	ENOG4105CAS	nag kinase
DEH18_RS11685	ENOG4105C8Y	Acetylornithine aminotransferase
DEH18_RS11690	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
DEH18_RS11715	ENOG4105K78	MarR family Transcriptional regulator
DEH18_RS11720	ENOG4105CDH	Citrulline--aspartate ligase
DEH18_RS11725	ENOG4105CH7	arginosuccinase
DEH18_RS11745	ENOG4105C57	major facilitator superfamily
DEH18_RS11750	ENOG4105CEY	Amp-dependent synthetase and ligase
DEH18_RS11755	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
DEH18_RS11780	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
DEH18_RS11785	ENOG4108UMI	ABC transporter, permease
DEH18_RS11800	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
DEH18_RS11805	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
DEH18_RS11895	ENOG4105KF0	sporulation and cell division protein, SsgA
DEH18_RS11920	ENOG4105C22	threonyL-tRNA synthetase
DEH18_RS11945	ENOG4107YQ3	lipid a biosynthesis lauroyl acyltransferase
DEH18_RS11950	ENOG4105E2K	Glycosyl transferase (Group 1
DEH18_RS11960	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
DEH18_RS11965	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
DEH18_RS11970	ENOG4105CDY	transcriptional regulatory protein
DEH18_RS11975	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
DEH18_RS11980	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
DEH18_RS11985	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
DEH18_RS11995	ENOG4107RSV	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
DEH18_RS12000	ENOG4107RTU	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
DEH18_RS12005	ENOG41073TP	transcriptional regulator
DEH18_RS12010	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
DEH18_RS12020	ENOG41080R8	Conserved Protein
DEH18_RS12025	ENOG4107QNK	)-transporter
DEH18_RS12030	ENOG4105M10	Involved in the anomeric conversion of L-rhamnose (By similarity)
DEH18_RS12045	ENOG4105DIA	mandelate racemase muconate lactonizing
DEH18_RS12050	ENOG4105ERH	Fumarylacetoacetate hydrolase
DEH18_RS12060	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
DEH18_RS12065	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
DEH18_RS12070	ENOG4105C99	atpase involved in dna repair
DEH18_RS12075	ENOG4108ZR3	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity)
DEH18_RS12085	ENOG4105CUT	histidyl-tRNA synthetase
DEH18_RS12105	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
DEH18_RS12125	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
DEH18_RS12130	ENOG41080G3	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
DEH18_RS12140	ENOG4105E2X	shikimate dehydrogenase
DEH18_RS12145	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
DEH18_RS12150	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
DEH18_RS12155	ENOG4105D49	3-dehydroquinate synthase
DEH18_RS12165	ENOG4105DC7	peptidase M24
DEH18_RS12170	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
DEH18_RS12175	ENOG410803B	Involved in the transcription termination process (By similarity)
DEH18_RS12185	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
DEH18_RS12190	ENOG4105CXT	aspartate transcarbamylase
DEH18_RS12195	ENOG4105CD3	dihydroorotase
DEH18_RS12205	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
DEH18_RS12210	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
DEH18_RS12215	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
DEH18_RS12220	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
DEH18_RS12230	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
DEH18_RS12235	ENOG4105MTQ	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
DEH18_RS12245	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
DEH18_RS12275	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
DEH18_RS12300	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
DEH18_RS12310	ENOG4105DJV	ribulose-phosphate 3-epimerase
DEH18_RS12315	ENOG4105DKT	Transcriptional regulator
DEH18_RS12325	ENOG4107S91	Sodium hydrogen exchanger
DEH18_RS12345	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
DEH18_RS12365	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
DEH18_RS12385	ENOG4105CHR	reductase
DEH18_RS12400	ENOG4105EJ2	Transcriptional regulator
DEH18_RS12405	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
DEH18_RS12430	ENOG4105EMU	Dehydrogenase
DEH18_RS12465	ENOG4105C2W	permease
DEH18_RS12490	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
DEH18_RS12495	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
DEH18_RS12500	ENOG4105M0N	phosphoribosyl-ATP pyrophosphatase
DEH18_RS12505	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
DEH18_RS12615	ENOG4105MXW	flavin reductase domain protein, FMN-binding
DEH18_RS12620	ENOG4108KC1	acyl-Coa dehydrogenase
DEH18_RS12625	ENOG4105CIS	alcohol dehydrogenase
DEH18_RS12640	ENOG4105BZU	Histidine kinase
DEH18_RS12645	ENOG4105WH1	Two component transcriptional regulator luxr family
DEH18_RS12655	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
DEH18_RS12675	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
DEH18_RS12685	ENOG4105PWE	CRISPR-associated protein cas2
DEH18_RS12690	ENOG4105TZK	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
DEH18_RS12705	ENOG41060M0	Crispr-associated protein, cse4 family
DEH18_RS12755	ENOG4105WH1	Two component transcriptional regulator luxr family
DEH18_RS12770	ENOG4108ZHR	arsR family transcriptional regulator
DEH18_RS12790	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
DEH18_RS12795	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
DEH18_RS12800	ENOG4105GZI	Transcriptional regulator
DEH18_RS12815	ENOG4107QXN	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
DEH18_RS12820	ENOG4105C57	major facilitator superfamily
DEH18_RS12835	ENOG4105CV8	reductase
DEH18_RS12840	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
DEH18_RS12850	ENOG4105DUX	Transporter
DEH18_RS12855	ENOG4107VFR	oxidoreductase
DEH18_RS12890	ENOG4108Z6Z	Transcriptional regulator
DEH18_RS12905	ENOG4108X07	Tetr family transcriptional regulator
DEH18_RS12910	ENOG4105EN6	Membrane
DEH18_RS12915	ENOG41066UM	arsR family transcriptional regulator
DEH18_RS12930	ENOG4105CHR	reductase
DEH18_RS12960	ENOG4107YCY	Transcriptional regulator
DEH18_RS12970	ENOG4105CEY	Amp-dependent synthetase and ligase
DEH18_RS12980	ENOG4105CEY	Amp-dependent synthetase and ligase
DEH18_RS12985	ENOG4105CC9	acyl-Coa dehydrogenase
DEH18_RS12995	ENOG4105D2B	acyl-CoA dehydrogenase
DEH18_RS13000	ENOG4106YT9	Enoyl-CoA hydratase
DEH18_RS13005	ENOG4105X7H	acyl-CoA dehydrogenase
DEH18_RS13010	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
DEH18_RS13065	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
DEH18_RS13075	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
DEH18_RS13080	ENOG4105JHE	Major Facilitator Superfamily
DEH18_RS13085	ENOG4105CHR	reductase
DEH18_RS13110	ENOG4105CSH	Transporter
DEH18_RS13115	ENOG4106YKD	Cytochrome p-450
DEH18_RS13155	ENOG4108QIU	Dehydrogenase
DEH18_RS13160	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
DEH18_RS13185	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
DEH18_RS13205	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
DEH18_RS13260	ENOG4105CPQ	Dehydrogenase
DEH18_RS13265	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
DEH18_RS13285	ENOG4108IUE	nitrate reductase beta subunit
DEH18_RS13305	ENOG41083TI	Protein CrcB homolog
DEH18_RS13310	ENOG4105KJJ	Uncharacterized ACR, COG1993
DEH18_RS13350	ENOG4105CGD	Nad-dependent epimerase dehydratase
DEH18_RS13355	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
DEH18_RS13375	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
DEH18_RS13380	ENOG4105C26	Dehydrogenase
DEH18_RS13415	ENOG4108QYW	Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture. Beta-hemolysin is a phospholipase C with specific activity toward sphingomyelins. Has a high specificity for sphingomyelin, hydrolyzes lysophosphatidylcholine at a much lower rate, but has no activity towards phosphatidylcholine, phosphatidylethanolamine, or phosphatidylserine (By similarity)
DEH18_RS13450	ENOG4105CPF	Cell wall formation (By similarity)
DEH18_RS13455	ENOG4105C2W	permease
DEH18_RS13465	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
DEH18_RS13470	ENOG4108UZX	fmn reductase
DEH18_RS13480	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
DEH18_RS13500	ENOG410635A	Membrane
DEH18_RS13515	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
DEH18_RS13555	ENOG4108IAJ	Nad-dependent epimerase dehydratase
DEH18_RS13585	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
DEH18_RS13595	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
DEH18_RS13600	ENOG4105DKP	glycosyl transferase, family 9
DEH18_RS13635	ENOG4105EMU	Dehydrogenase
DEH18_RS13655	ENOG4105X7H	acyl-CoA dehydrogenase
DEH18_RS13690	ENOG4105E39	Enoyl-CoA hydratase
DEH18_RS13770	ENOG4105CFM	UPF0317 protein
DEH18_RS13775	ENOG4107RGD	Major Facilitator superfamily
DEH18_RS13805	ENOG4105GWZ	Roadblock lc7 family protein
DEH18_RS13820	ENOG4108UQS	dipeptidase
DEH18_RS13835	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
DEH18_RS13840	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
DEH18_RS13910	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
DEH18_RS13920	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DEH18_RS13950	ENOG4107U9T	Pfam:Ribonuclease_BN
DEH18_RS13955	ENOG4105NTW	Transcriptional regulator
DEH18_RS13965	ENOG41069M3	Transcriptional regulator
DEH18_RS13970	ENOG4105CYF	SMP-30 gluconolaconase LRE domain protein
DEH18_RS13975	ENOG4108HWW	ABC transporter
DEH18_RS14000	ENOG4105CXK	mandelate racemase muconate lactonizing
DEH18_RS14015	ENOG4105CSW	GntR family transcriptional regulator
DEH18_RS14035	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
DEH18_RS14045	ENOG4107RSM	transcriptional regulator
DEH18_RS14050	ENOG4108K8S	endonuclease I
DEH18_RS14060	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
DEH18_RS14075	ENOG4108DZ7	Serine Threonine protein kinase
DEH18_RS14170	ENOG4105CHR	reductase
DEH18_RS14175	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
DEH18_RS14235	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
DEH18_RS14245	ENOG4108ARV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
DEH18_RS14270	ENOG4108Z0R	Transferase
DEH18_RS14275	ENOG4108UW5	maltose o-acetyltransferase
DEH18_RS14295	ENOG4105K4P	CoA-binding domain protein
DEH18_RS14300	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
DEH18_RS14310	ENOG4105EYH	Exonuclease
DEH18_RS14340	ENOG4105PMW	Domain of unknown function (DUF1990)
DEH18_RS14360	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
DEH18_RS14365	ENOG4108KPJ	rna polymerase sigma factor
DEH18_RS14370	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
DEH18_RS14375	ENOG4105FDP	GntR family transcriptional regulator
DEH18_RS14380	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
DEH18_RS14385	ENOG4108VCA	G U mismatch-specific DNA glycosylase
DEH18_RS14390	ENOG4105C83	adenylosuccinate lyase
DEH18_RS14420	ENOG4107WHG	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
DEH18_RS14425	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
DEH18_RS14430	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
DEH18_RS14435	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
DEH18_RS14440	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
DEH18_RS14460	ENOG4105IIU	Aminopeptidase
DEH18_RS14465	ENOG4108YZ9	Urea amidohydrolase subunit gamma
DEH18_RS14470	ENOG4105KI2	Urea amidohydrolase subunit beta
DEH18_RS14475	ENOG4105CQM	Urea amidohydrolase subunit alpha
DEH18_RS14485	ENOG4107S16	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
DEH18_RS14495	ENOG4106JDR	secreted
DEH18_RS14505	ENOG4105F6E	Acyl-transferase
DEH18_RS14530	ENOG4108Z0Z	intracellular protease Pfpi family
DEH18_RS14540	ENOG4105F1K	Glutamine amidotransferase
DEH18_RS14550	ENOG4107ZWG	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
DEH18_RS14560	ENOG4105C1G	acyl-Coa dehydrogenase
DEH18_RS14565	ENOG4105C5R	Aminotransferase
DEH18_RS14575	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
DEH18_RS14600	ENOG4105BZU	Histidine kinase
DEH18_RS14605	ENOG4105WH1	Two component transcriptional regulator luxr family
DEH18_RS14615	ENOG4105ETE	Transcriptional regulator (LacI family
DEH18_RS14630	ENOG4105I1F	Resistance protein
DEH18_RS14640	ENOG4107PP3	Acetylornithine deacetylase
DEH18_RS14660	ENOG4105CPC	Aldo Keto reductase
DEH18_RS14675	ENOG4105EMU	Dehydrogenase
DEH18_RS14695	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
DEH18_RS14700	ENOG4105XYF	acetyltransferase
DEH18_RS14705	ENOG4105BZU	Histidine kinase
DEH18_RS14710	ENOG4105WH1	Two component transcriptional regulator luxr family
DEH18_RS14730	ENOG4105MVE	transcriptional regulator
DEH18_RS14740	ENOG4106F1P	AAA ATPase, central domain protein
DEH18_RS14750	ENOG4107QRI	Phosphoketolase
DEH18_RS14755	ENOG4107RR1	TRANSCRIPTIONal
DEH18_RS14760	ENOG4105C26	Dehydrogenase
DEH18_RS14785	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
DEH18_RS14790	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
DEH18_RS14800	ENOG4105BZU	Histidine kinase
DEH18_RS14805	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
DEH18_RS14810	ENOG4105C3M	thioredoxin reductase
DEH18_RS14830	ENOG4105K64	Glycosyl transferase, family 2
DEH18_RS14850	ENOG4108UTZ	Dihydroxyacetone kinase
DEH18_RS14855	ENOG4105CMT	Dihydroxyacetone kinase
DEH18_RS14870	ENOG41061H0	Monooxygenase
DEH18_RS14890	ENOG4105EMU	Dehydrogenase
DEH18_RS14895	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
DEH18_RS14935	ENOG4106IBS	oxygenase
DEH18_RS14940	ENOG4105WQT	MbtH domain protein
DEH18_RS14945	ENOG4105CIH	Imidazole acetol-phosphate transaminase
DEH18_RS14970	ENOG4108RKS	Short-chain dehydrogenase reductase Sdr
DEH18_RS14995	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
DEH18_RS15035	ENOG4107RCH	Diaminopropionate ammonia-lyase
DEH18_RS15040	ENOG4105G2Y	Transcriptional regulator
DEH18_RS15045	ENOG4105ECY	inositol monophosphatase
DEH18_RS15065	ENOG4105KVH	Transcriptional regulator
DEH18_RS15105	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
DEH18_RS15120	ENOG4105CZN	Potassium uptake protein
DEH18_RS15130	ENOG4105DVW	rieske (2Fe-2S)
DEH18_RS15135	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
DEH18_RS15160	ENOG4105FQP	Beta-lactamase
DEH18_RS15175	ENOG4108RQ5	Beta-lactamase domain-containing protein
DEH18_RS15190	ENOG4105CHH	sulfate transporter
DEH18_RS15195	ENOG4108Z6Z	Transcriptional regulator
DEH18_RS15200	ENOG4105ECQ	AraC Family Transcriptional Regulator
DEH18_RS15225	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
DEH18_RS15230	ENOG4107SET	aldo keto reductase
DEH18_RS15250	ENOG4105CSW	GntR family transcriptional regulator
DEH18_RS15255	ENOG4105CMT	Dihydroxyacetone kinase
DEH18_RS15260	ENOG4108UTZ	Dihydroxyacetone kinase
DEH18_RS15265	ENOG4105E1F	short-chain dehydrogenase reductase
DEH18_RS15270	ENOG4107VXZ	Hydrolase
DEH18_RS15280	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
DEH18_RS15285	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
DEH18_RS15290	ENOG4105WH1	Two component transcriptional regulator luxr family
DEH18_RS15295	ENOG4105BZU	Histidine kinase
DEH18_RS15315	ENOG4105E8R	UPF0173 metal-dependent hydrolase
DEH18_RS15340	ENOG41090KQ	Glyoxalase Bleomycin resistance protein (Dioxygenase
DEH18_RS15345	ENOG4105NPE	arsR family transcriptional regulator
DEH18_RS15390	ENOG4105CFG	Acts as a chaperone (By similarity)
DEH18_RS15395	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DEH18_RS15425	ENOG4108HR6	Dehydrogenase
DEH18_RS15430	ENOG4105C7W	Xanthine dehydrogenase
DEH18_RS15455	ENOG4107R13	MMPL domain protein
DEH18_RS15520	ENOG4105F1Y	L-lysine 6-monooxygenase (NADPH)
DEH18_RS15545	ENOG4105C5Q	Transcriptional regulator
DEH18_RS15575	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
DEH18_RS15580	ENOG4105C2M	dna polymerase I
DEH18_RS15585	ENOG4108V62	Rhodanese domain protein
DEH18_RS15590	ENOG4105XTG	Pfam:DUF156
DEH18_RS15595	ENOG4108VCT	Sulfite exporter TauE/SafE
DEH18_RS15610	ENOG41060BG	Tetr family transcriptional regulator
DEH18_RS15625	ENOG4105C1G	acyl-Coa dehydrogenase
DEH18_RS15670	ENOG4105EW9	transcriptional regulator AsnC family
DEH18_RS15675	ENOG4105CI2	imidazolone-5-propionate hydrolase
DEH18_RS15685	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
DEH18_RS15695	ENOG4105Q70	
DEH18_RS15700	ENOG4105DEU	major facilitator superfamily
DEH18_RS15715	ENOG4107S5I	aldo keto reductase
DEH18_RS15720	ENOG4107RSM	transcriptional regulator
DEH18_RS15775	ENOG4105ETS	cytosine purines uracil thiamine allantoin
DEH18_RS15780	ENOG4105GZI	Transcriptional regulator
DEH18_RS15805	ENOG4108TVX	serine protease
DEH18_RS15820	ENOG4107S9F	NmrA family
DEH18_RS15825	ENOG4105E39	Enoyl-CoA hydratase
DEH18_RS15835	ENOG4105C1G	acyl-Coa dehydrogenase
DEH18_RS15840	ENOG4105F35	Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity)
DEH18_RS15850	ENOG4105FQP	Beta-lactamase
DEH18_RS15870	ENOG4106A3M	Cytochrome p-450
DEH18_RS15890	ENOG4105ETE	Transcriptional regulator (LacI family
DEH18_RS15915	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
DEH18_RS15970	ENOG4105WH1	Two component transcriptional regulator luxr family
DEH18_RS15995	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
DEH18_RS16005	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
DEH18_RS16050	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
DEH18_RS16100	ENOG4108QIU	Dehydrogenase
DEH18_RS16110	ENOG4105H3G	oxidoreductase
DEH18_RS16115	ENOG4105KME	endoribonuclease L-psp
DEH18_RS16130	ENOG4108IJ0	Aspartate ammonia-lyase
DEH18_RS16135	ENOG4105CSH	Transporter
DEH18_RS16140	ENOG4105C5Q	Transcriptional regulator
DEH18_RS16150	ENOG4105ETS	cytosine purines uracil thiamine allantoin
DEH18_RS16155	ENOG4105C26	Dehydrogenase
DEH18_RS16160	ENOG4107S4Y	M20 DapE family protein YgeY
DEH18_RS16165	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
DEH18_RS16170	ENOG4105E5D	amino acid
DEH18_RS16180	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
DEH18_RS16190	ENOG4106NZI	LysR family Transcriptional regulator
DEH18_RS16215	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
DEH18_RS16220	ENOG4105ETE	Transcriptional regulator (LacI family
DEH18_RS16225	ENOG4105C4C	beta-galactosidase
DEH18_RS16260	ENOG4105C54	Major Facilitator superfamily
DEH18_RS16270	ENOG4105CIR	epoxide hydrolase
DEH18_RS16290	ENOG4108XFH	Transcriptional regulator
DEH18_RS16300	ENOG4108PSK	reductase
DEH18_RS16320	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
DEH18_RS16365	ENOG4105CPC	Aldo Keto reductase
DEH18_RS16375	ENOG4105WH1	Two component transcriptional regulator luxr family
DEH18_RS16395	ENOG4108R86	Transcriptional regulator
DEH18_RS16405	ENOG4108V7B	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity)
DEH18_RS16415	ENOG4105BZ9	Cytochrome C oxidase, subunit I
DEH18_RS16430	ENOG4105DTQ	mandelate racemase muconate lactonizing
DEH18_RS16440	ENOG4105CUB	amino acid
DEH18_RS16460	ENOG4105DRR	Transcriptional regulator, GntR family
DEH18_RS16490	ENOG4105EQ0	Major Facilitator superfamily
DEH18_RS16505	ENOG4108WUH	Transcriptional regulator, TetR family
DEH18_RS16525	ENOG4105DUM	transcriptional regulator, lysR family
DEH18_RS16530	ENOG4105C1G	acyl-Coa dehydrogenase
DEH18_RS16535	ENOG410846T	CoA-transferase family III
DEH18_RS16575	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
DEH18_RS16590	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
DEH18_RS16615	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
DEH18_RS16635	ENOG4105C26	Dehydrogenase
DEH18_RS16640	ENOG4105CEY	Amp-dependent synthetase and ligase
DEH18_RS16650	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DEH18_RS16715	ENOG4105WH1	Two component transcriptional regulator luxr family
DEH18_RS16725	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
DEH18_RS16730	ENOG4105CHR	reductase
DEH18_RS16770	ENOG4105DA5	(ABC) transporter
DEH18_RS16775	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
DEH18_RS16810	ENOG4107RSM	transcriptional regulator
DEH18_RS16830	ENOG4105MSY	salicylate hydroxylase
DEH18_RS16880	ENOG4105CBD	Diacylglycerol kinase
DEH18_RS16895	ENOG4105DVW	rieske (2Fe-2S)
DEH18_RS16920	ENOG4105ERH	Fumarylacetoacetate hydrolase
DEH18_RS16935	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
DEH18_RS16940	ENOG4107Z3H	Transcriptional regulator, TetR family
DEH18_RS16965	ENOG41067TZ	transcriptional regulator, MarR family
DEH18_RS16970	ENOG4106F1P	AAA ATPase, central domain protein
DEH18_RS17020	ENOG4105EC2	ftsk spoIIIe
DEH18_RS17030	ENOG4105CIR	epoxide hydrolase
DEH18_RS17045	ENOG4106NZI	LysR family Transcriptional regulator
DEH18_RS17050	ENOG4105CSH	Transporter
DEH18_RS17060	ENOG4107QVI	Methyltransferase, type 11
DEH18_RS17095	ENOG4108VW9	Membrane
DEH18_RS17115	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
DEH18_RS17125	ENOG4105BZ1	(ABC) transporter
DEH18_RS17145	ENOG4105MXW	flavin reductase domain protein, FMN-binding
DEH18_RS17150	ENOG4108KC1	acyl-Coa dehydrogenase
DEH18_RS17170	ENOG4105CPC	Aldo Keto reductase
DEH18_RS17185	ENOG4105ERH	Fumarylacetoacetate hydrolase
DEH18_RS17200	ENOG41061H0	Monooxygenase
DEH18_RS17220	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
DEH18_RS17225	ENOG4108IND	Tetr family transcriptional regulator
DEH18_RS17235	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
DEH18_RS17255	ENOG4108RKS	Short-chain dehydrogenase reductase Sdr
DEH18_RS17265	ENOG4108UU4	oxidoreductase (Short chain dehydrogenase reductase family)
DEH18_RS17280	ENOG4108UW5	maltose o-acetyltransferase
DEH18_RS17290	ENOG4108JJB	ABC transporter
DEH18_RS17295	ENOG4105BZ1	(ABC) transporter
DEH18_RS17340	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
DEH18_RS17345	ENOG4105CPC	Aldo Keto reductase
DEH18_RS17355	ENOG4108RZE	Tetr family transcriptional regulator
DEH18_RS17405	ENOG4105EBM	Alpha Beta Hydrolase Fold protein
DEH18_RS17410	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
DEH18_RS17445	ENOG4107RGD	Major Facilitator superfamily
DEH18_RS17465	ENOG4105CM2	brancheD-chain amino acid aminotransferase
DEH18_RS17480	ENOG4107TYG	Oxidoreductase domain-containing protein
DEH18_RS17485	ENOG4108HHA	Transketolase
DEH18_RS17490	ENOG4108IUS	Transketolase
DEH18_RS17510	ENOG4105CEY	Amp-dependent synthetase and ligase
DEH18_RS17520	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
DEH18_RS17525	ENOG4105CHR	reductase
DEH18_RS17530	ENOG4108URH	decarboxylase
DEH18_RS17535	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
DEH18_RS17545	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
DEH18_RS17550	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
DEH18_RS17555	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
DEH18_RS17565	ENOG4105WH1	Two component transcriptional regulator luxr family
DEH18_RS17580	ENOG4105E1F	short-chain dehydrogenase reductase
DEH18_RS17600	ENOG4105CHR	reductase
DEH18_RS17650	ENOG4105CH7	arginosuccinase
DEH18_RS17655	ENOG4105JZC	GHMP kinase
DEH18_RS17660	ENOG410880H	cysteine synthase
DEH18_RS17760	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
DEH18_RS17770	ENOG4105DIV	Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds (By similarity)
DEH18_RS17795	ENOG4106IBS	oxygenase
DEH18_RS17825	ENOG41068WN	
DEH18_RS17855	ENOG4105ECQ	AraC Family Transcriptional Regulator
DEH18_RS17890	ENOG41068WN	
DEH18_RS17910	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
DEH18_RS17915	ENOG4105C0W	non-ribosomal peptide synthetase
DEH18_RS17930	ENOG4105CEY	Amp-dependent synthetase and ligase
DEH18_RS17935	ENOG4105C0W	non-ribosomal peptide synthetase
DEH18_RS17950	ENOG4107SQU	synthase
DEH18_RS17985	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
DEH18_RS17990	ENOG4105F8D	glycoside hydrolase family 4
DEH18_RS18000	ENOG4105DRS	transport system, permease
DEH18_RS18005	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
DEH18_RS18010	ENOG4107FKK	extracellular solute-binding protein family 1
DEH18_RS18030	ENOG4105EUF	amidase EC 3.5.1.4
DEH18_RS18080	ENOG4105C5W	Aldolase
DEH18_RS18110	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
DEH18_RS18115	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
DEH18_RS18120	ENOG4105ETE	Transcriptional regulator (LacI family
DEH18_RS18130	ENOG4105CPN	adenine deaminase
DEH18_RS18145	ENOG4105C10	Electron transfer flavoprotein
DEH18_RS18170	ENOG4105CAQ	asparagine synthetase
DEH18_RS18195	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
DEH18_RS18250	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
DEH18_RS18265	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
DEH18_RS18270	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
DEH18_RS18280	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
DEH18_RS18295	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
DEH18_RS18305	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
DEH18_RS18315	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
DEH18_RS18325	ENOG4105C2W	permease
DEH18_RS18330	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
DEH18_RS18335	ENOG4105CKI	cobalamin synthesis protein
DEH18_RS18340	ENOG4105VPX	protein, conserved in bacteria
DEH18_RS18345	ENOG4105E6M	Sulphatase-modifying factor protein
DEH18_RS18350	ENOG4105CBG	Sulfatase
DEH18_RS18355	ENOG41061DF	Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P (By similarity)
DEH18_RS18370	ENOG4107UWC	ABC, transporter
DEH18_RS18400	ENOG4105FDP	GntR family transcriptional regulator
DEH18_RS18430	ENOG4105IE8	Alpha-ketoglutarate permease
DEH18_RS18440	ENOG4105C0W	non-ribosomal peptide synthetase
DEH18_RS18455	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
DEH18_RS18460	ENOG4106A3M	Cytochrome p-450
DEH18_RS18470	ENOG4105CAQ	asparagine synthetase
DEH18_RS18475	ENOG4107SWE	Methyltransferase
DEH18_RS18495	ENOG4105C0W	non-ribosomal peptide synthetase
DEH18_RS18525	ENOG4108JJB	ABC transporter
DEH18_RS18530	ENOG4105BZ1	(ABC) transporter
DEH18_RS18550	ENOG4105DA5	(ABC) transporter
DEH18_RS18590	ENOG4108Z40	Transcriptional regulator
DEH18_RS18600	ENOG4105F95	Monooxygenase
DEH18_RS18615	ENOG4105SKE	transcriptional Regulator LysR family
DEH18_RS18635	ENOG4108I69	Glycosyl transferases group 1
DEH18_RS18645	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
DEH18_RS18655	ENOG4105VZ8	Transcriptional regulator
DEH18_RS18690	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
DEH18_RS18710	ENOG4105K64	Glycosyl transferase, family 2
DEH18_RS18720	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
DEH18_RS18745	ENOG4105WH1	Two component transcriptional regulator luxr family
DEH18_RS18765	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
DEH18_RS18770	ENOG4105EJ2	Transcriptional regulator
DEH18_RS18800	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
DEH18_RS18845	ENOG4105C85	amino acid
DEH18_RS18850	ENOG4108ME1	Peptidase M55 D-aminopeptidase
DEH18_RS18855	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
DEH18_RS18860	ENOG4108K8K	Transcriptional regulator
DEH18_RS18860	ENOG4108K8K	Transcriptional regulator
DEH18_RS18870	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
DEH18_RS18875	ENOG41069M3	Transcriptional regulator
DEH18_RS18885	ENOG4106HB6	Alpha beta hydrolase
DEH18_RS18910	ENOG4107HP6	Transcriptional regulator
DEH18_RS18925	ENOG4108IGT	Dipeptidase
DEH18_RS18955	ENOG4106A3M	Cytochrome p-450
DEH18_RS18960	ENOG4105WH1	Two component transcriptional regulator luxr family
DEH18_RS18965	ENOG4105BZU	Histidine kinase
DEH18_RS18975	ENOG4107RN3	metallophosphoesterase
DEH18_RS18980	ENOG4105FS7	Transcriptional regulator
DEH18_RS18995	ENOG4107ZED	Uncharacterised protein family UPF0047
DEH18_RS19000	ENOG4105H3G	oxidoreductase
DEH18_RS19005	ENOG4105ETE	Transcriptional regulator (LacI family
DEH18_RS19015	ENOG4105F5R	ABC transporter
DEH18_RS19025	ENOG4105C2J	ABC transporter
DEH18_RS19035	ENOG4105DET	Rhamnulokinase
DEH18_RS19050	ENOG4105DKW	ABC transporter
DEH18_RS19065	ENOG4105EHZ	conserved protein UCP016719
DEH18_RS19075	ENOG4105BZ1	(ABC) transporter
DEH18_RS19085	ENOG4105CQB	FAD linked oxidase domain protein
DEH18_RS19105	ENOG4105BZ1	(ABC) transporter
DEH18_RS19110	ENOG4105BZ1	(ABC) transporter
DEH18_RS19125	ENOG4105C29	acyl-CoA thioesterase
DEH18_RS19135	ENOG4105GWZ	Roadblock lc7 family protein
DEH18_RS19160	ENOG4105C0D	helicase
DEH18_RS19215	ENOG41086IN	PA14
DEH18_RS19220	ENOG4105CEY	Amp-dependent synthetase and ligase
DEH18_RS19225	ENOG4105DEN	Luciferase family
DEH18_RS19230	ENOG4105WH1	Two component transcriptional regulator luxr family
DEH18_RS19250	ENOG4107R8N	Glycosyl transferase, family 2
DEH18_RS19275	ENOG4105VEQ	Cold shock protein
DEH18_RS19290	ENOG4105E98	transcriptional regulator DeoR family
DEH18_RS19310	ENOG4105CPQ	Dehydrogenase
DEH18_RS19330	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
DEH18_RS19365	ENOG4108IV0	ABC, transporter
DEH18_RS19370	ENOG4105C2J	ABC transporter
DEH18_RS19395	ENOG4105C8S	subunit m
DEH18_RS19400	ENOG4105MKQ	Monovalent cation H antiporter subunit C
DEH18_RS19425	ENOG4105CXN	decarboxylase
DEH18_RS19430	ENOG4107TRG	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair (By similarity)
DEH18_RS19435	ENOG4105DQE	DNA ligase
DEH18_RS19460	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
DEH18_RS19490	ENOG4107R37	Glutamate dehydrogenase
DEH18_RS19525	ENOG4105CHF	Glutathione S-transferase
DEH18_RS19560	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
DEH18_RS19600	ENOG4105C57	major facilitator superfamily
DEH18_RS19610	ENOG4105E98	transcriptional regulator DeoR family
DEH18_RS19615	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
DEH18_RS19625	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
DEH18_RS19630	ENOG4105CPQ	Dehydrogenase
DEH18_RS19645	ENOG4105DRS	transport system, permease
DEH18_RS19685	ENOG41082YX	Transcriptional regulator, arsr family
DEH18_RS19690	ENOG4105H3G	oxidoreductase
DEH18_RS19710	ENOG4108UW5	maltose o-acetyltransferase
DEH18_RS19715	ENOG4105C5H	ABC transporter
DEH18_RS19720	ENOG4107QNK	)-transporter
DEH18_RS19725	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
DEH18_RS19730	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
DEH18_RS19760	ENOG4105ETE	Transcriptional regulator (LacI family
DEH18_RS19775	ENOG4105GYP	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity)
DEH18_RS19780	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
DEH18_RS19785	ENOG4108ZVT	methylmalonyl-coA epimerase
DEH18_RS19790	ENOG4105D5P	Methylmalonyl-coA mutase
DEH18_RS19810	ENOG4105CEY	Amp-dependent synthetase and ligase
DEH18_RS19820	ENOG4105CAQ	asparagine synthetase
DEH18_RS19825	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
DEH18_RS19860	ENOG4108Z4X	TRANSCRIPTIONal
DEH18_RS19905	ENOG4105VQD	rieske 2fe-2S domain-containing protein
DEH18_RS19910	ENOG4105J4Q	Transcriptional regulator
DEH18_RS19925	ENOG4105F76	Sarcosine oxidase
DEH18_RS19930	ENOG4105DVW	rieske (2Fe-2S)
DEH18_RS19985	ENOG41073TP	transcriptional regulator
DEH18_RS19990	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
DEH18_RS20010	ENOG4105E1V	na solute symporter
DEH18_RS20045	ENOG4105CHR	reductase
DEH18_RS20075	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
DEH18_RS20080	ENOG4105PGM	cation diffusion facilitator family transporter
DEH18_RS20090	ENOG4108YYC	ycei family
DEH18_RS20100	ENOG4105D44	asparaginase
DEH18_RS20105	ENOG4105C1G	acyl-Coa dehydrogenase
DEH18_RS20110	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
DEH18_RS20115	ENOG4107RSM	transcriptional regulator
DEH18_RS20120	ENOG4105CHU	acetyl-coa acetyltransferase
DEH18_RS20145	ENOG4105CEY	Amp-dependent synthetase and ligase
DEH18_RS20150	ENOG4108UB4	uncharacterized protein ygjQ
DEH18_RS20155	ENOG41080RH	Thioredoxin
DEH18_RS20160	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
DEH18_RS20180	ENOG4107RYT	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair (By similarity)
DEH18_RS20195	ENOG4105WH1	Two component transcriptional regulator luxr family
DEH18_RS20205	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
DEH18_RS20230	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
DEH18_RS20240	ENOG4105K59	histidine triad (HIT) protein
DEH18_RS20245	ENOG4105CV8	reductase
DEH18_RS20250	ENOG4105ETS	cytosine purines uracil thiamine allantoin
DEH18_RS20255	ENOG4108YV4	Universal stress protein
DEH18_RS20260	ENOG4105CPQ	Dehydrogenase
DEH18_RS20280	ENOG4105EEM	helicase
DEH18_RS20330	ENOG4105CSU	acyl-Coa dehydrogenase
DEH18_RS20335	ENOG4108KGH	TRANSCRIPTIONal
DEH18_RS20355	ENOG4105EFJ	Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity)
DEH18_RS20360	ENOG4105C3U	ABC transporter
DEH18_RS20365	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
DEH18_RS20385	ENOG4105BZU	Histidine kinase
DEH18_RS20400	ENOG4105C1G	acyl-Coa dehydrogenase
DEH18_RS20420	ENOG4105GWZ	Roadblock lc7 family protein
DEH18_RS20445	ENOG4107R7Y	intracellular protease Pfpi family
DEH18_RS20475	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
DEH18_RS20490	ENOG4105EWU	Squalene--hopene cyclase
DEH18_RS20500	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
DEH18_RS20510	ENOG4105FBD	synthase
DEH18_RS20520	ENOG4107R13	MMPL domain protein
DEH18_RS20525	ENOG4105EY8	ABC transporter
DEH18_RS20545	ENOG4105C0A	alcohol dehydrogenase
DEH18_RS20565	ENOG4108ZEY	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
DEH18_RS20575	ENOG4105E39	Enoyl-CoA hydratase
DEH18_RS20585	ENOG4105BZM	domain protein
DEH18_RS20590	ENOG4108RCM	Nitroreductase
DEH18_RS20635	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
DEH18_RS20640	ENOG4105CHU	acetyl-coa acetyltransferase
DEH18_RS20645	ENOG4105C1G	acyl-Coa dehydrogenase
DEH18_RS20650	ENOG410846T	CoA-transferase family III
DEH18_RS20655	ENOG4105C57	major facilitator superfamily
DEH18_RS20670	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
DEH18_RS20675	ENOG4105D2N	Aldolase
DEH18_RS20680	ENOG4105E98	transcriptional regulator DeoR family
DEH18_RS20695	ENOG4107YXZ	hydrolase, family 25
DEH18_RS20715	ENOG4105EG6	Saccharopine dehydrogenase
DEH18_RS20720	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
DEH18_RS20725	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
DEH18_RS20730	ENOG4105CHR	reductase
DEH18_RS20740	ENOG4105CEY	Amp-dependent synthetase and ligase
DEH18_RS20750	ENOG4105K5B	UPF0225 protein
DEH18_RS20780	ENOG4105EQN	UPF0261 protein
DEH18_RS20785	ENOG4105DAA	L-lactate
DEH18_RS20795	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
DEH18_RS20820	ENOG4105C6F	GntR Family Transcriptional Regulator
DEH18_RS20825	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
DEH18_RS20830	ENOG4105C6Z	Gluconate
DEH18_RS20840	ENOG4105DDW	LysR family Transcriptional regulator
DEH18_RS20865	ENOG4105C3W	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity)
DEH18_RS20880	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
DEH18_RS20890	ENOG4105CR4	methylisocitrate lyase
DEH18_RS20900	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
DEH18_RS20905	ENOG4108BAS	reductase
DEH18_RS20930	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
DEH18_RS20935	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
DEH18_RS20940	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
DEH18_RS20945	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
DEH18_RS20995	ENOG4107T3P	ABC, transporter
DEH18_RS21005	ENOG4105M2Z	protein tyrosine serine phosphatase
DEH18_RS21010	ENOG4108VQR	secreted hydrolase
DEH18_RS21045	ENOG4108AQF	aminoglycoside N(3)-acetyltransferase
DEH18_RS21050	ENOG4105NRA	50s ribosomal protein l31 type b
DEH18_RS21055	ENOG4105KDC	50s ribosomal protein l28
DEH18_RS21060	ENOG41080FR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
DEH18_RS21085	ENOG4105ETS	cytosine purines uracil thiamine allantoin
DEH18_RS21090	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
DEH18_RS21105	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
DEH18_RS21110	ENOG4105C6Z	Gluconate
DEH18_RS21130	ENOG4105BZP	glycoside hydrolase 15-related
DEH18_RS21135	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
DEH18_RS21145	ENOG4105DIA	mandelate racemase muconate lactonizing
DEH18_RS21150	ENOG4105CQB	FAD linked oxidase domain protein
DEH18_RS21165	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
DEH18_RS21175	ENOG4105C1G	acyl-Coa dehydrogenase
DEH18_RS21185	ENOG4105CXK	mandelate racemase muconate lactonizing
DEH18_RS21190	ENOG4105I1K	ABC transporter
DEH18_RS21200	ENOG4105XN3	extracellular solute-binding protein family 1
DEH18_RS21205	ENOG4105C4C	beta-galactosidase
DEH18_RS21210	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
DEH18_RS21215	ENOG4105JXH	GntR family transcriptional regulator
DEH18_RS21230	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
DEH18_RS21235	ENOG4107EJG	GntR family transcriptional regulator
DEH18_RS21240	ENOG4108KD5	ADP-ribosylation crystallin J1
DEH18_RS21260	ENOG4105QAX	Iron-sulfur
DEH18_RS21270	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
DEH18_RS21275	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
DEH18_RS21280	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
DEH18_RS21295	ENOG4105EM7	Selenocysteine-specific translation elongation factor
DEH18_RS21300	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
DEH18_RS21310	ENOG4105BZ9	Cytochrome C oxidase, subunit I
DEH18_RS21330	ENOG4105CEY	Amp-dependent synthetase and ligase
DEH18_RS21360	ENOG4106C1H	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Activated D-alanyl-Dcp donates its D-alanyl substituent to membrane-associated LTA (By similarity)
DEH18_RS21365	ENOG4105CPQ	Dehydrogenase
DEH18_RS21415	ENOG41069H0	dihydroorotase EC 3.5.2.3
DEH18_RS21420	ENOG41069M3	Transcriptional regulator
DEH18_RS21480	ENOG4107S1E	Beta-lactamase
DEH18_RS21515	ENOG4108EKI	Dehydrogenase
DEH18_RS21530	ENOG4105C5I	Dehydrogenase
DEH18_RS21545	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
DEH18_RS21555	ENOG41060WC	Enoyl-CoA hydratase
DEH18_RS21570	ENOG4105EA8	2-Nitropropane dioxygenase
DEH18_RS21575	ENOG4105F2C	Acetyl-CoA acetyltransferase
DEH18_RS21580	ENOG4108RZE	Tetr family transcriptional regulator
DEH18_RS21585	ENOG4105CHR	reductase
DEH18_RS21590	ENOG4105CC9	acyl-Coa dehydrogenase
DEH18_RS21600	ENOG4105CC9	acyl-Coa dehydrogenase
DEH18_RS21605	ENOG4105C1G	acyl-Coa dehydrogenase
DEH18_RS21610	ENOG4105D2B	acyl-CoA dehydrogenase
DEH18_RS21625	ENOG4105CNA	YD repeat protein
DEH18_RS21650	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
DEH18_RS21660	ENOG4105CEY	Amp-dependent synthetase and ligase
DEH18_RS21665	ENOG4105MXW	flavin reductase domain protein, FMN-binding
DEH18_RS21675	ENOG4108M8W	Monooxygenase
DEH18_RS21690	ENOG4105M2Z	protein tyrosine serine phosphatase
DEH18_RS21695	ENOG4108KC1	acyl-Coa dehydrogenase
DEH18_RS21730	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
DEH18_RS21735	ENOG4105DIV	Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds (By similarity)
DEH18_RS21745	ENOG41088PD	hydrolase
DEH18_RS21780	ENOG4105EC2	ftsk spoIIIe
DEH18_RS21800	ENOG4106F1P	AAA ATPase, central domain protein
DEH18_RS21860	ENOG4108X7A	Terpene synthase metal-binding domain-containing protein
DEH18_RS21865	ENOG4105E8G	Major facilitator Superfamily
DEH18_RS21875	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
DEH18_RS21885	ENOG4105EXU	Membrane
DEH18_RS21950	ENOG4105CIB	oxidoreductase Domain protein
DEH18_RS21955	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
DEH18_RS21960	ENOG4105CNN	ABC, transporter
DEH18_RS21965	ENOG4105C2J	ABC transporter
DEH18_RS21970	ENOG4105DKQ	ROK family
DEH18_RS21975	ENOG4108KPJ	rna polymerase sigma factor
DEH18_RS21980	ENOG4107XEY	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
DEH18_RS21995	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
DEH18_RS22005	ENOG4108373	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
DEH18_RS22010	ENOG4105D65	subunit l
DEH18_RS22015	ENOG4105C8S	subunit m
DEH18_RS22020	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
DEH18_RS22035	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
DEH18_RS22040	ENOG4105DHU	Bile acid
DEH18_RS22050	ENOG4105CV8	reductase
DEH18_RS22055	ENOG410842T	Pterin carbinolamine dehydratase
DEH18_RS22075	ENOG4107T8T	UPF0173 metal-dependent hydrolase
DEH18_RS22110	ENOG41080XP	Cbs domain
DEH18_RS22115	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
DEH18_RS22155	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
DEH18_RS22160	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
DEH18_RS22165	ENOG4108ME1	Peptidase M55 D-aminopeptidase
DEH18_RS22220	ENOG4105RFZ	Methylmalonyl-coA mutase
DEH18_RS22225	ENOG4105CI0	Citrate lyase
DEH18_RS22235	ENOG4105C1G	acyl-Coa dehydrogenase
DEH18_RS22240	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
DEH18_RS22250	ENOG4105BZW	Glycerate kinase
DEH18_RS22255	ENOG4105C94	Transporter
DEH18_RS22265	ENOG4105ECY	inositol monophosphatase
DEH18_RS22270	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
DEH18_RS22280	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
DEH18_RS22285	ENOG4105DF9	Lipoate-protein, ligase
DEH18_RS22310	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
DEH18_RS22315	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
DEH18_RS22325	ENOG4105C1G	acyl-Coa dehydrogenase
DEH18_RS22335	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
DEH18_RS22340	ENOG4105CEY	Amp-dependent synthetase and ligase
DEH18_RS22380	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
DEH18_RS22385	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
DEH18_RS22390	ENOG4108PCN	EamA-like transporter family
DEH18_RS22395	ENOG4108NBA	ATP-dependent carboxylate-amine ligase (By similarity)
DEH18_RS22415	ENOG4105E93	esterase
DEH18_RS22425	ENOG4105BZ1	(ABC) transporter
DEH18_RS22430	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
DEH18_RS22440	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
DEH18_RS22450	ENOG4105DQ5	transport system permease protein
DEH18_RS22455	ENOG4105TVJ	transport system, permease
DEH18_RS22490	ENOG4105CEY	Amp-dependent synthetase and ligase
DEH18_RS22495	ENOG4105WQI	isochorismatase
DEH18_RS22500	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
DEH18_RS22505	ENOG4105E4F	Isochorismate synthase
DEH18_RS22510	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
DEH18_RS22520	ENOG4108JGH	Tetr family transcriptional regulator
DEH18_RS22535	ENOG4105CHJ	isochorismatase hydrolase
DEH18_RS22585	ENOG4105DND	Transcriptional regulator
DEH18_RS22600	ENOG4107RNN	dihydropyrimidinase (EC 3.5.2.2)
DEH18_RS22605	ENOG4105C8Y	Acetylornithine aminotransferase
DEH18_RS22625	ENOG41080V3	Major Facilitator superfamily
DEH18_RS22630	ENOG4105D3W	isochorismatase
DEH18_RS22640	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
DEH18_RS22650	ENOG4105DRP	amino acid AbC transporter
DEH18_RS22655	ENOG4105EAD	ABC transporter
DEH18_RS22660	ENOG4107UBR	Extracellular solute-binding protein family 3
DEH18_RS22665	ENOG4105CDA	abc transporter atp-binding protein
DEH18_RS22690	ENOG4105E8R	UPF0173 metal-dependent hydrolase
DEH18_RS22695	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
DEH18_RS22705	ENOG4105DKQ	ROK family
DEH18_RS22710	ENOG4105C2J	ABC transporter
DEH18_RS22715	ENOG41062B0	ABC transporter, permease
DEH18_RS22725	ENOG4105FDP	GntR family transcriptional regulator
DEH18_RS22730	ENOG4106448	streptomycin biosynthesis protein strI
DEH18_RS22745	ENOG4108UHU	Aldolase
DEH18_RS22760	ENOG4105DHG	Allantoate amidinohydrolase
DEH18_RS22770	ENOG4107HP6	Transcriptional regulator
DEH18_RS22785	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
DEH18_RS22790	ENOG4107R9S	Malate synthase
DEH18_RS22805	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
DEH18_RS22830	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
DEH18_RS22835	ENOG4105DMQ	Methyltransferase
DEH18_RS22850	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
DEH18_RS22860	ENOG4105VT2	5-hydroxyisourate hydrolase
DEH18_RS22880	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
DEH18_RS22915	ENOG4107TFQ	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
DEH18_RS22920	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
DEH18_RS22925	ENOG41060W2	glyoxylate carboligase
DEH18_RS22930	ENOG4105CH6	catalase
DEH18_RS22940	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
DEH18_RS22955	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
DEH18_RS22970	ENOG4105C7N	Xanthine uracil vitamin C permease
DEH18_RS23000	ENOG4105WH1	Two component transcriptional regulator luxr family
DEH18_RS23005	ENOG4105ENE	Histidine kinase
DEH18_RS23025	ENOG4105DRR	Transcriptional regulator, GntR family
DEH18_RS23060	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
DEH18_RS23065	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
DEH18_RS23070	ENOG4107Y2X	deaminase
DEH18_RS23080	ENOG4105CSU	acyl-Coa dehydrogenase
DEH18_RS23100	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
DEH18_RS23105	ENOG4105M6F	mutator MutT protein
DEH18_RS23110	ENOG4105CBG	Sulfatase
DEH18_RS23120	ENOG4106A3M	Cytochrome p-450
DEH18_RS23125	ENOG4105FDF	Could be involved in DNA repair (By similarity)
DEH18_RS23140	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
DEH18_RS23145	ENOG4105ED2	Beta-lactamase
DEH18_RS23180	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
DEH18_RS23190	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
DEH18_RS23195	ENOG4107T1U	Catalyzes the synthesis of activated sulfate (By similarity)
DEH18_RS23215	ENOG4108IY8	ABC, transporter
DEH18_RS23220	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
DEH18_RS23230	ENOG4107NHD	transcriptional regulator
DEH18_RS23240	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
DEH18_RS23275	ENOG4105DND	Transcriptional regulator
DEH18_RS23295	ENOG4105E0X	reductase
DEH18_RS23300	ENOG4105DFU	Cell wall formation (By similarity)
DEH18_RS23350	ENOG4107JTW	chlorite dismutase
DEH18_RS23355	ENOG4105C1Q	protoporphyrinogen oxidase
DEH18_RS23360	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
DEH18_RS23365	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
DEH18_RS23375	ENOG4105WH1	Two component transcriptional regulator luxr family
DEH18_RS23385	ENOG4105CHU	acetyl-coa acetyltransferase
DEH18_RS23390	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
DEH18_RS23405	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
DEH18_RS23425	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
DEH18_RS23430	ENOG4108HWW	ABC transporter
DEH18_RS23435	ENOG4105C2J	ABC transporter
DEH18_RS23440	ENOG4105DFW	ABC transporter
DEH18_RS23445	ENOG4105E2R	ROK family
DEH18_RS23490	ENOG4105CD5	CoA-binding domain protein
DEH18_RS23505	ENOG4108WYP	Transcriptional regulator
DEH18_RS23510	ENOG4107QM5	aconitate hydratase
DEH18_RS23540	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
DEH18_RS23570	ENOG4105CNI	cell division protein FtsW
DEH18_RS23625	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
DEH18_RS23635	ENOG4105E98	transcriptional regulator DeoR family
DEH18_RS23640	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
DEH18_RS23645	ENOG4107VFR	oxidoreductase
DEH18_RS23650	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
DEH18_RS23655	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
DEH18_RS23705	ENOG4105CGU	Enoyl-CoA hydratase
DEH18_RS23735	ENOG4108J5H	Homocysteine s-methyltransferase
DEH18_RS23740	ENOG4105CEU	Arginine dihydrolase
DEH18_RS23745	ENOG4105DBV	ornithine carbamoyltransferase
DEH18_RS23750	ENOG4105CUB	amino acid
DEH18_RS23795	ENOG4108WC5	Alpha Beta Hydrolase Fold protein
DEH18_RS23800	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
DEH18_RS23820	ENOG41068HZ	50S ribosomal protein L32
DEH18_RS23835	ENOG4105W0E	50S ribosomal protein L33
DEH18_RS23845	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
DEH18_RS23855	ENOG4105DG6	mannose-6-phosphate isomerase
DEH18_RS23870	ENOG4105D9P	serine threonine protein kinase
DEH18_RS23950	ENOG4108M21	
DEH18_RS23960	ENOG4105MUZ	Protein of unknown function DUF2620
DEH18_RS23965	ENOG4106M0N	transport system permease protein
DEH18_RS23970	ENOG41080QX	K07048 phosphotriesterase-related protein
DEH18_RS23975	ENOG4106PKC	pyridoxal phosphate binding
DEH18_RS23980	ENOG4108626	Racemase
DEH18_RS23985	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
DEH18_RS24005	ENOG4105IJJ	transcriptional regulator, crp fnr family
DEH18_RS24015	ENOG4106JUT	Streptomycin 3''-adenylyltransferase
DEH18_RS24020	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
DEH18_RS24025	ENOG4108WYP	Transcriptional regulator
DEH18_RS24035	ENOG4105CTU	Proline racemase
DEH18_RS24045	ENOG4107KMQ	bfd domain protein (2fe-2s)-binding domain protein
DEH18_RS24045	ENOG4107KMQ	bfd domain protein (2fe-2s)-binding domain protein
DEH18_RS24050	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
DEH18_RS24060	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
DEH18_RS24065	ENOG4105CSH	Transporter
DEH18_RS24080	ENOG4108KPW	sugar kinase
DEH18_RS24085	ENOG4107R1S	catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine
DEH18_RS24090	ENOG4105ETE	Transcriptional regulator (LacI family
DEH18_RS24145	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
DEH18_RS24155	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
DEH18_RS24175	ENOG4105YVS	arsR family transcriptional regulator
DEH18_RS24185	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
DEH18_RS24195	ENOG4105F8D	glycoside hydrolase family 4
DEH18_RS24200	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
DEH18_RS24215	ENOG4105E2R	ROK family
DEH18_RS24250	ENOG4105JQZ	Methyltransferase
DEH18_RS24265	ENOG4106NZI	LysR family Transcriptional regulator
DEH18_RS24280	ENOG4105CSH	Transporter
DEH18_RS24285	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
DEH18_RS24290	ENOG4105BZU	Histidine kinase
DEH18_RS24300	ENOG4105EDW	glycosyl transferase, family 39
DEH18_RS24300	ENOG4105EDW	glycosyl transferase, family 39
DEH18_RS24325	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
DEH18_RS24365	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
DEH18_RS24370	ENOG4108W5M	transcriptional regulator
DEH18_RS24455	ENOG4105BZU	Histidine kinase
DEH18_RS24465	ENOG4105CVK	Glutamate decarboxylase
DEH18_RS24475	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
DEH18_RS24490	ENOG4108ME1	Peptidase M55 D-aminopeptidase
DEH18_RS24500	ENOG4108JGH	Tetr family transcriptional regulator
DEH18_RS24535	ENOG4105C6Z	Gluconate
DEH18_RS24545	ENOG4108V9W	transcriptional regulatory protein
DEH18_RS24550	ENOG4105C26	Dehydrogenase
DEH18_RS24560	ENOG4105CXY	transporter
DEH18_RS24585	ENOG4108N6D	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
DEH18_RS24620	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
DEH18_RS24625	ENOG4105C26	Dehydrogenase
DEH18_RS24630	ENOG4105DRR	Transcriptional regulator, GntR family
DEH18_RS24660	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
DEH18_RS24665	ENOG4105C0X	amino acid
DEH18_RS24670	ENOG4107VEG	TrkA-N domain protein
DEH18_RS24700	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
DEH18_RS24710	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
DEH18_RS24715	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
DEH18_RS24720	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
DEH18_RS24735	ENOG4107ZFB	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
DEH18_RS24760	ENOG4106F60	Histidine kinase
DEH18_RS24765	ENOG4105F44	Two component transcriptional regulator, winged helix family
DEH18_RS24775	ENOG4107QME	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
DEH18_RS24810	ENOG4107W53	thymidine kinase
DEH18_RS24825	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
DEH18_RS24830	ENOG410849S	phosphocarrier protein (HPr)
DEH18_RS24835	ENOG41061JJ	Peptidase family M23
DEH18_RS24850	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
DEH18_RS24870	ENOG4107QN1	sodium solute
DEH18_RS24880	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
DEH18_RS24890	ENOG4105NDH	peptidase s1 and s6 chymotrypsin hap
DEH18_RS24895	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
DEH18_RS24905	ENOG4105CJ1	ABC, transporter
DEH18_RS24925	ENOG4105C9U	ATP-dependent DNA helicase RecQ
DEH18_RS24940	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
DEH18_RS24950	ENOG4105CVJ	phosphoglycerate mutase
DEH18_RS24960	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
DEH18_RS24965	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
DEH18_RS24970	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
DEH18_RS25000	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
DEH18_RS25010	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
DEH18_RS25015	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
DEH18_RS25025	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
DEH18_RS25045	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
DEH18_RS25055	ENOG4105EB3	Histidine kinase
DEH18_RS25065	ENOG4105CDA	abc transporter atp-binding protein
DEH18_RS25070	ENOG4105CT1	(ABC) transporter
DEH18_RS25075	ENOG4108Q1T	ABC transporter
DEH18_RS25080	ENOG4105DRP	amino acid AbC transporter
DEH18_RS25085	ENOG4107SCK	Monooxygenase
DEH18_RS25095	ENOG4107SNB	ankyrin repeat protein YahD
DEH18_RS25105	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
DEH18_RS25110	ENOG4105C02	permease
DEH18_RS25135	ENOG4106AXJ	AraC family transcriptional regulator
DEH18_RS25140	ENOG4107QRT	dEAD DEAH box helicase
DEH18_RS25145	ENOG4108S0J	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'- phosphates (By similarity)
DEH18_RS25155	ENOG4105WBV	Transcriptional regulator
DEH18_RS25160	ENOG4105CEV	competence damage-inducible protein
DEH18_RS25170	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
DEH18_RS25180	ENOG4107QZI	cell division protein FtsK
DEH18_RS25185	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
DEH18_RS25190	ENOG4105BZU	Histidine kinase
DEH18_RS25225	ENOG4105CN5	Metallo-Beta-Lactamase
DEH18_RS25230	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
DEH18_RS25255	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
DEH18_RS25260	ENOG4105C1V	Peptidase, M16
DEH18_RS25265	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
DEH18_RS25270	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
DEH18_RS25280	ENOG4105EC2	ftsk spoIIIe
DEH18_RS25300	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
DEH18_RS25350	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
DEH18_RS25355	ENOG4107ZPY	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
DEH18_RS25365	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
DEH18_RS25380	ENOG4107Z1I	Required for maturation of 30S ribosomal subunits (By similarity)
DEH18_RS25400	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
DEH18_RS25415	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
DEH18_RS25420	ENOG4105DZP	Membrane-associated zinc metalloprotease
DEH18_RS25425	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
DEH18_RS25440	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
DEH18_RS25450	ENOG4105G9B	Transcriptional regulator
DEH18_RS25475	ENOG4105CJP	fad dependent oxidoreductase
DEH18_RS25480	ENOG4105E0C	molybdate abc transporter
DEH18_RS25485	ENOG4105F38	ABC transporter, permease
DEH18_RS25490	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
DEH18_RS25500	ENOG4105C26	Dehydrogenase
DEH18_RS25510	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
DEH18_RS25515	ENOG4105C26	Dehydrogenase
DEH18_RS25525	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
DEH18_RS25530	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
DEH18_RS25540	ENOG4108UCS	ABC, transporter
DEH18_RS25545	ENOG4108I5D	sulfate abc transporter
DEH18_RS25555	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
DEH18_RS25560	ENOG4105KNE	Phosphatidate cytidylyltransferase
DEH18_RS25565	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
DEH18_RS25570	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
DEH18_RS25575	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
DEH18_RS25580	ENOG4105CE9	30S ribosomal protein S2
DEH18_RS25595	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
DEH18_RS25605	ENOG4105C0P	Mg chelatase subunit ChlI
DEH18_RS25610	ENOG41080R2	UPF0102 protein
DEH18_RS25620	ENOG4105C3F	Signal peptidase i
DEH18_RS25625	ENOG4107QYR	Signal peptidase i
DEH18_RS25630	ENOG4107QYR	Signal peptidase i
DEH18_RS25640	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
DEH18_RS25645	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
DEH18_RS25650	ENOG4107XUM	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
DEH18_RS25655	ENOG41082KU	UPF0109 protein
DEH18_RS25660	ENOG4105K5M	30s ribosomal protein S16
DEH18_RS25670	ENOG4107R1M	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) (By similarity)
DEH18_RS25725	ENOG4108375	Acylphosphatase (EC 3.6.1.7)
DEH18_RS25735	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
DEH18_RS25740	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
DEH18_RS25745	ENOG41084BZ	50S ribosomal protein L32
DEH18_RS25760	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
DEH18_RS25765	ENOG4106H78	methyltransferase
DEH18_RS25775	ENOG4105DP4	dak2 domain fusion protein ylov
DEH18_RS25780	ENOG4105VB9	50S ribosomal protein l28
DEH18_RS25785	ENOG4105DWF	phosphomethylpyrimidine kinase
DEH18_RS25805	ENOG4105CPF	Cell wall formation (By similarity)
DEH18_RS25810	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
DEH18_RS25820	ENOG4105ME0	Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor (By similarity)
DEH18_RS25830	ENOG4105K70	DNA-binding protein
DEH18_RS25840	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
DEH18_RS25845	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
DEH18_RS25850	ENOG41069M3	Transcriptional regulator
DEH18_RS25870	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
DEH18_RS25875	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
DEH18_RS25890	ENOG4105GWZ	Roadblock lc7 family protein
DEH18_RS25910	ENOG4105GWZ	Roadblock lc7 family protein
DEH18_RS25930	ENOG4105D8K	carboxyl transferase
DEH18_RS25935	ENOG4106AM8	polysaccharide lyase family 8
DEH18_RS25945	ENOG4105CQM	Urea amidohydrolase subunit alpha
DEH18_RS25950	ENOG4105DWY	Agmatine deiminase
DEH18_RS25960	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
DEH18_RS25965	ENOG4105DGI	Alkaline phosphatase
DEH18_RS25970	ENOG4105CM2	brancheD-chain amino acid aminotransferase
DEH18_RS25975	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
DEH18_RS25985	ENOG4105C26	Dehydrogenase
DEH18_RS25995	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
DEH18_RS26000	ENOG4105CIR	epoxide hydrolase
DEH18_RS26010	ENOG4108JQ1	Dehydrogenase
DEH18_RS26015	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
DEH18_RS26020	ENOG4108ZP8	Acetolactate synthase small subunit
DEH18_RS26030	ENOG4105BZU	Histidine kinase
DEH18_RS26035	ENOG4108JQ1	Dehydrogenase
DEH18_RS26040	ENOG4105CPC	Aldo Keto reductase
DEH18_RS26065	ENOG4105EYF	MMPL domain protein
DEH18_RS26070	ENOG4105HSS	phospholipase C
DEH18_RS26085	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
DEH18_RS26125	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
DEH18_RS26145	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
DEH18_RS26155	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
DEH18_RS26160	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
DEH18_RS26165	ENOG4105BZU	Histidine kinase
DEH18_RS26170	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
DEH18_RS26180	ENOG4105EMU	Dehydrogenase
DEH18_RS26185	ENOG4105DFF	Rod shape-determining protein mreb
DEH18_RS26200	ENOG4108URH	decarboxylase
DEH18_RS26205	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
DEH18_RS26225	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
DEH18_RS26235	ENOG4105C26	Dehydrogenase
DEH18_RS26240	ENOG4108JQ7	(ABC) transporter
DEH18_RS26255	ENOG4108J59	Extracellular solute-binding protein, family 5
DEH18_RS26260	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
DEH18_RS26285	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
DEH18_RS26290	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
DEH18_RS26295	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
DEH18_RS26300	ENOG4105EJQ	L-serine dehydratase
DEH18_RS26310	ENOG4107SCK	Monooxygenase
DEH18_RS26370	ENOG4105EN6	Membrane
DEH18_RS26385	ENOG4108V06	Glutathione peroxidase
DEH18_RS26410	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
DEH18_RS26425	ENOG4106NZI	LysR family Transcriptional regulator
DEH18_RS26430	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
DEH18_RS26435	ENOG4105CPQ	Dehydrogenase
DEH18_RS26445	ENOG4108RVA	ribokinase
DEH18_RS26450	ENOG4105ETE	Transcriptional regulator (LacI family
DEH18_RS26455	ENOG4105DU0	nucleoside hydrolase
DEH18_RS26490	ENOG4105BZ1	(ABC) transporter
DEH18_RS26510	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
DEH18_RS26520	ENOG41070F3	Catalyzes the ATP-dependent phosphorylation of maltose to maltose 1-phosphate. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, GlgE and GlgB (By similarity)
DEH18_RS26525	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
DEH18_RS26540	ENOG4108MRH	transcriptional regulatory protein
DEH18_RS26545	ENOG4106UDK	Cellulose-binding, family II
DEH18_RS26580	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
DEH18_RS26590	ENOG4107RSM	transcriptional regulator
DEH18_RS26595	ENOG4105F27	Major Facilitator
DEH18_RS26600	ENOG4105D9P	serine threonine protein kinase
DEH18_RS26605	ENOG4105CTQ	phosphohexokinase
DEH18_RS26610	ENOG4105C6K	Malic enzyme
DEH18_RS26615	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
DEH18_RS26670	ENOG4105WX6	Membrane
DEH18_RS26715	ENOG4105ETX	regulatoR
DEH18_RS26730	ENOG4105CHU	acetyl-coa acetyltransferase
DEH18_RS26785	ENOG4105CYV	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures (By similarity)
DEH18_RS26800	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
DEH18_RS26805	ENOG410630P	Transcriptional regulator
DEH18_RS26845	ENOG4105BZU	Histidine kinase
DEH18_RS26850	ENOG4105WH1	Two component transcriptional regulator luxr family
DEH18_RS26875	ENOG410825K	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
DEH18_RS26880	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
DEH18_RS26885	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
DEH18_RS26890	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
DEH18_RS26895	ENOG4108T62	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
DEH18_RS26900	ENOG4107Z0K	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
DEH18_RS26905	ENOG4105ZA1	atp synthase
DEH18_RS26915	ENOG4105Z3P	ATP synthase
DEH18_RS26925	ENOG4107ZF2	Phosphatase
DEH18_RS26935	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
DEH18_RS26940	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
DEH18_RS26945	ENOG4105VFB	Binds the 23S rRNA (By similarity)
DEH18_RS26960	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
DEH18_RS26965	ENOG4107R5I	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
DEH18_RS26975	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
DEH18_RS26980	ENOG4105C75	arginyL-tRNA synthetase
DEH18_RS26980	ENOG4105C75	arginyL-tRNA synthetase
DEH18_RS26995	ENOG4108ZJ4	polysaccharide deacetylase
DEH18_RS27050	ENOG4108Z4X	TRANSCRIPTIONal
DEH18_RS27060	ENOG4107QPV	Serine Threonine protein kinase
DEH18_RS27065	ENOG4105K4H	Nlp p60 protein
DEH18_RS27110	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
DEH18_RS27120	ENOG4108PYU	two-component system response regulator
DEH18_RS27125	ENOG4105EB3	Histidine kinase
DEH18_RS27130	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
DEH18_RS27155	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
DEH18_RS27170	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
DEH18_RS27220	ENOG4108ZGX	Histidine kinase
DEH18_RS27240	ENOG4108RZE	Tetr family transcriptional regulator
DEH18_RS27255	ENOG4105CB2	alcohol dehydrogenase
DEH18_RS27275	ENOG4108HW4	amino acid AbC transporter
DEH18_RS27285	ENOG4105C6K	Malic enzyme
DEH18_RS27290	ENOG41090JN	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
DEH18_RS27305	ENOG4108VEQ	Superoxide dismutase
DEH18_RS27310	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
DEH18_RS27320	ENOG4106NZI	LysR family Transcriptional regulator
DEH18_RS27330	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
DEH18_RS27350	ENOG4105K6H	D-cysteine desulfhydrase
DEH18_RS27370	ENOG4105CBD	Diacylglycerol kinase
DEH18_RS27385	ENOG4105FB2	class II Aldolase
DEH18_RS27390	ENOG4105DKT	Transcriptional regulator
DEH18_RS27395	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
DEH18_RS27400	ENOG4105D17	glycoside hydrolase, family 3 domain protein
DEH18_RS27420	ENOG4105FDP	GntR family transcriptional regulator
DEH18_RS27425	ENOG4105D22	carbon starvation protein
DEH18_RS27450	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
DEH18_RS27455	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
DEH18_RS27460	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
DEH18_RS27475	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
DEH18_RS27480	ENOG4105WMN	AntiSigma factor
DEH18_RS27485	ENOG4105EMN	RNA polymerase sigma factor
DEH18_RS27495	ENOG4108RAV	Conserved protein
DEH18_RS27505	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
DEH18_RS27510	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
DEH18_RS27515	ENOG4105KPY	Small multidrug resistance protein
DEH18_RS27525	ENOG4107TK4	histidinol-phosphate phosphatase
DEH18_RS27580	ENOG4105DJZ	UPF0182 protein
DEH18_RS27590	ENOG41063PX	domain protein
DEH18_RS27640	ENOG4105WBQ	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
DEH18_RS27665	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
DEH18_RS27690	ENOG4106JDR	secreted
DEH18_RS27755	ENOG4105C1J	atp-dependent rna helicase
DEH18_RS27760	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
DEH18_RS27765	ENOG41081FY	multiple antibiotic resistance (MarC)-related
DEH18_RS27770	ENOG4105DB7	PHP domain protein
DEH18_RS27780	ENOG4105DXB	Major Facilitator superfamily
DEH18_RS27790	ENOG4105D7N	magnesium and cobalt transport protein CorA
DEH18_RS27805	ENOG4105CJW	magnesium transporter
DEH18_RS27825	ENOG410630M	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
DEH18_RS27830	ENOG4105C0H	protease
DEH18_RS27840	ENOG4105DU6	RNA polymerase
DEH18_RS27845	ENOG4107ZBN	O-methyltransferase
DEH18_RS27855	ENOG4105CGU	Enoyl-CoA hydratase
DEH18_RS27860	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
DEH18_RS27870	ENOG4105EEI	dihydropteroate synthase
DEH18_RS27875	ENOG4108URH	decarboxylase
DEH18_RS27880	ENOG4107R4C	succinyl-diaminopimelate desuccinylase
DEH18_RS27900	ENOG4108Z4U	Ferredoxin
DEH18_RS27915	ENOG4108S01	response regulator
DEH18_RS27920	ENOG4105BZU	Histidine kinase
DEH18_RS27930	ENOG4108M15	ABC transporter
DEH18_RS27945	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
DEH18_RS27960	ENOG4108JQ7	(ABC) transporter
DEH18_RS27965	ENOG4105C3U	ABC transporter
DEH18_RS27980	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
DEH18_RS27990	ENOG4108JQ7	(ABC) transporter
DEH18_RS28000	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
DEH18_RS28005	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
DEH18_RS28015	ENOG4108JQ7	(ABC) transporter
DEH18_RS28020	ENOG4105C3U	ABC transporter
DEH18_RS28025	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
DEH18_RS28030	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
DEH18_RS28040	ENOG4105CI3	gtp-binding protein typa
DEH18_RS28070	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
DEH18_RS28095	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
DEH18_RS28105	ENOG4105BZU	Histidine kinase
DEH18_RS28125	ENOG4108NMT	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon (By similarity)
DEH18_RS28130	ENOG4105WH1	Two component transcriptional regulator luxr family
DEH18_RS28140	ENOG4108MJI	response regulator
DEH18_RS28170	ENOG4105CH2	amidohydrolase
DEH18_RS28185	ENOG4105C3G	gtp-binding protein
DEH18_RS28195	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
DEH18_RS28205	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
DEH18_RS28210	ENOG4105YX8	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
DEH18_RS28215	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
DEH18_RS28240	ENOG4107GFK	fumarate
DEH18_RS28255	ENOG4105C9Q	fumarate hydratase class II
DEH18_RS28265	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
DEH18_RS28275	ENOG4108X7C	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
DEH18_RS28280	ENOG4105D3R	alkyl hydroperoxide reductase
DEH18_RS28305	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
DEH18_RS28315	ENOG4105CH6	catalase
DEH18_RS28335	ENOG4108IAB	Phoh family
DEH18_RS28340	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
DEH18_RS28345	ENOG4105CPC	Aldo Keto reductase
DEH18_RS28365	ENOG41082BM	Transcriptional regulator, arsr family
DEH18_RS28385	ENOG41090EK	ompa motb domain protein
DEH18_RS28405	ENOG4107QNK	)-transporter
DEH18_RS28410	ENOG4105FDP	GntR family transcriptional regulator
DEH18_RS28415	ENOG4105DKQ	ROK family
DEH18_RS28420	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
DEH18_RS28500	ENOG4105C6Z	Gluconate
DEH18_RS28540	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
DEH18_RS28550	ENOG4105CHM	Aminotransferase
DEH18_RS28565	ENOG4105C7Z	Conserved Protein
DEH18_RS28625	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
DEH18_RS28635	ENOG4105CEY	Amp-dependent synthetase and ligase
DEH18_RS28645	ENOG4108222	arsenate reductase
DEH18_RS28660	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
DEH18_RS28705	ENOG4105C7B	Threonine dehydratase
DEH18_RS28720	ENOG4107YD5	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
DEH18_RS28735	ENOG4105T1M	mycothiol conjugate amidase mca
DEH18_RS28745	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
DEH18_RS28780	ENOG4105C84	Histidine ammonia-lyase
DEH18_RS28785	ENOG4105KDM	Diguanylate cyclase with gaf sensor
DEH18_RS28790	ENOG4105E39	Enoyl-CoA hydratase
DEH18_RS28795	ENOG4108QER	Adenylate cyclase
DEH18_RS28800	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
DEH18_RS28805	ENOG4105D8K	carboxyl transferase
DEH18_RS28815	ENOG4107WR6	Maf-like protein
DEH18_RS28825	ENOG4108JIK	carboxylase
DEH18_RS28850	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
DEH18_RS28895	ENOG4105C26	Dehydrogenase
DEH18_RS28900	ENOG4107YPT	transcriptional regulator
DEH18_RS28935	ENOG4105CAT	Cytidine monophosphate kinase
DEH18_RS28940	ENOG4105NAF	rna polymerase sigma factor
DEH18_RS28945	ENOG4108KXV	response regulator
DEH18_RS28950	ENOG41065SU	Two-component system sensor kinase
DEH18_RS28975	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
DEH18_RS28985	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
DEH18_RS28990	ENOG4107RSM	transcriptional regulator
DEH18_RS28995	ENOG4105D94	Major Facilitator Superfamily
DEH18_RS29015	ENOG4105UIB	(ABC) transporter
DEH18_RS29030	ENOG4107RM1	amidohydrolase
DEH18_RS29065	ENOG4105ZXK	Dehydrogenase
DEH18_RS29075	ENOG4107SCK	Monooxygenase
DEH18_RS29100	ENOG4105GFR	rna polymerase sigma factor
DEH18_RS29105	ENOG4105E2D	ec 3.2.1.52
DEH18_RS29155	ENOG4107RN3	metallophosphoesterase
DEH18_RS29170	ENOG4107H3J	ribonuclease
DEH18_RS29180	ENOG4105C31	Tryptophanyl-tRNA synthetase
DEH18_RS29185	ENOG4105C8Y	Acetylornithine aminotransferase
DEH18_RS29190	ENOG4105D9U	N-acetyltransferase
DEH18_RS29200	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
DEH18_RS29240	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
DEH18_RS29245	ENOG4105C1G	acyl-Coa dehydrogenase
DEH18_RS29250	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
DEH18_RS29255	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
DEH18_RS29260	ENOG4107RNB	anthranilate phosphoribosyltransferase
DEH18_RS29285	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
DEH18_RS29315	ENOG4105CHR	reductase
DEH18_RS29320	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
DEH18_RS29335	ENOG4105F95	Monooxygenase
DEH18_RS29365	ENOG4105ECR	NmrA family
DEH18_RS29420	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
DEH18_RS29485	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
DEH18_RS29500	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
DEH18_RS29510	ENOG4105CZS	beta-ketoacyl synthase
DEH18_RS29530	ENOG41064MX	Tetr family transcriptional regulator
DEH18_RS29545	ENOG4105D8K	carboxyl transferase
DEH18_RS29560	ENOG41064MX	Tetr family transcriptional regulator
DEH18_RS29570	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
DEH18_RS29575	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
DEH18_RS29585	ENOG4105H3G	oxidoreductase
DEH18_RS29590	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
DEH18_RS29595	ENOG4105CHR	reductase
DEH18_RS29600	ENOG41086VD	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
DEH18_RS29615	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
DEH18_RS29620	ENOG4108XG4	DNA-binding transcriptional regulator
DEH18_RS29630	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
DEH18_RS29645	ENOG4105CJP	fad dependent oxidoreductase
DEH18_RS29660	ENOG4105C8Y	Acetylornithine aminotransferase
DEH18_RS29680	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
DEH18_RS29740	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
DEH18_RS29760	ENOG4108HQS	Glycine betaine
DEH18_RS29765	ENOG4108IJ7	Glycine betaine
DEH18_RS29775	ENOG4105C26	Dehydrogenase
DEH18_RS29785	ENOG4105C22	threonyL-tRNA synthetase
DEH18_RS29810	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
DEH18_RS29825	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
DEH18_RS29845	ENOG4108V5V	Serine Threonine protein kinase
DEH18_RS29850	ENOG4105DC1	bifunctional purine biosynthesis protein purh
DEH18_RS29875	ENOG4105WH1	Two component transcriptional regulator luxr family
DEH18_RS29880	ENOG4108ZGX	Histidine kinase
DEH18_RS29890	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
DEH18_RS29895	ENOG4105DEG	Vwa containing coxe family protein
DEH18_RS29905	ENOG4105KKX	ATPase associated with various cellular activities aaa_5
DEH18_RS29925	ENOG41061JJ	Peptidase family M23
DEH18_RS29955	ENOG4108DNI	pyridine nucleotide-disulfide oxidoreductase
DEH18_RS29980	ENOG4108IND	Tetr family transcriptional regulator
DEH18_RS29985	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
DEH18_RS30000	ENOG4105F6J	Alpha beta hydrolase fold
DEH18_RS30025	ENOG4105WH1	Two component transcriptional regulator luxr family
DEH18_RS30065	ENOG41082W1	Cupin 2, conserved barrel domain protein
DEH18_RS30070	ENOG4105ECQ	AraC Family Transcriptional Regulator
DEH18_RS30085	ENOG4105ETS	cytosine purines uracil thiamine allantoin
DEH18_RS30115	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
DEH18_RS30120	ENOG4106D2I	Chorismate mutase
DEH18_RS30135	ENOG4108SGK	Tetr family transcriptional regulator
DEH18_RS30155	ENOG4108DT4	serine threonine protein kinase
DEH18_RS30160	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
DEH18_RS30165	ENOG4107QQG	Dehydrogenase
DEH18_RS30170	ENOG4107QVP	Dehydrogenase
DEH18_RS30180	ENOG4108MMM	RNA Polymerase
DEH18_RS30185	ENOG4105WH1	Two component transcriptional regulator luxr family
DEH18_RS30190	ENOG4105KIU	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
DEH18_RS30195	ENOG4105DND	Transcriptional regulator
DEH18_RS30205	ENOG4105EMU	Dehydrogenase
DEH18_RS30220	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
DEH18_RS30265	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
DEH18_RS30295	ENOG4108097	ATP-binding protein
DEH18_RS30305	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
DEH18_RS30325	ENOG41082KK	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
DEH18_RS30330	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
DEH18_RS30340	ENOG4105CS9	pantothenic acid kinase
DEH18_RS30345	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
DEH18_RS30350	ENOG4108UJD	30S ribosomal protein S9
DEH18_RS30355	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
DEH18_RS30370	ENOG4105DZ6	Band 7 protein
DEH18_RS30375	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
DEH18_RS30380	ENOG4108ZT0	50S ribosomal protein l17
DEH18_RS30385	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
DEH18_RS30390	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
DEH18_RS30395	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
DEH18_RS30400	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DEH18_RS30410	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
DEH18_RS30420	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
DEH18_RS30430	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
DEH18_RS30435	ENOG410849U	50S ribosomal protein L30
DEH18_RS30440	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
DEH18_RS30445	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
DEH18_RS30450	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
DEH18_RS30455	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
DEH18_RS30460	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
DEH18_RS30465	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DEH18_RS30470	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
DEH18_RS30475	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
DEH18_RS30480	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
DEH18_RS30485	ENOG41082SA	50s ribosomal protein l29
DEH18_RS30490	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
DEH18_RS30495	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
DEH18_RS30500	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
DEH18_RS30505	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
DEH18_RS30510	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DEH18_RS30515	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
DEH18_RS30520	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
DEH18_RS30525	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
DEH18_RS30530	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
DEH18_RS30535	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
DEH18_RS30540	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
DEH18_RS30545	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
DEH18_RS30550	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
DEH18_RS30555	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
DEH18_RS30560	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
DEH18_RS30565	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
DEH18_RS30570	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
DEH18_RS30575	ENOG4108VZM	50s ribosomal protein L10
DEH18_RS30585	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
DEH18_RS30590	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
DEH18_RS30595	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
DEH18_RS30630	ENOG4107R4N	Cell wall formation (By similarity)
DEH18_RS30640	ENOG410900P	UPF0336 protein
DEH18_RS30645	ENOG4105WDJ	50S ribosomal protein L33
DEH18_RS30670	ENOG4105WH1	Two component transcriptional regulator luxr family
DEH18_RS30675	ENOG4105BZU	Histidine kinase
DEH18_RS30695	ENOG4107414	GntR family transcriptional regulator
DEH18_RS30785	ENOG4107ZVI	PhiRv2 prophage protein
DEH18_RS30805	ENOG4108VPT	UPF0234 protein
DEH18_RS30810	ENOG410901E	Membrane
DEH18_RS30815	ENOG4105D0M	Protease HtpX homolog
DEH18_RS30825	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
DEH18_RS30830	ENOG4105C8S	subunit m
DEH18_RS30835	ENOG4105D65	subunit l
DEH18_RS30840	ENOG41082X4	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
DEH18_RS30845	ENOG4107YX3	NADH dehydrogenase subunit j
DEH18_RS30850	ENOG4108M11	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
DEH18_RS30855	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
DEH18_RS30860	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DEH18_RS30865	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
DEH18_RS30870	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DEH18_RS30885	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
DEH18_RS30890	ENOG4105DQU	oxidoreductase, subunit beta
DEH18_RS30910	ENOG4105CNA	YD repeat protein
DEH18_RS30940	ENOG4105DUX	Transporter
DEH18_RS30965	ENOG4105ERH	Fumarylacetoacetate hydrolase
DEH18_RS30970	ENOG4105C9U	ATP-dependent DNA helicase RecQ
DEH18_RS30975	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
DEH18_RS31000	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
DEH18_RS31010	ENOG4105D65	subunit l
DEH18_RS31015	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
DEH18_RS31020	ENOG41087XN	oxidoreductase
DEH18_RS31025	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
DEH18_RS31030	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
DEH18_RS31035	ENOG4108IEH	NADH dehydrogenase subunit g
DEH18_RS31040	ENOG4107QIZ	NADH dehydrogenase
DEH18_RS31050	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
DEH18_RS31055	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DEH18_RS31060	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
DEH18_RS31085	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
DEH18_RS31090	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
DEH18_RS31100	ENOG4105EV6	Pfam:DUF178
DEH18_RS31105	ENOG4105VEQ	Cold shock protein
DEH18_RS31120	ENOG4107YVI	ribose 5-phosphate isomerase
DEH18_RS31125	ENOG4105CMT	Dihydroxyacetone kinase
DEH18_RS31130	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
DEH18_RS31140	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
DEH18_RS31145	ENOG4105E98	transcriptional regulator DeoR family
DEH18_RS31175	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
DEH18_RS31180	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
DEH18_RS31205	ENOG4105DE9	3-keto-5-aminohexanoate cleavage enzyme
DEH18_RS31210	ENOG4105F35	Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity)
DEH18_RS31220	ENOG4105E2B	Taurine dioxygenase
DEH18_RS31235	ENOG4105D9U	N-acetyltransferase
DEH18_RS31255	ENOG4108IG5	Transcriptional regulator
DEH18_RS31270	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
DEH18_RS31275	ENOG4105DVY	radical SAM domain protein
DEH18_RS31285	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
DEH18_RS31300	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
DEH18_RS31305	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
DEH18_RS31340	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
DEH18_RS31350	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DEH18_RS31355	ENOG4108RH7	phosphoglycerate mutase
DEH18_RS31360	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
DEH18_RS31375	ENOG4105C94	Transporter
DEH18_RS31390	ENOG4105KK4	UPF0060 membrane protein
DEH18_RS31405	ENOG4105DK7	lysyl-tRNA synthetase
DEH18_RS31410	ENOG4105C75	arginyL-tRNA synthetase
DEH18_RS31415	ENOG4105D52	delta-aminolevulinic acid dehydratase
DEH18_RS31420	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
DEH18_RS31425	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
DEH18_RS31430	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
DEH18_RS31435	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
DEH18_RS31445	ENOG4108RXW	HAD-superfamily subfamily IB hydrolase
DEH18_RS31480	ENOG4105DGU	Histone deacetylase
DEH18_RS31500	ENOG41083CW	dedA protein
DEH18_RS31505	ENOG4105II7	pyrroline-5-carboxylate reductase
DEH18_RS31515	ENOG4105CJ1	ABC, transporter
DEH18_RS31520	ENOG4105CHH	sulfate transporter
DEH18_RS31525	ENOG4105EYF	MMPL domain protein
DEH18_RS31545	ENOG4105C01	Dihydroxy-acid dehydratase
DEH18_RS31550	ENOG4105EY0	Xylose isomerase domain protein TIM barrel
DEH18_RS31555	ENOG4107R33	ppx gppa phosphatase
DEH18_RS31575	ENOG4105E59	Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity)
DEH18_RS31585	ENOG4105CEN	a g-specific adenine glycosylase
DEH18_RS31595	ENOG4108IG5	Transcriptional regulator
DEH18_RS31600	ENOG4105DR5	peptidase
DEH18_RS31615	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
DEH18_RS31640	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
DEH18_RS31650	ENOG4108IYU	L-aspartate oxidase
DEH18_RS31655	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
DEH18_RS31670	ENOG4105WH1	Two component transcriptional regulator luxr family
DEH18_RS31685	ENOG4107QN2	dihydrolipoyl dehydrogenase
DEH18_RS31690	ENOG4108IJ8	ABC transporter
DEH18_RS31695	ENOG4105E90	ABC transporter
DEH18_RS31700	ENOG4105E90	ABC transporter
DEH18_RS31715	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
DEH18_RS31730	ENOG4105EEI	dihydropteroate synthase
DEH18_RS31745	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DEH18_RS31755	ENOG4105EUJ	GTP cyclohydrolase i
DEH18_RS31765	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
DEH18_RS31770	ENOG4107RD1	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
DEH18_RS31785	ENOG4105F0N	pyrophosphate phospho-hydrolase
DEH18_RS31795	ENOG4107TXC	Transcriptional regulator
DEH18_RS31810	ENOG4105C26	Dehydrogenase
DEH18_RS31830	ENOG4105WH1	Two component transcriptional regulator luxr family
DEH18_RS31835	ENOG4105BZU	Histidine kinase
DEH18_RS31845	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
DEH18_RS31850	ENOG4105BZ1	(ABC) transporter
DEH18_RS31875	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
DEH18_RS31895	ENOG41067TZ	transcriptional regulator, MarR family
DEH18_RS31910	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
DEH18_RS31930	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
DEH18_RS31935	ENOG41062D9	Histidine kinase
DEH18_RS31940	ENOG4105ETX	regulatoR
DEH18_RS31945	ENOG4105C0H	protease
DEH18_RS31950	ENOG4105ETE	Transcriptional regulator (LacI family
DEH18_RS31955	ENOG4107NHD	transcriptional regulator
DEH18_RS31990	ENOG4105KHC	sulfurtransferase
DEH18_RS31995	ENOG4105PKJ	carbohydrate binding
DEH18_RS32010	ENOG4108X6U	May play a role in the intracellular transport of hydrophobic ligands
DEH18_RS32020	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
DEH18_RS32025	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
DEH18_RS32040	ENOG4105HHS	UPF0256 protein
DEH18_RS32045	ENOG4105JXB	ankyrin repeat-containing protein
DEH18_RS32055	ENOG4105F9V	Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid
DEH18_RS32065	ENOG4108JGH	Tetr family transcriptional regulator
DEH18_RS32090	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
DEH18_RS32105	ENOG4105KVH	Transcriptional regulator
DEH18_RS32155	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
DEH18_RS32160	ENOG4105CJ3	phosphate transporter
DEH18_RS32170	ENOG4105VPX	protein, conserved in bacteria
DEH18_RS32190	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
DEH18_RS32195	ENOG4105E4C	Lytic transglycosylase catalytic
DEH18_RS32330	ENOG4105D5U	fad dependent oxidoreductase
DEH18_RS32335	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
DEH18_RS32355	ENOG410905P	Pyridoxamine 5-phosphate
DEH18_RS32360	ENOG4105CPC	Aldo Keto reductase
DEH18_RS32365	ENOG4105E4C	Lytic transglycosylase catalytic
DEH18_RS32385	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
DEH18_RS32395	ENOG4105JZI	cytochrome P450
DEH18_RS32440	ENOG4107S9F	NmrA family
DEH18_RS32445	ENOG4107R13	MMPL domain protein
DEH18_RS32455	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
DEH18_RS32460	ENOG41082KT	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
DEH18_RS32475	ENOG4107MM9	BNR Asp-box repeat-containing protein
DEH18_RS32485	ENOG4106NZI	LysR family Transcriptional regulator
DEH18_RS32490	ENOG4105IIU	Aminopeptidase
DEH18_RS32510	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
DEH18_RS32515	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
DEH18_RS32545	ENOG4107QRS	glycosyltransferase group 2 family protein
DEH18_RS32550	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
DEH18_RS32565	ENOG4105C8Y	Acetylornithine aminotransferase
DEH18_RS32570	ENOG4105C0A	alcohol dehydrogenase
DEH18_RS32585	ENOG4105CIG	ABC transporter
DEH18_RS32600	ENOG4105CJA	serine threonine protein kinase
DEH18_RS32610	ENOG4105WH1	Two component transcriptional regulator luxr family
DEH18_RS32615	ENOG4108SHN	Glycosyl transferase, family 2
DEH18_RS32620	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
DEH18_RS32635	ENOG4105EQK	-acetyltransferase
DEH18_RS32665	ENOG4105C1J	atp-dependent rna helicase
DEH18_RS32705	ENOG4105DND	Transcriptional regulator
DEH18_RS32710	ENOG4108QIU	Dehydrogenase
DEH18_RS32730	ENOG4107QIV	Cytochrome c biogenesis protein
DEH18_RS32735	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
DEH18_RS32750	ENOG4105CQ7	ATP-dependent helicase
DEH18_RS32785	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
DEH18_RS32865	ENOG4107YH6	single-stranded DNA-binding protein
DEH18_RS32995	ENOG41068JE	domain protein
DEH18_RS33060	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
DEH18_RS33065	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
DEH18_RS33070	ENOG410839H	phosphoribosylformylglycinamidine synthase
DEH18_RS33105	ENOG4105WH1	Two component transcriptional regulator luxr family
DEH18_RS33120	ENOG4105C8V	SAICAR synthetase
DEH18_RS33125	ENOG4105K4I	Scp-like extracellular
DEH18_RS33140	ENOG4105C12	Phosphoribosylglycinamide synthetase
DEH18_RS33165	ENOG4108WYP	Transcriptional regulator
DEH18_RS33170	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
DEH18_RS33190	ENOG4105N14	lysine exporter protein LysE YggA
DEH18_RS33195	ENOG4108ZRZ	Transcriptional regulator (AsnC family)
DEH18_RS33230	ENOG4105DIM	ABC transporter
DEH18_RS33235	ENOG4105CIG	ABC transporter
DEH18_RS33265	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
DEH18_RS33305	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
DEH18_RS33315	ENOG4105C87	Aminotransferase class I and II
DEH18_RS33320	ENOG4105CI1	PTS System
DEH18_RS33325	ENOG4107RCW	fructose-bisphosphate aldolase
DEH18_RS33330	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
DEH18_RS33370	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
DEH18_RS33380	ENOG4105KNI	merR family transcriptional Regulator
DEH18_RS33385	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
DEH18_RS33390	ENOG4108093	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DEH18_RS33395	ENOG4105CFG	Acts as a chaperone (By similarity)
DEH18_RS33400	ENOG4105DF6	Fe-S oxidoreductase
DEH18_RS33420	ENOG4108VQR	secreted hydrolase
DEH18_RS33435	ENOG4105DHP	deoxycytidine triphosphate deaminase
DEH18_RS33465	ENOG4105NAF	rna polymerase sigma factor
DEH18_RS33475	ENOG4105EUB	pirin domain protein
DEH18_RS33495	ENOG4108IUX	(ABC) transporter
DEH18_RS33500	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
DEH18_RS33515	ENOG4105DJ2	Major Facilitator Superfamily
DEH18_RS33535	ENOG4105DA5	(ABC) transporter
DEH18_RS33555	ENOG4107SWG	transcriptional regulator MERR family
DEH18_RS33580	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
DEH18_RS33625	ENOG4108NMT	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon (By similarity)
DEH18_RS33630	ENOG4105D7N	magnesium and cobalt transport protein CorA
DEH18_RS33635	ENOG4105CEP	NADH dehydrogenase
DEH18_RS33655	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
DEH18_RS33675	ENOG4105C57	major facilitator superfamily
DEH18_RS33680	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
DEH18_RS33695	ENOG4105C9M	aspartyl-trna synthetase
DEH18_RS33710	ENOG4105CSU	acyl-Coa dehydrogenase
DEH18_RS33715	ENOG4105DFM	M18 family aminopeptidase
DEH18_RS33740	ENOG4105C7W	Xanthine dehydrogenase
DEH18_RS33745	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
DEH18_RS33750	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
DEH18_RS33760	ENOG4105C26	Dehydrogenase
DEH18_RS33785	ENOG4105D0M	Protease HtpX homolog
DEH18_RS33790	ENOG4108KP7	hydrolase
DEH18_RS33795	ENOG4108JJ9	ABC, transporter
DEH18_RS33800	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
DEH18_RS33805	ENOG4105C4M	(Ubiquinol oxidase) subunit I
DEH18_RS33810	ENOG4105CIH	Imidazole acetol-phosphate transaminase
DEH18_RS33815	ENOG4107P2S	Transcriptional regulator
DEH18_RS33830	ENOG4105C28	cystathionine
DEH18_RS33840	ENOG4105KJF	protein tyrosine phosphatase
DEH18_RS33845	ENOG41082T9	Membrane
DEH18_RS33850	ENOG4106048	Cupin 2, conserved barrel domain protein
DEH18_RS33865	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
DEH18_RS33920	ENOG4107TXC	Transcriptional regulator
DEH18_RS33935	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
DEH18_RS33945	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
DEH18_RS33950	ENOG4105CDU	Replicative dna helicase
DEH18_RS33955	ENOG4107QI1	Mate efflux family protein
DEH18_RS33960	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
DEH18_RS33965	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
DEH18_RS33970	ENOG4107YH6	single-stranded DNA-binding protein
DEH18_RS33975	ENOG410829C	Binds together with S18 to 16S ribosomal RNA (By similarity)
DEH18_RS34005	ENOG4105BZ4	penicillin-binding protein
DEH18_RS34035	ENOG4107QPV	Serine Threonine protein kinase