locus-tag	class	description
FNV65_RS00075	COG1278	Cold shock
FNV65_RS00160	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FNV65_RS00175	COG2197	response regulator
FNV65_RS00220	COG0596	Alpha beta hydrolase
FNV65_RS00275	COG0596	Alpha beta hydrolase
FNV65_RS00335	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FNV65_RS00545	COG1959	2 iron, 2 sulfur cluster binding
FNV65_RS00590	COG0477	Major facilitator Superfamily
FNV65_RS00700	COG2124	cytochrome p450
FNV65_RS00755	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FNV65_RS00770	COG1733	regulation of RNA biosynthetic process
FNV65_RS00775	COG0604	alcohol dehydrogenase
FNV65_RS00790	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FNV65_RS00890	COG0659	secondary active sulfate transmembrane transporter activity
FNV65_RS00900	COG2824	Alkylphosphonate utilization operon protein PhnA
FNV65_RS00940	COG1136	(ABC) transporter
FNV65_RS00980	COG0456	acetyltransferase
FNV65_RS01000	COG0702	epimerase
FNV65_RS01060	COG2267	carboxylic ester hydrolase activity
FNV65_RS01065	COG2197	response regulator
FNV65_RS01115	COG2130	NADP-dependent
FNV65_RS01185	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS01205	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FNV65_RS01235	COG0671	phosphoesterase, PA-phosphatase related
FNV65_RS01250	COG2814	Major facilitator Superfamily
FNV65_RS01270	COG0726	polysaccharide deacetylase
FNV65_RS01290	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FNV65_RS01295	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FNV65_RS01335	COG2267	carboxylic ester hydrolase activity
FNV65_RS01400	COG4585	Histidine kinase
FNV65_RS01405	COG2197	response regulator
FNV65_RS01425	COG1278	Cold shock
FNV65_RS01440	COG0596	Alpha beta hydrolase
FNV65_RS01445	COG2045	Belongs to the ComB family
FNV65_RS01485	COG3293	Transposase
FNV65_RS01630	COG3629	intracellular signal transduction
FNV65_RS01630	COG3903	Transcriptional regulator
FNV65_RS01650	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FNV65_RS01675	COG0583	DNA-binding transcription factor activity
FNV65_RS01685	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FNV65_RS01715	COG0640	Transcriptional regulator
FNV65_RS01745	COG1609	Transcriptional regulator
FNV65_RS01750	COG2723	6-phospho-beta-galactosidase activity
FNV65_RS01765	COG3250	beta-galactosidase activity
FNV65_RS01770	COG3250	beta-galactosidase activity
FNV65_RS01785	COG3507	Belongs to the glycosyl hydrolase 43 family
FNV65_RS01795	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FNV65_RS01805	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS01835	COG3250	beta-galactosidase activity
FNV65_RS01870	COG3290	protein histidine kinase activity
FNV65_RS01895	COG1131	(ABC) transporter
FNV65_RS01905	COG1595	DNA-templated transcription, initiation
FNV65_RS01990	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FNV65_RS02005	COG1309	transcriptional regulator
FNV65_RS02070	COG0745	RESPONSE REGULATOR receiver
FNV65_RS02075	COG2205	protein histidine kinase activity
FNV65_RS02105	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FNV65_RS02130	COG4585	Histidine kinase
FNV65_RS02135	COG2197	response regulator
FNV65_RS02140	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS02145	COG0567	Dehydrogenase, E1 component
FNV65_RS02145	COG0508	dehydrogenase complex catalyzes the overall conversion of
FNV65_RS02165	COG1090	epimerase
FNV65_RS02170	COG1595	DNA-templated transcription, initiation
FNV65_RS02190	COG1250	3-hydroxyacyl-CoA dehydrogenase
FNV65_RS02200	COG1960	acyl-CoA dehydrogenase activity
FNV65_RS02230	COG0778	Nitroreductase
FNV65_RS02235	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FNV65_RS02240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FNV65_RS02270	COG1063	alcohol dehydrogenase
FNV65_RS02275	COG2124	cytochrome p450
FNV65_RS02275	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FNV65_RS02315	COG1309	transcriptional regulator
FNV65_RS02330	COG1660	Displays ATPase and GTPase activities
FNV65_RS02345	COG0596	Alpha beta hydrolase
FNV65_RS02535	COG2890	protein-(glutamine-N5) methyltransferase activity
FNV65_RS02555	COG0069	glutamate synthase activity
FNV65_RS02560	COG0028	Belongs to the TPP enzyme family
FNV65_RS02565	COG0596	Alpha beta hydrolase
FNV65_RS02575	COG1366	Belongs to the anti-sigma-factor antagonist family
FNV65_RS02585	COG1024	Enoyl-CoA hydratase
FNV65_RS02620	COG1120	ATPase activity
FNV65_RS02625	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FNV65_RS02635	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FNV65_RS02640	COG1535	isochorismatase
FNV65_RS02640	COG3433	isochorismatase activity
FNV65_RS02660	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FNV65_RS02715	COG2226	methyltransferase
FNV65_RS02755	COG1522	sequence-specific DNA binding
FNV65_RS02770	COG0667	Aldo Keto reductase
FNV65_RS02810	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS02825	COG3537	Alpha-1,2-mannosidase
FNV65_RS02830	COG0667	Aldo Keto reductase
FNV65_RS02835	COG1309	transcriptional regulator
FNV65_RS02840	COG3619	membrane
FNV65_RS02845	COG0583	DNA-binding transcription factor activity
FNV65_RS02850	COG3876	Protein conserved in bacteria
FNV65_RS02865	COG1175	transmembrane transport
FNV65_RS02870	COG0395	ABC-type sugar transport system, permease component
FNV65_RS02885	COG1902	pentaerythritol trinitrate reductase activity
FNV65_RS02905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNV65_RS02920	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FNV65_RS02930	COG1073	alpha beta
FNV65_RS02935	COG1024	Enoyl-CoA hydratase
FNV65_RS02945	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FNV65_RS02970	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS02990	COG1309	transcriptional regulator
FNV65_RS02995	COG0655	NAD(P)H dehydrogenase (quinone) activity
FNV65_RS03005	COG1733	regulation of RNA biosynthetic process
FNV65_RS03020	COG1309	transcriptional regulator
FNV65_RS03040	COG1960	acyl-CoA dehydrogenase activity
FNV65_RS03045	COG1960	acyl-CoA dehydrogenase activity
FNV65_RS03055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV65_RS03065	COG1960	acyl-CoA dehydrogenase activity
FNV65_RS03075	COG1024	Enoyl-CoA hydratase
FNV65_RS03080	COG0318	PFAM AMP-dependent synthetase and ligase
FNV65_RS03085	COG1309	transcriptional regulator
FNV65_RS03090	COG0667	Aldo Keto reductase
FNV65_RS03095	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FNV65_RS03120	COG0800	Aldolase
FNV65_RS03130	COG4948	Mandelate Racemase Muconate Lactonizing
FNV65_RS03150	COG0395	ABC-type sugar transport system, permease component
FNV65_RS03155	COG1175	transmembrane transport
FNV65_RS03165	COG3345	alpha-galactosidase
FNV65_RS03170	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FNV65_RS03200	COG1309	transcriptional regulator
FNV65_RS03230	COG0366	Alpha amylase catalytic
FNV65_RS03240	COG2207	Transcriptional regulator
FNV65_RS03245	COG2223	nitrite transmembrane transporter activity
FNV65_RS03275	COG1012	belongs to the aldehyde dehydrogenase family
FNV65_RS03305	COG1609	Transcriptional regulator
FNV65_RS03320	COG0395	ABC-type sugar transport system, permease component
FNV65_RS03375	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FNV65_RS03395	COG0488	(ABC) transporter
FNV65_RS03400	COG0488	(ABC) transporter
FNV65_RS03455	COG1764	response to oxidative stress
FNV65_RS03495	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FNV65_RS03525	COG0477	Major facilitator Superfamily
FNV65_RS03565	COG3345	alpha-galactosidase
FNV65_RS03585	COG2186	Transcriptional regulator
FNV65_RS03595	COG1175	transmembrane transport
FNV65_RS03600	COG0395	ABC-type sugar transport system, permease component
FNV65_RS03615	COG3618	amidohydrolase
FNV65_RS03620	COG1063	alcohol dehydrogenase
FNV65_RS03625	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS03630	COG0800	Aldolase
FNV65_RS03645	COG0179	Fumarylacetoacetate (FAA) hydrolase
FNV65_RS03655	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS03665	COG0247	lactate metabolic process
FNV65_RS03675	COG3693	PFAM glycoside hydrolase, family 10
FNV65_RS03705	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FNV65_RS03715	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNV65_RS03720	COG0800	Aldolase
FNV65_RS03725	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS03730	COG1063	alcohol dehydrogenase
FNV65_RS03740	COG3618	amidohydrolase
FNV65_RS03745	COG4948	Mandelate Racemase Muconate Lactonizing
FNV65_RS03750	COG1172	Belongs to the binding-protein-dependent transport system permease family
FNV65_RS03755	COG1129	ABC transporter
FNV65_RS03770	COG2755	lipolytic protein G-D-S-L family
FNV65_RS03785	COG3507	Belongs to the glycosyl hydrolase 43 family
FNV65_RS03805	COG0395	ABC-type sugar transport system, permease component
FNV65_RS03810	COG4209	transmembrane transport
FNV65_RS03835	COG1501	Belongs to the glycosyl hydrolase 31 family
FNV65_RS03870	COG0519	Catalyzes the synthesis of GMP from XMP
FNV65_RS03870	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FNV65_RS03885	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FNV65_RS03900	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS03905	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS03910	COG2188	Transcriptional regulator
FNV65_RS03920	COG1175	transmembrane transport
FNV65_RS03925	COG0395	ABC-type sugar transport system, permease component
FNV65_RS03995	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FNV65_RS04005	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FNV65_RS04045	COG3469	chitinase activity
FNV65_RS04060	COG3903	Transcriptional regulator
FNV65_RS04060	COG3629	intracellular signal transduction
FNV65_RS04100	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS04105	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS04115	COG1764	response to oxidative stress
FNV65_RS04180	COG2208	phosphoserine phosphatase activity
FNV65_RS04180	COG2770	Histidine kinase
FNV65_RS04200	COG0583	DNA-binding transcription factor activity
FNV65_RS04215	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS04240	COG0702	epimerase
FNV65_RS04250	COG2271	Major facilitator Superfamily
FNV65_RS04255	COG2755	lipolytic protein G-D-S-L family
FNV65_RS04255	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FNV65_RS04260	COG3250	beta-galactosidase activity
FNV65_RS04295	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FNV65_RS04340	COG2197	response regulator
FNV65_RS04355	COG1082	Xylose isomerase domain protein TIM barrel
FNV65_RS04365	COG1082	Xylose isomerase domain protein TIM barrel
FNV65_RS04385	COG2226	methyltransferase
FNV65_RS04390	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FNV65_RS04420	COG4213	ABC transporter substrate-binding protein
FNV65_RS04430	COG4213	ABC transporter substrate-binding protein
FNV65_RS04440	COG4214	carbohydrate transport
FNV65_RS04450	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FNV65_RS04455	COG1414	Transcriptional regulator
FNV65_RS04480	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FNV65_RS04485	COG0640	Transcriptional regulator
FNV65_RS04490	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FNV65_RS04495	COG0248	Ppx GppA phosphatase
FNV65_RS04505	COG1609	Transcriptional regulator
FNV65_RS04525	COG0395	ABC-type sugar transport system, permease component
FNV65_RS04540	COG0477	Major facilitator Superfamily
FNV65_RS04550	COG2124	cytochrome p450
FNV65_RS04625	COG1191	sigma factor activity
FNV65_RS04630	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FNV65_RS04715	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FNV65_RS04725	COG1064	alcohol dehydrogenase
FNV65_RS04755	COG0009	L-threonylcarbamoyladenylate synthase
FNV65_RS04765	COG0443	Heat shock 70 kDa protein
FNV65_RS04770	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FNV65_RS04785	COG0542	response to heat
FNV65_RS04800	COG1414	Transcriptional regulator
FNV65_RS04805	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FNV65_RS04810	COG2610	gluconate transmembrane transporter activity
FNV65_RS04815	COG4948	Mandelate Racemase Muconate Lactonizing
FNV65_RS04830	COG1136	(ABC) transporter
FNV65_RS04835	COG4585	Histidine kinase
FNV65_RS04840	COG2197	response regulator
FNV65_RS04845	COG1309	transcriptional regulator
FNV65_RS04850	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS04860	COG1595	DNA-templated transcription, initiation
FNV65_RS04870	COG2362	D-Aminopeptidase
FNV65_RS04900	COG2814	Major facilitator Superfamily
FNV65_RS04915	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FNV65_RS04920	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FNV65_RS04925	COG2186	Transcriptional regulator
FNV65_RS04945	COG5006	permease, DMT superfamily
FNV65_RS04960	COG0477	Major facilitator Superfamily
FNV65_RS05015	COG0464	growth
FNV65_RS05120	COG1846	Transcriptional regulator
FNV65_RS05120	COG1940	carbohydrate kinase activity
FNV65_RS05200	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FNV65_RS05220	COG4585	Histidine kinase
FNV65_RS05225	COG2197	response regulator
FNV65_RS05270	COG1881	PFAM PEBP family protein
FNV65_RS05285	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS05290	COG2186	Transcriptional regulator
FNV65_RS05295	COG1024	Enoyl-CoA hydratase
FNV65_RS05300	COG1960	acyl-CoA dehydrogenase activity
FNV65_RS05305	COG1960	acyl-CoA dehydrogenase activity
FNV65_RS05310	COG0318	PFAM AMP-dependent synthetase and ligase
FNV65_RS05320	COG1024	Enoyl-CoA hydratase
FNV65_RS05325	COG0183	Belongs to the thiolase family
FNV65_RS05330	COG1960	acyl-CoA dehydrogenase activity
FNV65_RS05335	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS05350	COG1024	Enoyl-CoA hydratase
FNV65_RS05355	COG1024	Enoyl-CoA hydratase
FNV65_RS05405	COG1960	acyl-CoA dehydrogenase activity
FNV65_RS05415	COG1960	acyl-CoA dehydrogenase activity
FNV65_RS05420	COG2272	Belongs to the type-B carboxylesterase lipase family
FNV65_RS05425	COG1024	Enoyl-CoA hydratase
FNV65_RS05440	COG0183	Belongs to the thiolase family
FNV65_RS05445	COG0318	PFAM AMP-dependent synthetase and ligase
FNV65_RS05465	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV65_RS05470	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FNV65_RS05475	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FNV65_RS05475	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FNV65_RS05480	COG0318	PFAM AMP-dependent synthetase and ligase
FNV65_RS05490	COG0318	PFAM AMP-dependent synthetase and ligase
FNV65_RS05500	COG1024	Enoyl-CoA hydratase
FNV65_RS05510	COG1309	transcriptional regulator
FNV65_RS05550	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNV65_RS05555	COG1012	belongs to the aldehyde dehydrogenase family
FNV65_RS05570	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS05580	COG4638	Rieske (2fe-2S)
FNV65_RS05590	COG1228	amidohydrolase
FNV65_RS05600	COG1960	acyl-CoA dehydrogenase activity
FNV65_RS05610	COG3321	synthase
FNV65_RS05610	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS05610	COG0604	alcohol dehydrogenase
FNV65_RS05620	COG1960	acyl-CoA dehydrogenase activity
FNV65_RS05655	COG0745	RESPONSE REGULATOR receiver
FNV65_RS05660	COG1846	Transcriptional regulator
FNV65_RS05665	COG1309	transcriptional regulator
FNV65_RS05670	COG4585	Histidine kinase
FNV65_RS05675	COG2197	response regulator
FNV65_RS05695	COG2814	Major facilitator Superfamily
FNV65_RS05745	COG0277	FAD linked oxidase domain protein
FNV65_RS05760	COG0366	Alpha amylase catalytic
FNV65_RS05770	COG3281	Trehalose synthase
FNV65_RS05775	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FNV65_RS05805	COG1136	(ABC) transporter
FNV65_RS05805	COG0577	efflux transmembrane transporter activity
FNV65_RS05910	COG0477	Major facilitator Superfamily
FNV65_RS05935	COG0494	nUDIX hydrolase
FNV65_RS05965	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FNV65_RS06020	COG3883	PFAM NLP P60 protein
FNV65_RS06020	COG0791	NLP P60 protein
FNV65_RS06065	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
FNV65_RS06100	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FNV65_RS06140	COG0539	negative regulation of cytoplasmic translation
FNV65_RS06155	COG4974	Belongs to the 'phage' integrase family
FNV65_RS06200	COG0531	amino acid
FNV65_RS06210	COG1181	Belongs to the D-alanine--D-alanine ligase family
FNV65_RS06230	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FNV65_RS06300	COG3189	MarR family transcriptional regulator
FNV65_RS06365	COG0396	ATPase activity
FNV65_RS06420	COG3321	synthase
FNV65_RS06420	COG4221	oxidoreductase activity
FNV65_RS06420	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS06420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FNV65_RS06425	COG2175	clavaminate synthase activity
FNV65_RS06540	COG3903	Transcriptional regulator
FNV65_RS06540	COG3629	intracellular signal transduction
FNV65_RS06630	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FNV65_RS06630	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FNV65_RS06845	COG2226	methyltransferase
FNV65_RS06900	COG3629	intracellular signal transduction
FNV65_RS06900	COG3903	Transcriptional regulator
FNV65_RS06970	COG1278	Cold shock
FNV65_RS07020	COG1484	DNA-dependent DNA replication
FNV65_RS07025	COG4584	PFAM Integrase catalytic
FNV65_RS07085	COG3345	alpha-galactosidase
FNV65_RS07090	COG0395	ABC-type sugar transport system, permease component
FNV65_RS07095	COG1175	transmembrane transport
FNV65_RS07105	COG1846	Transcriptional regulator
FNV65_RS07105	COG1940	carbohydrate kinase activity
FNV65_RS07120	COG0574	Belongs to the PEP-utilizing enzyme family
FNV65_RS07120	COG3848	Pyruvate phosphate dikinase
FNV65_RS07180	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FNV65_RS07185	COG1793	dna ligase
FNV65_RS07195	COG0539	negative regulation of cytoplasmic translation
FNV65_RS07220	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS07245	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FNV65_RS07290	COG2267	carboxylic ester hydrolase activity
FNV65_RS07390	COG2226	methyltransferase
FNV65_RS07475	COG0702	epimerase
FNV65_RS07565	COG3547	Transposase (IS116 IS110 IS902 family)
FNV65_RS07745	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FNV65_RS07775	COG1793	dna ligase
FNV65_RS07860	COG2801	Transposase and inactivated derivatives
FNV65_RS07910	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FNV65_RS07970	COG3387	PFAM Glycoside hydrolase 15-related
FNV65_RS07995	COG0492	ferredoxin-NADP+ reductase activity
FNV65_RS08015	COG2409	Drug exporters of the RND superfamily
FNV65_RS08020	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FNV65_RS08030	COG2197	response regulator
FNV65_RS08070	COG3655	Transcriptional regulator
FNV65_RS08135	COG1335	isochorismatase
FNV65_RS08145	COG3328	transposase activity
FNV65_RS08220	COG0831	urea catabolic process
FNV65_RS08220	COG0832	Belongs to the urease beta subunit family
FNV65_RS08225	COG0804	urea catabolic process
FNV65_RS08230	COG0830	nickel cation binding
FNV65_RS08235	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FNV65_RS08240	COG0829	nickel cation binding
FNV65_RS08250	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FNV65_RS08270	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FNV65_RS08320	COG1215	transferase activity, transferring glycosyl groups
FNV65_RS08335	COG0438	transferase activity, transferring glycosyl groups
FNV65_RS08340	COG0789	Transcriptional regulator
FNV65_RS08345	COG4221	oxidoreductase activity
FNV65_RS08365	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FNV65_RS08415	COG1618	nucleotide phosphatase activity, acting on free nucleotides
FNV65_RS08510	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FNV65_RS08550	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FNV65_RS08600	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FNV65_RS08705	COG2304	oxidoreductase activity
FNV65_RS08740	COG0328	RNA-DNA hybrid ribonuclease activity
FNV65_RS08795	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNV65_RS08805	COG0747	negative chemotaxis
FNV65_RS08835	COG3835	regulator
FNV65_RS08840	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FNV65_RS08840	COG2010	Cytochrome c
FNV65_RS08845	COG2080	2 iron, 2 sulfur cluster binding
FNV65_RS08870	COG0009	L-threonylcarbamoyladenylate synthase
FNV65_RS08960	COG0596	Alpha beta hydrolase
FNV65_RS08965	COG0740	serine-type endopeptidase activity
FNV65_RS08970	COG0740	serine-type endopeptidase activity
FNV65_RS08980	COG2318	DinB family
FNV65_RS08995	COG0784	Response regulator, receiver
FNV65_RS09000	COG4251	negative regulation of phosphorylation
FNV65_RS09060	COG1716	ATPase activity
FNV65_RS09060	COG1131	(ABC) transporter
FNV65_RS09060	COG0842	Transport permease protein
FNV65_RS09080	COG2207	Transcriptional regulator
FNV65_RS09090	COG0667	Aldo Keto reductase
FNV65_RS09095	COG0583	DNA-binding transcription factor activity
FNV65_RS09110	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FNV65_RS09115	COG0346	lactoylglutathione lyase activity
FNV65_RS09120	COG0671	phosphoesterase, PA-phosphatase related
FNV65_RS09130	COG0412	Dienelactone hydrolase
FNV65_RS09135	COG0667	Aldo Keto reductase
FNV65_RS09145	COG1012	belongs to the aldehyde dehydrogenase family
FNV65_RS09150	COG4941	Belongs to the sigma-70 factor family
FNV65_RS09165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV65_RS09175	COG0431	NADPH-dependent FMN reductase
FNV65_RS09195	COG0702	epimerase
FNV65_RS09280	COG0531	amino acid
FNV65_RS09285	COG1940	carbohydrate kinase activity
FNV65_RS09290	COG3250	beta-galactosidase activity
FNV65_RS09310	COG3345	alpha-galactosidase
FNV65_RS09315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNV65_RS09335	COG0667	Aldo Keto reductase
FNV65_RS09365	COG0367	asparagine synthase
FNV65_RS09370	COG0069	glutamate synthase activity
FNV65_RS09375	COG2235	arginine
FNV65_RS09390	COG0673	inositol 2-dehydrogenase activity
FNV65_RS09395	COG3511	phospholipase C
FNV65_RS09430	COG1404	Belongs to the peptidase S8 family
FNV65_RS09445	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FNV65_RS09445	COG1672	PFAM Archaeal ATPase
FNV65_RS09485	COG0318	PFAM AMP-dependent synthetase and ligase
FNV65_RS09490	COG2366	antibiotic biosynthetic process
FNV65_RS09500	COG2070	2-Nitropropane dioxygenase
FNV65_RS09510	COG0515	serine threonine protein kinase
FNV65_RS09520	COG1960	acyl-CoA dehydrogenase activity
FNV65_RS09545	COG4172	Belongs to the ABC transporter superfamily
FNV65_RS09550	COG4171	peptide transport system, permease
FNV65_RS09560	COG0747	negative chemotaxis
FNV65_RS09575	COG0019	diaminopimelate decarboxylase activity
FNV65_RS09580	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FNV65_RS09585	COG0534	Mate efflux family protein
FNV65_RS09590	COG1609	Transcriptional regulator
FNV65_RS09605	COG2188	Transcriptional regulator
FNV65_RS09615	COG3962	Belongs to the TPP enzyme family
FNV65_RS09620	COG3718	enzyme involved in inositol metabolism
FNV65_RS09630	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNV65_RS09660	COG0028	Belongs to the TPP enzyme family
FNV65_RS09665	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS09670	COG2072	flavoprotein involved in K transport
FNV65_RS09675	COG4638	Rieske (2fe-2S)
FNV65_RS09680	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS09685	COG3386	PFAM SMP-30 Gluconolaconase
FNV65_RS09690	COG1960	acyl-CoA dehydrogenase activity
FNV65_RS09695	COG1960	acyl-CoA dehydrogenase activity
FNV65_RS09705	COG1960	acyl-CoA dehydrogenase activity
FNV65_RS09710	COG0604	alcohol dehydrogenase
FNV65_RS09720	COG0318	PFAM AMP-dependent synthetase and ligase
FNV65_RS09725	COG0427	acetyl-CoA hydrolase
FNV65_RS09755	COG2186	Transcriptional regulator
FNV65_RS09760	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS09770	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNV65_RS09775	COG1960	acyl-CoA dehydrogenase activity
FNV65_RS09800	COG0604	alcohol dehydrogenase
FNV65_RS09800	COG3321	synthase
FNV65_RS09800	COG4221	oxidoreductase activity
FNV65_RS09800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FNV65_RS09835	COG1309	transcriptional regulator
FNV65_RS09845	COG1335	isochorismatase
FNV65_RS09920	COG2072	flavoprotein involved in K transport
FNV65_RS09945	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FNV65_RS09950	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FNV65_RS09955	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FNV65_RS09965	COG0531	amino acid
FNV65_RS10015	COG3321	synthase
FNV65_RS10015	COG0604	alcohol dehydrogenase
FNV65_RS10025	COG1073	alpha beta
FNV65_RS10070	COG0363	glucosamine-6-phosphate deaminase activity
FNV65_RS10075	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FNV65_RS10095	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FNV65_RS10100	COG2376	Dihydroxyacetone kinase
FNV65_RS10105	COG1461	Dihydroxyacetone kinase
FNV65_RS10120	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS10150	COG1902	pentaerythritol trinitrate reductase activity
FNV65_RS10150	COG0446	pyridine nucleotide-disulphide oxidoreductase
FNV65_RS10155	COG2890	protein-(glutamine-N5) methyltransferase activity
FNV65_RS10170	COG3321	synthase
FNV65_RS10170	COG0604	alcohol dehydrogenase
FNV65_RS10175	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FNV65_RS10200	COG3458	cephalosporin-C deacetylase activity
FNV65_RS10210	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FNV65_RS10215	COG2188	Transcriptional regulator
FNV65_RS10225	COG2226	methyltransferase
FNV65_RS10230	COG0366	Alpha amylase catalytic
FNV65_RS10235	COG2267	carboxylic ester hydrolase activity
FNV65_RS10245	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS10250	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FNV65_RS10290	COG0179	Fumarylacetoacetate (FAA) hydrolase
FNV65_RS10305	COG4941	Belongs to the sigma-70 factor family
FNV65_RS10315	COG3795	YCII-related domain
FNV65_RS10325	COG0346	lactoylglutathione lyase activity
FNV65_RS10330	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS10340	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FNV65_RS10345	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FNV65_RS10350	COG1686	Belongs to the peptidase S11 family
FNV65_RS10355	COG5650	phosphatidylinositol metabolic process
FNV65_RS10365	COG2066	Belongs to the glutaminase family
FNV65_RS10380	COG1113	amino acid transport
FNV65_RS10390	COG1968	undecaprenyl-diphosphatase activity
FNV65_RS10395	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FNV65_RS10400	COG1993	acr, cog1993
FNV65_RS10405	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FNV65_RS10430	COG1175	transmembrane transport
FNV65_RS10435	COG0395	ABC-type sugar transport system, permease component
FNV65_RS10455	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FNV65_RS10470	COG1960	acyl-CoA dehydrogenase activity
FNV65_RS10480	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FNV65_RS10520	COG1215	transferase activity, transferring glycosyl groups
FNV65_RS10535	COG0633	Ferredoxin
FNV65_RS10535	COG3217	Mosc domain protein beta barrel domain protein
FNV65_RS10555	COG1349	DNA-binding transcription factor activity
FNV65_RS10580	COG0577	efflux transmembrane transporter activity
FNV65_RS10585	COG1136	(ABC) transporter
FNV65_RS10610	COG1940	carbohydrate kinase activity
FNV65_RS10620	COG2813	Specifically methylates the guanine in position
FNV65_RS10645	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FNV65_RS10650	COG1349	DNA-binding transcription factor activity
FNV65_RS10655	COG3537	Alpha-1,2-mannosidase
FNV65_RS10665	COG1174	glycine betaine transport
FNV65_RS10685	COG2018	Roadblock/LC7 domain
FNV65_RS10715	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FNV65_RS10715	COG3320	Male sterility
FNV65_RS10720	COG0604	alcohol dehydrogenase
FNV65_RS10720	COG3321	synthase
FNV65_RS10725	COG0318	PFAM AMP-dependent synthetase and ligase
FNV65_RS10735	COG0596	Alpha beta hydrolase
FNV65_RS10740	COG4565	transcriptional regulatory protein
FNV65_RS10745	COG3290	protein histidine kinase activity
FNV65_RS10755	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNV65_RS10785	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS10790	COG1271	oxidase subunit
FNV65_RS10845	COG3387	PFAM Glycoside hydrolase 15-related
FNV65_RS10865	COG2223	nitrite transmembrane transporter activity
FNV65_RS10890	COG2197	response regulator
FNV65_RS10895	COG4585	Histidine kinase
FNV65_RS10910	COG0445	tRNA wobble uridine modification
FNV65_RS10920	COG1660	Displays ATPase and GTPase activities
FNV65_RS10950	COG0395	ABC-type sugar transport system, permease component
FNV65_RS10965	COG3345	alpha-galactosidase
FNV65_RS10995	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FNV65_RS11020	COG0204	Acyl-transferase
FNV65_RS11050	COG0584	glycerophosphoryl diester phosphodiesterase
FNV65_RS11110	COG1309	transcriptional regulator
FNV65_RS11135	COG0640	Transcriptional regulator
FNV65_RS11140	COG1902	pentaerythritol trinitrate reductase activity
FNV65_RS11155	COG2197	response regulator
FNV65_RS11160	COG4585	Histidine kinase
FNV65_RS11165	COG3963	phosphatidate phosphatase activity
FNV65_RS11190	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FNV65_RS11190	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FNV65_RS11230	COG0714	Associated with various cellular activities
FNV65_RS11235	COG3552	Protein containing von Willebrand factor type A (VWA) domain
FNV65_RS11265	COG0596	Alpha beta hydrolase
FNV65_RS11270	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FNV65_RS11270	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FNV65_RS11275	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FNV65_RS11285	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FNV65_RS11300	COG2706	6-phosphogluconolactonase activity
FNV65_RS11305	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
FNV65_RS11340	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FNV65_RS11345	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FNV65_RS11350	COG2080	2 iron, 2 sulfur cluster binding
FNV65_RS11360	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FNV65_RS11375	COG2770	Histidine kinase
FNV65_RS11375	COG2208	phosphoserine phosphatase activity
FNV65_RS11395	COG0745	RESPONSE REGULATOR receiver
FNV65_RS11430	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS11490	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS11495	COG1733	regulation of RNA biosynthetic process
FNV65_RS11520	COG0667	Aldo Keto reductase
FNV65_RS11525	COG4221	oxidoreductase activity
FNV65_RS11545	COG0513	Belongs to the DEAD box helicase family
FNV65_RS11555	COG0432	Pfam Uncharacterised protein family UPF0047
FNV65_RS11560	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNV65_RS11565	COG1116	anion transmembrane transporter activity
FNV65_RS11575	COG2072	flavoprotein involved in K transport
FNV65_RS11585	COG1132	(ABC) transporter
FNV65_RS11595	COG1301	dicarboxylic acid transport
FNV65_RS11615	COG1132	(ABC) transporter
FNV65_RS11625	COG0254	rRNA binding
FNV65_RS11640	COG1946	Acyl-CoA thioesterase
FNV65_RS11650	COG2018	Roadblock/LC7 domain
FNV65_RS11715	COG3239	Fatty acid desaturase
FNV65_RS11720	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FNV65_RS11740	COG2115	Belongs to the xylose isomerase family
FNV65_RS11750	COG1940	carbohydrate kinase activity
FNV65_RS11750	COG1846	Transcriptional regulator
FNV65_RS11755	COG1113	amino acid transport
FNV65_RS11775	COG1012	belongs to the aldehyde dehydrogenase family
FNV65_RS11815	COG0515	serine threonine protein kinase
FNV65_RS11840	COG1960	acyl-CoA dehydrogenase activity
FNV65_RS11845	COG1960	acyl-CoA dehydrogenase activity
FNV65_RS11860	COG0492	ferredoxin-NADP+ reductase activity
FNV65_RS11865	COG1793	dna ligase
FNV65_RS11875	COG1012	belongs to the aldehyde dehydrogenase family
FNV65_RS11890	COG3424	synthase
FNV65_RS11895	COG2124	cytochrome p450
FNV65_RS11905	COG1960	acyl-CoA dehydrogenase activity
FNV65_RS11915	COG0242	peptide deformylase activity
FNV65_RS11925	COG3442	glutamine amidotransferase
FNV65_RS11930	COG0205	6-phosphofructokinase activity
FNV65_RS11945	COG2815	serine threonine protein kinase
FNV65_RS11945	COG0515	serine threonine protein kinase
FNV65_RS11950	COG3275	phosphorelay sensor kinase activity
FNV65_RS11955	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FNV65_RS11965	COG3279	Response regulator of the LytR AlgR family
FNV65_RS11975	COG1834	amidinotransferase
FNV65_RS11980	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FNV65_RS11990	COG1510	regulation of RNA biosynthetic process
FNV65_RS12025	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FNV65_RS12050	COG0829	nickel cation binding
FNV65_RS12055	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FNV65_RS12065	COG0804	urea catabolic process
FNV65_RS12070	COG0832	Belongs to the urease beta subunit family
FNV65_RS12075	COG0831	urea catabolic process
FNV65_RS12085	COG0740	serine-type endopeptidase activity
FNV65_RS12125	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FNV65_RS12130	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FNV65_RS12135	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FNV65_RS12145	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FNV65_RS12150	COG2226	methyltransferase
FNV65_RS12225	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FNV65_RS12235	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FNV65_RS12240	COG3663	DNA glycosylase
FNV65_RS12260	COG4585	Histidine kinase
FNV65_RS12265	COG2197	response regulator
FNV65_RS12270	COG1940	carbohydrate kinase activity
FNV65_RS12275	COG2188	Transcriptional regulator
FNV65_RS12280	COG1595	DNA-templated transcription, initiation
FNV65_RS12295	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FNV65_RS12310	COG0626	cystathionine gamma-synthase activity
FNV65_RS12330	COG0583	DNA-binding transcription factor activity
FNV65_RS12340	COG1522	sequence-specific DNA binding
FNV65_RS12345	COG0419	ATPase involved in DNA repair
FNV65_RS12350	COG0420	3'-5' exonuclease activity
FNV65_RS12355	COG1739	Uncharacterized protein family UPF0029
FNV65_RS12375	COG2197	response regulator
FNV65_RS12385	COG1960	acyl-CoA dehydrogenase activity
FNV65_RS12400	COG1832	CoA-binding protein
FNV65_RS12410	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FNV65_RS12415	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FNV65_RS12440	COG2326	polyphosphate kinase activity
FNV65_RS12470	COG0110	maltose O-acetyltransferase activity
FNV65_RS12490	COG1472	Belongs to the glycosyl hydrolase 3 family
FNV65_RS12505	COG1609	Transcriptional regulator
FNV65_RS12545	COG0076	glutamate decarboxylase activity
FNV65_RS12570	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FNV65_RS12585	COG0183	Belongs to the thiolase family
FNV65_RS12610	COG1968	undecaprenyl-diphosphatase activity
FNV65_RS12635	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS12655	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV65_RS12665	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FNV65_RS12675	COG2318	DinB family
FNV65_RS12690	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FNV65_RS12695	COG0747	negative chemotaxis
FNV65_RS12730	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FNV65_RS12740	COG1760	l-serine dehydratase
FNV65_RS12745	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FNV65_RS12750	COG0509	glycine decarboxylation via glycine cleavage system
FNV65_RS12790	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FNV65_RS12810	COG4175	Glycine betaine
FNV65_RS12810	COG0517	IMP dehydrogenase activity
FNV65_RS12815	COG1012	belongs to the aldehyde dehydrogenase family
FNV65_RS12835	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FNV65_RS12845	COG4638	Rieske (2fe-2S)
FNV65_RS12850	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FNV65_RS12860	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNV65_RS12900	COG0697	spore germination
FNV65_RS12975	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FNV65_RS12975	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FNV65_RS12985	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FNV65_RS13005	COG1716	ATPase activity
FNV65_RS13025	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FNV65_RS13060	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FNV65_RS13075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FNV65_RS13080	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FNV65_RS13090	COG2816	NAD+ diphosphatase activity
FNV65_RS13095	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
FNV65_RS13105	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FNV65_RS13110	COG3706	GGDEF domain
FNV65_RS13115	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FNV65_RS13120	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FNV65_RS13140	COG2018	Roadblock/LC7 domain
FNV65_RS13190	COG2814	Major facilitator Superfamily
FNV65_RS13195	COG4336	lyase activity
FNV65_RS13200	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FNV65_RS13205	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FNV65_RS13210	COG1984	allophanate hydrolase subunit 2
FNV65_RS13215	COG2755	lipolytic protein G-D-S-L family
FNV65_RS13220	COG0438	transferase activity, transferring glycosyl groups
FNV65_RS13225	COG0438	transferase activity, transferring glycosyl groups
FNV65_RS13250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FNV65_RS13265	COG2270	Major facilitator Superfamily
FNV65_RS13280	COG0463	Glycosyl transferase, family 2
FNV65_RS13315	COG1960	acyl-CoA dehydrogenase activity
FNV65_RS13325	COG1309	transcriptional regulator
FNV65_RS13370	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FNV65_RS13375	COG0140	phosphoribosyl-ATP diphosphatase activity
FNV65_RS13380	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FNV65_RS13385	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FNV65_RS13385	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FNV65_RS13390	COG3201	nicotinamide mononucleotide transporter
FNV65_RS13400	COG1940	carbohydrate kinase activity
FNV65_RS13400	COG1846	Transcriptional regulator
FNV65_RS13405	COG2223	nitrite transmembrane transporter activity
FNV65_RS13420	COG2233	PERMEase
FNV65_RS13445	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FNV65_RS13465	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FNV65_RS13470	COG3842	ATPase activity
FNV65_RS13480	COG1176	ABC-type spermidine putrescine transport system, permease component I
FNV65_RS13490	COG2188	Transcriptional regulator
FNV65_RS13500	COG0531	amino acid
FNV65_RS13520	COG2390	Transcriptional regulator
FNV65_RS13525	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FNV65_RS13535	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FNV65_RS13555	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FNV65_RS13570	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FNV65_RS13585	COG0194	GDP metabolic process
FNV65_RS13595	COG0284	orotidine-5'-phosphate decarboxylase activity
FNV65_RS13600	COG0167	dihydroorotate dehydrogenase activity
FNV65_RS13605	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FNV65_RS13610	COG0505	Belongs to the CarA family
FNV65_RS13620	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FNV65_RS13625	COG0540	Belongs to the ATCase OTCase family
FNV65_RS13630	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FNV65_RS13640	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FNV65_RS13645	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FNV65_RS13650	COG0006	proline dipeptidase activity
FNV65_RS13660	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FNV65_RS13665	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FNV65_RS13670	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FNV65_RS13675	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FNV65_RS13680	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FNV65_RS13690	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FNV65_RS13695	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FNV65_RS13715	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FNV65_RS13730	COG1131	(ABC) transporter
FNV65_RS13740	COG4585	Histidine kinase
FNV65_RS13745	COG2197	response regulator
FNV65_RS13750	COG0124	histidyl-tRNA synthetase
FNV65_RS13760	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FNV65_RS13765	COG1196	nuclear chromosome segregation
FNV65_RS13770	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FNV65_RS13780	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FNV65_RS13785	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FNV65_RS13790	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FNV65_RS13800	COG2255	four-way junction helicase activity
FNV65_RS13805	COG0632	four-way junction helicase activity
FNV65_RS13810	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FNV65_RS13815	COG0217	transcriptional regulatory protein
FNV65_RS13820	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
FNV65_RS13825	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
FNV65_RS13845	COG0438	transferase activity, transferring glycosyl groups
FNV65_RS13855	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FNV65_RS13875	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FNV65_RS13880	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FNV65_RS13895	COG2176	DNA-directed DNA polymerase activity
FNV65_RS13895	COG5002	protein histidine kinase activity
FNV65_RS13925	COG0395	ABC-type sugar transport system, permease component
FNV65_RS13930	COG1175	transmembrane transport
FNV65_RS13985	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FNV65_RS13985	COG0512	Glutamine amidotransferase of anthranilate synthase
FNV65_RS14045	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FNV65_RS14045	COG1648	precorrin-2 dehydrogenase activity
FNV65_RS14050	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FNV65_RS14065	COG1464	Belongs to the NlpA lipoprotein family
FNV65_RS14070	COG2011	ABC-type metal ion transport system permease component
FNV65_RS14075	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FNV65_RS14110	COG0318	PFAM AMP-dependent synthetase and ligase
FNV65_RS14110	COG0204	Acyl-transferase
FNV65_RS14115	COG0477	Major facilitator Superfamily
FNV65_RS14130	COG0165	Argininosuccinate lyase
FNV65_RS14135	COG0137	argininosuccinate synthase activity
FNV65_RS14155	COG2205	protein histidine kinase activity
FNV65_RS14160	COG0745	RESPONSE REGULATOR receiver
FNV65_RS14190	COG1438	arginine binding
FNV65_RS14195	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FNV65_RS14200	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FNV65_RS14205	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FNV65_RS14210	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FNV65_RS14230	COG0789	Transcriptional regulator
FNV65_RS14265	COG0697	spore germination
FNV65_RS14275	COG1649	PFAM Uncharacterised BCR, COG1649
FNV65_RS14305	COG0072	phenylalanine-tRNA ligase activity
FNV65_RS14305	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FNV65_RS14310	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FNV65_RS14315	COG5002	protein histidine kinase activity
FNV65_RS14320	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FNV65_RS14325	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FNV65_RS14330	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FNV65_RS14335	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FNV65_RS14390	COG1012	belongs to the aldehyde dehydrogenase family
FNV65_RS14395	COG0174	glutamine synthetase
FNV65_RS14405	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FNV65_RS14445	COG4176	ABC-type proline glycine betaine transport system permease component
FNV65_RS14450	COG0517	IMP dehydrogenase activity
FNV65_RS14450	COG4175	Glycine betaine
FNV65_RS14455	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FNV65_RS14485	COG0564	pseudouridine synthase activity
FNV65_RS14515	COG1309	transcriptional regulator
FNV65_RS14555	COG0805	protein transport
FNV65_RS14560	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FNV65_RS14590	COG0545	Peptidyl-prolyl cis-trans isomerase
FNV65_RS14595	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
FNV65_RS14605	COG1609	Transcriptional regulator
FNV65_RS14610	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
FNV65_RS14615	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
FNV65_RS14630	COG4122	O-methyltransferase activity
FNV65_RS14635	COG1222	aaa ATPase
FNV65_RS14660	COG0517	IMP dehydrogenase activity
FNV65_RS14660	COG1994	Peptidase M50
FNV65_RS14670	COG2197	response regulator
FNV65_RS14680	COG4166	transmembrane transport
FNV65_RS14690	COG1410	methionine synthase
FNV65_RS14690	COG0646	methionine synthase
FNV65_RS14695	COG1414	Transcriptional regulator
FNV65_RS14700	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FNV65_RS14705	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FNV65_RS14710	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FNV65_RS14715	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
FNV65_RS14725	COG1129	ABC transporter
FNV65_RS14735	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
FNV65_RS14740	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
FNV65_RS14745	COG0235	Class ii aldolase
FNV65_RS14750	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FNV65_RS14750	COG0235	Class ii aldolase
FNV65_RS14755	COG2186	Transcriptional regulator
FNV65_RS14780	COG0215	cysteine-tRNA ligase activity
FNV65_RS14800	COG0598	Magnesium transport protein CorA
FNV65_RS14810	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV65_RS14815	COG0667	Aldo Keto reductase
FNV65_RS14845	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FNV65_RS14860	COG0308	aminopeptidase N
FNV65_RS14865	COG3012	SEC-C Motif Domain Protein
FNV65_RS14870	COG2186	Transcriptional regulator
FNV65_RS14875	COG3265	gluconokinase activity
FNV65_RS14885	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS14890	COG1063	alcohol dehydrogenase
FNV65_RS14915	COG3573	Dehydrogenase
FNV65_RS14925	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FNV65_RS14930	COG2149	membrane
FNV65_RS14960	COG0318	PFAM AMP-dependent synthetase and ligase
FNV65_RS14970	COG3876	Protein conserved in bacteria
FNV65_RS14990	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FNV65_RS14990	COG0072	phenylalanine-tRNA ligase activity
FNV65_RS14995	COG0789	Transcriptional regulator
FNV65_RS15015	COG1960	acyl-CoA dehydrogenase activity
FNV65_RS15025	COG0640	Transcriptional regulator
FNV65_RS15030	COG0697	spore germination
FNV65_RS15055	COG2851	Citrate transporter
FNV65_RS15060	COG0243	molybdopterin cofactor binding
FNV65_RS15065	COG1309	transcriptional regulator
FNV65_RS15075	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FNV65_RS15080	COG2188	Transcriptional regulator
FNV65_RS15115	COG1595	DNA-templated transcription, initiation
FNV65_RS15135	COG2815	serine threonine protein kinase
FNV65_RS15135	COG0515	serine threonine protein kinase
FNV65_RS15140	COG2755	lipolytic protein G-D-S-L family
FNV65_RS15160	COG0726	polysaccharide deacetylase
FNV65_RS15160	COG1649	PFAM Uncharacterised BCR, COG1649
FNV65_RS15185	COG1725	Transcriptional regulator
FNV65_RS15225	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FNV65_RS15225	COG0662	Cupin 2, conserved barrel domain protein
FNV65_RS15230	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FNV65_RS15235	COG0587	DNA-directed DNA polymerase activity
FNV65_RS15245	COG0330	HflC and HflK could
FNV65_RS15260	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV65_RS15265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV65_RS15270	COG1126	abc transporter atp-binding protein
FNV65_RS15280	COG0765	amino acid transport
FNV65_RS15285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNV65_RS15295	COG1799	cell septum assembly
FNV65_RS15300	COG1960	acyl-CoA dehydrogenase activity
FNV65_RS15305	COG0477	Major facilitator Superfamily
FNV65_RS15315	COG0671	phosphoesterase, PA-phosphatase related
FNV65_RS15325	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FNV65_RS15355	COG1129	ABC transporter
FNV65_RS15385	COG1160	GTP binding
FNV65_RS15395	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FNV65_RS15435	COG3541	Predicted nucleotidyltransferase
FNV65_RS15450	COG1187	pseudouridine synthase activity
FNV65_RS15455	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FNV65_RS15460	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FNV65_RS15475	COG0686	Belongs to the AlaDH PNT family
FNV65_RS15485	COG0494	nUDIX hydrolase
FNV65_RS15490	COG0504	CTP synthase activity
FNV65_RS15495	COG3387	PFAM Glycoside hydrolase 15-related
FNV65_RS15520	COG0497	DNA recombination
FNV65_RS15525	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FNV65_RS15545	COG1120	ATPase activity
FNV65_RS15550	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FNV65_RS15555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FNV65_RS15560	COG0647	UMP catabolic process
FNV65_RS15600	COG2094	Belongs to the DNA glycosylase MPG family
FNV65_RS15610	COG1881	PFAM PEBP family protein
FNV65_RS15630	COG1119	ATPase activity
FNV65_RS15655	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS15660	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FNV65_RS15670	COG0842	Transport permease protein
FNV65_RS15670	COG1131	(ABC) transporter
FNV65_RS15670	COG1716	ATPase activity
FNV65_RS15680	COG3830	Belongs to the UPF0237 family
FNV65_RS15680	COG0560	Phosphoserine phosphatase
FNV65_RS15685	COG0588	phosphoglycerate mutase activity
FNV65_RS15700	COG2186	Transcriptional regulator
FNV65_RS15710	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FNV65_RS15715	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS15730	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FNV65_RS15750	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FNV65_RS15755	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FNV65_RS15775	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNV65_RS15825	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FNV65_RS15840	COG3387	PFAM Glycoside hydrolase 15-related
FNV65_RS15890	COG0488	(ABC) transporter
FNV65_RS15920	COG0235	Class ii aldolase
FNV65_RS15940	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FNV65_RS15945	COG1492	cobalamin metabolic process
FNV65_RS15960	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
FNV65_RS15965	COG1797	cobyrinic acid a,c-diamide synthase activity
FNV65_RS16030	COG0765	amino acid transport
FNV65_RS16035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNV65_RS16040	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FNV65_RS16045	COG0456	acetyltransferase
FNV65_RS16050	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FNV65_RS16055	COG1917	Cupin 2, conserved barrel domain protein
FNV65_RS16060	COG5285	phytanoyl-CoA dioxygenase
FNV65_RS16065	COG3844	kynureninase activity
FNV65_RS16090	COG1414	Transcriptional regulator
FNV65_RS16100	COG0768	penicillin binding
FNV65_RS16105	COG2252	PERMEase
FNV65_RS16110	COG1595	DNA-templated transcription, initiation
FNV65_RS16125	COG4733	cellulase activity
FNV65_RS16165	COG4677	pectinesterase activity
FNV65_RS16170	COG3866	Pectate lyase
FNV65_RS16175	COG2755	lipolytic protein G-D-S-L family
FNV65_RS16180	COG1653	transport
FNV65_RS16200	COG0395	ABC-type sugar transport system, permease component
FNV65_RS16215	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FNV65_RS16220	COG1802	Transcriptional regulator
FNV65_RS16245	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FNV65_RS16250	COG1349	DNA-binding transcription factor activity
FNV65_RS16265	COG0395	ABC-type sugar transport system, permease component
FNV65_RS16270	COG1063	alcohol dehydrogenase
FNV65_RS16280	COG1309	transcriptional regulator
FNV65_RS16295	COG1802	Transcriptional regulator
FNV65_RS16335	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FNV65_RS16350	COG3973	AAA domain
FNV65_RS16365	COG2171	N-acyltransferase activity
FNV65_RS16370	COG3226	Transcriptional regulator
FNV65_RS16375	COG2076	Multidrug Resistance protein
FNV65_RS16390	COG2151	metal-sulfur cluster biosynthetic enzyme
FNV65_RS16395	COG0822	iron-sulfur transferase activity
FNV65_RS16400	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FNV65_RS16405	COG0396	ATPase activity
FNV65_RS16415	COG0719	Fe-S assembly protein
FNV65_RS16430	COG2746	aminoglycoside 3-N-acetyltransferase activity
FNV65_RS16435	COG1131	(ABC) transporter
FNV65_RS16460	COG0109	protoheme IX farnesyltransferase activity
FNV65_RS16475	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FNV65_RS16490	COG0363	glucosamine-6-phosphate deaminase activity
FNV65_RS16495	COG0395	ABC-type sugar transport system, permease component
FNV65_RS16500	COG1175	transmembrane transport
FNV65_RS16510	COG0366	Alpha amylase catalytic
FNV65_RS16515	COG1653	transport
FNV65_RS16520	COG1695	Transcriptional regulator
FNV65_RS16525	COG1136	(ABC) transporter
FNV65_RS16540	COG0166	Belongs to the GPI family
FNV65_RS16555	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FNV65_RS16560	COG0149	triose-phosphate isomerase activity
FNV65_RS16565	COG0126	phosphoglycerate kinase activity
FNV65_RS16570	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FNV65_RS16580	COG1481	regulation of sporulation
FNV65_RS16585	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FNV65_RS16590	COG1660	Displays ATPase and GTPase activities
FNV65_RS16595	COG0322	excinuclease ABC activity
FNV65_RS16610	COG1609	Transcriptional regulator
FNV65_RS16620	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FNV65_RS16635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNV65_RS16640	COG0765	amino acid transport
FNV65_RS16650	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FNV65_RS16655	COG0477	Major facilitator Superfamily
FNV65_RS16660	COG0387	Pfam Sodium calcium exchanger
FNV65_RS16680	COG0556	nucleotide-excision repair
FNV65_RS16690	COG0584	glycerophosphoryl diester phosphodiesterase
FNV65_RS16695	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FNV65_RS16715	COG2313	pseudouridylate synthase activity
FNV65_RS16725	COG2226	methyltransferase
FNV65_RS16730	COG0598	Magnesium transport protein CorA
FNV65_RS16760	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FNV65_RS16765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FNV65_RS16805	COG0402	S-adenosylhomocysteine deaminase activity
FNV65_RS16830	COG1201	RNA secondary structure unwinding
FNV65_RS16880	COG2856	Zn peptidase
FNV65_RS16935	COG1953	Uracil, thiamine, allantoin
FNV65_RS16940	COG1802	Transcriptional regulator
FNV65_RS16945	COG2267	carboxylic ester hydrolase activity
FNV65_RS16955	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
FNV65_RS16985	COG0237	dephospho-CoA kinase activity
FNV65_RS17005	COG2226	methyltransferase
FNV65_RS17010	COG1643	Atp-dependent helicase
FNV65_RS17050	COG2050	protein possibly involved in aromatic compounds catabolism
FNV65_RS17110	COG0737	Belongs to the 5'-nucleotidase family
FNV65_RS17130	COG4566	intracellular signal transduction
FNV65_RS17135	COG1605	Chorismate mutase
FNV65_RS17135	COG0287	Prephenate dehydrogenase
FNV65_RS17175	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS17180	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS17185	COG1024	Enoyl-CoA hydratase
FNV65_RS17210	COG0183	Belongs to the thiolase family
FNV65_RS17215	COG1309	transcriptional regulator
FNV65_RS17225	COG1960	acyl-CoA dehydrogenase activity
FNV65_RS17230	COG1960	acyl-CoA dehydrogenase activity
FNV65_RS17235	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FNV65_RS17245	COG2304	oxidoreductase activity
FNV65_RS17260	COG4591	ABC-type transport system involved in lipoprotein release permease component
FNV65_RS17260	COG1136	(ABC) transporter
FNV65_RS17275	COG0577	efflux transmembrane transporter activity
FNV65_RS17275	COG1136	(ABC) transporter
FNV65_RS17285	COG0070	glutamate synthase
FNV65_RS17285	COG0067	glutamate synthase
FNV65_RS17285	COG0069	glutamate synthase activity
FNV65_RS17315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNV65_RS17320	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNV65_RS17325	COG2301	Belongs to the HpcH HpaI aldolase family
FNV65_RS17330	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FNV65_RS17340	COG0159	tryptophan synthase activity
FNV65_RS17345	COG0133	tryptophan synthase activity
FNV65_RS17355	COG0134	indole-3-glycerol-phosphate synthase activity
FNV65_RS17380	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FNV65_RS17400	COG0107	imidazoleglycerol-phosphate synthase activity
FNV65_RS17405	COG0251	oxidation-reduction process
FNV65_RS17410	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FNV65_RS17415	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FNV65_RS17420	COG0131	Imidazoleglycerol-phosphate dehydratase
FNV65_RS17425	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FNV65_RS17430	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FNV65_RS17450	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FNV65_RS17470	COG1432	Conserved Protein
FNV65_RS17475	COG0587	DNA-directed DNA polymerase activity
FNV65_RS17535	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FNV65_RS17550	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FNV65_RS17555	COG3599	regulation of cell shape
FNV65_RS17565	COG1799	cell septum assembly
FNV65_RS17575	COG1496	oxidoreductase activity
FNV65_RS17580	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FNV65_RS17595	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FNV65_RS17605	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FNV65_RS17610	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FNV65_RS17620	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FNV65_RS17625	COG0768	penicillin binding
FNV65_RS17635	COG0275	rRNA processing
FNV65_RS17645	COG0714	Associated with various cellular activities
FNV65_RS17665	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FNV65_RS17675	COG1126	abc transporter atp-binding protein
FNV65_RS17685	COG1309	transcriptional regulator
FNV65_RS17710	COG0352	thiamine-phosphate diphosphorylase activity
FNV65_RS17730	COG2022	thiamine diphosphate biosynthetic process
FNV65_RS17730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNV65_RS17740	COG2022	thiamine diphosphate biosynthetic process
FNV65_RS17745	COG0515	serine threonine protein kinase
FNV65_RS17745	COG2815	serine threonine protein kinase
FNV65_RS17750	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FNV65_RS17755	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FNV65_RS17760	COG2193	ferroxidase activity
FNV65_RS17765	COG0243	molybdopterin cofactor binding
FNV65_RS17770	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FNV65_RS17790	COG0205	6-phosphofructokinase activity
FNV65_RS17800	COG4585	Histidine kinase
FNV65_RS17825	COG1940	carbohydrate kinase activity
FNV65_RS17835	COG0003	Pfam Anion-transporting ATPase
FNV65_RS17875	COG0534	Mate efflux family protein
FNV65_RS17895	COG3103	Sh3 type 3 domain protein
FNV65_RS17895	COG0791	NLP P60 protein
FNV65_RS17895	COG1388	LysM domain
FNV65_RS17920	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FNV65_RS17925	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FNV65_RS17930	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FNV65_RS17935	COG0723	plastoquinol--plastocyanin reductase activity
FNV65_RS17940	COG2010	Cytochrome c
FNV65_RS17945	COG1845	cytochrome c oxidase, subunit III
FNV65_RS17955	COG1376	ErfK ybiS ycfS ynhG family protein
FNV65_RS17965	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FNV65_RS17970	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FNV65_RS17980	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNV65_RS18005	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FNV65_RS18010	COG2197	response regulator
FNV65_RS18035	COG2226	methyltransferase
FNV65_RS18040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FNV65_RS18060	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FNV65_RS18065	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FNV65_RS18065	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FNV65_RS18080	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FNV65_RS18085	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FNV65_RS18090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FNV65_RS18095	COG0508	dehydrogenase complex catalyzes the overall conversion of
FNV65_RS18110	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FNV65_RS18140	COG0454	-acetyltransferase
FNV65_RS18160	COG0321	lipoyl(octanoyl) transferase activity
FNV65_RS18165	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FNV65_RS18185	COG0174	glutamine synthetase
FNV65_RS18195	COG0501	Belongs to the peptidase M48B family
FNV65_RS18245	COG0745	RESPONSE REGULATOR receiver
FNV65_RS18260	COG2197	response regulator
FNV65_RS18290	COG1309	transcriptional regulator
FNV65_RS18325	COG1175	transmembrane transport
FNV65_RS18330	COG3833	ABC-type maltose transport systems, permease component
FNV65_RS18335	COG0366	Alpha amylase catalytic
FNV65_RS18340	COG1609	Transcriptional regulator
FNV65_RS18350	COG0583	DNA-binding transcription factor activity
FNV65_RS18355	COG0697	spore germination
FNV65_RS18360	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FNV65_RS18365	COG3511	phospholipase C
FNV65_RS18405	COG0174	glutamine synthetase
FNV65_RS18410	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FNV65_RS18410	COG1017	nitric oxide dioxygenase activity
FNV65_RS18415	COG1959	2 iron, 2 sulfur cluster binding
FNV65_RS18435	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FNV65_RS18435	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FNV65_RS18440	COG2814	Major facilitator Superfamily
FNV65_RS18455	COG0477	Major facilitator Superfamily
FNV65_RS18460	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FNV65_RS18480	COG1994	Peptidase M50
FNV65_RS18540	COG2822	iron ion transport
FNV65_RS18545	COG2837	iron assimilation
FNV65_RS18550	COG0672	)-iron permease
FNV65_RS18560	COG0495	leucyl-tRNA aminoacylation
FNV65_RS18570	COG1834	amidinotransferase
FNV65_RS18580	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FNV65_RS18585	COG2814	Major facilitator Superfamily
FNV65_RS18600	COG1686	Belongs to the peptidase S11 family
FNV65_RS18610	COG1136	(ABC) transporter
FNV65_RS18615	COG0667	Aldo Keto reductase
FNV65_RS18625	COG2259	Doxx family
FNV65_RS18640	COG0406	alpha-ribazole phosphatase activity
FNV65_RS18650	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS18655	COG0673	inositol 2-dehydrogenase activity
FNV65_RS18665	COG0583	DNA-binding transcription factor activity
FNV65_RS18690	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FNV65_RS18720	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FNV65_RS18795	COG3022	response to hydroperoxide
FNV65_RS18800	COG0800	Aldolase
FNV65_RS18825	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FNV65_RS18840	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS18850	COG2030	dehydratase
FNV65_RS18855	COG1131	(ABC) transporter
FNV65_RS18865	COG4585	Histidine kinase
FNV65_RS18875	COG2197	response regulator
FNV65_RS18895	COG0183	Belongs to the thiolase family
FNV65_RS18900	COG0477	Major facilitator Superfamily
FNV65_RS18920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV65_RS18955	COG1309	transcriptional regulator
FNV65_RS19015	COG3845	ABC transporter
FNV65_RS19035	COG3619	membrane
FNV65_RS19060	COG0183	Belongs to the thiolase family
FNV65_RS19065	COG2124	cytochrome p450
FNV65_RS19085	COG4122	O-methyltransferase activity
FNV65_RS19165	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FNV65_RS19170	COG1335	isochorismatase
FNV65_RS19175	COG0477	Major facilitator Superfamily
FNV65_RS19195	COG1733	regulation of RNA biosynthetic process
FNV65_RS19300	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FNV65_RS19315	COG1358	cellular component organization or biogenesis
FNV65_RS19365	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FNV65_RS19370	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FNV65_RS19375	COG0477	Major facilitator Superfamily
FNV65_RS19380	COG1309	transcriptional regulator
FNV65_RS19395	COG0667	Aldo Keto reductase
FNV65_RS19400	COG0789	Transcriptional regulator
FNV65_RS19415	COG1741	Belongs to the pirin family
FNV65_RS19430	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FNV65_RS19435	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FNV65_RS19440	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FNV65_RS19470	COG1309	transcriptional regulator
FNV65_RS19485	COG2084	Dehydrogenase
FNV65_RS19520	COG1764	response to oxidative stress
FNV65_RS19525	COG2130	NADP-dependent
FNV65_RS19540	COG4948	Mandelate Racemase Muconate Lactonizing
FNV65_RS19555	COG4213	ABC transporter substrate-binding protein
FNV65_RS19565	COG4214	carbohydrate transport
FNV65_RS19575	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FNV65_RS19610	COG1764	response to oxidative stress
FNV65_RS19640	COG0596	Alpha beta hydrolase
FNV65_RS19660	COG2318	DinB family
FNV65_RS19685	COG3507	Belongs to the glycosyl hydrolase 43 family
FNV65_RS19690	COG0395	ABC-type sugar transport system, permease component
FNV65_RS19695	COG1175	transmembrane transport
FNV65_RS19705	COG3386	PFAM SMP-30 Gluconolaconase
FNV65_RS19710	COG1414	Transcriptional regulator
FNV65_RS19735	COG4981	capsule polysaccharide biosynthetic process
FNV65_RS19810	COG0318	PFAM AMP-dependent synthetase and ligase
FNV65_RS19815	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FNV65_RS19815	COG0825	malonyl-CoA metabolic process
FNV65_RS19820	COG1404	Belongs to the peptidase S8 family
FNV65_RS19825	COG1077	Cell shape determining protein MreB Mrl
FNV65_RS19870	COG0559	Belongs to the binding-protein-dependent transport system permease family
FNV65_RS19890	COG0318	PFAM AMP-dependent synthetase and ligase
FNV65_RS19925	COG1070	Carbohydrate kinase
FNV65_RS19940	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FNV65_RS19945	COG0358	DNA primase activity
FNV65_RS19955	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FNV65_RS19965	COG2949	membrane
FNV65_RS20030	COG2146	nitrite reductase [NAD(P)H] activity
FNV65_RS20030	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FNV65_RS20040	COG1309	transcriptional regulator
FNV65_RS20045	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS20060	COG1136	(ABC) transporter
FNV65_RS20080	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FNV65_RS20080	COG0574	Belongs to the PEP-utilizing enzyme family
FNV65_RS20085	COG1940	carbohydrate kinase activity
FNV65_RS20085	COG1846	Transcriptional regulator
FNV65_RS20120	COG0477	Major facilitator Superfamily
FNV65_RS20150	COG0667	Aldo Keto reductase
FNV65_RS20160	COG1309	transcriptional regulator
FNV65_RS20165	COG0300	oxidoreductase activity
FNV65_RS20170	COG0423	glycine-tRNA ligase activity
FNV65_RS20175	COG0803	Belongs to the bacterial solute-binding protein 9 family
FNV65_RS20180	COG1121	(ABC) transporter
FNV65_RS20185	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FNV65_RS20195	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FNV65_RS20200	COG1381	Involved in DNA repair and RecF pathway recombination
FNV65_RS20210	COG0515	serine threonine protein kinase
FNV65_RS20210	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FNV65_RS20250	COG0456	acetyltransferase
FNV65_RS20255	COG2197	response regulator
FNV65_RS20260	COG4585	Histidine kinase
FNV65_RS20265	COG1131	(ABC) transporter
FNV65_RS20280	COG2186	Transcriptional regulator
FNV65_RS20285	COG0747	negative chemotaxis
FNV65_RS20295	COG0444	Belongs to the ABC transporter superfamily
FNV65_RS20300	COG4608	Belongs to the ABC transporter superfamily
FNV65_RS20305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FNV65_RS20320	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FNV65_RS20340	COG2723	6-phospho-beta-galactosidase activity
FNV65_RS20385	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FNV65_RS20405	COG2315	Protein conserved in bacteria
FNV65_RS20415	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FNV65_RS20435	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FNV65_RS20440	COG1234	tRNA 3'-trailer cleavage
FNV65_RS20445	COG0537	adenosine 5'-monophosphoramidase activity
FNV65_RS20450	COG4946	Tricorn protease homolog
FNV65_RS20450	COG0793	Belongs to the peptidase S41A family
FNV65_RS20475	COG0484	heat shock protein binding
FNV65_RS20480	COG1420	regulation of RNA biosynthetic process
FNV65_RS20520	COG0481	GTPase activity
FNV65_RS20525	COG0268	Binds directly to 16S ribosomal RNA
FNV65_RS20630	COG1555	photosystem II stabilization
FNV65_RS20630	COG1596	polysaccharide export
FNV65_RS20635	COG1307	EDD domain protein, DegV family
FNV65_RS20645	COG0495	leucyl-tRNA aminoacylation
FNV65_RS20685	COG0477	Major facilitator Superfamily
FNV65_RS20700	COG0588	phosphoglycerate mutase activity
FNV65_RS20705	COG0799	negative regulation of ribosome biogenesis
FNV65_RS20715	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FNV65_RS20720	COG0501	Belongs to the peptidase M48B family
FNV65_RS20735	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FNV65_RS20745	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FNV65_RS20755	COG0438	transferase activity, transferring glycosyl groups
FNV65_RS20760	COG0463	Glycosyl transferase, family 2
FNV65_RS20760	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FNV65_RS20765	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FNV65_RS20765	COG0463	Glycosyl transferase, family 2
FNV65_RS20780	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FNV65_RS20785	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FNV65_RS20790	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FNV65_RS20795	COG1530	ribonuclease E activity
FNV65_RS20825	COG1309	transcriptional regulator
FNV65_RS20830	COG0300	oxidoreductase activity
FNV65_RS20845	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FNV65_RS20855	COG0640	Transcriptional regulator
FNV65_RS20860	COG2226	methyltransferase
FNV65_RS20870	COG0477	Major facilitator Superfamily
FNV65_RS20905	COG0772	Belongs to the SEDS family
FNV65_RS20910	COG0768	penicillin binding
FNV65_RS20925	COG1077	Cell shape determining protein MreB Mrl
FNV65_RS20930	COG0105	UTP biosynthetic process
FNV65_RS20940	COG0285	dihydrofolate synthase activity
FNV65_RS20945	COG0525	valine-tRNA ligase activity
FNV65_RS20955	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FNV65_RS20960	COG0740	serine-type endopeptidase activity
FNV65_RS20965	COG0740	serine-type endopeptidase activity
FNV65_RS20970	COG0544	peptidyl-prolyl cis-trans isomerase activity
FNV65_RS20995	COG3594	Acyltransferase
FNV65_RS21010	COG4552	Acetyltransferase involved in intracellular survival and related
FNV65_RS21025	COG1113	amino acid transport
FNV65_RS21030	COG0515	serine threonine protein kinase
FNV65_RS21040	COG1268	BioY protein
FNV65_RS21045	COG1940	carbohydrate kinase activity
FNV65_RS21055	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNV65_RS21060	COG1116	anion transmembrane transporter activity
FNV65_RS21065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV65_RS21075	COG1113	amino acid transport
FNV65_RS21080	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FNV65_RS21085	COG0588	phosphoglycerate mutase activity
FNV65_RS21095	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FNV65_RS21175	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FNV65_RS21210	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FNV65_RS21235	COG2826	transposase and inactivated derivatives, IS30 family
FNV65_RS21240	COG1122	ATPase activity
FNV65_RS21265	COG0668	transmembrane transport
FNV65_RS21300	COG1175	transmembrane transport
FNV65_RS21305	COG0395	ABC-type sugar transport system, permease component
FNV65_RS21310	COG1486	melibiose metabolic process
FNV65_RS21325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNV65_RS21355	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FNV65_RS21360	COG2346	COG2346, Truncated hemoglobins
FNV65_RS21405	COG0489	protein tyrosine kinase activity
FNV65_RS21425	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FNV65_RS21450	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FNV65_RS21480	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FNV65_RS21490	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
FNV65_RS21540	COG0629	single-stranded DNA binding
FNV65_RS21645	COG3962	Belongs to the TPP enzyme family
FNV65_RS21650	COG3718	enzyme involved in inositol metabolism
FNV65_RS21660	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNV65_RS21685	COG2409	Drug exporters of the RND superfamily
FNV65_RS21715	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FNV65_RS21735	COG1129	ABC transporter
FNV65_RS21745	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNV65_RS21750	COG1869	D-ribose catabolic process
FNV65_RS21770	COG0673	inositol 2-dehydrogenase activity
FNV65_RS21775	COG1609	Transcriptional regulator
FNV65_RS21780	COG0456	acetyltransferase
FNV65_RS21780	COG1846	Transcriptional regulator
FNV65_RS21790	COG0181	hydroxymethylbilane synthase activity
FNV65_RS21795	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FNV65_RS21800	COG1472	Belongs to the glycosyl hydrolase 3 family
FNV65_RS21840	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FNV65_RS21845	COG2356	endonuclease I
FNV65_RS21850	COG0028	Belongs to the TPP enzyme family
FNV65_RS21860	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FNV65_RS21880	COG1946	Acyl-CoA thioesterase
FNV65_RS21890	COG1309	transcriptional regulator
FNV65_RS21895	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FNV65_RS21910	COG1960	acyl-CoA dehydrogenase activity
FNV65_RS21945	COG0076	glutamate decarboxylase activity
FNV65_RS21950	COG3486	L-lysine 6-monooxygenase (NADPH) activity
FNV65_RS21985	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FNV65_RS21995	COG0589	response to stress
FNV65_RS22010	COG4977	sequence-specific DNA binding
FNV65_RS22015	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FNV65_RS22050	COG0395	ABC-type sugar transport system, permease component
FNV65_RS22075	COG0745	RESPONSE REGULATOR receiver
FNV65_RS22100	COG0406	alpha-ribazole phosphatase activity
FNV65_RS22150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV65_RS22185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNV65_RS22190	COG0765	amino acid transport
FNV65_RS22195	COG0765	amino acid transport
FNV65_RS22200	COG1126	abc transporter atp-binding protein
FNV65_RS22215	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FNV65_RS22230	COG1362	aminopeptidase activity
FNV65_RS22250	COG0318	PFAM AMP-dependent synthetase and ligase
FNV65_RS22260	COG3397	chitin binding
FNV65_RS22335	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNV65_RS22340	COG2188	Transcriptional regulator
FNV65_RS22355	COG0673	inositol 2-dehydrogenase activity
FNV65_RS22360	COG4702	Belongs to the UPF0303 family
FNV65_RS22370	COG0706	membrane insertase activity
FNV65_RS22370	COG4455	Protein of avirulence locus involved in temperature-dependent protein secretion
FNV65_RS22390	COG3764	Sortase (surface protein transpeptidase)
FNV65_RS22400	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FNV65_RS22460	COG3250	beta-galactosidase activity
FNV65_RS22475	COG1846	Transcriptional regulator
FNV65_RS22505	COG2733	membrane
FNV65_RS22520	COG1131	(ABC) transporter
FNV65_RS22535	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FNV65_RS22570	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FNV65_RS22580	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FNV65_RS22585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FNV65_RS22590	COG1263	PTS System
FNV65_RS22595	COG1263	PTS System
FNV65_RS22610	COG3631	Ketosteroid isomerase-related protein
FNV65_RS22655	COG1113	amino acid transport
FNV65_RS22670	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FNV65_RS22680	COG1335	isochorismatase
FNV65_RS22715	COG0277	FAD linked oxidase domain protein
FNV65_RS22725	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FNV65_RS22735	COG1174	glycine betaine transport
FNV65_RS22755	COG3480	Lon protease (S16) C-terminal proteolytic domain
FNV65_RS22760	COG4948	Mandelate Racemase Muconate Lactonizing
FNV65_RS22770	COG0049	tRNA binding
FNV65_RS22780	COG0596	Alpha beta hydrolase
FNV65_RS22780	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FNV65_RS22790	COG0531	amino acid
FNV65_RS22840	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FNV65_RS22845	COG0395	ABC-type sugar transport system, permease component
FNV65_RS22850	COG1175	transmembrane transport
FNV65_RS22855	COG1653	transport
FNV65_RS22865	COG1678	Uncharacterized ACR, COG1678
FNV65_RS22870	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FNV65_RS22875	COG0776	regulation of translation
FNV65_RS22885	COG3973	AAA domain
FNV65_RS22915	COG2223	nitrite transmembrane transporter activity
FNV65_RS22935	COG0583	DNA-binding transcription factor activity
FNV65_RS22950	COG1175	transmembrane transport
FNV65_RS22955	COG0395	ABC-type sugar transport system, permease component
FNV65_RS22960	COG1501	Belongs to the glycosyl hydrolase 31 family
FNV65_RS22965	COG1609	Transcriptional regulator
FNV65_RS22990	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FNV65_RS22995	COG0793	Belongs to the peptidase S41A family
FNV65_RS23005	COG2884	Cell division ATP-binding protein ftsE
FNV65_RS23020	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FNV65_RS23025	COG0515	serine threonine protein kinase
FNV65_RS23030	COG0515	serine threonine protein kinase
FNV65_RS23050	COG1175	transmembrane transport
FNV65_RS23055	COG0395	ABC-type sugar transport system, permease component
FNV65_RS23060	COG0463	Glycosyl transferase, family 2
FNV65_RS23060	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FNV65_RS23065	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FNV65_RS23085	COG1764	response to oxidative stress
FNV65_RS23090	COG1846	Transcriptional regulator
FNV65_RS23105	COG1216	Glycosyl transferase, family 2
FNV65_RS23130	COG2197	response regulator
FNV65_RS23155	COG1134	teichoic acid transport
FNV65_RS23160	COG0438	transferase activity, transferring glycosyl groups
FNV65_RS23165	COG0463	Glycosyl transferase, family 2
FNV65_RS23165	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FNV65_RS23175	COG2902	Dehydrogenase
FNV65_RS23200	COG0653	protein targeting
FNV65_RS23210	COG3214	Protein conserved in bacteria
FNV65_RS23215	COG2197	response regulator
FNV65_RS23220	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FNV65_RS23230	COG0823	Involved in the tonB-independent uptake of proteins
FNV65_RS23235	COG5000	phosphorelay sensor kinase activity
FNV65_RS23235	COG5002	protein histidine kinase activity
FNV65_RS23240	COG0745	RESPONSE REGULATOR receiver
FNV65_RS23245	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FNV65_RS23265	COG0714	Associated with various cellular activities
FNV65_RS23310	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FNV65_RS23320	COG1482	cell wall glycoprotein biosynthetic process
FNV65_RS23330	COG2835	tetraacyldisaccharide 4'-kinase activity
FNV65_RS23335	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FNV65_RS23380	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FNV65_RS23385	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
FNV65_RS23385	COG0778	Nitroreductase
FNV65_RS23400	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FNV65_RS23420	COG1316	TRANSCRIPTIONal
FNV65_RS23440	COG1316	TRANSCRIPTIONal
FNV65_RS23450	COG1011	Hydrolase
FNV65_RS23465	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FNV65_RS23510	COG2205	protein histidine kinase activity
FNV65_RS23515	COG0745	RESPONSE REGULATOR receiver
FNV65_RS23520	COG3104	oligopeptide transport
FNV65_RS23575	COG1366	Belongs to the anti-sigma-factor antagonist family
FNV65_RS23580	COG1191	sigma factor activity
FNV65_RS23590	COG1228	amidohydrolase
FNV65_RS23600	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FNV65_RS23605	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FNV65_RS23650	COG2986	histidine ammonia-lyase
FNV65_RS23660	COG1174	glycine betaine transport
FNV65_RS23665	COG1174	glycine betaine transport
FNV65_RS23675	COG1609	Transcriptional regulator
FNV65_RS23690	COG0288	reversible hydration of carbon dioxide
FNV65_RS23705	COG2755	lipolytic protein G-D-S-L family
FNV65_RS23710	COG0183	Belongs to the thiolase family
FNV65_RS23755	COG0577	efflux transmembrane transporter activity
FNV65_RS23755	COG1136	(ABC) transporter
FNV65_RS23760	COG0577	efflux transmembrane transporter activity
FNV65_RS23765	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FNV65_RS23770	COG1252	NADH dehydrogenase
FNV65_RS23790	COG0148	phosphopyruvate hydratase activity
FNV65_RS23800	COG1652	LysM domain
FNV65_RS23805	COG2124	cytochrome p450
FNV65_RS23925	COG1309	transcriptional regulator
FNV65_RS23940	COG0577	efflux transmembrane transporter activity
FNV65_RS23945	COG1136	(ABC) transporter
FNV65_RS23950	COG0477	Major facilitator Superfamily
FNV65_RS23960	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FNV65_RS23990	COG4585	Histidine kinase
FNV65_RS24005	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FNV65_RS24010	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FNV65_RS24015	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FNV65_RS24020	COG0193	aminoacyl-tRNA hydrolase activity
FNV65_RS24030	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FNV65_RS24040	COG1309	transcriptional regulator
FNV65_RS24050	COG4106	trans-aconitate 2-methyltransferase activity
FNV65_RS24060	COG2197	response regulator
FNV65_RS24070	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FNV65_RS24115	COG0488	(ABC) transporter
FNV65_RS24125	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FNV65_RS24130	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FNV65_RS24140	COG0084	hydrolase, TatD family'
FNV65_RS24170	COG3224	Antibiotic biosynthesis monooxygenase
FNV65_RS24175	COG0590	tRNA wobble adenosine to inosine editing
FNV65_RS24180	COG0768	penicillin binding
FNV65_RS24205	COG0310	cobalt ion transport
FNV65_RS24215	COG1122	ATPase activity
FNV65_RS24220	COG1846	Transcriptional regulator
FNV65_RS24225	COG1764	response to oxidative stress
FNV65_RS24250	COG0667	Aldo Keto reductase
FNV65_RS24260	COG2409	Drug exporters of the RND superfamily
FNV65_RS24270	COG0793	Belongs to the peptidase S41A family
FNV65_RS24270	COG4946	Tricorn protease homolog
FNV65_RS24280	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS24285	COG2267	carboxylic ester hydrolase activity
FNV65_RS24290	COG2072	flavoprotein involved in K transport
FNV65_RS24300	COG0708	Exodeoxyribonuclease III
FNV65_RS24320	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FNV65_RS24325	COG0315	cyclic pyranopterin monophosphate synthase activity
FNV65_RS24325	COG0521	Mo-molybdopterin cofactor biosynthetic process
FNV65_RS24330	COG0315	cyclic pyranopterin monophosphate synthase activity
FNV65_RS24340	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FNV65_RS24345	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FNV65_RS24355	COG3263	regulation of cellular component size
FNV65_RS24375	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FNV65_RS24385	COG1970	mechanosensitive ion channel activity
FNV65_RS24405	COG1376	ErfK ybiS ycfS ynhG family protein
FNV65_RS24420	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FNV65_RS24420	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FNV65_RS24420	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FNV65_RS24430	COG1349	DNA-binding transcription factor activity
FNV65_RS24440	COG0477	Major facilitator Superfamily
FNV65_RS24460	COG1247	-acetyltransferase
FNV65_RS24465	COG3384	dioxygenase
FNV65_RS24470	COG1846	Transcriptional regulator
FNV65_RS24495	COG1414	Transcriptional regulator
FNV65_RS24500	COG0477	Major facilitator Superfamily
FNV65_RS24555	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FNV65_RS24575	COG2197	response regulator
FNV65_RS24580	COG4585	Histidine kinase
FNV65_RS24635	COG2843	Capsule synthesis protein
FNV65_RS24640	COG2197	response regulator
FNV65_RS24670	COG2197	response regulator
FNV65_RS24675	COG4585	Histidine kinase
FNV65_RS24700	COG0277	FAD linked oxidase domain protein
FNV65_RS24710	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FNV65_RS24720	COG2188	Transcriptional regulator
FNV65_RS24745	COG0386	Belongs to the glutathione peroxidase family
FNV65_RS24760	COG1686	Belongs to the peptidase S11 family
FNV65_RS24815	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FNV65_RS24835	COG1733	regulation of RNA biosynthetic process
FNV65_RS24845	COG4221	oxidoreductase activity
FNV65_RS24850	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS24855	COG2267	carboxylic ester hydrolase activity
FNV65_RS24885	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FNV65_RS24910	COG3629	intracellular signal transduction
FNV65_RS24910	COG3903	Transcriptional regulator
FNV65_RS24925	COG0318	PFAM AMP-dependent synthetase and ligase
FNV65_RS24940	COG1024	Enoyl-CoA hydratase
FNV65_RS24945	COG0515	serine threonine protein kinase
FNV65_RS24945	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FNV65_RS24965	COG1960	acyl-CoA dehydrogenase activity
FNV65_RS24975	COG2226	methyltransferase
FNV65_RS24980	COG0259	pyridoxamine-phosphate oxidase activity
FNV65_RS25030	COG1024	Enoyl-CoA hydratase
FNV65_RS25035	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FNV65_RS25055	COG1960	acyl-CoA dehydrogenase activity
FNV65_RS25060	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS25080	COG1960	acyl-CoA dehydrogenase activity
FNV65_RS25085	COG1960	acyl-CoA dehydrogenase activity
FNV65_RS25095	COG0318	PFAM AMP-dependent synthetase and ligase
FNV65_RS25110	COG1595	DNA-templated transcription, initiation
FNV65_RS25160	COG2267	carboxylic ester hydrolase activity
FNV65_RS25170	COG4821	SIS domain
FNV65_RS25195	COG0259	pyridoxamine-phosphate oxidase activity
FNV65_RS25205	COG1024	Enoyl-CoA hydratase
FNV65_RS25210	COG0318	PFAM AMP-dependent synthetase and ligase
FNV65_RS25225	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FNV65_RS25260	COG1132	(ABC) transporter
FNV65_RS25265	COG0277	FAD linked oxidase domain protein
FNV65_RS25265	COG0247	lactate metabolic process
FNV65_RS25290	COG2124	cytochrome p450
FNV65_RS25300	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FNV65_RS25320	COG0789	Transcriptional regulator
FNV65_RS25330	COG0667	Aldo Keto reductase
FNV65_RS25345	COG1846	Transcriptional regulator
FNV65_RS25355	COG2252	PERMEase
FNV65_RS25365	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FNV65_RS25395	COG2814	Major facilitator Superfamily
FNV65_RS25405	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FNV65_RS25410	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FNV65_RS25415	COG1278	Cold shock
FNV65_RS25440	COG1061	Type III restriction enzyme res subunit
FNV65_RS25455	COG3973	AAA domain
FNV65_RS25460	COG3142	Participates in the control of copper homeostasis
FNV65_RS25495	COG1737	Transcriptional regulator
FNV65_RS25500	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FNV65_RS25505	COG1263	PTS System
FNV65_RS25505	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FNV65_RS25545	COG2084	Dehydrogenase
FNV65_RS25560	COG0459	protein refolding
FNV65_RS25580	COG0463	Glycosyl transferase, family 2
FNV65_RS25635	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FNV65_RS25675	COG0308	aminopeptidase N
FNV65_RS25705	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNV65_RS25705	COG0723	plastoquinol--plastocyanin reductase activity
FNV65_RS25755	COG3842	ATPase activity
FNV65_RS25775	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FNV65_RS25780	COG0215	cysteine-tRNA ligase activity
FNV65_RS25785	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FNV65_RS25790	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FNV65_RS25795	COG1329	Transcriptional regulator
FNV65_RS25815	COG5002	protein histidine kinase activity
FNV65_RS25850	COG0222	ribosome binding
FNV65_RS25855	COG0588	phosphoglycerate mutase activity
FNV65_RS25885	COG0438	transferase activity, transferring glycosyl groups
FNV65_RS25920	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FNV65_RS25925	COG1090	epimerase
FNV65_RS25930	COG1595	DNA-templated transcription, initiation
FNV65_RS25940	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS25950	COG1309	transcriptional regulator
FNV65_RS25955	COG1063	alcohol dehydrogenase
FNV65_RS25980	COG2188	Transcriptional regulator
FNV65_RS25990	COG2188	Transcriptional regulator
FNV65_RS26000	COG4552	Acetyltransferase involved in intracellular survival and related
FNV65_RS26015	COG1490	D-aminoacyl-tRNA deacylase activity
FNV65_RS26020	COG0354	folic acid binding
FNV65_RS26030	COG3485	protocatechuate 3,4-dioxygenase
FNV65_RS26070	COG2897	thiosulfate sulfurtransferase activity
FNV65_RS26100	COG0745	RESPONSE REGULATOR receiver
FNV65_RS26105	COG1609	Transcriptional regulator
FNV65_RS26140	COG0745	RESPONSE REGULATOR receiver
FNV65_RS26145	COG1132	(ABC) transporter
FNV65_RS26150	COG0737	Belongs to the 5'-nucleotidase family
FNV65_RS26155	COG0456	acetyltransferase
FNV65_RS26170	COG1131	(ABC) transporter
FNV65_RS26185	COG1725	Transcriptional regulator
FNV65_RS26190	COG1131	(ABC) transporter
FNV65_RS26205	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FNV65_RS26215	COG0494	nUDIX hydrolase
FNV65_RS26215	COG0406	alpha-ribazole phosphatase activity
FNV65_RS26235	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FNV65_RS26240	COG0306	phosphate transporter
FNV65_RS26250	COG1937	Protein conserved in bacteria
FNV65_RS26265	COG0277	FAD linked oxidase domain protein
FNV65_RS26270	COG0671	phosphoesterase, PA-phosphatase related
FNV65_RS26275	COG1196	nuclear chromosome segregation
FNV65_RS26275	COG0741	lytic transglycosylase activity
FNV65_RS26275	COG0739	heme binding
FNV65_RS26385	COG1252	NADH dehydrogenase
FNV65_RS26395	COG0366	Alpha amylase catalytic
FNV65_RS26395	COG1470	cell adhesion involved in biofilm formation
FNV65_RS26415	COG0579	oxidoreductase
FNV65_RS26420	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FNV65_RS26430	COG0667	Aldo Keto reductase
FNV65_RS26455	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FNV65_RS26455	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FNV65_RS26465	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FNV65_RS26485	COG0513	Belongs to the DEAD box helicase family
FNV65_RS26525	COG1643	Atp-dependent helicase
FNV65_RS26560	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FNV65_RS26580	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FNV65_RS26585	COG0047	phosphoribosylformylglycinamidine synthase activity
FNV65_RS26590	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FNV65_RS26620	COG3850	Histidine kinase
FNV65_RS26625	COG2197	response regulator
FNV65_RS26635	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FNV65_RS26650	COG0151	Belongs to the GarS family
FNV65_RS26735	COG0433	COG0433 Predicted ATPase
FNV65_RS26750	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FNV65_RS26785	COG1191	sigma factor activity
FNV65_RS26790	COG1191	sigma factor activity
FNV65_RS26820	COG3467	pyridoxamine 5'-phosphate
FNV65_RS26830	COG0477	Major facilitator Superfamily
FNV65_RS26835	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FNV65_RS26845	COG2205	protein histidine kinase activity
FNV65_RS26850	COG0745	RESPONSE REGULATOR receiver
FNV65_RS26860	COG2329	Antibiotic biosynthesis monooxygenase
FNV65_RS26875	COG1846	Transcriptional regulator
FNV65_RS26920	COG0318	PFAM AMP-dependent synthetase and ligase
FNV65_RS26925	COG1595	DNA-templated transcription, initiation
FNV65_RS26940	COG1960	acyl-CoA dehydrogenase activity
FNV65_RS26950	COG1960	acyl-CoA dehydrogenase activity
FNV65_RS26990	COG0494	nUDIX hydrolase
FNV65_RS27015	COG2188	Transcriptional regulator
FNV65_RS27055	COG2318	DinB family
FNV65_RS27085	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FNV65_RS27105	COG0653	protein targeting
FNV65_RS27125	COG0006	proline dipeptidase activity
FNV65_RS27140	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
FNV65_RS27160	COG2409	Drug exporters of the RND superfamily
FNV65_RS27165	COG4585	Histidine kinase
FNV65_RS27200	COG2837	iron assimilation
FNV65_RS27210	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FNV65_RS27215	COG0561	phosphatase activity
FNV65_RS27245	COG1131	(ABC) transporter
FNV65_RS27255	COG0789	Transcriptional regulator
FNV65_RS27260	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
FNV65_RS27270	COG0561	phosphatase activity
FNV65_RS27280	COG4988	ABC transporter
FNV65_RS27285	COG1294	oxidase, subunit
FNV65_RS27290	COG1271	oxidase subunit
FNV65_RS27295	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FNV65_RS27300	COG1609	Transcriptional regulator
FNV65_RS27320	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FNV65_RS27345	COG0662	Cupin 2, conserved barrel domain protein
FNV65_RS27350	COG1950	PFAM Membrane protein of
FNV65_RS27355	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FNV65_RS27360	COG0626	cystathionine gamma-synthase activity
FNV65_RS27395	COG2814	Major facilitator Superfamily
FNV65_RS27415	COG0305	Participates in initiation and elongation during chromosome replication
FNV65_RS27430	COG0359	binds to the 23S rRNA
FNV65_RS27435	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FNV65_RS27440	COG0629	single-stranded DNA binding
FNV65_RS27445	COG0360	Binds together with S18 to 16S ribosomal RNA
FNV65_RS27470	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FNV65_RS27495	COG0617	tRNA 3'-terminal CCA addition
FNV65_RS27515	COG1595	DNA-templated transcription, initiation
FNV65_RS27525	COG0492	ferredoxin-NADP+ reductase activity
FNV65_RS27530	COG3118	belongs to the thioredoxin family
FNV65_RS27545	COG1192	Involved in chromosome partitioning
FNV65_RS27550	COG0357	Ribosomal RNA small subunit methyltransferase G
FNV65_RS27560	COG0706	membrane insertase activity
FNV65_RS27565	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FNV65_RS27570	COG0594	ribonuclease P activity
FNV65_RS27575	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FNV65_RS27580	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FNV65_RS27590	COG0592	DNA-directed DNA polymerase activity
FNV65_RS27595	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FNV65_RS27600	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FNV65_RS27605	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
FNV65_RS27610	COG0187	DNA topoisomerase II activity
FNV65_RS27615	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FNV65_RS27650	COG0515	serine threonine protein kinase
FNV65_RS27675	COG0705	Rhomboid family
FNV65_RS27690	COG3764	Sortase (surface protein transpeptidase)
FNV65_RS27705	COG3764	Sortase (surface protein transpeptidase)
FNV65_RS27710	COG3764	Sortase (surface protein transpeptidase)
FNV65_RS27715	COG0515	serine threonine protein kinase
FNV65_RS27725	COG0768	penicillin binding
FNV65_RS27740	COG1716	ATPase activity
FNV65_RS27745	COG1716	ATPase activity
FNV65_RS27770	COG0745	RESPONSE REGULATOR receiver
FNV65_RS27785	COG4770	biotin carboxylase activity
FNV65_RS27800	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FNV65_RS27845	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FNV65_RS27875	COG0475	glutathione-regulated potassium exporter activity
FNV65_RS27885	COG1733	regulation of RNA biosynthetic process
FNV65_RS27890	COG0477	Major facilitator Superfamily
FNV65_RS27910	COG0277	FAD linked oxidase domain protein
FNV65_RS27925	COG0702	epimerase
FNV65_RS27930	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FNV65_RS27935	COG1733	regulation of RNA biosynthetic process
FNV65_RS27980	COG1250	3-hydroxyacyl-CoA dehydrogenase
FNV65_RS27985	COG1309	transcriptional regulator
FNV65_RS27990	COG1522	sequence-specific DNA binding
FNV65_RS28010	COG0746	molybdenum cofactor guanylyltransferase activity
FNV65_RS28025	COG0604	alcohol dehydrogenase
FNV65_RS28025	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS28025	COG3321	synthase
FNV65_RS28040	COG0515	serine threonine protein kinase
FNV65_RS28045	COG0515	serine threonine protein kinase
FNV65_RS28070	COG0022	dehydrogenase e1 component
FNV65_RS28075	COG0508	dehydrogenase complex catalyzes the overall conversion of
FNV65_RS28130	COG1362	aminopeptidase activity
FNV65_RS28135	COG1960	acyl-CoA dehydrogenase activity
FNV65_RS28145	COG1741	Belongs to the pirin family
FNV65_RS28160	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FNV65_RS28190	COG3866	Pectate lyase
FNV65_RS28200	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FNV65_RS28220	COG1289	transmembrane transporter activity
FNV65_RS28230	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FNV65_RS28235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FNV65_RS28265	COG2205	protein histidine kinase activity
FNV65_RS28270	COG0745	RESPONSE REGULATOR receiver
FNV65_RS28285	COG1653	transport
FNV65_RS28305	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FNV65_RS28315	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FNV65_RS28355	COG1278	Cold shock
FNV65_RS28390	COG0725	ABC transporter, periplasmic molybdate-binding protein
FNV65_RS28440	COG0515	serine threonine protein kinase
FNV65_RS28440	COG2815	serine threonine protein kinase
FNV65_RS28455	COG1595	DNA-templated transcription, initiation
FNV65_RS28465	COG0561	phosphatase activity
FNV65_RS28515	COG0745	RESPONSE REGULATOR receiver
FNV65_RS28520	COG5002	protein histidine kinase activity
FNV65_RS28530	COG2409	Drug exporters of the RND superfamily
FNV65_RS28535	COG4585	Histidine kinase
FNV65_RS28540	COG2197	response regulator
FNV65_RS28560	COG0640	Transcriptional regulator
FNV65_RS28565	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FNV65_RS28575	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FNV65_RS28580	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FNV65_RS28650	COG2326	polyphosphate kinase activity
FNV65_RS28655	COG3387	PFAM Glycoside hydrolase 15-related
FNV65_RS28660	COG0477	Major facilitator Superfamily
FNV65_RS28730	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FNV65_RS28750	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FNV65_RS28750	COG0515	serine threonine protein kinase
FNV65_RS28775	COG1733	regulation of RNA biosynthetic process
FNV65_RS28805	COG2205	protein histidine kinase activity
FNV65_RS28810	COG0745	RESPONSE REGULATOR receiver
FNV65_RS28880	COG0717	Belongs to the dCTP deaminase family
FNV65_RS28905	COG2181	nitrate reductase activity
FNV65_RS28905	COG0247	lactate metabolic process
FNV65_RS28910	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FNV65_RS28915	COG0443	Heat shock 70 kDa protein
FNV65_RS28920	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FNV65_RS28925	COG0484	heat shock protein binding
FNV65_RS28930	COG0789	Transcriptional regulator
FNV65_RS28940	COG4213	ABC transporter substrate-binding protein
FNV65_RS28965	COG1305	Transglutaminase-like
FNV65_RS29010	COG0542	response to heat
FNV65_RS29045	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FNV65_RS29060	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FNV65_RS29065	COG0191	fructose-bisphosphate aldolase activity
FNV65_RS29085	COG3844	kynureninase activity
FNV65_RS29110	COG4585	Histidine kinase
FNV65_RS29115	COG2197	response regulator
FNV65_RS29125	COG2197	response regulator
FNV65_RS29140	COG3559	Exporter of polyketide antibiotics
FNV65_RS29145	COG1131	(ABC) transporter
FNV65_RS29160	COG4303	Ethanolamine ammonia lyase large subunit
FNV65_RS29175	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FNV65_RS29180	COG0737	Belongs to the 5'-nucleotidase family
FNV65_RS29190	COG1802	Transcriptional regulator
FNV65_RS29195	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FNV65_RS29200	COG0693	protein deglycase activity
FNV65_RS29230	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FNV65_RS29235	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FNV65_RS29270	COG5000	phosphorelay sensor kinase activity
FNV65_RS29270	COG5002	protein histidine kinase activity
FNV65_RS29350	COG0515	serine threonine protein kinase
FNV65_RS29395	COG4152	abc transporter atp-binding protein
FNV65_RS29455	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FNV65_RS29470	COG1132	(ABC) transporter
FNV65_RS29495	COG1408	metallophosphoesterase
FNV65_RS29520	COG0003	Pfam Anion-transporting ATPase
FNV65_RS29545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNV65_RS29575	COG0596	Alpha beta hydrolase
FNV65_RS29585	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FNV65_RS29590	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FNV65_RS29595	COG0659	secondary active sulfate transmembrane transporter activity
FNV65_RS29655	COG1205	dead DEAH box helicase
FNV65_RS29655	COG1111	helicase
FNV65_RS29660	COG1366	Belongs to the anti-sigma-factor antagonist family
FNV65_RS29665	COG2172	sigma factor antagonist activity
FNV65_RS29670	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FNV65_RS29685	COG2815	serine threonine protein kinase
FNV65_RS29685	COG0515	serine threonine protein kinase
FNV65_RS29695	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FNV65_RS29695	COG1754	DNA topoisomerase type I activity
FNV65_RS29700	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FNV65_RS29705	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FNV65_RS29835	COG1136	(ABC) transporter
FNV65_RS29845	COG2197	response regulator
FNV65_RS29915	COG3903	Transcriptional regulator
FNV65_RS29915	COG3629	intracellular signal transduction
FNV65_RS29920	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FNV65_RS29920	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FNV65_RS29945	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FNV65_RS29950	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FNV65_RS29955	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FNV65_RS29960	COG0254	rRNA binding
FNV65_RS29970	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FNV65_RS29990	COG1012	belongs to the aldehyde dehydrogenase family
FNV65_RS30010	COG0076	glutamate decarboxylase activity
FNV65_RS30020	COG0789	Transcriptional regulator
FNV65_RS30025	COG0393	Putative heavy-metal-binding
FNV65_RS30040	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FNV65_RS30045	COG2027	D-alanyl-D-alanine carboxypeptidase
FNV65_RS30055	COG0037	tRNA processing
FNV65_RS30070	COG0302	gtp cyclohydrolase
FNV65_RS30085	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FNV65_RS30100	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FNV65_RS30100	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FNV65_RS30125	COG0649	NAD binding
FNV65_RS30145	COG2197	response regulator
FNV65_RS30150	COG1660	Displays ATPase and GTPase activities
FNV65_RS30175	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FNV65_RS30180	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FNV65_RS30190	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FNV65_RS30210	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FNV65_RS30240	COG0739	heme binding
FNV65_RS30260	COG2205	protein histidine kinase activity
FNV65_RS30265	COG0745	RESPONSE REGULATOR receiver
FNV65_RS30275	COG1595	DNA-templated transcription, initiation
FNV65_RS30290	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
FNV65_RS30310	COG0248	Ppx GppA phosphatase
FNV65_RS30315	COG1082	Xylose isomerase domain protein TIM barrel
FNV65_RS30320	COG1309	transcriptional regulator
FNV65_RS30325	COG0129	dihydroxy-acid dehydratase activity
FNV65_RS30330	COG0515	serine threonine protein kinase
FNV65_RS30330	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FNV65_RS30340	COG4991	sh3 domain protein
FNV65_RS30350	COG2226	methyltransferase
FNV65_RS30360	COG1129	ABC transporter
FNV65_RS30360	COG0842	Transport permease protein
FNV65_RS30370	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FNV65_RS30375	COG0180	Tryptophanyl-tRNA synthetase
FNV65_RS30415	COG0123	including yeast histone deacetylase and acetoin utilization protein
FNV65_RS30465	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FNV65_RS30470	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FNV65_RS30475	COG0181	hydroxymethylbilane synthase activity
FNV65_RS30480	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FNV65_RS30480	COG1648	precorrin-2 dehydrogenase activity
FNV65_RS30485	COG0113	porphobilinogen synthase activity
FNV65_RS30515	COG0018	arginyl-trna synthetase
FNV65_RS30520	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
FNV65_RS30540	COG1690	Belongs to the RtcB family
FNV65_RS30560	COG1742	UPF0060 membrane protein
FNV65_RS30570	COG1846	Transcriptional regulator
FNV65_RS30575	COG1733	regulation of RNA biosynthetic process
FNV65_RS30590	COG0583	DNA-binding transcription factor activity
FNV65_RS30605	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV65_RS30635	COG0531	amino acid
FNV65_RS30645	COG1136	(ABC) transporter
FNV65_RS30655	COG2197	response regulator
FNV65_RS30670	COG0501	Belongs to the peptidase M48B family
FNV65_RS30680	COG1968	undecaprenyl-diphosphatase activity
FNV65_RS30705	COG0531	amino acid
FNV65_RS30725	COG0598	Magnesium transport protein CorA
FNV65_RS30730	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FNV65_RS30745	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FNV65_RS30750	COG0406	alpha-ribazole phosphatase activity
FNV65_RS30770	COG1333	cytochrome c biogenesis protein
FNV65_RS30775	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FNV65_RS30820	COG2226	methyltransferase
FNV65_RS30825	COG3321	synthase
FNV65_RS30825	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS30825	COG0604	alcohol dehydrogenase
FNV65_RS30830	COG0640	Transcriptional regulator
FNV65_RS30850	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FNV65_RS30855	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FNV65_RS30860	COG0163	prenyltransferase activity
FNV65_RS30870	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FNV65_RS30885	COG1309	transcriptional regulator
FNV65_RS30900	COG0183	Belongs to the thiolase family
FNV65_RS30910	COG1278	Cold shock
FNV65_RS30915	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FNV65_RS30930	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FNV65_RS30960	COG2226	methyltransferase
FNV65_RS30990	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FNV65_RS30995	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FNV65_RS31000	COG0649	NAD binding
FNV65_RS31010	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FNV65_RS31015	COG1034	ATP synthesis coupled electron transport
FNV65_RS31020	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FNV65_RS31025	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FNV65_RS31035	COG0713	ATP synthesis coupled electron transport
FNV65_RS31040	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FNV65_RS31050	COG1007	ATP synthesis coupled electron transport
FNV65_RS31055	COG0514	ATP-dependent DNA helicase (RecQ)
FNV65_RS31060	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FNV65_RS31065	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FNV65_RS31070	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNV65_RS31085	COG2188	Transcriptional regulator
FNV65_RS31105	COG0492	ferredoxin-NADP+ reductase activity
FNV65_RS31115	COG5280	Phage tail tape measure protein TP901
FNV65_RS31115	COG3953	SLT domain
FNV65_RS31130	COG0142	geranyltranstransferase activity
FNV65_RS31145	COG1131	(ABC) transporter
FNV65_RS31155	COG0655	NAD(P)H dehydrogenase (quinone) activity
FNV65_RS31180	COG0702	epimerase
FNV65_RS31185	COG1733	regulation of RNA biosynthetic process
FNV65_RS31190	COG1013	pyruvate-flavodoxin oxidoreductase activity
FNV65_RS31195	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FNV65_RS31195	COG0674	pyruvate-flavodoxin oxidoreductase activity
FNV65_RS31215	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FNV65_RS31220	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FNV65_RS31225	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FNV65_RS31230	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FNV65_RS31235	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FNV65_RS31240	COG0839	Belongs to the complex I subunit 6 family
FNV65_RS31245	COG0713	ATP synthesis coupled electron transport
FNV65_RS31260	COG1007	ATP synthesis coupled electron transport
FNV65_RS31265	COG0501	Belongs to the peptidase M48B family
FNV65_RS31270	COG3304	Inner membrane component domain
FNV65_RS31290	COG2261	transglycosylase associated protein
FNV65_RS31295	COG1666	GTP binding
FNV65_RS31375	COG2188	Transcriptional regulator
FNV65_RS31400	COG0702	epimerase
FNV65_RS31405	COG0402	S-adenosylhomocysteine deaminase activity
FNV65_RS31420	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FNV65_RS31425	COG2030	dehydratase
FNV65_RS31440	COG0477	Major facilitator Superfamily
FNV65_RS31445	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FNV65_RS31450	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FNV65_RS31465	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FNV65_RS31470	COG0436	Aminotransferase
FNV65_RS31490	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FNV65_RS31495	COG0081	regulation of translation
FNV65_RS31510	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FNV65_RS31515	COG0222	ribosome binding
FNV65_RS31525	COG0085	RNA polymerase activity
FNV65_RS31530	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FNV65_RS31560	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FNV65_RS31565	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FNV65_RS31570	COG0049	tRNA binding
FNV65_RS31575	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FNV65_RS31580	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FNV65_RS31595	COG2124	cytochrome p450
FNV65_RS31615	COG1404	Belongs to the peptidase S8 family
FNV65_RS31650	COG0051	transcription antitermination factor activity, RNA binding
FNV65_RS31655	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FNV65_RS31660	COG0088	Forms part of the polypeptide exit tunnel
FNV65_RS31665	COG0089	rRNA binding
FNV65_RS31670	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FNV65_RS31675	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FNV65_RS31680	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FNV65_RS31685	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FNV65_RS31690	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FNV65_RS31695	COG0255	Belongs to the universal ribosomal protein uL29 family
FNV65_RS31700	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FNV65_RS31705	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FNV65_RS31710	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FNV65_RS31715	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FNV65_RS31720	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FNV65_RS31730	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FNV65_RS31735	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FNV65_RS31740	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FNV65_RS31745	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FNV65_RS31750	COG1841	ribosomal large subunit assembly
FNV65_RS31755	COG0200	Binds to the 23S rRNA
FNV65_RS31765	COG0563	adenylate kinase activity
FNV65_RS31775	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FNV65_RS31780	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FNV65_RS31785	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FNV65_RS31790	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FNV65_RS31795	COG0202	RNA polymerase activity
FNV65_RS31800	COG0203	ribosomal protein L17
FNV65_RS31805	COG0101	tRNA pseudouridine synthase activity
FNV65_RS31815	COG1215	transferase activity, transferring glycosyl groups
FNV65_RS31820	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FNV65_RS31820	COG4124	Belongs to the glycosyl hydrolase 26 family
FNV65_RS31835	COG0463	Glycosyl transferase, family 2
FNV65_RS31845	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FNV65_RS31850	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FNV65_RS31855	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FNV65_RS31860	COG1072	(Pantothenic acid kinase))
FNV65_RS31865	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FNV65_RS31910	COG0736	holo-[acyl-carrier-protein] synthase activity
FNV65_RS31925	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FNV65_RS31935	COG0802	atpase or kinase
FNV65_RS31955	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FNV65_RS31965	COG1609	Transcriptional regulator
FNV65_RS31975	COG1175	transmembrane transport
FNV65_RS31980	COG0395	ABC-type sugar transport system, permease component
FNV65_RS31985	COG1472	Belongs to the glycosyl hydrolase 3 family
FNV65_RS31990	COG1609	Transcriptional regulator
FNV65_RS32015	COG4941	Belongs to the sigma-70 factor family
FNV65_RS32025	COG0726	polysaccharide deacetylase
FNV65_RS32030	COG0726	polysaccharide deacetylase
FNV65_RS32035	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FNV65_RS32040	COG0459	protein refolding
FNV65_RS32050	COG4221	oxidoreductase activity
FNV65_RS32060	COG0583	DNA-binding transcription factor activity
FNV65_RS32075	COG1595	DNA-templated transcription, initiation
FNV65_RS32085	COG0516	GMP reductase activity
FNV65_RS32100	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FNV65_RS32120	COG0515	serine threonine protein kinase
FNV65_RS32125	COG2815	serine threonine protein kinase
FNV65_RS32125	COG0515	serine threonine protein kinase
FNV65_RS32130	COG0515	serine threonine protein kinase
FNV65_RS32135	COG1012	belongs to the aldehyde dehydrogenase family
FNV65_RS32160	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FNV65_RS32160	COG0519	Catalyzes the synthesis of GMP from XMP
FNV65_RS32205	COG2197	response regulator
FNV65_RS32240	COG0739	heme binding
FNV65_RS32250	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FNV65_RS32250	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FNV65_RS32265	COG0714	Associated with various cellular activities
FNV65_RS32270	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FNV65_RS32275	COG3552	Protein containing von Willebrand factor type A (VWA) domain
FNV65_RS32290	COG0045	succinate-CoA ligase (ADP-forming) activity
FNV65_RS32325	COG0138	bifunctional purine biosynthesis protein purh
FNV65_RS32345	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FNV65_RS32370	COG0039	L-malate dehydrogenase activity
FNV65_RS32390	COG0456	acetyltransferase
FNV65_RS32390	COG1846	Transcriptional regulator
FNV65_RS32395	COG1012	belongs to the aldehyde dehydrogenase family
FNV65_RS32405	COG0517	IMP dehydrogenase activity
FNV65_RS32405	COG4175	Glycine betaine
FNV65_RS32410	COG4176	ABC-type proline glycine betaine transport system permease component
FNV65_RS32425	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FNV65_RS32430	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FNV65_RS32440	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FNV65_RS32450	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FNV65_RS32460	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FNV65_RS32465	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FNV65_RS32465	COG0512	Glutamine amidotransferase of anthranilate synthase
FNV65_RS32470	COG3224	Antibiotic biosynthesis monooxygenase
FNV65_RS32490	COG0754	glutathionylspermidine amidase activity
FNV65_RS32495	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FNV65_RS32500	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FNV65_RS32510	COG0180	Tryptophanyl-tRNA synthetase
FNV65_RS32545	COG1295	ribonuclease BN
FNV65_RS32550	COG1686	Belongs to the peptidase S11 family
FNV65_RS32560	COG1408	metallophosphoesterase
FNV65_RS32580	COG2205	protein histidine kinase activity
FNV65_RS32585	COG0745	RESPONSE REGULATOR receiver
FNV65_RS32590	COG2409	Drug exporters of the RND superfamily
FNV65_RS32635	COG1053	succinate dehydrogenase
FNV65_RS32645	COG2009	succinate dehydrogenase
FNV65_RS32655	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FNV65_RS32690	COG1595	DNA-templated transcription, initiation
FNV65_RS32695	COG1595	DNA-templated transcription, initiation
FNV65_RS32710	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FNV65_RS32710	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FNV65_RS32725	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FNV65_RS32735	COG1216	Glycosyl transferase, family 2
FNV65_RS32750	COG2089	acid synthase
FNV65_RS32765	COG0573	inorganic phosphate transmembrane transporter activity
FNV65_RS32800	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FNV65_RS32805	COG4195	phage-related replication protein
FNV65_RS32860	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FNV65_RS32860	COG1473	amidohydrolase
FNV65_RS32865	COG1744	ABC transporter substrate-binding protein PnrA-like
FNV65_RS32870	COG1744	ABC transporter substrate-binding protein PnrA-like
FNV65_RS32875	COG3845	ABC transporter
FNV65_RS32880	COG4603	Belongs to the binding-protein-dependent transport system permease family
FNV65_RS32885	COG1079	Belongs to the binding-protein-dependent transport system permease family
FNV65_RS32915	COG0592	DNA-directed DNA polymerase activity
FNV65_RS32920	COG2814	Major facilitator Superfamily
FNV65_RS32925	COG0583	DNA-binding transcription factor activity
FNV65_RS32935	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FNV65_RS32960	COG2205	protein histidine kinase activity
FNV65_RS32965	COG0745	RESPONSE REGULATOR receiver
FNV65_RS32970	COG1595	DNA-templated transcription, initiation
FNV65_RS32985	COG1012	belongs to the aldehyde dehydrogenase family
FNV65_RS32990	COG1012	belongs to the aldehyde dehydrogenase family
FNV65_RS33050	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FNV65_RS33065	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FNV65_RS33095	COG4770	biotin carboxylase activity
FNV65_RS33105	COG0424	maF-like protein
FNV65_RS33120	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FNV65_RS33130	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FNV65_RS33140	COG1024	Enoyl-CoA hydratase
FNV65_RS33150	COG2986	histidine ammonia-lyase
FNV65_RS33155	COG1278	Cold shock
FNV65_RS33190	COG1136	(ABC) transporter
FNV65_RS33200	COG1404	Belongs to the peptidase S8 family
FNV65_RS33215	COG1064	alcohol dehydrogenase
FNV65_RS33220	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FNV65_RS33225	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FNV65_RS33235	COG2132	Multicopper oxidase
FNV65_RS33275	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FNV65_RS33285	COG3173	Aminoglycoside phosphotransferase
FNV65_RS33310	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FNV65_RS33335	COG2255	four-way junction helicase activity
FNV65_RS33340	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FNV65_RS33385	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FNV65_RS33395	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FNV65_RS33420	COG1331	Highly conserved protein containing a thioredoxin domain
FNV65_RS33450	COG1309	transcriptional regulator
FNV65_RS33455	COG0477	Major facilitator Superfamily
FNV65_RS33465	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
FNV65_RS33565	COG0436	Aminotransferase
FNV65_RS33580	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FNV65_RS33595	COG1414	Transcriptional regulator
FNV65_RS33600	COG0251	oxidation-reduction process
FNV65_RS33605	COG2610	gluconate transmembrane transporter activity
FNV65_RS33665	COG2894	cell division
FNV65_RS33695	COG2197	response regulator
FNV65_RS33715	COG2885	chlorophyll binding
FNV65_RS33720	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FNV65_RS33750	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FNV65_RS33760	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FNV65_RS33775	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FNV65_RS33780	COG0450	alkyl hydroperoxide reductase
FNV65_RS33795	COG1136	(ABC) transporter
FNV65_RS33815	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FNV65_RS33845	COG0114	fumarate hydratase activity
FNV65_RS33865	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FNV65_RS33865	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FNV65_RS33890	COG0778	Nitroreductase
FNV65_RS33895	COG1722	exodeoxyribonuclease VII activity
FNV65_RS33900	COG1570	exodeoxyribonuclease VII activity
FNV65_RS33905	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FNV65_RS33920	COG0012	GTP binding
FNV65_RS34010	COG1053	succinate dehydrogenase
FNV65_RS34030	COG1217	gtp-binding protein TYPA
FNV65_RS34045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNV65_RS34050	COG0444	Belongs to the ABC transporter superfamily
FNV65_RS34055	COG4608	Belongs to the ABC transporter superfamily
FNV65_RS34065	COG0346	lactoylglutathione lyase activity
FNV65_RS34075	COG0601	transmembrane transport
FNV65_RS34080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNV65_RS34085	COG0444	Belongs to the ABC transporter superfamily
FNV65_RS34090	COG4608	Belongs to the ABC transporter superfamily
FNV65_RS34105	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FNV65_RS34125	COG1131	(ABC) transporter
FNV65_RS34135	COG4585	Histidine kinase
FNV65_RS34140	COG2197	response regulator
FNV65_RS34175	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FNV65_RS34185	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FNV65_RS34195	COG0519	Catalyzes the synthesis of GMP from XMP
FNV65_RS34200	COG1024	Enoyl-CoA hydratase
FNV65_RS34215	COG1595	DNA-templated transcription, initiation
FNV65_RS34225	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FNV65_RS34230	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FNV65_RS34255	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FNV65_RS34265	COG0598	Magnesium transport protein CorA
FNV65_RS34275	COG2814	Major facilitator Superfamily
FNV65_RS34290	COG2095	MarC family integral membrane protein
FNV65_RS34300	COG1432	Conserved Protein
FNV65_RS34305	COG0596	Alpha beta hydrolase
FNV65_RS34350	COG0747	negative chemotaxis
FNV65_RS34355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNV65_RS34360	COG0601	transmembrane transport
FNV65_RS34420	COG0210	DNA helicase
FNV65_RS34425	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FNV65_RS34465	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FNV65_RS34520	COG3480	Lon protease (S16) C-terminal proteolytic domain
FNV65_RS34530	COG1615	UPF0182 protein
FNV65_RS34555	COG0753	catalase activity
FNV65_RS34560	COG0517	IMP dehydrogenase activity
FNV65_RS34560	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FNV65_RS34565	COG0483	inositol monophosphate 1-phosphatase activity
FNV65_RS34585	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FNV65_RS34595	COG2135	peptidase activity
FNV65_RS34605	COG1595	DNA-templated transcription, initiation
FNV65_RS34610	COG5662	AntiSigma factor
FNV65_RS34615	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FNV65_RS34615	COG2199	diguanylate cyclase activity
FNV65_RS34630	COG0242	peptide deformylase activity
FNV65_RS34640	COG2124	cytochrome p450
FNV65_RS34660	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FNV65_RS34685	COG2188	Transcriptional regulator
FNV65_RS34690	COG2182	Extracellular solute-binding protein
FNV65_RS34695	COG1175	transmembrane transport
FNV65_RS34700	COG0395	ABC-type sugar transport system, permease component
FNV65_RS34705	COG1472	Belongs to the glycosyl hydrolase 3 family
FNV65_RS34710	COG0363	glucosamine-6-phosphate deaminase activity
FNV65_RS34715	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FNV65_RS34730	COG1597	lipid kinase activity
FNV65_RS34775	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FNV65_RS34780	COG0142	geranyltranstransferase activity
FNV65_RS34850	COG4106	trans-aconitate 2-methyltransferase activity
FNV65_RS34855	COG1126	abc transporter atp-binding protein
FNV65_RS34875	COG0281	malic enzyme
FNV65_RS34880	COG0604	alcohol dehydrogenase
FNV65_RS34915	COG0567	Dehydrogenase, E1 component
FNV65_RS34915	COG0508	dehydrogenase complex catalyzes the overall conversion of
FNV65_RS34920	COG2205	protein histidine kinase activity
FNV65_RS34925	COG0745	RESPONSE REGULATOR receiver
FNV65_RS34955	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FNV65_RS35040	COG0701	Predicted permease
FNV65_RS35045	COG0768	penicillin binding
FNV65_RS35050	COG0772	Belongs to the SEDS family
FNV65_RS35060	COG2205	protein histidine kinase activity
FNV65_RS35085	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FNV65_RS35095	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FNV65_RS35205	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FNV65_RS35340	COG0018	arginyl-trna synthetase
FNV65_RS35345	COG0019	diaminopimelate decarboxylase activity
FNV65_RS35350	COG0460	homoserine dehydrogenase
FNV65_RS35355	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FNV65_RS35360	COG0083	homoserine kinase activity
FNV65_RS35375	COG1316	TRANSCRIPTIONal
FNV65_RS35380	COG0254	rRNA binding
FNV65_RS35385	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FNV65_RS35390	COG2890	protein-(glutamine-N5) methyltransferase activity
FNV65_RS35400	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FNV65_RS35410	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FNV65_RS35415	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FNV65_RS35430	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FNV65_RS35435	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FNV65_RS35440	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FNV65_RS35445	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FNV65_RS35450	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FNV65_RS35455	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FNV65_RS35460	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FNV65_RS35475	COG2197	response regulator
FNV65_RS35500	COG1250	3-hydroxyacyl-CoA dehydrogenase
FNV65_RS35520	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
FNV65_RS35565	COG1131	(ABC) transporter
FNV65_RS35585	COG0183	Belongs to the thiolase family
FNV65_RS35620	COG2814	Major facilitator Superfamily
FNV65_RS35665	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FNV65_RS35665	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FNV65_RS35705	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FNV65_RS35710	COG0857	belongs to the CobB CobQ family
FNV65_RS35710	COG0280	phosphate acetyltransferase
FNV65_RS35715	COG0205	6-phosphofructokinase activity
FNV65_RS35730	COG0395	ABC-type sugar transport system, permease component
FNV65_RS35735	COG1175	transmembrane transport
FNV65_RS35760	COG4565	transcriptional regulatory protein
FNV65_RS35765	COG3290	protein histidine kinase activity
FNV65_RS35770	COG1301	dicarboxylic acid transport
FNV65_RS35780	COG0477	Major facilitator Superfamily
FNV65_RS35795	COG1522	sequence-specific DNA binding
FNV65_RS35815	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FNV65_RS35820	COG3281	Trehalose synthase
FNV65_RS35830	COG0366	Alpha amylase catalytic
FNV65_RS35840	COG0058	SHG alpha-glucan phosphorylase activity
FNV65_RS35860	COG1132	(ABC) transporter
FNV65_RS35865	COG1132	(ABC) transporter
FNV65_RS35870	COG1132	(ABC) transporter
FNV65_RS35875	COG1132	(ABC) transporter
FNV65_RS35880	COG1131	(ABC) transporter
FNV65_RS35890	COG4585	Histidine kinase
FNV65_RS35895	COG2197	response regulator
FNV65_RS35905	COG1376	ErfK ybiS ycfS ynhG family protein
FNV65_RS35910	COG1376	ErfK ybiS ycfS ynhG family protein
FNV65_RS35960	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FNV65_RS35985	COG0475	glutathione-regulated potassium exporter activity
FNV65_RS35990	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FNV65_RS36005	COG3629	intracellular signal transduction
FNV65_RS36005	COG3903	Transcriptional regulator
FNV65_RS36010	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FNV65_RS36035	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FNV65_RS36060	COG2267	carboxylic ester hydrolase activity
FNV65_RS36065	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FNV65_RS36070	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FNV65_RS36075	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FNV65_RS36080	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FNV65_RS36090	COG4122	O-methyltransferase activity
FNV65_RS36095	COG1233	COG1233 Phytoene dehydrogenase and related
FNV65_RS36125	COG3251	PFAM MbtH domain protein
FNV65_RS36130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FNV65_RS36130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FNV65_RS36140	COG0277	FAD linked oxidase domain protein
FNV65_RS36155	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FNV65_RS36160	COG1760	l-serine dehydratase
FNV65_RS36165	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FNV65_RS36170	COG0509	glycine decarboxylation via glycine cleavage system
FNV65_RS36175	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FNV65_RS36195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNV65_RS36210	COG0444	Belongs to the ABC transporter superfamily
FNV65_RS36215	COG4608	Belongs to the ABC transporter superfamily
FNV65_RS36230	COG2860	membrane
FNV65_RS36250	COG2378	regulation of single-species biofilm formation
FNV65_RS36290	COG0482	sulfurtransferase activity
FNV65_RS36300	COG1611	Belongs to the LOG family
FNV65_RS36305	COG4221	oxidoreductase activity
FNV65_RS36315	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FNV65_RS36325	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FNV65_RS36330	COG0154	amidase activity
FNV65_RS36340	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FNV65_RS36345	COG2409	Drug exporters of the RND superfamily
FNV65_RS36350	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FNV65_RS36365	COG2197	response regulator
FNV65_RS36375	COG2133	pyrroloquinoline quinone binding
FNV65_RS36380	COG0667	Aldo Keto reductase
FNV65_RS36390	COG5001	Diguanylate cyclase
FNV65_RS36400	COG0440	acetolactate synthase activity
FNV65_RS36405	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FNV65_RS36415	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FNV65_RS36415	COG1672	PFAM Archaeal ATPase
FNV65_RS36420	COG0477	Major facilitator Superfamily
FNV65_RS36440	COG3214	Protein conserved in bacteria
FNV65_RS36450	COG0506	proline dehydrogenase activity
FNV65_RS36455	COG1012	belongs to the aldehyde dehydrogenase family
FNV65_RS36470	COG1082	Xylose isomerase domain protein TIM barrel
FNV65_RS36480	COG0477	Major facilitator Superfamily
FNV65_RS36495	COG0473	3-isopropylmalate dehydrogenase activity
FNV65_RS36500	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FNV65_RS36520	COG0831	urea catabolic process
FNV65_RS36520	COG0832	Belongs to the urease beta subunit family
FNV65_RS36525	COG0804	urea catabolic process
FNV65_RS36530	COG2957	Belongs to the agmatine deiminase family
FNV65_RS36540	COG0477	Major facilitator Superfamily
FNV65_RS36545	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FNV65_RS36575	COG2197	response regulator
FNV65_RS36585	COG1131	(ABC) transporter
FNV65_RS36620	COG4585	Histidine kinase
FNV65_RS36630	COG2353	YceI-like domain
FNV65_RS36635	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FNV65_RS36655	COG2018	Roadblock/LC7 domain
FNV65_RS36675	COG2018	Roadblock/LC7 domain
FNV65_RS36680	COG5002	protein histidine kinase activity
FNV65_RS36690	COG0179	Fumarylacetoacetate (FAA) hydrolase
FNV65_RS36695	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FNV65_RS36745	COG1414	Transcriptional regulator
FNV65_RS36750	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FNV65_RS36755	COG0066	3-isopropylmalate dehydratase activity
FNV65_RS36765	COG0776	regulation of translation
FNV65_RS36775	COG1920	GTP binding
FNV65_RS36785	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FNV65_RS36790	COG1181	Belongs to the D-alanine--D-alanine ligase family
FNV65_RS36815	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FNV65_RS36820	COG1461	Dihydroxyacetone kinase
FNV65_RS36830	COG0326	Molecular chaperone. Has ATPase activity
FNV65_RS36840	COG0742	ribosomal rna small subunit methyltransferase
FNV65_RS36845	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FNV65_RS36860	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FNV65_RS36865	COG0571	ribonuclease III activity
FNV65_RS36870	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FNV65_RS36875	COG1733	regulation of RNA biosynthetic process
FNV65_RS36890	COG2815	serine threonine protein kinase
FNV65_RS36890	COG0515	serine threonine protein kinase
FNV65_RS36910	COG2340	Cysteine-rich secretory protein family
FNV65_RS36915	COG1254	Belongs to the acylphosphatase family
FNV65_RS36930	COG0477	Major facilitator Superfamily
FNV65_RS36970	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FNV65_RS36980	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FNV65_RS36990	COG0442	prolyl-tRNA aminoacylation
FNV65_RS37000	COG0228	four-way junction DNA binding
FNV65_RS37005	COG1837	Belongs to the UPF0109 family
FNV65_RS37010	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FNV65_RS37015	COG0336	Belongs to the RNA methyltransferase TrmD family
FNV65_RS37020	COG0335	large ribosomal subunit rRNA binding
FNV65_RS37030	COG0681	Belongs to the peptidase S26 family
FNV65_RS37045	COG1051	belongs to the nudix hydrolase family
FNV65_RS37055	COG0792	nuclease activity
FNV65_RS37070	COG1191	sigma factor activity
FNV65_RS37085	COG0052	Belongs to the universal ribosomal protein uS2 family
FNV65_RS37090	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FNV65_RS37095	COG0528	UMP kinase activity
FNV65_RS37100	COG0233	cytoplasmic translational termination
FNV65_RS37105	COG0575	Belongs to the CDS family
FNV65_RS37120	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FNV65_RS37150	COG1674	ftsk spoiiie
FNV65_RS37150	COG0531	amino acid
FNV65_RS37185	COG2188	Transcriptional regulator
FNV65_RS37190	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FNV65_RS37240	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FNV65_RS37250	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FNV65_RS37255	COG3842	ATPase activity
FNV65_RS37285	COG1136	(ABC) transporter
FNV65_RS37290	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FNV65_RS37300	COG1012	belongs to the aldehyde dehydrogenase family
FNV65_RS37340	COG0477	Major facilitator Superfamily
FNV65_RS37365	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FNV65_RS37390	COG3842	ATPase activity
FNV65_RS37395	COG1176	ABC-type spermidine putrescine transport system, permease component I
FNV65_RS37400	COG1177	transmembrane transport
FNV65_RS37405	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNV65_RS37435	COG2508	Transcriptional regulator
FNV65_RS37435	COG2508	Transcriptional regulator
FNV65_RS37440	COG1012	belongs to the aldehyde dehydrogenase family
FNV65_RS37445	COG1472	Belongs to the glycosyl hydrolase 3 family
FNV65_RS37450	COG1653	transport
FNV65_RS37455	COG4209	transmembrane transport
FNV65_RS37460	COG0395	ABC-type sugar transport system, permease component
FNV65_RS37500	COG5297	Belongs to the glycosyl hydrolase family 6
FNV65_RS37515	COG0653	protein targeting
FNV65_RS37525	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FNV65_RS37530	COG0750	zinc metalloprotease
FNV65_RS37535	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FNV65_RS37550	COG0442	prolyl-tRNA aminoacylation
FNV65_RS37570	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FNV65_RS37595	COG0779	Required for maturation of 30S ribosomal subunits
FNV65_RS37610	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FNV65_RS37620	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FNV65_RS37625	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FNV65_RS37650	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNV65_RS37655	COG0601	transmembrane transport
FNV65_RS37665	COG0455	bacterial-type flagellum organization
FNV65_RS37685	COG1404	Belongs to the peptidase S8 family
FNV65_RS37760	COG1674	ftsk spoiiie
FNV65_RS37775	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FNV65_RS37780	COG1185	polyribonucleotide nucleotidyltransferase activity
FNV65_RS37785	COG0612	Peptidase, M16
FNV65_RS37790	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FNV65_RS37810	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
FNV65_RS37815	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FNV65_RS37820	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FNV65_RS37850	COG2770	Histidine kinase
FNV65_RS37850	COG2208	phosphoserine phosphatase activity
FNV65_RS37870	COG1674	ftsk spoiiie
FNV65_RS37880	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FNV65_RS37890	COG1058	Belongs to the CinA family
FNV65_RS37890	COG1546	Belongs to the CinA family
FNV65_RS37895	COG1396	sequence-specific DNA binding
FNV65_RS37900	COG0783	Belongs to the Dps family
FNV65_RS37910	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS37915	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FNV65_RS37920	COG1201	RNA secondary structure unwinding
FNV65_RS37950	COG0628	permease
FNV65_RS37960	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FNV65_RS37980	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FNV65_RS37990	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FNV65_RS37995	COG0765	amino acid transport
FNV65_RS38000	COG0765	amino acid transport
FNV65_RS38005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNV65_RS38010	COG1126	abc transporter atp-binding protein
FNV65_RS38015	COG0745	RESPONSE REGULATOR receiver
FNV65_RS38020	COG2205	protein histidine kinase activity
FNV65_RS38050	COG2197	response regulator
FNV65_RS38080	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FNV65_RS38090	COG3547	Transposase (IS116 IS110 IS902 family)
FNV65_RS38105	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FNV65_RS38115	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FNV65_RS38120	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FNV65_RS38130	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FNV65_RS38170	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FNV65_RS38175	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FNV65_RS38180	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FNV65_RS38215	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FNV65_RS38255	COG1802	Transcriptional regulator
FNV65_RS38260	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FNV65_RS38275	COG0187	DNA topoisomerase II activity
FNV65_RS38290	COG2197	response regulator
FNV65_RS38300	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FNV65_RS38305	COG4565	transcriptional regulatory protein
FNV65_RS38315	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNV65_RS38325	COG4565	transcriptional regulatory protein
FNV65_RS38330	COG3290	protein histidine kinase activity
FNV65_RS38345	COG0372	Belongs to the citrate synthase family
FNV65_RS38365	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FNV65_RS38370	COG0612	Peptidase, M16
FNV65_RS38385	COG1802	Transcriptional regulator
FNV65_RS38390	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FNV65_RS38400	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FNV65_RS38400	COG1042	CoA-binding domain protein
FNV65_RS38400	COG0045	succinate-CoA ligase (ADP-forming) activity
FNV65_RS38415	COG1435	thymidine kinase activity
FNV65_RS38450	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FNV65_RS38460	COG0745	RESPONSE REGULATOR receiver
FNV65_RS38465	COG2205	protein histidine kinase activity
FNV65_RS38490	COG0756	dUTP diphosphatase activity
FNV65_RS38505	COG1136	(ABC) transporter
FNV65_RS38535	COG0569	domain protein
FNV65_RS38540	COG0531	amino acid
FNV65_RS38545	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FNV65_RS38605	COG4585	Histidine kinase
FNV65_RS38610	COG2409	Drug exporters of the RND superfamily
FNV65_RS38625	COG0243	molybdopterin cofactor binding
FNV65_RS38630	COG1799	cell septum assembly
FNV65_RS38660	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FNV65_RS38675	COG2235	arginine
FNV65_RS38680	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FNV65_RS38685	COG0531	amino acid
FNV65_RS38695	COG1024	Enoyl-CoA hydratase
FNV65_RS38740	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FNV65_RS38760	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FNV65_RS38770	COG1404	Belongs to the peptidase S8 family
FNV65_RS38780	COG0745	RESPONSE REGULATOR receiver
FNV65_RS38785	COG2205	protein histidine kinase activity
FNV65_RS38800	COG3537	Alpha-1,2-mannosidase
FNV65_RS38810	COG1653	transport
FNV65_RS38815	COG1175	transmembrane transport
FNV65_RS38820	COG0395	ABC-type sugar transport system, permease component
FNV65_RS38825	COG1940	carbohydrate kinase activity
FNV65_RS38830	COG4213	ABC transporter substrate-binding protein
FNV65_RS38840	COG4214	carbohydrate transport
FNV65_RS38845	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FNV65_RS38850	COG0531	amino acid
FNV65_RS38885	COG1250	3-hydroxyacyl-CoA dehydrogenase
FNV65_RS38885	COG1024	Enoyl-CoA hydratase
FNV65_RS38890	COG0183	Belongs to the thiolase family
FNV65_RS38900	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FNV65_RS38915	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FNV65_RS38930	COG0446	pyridine nucleotide-disulphide oxidoreductase
FNV65_RS38940	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FNV65_RS38945	COG3253	May function as heme-dependent peroxidase
FNV65_RS38965	COG3220	belongs to the UPF0276 family
FNV65_RS39000	COG2326	polyphosphate kinase activity
FNV65_RS39005	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FNV65_RS39045	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FNV65_RS39050	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FNV65_RS39060	COG0515	serine threonine protein kinase
FNV65_RS39095	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
FNV65_RS39140	COG3437	response regulator, receiver
FNV65_RS39140	COG4999	Histidine kinase
FNV65_RS39140	COG3850	Histidine kinase
FNV65_RS39140	COG2205	protein histidine kinase activity
FNV65_RS39165	COG0154	amidase activity
FNV65_RS39180	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FNV65_RS39205	COG0642	Histidine kinase
FNV65_RS39300	COG0504	CTP synthase activity
FNV65_RS39315	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FNV65_RS39440	COG0667	Aldo Keto reductase
FNV65_RS39460	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FNV65_RS39475	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNV65_RS39480	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FNV65_RS39505	COG0529	Catalyzes the synthesis of activated sulfate
FNV65_RS39510	COG0175	sulfate reduction
FNV65_RS39540	COG1960	acyl-CoA dehydrogenase activity
FNV65_RS39555	COG4977	sequence-specific DNA binding
FNV65_RS39555	COG1917	Cupin 2, conserved barrel domain protein
FNV65_RS39585	COG1609	Transcriptional regulator
FNV65_RS39615	COG0154	amidase activity
FNV65_RS39625	COG2040	homocysteine
FNV65_RS39680	COG2340	Cysteine-rich secretory protein family
FNV65_RS39685	COG0596	Alpha beta hydrolase
FNV65_RS39690	COG1309	transcriptional regulator
FNV65_RS39765	COG1131	(ABC) transporter
FNV65_RS39785	COG1175	transmembrane transport
FNV65_RS39800	COG0277	FAD linked oxidase domain protein
FNV65_RS39875	COG1162	GTPase activity
FNV65_RS39915	COG0028	Belongs to the TPP enzyme family
FNV65_RS39935	COG1802	Transcriptional regulator
FNV65_RS39965	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FNV65_RS39970	COG2252	PERMEase
FNV65_RS40000	COG0726	polysaccharide deacetylase
FNV65_RS40005	COG0673	inositol 2-dehydrogenase activity
FNV65_RS40015	COG1132	(ABC) transporter
FNV65_RS40025	COG0596	Alpha beta hydrolase
FNV65_RS40030	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FNV65_RS40050	COG1477	protein flavinylation
FNV65_RS40065	COG0745	RESPONSE REGULATOR receiver
FNV65_RS40070	COG2205	protein histidine kinase activity
FNV65_RS40090	COG3903	Transcriptional regulator
FNV65_RS40090	COG3629	intracellular signal transduction
FNV65_RS40100	COG3903	Transcriptional regulator
FNV65_RS40100	COG3629	intracellular signal transduction
FNV65_RS40115	COG4977	sequence-specific DNA binding
FNV65_RS40150	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FNV65_RS40165	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FNV65_RS40170	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FNV65_RS40245	COG0673	inositol 2-dehydrogenase activity
FNV65_RS40250	COG0667	Aldo Keto reductase
FNV65_RS40300	COG2267	carboxylic ester hydrolase activity
FNV65_RS40320	COG0598	Magnesium transport protein CorA
FNV65_RS40335	COG0583	DNA-binding transcription factor activity
FNV65_RS40355	COG2197	response regulator
FNV65_RS40360	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FNV65_RS40365	COG0318	PFAM AMP-dependent synthetase and ligase
FNV65_RS40375	COG3960	tartronate-semialdehyde synthase activity
FNV65_RS40385	COG0753	catalase activity
FNV65_RS40390	COG2084	Dehydrogenase
FNV65_RS40395	COG3622	Belongs to the hyi family
FNV65_RS40415	COG2351	hydroxyisourate hydrolase activity
FNV65_RS40430	COG2233	PERMEase
FNV65_RS40445	COG1733	regulation of RNA biosynthetic process
FNV65_RS40460	COG0406	alpha-ribazole phosphatase activity
FNV65_RS40465	COG0436	Aminotransferase
FNV65_RS40485	COG2304	oxidoreductase activity
FNV65_RS40490	COG4264	IucA IucC family
FNV65_RS40500	COG0515	serine threonine protein kinase
FNV65_RS40500	COG2815	serine threonine protein kinase
FNV65_RS40520	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FNV65_RS40525	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FNV65_RS40535	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FNV65_RS40550	COG1414	Transcriptional regulator
FNV65_RS40555	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FNV65_RS40560	COG4266	Belongs to the allantoicase family
FNV65_RS40565	COG0598	Magnesium transport protein CorA
FNV65_RS40580	COG0667	Aldo Keto reductase
FNV65_RS40585	COG2197	response regulator
FNV65_RS40595	COG0673	inositol 2-dehydrogenase activity
FNV65_RS40600	COG2188	Transcriptional regulator
FNV65_RS40625	COG1940	carbohydrate kinase activity
FNV65_RS40635	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FNV65_RS40710	COG0640	Transcriptional regulator
FNV65_RS40795	COG0396	ATPase activity
FNV65_RS40810	COG0443	Heat shock 70 kDa protein
FNV65_RS40815	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FNV65_RS40820	COG0484	heat shock protein binding
FNV65_RS40830	COG0542	response to heat
FNV65_RS40845	COG3634	alkyl hydroperoxide reductase activity
FNV65_RS40870	COG2826	transposase and inactivated derivatives, IS30 family
FNV65_RS41105	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FNV65_RS41125	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FNV65_RS41135	COG1621	beta-fructofuranosidase activity
FNV65_RS41140	COG1609	Transcriptional regulator
FNV65_RS41145	COG1653	transport
FNV65_RS41150	COG1175	transmembrane transport
FNV65_RS41155	COG0395	ABC-type sugar transport system, permease component
FNV65_RS41160	COG1621	beta-fructofuranosidase activity
FNV65_RS41170	COG2267	carboxylic ester hydrolase activity
FNV65_RS41185	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS41200	COG1511	domain protein
FNV65_RS41210	COG0321	lipoyl(octanoyl) transferase activity
FNV65_RS41235	COG2409	Drug exporters of the RND superfamily
FNV65_RS41245	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FNV65_RS41265	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS41310	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNV65_RS41350	COG4221	oxidoreductase activity
FNV65_RS41410	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FNV65_RS41415	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FNV65_RS41430	COG1126	abc transporter atp-binding protein
FNV65_RS41440	COG0765	amino acid transport
FNV65_RS41445	COG0765	amino acid transport
FNV65_RS41460	COG0405	Gamma-glutamyltransferase
FNV65_RS41500	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FNV65_RS41510	COG1953	Uracil, thiamine, allantoin
FNV65_RS41520	COG2226	methyltransferase
FNV65_RS41530	COG3851	Histidine kinase
FNV65_RS41535	COG2197	response regulator
FNV65_RS41550	COG0483	inositol monophosphate 1-phosphatase activity
FNV65_RS41565	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FNV65_RS41575	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FNV65_RS41580	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FNV65_RS41590	COG1215	transferase activity, transferring glycosyl groups
FNV65_RS41600	COG4310	Domain of unknown function (DUF2172)
FNV65_RS41615	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FNV65_RS41625	COG0438	transferase activity, transferring glycosyl groups
FNV65_RS41650	COG0367	asparagine synthase
FNV65_RS41670	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FNV65_RS41690	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS41695	COG0583	DNA-binding transcription factor activity
FNV65_RS41705	COG0477	Major facilitator Superfamily
FNV65_RS41720	COG1309	transcriptional regulator
FNV65_RS41775	COG1136	(ABC) transporter
FNV65_RS41785	COG2205	protein histidine kinase activity
FNV65_RS41790	COG2205	protein histidine kinase activity
FNV65_RS41800	COG0671	phosphoesterase, PA-phosphatase related
FNV65_RS41820	COG0640	Transcriptional regulator
FNV65_RS41840	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FNV65_RS41890	COG2130	NADP-dependent
FNV65_RS41895	COG0789	Transcriptional regulator
FNV65_RS41900	COG1192	Involved in chromosome partitioning
FNV65_RS41930	COG1929	Belongs to the glycerate kinase type-1 family
FNV65_RS41940	COG0688	phosphatidylethanolamine metabolic process
FNV65_RS41945	COG1960	acyl-CoA dehydrogenase activity
FNV65_RS41955	COG2301	Belongs to the HpcH HpaI aldolase family
FNV65_RS41960	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FNV65_RS41960	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FNV65_RS41965	COG0604	alcohol dehydrogenase
FNV65_RS41975	COG1250	3-hydroxyacyl-CoA dehydrogenase
FNV65_RS41985	COG0456	acetyltransferase
FNV65_RS41985	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FNV65_RS41995	COG0596	Alpha beta hydrolase
FNV65_RS42015	COG2172	sigma factor antagonist activity
FNV65_RS42015	COG1366	Belongs to the anti-sigma-factor antagonist family
FNV65_RS42015	COG2208	phosphoserine phosphatase activity
FNV65_RS42020	COG2226	methyltransferase
FNV65_RS42060	COG2362	D-Aminopeptidase
FNV65_RS42065	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FNV65_RS42075	COG1619	proteins homologs of microcin C7 resistance protein MccF
FNV65_RS42105	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FNV65_RS42110	COG2226	methyltransferase
FNV65_RS42120	COG0488	(ABC) transporter
FNV65_RS42130	COG0693	protein deglycase activity
FNV65_RS42210	COG0443	Heat shock 70 kDa protein
FNV65_RS42225	COG2154	pterin-4-alpha-carbinolamine dehydratase
FNV65_RS42230	COG2226	methyltransferase
FNV65_RS42245	COG2378	regulation of single-species biofilm formation
FNV65_RS42250	COG3401	FG-GAP repeat protein
FNV65_RS42260	COG5297	Belongs to the glycosyl hydrolase family 6
FNV65_RS42260	COG4733	cellulase activity
FNV65_RS42265	COG5297	Belongs to the glycosyl hydrolase family 6
FNV65_RS42270	COG5297	Belongs to the glycosyl hydrolase family 6
FNV65_RS42290	COG4249	Peptidase C14 caspase catalytic subunit p20
FNV65_RS42290	COG2319	Wd-40 repeat
FNV65_RS42295	COG4221	oxidoreductase activity
FNV65_RS42305	COG0656	L-ascorbic acid biosynthetic process
FNV65_RS42330	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FNV65_RS42340	COG3469	chitinase activity
FNV65_RS42345	COG3250	beta-galactosidase activity
FNV65_RS42355	COG0477	Major facilitator Superfamily
FNV65_RS42390	COG1846	Transcriptional regulator
FNV65_RS42395	COG1335	isochorismatase
FNV65_RS42405	COG0583	DNA-binding transcription factor activity
FNV65_RS42410	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FNV65_RS42425	COG3383	formate dehydrogenase (NAD+) activity
FNV65_RS42430	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FNV65_RS42440	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FNV65_RS42475	COG1940	carbohydrate kinase activity
FNV65_RS42480	COG1129	ABC transporter
FNV65_RS42485	COG1172	Belongs to the binding-protein-dependent transport system permease family
FNV65_RS42490	COG1879	ABC-type sugar transport system periplasmic component
FNV65_RS42495	COG0673	inositol 2-dehydrogenase activity
FNV65_RS42505	COG3507	Belongs to the glycosyl hydrolase 43 family
FNV65_RS42535	COG0084	hydrolase, TatD family'
FNV65_RS42560	COG2223	nitrite transmembrane transporter activity
FNV65_RS42570	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNV65_RS42580	COG0045	succinate-CoA ligase (ADP-forming) activity
FNV65_RS42590	COG1012	belongs to the aldehyde dehydrogenase family
FNV65_RS42650	COG0789	Transcriptional regulator
FNV65_RS42690	COG0402	S-adenosylhomocysteine deaminase activity
FNV65_RS42720	COG2226	methyltransferase
FNV65_RS42740	COG4044	May play a role in the intracellular transport of hydrophobic ligands
FNV65_RS42750	COG4221	oxidoreductase activity
FNV65_RS42790	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FNV65_RS42795	COG0254	rRNA binding
FNV65_RS42810	COG4585	Histidine kinase
FNV65_RS42815	COG2197	response regulator
FNV65_RS42850	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FNV65_RS42855	COG2072	flavoprotein involved in K transport
FNV65_RS42875	COG0022	dehydrogenase e1 component
FNV65_RS42880	COG1309	transcriptional regulator
FNV65_RS42885	COG1960	acyl-CoA dehydrogenase activity
FNV65_RS42890	COG1063	alcohol dehydrogenase
FNV65_RS42905	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS42910	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS42915	COG0745	RESPONSE REGULATOR receiver
FNV65_RS42970	COG0542	response to heat
FNV65_RS43000	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNV65_RS43010	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
FNV65_RS43025	COG1063	alcohol dehydrogenase
FNV65_RS43035	COG0745	RESPONSE REGULATOR receiver
FNV65_RS43045	COG0477	Major facilitator Superfamily
FNV65_RS43050	COG2124	cytochrome p450
FNV65_RS43070	COG0477	Major facilitator Superfamily
FNV65_RS43110	COG2353	YceI-like domain
FNV65_RS43120	COG0765	amino acid transport
FNV65_RS43125	COG1126	abc transporter atp-binding protein
FNV65_RS43130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNV65_RS43140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV65_RS43145	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV65_RS43150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV65_RS43155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV65_RS43170	COG0508	dehydrogenase complex catalyzes the overall conversion of
FNV65_RS43170	COG0596	Alpha beta hydrolase
FNV65_RS43180	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FNV65_RS43205	COG0438	transferase activity, transferring glycosyl groups
FNV65_RS43225	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FNV65_RS43255	COG0477	Major facilitator Superfamily
FNV65_RS43265	COG3467	pyridoxamine 5'-phosphate
FNV65_RS43280	COG0477	Major facilitator Superfamily
FNV65_RS43290	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FNV65_RS43295	COG1082	Xylose isomerase domain protein TIM barrel
FNV65_RS43295	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FNV65_RS43310	COG0588	phosphoglycerate mutase activity
FNV65_RS43315	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FNV65_RS43320	COG0166	Belongs to the GPI family
FNV65_RS43335	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FNV65_RS43370	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS43395	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FNV65_RS43400	COG3250	beta-galactosidase activity
FNV65_RS43405	COG0395	ABC-type sugar transport system, permease component
FNV65_RS43410	COG1175	transmembrane transport
FNV65_RS43420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNV65_RS43425	COG1349	DNA-binding transcription factor activity
FNV65_RS43430	COG1486	melibiose metabolic process
FNV65_RS43440	COG3469	chitinase activity
FNV65_RS43450	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FNV65_RS43505	COG3842	ATPase activity
FNV65_RS43510	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FNV65_RS43515	COG1176	ABC-type spermidine putrescine transport system, permease component I
FNV65_RS43520	COG1177	transmembrane transport
FNV65_RS43540	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FNV65_RS43545	COG3938	Belongs to the proline racemase family
FNV65_RS43580	COG1175	transmembrane transport
FNV65_RS43585	COG0395	ABC-type sugar transport system, permease component
FNV65_RS43590	COG0366	Alpha amylase catalytic
FNV65_RS43600	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNV65_RS43605	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNV65_RS43710	COG3511	phospholipase C
FNV65_RS43785	COG0494	nUDIX hydrolase
FNV65_RS43865	COG3328	transposase activity
FNV65_RS43875	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FNV65_RS43880	COG0477	Major facilitator Superfamily
FNV65_RS43895	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FNV65_RS43905	COG3485	protocatechuate 3,4-dioxygenase
FNV65_RS43910	COG3485	protocatechuate 3,4-dioxygenase
FNV65_RS43915	COG0183	Belongs to the thiolase family
FNV65_RS43930	COG1846	Transcriptional regulator
FNV65_RS43940	COG0714	Associated with various cellular activities
FNV65_RS43955	COG1793	dna ligase
FNV65_RS44035	COG1834	amidinotransferase
FNV65_RS44040	COG0488	(ABC) transporter
FNV65_RS44050	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FNV65_RS44070	COG1515	deoxyribonuclease V activity
FNV65_RS44075	COG3268	Saccharopine dehydrogenase
FNV65_RS44080	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNV65_RS44085	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV65_RS44095	COG0183	Belongs to the thiolase family
FNV65_RS44100	COG1024	Enoyl-CoA hydratase
FNV65_RS44100	COG1250	3-hydroxyacyl-CoA dehydrogenase
FNV65_RS44105	COG0789	Transcriptional regulator
FNV65_RS44110	COG1113	amino acid transport
FNV65_RS44120	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FNV65_RS44130	COG2936	dipeptidyl-peptidase activity
FNV65_RS44145	COG0488	(ABC) transporter
FNV65_RS44155	COG2183	response to ionizing radiation
FNV65_RS44165	COG4977	sequence-specific DNA binding
FNV65_RS44175	COG1024	Enoyl-CoA hydratase
FNV65_RS44190	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FNV65_RS44195	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FNV65_RS44195	COG4106	trans-aconitate 2-methyltransferase activity
FNV65_RS44240	COG1134	teichoic acid transport
FNV65_RS44245	COG1562	ergosterol biosynthetic process
FNV65_RS44255	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FNV65_RS44265	COG1657	PFAM Prenyltransferase squalene oxidase
FNV65_RS44280	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FNV65_RS44285	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FNV65_RS44305	COG2365	Tyrosine phosphatase family
FNV65_RS44320	COG3401	FG-GAP repeat protein
FNV65_RS44330	COG2755	lipolytic protein G-D-S-L family
FNV65_RS44345	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FNV65_RS44390	COG1063	alcohol dehydrogenase
FNV65_RS44395	COG0156	8-amino-7-oxononanoate synthase activity
FNV65_RS44400	COG0583	DNA-binding transcription factor activity
FNV65_RS44435	COG3958	Transketolase
FNV65_RS44440	COG3959	Transketolase, thiamine diphosphate binding domain
FNV65_RS44465	COG1132	(ABC) transporter
FNV65_RS44495	COG3033	Beta-eliminating lyase
FNV65_RS44515	COG1937	Protein conserved in bacteria
FNV65_RS44535	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FNV65_RS44555	COG3239	Fatty acid desaturase
FNV65_RS44565	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FNV65_RS44670	COG1454	alcohol dehydrogenase
FNV65_RS44680	COG0351	phosphomethylpyrimidine kinase
FNV65_RS44685	COG0702	epimerase
FNV65_RS44735	COG1595	DNA-templated transcription, initiation
FNV65_RS44745	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FNV65_RS44760	COG1053	succinate dehydrogenase
FNV65_RS44765	COG1764	response to oxidative stress
FNV65_RS44770	COG1595	DNA-templated transcription, initiation
FNV65_RS44830	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FNV65_RS44855	COG2838	Isocitrate dehydrogenase
FNV65_RS44860	COG0668	transmembrane transport
FNV65_RS44865	COG1024	Enoyl-CoA hydratase
FNV65_RS44880	COG2409	Drug exporters of the RND superfamily
FNV65_RS44885	COG1309	transcriptional regulator
FNV65_RS44890	COG0473	3-isopropylmalate dehydrogenase activity
FNV65_RS44900	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FNV65_RS44915	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FNV65_RS44930	COG3483	tryptophan 2,3-dioxygenase activity
FNV65_RS44945	COG0475	glutathione-regulated potassium exporter activity
FNV65_RS44950	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FNV65_RS44965	COG2264	protein methyltransferase activity
FNV65_RS44995	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FNV65_RS45010	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FNV65_RS45015	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FNV65_RS45020	COG0697	spore germination
FNV65_RS45025	COG1509	lysine 2,3-aminomutase activity
FNV65_RS45035	COG0579	oxidoreductase
FNV65_RS45085	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FNV65_RS45105	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FNV65_RS45125	COG0297	glycogen (starch) synthase activity
FNV65_RS45130	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FNV65_RS45150	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FNV65_RS45155	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS45165	COG0701	Predicted permease
FNV65_RS45205	COG1175	transmembrane transport
FNV65_RS45210	COG0395	ABC-type sugar transport system, permease component
FNV65_RS45230	COG2186	Transcriptional regulator
FNV65_RS45235	COG1879	ABC-type sugar transport system periplasmic component
FNV65_RS45240	COG1129	ABC transporter
FNV65_RS45245	COG1172	Belongs to the binding-protein-dependent transport system permease family
FNV65_RS45250	COG4948	Mandelate Racemase Muconate Lactonizing
FNV65_RS45255	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS45290	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FNV65_RS45325	COG0726	polysaccharide deacetylase
FNV65_RS45375	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS45390	COG1053	succinate dehydrogenase
FNV65_RS45395	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FNV65_RS45415	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV65_RS45430	COG0667	Aldo Keto reductase
FNV65_RS45465	COG1595	DNA-templated transcription, initiation
FNV65_RS45505	COG2814	Major facilitator Superfamily
FNV65_RS45510	COG0583	DNA-binding transcription factor activity
FNV65_RS45515	COG0583	DNA-binding transcription factor activity
FNV65_RS45530	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FNV65_RS45535	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FNV65_RS45540	COG2080	2 iron, 2 sulfur cluster binding
FNV65_RS45555	COG0667	Aldo Keto reductase
FNV65_RS45585	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
FNV65_RS45590	COG0121	glutamine amidotransferase
FNV65_RS45595	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FNV65_RS45600	COG3572	ergothioneine biosynthetic process
FNV65_RS45620	COG2268	Band 7 protein
FNV65_RS45635	COG1609	Transcriptional regulator
FNV65_RS45650	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FNV65_RS45660	COG0242	peptide deformylase activity
FNV65_RS45740	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FNV65_RS45755	COG1408	metallophosphoesterase
FNV65_RS45760	COG2226	methyltransferase
FNV65_RS45810	COG2378	regulation of single-species biofilm formation
FNV65_RS45835	COG1609	Transcriptional regulator
FNV65_RS45850	COG0395	ABC-type sugar transport system, permease component
FNV65_RS45885	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FNV65_RS45905	COG1309	transcriptional regulator
FNV65_RS45910	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS45945	COG0163	prenyltransferase activity
FNV65_RS45980	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FNV65_RS46000	COG2318	DinB family
FNV65_RS46020	COG1733	regulation of RNA biosynthetic process
FNV65_RS46030	COG2366	antibiotic biosynthetic process
FNV65_RS46035	COG1073	alpha beta
FNV65_RS46085	COG0583	DNA-binding transcription factor activity
FNV65_RS46090	COG2130	NADP-dependent
FNV65_RS46115	COG2072	flavoprotein involved in K transport
FNV65_RS46120	COG0667	Aldo Keto reductase
FNV65_RS46125	COG1902	pentaerythritol trinitrate reductase activity
FNV65_RS46145	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS46160	COG0183	Belongs to the thiolase family
FNV65_RS46180	COG3485	protocatechuate 3,4-dioxygenase
FNV65_RS46190	COG2909	trisaccharide binding
FNV65_RS46215	COG0778	Nitroreductase
FNV65_RS46270	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FNV65_RS46290	COG3537	Alpha-1,2-mannosidase
FNV65_RS46305	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV65_RS46325	COG0477	Major facilitator Superfamily
FNV65_RS46345	COG0006	proline dipeptidase activity
FNV65_RS46350	COG3291	Pkd domain containing protein
FNV65_RS46360	COG0673	inositol 2-dehydrogenase activity
FNV65_RS46375	COG1609	Transcriptional regulator
FNV65_RS46380	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FNV65_RS46415	COG1122	ATPase activity
FNV65_RS46420	COG1122	ATPase activity
FNV65_RS46425	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FNV65_RS46450	COG0561	phosphatase activity
FNV65_RS46525	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FNV65_RS46530	COG2151	metal-sulfur cluster biosynthetic enzyme
FNV65_RS46535	COG3396	Phenylacetate-CoA oxygenase
FNV65_RS46540	COG3460	Phenylacetate-CoA oxygenase
FNV65_RS46545	COG3396	Phenylacetate-CoA oxygenase
FNV65_RS46550	COG1250	3-hydroxyacyl-CoA dehydrogenase
FNV65_RS46570	COG2050	protein possibly involved in aromatic compounds catabolism
FNV65_RS46585	COG0531	amino acid
FNV65_RS46655	COG2226	methyltransferase
FNV65_RS46680	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FNV65_RS46680	COG1024	Enoyl-CoA hydratase
FNV65_RS46690	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
FNV65_RS46720	COG0375	protein maturation
FNV65_RS46725	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FNV65_RS46730	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FNV65_RS46735	COG0298	carbon dioxide binding
FNV65_RS46740	COG0409	Hydrogenase expression formation protein
FNV65_RS46745	COG0309	Hydrogenase expression formation protein (HypE)
FNV65_RS46775	COG1141	Ferredoxin
FNV65_RS46805	COG1136	(ABC) transporter
FNV65_RS46810	COG1174	glycine betaine transport
FNV65_RS46815	COG1174	glycine betaine transport
FNV65_RS46835	COG0517	IMP dehydrogenase activity
FNV65_RS46835	COG1125	glycine betaine transport
FNV65_RS46840	COG1556	Lactate utilization protein
FNV65_RS46845	COG1139	Iron-sulfur cluster binding protein
FNV65_RS46850	COG0247	lactate metabolic process
FNV65_RS46855	COG1070	Carbohydrate kinase
FNV65_RS46860	COG3347	Dehydrogenase
FNV65_RS46860	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS46870	COG1129	ABC transporter
FNV65_RS46905	COG1609	Transcriptional regulator
FNV65_RS46915	COG1595	DNA-templated transcription, initiation
FNV65_RS46920	COG1357	PFAM Pentapeptide repeats (8 copies)
FNV65_RS46930	COG1309	transcriptional regulator
FNV65_RS46940	COG2706	6-phosphogluconolactonase activity
FNV65_RS46965	COG3321	synthase
FNV65_RS46965	COG0604	alcohol dehydrogenase
FNV65_RS46965	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS46990	COG2723	6-phospho-beta-galactosidase activity
FNV65_RS46995	COG0395	ABC-type sugar transport system, permease component
FNV65_RS47000	COG1175	transmembrane transport
FNV65_RS47005	COG2182	Extracellular solute-binding protein
FNV65_RS47030	COG2267	carboxylic ester hydrolase activity
FNV65_RS47040	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FNV65_RS47040	COG1796	DNA polymerase
FNV65_RS47090	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FNV65_RS47115	COG0515	serine threonine protein kinase
FNV65_RS47165	COG0640	Transcriptional regulator
FNV65_RS47175	COG0772	Belongs to the SEDS family
FNV65_RS47210	COG1316	TRANSCRIPTIONal
FNV65_RS47220	COG1278	Cold shock
FNV65_RS47255	COG0515	serine threonine protein kinase
FNV65_RS47265	COG1132	(ABC) transporter
FNV65_RS47270	COG1132	(ABC) transporter
FNV65_RS47275	COG2197	response regulator
FNV65_RS47280	COG0531	amino acid
FNV65_RS47390	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
FNV65_RS47390	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FNV65_RS47415	COG1609	Transcriptional regulator
FNV65_RS47440	COG1621	beta-fructofuranosidase activity
FNV65_RS47520	COG2172	sigma factor antagonist activity
FNV65_RS47520	COG2208	phosphoserine phosphatase activity
FNV65_RS47520	COG1366	Belongs to the anti-sigma-factor antagonist family
FNV65_RS47535	COG0789	Transcriptional regulator
FNV65_RS47555	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FNV65_RS47650	COG2318	DinB family
FNV65_RS47680	COG0745	RESPONSE REGULATOR receiver
FNV65_RS47740	COG2132	Multicopper oxidase
FNV65_RS47750	COG2226	methyltransferase
FNV65_RS47765	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FNV65_RS47785	COG1012	belongs to the aldehyde dehydrogenase family
FNV65_RS47825	COG0318	PFAM AMP-dependent synthetase and ligase
FNV65_RS47835	COG0531	amino acid
FNV65_RS47875	COG2124	cytochrome p450
FNV65_RS47915	COG0596	Alpha beta hydrolase
FNV65_RS47920	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FNV65_RS47920	COG1672	PFAM Archaeal ATPase
FNV65_RS47950	COG3250	beta-galactosidase activity
FNV65_RS47955	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FNV65_RS47980	COG0640	Transcriptional regulator
FNV65_RS48015	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FNV65_RS48045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV65_RS48060	COG4209	transmembrane transport
FNV65_RS48065	COG0395	ABC-type sugar transport system, permease component
FNV65_RS48075	COG1609	Transcriptional regulator
FNV65_RS48090	COG0671	phosphoesterase, PA-phosphatase related
FNV65_RS48105	COG3832	glyoxalase III activity
FNV65_RS48150	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FNV65_RS48150	COG2755	lipolytic protein G-D-S-L family
FNV65_RS48165	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FNV65_RS48215	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FNV65_RS48230	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FNV65_RS48245	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FNV65_RS48270	COG1132	(ABC) transporter
FNV65_RS48315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNV65_RS48350	COG1940	carbohydrate kinase activity
FNV65_RS48350	COG1846	Transcriptional regulator
FNV65_RS48370	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
FNV65_RS48395	COG1595	DNA-templated transcription, initiation
FNV65_RS48440	COG4948	Mandelate Racemase Muconate Lactonizing
FNV65_RS48450	COG0583	DNA-binding transcription factor activity
FNV65_RS48500	COG1404	Belongs to the peptidase S8 family
FNV65_RS48520	COG2318	DinB family
FNV65_RS48555	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FNV65_RS48560	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FNV65_RS48570	COG2409	Drug exporters of the RND superfamily
FNV65_RS48600	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS48605	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS48665	COG1802	Transcriptional regulator
FNV65_RS48725	COG0384	phenazine biosynthesis protein PhzF
FNV65_RS48735	COG0583	DNA-binding transcription factor activity
FNV65_RS48760	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS48810	COG1278	Cold shock
FNV65_RS48835	COG3552	Protein containing von Willebrand factor type A (VWA) domain
FNV65_RS48840	COG0714	Associated with various cellular activities
FNV65_RS48870	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FNV65_RS48880	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FNV65_RS48890	COG0596	Alpha beta hydrolase
FNV65_RS48905	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FNV65_RS48920	COG1940	carbohydrate kinase activity
FNV65_RS48930	COG1175	transmembrane transport
FNV65_RS48935	COG0395	ABC-type sugar transport system, permease component
FNV65_RS48960	COG2340	Cysteine-rich secretory protein family
FNV65_RS49005	COG3469	chitinase activity
FNV65_RS49015	COG3548	integral membrane protein
FNV65_RS49025	COG0667	Aldo Keto reductase
FNV65_RS49040	COG3537	Alpha-1,2-mannosidase
FNV65_RS49065	COG1129	ABC transporter
FNV65_RS49085	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS49090	COG1960	acyl-CoA dehydrogenase activity
FNV65_RS49095	COG1024	Enoyl-CoA hydratase
FNV65_RS49105	COG0183	Belongs to the thiolase family
FNV65_RS49110	COG1960	acyl-CoA dehydrogenase activity
FNV65_RS49120	COG1960	acyl-CoA dehydrogenase activity
FNV65_RS49125	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS49130	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS49135	COG1024	Enoyl-CoA hydratase
FNV65_RS49165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNV65_RS49180	COG1228	amidohydrolase
FNV65_RS49185	COG0515	serine threonine protein kinase
FNV65_RS49195	COG3250	beta-galactosidase activity
FNV65_RS49225	COG0730	response to heat
FNV65_RS49230	COG1937	Protein conserved in bacteria
FNV65_RS49270	COG1175	transmembrane transport
FNV65_RS49295	COG3345	alpha-galactosidase
FNV65_RS49305	COG0667	Aldo Keto reductase
FNV65_RS49310	COG1335	isochorismatase
FNV65_RS49330	COG3852	Histidine kinase
FNV65_RS49335	COG0492	ferredoxin-NADP+ reductase activity
FNV65_RS49365	COG3290	protein histidine kinase activity
FNV65_RS49375	COG2814	Major facilitator Superfamily
FNV65_RS49400	COG1716	ATPase activity
FNV65_RS49400	COG1131	(ABC) transporter
FNV65_RS49400	COG0842	Transport permease protein
FNV65_RS49435	COG0739	heme binding
FNV65_RS49455	COG0583	DNA-binding transcription factor activity
FNV65_RS49460	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FNV65_RS49480	COG2197	response regulator
FNV65_RS49500	COG0395	ABC-type sugar transport system, permease component
FNV65_RS49515	COG1335	isochorismatase
FNV65_RS49530	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FNV65_RS49550	COG5002	protein histidine kinase activity
FNV65_RS49560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNV65_RS49565	COG1053	succinate dehydrogenase
FNV65_RS49575	COG2318	DinB family
FNV65_RS49585	COG2318	DinB family
FNV65_RS49630	COG0596	Alpha beta hydrolase
FNV65_RS49635	COG1017	nitric oxide dioxygenase activity
FNV65_RS49635	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FNV65_RS49660	COG1595	DNA-templated transcription, initiation
FNV65_RS49680	COG0745	RESPONSE REGULATOR receiver
FNV65_RS49710	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FNV65_RS49720	COG2080	2 iron, 2 sulfur cluster binding
FNV65_RS49720	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FNV65_RS49745	COG2197	response regulator
FNV65_RS49770	COG4191	Histidine kinase
FNV65_RS49780	COG0516	GMP reductase activity
FNV65_RS49780	COG0517	IMP dehydrogenase activity
FNV65_RS49830	COG0589	response to stress
FNV65_RS49835	COG2326	polyphosphate kinase activity
FNV65_RS49840	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
FNV65_RS49845	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FNV65_RS49865	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FNV65_RS49865	COG1042	CoA-binding domain protein
FNV65_RS49865	COG0045	succinate-CoA ligase (ADP-forming) activity
FNV65_RS49890	COG0517	IMP dehydrogenase activity
FNV65_RS49890	COG0516	GMP reductase activity
FNV65_RS49905	COG0574	Belongs to the PEP-utilizing enzyme family
FNV65_RS49905	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FNV65_RS49945	COG0516	GMP reductase activity
FNV65_RS49945	COG0517	IMP dehydrogenase activity
FNV65_RS49965	COG2239	Acts as a magnesium transporter
FNV65_RS50025	COG1063	alcohol dehydrogenase
FNV65_RS50040	COG0531	amino acid
FNV65_RS50045	COG2235	arginine
FNV65_RS50050	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FNV65_RS50055	COG0549	Belongs to the carbamate kinase family
FNV65_RS50065	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FNV65_RS50095	COG1309	transcriptional regulator
FNV65_RS50100	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS50115	COG1278	Cold shock
FNV65_RS50120	COG0513	Belongs to the DEAD box helicase family
FNV65_RS50170	COG2274	protein secretion by the type I secretion system
FNV65_RS50215	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FNV65_RS50220	COG2226	methyltransferase
FNV65_RS50225	COG5640	endopeptidase activity
FNV65_RS50240	COG0789	Transcriptional regulator
FNV65_RS50270	COG1132	(ABC) transporter
FNV65_RS50280	COG2318	DinB family
FNV65_RS50300	COG1012	belongs to the aldehyde dehydrogenase family
FNV65_RS50305	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FNV65_RS50310	COG1414	Transcriptional regulator
FNV65_RS50325	COG4106	trans-aconitate 2-methyltransferase activity
FNV65_RS50355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV65_RS50360	COG1335	isochorismatase
FNV65_RS50390	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FNV65_RS50455	COG2208	phosphoserine phosphatase activity
FNV65_RS50470	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FNV65_RS50505	COG0583	DNA-binding transcription factor activity
FNV65_RS50510	COG0243	molybdopterin cofactor binding
FNV65_RS50545	COG2837	iron assimilation
FNV65_RS50555	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS50560	COG0657	acetylesterase activity
FNV65_RS50570	COG2207	Transcriptional regulator
FNV65_RS50580	COG0745	RESPONSE REGULATOR receiver
FNV65_RS50585	COG2205	protein histidine kinase activity
FNV65_RS50605	COG0640	Transcriptional regulator
FNV65_RS50685	COG1309	transcriptional regulator
FNV65_RS50700	COG1309	transcriptional regulator
FNV65_RS50705	COG1064	alcohol dehydrogenase
FNV65_RS50720	COG1172	Belongs to the binding-protein-dependent transport system permease family
FNV65_RS50725	COG1129	ABC transporter
FNV65_RS50735	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS50790	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS50795	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS50825	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNV65_RS50840	COG1522	sequence-specific DNA binding
FNV65_RS50890	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FNV65_RS50915	COG1595	DNA-templated transcription, initiation
FNV65_RS50945	COG2267	carboxylic ester hydrolase activity
FNV65_RS50960	COG0531	amino acid
FNV65_RS50970	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS50975	COG4221	oxidoreductase activity
FNV65_RS51000	COG4941	Belongs to the sigma-70 factor family
FNV65_RS51005	COG3795	YCII-related domain
FNV65_RS51050	COG1309	transcriptional regulator
FNV65_RS51055	COG0667	Aldo Keto reductase
FNV65_RS51085	COG2124	cytochrome p450
FNV65_RS51110	COG4585	Histidine kinase
FNV65_RS51115	COG2197	response regulator
FNV65_RS51145	COG2197	response regulator
FNV65_RS51150	COG4585	Histidine kinase
FNV65_RS51155	COG4552	Acetyltransferase involved in intracellular survival and related
FNV65_RS51190	COG0596	Alpha beta hydrolase
FNV65_RS51210	COG2197	response regulator
FNV65_RS51225	COG0446	pyridine nucleotide-disulphide oxidoreductase
FNV65_RS51225	COG1902	pentaerythritol trinitrate reductase activity
FNV65_RS51230	COG1012	belongs to the aldehyde dehydrogenase family
FNV65_RS51235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FNV65_RS51245	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV65_RS51260	COG0583	DNA-binding transcription factor activity
FNV65_RS51265	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS51285	COG0745	RESPONSE REGULATOR receiver
FNV65_RS51385	COG1309	transcriptional regulator
FNV65_RS51395	COG1309	transcriptional regulator
FNV65_RS51435	COG3173	Aminoglycoside phosphotransferase
FNV65_RS51460	COG1012	belongs to the aldehyde dehydrogenase family
FNV65_RS51490	COG3321	synthase
FNV65_RS51490	COG0604	alcohol dehydrogenase
FNV65_RS51540	COG0326	Molecular chaperone. Has ATPase activity
FNV65_RS51550	COG2409	Drug exporters of the RND superfamily
FNV65_RS51565	COG2072	flavoprotein involved in K transport
FNV65_RS51575	COG1012	belongs to the aldehyde dehydrogenase family
FNV65_RS51650	COG4977	sequence-specific DNA binding
FNV65_RS51670	COG1024	Enoyl-CoA hydratase
FNV65_RS51715	COG0446	pyridine nucleotide-disulphide oxidoreductase
FNV65_RS51715	COG1902	pentaerythritol trinitrate reductase activity
FNV65_RS51730	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FNV65_RS51735	COG4221	oxidoreductase activity
FNV65_RS51745	COG0477	Major facilitator Superfamily
FNV65_RS51760	COG0477	Major facilitator Superfamily
FNV65_RS51765	COG0477	Major facilitator Superfamily
FNV65_RS51785	COG1609	Transcriptional regulator
FNV65_RS51810	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FNV65_RS51815	COG0667	Aldo Keto reductase
FNV65_RS51850	COG0300	oxidoreductase activity
FNV65_RS51860	COG1309	transcriptional regulator
FNV65_RS51885	COG1802	Transcriptional regulator
FNV65_RS51890	COG2205	protein histidine kinase activity
FNV65_RS51895	COG0745	RESPONSE REGULATOR receiver
FNV65_RS51900	COG2409	Drug exporters of the RND superfamily
FNV65_RS51985	COG2261	transglycosylase associated protein
FNV65_RS51990	COG0640	Transcriptional regulator
FNV65_RS52000	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FNV65_RS52015	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FNV65_RS52070	COG0179	Fumarylacetoacetate (FAA) hydrolase
FNV65_RS52085	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FNV65_RS52110	COG0202	RNA polymerase activity
FNV65_RS52125	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FNV65_RS52175	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FNV65_RS52210	COG4977	sequence-specific DNA binding
FNV65_RS52225	COG0477	Major facilitator Superfamily
FNV65_RS52270	COG2197	response regulator
FNV65_RS52280	COG2272	Belongs to the type-B carboxylesterase lipase family
FNV65_RS52325	COG2770	Histidine kinase
FNV65_RS52325	COG2208	phosphoserine phosphatase activity
FNV65_RS52470	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FNV65_RS52515	COG0604	alcohol dehydrogenase
FNV65_RS52515	COG3321	synthase
FNV65_RS52515	COG4221	oxidoreductase activity
FNV65_RS52515	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FNV65_RS52540	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS52610	COG4585	Histidine kinase
FNV65_RS52635	COG2135	peptidase activity
FNV65_RS52800	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FNV65_RS52845	COG3118	belongs to the thioredoxin family
FNV65_RS52895	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNV65_RS52900	COG0483	inositol monophosphate 1-phosphatase activity
FNV65_RS52905	COG0583	DNA-binding transcription factor activity
FNV65_RS52930	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FNV65_RS52955	COG0563	adenylate kinase activity
FNV65_RS52995	COG2159	amidohydrolase
FNV65_RS53020	COG2226	methyltransferase
FNV65_RS53025	COG3328	transposase activity
FNV65_RS53065	COG2197	response regulator
FNV65_RS53160	COG4584	PFAM Integrase catalytic
FNV65_RS53165	COG1484	DNA-dependent DNA replication
FNV65_RS53280	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FNV65_RS53300	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FNV65_RS53300	COG0300	oxidoreductase activity
FNV65_RS53300	COG3321	synthase
FNV65_RS53300	COG4221	oxidoreductase activity
FNV65_RS53320	COG0318	PFAM AMP-dependent synthetase and ligase
FNV65_RS53325	COG2197	response regulator
FNV65_RS53350	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FNV65_RS53355	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FNV65_RS53360	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS53365	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FNV65_RS53370	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FNV65_RS53375	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FNV65_RS53380	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FNV65_RS53385	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FNV65_RS53390	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FNV65_RS53400	COG0667	Aldo Keto reductase
FNV65_RS53415	COG1022	Amp-dependent synthetase and ligase
FNV65_RS53440	COG0477	Major facilitator Superfamily
FNV65_RS53445	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FNV65_RS53535	COG1335	isochorismatase
FNV65_RS53540	COG3619	membrane
FNV65_RS53580	COG3547	Transposase (IS116 IS110 IS902 family)
FNV65_RS53625	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FNV65_RS53645	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FNV65_RS53710	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FNV65_RS53715	COG3387	PFAM Glycoside hydrolase 15-related
FNV65_RS53720	COG3547	Transposase (IS116 IS110 IS902 family)
FNV65_RS53725	COG2197	response regulator
FNV65_RS53730	COG4585	Histidine kinase
FNV65_RS53760	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FNV65_RS53765	COG1595	DNA-templated transcription, initiation
FNV65_RS53830	COG0248	Ppx GppA phosphatase
FNV65_RS53945	COG3321	synthase
FNV65_RS53945	COG0604	alcohol dehydrogenase
FNV65_RS53950	COG0657	acetylesterase activity
FNV65_RS54020	COG4977	sequence-specific DNA binding
FNV65_RS54085	COG2207	Transcriptional regulator
FNV65_RS54105	COG2801	Transposase and inactivated derivatives
FNV65_RS54110	COG2826	transposase and inactivated derivatives, IS30 family
FNV65_RS54205	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FNV65_RS54250	COG1960	acyl-CoA dehydrogenase activity
FNV65_RS54255	COG1454	alcohol dehydrogenase
FNV65_RS54270	COG0583	DNA-binding transcription factor activity
FNV65_RS54275	COG0183	Belongs to the thiolase family
FNV65_RS54285	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FNV65_RS54300	COG0006	proline dipeptidase activity
FNV65_RS54305	COG2084	Dehydrogenase
FNV65_RS54320	COG1609	Transcriptional regulator
FNV65_RS54325	COG2188	Transcriptional regulator
FNV65_RS54335	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FNV65_RS54340	COG0508	dehydrogenase complex catalyzes the overall conversion of
FNV65_RS54365	COG1609	Transcriptional regulator
FNV65_RS54390	COG1131	(ABC) transporter
FNV65_RS54415	COG1335	isochorismatase
FNV65_RS54420	COG3619	membrane
FNV65_RS54455	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNV65_RS54465	COG1116	anion transmembrane transporter activity
FNV65_RS54475	COG2353	YceI-like domain
FNV65_RS54480	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS54575	COG3328	transposase activity
FNV65_RS54580	COG3328	transposase activity
FNV65_RS54590	COG0069	glutamate synthase activity
FNV65_RS54655	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FNV65_RS54660	COG1028	Short-chain dehydrogenase reductase Sdr
FNV65_RS54680	COG0477	Major facilitator Superfamily
FNV65_RS54690	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNV65_RS54695	COG1024	Enoyl-CoA hydratase
FNV65_RS54765	COG0583	DNA-binding transcription factor activity
FNV65_RS54770	COG0028	Belongs to the TPP enzyme family
FNV65_RS54775	COG0427	acetyl-CoA hydrolase
FNV65_RS54780	COG2301	Belongs to the HpcH HpaI aldolase family
FNV65_RS54785	COG2030	dehydratase
FNV65_RS54790	COG0583	DNA-binding transcription factor activity
FNV65_RS54805	COG2814	Major facilitator Superfamily
FNV65_RS54825	COG1335	isochorismatase
FNV65_RS54835	COG2186	Transcriptional regulator
FNV65_RS54865	COG0477	Major facilitator Superfamily
FNV65_RS54875	COG2186	Transcriptional regulator
FNV65_RS54880	COG1335	isochorismatase
FNV65_RS54920	COG2826	transposase and inactivated derivatives, IS30 family
FNV65_RS54945	COG0281	malic enzyme
FNV65_RS54950	COG0114	fumarate hydratase activity