locus-tag	class	description
CCZ36_RS00065	COG0210	DNA helicase
CCZ36_RS00260	COG3795	YCII-related domain
CCZ36_RS00265	COG4941	Belongs to the sigma-70 factor family
CCZ36_RS00360	COG1064	alcohol dehydrogenase
CCZ36_RS00425	COG2318	DinB family
CCZ36_RS00495	COG1349	DNA-binding transcription factor activity
CCZ36_RS00510	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CCZ36_RS00565	COG2318	DinB family
CCZ36_RS00670	COG0318	PFAM AMP-dependent synthetase and ligase
CCZ36_RS00735	COG2813	Specifically methylates the guanine in position
CCZ36_RS00800	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CCZ36_RS00805	COG2080	2 iron, 2 sulfur cluster binding
CCZ36_RS00855	COG2365	Tyrosine phosphatase family
CCZ36_RS00915	COG0148	phosphopyruvate hydratase activity
CCZ36_RS00925	COG2382	esterase
CCZ36_RS00940	COG1132	(ABC) transporter
CCZ36_RS00945	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CCZ36_RS00950	COG1120	ATPase activity
CCZ36_RS00955	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CCZ36_RS00980	COG0745	RESPONSE REGULATOR receiver
CCZ36_RS01015	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CCZ36_RS01095	COG1295	ribonuclease BN
CCZ36_RS01155	COG1028	Short-chain dehydrogenase reductase Sdr
CCZ36_RS01170	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CCZ36_RS01185	COG0300	oxidoreductase activity
CCZ36_RS01200	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CCZ36_RS01200	COG0723	plastoquinol--plastocyanin reductase activity
CCZ36_RS01215	COG1028	Short-chain dehydrogenase reductase Sdr
CCZ36_RS01270	COG0640	Transcriptional regulator
CCZ36_RS01280	COG1461	Dihydroxyacetone kinase
CCZ36_RS01295	COG0488	(ABC) transporter
CCZ36_RS01325	COG1191	sigma factor activity
CCZ36_RS01330	COG1309	transcriptional regulator
CCZ36_RS01340	COG1250	3-hydroxyacyl-CoA dehydrogenase
CCZ36_RS01345	COG1250	3-hydroxyacyl-CoA dehydrogenase
CCZ36_RS01345	COG0824	Thioesterase
CCZ36_RS01375	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CCZ36_RS01450	COG2837	iron assimilation
CCZ36_RS01520	COG1716	ATPase activity
CCZ36_RS01520	COG1131	(ABC) transporter
CCZ36_RS01520	COG0842	Transport permease protein
CCZ36_RS01530	COG2815	serine threonine protein kinase
CCZ36_RS01530	COG0515	serine threonine protein kinase
CCZ36_RS01610	COG0142	geranyltranstransferase activity
CCZ36_RS01725	COG0464	growth
CCZ36_RS01750	COG0702	epimerase
CCZ36_RS01780	COG1940	carbohydrate kinase activity
CCZ36_RS01785	COG2223	nitrite transmembrane transporter activity
CCZ36_RS01795	COG2197	response regulator
CCZ36_RS01800	COG4585	Histidine kinase
CCZ36_RS01815	COG0445	tRNA wobble uridine modification
CCZ36_RS01830	COG1660	Displays ATPase and GTPase activities
CCZ36_RS01865	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CCZ36_RS01910	COG0584	glycerophosphoryl diester phosphodiesterase
CCZ36_RS01930	COG0671	phosphoesterase, PA-phosphatase related
CCZ36_RS01975	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CCZ36_RS02045	COG1253	flavin adenine dinucleotide binding
CCZ36_RS02085	COG0531	amino acid
CCZ36_RS02095	COG0174	glutamine synthetase
CCZ36_RS02150	COG2835	tetraacyldisaccharide 4'-kinase activity
CCZ36_RS02165	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CCZ36_RS02215	COG1028	Short-chain dehydrogenase reductase Sdr
CCZ36_RS02220	COG1982	Orn Lys Arg decarboxylase major
CCZ36_RS02285	COG2890	protein-(glutamine-N5) methyltransferase activity
CCZ36_RS02315	COG2080	2 iron, 2 sulfur cluster binding
CCZ36_RS02330	COG0596	Alpha beta hydrolase
CCZ36_RS02350	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CCZ36_RS02365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CCZ36_RS02375	COG4592	Periplasmic binding protein
CCZ36_RS02425	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CCZ36_RS02450	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CCZ36_RS02460	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CCZ36_RS02520	COG4842	Belongs to the WXG100 family
CCZ36_RS02545	COG1404	Belongs to the peptidase S8 family
CCZ36_RS02580	COG0596	Alpha beta hydrolase
CCZ36_RS02605	COG1129	ABC transporter
CCZ36_RS02620	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CCZ36_RS02640	COG3940	Belongs to the glycosyl hydrolase 43 family
CCZ36_RS02650	COG2160	L-arabinose isomerase activity
CCZ36_RS02660	COG1609	Transcriptional regulator
CCZ36_RS02665	COG1879	ABC-type sugar transport system periplasmic component
CCZ36_RS02675	COG1172	Belongs to the binding-protein-dependent transport system permease family
CCZ36_RS02680	COG1172	Belongs to the binding-protein-dependent transport system permease family
CCZ36_RS02705	COG0523	cobalamin synthesis protein
CCZ36_RS02710	COG1501	Belongs to the glycosyl hydrolase 31 family
CCZ36_RS02725	COG4209	transmembrane transport
CCZ36_RS02730	COG0395	ABC-type sugar transport system, permease component
CCZ36_RS02800	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CCZ36_RS02810	COG1132	(ABC) transporter
CCZ36_RS02815	COG1846	Transcriptional regulator
CCZ36_RS02820	COG0277	FAD linked oxidase domain protein
CCZ36_RS02830	COG1132	(ABC) transporter
CCZ36_RS02835	COG1132	(ABC) transporter
CCZ36_RS02850	COG1252	NADH dehydrogenase
CCZ36_RS02855	COG1793	dna ligase
CCZ36_RS02870	COG1946	Acyl-CoA thioesterase
CCZ36_RS02905	COG0386	Belongs to the glutathione peroxidase family
CCZ36_RS02920	COG0242	peptide deformylase activity
CCZ36_RS02930	COG3442	glutamine amidotransferase
CCZ36_RS02935	COG0205	6-phosphofructokinase activity
CCZ36_RS02945	COG0204	Acyl-transferase
CCZ36_RS02960	COG0829	nickel cation binding
CCZ36_RS02965	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CCZ36_RS02980	COG0832	Belongs to the urease beta subunit family
CCZ36_RS02985	COG0831	urea catabolic process
CCZ36_RS03005	COG0740	serine-type endopeptidase activity
CCZ36_RS03020	COG1280	lysine exporter protein (LysE YggA)
CCZ36_RS03025	COG0583	DNA-binding transcription factor activity
CCZ36_RS03045	COG0156	8-amino-7-oxononanoate synthase activity
CCZ36_RS03050	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CCZ36_RS03055	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CCZ36_RS03060	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CCZ36_RS03065	COG2226	methyltransferase
CCZ36_RS03070	COG0456	acetyltransferase
CCZ36_RS03090	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CCZ36_RS03100	COG1940	carbohydrate kinase activity
CCZ36_RS03105	COG2188	Transcriptional regulator
CCZ36_RS03125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CCZ36_RS03140	COG0626	cystathionine gamma-synthase activity
CCZ36_RS03165	COG1522	sequence-specific DNA binding
CCZ36_RS03170	COG0419	ATPase involved in DNA repair
CCZ36_RS03175	COG0420	3'-5' exonuclease activity
CCZ36_RS03180	COG1739	Uncharacterized protein family UPF0029
CCZ36_RS03185	COG1832	CoA-binding protein
CCZ36_RS03230	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CCZ36_RS03245	COG1968	undecaprenyl-diphosphatase activity
CCZ36_RS03255	COG0243	molybdopterin cofactor binding
CCZ36_RS03305	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CCZ36_RS03315	COG2318	DinB family
CCZ36_RS03330	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CCZ36_RS03370	COG2175	clavaminate synthase activity
CCZ36_RS03380	COG0302	gtp cyclohydrolase
CCZ36_RS03385	COG0602	queuosine metabolic process
CCZ36_RS03395	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CCZ36_RS03400	COG0151	Belongs to the GarS family
CCZ36_RS03460	COG0583	DNA-binding transcription factor activity
CCZ36_RS03465	COG0697	spore germination
CCZ36_RS03520	COG0384	phenazine biosynthesis protein PhzF
CCZ36_RS03550	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CCZ36_RS03550	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CCZ36_RS03560	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CCZ36_RS03580	COG1716	ATPase activity
CCZ36_RS03605	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CCZ36_RS03640	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CCZ36_RS03650	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CCZ36_RS03690	COG2018	Roadblock/LC7 domain
CCZ36_RS03760	COG2364	Membrane
CCZ36_RS03770	COG2270	Major facilitator Superfamily
CCZ36_RS03785	COG1216	Glycosyl transferase, family 2
CCZ36_RS03810	COG1960	acyl-CoA dehydrogenase activity
CCZ36_RS03825	COG2318	DinB family
CCZ36_RS03870	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CCZ36_RS03875	COG0140	phosphoribosyl-ATP diphosphatase activity
CCZ36_RS03880	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CCZ36_RS03885	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CCZ36_RS03885	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CCZ36_RS03890	COG3201	nicotinamide mononucleotide transporter
CCZ36_RS03920	COG2233	PERMEase
CCZ36_RS03940	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CCZ36_RS03950	COG1012	belongs to the aldehyde dehydrogenase family
CCZ36_RS03965	COG2390	Transcriptional regulator
CCZ36_RS03970	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CCZ36_RS03980	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CCZ36_RS03995	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CCZ36_RS04005	COG1758	RNA polymerase activity
CCZ36_RS04020	COG0284	orotidine-5'-phosphate decarboxylase activity
CCZ36_RS04025	COG0167	dihydroorotate dehydrogenase activity
CCZ36_RS04030	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CCZ36_RS04035	COG0505	Belongs to the CarA family
CCZ36_RS04045	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CCZ36_RS04050	COG0540	Belongs to the ATCase OTCase family
CCZ36_RS04055	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CCZ36_RS04065	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CCZ36_RS04070	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CCZ36_RS04075	COG0006	proline dipeptidase activity
CCZ36_RS04085	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CCZ36_RS04090	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CCZ36_RS04095	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CCZ36_RS04100	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CCZ36_RS04110	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CCZ36_RS04115	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CCZ36_RS04135	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CCZ36_RS04165	COG4585	Histidine kinase
CCZ36_RS04170	COG2197	response regulator
CCZ36_RS04175	COG0124	histidyl-tRNA synthetase
CCZ36_RS04190	COG1196	nuclear chromosome segregation
CCZ36_RS04200	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CCZ36_RS04210	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CCZ36_RS04215	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CCZ36_RS04220	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CCZ36_RS04230	COG2255	four-way junction helicase activity
CCZ36_RS04235	COG0632	four-way junction helicase activity
CCZ36_RS04240	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CCZ36_RS04245	COG0217	transcriptional regulatory protein
CCZ36_RS04250	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CCZ36_RS04265	COG0438	transferase activity, transferring glycosyl groups
CCZ36_RS04275	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CCZ36_RS04300	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CCZ36_RS04315	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CCZ36_RS04360	COG0456	acetyltransferase
CCZ36_RS04370	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CCZ36_RS04425	COG1648	precorrin-2 dehydrogenase activity
CCZ36_RS04425	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CCZ36_RS04445	COG1464	Belongs to the NlpA lipoprotein family
CCZ36_RS04450	COG2011	ABC-type metal ion transport system permease component
CCZ36_RS04490	COG0477	Major facilitator Superfamily
CCZ36_RS04500	COG3973	AAA domain
CCZ36_RS04510	COG0165	Argininosuccinate lyase
CCZ36_RS04515	COG0137	argininosuccinate synthase activity
CCZ36_RS04525	COG1438	arginine binding
CCZ36_RS04530	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CCZ36_RS04535	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CCZ36_RS04540	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CCZ36_RS04545	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CCZ36_RS04550	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CCZ36_RS04560	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CCZ36_RS04575	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CCZ36_RS04625	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CCZ36_RS04635	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CCZ36_RS04675	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CCZ36_RS04690	COG0697	spore germination
CCZ36_RS04700	COG1649	PFAM Uncharacterised BCR, COG1649
CCZ36_RS04710	COG0789	Transcriptional regulator
CCZ36_RS04715	COG1725	Transcriptional regulator
CCZ36_RS04720	COG1131	(ABC) transporter
CCZ36_RS04750	COG0072	phenylalanine-tRNA ligase activity
CCZ36_RS04750	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CCZ36_RS04760	COG5002	protein histidine kinase activity
CCZ36_RS04765	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CCZ36_RS04770	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CCZ36_RS04775	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CCZ36_RS04780	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CCZ36_RS04790	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CCZ36_RS04800	COG1404	Belongs to the peptidase S8 family
CCZ36_RS04850	COG0517	IMP dehydrogenase activity
CCZ36_RS04850	COG4175	Glycine betaine
CCZ36_RS04855	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CCZ36_RS04900	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CCZ36_RS04945	COG0805	protein transport
CCZ36_RS04950	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CCZ36_RS04970	COG2378	regulation of single-species biofilm formation
CCZ36_RS04980	COG0545	Peptidyl-prolyl cis-trans isomerase
CCZ36_RS04985	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CCZ36_RS04995	COG1609	Transcriptional regulator
CCZ36_RS05000	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CCZ36_RS05005	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CCZ36_RS05020	COG4122	O-methyltransferase activity
CCZ36_RS05025	COG1222	aaa ATPase
CCZ36_RS05050	COG0517	IMP dehydrogenase activity
CCZ36_RS05050	COG1994	Peptidase M50
CCZ36_RS05060	COG2197	response regulator
CCZ36_RS05065	COG4166	transmembrane transport
CCZ36_RS05070	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CCZ36_RS05075	COG0646	methionine synthase
CCZ36_RS05075	COG1410	methionine synthase
CCZ36_RS05080	COG1414	Transcriptional regulator
CCZ36_RS05085	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CCZ36_RS05090	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CCZ36_RS05130	COG0598	Magnesium transport protein CorA
CCZ36_RS05140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CCZ36_RS05145	COG0667	Aldo Keto reductase
CCZ36_RS05175	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CCZ36_RS05185	COG0564	pseudouridine synthase activity
CCZ36_RS05190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CCZ36_RS05200	COG2186	Transcriptional regulator
CCZ36_RS05205	COG3265	gluconokinase activity
CCZ36_RS05230	COG3573	Dehydrogenase
CCZ36_RS05235	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CCZ36_RS05240	COG2149	membrane
CCZ36_RS05260	COG1960	acyl-CoA dehydrogenase activity
CCZ36_RS05275	COG0318	PFAM AMP-dependent synthetase and ligase
CCZ36_RS05285	COG3876	Protein conserved in bacteria
CCZ36_RS05300	COG0789	Transcriptional regulator
CCZ36_RS05320	COG1960	acyl-CoA dehydrogenase activity
CCZ36_RS05330	COG0640	Transcriptional regulator
CCZ36_RS05360	COG2851	Citrate transporter
CCZ36_RS05365	COG0243	molybdopterin cofactor binding
CCZ36_RS05370	COG1309	transcriptional regulator
CCZ36_RS05375	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CCZ36_RS05380	COG2188	Transcriptional regulator
CCZ36_RS05390	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CCZ36_RS05400	COG2755	lipolytic protein G-D-S-L family
CCZ36_RS05410	COG1725	Transcriptional regulator
CCZ36_RS05430	COG0346	lactoylglutathione lyase activity
CCZ36_RS05490	COG0641	radical SAM
CCZ36_RS05525	COG1799	cell septum assembly
CCZ36_RS05530	COG1960	acyl-CoA dehydrogenase activity
CCZ36_RS05535	COG0477	Major facilitator Superfamily
CCZ36_RS05540	COG0671	phosphoesterase, PA-phosphatase related
CCZ36_RS05560	COG0438	transferase activity, transferring glycosyl groups
CCZ36_RS05575	COG1160	GTP binding
CCZ36_RS05585	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CCZ36_RS05620	COG0494	nUDIX hydrolase
CCZ36_RS05640	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CCZ36_RS05645	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CCZ36_RS05660	COG0686	Belongs to the AlaDH PNT family
CCZ36_RS05670	COG0494	nUDIX hydrolase
CCZ36_RS05675	COG0504	CTP synthase activity
CCZ36_RS05680	COG3387	PFAM Glycoside hydrolase 15-related
CCZ36_RS05690	COG0789	Transcriptional regulator
CCZ36_RS05705	COG0497	DNA recombination
CCZ36_RS05710	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CCZ36_RS05730	COG1120	ATPase activity
CCZ36_RS05735	COG0647	UMP catabolic process
CCZ36_RS05805	COG1119	ATPase activity
CCZ36_RS05820	COG2197	response regulator
CCZ36_RS05845	COG0842	Transport permease protein
CCZ36_RS05845	COG1131	(ABC) transporter
CCZ36_RS05845	COG1716	ATPase activity
CCZ36_RS05850	COG0560	Phosphoserine phosphatase
CCZ36_RS05850	COG3830	Belongs to the UPF0237 family
CCZ36_RS05870	COG2186	Transcriptional regulator
CCZ36_RS05880	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CCZ36_RS05885	COG1028	Short-chain dehydrogenase reductase Sdr
CCZ36_RS05900	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CCZ36_RS05910	COG2261	transglycosylase associated protein
CCZ36_RS05925	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CCZ36_RS05930	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CCZ36_RS05945	COG1404	Belongs to the peptidase S8 family
CCZ36_RS05965	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CCZ36_RS05965	COG1199	ATP-dependent helicase activity
CCZ36_RS05980	COG3387	PFAM Glycoside hydrolase 15-related
CCZ36_RS06030	COG0488	(ABC) transporter
CCZ36_RS06055	COG0235	Class ii aldolase
CCZ36_RS06070	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CCZ36_RS06075	COG1492	cobalamin metabolic process
CCZ36_RS06090	COG1797	cobyrinic acid a,c-diamide synthase activity
CCZ36_RS06120	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CCZ36_RS06150	COG1902	pentaerythritol trinitrate reductase activity
CCZ36_RS06155	COG1846	Transcriptional regulator
CCZ36_RS06185	COG1414	Transcriptional regulator
CCZ36_RS06200	COG4585	Histidine kinase
CCZ36_RS06205	COG2197	response regulator
CCZ36_RS06210	COG0768	penicillin binding
CCZ36_RS06255	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CCZ36_RS06260	COG2171	N-acyltransferase activity
CCZ36_RS06275	COG3226	Transcriptional regulator
CCZ36_RS06290	COG2151	metal-sulfur cluster biosynthetic enzyme
CCZ36_RS06295	COG0822	iron-sulfur transferase activity
CCZ36_RS06300	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CCZ36_RS06305	COG0396	ATPase activity
CCZ36_RS06315	COG0719	Fe-S assembly protein
CCZ36_RS06355	COG0109	protoheme IX farnesyltransferase activity
CCZ36_RS06365	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CCZ36_RS06380	COG0363	glucosamine-6-phosphate deaminase activity
CCZ36_RS06405	COG0166	Belongs to the GPI family
CCZ36_RS06415	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CCZ36_RS06420	COG0149	triose-phosphate isomerase activity
CCZ36_RS06425	COG0126	phosphoglycerate kinase activity
CCZ36_RS06430	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CCZ36_RS06435	COG1481	regulation of sporulation
CCZ36_RS06440	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CCZ36_RS06445	COG1660	Displays ATPase and GTPase activities
CCZ36_RS06450	COG0322	excinuclease ABC activity
CCZ36_RS06475	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CCZ36_RS06505	COG0556	nucleotide-excision repair
CCZ36_RS06515	COG0584	glycerophosphoryl diester phosphodiesterase
CCZ36_RS06525	COG2814	Major facilitator Superfamily
CCZ36_RS06540	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CCZ36_RS06555	COG0436	Aminotransferase
CCZ36_RS06580	COG2226	methyltransferase
CCZ36_RS06590	COG4249	Peptidase C14 caspase catalytic subunit p20
CCZ36_RS06590	COG2319	Wd-40 repeat
CCZ36_RS06615	COG0237	dephospho-CoA kinase activity
CCZ36_RS06635	COG2226	methyltransferase
CCZ36_RS06670	COG2050	protein possibly involved in aromatic compounds catabolism
CCZ36_RS06685	COG3903	Transcriptional regulator
CCZ36_RS06685	COG3629	intracellular signal transduction
CCZ36_RS06690	COG1132	(ABC) transporter
CCZ36_RS06795	COG0287	Prephenate dehydrogenase
CCZ36_RS06795	COG1605	Chorismate mutase
CCZ36_RS06840	COG1278	Cold shock
CCZ36_RS06845	COG0183	Belongs to the thiolase family
CCZ36_RS06850	COG1309	transcriptional regulator
CCZ36_RS06875	COG0705	Rhomboid family
CCZ36_RS06885	COG0067	glutamate synthase
CCZ36_RS06885	COG0069	glutamate synthase activity
CCZ36_RS06885	COG0070	glutamate synthase
CCZ36_RS06915	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CCZ36_RS06920	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CCZ36_RS06930	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CCZ36_RS06940	COG0159	tryptophan synthase activity
CCZ36_RS06945	COG0133	tryptophan synthase activity
CCZ36_RS06955	COG0134	indole-3-glycerol-phosphate synthase activity
CCZ36_RS06975	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CCZ36_RS06980	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CCZ36_RS07000	COG2508	Transcriptional regulator
CCZ36_RS07015	COG0107	imidazoleglycerol-phosphate synthase activity
CCZ36_RS07020	COG0251	oxidation-reduction process
CCZ36_RS07025	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CCZ36_RS07035	COG0131	Imidazoleglycerol-phosphate dehydratase
CCZ36_RS07040	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CCZ36_RS07045	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CCZ36_RS07085	COG1432	Conserved Protein
CCZ36_RS07095	COG0587	DNA-directed DNA polymerase activity
CCZ36_RS07140	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CCZ36_RS07150	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CCZ36_RS07155	COG3599	regulation of cell shape
CCZ36_RS07165	COG1799	cell septum assembly
CCZ36_RS07170	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CCZ36_RS07190	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CCZ36_RS07200	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CCZ36_RS07205	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CCZ36_RS07215	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CCZ36_RS07230	COG0275	rRNA processing
CCZ36_RS07240	COG0714	Associated with various cellular activities
CCZ36_RS07260	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CCZ36_RS07290	COG1233	COG1233 Phytoene dehydrogenase and related
CCZ36_RS07305	COG0352	thiamine-phosphate diphosphorylase activity
CCZ36_RS07325	COG2022	thiamine diphosphate biosynthetic process
CCZ36_RS07325	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CCZ36_RS07335	COG2022	thiamine diphosphate biosynthetic process
CCZ36_RS07340	COG2815	serine threonine protein kinase
CCZ36_RS07340	COG0515	serine threonine protein kinase
CCZ36_RS07345	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CCZ36_RS07350	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CCZ36_RS07355	COG2193	ferroxidase activity
CCZ36_RS07365	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CCZ36_RS07380	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CCZ36_RS07385	COG2197	response regulator
CCZ36_RS07415	COG1940	carbohydrate kinase activity
CCZ36_RS07425	COG0003	Pfam Anion-transporting ATPase
CCZ36_RS07445	COG0438	transferase activity, transferring glycosyl groups
CCZ36_RS07490	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CCZ36_RS07495	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CCZ36_RS07500	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CCZ36_RS07505	COG0723	plastoquinol--plastocyanin reductase activity
CCZ36_RS07510	COG2010	Cytochrome c
CCZ36_RS07515	COG1845	cytochrome c oxidase, subunit III
CCZ36_RS07525	COG1376	ErfK ybiS ycfS ynhG family protein
CCZ36_RS07535	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CCZ36_RS07545	COG1104	cysteine desulfurase activity
CCZ36_RS07550	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CCZ36_RS07570	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CCZ36_RS07580	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CCZ36_RS07585	COG2197	response regulator
CCZ36_RS07590	COG4585	Histidine kinase
CCZ36_RS07610	COG4106	trans-aconitate 2-methyltransferase activity
CCZ36_RS07615	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CCZ36_RS07630	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CCZ36_RS07645	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CCZ36_RS07650	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CCZ36_RS07655	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CCZ36_RS07660	COG0508	dehydrogenase complex catalyzes the overall conversion of
CCZ36_RS07670	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CCZ36_RS07690	COG1090	epimerase
CCZ36_RS07705	COG0321	lipoyl(octanoyl) transferase activity
CCZ36_RS07710	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CCZ36_RS07740	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CCZ36_RS07745	COG3896	Chloramphenicol phosphotransferase-like protein
CCZ36_RS07755	COG1846	Transcriptional regulator
CCZ36_RS07760	COG2362	D-Aminopeptidase
CCZ36_RS07785	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CCZ36_RS07790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CCZ36_RS07815	COG0745	RESPONSE REGULATOR receiver
CCZ36_RS07825	COG2197	response regulator
CCZ36_RS07895	COG0366	Alpha amylase catalytic
CCZ36_RS07900	COG0395	ABC-type sugar transport system, permease component
CCZ36_RS07910	COG2182	Extracellular solute-binding protein
CCZ36_RS07915	COG1609	Transcriptional regulator
CCZ36_RS07925	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CCZ36_RS07935	COG2890	protein-(glutamine-N5) methyltransferase activity
CCZ36_RS07975	COG0174	glutamine synthetase
CCZ36_RS08000	COG2132	Multicopper oxidase
CCZ36_RS08005	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CCZ36_RS08005	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CCZ36_RS08010	COG2814	Major facilitator Superfamily
CCZ36_RS08025	COG0477	Major facilitator Superfamily
CCZ36_RS08030	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CCZ36_RS08050	COG1994	Peptidase M50
CCZ36_RS08115	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CCZ36_RS08120	COG1120	ATPase activity
CCZ36_RS08140	COG1834	amidinotransferase
CCZ36_RS08155	COG2814	Major facilitator Superfamily
CCZ36_RS08170	COG1028	Short-chain dehydrogenase reductase Sdr
CCZ36_RS08180	COG0384	phenazine biosynthesis protein PhzF
CCZ36_RS08220	COG4948	Mandelate Racemase Muconate Lactonizing
CCZ36_RS08225	COG2273	Hydrolase Family 16
CCZ36_RS08250	COG0557	exoribonuclease II activity
CCZ36_RS08255	COG3022	response to hydroperoxide
CCZ36_RS08260	COG0800	Aldolase
CCZ36_RS08275	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CCZ36_RS08280	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CCZ36_RS08300	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CCZ36_RS08310	COG2814	Major facilitator Superfamily
CCZ36_RS08355	COG0438	transferase activity, transferring glycosyl groups
CCZ36_RS08360	COG1309	transcriptional regulator
CCZ36_RS08425	COG3845	ABC transporter
CCZ36_RS08435	COG3415	Transposase
CCZ36_RS08435	COG2801	Transposase and inactivated derivatives
CCZ36_RS08530	COG0483	inositol monophosphate 1-phosphatase activity
CCZ36_RS08560	COG0582	viral genome integration into host DNA
CCZ36_RS08595	COG1358	cellular component organization or biogenesis
CCZ36_RS08645	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CCZ36_RS08655	COG0477	Major facilitator Superfamily
CCZ36_RS08660	COG1309	transcriptional regulator
CCZ36_RS08675	COG4585	Histidine kinase
CCZ36_RS08680	COG2197	response regulator
CCZ36_RS08695	COG3409	Peptidoglycan-binding domain 1 protein
CCZ36_RS08715	COG0667	Aldo Keto reductase
CCZ36_RS08720	COG0789	Transcriptional regulator
CCZ36_RS08730	COG2205	protein histidine kinase activity
CCZ36_RS08735	COG0745	RESPONSE REGULATOR receiver
CCZ36_RS08745	COG1929	Belongs to the glycerate kinase type-1 family
CCZ36_RS08770	COG1741	Belongs to the pirin family
CCZ36_RS08785	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CCZ36_RS08790	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CCZ36_RS08795	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CCZ36_RS08815	COG1280	lysine exporter protein (LysE YggA)
CCZ36_RS08825	COG1764	response to oxidative stress
CCZ36_RS08830	COG2130	NADP-dependent
CCZ36_RS08860	COG1522	sequence-specific DNA binding
CCZ36_RS08875	COG0318	PFAM AMP-dependent synthetase and ligase
CCZ36_RS08880	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CCZ36_RS08880	COG0825	malonyl-CoA metabolic process
CCZ36_RS08885	COG1309	transcriptional regulator
CCZ36_RS08890	COG1028	Short-chain dehydrogenase reductase Sdr
CCZ36_RS08895	COG0477	Major facilitator Superfamily
CCZ36_RS08920	COG0586	Pfam SNARE associated Golgi protein
CCZ36_RS08945	COG1316	TRANSCRIPTIONal
CCZ36_RS08970	COG2175	clavaminate synthase activity
CCZ36_RS08985	COG0831	urea catabolic process
CCZ36_RS08985	COG0832	Belongs to the urease beta subunit family
CCZ36_RS08990	COG0804	urea catabolic process
CCZ36_RS09000	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CCZ36_RS09005	COG0829	nickel cation binding
CCZ36_RS09015	COG2072	flavoprotein involved in K transport
CCZ36_RS09050	COG1070	Carbohydrate kinase
CCZ36_RS09065	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CCZ36_RS09070	COG0358	DNA primase activity
CCZ36_RS09080	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CCZ36_RS09090	COG2949	membrane
CCZ36_RS09255	COG0574	Belongs to the PEP-utilizing enzyme family
CCZ36_RS09255	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CCZ36_RS09265	COG3842	ATPase activity
CCZ36_RS09285	COG2188	Transcriptional regulator
CCZ36_RS09305	COG2066	Belongs to the glutaminase family
CCZ36_RS09320	COG3848	Pyruvate phosphate dikinase
CCZ36_RS09320	COG0574	Belongs to the PEP-utilizing enzyme family
CCZ36_RS09415	COG1595	DNA-templated transcription, initiation
CCZ36_RS09435	COG0423	glycine-tRNA ligase activity
CCZ36_RS09445	COG1121	(ABC) transporter
CCZ36_RS09450	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CCZ36_RS09460	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CCZ36_RS09465	COG1381	Involved in DNA repair and RecF pathway recombination
CCZ36_RS09475	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CCZ36_RS09490	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CCZ36_RS09500	COG2315	Protein conserved in bacteria
CCZ36_RS09510	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CCZ36_RS09520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CCZ36_RS09530	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CCZ36_RS09535	COG1234	tRNA 3'-trailer cleavage
CCZ36_RS09540	COG0537	adenosine 5'-monophosphoramidase activity
CCZ36_RS09555	COG0484	heat shock protein binding
CCZ36_RS09560	COG1420	regulation of RNA biosynthetic process
CCZ36_RS09600	COG1022	Amp-dependent synthetase and ligase
CCZ36_RS09605	COG0481	GTPase activity
CCZ36_RS09610	COG0268	Binds directly to 16S ribosomal RNA
CCZ36_RS09640	COG1555	photosystem II stabilization
CCZ36_RS09645	COG1307	EDD domain protein, DegV family
CCZ36_RS09655	COG0495	leucyl-tRNA aminoacylation
CCZ36_RS09665	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CCZ36_RS09690	COG0588	phosphoglycerate mutase activity
CCZ36_RS09695	COG0799	negative regulation of ribosome biogenesis
CCZ36_RS09710	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CCZ36_RS09715	COG0501	Belongs to the peptidase M48B family
CCZ36_RS09730	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CCZ36_RS09740	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CCZ36_RS09745	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CCZ36_RS09765	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CCZ36_RS09770	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CCZ36_RS09775	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CCZ36_RS09805	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CCZ36_RS09810	COG1530	ribonuclease E activity
CCZ36_RS09835	COG0772	Belongs to the SEDS family
CCZ36_RS09840	COG0768	penicillin binding
CCZ36_RS09855	COG1077	Cell shape determining protein MreB Mrl
CCZ36_RS09860	COG0105	UTP biosynthetic process
CCZ36_RS09870	COG0285	dihydrofolate synthase activity
CCZ36_RS09875	COG0525	valine-tRNA ligase activity
CCZ36_RS09885	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CCZ36_RS09890	COG0740	serine-type endopeptidase activity
CCZ36_RS09895	COG0740	serine-type endopeptidase activity
CCZ36_RS09900	COG0544	peptidyl-prolyl cis-trans isomerase activity
CCZ36_RS09920	COG3594	Acyltransferase
CCZ36_RS09930	COG0475	glutathione-regulated potassium exporter activity
CCZ36_RS09950	COG1113	amino acid transport
CCZ36_RS09960	COG1268	BioY protein
CCZ36_RS09965	COG1113	amino acid transport
CCZ36_RS09970	COG1113	amino acid transport
CCZ36_RS09975	COG0584	glycerophosphoryl diester phosphodiesterase
CCZ36_RS09985	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CCZ36_RS09990	COG0640	Transcriptional regulator
CCZ36_RS10000	COG0110	maltose O-acetyltransferase activity
CCZ36_RS10010	COG2252	PERMEase
CCZ36_RS10025	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CCZ36_RS10065	COG4266	Belongs to the allantoicase family
CCZ36_RS10090	COG3291	Pkd domain containing protein
CCZ36_RS10090	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CCZ36_RS10100	COG0668	transmembrane transport
CCZ36_RS10105	COG1940	carbohydrate kinase activity
CCZ36_RS10115	COG1175	transmembrane transport
CCZ36_RS10120	COG0395	ABC-type sugar transport system, permease component
CCZ36_RS10125	COG1486	melibiose metabolic process
CCZ36_RS10140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CCZ36_RS10170	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CCZ36_RS10175	COG2346	COG2346, Truncated hemoglobins
CCZ36_RS10190	COG1136	(ABC) transporter
CCZ36_RS10190	COG0577	efflux transmembrane transporter activity
CCZ36_RS10215	COG0629	single-stranded DNA binding
CCZ36_RS10245	COG2197	response regulator
CCZ36_RS10285	COG1131	(ABC) transporter
CCZ36_RS10305	COG4585	Histidine kinase
CCZ36_RS10320	COG3962	Belongs to the TPP enzyme family
CCZ36_RS10335	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CCZ36_RS10360	COG2409	Drug exporters of the RND superfamily
CCZ36_RS10385	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CCZ36_RS10405	COG2197	response regulator
CCZ36_RS10445	COG2318	DinB family
CCZ36_RS10460	COG0673	inositol 2-dehydrogenase activity
CCZ36_RS10465	COG1609	Transcriptional regulator
CCZ36_RS10490	COG0515	serine threonine protein kinase
CCZ36_RS10520	COG1404	Belongs to the peptidase S8 family
CCZ36_RS10540	COG0583	DNA-binding transcription factor activity
CCZ36_RS10545	COG1472	Belongs to the glycosyl hydrolase 3 family
CCZ36_RS10575	COG0028	Belongs to the TPP enzyme family
CCZ36_RS10615	COG0657	acetylesterase activity
CCZ36_RS10645	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CCZ36_RS10665	COG1946	Acyl-CoA thioesterase
CCZ36_RS10700	COG1309	transcriptional regulator
CCZ36_RS10705	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CCZ36_RS10720	COG1960	acyl-CoA dehydrogenase activity
CCZ36_RS10740	COG1733	regulation of RNA biosynthetic process
CCZ36_RS10755	COG0076	glutamate decarboxylase activity
CCZ36_RS10760	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CCZ36_RS10785	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CCZ36_RS10795	COG4977	sequence-specific DNA binding
CCZ36_RS10815	COG0519	Catalyzes the synthesis of GMP from XMP
CCZ36_RS10875	COG1028	Short-chain dehydrogenase reductase Sdr
CCZ36_RS10880	COG1028	Short-chain dehydrogenase reductase Sdr
CCZ36_RS10885	COG3903	Transcriptional regulator
CCZ36_RS10885	COG3629	intracellular signal transduction
CCZ36_RS10910	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CCZ36_RS10915	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CCZ36_RS10925	COG1595	DNA-templated transcription, initiation
CCZ36_RS10930	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CCZ36_RS10935	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CCZ36_RS10950	COG0395	ABC-type sugar transport system, permease component
CCZ36_RS11005	COG0406	alpha-ribazole phosphatase activity
CCZ36_RS11055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CCZ36_RS11075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CCZ36_RS11080	COG0765	amino acid transport
CCZ36_RS11085	COG0765	amino acid transport
CCZ36_RS11090	COG1126	abc transporter atp-binding protein
CCZ36_RS11115	COG3397	chitin binding
CCZ36_RS11185	COG3842	ATPase activity
CCZ36_RS11195	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CCZ36_RS11210	COG1940	carbohydrate kinase activity
CCZ36_RS11215	COG0673	inositol 2-dehydrogenase activity
CCZ36_RS11220	COG4702	Belongs to the UPF0303 family
CCZ36_RS11230	COG4455	Protein of avirulence locus involved in temperature-dependent protein secretion
CCZ36_RS11230	COG0706	membrane insertase activity
CCZ36_RS11250	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CCZ36_RS11380	COG2733	membrane
CCZ36_RS11395	COG4555	ABC transporter
CCZ36_RS11410	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CCZ36_RS11435	COG0477	Major facilitator Superfamily
CCZ36_RS11455	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CCZ36_RS11465	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CCZ36_RS11470	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CCZ36_RS11475	COG1263	PTS System
CCZ36_RS11480	COG1263	PTS System
CCZ36_RS11515	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CCZ36_RS11530	COG1113	amino acid transport
CCZ36_RS11540	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CCZ36_RS11550	COG1335	isochorismatase
CCZ36_RS11585	COG0277	FAD linked oxidase domain protein
CCZ36_RS11595	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CCZ36_RS11605	COG1174	glycine betaine transport
CCZ36_RS11615	COG1174	glycine betaine transport
CCZ36_RS11640	COG3480	Lon protease (S16) C-terminal proteolytic domain
CCZ36_RS11655	COG2814	Major facilitator Superfamily
CCZ36_RS11705	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CCZ36_RS11710	COG0395	ABC-type sugar transport system, permease component
CCZ36_RS11730	COG1678	Uncharacterized ACR, COG1678
CCZ36_RS11735	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CCZ36_RS11750	COG0776	regulation of translation
CCZ36_RS11760	COG3973	AAA domain
CCZ36_RS11760	COG3973	AAA domain
CCZ36_RS11790	COG2223	nitrite transmembrane transporter activity
CCZ36_RS11810	COG0583	DNA-binding transcription factor activity
CCZ36_RS11825	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CCZ36_RS11830	COG0793	Belongs to the peptidase S41A family
CCZ36_RS11835	COG2177	Part of the ABC transporter FtsEX involved in
CCZ36_RS11840	COG2884	Cell division ATP-binding protein ftsE
CCZ36_RS11855	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CCZ36_RS11860	COG0515	serine threonine protein kinase
CCZ36_RS11865	COG0515	serine threonine protein kinase
CCZ36_RS11875	COG1653	transport
CCZ36_RS11880	COG1175	transmembrane transport
CCZ36_RS11885	COG0395	ABC-type sugar transport system, permease component
CCZ36_RS11890	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CCZ36_RS11895	COG0438	transferase activity, transferring glycosyl groups
CCZ36_RS11900	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CCZ36_RS11905	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CCZ36_RS11910	COG4122	O-methyltransferase activity
CCZ36_RS11915	COG1073	alpha beta
CCZ36_RS11915	COG2226	methyltransferase
CCZ36_RS11920	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CCZ36_RS11925	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CCZ36_RS11935	COG1309	transcriptional regulator
CCZ36_RS11945	COG1134	teichoic acid transport
CCZ36_RS11950	COG2902	Dehydrogenase
CCZ36_RS11975	COG0653	protein targeting
CCZ36_RS11990	COG2197	response regulator
CCZ36_RS11995	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CCZ36_RS12010	COG0823	Involved in the tonB-independent uptake of proteins
CCZ36_RS12015	COG5000	phosphorelay sensor kinase activity
CCZ36_RS12015	COG5002	protein histidine kinase activity
CCZ36_RS12020	COG0745	RESPONSE REGULATOR receiver
CCZ36_RS12025	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CCZ36_RS12045	COG0714	Associated with various cellular activities
CCZ36_RS12090	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CCZ36_RS12110	COG2835	tetraacyldisaccharide 4'-kinase activity
CCZ36_RS12120	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CCZ36_RS12160	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CCZ36_RS12165	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
CCZ36_RS12165	COG0778	Nitroreductase
CCZ36_RS12175	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CCZ36_RS12190	COG1316	TRANSCRIPTIONal
CCZ36_RS12195	COG1316	TRANSCRIPTIONal
CCZ36_RS12220	COG1316	TRANSCRIPTIONal
CCZ36_RS12255	COG2226	methyltransferase
CCZ36_RS12365	COG2205	protein histidine kinase activity
CCZ36_RS12370	COG0745	RESPONSE REGULATOR receiver
CCZ36_RS12375	COG3104	oligopeptide transport
CCZ36_RS12390	COG1366	Belongs to the anti-sigma-factor antagonist family
CCZ36_RS12395	COG1191	sigma factor activity
CCZ36_RS12400	COG1228	amidohydrolase
CCZ36_RS12415	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CCZ36_RS12420	COG0531	amino acid
CCZ36_RS12465	COG1136	(ABC) transporter
CCZ36_RS12465	COG0577	efflux transmembrane transporter activity
CCZ36_RS12470	COG1136	(ABC) transporter
CCZ36_RS12470	COG0577	efflux transmembrane transporter activity
CCZ36_RS12475	COG3409	Peptidoglycan-binding domain 1 protein
CCZ36_RS12500	COG2755	lipolytic protein G-D-S-L family
CCZ36_RS12505	COG0183	Belongs to the thiolase family
CCZ36_RS12530	COG0577	efflux transmembrane transporter activity
CCZ36_RS12530	COG1136	(ABC) transporter
CCZ36_RS12535	COG1136	(ABC) transporter
CCZ36_RS12535	COG0577	efflux transmembrane transporter activity
CCZ36_RS12540	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CCZ36_RS12545	COG1252	NADH dehydrogenase
CCZ36_RS12565	COG0148	phosphopyruvate hydratase activity
CCZ36_RS12575	COG1652	LysM domain
CCZ36_RS12600	COG2815	serine threonine protein kinase
CCZ36_RS12600	COG0515	serine threonine protein kinase
CCZ36_RS12675	COG0577	efflux transmembrane transporter activity
CCZ36_RS12680	COG1136	(ABC) transporter
CCZ36_RS12685	COG0477	Major facilitator Superfamily
CCZ36_RS12690	COG0640	Transcriptional regulator
CCZ36_RS12695	COG0346	lactoylglutathione lyase activity
CCZ36_RS12740	COG2124	cytochrome p450
CCZ36_RS12745	COG2124	cytochrome p450
CCZ36_RS12755	COG0667	Aldo Keto reductase
CCZ36_RS12795	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CCZ36_RS12800	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CCZ36_RS12805	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CCZ36_RS12810	COG0193	aminoacyl-tRNA hydrolase activity
CCZ36_RS12820	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CCZ36_RS12845	COG4106	trans-aconitate 2-methyltransferase activity
CCZ36_RS12850	COG1846	Transcriptional regulator
CCZ36_RS12855	COG2197	response regulator
CCZ36_RS12865	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CCZ36_RS12880	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CCZ36_RS12910	COG0488	(ABC) transporter
CCZ36_RS12915	COG2197	response regulator
CCZ36_RS12920	COG4585	Histidine kinase
CCZ36_RS12940	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CCZ36_RS12945	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CCZ36_RS12955	COG0084	hydrolase, TatD family'
CCZ36_RS12980	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CCZ36_RS13010	COG2226	methyltransferase
CCZ36_RS13130	COG2223	nitrite transmembrane transporter activity
CCZ36_RS13140	COG0442	prolyl-tRNA aminoacylation
CCZ36_RS13175	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CCZ36_RS13190	COG1028	Short-chain dehydrogenase reductase Sdr
CCZ36_RS13195	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CCZ36_RS13210	COG2409	Drug exporters of the RND superfamily
CCZ36_RS13220	COG0793	Belongs to the peptidase S41A family
CCZ36_RS13220	COG4946	Tricorn protease homolog
CCZ36_RS13235	COG1028	Short-chain dehydrogenase reductase Sdr
CCZ36_RS13245	COG2072	flavoprotein involved in K transport
CCZ36_RS13255	COG0708	Exodeoxyribonuclease III
CCZ36_RS13295	COG1073	alpha beta
CCZ36_RS13300	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CCZ36_RS13305	COG1834	amidinotransferase
CCZ36_RS13320	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CCZ36_RS13330	COG0798	PFAM Bile acid sodium symporter
CCZ36_RS13335	COG0640	Transcriptional regulator
CCZ36_RS13355	COG0640	Transcriptional regulator
CCZ36_RS13370	COG1131	(ABC) transporter
CCZ36_RS13375	COG3559	Exporter of polyketide antibiotics
CCZ36_RS13405	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CCZ36_RS13410	COG0521	Mo-molybdopterin cofactor biosynthetic process
CCZ36_RS13415	COG0315	cyclic pyranopterin monophosphate synthase activity
CCZ36_RS13425	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CCZ36_RS13430	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CCZ36_RS13440	COG3263	regulation of cellular component size
CCZ36_RS13455	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CCZ36_RS13465	COG1970	mechanosensitive ion channel activity
CCZ36_RS13485	COG0437	4 iron, 4 sulfur cluster binding
CCZ36_RS13490	COG0243	molybdopterin cofactor binding
CCZ36_RS13510	COG0477	Major facilitator Superfamily
CCZ36_RS13525	COG3384	dioxygenase
CCZ36_RS13530	COG1846	Transcriptional regulator
CCZ36_RS13555	COG1115	amino acid carrier protein
CCZ36_RS13585	COG1686	Belongs to the peptidase S11 family
CCZ36_RS13640	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CCZ36_RS13655	COG0667	Aldo Keto reductase
CCZ36_RS13660	COG2226	methyltransferase
CCZ36_RS13670	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CCZ36_RS13705	COG0768	penicillin binding
CCZ36_RS13760	COG3866	Pectate lyase
CCZ36_RS13765	COG2755	lipolytic protein G-D-S-L family
CCZ36_RS13770	COG1653	transport
CCZ36_RS13790	COG0395	ABC-type sugar transport system, permease component
CCZ36_RS13805	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CCZ36_RS13810	COG1802	Transcriptional regulator
CCZ36_RS13815	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CCZ36_RS13825	COG0667	Aldo Keto reductase
CCZ36_RS13875	COG3940	Belongs to the glycosyl hydrolase 43 family
CCZ36_RS13915	COG1028	Short-chain dehydrogenase reductase Sdr
CCZ36_RS13935	COG1309	transcriptional regulator
CCZ36_RS13960	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CCZ36_RS13970	COG0163	prenyltransferase activity
CCZ36_RS13985	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CCZ36_RS13995	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CCZ36_RS14000	COG1333	cytochrome c biogenesis protein
CCZ36_RS14005	COG0785	Cytochrome C biogenesis protein
CCZ36_RS14010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CCZ36_RS14020	COG0406	alpha-ribazole phosphatase activity
CCZ36_RS14025	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CCZ36_RS14065	COG3842	ATPase activity
CCZ36_RS14070	COG1176	ABC-type spermidine putrescine transport system, permease component I
CCZ36_RS14085	COG2188	Transcriptional regulator
CCZ36_RS14100	COG1690	Belongs to the RtcB family
CCZ36_RS14120	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
CCZ36_RS14125	COG0018	arginyl-trna synthetase
CCZ36_RS14160	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CCZ36_RS14190	COG0113	porphobilinogen synthase activity
CCZ36_RS14195	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CCZ36_RS14195	COG1648	precorrin-2 dehydrogenase activity
CCZ36_RS14200	COG0181	hydroxymethylbilane synthase activity
CCZ36_RS14205	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CCZ36_RS14210	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CCZ36_RS14260	COG0123	including yeast histone deacetylase and acetoin utilization protein
CCZ36_RS14265	COG2223	nitrite transmembrane transporter activity
CCZ36_RS14270	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CCZ36_RS14295	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CCZ36_RS14315	COG4991	sh3 domain protein
CCZ36_RS14320	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CCZ36_RS14320	COG0515	serine threonine protein kinase
CCZ36_RS14325	COG0129	dihydroxy-acid dehydratase activity
CCZ36_RS14335	COG1082	Xylose isomerase domain protein TIM barrel
CCZ36_RS14340	COG0248	Ppx GppA phosphatase
CCZ36_RS14360	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
CCZ36_RS14370	COG1194	a g-specific adenine glycosylase
CCZ36_RS14375	COG1595	DNA-templated transcription, initiation
CCZ36_RS14385	COG0745	RESPONSE REGULATOR receiver
CCZ36_RS14390	COG2205	protein histidine kinase activity
CCZ36_RS14395	COG0739	heme binding
CCZ36_RS14430	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CCZ36_RS14450	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CCZ36_RS14460	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CCZ36_RS14465	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CCZ36_RS14505	COG0649	NAD binding
CCZ36_RS14515	COG1732	Glycine betaine
CCZ36_RS14520	COG1174	glycine betaine transport
CCZ36_RS14525	COG1174	glycine betaine transport
CCZ36_RS14530	COG0517	IMP dehydrogenase activity
CCZ36_RS14530	COG1125	glycine betaine transport
CCZ36_RS14540	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CCZ36_RS14540	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CCZ36_RS14560	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CCZ36_RS14570	COG0302	gtp cyclohydrolase
CCZ36_RS14585	COG0037	tRNA processing
CCZ36_RS14595	COG2027	D-alanyl-D-alanine carboxypeptidase
CCZ36_RS14600	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CCZ36_RS14625	COG0076	glutamate decarboxylase activity
CCZ36_RS14655	COG1012	belongs to the aldehyde dehydrogenase family
CCZ36_RS14695	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CCZ36_RS14695	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CCZ36_RS14705	COG1595	DNA-templated transcription, initiation
CCZ36_RS14740	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CCZ36_RS14745	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CCZ36_RS14755	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CCZ36_RS14775	COG0137	argininosuccinate synthase activity
CCZ36_RS14820	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CCZ36_RS14850	COG4585	Histidine kinase
CCZ36_RS14855	COG2197	response regulator
CCZ36_RS14875	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CCZ36_RS14890	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CCZ36_RS14955	COG3842	ATPase activity
CCZ36_RS14980	COG0215	cysteine-tRNA ligase activity
CCZ36_RS14985	COG3467	pyridoxamine 5'-phosphate
CCZ36_RS14995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CCZ36_RS15010	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CCZ36_RS15015	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CCZ36_RS15020	COG1329	Transcriptional regulator
CCZ36_RS15040	COG5002	protein histidine kinase activity
CCZ36_RS15055	COG0588	phosphoglycerate mutase activity
CCZ36_RS15110	COG2188	Transcriptional regulator
CCZ36_RS15165	COG0438	transferase activity, transferring glycosyl groups
CCZ36_RS15200	COG0789	Transcriptional regulator
CCZ36_RS15210	COG4942	peptidase
CCZ36_RS15230	COG4552	Acetyltransferase involved in intracellular survival and related
CCZ36_RS15245	COG1490	D-aminoacyl-tRNA deacylase activity
CCZ36_RS15255	COG0735	belongs to the Fur family
CCZ36_RS15260	COG3485	protocatechuate 3,4-dioxygenase
CCZ36_RS15285	COG2897	thiosulfate sulfurtransferase activity
CCZ36_RS15310	COG0745	RESPONSE REGULATOR receiver
CCZ36_RS15315	COG1609	Transcriptional regulator
CCZ36_RS15320	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CCZ36_RS15360	COG4977	sequence-specific DNA binding
CCZ36_RS15405	COG0737	Belongs to the 5'-nucleotidase family
CCZ36_RS15410	COG0456	acetyltransferase
CCZ36_RS15420	COG1725	Transcriptional regulator
CCZ36_RS15425	COG1116	anion transmembrane transporter activity
CCZ36_RS15445	COG0406	alpha-ribazole phosphatase activity
CCZ36_RS15445	COG0494	nUDIX hydrolase
CCZ36_RS15450	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CCZ36_RS15470	COG0306	phosphate transporter
CCZ36_RS15480	COG1937	Protein conserved in bacteria
CCZ36_RS15505	COG0671	phosphoesterase, PA-phosphatase related
CCZ36_RS15510	COG0739	heme binding
CCZ36_RS15510	COG0741	lytic transglycosylase activity
CCZ36_RS15510	COG1196	nuclear chromosome segregation
CCZ36_RS15580	COG1131	(ABC) transporter
CCZ36_RS15595	COG2197	response regulator
CCZ36_RS15620	COG1846	Transcriptional regulator
CCZ36_RS15635	COG1252	NADH dehydrogenase
CCZ36_RS15660	COG0579	oxidoreductase
CCZ36_RS15665	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CCZ36_RS15680	COG1196	nuclear chromosome segregation
CCZ36_RS15680	COG0741	lytic transglycosylase activity
CCZ36_RS15680	COG0739	heme binding
CCZ36_RS15700	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CCZ36_RS15700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CCZ36_RS15715	COG1937	Protein conserved in bacteria
CCZ36_RS15720	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
CCZ36_RS15730	COG2267	carboxylic ester hydrolase activity
CCZ36_RS15740	COG0513	Belongs to the DEAD box helicase family
CCZ36_RS15750	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CCZ36_RS15755	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CCZ36_RS15785	COG0785	Cytochrome C biogenesis protein
CCZ36_RS15790	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CCZ36_RS15790	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CCZ36_RS15800	COG1643	Atp-dependent helicase
CCZ36_RS15825	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CCZ36_RS15835	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CCZ36_RS15865	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CCZ36_RS15870	COG0047	phosphoribosylformylglycinamidine synthase activity
CCZ36_RS15875	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CCZ36_RS15910	COG2197	response regulator
CCZ36_RS15920	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CCZ36_RS15935	COG0151	Belongs to the GarS family
CCZ36_RS16020	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
CCZ36_RS16050	COG0490	domain, Protein
CCZ36_RS16055	COG0475	glutathione-regulated potassium exporter activity
CCZ36_RS16080	COG2255	four-way junction helicase activity
CCZ36_RS16090	COG0180	Tryptophanyl-tRNA synthetase
CCZ36_RS16095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CCZ36_RS16110	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CCZ36_RS16110	COG1672	PFAM Archaeal ATPase
CCZ36_RS16130	COG0431	NADPH-dependent FMN reductase
CCZ36_RS16160	COG2304	oxidoreductase activity
CCZ36_RS16165	COG2205	protein histidine kinase activity
CCZ36_RS16170	COG0745	RESPONSE REGULATOR receiver
CCZ36_RS16175	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CCZ36_RS16185	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CCZ36_RS16200	COG1741	Belongs to the pirin family
CCZ36_RS16210	COG1960	acyl-CoA dehydrogenase activity
CCZ36_RS16215	COG1362	aminopeptidase activity
CCZ36_RS16225	COG3903	Transcriptional regulator
CCZ36_RS16225	COG3629	intracellular signal transduction
CCZ36_RS16245	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CCZ36_RS16255	COG2271	Major facilitator Superfamily
CCZ36_RS16285	COG0508	dehydrogenase complex catalyzes the overall conversion of
CCZ36_RS16290	COG0022	dehydrogenase e1 component
CCZ36_RS16315	COG0515	serine threonine protein kinase
CCZ36_RS16320	COG0515	serine threonine protein kinase
CCZ36_RS16335	COG1136	(ABC) transporter
CCZ36_RS16335	COG4591	ABC-type transport system involved in lipoprotein release permease component
CCZ36_RS16385	COG1522	sequence-specific DNA binding
CCZ36_RS16390	COG1309	transcriptional regulator
CCZ36_RS16415	COG3396	Phenylacetate-CoA oxygenase
CCZ36_RS16420	COG3460	Phenylacetate-CoA oxygenase
CCZ36_RS16425	COG3396	Phenylacetate-CoA oxygenase
CCZ36_RS16430	COG2151	metal-sulfur cluster biosynthetic enzyme
CCZ36_RS16435	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CCZ36_RS16460	COG1733	regulation of RNA biosynthetic process
CCZ36_RS16465	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CCZ36_RS16480	COG1716	ATPase activity
CCZ36_RS16485	COG1716	ATPase activity
CCZ36_RS16500	COG0768	penicillin binding
CCZ36_RS16505	COG0515	serine threonine protein kinase
CCZ36_RS16510	COG3764	Sortase (surface protein transpeptidase)
CCZ36_RS16515	COG3764	Sortase (surface protein transpeptidase)
CCZ36_RS16545	COG0705	Rhomboid family
CCZ36_RS16580	COG3263	regulation of cellular component size
CCZ36_RS16595	COG2197	response regulator
CCZ36_RS16600	COG0586	Pfam SNARE associated Golgi protein
CCZ36_RS16615	COG1215	transferase activity, transferring glycosyl groups
CCZ36_RS16630	COG0438	transferase activity, transferring glycosyl groups
CCZ36_RS16685	COG0582	viral genome integration into host DNA
CCZ36_RS16995	COG4195	phage-related replication protein
CCZ36_RS17075	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CCZ36_RS17085	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
CCZ36_RS17090	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CCZ36_RS17095	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CCZ36_RS17100	COG0592	DNA-directed DNA polymerase activity
CCZ36_RS17115	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CCZ36_RS17125	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CCZ36_RS17130	COG0706	membrane insertase activity
CCZ36_RS17140	COG0357	Ribosomal RNA small subunit methyltransferase G
CCZ36_RS17145	COG1192	Involved in chromosome partitioning
CCZ36_RS17160	COG3118	belongs to the thioredoxin family
CCZ36_RS17165	COG0492	ferredoxin-NADP+ reductase activity
CCZ36_RS17175	COG1595	DNA-templated transcription, initiation
CCZ36_RS17180	COG0515	serine threonine protein kinase
CCZ36_RS17180	COG2815	serine threonine protein kinase
CCZ36_RS17195	COG0617	tRNA 3'-terminal CCA addition
CCZ36_RS17215	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CCZ36_RS17240	COG0360	Binds together with S18 to 16S ribosomal RNA
CCZ36_RS17245	COG0629	single-stranded DNA binding
CCZ36_RS17250	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CCZ36_RS17255	COG0359	binds to the 23S rRNA
CCZ36_RS17265	COG0305	Participates in initiation and elongation during chromosome replication
CCZ36_RS17290	COG2814	Major facilitator Superfamily
CCZ36_RS17310	COG0626	cystathionine gamma-synthase activity
CCZ36_RS17315	COG1950	PFAM Membrane protein of
CCZ36_RS17320	COG0662	Cupin 2, conserved barrel domain protein
CCZ36_RS17345	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CCZ36_RS17355	COG3152	Membrane
CCZ36_RS17365	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CCZ36_RS17370	COG1609	Transcriptional regulator
CCZ36_RS17375	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CCZ36_RS17380	COG1271	oxidase subunit
CCZ36_RS17385	COG1294	oxidase, subunit
CCZ36_RS17390	COG4988	ABC transporter
CCZ36_RS17400	COG0561	phosphatase activity
CCZ36_RS17410	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
CCZ36_RS17415	COG0789	Transcriptional regulator
CCZ36_RS17430	COG1131	(ABC) transporter
CCZ36_RS17455	COG0561	phosphatase activity
CCZ36_RS17460	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CCZ36_RS17470	COG2837	iron assimilation
CCZ36_RS17475	COG2372	response to copper ion
CCZ36_RS17485	COG1999	signal sequence binding
CCZ36_RS17505	COG0006	proline dipeptidase activity
CCZ36_RS17525	COG0653	protein targeting
CCZ36_RS17540	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CCZ36_RS17595	COG3693	PFAM glycoside hydrolase, family 10
CCZ36_RS17615	COG1595	DNA-templated transcription, initiation
CCZ36_RS17620	COG0318	PFAM AMP-dependent synthetase and ligase
CCZ36_RS17665	COG1252	NADH dehydrogenase
CCZ36_RS17670	COG1595	DNA-templated transcription, initiation
CCZ36_RS17695	COG0745	RESPONSE REGULATOR receiver
CCZ36_RS17715	COG0477	Major facilitator Superfamily
CCZ36_RS17735	COG3467	pyridoxamine 5'-phosphate
CCZ36_RS17740	COG2353	YceI-like domain
CCZ36_RS17750	COG1846	Transcriptional regulator
CCZ36_RS17765	COG1191	sigma factor activity
CCZ36_RS17770	COG1191	sigma factor activity
CCZ36_RS17920	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CCZ36_RS17945	COG4941	Belongs to the sigma-70 factor family
CCZ36_RS17975	COG2268	Band 7 protein
CCZ36_RS17985	COG0450	alkyl hydroperoxide reductase
CCZ36_RS18040	COG1278	Cold shock
CCZ36_RS18045	COG0513	Belongs to the DEAD box helicase family
CCZ36_RS18050	COG3594	Acyltransferase
CCZ36_RS18055	COG0475	glutathione-regulated potassium exporter activity
CCZ36_RS18065	COG0531	amino acid
CCZ36_RS18110	COG1024	Enoyl-CoA hydratase
CCZ36_RS18115	COG2124	cytochrome p450
CCZ36_RS18120	COG2124	cytochrome p450
CCZ36_RS18145	COG2197	response regulator
CCZ36_RS18150	COG4585	Histidine kinase
CCZ36_RS18210	COG1609	Transcriptional regulator
CCZ36_RS18225	COG0745	RESPONSE REGULATOR receiver
CCZ36_RS18230	COG2205	protein histidine kinase activity
CCZ36_RS18320	COG0277	FAD linked oxidase domain protein
CCZ36_RS18340	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CCZ36_RS18405	COG2197	response regulator
CCZ36_RS18425	COG3209	COG3209 Rhs family protein
CCZ36_RS18460	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CCZ36_RS18500	COG1396	sequence-specific DNA binding
CCZ36_RS18520	COG1609	Transcriptional regulator
CCZ36_RS18590	COG0717	Belongs to the dCTP deaminase family
CCZ36_RS18610	COG2181	nitrate reductase activity
CCZ36_RS18610	COG0247	lactate metabolic process
CCZ36_RS18615	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CCZ36_RS18620	COG0443	Heat shock 70 kDa protein
CCZ36_RS18625	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CCZ36_RS18630	COG0484	heat shock protein binding
CCZ36_RS18635	COG0789	Transcriptional regulator
CCZ36_RS18670	COG0542	response to heat
CCZ36_RS18695	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CCZ36_RS18710	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CCZ36_RS18715	COG0191	fructose-bisphosphate aldolase activity
CCZ36_RS18720	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CCZ36_RS18725	COG0477	Major facilitator Superfamily
CCZ36_RS18740	COG3844	kynureninase activity
CCZ36_RS18750	COG4585	Histidine kinase
CCZ36_RS18755	COG2197	response regulator
CCZ36_RS18780	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CCZ36_RS18785	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CCZ36_RS18795	COG0590	tRNA wobble adenosine to inosine editing
CCZ36_RS18795	COG0037	tRNA processing
CCZ36_RS18800	COG2076	Multidrug Resistance protein
CCZ36_RS18850	COG1960	acyl-CoA dehydrogenase activity
CCZ36_RS18855	COG0662	Cupin 2, conserved barrel domain protein
CCZ36_RS18865	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CCZ36_RS18890	COG0667	Aldo Keto reductase
CCZ36_RS18945	COG3226	Transcriptional regulator
CCZ36_RS18950	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CCZ36_RS18950	COG0515	serine threonine protein kinase
CCZ36_RS18960	COG0693	protein deglycase activity
CCZ36_RS18965	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CCZ36_RS18970	COG1802	Transcriptional regulator
CCZ36_RS18985	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CCZ36_RS18990	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CCZ36_RS19000	COG0702	epimerase
CCZ36_RS19025	COG1595	DNA-templated transcription, initiation
CCZ36_RS19045	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CCZ36_RS19055	COG2755	lipolytic protein G-D-S-L family
CCZ36_RS19090	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CCZ36_RS19110	COG1408	metallophosphoesterase
CCZ36_RS19115	COG1610	YqeY-like protein
CCZ36_RS19120	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CCZ36_RS19135	COG0003	Pfam Anion-transporting ATPase
CCZ36_RS19160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CCZ36_RS19195	COG2267	carboxylic ester hydrolase activity
CCZ36_RS19205	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CCZ36_RS19210	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CCZ36_RS19280	COG1366	Belongs to the anti-sigma-factor antagonist family
CCZ36_RS19285	COG2172	sigma factor antagonist activity
CCZ36_RS19290	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CCZ36_RS19300	COG2890	protein-(glutamine-N5) methyltransferase activity
CCZ36_RS19310	COG1754	DNA topoisomerase type I activity
CCZ36_RS19310	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CCZ36_RS19315	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CCZ36_RS19320	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CCZ36_RS19410	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CCZ36_RS19415	COG1116	anion transmembrane transporter activity
CCZ36_RS19415	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CCZ36_RS19435	COG0529	Catalyzes the synthesis of activated sulfate
CCZ36_RS19440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CCZ36_RS19470	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CCZ36_RS19480	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CCZ36_RS19490	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CCZ36_RS19495	COG1181	Belongs to the D-alanine--D-alanine ligase family
CCZ36_RS19515	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CCZ36_RS19540	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CCZ36_RS19545	COG2197	response regulator
CCZ36_RS19550	COG4585	Histidine kinase
CCZ36_RS19555	COG1136	(ABC) transporter
CCZ36_RS19555	COG0577	efflux transmembrane transporter activity
CCZ36_RS19560	COG0577	efflux transmembrane transporter activity
CCZ36_RS19565	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CCZ36_RS19565	COG0561	phosphatase activity
CCZ36_RS19570	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CCZ36_RS19575	COG0463	Glycosyl transferase, family 2
CCZ36_RS19625	COG1132	(ABC) transporter
CCZ36_RS19635	COG1595	DNA-templated transcription, initiation
CCZ36_RS19660	COG1846	Transcriptional regulator
CCZ36_RS19725	COG0395	ABC-type sugar transport system, permease component
CCZ36_RS19730	COG1175	transmembrane transport
CCZ36_RS19770	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CCZ36_RS19770	COG1263	PTS System
CCZ36_RS19775	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CCZ36_RS19780	COG1737	Transcriptional regulator
CCZ36_RS19810	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CCZ36_RS19815	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CCZ36_RS19820	COG1984	allophanate hydrolase subunit 2
CCZ36_RS19835	COG3973	AAA domain
CCZ36_RS19845	COG1061	Type III restriction enzyme res subunit
CCZ36_RS19880	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CCZ36_RS19885	COG1120	ATPase activity
CCZ36_RS19890	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CCZ36_RS19895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CCZ36_RS19910	COG1278	Cold shock
CCZ36_RS19915	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
CCZ36_RS19920	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CCZ36_RS19930	COG2814	Major facilitator Superfamily
CCZ36_RS19955	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CCZ36_RS19965	COG2252	PERMEase
CCZ36_RS19995	COG0697	spore germination
CCZ36_RS20000	COG0778	Nitroreductase
CCZ36_RS20005	COG1846	Transcriptional regulator
CCZ36_RS20010	COG0667	Aldo Keto reductase
CCZ36_RS20030	COG2267	carboxylic ester hydrolase activity
CCZ36_RS20040	COG0515	serine threonine protein kinase
CCZ36_RS20045	COG1028	Short-chain dehydrogenase reductase Sdr
CCZ36_RS20050	COG1028	Short-chain dehydrogenase reductase Sdr
CCZ36_RS20055	COG0583	DNA-binding transcription factor activity
CCZ36_RS20160	COG1309	transcriptional regulator
CCZ36_RS20215	COG1335	isochorismatase
CCZ36_RS20235	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CCZ36_RS20265	COG2205	protein histidine kinase activity
CCZ36_RS20270	COG0277	FAD linked oxidase domain protein
CCZ36_RS20270	COG0247	lactate metabolic process
CCZ36_RS20275	COG0583	DNA-binding transcription factor activity
CCZ36_RS20285	COG2402	Toxic component of a toxin-antitoxin (TA) module. An RNase
CCZ36_RS20295	COG4221	oxidoreductase activity
CCZ36_RS20300	COG1309	transcriptional regulator
CCZ36_RS20305	COG0494	nUDIX hydrolase
CCZ36_RS20320	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CCZ36_RS20335	COG0318	PFAM AMP-dependent synthetase and ligase
CCZ36_RS20340	COG1024	Enoyl-CoA hydratase
CCZ36_RS20365	COG2154	pterin-4-alpha-carbinolamine dehydratase
CCZ36_RS20395	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CCZ36_RS20445	COG0259	pyridoxamine-phosphate oxidase activity
CCZ36_RS20455	COG1136	(ABC) transporter
CCZ36_RS20455	COG0577	efflux transmembrane transporter activity
CCZ36_RS20460	COG1136	(ABC) transporter
CCZ36_RS20460	COG0577	efflux transmembrane transporter activity
CCZ36_RS20475	COG0745	RESPONSE REGULATOR receiver
CCZ36_RS20485	COG4821	SIS domain
CCZ36_RS20495	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CCZ36_RS20505	COG1131	(ABC) transporter
CCZ36_RS20550	COG1366	Belongs to the anti-sigma-factor antagonist family
CCZ36_RS20655	COG2072	flavoprotein involved in K transport
CCZ36_RS20680	COG0501	Belongs to the peptidase M48B family
CCZ36_RS20685	COG0259	pyridoxamine-phosphate oxidase activity
CCZ36_RS20695	COG1309	transcriptional regulator
CCZ36_RS20735	COG1278	Cold shock
CCZ36_RS20740	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
CCZ36_RS20750	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CCZ36_RS20755	COG1228	amidohydrolase
CCZ36_RS20775	COG2226	methyltransferase
CCZ36_RS20815	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CCZ36_RS20820	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CCZ36_RS20825	COG0649	NAD binding
CCZ36_RS20835	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CCZ36_RS20840	COG1034	ATP synthesis coupled electron transport
CCZ36_RS20845	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CCZ36_RS20850	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CCZ36_RS20855	COG0839	Belongs to the complex I subunit 6 family
CCZ36_RS20860	COG0713	ATP synthesis coupled electron transport
CCZ36_RS20865	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CCZ36_RS20875	COG1007	ATP synthesis coupled electron transport
CCZ36_RS20880	COG0514	ATP-dependent DNA helicase (RecQ)
CCZ36_RS20910	COG0179	Fumarylacetoacetate (FAA) hydrolase
CCZ36_RS20920	COG3104	oligopeptide transport
CCZ36_RS20925	COG0142	geranyltranstransferase activity
CCZ36_RS20935	COG1131	(ABC) transporter
CCZ36_RS20950	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CCZ36_RS20950	COG0515	serine threonine protein kinase
CCZ36_RS20970	COG0561	phosphatase activity
CCZ36_RS21030	COG0702	epimerase
CCZ36_RS21035	COG1013	pyruvate-flavodoxin oxidoreductase activity
CCZ36_RS21040	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CCZ36_RS21040	COG0674	pyruvate-flavodoxin oxidoreductase activity
CCZ36_RS21060	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CCZ36_RS21065	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CCZ36_RS21075	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CCZ36_RS21080	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CCZ36_RS21085	COG0839	Belongs to the complex I subunit 6 family
CCZ36_RS21090	COG0713	ATP synthesis coupled electron transport
CCZ36_RS21095	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CCZ36_RS21105	COG1007	ATP synthesis coupled electron transport
CCZ36_RS21115	COG0501	Belongs to the peptidase M48B family
CCZ36_RS21120	COG3304	Inner membrane component domain
CCZ36_RS21135	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CCZ36_RS21140	COG1666	GTP binding
CCZ36_RS21210	COG2188	Transcriptional regulator
CCZ36_RS21215	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CCZ36_RS21235	COG0702	epimerase
CCZ36_RS21255	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CCZ36_RS21260	COG2030	dehydratase
CCZ36_RS21270	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CCZ36_RS21275	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CCZ36_RS21280	COG0436	Aminotransferase
CCZ36_RS21300	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CCZ36_RS21305	COG0081	regulation of translation
CCZ36_RS21315	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CCZ36_RS21320	COG0222	ribosome binding
CCZ36_RS21330	COG0085	RNA polymerase activity
CCZ36_RS21335	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CCZ36_RS21345	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CCZ36_RS21350	COG0049	tRNA binding
CCZ36_RS21355	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CCZ36_RS21360	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CCZ36_RS21385	COG0051	transcription antitermination factor activity, RNA binding
CCZ36_RS21390	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CCZ36_RS21395	COG0088	Forms part of the polypeptide exit tunnel
CCZ36_RS21400	COG0089	rRNA binding
CCZ36_RS21405	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CCZ36_RS21410	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CCZ36_RS21415	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CCZ36_RS21420	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CCZ36_RS21425	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CCZ36_RS21430	COG0255	Belongs to the universal ribosomal protein uL29 family
CCZ36_RS21435	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CCZ36_RS21440	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CCZ36_RS21445	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CCZ36_RS21450	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CCZ36_RS21455	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CCZ36_RS21465	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CCZ36_RS21470	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CCZ36_RS21475	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CCZ36_RS21480	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CCZ36_RS21485	COG1841	ribosomal large subunit assembly
CCZ36_RS21490	COG0200	Binds to the 23S rRNA
CCZ36_RS21500	COG0563	adenylate kinase activity
CCZ36_RS21510	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CCZ36_RS21515	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CCZ36_RS21520	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CCZ36_RS21525	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CCZ36_RS21530	COG0202	RNA polymerase activity
CCZ36_RS21535	COG0203	ribosomal protein L17
CCZ36_RS21540	COG0101	tRNA pseudouridine synthase activity
CCZ36_RS21550	COG0488	(ABC) transporter
CCZ36_RS21555	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CCZ36_RS21560	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CCZ36_RS21565	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CCZ36_RS21575	COG1072	(Pantothenic acid kinase))
CCZ36_RS21615	COG3795	YCII-related domain
CCZ36_RS21620	COG4941	Belongs to the sigma-70 factor family
CCZ36_RS21635	COG0596	Alpha beta hydrolase
CCZ36_RS21650	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CCZ36_RS21655	COG0736	holo-[acyl-carrier-protein] synthase activity
CCZ36_RS21665	COG3189	MarR family transcriptional regulator
CCZ36_RS21670	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CCZ36_RS21680	COG0802	atpase or kinase
CCZ36_RS21705	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CCZ36_RS21730	COG0726	polysaccharide deacetylase
CCZ36_RS21740	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CCZ36_RS21755	COG2132	Multicopper oxidase
CCZ36_RS21770	COG0583	DNA-binding transcription factor activity
CCZ36_RS21785	COG1595	DNA-templated transcription, initiation
CCZ36_RS21795	COG0516	GMP reductase activity
CCZ36_RS21825	COG0515	serine threonine protein kinase
CCZ36_RS21830	COG1012	belongs to the aldehyde dehydrogenase family
CCZ36_RS21850	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CCZ36_RS21850	COG0519	Catalyzes the synthesis of GMP from XMP
CCZ36_RS21860	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CCZ36_RS21870	COG2814	Major facilitator Superfamily
CCZ36_RS21910	COG2197	response regulator
CCZ36_RS21935	COG0739	heme binding
CCZ36_RS21945	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CCZ36_RS21965	COG0714	Associated with various cellular activities
CCZ36_RS21975	COG3552	Protein containing von Willebrand factor type A (VWA) domain
CCZ36_RS21995	COG0045	succinate-CoA ligase (ADP-forming) activity
CCZ36_RS22025	COG0138	bifunctional purine biosynthesis protein purh
CCZ36_RS22040	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CCZ36_RS22055	COG0039	L-malate dehydrogenase activity
CCZ36_RS22060	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CCZ36_RS22065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CCZ36_RS22075	COG0754	glutathionylspermidine amidase activity
CCZ36_RS22080	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CCZ36_RS22085	COG0180	Tryptophanyl-tRNA synthetase
CCZ36_RS22105	COG1295	ribonuclease BN
CCZ36_RS22115	COG1408	metallophosphoesterase
CCZ36_RS22150	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CCZ36_RS22165	COG2009	succinate dehydrogenase
CCZ36_RS22200	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CCZ36_RS22205	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CCZ36_RS22210	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CCZ36_RS22215	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CCZ36_RS22230	COG0733	neurotransmitter:sodium symporter activity
CCZ36_RS22240	COG1595	DNA-templated transcription, initiation
CCZ36_RS22265	COG1216	Glycosyl transferase, family 2
CCZ36_RS22295	COG1216	Glycosyl transferase, family 2
CCZ36_RS22305	COG1083	cytidylyl-transferase
CCZ36_RS22310	COG2089	acid synthase
CCZ36_RS22320	COG1473	amidohydrolase
CCZ36_RS22320	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CCZ36_RS22325	COG1744	ABC transporter substrate-binding protein PnrA-like
CCZ36_RS22330	COG3845	ABC transporter
CCZ36_RS22335	COG4603	Belongs to the binding-protein-dependent transport system permease family
CCZ36_RS22340	COG1079	Belongs to the binding-protein-dependent transport system permease family
CCZ36_RS22355	COG1404	Belongs to the peptidase S8 family
CCZ36_RS22375	COG2814	Major facilitator Superfamily
CCZ36_RS22380	COG0583	DNA-binding transcription factor activity
CCZ36_RS22395	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CCZ36_RS22420	COG2205	protein histidine kinase activity
CCZ36_RS22425	COG0745	RESPONSE REGULATOR receiver
CCZ36_RS22430	COG1595	DNA-templated transcription, initiation
CCZ36_RS22460	COG1012	belongs to the aldehyde dehydrogenase family
CCZ36_RS22465	COG1012	belongs to the aldehyde dehydrogenase family
CCZ36_RS22480	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CCZ36_RS22520	COG4770	biotin carboxylase activity
CCZ36_RS22530	COG0424	maF-like protein
CCZ36_RS22540	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CCZ36_RS22555	COG1024	Enoyl-CoA hydratase
CCZ36_RS22580	COG1376	ErfK ybiS ycfS ynhG family protein
CCZ36_RS22595	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CCZ36_RS22605	COG1396	sequence-specific DNA binding
CCZ36_RS22610	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CCZ36_RS22620	COG0501	Belongs to the peptidase M48B family
CCZ36_RS22645	COG1595	DNA-templated transcription, initiation
CCZ36_RS22650	COG2255	four-way junction helicase activity
CCZ36_RS22655	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CCZ36_RS22670	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CCZ36_RS22680	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CCZ36_RS22710	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CCZ36_RS22730	COG1331	Highly conserved protein containing a thioredoxin domain
CCZ36_RS22740	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CCZ36_RS22770	COG0436	Aminotransferase
CCZ36_RS22790	COG1733	regulation of RNA biosynthetic process
CCZ36_RS22810	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CCZ36_RS22825	COG1414	Transcriptional regulator
CCZ36_RS22830	COG0251	oxidation-reduction process
CCZ36_RS22835	COG2610	gluconate transmembrane transporter activity
CCZ36_RS22865	COG2894	cell division
CCZ36_RS22895	COG3920	Histidine kinase
CCZ36_RS22920	COG2885	chlorophyll binding
CCZ36_RS22980	COG0667	Aldo Keto reductase
CCZ36_RS22985	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CCZ36_RS22990	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CCZ36_RS23005	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CCZ36_RS23010	COG0450	alkyl hydroperoxide reductase
CCZ36_RS23025	COG1136	(ABC) transporter
CCZ36_RS23045	COG4499	WXG100 protein secretion system (Wss), protein YukC
CCZ36_RS23045	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CCZ36_RS23060	COG0114	fumarate hydratase activity
CCZ36_RS23070	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CCZ36_RS23075	COG1028	Short-chain dehydrogenase reductase Sdr
CCZ36_RS23085	COG1362	aminopeptidase activity
CCZ36_RS23095	COG3321	synthase
CCZ36_RS23095	COG0604	alcohol dehydrogenase
CCZ36_RS23110	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CCZ36_RS23110	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CCZ36_RS23135	COG0778	Nitroreductase
CCZ36_RS23140	COG1722	exodeoxyribonuclease VII activity
CCZ36_RS23145	COG1570	exodeoxyribonuclease VII activity
CCZ36_RS23155	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CCZ36_RS23170	COG0012	GTP binding
CCZ36_RS23200	COG1846	Transcriptional regulator
CCZ36_RS23205	COG1920	GTP binding
CCZ36_RS23215	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CCZ36_RS23220	COG0604	alcohol dehydrogenase
CCZ36_RS23220	COG3321	synthase
CCZ36_RS23230	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CCZ36_RS23235	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CCZ36_RS23245	COG2867	negative regulation of translational initiation
CCZ36_RS23255	COG2977	Belongs to the P-Pant transferase superfamily
CCZ36_RS23275	COG0667	Aldo Keto reductase
CCZ36_RS23295	COG0546	phosphoglycolate phosphatase activity
CCZ36_RS23315	COG0477	Major facilitator Superfamily
CCZ36_RS23325	COG2197	response regulator
CCZ36_RS23335	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CCZ36_RS23365	COG1554	hydrolase, family 65, central catalytic
CCZ36_RS23410	COG1842	Phage shock protein A
CCZ36_RS23420	COG0463	Glycosyl transferase, family 2
CCZ36_RS23440	COG1012	belongs to the aldehyde dehydrogenase family
CCZ36_RS23455	COG2208	phosphoserine phosphatase activity
CCZ36_RS23455	COG2770	Histidine kinase
CCZ36_RS23525	COG0395	ABC-type sugar transport system, permease component
CCZ36_RS23530	COG1175	transmembrane transport
CCZ36_RS23550	COG1609	Transcriptional regulator
CCZ36_RS23560	COG1217	gtp-binding protein TYPA
CCZ36_RS23565	COG4166	transmembrane transport
CCZ36_RS23570	COG0601	transmembrane transport
CCZ36_RS23575	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CCZ36_RS23585	COG4608	Belongs to the ABC transporter superfamily
CCZ36_RS23590	COG4166	transmembrane transport
CCZ36_RS23595	COG0601	transmembrane transport
CCZ36_RS23600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CCZ36_RS23605	COG0444	Belongs to the ABC transporter superfamily
CCZ36_RS23610	COG4608	Belongs to the ABC transporter superfamily
CCZ36_RS23630	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CCZ36_RS23655	COG0110	maltose O-acetyltransferase activity
CCZ36_RS23685	COG1132	(ABC) transporter
CCZ36_RS23690	COG2197	response regulator
CCZ36_RS23695	COG2912	Transglutaminase-like superfamily
CCZ36_RS23725	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CCZ36_RS23730	COG1611	Belongs to the LOG family
CCZ36_RS23735	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CCZ36_RS23745	COG0519	Catalyzes the synthesis of GMP from XMP
CCZ36_RS23750	COG1024	Enoyl-CoA hydratase
CCZ36_RS23765	COG1595	DNA-templated transcription, initiation
CCZ36_RS23775	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CCZ36_RS23780	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CCZ36_RS23815	COG0598	Magnesium transport protein CorA
CCZ36_RS23830	COG2814	Major facilitator Superfamily
CCZ36_RS23845	COG2095	MarC family integral membrane protein
CCZ36_RS23850	COG1432	Conserved Protein
CCZ36_RS23860	COG0513	Belongs to the DEAD box helicase family
CCZ36_RS23990	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CCZ36_RS24050	COG1615	UPF0182 protein
CCZ36_RS24075	COG0753	catalase activity
CCZ36_RS24085	COG0483	inositol monophosphate 1-phosphatase activity
CCZ36_RS24095	COG2076	Multidrug Resistance protein
CCZ36_RS24100	COG1162	GTPase activity
CCZ36_RS24105	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CCZ36_RS24115	COG2135	peptidase activity
CCZ36_RS24125	COG1595	DNA-templated transcription, initiation
CCZ36_RS24130	COG5662	AntiSigma factor
CCZ36_RS24150	COG0242	peptide deformylase activity
CCZ36_RS24210	COG1966	Carbon starvation protein
CCZ36_RS24225	COG1216	Glycosyl transferase, family 2
CCZ36_RS24225	COG1442	glycosyl transferase family 8
CCZ36_RS24235	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CCZ36_RS24240	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CCZ36_RS24245	COG0109	protoheme IX farnesyltransferase activity
CCZ36_RS24250	COG1215	transferase activity, transferring glycosyl groups
CCZ36_RS24270	COG0667	Aldo Keto reductase
CCZ36_RS24280	COG2182	Extracellular solute-binding protein
CCZ36_RS24285	COG1175	transmembrane transport
CCZ36_RS24290	COG0395	ABC-type sugar transport system, permease component
CCZ36_RS24295	COG1472	Belongs to the glycosyl hydrolase 3 family
CCZ36_RS24300	COG0363	glucosamine-6-phosphate deaminase activity
CCZ36_RS24305	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CCZ36_RS24325	COG1597	lipid kinase activity
CCZ36_RS24340	COG2172	sigma factor antagonist activity
CCZ36_RS24350	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CCZ36_RS24355	COG1017	nitric oxide dioxygenase activity
CCZ36_RS24355	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CCZ36_RS24360	COG1959	2 iron, 2 sulfur cluster binding
CCZ36_RS24365	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CCZ36_RS24370	COG0142	geranyltranstransferase activity
CCZ36_RS24440	COG4585	Histidine kinase
CCZ36_RS24465	COG0659	secondary active sulfate transmembrane transporter activity
CCZ36_RS24545	COG0582	viral genome integration into host DNA
CCZ36_RS24565	COG4106	trans-aconitate 2-methyltransferase activity
CCZ36_RS24570	COG1126	abc transporter atp-binding protein
CCZ36_RS24575	COG0765	amino acid transport
CCZ36_RS24580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CCZ36_RS24585	COG0281	malic enzyme
CCZ36_RS24590	COG0604	alcohol dehydrogenase
CCZ36_RS24610	COG0542	response to heat
CCZ36_RS24635	COG0508	dehydrogenase complex catalyzes the overall conversion of
CCZ36_RS24635	COG0567	Dehydrogenase, E1 component
CCZ36_RS24640	COG2205	protein histidine kinase activity
CCZ36_RS24645	COG0745	RESPONSE REGULATOR receiver
CCZ36_RS24655	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CCZ36_RS24660	COG0726	polysaccharide deacetylase
CCZ36_RS24675	COG5002	protein histidine kinase activity
CCZ36_RS24700	COG0791	NLP P60 protein
CCZ36_RS24720	COG1309	transcriptional regulator
CCZ36_RS24745	COG0768	penicillin binding
CCZ36_RS24760	COG2205	protein histidine kinase activity
CCZ36_RS24780	COG3285	dna ligase
CCZ36_RS24780	COG1793	dna ligase
CCZ36_RS24785	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CCZ36_RS24800	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CCZ36_RS24830	COG0018	arginyl-trna synthetase
CCZ36_RS24835	COG0019	diaminopimelate decarboxylase activity
CCZ36_RS24840	COG0460	homoserine dehydrogenase
CCZ36_RS24845	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CCZ36_RS24850	COG0083	homoserine kinase activity
CCZ36_RS24865	COG1316	TRANSCRIPTIONal
CCZ36_RS24870	COG0254	rRNA binding
CCZ36_RS24875	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CCZ36_RS24880	COG2890	protein-(glutamine-N5) methyltransferase activity
CCZ36_RS24895	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CCZ36_RS24915	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CCZ36_RS24920	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CCZ36_RS24925	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CCZ36_RS24930	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CCZ36_RS24935	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CCZ36_RS24940	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CCZ36_RS24945	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CCZ36_RS24960	COG2197	response regulator
CCZ36_RS24965	COG4585	Histidine kinase
CCZ36_RS24980	COG1250	3-hydroxyacyl-CoA dehydrogenase
CCZ36_RS24995	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
CCZ36_RS25005	COG0586	Pfam SNARE associated Golgi protein
CCZ36_RS25025	COG4585	Histidine kinase
CCZ36_RS25060	COG1131	(ABC) transporter
CCZ36_RS25080	COG0183	Belongs to the thiolase family
CCZ36_RS25095	COG0745	RESPONSE REGULATOR receiver
CCZ36_RS25100	COG5000	phosphorelay sensor kinase activity
CCZ36_RS25100	COG5002	protein histidine kinase activity
CCZ36_RS25170	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CCZ36_RS25170	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CCZ36_RS25210	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CCZ36_RS25215	COG0857	belongs to the CobB CobQ family
CCZ36_RS25215	COG0280	phosphate acetyltransferase
CCZ36_RS25220	COG0205	6-phosphofructokinase activity
CCZ36_RS25230	COG4565	transcriptional regulatory protein
CCZ36_RS25235	COG3290	protein histidine kinase activity
CCZ36_RS25240	COG1301	dicarboxylic acid transport
CCZ36_RS25250	COG3118	belongs to the thioredoxin family
CCZ36_RS25255	COG2084	Dehydrogenase
CCZ36_RS25260	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CCZ36_RS25265	COG3281	Trehalose synthase
CCZ36_RS25270	COG0366	Alpha amylase catalytic
CCZ36_RS25275	COG0366	Alpha amylase catalytic
CCZ36_RS25280	COG0058	SHG alpha-glucan phosphorylase activity
CCZ36_RS25345	COG1132	(ABC) transporter
CCZ36_RS25350	COG1132	(ABC) transporter
CCZ36_RS25355	COG1131	(ABC) transporter
CCZ36_RS25370	COG2197	response regulator
CCZ36_RS25420	COG2197	response regulator
CCZ36_RS25425	COG3851	Histidine kinase
CCZ36_RS25430	COG0586	Pfam SNARE associated Golgi protein
CCZ36_RS25530	COG0823	Involved in the tonB-independent uptake of proteins
CCZ36_RS25530	COG1506	peptidase
CCZ36_RS25540	COG0464	growth
CCZ36_RS25545	COG2235	arginine
CCZ36_RS25560	COG4166	transmembrane transport
CCZ36_RS25570	COG4566	intracellular signal transduction
CCZ36_RS25585	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CCZ36_RS25600	COG1760	l-serine dehydratase
CCZ36_RS25605	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CCZ36_RS25610	COG0509	glycine decarboxylation via glycine cleavage system
CCZ36_RS25615	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CCZ36_RS25620	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CCZ36_RS25635	COG0747	negative chemotaxis
CCZ36_RS25640	COG0601	transmembrane transport
CCZ36_RS25645	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CCZ36_RS25655	COG4608	Belongs to the ABC transporter superfamily
CCZ36_RS25660	COG2860	membrane
CCZ36_RS25670	COG0789	Transcriptional regulator
CCZ36_RS25700	COG0482	sulfurtransferase activity
CCZ36_RS25720	COG4221	oxidoreductase activity
CCZ36_RS25730	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CCZ36_RS25740	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CCZ36_RS25745	COG0154	amidase activity
CCZ36_RS25755	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CCZ36_RS25760	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CCZ36_RS25770	COG2409	Drug exporters of the RND superfamily
CCZ36_RS25785	COG2197	response regulator
CCZ36_RS25795	COG0667	Aldo Keto reductase
CCZ36_RS25805	COG5001	Diguanylate cyclase
CCZ36_RS25805	COG3300	MHYT domain
CCZ36_RS25815	COG0440	acetolactate synthase activity
CCZ36_RS25820	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CCZ36_RS25825	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CCZ36_RS25850	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CCZ36_RS25870	COG2508	Transcriptional regulator
CCZ36_RS25875	COG0506	proline dehydrogenase activity
CCZ36_RS25880	COG1012	belongs to the aldehyde dehydrogenase family
CCZ36_RS25900	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CCZ36_RS25905	COG2957	Belongs to the agmatine deiminase family
CCZ36_RS25915	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CCZ36_RS25920	COG1609	Transcriptional regulator
CCZ36_RS25935	COG0601	transmembrane transport
CCZ36_RS25940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CCZ36_RS25945	COG0444	Belongs to the ABC transporter superfamily
CCZ36_RS25955	COG1472	Belongs to the glycosyl hydrolase 3 family
CCZ36_RS25985	COG1309	transcriptional regulator
CCZ36_RS25990	COG2084	Dehydrogenase
CCZ36_RS25995	COG3708	Transcriptional regulator
CCZ36_RS25995	COG2207	Transcriptional regulator
CCZ36_RS26020	COG0492	ferredoxin-NADP+ reductase activity
CCZ36_RS26075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CCZ36_RS26080	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CCZ36_RS26085	COG1120	ATPase activity
CCZ36_RS26090	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CCZ36_RS26110	COG0366	Alpha amylase catalytic
CCZ36_RS26110	COG1470	cell adhesion involved in biofilm formation
CCZ36_RS26115	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CCZ36_RS26135	COG2018	Roadblock/LC7 domain
CCZ36_RS26155	COG2018	Roadblock/LC7 domain
CCZ36_RS26160	COG5002	protein histidine kinase activity
CCZ36_RS26170	COG0179	Fumarylacetoacetate (FAA) hydrolase
CCZ36_RS26175	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CCZ36_RS26210	COG1414	Transcriptional regulator
CCZ36_RS26215	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CCZ36_RS26220	COG0066	3-isopropylmalate dehydratase activity
CCZ36_RS26230	COG0776	regulation of translation
CCZ36_RS26240	COG1920	GTP binding
CCZ36_RS26250	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CCZ36_RS26255	COG1181	Belongs to the D-alanine--D-alanine ligase family
CCZ36_RS26275	COG0351	phosphomethylpyrimidine kinase
CCZ36_RS26280	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CCZ36_RS26285	COG1461	Dihydroxyacetone kinase
CCZ36_RS26290	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CCZ36_RS26295	COG0742	ribosomal rna small subunit methyltransferase
CCZ36_RS26300	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CCZ36_RS26315	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CCZ36_RS26320	COG0571	ribonuclease III activity
CCZ36_RS26325	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CCZ36_RS26330	COG1733	regulation of RNA biosynthetic process
CCZ36_RS26345	COG0546	phosphoglycolate phosphatase activity
CCZ36_RS26380	COG2340	Cysteine-rich secretory protein family
CCZ36_RS26385	COG1254	Belongs to the acylphosphatase family
CCZ36_RS26400	COG1196	nuclear chromosome segregation
CCZ36_RS26405	COG0477	Major facilitator Superfamily
CCZ36_RS26440	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CCZ36_RS26460	COG0228	four-way junction DNA binding
CCZ36_RS26465	COG1837	Belongs to the UPF0109 family
CCZ36_RS26470	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CCZ36_RS26475	COG0336	Belongs to the RNA methyltransferase TrmD family
CCZ36_RS26480	COG0335	large ribosomal subunit rRNA binding
CCZ36_RS26495	COG0681	Belongs to the peptidase S26 family
CCZ36_RS26515	COG0792	nuclease activity
CCZ36_RS26530	COG1191	sigma factor activity
CCZ36_RS26545	COG0052	Belongs to the universal ribosomal protein uS2 family
CCZ36_RS26550	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CCZ36_RS26555	COG0528	UMP kinase activity
CCZ36_RS26560	COG0233	cytoplasmic translational termination
CCZ36_RS26565	COG0575	Belongs to the CDS family
CCZ36_RS26570	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CCZ36_RS26585	COG3842	ATPase activity
CCZ36_RS26590	COG2197	response regulator
CCZ36_RS26595	COG4585	Histidine kinase
CCZ36_RS26605	COG0438	transferase activity, transferring glycosyl groups
CCZ36_RS26620	COG4181	ATPase activity
CCZ36_RS26625	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CCZ36_RS26635	COG1012	belongs to the aldehyde dehydrogenase family
CCZ36_RS26660	COG4585	Histidine kinase
CCZ36_RS26675	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CCZ36_RS26695	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CCZ36_RS26700	COG3842	ATPase activity
CCZ36_RS26705	COG1176	ABC-type spermidine putrescine transport system, permease component I
CCZ36_RS26710	COG1177	transmembrane transport
CCZ36_RS26715	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CCZ36_RS26745	COG2508	Transcriptional regulator
CCZ36_RS26750	COG1012	belongs to the aldehyde dehydrogenase family
CCZ36_RS26760	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CCZ36_RS26765	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CCZ36_RS26770	COG0750	zinc metalloprotease
CCZ36_RS26775	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CCZ36_RS26790	COG0442	prolyl-tRNA aminoacylation
CCZ36_RS26810	COG0779	Required for maturation of 30S ribosomal subunits
CCZ36_RS26825	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CCZ36_RS26835	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CCZ36_RS26840	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CCZ36_RS26885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CCZ36_RS26890	COG0601	transmembrane transport
CCZ36_RS26895	COG0747	negative chemotaxis
CCZ36_RS26900	COG0455	bacterial-type flagellum organization
CCZ36_RS26920	COG3266	domain, Protein
CCZ36_RS26925	COG1404	Belongs to the peptidase S8 family
CCZ36_RS26940	COG1404	Belongs to the peptidase S8 family
CCZ36_RS26950	COG4842	Belongs to the WXG100 family
CCZ36_RS26955	COG1674	ftsk spoiiie
CCZ36_RS26965	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CCZ36_RS26970	COG1185	polyribonucleotide nucleotidyltransferase activity
CCZ36_RS26975	COG0612	Peptidase, M16
CCZ36_RS26980	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CCZ36_RS27000	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
CCZ36_RS27005	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CCZ36_RS27010	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CCZ36_RS27040	COG2208	phosphoserine phosphatase activity
CCZ36_RS27040	COG2770	Histidine kinase
CCZ36_RS27045	COG2205	protein histidine kinase activity
CCZ36_RS27045	COG3850	Histidine kinase
CCZ36_RS27045	COG4999	Histidine kinase
CCZ36_RS27045	COG3437	response regulator, receiver
CCZ36_RS27055	COG1674	ftsk spoiiie
CCZ36_RS27065	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CCZ36_RS27075	COG1546	Belongs to the CinA family
CCZ36_RS27075	COG1058	Belongs to the CinA family
CCZ36_RS27080	COG1396	sequence-specific DNA binding
CCZ36_RS27085	COG0783	Belongs to the Dps family
CCZ36_RS27105	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CCZ36_RS27110	COG1201	RNA secondary structure unwinding
CCZ36_RS27115	COG1917	Cupin 2, conserved barrel domain protein
CCZ36_RS27115	COG2207	Transcriptional regulator
CCZ36_RS27150	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CCZ36_RS27180	COG0765	amino acid transport
CCZ36_RS27185	COG0765	amino acid transport
CCZ36_RS27190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CCZ36_RS27195	COG1126	abc transporter atp-binding protein
CCZ36_RS27200	COG0745	RESPONSE REGULATOR receiver
CCZ36_RS27210	COG2358	TRAP transporter, solute receptor (TAXI family
CCZ36_RS27215	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CCZ36_RS27230	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CCZ36_RS27240	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CCZ36_RS27245	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CCZ36_RS27255	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CCZ36_RS27295	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CCZ36_RS27300	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CCZ36_RS27305	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CCZ36_RS27320	COG0406	alpha-ribazole phosphatase activity
CCZ36_RS27335	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CCZ36_RS27365	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CCZ36_RS27370	COG2186	Transcriptional regulator
CCZ36_RS27375	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CCZ36_RS27400	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CCZ36_RS27405	COG4565	transcriptional regulatory protein
CCZ36_RS27410	COG3290	protein histidine kinase activity
CCZ36_RS27415	COG0372	Belongs to the citrate synthase family
CCZ36_RS27420	COG0372	Belongs to the citrate synthase family
CCZ36_RS27430	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CCZ36_RS27435	COG0612	Peptidase, M16
CCZ36_RS27450	COG1802	Transcriptional regulator
CCZ36_RS27455	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CCZ36_RS27460	COG1042	CoA-binding domain protein
CCZ36_RS27460	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CCZ36_RS27460	COG0045	succinate-CoA ligase (ADP-forming) activity
CCZ36_RS27475	COG1435	thymidine kinase activity
CCZ36_RS27500	COG0604	alcohol dehydrogenase
CCZ36_RS27500	COG3321	synthase
CCZ36_RS27505	COG0604	alcohol dehydrogenase
CCZ36_RS27510	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CCZ36_RS27530	COG3321	synthase
CCZ36_RS27530	COG0604	alcohol dehydrogenase
CCZ36_RS27535	COG1309	transcriptional regulator
CCZ36_RS27575	COG3321	synthase
CCZ36_RS27575	COG0604	alcohol dehydrogenase
CCZ36_RS27585	COG3321	synthase
CCZ36_RS27585	COG0604	alcohol dehydrogenase
CCZ36_RS27585	COG3321	synthase
CCZ36_RS27585	COG0604	alcohol dehydrogenase
CCZ36_RS27615	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CCZ36_RS27625	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CCZ36_RS27640	COG1509	lysine 2,3-aminomutase activity
CCZ36_RS27645	COG2267	carboxylic ester hydrolase activity
CCZ36_RS27675	COG1819	glycosyl
CCZ36_RS27710	COG1136	(ABC) transporter
CCZ36_RS27710	COG0577	efflux transmembrane transporter activity
CCZ36_RS27715	COG1278	Cold shock
CCZ36_RS27760	COG0745	RESPONSE REGULATOR receiver
CCZ36_RS27765	COG2205	protein histidine kinase activity
CCZ36_RS27790	COG0756	dUTP diphosphatase activity
CCZ36_RS27800	COG1136	(ABC) transporter
CCZ36_RS27830	COG0569	domain protein
CCZ36_RS27835	COG0531	amino acid
CCZ36_RS27840	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CCZ36_RS27885	COG3693	PFAM glycoside hydrolase, family 10
CCZ36_RS27900	COG1609	Transcriptional regulator
CCZ36_RS27910	COG1175	transmembrane transport
CCZ36_RS27915	COG0395	ABC-type sugar transport system, permease component
CCZ36_RS27920	COG1472	Belongs to the glycosyl hydrolase 3 family
CCZ36_RS27955	COG2843	Capsule synthesis protein
CCZ36_RS27980	COG0446	pyridine nucleotide-disulphide oxidoreductase
CCZ36_RS27990	COG3938	Belongs to the proline racemase family
CCZ36_RS27995	COG1802	Transcriptional regulator
CCZ36_RS28000	COG0006	proline dipeptidase activity
CCZ36_RS28010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CCZ36_RS28015	COG0601	transmembrane transport
CCZ36_RS28025	COG4608	Belongs to the ABC transporter superfamily
CCZ36_RS28030	COG3291	Pkd domain containing protein
CCZ36_RS28040	COG1280	lysine exporter protein (LysE YggA)
CCZ36_RS28045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CCZ36_RS28050	COG3046	protein related to deoxyribodipyrimidine photolyase
CCZ36_RS28080	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CCZ36_RS28085	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CCZ36_RS28095	COG0586	Pfam SNARE associated Golgi protein
CCZ36_RS28100	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CCZ36_RS28105	COG1349	DNA-binding transcription factor activity
CCZ36_RS28110	COG1799	cell septum assembly
CCZ36_RS28140	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CCZ36_RS28150	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CCZ36_RS28155	COG0531	amino acid
CCZ36_RS28165	COG1024	Enoyl-CoA hydratase
CCZ36_RS28200	COG1960	acyl-CoA dehydrogenase activity
CCZ36_RS28215	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CCZ36_RS28215	COG2111	Na H antiporter
CCZ36_RS28220	COG1006	Multisubunit Na H antiporter MnhC subunit
CCZ36_RS28225	COG0651	ATP synthesis coupled electron transport
CCZ36_RS28240	COG1320	monovalent cation:proton antiporter activity
CCZ36_RS28255	COG0297	glycogen (starch) synthase activity
CCZ36_RS28260	COG0489	protein tyrosine kinase activity
CCZ36_RS28295	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CCZ36_RS28300	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CCZ36_RS28340	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CCZ36_RS28375	COG1454	alcohol dehydrogenase
CCZ36_RS28375	COG1012	belongs to the aldehyde dehydrogenase family
CCZ36_RS28395	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CCZ36_RS28395	COG1017	nitric oxide dioxygenase activity
CCZ36_RS28405	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CCZ36_RS28445	COG0589	response to stress
CCZ36_RS28450	COG4651	solute:proton antiporter activity
CCZ36_RS28450	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CCZ36_RS28460	COG0589	response to stress
CCZ36_RS28465	COG0589	response to stress
CCZ36_RS28470	COG3833	ABC-type maltose transport systems, permease component
CCZ36_RS28475	COG1175	transmembrane transport
CCZ36_RS28485	COG3250	beta-galactosidase activity
CCZ36_RS28490	COG1609	Transcriptional regulator
CCZ36_RS28495	COG1482	cell wall glycoprotein biosynthetic process
CCZ36_RS28515	COG3458	cephalosporin-C deacetylase activity
CCZ36_RS28525	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CCZ36_RS28530	COG3548	integral membrane protein
CCZ36_RS28555	COG1742	UPF0060 membrane protein
CCZ36_RS28560	COG0789	Transcriptional regulator
CCZ36_RS28575	COG0588	phosphoglycerate mutase activity
CCZ36_RS28585	COG1653	transport
CCZ36_RS28590	COG1175	transmembrane transport
CCZ36_RS28595	COG0395	ABC-type sugar transport system, permease component
CCZ36_RS28600	COG1940	carbohydrate kinase activity
CCZ36_RS28605	COG4213	ABC transporter substrate-binding protein
CCZ36_RS28615	COG4214	carbohydrate transport
CCZ36_RS28620	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CCZ36_RS28625	COG0531	amino acid
CCZ36_RS28630	COG1881	PFAM PEBP family protein
CCZ36_RS28640	COG0589	response to stress
CCZ36_RS28650	COG2770	Histidine kinase
CCZ36_RS28650	COG2208	phosphoserine phosphatase activity
CCZ36_RS28685	COG1316	TRANSCRIPTIONal
CCZ36_RS28700	COG0438	transferase activity, transferring glycosyl groups
CCZ36_RS28710	COG0438	transferase activity, transferring glycosyl groups
CCZ36_RS28720	COG1250	3-hydroxyacyl-CoA dehydrogenase
CCZ36_RS28720	COG1024	Enoyl-CoA hydratase
CCZ36_RS28725	COG0183	Belongs to the thiolase family
CCZ36_RS28750	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CCZ36_RS28755	COG0446	pyridine nucleotide-disulphide oxidoreductase
CCZ36_RS28765	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CCZ36_RS28770	COG3253	May function as heme-dependent peroxidase
CCZ36_RS28785	COG3220	belongs to the UPF0276 family
CCZ36_RS28800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CCZ36_RS28805	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CCZ36_RS28815	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CCZ36_RS28820	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CCZ36_RS28825	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CCZ36_RS28855	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CCZ36_RS28865	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CCZ36_RS28870	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CCZ36_RS28885	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CCZ36_RS28920	COG0726	polysaccharide deacetylase
CCZ36_RS28950	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CCZ36_RS28955	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CCZ36_RS28995	COG1278	Cold shock
CCZ36_RS29000	COG0513	Belongs to the DEAD box helicase family
CCZ36_RS29035	COG1063	alcohol dehydrogenase
CCZ36_RS29040	COG0156	8-amino-7-oxononanoate synthase activity
CCZ36_RS29045	COG0583	DNA-binding transcription factor activity
CCZ36_RS29050	COG0346	lactoylglutathione lyase activity
CCZ36_RS29055	COG1072	(Pantothenic acid kinase))
CCZ36_RS29100	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CCZ36_RS29105	COG0583	DNA-binding transcription factor activity
CCZ36_RS29145	COG1175	transmembrane transport
CCZ36_RS29180	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CCZ36_RS29190	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CCZ36_RS29195	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CCZ36_RS29215	COG0529	Catalyzes the synthesis of activated sulfate
CCZ36_RS29220	COG0175	sulfate reduction
CCZ36_RS29245	COG1960	acyl-CoA dehydrogenase activity
CCZ36_RS29265	COG1250	3-hydroxyacyl-CoA dehydrogenase
CCZ36_RS29270	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CCZ36_RS29275	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CCZ36_RS29280	COG0583	DNA-binding transcription factor activity
CCZ36_RS29335	COG1162	GTPase activity
CCZ36_RS29355	COG1404	Belongs to the peptidase S8 family
CCZ36_RS29365	COG0028	Belongs to the TPP enzyme family
CCZ36_RS29385	COG1802	Transcriptional regulator
CCZ36_RS29410	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CCZ36_RS29415	COG2252	PERMEase
CCZ36_RS29420	COG3608	succinylglutamate desuccinylase aspartoacylase
CCZ36_RS29420	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CCZ36_RS29465	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CCZ36_RS29495	COG0435	Glutathione S-transferase
CCZ36_RS29505	COG1595	DNA-templated transcription, initiation
CCZ36_RS29525	COG2197	response regulator
CCZ36_RS29530	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CCZ36_RS29535	COG0318	PFAM AMP-dependent synthetase and ligase
CCZ36_RS29555	COG3960	tartronate-semialdehyde synthase activity
CCZ36_RS29560	COG2770	Histidine kinase
CCZ36_RS29560	COG2208	phosphoserine phosphatase activity
CCZ36_RS29565	COG0596	Alpha beta hydrolase
CCZ36_RS29570	COG0753	catalase activity
CCZ36_RS29575	COG2084	Dehydrogenase
CCZ36_RS29580	COG3622	Belongs to the hyi family
CCZ36_RS29600	COG1175	transmembrane transport
CCZ36_RS29605	COG1653	transport
CCZ36_RS29610	COG2188	Transcriptional regulator
CCZ36_RS29615	COG2706	6-phosphogluconolactonase activity
CCZ36_RS29635	COG2351	hydroxyisourate hydrolase activity
CCZ36_RS29645	COG2233	PERMEase
CCZ36_RS29655	COG2233	PERMEase
CCZ36_RS29700	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CCZ36_RS29705	COG0746	molybdenum cofactor guanylyltransferase activity
CCZ36_RS29715	COG2197	response regulator
CCZ36_RS29735	COG1414	Transcriptional regulator
CCZ36_RS29740	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CCZ36_RS29745	COG4266	Belongs to the allantoicase family
CCZ36_RS29750	COG0656	L-ascorbic acid biosynthetic process
CCZ36_RS29775	COG2197	response regulator
CCZ36_RS29785	COG0673	inositol 2-dehydrogenase activity
CCZ36_RS29790	COG2188	Transcriptional regulator
CCZ36_RS29805	COG1129	ABC transporter
CCZ36_RS29810	COG1940	carbohydrate kinase activity
CCZ36_RS29820	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CCZ36_RS29825	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CCZ36_RS29840	COG1028	Short-chain dehydrogenase reductase Sdr
CCZ36_RS29850	COG1126	abc transporter atp-binding protein
CCZ36_RS29855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CCZ36_RS29860	COG0765	amino acid transport
CCZ36_RS29865	COG0765	amino acid transport
CCZ36_RS29890	COG0405	Gamma-glutamyltransferase
CCZ36_RS29925	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CCZ36_RS29930	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CCZ36_RS29940	COG1953	Uracil, thiamine, allantoin
CCZ36_RS29970	COG2838	Isocitrate dehydrogenase
CCZ36_RS29985	COG0095	Lipoate-protein ligase
CCZ36_RS30015	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CCZ36_RS30035	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CCZ36_RS30070	COG0483	inositol monophosphate 1-phosphatase activity
CCZ36_RS30090	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CCZ36_RS30125	COG1028	Short-chain dehydrogenase reductase Sdr
CCZ36_RS30165	COG1929	Belongs to the glycerate kinase type-1 family
CCZ36_RS30185	COG0559	Belongs to the binding-protein-dependent transport system permease family
CCZ36_RS30215	COG0688	phosphatidylethanolamine metabolic process
CCZ36_RS30230	COG2301	Belongs to the HpcH HpaI aldolase family
CCZ36_RS30235	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CCZ36_RS30235	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CCZ36_RS30240	COG0604	alcohol dehydrogenase
CCZ36_RS30260	COG1250	3-hydroxyacyl-CoA dehydrogenase
CCZ36_RS30275	COG0596	Alpha beta hydrolase
CCZ36_RS30300	COG0583	DNA-binding transcription factor activity
CCZ36_RS30305	COG0667	Aldo Keto reductase
CCZ36_RS30320	COG2362	D-Aminopeptidase
CCZ36_RS30325	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CCZ36_RS30335	COG1619	proteins homologs of microcin C7 resistance protein MccF
CCZ36_RS30410	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CCZ36_RS30410	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CCZ36_RS30420	COG2154	pterin-4-alpha-carbinolamine dehydratase
CCZ36_RS30425	COG0583	DNA-binding transcription factor activity
CCZ36_RS30430	COG0702	epimerase
CCZ36_RS30440	COG4106	trans-aconitate 2-methyltransferase activity
CCZ36_RS30450	COG0656	L-ascorbic acid biosynthetic process
CCZ36_RS30475	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CCZ36_RS30480	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CCZ36_RS30490	COG1129	ABC transporter
CCZ36_RS30495	COG1172	Belongs to the binding-protein-dependent transport system permease family
CCZ36_RS30500	COG1879	ABC-type sugar transport system periplasmic component
CCZ36_RS30505	COG0673	inositol 2-dehydrogenase activity
CCZ36_RS30525	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CCZ36_RS30600	COG1129	ABC transporter
CCZ36_RS30610	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CCZ36_RS30615	COG1869	D-ribose catabolic process
CCZ36_RS30625	COG2205	protein histidine kinase activity
CCZ36_RS30630	COG0745	RESPONSE REGULATOR receiver
CCZ36_RS30640	COG1376	ErfK ybiS ycfS ynhG family protein
CCZ36_RS30650	COG0714	Associated with various cellular activities
CCZ36_RS30665	COG3568	Endonuclease Exonuclease Phosphatase
CCZ36_RS30680	COG5002	protein histidine kinase activity
CCZ36_RS30715	COG1012	belongs to the aldehyde dehydrogenase family
CCZ36_RS30725	COG4175	Glycine betaine
CCZ36_RS30725	COG0517	IMP dehydrogenase activity
CCZ36_RS30730	COG4176	ABC-type proline glycine betaine transport system permease component
CCZ36_RS30740	COG2124	cytochrome p450
CCZ36_RS30785	COG1940	carbohydrate kinase activity
CCZ36_RS30810	COG1846	Transcriptional regulator
CCZ36_RS30835	COG2124	cytochrome p450
CCZ36_RS30840	COG1486	melibiose metabolic process
CCZ36_RS30870	COG3012	SEC-C Motif Domain Protein
CCZ36_RS30890	COG1960	acyl-CoA dehydrogenase activity
CCZ36_RS30935	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CCZ36_RS31000	COG2326	polyphosphate kinase activity
CCZ36_RS31005	COG1793	dna ligase
CCZ36_RS31055	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CCZ36_RS31060	COG0596	Alpha beta hydrolase
CCZ36_RS31070	COG0488	(ABC) transporter
CCZ36_RS31095	COG1515	deoxyribonuclease V activity
CCZ36_RS31105	COG3268	Saccharopine dehydrogenase
CCZ36_RS31110	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CCZ36_RS31115	COG1960	acyl-CoA dehydrogenase activity
CCZ36_RS31120	COG0183	Belongs to the thiolase family
CCZ36_RS31125	COG1250	3-hydroxyacyl-CoA dehydrogenase
CCZ36_RS31125	COG1024	Enoyl-CoA hydratase
CCZ36_RS31130	COG0789	Transcriptional regulator
CCZ36_RS31175	COG0488	(ABC) transporter
CCZ36_RS31180	COG2183	response to ionizing radiation
CCZ36_RS31190	COG4977	sequence-specific DNA binding
CCZ36_RS31200	COG1024	Enoyl-CoA hydratase
CCZ36_RS31215	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CCZ36_RS31240	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CCZ36_RS31260	COG1388	LysM domain
CCZ36_RS31260	COG1134	teichoic acid transport
CCZ36_RS31265	COG1562	ergosterol biosynthetic process
CCZ36_RS31275	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CCZ36_RS31285	COG1657	PFAM Prenyltransferase squalene oxidase
CCZ36_RS31315	COG0739	heme binding
CCZ36_RS31320	COG2755	lipolytic protein G-D-S-L family
CCZ36_RS31330	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CCZ36_RS31370	COG3467	pyridoxamine 5'-phosphate
CCZ36_RS31430	COG1609	Transcriptional regulator
CCZ36_RS31435	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CCZ36_RS31445	COG1116	anion transmembrane transporter activity
CCZ36_RS31465	COG3507	Belongs to the glycosyl hydrolase 43 family
CCZ36_RS31475	COG3958	Transketolase
CCZ36_RS31480	COG3959	Transketolase, thiamine diphosphate binding domain
CCZ36_RS31515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CCZ36_RS31520	COG3511	phospholipase C
CCZ36_RS31590	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CCZ36_RS31640	COG2409	Drug exporters of the RND superfamily
CCZ36_RS31690	COG1233	COG1233 Phytoene dehydrogenase and related
CCZ36_RS31715	COG0640	Transcriptional regulator
CCZ36_RS31720	COG2217	Heavy metal translocating P-type atpase
CCZ36_RS31725	COG1120	ATPase activity
CCZ36_RS31730	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CCZ36_RS31755	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CCZ36_RS31765	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CCZ36_RS31785	COG2837	iron assimilation
CCZ36_RS31790	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CCZ36_RS31805	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CCZ36_RS31835	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CCZ36_RS31840	COG2723	6-phospho-beta-galactosidase activity
CCZ36_RS31845	COG0395	ABC-type sugar transport system, permease component
CCZ36_RS31865	COG0494	nUDIX hydrolase
CCZ36_RS31930	COG4251	negative regulation of phosphorylation
CCZ36_RS31935	COG2201	protein-glutamate methylesterase activity
CCZ36_RS31940	COG1191	sigma factor activity
CCZ36_RS31980	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CCZ36_RS32005	COG3275	phosphorelay sensor kinase activity
CCZ36_RS32075	COG0583	DNA-binding transcription factor activity
CCZ36_RS32085	COG1053	succinate dehydrogenase
CCZ36_RS32090	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CCZ36_RS32100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CCZ36_RS32110	COG3360	Dodecin
CCZ36_RS32115	COG2182	Extracellular solute-binding protein
CCZ36_RS32130	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
CCZ36_RS32135	COG0121	glutamine amidotransferase
CCZ36_RS32140	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CCZ36_RS32145	COG3572	ergothioneine biosynthetic process
CCZ36_RS32160	COG1609	Transcriptional regulator
CCZ36_RS32170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CCZ36_RS32175	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CCZ36_RS32190	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CCZ36_RS32200	COG0477	Major facilitator Superfamily
CCZ36_RS32225	COG0714	Associated with various cellular activities
CCZ36_RS32250	COG1357	PFAM Pentapeptide repeats (8 copies)
CCZ36_RS32260	COG2045	Belongs to the ComB family
CCZ36_RS32270	COG1834	amidinotransferase
CCZ36_RS32280	COG1228	amidohydrolase
CCZ36_RS32290	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CCZ36_RS32305	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CCZ36_RS32450	COG1233	COG1233 Phytoene dehydrogenase and related
CCZ36_RS32490	COG1120	ATPase activity
CCZ36_RS32505	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CCZ36_RS32515	COG0254	rRNA binding
CCZ36_RS32520	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CCZ36_RS32525	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CCZ36_RS32530	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CCZ36_RS32545	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CCZ36_RS32550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CCZ36_RS32555	COG1120	ATPase activity
CCZ36_RS32625	COG2304	oxidoreductase activity
CCZ36_RS32645	COG0438	transferase activity, transferring glycosyl groups
CCZ36_RS32650	COG0726	polysaccharide deacetylase
CCZ36_RS32670	COG0438	transferase activity, transferring glycosyl groups
CCZ36_RS32720	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CCZ36_RS32740	COG1960	acyl-CoA dehydrogenase activity
CCZ36_RS32745	COG1960	acyl-CoA dehydrogenase activity
CCZ36_RS32760	COG0601	transmembrane transport
CCZ36_RS32770	COG0444	Belongs to the ABC transporter superfamily
CCZ36_RS32845	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CCZ36_RS32845	COG1796	DNA polymerase
CCZ36_RS32920	COG1278	Cold shock
CCZ36_RS32935	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CCZ36_RS32940	COG0693	protein deglycase activity
CCZ36_RS32955	COG2375	cellular response to nickel ion
CCZ36_RS32980	COG1063	alcohol dehydrogenase
CCZ36_RS32990	COG1175	transmembrane transport
CCZ36_RS33020	COG0789	Transcriptional regulator
CCZ36_RS33025	COG1960	acyl-CoA dehydrogenase activity
CCZ36_RS33035	COG1408	metallophosphoesterase
CCZ36_RS33075	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
CCZ36_RS33145	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CCZ36_RS33150	COG3239	Fatty acid desaturase
CCZ36_RS33180	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CCZ36_RS33185	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CCZ36_RS33190	COG0640	Transcriptional regulator
CCZ36_RS33205	COG2018	Roadblock/LC7 domain
CCZ36_RS33255	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CCZ36_RS33260	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CCZ36_RS33275	COG2340	Cysteine-rich secretory protein family
CCZ36_RS33335	COG0009	L-threonylcarbamoyladenylate synthase
CCZ36_RS33380	COG2318	DinB family
CCZ36_RS33395	COG1609	Transcriptional regulator
CCZ36_RS33405	COG1175	transmembrane transport
CCZ36_RS33410	COG0395	ABC-type sugar transport system, permease component
CCZ36_RS33415	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CCZ36_RS33430	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CCZ36_RS33435	COG1028	Short-chain dehydrogenase reductase Sdr
CCZ36_RS33445	COG0714	Associated with various cellular activities
CCZ36_RS33450	COG3552	Protein containing von Willebrand factor type A (VWA) domain
CCZ36_RS33475	COG2205	protein histidine kinase activity
CCZ36_RS33480	COG0745	RESPONSE REGULATOR receiver
CCZ36_RS33495	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CCZ36_RS33500	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CCZ36_RS33515	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CCZ36_RS33600	COG4214	carbohydrate transport
CCZ36_RS33610	COG4213	ABC transporter substrate-binding protein
CCZ36_RS33620	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CCZ36_RS33635	COG1070	Carbohydrate kinase
CCZ36_RS33675	COG1309	transcriptional regulator
CCZ36_RS33680	COG1309	transcriptional regulator
CCZ36_RS33685	COG1028	Short-chain dehydrogenase reductase Sdr
CCZ36_RS33690	COG3321	synthase
CCZ36_RS33690	COG0604	alcohol dehydrogenase
CCZ36_RS33770	COG0142	geranyltranstransferase activity
CCZ36_RS33840	COG0110	maltose O-acetyltransferase activity
CCZ36_RS33845	COG1309	transcriptional regulator
CCZ36_RS33870	COG2124	cytochrome p450
CCZ36_RS33890	COG2226	methyltransferase
CCZ36_RS34060	COG1595	DNA-templated transcription, initiation
CCZ36_RS34195	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CCZ36_RS34200	COG0494	nUDIX hydrolase
CCZ36_RS34250	COG0142	geranyltranstransferase activity
CCZ36_RS34270	COG0587	DNA-directed DNA polymerase activity
CCZ36_RS34515	COG4585	Histidine kinase
CCZ36_RS34530	COG2197	response regulator
CCZ36_RS34600	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP