locus-tag	class	description
FNV59_RS00020	COG2815	serine threonine protein kinase
FNV59_RS00020	COG0515	serine threonine protein kinase
FNV59_RS00150	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FNV59_RS00235	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FNV59_RS00245	COG1309	transcriptional regulator
FNV59_RS00365	COG0069	glutamate synthase activity
FNV59_RS00370	COG3328	transposase activity
FNV59_RS00375	COG3328	transposase activity
FNV59_RS00465	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS00470	COG2353	YceI-like domain
FNV59_RS00480	COG1116	anion transmembrane transporter activity
FNV59_RS00490	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNV59_RS00525	COG3619	membrane
FNV59_RS00530	COG1335	isochorismatase
FNV59_RS00555	COG1131	(ABC) transporter
FNV59_RS00580	COG1609	Transcriptional regulator
FNV59_RS00600	COG0508	dehydrogenase complex catalyzes the overall conversion of
FNV59_RS00605	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FNV59_RS00615	COG2188	Transcriptional regulator
FNV59_RS00620	COG1609	Transcriptional regulator
FNV59_RS00630	COG1609	Transcriptional regulator
FNV59_RS00640	COG2084	Dehydrogenase
FNV59_RS00645	COG0006	proline dipeptidase activity
FNV59_RS00660	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FNV59_RS00670	COG0183	Belongs to the thiolase family
FNV59_RS00675	COG0583	DNA-binding transcription factor activity
FNV59_RS00690	COG1454	alcohol dehydrogenase
FNV59_RS00695	COG1960	acyl-CoA dehydrogenase activity
FNV59_RS00740	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FNV59_RS00830	COG2801	Transposase and inactivated derivatives
FNV59_RS00850	COG2207	Transcriptional regulator
FNV59_RS00915	COG4977	sequence-specific DNA binding
FNV59_RS01005	COG3321	synthase
FNV59_RS01005	COG0604	alcohol dehydrogenase
FNV59_RS01100	COG0248	Ppx GppA phosphatase
FNV59_RS01170	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FNV59_RS01205	COG4585	Histidine kinase
FNV59_RS01220	COG3387	PFAM Glycoside hydrolase 15-related
FNV59_RS01315	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FNV59_RS01360	COG3547	Transposase (IS116 IS110 IS902 family)
FNV59_RS01400	COG3619	membrane
FNV59_RS01410	COG1335	isochorismatase
FNV59_RS01510	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FNV59_RS01520	COG0477	Major facilitator Superfamily
FNV59_RS01545	COG1022	Amp-dependent synthetase and ligase
FNV59_RS01560	COG0667	Aldo Keto reductase
FNV59_RS01570	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FNV59_RS01575	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FNV59_RS01580	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FNV59_RS01585	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FNV59_RS01590	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FNV59_RS01595	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FNV59_RS01600	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS01605	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FNV59_RS01610	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FNV59_RS01635	COG2197	response regulator
FNV59_RS01640	COG0318	PFAM AMP-dependent synthetase and ligase
FNV59_RS01660	COG4221	oxidoreductase activity
FNV59_RS01660	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FNV59_RS01660	COG3321	synthase
FNV59_RS01660	COG0300	oxidoreductase activity
FNV59_RS01680	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FNV59_RS01810	COG1278	Cold shock
FNV59_RS01860	COG0494	nUDIX hydrolase
FNV59_RS01940	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FNV59_RS01945	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FNV59_RS01960	COG2197	response regulator
FNV59_RS01990	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FNV59_RS01995	COG0596	Alpha beta hydrolase
FNV59_RS02050	COG0596	Alpha beta hydrolase
FNV59_RS02105	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FNV59_RS02245	COG3547	Transposase (IS116 IS110 IS902 family)
FNV59_RS02320	COG1959	2 iron, 2 sulfur cluster binding
FNV59_RS02365	COG0477	Major facilitator Superfamily
FNV59_RS02495	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FNV59_RS02510	COG1733	regulation of RNA biosynthetic process
FNV59_RS02515	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FNV59_RS02515	COG4221	oxidoreductase activity
FNV59_RS02515	COG0604	alcohol dehydrogenase
FNV59_RS02515	COG3321	synthase
FNV59_RS02535	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FNV59_RS02620	COG0659	secondary active sulfate transmembrane transporter activity
FNV59_RS02630	COG2824	Alkylphosphonate utilization operon protein PhnA
FNV59_RS02690	COG1136	(ABC) transporter
FNV59_RS02725	COG0456	acetyltransferase
FNV59_RS02755	COG0702	epimerase
FNV59_RS02800	COG2197	response regulator
FNV59_RS02830	COG0114	fumarate hydratase activity
FNV59_RS02835	COG0281	malic enzyme
FNV59_RS02840	COG3842	ATPase activity
FNV59_RS02845	COG1178	ABC-type Fe3 transport system permease component
FNV59_RS02855	COG2409	Drug exporters of the RND superfamily
FNV59_RS02865	COG0745	RESPONSE REGULATOR receiver
FNV59_RS02870	COG2205	protein histidine kinase activity
FNV59_RS02935	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS02950	COG1073	alpha beta
FNV59_RS02960	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FNV59_RS02980	COG0671	phosphoesterase, PA-phosphatase related
FNV59_RS02995	COG2814	Major facilitator Superfamily
FNV59_RS03015	COG0726	polysaccharide deacetylase
FNV59_RS03020	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FNV59_RS03030	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FNV59_RS03035	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FNV59_RS03075	COG2267	carboxylic ester hydrolase activity
FNV59_RS03140	COG4585	Histidine kinase
FNV59_RS03145	COG2197	response regulator
FNV59_RS03165	COG1278	Cold shock
FNV59_RS03175	COG0596	Alpha beta hydrolase
FNV59_RS03220	COG3293	Transposase
FNV59_RS03240	COG3629	intracellular signal transduction
FNV59_RS03240	COG3903	Transcriptional regulator
FNV59_RS03260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FNV59_RS03290	COG0583	DNA-binding transcription factor activity
FNV59_RS03305	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FNV59_RS03320	COG0640	Transcriptional regulator
FNV59_RS03360	COG1609	Transcriptional regulator
FNV59_RS03365	COG2723	6-phospho-beta-galactosidase activity
FNV59_RS03395	COG3250	beta-galactosidase activity
FNV59_RS03400	COG3250	beta-galactosidase activity
FNV59_RS03415	COG3507	Belongs to the glycosyl hydrolase 43 family
FNV59_RS03425	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FNV59_RS03435	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS03470	COG3250	beta-galactosidase activity
FNV59_RS03520	COG3290	protein histidine kinase activity
FNV59_RS03540	COG1131	(ABC) transporter
FNV59_RS03550	COG1595	DNA-templated transcription, initiation
FNV59_RS03635	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FNV59_RS03645	COG1309	transcriptional regulator
FNV59_RS03720	COG0745	RESPONSE REGULATOR receiver
FNV59_RS03725	COG2205	protein histidine kinase activity
FNV59_RS03755	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FNV59_RS03780	COG4585	Histidine kinase
FNV59_RS03785	COG2197	response regulator
FNV59_RS03790	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS03815	COG1090	epimerase
FNV59_RS03820	COG1595	DNA-templated transcription, initiation
FNV59_RS03840	COG1250	3-hydroxyacyl-CoA dehydrogenase
FNV59_RS03850	COG1960	acyl-CoA dehydrogenase activity
FNV59_RS03890	COG0778	Nitroreductase
FNV59_RS03895	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FNV59_RS03930	COG1063	alcohol dehydrogenase
FNV59_RS03935	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FNV59_RS03935	COG2124	cytochrome p450
FNV59_RS03990	COG0656	L-ascorbic acid biosynthetic process
FNV59_RS04015	COG3344	reverse transcriptase
FNV59_RS04195	COG2890	protein-(glutamine-N5) methyltransferase activity
FNV59_RS04215	COG0069	glutamate synthase activity
FNV59_RS04220	COG0028	Belongs to the TPP enzyme family
FNV59_RS04225	COG0596	Alpha beta hydrolase
FNV59_RS04235	COG1366	Belongs to the anti-sigma-factor antagonist family
FNV59_RS04245	COG0277	FAD linked oxidase domain protein
FNV59_RS04250	COG1024	Enoyl-CoA hydratase
FNV59_RS04280	COG1120	ATPase activity
FNV59_RS04285	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FNV59_RS04295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FNV59_RS04300	COG1535	isochorismatase
FNV59_RS04300	COG3433	isochorismatase activity
FNV59_RS04320	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FNV59_RS04375	COG2226	methyltransferase
FNV59_RS04395	COG3321	synthase
FNV59_RS04395	COG0604	alcohol dehydrogenase
FNV59_RS04415	COG1522	sequence-specific DNA binding
FNV59_RS04430	COG0667	Aldo Keto reductase
FNV59_RS04465	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS04480	COG3537	Alpha-1,2-mannosidase
FNV59_RS04490	COG1309	transcriptional regulator
FNV59_RS04495	COG3619	membrane
FNV59_RS04500	COG0583	DNA-binding transcription factor activity
FNV59_RS04505	COG3876	Protein conserved in bacteria
FNV59_RS04520	COG1175	transmembrane transport
FNV59_RS04525	COG0395	ABC-type sugar transport system, permease component
FNV59_RS04535	COG1902	pentaerythritol trinitrate reductase activity
FNV59_RS04555	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNV59_RS04570	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FNV59_RS04580	COG1073	alpha beta
FNV59_RS04585	COG1024	Enoyl-CoA hydratase
FNV59_RS04595	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FNV59_RS04620	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS04645	COG1309	transcriptional regulator
FNV59_RS04650	COG0655	NAD(P)H dehydrogenase (quinone) activity
FNV59_RS04660	COG1733	regulation of RNA biosynthetic process
FNV59_RS04675	COG1309	transcriptional regulator
FNV59_RS04695	COG1960	acyl-CoA dehydrogenase activity
FNV59_RS04700	COG1960	acyl-CoA dehydrogenase activity
FNV59_RS04710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV59_RS04720	COG1960	acyl-CoA dehydrogenase activity
FNV59_RS04730	COG1024	Enoyl-CoA hydratase
FNV59_RS04735	COG0318	PFAM AMP-dependent synthetase and ligase
FNV59_RS04740	COG1309	transcriptional regulator
FNV59_RS04745	COG0667	Aldo Keto reductase
FNV59_RS04750	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FNV59_RS04775	COG0800	Aldolase
FNV59_RS04785	COG4948	Mandelate Racemase Muconate Lactonizing
FNV59_RS04805	COG0395	ABC-type sugar transport system, permease component
FNV59_RS04810	COG1175	transmembrane transport
FNV59_RS04820	COG3345	alpha-galactosidase
FNV59_RS04825	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FNV59_RS04855	COG1309	transcriptional regulator
FNV59_RS04900	COG0366	Alpha amylase catalytic
FNV59_RS04930	COG0583	DNA-binding transcription factor activity
FNV59_RS04940	COG2197	response regulator
FNV59_RS04955	COG1250	3-hydroxyacyl-CoA dehydrogenase
FNV59_RS04970	COG2207	Transcriptional regulator
FNV59_RS04975	COG2223	nitrite transmembrane transporter activity
FNV59_RS05005	COG1012	belongs to the aldehyde dehydrogenase family
FNV59_RS05030	COG1609	Transcriptional regulator
FNV59_RS05050	COG0395	ABC-type sugar transport system, permease component
FNV59_RS05100	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FNV59_RS05120	COG0488	(ABC) transporter
FNV59_RS05125	COG0488	(ABC) transporter
FNV59_RS05180	COG1764	response to oxidative stress
FNV59_RS05215	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FNV59_RS05240	COG0477	Major facilitator Superfamily
FNV59_RS05290	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FNV59_RS05290	COG0519	Catalyzes the synthesis of GMP from XMP
FNV59_RS05325	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS05330	COG2188	Transcriptional regulator
FNV59_RS05335	COG2182	Extracellular solute-binding protein
FNV59_RS05340	COG1175	transmembrane transport
FNV59_RS05345	COG0395	ABC-type sugar transport system, permease component
FNV59_RS05420	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FNV59_RS05430	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FNV59_RS05470	COG3469	chitinase activity
FNV59_RS05485	COG3903	Transcriptional regulator
FNV59_RS05485	COG3629	intracellular signal transduction
FNV59_RS05530	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS05535	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS05545	COG1764	response to oxidative stress
FNV59_RS05610	COG2208	phosphoserine phosphatase activity
FNV59_RS05610	COG2770	Histidine kinase
FNV59_RS05630	COG0583	DNA-binding transcription factor activity
FNV59_RS05645	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS05670	COG0702	epimerase
FNV59_RS05680	COG2271	Major facilitator Superfamily
FNV59_RS05685	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FNV59_RS05685	COG2755	lipolytic protein G-D-S-L family
FNV59_RS05690	COG3250	beta-galactosidase activity
FNV59_RS05725	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FNV59_RS05765	COG2197	response regulator
FNV59_RS05780	COG1082	Xylose isomerase domain protein TIM barrel
FNV59_RS05790	COG1082	Xylose isomerase domain protein TIM barrel
FNV59_RS05810	COG2226	methyltransferase
FNV59_RS05815	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FNV59_RS05830	COG0477	Major facilitator Superfamily
FNV59_RS05845	COG4213	ABC transporter substrate-binding protein
FNV59_RS05855	COG4213	ABC transporter substrate-binding protein
FNV59_RS05865	COG4214	carbohydrate transport
FNV59_RS05875	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FNV59_RS05880	COG1414	Transcriptional regulator
FNV59_RS05905	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FNV59_RS05910	COG0640	Transcriptional regulator
FNV59_RS05915	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FNV59_RS05920	COG0248	Ppx GppA phosphatase
FNV59_RS05930	COG1609	Transcriptional regulator
FNV59_RS05950	COG0395	ABC-type sugar transport system, permease component
FNV59_RS05965	COG0477	Major facilitator Superfamily
FNV59_RS05975	COG2124	cytochrome p450
FNV59_RS06050	COG1191	sigma factor activity
FNV59_RS06055	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FNV59_RS06135	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FNV59_RS06145	COG1064	alcohol dehydrogenase
FNV59_RS06175	COG0009	L-threonylcarbamoyladenylate synthase
FNV59_RS06185	COG0443	Heat shock 70 kDa protein
FNV59_RS06190	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FNV59_RS06205	COG0542	response to heat
FNV59_RS06220	COG1414	Transcriptional regulator
FNV59_RS06225	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FNV59_RS06230	COG2610	gluconate transmembrane transporter activity
FNV59_RS06235	COG4948	Mandelate Racemase Muconate Lactonizing
FNV59_RS06250	COG1136	(ABC) transporter
FNV59_RS06255	COG4585	Histidine kinase
FNV59_RS06260	COG2197	response regulator
FNV59_RS06265	COG1309	transcriptional regulator
FNV59_RS06270	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS06280	COG1595	DNA-templated transcription, initiation
FNV59_RS06335	COG2814	Major facilitator Superfamily
FNV59_RS06350	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FNV59_RS06355	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FNV59_RS06360	COG2186	Transcriptional regulator
FNV59_RS06380	COG5006	permease, DMT superfamily
FNV59_RS06395	COG0477	Major facilitator Superfamily
FNV59_RS06450	COG0464	growth
FNV59_RS06560	COG1846	Transcriptional regulator
FNV59_RS06560	COG1940	carbohydrate kinase activity
FNV59_RS06640	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FNV59_RS06660	COG4585	Histidine kinase
FNV59_RS06665	COG2197	response regulator
FNV59_RS06720	COG1881	PFAM PEBP family protein
FNV59_RS06735	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS06740	COG2186	Transcriptional regulator
FNV59_RS06745	COG1024	Enoyl-CoA hydratase
FNV59_RS06750	COG1960	acyl-CoA dehydrogenase activity
FNV59_RS06755	COG1960	acyl-CoA dehydrogenase activity
FNV59_RS06760	COG0318	PFAM AMP-dependent synthetase and ligase
FNV59_RS06765	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNV59_RS06770	COG1024	Enoyl-CoA hydratase
FNV59_RS06775	COG0183	Belongs to the thiolase family
FNV59_RS06780	COG1960	acyl-CoA dehydrogenase activity
FNV59_RS06785	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS06800	COG1024	Enoyl-CoA hydratase
FNV59_RS06805	COG1024	Enoyl-CoA hydratase
FNV59_RS06855	COG1960	acyl-CoA dehydrogenase activity
FNV59_RS06865	COG1960	acyl-CoA dehydrogenase activity
FNV59_RS06870	COG2272	Belongs to the type-B carboxylesterase lipase family
FNV59_RS06875	COG1024	Enoyl-CoA hydratase
FNV59_RS06890	COG0183	Belongs to the thiolase family
FNV59_RS06895	COG0318	PFAM AMP-dependent synthetase and ligase
FNV59_RS06915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV59_RS06920	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FNV59_RS06925	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FNV59_RS06925	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FNV59_RS06930	COG0318	PFAM AMP-dependent synthetase and ligase
FNV59_RS06940	COG0318	PFAM AMP-dependent synthetase and ligase
FNV59_RS06950	COG1024	Enoyl-CoA hydratase
FNV59_RS06960	COG1309	transcriptional regulator
FNV59_RS07000	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNV59_RS07005	COG1012	belongs to the aldehyde dehydrogenase family
FNV59_RS07020	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS07030	COG4638	Rieske (2fe-2S)
FNV59_RS07040	COG1228	amidohydrolase
FNV59_RS07050	COG1960	acyl-CoA dehydrogenase activity
FNV59_RS07060	COG0604	alcohol dehydrogenase
FNV59_RS07060	COG3321	synthase
FNV59_RS07060	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS07070	COG1960	acyl-CoA dehydrogenase activity
FNV59_RS07105	COG0745	RESPONSE REGULATOR receiver
FNV59_RS07110	COG1846	Transcriptional regulator
FNV59_RS07115	COG1309	transcriptional regulator
FNV59_RS07120	COG4585	Histidine kinase
FNV59_RS07125	COG2197	response regulator
FNV59_RS07145	COG2814	Major facilitator Superfamily
FNV59_RS07195	COG0277	FAD linked oxidase domain protein
FNV59_RS07210	COG0366	Alpha amylase catalytic
FNV59_RS07220	COG3281	Trehalose synthase
FNV59_RS07225	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FNV59_RS07255	COG1136	(ABC) transporter
FNV59_RS07255	COG0577	efflux transmembrane transporter activity
FNV59_RS07325	COG0477	Major facilitator Superfamily
FNV59_RS07345	COG0494	nUDIX hydrolase
FNV59_RS07470	COG0515	serine threonine protein kinase
FNV59_RS07470	COG2815	serine threonine protein kinase
FNV59_RS07485	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FNV59_RS07500	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FNV59_RS07515	COG1902	pentaerythritol trinitrate reductase activity
FNV59_RS07525	COG1216	Glycosyl transferase, family 2
FNV59_RS07525	COG1442	glycosyl transferase family 8
FNV59_RS07585	COG0475	glutathione-regulated potassium exporter activity
FNV59_RS07600	COG2124	cytochrome p450
FNV59_RS07775	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FNV59_RS07780	COG1793	dna ligase
FNV59_RS07820	COG3629	intracellular signal transduction
FNV59_RS07820	COG3903	Transcriptional regulator
FNV59_RS07885	COG1278	Cold shock
FNV59_RS07935	COG3344	reverse transcriptase
FNV59_RS07955	COG1484	DNA-dependent DNA replication
FNV59_RS07960	COG4584	PFAM Integrase catalytic
FNV59_RS08020	COG3345	alpha-galactosidase
FNV59_RS08025	COG0395	ABC-type sugar transport system, permease component
FNV59_RS08030	COG1175	transmembrane transport
FNV59_RS08040	COG1846	Transcriptional regulator
FNV59_RS08040	COG1940	carbohydrate kinase activity
FNV59_RS08055	COG0574	Belongs to the PEP-utilizing enzyme family
FNV59_RS08055	COG3848	Pyruvate phosphate dikinase
FNV59_RS08115	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FNV59_RS08120	COG1793	dna ligase
FNV59_RS08130	COG0539	negative regulation of cytoplasmic translation
FNV59_RS08155	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS08180	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FNV59_RS08230	COG2267	carboxylic ester hydrolase activity
FNV59_RS08320	COG2226	methyltransferase
FNV59_RS08410	COG0702	epimerase
FNV59_RS08500	COG3547	Transposase (IS116 IS110 IS902 family)
FNV59_RS08670	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FNV59_RS08675	COG3285	dna ligase
FNV59_RS08675	COG1793	dna ligase
FNV59_RS08725	COG2826	transposase and inactivated derivatives, IS30 family
FNV59_RS08770	COG2801	Transposase and inactivated derivatives
FNV59_RS08805	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FNV59_RS08865	COG3387	PFAM Glycoside hydrolase 15-related
FNV59_RS08890	COG0492	ferredoxin-NADP+ reductase activity
FNV59_RS08910	COG2409	Drug exporters of the RND superfamily
FNV59_RS08925	COG2197	response regulator
FNV59_RS08965	COG3655	Transcriptional regulator
FNV59_RS09030	COG1335	isochorismatase
FNV59_RS09040	COG3328	transposase activity
FNV59_RS09115	COG0832	Belongs to the urease beta subunit family
FNV59_RS09115	COG0831	urea catabolic process
FNV59_RS09120	COG0804	urea catabolic process
FNV59_RS09125	COG0830	nickel cation binding
FNV59_RS09130	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FNV59_RS09135	COG0829	nickel cation binding
FNV59_RS09145	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FNV59_RS09160	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FNV59_RS09210	COG1215	transferase activity, transferring glycosyl groups
FNV59_RS09225	COG0438	transferase activity, transferring glycosyl groups
FNV59_RS09230	COG0789	Transcriptional regulator
FNV59_RS09235	COG4221	oxidoreductase activity
FNV59_RS09255	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FNV59_RS09305	COG1618	nucleotide phosphatase activity, acting on free nucleotides
FNV59_RS09390	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FNV59_RS09425	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FNV59_RS09480	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FNV59_RS09585	COG2304	oxidoreductase activity
FNV59_RS09615	COG0328	RNA-DNA hybrid ribonuclease activity
FNV59_RS09655	COG3226	Transcriptional regulator
FNV59_RS09670	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNV59_RS09680	COG0747	negative chemotaxis
FNV59_RS09710	COG3835	regulator
FNV59_RS09715	COG2010	Cytochrome c
FNV59_RS09715	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FNV59_RS09720	COG2080	2 iron, 2 sulfur cluster binding
FNV59_RS09745	COG0009	L-threonylcarbamoyladenylate synthase
FNV59_RS09845	COG3547	Transposase (IS116 IS110 IS902 family)
FNV59_RS09860	COG0596	Alpha beta hydrolase
FNV59_RS09865	COG0740	serine-type endopeptidase activity
FNV59_RS09870	COG0740	serine-type endopeptidase activity
FNV59_RS09880	COG2318	DinB family
FNV59_RS09895	COG0784	Response regulator, receiver
FNV59_RS09900	COG4251	negative regulation of phosphorylation
FNV59_RS09960	COG0842	Transport permease protein
FNV59_RS09960	COG1131	(ABC) transporter
FNV59_RS09960	COG1716	ATPase activity
FNV59_RS09980	COG2207	Transcriptional regulator
FNV59_RS09990	COG0667	Aldo Keto reductase
FNV59_RS09995	COG0583	DNA-binding transcription factor activity
FNV59_RS10010	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FNV59_RS10015	COG0346	lactoylglutathione lyase activity
FNV59_RS10020	COG0671	phosphoesterase, PA-phosphatase related
FNV59_RS10030	COG0412	Dienelactone hydrolase
FNV59_RS10035	COG0667	Aldo Keto reductase
FNV59_RS10045	COG1012	belongs to the aldehyde dehydrogenase family
FNV59_RS10050	COG4941	Belongs to the sigma-70 factor family
FNV59_RS10065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV59_RS10075	COG0431	NADPH-dependent FMN reductase
FNV59_RS10095	COG0702	epimerase
FNV59_RS10180	COG0531	amino acid
FNV59_RS10185	COG1940	carbohydrate kinase activity
FNV59_RS10190	COG3250	beta-galactosidase activity
FNV59_RS10210	COG3345	alpha-galactosidase
FNV59_RS10215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNV59_RS10235	COG0667	Aldo Keto reductase
FNV59_RS10265	COG0367	asparagine synthase
FNV59_RS10270	COG0069	glutamate synthase activity
FNV59_RS10275	COG2235	arginine
FNV59_RS10290	COG0673	inositol 2-dehydrogenase activity
FNV59_RS10295	COG3511	phospholipase C
FNV59_RS10345	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FNV59_RS10345	COG1672	PFAM Archaeal ATPase
FNV59_RS10385	COG0318	PFAM AMP-dependent synthetase and ligase
FNV59_RS10390	COG2366	antibiotic biosynthetic process
FNV59_RS10400	COG2070	2-Nitropropane dioxygenase
FNV59_RS10410	COG0515	serine threonine protein kinase
FNV59_RS10420	COG1960	acyl-CoA dehydrogenase activity
FNV59_RS10445	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FNV59_RS10450	COG4171	peptide transport system, permease
FNV59_RS10460	COG0747	negative chemotaxis
FNV59_RS10475	COG0019	diaminopimelate decarboxylase activity
FNV59_RS10480	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FNV59_RS10485	COG0534	Mate efflux family protein
FNV59_RS10490	COG1609	Transcriptional regulator
FNV59_RS10505	COG2188	Transcriptional regulator
FNV59_RS10515	COG3962	Belongs to the TPP enzyme family
FNV59_RS10520	COG3718	enzyme involved in inositol metabolism
FNV59_RS10530	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNV59_RS10560	COG0028	Belongs to the TPP enzyme family
FNV59_RS10565	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS10570	COG2072	flavoprotein involved in K transport
FNV59_RS10575	COG4638	Rieske (2fe-2S)
FNV59_RS10580	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS10585	COG3386	PFAM SMP-30 Gluconolaconase
FNV59_RS10590	COG1960	acyl-CoA dehydrogenase activity
FNV59_RS10595	COG1960	acyl-CoA dehydrogenase activity
FNV59_RS10605	COG1960	acyl-CoA dehydrogenase activity
FNV59_RS10610	COG0604	alcohol dehydrogenase
FNV59_RS10620	COG0318	PFAM AMP-dependent synthetase and ligase
FNV59_RS10625	COG0427	acetyl-CoA hydrolase
FNV59_RS10645	COG2186	Transcriptional regulator
FNV59_RS10650	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS10660	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNV59_RS10665	COG1960	acyl-CoA dehydrogenase activity
FNV59_RS10700	COG1063	alcohol dehydrogenase
FNV59_RS10710	COG1335	isochorismatase
FNV59_RS10785	COG2072	flavoprotein involved in K transport
FNV59_RS10810	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FNV59_RS10815	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FNV59_RS10820	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FNV59_RS10830	COG0531	amino acid
FNV59_RS10880	COG0604	alcohol dehydrogenase
FNV59_RS10880	COG3321	synthase
FNV59_RS10890	COG1073	alpha beta
FNV59_RS10935	COG0363	glucosamine-6-phosphate deaminase activity
FNV59_RS10940	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FNV59_RS10960	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FNV59_RS10965	COG2376	Dihydroxyacetone kinase
FNV59_RS10970	COG1461	Dihydroxyacetone kinase
FNV59_RS10985	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS11015	COG0446	pyridine nucleotide-disulphide oxidoreductase
FNV59_RS11015	COG1902	pentaerythritol trinitrate reductase activity
FNV59_RS11020	COG2890	protein-(glutamine-N5) methyltransferase activity
FNV59_RS11035	COG0604	alcohol dehydrogenase
FNV59_RS11035	COG3321	synthase
FNV59_RS11040	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FNV59_RS11065	COG3458	cephalosporin-C deacetylase activity
FNV59_RS11075	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FNV59_RS11080	COG2188	Transcriptional regulator
FNV59_RS11090	COG2226	methyltransferase
FNV59_RS11095	COG0366	Alpha amylase catalytic
FNV59_RS11100	COG2267	carboxylic ester hydrolase activity
FNV59_RS11110	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS11115	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FNV59_RS11155	COG0179	Fumarylacetoacetate (FAA) hydrolase
FNV59_RS11170	COG4941	Belongs to the sigma-70 factor family
FNV59_RS11180	COG3795	YCII-related domain
FNV59_RS11190	COG0346	lactoylglutathione lyase activity
FNV59_RS11195	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS11205	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FNV59_RS11210	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FNV59_RS11215	COG1686	Belongs to the peptidase S11 family
FNV59_RS11220	COG5650	phosphatidylinositol metabolic process
FNV59_RS11230	COG2066	Belongs to the glutaminase family
FNV59_RS11245	COG1113	amino acid transport
FNV59_RS11255	COG1968	undecaprenyl-diphosphatase activity
FNV59_RS11260	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FNV59_RS11265	COG1993	acr, cog1993
FNV59_RS11270	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FNV59_RS11295	COG1175	transmembrane transport
FNV59_RS11300	COG0395	ABC-type sugar transport system, permease component
FNV59_RS11320	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FNV59_RS11335	COG1960	acyl-CoA dehydrogenase activity
FNV59_RS11345	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FNV59_RS11385	COG1215	transferase activity, transferring glycosyl groups
FNV59_RS11400	COG0633	Ferredoxin
FNV59_RS11400	COG3217	Mosc domain protein beta barrel domain protein
FNV59_RS11420	COG1349	DNA-binding transcription factor activity
FNV59_RS11445	COG0577	efflux transmembrane transporter activity
FNV59_RS11450	COG1136	(ABC) transporter
FNV59_RS11475	COG1940	carbohydrate kinase activity
FNV59_RS11485	COG2813	Specifically methylates the guanine in position
FNV59_RS11510	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FNV59_RS11515	COG1349	DNA-binding transcription factor activity
FNV59_RS11520	COG3537	Alpha-1,2-mannosidase
FNV59_RS11530	COG1174	glycine betaine transport
FNV59_RS11550	COG2018	Roadblock/LC7 domain
FNV59_RS11580	COG3320	Male sterility
FNV59_RS11580	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FNV59_RS11585	COG3321	synthase
FNV59_RS11585	COG0604	alcohol dehydrogenase
FNV59_RS11590	COG0318	PFAM AMP-dependent synthetase and ligase
FNV59_RS11600	COG0596	Alpha beta hydrolase
FNV59_RS11605	COG4565	transcriptional regulatory protein
FNV59_RS11610	COG3290	protein histidine kinase activity
FNV59_RS11620	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNV59_RS11650	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS11655	COG1271	oxidase subunit
FNV59_RS11710	COG3387	PFAM Glycoside hydrolase 15-related
FNV59_RS11730	COG2223	nitrite transmembrane transporter activity
FNV59_RS11755	COG2197	response regulator
FNV59_RS11760	COG4585	Histidine kinase
FNV59_RS11775	COG0445	tRNA wobble uridine modification
FNV59_RS11785	COG1660	Displays ATPase and GTPase activities
FNV59_RS11815	COG0395	ABC-type sugar transport system, permease component
FNV59_RS11830	COG3345	alpha-galactosidase
FNV59_RS11860	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FNV59_RS11885	COG0204	Acyl-transferase
FNV59_RS11915	COG0584	glycerophosphoryl diester phosphodiesterase
FNV59_RS11975	COG1309	transcriptional regulator
FNV59_RS12000	COG0640	Transcriptional regulator
FNV59_RS12005	COG1902	pentaerythritol trinitrate reductase activity
FNV59_RS12020	COG2197	response regulator
FNV59_RS12025	COG4585	Histidine kinase
FNV59_RS12030	COG3963	phosphatidate phosphatase activity
FNV59_RS12050	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FNV59_RS12050	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FNV59_RS12090	COG0714	Associated with various cellular activities
FNV59_RS12095	COG3552	Protein containing von Willebrand factor type A (VWA) domain
FNV59_RS12125	COG0596	Alpha beta hydrolase
FNV59_RS12130	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FNV59_RS12130	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FNV59_RS12135	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FNV59_RS12145	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FNV59_RS12160	COG2706	6-phosphogluconolactonase activity
FNV59_RS12165	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
FNV59_RS12200	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FNV59_RS12205	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FNV59_RS12210	COG2080	2 iron, 2 sulfur cluster binding
FNV59_RS12220	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FNV59_RS12235	COG2770	Histidine kinase
FNV59_RS12235	COG2208	phosphoserine phosphatase activity
FNV59_RS12255	COG0745	RESPONSE REGULATOR receiver
FNV59_RS12290	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS12350	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS12380	COG0667	Aldo Keto reductase
FNV59_RS12385	COG4221	oxidoreductase activity
FNV59_RS12405	COG0513	Belongs to the DEAD box helicase family
FNV59_RS12415	COG0432	Pfam Uncharacterised protein family UPF0047
FNV59_RS12420	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNV59_RS12425	COG1116	anion transmembrane transporter activity
FNV59_RS12435	COG2072	flavoprotein involved in K transport
FNV59_RS12445	COG1132	(ABC) transporter
FNV59_RS12455	COG1301	dicarboxylic acid transport
FNV59_RS12475	COG1132	(ABC) transporter
FNV59_RS12485	COG0254	rRNA binding
FNV59_RS12500	COG1946	Acyl-CoA thioesterase
FNV59_RS12510	COG2018	Roadblock/LC7 domain
FNV59_RS12575	COG3239	Fatty acid desaturase
FNV59_RS12580	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FNV59_RS12600	COG2115	Belongs to the xylose isomerase family
FNV59_RS12610	COG1940	carbohydrate kinase activity
FNV59_RS12610	COG1846	Transcriptional regulator
FNV59_RS12635	COG1012	belongs to the aldehyde dehydrogenase family
FNV59_RS12675	COG0515	serine threonine protein kinase
FNV59_RS12700	COG1960	acyl-CoA dehydrogenase activity
FNV59_RS12705	COG1960	acyl-CoA dehydrogenase activity
FNV59_RS12720	COG0492	ferredoxin-NADP+ reductase activity
FNV59_RS12725	COG1793	dna ligase
FNV59_RS12735	COG1012	belongs to the aldehyde dehydrogenase family
FNV59_RS12750	COG3424	synthase
FNV59_RS12755	COG2124	cytochrome p450
FNV59_RS12775	COG0242	peptide deformylase activity
FNV59_RS12785	COG3442	glutamine amidotransferase
FNV59_RS12790	COG0205	6-phosphofructokinase activity
FNV59_RS12815	COG3275	phosphorelay sensor kinase activity
FNV59_RS12820	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FNV59_RS12830	COG3279	Response regulator of the LytR AlgR family
FNV59_RS12840	COG1834	amidinotransferase
FNV59_RS12845	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FNV59_RS12855	COG1510	regulation of RNA biosynthetic process
FNV59_RS12865	COG1733	regulation of RNA biosynthetic process
FNV59_RS12880	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FNV59_RS12890	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FNV59_RS12915	COG0829	nickel cation binding
FNV59_RS12920	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FNV59_RS12930	COG0804	urea catabolic process
FNV59_RS12935	COG0832	Belongs to the urease beta subunit family
FNV59_RS12940	COG0831	urea catabolic process
FNV59_RS12950	COG0740	serine-type endopeptidase activity
FNV59_RS12990	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FNV59_RS12995	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FNV59_RS13000	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FNV59_RS13010	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FNV59_RS13015	COG2226	methyltransferase
FNV59_RS13090	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FNV59_RS13100	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FNV59_RS13105	COG3663	DNA glycosylase
FNV59_RS13125	COG4585	Histidine kinase
FNV59_RS13130	COG2197	response regulator
FNV59_RS13135	COG1940	carbohydrate kinase activity
FNV59_RS13140	COG2188	Transcriptional regulator
FNV59_RS13145	COG1595	DNA-templated transcription, initiation
FNV59_RS13160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FNV59_RS13175	COG0626	cystathionine gamma-synthase activity
FNV59_RS13195	COG0583	DNA-binding transcription factor activity
FNV59_RS13205	COG1522	sequence-specific DNA binding
FNV59_RS13210	COG0419	ATPase involved in DNA repair
FNV59_RS13215	COG0420	3'-5' exonuclease activity
FNV59_RS13220	COG1739	Uncharacterized protein family UPF0029
FNV59_RS13240	COG2197	response regulator
FNV59_RS13250	COG1960	acyl-CoA dehydrogenase activity
FNV59_RS13265	COG1832	CoA-binding protein
FNV59_RS13275	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FNV59_RS13280	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FNV59_RS13305	COG2326	polyphosphate kinase activity
FNV59_RS13335	COG0110	maltose O-acetyltransferase activity
FNV59_RS13355	COG1472	Belongs to the glycosyl hydrolase 3 family
FNV59_RS13370	COG1609	Transcriptional regulator
FNV59_RS13405	COG0076	glutamate decarboxylase activity
FNV59_RS13430	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FNV59_RS13445	COG0183	Belongs to the thiolase family
FNV59_RS13470	COG1968	undecaprenyl-diphosphatase activity
FNV59_RS13495	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS13515	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV59_RS13525	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FNV59_RS13535	COG2318	DinB family
FNV59_RS13550	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FNV59_RS13555	COG0747	negative chemotaxis
FNV59_RS13590	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FNV59_RS13600	COG1760	l-serine dehydratase
FNV59_RS13605	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FNV59_RS13610	COG0509	glycine decarboxylation via glycine cleavage system
FNV59_RS13650	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FNV59_RS13670	COG0517	IMP dehydrogenase activity
FNV59_RS13670	COG4175	Glycine betaine
FNV59_RS13675	COG1012	belongs to the aldehyde dehydrogenase family
FNV59_RS13695	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FNV59_RS13705	COG4638	Rieske (2fe-2S)
FNV59_RS13710	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FNV59_RS13720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNV59_RS13760	COG0697	spore germination
FNV59_RS13835	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FNV59_RS13835	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FNV59_RS13845	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FNV59_RS13865	COG1716	ATPase activity
FNV59_RS13885	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FNV59_RS13920	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FNV59_RS13935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FNV59_RS13940	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FNV59_RS13950	COG2816	NAD+ diphosphatase activity
FNV59_RS13955	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
FNV59_RS13965	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FNV59_RS13970	COG3706	GGDEF domain
FNV59_RS13975	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FNV59_RS13980	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FNV59_RS14000	COG2018	Roadblock/LC7 domain
FNV59_RS14050	COG2814	Major facilitator Superfamily
FNV59_RS14055	COG4336	lyase activity
FNV59_RS14060	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FNV59_RS14065	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FNV59_RS14070	COG1984	allophanate hydrolase subunit 2
FNV59_RS14075	COG2755	lipolytic protein G-D-S-L family
FNV59_RS14080	COG0438	transferase activity, transferring glycosyl groups
FNV59_RS14085	COG0438	transferase activity, transferring glycosyl groups
FNV59_RS14110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FNV59_RS14125	COG2270	Major facilitator Superfamily
FNV59_RS14140	COG0463	Glycosyl transferase, family 2
FNV59_RS14175	COG1960	acyl-CoA dehydrogenase activity
FNV59_RS14185	COG1309	transcriptional regulator
FNV59_RS14230	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FNV59_RS14235	COG0140	phosphoribosyl-ATP diphosphatase activity
FNV59_RS14240	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FNV59_RS14245	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FNV59_RS14245	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FNV59_RS14250	COG3201	nicotinamide mononucleotide transporter
FNV59_RS14260	COG1846	Transcriptional regulator
FNV59_RS14260	COG1940	carbohydrate kinase activity
FNV59_RS14265	COG2223	nitrite transmembrane transporter activity
FNV59_RS14280	COG2233	PERMEase
FNV59_RS14305	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FNV59_RS14325	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FNV59_RS14330	COG3842	ATPase activity
FNV59_RS14340	COG1176	ABC-type spermidine putrescine transport system, permease component I
FNV59_RS14350	COG2188	Transcriptional regulator
FNV59_RS14360	COG0531	amino acid
FNV59_RS14380	COG2390	Transcriptional regulator
FNV59_RS14385	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FNV59_RS14395	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FNV59_RS14415	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FNV59_RS14430	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FNV59_RS14445	COG0194	GDP metabolic process
FNV59_RS14455	COG0284	orotidine-5'-phosphate decarboxylase activity
FNV59_RS14460	COG0167	dihydroorotate dehydrogenase activity
FNV59_RS14465	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FNV59_RS14470	COG0505	Belongs to the CarA family
FNV59_RS14480	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FNV59_RS14485	COG0540	Belongs to the ATCase OTCase family
FNV59_RS14490	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FNV59_RS14500	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FNV59_RS14505	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FNV59_RS14510	COG0006	proline dipeptidase activity
FNV59_RS14520	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FNV59_RS14525	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FNV59_RS14530	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FNV59_RS14535	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FNV59_RS14540	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FNV59_RS14550	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FNV59_RS14555	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FNV59_RS14575	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FNV59_RS14590	COG1131	(ABC) transporter
FNV59_RS14600	COG4585	Histidine kinase
FNV59_RS14605	COG2197	response regulator
FNV59_RS14610	COG0124	histidyl-tRNA synthetase
FNV59_RS14620	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FNV59_RS14625	COG1196	nuclear chromosome segregation
FNV59_RS14630	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FNV59_RS14640	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FNV59_RS14645	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FNV59_RS14650	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FNV59_RS14660	COG2255	four-way junction helicase activity
FNV59_RS14665	COG0632	four-way junction helicase activity
FNV59_RS14670	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FNV59_RS14675	COG0217	transcriptional regulatory protein
FNV59_RS14680	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
FNV59_RS14685	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
FNV59_RS14705	COG0438	transferase activity, transferring glycosyl groups
FNV59_RS14715	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FNV59_RS14735	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FNV59_RS14740	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FNV59_RS14755	COG5002	protein histidine kinase activity
FNV59_RS14755	COG2176	DNA-directed DNA polymerase activity
FNV59_RS14785	COG0395	ABC-type sugar transport system, permease component
FNV59_RS14790	COG1175	transmembrane transport
FNV59_RS14845	COG0512	Glutamine amidotransferase of anthranilate synthase
FNV59_RS14845	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FNV59_RS14905	COG1648	precorrin-2 dehydrogenase activity
FNV59_RS14905	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FNV59_RS14910	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FNV59_RS14925	COG1464	Belongs to the NlpA lipoprotein family
FNV59_RS14930	COG2011	ABC-type metal ion transport system permease component
FNV59_RS14935	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FNV59_RS14970	COG0318	PFAM AMP-dependent synthetase and ligase
FNV59_RS14970	COG0204	Acyl-transferase
FNV59_RS14975	COG0477	Major facilitator Superfamily
FNV59_RS14990	COG0165	Argininosuccinate lyase
FNV59_RS14995	COG0137	argininosuccinate synthase activity
FNV59_RS15015	COG2205	protein histidine kinase activity
FNV59_RS15020	COG0745	RESPONSE REGULATOR receiver
FNV59_RS15050	COG1438	arginine binding
FNV59_RS15055	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FNV59_RS15060	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FNV59_RS15065	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FNV59_RS15070	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FNV59_RS15090	COG0789	Transcriptional regulator
FNV59_RS15120	COG0697	spore germination
FNV59_RS15130	COG1649	PFAM Uncharacterised BCR, COG1649
FNV59_RS15160	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FNV59_RS15160	COG0072	phenylalanine-tRNA ligase activity
FNV59_RS15165	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FNV59_RS15170	COG5002	protein histidine kinase activity
FNV59_RS15175	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FNV59_RS15180	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FNV59_RS15185	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FNV59_RS15190	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FNV59_RS15245	COG1012	belongs to the aldehyde dehydrogenase family
FNV59_RS15250	COG0174	glutamine synthetase
FNV59_RS15260	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FNV59_RS15300	COG4176	ABC-type proline glycine betaine transport system permease component
FNV59_RS15305	COG0517	IMP dehydrogenase activity
FNV59_RS15305	COG4175	Glycine betaine
FNV59_RS15310	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FNV59_RS15530	COG0564	pseudouridine synthase activity
FNV59_RS15560	COG1309	transcriptional regulator
FNV59_RS15600	COG0805	protein transport
FNV59_RS15605	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FNV59_RS15635	COG0545	Peptidyl-prolyl cis-trans isomerase
FNV59_RS15640	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
FNV59_RS15650	COG1609	Transcriptional regulator
FNV59_RS15655	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
FNV59_RS15660	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
FNV59_RS15675	COG4122	O-methyltransferase activity
FNV59_RS15680	COG1222	aaa ATPase
FNV59_RS15705	COG0517	IMP dehydrogenase activity
FNV59_RS15705	COG1994	Peptidase M50
FNV59_RS15715	COG2197	response regulator
FNV59_RS15725	COG4166	transmembrane transport
FNV59_RS15735	COG0646	methionine synthase
FNV59_RS15735	COG1410	methionine synthase
FNV59_RS15740	COG1414	Transcriptional regulator
FNV59_RS15745	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FNV59_RS15750	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FNV59_RS15755	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FNV59_RS15760	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
FNV59_RS15770	COG1129	ABC transporter
FNV59_RS15780	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
FNV59_RS15785	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
FNV59_RS15790	COG0235	Class ii aldolase
FNV59_RS15795	COG0235	Class ii aldolase
FNV59_RS15795	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FNV59_RS15800	COG2186	Transcriptional regulator
FNV59_RS15825	COG0215	cysteine-tRNA ligase activity
FNV59_RS15845	COG0598	Magnesium transport protein CorA
FNV59_RS15855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV59_RS15860	COG0667	Aldo Keto reductase
FNV59_RS15890	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FNV59_RS15905	COG0308	aminopeptidase N
FNV59_RS15910	COG3012	SEC-C Motif Domain Protein
FNV59_RS15915	COG2186	Transcriptional regulator
FNV59_RS15920	COG3265	gluconokinase activity
FNV59_RS15930	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS15935	COG1063	alcohol dehydrogenase
FNV59_RS15960	COG3573	Dehydrogenase
FNV59_RS15970	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FNV59_RS15975	COG2149	membrane
FNV59_RS16005	COG0318	PFAM AMP-dependent synthetase and ligase
FNV59_RS16015	COG3876	Protein conserved in bacteria
FNV59_RS16035	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FNV59_RS16035	COG0072	phenylalanine-tRNA ligase activity
FNV59_RS16040	COG0789	Transcriptional regulator
FNV59_RS16060	COG1960	acyl-CoA dehydrogenase activity
FNV59_RS16070	COG0640	Transcriptional regulator
FNV59_RS16075	COG0697	spore germination
FNV59_RS16100	COG2851	Citrate transporter
FNV59_RS16105	COG0243	molybdopterin cofactor binding
FNV59_RS16110	COG1309	transcriptional regulator
FNV59_RS16120	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FNV59_RS16125	COG2188	Transcriptional regulator
FNV59_RS16160	COG1595	DNA-templated transcription, initiation
FNV59_RS16180	COG0515	serine threonine protein kinase
FNV59_RS16180	COG2815	serine threonine protein kinase
FNV59_RS16185	COG2755	lipolytic protein G-D-S-L family
FNV59_RS16205	COG0726	polysaccharide deacetylase
FNV59_RS16205	COG1649	PFAM Uncharacterised BCR, COG1649
FNV59_RS16230	COG1725	Transcriptional regulator
FNV59_RS16270	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FNV59_RS16270	COG0662	Cupin 2, conserved barrel domain protein
FNV59_RS16275	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FNV59_RS16280	COG0587	DNA-directed DNA polymerase activity
FNV59_RS16290	COG0330	HflC and HflK could
FNV59_RS16305	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV59_RS16310	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV59_RS16315	COG1126	abc transporter atp-binding protein
FNV59_RS16325	COG0765	amino acid transport
FNV59_RS16330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNV59_RS16340	COG1799	cell septum assembly
FNV59_RS16345	COG1960	acyl-CoA dehydrogenase activity
FNV59_RS16350	COG0477	Major facilitator Superfamily
FNV59_RS16360	COG0671	phosphoesterase, PA-phosphatase related
FNV59_RS16370	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FNV59_RS16400	COG1129	ABC transporter
FNV59_RS16430	COG1160	GTP binding
FNV59_RS16440	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FNV59_RS16480	COG3541	Predicted nucleotidyltransferase
FNV59_RS16495	COG1187	pseudouridine synthase activity
FNV59_RS16500	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FNV59_RS16505	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FNV59_RS16520	COG0686	Belongs to the AlaDH PNT family
FNV59_RS16530	COG0494	nUDIX hydrolase
FNV59_RS16535	COG0504	CTP synthase activity
FNV59_RS16540	COG3387	PFAM Glycoside hydrolase 15-related
FNV59_RS16565	COG0497	DNA recombination
FNV59_RS16570	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FNV59_RS16590	COG1120	ATPase activity
FNV59_RS16595	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FNV59_RS16600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FNV59_RS16605	COG0647	UMP catabolic process
FNV59_RS16645	COG2094	Belongs to the DNA glycosylase MPG family
FNV59_RS16655	COG1881	PFAM PEBP family protein
FNV59_RS16675	COG1119	ATPase activity
FNV59_RS16690	COG2197	response regulator
FNV59_RS16700	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS16705	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FNV59_RS16715	COG1131	(ABC) transporter
FNV59_RS16715	COG1716	ATPase activity
FNV59_RS16715	COG0842	Transport permease protein
FNV59_RS16725	COG3830	Belongs to the UPF0237 family
FNV59_RS16725	COG0560	Phosphoserine phosphatase
FNV59_RS16730	COG0588	phosphoglycerate mutase activity
FNV59_RS16745	COG2186	Transcriptional regulator
FNV59_RS16755	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FNV59_RS16760	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS16775	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FNV59_RS16795	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FNV59_RS16800	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FNV59_RS16820	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNV59_RS16870	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FNV59_RS16885	COG3387	PFAM Glycoside hydrolase 15-related
FNV59_RS16935	COG0488	(ABC) transporter
FNV59_RS16965	COG0235	Class ii aldolase
FNV59_RS16985	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FNV59_RS16990	COG1492	cobalamin metabolic process
FNV59_RS17005	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
FNV59_RS17010	COG1797	cobyrinic acid a,c-diamide synthase activity
FNV59_RS17075	COG0765	amino acid transport
FNV59_RS17080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNV59_RS17085	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FNV59_RS17090	COG0456	acetyltransferase
FNV59_RS17095	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FNV59_RS17100	COG1917	Cupin 2, conserved barrel domain protein
FNV59_RS17105	COG5285	phytanoyl-CoA dioxygenase
FNV59_RS17110	COG3844	kynureninase activity
FNV59_RS17135	COG1414	Transcriptional regulator
FNV59_RS17145	COG0768	penicillin binding
FNV59_RS17150	COG2252	PERMEase
FNV59_RS17155	COG1595	DNA-templated transcription, initiation
FNV59_RS17170	COG4733	cellulase activity
FNV59_RS17210	COG4677	pectinesterase activity
FNV59_RS17215	COG3866	Pectate lyase
FNV59_RS17220	COG2755	lipolytic protein G-D-S-L family
FNV59_RS17225	COG1653	transport
FNV59_RS17245	COG0395	ABC-type sugar transport system, permease component
FNV59_RS17260	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FNV59_RS17265	COG1802	Transcriptional regulator
FNV59_RS17290	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FNV59_RS17295	COG1349	DNA-binding transcription factor activity
FNV59_RS17310	COG0395	ABC-type sugar transport system, permease component
FNV59_RS17315	COG1063	alcohol dehydrogenase
FNV59_RS17325	COG1309	transcriptional regulator
FNV59_RS17340	COG1802	Transcriptional regulator
FNV59_RS17380	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FNV59_RS17390	COG3973	AAA domain
FNV59_RS17405	COG2171	N-acyltransferase activity
FNV59_RS17410	COG3226	Transcriptional regulator
FNV59_RS17415	COG2076	Multidrug Resistance protein
FNV59_RS17430	COG2151	metal-sulfur cluster biosynthetic enzyme
FNV59_RS17435	COG0822	iron-sulfur transferase activity
FNV59_RS17440	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FNV59_RS17445	COG0396	ATPase activity
FNV59_RS17455	COG0719	Fe-S assembly protein
FNV59_RS17470	COG2746	aminoglycoside 3-N-acetyltransferase activity
FNV59_RS17475	COG1131	(ABC) transporter
FNV59_RS17500	COG0109	protoheme IX farnesyltransferase activity
FNV59_RS17515	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FNV59_RS17530	COG0363	glucosamine-6-phosphate deaminase activity
FNV59_RS17535	COG0395	ABC-type sugar transport system, permease component
FNV59_RS17540	COG1175	transmembrane transport
FNV59_RS17550	COG0366	Alpha amylase catalytic
FNV59_RS17555	COG1653	transport
FNV59_RS17560	COG1695	Transcriptional regulator
FNV59_RS17565	COG1136	(ABC) transporter
FNV59_RS17580	COG0166	Belongs to the GPI family
FNV59_RS17595	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FNV59_RS17600	COG0149	triose-phosphate isomerase activity
FNV59_RS17605	COG0126	phosphoglycerate kinase activity
FNV59_RS17610	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FNV59_RS17620	COG1481	regulation of sporulation
FNV59_RS17625	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FNV59_RS17630	COG1660	Displays ATPase and GTPase activities
FNV59_RS17635	COG0322	excinuclease ABC activity
FNV59_RS17650	COG1609	Transcriptional regulator
FNV59_RS17660	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FNV59_RS17675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNV59_RS17680	COG0765	amino acid transport
FNV59_RS17690	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FNV59_RS17695	COG0477	Major facilitator Superfamily
FNV59_RS17700	COG0387	Pfam Sodium calcium exchanger
FNV59_RS17720	COG0556	nucleotide-excision repair
FNV59_RS17730	COG0584	glycerophosphoryl diester phosphodiesterase
FNV59_RS17735	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FNV59_RS17755	COG2313	pseudouridylate synthase activity
FNV59_RS17765	COG2226	methyltransferase
FNV59_RS17770	COG0598	Magnesium transport protein CorA
FNV59_RS17800	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FNV59_RS17805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FNV59_RS17845	COG0402	S-adenosylhomocysteine deaminase activity
FNV59_RS17880	COG1953	Uracil, thiamine, allantoin
FNV59_RS17885	COG1802	Transcriptional regulator
FNV59_RS17890	COG2267	carboxylic ester hydrolase activity
FNV59_RS17900	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
FNV59_RS17930	COG0237	dephospho-CoA kinase activity
FNV59_RS17950	COG2226	methyltransferase
FNV59_RS17955	COG1643	Atp-dependent helicase
FNV59_RS17995	COG2050	protein possibly involved in aromatic compounds catabolism
FNV59_RS18055	COG0737	Belongs to the 5'-nucleotidase family
FNV59_RS18075	COG4566	intracellular signal transduction
FNV59_RS18080	COG1605	Chorismate mutase
FNV59_RS18080	COG0287	Prephenate dehydrogenase
FNV59_RS18115	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS18120	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS18125	COG1024	Enoyl-CoA hydratase
FNV59_RS18150	COG0183	Belongs to the thiolase family
FNV59_RS18155	COG1309	transcriptional regulator
FNV59_RS18165	COG1960	acyl-CoA dehydrogenase activity
FNV59_RS18170	COG1960	acyl-CoA dehydrogenase activity
FNV59_RS18175	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FNV59_RS18185	COG2304	oxidoreductase activity
FNV59_RS18200	COG1136	(ABC) transporter
FNV59_RS18200	COG4591	ABC-type transport system involved in lipoprotein release permease component
FNV59_RS18215	COG0577	efflux transmembrane transporter activity
FNV59_RS18215	COG1136	(ABC) transporter
FNV59_RS18225	COG0069	glutamate synthase activity
FNV59_RS18225	COG0067	glutamate synthase
FNV59_RS18225	COG0070	glutamate synthase
FNV59_RS18255	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNV59_RS18260	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNV59_RS18265	COG2301	Belongs to the HpcH HpaI aldolase family
FNV59_RS18270	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FNV59_RS18280	COG0159	tryptophan synthase activity
FNV59_RS18285	COG0133	tryptophan synthase activity
FNV59_RS18295	COG0134	indole-3-glycerol-phosphate synthase activity
FNV59_RS18320	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FNV59_RS18340	COG0107	imidazoleglycerol-phosphate synthase activity
FNV59_RS18345	COG0251	oxidation-reduction process
FNV59_RS18350	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FNV59_RS18355	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FNV59_RS18360	COG0131	Imidazoleglycerol-phosphate dehydratase
FNV59_RS18365	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FNV59_RS18370	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FNV59_RS18390	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FNV59_RS18410	COG1432	Conserved Protein
FNV59_RS18415	COG0587	DNA-directed DNA polymerase activity
FNV59_RS18470	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FNV59_RS18485	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FNV59_RS18490	COG3599	regulation of cell shape
FNV59_RS18500	COG1799	cell septum assembly
FNV59_RS18510	COG1496	oxidoreductase activity
FNV59_RS18515	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FNV59_RS18530	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FNV59_RS18540	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FNV59_RS18545	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FNV59_RS18555	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FNV59_RS18560	COG0768	penicillin binding
FNV59_RS18570	COG0275	rRNA processing
FNV59_RS18580	COG0714	Associated with various cellular activities
FNV59_RS18600	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FNV59_RS18610	COG1126	abc transporter atp-binding protein
FNV59_RS18620	COG1309	transcriptional regulator
FNV59_RS18645	COG0352	thiamine-phosphate diphosphorylase activity
FNV59_RS18665	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNV59_RS18665	COG2022	thiamine diphosphate biosynthetic process
FNV59_RS18675	COG2022	thiamine diphosphate biosynthetic process
FNV59_RS18680	COG0515	serine threonine protein kinase
FNV59_RS18680	COG2815	serine threonine protein kinase
FNV59_RS18685	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FNV59_RS18690	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FNV59_RS18695	COG2193	ferroxidase activity
FNV59_RS18700	COG0243	molybdopterin cofactor binding
FNV59_RS18705	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FNV59_RS18725	COG0205	6-phosphofructokinase activity
FNV59_RS18730	COG2197	response regulator
FNV59_RS18735	COG4585	Histidine kinase
FNV59_RS18760	COG1940	carbohydrate kinase activity
FNV59_RS18770	COG0003	Pfam Anion-transporting ATPase
FNV59_RS18810	COG0534	Mate efflux family protein
FNV59_RS18830	COG3103	Sh3 type 3 domain protein
FNV59_RS18830	COG0791	NLP P60 protein
FNV59_RS18830	COG1388	LysM domain
FNV59_RS18855	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FNV59_RS18860	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FNV59_RS18865	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FNV59_RS18870	COG0723	plastoquinol--plastocyanin reductase activity
FNV59_RS18875	COG2010	Cytochrome c
FNV59_RS18880	COG1845	cytochrome c oxidase, subunit III
FNV59_RS18890	COG1376	ErfK ybiS ycfS ynhG family protein
FNV59_RS18900	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FNV59_RS18905	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FNV59_RS18915	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNV59_RS18940	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FNV59_RS18945	COG2197	response regulator
FNV59_RS18970	COG2226	methyltransferase
FNV59_RS18975	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FNV59_RS18995	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FNV59_RS19000	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FNV59_RS19000	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FNV59_RS19015	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FNV59_RS19020	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FNV59_RS19025	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FNV59_RS19030	COG0508	dehydrogenase complex catalyzes the overall conversion of
FNV59_RS19045	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FNV59_RS19075	COG0454	-acetyltransferase
FNV59_RS19095	COG0321	lipoyl(octanoyl) transferase activity
FNV59_RS19100	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FNV59_RS19120	COG0174	glutamine synthetase
FNV59_RS19130	COG0501	Belongs to the peptidase M48B family
FNV59_RS19180	COG0745	RESPONSE REGULATOR receiver
FNV59_RS19195	COG2197	response regulator
FNV59_RS19225	COG1309	transcriptional regulator
FNV59_RS19260	COG1175	transmembrane transport
FNV59_RS19265	COG3833	ABC-type maltose transport systems, permease component
FNV59_RS19270	COG0366	Alpha amylase catalytic
FNV59_RS19275	COG1609	Transcriptional regulator
FNV59_RS19285	COG0583	DNA-binding transcription factor activity
FNV59_RS19290	COG0697	spore germination
FNV59_RS19295	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FNV59_RS19300	COG3511	phospholipase C
FNV59_RS19340	COG0174	glutamine synthetase
FNV59_RS19345	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FNV59_RS19345	COG1017	nitric oxide dioxygenase activity
FNV59_RS19350	COG1959	2 iron, 2 sulfur cluster binding
FNV59_RS19370	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FNV59_RS19370	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FNV59_RS19375	COG2814	Major facilitator Superfamily
FNV59_RS19390	COG0477	Major facilitator Superfamily
FNV59_RS19395	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FNV59_RS19415	COG1994	Peptidase M50
FNV59_RS19470	COG2822	iron ion transport
FNV59_RS19475	COG2837	iron assimilation
FNV59_RS19480	COG0672	)-iron permease
FNV59_RS19490	COG0495	leucyl-tRNA aminoacylation
FNV59_RS19500	COG1834	amidinotransferase
FNV59_RS19510	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FNV59_RS19515	COG2814	Major facilitator Superfamily
FNV59_RS19530	COG1686	Belongs to the peptidase S11 family
FNV59_RS19540	COG1136	(ABC) transporter
FNV59_RS19545	COG0667	Aldo Keto reductase
FNV59_RS19555	COG2259	Doxx family
FNV59_RS19570	COG0406	alpha-ribazole phosphatase activity
FNV59_RS19580	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS19585	COG0673	inositol 2-dehydrogenase activity
FNV59_RS19595	COG0583	DNA-binding transcription factor activity
FNV59_RS19620	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FNV59_RS19650	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FNV59_RS19725	COG3022	response to hydroperoxide
FNV59_RS19730	COG0800	Aldolase
FNV59_RS19755	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FNV59_RS19770	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS19780	COG2030	dehydratase
FNV59_RS19785	COG1131	(ABC) transporter
FNV59_RS19795	COG4585	Histidine kinase
FNV59_RS19805	COG2197	response regulator
FNV59_RS19825	COG0183	Belongs to the thiolase family
FNV59_RS19830	COG0477	Major facilitator Superfamily
FNV59_RS19840	COG0860	N-Acetylmuramoyl-L-alanine amidase
FNV59_RS19850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV59_RS19875	COG0438	transferase activity, transferring glycosyl groups
FNV59_RS19880	COG1309	transcriptional regulator
FNV59_RS19940	COG3845	ABC transporter
FNV59_RS19960	COG3619	membrane
FNV59_RS19985	COG0183	Belongs to the thiolase family
FNV59_RS19990	COG2124	cytochrome p450
FNV59_RS20010	COG4122	O-methyltransferase activity
FNV59_RS20090	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FNV59_RS20095	COG1335	isochorismatase
FNV59_RS20100	COG0477	Major facilitator Superfamily
FNV59_RS20120	COG1733	regulation of RNA biosynthetic process
FNV59_RS20225	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FNV59_RS20240	COG1358	cellular component organization or biogenesis
FNV59_RS20290	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FNV59_RS20295	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FNV59_RS20300	COG0477	Major facilitator Superfamily
FNV59_RS20305	COG1309	transcriptional regulator
FNV59_RS20320	COG0667	Aldo Keto reductase
FNV59_RS20325	COG0789	Transcriptional regulator
FNV59_RS20340	COG1741	Belongs to the pirin family
FNV59_RS20355	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FNV59_RS20360	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FNV59_RS20365	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FNV59_RS20395	COG1309	transcriptional regulator
FNV59_RS20410	COG2084	Dehydrogenase
FNV59_RS20445	COG1764	response to oxidative stress
FNV59_RS20450	COG2130	NADP-dependent
FNV59_RS20465	COG4948	Mandelate Racemase Muconate Lactonizing
FNV59_RS20490	COG4214	carbohydrate transport
FNV59_RS20500	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FNV59_RS20535	COG1764	response to oxidative stress
FNV59_RS20565	COG0596	Alpha beta hydrolase
FNV59_RS20585	COG2318	DinB family
FNV59_RS20610	COG3507	Belongs to the glycosyl hydrolase 43 family
FNV59_RS20615	COG0395	ABC-type sugar transport system, permease component
FNV59_RS20620	COG1175	transmembrane transport
FNV59_RS20630	COG3386	PFAM SMP-30 Gluconolaconase
FNV59_RS20635	COG1414	Transcriptional regulator
FNV59_RS20660	COG4981	capsule polysaccharide biosynthetic process
FNV59_RS20735	COG0318	PFAM AMP-dependent synthetase and ligase
FNV59_RS20740	COG0825	malonyl-CoA metabolic process
FNV59_RS20740	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FNV59_RS20745	COG1404	Belongs to the peptidase S8 family
FNV59_RS20750	COG1077	Cell shape determining protein MreB Mrl
FNV59_RS20790	COG0559	Belongs to the binding-protein-dependent transport system permease family
FNV59_RS20810	COG0318	PFAM AMP-dependent synthetase and ligase
FNV59_RS20845	COG1070	Carbohydrate kinase
FNV59_RS20860	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FNV59_RS20865	COG0358	DNA primase activity
FNV59_RS20875	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FNV59_RS20885	COG2949	membrane
FNV59_RS20950	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FNV59_RS20950	COG2146	nitrite reductase [NAD(P)H] activity
FNV59_RS20960	COG1309	transcriptional regulator
FNV59_RS20965	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS20970	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS20980	COG1136	(ABC) transporter
FNV59_RS21000	COG0574	Belongs to the PEP-utilizing enzyme family
FNV59_RS21000	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FNV59_RS21005	COG1846	Transcriptional regulator
FNV59_RS21005	COG1940	carbohydrate kinase activity
FNV59_RS21040	COG0477	Major facilitator Superfamily
FNV59_RS21070	COG0667	Aldo Keto reductase
FNV59_RS21080	COG1309	transcriptional regulator
FNV59_RS21085	COG0300	oxidoreductase activity
FNV59_RS21090	COG0423	glycine-tRNA ligase activity
FNV59_RS21095	COG0803	Belongs to the bacterial solute-binding protein 9 family
FNV59_RS21100	COG1121	(ABC) transporter
FNV59_RS21105	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FNV59_RS21115	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FNV59_RS21120	COG1381	Involved in DNA repair and RecF pathway recombination
FNV59_RS21130	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FNV59_RS21130	COG0515	serine threonine protein kinase
FNV59_RS21165	COG0456	acetyltransferase
FNV59_RS21170	COG2197	response regulator
FNV59_RS21175	COG4585	Histidine kinase
FNV59_RS21180	COG1131	(ABC) transporter
FNV59_RS21195	COG2186	Transcriptional regulator
FNV59_RS21200	COG0747	negative chemotaxis
FNV59_RS21210	COG0444	Belongs to the ABC transporter superfamily
FNV59_RS21215	COG4608	Belongs to the ABC transporter superfamily
FNV59_RS21220	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FNV59_RS21235	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FNV59_RS21255	COG2723	6-phospho-beta-galactosidase activity
FNV59_RS21300	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FNV59_RS21320	COG2315	Protein conserved in bacteria
FNV59_RS21330	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FNV59_RS21350	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FNV59_RS21355	COG1234	tRNA 3'-trailer cleavage
FNV59_RS21360	COG0537	adenosine 5'-monophosphoramidase activity
FNV59_RS21365	COG0793	Belongs to the peptidase S41A family
FNV59_RS21365	COG4946	Tricorn protease homolog
FNV59_RS21390	COG0484	heat shock protein binding
FNV59_RS21395	COG1420	regulation of RNA biosynthetic process
FNV59_RS21435	COG0481	GTPase activity
FNV59_RS21440	COG0268	Binds directly to 16S ribosomal RNA
FNV59_RS21465	COG1596	polysaccharide export
FNV59_RS21465	COG1555	photosystem II stabilization
FNV59_RS21470	COG1307	EDD domain protein, DegV family
FNV59_RS21480	COG0495	leucyl-tRNA aminoacylation
FNV59_RS21520	COG0477	Major facilitator Superfamily
FNV59_RS21535	COG0588	phosphoglycerate mutase activity
FNV59_RS21540	COG0799	negative regulation of ribosome biogenesis
FNV59_RS21550	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FNV59_RS21555	COG0501	Belongs to the peptidase M48B family
FNV59_RS21570	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FNV59_RS21580	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FNV59_RS21590	COG0438	transferase activity, transferring glycosyl groups
FNV59_RS21595	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FNV59_RS21595	COG0463	Glycosyl transferase, family 2
FNV59_RS21600	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FNV59_RS21600	COG0463	Glycosyl transferase, family 2
FNV59_RS21615	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FNV59_RS21620	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FNV59_RS21625	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FNV59_RS21630	COG1530	ribonuclease E activity
FNV59_RS21660	COG1309	transcriptional regulator
FNV59_RS21665	COG0300	oxidoreductase activity
FNV59_RS21680	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FNV59_RS21690	COG0640	Transcriptional regulator
FNV59_RS21695	COG2226	methyltransferase
FNV59_RS21705	COG0477	Major facilitator Superfamily
FNV59_RS21735	COG0772	Belongs to the SEDS family
FNV59_RS21740	COG0768	penicillin binding
FNV59_RS21755	COG1077	Cell shape determining protein MreB Mrl
FNV59_RS21760	COG0105	UTP biosynthetic process
FNV59_RS21770	COG0285	dihydrofolate synthase activity
FNV59_RS21775	COG0525	valine-tRNA ligase activity
FNV59_RS21785	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FNV59_RS21790	COG0740	serine-type endopeptidase activity
FNV59_RS21795	COG0740	serine-type endopeptidase activity
FNV59_RS21800	COG0544	peptidyl-prolyl cis-trans isomerase activity
FNV59_RS21825	COG3594	Acyltransferase
FNV59_RS21840	COG4552	Acetyltransferase involved in intracellular survival and related
FNV59_RS21855	COG1113	amino acid transport
FNV59_RS21860	COG0515	serine threonine protein kinase
FNV59_RS21870	COG1268	BioY protein
FNV59_RS21875	COG1940	carbohydrate kinase activity
FNV59_RS21885	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNV59_RS21890	COG1116	anion transmembrane transporter activity
FNV59_RS21895	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV59_RS21905	COG1113	amino acid transport
FNV59_RS21910	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FNV59_RS21915	COG0588	phosphoglycerate mutase activity
FNV59_RS21925	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FNV59_RS22005	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FNV59_RS22040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FNV59_RS22065	COG1122	ATPase activity
FNV59_RS22090	COG0668	transmembrane transport
FNV59_RS22125	COG1175	transmembrane transport
FNV59_RS22130	COG0395	ABC-type sugar transport system, permease component
FNV59_RS22135	COG1486	melibiose metabolic process
FNV59_RS22150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNV59_RS22180	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FNV59_RS22185	COG2346	COG2346, Truncated hemoglobins
FNV59_RS22225	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FNV59_RS22230	COG0489	protein tyrosine kinase activity
FNV59_RS22250	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FNV59_RS22275	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FNV59_RS22305	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FNV59_RS22315	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
FNV59_RS22405	COG0629	single-stranded DNA binding
FNV59_RS22510	COG3962	Belongs to the TPP enzyme family
FNV59_RS22515	COG3718	enzyme involved in inositol metabolism
FNV59_RS22525	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNV59_RS22550	COG2409	Drug exporters of the RND superfamily
FNV59_RS22580	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FNV59_RS22605	COG1129	ABC transporter
FNV59_RS22615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNV59_RS22620	COG1869	D-ribose catabolic process
FNV59_RS22640	COG0673	inositol 2-dehydrogenase activity
FNV59_RS22645	COG1609	Transcriptional regulator
FNV59_RS22650	COG1846	Transcriptional regulator
FNV59_RS22650	COG0456	acetyltransferase
FNV59_RS22660	COG0181	hydroxymethylbilane synthase activity
FNV59_RS22665	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FNV59_RS22670	COG1472	Belongs to the glycosyl hydrolase 3 family
FNV59_RS22710	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FNV59_RS22715	COG2356	endonuclease I
FNV59_RS22720	COG0028	Belongs to the TPP enzyme family
FNV59_RS22730	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FNV59_RS22750	COG1946	Acyl-CoA thioesterase
FNV59_RS22760	COG1309	transcriptional regulator
FNV59_RS22765	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FNV59_RS22780	COG1960	acyl-CoA dehydrogenase activity
FNV59_RS22815	COG0076	glutamate decarboxylase activity
FNV59_RS22820	COG3486	L-lysine 6-monooxygenase (NADPH) activity
FNV59_RS22855	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FNV59_RS22865	COG0589	response to stress
FNV59_RS22875	COG4977	sequence-specific DNA binding
FNV59_RS22880	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FNV59_RS22915	COG0395	ABC-type sugar transport system, permease component
FNV59_RS22930	COG3979	chitinase
FNV59_RS22940	COG0745	RESPONSE REGULATOR receiver
FNV59_RS22965	COG0406	alpha-ribazole phosphatase activity
FNV59_RS23015	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV59_RS23050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNV59_RS23055	COG0765	amino acid transport
FNV59_RS23060	COG0765	amino acid transport
FNV59_RS23065	COG1126	abc transporter atp-binding protein
FNV59_RS23080	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FNV59_RS23095	COG1362	aminopeptidase activity
FNV59_RS23115	COG0318	PFAM AMP-dependent synthetase and ligase
FNV59_RS23125	COG3397	chitin binding
FNV59_RS23200	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNV59_RS23205	COG2188	Transcriptional regulator
FNV59_RS23220	COG0673	inositol 2-dehydrogenase activity
FNV59_RS23225	COG4702	Belongs to the UPF0303 family
FNV59_RS23235	COG4455	Protein of avirulence locus involved in temperature-dependent protein secretion
FNV59_RS23235	COG0706	membrane insertase activity
FNV59_RS23255	COG3764	Sortase (surface protein transpeptidase)
FNV59_RS23265	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FNV59_RS23285	COG0270	DNA (cytosine-5-)-methyltransferase activity
FNV59_RS23315	COG1074	ATP-dependent DNA helicase activity
FNV59_RS23350	COG0590	tRNA wobble adenosine to inosine editing
FNV59_RS23360	COG1403	HNH endonuclease
FNV59_RS23375	COG3250	beta-galactosidase activity
FNV59_RS23390	COG1846	Transcriptional regulator
FNV59_RS23420	COG2733	membrane
FNV59_RS23435	COG1131	(ABC) transporter
FNV59_RS23450	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FNV59_RS23485	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FNV59_RS23495	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FNV59_RS23500	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FNV59_RS23505	COG1263	PTS System
FNV59_RS23510	COG1263	PTS System
FNV59_RS23525	COG3631	Ketosteroid isomerase-related protein
FNV59_RS23565	COG1113	amino acid transport
FNV59_RS23580	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FNV59_RS23590	COG1335	isochorismatase
FNV59_RS23625	COG0277	FAD linked oxidase domain protein
FNV59_RS23635	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FNV59_RS23645	COG1174	glycine betaine transport
FNV59_RS23665	COG3480	Lon protease (S16) C-terminal proteolytic domain
FNV59_RS23670	COG4948	Mandelate Racemase Muconate Lactonizing
FNV59_RS23680	COG0049	tRNA binding
FNV59_RS23690	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FNV59_RS23690	COG0596	Alpha beta hydrolase
FNV59_RS23700	COG0531	amino acid
FNV59_RS23750	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FNV59_RS23755	COG0395	ABC-type sugar transport system, permease component
FNV59_RS23760	COG1175	transmembrane transport
FNV59_RS23765	COG1653	transport
FNV59_RS23775	COG1678	Uncharacterized ACR, COG1678
FNV59_RS23780	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FNV59_RS23785	COG0776	regulation of translation
FNV59_RS23795	COG3973	AAA domain
FNV59_RS23825	COG2223	nitrite transmembrane transporter activity
FNV59_RS23845	COG0583	DNA-binding transcription factor activity
FNV59_RS23860	COG1175	transmembrane transport
FNV59_RS23865	COG0395	ABC-type sugar transport system, permease component
FNV59_RS23870	COG1501	Belongs to the glycosyl hydrolase 31 family
FNV59_RS23875	COG1609	Transcriptional regulator
FNV59_RS23900	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FNV59_RS23905	COG0793	Belongs to the peptidase S41A family
FNV59_RS23915	COG2884	Cell division ATP-binding protein ftsE
FNV59_RS23930	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FNV59_RS23935	COG0515	serine threonine protein kinase
FNV59_RS23940	COG0515	serine threonine protein kinase
FNV59_RS23960	COG1175	transmembrane transport
FNV59_RS23965	COG0395	ABC-type sugar transport system, permease component
FNV59_RS23970	COG0463	Glycosyl transferase, family 2
FNV59_RS23970	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FNV59_RS23975	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FNV59_RS23995	COG1764	response to oxidative stress
FNV59_RS24000	COG1846	Transcriptional regulator
FNV59_RS24015	COG1216	Glycosyl transferase, family 2
FNV59_RS24040	COG2197	response regulator
FNV59_RS24065	COG1134	teichoic acid transport
FNV59_RS24070	COG0438	transferase activity, transferring glycosyl groups
FNV59_RS24075	COG0463	Glycosyl transferase, family 2
FNV59_RS24075	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FNV59_RS24085	COG2902	Dehydrogenase
FNV59_RS24110	COG0653	protein targeting
FNV59_RS24120	COG3214	Protein conserved in bacteria
FNV59_RS24125	COG2197	response regulator
FNV59_RS24130	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FNV59_RS24140	COG0823	Involved in the tonB-independent uptake of proteins
FNV59_RS24145	COG5000	phosphorelay sensor kinase activity
FNV59_RS24145	COG5002	protein histidine kinase activity
FNV59_RS24150	COG0745	RESPONSE REGULATOR receiver
FNV59_RS24155	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FNV59_RS24175	COG0714	Associated with various cellular activities
FNV59_RS24220	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FNV59_RS24230	COG1482	cell wall glycoprotein biosynthetic process
FNV59_RS24240	COG2835	tetraacyldisaccharide 4'-kinase activity
FNV59_RS24245	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FNV59_RS24290	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FNV59_RS24295	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
FNV59_RS24295	COG0778	Nitroreductase
FNV59_RS24310	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FNV59_RS24330	COG1316	TRANSCRIPTIONal
FNV59_RS24350	COG1316	TRANSCRIPTIONal
FNV59_RS24360	COG1011	Hydrolase
FNV59_RS24375	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FNV59_RS24420	COG2205	protein histidine kinase activity
FNV59_RS24425	COG0745	RESPONSE REGULATOR receiver
FNV59_RS24430	COG3104	oligopeptide transport
FNV59_RS24485	COG1366	Belongs to the anti-sigma-factor antagonist family
FNV59_RS24490	COG1191	sigma factor activity
FNV59_RS24500	COG1228	amidohydrolase
FNV59_RS24510	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FNV59_RS24515	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FNV59_RS24560	COG2986	histidine ammonia-lyase
FNV59_RS24570	COG1174	glycine betaine transport
FNV59_RS24575	COG1174	glycine betaine transport
FNV59_RS24585	COG1609	Transcriptional regulator
FNV59_RS24600	COG0288	reversible hydration of carbon dioxide
FNV59_RS24615	COG2755	lipolytic protein G-D-S-L family
FNV59_RS24620	COG0183	Belongs to the thiolase family
FNV59_RS24665	COG1136	(ABC) transporter
FNV59_RS24665	COG0577	efflux transmembrane transporter activity
FNV59_RS24670	COG0577	efflux transmembrane transporter activity
FNV59_RS24675	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FNV59_RS24680	COG1252	NADH dehydrogenase
FNV59_RS24700	COG0148	phosphopyruvate hydratase activity
FNV59_RS24715	COG2124	cytochrome p450
FNV59_RS24855	COG1309	transcriptional regulator
FNV59_RS24870	COG0577	efflux transmembrane transporter activity
FNV59_RS24875	COG1136	(ABC) transporter
FNV59_RS24880	COG0477	Major facilitator Superfamily
FNV59_RS24890	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FNV59_RS24920	COG4585	Histidine kinase
FNV59_RS24935	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FNV59_RS24940	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FNV59_RS24945	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FNV59_RS24950	COG0193	aminoacyl-tRNA hydrolase activity
FNV59_RS24960	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FNV59_RS24970	COG1309	transcriptional regulator
FNV59_RS24980	COG4106	trans-aconitate 2-methyltransferase activity
FNV59_RS24990	COG2197	response regulator
FNV59_RS25000	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FNV59_RS25045	COG0488	(ABC) transporter
FNV59_RS25055	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FNV59_RS25060	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FNV59_RS25070	COG0084	hydrolase, TatD family'
FNV59_RS25115	COG3224	Antibiotic biosynthesis monooxygenase
FNV59_RS25120	COG0590	tRNA wobble adenosine to inosine editing
FNV59_RS25125	COG0768	penicillin binding
FNV59_RS25150	COG0310	cobalt ion transport
FNV59_RS25160	COG1122	ATPase activity
FNV59_RS25165	COG1846	Transcriptional regulator
FNV59_RS25170	COG1764	response to oxidative stress
FNV59_RS25195	COG0667	Aldo Keto reductase
FNV59_RS25205	COG2409	Drug exporters of the RND superfamily
FNV59_RS25215	COG4946	Tricorn protease homolog
FNV59_RS25215	COG0793	Belongs to the peptidase S41A family
FNV59_RS25225	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS25230	COG2267	carboxylic ester hydrolase activity
FNV59_RS25235	COG2072	flavoprotein involved in K transport
FNV59_RS25245	COG0708	Exodeoxyribonuclease III
FNV59_RS25265	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FNV59_RS25270	COG0315	cyclic pyranopterin monophosphate synthase activity
FNV59_RS25270	COG0521	Mo-molybdopterin cofactor biosynthetic process
FNV59_RS25275	COG0315	cyclic pyranopterin monophosphate synthase activity
FNV59_RS25285	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FNV59_RS25290	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FNV59_RS25300	COG3263	regulation of cellular component size
FNV59_RS25320	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FNV59_RS25330	COG1970	mechanosensitive ion channel activity
FNV59_RS25350	COG1376	ErfK ybiS ycfS ynhG family protein
FNV59_RS25365	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FNV59_RS25365	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FNV59_RS25365	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FNV59_RS25375	COG1349	DNA-binding transcription factor activity
FNV59_RS25385	COG0477	Major facilitator Superfamily
FNV59_RS25405	COG1247	-acetyltransferase
FNV59_RS25410	COG3384	dioxygenase
FNV59_RS25415	COG1846	Transcriptional regulator
FNV59_RS25440	COG1414	Transcriptional regulator
FNV59_RS25540	COG3903	Transcriptional regulator
FNV59_RS25540	COG3629	intracellular signal transduction
FNV59_RS25580	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FNV59_RS25600	COG2197	response regulator
FNV59_RS25605	COG4585	Histidine kinase
FNV59_RS25660	COG2843	Capsule synthesis protein
FNV59_RS25665	COG2197	response regulator
FNV59_RS25695	COG2197	response regulator
FNV59_RS25700	COG4585	Histidine kinase
FNV59_RS25725	COG0277	FAD linked oxidase domain protein
FNV59_RS25735	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FNV59_RS25745	COG2188	Transcriptional regulator
FNV59_RS25770	COG0386	Belongs to the glutathione peroxidase family
FNV59_RS25785	COG1686	Belongs to the peptidase S11 family
FNV59_RS25840	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FNV59_RS25860	COG1733	regulation of RNA biosynthetic process
FNV59_RS25870	COG4221	oxidoreductase activity
FNV59_RS25875	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS25880	COG2267	carboxylic ester hydrolase activity
FNV59_RS25910	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FNV59_RS25950	COG3903	Transcriptional regulator
FNV59_RS25950	COG3629	intracellular signal transduction
FNV59_RS25965	COG0318	PFAM AMP-dependent synthetase and ligase
FNV59_RS25980	COG1024	Enoyl-CoA hydratase
FNV59_RS25985	COG0515	serine threonine protein kinase
FNV59_RS25985	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FNV59_RS26005	COG1960	acyl-CoA dehydrogenase activity
FNV59_RS26015	COG2226	methyltransferase
FNV59_RS26020	COG0259	pyridoxamine-phosphate oxidase activity
FNV59_RS26025	COG0583	DNA-binding transcription factor activity
FNV59_RS26070	COG1024	Enoyl-CoA hydratase
FNV59_RS26075	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FNV59_RS26100	COG1960	acyl-CoA dehydrogenase activity
FNV59_RS26105	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS26125	COG1960	acyl-CoA dehydrogenase activity
FNV59_RS26130	COG1960	acyl-CoA dehydrogenase activity
FNV59_RS26140	COG0318	PFAM AMP-dependent synthetase and ligase
FNV59_RS26155	COG1595	DNA-templated transcription, initiation
FNV59_RS26205	COG2267	carboxylic ester hydrolase activity
FNV59_RS26215	COG4821	SIS domain
FNV59_RS26240	COG0259	pyridoxamine-phosphate oxidase activity
FNV59_RS26250	COG1024	Enoyl-CoA hydratase
FNV59_RS26255	COG0318	PFAM AMP-dependent synthetase and ligase
FNV59_RS26270	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FNV59_RS26305	COG1132	(ABC) transporter
FNV59_RS26310	COG0277	FAD linked oxidase domain protein
FNV59_RS26310	COG0247	lactate metabolic process
FNV59_RS26335	COG2124	cytochrome p450
FNV59_RS26345	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FNV59_RS26365	COG0789	Transcriptional regulator
FNV59_RS26375	COG0667	Aldo Keto reductase
FNV59_RS26390	COG1846	Transcriptional regulator
FNV59_RS26400	COG2252	PERMEase
FNV59_RS26410	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FNV59_RS26440	COG2814	Major facilitator Superfamily
FNV59_RS26450	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FNV59_RS26455	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FNV59_RS26460	COG1278	Cold shock
FNV59_RS26485	COG1061	Type III restriction enzyme res subunit
FNV59_RS26500	COG3973	AAA domain
FNV59_RS26505	COG3142	Participates in the control of copper homeostasis
FNV59_RS26540	COG1737	Transcriptional regulator
FNV59_RS26545	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FNV59_RS26550	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FNV59_RS26550	COG1263	PTS System
FNV59_RS26590	COG2084	Dehydrogenase
FNV59_RS26605	COG0459	protein refolding
FNV59_RS26625	COG0463	Glycosyl transferase, family 2
FNV59_RS26680	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FNV59_RS26695	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FNV59_RS26720	COG0308	aminopeptidase N
FNV59_RS26755	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNV59_RS26755	COG0723	plastoquinol--plastocyanin reductase activity
FNV59_RS26800	COG3842	ATPase activity
FNV59_RS26820	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FNV59_RS26825	COG0215	cysteine-tRNA ligase activity
FNV59_RS26830	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FNV59_RS26835	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FNV59_RS26840	COG1329	Transcriptional regulator
FNV59_RS26860	COG5002	protein histidine kinase activity
FNV59_RS26895	COG0588	phosphoglycerate mutase activity
FNV59_RS26925	COG0438	transferase activity, transferring glycosyl groups
FNV59_RS26960	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FNV59_RS26965	COG1090	epimerase
FNV59_RS26970	COG1595	DNA-templated transcription, initiation
FNV59_RS26980	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS26990	COG1309	transcriptional regulator
FNV59_RS26995	COG1063	alcohol dehydrogenase
FNV59_RS27020	COG2188	Transcriptional regulator
FNV59_RS27030	COG2188	Transcriptional regulator
FNV59_RS27040	COG4552	Acetyltransferase involved in intracellular survival and related
FNV59_RS27055	COG1490	D-aminoacyl-tRNA deacylase activity
FNV59_RS27060	COG0354	folic acid binding
FNV59_RS27070	COG3485	protocatechuate 3,4-dioxygenase
FNV59_RS27110	COG2897	thiosulfate sulfurtransferase activity
FNV59_RS27140	COG0745	RESPONSE REGULATOR receiver
FNV59_RS27145	COG1609	Transcriptional regulator
FNV59_RS27175	COG0745	RESPONSE REGULATOR receiver
FNV59_RS27180	COG1132	(ABC) transporter
FNV59_RS27185	COG0737	Belongs to the 5'-nucleotidase family
FNV59_RS27190	COG0456	acetyltransferase
FNV59_RS27205	COG1131	(ABC) transporter
FNV59_RS27220	COG1725	Transcriptional regulator
FNV59_RS27225	COG1131	(ABC) transporter
FNV59_RS27240	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FNV59_RS27250	COG0406	alpha-ribazole phosphatase activity
FNV59_RS27250	COG0494	nUDIX hydrolase
FNV59_RS27270	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FNV59_RS27280	COG0306	phosphate transporter
FNV59_RS27290	COG1937	Protein conserved in bacteria
FNV59_RS27305	COG0277	FAD linked oxidase domain protein
FNV59_RS27310	COG0671	phosphoesterase, PA-phosphatase related
FNV59_RS27315	COG0741	lytic transglycosylase activity
FNV59_RS27315	COG0739	heme binding
FNV59_RS27315	COG1196	nuclear chromosome segregation
FNV59_RS27425	COG1252	NADH dehydrogenase
FNV59_RS27435	COG1470	cell adhesion involved in biofilm formation
FNV59_RS27435	COG0366	Alpha amylase catalytic
FNV59_RS27455	COG0579	oxidoreductase
FNV59_RS27460	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FNV59_RS27470	COG0667	Aldo Keto reductase
FNV59_RS27495	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FNV59_RS27495	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FNV59_RS27505	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FNV59_RS27525	COG0513	Belongs to the DEAD box helicase family
FNV59_RS27565	COG1643	Atp-dependent helicase
FNV59_RS27600	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FNV59_RS27620	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FNV59_RS27625	COG0047	phosphoribosylformylglycinamidine synthase activity
FNV59_RS27630	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FNV59_RS27660	COG3850	Histidine kinase
FNV59_RS27665	COG2197	response regulator
FNV59_RS27675	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FNV59_RS27690	COG0151	Belongs to the GarS family
FNV59_RS27775	COG0433	COG0433 Predicted ATPase
FNV59_RS27790	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FNV59_RS27825	COG1191	sigma factor activity
FNV59_RS27830	COG1191	sigma factor activity
FNV59_RS27860	COG3467	pyridoxamine 5'-phosphate
FNV59_RS27870	COG0477	Major facilitator Superfamily
FNV59_RS27875	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FNV59_RS27885	COG2205	protein histidine kinase activity
FNV59_RS27890	COG0745	RESPONSE REGULATOR receiver
FNV59_RS27900	COG2329	Antibiotic biosynthesis monooxygenase
FNV59_RS27915	COG1846	Transcriptional regulator
FNV59_RS27960	COG0318	PFAM AMP-dependent synthetase and ligase
FNV59_RS27965	COG1595	DNA-templated transcription, initiation
FNV59_RS27980	COG1960	acyl-CoA dehydrogenase activity
FNV59_RS27990	COG1960	acyl-CoA dehydrogenase activity
FNV59_RS28020	COG2318	DinB family
FNV59_RS28055	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FNV59_RS28075	COG0653	protein targeting
FNV59_RS28095	COG0006	proline dipeptidase activity
FNV59_RS28110	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
FNV59_RS28130	COG2409	Drug exporters of the RND superfamily
FNV59_RS28135	COG4585	Histidine kinase
FNV59_RS28170	COG2837	iron assimilation
FNV59_RS28180	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FNV59_RS28185	COG0561	phosphatase activity
FNV59_RS28215	COG1131	(ABC) transporter
FNV59_RS28225	COG0789	Transcriptional regulator
FNV59_RS28230	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
FNV59_RS28240	COG0561	phosphatase activity
FNV59_RS28250	COG4988	ABC transporter
FNV59_RS28255	COG1294	oxidase, subunit
FNV59_RS28260	COG1271	oxidase subunit
FNV59_RS28265	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FNV59_RS28270	COG1609	Transcriptional regulator
FNV59_RS28290	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FNV59_RS28315	COG0662	Cupin 2, conserved barrel domain protein
FNV59_RS28320	COG1950	PFAM Membrane protein of
FNV59_RS28325	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FNV59_RS28330	COG0626	cystathionine gamma-synthase activity
FNV59_RS28365	COG2814	Major facilitator Superfamily
FNV59_RS28385	COG0305	Participates in initiation and elongation during chromosome replication
FNV59_RS28395	COG0359	binds to the 23S rRNA
FNV59_RS28400	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FNV59_RS28405	COG0629	single-stranded DNA binding
FNV59_RS28410	COG0360	Binds together with S18 to 16S ribosomal RNA
FNV59_RS28435	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FNV59_RS28460	COG0617	tRNA 3'-terminal CCA addition
FNV59_RS28480	COG1595	DNA-templated transcription, initiation
FNV59_RS28490	COG0492	ferredoxin-NADP+ reductase activity
FNV59_RS28495	COG3118	belongs to the thioredoxin family
FNV59_RS28510	COG1192	Involved in chromosome partitioning
FNV59_RS28515	COG0357	Ribosomal RNA small subunit methyltransferase G
FNV59_RS28525	COG0706	membrane insertase activity
FNV59_RS28530	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FNV59_RS28535	COG0594	ribonuclease P activity
FNV59_RS28540	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FNV59_RS28545	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FNV59_RS28555	COG0592	DNA-directed DNA polymerase activity
FNV59_RS28560	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FNV59_RS28565	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FNV59_RS28570	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
FNV59_RS28575	COG0187	DNA topoisomerase II activity
FNV59_RS28580	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FNV59_RS28615	COG0515	serine threonine protein kinase
FNV59_RS28640	COG0705	Rhomboid family
FNV59_RS28655	COG3764	Sortase (surface protein transpeptidase)
FNV59_RS28670	COG3764	Sortase (surface protein transpeptidase)
FNV59_RS28675	COG3764	Sortase (surface protein transpeptidase)
FNV59_RS28680	COG0515	serine threonine protein kinase
FNV59_RS28690	COG0768	penicillin binding
FNV59_RS28705	COG1716	ATPase activity
FNV59_RS28710	COG1716	ATPase activity
FNV59_RS28735	COG0745	RESPONSE REGULATOR receiver
FNV59_RS28750	COG4770	biotin carboxylase activity
FNV59_RS28765	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FNV59_RS28810	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FNV59_RS28840	COG0475	glutathione-regulated potassium exporter activity
FNV59_RS28850	COG1733	regulation of RNA biosynthetic process
FNV59_RS28855	COG0477	Major facilitator Superfamily
FNV59_RS28875	COG0277	FAD linked oxidase domain protein
FNV59_RS28890	COG0702	epimerase
FNV59_RS28895	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FNV59_RS28900	COG1733	regulation of RNA biosynthetic process
FNV59_RS28945	COG1250	3-hydroxyacyl-CoA dehydrogenase
FNV59_RS28950	COG1309	transcriptional regulator
FNV59_RS28955	COG1522	sequence-specific DNA binding
FNV59_RS28975	COG0746	molybdenum cofactor guanylyltransferase activity
FNV59_RS28990	COG0604	alcohol dehydrogenase
FNV59_RS28990	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS28990	COG3321	synthase
FNV59_RS29005	COG0515	serine threonine protein kinase
FNV59_RS29010	COG0515	serine threonine protein kinase
FNV59_RS29035	COG0022	dehydrogenase e1 component
FNV59_RS29040	COG0508	dehydrogenase complex catalyzes the overall conversion of
FNV59_RS29095	COG1362	aminopeptidase activity
FNV59_RS29100	COG1960	acyl-CoA dehydrogenase activity
FNV59_RS29110	COG1741	Belongs to the pirin family
FNV59_RS29125	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FNV59_RS29155	COG3866	Pectate lyase
FNV59_RS29165	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FNV59_RS29185	COG1289	transmembrane transporter activity
FNV59_RS29195	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FNV59_RS29200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FNV59_RS29230	COG2205	protein histidine kinase activity
FNV59_RS29235	COG0745	RESPONSE REGULATOR receiver
FNV59_RS29250	COG1653	transport
FNV59_RS29270	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FNV59_RS29280	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FNV59_RS29315	COG1278	Cold shock
FNV59_RS29350	COG0725	ABC transporter, periplasmic molybdate-binding protein
FNV59_RS29400	COG2815	serine threonine protein kinase
FNV59_RS29400	COG0515	serine threonine protein kinase
FNV59_RS29415	COG1595	DNA-templated transcription, initiation
FNV59_RS29425	COG0561	phosphatase activity
FNV59_RS29475	COG0745	RESPONSE REGULATOR receiver
FNV59_RS29480	COG5002	protein histidine kinase activity
FNV59_RS29490	COG2409	Drug exporters of the RND superfamily
FNV59_RS29495	COG4585	Histidine kinase
FNV59_RS29500	COG2197	response regulator
FNV59_RS29520	COG0640	Transcriptional regulator
FNV59_RS29525	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FNV59_RS29535	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FNV59_RS29605	COG2326	polyphosphate kinase activity
FNV59_RS29610	COG3387	PFAM Glycoside hydrolase 15-related
FNV59_RS29615	COG0477	Major facilitator Superfamily
FNV59_RS29685	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FNV59_RS29700	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FNV59_RS29700	COG0515	serine threonine protein kinase
FNV59_RS29725	COG1733	regulation of RNA biosynthetic process
FNV59_RS29750	COG2205	protein histidine kinase activity
FNV59_RS29755	COG0745	RESPONSE REGULATOR receiver
FNV59_RS29825	COG0717	Belongs to the dCTP deaminase family
FNV59_RS29850	COG0247	lactate metabolic process
FNV59_RS29850	COG2181	nitrate reductase activity
FNV59_RS29855	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FNV59_RS29860	COG0443	Heat shock 70 kDa protein
FNV59_RS29865	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FNV59_RS29870	COG0484	heat shock protein binding
FNV59_RS29875	COG0789	Transcriptional regulator
FNV59_RS29885	COG4213	ABC transporter substrate-binding protein
FNV59_RS29910	COG1305	Transglutaminase-like
FNV59_RS29955	COG0542	response to heat
FNV59_RS29985	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FNV59_RS30000	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FNV59_RS30005	COG0191	fructose-bisphosphate aldolase activity
FNV59_RS30025	COG3844	kynureninase activity
FNV59_RS30050	COG4585	Histidine kinase
FNV59_RS30055	COG2197	response regulator
FNV59_RS30065	COG2197	response regulator
FNV59_RS30080	COG3559	Exporter of polyketide antibiotics
FNV59_RS30085	COG1131	(ABC) transporter
FNV59_RS30100	COG4303	Ethanolamine ammonia lyase large subunit
FNV59_RS30120	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FNV59_RS30125	COG0737	Belongs to the 5'-nucleotidase family
FNV59_RS30135	COG1802	Transcriptional regulator
FNV59_RS30140	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FNV59_RS30145	COG0693	protein deglycase activity
FNV59_RS30165	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FNV59_RS30170	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FNV59_RS30205	COG5002	protein histidine kinase activity
FNV59_RS30205	COG5000	phosphorelay sensor kinase activity
FNV59_RS30285	COG0515	serine threonine protein kinase
FNV59_RS30330	COG4152	abc transporter atp-binding protein
FNV59_RS30390	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FNV59_RS30405	COG1132	(ABC) transporter
FNV59_RS30430	COG1408	metallophosphoesterase
FNV59_RS30455	COG0003	Pfam Anion-transporting ATPase
FNV59_RS30480	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNV59_RS30510	COG0596	Alpha beta hydrolase
FNV59_RS30520	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FNV59_RS30525	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FNV59_RS30530	COG0659	secondary active sulfate transmembrane transporter activity
FNV59_RS30590	COG1205	dead DEAH box helicase
FNV59_RS30590	COG1111	helicase
FNV59_RS30595	COG1366	Belongs to the anti-sigma-factor antagonist family
FNV59_RS30600	COG2172	sigma factor antagonist activity
FNV59_RS30605	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FNV59_RS30620	COG2815	serine threonine protein kinase
FNV59_RS30620	COG0515	serine threonine protein kinase
FNV59_RS30630	COG1754	DNA topoisomerase type I activity
FNV59_RS30630	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FNV59_RS30635	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FNV59_RS30640	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FNV59_RS30685	COG0017	Asparaginyl-tRNA synthetase
FNV59_RS30720	COG0105	UTP biosynthetic process
FNV59_RS30730	COG1051	belongs to the nudix hydrolase family
FNV59_RS30765	COG0174	glutamine synthetase
FNV59_RS30780	COG4106	trans-aconitate 2-methyltransferase activity
FNV59_RS30950	COG0305	Participates in initiation and elongation during chromosome replication
FNV59_RS31120	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FNV59_RS31120	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FNV59_RS31155	COG1136	(ABC) transporter
FNV59_RS31165	COG2197	response regulator
FNV59_RS31235	COG3629	intracellular signal transduction
FNV59_RS31235	COG3903	Transcriptional regulator
FNV59_RS31240	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FNV59_RS31240	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FNV59_RS31265	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FNV59_RS31270	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FNV59_RS31275	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FNV59_RS31280	COG0254	rRNA binding
FNV59_RS31290	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FNV59_RS31310	COG1012	belongs to the aldehyde dehydrogenase family
FNV59_RS31330	COG0076	glutamate decarboxylase activity
FNV59_RS31340	COG0789	Transcriptional regulator
FNV59_RS31345	COG0393	Putative heavy-metal-binding
FNV59_RS31360	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FNV59_RS31365	COG2027	D-alanyl-D-alanine carboxypeptidase
FNV59_RS31375	COG0037	tRNA processing
FNV59_RS31390	COG0302	gtp cyclohydrolase
FNV59_RS31405	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FNV59_RS31420	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FNV59_RS31420	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FNV59_RS31445	COG0649	NAD binding
FNV59_RS31465	COG2197	response regulator
FNV59_RS31470	COG1660	Displays ATPase and GTPase activities
FNV59_RS31495	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FNV59_RS31500	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FNV59_RS31510	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FNV59_RS31530	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FNV59_RS31560	COG0739	heme binding
FNV59_RS31575	COG2205	protein histidine kinase activity
FNV59_RS31580	COG0745	RESPONSE REGULATOR receiver
FNV59_RS31590	COG1595	DNA-templated transcription, initiation
FNV59_RS31605	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
FNV59_RS31625	COG0248	Ppx GppA phosphatase
FNV59_RS31630	COG1082	Xylose isomerase domain protein TIM barrel
FNV59_RS31635	COG1309	transcriptional regulator
FNV59_RS31640	COG0129	dihydroxy-acid dehydratase activity
FNV59_RS31645	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FNV59_RS31645	COG0515	serine threonine protein kinase
FNV59_RS31655	COG4991	sh3 domain protein
FNV59_RS31665	COG2226	methyltransferase
FNV59_RS31675	COG0842	Transport permease protein
FNV59_RS31675	COG1129	ABC transporter
FNV59_RS31685	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FNV59_RS31690	COG0180	Tryptophanyl-tRNA synthetase
FNV59_RS31730	COG0123	including yeast histone deacetylase and acetoin utilization protein
FNV59_RS31785	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FNV59_RS31790	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FNV59_RS31795	COG0181	hydroxymethylbilane synthase activity
FNV59_RS31800	COG1648	precorrin-2 dehydrogenase activity
FNV59_RS31800	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FNV59_RS31805	COG0113	porphobilinogen synthase activity
FNV59_RS31835	COG0018	arginyl-trna synthetase
FNV59_RS31840	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
FNV59_RS31860	COG1690	Belongs to the RtcB family
FNV59_RS31880	COG1742	UPF0060 membrane protein
FNV59_RS31890	COG1846	Transcriptional regulator
FNV59_RS31895	COG1733	regulation of RNA biosynthetic process
FNV59_RS31910	COG0583	DNA-binding transcription factor activity
FNV59_RS31925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV59_RS31955	COG0531	amino acid
FNV59_RS31965	COG1136	(ABC) transporter
FNV59_RS31975	COG2197	response regulator
FNV59_RS31995	COG0501	Belongs to the peptidase M48B family
FNV59_RS32005	COG1968	undecaprenyl-diphosphatase activity
FNV59_RS32030	COG0531	amino acid
FNV59_RS32050	COG0598	Magnesium transport protein CorA
FNV59_RS32055	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FNV59_RS32070	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FNV59_RS32075	COG0406	alpha-ribazole phosphatase activity
FNV59_RS32095	COG1333	cytochrome c biogenesis protein
FNV59_RS32100	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FNV59_RS32145	COG2226	methyltransferase
FNV59_RS32150	COG3321	synthase
FNV59_RS32150	COG0604	alcohol dehydrogenase
FNV59_RS32150	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS32155	COG0640	Transcriptional regulator
FNV59_RS32175	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FNV59_RS32180	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FNV59_RS32185	COG0163	prenyltransferase activity
FNV59_RS32195	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FNV59_RS32210	COG1309	transcriptional regulator
FNV59_RS32225	COG0183	Belongs to the thiolase family
FNV59_RS32235	COG1278	Cold shock
FNV59_RS32240	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FNV59_RS32255	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FNV59_RS32285	COG2226	methyltransferase
FNV59_RS32315	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FNV59_RS32320	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FNV59_RS32325	COG0649	NAD binding
FNV59_RS32335	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FNV59_RS32340	COG1034	ATP synthesis coupled electron transport
FNV59_RS32345	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FNV59_RS32350	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FNV59_RS32360	COG0713	ATP synthesis coupled electron transport
FNV59_RS32365	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FNV59_RS32375	COG1007	ATP synthesis coupled electron transport
FNV59_RS32380	COG0514	ATP-dependent DNA helicase (RecQ)
FNV59_RS32405	COG0492	ferredoxin-NADP+ reductase activity
FNV59_RS32415	COG5280	Phage tail tape measure protein TP901
FNV59_RS32415	COG3953	SLT domain
FNV59_RS32425	COG0596	Alpha beta hydrolase
FNV59_RS32425	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FNV59_RS32430	COG0142	geranyltranstransferase activity
FNV59_RS32445	COG1131	(ABC) transporter
FNV59_RS32455	COG0655	NAD(P)H dehydrogenase (quinone) activity
FNV59_RS32480	COG0702	epimerase
FNV59_RS32485	COG1733	regulation of RNA biosynthetic process
FNV59_RS32490	COG1013	pyruvate-flavodoxin oxidoreductase activity
FNV59_RS32495	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FNV59_RS32495	COG0674	pyruvate-flavodoxin oxidoreductase activity
FNV59_RS32515	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FNV59_RS32520	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FNV59_RS32525	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FNV59_RS32530	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FNV59_RS32535	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FNV59_RS32540	COG0839	Belongs to the complex I subunit 6 family
FNV59_RS32545	COG0713	ATP synthesis coupled electron transport
FNV59_RS32560	COG1007	ATP synthesis coupled electron transport
FNV59_RS32565	COG0501	Belongs to the peptidase M48B family
FNV59_RS32570	COG3304	Inner membrane component domain
FNV59_RS32590	COG2261	transglycosylase associated protein
FNV59_RS32595	COG1666	GTP binding
FNV59_RS32610	COG0702	epimerase
FNV59_RS32615	COG0402	S-adenosylhomocysteine deaminase activity
FNV59_RS32635	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FNV59_RS32640	COG2030	dehydratase
FNV59_RS32655	COG0477	Major facilitator Superfamily
FNV59_RS32660	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FNV59_RS32665	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FNV59_RS32680	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FNV59_RS32685	COG0436	Aminotransferase
FNV59_RS32705	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FNV59_RS32710	COG0081	regulation of translation
FNV59_RS32725	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FNV59_RS32730	COG0222	ribosome binding
FNV59_RS32740	COG0085	RNA polymerase activity
FNV59_RS32745	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FNV59_RS32775	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FNV59_RS32780	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FNV59_RS32785	COG0049	tRNA binding
FNV59_RS32790	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FNV59_RS32795	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FNV59_RS32810	COG2124	cytochrome p450
FNV59_RS32830	COG1404	Belongs to the peptidase S8 family
FNV59_RS32855	COG0051	transcription antitermination factor activity, RNA binding
FNV59_RS32860	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FNV59_RS32865	COG0088	Forms part of the polypeptide exit tunnel
FNV59_RS32870	COG0089	rRNA binding
FNV59_RS32875	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FNV59_RS32880	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FNV59_RS32885	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FNV59_RS32890	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FNV59_RS32895	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FNV59_RS32900	COG0255	Belongs to the universal ribosomal protein uL29 family
FNV59_RS32905	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FNV59_RS32910	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FNV59_RS32915	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FNV59_RS32920	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FNV59_RS32925	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FNV59_RS32935	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FNV59_RS32940	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FNV59_RS32945	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FNV59_RS32950	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FNV59_RS32955	COG1841	ribosomal large subunit assembly
FNV59_RS32960	COG0200	Binds to the 23S rRNA
FNV59_RS32970	COG0563	adenylate kinase activity
FNV59_RS32980	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FNV59_RS32985	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FNV59_RS32990	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FNV59_RS32995	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FNV59_RS33000	COG0202	RNA polymerase activity
FNV59_RS33005	COG0203	ribosomal protein L17
FNV59_RS33010	COG0101	tRNA pseudouridine synthase activity
FNV59_RS33020	COG1215	transferase activity, transferring glycosyl groups
FNV59_RS33025	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FNV59_RS33025	COG4124	Belongs to the glycosyl hydrolase 26 family
FNV59_RS33040	COG0463	Glycosyl transferase, family 2
FNV59_RS33050	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FNV59_RS33055	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FNV59_RS33060	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FNV59_RS33065	COG1072	(Pantothenic acid kinase))
FNV59_RS33070	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FNV59_RS33115	COG0736	holo-[acyl-carrier-protein] synthase activity
FNV59_RS33130	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FNV59_RS33140	COG0802	atpase or kinase
FNV59_RS33160	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FNV59_RS33170	COG1609	Transcriptional regulator
FNV59_RS33180	COG1175	transmembrane transport
FNV59_RS33185	COG0395	ABC-type sugar transport system, permease component
FNV59_RS33190	COG1472	Belongs to the glycosyl hydrolase 3 family
FNV59_RS33195	COG1609	Transcriptional regulator
FNV59_RS33220	COG4941	Belongs to the sigma-70 factor family
FNV59_RS33230	COG0726	polysaccharide deacetylase
FNV59_RS33235	COG0726	polysaccharide deacetylase
FNV59_RS33240	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FNV59_RS33245	COG0459	protein refolding
FNV59_RS33255	COG4221	oxidoreductase activity
FNV59_RS33265	COG0583	DNA-binding transcription factor activity
FNV59_RS33280	COG1595	DNA-templated transcription, initiation
FNV59_RS33290	COG0516	GMP reductase activity
FNV59_RS33305	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FNV59_RS33325	COG0515	serine threonine protein kinase
FNV59_RS33330	COG2815	serine threonine protein kinase
FNV59_RS33330	COG0515	serine threonine protein kinase
FNV59_RS33335	COG0515	serine threonine protein kinase
FNV59_RS33340	COG1012	belongs to the aldehyde dehydrogenase family
FNV59_RS33365	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FNV59_RS33365	COG0519	Catalyzes the synthesis of GMP from XMP
FNV59_RS33410	COG2197	response regulator
FNV59_RS33445	COG0739	heme binding
FNV59_RS33455	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FNV59_RS33455	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FNV59_RS33470	COG0714	Associated with various cellular activities
FNV59_RS33475	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FNV59_RS33480	COG3552	Protein containing von Willebrand factor type A (VWA) domain
FNV59_RS33500	COG0045	succinate-CoA ligase (ADP-forming) activity
FNV59_RS33535	COG0138	bifunctional purine biosynthesis protein purh
FNV59_RS33555	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FNV59_RS33575	COG0039	L-malate dehydrogenase activity
FNV59_RS33595	COG0456	acetyltransferase
FNV59_RS33595	COG1846	Transcriptional regulator
FNV59_RS33600	COG1012	belongs to the aldehyde dehydrogenase family
FNV59_RS33610	COG4175	Glycine betaine
FNV59_RS33610	COG0517	IMP dehydrogenase activity
FNV59_RS33615	COG4176	ABC-type proline glycine betaine transport system permease component
FNV59_RS33630	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FNV59_RS33635	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FNV59_RS33645	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FNV59_RS33655	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FNV59_RS33665	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FNV59_RS33670	COG0512	Glutamine amidotransferase of anthranilate synthase
FNV59_RS33670	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FNV59_RS33675	COG3224	Antibiotic biosynthesis monooxygenase
FNV59_RS33695	COG0754	glutathionylspermidine amidase activity
FNV59_RS33700	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FNV59_RS33705	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FNV59_RS33715	COG0180	Tryptophanyl-tRNA synthetase
FNV59_RS33750	COG1295	ribonuclease BN
FNV59_RS33755	COG1686	Belongs to the peptidase S11 family
FNV59_RS33765	COG1408	metallophosphoesterase
FNV59_RS33785	COG2205	protein histidine kinase activity
FNV59_RS33790	COG0745	RESPONSE REGULATOR receiver
FNV59_RS33795	COG2409	Drug exporters of the RND superfamily
FNV59_RS33840	COG1053	succinate dehydrogenase
FNV59_RS33850	COG2009	succinate dehydrogenase
FNV59_RS33860	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FNV59_RS33890	COG1595	DNA-templated transcription, initiation
FNV59_RS33895	COG1595	DNA-templated transcription, initiation
FNV59_RS33910	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FNV59_RS33910	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FNV59_RS33925	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FNV59_RS33935	COG1216	Glycosyl transferase, family 2
FNV59_RS33950	COG2089	acid synthase
FNV59_RS33965	COG0573	inorganic phosphate transmembrane transporter activity
FNV59_RS34000	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FNV59_RS34005	COG4195	phage-related replication protein
FNV59_RS34060	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FNV59_RS34060	COG1473	amidohydrolase
FNV59_RS34070	COG1744	ABC transporter substrate-binding protein PnrA-like
FNV59_RS34075	COG1744	ABC transporter substrate-binding protein PnrA-like
FNV59_RS34080	COG3845	ABC transporter
FNV59_RS34085	COG4603	Belongs to the binding-protein-dependent transport system permease family
FNV59_RS34090	COG1079	Belongs to the binding-protein-dependent transport system permease family
FNV59_RS34120	COG0592	DNA-directed DNA polymerase activity
FNV59_RS34125	COG2814	Major facilitator Superfamily
FNV59_RS34130	COG0583	DNA-binding transcription factor activity
FNV59_RS34140	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FNV59_RS34165	COG2205	protein histidine kinase activity
FNV59_RS34170	COG0745	RESPONSE REGULATOR receiver
FNV59_RS34175	COG1595	DNA-templated transcription, initiation
FNV59_RS34190	COG1012	belongs to the aldehyde dehydrogenase family
FNV59_RS34195	COG1012	belongs to the aldehyde dehydrogenase family
FNV59_RS34255	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FNV59_RS34270	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FNV59_RS34300	COG4770	biotin carboxylase activity
FNV59_RS34310	COG0424	maF-like protein
FNV59_RS34325	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FNV59_RS34335	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FNV59_RS34345	COG1024	Enoyl-CoA hydratase
FNV59_RS34355	COG2986	histidine ammonia-lyase
FNV59_RS34360	COG1278	Cold shock
FNV59_RS34400	COG1136	(ABC) transporter
FNV59_RS34410	COG1404	Belongs to the peptidase S8 family
FNV59_RS34425	COG1064	alcohol dehydrogenase
FNV59_RS34430	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FNV59_RS34435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FNV59_RS34445	COG2132	Multicopper oxidase
FNV59_RS34485	COG3173	Aminoglycoside phosphotransferase
FNV59_RS34510	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FNV59_RS34535	COG2255	four-way junction helicase activity
FNV59_RS34540	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FNV59_RS34585	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FNV59_RS34595	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FNV59_RS34620	COG1331	Highly conserved protein containing a thioredoxin domain
FNV59_RS34650	COG1309	transcriptional regulator
FNV59_RS34655	COG0477	Major facilitator Superfamily
FNV59_RS34665	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
FNV59_RS34770	COG0436	Aminotransferase
FNV59_RS34785	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FNV59_RS34800	COG1414	Transcriptional regulator
FNV59_RS34805	COG0251	oxidation-reduction process
FNV59_RS34810	COG2610	gluconate transmembrane transporter activity
FNV59_RS34880	COG2894	cell division
FNV59_RS34910	COG2197	response regulator
FNV59_RS34930	COG2885	chlorophyll binding
FNV59_RS34935	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FNV59_RS34965	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FNV59_RS34975	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FNV59_RS34990	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FNV59_RS34995	COG0450	alkyl hydroperoxide reductase
FNV59_RS35010	COG1136	(ABC) transporter
FNV59_RS35030	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FNV59_RS35060	COG0114	fumarate hydratase activity
FNV59_RS35080	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FNV59_RS35080	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FNV59_RS35105	COG0778	Nitroreductase
FNV59_RS35110	COG1722	exodeoxyribonuclease VII activity
FNV59_RS35115	COG1570	exodeoxyribonuclease VII activity
FNV59_RS35125	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FNV59_RS35140	COG0012	GTP binding
FNV59_RS35230	COG1053	succinate dehydrogenase
FNV59_RS35250	COG1217	gtp-binding protein TYPA
FNV59_RS35265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNV59_RS35270	COG0444	Belongs to the ABC transporter superfamily
FNV59_RS35275	COG4608	Belongs to the ABC transporter superfamily
FNV59_RS35280	COG0346	lactoylglutathione lyase activity
FNV59_RS35290	COG0601	transmembrane transport
FNV59_RS35295	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNV59_RS35300	COG0444	Belongs to the ABC transporter superfamily
FNV59_RS35305	COG4608	Belongs to the ABC transporter superfamily
FNV59_RS35320	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FNV59_RS35340	COG1131	(ABC) transporter
FNV59_RS35350	COG4585	Histidine kinase
FNV59_RS35355	COG2197	response regulator
FNV59_RS35390	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FNV59_RS35400	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FNV59_RS35410	COG0519	Catalyzes the synthesis of GMP from XMP
FNV59_RS35415	COG1024	Enoyl-CoA hydratase
FNV59_RS35430	COG1595	DNA-templated transcription, initiation
FNV59_RS35440	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FNV59_RS35445	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FNV59_RS35470	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FNV59_RS35480	COG0598	Magnesium transport protein CorA
FNV59_RS35490	COG2814	Major facilitator Superfamily
FNV59_RS35505	COG2095	MarC family integral membrane protein
FNV59_RS35515	COG1432	Conserved Protein
FNV59_RS35520	COG0596	Alpha beta hydrolase
FNV59_RS35565	COG0747	negative chemotaxis
FNV59_RS35570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNV59_RS35575	COG0601	transmembrane transport
FNV59_RS35635	COG0210	DNA helicase
FNV59_RS35640	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FNV59_RS35680	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FNV59_RS35735	COG3480	Lon protease (S16) C-terminal proteolytic domain
FNV59_RS35745	COG1615	UPF0182 protein
FNV59_RS35770	COG0753	catalase activity
FNV59_RS35775	COG0517	IMP dehydrogenase activity
FNV59_RS35775	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FNV59_RS35780	COG0483	inositol monophosphate 1-phosphatase activity
FNV59_RS35800	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FNV59_RS35810	COG2135	peptidase activity
FNV59_RS35820	COG1595	DNA-templated transcription, initiation
FNV59_RS35825	COG5662	AntiSigma factor
FNV59_RS35830	COG2199	diguanylate cyclase activity
FNV59_RS35830	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FNV59_RS35845	COG0242	peptide deformylase activity
FNV59_RS35855	COG2124	cytochrome p450
FNV59_RS35875	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FNV59_RS35900	COG2188	Transcriptional regulator
FNV59_RS35905	COG2182	Extracellular solute-binding protein
FNV59_RS35910	COG1175	transmembrane transport
FNV59_RS35915	COG0395	ABC-type sugar transport system, permease component
FNV59_RS35920	COG1472	Belongs to the glycosyl hydrolase 3 family
FNV59_RS35925	COG0363	glucosamine-6-phosphate deaminase activity
FNV59_RS35930	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FNV59_RS35945	COG1597	lipid kinase activity
FNV59_RS35990	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FNV59_RS35995	COG0142	geranyltranstransferase activity
FNV59_RS36065	COG4106	trans-aconitate 2-methyltransferase activity
FNV59_RS36070	COG1126	abc transporter atp-binding protein
FNV59_RS36090	COG0281	malic enzyme
FNV59_RS36095	COG0604	alcohol dehydrogenase
FNV59_RS36130	COG0567	Dehydrogenase, E1 component
FNV59_RS36130	COG0508	dehydrogenase complex catalyzes the overall conversion of
FNV59_RS36135	COG2205	protein histidine kinase activity
FNV59_RS36140	COG0745	RESPONSE REGULATOR receiver
FNV59_RS36165	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FNV59_RS36250	COG0701	Predicted permease
FNV59_RS36255	COG0768	penicillin binding
FNV59_RS36260	COG0772	Belongs to the SEDS family
FNV59_RS36270	COG2205	protein histidine kinase activity
FNV59_RS36295	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FNV59_RS36305	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FNV59_RS36370	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FNV59_RS36405	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FNV59_RS36445	COG1674	ftsk spoiiie
FNV59_RS36515	COG0018	arginyl-trna synthetase
FNV59_RS36520	COG0019	diaminopimelate decarboxylase activity
FNV59_RS36525	COG0460	homoserine dehydrogenase
FNV59_RS36530	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FNV59_RS36535	COG0083	homoserine kinase activity
FNV59_RS36550	COG1316	TRANSCRIPTIONal
FNV59_RS36555	COG0254	rRNA binding
FNV59_RS36560	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FNV59_RS36565	COG2890	protein-(glutamine-N5) methyltransferase activity
FNV59_RS36575	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FNV59_RS36585	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FNV59_RS36590	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FNV59_RS36605	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FNV59_RS36610	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FNV59_RS36615	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FNV59_RS36620	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FNV59_RS36625	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FNV59_RS36630	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FNV59_RS36635	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FNV59_RS36650	COG2197	response regulator
FNV59_RS36675	COG1250	3-hydroxyacyl-CoA dehydrogenase
FNV59_RS36695	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
FNV59_RS36740	COG1131	(ABC) transporter
FNV59_RS36760	COG0183	Belongs to the thiolase family
FNV59_RS36795	COG2814	Major facilitator Superfamily
FNV59_RS36840	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FNV59_RS36840	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FNV59_RS36880	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FNV59_RS36885	COG0857	belongs to the CobB CobQ family
FNV59_RS36885	COG0280	phosphate acetyltransferase
FNV59_RS36890	COG0205	6-phosphofructokinase activity
FNV59_RS36905	COG0395	ABC-type sugar transport system, permease component
FNV59_RS36910	COG1175	transmembrane transport
FNV59_RS36935	COG4565	transcriptional regulatory protein
FNV59_RS36940	COG3290	protein histidine kinase activity
FNV59_RS36945	COG1301	dicarboxylic acid transport
FNV59_RS36955	COG0477	Major facilitator Superfamily
FNV59_RS36970	COG1522	sequence-specific DNA binding
FNV59_RS36990	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FNV59_RS36995	COG3281	Trehalose synthase
FNV59_RS37005	COG0366	Alpha amylase catalytic
FNV59_RS37015	COG0058	SHG alpha-glucan phosphorylase activity
FNV59_RS37035	COG1132	(ABC) transporter
FNV59_RS37040	COG1132	(ABC) transporter
FNV59_RS37045	COG1132	(ABC) transporter
FNV59_RS37050	COG1132	(ABC) transporter
FNV59_RS37055	COG1131	(ABC) transporter
FNV59_RS37065	COG4585	Histidine kinase
FNV59_RS37070	COG2197	response regulator
FNV59_RS37080	COG1376	ErfK ybiS ycfS ynhG family protein
FNV59_RS37085	COG1376	ErfK ybiS ycfS ynhG family protein
FNV59_RS37130	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FNV59_RS37150	COG0475	glutathione-regulated potassium exporter activity
FNV59_RS37155	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FNV59_RS37170	COG3629	intracellular signal transduction
FNV59_RS37170	COG3903	Transcriptional regulator
FNV59_RS37195	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FNV59_RS37225	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FNV59_RS37230	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FNV59_RS37235	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FNV59_RS37240	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FNV59_RS37250	COG4122	O-methyltransferase activity
FNV59_RS37255	COG1233	COG1233 Phytoene dehydrogenase and related
FNV59_RS37285	COG3251	PFAM MbtH domain protein
FNV59_RS37290	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FNV59_RS37290	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FNV59_RS37300	COG0277	FAD linked oxidase domain protein
FNV59_RS37315	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FNV59_RS37320	COG1760	l-serine dehydratase
FNV59_RS37325	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FNV59_RS37330	COG0509	glycine decarboxylation via glycine cleavage system
FNV59_RS37335	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FNV59_RS37355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNV59_RS37370	COG0444	Belongs to the ABC transporter superfamily
FNV59_RS37375	COG4608	Belongs to the ABC transporter superfamily
FNV59_RS37390	COG2860	membrane
FNV59_RS37410	COG2378	regulation of single-species biofilm formation
FNV59_RS37420	COG1309	transcriptional regulator
FNV59_RS37455	COG0482	sulfurtransferase activity
FNV59_RS37465	COG1611	Belongs to the LOG family
FNV59_RS37470	COG4221	oxidoreductase activity
FNV59_RS37480	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FNV59_RS37490	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FNV59_RS37495	COG0154	amidase activity
FNV59_RS37505	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FNV59_RS37510	COG2409	Drug exporters of the RND superfamily
FNV59_RS37515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FNV59_RS37530	COG2197	response regulator
FNV59_RS37540	COG2133	pyrroloquinoline quinone binding
FNV59_RS37545	COG0667	Aldo Keto reductase
FNV59_RS37555	COG5001	Diguanylate cyclase
FNV59_RS37565	COG0440	acetolactate synthase activity
FNV59_RS37570	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FNV59_RS37580	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FNV59_RS37580	COG1672	PFAM Archaeal ATPase
FNV59_RS37585	COG0477	Major facilitator Superfamily
FNV59_RS37605	COG3214	Protein conserved in bacteria
FNV59_RS37615	COG0506	proline dehydrogenase activity
FNV59_RS37620	COG1012	belongs to the aldehyde dehydrogenase family
FNV59_RS37635	COG1082	Xylose isomerase domain protein TIM barrel
FNV59_RS37645	COG0477	Major facilitator Superfamily
FNV59_RS37660	COG0473	3-isopropylmalate dehydrogenase activity
FNV59_RS37665	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FNV59_RS37685	COG0832	Belongs to the urease beta subunit family
FNV59_RS37685	COG0831	urea catabolic process
FNV59_RS37690	COG0804	urea catabolic process
FNV59_RS37695	COG2957	Belongs to the agmatine deiminase family
FNV59_RS37705	COG0477	Major facilitator Superfamily
FNV59_RS37710	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FNV59_RS37735	COG2197	response regulator
FNV59_RS37745	COG1131	(ABC) transporter
FNV59_RS37780	COG4585	Histidine kinase
FNV59_RS37790	COG2353	YceI-like domain
FNV59_RS37795	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FNV59_RS37815	COG2018	Roadblock/LC7 domain
FNV59_RS37835	COG2018	Roadblock/LC7 domain
FNV59_RS37840	COG5002	protein histidine kinase activity
FNV59_RS37850	COG0179	Fumarylacetoacetate (FAA) hydrolase
FNV59_RS37855	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FNV59_RS37905	COG1414	Transcriptional regulator
FNV59_RS37910	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FNV59_RS37915	COG0066	3-isopropylmalate dehydratase activity
FNV59_RS37925	COG0776	regulation of translation
FNV59_RS37935	COG1920	GTP binding
FNV59_RS37945	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FNV59_RS37950	COG1181	Belongs to the D-alanine--D-alanine ligase family
FNV59_RS37975	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FNV59_RS37980	COG1461	Dihydroxyacetone kinase
FNV59_RS37990	COG0326	Molecular chaperone. Has ATPase activity
FNV59_RS38000	COG0742	ribosomal rna small subunit methyltransferase
FNV59_RS38005	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FNV59_RS38020	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FNV59_RS38025	COG0571	ribonuclease III activity
FNV59_RS38030	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FNV59_RS38035	COG1733	regulation of RNA biosynthetic process
FNV59_RS38050	COG0515	serine threonine protein kinase
FNV59_RS38050	COG2815	serine threonine protein kinase
FNV59_RS38070	COG2340	Cysteine-rich secretory protein family
FNV59_RS38075	COG1254	Belongs to the acylphosphatase family
FNV59_RS38090	COG0477	Major facilitator Superfamily
FNV59_RS38130	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FNV59_RS38140	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FNV59_RS38150	COG0442	prolyl-tRNA aminoacylation
FNV59_RS38160	COG0228	four-way junction DNA binding
FNV59_RS38165	COG1837	Belongs to the UPF0109 family
FNV59_RS38170	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FNV59_RS38175	COG0336	Belongs to the RNA methyltransferase TrmD family
FNV59_RS38180	COG0335	large ribosomal subunit rRNA binding
FNV59_RS38190	COG0681	Belongs to the peptidase S26 family
FNV59_RS38205	COG0494	nUDIX hydrolase
FNV59_RS38215	COG0792	nuclease activity
FNV59_RS38230	COG1191	sigma factor activity
FNV59_RS38245	COG0052	Belongs to the universal ribosomal protein uS2 family
FNV59_RS38250	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FNV59_RS38255	COG0528	UMP kinase activity
FNV59_RS38260	COG0233	cytoplasmic translational termination
FNV59_RS38265	COG0575	Belongs to the CDS family
FNV59_RS38275	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FNV59_RS38285	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FNV59_RS38290	COG3842	ATPase activity
FNV59_RS38320	COG1136	(ABC) transporter
FNV59_RS38325	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FNV59_RS38335	COG1012	belongs to the aldehyde dehydrogenase family
FNV59_RS38375	COG0477	Major facilitator Superfamily
FNV59_RS38380	COG2226	methyltransferase
FNV59_RS38400	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FNV59_RS38425	COG3842	ATPase activity
FNV59_RS38430	COG1176	ABC-type spermidine putrescine transport system, permease component I
FNV59_RS38435	COG1177	transmembrane transport
FNV59_RS38440	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNV59_RS38470	COG2508	Transcriptional regulator
FNV59_RS38470	COG2508	Transcriptional regulator
FNV59_RS38475	COG1012	belongs to the aldehyde dehydrogenase family
FNV59_RS38480	COG1472	Belongs to the glycosyl hydrolase 3 family
FNV59_RS38485	COG1653	transport
FNV59_RS38490	COG4209	transmembrane transport
FNV59_RS38495	COG0395	ABC-type sugar transport system, permease component
FNV59_RS38535	COG5297	Belongs to the glycosyl hydrolase family 6
FNV59_RS38550	COG0653	protein targeting
FNV59_RS38560	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FNV59_RS38565	COG0750	zinc metalloprotease
FNV59_RS38570	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FNV59_RS38585	COG0442	prolyl-tRNA aminoacylation
FNV59_RS38605	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FNV59_RS38630	COG0779	Required for maturation of 30S ribosomal subunits
FNV59_RS38645	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FNV59_RS38655	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FNV59_RS38660	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FNV59_RS38685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNV59_RS38690	COG0601	transmembrane transport
FNV59_RS38700	COG0455	bacterial-type flagellum organization
FNV59_RS38720	COG1404	Belongs to the peptidase S8 family
FNV59_RS38795	COG1674	ftsk spoiiie
FNV59_RS38810	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FNV59_RS38815	COG1185	polyribonucleotide nucleotidyltransferase activity
FNV59_RS38820	COG0612	Peptidase, M16
FNV59_RS38825	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FNV59_RS38845	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
FNV59_RS38850	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FNV59_RS38855	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FNV59_RS38890	COG2208	phosphoserine phosphatase activity
FNV59_RS38890	COG2770	Histidine kinase
FNV59_RS38910	COG1674	ftsk spoiiie
FNV59_RS38920	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FNV59_RS38930	COG1058	Belongs to the CinA family
FNV59_RS38930	COG1546	Belongs to the CinA family
FNV59_RS38935	COG1396	sequence-specific DNA binding
FNV59_RS38940	COG0783	Belongs to the Dps family
FNV59_RS38950	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS38955	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FNV59_RS38960	COG1201	RNA secondary structure unwinding
FNV59_RS38990	COG0628	permease
FNV59_RS39000	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FNV59_RS39020	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FNV59_RS39030	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FNV59_RS39035	COG0765	amino acid transport
FNV59_RS39040	COG0765	amino acid transport
FNV59_RS39045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNV59_RS39050	COG1126	abc transporter atp-binding protein
FNV59_RS39055	COG0745	RESPONSE REGULATOR receiver
FNV59_RS39060	COG2205	protein histidine kinase activity
FNV59_RS39090	COG2197	response regulator
FNV59_RS39120	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FNV59_RS39140	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FNV59_RS39150	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FNV59_RS39155	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FNV59_RS39165	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FNV59_RS39205	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FNV59_RS39210	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FNV59_RS39215	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FNV59_RS39250	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FNV59_RS39290	COG1802	Transcriptional regulator
FNV59_RS39295	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FNV59_RS39310	COG0187	DNA topoisomerase II activity
FNV59_RS39330	COG2197	response regulator
FNV59_RS39340	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FNV59_RS39345	COG4565	transcriptional regulatory protein
FNV59_RS39355	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNV59_RS39365	COG4565	transcriptional regulatory protein
FNV59_RS39370	COG3290	protein histidine kinase activity
FNV59_RS39385	COG0372	Belongs to the citrate synthase family
FNV59_RS39405	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FNV59_RS39410	COG0612	Peptidase, M16
FNV59_RS39425	COG1802	Transcriptional regulator
FNV59_RS39430	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FNV59_RS39440	COG1042	CoA-binding domain protein
FNV59_RS39440	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FNV59_RS39440	COG0045	succinate-CoA ligase (ADP-forming) activity
FNV59_RS39455	COG1435	thymidine kinase activity
FNV59_RS39495	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FNV59_RS39505	COG0745	RESPONSE REGULATOR receiver
FNV59_RS39510	COG2205	protein histidine kinase activity
FNV59_RS39535	COG0756	dUTP diphosphatase activity
FNV59_RS39550	COG1136	(ABC) transporter
FNV59_RS39580	COG0569	domain protein
FNV59_RS39585	COG0531	amino acid
FNV59_RS39590	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FNV59_RS39620	COG2255	four-way junction helicase activity
FNV59_RS39650	COG4585	Histidine kinase
FNV59_RS39655	COG2409	Drug exporters of the RND superfamily
FNV59_RS39670	COG0243	molybdopterin cofactor binding
FNV59_RS39675	COG1799	cell septum assembly
FNV59_RS39705	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FNV59_RS39720	COG2235	arginine
FNV59_RS39725	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FNV59_RS39730	COG0531	amino acid
FNV59_RS39740	COG1024	Enoyl-CoA hydratase
FNV59_RS39780	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FNV59_RS39800	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FNV59_RS39810	COG1404	Belongs to the peptidase S8 family
FNV59_RS39815	COG0745	RESPONSE REGULATOR receiver
FNV59_RS39820	COG2205	protein histidine kinase activity
FNV59_RS39835	COG3537	Alpha-1,2-mannosidase
FNV59_RS39845	COG1653	transport
FNV59_RS39850	COG1175	transmembrane transport
FNV59_RS39855	COG0395	ABC-type sugar transport system, permease component
FNV59_RS39860	COG1940	carbohydrate kinase activity
FNV59_RS39865	COG4213	ABC transporter substrate-binding protein
FNV59_RS39875	COG4214	carbohydrate transport
FNV59_RS39880	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FNV59_RS39885	COG0531	amino acid
FNV59_RS39905	COG1250	3-hydroxyacyl-CoA dehydrogenase
FNV59_RS39905	COG1024	Enoyl-CoA hydratase
FNV59_RS39910	COG0183	Belongs to the thiolase family
FNV59_RS39920	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FNV59_RS39935	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FNV59_RS39950	COG0446	pyridine nucleotide-disulphide oxidoreductase
FNV59_RS39960	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FNV59_RS39965	COG3253	May function as heme-dependent peroxidase
FNV59_RS39985	COG3220	belongs to the UPF0276 family
FNV59_RS40020	COG2326	polyphosphate kinase activity
FNV59_RS40025	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FNV59_RS40065	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FNV59_RS40070	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FNV59_RS40080	COG0515	serine threonine protein kinase
FNV59_RS40115	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
FNV59_RS40155	COG4999	Histidine kinase
FNV59_RS40155	COG3850	Histidine kinase
FNV59_RS40155	COG2205	protein histidine kinase activity
FNV59_RS40155	COG3437	response regulator, receiver
FNV59_RS40180	COG0154	amidase activity
FNV59_RS40195	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FNV59_RS40220	COG0642	Histidine kinase
FNV59_RS40315	COG0504	CTP synthase activity
FNV59_RS40330	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FNV59_RS40450	COG0667	Aldo Keto reductase
FNV59_RS40455	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FNV59_RS40475	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNV59_RS40480	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FNV59_RS40505	COG0529	Catalyzes the synthesis of activated sulfate
FNV59_RS40510	COG0175	sulfate reduction
FNV59_RS40540	COG1960	acyl-CoA dehydrogenase activity
FNV59_RS40555	COG1917	Cupin 2, conserved barrel domain protein
FNV59_RS40555	COG4977	sequence-specific DNA binding
FNV59_RS40585	COG1609	Transcriptional regulator
FNV59_RS40615	COG0154	amidase activity
FNV59_RS40625	COG2040	homocysteine
FNV59_RS40685	COG0596	Alpha beta hydrolase
FNV59_RS40690	COG1309	transcriptional regulator
FNV59_RS40785	COG3903	Transcriptional regulator
FNV59_RS40785	COG3629	intracellular signal transduction
FNV59_RS40800	COG0702	epimerase
FNV59_RS40890	COG1131	(ABC) transporter
FNV59_RS40910	COG1175	transmembrane transport
FNV59_RS40925	COG0277	FAD linked oxidase domain protein
FNV59_RS41005	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FNV59_RS41015	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FNV59_RS41025	COG1162	GTPase activity
FNV59_RS41075	COG0028	Belongs to the TPP enzyme family
FNV59_RS41095	COG1802	Transcriptional regulator
FNV59_RS41125	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FNV59_RS41130	COG2252	PERMEase
FNV59_RS41160	COG0726	polysaccharide deacetylase
FNV59_RS41165	COG0673	inositol 2-dehydrogenase activity
FNV59_RS41175	COG1132	(ABC) transporter
FNV59_RS41185	COG0596	Alpha beta hydrolase
FNV59_RS41190	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FNV59_RS41210	COG1477	protein flavinylation
FNV59_RS41225	COG0745	RESPONSE REGULATOR receiver
FNV59_RS41230	COG2205	protein histidine kinase activity
FNV59_RS41260	COG3629	intracellular signal transduction
FNV59_RS41260	COG3903	Transcriptional regulator
FNV59_RS41275	COG4977	sequence-specific DNA binding
FNV59_RS41310	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FNV59_RS41325	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FNV59_RS41330	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FNV59_RS41335	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FNV59_RS41410	COG0673	inositol 2-dehydrogenase activity
FNV59_RS41415	COG0667	Aldo Keto reductase
FNV59_RS41465	COG2267	carboxylic ester hydrolase activity
FNV59_RS41485	COG0598	Magnesium transport protein CorA
FNV59_RS41500	COG0583	DNA-binding transcription factor activity
FNV59_RS41520	COG2197	response regulator
FNV59_RS41525	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FNV59_RS41530	COG0318	PFAM AMP-dependent synthetase and ligase
FNV59_RS41540	COG3960	tartronate-semialdehyde synthase activity
FNV59_RS41550	COG0753	catalase activity
FNV59_RS41555	COG2084	Dehydrogenase
FNV59_RS41560	COG3622	Belongs to the hyi family
FNV59_RS41580	COG2351	hydroxyisourate hydrolase activity
FNV59_RS41595	COG2233	PERMEase
FNV59_RS41610	COG1733	regulation of RNA biosynthetic process
FNV59_RS41625	COG0406	alpha-ribazole phosphatase activity
FNV59_RS41630	COG0436	Aminotransferase
FNV59_RS41650	COG2304	oxidoreductase activity
FNV59_RS41655	COG4264	IucA IucC family
FNV59_RS41665	COG0515	serine threonine protein kinase
FNV59_RS41665	COG2815	serine threonine protein kinase
FNV59_RS41685	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FNV59_RS41690	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FNV59_RS41700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FNV59_RS41715	COG1414	Transcriptional regulator
FNV59_RS41720	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FNV59_RS41725	COG4266	Belongs to the allantoicase family
FNV59_RS41730	COG0598	Magnesium transport protein CorA
FNV59_RS41745	COG0667	Aldo Keto reductase
FNV59_RS41750	COG2197	response regulator
FNV59_RS41760	COG0673	inositol 2-dehydrogenase activity
FNV59_RS41765	COG2188	Transcriptional regulator
FNV59_RS41790	COG1940	carbohydrate kinase activity
FNV59_RS41800	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FNV59_RS41810	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FNV59_RS41815	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FNV59_RS41830	COG1126	abc transporter atp-binding protein
FNV59_RS41840	COG0765	amino acid transport
FNV59_RS41845	COG0765	amino acid transport
FNV59_RS41860	COG0405	Gamma-glutamyltransferase
FNV59_RS41900	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FNV59_RS41910	COG1953	Uracil, thiamine, allantoin
FNV59_RS41920	COG2226	methyltransferase
FNV59_RS41930	COG3851	Histidine kinase
FNV59_RS41935	COG2197	response regulator
FNV59_RS41950	COG0483	inositol monophosphate 1-phosphatase activity
FNV59_RS41965	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FNV59_RS41975	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FNV59_RS41980	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FNV59_RS41990	COG1215	transferase activity, transferring glycosyl groups
FNV59_RS42000	COG4310	Domain of unknown function (DUF2172)
FNV59_RS42015	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FNV59_RS42025	COG0438	transferase activity, transferring glycosyl groups
FNV59_RS42050	COG0367	asparagine synthase
FNV59_RS42070	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FNV59_RS42090	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS42095	COG0583	DNA-binding transcription factor activity
FNV59_RS42105	COG0477	Major facilitator Superfamily
FNV59_RS42120	COG1309	transcriptional regulator
FNV59_RS42155	COG0745	RESPONSE REGULATOR receiver
FNV59_RS42170	COG1136	(ABC) transporter
FNV59_RS42180	COG2205	protein histidine kinase activity
FNV59_RS42185	COG2205	protein histidine kinase activity
FNV59_RS42195	COG0671	phosphoesterase, PA-phosphatase related
FNV59_RS42215	COG0640	Transcriptional regulator
FNV59_RS42235	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FNV59_RS42285	COG2130	NADP-dependent
FNV59_RS42290	COG0789	Transcriptional regulator
FNV59_RS42295	COG1192	Involved in chromosome partitioning
FNV59_RS42325	COG1929	Belongs to the glycerate kinase type-1 family
FNV59_RS42335	COG0688	phosphatidylethanolamine metabolic process
FNV59_RS42340	COG1960	acyl-CoA dehydrogenase activity
FNV59_RS42350	COG2301	Belongs to the HpcH HpaI aldolase family
FNV59_RS42355	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FNV59_RS42355	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FNV59_RS42360	COG0604	alcohol dehydrogenase
FNV59_RS42375	COG1250	3-hydroxyacyl-CoA dehydrogenase
FNV59_RS42385	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FNV59_RS42385	COG0456	acetyltransferase
FNV59_RS42395	COG0596	Alpha beta hydrolase
FNV59_RS42415	COG1366	Belongs to the anti-sigma-factor antagonist family
FNV59_RS42415	COG2208	phosphoserine phosphatase activity
FNV59_RS42415	COG2172	sigma factor antagonist activity
FNV59_RS42420	COG2226	methyltransferase
FNV59_RS42460	COG2362	D-Aminopeptidase
FNV59_RS42465	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FNV59_RS42475	COG1619	proteins homologs of microcin C7 resistance protein MccF
FNV59_RS42505	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FNV59_RS42510	COG2226	methyltransferase
FNV59_RS42520	COG0488	(ABC) transporter
FNV59_RS42610	COG0443	Heat shock 70 kDa protein
FNV59_RS42625	COG2154	pterin-4-alpha-carbinolamine dehydratase
FNV59_RS42630	COG2226	methyltransferase
FNV59_RS42645	COG2378	regulation of single-species biofilm formation
FNV59_RS42650	COG3401	FG-GAP repeat protein
FNV59_RS42660	COG5297	Belongs to the glycosyl hydrolase family 6
FNV59_RS42660	COG4733	cellulase activity
FNV59_RS42670	COG5297	Belongs to the glycosyl hydrolase family 6
FNV59_RS42690	COG2319	Wd-40 repeat
FNV59_RS42690	COG4249	Peptidase C14 caspase catalytic subunit p20
FNV59_RS42695	COG4221	oxidoreductase activity
FNV59_RS42705	COG0656	L-ascorbic acid biosynthetic process
FNV59_RS42730	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FNV59_RS42740	COG3469	chitinase activity
FNV59_RS42745	COG3250	beta-galactosidase activity
FNV59_RS42755	COG0477	Major facilitator Superfamily
FNV59_RS42790	COG1846	Transcriptional regulator
FNV59_RS42795	COG1335	isochorismatase
FNV59_RS42805	COG0583	DNA-binding transcription factor activity
FNV59_RS42810	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FNV59_RS42825	COG3383	formate dehydrogenase (NAD+) activity
FNV59_RS42830	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FNV59_RS42840	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FNV59_RS42850	COG1940	carbohydrate kinase activity
FNV59_RS42855	COG1129	ABC transporter
FNV59_RS42860	COG1172	Belongs to the binding-protein-dependent transport system permease family
FNV59_RS42865	COG1879	ABC-type sugar transport system periplasmic component
FNV59_RS42870	COG0673	inositol 2-dehydrogenase activity
FNV59_RS42880	COG3507	Belongs to the glycosyl hydrolase 43 family
FNV59_RS42895	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FNV59_RS42910	COG0084	hydrolase, TatD family'
FNV59_RS42935	COG2223	nitrite transmembrane transporter activity
FNV59_RS42945	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNV59_RS42955	COG0045	succinate-CoA ligase (ADP-forming) activity
FNV59_RS42965	COG1012	belongs to the aldehyde dehydrogenase family
FNV59_RS43000	COG0784	Response regulator, receiver
FNV59_RS43000	COG5002	protein histidine kinase activity
FNV59_RS43025	COG0789	Transcriptional regulator
FNV59_RS43065	COG0402	S-adenosylhomocysteine deaminase activity
FNV59_RS43095	COG2226	methyltransferase
FNV59_RS43115	COG4044	May play a role in the intracellular transport of hydrophobic ligands
FNV59_RS43125	COG4221	oxidoreductase activity
FNV59_RS43150	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FNV59_RS43155	COG0254	rRNA binding
FNV59_RS43165	COG4585	Histidine kinase
FNV59_RS43170	COG2197	response regulator
FNV59_RS43195	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FNV59_RS43200	COG2072	flavoprotein involved in K transport
FNV59_RS43220	COG0022	dehydrogenase e1 component
FNV59_RS43225	COG1309	transcriptional regulator
FNV59_RS43230	COG1960	acyl-CoA dehydrogenase activity
FNV59_RS43235	COG1063	alcohol dehydrogenase
FNV59_RS43250	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS43255	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS43260	COG0745	RESPONSE REGULATOR receiver
FNV59_RS43315	COG0542	response to heat
FNV59_RS43345	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNV59_RS43350	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
FNV59_RS43365	COG1063	alcohol dehydrogenase
FNV59_RS43375	COG0745	RESPONSE REGULATOR receiver
FNV59_RS43385	COG0477	Major facilitator Superfamily
FNV59_RS43390	COG2124	cytochrome p450
FNV59_RS43410	COG0477	Major facilitator Superfamily
FNV59_RS43445	COG2353	YceI-like domain
FNV59_RS43455	COG0765	amino acid transport
FNV59_RS43460	COG1126	abc transporter atp-binding protein
FNV59_RS43465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNV59_RS43475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV59_RS43480	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV59_RS43485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV59_RS43490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV59_RS43505	COG0596	Alpha beta hydrolase
FNV59_RS43505	COG0508	dehydrogenase complex catalyzes the overall conversion of
FNV59_RS43515	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FNV59_RS43540	COG0438	transferase activity, transferring glycosyl groups
FNV59_RS43560	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FNV59_RS43590	COG0477	Major facilitator Superfamily
FNV59_RS43600	COG3467	pyridoxamine 5'-phosphate
FNV59_RS43615	COG0477	Major facilitator Superfamily
FNV59_RS43625	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FNV59_RS43630	COG1082	Xylose isomerase domain protein TIM barrel
FNV59_RS43630	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FNV59_RS43645	COG0588	phosphoglycerate mutase activity
FNV59_RS43650	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FNV59_RS43655	COG0166	Belongs to the GPI family
FNV59_RS43670	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FNV59_RS43705	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS43730	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FNV59_RS43735	COG3250	beta-galactosidase activity
FNV59_RS43740	COG0395	ABC-type sugar transport system, permease component
FNV59_RS43745	COG1175	transmembrane transport
FNV59_RS43755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNV59_RS43760	COG1349	DNA-binding transcription factor activity
FNV59_RS43765	COG1486	melibiose metabolic process
FNV59_RS43775	COG3469	chitinase activity
FNV59_RS43785	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FNV59_RS43840	COG3842	ATPase activity
FNV59_RS43845	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FNV59_RS43850	COG1176	ABC-type spermidine putrescine transport system, permease component I
FNV59_RS43855	COG1177	transmembrane transport
FNV59_RS43945	COG1181	Belongs to the D-alanine--D-alanine ligase family
FNV59_RS43950	COG2258	MOSC domain
FNV59_RS43955	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FNV59_RS43955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNV59_RS43975	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FNV59_RS43985	COG1181	Belongs to the D-alanine--D-alanine ligase family
FNV59_RS44010	COG2175	clavaminate synthase activity
FNV59_RS44040	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FNV59_RS44055	COG1770	oligopeptidase
FNV59_RS44060	COG2423	ornithine cyclodeaminase activity
FNV59_RS44065	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FNV59_RS44165	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FNV59_RS44170	COG3938	Belongs to the proline racemase family
FNV59_RS44190	COG1175	transmembrane transport
FNV59_RS44195	COG0395	ABC-type sugar transport system, permease component
FNV59_RS44200	COG0366	Alpha amylase catalytic
FNV59_RS44210	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNV59_RS44215	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNV59_RS44320	COG3511	phospholipase C
FNV59_RS44350	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FNV59_RS44355	COG0477	Major facilitator Superfamily
FNV59_RS44365	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FNV59_RS44375	COG3485	protocatechuate 3,4-dioxygenase
FNV59_RS44380	COG3485	protocatechuate 3,4-dioxygenase
FNV59_RS44385	COG0183	Belongs to the thiolase family
FNV59_RS44400	COG1846	Transcriptional regulator
FNV59_RS44410	COG0714	Associated with various cellular activities
FNV59_RS44425	COG1793	dna ligase
FNV59_RS44435	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FNV59_RS44505	COG1834	amidinotransferase
FNV59_RS44510	COG0488	(ABC) transporter
FNV59_RS44520	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FNV59_RS44540	COG1515	deoxyribonuclease V activity
FNV59_RS44545	COG3268	Saccharopine dehydrogenase
FNV59_RS44550	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNV59_RS44555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV59_RS44560	COG1960	acyl-CoA dehydrogenase activity
FNV59_RS44565	COG0183	Belongs to the thiolase family
FNV59_RS44570	COG1250	3-hydroxyacyl-CoA dehydrogenase
FNV59_RS44570	COG1024	Enoyl-CoA hydratase
FNV59_RS44575	COG0789	Transcriptional regulator
FNV59_RS44580	COG1113	amino acid transport
FNV59_RS44590	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FNV59_RS44600	COG2936	dipeptidyl-peptidase activity
FNV59_RS44615	COG0488	(ABC) transporter
FNV59_RS44625	COG2183	response to ionizing radiation
FNV59_RS44635	COG4977	sequence-specific DNA binding
FNV59_RS44645	COG1024	Enoyl-CoA hydratase
FNV59_RS44660	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FNV59_RS44665	COG4106	trans-aconitate 2-methyltransferase activity
FNV59_RS44665	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FNV59_RS44710	COG1134	teichoic acid transport
FNV59_RS44715	COG1562	ergosterol biosynthetic process
FNV59_RS44725	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FNV59_RS44735	COG1657	PFAM Prenyltransferase squalene oxidase
FNV59_RS44750	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FNV59_RS44755	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FNV59_RS44775	COG2365	Tyrosine phosphatase family
FNV59_RS44790	COG3401	FG-GAP repeat protein
FNV59_RS44800	COG2755	lipolytic protein G-D-S-L family
FNV59_RS44815	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FNV59_RS44860	COG1063	alcohol dehydrogenase
FNV59_RS44865	COG0156	8-amino-7-oxononanoate synthase activity
FNV59_RS44870	COG0583	DNA-binding transcription factor activity
FNV59_RS44905	COG3958	Transketolase
FNV59_RS44910	COG3959	Transketolase, thiamine diphosphate binding domain
FNV59_RS44930	COG1132	(ABC) transporter
FNV59_RS44960	COG3033	Beta-eliminating lyase
FNV59_RS44980	COG1937	Protein conserved in bacteria
FNV59_RS45000	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FNV59_RS45020	COG3239	Fatty acid desaturase
FNV59_RS45030	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FNV59_RS45120	COG3485	protocatechuate 3,4-dioxygenase
FNV59_RS45125	COG1454	alcohol dehydrogenase
FNV59_RS45135	COG0351	phosphomethylpyrimidine kinase
FNV59_RS45140	COG0702	epimerase
FNV59_RS45190	COG1595	DNA-templated transcription, initiation
FNV59_RS45200	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FNV59_RS45215	COG1053	succinate dehydrogenase
FNV59_RS45220	COG1764	response to oxidative stress
FNV59_RS45225	COG1595	DNA-templated transcription, initiation
FNV59_RS45280	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FNV59_RS45305	COG2838	Isocitrate dehydrogenase
FNV59_RS45310	COG0668	transmembrane transport
FNV59_RS45315	COG1024	Enoyl-CoA hydratase
FNV59_RS45330	COG2409	Drug exporters of the RND superfamily
FNV59_RS45335	COG1309	transcriptional regulator
FNV59_RS45340	COG0473	3-isopropylmalate dehydrogenase activity
FNV59_RS45350	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FNV59_RS45365	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FNV59_RS45380	COG3483	tryptophan 2,3-dioxygenase activity
FNV59_RS45395	COG0475	glutathione-regulated potassium exporter activity
FNV59_RS45400	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FNV59_RS45415	COG2264	protein methyltransferase activity
FNV59_RS45445	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FNV59_RS45460	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FNV59_RS45465	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FNV59_RS45470	COG0697	spore germination
FNV59_RS45475	COG1509	lysine 2,3-aminomutase activity
FNV59_RS45485	COG0579	oxidoreductase
FNV59_RS45535	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FNV59_RS45555	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FNV59_RS45575	COG0297	glycogen (starch) synthase activity
FNV59_RS45580	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FNV59_RS45600	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FNV59_RS45605	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS45615	COG0701	Predicted permease
FNV59_RS45645	COG1609	Transcriptional regulator
FNV59_RS45655	COG1175	transmembrane transport
FNV59_RS45660	COG0395	ABC-type sugar transport system, permease component
FNV59_RS45680	COG2186	Transcriptional regulator
FNV59_RS45685	COG1879	ABC-type sugar transport system periplasmic component
FNV59_RS45690	COG1129	ABC transporter
FNV59_RS45700	COG4948	Mandelate Racemase Muconate Lactonizing
FNV59_RS45705	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS45740	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FNV59_RS45775	COG0726	polysaccharide deacetylase
FNV59_RS45825	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS45830	COG0583	DNA-binding transcription factor activity
FNV59_RS45840	COG1053	succinate dehydrogenase
FNV59_RS45845	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FNV59_RS45865	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV59_RS45885	COG0667	Aldo Keto reductase
FNV59_RS45920	COG1595	DNA-templated transcription, initiation
FNV59_RS45965	COG2814	Major facilitator Superfamily
FNV59_RS45970	COG0583	DNA-binding transcription factor activity
FNV59_RS45975	COG0583	DNA-binding transcription factor activity
FNV59_RS45990	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FNV59_RS45995	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FNV59_RS46000	COG2080	2 iron, 2 sulfur cluster binding
FNV59_RS46015	COG0667	Aldo Keto reductase
FNV59_RS46050	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
FNV59_RS46055	COG0121	glutamine amidotransferase
FNV59_RS46060	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FNV59_RS46065	COG3572	ergothioneine biosynthetic process
FNV59_RS46085	COG2268	Band 7 protein
FNV59_RS46100	COG1609	Transcriptional regulator
FNV59_RS46115	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FNV59_RS46125	COG0242	peptide deformylase activity
FNV59_RS46210	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FNV59_RS46225	COG1408	metallophosphoesterase
FNV59_RS46230	COG2226	methyltransferase
FNV59_RS46280	COG2378	regulation of single-species biofilm formation
FNV59_RS46305	COG1609	Transcriptional regulator
FNV59_RS46320	COG0395	ABC-type sugar transport system, permease component
FNV59_RS46355	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FNV59_RS46375	COG1309	transcriptional regulator
FNV59_RS46380	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS46410	COG0163	prenyltransferase activity
FNV59_RS46450	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FNV59_RS46470	COG2318	DinB family
FNV59_RS46490	COG1733	regulation of RNA biosynthetic process
FNV59_RS46500	COG2366	antibiotic biosynthetic process
FNV59_RS46505	COG1073	alpha beta
FNV59_RS46555	COG0583	DNA-binding transcription factor activity
FNV59_RS46560	COG2130	NADP-dependent
FNV59_RS46585	COG2072	flavoprotein involved in K transport
FNV59_RS46590	COG0667	Aldo Keto reductase
FNV59_RS46595	COG1902	pentaerythritol trinitrate reductase activity
FNV59_RS46615	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS46630	COG0183	Belongs to the thiolase family
FNV59_RS46650	COG3485	protocatechuate 3,4-dioxygenase
FNV59_RS46660	COG2909	trisaccharide binding
FNV59_RS46685	COG0778	Nitroreductase
FNV59_RS46740	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FNV59_RS46750	COG3537	Alpha-1,2-mannosidase
FNV59_RS46775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV59_RS46795	COG0477	Major facilitator Superfamily
FNV59_RS46815	COG0006	proline dipeptidase activity
FNV59_RS46820	COG3291	Pkd domain containing protein
FNV59_RS46830	COG0673	inositol 2-dehydrogenase activity
FNV59_RS46845	COG1609	Transcriptional regulator
FNV59_RS46850	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FNV59_RS46885	COG1122	ATPase activity
FNV59_RS46890	COG1122	ATPase activity
FNV59_RS46895	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FNV59_RS46920	COG0561	phosphatase activity
FNV59_RS46995	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FNV59_RS47000	COG2151	metal-sulfur cluster biosynthetic enzyme
FNV59_RS47005	COG3396	Phenylacetate-CoA oxygenase
FNV59_RS47010	COG3460	Phenylacetate-CoA oxygenase
FNV59_RS47015	COG3396	Phenylacetate-CoA oxygenase
FNV59_RS47020	COG1250	3-hydroxyacyl-CoA dehydrogenase
FNV59_RS47040	COG2050	protein possibly involved in aromatic compounds catabolism
FNV59_RS47055	COG0531	amino acid
FNV59_RS47125	COG2226	methyltransferase
FNV59_RS47150	COG1024	Enoyl-CoA hydratase
FNV59_RS47150	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FNV59_RS47160	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
FNV59_RS47190	COG0375	protein maturation
FNV59_RS47195	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FNV59_RS47200	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FNV59_RS47205	COG0298	carbon dioxide binding
FNV59_RS47210	COG0409	Hydrogenase expression formation protein
FNV59_RS47215	COG0309	Hydrogenase expression formation protein (HypE)
FNV59_RS47245	COG1141	Ferredoxin
FNV59_RS47275	COG1136	(ABC) transporter
FNV59_RS47280	COG1174	glycine betaine transport
FNV59_RS47285	COG1174	glycine betaine transport
FNV59_RS47310	COG1556	Lactate utilization protein
FNV59_RS47315	COG1139	Iron-sulfur cluster binding protein
FNV59_RS47320	COG0247	lactate metabolic process
FNV59_RS47325	COG1070	Carbohydrate kinase
FNV59_RS47330	COG3347	Dehydrogenase
FNV59_RS47330	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS47340	COG1129	ABC transporter
FNV59_RS47375	COG1609	Transcriptional regulator
FNV59_RS47385	COG1595	DNA-templated transcription, initiation
FNV59_RS47390	COG1357	PFAM Pentapeptide repeats (8 copies)
FNV59_RS47400	COG1309	transcriptional regulator
FNV59_RS47410	COG2706	6-phosphogluconolactonase activity
FNV59_RS47435	COG0604	alcohol dehydrogenase
FNV59_RS47435	COG3321	synthase
FNV59_RS47435	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS47460	COG2723	6-phospho-beta-galactosidase activity
FNV59_RS47465	COG0395	ABC-type sugar transport system, permease component
FNV59_RS47470	COG1175	transmembrane transport
FNV59_RS47475	COG2182	Extracellular solute-binding protein
FNV59_RS47500	COG2267	carboxylic ester hydrolase activity
FNV59_RS47510	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FNV59_RS47510	COG1796	DNA polymerase
FNV59_RS47560	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FNV59_RS47585	COG0515	serine threonine protein kinase
FNV59_RS47630	COG0640	Transcriptional regulator
FNV59_RS47640	COG0772	Belongs to the SEDS family
FNV59_RS47675	COG1316	TRANSCRIPTIONal
FNV59_RS47685	COG1278	Cold shock
FNV59_RS47725	COG0515	serine threonine protein kinase
FNV59_RS47735	COG1132	(ABC) transporter
FNV59_RS47740	COG1132	(ABC) transporter
FNV59_RS47745	COG2197	response regulator
FNV59_RS47755	COG0531	amino acid
FNV59_RS47870	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FNV59_RS47870	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
FNV59_RS47895	COG1609	Transcriptional regulator
FNV59_RS47920	COG1621	beta-fructofuranosidase activity
FNV59_RS48010	COG2208	phosphoserine phosphatase activity
FNV59_RS48010	COG2172	sigma factor antagonist activity
FNV59_RS48010	COG1366	Belongs to the anti-sigma-factor antagonist family
FNV59_RS48025	COG0789	Transcriptional regulator
FNV59_RS48045	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FNV59_RS48165	COG0745	RESPONSE REGULATOR receiver
FNV59_RS48225	COG2132	Multicopper oxidase
FNV59_RS48250	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FNV59_RS48270	COG1012	belongs to the aldehyde dehydrogenase family
FNV59_RS48310	COG0318	PFAM AMP-dependent synthetase and ligase
FNV59_RS48320	COG0531	amino acid
FNV59_RS48360	COG2124	cytochrome p450
FNV59_RS48400	COG0596	Alpha beta hydrolase
FNV59_RS48405	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FNV59_RS48405	COG1672	PFAM Archaeal ATPase
FNV59_RS48435	COG3250	beta-galactosidase activity
FNV59_RS48440	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FNV59_RS48465	COG0640	Transcriptional regulator
FNV59_RS48500	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FNV59_RS48535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV59_RS48550	COG4209	transmembrane transport
FNV59_RS48555	COG0395	ABC-type sugar transport system, permease component
FNV59_RS48565	COG1609	Transcriptional regulator
FNV59_RS48580	COG0671	phosphoesterase, PA-phosphatase related
FNV59_RS48595	COG3832	glyoxalase III activity
FNV59_RS48640	COG2755	lipolytic protein G-D-S-L family
FNV59_RS48640	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FNV59_RS48655	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FNV59_RS48705	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FNV59_RS48720	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FNV59_RS48735	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FNV59_RS48760	COG1132	(ABC) transporter
FNV59_RS48805	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNV59_RS48810	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS48840	COG1940	carbohydrate kinase activity
FNV59_RS48840	COG1846	Transcriptional regulator
FNV59_RS48860	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
FNV59_RS48885	COG1595	DNA-templated transcription, initiation
FNV59_RS48930	COG4948	Mandelate Racemase Muconate Lactonizing
FNV59_RS48940	COG0583	DNA-binding transcription factor activity
FNV59_RS48985	COG1404	Belongs to the peptidase S8 family
FNV59_RS49010	COG2318	DinB family
FNV59_RS49045	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FNV59_RS49050	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FNV59_RS49055	COG2409	Drug exporters of the RND superfamily
FNV59_RS49085	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS49090	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS49150	COG1802	Transcriptional regulator
FNV59_RS49215	COG0384	phenazine biosynthesis protein PhzF
FNV59_RS49225	COG0583	DNA-binding transcription factor activity
FNV59_RS49250	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS49290	COG1278	Cold shock
FNV59_RS49315	COG3552	Protein containing von Willebrand factor type A (VWA) domain
FNV59_RS49320	COG0714	Associated with various cellular activities
FNV59_RS49350	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FNV59_RS49360	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FNV59_RS49370	COG0596	Alpha beta hydrolase
FNV59_RS49385	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FNV59_RS49400	COG1940	carbohydrate kinase activity
FNV59_RS49410	COG1175	transmembrane transport
FNV59_RS49415	COG0395	ABC-type sugar transport system, permease component
FNV59_RS49440	COG2340	Cysteine-rich secretory protein family
FNV59_RS49485	COG3469	chitinase activity
FNV59_RS49495	COG3548	integral membrane protein
FNV59_RS49505	COG0667	Aldo Keto reductase
FNV59_RS49515	COG3537	Alpha-1,2-mannosidase
FNV59_RS49540	COG1129	ABC transporter
FNV59_RS49560	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS49565	COG1960	acyl-CoA dehydrogenase activity
FNV59_RS49570	COG1024	Enoyl-CoA hydratase
FNV59_RS49580	COG0183	Belongs to the thiolase family
FNV59_RS49585	COG1960	acyl-CoA dehydrogenase activity
FNV59_RS49595	COG1960	acyl-CoA dehydrogenase activity
FNV59_RS49600	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS49605	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS49610	COG1024	Enoyl-CoA hydratase
FNV59_RS49640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNV59_RS49655	COG1228	amidohydrolase
FNV59_RS49660	COG0515	serine threonine protein kinase
FNV59_RS49670	COG3250	beta-galactosidase activity
FNV59_RS49695	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FNV59_RS49700	COG0730	response to heat
FNV59_RS49705	COG1937	Protein conserved in bacteria
FNV59_RS49745	COG1175	transmembrane transport
FNV59_RS49770	COG3345	alpha-galactosidase
FNV59_RS49780	COG0667	Aldo Keto reductase
FNV59_RS49785	COG1335	isochorismatase
FNV59_RS49805	COG3852	Histidine kinase
FNV59_RS49810	COG0492	ferredoxin-NADP+ reductase activity
FNV59_RS49840	COG3290	protein histidine kinase activity
FNV59_RS49850	COG2814	Major facilitator Superfamily
FNV59_RS49875	COG1716	ATPase activity
FNV59_RS49875	COG1131	(ABC) transporter
FNV59_RS49875	COG0842	Transport permease protein
FNV59_RS49910	COG0739	heme binding
FNV59_RS49930	COG0583	DNA-binding transcription factor activity
FNV59_RS49935	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FNV59_RS49950	COG2197	response regulator
FNV59_RS49970	COG0395	ABC-type sugar transport system, permease component
FNV59_RS49985	COG1335	isochorismatase
FNV59_RS49995	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FNV59_RS50010	COG5002	protein histidine kinase activity
FNV59_RS50020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNV59_RS50025	COG1053	succinate dehydrogenase
FNV59_RS50035	COG2318	DinB family
FNV59_RS50045	COG2318	DinB family
FNV59_RS50090	COG0596	Alpha beta hydrolase
FNV59_RS50095	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FNV59_RS50095	COG1017	nitric oxide dioxygenase activity
FNV59_RS50120	COG1595	DNA-templated transcription, initiation
FNV59_RS50140	COG0745	RESPONSE REGULATOR receiver
FNV59_RS50170	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FNV59_RS50180	COG2080	2 iron, 2 sulfur cluster binding
FNV59_RS50180	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FNV59_RS50205	COG2197	response regulator
FNV59_RS50230	COG4191	Histidine kinase
FNV59_RS50240	COG0517	IMP dehydrogenase activity
FNV59_RS50240	COG0516	GMP reductase activity
FNV59_RS50285	COG2326	polyphosphate kinase activity
FNV59_RS50290	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
FNV59_RS50295	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FNV59_RS50315	COG1042	CoA-binding domain protein
FNV59_RS50315	COG0045	succinate-CoA ligase (ADP-forming) activity
FNV59_RS50315	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FNV59_RS50320	COG0517	IMP dehydrogenase activity
FNV59_RS50320	COG0516	GMP reductase activity
FNV59_RS50340	COG0517	IMP dehydrogenase activity
FNV59_RS50340	COG0516	GMP reductase activity
FNV59_RS50355	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FNV59_RS50355	COG0574	Belongs to the PEP-utilizing enzyme family
FNV59_RS50390	COG0516	GMP reductase activity
FNV59_RS50390	COG0517	IMP dehydrogenase activity
FNV59_RS50400	COG0517	IMP dehydrogenase activity
FNV59_RS50400	COG0516	GMP reductase activity
FNV59_RS50420	COG2239	Acts as a magnesium transporter
FNV59_RS50485	COG1063	alcohol dehydrogenase
FNV59_RS50500	COG0531	amino acid
FNV59_RS50505	COG2235	arginine
FNV59_RS50510	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FNV59_RS50515	COG0549	Belongs to the carbamate kinase family
FNV59_RS50525	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FNV59_RS50555	COG1309	transcriptional regulator
FNV59_RS50560	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS50575	COG1278	Cold shock
FNV59_RS50580	COG0513	Belongs to the DEAD box helicase family
FNV59_RS50630	COG1132	(ABC) transporter
FNV59_RS50665	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FNV59_RS50670	COG2226	methyltransferase
FNV59_RS50675	COG5640	endopeptidase activity
FNV59_RS50690	COG0789	Transcriptional regulator
FNV59_RS50720	COG1132	(ABC) transporter
FNV59_RS50730	COG2318	DinB family
FNV59_RS50750	COG1012	belongs to the aldehyde dehydrogenase family
FNV59_RS50755	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FNV59_RS50760	COG1414	Transcriptional regulator
FNV59_RS50775	COG4106	trans-aconitate 2-methyltransferase activity
FNV59_RS50805	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV59_RS50810	COG1335	isochorismatase
FNV59_RS50835	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FNV59_RS50900	COG2208	phosphoserine phosphatase activity
FNV59_RS50915	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FNV59_RS50950	COG0583	DNA-binding transcription factor activity
FNV59_RS50955	COG0243	molybdopterin cofactor binding
FNV59_RS50990	COG2837	iron assimilation
FNV59_RS51000	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS51005	COG0657	acetylesterase activity
FNV59_RS51015	COG2207	Transcriptional regulator
FNV59_RS51025	COG0745	RESPONSE REGULATOR receiver
FNV59_RS51030	COG2205	protein histidine kinase activity
FNV59_RS51130	COG1309	transcriptional regulator
FNV59_RS51145	COG1309	transcriptional regulator
FNV59_RS51150	COG1064	alcohol dehydrogenase
FNV59_RS51165	COG1172	Belongs to the binding-protein-dependent transport system permease family
FNV59_RS51170	COG1129	ABC transporter
FNV59_RS51180	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS51235	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS51240	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS51265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNV59_RS51280	COG1522	sequence-specific DNA binding
FNV59_RS51330	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FNV59_RS51355	COG1595	DNA-templated transcription, initiation
FNV59_RS51385	COG2267	carboxylic ester hydrolase activity
FNV59_RS51400	COG0531	amino acid
FNV59_RS51415	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS51420	COG4221	oxidoreductase activity
FNV59_RS51445	COG4941	Belongs to the sigma-70 factor family
FNV59_RS51450	COG3795	YCII-related domain
FNV59_RS51505	COG1309	transcriptional regulator
FNV59_RS51510	COG0667	Aldo Keto reductase
FNV59_RS51540	COG2124	cytochrome p450
FNV59_RS51570	COG2197	response regulator
FNV59_RS51600	COG2197	response regulator
FNV59_RS51605	COG4585	Histidine kinase
FNV59_RS51610	COG4552	Acetyltransferase involved in intracellular survival and related
FNV59_RS51650	COG0596	Alpha beta hydrolase
FNV59_RS51670	COG2197	response regulator
FNV59_RS51685	COG1902	pentaerythritol trinitrate reductase activity
FNV59_RS51685	COG0446	pyridine nucleotide-disulphide oxidoreductase
FNV59_RS51690	COG1012	belongs to the aldehyde dehydrogenase family
FNV59_RS51695	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FNV59_RS51705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV59_RS51720	COG0583	DNA-binding transcription factor activity
FNV59_RS51725	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS51750	COG0745	RESPONSE REGULATOR receiver
FNV59_RS51840	COG1309	transcriptional regulator
FNV59_RS51850	COG1309	transcriptional regulator
FNV59_RS51915	COG1012	belongs to the aldehyde dehydrogenase family
FNV59_RS51930	COG0596	Alpha beta hydrolase
FNV59_RS51945	COG0604	alcohol dehydrogenase
FNV59_RS51945	COG3321	synthase
FNV59_RS52000	COG0326	Molecular chaperone. Has ATPase activity
FNV59_RS52010	COG2409	Drug exporters of the RND superfamily
FNV59_RS52020	COG2072	flavoprotein involved in K transport
FNV59_RS52030	COG1012	belongs to the aldehyde dehydrogenase family
FNV59_RS52050	COG4974	Belongs to the 'phage' integrase family
FNV59_RS52105	COG4977	sequence-specific DNA binding
FNV59_RS52125	COG1024	Enoyl-CoA hydratase
FNV59_RS52185	COG1902	pentaerythritol trinitrate reductase activity
FNV59_RS52185	COG0446	pyridine nucleotide-disulphide oxidoreductase
FNV59_RS52215	COG4221	oxidoreductase activity
FNV59_RS52225	COG0477	Major facilitator Superfamily
FNV59_RS52240	COG0477	Major facilitator Superfamily
FNV59_RS52245	COG0477	Major facilitator Superfamily
FNV59_RS52265	COG1609	Transcriptional regulator
FNV59_RS52290	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FNV59_RS52295	COG0667	Aldo Keto reductase
FNV59_RS52315	COG0300	oxidoreductase activity
FNV59_RS52355	COG1802	Transcriptional regulator
FNV59_RS52360	COG2205	protein histidine kinase activity
FNV59_RS52365	COG0745	RESPONSE REGULATOR receiver
FNV59_RS52370	COG2409	Drug exporters of the RND superfamily
FNV59_RS52405	COG0657	acetylesterase activity
FNV59_RS52490	COG2261	transglycosylase associated protein
FNV59_RS52495	COG0640	Transcriptional regulator
FNV59_RS52505	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FNV59_RS52520	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FNV59_RS52575	COG0179	Fumarylacetoacetate (FAA) hydrolase
FNV59_RS52590	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FNV59_RS52615	COG0202	RNA polymerase activity
FNV59_RS52630	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FNV59_RS52680	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FNV59_RS52710	COG4977	sequence-specific DNA binding
FNV59_RS52725	COG0477	Major facilitator Superfamily
FNV59_RS52815	COG2208	phosphoserine phosphatase activity
FNV59_RS52815	COG2770	Histidine kinase
FNV59_RS52860	COG2272	Belongs to the type-B carboxylesterase lipase family
FNV59_RS52870	COG2197	response regulator
FNV59_RS52945	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FNV59_RS52990	COG0604	alcohol dehydrogenase
FNV59_RS52990	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FNV59_RS52990	COG3321	synthase
FNV59_RS52990	COG4221	oxidoreductase activity
FNV59_RS53015	COG1028	Short-chain dehydrogenase reductase Sdr
FNV59_RS53085	COG4585	Histidine kinase
FNV59_RS53110	COG2135	peptidase activity
FNV59_RS53190	COG1309	transcriptional regulator
FNV59_RS53270	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FNV59_RS53280	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FNV59_RS53335	COG2192	nodulation
FNV59_RS53355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNV59_RS53360	COG0483	inositol monophosphate 1-phosphatase activity
FNV59_RS53365	COG0583	DNA-binding transcription factor activity
FNV59_RS53420	COG0563	adenylate kinase activity
FNV59_RS53460	COG2159	amidohydrolase
FNV59_RS53480	COG2226	methyltransferase
FNV59_RS53485	COG3328	transposase activity
FNV59_RS53525	COG2197	response regulator
FNV59_RS53570	COG1674	ftsk spoiiie
FNV59_RS53620	COG4584	PFAM Integrase catalytic
FNV59_RS53625	COG1484	DNA-dependent DNA replication