locus-tag	class	description
A7B19_RS00105	COG1113	amino acid transport
A7B19_RS00140	COG0252	asparaginase activity
A7B19_RS00160	COG1960	acyl-CoA dehydrogenase activity
A7B19_RS00170	COG4608	Belongs to the ABC transporter superfamily
A7B19_RS00175	COG1122	ATPase activity
A7B19_RS00180	COG0444	Belongs to the ABC transporter superfamily
A7B19_RS00185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A7B19_RS00190	COG0601	transmembrane transport
A7B19_RS00195	COG0747	negative chemotaxis
A7B19_RS00300	COG0667	Aldo Keto reductase
A7B19_RS00315	COG2267	carboxylic ester hydrolase activity
A7B19_RS00340	COG0604	alcohol dehydrogenase
A7B19_RS00400	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS00430	COG0789	Transcriptional regulator
A7B19_RS00450	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A7B19_RS00460	COG2271	Major facilitator Superfamily
A7B19_RS00470	COG0492	ferredoxin-NADP+ reductase activity
A7B19_RS00470	COG3118	belongs to the thioredoxin family
A7B19_RS00485	COG1609	Transcriptional regulator
A7B19_RS00490	COG2271	Major facilitator Superfamily
A7B19_RS00495	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A7B19_RS00500	COG2319	Wd-40 repeat
A7B19_RS00500	COG4249	Peptidase C14 caspase catalytic subunit p20
A7B19_RS00510	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A7B19_RS00515	COG0277	FAD linked oxidase domain protein
A7B19_RS00515	COG0247	lactate metabolic process
A7B19_RS00520	COG0028	Belongs to the TPP enzyme family
A7B19_RS00560	COG1309	transcriptional regulator
A7B19_RS00585	COG1131	(ABC) transporter
A7B19_RS00595	COG0745	RESPONSE REGULATOR receiver
A7B19_RS00600	COG2205	protein histidine kinase activity
A7B19_RS00625	COG2130	NADP-dependent
A7B19_RS00630	COG1902	pentaerythritol trinitrate reductase activity
A7B19_RS00630	COG0446	pyridine nucleotide-disulphide oxidoreductase
A7B19_RS00640	COG3250	beta-galactosidase activity
A7B19_RS00680	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
A7B19_RS00685	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A7B19_RS00690	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
A7B19_RS00705	COG3842	ATPase activity
A7B19_RS00710	COG1177	transmembrane transport
A7B19_RS00715	COG1176	ABC-type spermidine putrescine transport system, permease component I
A7B19_RS00735	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
A7B19_RS00750	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
A7B19_RS00760	COG1960	acyl-CoA dehydrogenase activity
A7B19_RS00765	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A7B19_RS00775	COG1309	transcriptional regulator
A7B19_RS00780	COG2814	Major facilitator Superfamily
A7B19_RS00790	COG1309	transcriptional regulator
A7B19_RS00805	COG0395	ABC-type sugar transport system, permease component
A7B19_RS00810	COG3250	beta-galactosidase activity
A7B19_RS00845	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
A7B19_RS00950	COG1674	ftsk spoiiie
A7B19_RS00955	COG1404	Belongs to the peptidase S8 family
A7B19_RS00995	COG1233	COG1233 Phytoene dehydrogenase and related
A7B19_RS01000	COG1609	Transcriptional regulator
A7B19_RS01045	COG0328	RNA-DNA hybrid ribonuclease activity
A7B19_RS01055	COG0154	amidase activity
A7B19_RS01065	COG2226	methyltransferase
A7B19_RS01125	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A7B19_RS01130	COG0601	transmembrane transport
A7B19_RS01180	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A7B19_RS01195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A7B19_RS01205	COG0720	synthase
A7B19_RS01215	COG0302	gtp cyclohydrolase
A7B19_RS01220	COG1132	(ABC) transporter
A7B19_RS01225	COG1132	(ABC) transporter
A7B19_RS01240	COG0583	DNA-binding transcription factor activity
A7B19_RS01410	COG3629	intracellular signal transduction
A7B19_RS01410	COG3903	Transcriptional regulator
A7B19_RS01425	COG2815	serine threonine protein kinase
A7B19_RS01425	COG0515	serine threonine protein kinase
A7B19_RS01430	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A7B19_RS01460	COG1024	Enoyl-CoA hydratase
A7B19_RS01465	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS01470	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS01485	COG1960	acyl-CoA dehydrogenase activity
A7B19_RS01490	COG0183	Belongs to the thiolase family
A7B19_RS01500	COG1024	Enoyl-CoA hydratase
A7B19_RS01505	COG1960	acyl-CoA dehydrogenase activity
A7B19_RS01525	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS01535	COG0435	Glutathione S-transferase
A7B19_RS01560	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS01575	COG1959	2 iron, 2 sulfur cluster binding
A7B19_RS01580	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A7B19_RS01580	COG1017	nitric oxide dioxygenase activity
A7B19_RS01585	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
A7B19_RS01590	COG2345	Transcriptional regulator
A7B19_RS01600	COG4585	Histidine kinase
A7B19_RS01605	COG2197	response regulator
A7B19_RS01620	COG1082	Xylose isomerase domain protein TIM barrel
A7B19_RS01630	COG1796	DNA polymerase
A7B19_RS01630	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
A7B19_RS01675	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A7B19_RS01680	COG0667	Aldo Keto reductase
A7B19_RS01700	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A7B19_RS01705	COG3940	Belongs to the glycosyl hydrolase 43 family
A7B19_RS01720	COG2271	Major facilitator Superfamily
A7B19_RS01740	COG1733	regulation of RNA biosynthetic process
A7B19_RS01760	COG2124	cytochrome p450
A7B19_RS01770	COG0523	cobalamin synthesis protein
A7B19_RS01780	COG0640	Transcriptional regulator
A7B19_RS01795	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A7B19_RS01805	COG2197	response regulator
A7B19_RS01810	COG4585	Histidine kinase
A7B19_RS01815	COG2409	Drug exporters of the RND superfamily
A7B19_RS01825	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
A7B19_RS01835	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS01860	COG2070	2-Nitropropane dioxygenase
A7B19_RS01870	COG1121	(ABC) transporter
A7B19_RS01875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7B19_RS01910	COG0477	Major facilitator Superfamily
A7B19_RS01935	COG3485	protocatechuate 3,4-dioxygenase
A7B19_RS01965	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A7B19_RS02000	COG0667	Aldo Keto reductase
A7B19_RS02015	COG3940	Belongs to the glycosyl hydrolase 43 family
A7B19_RS02045	COG0765	amino acid transport
A7B19_RS02050	COG1126	abc transporter atp-binding protein
A7B19_RS02065	COG3458	cephalosporin-C deacetylase activity
A7B19_RS02075	COG1132	(ABC) transporter
A7B19_RS02085	COG1301	dicarboxylic acid transport
A7B19_RS02100	COG1132	(ABC) transporter
A7B19_RS02115	COG1946	Acyl-CoA thioesterase
A7B19_RS02125	COG2018	Roadblock/LC7 domain
A7B19_RS02145	COG2226	methyltransferase
A7B19_RS02170	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A7B19_RS02220	COG0514	ATP-dependent DNA helicase (RecQ)
A7B19_RS02290	COG1940	carbohydrate kinase activity
A7B19_RS02310	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A7B19_RS02315	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A7B19_RS02325	COG1960	acyl-CoA dehydrogenase activity
A7B19_RS02350	COG0121	glutamine amidotransferase
A7B19_RS02355	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
A7B19_RS02380	COG1024	Enoyl-CoA hydratase
A7B19_RS02445	COG3119	arylsulfatase activity
A7B19_RS02455	COG0477	Major facilitator Superfamily
A7B19_RS02465	COG0842	Transport permease protein
A7B19_RS02465	COG1131	(ABC) transporter
A7B19_RS02465	COG1716	ATPase activity
A7B19_RS02475	COG3321	synthase
A7B19_RS02475	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS02475	COG0604	alcohol dehydrogenase
A7B19_RS02510	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
A7B19_RS02530	COG0446	pyridine nucleotide-disulphide oxidoreductase
A7B19_RS02530	COG0404	The glycine cleavage system catalyzes the degradation of glycine
A7B19_RS02550	COG0531	amino acid
A7B19_RS02565	COG2340	Cysteine-rich secretory protein family
A7B19_RS02580	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A7B19_RS02645	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
A7B19_RS02665	COG0596	Alpha beta hydrolase
A7B19_RS02680	COG3383	formate dehydrogenase (NAD+) activity
A7B19_RS02680	COG0243	molybdopterin cofactor binding
A7B19_RS02685	COG0437	4 iron, 4 sulfur cluster binding
A7B19_RS02710	COG0246	Mannitol dehydrogenase
A7B19_RS02715	COG2271	Major facilitator Superfamily
A7B19_RS02720	COG3012	SEC-C Motif Domain Protein
A7B19_RS02745	COG0477	Major facilitator Superfamily
A7B19_RS02760	COG0508	dehydrogenase complex catalyzes the overall conversion of
A7B19_RS02765	COG0022	dehydrogenase e1 component
A7B19_RS02775	COG1522	sequence-specific DNA binding
A7B19_RS02785	COG0154	amidase activity
A7B19_RS02790	COG0473	3-isopropylmalate dehydrogenase activity
A7B19_RS02800	COG0601	transmembrane transport
A7B19_RS02805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A7B19_RS02820	COG1012	belongs to the aldehyde dehydrogenase family
A7B19_RS02825	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS02840	COG1262	PFAM Formylglycine-generating sulfatase enzyme
A7B19_RS02865	COG0673	inositol 2-dehydrogenase activity
A7B19_RS02870	COG0673	inositol 2-dehydrogenase activity
A7B19_RS02875	COG0673	inositol 2-dehydrogenase activity
A7B19_RS02885	COG0667	Aldo Keto reductase
A7B19_RS02905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A7B19_RS02910	COG4172	Belongs to the ABC transporter superfamily
A7B19_RS02940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A7B19_RS02950	COG0477	Major facilitator Superfamily
A7B19_RS02965	COG0747	negative chemotaxis
A7B19_RS02970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A7B19_RS02980	COG4172	Belongs to the ABC transporter superfamily
A7B19_RS02985	COG2175	clavaminate synthase activity
A7B19_RS02990	COG2175	clavaminate synthase activity
A7B19_RS03020	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A7B19_RS03040	COG0436	Aminotransferase
A7B19_RS03045	COG4221	oxidoreductase activity
A7B19_RS03065	COG0477	Major facilitator Superfamily
A7B19_RS03070	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
A7B19_RS03125	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS03135	COG0069	glutamate synthase activity
A7B19_RS03160	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
A7B19_RS03175	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A7B19_RS03190	COG4221	oxidoreductase activity
A7B19_RS03200	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
A7B19_RS03205	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
A7B19_RS03220	COG2080	2 iron, 2 sulfur cluster binding
A7B19_RS03225	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
A7B19_RS03230	COG1529	Aldehyde oxidase and xanthine dehydrogenase
A7B19_RS03255	COG1215	transferase activity, transferring glycosyl groups
A7B19_RS03315	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A7B19_RS03320	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A7B19_RS03325	COG2271	Major facilitator Superfamily
A7B19_RS03340	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A7B19_RS03410	COG0604	alcohol dehydrogenase
A7B19_RS03410	COG3321	synthase
A7B19_RS03415	COG0604	alcohol dehydrogenase
A7B19_RS03415	COG3321	synthase
A7B19_RS03420	COG0604	alcohol dehydrogenase
A7B19_RS03420	COG3321	synthase
A7B19_RS03450	COG2936	dipeptidyl-peptidase activity
A7B19_RS03455	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
A7B19_RS03465	COG0542	response to heat
A7B19_RS03490	COG1595	DNA-templated transcription, initiation
A7B19_RS03495	COG1252	NADH dehydrogenase
A7B19_RS03505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A7B19_RS03575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A7B19_RS03585	COG2313	pseudouridylate synthase activity
A7B19_RS03590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A7B19_RS03590	COG1522	sequence-specific DNA binding
A7B19_RS03685	COG3511	phospholipase C
A7B19_RS03695	COG2080	2 iron, 2 sulfur cluster binding
A7B19_RS03695	COG1529	Aldehyde oxidase and xanthine dehydrogenase
A7B19_RS03730	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A7B19_RS03770	COG1653	transport
A7B19_RS03780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A7B19_RS03790	COG0667	Aldo Keto reductase
A7B19_RS03795	COG1012	belongs to the aldehyde dehydrogenase family
A7B19_RS03820	COG3842	ATPase activity
A7B19_RS03830	COG3608	succinylglutamate desuccinylase aspartoacylase
A7B19_RS03835	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A7B19_RS03840	COG1414	Transcriptional regulator
A7B19_RS03845	COG3507	Belongs to the glycosyl hydrolase 43 family
A7B19_RS03850	COG0583	DNA-binding transcription factor activity
A7B19_RS03880	COG2211	Major facilitator Superfamily
A7B19_RS03890	COG1609	Transcriptional regulator
A7B19_RS03905	COG0395	ABC-type sugar transport system, permease component
A7B19_RS03910	COG3250	beta-galactosidase activity
A7B19_RS03915	COG0395	ABC-type sugar transport system, permease component
A7B19_RS03920	COG1175	transmembrane transport
A7B19_RS03935	COG1486	melibiose metabolic process
A7B19_RS03955	COG1357	PFAM Pentapeptide repeats (8 copies)
A7B19_RS03975	COG2197	response regulator
A7B19_RS03990	COG0583	DNA-binding transcription factor activity
A7B19_RS04000	COG2175	clavaminate synthase activity
A7B19_RS04005	COG3903	Transcriptional regulator
A7B19_RS04005	COG3629	intracellular signal transduction
A7B19_RS04020	COG2267	carboxylic ester hydrolase activity
A7B19_RS04030	COG0726	polysaccharide deacetylase
A7B19_RS04040	COG0300	oxidoreductase activity
A7B19_RS04055	COG0596	Alpha beta hydrolase
A7B19_RS04060	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A7B19_RS04075	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
A7B19_RS04085	COG2271	Major facilitator Superfamily
A7B19_RS04090	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A7B19_RS04100	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
A7B19_RS04115	COG2376	Dihydroxyacetone kinase
A7B19_RS04120	COG2376	Dihydroxyacetone kinase
A7B19_RS04125	COG3594	Acyltransferase
A7B19_RS04150	COG1529	Aldehyde oxidase and xanthine dehydrogenase
A7B19_RS04155	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
A7B19_RS04160	COG2080	2 iron, 2 sulfur cluster binding
A7B19_RS04165	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
A7B19_RS04200	COG1335	isochorismatase
A7B19_RS04205	COG3250	beta-galactosidase activity
A7B19_RS04235	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7B19_RS04240	COG1120	ATPase activity
A7B19_RS04265	COG0697	spore germination
A7B19_RS04275	COG0248	Ppx GppA phosphatase
A7B19_RS04290	COG0326	Molecular chaperone. Has ATPase activity
A7B19_RS04295	COG0596	Alpha beta hydrolase
A7B19_RS04320	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
A7B19_RS04335	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A7B19_RS04340	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A7B19_RS04350	COG2508	Transcriptional regulator
A7B19_RS04365	COG0739	heme binding
A7B19_RS04380	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A7B19_RS04395	COG1609	Transcriptional regulator
A7B19_RS04400	COG0366	Alpha amylase catalytic
A7B19_RS04410	COG0668	transmembrane transport
A7B19_RS04430	COG1609	Transcriptional regulator
A7B19_RS04440	COG1070	Carbohydrate kinase
A7B19_RS04455	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
A7B19_RS04460	COG3938	Belongs to the proline racemase family
A7B19_RS04470	COG0446	pyridine nucleotide-disulphide oxidoreductase
A7B19_RS04480	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A7B19_RS04495	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
A7B19_RS04495	COG2124	cytochrome p450
A7B19_RS04515	COG1609	Transcriptional regulator
A7B19_RS04525	COG4948	Mandelate Racemase Muconate Lactonizing
A7B19_RS04530	COG0246	Mannitol dehydrogenase
A7B19_RS04535	COG0477	Major facilitator Superfamily
A7B19_RS04540	COG1064	alcohol dehydrogenase
A7B19_RS04580	COG1309	transcriptional regulator
A7B19_RS04625	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
A7B19_RS04640	COG0281	malic enzyme
A7B19_RS04645	COG0679	Auxin Efflux Carrier
A7B19_RS04650	COG1968	undecaprenyl-diphosphatase activity
A7B19_RS04655	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
A7B19_RS04660	COG1228	amidohydrolase
A7B19_RS04700	COG2610	gluconate transmembrane transporter activity
A7B19_RS04720	COG1414	Transcriptional regulator
A7B19_RS04725	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
A7B19_RS04735	COG4948	Mandelate Racemase Muconate Lactonizing
A7B19_RS04755	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A7B19_RS04760	COG0531	amino acid
A7B19_RS04780	COG0326	Molecular chaperone. Has ATPase activity
A7B19_RS04790	COG1175	transmembrane transport
A7B19_RS04800	COG2197	response regulator
A7B19_RS04805	COG4585	Histidine kinase
A7B19_RS04850	COG2340	Cysteine-rich secretory protein family
A7B19_RS04870	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A7B19_RS04915	COG4213	ABC transporter substrate-binding protein
A7B19_RS04925	COG4214	carbohydrate transport
A7B19_RS04950	COG2197	response regulator
A7B19_RS04955	COG4585	Histidine kinase
A7B19_RS04985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A7B19_RS05010	COG1609	Transcriptional regulator
A7B19_RS05025	COG0531	amino acid
A7B19_RS05030	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
A7B19_RS05045	COG2197	response regulator
A7B19_RS05060	COG0577	efflux transmembrane transporter activity
A7B19_RS05060	COG1136	(ABC) transporter
A7B19_RS05070	COG2197	response regulator
A7B19_RS05075	COG4585	Histidine kinase
A7B19_RS05080	COG0577	efflux transmembrane transporter activity
A7B19_RS05085	COG3387	PFAM Glycoside hydrolase 15-related
A7B19_RS05095	COG1366	Belongs to the anti-sigma-factor antagonist family
A7B19_RS05095	COG2208	phosphoserine phosphatase activity
A7B19_RS05095	COG2172	sigma factor antagonist activity
A7B19_RS05120	COG1063	alcohol dehydrogenase
A7B19_RS05165	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
A7B19_RS05175	COG0492	ferredoxin-NADP+ reductase activity
A7B19_RS05185	COG3971	2-oxopent-4-enoate hydratase activity
A7B19_RS05190	COG4569	acetaldehyde dehydrogenase (acetylating) activity
A7B19_RS05195	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A7B19_RS05215	COG0673	inositol 2-dehydrogenase activity
A7B19_RS05225	COG0747	negative chemotaxis
A7B19_RS05235	COG0444	Belongs to the ABC transporter superfamily
A7B19_RS05245	COG0604	alcohol dehydrogenase
A7B19_RS05245	COG3321	synthase
A7B19_RS05280	COG1175	transmembrane transport
A7B19_RS05285	COG0395	ABC-type sugar transport system, permease component
A7B19_RS05290	COG1609	Transcriptional regulator
A7B19_RS05295	COG0395	ABC-type sugar transport system, permease component
A7B19_RS05300	COG1175	transmembrane transport
A7B19_RS05310	COG1609	Transcriptional regulator
A7B19_RS05315	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A7B19_RS05350	COG0477	Major facilitator Superfamily
A7B19_RS05365	COG3046	protein related to deoxyribodipyrimidine photolyase
A7B19_RS05375	COG4221	oxidoreductase activity
A7B19_RS05385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A7B19_RS05400	COG3290	protein histidine kinase activity
A7B19_RS05405	COG0701	Predicted permease
A7B19_RS05445	COG1082	Xylose isomerase domain protein TIM barrel
A7B19_RS05445	COG3185	4-Hydroxyphenylpyruvate dioxygenase
A7B19_RS05450	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A7B19_RS05475	COG0277	FAD linked oxidase domain protein
A7B19_RS05495	COG1819	glycosyl
A7B19_RS05505	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A7B19_RS05520	COG3619	membrane
A7B19_RS05525	COG1335	isochorismatase
A7B19_RS05530	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
A7B19_RS05550	COG4977	sequence-specific DNA binding
A7B19_RS05550	COG1917	Cupin 2, conserved barrel domain protein
A7B19_RS05600	COG4638	Rieske (2fe-2S)
A7B19_RS05615	COG0477	Major facilitator Superfamily
A7B19_RS05620	COG1414	Transcriptional regulator
A7B19_RS05645	COG4829	muconolactone delta-isomerase
A7B19_RS05650	COG3485	protocatechuate 3,4-dioxygenase
A7B19_RS05660	COG0583	DNA-binding transcription factor activity
A7B19_RS05665	COG4221	oxidoreductase activity
A7B19_RS05670	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
A7B19_RS05675	COG2706	6-phosphogluconolactonase activity
A7B19_RS05700	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
A7B19_RS05705	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
A7B19_RS05755	COG1100	Small GTP-binding protein
A7B19_RS05815	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A7B19_RS05825	COG3835	regulator
A7B19_RS05830	COG2353	YceI-like domain
A7B19_RS05845	COG5297	Belongs to the glycosyl hydrolase family 6
A7B19_RS05845	COG3250	beta-galactosidase activity
A7B19_RS05860	COG1653	transport
A7B19_RS05865	COG0395	ABC-type sugar transport system, permease component
A7B19_RS05875	COG1609	Transcriptional regulator
A7B19_RS05880	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A7B19_RS05900	COG2018	Roadblock/LC7 domain
A7B19_RS05915	COG0477	Major facilitator Superfamily
A7B19_RS05930	COG0604	alcohol dehydrogenase
A7B19_RS05930	COG3321	synthase
A7B19_RS05930	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS05940	COG0667	Aldo Keto reductase
A7B19_RS05945	COG1309	transcriptional regulator
A7B19_RS05950	COG3321	synthase
A7B19_RS05950	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS05950	COG0604	alcohol dehydrogenase
A7B19_RS05965	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS05970	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A7B19_RS06000	COG0667	Aldo Keto reductase
A7B19_RS06010	COG3507	Belongs to the glycosyl hydrolase 43 family
A7B19_RS06015	COG3250	beta-galactosidase activity
A7B19_RS06035	COG0318	PFAM AMP-dependent synthetase and ligase
A7B19_RS06055	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
A7B19_RS06060	COG3708	Transcriptional regulator
A7B19_RS06060	COG2207	Transcriptional regulator
A7B19_RS06120	COG2391	methyltransferase activity
A7B19_RS06125	COG0154	amidase activity
A7B19_RS06130	COG0698	ribose 5-phosphate isomerase
A7B19_RS06135	COG2376	Dihydroxyacetone kinase
A7B19_RS06140	COG1070	Carbohydrate kinase
A7B19_RS06150	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A7B19_RS06160	COG2814	Major facilitator Superfamily
A7B19_RS06190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A7B19_RS06205	COG1609	Transcriptional regulator
A7B19_RS06210	COG2814	Major facilitator Superfamily
A7B19_RS06215	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
A7B19_RS06240	COG3321	synthase
A7B19_RS06240	COG0604	alcohol dehydrogenase
A7B19_RS06245	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A7B19_RS06245	COG2022	thiamine diphosphate biosynthetic process
A7B19_RS06260	COG0604	alcohol dehydrogenase
A7B19_RS06260	COG3321	synthase
A7B19_RS06290	COG0477	Major facilitator Superfamily
A7B19_RS06295	COG2124	cytochrome p450
A7B19_RS06300	COG0604	alcohol dehydrogenase
A7B19_RS06300	COG3321	synthase
A7B19_RS06305	COG2267	carboxylic ester hydrolase activity
A7B19_RS06310	COG0604	alcohol dehydrogenase
A7B19_RS06310	COG3321	synthase
A7B19_RS06315	COG3321	synthase
A7B19_RS06315	COG0604	alcohol dehydrogenase
A7B19_RS06340	COG0402	S-adenosylhomocysteine deaminase activity
A7B19_RS06365	COG4249	Peptidase C14 caspase catalytic subunit p20
A7B19_RS06365	COG2319	Wd-40 repeat
A7B19_RS06405	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS06415	COG2072	flavoprotein involved in K transport
A7B19_RS06430	COG2223	nitrite transmembrane transporter activity
A7B19_RS06435	COG2207	Transcriptional regulator
A7B19_RS06440	COG3973	AAA domain
A7B19_RS06450	COG0747	negative chemotaxis
A7B19_RS06460	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A7B19_RS06480	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
A7B19_RS06495	COG0477	Major facilitator Superfamily
A7B19_RS06530	COG0601	transmembrane transport
A7B19_RS06535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A7B19_RS06550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A7B19_RS06555	COG2072	flavoprotein involved in K transport
A7B19_RS06565	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS06585	COG1804	L-carnitine dehydratase bile acid-inducible protein F
A7B19_RS06625	COG0444	Belongs to the ABC transporter superfamily
A7B19_RS06635	COG4608	Belongs to the ABC transporter superfamily
A7B19_RS06645	COG1024	Enoyl-CoA hydratase
A7B19_RS06655	COG0183	Belongs to the thiolase family
A7B19_RS06660	COG1960	acyl-CoA dehydrogenase activity
A7B19_RS06675	COG1804	L-carnitine dehydratase bile acid-inducible protein F
A7B19_RS06680	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS06730	COG1129	ABC transporter
A7B19_RS06735	COG3284	Transcriptional regulator
A7B19_RS06770	COG4585	Histidine kinase
A7B19_RS06775	COG2197	response regulator
A7B19_RS06795	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A7B19_RS06795	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A7B19_RS06825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A7B19_RS06835	COG1397	ADP-ribosylglycohydrolase
A7B19_RS06840	COG2188	Transcriptional regulator
A7B19_RS06845	COG0006	proline dipeptidase activity
A7B19_RS06880	COG0235	Class ii aldolase
A7B19_RS06885	COG3395	kinase activity
A7B19_RS06890	COG0473	3-isopropylmalate dehydrogenase activity
A7B19_RS06905	COG2851	Citrate transporter
A7B19_RS06920	COG0395	ABC-type sugar transport system, permease component
A7B19_RS06940	COG2226	methyltransferase
A7B19_RS06975	COG1064	alcohol dehydrogenase
A7B19_RS06990	COG0583	DNA-binding transcription factor activity
A7B19_RS06995	COG1804	L-carnitine dehydratase bile acid-inducible protein F
A7B19_RS07000	COG1960	acyl-CoA dehydrogenase activity
A7B19_RS07005	COG0488	(ABC) transporter
A7B19_RS07010	COG0596	Alpha beta hydrolase
A7B19_RS07020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A7B19_RS07025	COG2124	cytochrome p450
A7B19_RS07035	COG3525	Glycosyl hydrolase, family 20, catalytic domain
A7B19_RS07035	COG3291	Pkd domain containing protein
A7B19_RS07065	COG1733	regulation of RNA biosynthetic process
A7B19_RS07085	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A7B19_RS07090	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A7B19_RS07130	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A7B19_RS07135	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
A7B19_RS07140	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A7B19_RS07170	COG2169	Transcriptional regulator
A7B19_RS07215	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A7B19_RS07220	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A7B19_RS07245	COG2188	Transcriptional regulator
A7B19_RS07250	COG2814	Major facilitator Superfamily
A7B19_RS07270	COG2124	cytochrome p450
A7B19_RS07275	COG2124	cytochrome p450
A7B19_RS07300	COG2124	cytochrome p450
A7B19_RS07320	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A7B19_RS07325	COG3321	synthase
A7B19_RS07325	COG0300	oxidoreductase activity
A7B19_RS07325	COG0318	PFAM AMP-dependent synthetase and ligase
A7B19_RS07325	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A7B19_RS07325	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS07345	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS07350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A7B19_RS07370	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
A7B19_RS07385	COG2264	protein methyltransferase activity
A7B19_RS07405	COG0477	Major facilitator Superfamily
A7B19_RS07420	COG0702	epimerase
A7B19_RS07450	COG2814	Major facilitator Superfamily
A7B19_RS07460	COG1280	lysine exporter protein (LysE YggA)
A7B19_RS07470	COG2084	Dehydrogenase
A7B19_RS07475	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
A7B19_RS07485	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS07490	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS07500	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS07505	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A7B19_RS07520	COG0477	Major facilitator Superfamily
A7B19_RS07540	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
A7B19_RS07560	COG0640	Transcriptional regulator
A7B19_RS07565	COG1301	dicarboxylic acid transport
A7B19_RS07570	COG2828	Protein conserved in bacteria
A7B19_RS07580	COG0702	epimerase
A7B19_RS07600	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A7B19_RS07600	COG3320	Male sterility
A7B19_RS07605	COG3321	synthase
A7B19_RS07605	COG0604	alcohol dehydrogenase
A7B19_RS07610	COG3321	synthase
A7B19_RS07610	COG0604	alcohol dehydrogenase
A7B19_RS07620	COG2197	response regulator
A7B19_RS07640	COG1309	transcriptional regulator
A7B19_RS07685	COG0395	ABC-type sugar transport system, permease component
A7B19_RS07690	COG1175	transmembrane transport
A7B19_RS07700	COG1609	Transcriptional regulator
A7B19_RS07715	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
A7B19_RS07720	COG3104	oligopeptide transport
A7B19_RS07725	COG2084	Dehydrogenase
A7B19_RS07730	COG0583	DNA-binding transcription factor activity
A7B19_RS07765	COG1914	H( )-stimulated, divalent metal cation uptake system
A7B19_RS07770	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A7B19_RS07780	COG0667	Aldo Keto reductase
A7B19_RS07790	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
A7B19_RS07795	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
A7B19_RS07810	COG3250	beta-galactosidase activity
A7B19_RS07820	COG3591	Belongs to the peptidase S1B family
A7B19_RS07820	COG1864	DNA RNA non-specific endonuclease
A7B19_RS07830	COG0583	DNA-binding transcription factor activity
A7B19_RS07850	COG2031	fatty acid transporter
A7B19_RS07870	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A7B19_RS07890	COG0583	DNA-binding transcription factor activity
A7B19_RS07905	COG2814	Major facilitator Superfamily
A7B19_RS07915	COG0151	Belongs to the GarS family
A7B19_RS07925	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A7B19_RS07930	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
A7B19_RS07950	COG0367	asparagine synthase
A7B19_RS07975	COG0438	transferase activity, transferring glycosyl groups
A7B19_RS07985	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
A7B19_RS08000	COG4310	Domain of unknown function (DUF2172)
A7B19_RS08010	COG1215	transferase activity, transferring glycosyl groups
A7B19_RS08025	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
A7B19_RS08045	COG2018	Roadblock/LC7 domain
A7B19_RS08065	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS08070	COG0583	DNA-binding transcription factor activity
A7B19_RS08085	COG0531	amino acid
A7B19_RS08100	COG0071	Belongs to the small heat shock protein (HSP20) family
A7B19_RS08120	COG0542	response to heat
A7B19_RS08135	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
A7B19_RS08140	COG0443	Heat shock 70 kDa protein
A7B19_RS08195	COG3693	PFAM glycoside hydrolase, family 10
A7B19_RS08225	COG0477	Major facilitator Superfamily
A7B19_RS08230	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
A7B19_RS08235	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
A7B19_RS08250	COG3971	2-oxopent-4-enoate hydratase activity
A7B19_RS08260	COG2272	Belongs to the type-B carboxylesterase lipase family
A7B19_RS08270	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
A7B19_RS08300	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS08310	COG1309	transcriptional regulator
A7B19_RS08320	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A7B19_RS08330	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A7B19_RS08335	COG2814	Major facilitator Superfamily
A7B19_RS08345	COG0179	Fumarylacetoacetate (FAA) hydrolase
A7B19_RS08350	COG1802	Transcriptional regulator
A7B19_RS08360	COG1309	transcriptional regulator
A7B19_RS08370	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A7B19_RS08400	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS08410	COG1063	alcohol dehydrogenase
A7B19_RS08420	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
A7B19_RS08435	COG2315	Protein conserved in bacteria
A7B19_RS08440	COG2315	Protein conserved in bacteria
A7B19_RS08445	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A7B19_RS08490	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
A7B19_RS08505	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A7B19_RS08515	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A7B19_RS08525	COG2124	cytochrome p450
A7B19_RS08530	COG2070	2-Nitropropane dioxygenase
A7B19_RS08530	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A7B19_RS08535	COG0318	PFAM AMP-dependent synthetase and ligase
A7B19_RS08535	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS08535	COG3321	synthase
A7B19_RS08535	COG0300	oxidoreductase activity
A7B19_RS08535	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A7B19_RS08550	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A7B19_RS08555	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A7B19_RS08555	COG0300	oxidoreductase activity
A7B19_RS08555	COG4221	oxidoreductase activity
A7B19_RS08555	COG4221	oxidoreductase activity
A7B19_RS08555	COG3321	synthase
A7B19_RS08555	COG3321	synthase
A7B19_RS08555	COG0300	oxidoreductase activity
A7B19_RS08555	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A7B19_RS08600	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
A7B19_RS08700	COG0513	Belongs to the DEAD box helicase family
A7B19_RS08710	COG1960	acyl-CoA dehydrogenase activity
A7B19_RS08715	COG0183	Belongs to the thiolase family
A7B19_RS08720	COG0318	PFAM AMP-dependent synthetase and ligase
A7B19_RS08725	COG1804	L-carnitine dehydratase bile acid-inducible protein F
A7B19_RS08730	COG1024	Enoyl-CoA hydratase
A7B19_RS08740	COG3226	Transcriptional regulator
A7B19_RS08755	COG0559	Belongs to the binding-protein-dependent transport system permease family
A7B19_RS08770	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A7B19_RS08780	COG2267	carboxylic ester hydrolase activity
A7B19_RS08785	COG3321	synthase
A7B19_RS08785	COG0604	alcohol dehydrogenase
A7B19_RS08790	COG0667	Aldo Keto reductase
A7B19_RS08820	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
A7B19_RS08830	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
A7B19_RS08835	COG2218	PFAM glutamate synthase alpha subunit domain protein
A7B19_RS08845	COG0069	glutamate synthase activity
A7B19_RS08850	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A7B19_RS08865	COG1309	transcriptional regulator
A7B19_RS08920	COG0477	Major facilitator Superfamily
A7B19_RS08945	COG1012	belongs to the aldehyde dehydrogenase family
A7B19_RS08955	COG1454	alcohol dehydrogenase
A7B19_RS08965	COG2508	Transcriptional regulator
A7B19_RS08970	COG3268	Saccharopine dehydrogenase
A7B19_RS08985	COG0179	Fumarylacetoacetate (FAA) hydrolase
A7B19_RS08995	COG1881	PFAM PEBP family protein
A7B19_RS09015	COG0723	plastoquinol--plastocyanin reductase activity
A7B19_RS09020	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
A7B19_RS09040	COG2207	Transcriptional regulator
A7B19_RS09055	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A7B19_RS09065	COG2130	NADP-dependent
A7B19_RS09110	COG2070	2-Nitropropane dioxygenase
A7B19_RS09115	COG0657	acetylesterase activity
A7B19_RS09125	COG0583	DNA-binding transcription factor activity
A7B19_RS09160	COG3547	Transposase (IS116 IS110 IS902 family)
A7B19_RS09165	COG0583	DNA-binding transcription factor activity
A7B19_RS09180	COG0604	alcohol dehydrogenase
A7B19_RS09195	COG0583	DNA-binding transcription factor activity
A7B19_RS09210	COG0346	lactoylglutathione lyase activity
A7B19_RS09215	COG0640	Transcriptional regulator
A7B19_RS09235	COG2409	Drug exporters of the RND superfamily
A7B19_RS09250	COG2267	carboxylic ester hydrolase activity
A7B19_RS09270	COG0778	Nitroreductase
A7B19_RS09275	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS09325	COG0789	Transcriptional regulator
A7B19_RS09330	COG3959	Transketolase, thiamine diphosphate binding domain
A7B19_RS09335	COG3958	Transketolase
A7B19_RS09340	COG2267	carboxylic ester hydrolase activity
A7B19_RS09370	COG4175	Glycine betaine
A7B19_RS09370	COG0517	IMP dehydrogenase activity
A7B19_RS09375	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A7B19_RS09400	COG0805	protein transport
A7B19_RS09405	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A7B19_RS09425	COG2378	regulation of single-species biofilm formation
A7B19_RS09435	COG0545	Peptidyl-prolyl cis-trans isomerase
A7B19_RS09440	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
A7B19_RS09455	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
A7B19_RS09460	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
A7B19_RS09470	COG4122	O-methyltransferase activity
A7B19_RS09475	COG1222	aaa ATPase
A7B19_RS09490	COG1994	Peptidase M50
A7B19_RS09490	COG0517	IMP dehydrogenase activity
A7B19_RS09500	COG2197	response regulator
A7B19_RS09515	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A7B19_RS09520	COG1410	methionine synthase
A7B19_RS09520	COG0646	methionine synthase
A7B19_RS09525	COG1414	Transcriptional regulator
A7B19_RS09530	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
A7B19_RS09535	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
A7B19_RS09540	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
A7B19_RS09555	COG3618	amidohydrolase
A7B19_RS09565	COG4211	Belongs to the binding-protein-dependent transport system permease family
A7B19_RS09580	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS09585	COG4948	Mandelate Racemase Muconate Lactonizing
A7B19_RS09595	COG0215	cysteine-tRNA ligase activity
A7B19_RS09610	COG0406	alpha-ribazole phosphatase activity
A7B19_RS09615	COG0598	Magnesium transport protein CorA
A7B19_RS09625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A7B19_RS09630	COG0667	Aldo Keto reductase
A7B19_RS09650	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A7B19_RS09695	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A7B19_RS09700	COG2080	2 iron, 2 sulfur cluster binding
A7B19_RS09705	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
A7B19_RS09710	COG1529	Aldehyde oxidase and xanthine dehydrogenase
A7B19_RS09715	COG0702	epimerase
A7B19_RS09725	COG0438	transferase activity, transferring glycosyl groups
A7B19_RS09760	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
A7B19_RS09765	COG2149	membrane
A7B19_RS09785	COG1733	regulation of RNA biosynthetic process
A7B19_RS09795	COG1960	acyl-CoA dehydrogenase activity
A7B19_RS09805	COG0318	PFAM AMP-dependent synthetase and ligase
A7B19_RS09855	COG2851	Citrate transporter
A7B19_RS09860	COG3383	formate dehydrogenase (NAD+) activity
A7B19_RS09865	COG1309	transcriptional regulator
A7B19_RS09870	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
A7B19_RS09875	COG2188	Transcriptional regulator
A7B19_RS09910	COG0515	serine threonine protein kinase
A7B19_RS09930	COG0463	Glycosyl transferase, family 2
A7B19_RS09960	COG1834	amidinotransferase
A7B19_RS09965	COG1725	Transcriptional regulator
A7B19_RS09980	COG2226	methyltransferase
A7B19_RS09995	COG1609	Transcriptional regulator
A7B19_RS10000	COG0019	diaminopimelate decarboxylase activity
A7B19_RS10005	COG4264	IucA IucC family
A7B19_RS10055	COG1846	Transcriptional regulator
A7B19_RS10060	COG1764	response to oxidative stress
A7B19_RS10065	COG1280	lysine exporter protein (LysE YggA)
A7B19_RS10075	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A7B19_RS10080	COG0587	DNA-directed DNA polymerase activity
A7B19_RS10085	COG3467	pyridoxamine 5'-phosphate
A7B19_RS10100	COG0330	HflC and HflK could
A7B19_RS10110	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A7B19_RS10115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A7B19_RS10120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A7B19_RS10125	COG1126	abc transporter atp-binding protein
A7B19_RS10145	COG1799	cell septum assembly
A7B19_RS10150	COG1960	acyl-CoA dehydrogenase activity
A7B19_RS10155	COG0477	Major facilitator Superfamily
A7B19_RS10165	COG0671	phosphoesterase, PA-phosphatase related
A7B19_RS10215	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A7B19_RS10230	COG0438	transferase activity, transferring glycosyl groups
A7B19_RS10245	COG1160	GTP binding
A7B19_RS10255	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
A7B19_RS10275	COG1187	pseudouridine synthase activity
A7B19_RS10280	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
A7B19_RS10285	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
A7B19_RS10300	COG0686	Belongs to the AlaDH PNT family
A7B19_RS10310	COG0494	nUDIX hydrolase
A7B19_RS10315	COG0504	CTP synthase activity
A7B19_RS10320	COG3387	PFAM Glycoside hydrolase 15-related
A7B19_RS10340	COG0297	glycogen (starch) synthase activity
A7B19_RS10345	COG0497	DNA recombination
A7B19_RS10350	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
A7B19_RS10370	COG1120	ATPase activity
A7B19_RS10375	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7B19_RS10380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7B19_RS10385	COG0647	UMP catabolic process
A7B19_RS10420	COG2094	Belongs to the DNA glycosylase MPG family
A7B19_RS10435	COG1881	PFAM PEBP family protein
A7B19_RS10455	COG1119	ATPase activity
A7B19_RS10470	COG2197	response regulator
A7B19_RS10485	COG1716	ATPase activity
A7B19_RS10485	COG0842	Transport permease protein
A7B19_RS10485	COG1131	(ABC) transporter
A7B19_RS10490	COG3830	Belongs to the UPF0237 family
A7B19_RS10490	COG0560	Phosphoserine phosphatase
A7B19_RS10505	COG2807	transmembrane transport
A7B19_RS10510	COG2186	Transcriptional regulator
A7B19_RS10520	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
A7B19_RS10525	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS10565	COG1902	pentaerythritol trinitrate reductase activity
A7B19_RS10575	COG2807	transmembrane transport
A7B19_RS10595	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
A7B19_RS10615	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A7B19_RS10620	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A7B19_RS10665	COG3387	PFAM Glycoside hydrolase 15-related
A7B19_RS10720	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS10725	COG1846	Transcriptional regulator
A7B19_RS10755	COG1024	Enoyl-CoA hydratase
A7B19_RS10765	COG0488	(ABC) transporter
A7B19_RS10780	COG0235	Class ii aldolase
A7B19_RS10795	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
A7B19_RS10800	COG1492	cobalamin metabolic process
A7B19_RS10815	COG1797	cobyrinic acid a,c-diamide synthase activity
A7B19_RS10855	COG0456	acetyltransferase
A7B19_RS10865	COG1917	Cupin 2, conserved barrel domain protein
A7B19_RS10870	COG5285	phytanoyl-CoA dioxygenase
A7B19_RS10885	COG1414	Transcriptional regulator
A7B19_RS10895	COG4585	Histidine kinase
A7B19_RS10905	COG0667	Aldo Keto reductase
A7B19_RS10915	COG3866	Pectate lyase
A7B19_RS10920	COG2755	lipolytic protein G-D-S-L family
A7B19_RS10930	COG4677	pectinesterase activity
A7B19_RS10955	COG0395	ABC-type sugar transport system, permease component
A7B19_RS10975	COG1802	Transcriptional regulator
A7B19_RS11010	COG0714	Associated with various cellular activities
A7B19_RS11035	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A7B19_RS11040	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A7B19_RS11055	COG3467	pyridoxamine 5'-phosphate
A7B19_RS11075	COG1175	transmembrane transport
A7B19_RS11080	COG1653	transport
A7B19_RS11085	COG4948	Mandelate Racemase Muconate Lactonizing
A7B19_RS11090	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A7B19_RS11095	COG0583	DNA-binding transcription factor activity
A7B19_RS11100	COG0110	maltose O-acetyltransferase activity
A7B19_RS11130	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A7B19_RS11155	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
A7B19_RS11165	COG1335	isochorismatase
A7B19_RS11170	COG0477	Major facilitator Superfamily
A7B19_RS11175	COG1846	Transcriptional regulator
A7B19_RS11180	COG2409	Drug exporters of the RND superfamily
A7B19_RS11185	COG2814	Major facilitator Superfamily
A7B19_RS11190	COG1846	Transcriptional regulator
A7B19_RS11230	COG1063	alcohol dehydrogenase
A7B19_RS11290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A7B19_RS11310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A7B19_RS11395	COG2171	N-acyltransferase activity
A7B19_RS11400	COG3226	Transcriptional regulator
A7B19_RS11405	COG2076	Multidrug Resistance protein
A7B19_RS11410	COG2151	metal-sulfur cluster biosynthetic enzyme
A7B19_RS11415	COG0822	iron-sulfur transferase activity
A7B19_RS11420	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A7B19_RS11425	COG0396	ATPase activity
A7B19_RS11435	COG0719	Fe-S assembly protein
A7B19_RS11460	COG1612	heme a metabolic process
A7B19_RS11475	COG0109	protoheme IX farnesyltransferase activity
A7B19_RS11480	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
A7B19_RS11485	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A7B19_RS11505	COG0166	Belongs to the GPI family
A7B19_RS11520	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A7B19_RS11525	COG0149	triose-phosphate isomerase activity
A7B19_RS11530	COG0126	phosphoglycerate kinase activity
A7B19_RS11535	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A7B19_RS11545	COG1481	regulation of sporulation
A7B19_RS11555	COG1660	Displays ATPase and GTPase activities
A7B19_RS11560	COG0322	excinuclease ABC activity
A7B19_RS11580	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
A7B19_RS11590	COG0477	Major facilitator Superfamily
A7B19_RS11610	COG0556	nucleotide-excision repair
A7B19_RS11615	COG0584	glycerophosphoryl diester phosphodiesterase
A7B19_RS11620	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A7B19_RS11670	COG0237	dephospho-CoA kinase activity
A7B19_RS11680	COG0539	negative regulation of cytoplasmic translation
A7B19_RS11690	COG1643	Atp-dependent helicase
A7B19_RS11725	COG2050	protein possibly involved in aromatic compounds catabolism
A7B19_RS11745	COG0411	ABC transporter
A7B19_RS11780	COG0737	Belongs to the 5'-nucleotidase family
A7B19_RS11800	COG1605	Chorismate mutase
A7B19_RS11800	COG0287	Prephenate dehydrogenase
A7B19_RS11815	COG3467	pyridoxamine 5'-phosphate
A7B19_RS11820	COG1131	(ABC) transporter
A7B19_RS11825	COG1725	Transcriptional regulator
A7B19_RS11835	COG0067	glutamate synthase
A7B19_RS11835	COG0069	glutamate synthase activity
A7B19_RS11835	COG0070	glutamate synthase
A7B19_RS11855	COG0159	tryptophan synthase activity
A7B19_RS11860	COG0133	tryptophan synthase activity
A7B19_RS11865	COG0134	indole-3-glycerol-phosphate synthase activity
A7B19_RS11890	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
A7B19_RS11905	COG2076	Multidrug Resistance protein
A7B19_RS11915	COG1609	Transcriptional regulator
A7B19_RS11920	COG0673	inositol 2-dehydrogenase activity
A7B19_RS11935	COG1902	pentaerythritol trinitrate reductase activity
A7B19_RS11940	COG0789	Transcriptional regulator
A7B19_RS11955	COG0107	imidazoleglycerol-phosphate synthase activity
A7B19_RS11960	COG0251	oxidation-reduction process
A7B19_RS11965	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
A7B19_RS11970	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
A7B19_RS11975	COG0131	Imidazoleglycerol-phosphate dehydratase
A7B19_RS11980	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A7B19_RS11985	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
A7B19_RS11995	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
A7B19_RS12000	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A7B19_RS12015	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS12030	COG0252	asparaginase activity
A7B19_RS12035	COG1609	Transcriptional regulator
A7B19_RS12055	COG1432	Conserved Protein
A7B19_RS12060	COG0587	DNA-directed DNA polymerase activity
A7B19_RS12105	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
A7B19_RS12115	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
A7B19_RS12120	COG3599	regulation of cell shape
A7B19_RS12130	COG1799	cell septum assembly
A7B19_RS12145	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A7B19_RS12150	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
A7B19_RS12155	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
A7B19_RS12165	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
A7B19_RS12170	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A7B19_RS12185	COG0768	penicillin binding
A7B19_RS12195	COG0275	rRNA processing
A7B19_RS12205	COG0714	Associated with various cellular activities
A7B19_RS12240	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
A7B19_RS12250	COG1309	transcriptional regulator
A7B19_RS12270	COG0352	thiamine-phosphate diphosphorylase activity
A7B19_RS12280	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A7B19_RS12285	COG2022	thiamine diphosphate biosynthetic process
A7B19_RS12285	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A7B19_RS12295	COG2022	thiamine diphosphate biosynthetic process
A7B19_RS12305	COG2815	serine threonine protein kinase
A7B19_RS12305	COG0515	serine threonine protein kinase
A7B19_RS12310	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
A7B19_RS12325	COG3479	Phenolic acid decarboxylase
A7B19_RS12330	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
A7B19_RS12335	COG2193	ferroxidase activity
A7B19_RS12340	COG0243	molybdopterin cofactor binding
A7B19_RS12345	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
A7B19_RS12370	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A7B19_RS12390	COG0477	Major facilitator Superfamily
A7B19_RS12400	COG0205	6-phosphofructokinase activity
A7B19_RS12405	COG2197	response regulator
A7B19_RS12435	COG1940	carbohydrate kinase activity
A7B19_RS12445	COG0003	Pfam Anion-transporting ATPase
A7B19_RS12505	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A7B19_RS12510	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A7B19_RS12515	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
A7B19_RS12520	COG0723	plastoquinol--plastocyanin reductase activity
A7B19_RS12525	COG2010	Cytochrome c
A7B19_RS12530	COG1845	cytochrome c oxidase, subunit III
A7B19_RS12540	COG1376	ErfK ybiS ycfS ynhG family protein
A7B19_RS12550	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A7B19_RS12555	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
A7B19_RS12565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A7B19_RS12585	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
A7B19_RS12590	COG2197	response regulator
A7B19_RS12595	COG4585	Histidine kinase
A7B19_RS12630	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
A7B19_RS12640	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
A7B19_RS12645	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
A7B19_RS12650	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A7B19_RS12655	COG0508	dehydrogenase complex catalyzes the overall conversion of
A7B19_RS12665	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
A7B19_RS12675	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS12710	COG0640	Transcriptional regulator
A7B19_RS12720	COG0321	lipoyl(octanoyl) transferase activity
A7B19_RS12725	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
A7B19_RS12755	COG4585	Histidine kinase
A7B19_RS12775	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
A7B19_RS12800	COG0477	Major facilitator Superfamily
A7B19_RS12820	COG0745	RESPONSE REGULATOR receiver
A7B19_RS12835	COG2197	response regulator
A7B19_RS12860	COG0395	ABC-type sugar transport system, permease component
A7B19_RS12870	COG2182	Extracellular solute-binding protein
A7B19_RS12875	COG0366	Alpha amylase catalytic
A7B19_RS12880	COG1609	Transcriptional regulator
A7B19_RS12890	COG0561	phosphatase activity
A7B19_RS12895	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
A7B19_RS12975	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
A7B19_RS12990	COG0589	response to stress
A7B19_RS12995	COG2814	Major facilitator Superfamily
A7B19_RS13000	COG1082	Xylose isomerase domain protein TIM barrel
A7B19_RS13005	COG1609	Transcriptional regulator
A7B19_RS13010	COG0174	glutamine synthetase
A7B19_RS13015	COG2132	Multicopper oxidase
A7B19_RS13020	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A7B19_RS13020	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
A7B19_RS13025	COG3795	YCII-related domain
A7B19_RS13030	COG4941	Belongs to the sigma-70 factor family
A7B19_RS13035	COG2267	carboxylic ester hydrolase activity
A7B19_RS13050	COG2814	Major facilitator Superfamily
A7B19_RS13060	COG1309	transcriptional regulator
A7B19_RS13065	COG0477	Major facilitator Superfamily
A7B19_RS13070	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
A7B19_RS13090	COG1994	Peptidase M50
A7B19_RS13110	COG0395	ABC-type sugar transport system, permease component
A7B19_RS13115	COG1175	transmembrane transport
A7B19_RS13135	COG0667	Aldo Keto reductase
A7B19_RS13155	COG0574	Belongs to the PEP-utilizing enzyme family
A7B19_RS13155	COG3848	Pyruvate phosphate dikinase
A7B19_RS13175	COG5398	heme oxygenase
A7B19_RS13180	COG1120	ATPase activity
A7B19_RS13185	COG2822	iron ion transport
A7B19_RS13190	COG2837	iron assimilation
A7B19_RS13195	COG0672	)-iron permease
A7B19_RS13225	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A7B19_RS13230	COG2814	Major facilitator Superfamily
A7B19_RS13240	COG3540	Alkaline phosphatase
A7B19_RS13245	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS13265	COG0583	DNA-binding transcription factor activity
A7B19_RS13275	COG0488	(ABC) transporter
A7B19_RS13280	COG2378	regulation of single-species biofilm formation
A7B19_RS13310	COG0583	DNA-binding transcription factor activity
A7B19_RS13325	COG4638	Rieske (2fe-2S)
A7B19_RS13330	COG1902	pentaerythritol trinitrate reductase activity
A7B19_RS13330	COG0446	pyridine nucleotide-disulphide oxidoreductase
A7B19_RS13715	COG4974	Belongs to the 'phage' integrase family
A7B19_RS13725	COG0366	Alpha amylase catalytic
A7B19_RS13730	COG3022	response to hydroperoxide
A7B19_RS13735	COG0800	Aldolase
A7B19_RS13750	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
A7B19_RS13775	COG2030	dehydratase
A7B19_RS13780	COG4585	Histidine kinase
A7B19_RS13785	COG2197	response regulator
A7B19_RS13815	COG1960	acyl-CoA dehydrogenase activity
A7B19_RS13825	COG0860	N-Acetylmuramoyl-L-alanine amidase
A7B19_RS13835	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A7B19_RS13855	COG0438	transferase activity, transferring glycosyl groups
A7B19_RS13860	COG1309	transcriptional regulator
A7B19_RS13865	COG2197	response regulator
A7B19_RS13910	COG4585	Histidine kinase
A7B19_RS13915	COG2197	response regulator
A7B19_RS13965	COG3845	ABC transporter
A7B19_RS14000	COG0183	Belongs to the thiolase family
A7B19_RS14005	COG2124	cytochrome p450
A7B19_RS14030	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
A7B19_RS14040	COG1733	regulation of RNA biosynthetic process
A7B19_RS14055	COG0010	Belongs to the arginase family
A7B19_RS14065	COG0745	RESPONSE REGULATOR receiver
A7B19_RS14070	COG2205	protein histidine kinase activity
A7B19_RS14180	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
A7B19_RS14200	COG0739	heme binding
A7B19_RS14200	COG1196	nuclear chromosome segregation
A7B19_RS14200	COG0741	lytic transglycosylase activity
A7B19_RS14230	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
A7B19_RS14250	COG2315	Protein conserved in bacteria
A7B19_RS14290	COG2201	protein-glutamate methylesterase activity
A7B19_RS14300	COG0586	Pfam SNARE associated Golgi protein
A7B19_RS14310	COG1358	cellular component organization or biogenesis
A7B19_RS14355	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
A7B19_RS14365	COG0477	Major facilitator Superfamily
A7B19_RS14370	COG1309	transcriptional regulator
A7B19_RS14385	COG4585	Histidine kinase
A7B19_RS14390	COG2197	response regulator
A7B19_RS14420	COG0789	Transcriptional regulator
A7B19_RS14440	COG4948	Mandelate Racemase Muconate Lactonizing
A7B19_RS14445	COG1063	alcohol dehydrogenase
A7B19_RS14450	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS14470	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A7B19_RS14475	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A7B19_RS14480	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A7B19_RS14505	COG1309	transcriptional regulator
A7B19_RS14555	COG1129	ABC transporter
A7B19_RS14560	COG4214	carbohydrate transport
A7B19_RS14585	COG0583	DNA-binding transcription factor activity
A7B19_RS14610	COG3866	Pectate lyase
A7B19_RS14620	COG1802	Transcriptional regulator
A7B19_RS14635	COG2084	Dehydrogenase
A7B19_RS14640	COG2610	gluconate transmembrane transporter activity
A7B19_RS14665	COG3507	Belongs to the glycosyl hydrolase 43 family
A7B19_RS14670	COG5520	Belongs to the glycosyl hydrolase 30 family
A7B19_RS14680	COG2130	NADP-dependent
A7B19_RS14700	COG3386	PFAM SMP-30 Gluconolaconase
A7B19_RS14705	COG1414	Transcriptional regulator
A7B19_RS14730	COG0500	methyltransferase
A7B19_RS14735	COG4981	capsule polysaccharide biosynthetic process
A7B19_RS14770	COG0588	phosphoglycerate mutase activity
A7B19_RS14775	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A7B19_RS14780	COG2318	DinB family
A7B19_RS14790	COG4221	oxidoreductase activity
A7B19_RS14840	COG1309	transcriptional regulator
A7B19_RS14865	COG4257	antibiotic catabolic process
A7B19_RS14875	COG0165	Argininosuccinate lyase
A7B19_RS14885	COG2318	DinB family
A7B19_RS14895	COG1846	Transcriptional regulator
A7B19_RS14905	COG2076	Multidrug Resistance protein
A7B19_RS14930	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A7B19_RS14960	COG1309	transcriptional regulator
A7B19_RS14975	COG1621	beta-fructofuranosidase activity
A7B19_RS14985	COG1175	transmembrane transport
A7B19_RS14990	COG0395	ABC-type sugar transport system, permease component
A7B19_RS14995	COG1621	beta-fructofuranosidase activity
A7B19_RS15000	COG1609	Transcriptional regulator
A7B19_RS15010	COG2197	response regulator
A7B19_RS15015	COG4585	Histidine kinase
A7B19_RS15065	COG2161	toxin-antitoxin pair type II binding
A7B19_RS15070	COG4115	mRNA cleavage
A7B19_RS15075	COG0583	DNA-binding transcription factor activity
A7B19_RS15080	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS15145	COG2318	DinB family
A7B19_RS15355	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
A7B19_RS15430	COG1715	Restriction endonuclease
A7B19_RS15475	COG1475	DNA binding
A7B19_RS15490	COG4974	Belongs to the 'phage' integrase family
A7B19_RS15515	COG1070	Carbohydrate kinase
A7B19_RS15525	COG0358	DNA primase activity
A7B19_RS15535	COG0232	Belongs to the dGTPase family. Type 2 subfamily
A7B19_RS15550	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
A7B19_RS15560	COG2949	membrane
A7B19_RS15665	COG2124	cytochrome p450
A7B19_RS15670	COG2124	cytochrome p450
A7B19_RS15675	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A7B19_RS15675	COG2146	nitrite reductase [NAD(P)H] activity
A7B19_RS15690	COG1609	Transcriptional regulator
A7B19_RS15700	COG1175	transmembrane transport
A7B19_RS15710	COG1472	Belongs to the glycosyl hydrolase 3 family
A7B19_RS15755	COG2271	Major facilitator Superfamily
A7B19_RS15760	COG1063	alcohol dehydrogenase
A7B19_RS15765	COG1414	Transcriptional regulator
A7B19_RS15770	COG1846	Transcriptional regulator
A7B19_RS15775	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
A7B19_RS15780	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
A7B19_RS15785	COG0183	Belongs to the thiolase family
A7B19_RS15790	COG3485	protocatechuate 3,4-dioxygenase
A7B19_RS15800	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A7B19_RS15805	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A7B19_RS15860	COG1309	transcriptional regulator
A7B19_RS15870	COG0574	Belongs to the PEP-utilizing enzyme family
A7B19_RS15870	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A7B19_RS15875	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
A7B19_RS15920	COG0667	Aldo Keto reductase
A7B19_RS15930	COG2197	response regulator
A7B19_RS15950	COG0423	glycine-tRNA ligase activity
A7B19_RS15960	COG1121	(ABC) transporter
A7B19_RS15965	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A7B19_RS15975	COG0346	lactoylglutathione lyase activity
A7B19_RS16015	COG3209	COG3209 Rhs family protein
A7B19_RS16040	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
A7B19_RS16045	COG1381	Involved in DNA repair and RecF pathway recombination
A7B19_RS16095	COG3422	double-strand break repair
A7B19_RS16120	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A7B19_RS16135	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
A7B19_RS16155	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
A7B19_RS16165	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A7B19_RS16170	COG1234	tRNA 3'-trailer cleavage
A7B19_RS16175	COG0537	adenosine 5'-monophosphoramidase activity
A7B19_RS16185	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A7B19_RS16205	COG0484	heat shock protein binding
A7B19_RS16210	COG1420	regulation of RNA biosynthetic process
A7B19_RS16235	COG1022	Amp-dependent synthetase and ligase
A7B19_RS16240	COG0481	GTPase activity
A7B19_RS16245	COG0268	Binds directly to 16S ribosomal RNA
A7B19_RS16265	COG4122	O-methyltransferase activity
A7B19_RS16275	COG1555	photosystem II stabilization
A7B19_RS16280	COG1307	EDD domain protein, DegV family
A7B19_RS16290	COG0495	leucyl-tRNA aminoacylation
A7B19_RS16310	COG0588	phosphoglycerate mutase activity
A7B19_RS16315	COG0799	negative regulation of ribosome biogenesis
A7B19_RS16325	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
A7B19_RS16330	COG0501	Belongs to the peptidase M48B family
A7B19_RS16345	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
A7B19_RS16355	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
A7B19_RS16365	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A7B19_RS16370	COG0211	Belongs to the bacterial ribosomal protein bL27 family
A7B19_RS16375	COG0261	This protein binds to 23S rRNA in the presence of protein L20
A7B19_RS16380	COG1530	ribonuclease E activity
A7B19_RS16400	COG0772	Belongs to the SEDS family
A7B19_RS16405	COG0768	penicillin binding
A7B19_RS16420	COG1077	Cell shape determining protein MreB Mrl
A7B19_RS16425	COG0105	UTP biosynthetic process
A7B19_RS16435	COG0285	dihydrofolate synthase activity
A7B19_RS16445	COG0525	valine-tRNA ligase activity
A7B19_RS16465	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
A7B19_RS16470	COG0740	serine-type endopeptidase activity
A7B19_RS16475	COG0740	serine-type endopeptidase activity
A7B19_RS16480	COG0544	peptidyl-prolyl cis-trans isomerase activity
A7B19_RS16500	COG3594	Acyltransferase
A7B19_RS16510	COG1136	(ABC) transporter
A7B19_RS16530	COG1113	amino acid transport
A7B19_RS16540	COG1113	amino acid transport
A7B19_RS16555	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A7B19_RS16565	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
A7B19_RS16590	COG0463	Glycosyl transferase, family 2
A7B19_RS16640	COG0668	transmembrane transport
A7B19_RS16650	COG1940	carbohydrate kinase activity
A7B19_RS16650	COG1846	Transcriptional regulator
A7B19_RS16660	COG1175	transmembrane transport
A7B19_RS16665	COG0395	ABC-type sugar transport system, permease component
A7B19_RS16670	COG1486	melibiose metabolic process
A7B19_RS16685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A7B19_RS16760	COG1846	Transcriptional regulator
A7B19_RS16770	COG1942	4-Oxalocrotonate Tautomerase
A7B19_RS16780	COG2814	Major facilitator Superfamily
A7B19_RS16785	COG2261	transglycosylase associated protein
A7B19_RS16815	COG3251	PFAM MbtH domain protein
A7B19_RS16820	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
A7B19_RS16825	COG1993	acr, cog1993
A7B19_RS16830	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
A7B19_RS16835	COG0583	DNA-binding transcription factor activity
A7B19_RS16850	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
A7B19_RS16870	COG0318	PFAM AMP-dependent synthetase and ligase
A7B19_RS16880	COG1131	(ABC) transporter
A7B19_RS16895	COG3321	synthase
A7B19_RS16895	COG0604	alcohol dehydrogenase
A7B19_RS16900	COG0604	alcohol dehydrogenase
A7B19_RS16900	COG3321	synthase
A7B19_RS16905	COG0604	alcohol dehydrogenase
A7B19_RS16905	COG3321	synthase
A7B19_RS16915	COG3321	synthase
A7B19_RS16915	COG0604	alcohol dehydrogenase
A7B19_RS16920	COG0604	alcohol dehydrogenase
A7B19_RS16920	COG3321	synthase
A7B19_RS16935	COG3321	synthase
A7B19_RS16935	COG0604	alcohol dehydrogenase
A7B19_RS16960	COG3402	PFAM membrane-flanked domain
A7B19_RS16970	COG4585	Histidine kinase
A7B19_RS16975	COG2197	response regulator
A7B19_RS17010	COG3718	enzyme involved in inositol metabolism
A7B19_RS17020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A7B19_RS17030	COG1172	Belongs to the binding-protein-dependent transport system permease family
A7B19_RS17045	COG0673	inositol 2-dehydrogenase activity
A7B19_RS17050	COG1082	Xylose isomerase domain protein TIM barrel
A7B19_RS17060	COG2409	Drug exporters of the RND superfamily
A7B19_RS17085	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A7B19_RS17095	COG1129	ABC transporter
A7B19_RS17105	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A7B19_RS17110	COG1869	D-ribose catabolic process
A7B19_RS17120	COG1316	TRANSCRIPTIONal
A7B19_RS17135	COG1595	DNA-templated transcription, initiation
A7B19_RS17175	COG0673	inositol 2-dehydrogenase activity
A7B19_RS17190	COG0395	ABC-type sugar transport system, permease component
A7B19_RS17195	COG1175	transmembrane transport
A7B19_RS17215	COG0673	inositol 2-dehydrogenase activity
A7B19_RS17220	COG1609	Transcriptional regulator
A7B19_RS17245	COG2207	Transcriptional regulator
A7B19_RS17270	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A7B19_RS17270	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A7B19_RS17295	COG2264	protein methyltransferase activity
A7B19_RS17305	COG0697	spore germination
A7B19_RS17310	COG0583	DNA-binding transcription factor activity
A7B19_RS17325	COG1472	Belongs to the glycosyl hydrolase 3 family
A7B19_RS17360	COG1554	hydrolase, family 65, central catalytic
A7B19_RS17400	COG1278	Cold shock
A7B19_RS17405	COG0513	Belongs to the DEAD box helicase family
A7B19_RS17415	COG1946	Acyl-CoA thioesterase
A7B19_RS17425	COG1309	transcriptional regulator
A7B19_RS17430	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A7B19_RS17445	COG1960	acyl-CoA dehydrogenase activity
A7B19_RS17470	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A7B19_RS17475	COG0589	response to stress
A7B19_RS17485	COG4977	sequence-specific DNA binding
A7B19_RS17490	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
A7B19_RS17510	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
A7B19_RS17520	COG0406	alpha-ribazole phosphatase activity
A7B19_RS17540	COG0477	Major facilitator Superfamily
A7B19_RS17565	COG1215	transferase activity, transferring glycosyl groups
A7B19_RS17570	COG5297	Belongs to the glycosyl hydrolase family 6
A7B19_RS17570	COG4733	cellulase activity
A7B19_RS17575	COG5297	Belongs to the glycosyl hydrolase family 6
A7B19_RS17580	COG5297	Belongs to the glycosyl hydrolase family 6
A7B19_RS17610	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
A7B19_RS17615	COG3979	chitinase
A7B19_RS17635	COG0406	alpha-ribazole phosphatase activity
A7B19_RS17680	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS17695	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
A7B19_RS17715	COG4585	Histidine kinase
A7B19_RS17720	COG2197	response regulator
A7B19_RS17740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A7B19_RS17775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A7B19_RS17780	COG0765	amino acid transport
A7B19_RS17785	COG0765	amino acid transport
A7B19_RS17790	COG1126	abc transporter atp-binding protein
A7B19_RS17850	COG1309	transcriptional regulator
A7B19_RS17870	COG4770	biotin carboxylase activity
A7B19_RS17885	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS17890	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
A7B19_RS17895	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
A7B19_RS17900	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A7B19_RS17905	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A7B19_RS17930	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
A7B19_RS17950	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A7B19_RS17955	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A7B19_RS17960	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A7B19_RS17965	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A7B19_RS17975	COG0477	Major facilitator Superfamily
A7B19_RS17995	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A7B19_RS18000	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A7B19_RS18035	COG3397	chitin binding
A7B19_RS18055	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A7B19_RS18090	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS18095	COG1309	transcriptional regulator
A7B19_RS18130	COG2186	Transcriptional regulator
A7B19_RS18210	COG0673	inositol 2-dehydrogenase activity
A7B19_RS18215	COG4702	Belongs to the UPF0303 family
A7B19_RS18240	COG0706	membrane insertase activity
A7B19_RS18245	COG3764	Sortase (surface protein transpeptidase)
A7B19_RS18250	COG2733	membrane
A7B19_RS18280	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A7B19_RS18285	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
A7B19_RS18315	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
A7B19_RS18325	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
A7B19_RS18330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A7B19_RS18335	COG1263	PTS System
A7B19_RS18340	COG1234	tRNA 3'-trailer cleavage
A7B19_RS18360	COG1113	amino acid transport
A7B19_RS18370	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
A7B19_RS18380	COG1335	isochorismatase
A7B19_RS18415	COG0277	FAD linked oxidase domain protein
A7B19_RS18425	COG1595	DNA-templated transcription, initiation
A7B19_RS18440	COG3185	4-Hydroxyphenylpyruvate dioxygenase
A7B19_RS18485	COG2855	membrane
A7B19_RS18495	COG0583	DNA-binding transcription factor activity
A7B19_RS18510	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A7B19_RS18520	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS18530	COG0456	acetyltransferase
A7B19_RS18550	COG3525	Glycosyl hydrolase, family 20, catalytic domain
A7B19_RS18555	COG0395	ABC-type sugar transport system, permease component
A7B19_RS18590	COG1678	Uncharacterized ACR, COG1678
A7B19_RS18595	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
A7B19_RS18600	COG0776	regulation of translation
A7B19_RS18610	COG1278	Cold shock
A7B19_RS18615	COG3973	AAA domain
A7B19_RS18640	COG2223	nitrite transmembrane transporter activity
A7B19_RS18670	COG0395	ABC-type sugar transport system, permease component
A7B19_RS18675	COG1501	Belongs to the glycosyl hydrolase 31 family
A7B19_RS18680	COG2027	D-alanyl-D-alanine carboxypeptidase
A7B19_RS18700	COG0604	alcohol dehydrogenase
A7B19_RS18730	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
A7B19_RS18735	COG0793	Belongs to the peptidase S41A family
A7B19_RS18740	COG2177	Part of the ABC transporter FtsEX involved in
A7B19_RS18745	COG2884	Cell division ATP-binding protein ftsE
A7B19_RS18760	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
A7B19_RS18765	COG0515	serine threonine protein kinase
A7B19_RS18785	COG1653	transport
A7B19_RS18790	COG1175	transmembrane transport
A7B19_RS18795	COG0395	ABC-type sugar transport system, permease component
A7B19_RS18800	COG0438	transferase activity, transferring glycosyl groups
A7B19_RS18870	COG0653	protein targeting
A7B19_RS18880	COG3214	Protein conserved in bacteria
A7B19_RS18885	COG2197	response regulator
A7B19_RS18890	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
A7B19_RS18900	COG0823	Involved in the tonB-independent uptake of proteins
A7B19_RS18905	COG5002	protein histidine kinase activity
A7B19_RS18910	COG0745	RESPONSE REGULATOR receiver
A7B19_RS18915	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
A7B19_RS18945	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
A7B19_RS18950	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A7B19_RS18950	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A7B19_RS18950	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A7B19_RS18960	COG1482	cell wall glycoprotein biosynthetic process
A7B19_RS18970	COG2835	tetraacyldisaccharide 4'-kinase activity
A7B19_RS18975	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A7B19_RS18985	COG1620	l-lactate permease
A7B19_RS19020	COG0391	Required for morphogenesis under gluconeogenic growth conditions
A7B19_RS19050	COG1316	TRANSCRIPTIONal
A7B19_RS19070	COG1316	TRANSCRIPTIONal
A7B19_RS19085	COG1607	acyl-coa hydrolase
A7B19_RS19090	COG1316	TRANSCRIPTIONal
A7B19_RS19105	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
A7B19_RS19125	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
A7B19_RS19140	COG2205	protein histidine kinase activity
A7B19_RS19145	COG0745	RESPONSE REGULATOR receiver
A7B19_RS19150	COG3104	oligopeptide transport
A7B19_RS19165	COG2027	D-alanyl-D-alanine carboxypeptidase
A7B19_RS19195	COG1366	Belongs to the anti-sigma-factor antagonist family
A7B19_RS19200	COG1191	sigma factor activity
A7B19_RS19205	COG1228	amidohydrolase
A7B19_RS19220	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
A7B19_RS19225	COG0604	alcohol dehydrogenase
A7B19_RS19250	COG2986	histidine ammonia-lyase
A7B19_RS19260	COG1174	glycine betaine transport
A7B19_RS19265	COG1174	glycine betaine transport
A7B19_RS19290	COG0318	PFAM AMP-dependent synthetase and ligase
A7B19_RS19305	COG2755	lipolytic protein G-D-S-L family
A7B19_RS19310	COG0183	Belongs to the thiolase family
A7B19_RS19340	COG0577	efflux transmembrane transporter activity
A7B19_RS19340	COG1136	(ABC) transporter
A7B19_RS19345	COG0577	efflux transmembrane transporter activity
A7B19_RS19350	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A7B19_RS19375	COG0148	phosphopyruvate hydratase activity
A7B19_RS19390	COG2124	cytochrome p450
A7B19_RS19420	COG2124	cytochrome p450
A7B19_RS19425	COG1024	Enoyl-CoA hydratase
A7B19_RS19475	COG2986	histidine ammonia-lyase
A7B19_RS19485	COG1024	Enoyl-CoA hydratase
A7B19_RS19490	COG2124	cytochrome p450
A7B19_RS19495	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
A7B19_RS19505	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A7B19_RS19520	COG0424	maF-like protein
A7B19_RS19530	COG4770	biotin carboxylase activity
A7B19_RS19570	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A7B19_RS19590	COG1012	belongs to the aldehyde dehydrogenase family
A7B19_RS19595	COG1012	belongs to the aldehyde dehydrogenase family
A7B19_RS19650	COG0745	RESPONSE REGULATOR receiver
A7B19_RS19655	COG2205	protein histidine kinase activity
A7B19_RS19680	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
A7B19_RS19700	COG0789	Transcriptional regulator
A7B19_RS19710	COG0477	Major facilitator Superfamily
A7B19_RS19715	COG1819	glycosyl
A7B19_RS19720	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
A7B19_RS19730	COG0583	DNA-binding transcription factor activity
A7B19_RS19735	COG2814	Major facilitator Superfamily
A7B19_RS19780	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
A7B19_RS19805	COG0488	(ABC) transporter
A7B19_RS19820	COG1079	Belongs to the binding-protein-dependent transport system permease family
A7B19_RS19825	COG4603	Belongs to the binding-protein-dependent transport system permease family
A7B19_RS19830	COG3845	ABC transporter
A7B19_RS19835	COG1744	ABC transporter substrate-binding protein PnrA-like
A7B19_RS19840	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
A7B19_RS19840	COG1473	amidohydrolase
A7B19_RS19850	COG2089	acid synthase
A7B19_RS19865	COG1216	Glycosyl transferase, family 2
A7B19_RS19960	COG1804	L-carnitine dehydratase bile acid-inducible protein F
A7B19_RS19995	COG1063	alcohol dehydrogenase
A7B19_RS20000	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS20010	COG3265	gluconokinase activity
A7B19_RS20015	COG2186	Transcriptional regulator
A7B19_RS20020	COG1064	alcohol dehydrogenase
A7B19_RS20025	COG1309	transcriptional regulator
A7B19_RS20035	COG0667	Aldo Keto reductase
A7B19_RS20045	COG0667	Aldo Keto reductase
A7B19_RS20120	COG0596	Alpha beta hydrolase
A7B19_RS20130	COG3903	Transcriptional regulator
A7B19_RS20130	COG3629	intracellular signal transduction
A7B19_RS20160	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A7B19_RS20165	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A7B19_RS20165	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A7B19_RS20180	COG1595	DNA-templated transcription, initiation
A7B19_RS20200	COG2009	succinate dehydrogenase
A7B19_RS20210	COG1053	succinate dehydrogenase
A7B19_RS20235	COG1408	metallophosphoesterase
A7B19_RS20245	COG1686	Belongs to the peptidase S11 family
A7B19_RS20250	COG1295	ribonuclease BN
A7B19_RS20260	COG0180	Tryptophanyl-tRNA synthetase
A7B19_RS20265	COG1595	DNA-templated transcription, initiation
A7B19_RS20270	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A7B19_RS20275	COG0754	glutathionylspermidine amidase activity
A7B19_RS20285	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A7B19_RS20290	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A7B19_RS20295	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
A7B19_RS20305	COG4176	ABC-type proline glycine betaine transport system permease component
A7B19_RS20310	COG0517	IMP dehydrogenase activity
A7B19_RS20310	COG4175	Glycine betaine
A7B19_RS20320	COG1012	belongs to the aldehyde dehydrogenase family
A7B19_RS20345	COG0039	L-malate dehydrogenase activity
A7B19_RS20360	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
A7B19_RS20365	COG0138	bifunctional purine biosynthesis protein purh
A7B19_RS20390	COG0045	succinate-CoA ligase (ADP-forming) activity
A7B19_RS20405	COG3552	Protein containing von Willebrand factor type A (VWA) domain
A7B19_RS20415	COG0714	Associated with various cellular activities
A7B19_RS20430	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A7B19_RS20440	COG0739	heme binding
A7B19_RS20475	COG0789	Transcriptional regulator
A7B19_RS20480	COG0789	Transcriptional regulator
A7B19_RS20500	COG1335	isochorismatase
A7B19_RS20530	COG1309	transcriptional regulator
A7B19_RS20550	COG2197	response regulator
A7B19_RS20600	COG0518	GMP synthase (glutamine-hydrolyzing) activity
A7B19_RS20600	COG0519	Catalyzes the synthesis of GMP from XMP
A7B19_RS20620	COG1012	belongs to the aldehyde dehydrogenase family
A7B19_RS20625	COG2815	serine threonine protein kinase
A7B19_RS20625	COG0515	serine threonine protein kinase
A7B19_RS20650	COG2197	response regulator
A7B19_RS20655	COG4585	Histidine kinase
A7B19_RS20705	COG1131	(ABC) transporter
A7B19_RS20725	COG2945	thiolester hydrolase activity
A7B19_RS20725	COG0596	Alpha beta hydrolase
A7B19_RS20735	COG4821	SIS domain
A7B19_RS20745	COG0259	pyridoxamine-phosphate oxidase activity
A7B19_RS20765	COG0318	PFAM AMP-dependent synthetase and ligase
A7B19_RS20780	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A7B19_RS20805	COG0247	lactate metabolic process
A7B19_RS20805	COG0277	FAD linked oxidase domain protein
A7B19_RS20810	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
A7B19_RS20825	COG0667	Aldo Keto reductase
A7B19_RS20875	COG2814	Major facilitator Superfamily
A7B19_RS20880	COG2814	Major facilitator Superfamily
A7B19_RS20890	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
A7B19_RS20895	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
A7B19_RS20900	COG1278	Cold shock
A7B19_RS20915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7B19_RS20920	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7B19_RS20925	COG1120	ATPase activity
A7B19_RS20950	COG3973	AAA domain
A7B19_RS21010	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
A7B19_RS21015	COG0459	protein refolding
A7B19_RS21020	COG1278	Cold shock
A7B19_RS21035	COG0463	Glycosyl transferase, family 2
A7B19_RS21040	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
A7B19_RS21045	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A7B19_RS21045	COG1877	trehalose-phosphatase activity
A7B19_RS21060	COG1940	carbohydrate kinase activity
A7B19_RS21065	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
A7B19_RS21090	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
A7B19_RS21140	COG2755	lipolytic protein G-D-S-L family
A7B19_RS21140	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
A7B19_RS21220	COG3842	ATPase activity
A7B19_RS21230	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
A7B19_RS21245	COG0215	cysteine-tRNA ligase activity
A7B19_RS21255	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
A7B19_RS21260	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
A7B19_RS21265	COG1329	Transcriptional regulator
A7B19_RS21280	COG5002	protein histidine kinase activity
A7B19_RS21305	COG1215	transferase activity, transferring glycosyl groups
A7B19_RS21330	COG0583	DNA-binding transcription factor activity
A7B19_RS21380	COG2188	Transcriptional regulator
A7B19_RS21445	COG0588	phosphoglycerate mutase activity
A7B19_RS21465	COG1116	anion transmembrane transporter activity
A7B19_RS21475	COG0438	transferase activity, transferring glycosyl groups
A7B19_RS21490	COG0531	amino acid
A7B19_RS21500	COG0667	Aldo Keto reductase
A7B19_RS21505	COG0494	nUDIX hydrolase
A7B19_RS21505	COG0406	alpha-ribazole phosphatase activity
A7B19_RS21515	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
A7B19_RS21520	COG0454	-acetyltransferase
A7B19_RS21520	COG0456	acetyltransferase
A7B19_RS21525	COG0737	Belongs to the 5'-nucleotidase family
A7B19_RS21550	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
A7B19_RS21570	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
A7B19_RS21580	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
A7B19_RS21585	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
A7B19_RS21605	COG0640	Transcriptional regulator
A7B19_RS21610	COG2197	response regulator
A7B19_RS21625	COG0649	NAD binding
A7B19_RS21640	COG1174	glycine betaine transport
A7B19_RS21650	COG0517	IMP dehydrogenase activity
A7B19_RS21650	COG1125	glycine betaine transport
A7B19_RS21660	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
A7B19_RS21660	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
A7B19_RS21675	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
A7B19_RS21680	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A7B19_RS21690	COG0302	gtp cyclohydrolase
A7B19_RS21715	COG2027	D-alanyl-D-alanine carboxypeptidase
A7B19_RS21720	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
A7B19_RS21730	COG0586	Pfam SNARE associated Golgi protein
A7B19_RS21735	COG0789	Transcriptional regulator
A7B19_RS21745	COG0076	glutamate decarboxylase activity
A7B19_RS21770	COG2318	DinB family
A7B19_RS21775	COG1012	belongs to the aldehyde dehydrogenase family
A7B19_RS21800	COG3940	Belongs to the glycosyl hydrolase 43 family
A7B19_RS21810	COG1077	Cell shape determining protein MreB Mrl
A7B19_RS21825	COG1595	DNA-templated transcription, initiation
A7B19_RS21830	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
A7B19_RS21835	COG0745	RESPONSE REGULATOR receiver
A7B19_RS21880	COG2197	response regulator
A7B19_RS21885	COG2197	response regulator
A7B19_RS21890	COG4585	Histidine kinase
A7B19_RS21895	COG0142	geranyltranstransferase activity
A7B19_RS21915	COG1191	sigma factor activity
A7B19_RS22155	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
A7B19_RS22160	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
A7B19_RS22165	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A7B19_RS22165	COG1754	DNA topoisomerase type I activity
A7B19_RS22175	COG2890	protein-(glutamine-N5) methyltransferase activity
A7B19_RS22185	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
A7B19_RS22190	COG2172	sigma factor antagonist activity
A7B19_RS22195	COG1366	Belongs to the anti-sigma-factor antagonist family
A7B19_RS22200	COG1205	dead DEAH box helicase
A7B19_RS22200	COG1111	helicase
A7B19_RS22255	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A7B19_RS22260	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
A7B19_RS22270	COG0596	Alpha beta hydrolase
A7B19_RS22300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A7B19_RS22320	COG0003	Pfam Anion-transporting ATPase
A7B19_RS22330	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A7B19_RS22340	COG1408	metallophosphoesterase
A7B19_RS22360	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
A7B19_RS22365	COG1846	Transcriptional regulator
A7B19_RS22410	COG2124	cytochrome p450
A7B19_RS22455	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
A7B19_RS22460	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
A7B19_RS22510	COG0697	spore germination
A7B19_RS22525	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
A7B19_RS22550	COG2814	Major facilitator Superfamily
A7B19_RS22560	COG0598	Magnesium transport protein CorA
A7B19_RS22565	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
A7B19_RS22580	COG2124	cytochrome p450
A7B19_RS22635	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
A7B19_RS22640	COG0436	Aminotransferase
A7B19_RS22645	COG4221	oxidoreductase activity
A7B19_RS22655	COG1984	allophanate hydrolase subunit 2
A7B19_RS22660	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
A7B19_RS22665	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
A7B19_RS22705	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A7B19_RS22720	COG3594	Acyltransferase
A7B19_RS22740	COG0702	epimerase
A7B19_RS22755	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
A7B19_RS22770	COG0590	tRNA wobble adenosine to inosine editing
A7B19_RS22800	COG1278	Cold shock
A7B19_RS22805	COG0513	Belongs to the DEAD box helicase family
A7B19_RS22830	COG3226	Transcriptional regulator
A7B19_RS22835	COG0789	Transcriptional regulator
A7B19_RS22860	COG3655	Transcriptional regulator
A7B19_RS22945	COG0205	6-phosphofructokinase activity
A7B19_RS22950	COG1191	sigma factor activity
A7B19_RS22955	COG1191	sigma factor activity
A7B19_RS22990	COG0477	Major facilitator Superfamily
A7B19_RS22995	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
A7B19_RS23005	COG2205	protein histidine kinase activity
A7B19_RS23010	COG0745	RESPONSE REGULATOR receiver
A7B19_RS23065	COG0318	PFAM AMP-dependent synthetase and ligase
A7B19_RS23070	COG1595	DNA-templated transcription, initiation
A7B19_RS23090	COG1960	acyl-CoA dehydrogenase activity
A7B19_RS23100	COG1960	acyl-CoA dehydrogenase activity
A7B19_RS23130	COG0477	Major facilitator Superfamily
A7B19_RS23170	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A7B19_RS23185	COG0653	protein targeting
A7B19_RS23200	COG0006	proline dipeptidase activity
A7B19_RS23205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A7B19_RS23230	COG1999	signal sequence binding
A7B19_RS23245	COG2837	iron assimilation
A7B19_RS23250	COG0077	Prephenate dehydratase
A7B19_RS23255	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
A7B19_RS23260	COG0561	phosphatase activity
A7B19_RS23300	COG1131	(ABC) transporter
A7B19_RS23315	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
A7B19_RS23325	COG0501	Belongs to the peptidase M48B family
A7B19_RS23335	COG0561	phosphatase activity
A7B19_RS23350	COG4988	ABC transporter
A7B19_RS23355	COG1294	oxidase, subunit
A7B19_RS23360	COG1271	oxidase subunit
A7B19_RS23370	COG1609	Transcriptional regulator
A7B19_RS23405	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
A7B19_RS23425	COG0662	Cupin 2, conserved barrel domain protein
A7B19_RS23430	COG1950	PFAM Membrane protein of
A7B19_RS23435	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A7B19_RS23440	COG0626	cystathionine gamma-synthase activity
A7B19_RS23500	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A7B19_RS23510	COG0242	peptide deformylase activity
A7B19_RS23515	COG0305	Participates in initiation and elongation during chromosome replication
A7B19_RS23520	COG0534	Mate efflux family protein
A7B19_RS23525	COG0359	binds to the 23S rRNA
A7B19_RS23530	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
A7B19_RS23535	COG0629	single-stranded DNA binding
A7B19_RS23540	COG0360	Binds together with S18 to 16S ribosomal RNA
A7B19_RS23565	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A7B19_RS23585	COG0617	tRNA 3'-terminal CCA addition
A7B19_RS23605	COG1595	DNA-templated transcription, initiation
A7B19_RS23615	COG0492	ferredoxin-NADP+ reductase activity
A7B19_RS23620	COG3118	belongs to the thioredoxin family
A7B19_RS23635	COG1192	Involved in chromosome partitioning
A7B19_RS23640	COG0357	Ribosomal RNA small subunit methyltransferase G
A7B19_RS23650	COG0706	membrane insertase activity
A7B19_RS23655	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
A7B19_RS23660	COG0230	Belongs to the bacterial ribosomal protein bL34 family
A7B19_RS23670	COG0592	DNA-directed DNA polymerase activity
A7B19_RS23675	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
A7B19_RS23680	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
A7B19_RS23685	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
A7B19_RS23690	COG0187	DNA topoisomerase II activity
A7B19_RS23695	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A7B19_RS23715	COG0515	serine threonine protein kinase
A7B19_RS23745	COG0705	Rhomboid family
A7B19_RS23760	COG3764	Sortase (surface protein transpeptidase)
A7B19_RS23770	COG3764	Sortase (surface protein transpeptidase)
A7B19_RS23775	COG3764	Sortase (surface protein transpeptidase)
A7B19_RS23780	COG0515	serine threonine protein kinase
A7B19_RS23785	COG0768	penicillin binding
A7B19_RS23800	COG1716	ATPase activity
A7B19_RS23815	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
A7B19_RS23820	COG1733	regulation of RNA biosynthetic process
A7B19_RS23845	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A7B19_RS23850	COG2151	metal-sulfur cluster biosynthetic enzyme
A7B19_RS23855	COG3396	Phenylacetate-CoA oxygenase
A7B19_RS23860	COG3460	Phenylacetate-CoA oxygenase
A7B19_RS23865	COG3396	Phenylacetate-CoA oxygenase
A7B19_RS23880	COG1595	DNA-templated transcription, initiation
A7B19_RS23885	COG0446	pyridine nucleotide-disulphide oxidoreductase
A7B19_RS23885	COG1902	pentaerythritol trinitrate reductase activity
A7B19_RS23900	COG1250	3-hydroxyacyl-CoA dehydrogenase
A7B19_RS23905	COG1309	transcriptional regulator
A7B19_RS23910	COG1522	sequence-specific DNA binding
A7B19_RS23940	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A7B19_RS23960	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A7B19_RS23965	COG0515	serine threonine protein kinase
A7B19_RS23970	COG0515	serine threonine protein kinase
A7B19_RS23990	COG0022	dehydrogenase e1 component
A7B19_RS23995	COG0508	dehydrogenase complex catalyzes the overall conversion of
A7B19_RS24040	COG1362	aminopeptidase activity
A7B19_RS24055	COG1960	acyl-CoA dehydrogenase activity
A7B19_RS24075	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
A7B19_RS24095	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A7B19_RS24125	COG1793	dna ligase
A7B19_RS24135	COG3290	protein histidine kinase activity
A7B19_RS24220	COG0243	molybdopterin cofactor binding
A7B19_RS24230	COG0725	ABC transporter, periplasmic molybdate-binding protein
A7B19_RS24240	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
A7B19_RS24255	COG0604	alcohol dehydrogenase
A7B19_RS24260	COG0384	phenazine biosynthesis protein PhzF
A7B19_RS24265	COG0583	DNA-binding transcription factor activity
A7B19_RS24315	COG0267	Belongs to the bacterial ribosomal protein bL33 family
A7B19_RS24320	COG0254	rRNA binding
A7B19_RS24330	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
A7B19_RS24335	COG0515	serine threonine protein kinase
A7B19_RS24335	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A7B19_RS24400	COG2402	Toxic component of a toxin-antitoxin (TA) module. An RNase
A7B19_RS24405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A7B19_RS24410	COG0076	glutamate decarboxylase activity
A7B19_RS24460	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
A7B19_RS24470	COG1280	lysine exporter protein (LysE YggA)
A7B19_RS24485	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS24500	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
A7B19_RS24525	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A7B19_RS24555	COG0717	Belongs to the dCTP deaminase family
A7B19_RS24560	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
A7B19_RS24575	COG3290	protein histidine kinase activity
A7B19_RS24580	COG0247	lactate metabolic process
A7B19_RS24580	COG2181	nitrate reductase activity
A7B19_RS24585	COG0443	Heat shock 70 kDa protein
A7B19_RS24590	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
A7B19_RS24595	COG0484	heat shock protein binding
A7B19_RS24600	COG0789	Transcriptional regulator
A7B19_RS24645	COG0542	response to heat
A7B19_RS24675	COG2017	converts alpha-aldose to the beta-anomer
A7B19_RS24680	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
A7B19_RS24685	COG0191	fructose-bisphosphate aldolase activity
A7B19_RS24690	COG0477	Major facilitator Superfamily
A7B19_RS24700	COG3483	tryptophan 2,3-dioxygenase activity
A7B19_RS24705	COG3844	kynureninase activity
A7B19_RS24720	COG2197	response regulator
A7B19_RS24725	COG2124	cytochrome p450
A7B19_RS24730	COG3559	Exporter of polyketide antibiotics
A7B19_RS24735	COG1131	(ABC) transporter
A7B19_RS24750	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
A7B19_RS24755	COG0515	serine threonine protein kinase
A7B19_RS24755	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A7B19_RS24780	COG0745	RESPONSE REGULATOR receiver
A7B19_RS24795	COG1802	Transcriptional regulator
A7B19_RS24810	COG0151	Belongs to the GarS family
A7B19_RS24825	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
A7B19_RS24835	COG2197	response regulator
A7B19_RS24850	COG1131	(ABC) transporter
A7B19_RS24870	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A7B19_RS24875	COG0047	phosphoribosylformylglycinamidine synthase activity
A7B19_RS24880	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A7B19_RS24895	COG3119	arylsulfatase activity
A7B19_RS24905	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
A7B19_RS24915	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A7B19_RS24940	COG1643	Atp-dependent helicase
A7B19_RS24965	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A7B19_RS24975	COG0109	protoheme IX farnesyltransferase activity
A7B19_RS24990	COG2175	clavaminate synthase activity
A7B19_RS25000	COG0667	Aldo Keto reductase
A7B19_RS25020	COG0477	Major facilitator Superfamily
A7B19_RS25030	COG3739	integral membrane protein
A7B19_RS25055	COG0546	phosphoglycolate phosphatase activity
A7B19_RS25080	COG1396	sequence-specific DNA binding
A7B19_RS25100	COG4948	Mandelate Racemase Muconate Lactonizing
A7B19_RS25140	COG0513	Belongs to the DEAD box helicase family
A7B19_RS25185	COG1196	nuclear chromosome segregation
A7B19_RS25185	COG0741	lytic transglycosylase activity
A7B19_RS25185	COG0739	heme binding
A7B19_RS25190	COG0667	Aldo Keto reductase
A7B19_RS25235	COG0220	tRNA (guanine-N7-)-methyltransferase activity
A7B19_RS25240	COG0579	oxidoreductase
A7B19_RS25265	COG1252	NADH dehydrogenase
A7B19_RS25280	COG1846	Transcriptional regulator
A7B19_RS25310	COG0193	aminoacyl-tRNA hydrolase activity
A7B19_RS25335	COG0739	heme binding
A7B19_RS25335	COG1196	nuclear chromosome segregation
A7B19_RS25335	COG0741	lytic transglycosylase activity
A7B19_RS25340	COG0671	phosphoesterase, PA-phosphatase related
A7B19_RS25360	COG1937	Protein conserved in bacteria
A7B19_RS25375	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A7B19_RS25390	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
A7B19_RS25420	COG2249	NAD(P)H dehydrogenase (quinone) activity
A7B19_RS25475	COG1490	D-aminoacyl-tRNA deacylase activity
A7B19_RS25485	COG0735	belongs to the Fur family
A7B19_RS25490	COG3485	protocatechuate 3,4-dioxygenase
A7B19_RS25510	COG2897	thiosulfate sulfurtransferase activity
A7B19_RS25545	COG0745	RESPONSE REGULATOR receiver
A7B19_RS25550	COG1609	Transcriptional regulator
A7B19_RS25555	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A7B19_RS25560	COG0745	RESPONSE REGULATOR receiver
A7B19_RS25595	COG1131	(ABC) transporter
A7B19_RS25600	COG1132	(ABC) transporter
A7B19_RS25610	COG0724	RNA recognition motif
A7B19_RS25620	COG0789	Transcriptional regulator
A7B19_RS25650	COG0745	RESPONSE REGULATOR receiver
A7B19_RS25700	COG0739	heme binding
A7B19_RS25720	COG0346	lactoylglutathione lyase activity
A7B19_RS25730	COG0745	RESPONSE REGULATOR receiver
A7B19_RS25740	COG1595	DNA-templated transcription, initiation
A7B19_RS25745	COG1194	a g-specific adenine glycosylase
A7B19_RS25755	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
A7B19_RS25775	COG0248	Ppx GppA phosphatase
A7B19_RS25780	COG1082	Xylose isomerase domain protein TIM barrel
A7B19_RS25785	COG1309	transcriptional regulator
A7B19_RS25795	COG0515	serine threonine protein kinase
A7B19_RS25795	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A7B19_RS25815	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A7B19_RS25820	COG0180	Tryptophanyl-tRNA synthetase
A7B19_RS25840	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A7B19_RS25850	COG0123	including yeast histone deacetylase and acetoin utilization protein
A7B19_RS25895	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
A7B19_RS25900	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
A7B19_RS25905	COG0181	hydroxymethylbilane synthase activity
A7B19_RS25910	COG1648	precorrin-2 dehydrogenase activity
A7B19_RS25910	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
A7B19_RS25915	COG0113	porphobilinogen synthase activity
A7B19_RS25940	COG1434	Gram-negative-bacterium-type cell wall biogenesis
A7B19_RS25955	COG1072	(Pantothenic acid kinase))
A7B19_RS25985	COG0018	arginyl-trna synthetase
A7B19_RS25990	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
A7B19_RS26010	COG1690	Belongs to the RtcB family
A7B19_RS26025	COG1742	UPF0060 membrane protein
A7B19_RS26035	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
A7B19_RS26040	COG0406	alpha-ribazole phosphatase activity
A7B19_RS26060	COG1333	cytochrome c biogenesis protein
A7B19_RS26065	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A7B19_RS26075	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
A7B19_RS26080	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
A7B19_RS26085	COG0163	prenyltransferase activity
A7B19_RS26100	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
A7B19_RS26105	COG1573	uracil-dna glycosylase
A7B19_RS26140	COG1222	aaa ATPase
A7B19_RS26150	COG1309	transcriptional regulator
A7B19_RS26175	COG1278	Cold shock
A7B19_RS26180	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
A7B19_RS26190	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
A7B19_RS26200	COG2226	methyltransferase
A7B19_RS26225	COG0791	NLP P60 protein
A7B19_RS26225	COG1388	LysM domain
A7B19_RS26225	COG3103	Sh3 type 3 domain protein
A7B19_RS26235	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A7B19_RS26240	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A7B19_RS26245	COG0649	NAD binding
A7B19_RS26255	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
A7B19_RS26260	COG1034	ATP synthesis coupled electron transport
A7B19_RS26265	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
A7B19_RS26270	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A7B19_RS26275	COG0839	Belongs to the complex I subunit 6 family
A7B19_RS26280	COG0713	ATP synthesis coupled electron transport
A7B19_RS26285	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A7B19_RS26295	COG1007	ATP synthesis coupled electron transport
A7B19_RS26300	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
A7B19_RS26305	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
A7B19_RS26325	COG2188	Transcriptional regulator
A7B19_RS26345	COG0492	ferredoxin-NADP+ reductase activity
A7B19_RS26350	COG0142	geranyltranstransferase activity
A7B19_RS26380	COG0702	epimerase
A7B19_RS26385	COG1733	regulation of RNA biosynthetic process
A7B19_RS26390	COG1013	pyruvate-flavodoxin oxidoreductase activity
A7B19_RS26395	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
A7B19_RS26395	COG0674	pyruvate-flavodoxin oxidoreductase activity
A7B19_RS26400	COG2197	response regulator
A7B19_RS26405	COG4585	Histidine kinase
A7B19_RS26410	COG4585	Histidine kinase
A7B19_RS26415	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A7B19_RS26420	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A7B19_RS26425	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A7B19_RS26435	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A7B19_RS26440	COG0839	Belongs to the complex I subunit 6 family
A7B19_RS26445	COG0713	ATP synthesis coupled electron transport
A7B19_RS26450	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A7B19_RS26460	COG1007	ATP synthesis coupled electron transport
A7B19_RS26465	COG0501	Belongs to the peptidase M48B family
A7B19_RS26470	COG3304	Inner membrane component domain
A7B19_RS26485	COG1666	GTP binding
A7B19_RS26495	COG2188	Transcriptional regulator
A7B19_RS26510	COG2319	Wd-40 repeat
A7B19_RS26510	COG4249	Peptidase C14 caspase catalytic subunit p20
A7B19_RS26525	COG0702	epimerase
A7B19_RS26530	COG0402	S-adenosylhomocysteine deaminase activity
A7B19_RS26545	COG0267	Belongs to the bacterial ribosomal protein bL33 family
A7B19_RS26550	COG2030	dehydratase
A7B19_RS26560	COG0812	UDP-N-acetylmuramate dehydrogenase activity
A7B19_RS26565	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
A7B19_RS26570	COG0436	Aminotransferase
A7B19_RS26590	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
A7B19_RS26595	COG0081	regulation of translation
A7B19_RS26605	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
A7B19_RS26610	COG0222	ribosome binding
A7B19_RS26615	COG0085	RNA polymerase activity
A7B19_RS26620	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
A7B19_RS26625	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
A7B19_RS26630	COG0049	tRNA binding
A7B19_RS26635	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
A7B19_RS26640	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
A7B19_RS26670	COG1595	DNA-templated transcription, initiation
A7B19_RS26680	COG0051	transcription antitermination factor activity, RNA binding
A7B19_RS26685	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
A7B19_RS26690	COG0088	Forms part of the polypeptide exit tunnel
A7B19_RS26695	COG0089	rRNA binding
A7B19_RS26700	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
A7B19_RS26705	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
A7B19_RS26710	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
A7B19_RS26715	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
A7B19_RS26720	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
A7B19_RS26725	COG0255	Belongs to the universal ribosomal protein uL29 family
A7B19_RS26730	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
A7B19_RS26735	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
A7B19_RS26740	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
A7B19_RS26745	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
A7B19_RS26750	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
A7B19_RS26755	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
A7B19_RS26760	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
A7B19_RS26765	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
A7B19_RS26770	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
A7B19_RS26780	COG0200	Binds to the 23S rRNA
A7B19_RS26790	COG0563	adenylate kinase activity
A7B19_RS26800	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
A7B19_RS26805	COG0257	Belongs to the bacterial ribosomal protein bL36 family
A7B19_RS26810	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
A7B19_RS26815	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
A7B19_RS26820	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
A7B19_RS26825	COG0202	RNA polymerase activity
A7B19_RS26830	COG0203	ribosomal protein L17
A7B19_RS26835	COG0101	tRNA pseudouridine synthase activity
A7B19_RS26840	COG1366	Belongs to the anti-sigma-factor antagonist family
A7B19_RS26845	COG1366	Belongs to the anti-sigma-factor antagonist family
A7B19_RS26850	COG2172	sigma factor antagonist activity
A7B19_RS26860	COG2770	Histidine kinase
A7B19_RS26860	COG2208	phosphoserine phosphatase activity
A7B19_RS26870	COG0438	transferase activity, transferring glycosyl groups
A7B19_RS26925	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
A7B19_RS26930	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
A7B19_RS26935	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A7B19_RS26945	COG1072	(Pantothenic acid kinase))
A7B19_RS26950	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A7B19_RS26955	COG0736	holo-[acyl-carrier-protein] synthase activity
A7B19_RS26980	COG0535	radical SAM domain protein
A7B19_RS27020	COG0667	Aldo Keto reductase
A7B19_RS27035	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A7B19_RS27045	COG0802	atpase or kinase
A7B19_RS27070	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
A7B19_RS27120	COG0726	polysaccharide deacetylase
A7B19_RS27125	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
A7B19_RS27130	COG0459	protein refolding
A7B19_RS27140	COG0583	DNA-binding transcription factor activity
A7B19_RS27150	COG2197	response regulator
A7B19_RS27155	COG1595	DNA-templated transcription, initiation
A7B19_RS27165	COG0516	GMP reductase activity
A7B19_RS27175	COG1077	Cell shape determining protein MreB Mrl
A7B19_RS27190	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
A7B19_RS27210	COG0318	PFAM AMP-dependent synthetase and ligase
A7B19_RS27215	COG1960	acyl-CoA dehydrogenase activity
A7B19_RS27220	COG1960	acyl-CoA dehydrogenase activity
A7B19_RS27235	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS27240	COG1960	acyl-CoA dehydrogenase activity
A7B19_RS27270	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A7B19_RS27275	COG1024	Enoyl-CoA hydratase
A7B19_RS27285	COG2072	flavoprotein involved in K transport
A7B19_RS27295	COG5002	protein histidine kinase activity
A7B19_RS27300	COG2018	Roadblock/LC7 domain
A7B19_RS27325	COG0259	pyridoxamine-phosphate oxidase activity
A7B19_RS27335	COG1960	acyl-CoA dehydrogenase activity
A7B19_RS27345	COG1309	transcriptional regulator
A7B19_RS27355	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A7B19_RS27355	COG0515	serine threonine protein kinase
A7B19_RS27370	COG1024	Enoyl-CoA hydratase
A7B19_RS27425	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A7B19_RS27445	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS27505	COG1301	dicarboxylic acid transport
A7B19_RS27515	COG1802	Transcriptional regulator
A7B19_RS27530	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
A7B19_RS27540	COG0640	Transcriptional regulator
A7B19_RS27560	COG1278	Cold shock
A7B19_RS27565	COG0513	Belongs to the DEAD box helicase family
A7B19_RS27615	COG1686	Belongs to the peptidase S11 family
A7B19_RS27625	COG1653	transport
A7B19_RS27640	COG0515	serine threonine protein kinase
A7B19_RS27680	COG0702	epimerase
A7B19_RS27685	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
A7B19_RS27690	COG3285	dna ligase
A7B19_RS27690	COG1793	dna ligase
A7B19_RS27705	COG2515	1-aminocyclopropane-1-carboxylate deaminase
A7B19_RS27725	COG0824	Thioesterase
A7B19_RS27725	COG1250	3-hydroxyacyl-CoA dehydrogenase
A7B19_RS27730	COG1250	3-hydroxyacyl-CoA dehydrogenase
A7B19_RS27735	COG3246	L-lysine catabolic process to acetate
A7B19_RS27755	COG0515	serine threonine protein kinase
A7B19_RS27765	COG2197	response regulator
A7B19_RS27775	COG0464	growth
A7B19_RS27900	COG3903	Transcriptional regulator
A7B19_RS27900	COG3629	intracellular signal transduction
A7B19_RS27940	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
A7B19_RS27975	COG1309	transcriptional regulator
A7B19_RS27995	COG1929	Belongs to the glycerate kinase type-1 family
A7B19_RS28000	COG0583	DNA-binding transcription factor activity
A7B19_RS28040	COG0789	Transcriptional regulator
A7B19_RS28060	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A7B19_RS28070	COG4585	Histidine kinase
A7B19_RS28075	COG2197	response regulator
A7B19_RS28135	COG0019	diaminopimelate decarboxylase activity
A7B19_RS28140	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
A7B19_RS28145	COG0765	amino acid transport
A7B19_RS28150	COG1126	abc transporter atp-binding protein
A7B19_RS28155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A7B19_RS28200	COG0076	glutamate decarboxylase activity
A7B19_RS28230	COG1309	transcriptional regulator
A7B19_RS28250	COG1846	Transcriptional regulator
A7B19_RS28255	COG3384	dioxygenase
A7B19_RS28270	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS28280	COG1105	Belongs to the carbohydrate kinase PfkB family
A7B19_RS28290	COG3634	alkyl hydroperoxide reductase activity
A7B19_RS28300	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A7B19_RS28310	COG1970	mechanosensitive ion channel activity
A7B19_RS28320	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
A7B19_RS28330	COG3263	regulation of cellular component size
A7B19_RS28340	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
A7B19_RS28345	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A7B19_RS28355	COG0315	cyclic pyranopterin monophosphate synthase activity
A7B19_RS28360	COG0315	cyclic pyranopterin monophosphate synthase activity
A7B19_RS28360	COG0521	Mo-molybdopterin cofactor biosynthetic process
A7B19_RS28365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A7B19_RS28380	COG0582	viral genome integration into host DNA
A7B19_RS28415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A7B19_RS28435	COG1280	lysine exporter protein (LysE YggA)
A7B19_RS28455	COG0708	Exodeoxyribonuclease III
A7B19_RS28460	COG0789	Transcriptional regulator
A7B19_RS28465	COG2072	flavoprotein involved in K transport
A7B19_RS28475	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS28495	COG2409	Drug exporters of the RND superfamily
A7B19_RS28500	COG0310	cobalt ion transport
A7B19_RS28510	COG1122	ATPase activity
A7B19_RS28540	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A7B19_RS28545	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS28560	COG1917	Cupin 2, conserved barrel domain protein
A7B19_RS28590	COG0084	hydrolase, TatD family'
A7B19_RS28600	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
A7B19_RS28605	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
A7B19_RS28610	COG0488	(ABC) transporter
A7B19_RS28645	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
A7B19_RS28650	COG2197	response regulator
A7B19_RS28660	COG4106	trans-aconitate 2-methyltransferase activity
A7B19_RS28665	COG1309	transcriptional regulator
A7B19_RS28675	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
A7B19_RS28685	COG0193	aminoacyl-tRNA hydrolase activity
A7B19_RS28690	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
A7B19_RS28695	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
A7B19_RS28700	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
A7B19_RS28710	COG4585	Histidine kinase
A7B19_RS28740	COG2814	Major facilitator Superfamily
A7B19_RS28745	COG1136	(ABC) transporter
A7B19_RS28750	COG0577	efflux transmembrane transporter activity
A7B19_RS28760	COG0667	Aldo Keto reductase
A7B19_RS28775	COG0346	lactoylglutathione lyase activity
A7B19_RS28895	COG1396	sequence-specific DNA binding
A7B19_RS28900	COG0740	serine-type endopeptidase activity
A7B19_RS28905	COG0740	serine-type endopeptidase activity
A7B19_RS28930	COG5002	protein histidine kinase activity
A7B19_RS28935	COG2018	Roadblock/LC7 domain
A7B19_RS28955	COG0640	Transcriptional regulator
A7B19_RS28960	COG1234	tRNA 3'-trailer cleavage
A7B19_RS28990	COG0667	Aldo Keto reductase
A7B19_RS29030	COG1819	glycosyl
A7B19_RS29040	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A7B19_RS29060	COG1595	DNA-templated transcription, initiation
A7B19_RS29070	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
A7B19_RS29085	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A7B19_RS29095	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A7B19_RS29110	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS29120	COG2814	Major facilitator Superfamily
A7B19_RS29130	COG0154	amidase activity
A7B19_RS29135	COG1331	Highly conserved protein containing a thioredoxin domain
A7B19_RS29145	COG1272	protein, Hemolysin III
A7B19_RS29150	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
A7B19_RS29160	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
A7B19_RS29180	COG0601	transmembrane transport
A7B19_RS29185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A7B19_RS29245	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
A7B19_RS29260	COG1414	Transcriptional regulator
A7B19_RS29270	COG2610	gluconate transmembrane transporter activity
A7B19_RS29310	COG2894	cell division
A7B19_RS29350	COG2885	chlorophyll binding
A7B19_RS29355	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A7B19_RS29365	COG1278	Cold shock
A7B19_RS29380	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
A7B19_RS29385	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
A7B19_RS29400	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A7B19_RS29405	COG0450	alkyl hydroperoxide reductase
A7B19_RS29450	COG0450	alkyl hydroperoxide reductase
A7B19_RS29465	COG1136	(ABC) transporter
A7B19_RS29485	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A7B19_RS29495	COG2226	methyltransferase
A7B19_RS29510	COG0114	fumarate hydratase activity
A7B19_RS29520	COG3979	chitinase
A7B19_RS29525	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
A7B19_RS29525	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
A7B19_RS29550	COG0778	Nitroreductase
A7B19_RS29555	COG1722	exodeoxyribonuclease VII activity
A7B19_RS29560	COG1570	exodeoxyribonuclease VII activity
A7B19_RS29565	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
A7B19_RS29580	COG0012	GTP binding
A7B19_RS29585	COG0477	Major facilitator Superfamily
A7B19_RS29595	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
A7B19_RS29630	COG0531	amino acid
A7B19_RS29660	COG1053	succinate dehydrogenase
A7B19_RS29680	COG1217	gtp-binding protein TYPA
A7B19_RS29685	COG4166	transmembrane transport
A7B19_RS29690	COG0601	transmembrane transport
A7B19_RS29695	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A7B19_RS29705	COG4608	Belongs to the ABC transporter superfamily
A7B19_RS29740	COG4166	transmembrane transport
A7B19_RS29745	COG0601	transmembrane transport
A7B19_RS29750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A7B19_RS29760	COG4608	Belongs to the ABC transporter superfamily
A7B19_RS29780	COG4977	sequence-specific DNA binding
A7B19_RS29785	COG0702	epimerase
A7B19_RS29795	COG4608	Belongs to the ABC transporter superfamily
A7B19_RS29800	COG0444	Belongs to the ABC transporter superfamily
A7B19_RS29815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A7B19_RS29835	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A7B19_RS29850	COG1131	(ABC) transporter
A7B19_RS29860	COG4585	Histidine kinase
A7B19_RS29865	COG2197	response regulator
A7B19_RS29900	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A7B19_RS29905	COG1611	Belongs to the LOG family
A7B19_RS29910	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
A7B19_RS29920	COG0519	Catalyzes the synthesis of GMP from XMP
A7B19_RS29925	COG1024	Enoyl-CoA hydratase
A7B19_RS29935	COG1595	DNA-templated transcription, initiation
A7B19_RS29945	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A7B19_RS29950	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A7B19_RS29990	COG0598	Magnesium transport protein CorA
A7B19_RS30005	COG0613	PHP domain protein
A7B19_RS30010	COG1432	Conserved Protein
A7B19_RS30015	COG0596	Alpha beta hydrolase
A7B19_RS30020	COG0513	Belongs to the DEAD box helicase family
A7B19_RS30110	COG0210	DNA helicase
A7B19_RS30115	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A7B19_RS30140	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
A7B19_RS30190	COG3480	Lon protease (S16) C-terminal proteolytic domain
A7B19_RS30200	COG1615	UPF0182 protein
A7B19_RS30225	COG0753	catalase activity
A7B19_RS30235	COG0483	inositol monophosphate 1-phosphatase activity
A7B19_RS30245	COG2076	Multidrug Resistance protein
A7B19_RS30255	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
A7B19_RS30265	COG2135	peptidase activity
A7B19_RS30275	COG1595	DNA-templated transcription, initiation
A7B19_RS30280	COG5662	AntiSigma factor
A7B19_RS30285	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
A7B19_RS30285	COG2199	diguanylate cyclase activity
A7B19_RS30300	COG0242	peptide deformylase activity
A7B19_RS30320	COG0588	phosphoglycerate mutase activity
A7B19_RS30325	COG1349	DNA-binding transcription factor activity
A7B19_RS30370	COG2188	Transcriptional regulator
A7B19_RS30375	COG1472	Belongs to the glycosyl hydrolase 3 family
A7B19_RS30380	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A7B19_RS30395	COG1597	lipid kinase activity
A7B19_RS30435	COG2066	Belongs to the glutaminase family
A7B19_RS30455	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A7B19_RS30480	COG5640	endopeptidase activity
A7B19_RS30485	COG0583	DNA-binding transcription factor activity
A7B19_RS30525	COG1126	abc transporter atp-binding protein
A7B19_RS30530	COG0765	amino acid transport
A7B19_RS30535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A7B19_RS30540	COG0281	malic enzyme
A7B19_RS30545	COG0604	alcohol dehydrogenase
A7B19_RS30570	COG3321	synthase
A7B19_RS30570	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS30570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A7B19_RS30570	COG0300	oxidoreductase activity
A7B19_RS30570	COG0318	PFAM AMP-dependent synthetase and ligase
A7B19_RS30585	COG0778	Nitroreductase
A7B19_RS30605	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS30625	COG0508	dehydrogenase complex catalyzes the overall conversion of
A7B19_RS30625	COG0567	Dehydrogenase, E1 component
A7B19_RS30630	COG2205	protein histidine kinase activity
A7B19_RS30635	COG0745	RESPONSE REGULATOR receiver
A7B19_RS30660	COG1131	(ABC) transporter
A7B19_RS30670	COG1595	DNA-templated transcription, initiation
A7B19_RS30675	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
A7B19_RS30680	COG2249	NAD(P)H dehydrogenase (quinone) activity
A7B19_RS30685	COG1309	transcriptional regulator
A7B19_RS30730	COG3103	Sh3 type 3 domain protein
A7B19_RS30730	COG1388	LysM domain
A7B19_RS30730	COG0791	NLP P60 protein
A7B19_RS30775	COG2814	Major facilitator Superfamily
A7B19_RS30785	COG0477	Major facilitator Superfamily
A7B19_RS30875	COG1201	RNA secondary structure unwinding
A7B19_RS30930	COG0745	RESPONSE REGULATOR receiver
A7B19_RS30940	COG0019	diaminopimelate decarboxylase activity
A7B19_RS30945	COG0460	homoserine dehydrogenase
A7B19_RS30950	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
A7B19_RS30955	COG0083	homoserine kinase activity
A7B19_RS30965	COG1316	TRANSCRIPTIONal
A7B19_RS30970	COG0254	rRNA binding
A7B19_RS30975	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
A7B19_RS30980	COG2890	protein-(glutamine-N5) methyltransferase activity
A7B19_RS30990	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A7B19_RS30995	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
A7B19_RS31015	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A7B19_RS31020	COG1250	3-hydroxyacyl-CoA dehydrogenase
A7B19_RS31040	COG0604	alcohol dehydrogenase
A7B19_RS31040	COG3321	synthase
A7B19_RS31065	COG0604	alcohol dehydrogenase
A7B19_RS31065	COG3321	synthase
A7B19_RS31070	COG1819	glycosyl
A7B19_RS31080	COG1819	glycosyl
A7B19_RS31125	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A7B19_RS31155	COG0019	diaminopimelate decarboxylase activity
A7B19_RS31170	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A7B19_RS31185	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
A7B19_RS31190	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
A7B19_RS31195	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
A7B19_RS31200	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
A7B19_RS31205	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
A7B19_RS31210	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
A7B19_RS31215	COG0355	proton-transporting ATP synthase activity, rotational mechanism
A7B19_RS31225	COG2197	response regulator
A7B19_RS31260	COG1250	3-hydroxyacyl-CoA dehydrogenase
A7B19_RS31275	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
A7B19_RS31325	COG0183	Belongs to the thiolase family
A7B19_RS31335	COG0745	RESPONSE REGULATOR receiver
A7B19_RS31340	COG2205	protein histidine kinase activity
A7B19_RS31390	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A7B19_RS31390	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A7B19_RS31430	COG0542	response to heat
A7B19_RS31440	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
A7B19_RS31445	COG0857	belongs to the CobB CobQ family
A7B19_RS31445	COG0280	phosphate acetyltransferase
A7B19_RS31450	COG0205	6-phosphofructokinase activity
A7B19_RS31465	COG3833	ABC-type maltose transport systems, permease component
A7B19_RS31470	COG1316	TRANSCRIPTIONal
A7B19_RS31490	COG1595	DNA-templated transcription, initiation
A7B19_RS31495	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A7B19_RS31515	COG0800	Aldolase
A7B19_RS31530	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A7B19_RS31590	COG0577	efflux transmembrane transporter activity
A7B19_RS31590	COG1136	(ABC) transporter
A7B19_RS31635	COG1595	DNA-templated transcription, initiation
A7B19_RS31645	COG1175	transmembrane transport
A7B19_RS31655	COG3469	chitinase activity
A7B19_RS31660	COG4565	transcriptional regulatory protein
A7B19_RS31665	COG5000	phosphorelay sensor kinase activity
A7B19_RS31670	COG1301	dicarboxylic acid transport
A7B19_RS31680	COG3629	intracellular signal transduction
A7B19_RS31680	COG3903	Transcriptional regulator
A7B19_RS31680	COG3629	intracellular signal transduction
A7B19_RS31680	COG3903	Transcriptional regulator
A7B19_RS31685	COG2319	Wd-40 repeat
A7B19_RS31685	COG4249	Peptidase C14 caspase catalytic subunit p20
A7B19_RS31695	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
A7B19_RS31700	COG3281	Trehalose synthase
A7B19_RS31710	COG0366	Alpha amylase catalytic
A7B19_RS31720	COG5297	Belongs to the glycosyl hydrolase family 6
A7B19_RS31730	COG3401	FG-GAP repeat protein
A7B19_RS31740	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
A7B19_RS31765	COG3340	Belongs to the peptidase S51 family
A7B19_RS31770	COG1414	Transcriptional regulator
A7B19_RS31800	COG1132	(ABC) transporter
A7B19_RS31805	COG1132	(ABC) transporter
A7B19_RS31815	COG1376	ErfK ybiS ycfS ynhG family protein
A7B19_RS31925	COG1760	l-serine dehydratase
A7B19_RS31930	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
A7B19_RS31940	COG0404	The glycine cleavage system catalyzes the degradation of glycine
A7B19_RS31965	COG4166	transmembrane transport
A7B19_RS31975	COG0444	Belongs to the ABC transporter superfamily
A7B19_RS31980	COG4608	Belongs to the ABC transporter superfamily
A7B19_RS31985	COG2860	membrane
A7B19_RS32090	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
A7B19_RS32100	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A7B19_RS32105	COG0154	amidase activity
A7B19_RS32115	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A7B19_RS32135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A7B19_RS32145	COG3511	phospholipase C
A7B19_RS32150	COG2409	Drug exporters of the RND superfamily
A7B19_RS32155	COG2133	pyrroloquinoline quinone binding
A7B19_RS32160	COG0667	Aldo Keto reductase
A7B19_RS32180	COG0440	acetolactate synthase activity
A7B19_RS32185	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
A7B19_RS32220	COG0506	proline dehydrogenase activity
A7B19_RS32225	COG1012	belongs to the aldehyde dehydrogenase family
A7B19_RS32235	COG0473	3-isopropylmalate dehydrogenase activity
A7B19_RS32240	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A7B19_RS32245	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A7B19_RS32255	COG5492	domain, Protein
A7B19_RS32260	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A7B19_RS32280	COG2018	Roadblock/LC7 domain
A7B19_RS32285	COG5002	protein histidine kinase activity
A7B19_RS32290	COG0179	Fumarylacetoacetate (FAA) hydrolase
A7B19_RS32295	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A7B19_RS32340	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
A7B19_RS32345	COG0066	3-isopropylmalate dehydratase activity
A7B19_RS32355	COG0776	regulation of translation
A7B19_RS32365	COG1920	GTP binding
A7B19_RS32375	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
A7B19_RS32380	COG1181	Belongs to the D-alanine--D-alanine ligase family
A7B19_RS32395	COG0351	phosphomethylpyrimidine kinase
A7B19_RS32400	COG0227	Belongs to the bacterial ribosomal protein bL28 family
A7B19_RS32405	COG1461	Dihydroxyacetone kinase
A7B19_RS32415	COG0742	ribosomal rna small subunit methyltransferase
A7B19_RS32420	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
A7B19_RS32435	COG0333	Belongs to the bacterial ribosomal protein bL32 family
A7B19_RS32440	COG0571	ribonuclease III activity
A7B19_RS32445	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
A7B19_RS32450	COG1733	regulation of RNA biosynthetic process
A7B19_RS32460	COG1254	Belongs to the acylphosphatase family
A7B19_RS32475	COG0477	Major facilitator Superfamily
A7B19_RS32495	COG4585	Histidine kinase
A7B19_RS32500	COG2197	response regulator
A7B19_RS32530	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
A7B19_RS32545	COG0442	prolyl-tRNA aminoacylation
A7B19_RS32555	COG0228	four-way junction DNA binding
A7B19_RS32560	COG1837	Belongs to the UPF0109 family
A7B19_RS32565	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
A7B19_RS32570	COG0336	Belongs to the RNA methyltransferase TrmD family
A7B19_RS32575	COG0335	large ribosomal subunit rRNA binding
A7B19_RS32590	COG0681	Belongs to the peptidase S26 family
A7B19_RS32595	COG0681	Belongs to the peptidase S26 family
A7B19_RS32600	COG1051	belongs to the nudix hydrolase family
A7B19_RS32610	COG0792	nuclease activity
A7B19_RS32625	COG1191	sigma factor activity
A7B19_RS32635	COG4942	peptidase
A7B19_RS32635	COG1388	LysM domain
A7B19_RS32640	COG0052	Belongs to the universal ribosomal protein uS2 family
A7B19_RS32645	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
A7B19_RS32650	COG0528	UMP kinase activity
A7B19_RS32655	COG0233	cytoplasmic translational termination
A7B19_RS32660	COG0575	Belongs to the CDS family
A7B19_RS32665	COG0820	rRNA (adenine-C2-)-methyltransferase activity
A7B19_RS32680	COG3842	ATPase activity
A7B19_RS32700	COG0028	Belongs to the TPP enzyme family
A7B19_RS32715	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A7B19_RS32725	COG1012	belongs to the aldehyde dehydrogenase family
A7B19_RS32735	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
A7B19_RS32750	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
A7B19_RS32755	COG3842	ATPase activity
A7B19_RS32760	COG1176	ABC-type spermidine putrescine transport system, permease component I
A7B19_RS32765	COG1177	transmembrane transport
A7B19_RS32770	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A7B19_RS32790	COG2508	Transcriptional regulator
A7B19_RS32795	COG1012	belongs to the aldehyde dehydrogenase family
A7B19_RS32800	COG1472	Belongs to the glycosyl hydrolase 3 family
A7B19_RS32810	COG4209	transmembrane transport
A7B19_RS32815	COG0395	ABC-type sugar transport system, permease component
A7B19_RS32845	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
A7B19_RS32850	COG0750	zinc metalloprotease
A7B19_RS32855	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
A7B19_RS32870	COG0442	prolyl-tRNA aminoacylation
A7B19_RS32890	COG0779	Required for maturation of 30S ribosomal subunits
A7B19_RS32905	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
A7B19_RS32915	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
A7B19_RS32920	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
A7B19_RS32930	COG0455	bacterial-type flagellum organization
A7B19_RS32955	COG1404	Belongs to the peptidase S8 family
A7B19_RS33005	COG0515	serine threonine protein kinase
A7B19_RS33005	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A7B19_RS33020	COG0154	amidase activity
A7B19_RS33025	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
A7B19_RS33030	COG1185	polyribonucleotide nucleotidyltransferase activity
A7B19_RS33035	COG0612	Peptidase, M16
A7B19_RS33040	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
A7B19_RS33060	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
A7B19_RS33065	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A7B19_RS33070	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
A7B19_RS33100	COG2770	Histidine kinase
A7B19_RS33100	COG2208	phosphoserine phosphatase activity
A7B19_RS33105	COG2205	protein histidine kinase activity
A7B19_RS33105	COG3437	response regulator, receiver
A7B19_RS33105	COG3850	Histidine kinase
A7B19_RS33105	COG4999	Histidine kinase
A7B19_RS33125	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A7B19_RS33135	COG1546	Belongs to the CinA family
A7B19_RS33135	COG1058	Belongs to the CinA family
A7B19_RS33140	COG1396	sequence-specific DNA binding
A7B19_RS33150	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS33155	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
A7B19_RS33160	COG1201	RNA secondary structure unwinding
A7B19_RS33205	COG0765	amino acid transport
A7B19_RS33210	COG0765	amino acid transport
A7B19_RS33220	COG1126	abc transporter atp-binding protein
A7B19_RS33230	COG2205	protein histidine kinase activity
A7B19_RS33240	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A7B19_RS33260	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
A7B19_RS33270	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
A7B19_RS33275	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A7B19_RS33285	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A7B19_RS33315	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
A7B19_RS33320	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
A7B19_RS33325	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A7B19_RS33330	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A7B19_RS33345	COG0488	(ABC) transporter
A7B19_RS33350	COG0406	alpha-ribazole phosphatase activity
A7B19_RS33360	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
A7B19_RS33390	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A7B19_RS33395	COG2186	Transcriptional regulator
A7B19_RS33400	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
A7B19_RS33425	COG4585	Histidine kinase
A7B19_RS33430	COG2197	response regulator
A7B19_RS33440	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A7B19_RS33445	COG4565	transcriptional regulatory protein
A7B19_RS33450	COG3290	protein histidine kinase activity
A7B19_RS33465	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A7B19_RS33470	COG0612	Peptidase, M16
A7B19_RS33485	COG1802	Transcriptional regulator
A7B19_RS33490	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A7B19_RS33510	COG1435	thymidine kinase activity
A7B19_RS33540	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
A7B19_RS33545	COG0483	inositol monophosphate 1-phosphatase activity
A7B19_RS33550	COG0745	RESPONSE REGULATOR receiver
A7B19_RS33555	COG2205	protein histidine kinase activity
A7B19_RS33580	COG0756	dUTP diphosphatase activity
A7B19_RS33600	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
A7B19_RS33605	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
A7B19_RS33610	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
A7B19_RS33640	COG0569	domain protein
A7B19_RS33670	COG0531	amino acid
A7B19_RS33675	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A7B19_RS33745	COG2040	homocysteine
A7B19_RS33755	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
A7B19_RS33760	COG4977	sequence-specific DNA binding
A7B19_RS33800	COG1024	Enoyl-CoA hydratase
A7B19_RS33805	COG1902	pentaerythritol trinitrate reductase activity
A7B19_RS33865	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
A7B19_RS33890	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
A7B19_RS33915	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A7B19_RS33940	COG1653	transport
A7B19_RS33945	COG1175	transmembrane transport
A7B19_RS33950	COG0395	ABC-type sugar transport system, permease component
A7B19_RS33960	COG4213	ABC transporter substrate-binding protein
A7B19_RS33970	COG4214	carbohydrate transport
A7B19_RS33975	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
A7B19_RS33980	COG0531	amino acid
A7B19_RS33995	COG1024	Enoyl-CoA hydratase
A7B19_RS33995	COG1250	3-hydroxyacyl-CoA dehydrogenase
A7B19_RS34000	COG0183	Belongs to the thiolase family
A7B19_RS34020	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
A7B19_RS34025	COG0446	pyridine nucleotide-disulphide oxidoreductase
A7B19_RS34030	COG2271	Major facilitator Superfamily
A7B19_RS34045	COG1414	Transcriptional regulator
A7B19_RS34050	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
A7B19_RS34055	COG3253	May function as heme-dependent peroxidase
A7B19_RS34075	COG3220	belongs to the UPF0276 family
A7B19_RS34120	COG0745	RESPONSE REGULATOR receiver
A7B19_RS34125	COG5002	protein histidine kinase activity
A7B19_RS34155	COG1136	(ABC) transporter
A7B19_RS34185	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
A7B19_RS34190	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A7B19_RS34205	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A7B19_RS34210	COG0583	DNA-binding transcription factor activity
A7B19_RS34255	COG1119	ATPase activity
A7B19_RS34260	COG2188	Transcriptional regulator
A7B19_RS34325	COG1136	(ABC) transporter
A7B19_RS34325	COG0577	efflux transmembrane transporter activity
A7B19_RS34365	COG2146	nitrite reductase [NAD(P)H] activity
A7B19_RS34365	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A7B19_RS34375	COG0243	molybdopterin cofactor binding
A7B19_RS34380	COG2223	nitrite transmembrane transporter activity
A7B19_RS34400	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A7B19_RS34405	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A7B19_RS34420	COG1175	transmembrane transport
A7B19_RS34455	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
A7B19_RS34470	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A7B19_RS34475	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
A7B19_RS34495	COG0529	Catalyzes the synthesis of activated sulfate
A7B19_RS34500	COG0175	sulfate reduction
A7B19_RS34545	COG1162	GTPase activity
A7B19_RS34550	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A7B19_RS34560	COG0028	Belongs to the TPP enzyme family
A7B19_RS34565	COG0596	Alpha beta hydrolase
A7B19_RS34575	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
A7B19_RS34620	COG1802	Transcriptional regulator
A7B19_RS34655	COG0823	Involved in the tonB-independent uptake of proteins
A7B19_RS34665	COG0598	Magnesium transport protein CorA
A7B19_RS34675	COG2197	response regulator
A7B19_RS34680	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A7B19_RS34685	COG0318	PFAM AMP-dependent synthetase and ligase
A7B19_RS34695	COG0508	dehydrogenase complex catalyzes the overall conversion of
A7B19_RS34695	COG0596	Alpha beta hydrolase
A7B19_RS34740	COG2133	pyrroloquinoline quinone binding
A7B19_RS34740	COG5183	chlorophyll binding
A7B19_RS34745	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
A7B19_RS34750	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
A7B19_RS34760	COG1414	Transcriptional regulator
A7B19_RS34765	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
A7B19_RS34770	COG4266	Belongs to the allantoicase family
A7B19_RS34830	COG0800	Aldolase
A7B19_RS34850	COG1595	DNA-templated transcription, initiation
A7B19_RS34875	COG1874	Beta-galactosidase
A7B19_RS34885	COG0601	transmembrane transport
A7B19_RS34890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A7B19_RS34895	COG0444	Belongs to the ABC transporter superfamily
A7B19_RS34905	COG2188	Transcriptional regulator
A7B19_RS34925	COG1940	carbohydrate kinase activity
A7B19_RS34935	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
A7B19_RS34960	COG1126	abc transporter atp-binding protein
A7B19_RS34965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A7B19_RS34970	COG0765	amino acid transport
A7B19_RS34990	COG0405	Gamma-glutamyltransferase
A7B19_RS35005	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A7B19_RS35010	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
A7B19_RS35040	COG1940	carbohydrate kinase activity
A7B19_RS35040	COG1846	Transcriptional regulator
A7B19_RS35045	COG1082	Xylose isomerase domain protein TIM barrel
A7B19_RS35055	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS35065	COG1129	ABC transporter
A7B19_RS35070	COG1879	ABC-type sugar transport system periplasmic component
A7B19_RS35075	COG1172	Belongs to the binding-protein-dependent transport system permease family
A7B19_RS35085	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
A7B19_RS35090	COG3958	Transketolase
A7B19_RS35095	COG3959	Transketolase, thiamine diphosphate binding domain
A7B19_RS35120	COG0181	hydroxymethylbilane synthase activity
A7B19_RS35155	COG1595	DNA-templated transcription, initiation
A7B19_RS35165	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
A7B19_RS35205	COG1929	Belongs to the glycerate kinase type-1 family
A7B19_RS35225	COG0688	phosphatidylethanolamine metabolic process
A7B19_RS35230	COG1960	acyl-CoA dehydrogenase activity
A7B19_RS35240	COG2301	Belongs to the HpcH HpaI aldolase family
A7B19_RS35245	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A7B19_RS35245	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A7B19_RS35260	COG1082	Xylose isomerase domain protein TIM barrel
A7B19_RS35265	COG1309	transcriptional regulator
A7B19_RS35300	COG2208	phosphoserine phosphatase activity
A7B19_RS35300	COG1366	Belongs to the anti-sigma-factor antagonist family
A7B19_RS35300	COG2172	sigma factor antagonist activity
A7B19_RS35310	COG2362	D-Aminopeptidase
A7B19_RS35315	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A7B19_RS35345	COG2226	methyltransferase
A7B19_RS35370	COG0693	protein deglycase activity
A7B19_RS35380	COG0028	Belongs to the TPP enzyme family
A7B19_RS35385	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A7B19_RS35445	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A7B19_RS35460	COG0662	Cupin 2, conserved barrel domain protein
A7B19_RS35480	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
A7B19_RS35540	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A7B19_RS35550	COG0596	Alpha beta hydrolase
A7B19_RS35595	COG3631	Ketosteroid isomerase-related protein
A7B19_RS35600	COG1309	transcriptional regulator
A7B19_RS35615	COG1733	regulation of RNA biosynthetic process
A7B19_RS35650	COG4251	negative regulation of phosphorylation
A7B19_RS35655	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
A7B19_RS35660	COG2205	protein histidine kinase activity
A7B19_RS35675	COG0531	amino acid
A7B19_RS35700	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS35715	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A7B19_RS35755	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A7B19_RS35755	COG0574	Belongs to the PEP-utilizing enzyme family
A7B19_RS35770	COG2072	flavoprotein involved in K transport
A7B19_RS35790	COG2130	NADP-dependent
A7B19_RS35800	COG2409	Drug exporters of the RND superfamily
A7B19_RS35805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A7B19_RS35825	COG0675	Transposase, IS605 OrfB family
A7B19_RS35830	COG2154	pterin-4-alpha-carbinolamine dehydratase
A7B19_RS35845	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A7B19_RS35850	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A7B19_RS35875	COG4106	trans-aconitate 2-methyltransferase activity
A7B19_RS35885	COG0656	L-ascorbic acid biosynthetic process
A7B19_RS35895	COG1022	Amp-dependent synthetase and ligase
A7B19_RS35900	COG0583	DNA-binding transcription factor activity
A7B19_RS35925	COG1846	Transcriptional regulator
A7B19_RS35955	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS35965	COG1309	transcriptional regulator
A7B19_RS35970	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
A7B19_RS35985	COG1940	carbohydrate kinase activity
A7B19_RS35990	COG1129	ABC transporter
A7B19_RS35995	COG1172	Belongs to the binding-protein-dependent transport system permease family
A7B19_RS36000	COG1879	ABC-type sugar transport system periplasmic component
A7B19_RS36005	COG0673	inositol 2-dehydrogenase activity
A7B19_RS36075	COG1804	L-carnitine dehydratase bile acid-inducible protein F
A7B19_RS36105	COG3693	PFAM glycoside hydrolase, family 10
A7B19_RS36130	COG2186	Transcriptional regulator
A7B19_RS36150	COG0395	ABC-type sugar transport system, permease component
A7B19_RS36165	COG3507	Belongs to the glycosyl hydrolase 43 family
A7B19_RS36220	COG1982	Orn Lys Arg decarboxylase major
A7B19_RS36255	COG1312	Catalyzes the dehydration of D-mannonate
A7B19_RS36265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A7B19_RS36270	COG0601	transmembrane transport
A7B19_RS36275	COG0747	negative chemotaxis
A7B19_RS36280	COG0673	inositol 2-dehydrogenase activity
A7B19_RS36285	COG1940	carbohydrate kinase activity
A7B19_RS36285	COG1846	Transcriptional regulator
A7B19_RS36295	COG1021	2,3-dihydroxybenzoate-AMP ligase
A7B19_RS36315	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A7B19_RS36320	COG0318	PFAM AMP-dependent synthetase and ligase
A7B19_RS36340	COG0477	Major facilitator Superfamily
A7B19_RS36355	COG0745	RESPONSE REGULATOR receiver
A7B19_RS36365	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A7B19_RS36365	COG2070	2-Nitropropane dioxygenase
A7B19_RS36375	COG0367	asparagine synthase
A7B19_RS36380	COG4221	oxidoreductase activity
A7B19_RS36380	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A7B19_RS36380	COG0300	oxidoreductase activity
A7B19_RS36380	COG3321	synthase
A7B19_RS36385	COG4221	oxidoreductase activity
A7B19_RS36385	COG3321	synthase
A7B19_RS36385	COG0300	oxidoreductase activity
A7B19_RS36385	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A7B19_RS36390	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A7B19_RS36390	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS36390	COG3321	synthase
A7B19_RS36390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A7B19_RS36390	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A7B19_RS36420	COG0395	ABC-type sugar transport system, permease component
A7B19_RS36425	COG1175	transmembrane transport
A7B19_RS36445	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A7B19_RS36470	COG0583	DNA-binding transcription factor activity
A7B19_RS36490	COG1733	regulation of RNA biosynthetic process
A7B19_RS36530	COG0745	RESPONSE REGULATOR receiver
A7B19_RS36540	COG2409	Drug exporters of the RND superfamily
A7B19_RS36550	COG4948	Mandelate Racemase Muconate Lactonizing
A7B19_RS36555	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A7B19_RS36565	COG1301	dicarboxylic acid transport
A7B19_RS36575	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A7B19_RS36580	COG1414	Transcriptional regulator
A7B19_RS36590	COG1404	Belongs to the peptidase S8 family
A7B19_RS36600	COG0531	amino acid
A7B19_RS36605	COG1012	belongs to the aldehyde dehydrogenase family
A7B19_RS36650	COG1515	deoxyribonuclease V activity
A7B19_RS36660	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A7B19_RS36670	COG1804	L-carnitine dehydratase bile acid-inducible protein F
A7B19_RS36675	COG0183	Belongs to the thiolase family
A7B19_RS36680	COG1024	Enoyl-CoA hydratase
A7B19_RS36680	COG1250	3-hydroxyacyl-CoA dehydrogenase
A7B19_RS36695	COG3250	beta-galactosidase activity
A7B19_RS36710	COG2936	dipeptidyl-peptidase activity
A7B19_RS36720	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A7B19_RS36730	COG0488	(ABC) transporter
A7B19_RS36735	COG2183	response to ionizing radiation
A7B19_RS36745	COG1024	Enoyl-CoA hydratase
A7B19_RS36755	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
A7B19_RS36800	COG1134	teichoic acid transport
A7B19_RS36810	COG1562	ergosterol biosynthetic process
A7B19_RS36820	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
A7B19_RS36830	COG1657	PFAM Prenyltransferase squalene oxidase
A7B19_RS36845	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
A7B19_RS36860	COG2365	Tyrosine phosphatase family
A7B19_RS36870	COG2755	lipolytic protein G-D-S-L family
A7B19_RS36970	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
A7B19_RS36975	COG0531	amino acid
A7B19_RS36990	COG1012	belongs to the aldehyde dehydrogenase family
A7B19_RS37015	COG1404	Belongs to the peptidase S8 family
A7B19_RS37030	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
A7B19_RS37040	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
A7B19_RS37045	COG0291	Belongs to the bacterial ribosomal protein bL35 family
A7B19_RS37050	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
A7B19_RS37055	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A7B19_RS37060	COG5002	protein histidine kinase activity
A7B19_RS37065	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
A7B19_RS37070	COG0072	phenylalanine-tRNA ligase activity
A7B19_RS37070	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A7B19_RS37085	COG0494	nUDIX hydrolase
A7B19_RS37095	COG1285	pathogenesis
A7B19_RS37110	COG1649	PFAM Uncharacterised BCR, COG1649
A7B19_RS37125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A7B19_RS37145	COG0077	Prephenate dehydratase
A7B19_RS37160	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A7B19_RS37160	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS37160	COG3321	synthase
A7B19_RS37160	COG0300	oxidoreductase activity
A7B19_RS37160	COG0318	PFAM AMP-dependent synthetase and ligase
A7B19_RS37170	COG4941	Belongs to the sigma-70 factor family
A7B19_RS37185	COG2378	regulation of single-species biofilm formation
A7B19_RS37220	COG1053	succinate dehydrogenase
A7B19_RS37230	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
A7B19_RS37235	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
A7B19_RS37240	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
A7B19_RS37245	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A7B19_RS37250	COG1438	arginine binding
A7B19_RS37255	COG0385	Bile acid
A7B19_RS37340	COG0137	argininosuccinate synthase activity
A7B19_RS37345	COG0165	Argininosuccinate lyase
A7B19_RS37360	COG0318	PFAM AMP-dependent synthetase and ligase
A7B19_RS37360	COG0204	Acyl-transferase
A7B19_RS37395	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A7B19_RS37400	COG2011	ABC-type metal ion transport system permease component
A7B19_RS37405	COG1464	Belongs to the NlpA lipoprotein family
A7B19_RS37420	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
A7B19_RS37425	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
A7B19_RS37425	COG1648	precorrin-2 dehydrogenase activity
A7B19_RS37615	COG4974	Belongs to the 'phage' integrase family
A7B19_RS37945	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A7B19_RS37960	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
A7B19_RS38045	COG2359	stage V sporulation protein S
A7B19_RS38120	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A7B19_RS38120	COG0515	serine threonine protein kinase
A7B19_RS38160	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A7B19_RS38205	COG1653	transport
A7B19_RS38210	COG1175	transmembrane transport
A7B19_RS38215	COG0395	ABC-type sugar transport system, permease component
A7B19_RS38245	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A7B19_RS38280	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A7B19_RS38285	COG1560	Kdo2-lipid A biosynthetic process
A7B19_RS38290	COG0438	transferase activity, transferring glycosyl groups
A7B19_RS38300	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
A7B19_RS38305	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
A7B19_RS38310	COG0217	transcriptional regulatory protein
A7B19_RS38315	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
A7B19_RS38320	COG0632	four-way junction helicase activity
A7B19_RS38325	COG2255	four-way junction helicase activity
A7B19_RS38335	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A7B19_RS38340	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A7B19_RS38345	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A7B19_RS38350	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A7B19_RS38355	COG1196	nuclear chromosome segregation
A7B19_RS38360	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A7B19_RS38390	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
A7B19_RS38405	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A7B19_RS38410	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
A7B19_RS38420	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
A7B19_RS38425	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
A7B19_RS38430	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
A7B19_RS38435	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
A7B19_RS38445	COG0006	proline dipeptidase activity
A7B19_RS38450	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
A7B19_RS38455	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A7B19_RS38465	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
A7B19_RS38470	COG0540	Belongs to the ATCase OTCase family
A7B19_RS38475	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
A7B19_RS38485	COG0505	Belongs to the CarA family
A7B19_RS38490	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
A7B19_RS38495	COG0167	dihydroorotate dehydrogenase activity
A7B19_RS38500	COG0284	orotidine-5'-phosphate decarboxylase activity
A7B19_RS38525	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
A7B19_RS38540	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
A7B19_RS38545	COG1132	(ABC) transporter
A7B19_RS38555	COG2838	Isocitrate dehydrogenase
A7B19_RS38565	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
A7B19_RS38570	COG2390	Transcriptional regulator
A7B19_RS38590	COG0531	amino acid
A7B19_RS38600	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A7B19_RS38625	COG2233	PERMEase
A7B19_RS38635	COG0738	Major facilitator superfamily
A7B19_RS38655	COG3201	nicotinamide mononucleotide transporter
A7B19_RS38660	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A7B19_RS38660	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A7B19_RS38665	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
A7B19_RS38670	COG0140	phosphoribosyl-ATP diphosphatase activity
A7B19_RS38675	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
A7B19_RS38730	COG0589	response to stress
A7B19_RS38735	COG0516	GMP reductase activity
A7B19_RS38735	COG0517	IMP dehydrogenase activity
A7B19_RS38745	COG0517	IMP dehydrogenase activity
A7B19_RS38755	COG1937	Protein conserved in bacteria
A7B19_RS38760	COG2217	Heavy metal translocating P-type atpase
A7B19_RS38800	COG2326	polyphosphate kinase activity
A7B19_RS38805	COG0045	succinate-CoA ligase (ADP-forming) activity
A7B19_RS38805	COG1042	CoA-binding domain protein
A7B19_RS38805	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A7B19_RS38825	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
A7B19_RS38840	COG1017	nitric oxide dioxygenase activity
A7B19_RS38840	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A7B19_RS38845	COG0745	RESPONSE REGULATOR receiver
A7B19_RS38850	COG2205	protein histidine kinase activity
A7B19_RS38860	COG1132	(ABC) transporter
A7B19_RS38885	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
A7B19_RS38890	COG1619	proteins homologs of microcin C7 resistance protein MccF
A7B19_RS38895	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A7B19_RS38900	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A7B19_RS38960	COG1203	CRISPR-associated helicase, Cas3
A7B19_RS38970	COG1518	maintenance of DNA repeat elements
A7B19_RS38975	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
A7B19_RS39095	COG0305	Participates in initiation and elongation during chromosome replication
A7B19_RS39165	COG0791	NLP P60 protein
A7B19_RS39185	COG3629	intracellular signal transduction
A7B19_RS39185	COG3903	Transcriptional regulator
A7B19_RS39205	COG0515	serine threonine protein kinase
A7B19_RS39215	COG0534	Mate efflux family protein
A7B19_RS39230	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS39240	COG3835	regulator
A7B19_RS39250	COG0071	Belongs to the small heat shock protein (HSP20) family
A7B19_RS39255	COG5001	Diguanylate cyclase
A7B19_RS39265	COG1012	belongs to the aldehyde dehydrogenase family
A7B19_RS39280	COG1960	acyl-CoA dehydrogenase activity
A7B19_RS39290	COG1522	sequence-specific DNA binding
A7B19_RS39305	COG0463	Glycosyl transferase, family 2
A7B19_RS39315	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A7B19_RS39320	COG1006	Multisubunit Na H antiporter MnhC subunit
A7B19_RS39325	COG2111	Na H antiporter
A7B19_RS39355	COG2186	Transcriptional regulator
A7B19_RS39380	COG1940	carbohydrate kinase activity
A7B19_RS39380	COG1846	Transcriptional regulator
A7B19_RS39390	COG0395	ABC-type sugar transport system, permease component
A7B19_RS39425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A7B19_RS39430	COG0765	amino acid transport
A7B19_RS39435	COG0765	amino acid transport
A7B19_RS39440	COG1126	abc transporter atp-binding protein
A7B19_RS39450	COG0395	ABC-type sugar transport system, permease component
A7B19_RS39455	COG1175	transmembrane transport
A7B19_RS39485	COG0738	Major facilitator superfamily
A7B19_RS39495	COG0789	Transcriptional regulator
A7B19_RS39520	COG1556	Lactate utilization protein
A7B19_RS39525	COG1139	Iron-sulfur cluster binding protein
A7B19_RS39530	COG0247	lactate metabolic process
A7B19_RS39550	COG3250	beta-galactosidase activity
A7B19_RS39555	COG1129	ABC transporter
A7B19_RS39560	COG1172	Belongs to the binding-protein-dependent transport system permease family
A7B19_RS39575	COG3254	rhamnose metabolic process
A7B19_RS39585	COG1609	Transcriptional regulator
A7B19_RS39595	COG0583	DNA-binding transcription factor activity
A7B19_RS39600	COG0640	Transcriptional regulator
A7B19_RS39610	COG1609	Transcriptional regulator
A7B19_RS39645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A7B19_RS39655	COG1116	anion transmembrane transporter activity
A7B19_RS39660	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A7B19_RS39665	COG0432	Pfam Uncharacterised protein family UPF0047
A7B19_RS39675	COG3903	Transcriptional regulator
A7B19_RS39675	COG3629	intracellular signal transduction
A7B19_RS39700	COG3629	intracellular signal transduction
A7B19_RS39720	COG2205	protein histidine kinase activity
A7B19_RS39730	COG0542	response to heat
A7B19_RS39760	COG4977	sequence-specific DNA binding
A7B19_RS39770	COG4585	Histidine kinase
A7B19_RS39790	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
A7B19_RS39795	COG0745	RESPONSE REGULATOR receiver
A7B19_RS39800	COG2205	protein histidine kinase activity
A7B19_RS39855	COG3251	PFAM MbtH domain protein
A7B19_RS39890	COG1136	(ABC) transporter
A7B19_RS39890	COG0577	efflux transmembrane transporter activity
A7B19_RS39935	COG0235	Class ii aldolase
A7B19_RS39955	COG2080	2 iron, 2 sulfur cluster binding
A7B19_RS39960	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
A7B19_RS39965	COG1529	Aldehyde oxidase and xanthine dehydrogenase
A7B19_RS39975	COG0145	ligase activity
A7B19_RS40010	COG1522	sequence-specific DNA binding
A7B19_RS40020	COG2706	6-phosphogluconolactonase activity
A7B19_RS40040	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
A7B19_RS40050	COG0640	Transcriptional regulator
A7B19_RS40070	COG1309	transcriptional regulator
A7B19_RS40075	COG0583	DNA-binding transcription factor activity
A7B19_RS40085	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A7B19_RS40120	COG0431	NADPH-dependent FMN reductase
A7B19_RS40125	COG0277	FAD linked oxidase domain protein
A7B19_RS40140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A7B19_RS40145	COG2358	TRAP transporter, solute receptor (TAXI family
A7B19_RS40150	COG1116	anion transmembrane transporter activity
A7B19_RS40155	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A7B19_RS40170	COG0583	DNA-binding transcription factor activity
A7B19_RS40185	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
A7B19_RS40195	COG0183	Belongs to the thiolase family
A7B19_RS40200	COG0583	DNA-binding transcription factor activity
A7B19_RS40205	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A7B19_RS40215	COG0577	efflux transmembrane transporter activity
A7B19_RS40215	COG1136	(ABC) transporter
A7B19_RS40220	COG0577	efflux transmembrane transporter activity
A7B19_RS40220	COG1136	(ABC) transporter
A7B19_RS40225	COG4585	Histidine kinase
A7B19_RS40230	COG2197	response regulator
A7B19_RS40250	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
A7B19_RS40290	COG0671	phosphoesterase, PA-phosphatase related
A7B19_RS40305	COG1396	sequence-specific DNA binding
A7B19_RS40310	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
A7B19_RS40325	COG0456	acetyltransferase
A7B19_RS40330	COG0584	glycerophosphoryl diester phosphodiesterase
A7B19_RS40370	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
A7B19_RS40405	COG0515	serine threonine protein kinase
A7B19_RS40405	COG2815	serine threonine protein kinase
A7B19_RS40410	COG3345	alpha-galactosidase
A7B19_RS40420	COG1175	transmembrane transport
A7B19_RS40425	COG0395	ABC-type sugar transport system, permease component
A7B19_RS40430	COG1660	Displays ATPase and GTPase activities
A7B19_RS40440	COG0445	tRNA wobble uridine modification
A7B19_RS40455	COG4585	Histidine kinase
A7B19_RS40460	COG2197	response regulator
A7B19_RS40485	COG1940	carbohydrate kinase activity
A7B19_RS40525	COG1349	DNA-binding transcription factor activity
A7B19_RS40570	COG3217	Mosc domain protein beta barrel domain protein
A7B19_RS40570	COG0633	Ferredoxin
A7B19_RS40600	COG0494	nUDIX hydrolase
A7B19_RS40605	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS40620	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A7B19_RS40620	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A7B19_RS40620	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
A7B19_RS40625	COG1461	Dihydroxyacetone kinase
A7B19_RS40630	COG2376	Dihydroxyacetone kinase
A7B19_RS40640	COG1960	acyl-CoA dehydrogenase activity
A7B19_RS40660	COG2188	Transcriptional regulator
A7B19_RS40665	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A7B19_RS40670	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
A7B19_RS40675	COG2828	Protein conserved in bacteria
A7B19_RS40685	COG2814	Major facilitator Superfamily
A7B19_RS40695	COG3293	Transposase
A7B19_RS40705	COG0673	inositol 2-dehydrogenase activity
A7B19_RS40715	COG0395	ABC-type sugar transport system, permease component
A7B19_RS40725	COG1653	transport
A7B19_RS40730	COG1609	Transcriptional regulator
A7B19_RS40745	COG4948	Mandelate Racemase Muconate Lactonizing
A7B19_RS40750	COG1175	transmembrane transport
A7B19_RS40755	COG0395	ABC-type sugar transport system, permease component
A7B19_RS40785	COG0477	Major facilitator Superfamily
A7B19_RS40810	COG4221	oxidoreductase activity
A7B19_RS40820	COG3842	ATPase activity
A7B19_RS40845	COG2070	2-Nitropropane dioxygenase
A7B19_RS40855	COG0596	Alpha beta hydrolase
A7B19_RS40900	COG1024	Enoyl-CoA hydratase
A7B19_RS40980	COG0438	transferase activity, transferring glycosyl groups
A7B19_RS41005	COG0723	plastoquinol--plastocyanin reductase activity
A7B19_RS41005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A7B19_RS41010	COG2890	protein-(glutamine-N5) methyltransferase activity
A7B19_RS41020	COG1984	allophanate hydrolase subunit 2
A7B19_RS41025	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
A7B19_RS41030	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
A7B19_RS41035	COG4336	lyase activity
A7B19_RS41040	COG2814	Major facilitator Superfamily
A7B19_RS41050	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
A7B19_RS41075	COG0531	amino acid
A7B19_RS41080	COG1012	belongs to the aldehyde dehydrogenase family
A7B19_RS41105	COG2146	nitrite reductase [NAD(P)H] activity
A7B19_RS41125	COG2018	Roadblock/LC7 domain
A7B19_RS41140	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A7B19_RS41150	COG3842	ATPase activity
A7B19_RS41155	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
A7B19_RS41160	COG1176	ABC-type spermidine putrescine transport system, permease component I
A7B19_RS41165	COG1177	transmembrane transport
A7B19_RS41170	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
A7B19_RS41180	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A7B19_RS41185	COG3835	regulator
A7B19_RS41190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A7B19_RS41195	COG0765	amino acid transport
A7B19_RS41205	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A7B19_RS41215	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A7B19_RS41245	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
A7B19_RS41285	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A7B19_RS41295	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A7B19_RS41295	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A7B19_RS41325	COG0384	phenazine biosynthesis protein PhzF
A7B19_RS41330	COG1695	Transcriptional regulator
A7B19_RS41370	COG0583	DNA-binding transcription factor activity
A7B19_RS41390	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
A7B19_RS41395	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
A7B19_RS41400	COG2197	response regulator
A7B19_RS41405	COG4585	Histidine kinase
A7B19_RS41410	COG2409	Drug exporters of the RND superfamily
A7B19_RS41435	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
A7B19_RS41445	COG2378	regulation of single-species biofilm formation
A7B19_RS41455	COG2318	DinB family
A7B19_RS41475	COG0815	Transfers the fatty acyl group on membrane lipoproteins
A7B19_RS41485	COG1172	Belongs to the binding-protein-dependent transport system permease family
A7B19_RS41500	COG4948	Mandelate Racemase Muconate Lactonizing
A7B19_RS41505	COG2186	Transcriptional regulator
A7B19_RS41510	COG1113	amino acid transport
A7B19_RS41575	COG1113	amino acid transport
A7B19_RS41590	COG0477	Major facilitator Superfamily
A7B19_RS41600	COG4266	Belongs to the allantoicase family
A7B19_RS41605	COG3960	tartronate-semialdehyde synthase activity
A7B19_RS41610	COG2084	Dehydrogenase
A7B19_RS41615	COG3622	Belongs to the hyi family
A7B19_RS41630	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A7B19_RS41635	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
A7B19_RS41640	COG0227	Belongs to the bacterial ribosomal protein bL28 family
A7B19_RS41645	COG0444	Belongs to the ABC transporter superfamily
A7B19_RS41655	COG0601	transmembrane transport
A7B19_RS41675	COG4948	Mandelate Racemase Muconate Lactonizing
A7B19_RS41680	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A7B19_RS41690	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
A7B19_RS41715	COG0493	'glutamate synthase
A7B19_RS41715	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
A7B19_RS41740	COG4566	intracellular signal transduction
A7B19_RS41745	COG3852	Histidine kinase
A7B19_RS41780	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A7B19_RS41785	COG1181	Belongs to the D-alanine--D-alanine ligase family
A7B19_RS41815	COG3552	Protein containing von Willebrand factor type A (VWA) domain
A7B19_RS41820	COG0714	Associated with various cellular activities
A7B19_RS41835	COG0714	Associated with various cellular activities
A7B19_RS41850	COG1595	DNA-templated transcription, initiation
A7B19_RS41875	COG0395	ABC-type sugar transport system, permease component
A7B19_RS41895	COG2186	Transcriptional regulator
A7B19_RS41900	COG1309	transcriptional regulator
A7B19_RS41905	COG0824	Thioesterase
A7B19_RS41905	COG1250	3-hydroxyacyl-CoA dehydrogenase
A7B19_RS41910	COG1960	acyl-CoA dehydrogenase activity
A7B19_RS41915	COG0045	succinate-CoA ligase (ADP-forming) activity
A7B19_RS41965	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
A7B19_RS41970	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A7B19_RS41970	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A7B19_RS41970	COG1703	isobutyryl-CoA mutase activity
A7B19_RS41975	COG0183	Belongs to the thiolase family
A7B19_RS41980	COG1802	Transcriptional regulator
A7B19_RS41990	COG3842	ATPase activity
A7B19_RS42000	COG0028	Belongs to the TPP enzyme family
A7B19_RS42005	COG1960	acyl-CoA dehydrogenase activity
A7B19_RS42010	COG1960	acyl-CoA dehydrogenase activity
A7B19_RS42020	COG1960	acyl-CoA dehydrogenase activity
A7B19_RS42030	COG2226	methyltransferase
A7B19_RS42030	COG1073	alpha beta
A7B19_RS42035	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS42040	COG0318	PFAM AMP-dependent synthetase and ligase
A7B19_RS42045	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS42050	COG0183	Belongs to the thiolase family
A7B19_RS42055	COG1024	Enoyl-CoA hydratase
A7B19_RS42060	COG1063	alcohol dehydrogenase
A7B19_RS42065	COG0277	FAD linked oxidase domain protein
A7B19_RS42065	COG0247	lactate metabolic process
A7B19_RS42070	COG1024	Enoyl-CoA hydratase
A7B19_RS42085	COG0367	asparagine synthase
A7B19_RS42100	COG4221	oxidoreductase activity
A7B19_RS42110	COG1349	DNA-binding transcription factor activity
A7B19_RS42125	COG2132	Multicopper oxidase
A7B19_RS42135	COG0477	Major facilitator Superfamily
A7B19_RS42165	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A7B19_RS42175	COG1937	Protein conserved in bacteria
A7B19_RS42185	COG3507	Belongs to the glycosyl hydrolase 43 family
A7B19_RS42190	COG1609	Transcriptional regulator
A7B19_RS42195	COG3250	beta-galactosidase activity
A7B19_RS42200	COG0667	Aldo Keto reductase
A7B19_RS42205	COG0667	Aldo Keto reductase
A7B19_RS42230	COG3250	beta-galactosidase activity
A7B19_RS42235	COG2814	Major facilitator Superfamily
A7B19_RS42240	COG3250	beta-galactosidase activity
A7B19_RS42245	COG3485	protocatechuate 3,4-dioxygenase
A7B19_RS42250	COG1454	alcohol dehydrogenase
A7B19_RS42255	COG0477	Major facilitator Superfamily
A7B19_RS42265	COG1129	ABC transporter
A7B19_RS42270	COG1172	Belongs to the binding-protein-dependent transport system permease family
A7B19_RS42275	COG1879	ABC-type sugar transport system periplasmic component
A7B19_RS42290	COG3959	Transketolase, thiamine diphosphate binding domain
A7B19_RS42295	COG3958	Transketolase
A7B19_RS42315	COG0183	Belongs to the thiolase family
A7B19_RS42320	COG4221	oxidoreductase activity
A7B19_RS42330	COG0300	oxidoreductase activity
A7B19_RS42340	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A7B19_RS42350	COG1968	undecaprenyl-diphosphatase activity
A7B19_RS42360	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
A7B19_RS42415	COG1832	CoA-binding protein
A7B19_RS42460	COG1739	Uncharacterized protein family UPF0029
A7B19_RS42465	COG0642	Histidine kinase
A7B19_RS42470	COG0745	RESPONSE REGULATOR receiver
A7B19_RS42490	COG0419	ATPase involved in DNA repair
A7B19_RS42495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A7B19_RS42525	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS42530	COG2188	Transcriptional regulator
A7B19_RS42535	COG1940	carbohydrate kinase activity
A7B19_RS42545	COG3663	DNA glycosylase
A7B19_RS42550	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A7B19_RS42595	COG0577	efflux transmembrane transporter activity
A7B19_RS42595	COG1136	(ABC) transporter
A7B19_RS42610	COG2226	methyltransferase
A7B19_RS42615	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
A7B19_RS42620	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A7B19_RS42625	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
A7B19_RS42665	COG0791	NLP P60 protein
A7B19_RS42665	COG0741	lytic transglycosylase activity
A7B19_RS42675	COG0740	serine-type endopeptidase activity
A7B19_RS42685	COG2234	aminopeptidase activity
A7B19_RS42685	COG4935	Belongs to the peptidase S8 family
A7B19_RS42690	COG0831	urea catabolic process
A7B19_RS42695	COG0832	Belongs to the urease beta subunit family
A7B19_RS42700	COG0804	urea catabolic process
A7B19_RS42710	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
A7B19_RS42720	COG1063	alcohol dehydrogenase
A7B19_RS42730	COG1309	transcriptional regulator
A7B19_RS42775	COG0205	6-phosphofructokinase activity
A7B19_RS42780	COG3442	glutamine amidotransferase
A7B19_RS42790	COG0242	peptide deformylase activity
A7B19_RS42800	COG1960	acyl-CoA dehydrogenase activity
A7B19_RS42805	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
A7B19_RS42855	COG0702	epimerase
A7B19_RS42860	COG3631	Ketosteroid isomerase-related protein
A7B19_RS42880	COG0252	asparaginase activity
A7B19_RS42895	COG0402	S-adenosylhomocysteine deaminase activity
A7B19_RS42925	COG1793	dna ligase
A7B19_RS42935	COG1191	sigma factor activity
A7B19_RS42955	COG1349	DNA-binding transcription factor activity
A7B19_RS42960	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
A7B19_RS42965	COG3395	kinase activity
A7B19_RS42975	COG0601	transmembrane transport
A7B19_RS42980	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A7B19_RS42990	COG4608	Belongs to the ABC transporter superfamily
A7B19_RS42995	COG0667	Aldo Keto reductase
A7B19_RS43005	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS43010	COG2356	endonuclease I
A7B19_RS43025	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A7B19_RS43095	COG0395	ABC-type sugar transport system, permease component
A7B19_RS43100	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A7B19_RS43120	COG1953	Uracil, thiamine, allantoin
A7B19_RS43140	COG0242	peptide deformylase activity
A7B19_RS43155	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A7B19_RS43195	COG1063	alcohol dehydrogenase
A7B19_RS43210	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
A7B19_RS43215	COG0277	FAD linked oxidase domain protein
A7B19_RS43225	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
A7B19_RS43235	COG0395	ABC-type sugar transport system, permease component
A7B19_RS43240	COG1175	transmembrane transport
A7B19_RS43250	COG1609	Transcriptional regulator
A7B19_RS43305	COG0640	Transcriptional regulator
A7B19_RS43325	COG1126	abc transporter atp-binding protein
A7B19_RS43330	COG0765	amino acid transport
A7B19_RS43350	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS43365	COG2186	Transcriptional regulator
A7B19_RS43390	COG0514	ATP-dependent DNA helicase (RecQ)
A7B19_RS43395	COG2353	YceI-like domain
A7B19_RS43405	COG1349	DNA-binding transcription factor activity
A7B19_RS43420	COG1063	alcohol dehydrogenase
A7B19_RS43425	COG0395	ABC-type sugar transport system, permease component
A7B19_RS43450	COG1349	DNA-binding transcription factor activity
A7B19_RS43455	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A7B19_RS43460	COG1653	transport
A7B19_RS43470	COG0395	ABC-type sugar transport system, permease component
A7B19_RS43575	COG2353	YceI-like domain
A7B19_RS43590	COG0386	Belongs to the glutathione peroxidase family
A7B19_RS43610	COG1595	DNA-templated transcription, initiation
A7B19_RS43615	COG2301	Belongs to the HpcH HpaI aldolase family
A7B19_RS43620	COG1804	L-carnitine dehydratase bile acid-inducible protein F
A7B19_RS43625	COG0583	DNA-binding transcription factor activity
A7B19_RS43630	COG2851	Citrate transporter
A7B19_RS43640	COG1802	Transcriptional regulator
A7B19_RS43655	COG1012	belongs to the aldehyde dehydrogenase family
A7B19_RS43660	COG4585	Histidine kinase
A7B19_RS43665	COG2197	response regulator
A7B19_RS43675	COG2124	cytochrome p450
A7B19_RS43680	COG0789	Transcriptional regulator
A7B19_RS43695	COG2814	Major facilitator Superfamily
A7B19_RS43705	COG4221	oxidoreductase activity
A7B19_RS43730	COG3835	regulator
A7B19_RS43735	COG2271	Major facilitator Superfamily
A7B19_RS43775	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
A7B19_RS43810	COG2205	protein histidine kinase activity
A7B19_RS43810	COG2972	Histidine kinase
A7B19_RS43840	COG2205	protein histidine kinase activity
A7B19_RS43845	COG0745	RESPONSE REGULATOR receiver
A7B19_RS43850	COG0477	Major facilitator Superfamily
A7B19_RS43865	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
A7B19_RS43950	COG1012	belongs to the aldehyde dehydrogenase family
A7B19_RS43955	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS43960	COG2072	flavoprotein involved in K transport
A7B19_RS44000	COG3321	synthase
A7B19_RS44000	COG0604	alcohol dehydrogenase
A7B19_RS44005	COG3321	synthase
A7B19_RS44005	COG0604	alcohol dehydrogenase
A7B19_RS44015	COG0604	alcohol dehydrogenase
A7B19_RS44015	COG3321	synthase
A7B19_RS44030	COG3321	synthase
A7B19_RS44030	COG0604	alcohol dehydrogenase
A7B19_RS44030	COG3321	synthase
A7B19_RS44030	COG0604	alcohol dehydrogenase
A7B19_RS44040	COG3321	synthase
A7B19_RS44040	COG0604	alcohol dehydrogenase
A7B19_RS44045	COG3321	synthase
A7B19_RS44045	COG0604	alcohol dehydrogenase
A7B19_RS44055	COG1131	(ABC) transporter
A7B19_RS44060	COG3629	intracellular signal transduction
A7B19_RS44060	COG3903	Transcriptional regulator
A7B19_RS44065	COG1819	glycosyl
A7B19_RS44090	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
A7B19_RS44095	COG1819	glycosyl
A7B19_RS44105	COG0604	alcohol dehydrogenase
A7B19_RS44105	COG3321	synthase
A7B19_RS44115	COG3321	synthase
A7B19_RS44115	COG0604	alcohol dehydrogenase
A7B19_RS44155	COG0604	alcohol dehydrogenase
A7B19_RS44160	COG1953	Uracil, thiamine, allantoin
A7B19_RS44205	COG1695	Transcriptional regulator
A7B19_RS44220	COG3293	Transposase
A7B19_RS44270	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A7B19_RS44285	COG0438	transferase activity, transferring glycosyl groups
A7B19_RS44295	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A7B19_RS44300	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
A7B19_RS44320	COG2124	cytochrome p450
A7B19_RS44345	COG0110	maltose O-acetyltransferase activity
A7B19_RS44360	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
A7B19_RS44405	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
A7B19_RS44435	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
A7B19_RS44450	COG3959	Transketolase, thiamine diphosphate binding domain
A7B19_RS44460	COG3360	Dodecin
A7B19_RS44470	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
A7B19_RS44480	COG1960	acyl-CoA dehydrogenase activity
A7B19_RS44495	COG1960	acyl-CoA dehydrogenase activity
A7B19_RS44500	COG1960	acyl-CoA dehydrogenase activity
A7B19_RS44505	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS44510	COG1309	transcriptional regulator
A7B19_RS44515	COG0183	Belongs to the thiolase family
A7B19_RS44555	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
A7B19_RS44575	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
A7B19_RS44585	COG2814	Major facilitator Superfamily
A7B19_RS44610	COG0191	fructose-bisphosphate aldolase activity
A7B19_RS44615	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A7B19_RS44620	COG1349	DNA-binding transcription factor activity
A7B19_RS44625	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
A7B19_RS44645	COG1796	DNA polymerase
A7B19_RS44645	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
A7B19_RS44660	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS44675	COG1472	Belongs to the glycosyl hydrolase 3 family
A7B19_RS44680	COG0477	Major facilitator Superfamily
A7B19_RS44695	COG1802	Transcriptional regulator
A7B19_RS44705	COG0596	Alpha beta hydrolase
A7B19_RS44720	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A7B19_RS44755	COG0443	Heat shock 70 kDa protein
A7B19_RS44760	COG2226	methyltransferase
A7B19_RS44770	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
A7B19_RS44775	COG0477	Major facilitator Superfamily
A7B19_RS44785	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS44790	COG4948	Mandelate Racemase Muconate Lactonizing
A7B19_RS44800	COG2186	Transcriptional regulator
A7B19_RS44815	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A7B19_RS44835	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A7B19_RS44845	COG3224	Antibiotic biosynthesis monooxygenase
A7B19_RS44850	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A7B19_RS44855	COG1834	amidinotransferase
A7B19_RS44860	COG1522	sequence-specific DNA binding
A7B19_RS44865	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A7B19_RS44870	COG3321	synthase
A7B19_RS44870	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS44870	COG0604	alcohol dehydrogenase
A7B19_RS44875	COG0673	inositol 2-dehydrogenase activity
A7B19_RS44885	COG0473	3-isopropylmalate dehydrogenase activity
A7B19_RS44885	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
A7B19_RS44910	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
A7B19_RS44920	COG3525	Glycosyl hydrolase, family 20, catalytic domain
A7B19_RS44925	COG3290	protein histidine kinase activity
A7B19_RS44955	COG2267	carboxylic ester hydrolase activity
A7B19_RS44985	COG0673	inositol 2-dehydrogenase activity
A7B19_RS44990	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS45025	COG1522	sequence-specific DNA binding
A7B19_RS45065	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A7B19_RS45100	COG0765	amino acid transport
A7B19_RS45105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A7B19_RS45120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A7B19_RS45125	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A7B19_RS45130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A7B19_RS45135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A7B19_RS45150	COG0667	Aldo Keto reductase
A7B19_RS45155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A7B19_RS45165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A7B19_RS45180	COG2011	ABC-type metal ion transport system permease component
A7B19_RS45185	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A7B19_RS45190	COG0277	FAD linked oxidase domain protein
A7B19_RS45195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A7B19_RS45205	COG0747	negative chemotaxis
A7B19_RS45215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A7B19_RS45245	COG0583	DNA-binding transcription factor activity
A7B19_RS45255	COG4608	Belongs to the ABC transporter superfamily
A7B19_RS45260	COG0444	Belongs to the ABC transporter superfamily
A7B19_RS45265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A7B19_RS45270	COG0601	transmembrane transport
A7B19_RS45275	COG4166	transmembrane transport
A7B19_RS45285	COG0009	L-threonylcarbamoyladenylate synthase
A7B19_RS45295	COG0531	amino acid
A7B19_RS45310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A7B19_RS45330	COG0583	DNA-binding transcription factor activity
A7B19_RS45335	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
A7B19_RS45350	COG1609	Transcriptional regulator
A7B19_RS45360	COG2814	Major facilitator Superfamily
A7B19_RS45370	COG1082	Xylose isomerase domain protein TIM barrel
A7B19_RS45385	COG3486	L-lysine 6-monooxygenase (NADPH) activity
A7B19_RS45390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7B19_RS45395	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7B19_RS45400	COG1120	ATPase activity
A7B19_RS45405	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A7B19_RS45410	COG1132	(ABC) transporter
A7B19_RS45420	COG1132	(ABC) transporter
A7B19_RS45425	COG2382	esterase
A7B19_RS45440	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
A7B19_RS45445	COG0531	amino acid
A7B19_RS45455	COG0247	lactate metabolic process
A7B19_RS45455	COG0277	FAD linked oxidase domain protein
A7B19_RS45460	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS45470	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A7B19_RS45475	COG1940	carbohydrate kinase activity
A7B19_RS45485	COG1175	transmembrane transport
A7B19_RS45490	COG0395	ABC-type sugar transport system, permease component
A7B19_RS45495	COG0673	inositol 2-dehydrogenase activity
A7B19_RS45505	COG2326	polyphosphate kinase activity
A7B19_RS45520	COG0583	DNA-binding transcription factor activity
A7B19_RS45550	COG0515	serine threonine protein kinase
A7B19_RS45555	COG2267	carboxylic ester hydrolase activity
A7B19_RS45560	COG1609	Transcriptional regulator
A7B19_RS45580	COG0395	ABC-type sugar transport system, permease component
A7B19_RS45590	COG1472	Belongs to the glycosyl hydrolase 3 family
A7B19_RS45600	COG1231	oxidoreductase activity
A7B19_RS45605	COG3961	Belongs to the TPP enzyme family
A7B19_RS45645	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A7B19_RS45650	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
A7B19_RS45655	COG2271	Major facilitator Superfamily
A7B19_RS45670	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
A7B19_RS45720	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS45725	COG3835	regulator
A7B19_RS45730	COG0477	Major facilitator Superfamily
A7B19_RS45765	COG2226	methyltransferase
A7B19_RS45800	COG1349	DNA-binding transcription factor activity
A7B19_RS45810	COG1175	transmembrane transport
A7B19_RS45815	COG0395	ABC-type sugar transport system, permease component
A7B19_RS45820	COG4638	Rieske (2fe-2S)
A7B19_RS45845	COG2271	Major facilitator Superfamily
A7B19_RS45860	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A7B19_RS45870	COG1760	l-serine dehydratase
A7B19_RS45895	COG0477	Major facilitator Superfamily
A7B19_RS45920	COG4249	Peptidase C14 caspase catalytic subunit p20
A7B19_RS45920	COG2319	Wd-40 repeat
A7B19_RS45935	COG0583	DNA-binding transcription factor activity
A7B19_RS45950	COG1301	dicarboxylic acid transport
A7B19_RS45970	COG0535	radical SAM domain protein
A7B19_RS46015	COG0494	nUDIX hydrolase
A7B19_RS46030	COG3485	protocatechuate 3,4-dioxygenase
A7B19_RS46105	COG1295	ribonuclease BN
A7B19_RS46115	COG1309	transcriptional regulator
A7B19_RS46120	COG0483	inositol monophosphate 1-phosphatase activity
A7B19_RS46180	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
A7B19_RS46185	COG4139	cobalamin transport
A7B19_RS46190	COG1012	belongs to the aldehyde dehydrogenase family
A7B19_RS46235	COG1509	lysine 2,3-aminomutase activity
A7B19_RS46325	COG2890	protein-(glutamine-N5) methyltransferase activity
A7B19_RS46360	COG1309	transcriptional regulator
A7B19_RS46370	COG0667	Aldo Keto reductase
A7B19_RS46375	COG1733	regulation of RNA biosynthetic process
A7B19_RS46385	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
A7B19_RS46435	COG0477	Major facilitator Superfamily
A7B19_RS46490	COG1028	Short-chain dehydrogenase reductase Sdr
A7B19_RS46495	COG0583	DNA-binding transcription factor activity
A7B19_RS46545	COG1609	Transcriptional regulator
A7B19_RS46550	COG0531	amino acid
A7B19_RS46555	COG0583	DNA-binding transcription factor activity
A7B19_RS46560	COG1982	Orn Lys Arg decarboxylase major
A7B19_RS46565	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A7B19_RS46575	COG0596	Alpha beta hydrolase
A7B19_RS46575	COG0508	dehydrogenase complex catalyzes the overall conversion of
A7B19_RS46600	COG2124	cytochrome p450
A7B19_RS46605	COG0583	DNA-binding transcription factor activity
A7B19_RS46665	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A7B19_RS46710	COG0270	DNA (cytosine-5-)-methyltransferase activity